locus-tag	class	description
K0V03_00020	COG0116	Belongs to the methyltransferase superfamily
K0V03_00035	COG4474	Belongs to the UPF0398 family
K0V03_00050	COG3359	exonuclease
K0V03_00055	COG1111	helicase
K0V03_00055	COG1205	dead DEAH box helicase
K0V03_00060	COG2190	(PTS) system
K0V03_00065	COG0071	Belongs to the small heat shock protein (HSP20) family
K0V03_00100	COG3331	DNA recombination
K0V03_00105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K0V03_00105	COG4499	WXG100 protein secretion system (Wss), protein YukC
K0V03_00115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K0V03_00120	COG3935	DnaD domain protein
K0V03_00125	COG0017	Asparaginyl-tRNA synthetase
K0V03_00130	COG0436	Aminotransferase
K0V03_00135	COG5353	protein conserved in bacteria
K0V03_00145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K0V03_00145	COG1199	ATP-dependent helicase activity
K0V03_00150	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
K0V03_00155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K0V03_00160	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K0V03_00165	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
K0V03_00165	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
K0V03_00170	COG0617	tRNA 3'-terminal CCA addition
K0V03_00175	COG0438	transferase activity, transferring glycosyl groups
K0V03_00180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K0V03_00185	COG1803	Methylglyoxal synthase
K0V03_00190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K0V03_00195	COG1694	Mazg nucleotide pyrophosphohydrolase
K0V03_00200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K0V03_00210	COG4347	Protein of unknown function (DUF1405)
K0V03_00215	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K0V03_00215	COG2010	Cytochrome c
K0V03_00220	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K0V03_00225	COG0723	plastoquinol--plastocyanin reductase activity
K0V03_00235	COG5582	Belongs to the UPF0302 family
K0V03_00240	COG0457	Tetratricopeptide repeat
K0V03_00245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K0V03_00250	COG0287	Prephenate dehydrogenase
K0V03_00260	COG0159	tryptophan synthase activity
K0V03_00265	COG0133	tryptophan synthase activity
K0V03_00270	COG0135	phosphoribosylanthranilate isomerase activity
K0V03_00280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K0V03_00285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K0V03_00290	COG4401	Chorismate mutase type I
K0V03_00295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K0V03_00300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K0V03_00305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K0V03_00310	COG0105	UTP biosynthetic process
K0V03_00315	COG0142	geranyltranstransferase activity
K0V03_00320	COG2226	methyltransferase
K0V03_00325	COG0142	geranyltranstransferase activity
K0V03_00335	COG0302	gtp cyclohydrolase
K0V03_00340	COG0776	regulation of translation
K0V03_00345	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K0V03_00360	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K0V03_00365	COG1160	GTP binding
K0V03_00390	COG1304	FMN binding
K0V03_00395	COG0539	negative regulation of cytoplasmic translation
K0V03_00400	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K0V03_00410	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
K0V03_00415	COG2959	enzyme of heme biosynthesis
K0V03_00420	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_00420	COG3773	Cell wall hydrolase
K0V03_00425	COG2339	peptidase activity
K0V03_00430	COG0492	ferredoxin-NADP+ reductase activity
K0V03_00435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K0V03_00440	COG4862	establishment of competence for transformation
K0V03_00445	COG1408	metallophosphoesterase
K0V03_00455	COG1388	LysM domain
K0V03_00460	COG1266	CAAX protease self-immunity
K0V03_00465	COG0514	ATP-dependent DNA helicase (RecQ)
K0V03_00470	COG4955	Helix-turn-helix domain
K0V03_00475	COG1141	Ferredoxin
K0V03_00480	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K0V03_00485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K0V03_00490	COG0710	3-dehydroquinate dehydratase activity
K0V03_00500	COG1595	DNA-templated transcription, initiation
K0V03_00505	COG5002	protein histidine kinase activity
K0V03_00510	COG0745	RESPONSE REGULATOR receiver
K0V03_00515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K0V03_00520	COG1333	cytochrome c biogenesis protein
K0V03_00525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K0V03_00530	COG1187	pseudouridine synthase activity
K0V03_00535	COG0700	Nucleoside recognition
K0V03_00540	COG2715	membrane protein required for spore maturation
K0V03_00545	COG1686	Belongs to the peptidase S11 family
K0V03_00555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K0V03_00560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K0V03_00565	COG1547	Domain of unknown function (DUF309)
K0V03_00570	COG0456	acetyltransferase
K0V03_00575	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K0V03_00580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K0V03_00580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K0V03_00585	COG0307	riboflavin synthase, alpha
K0V03_00590	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K0V03_00590	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K0V03_00600	COG0681	Belongs to the peptidase S26 family
K0V03_00610	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
K0V03_00660	COG3012	SEC-C Motif Domain Protein
K0V03_00675	COG0457	Tetratricopeptide repeat
K0V03_00730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K0V03_00740	COG4086	secreted protein
K0V03_00745	COG0019	diaminopimelate decarboxylase activity
K0V03_00750	COG0697	spore germination
K0V03_00765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K0V03_00785	COG1191	sigma factor activity
K0V03_00790	COG2172	sigma factor antagonist activity
K0V03_00795	COG1366	Belongs to the anti-sigma-factor antagonist family
K0V03_00800	COG1686	Belongs to the peptidase S11 family
K0V03_00805	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K0V03_00810	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
K0V03_00815	COG4974	Belongs to the 'phage' integrase family
K0V03_00825	COG0735	belongs to the Fur family
K0V03_00830	COG1300	Membrane
K0V03_00840	COG0281	malic enzyme
K0V03_00845	COG1757	Na H antiporter
K0V03_00850	COG1027	Aspartate ammonia-lyase
K0V03_00855	COG0252	asparaginase activity
K0V03_00860	COG1396	sequence-specific DNA binding
K0V03_00865	COG1379	DNA repair
K0V03_00870	COG0494	nUDIX hydrolase
K0V03_00880	COG0667	Aldo Keto reductase
K0V03_00890	COG1073	alpha beta
K0V03_00900	COG4918	Iron-sulphur cluster biosynthesis
K0V03_00905	COG0456	acetyltransferase
K0V03_00905	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K0V03_00910	COG2329	Antibiotic biosynthesis monooxygenase
K0V03_00915	COG0456	acetyltransferase
K0V03_00925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K0V03_00935	COG2211	Major facilitator Superfamily
K0V03_00945	COG0346	lactoylglutathione lyase activity
K0V03_00950	COG1072	(Pantothenic acid kinase))
K0V03_00955	COG3048	D-serine ammonia-lyase activity
K0V03_00960	COG0300	oxidoreductase activity
K0V03_00965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K0V03_00970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K0V03_00975	COG4187	Peptidase family M20/M25/M40
K0V03_00980	COG1902	pentaerythritol trinitrate reductase activity
K0V03_00985	COG0596	Alpha beta hydrolase
K0V03_00995	COG1234	tRNA 3'-trailer cleavage
K0V03_01000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K0V03_01005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K0V03_01010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K0V03_01020	COG0706	membrane insertase activity
K0V03_01025	COG3361	conserved protein (COG2071)
K0V03_01030	COG2195	Cleaves the N-terminal amino acid of tripeptides
K0V03_01035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K0V03_01040	COG0346	lactoylglutathione lyase activity
K0V03_01050	COG1376	ErfK ybiS ycfS ynhG family protein
K0V03_01055	COG4129	membrane
K0V03_01060	COG1126	abc transporter atp-binding protein
K0V03_01065	COG0765	amino acid transport
K0V03_01070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K0V03_01080	COG1597	lipid kinase activity
K0V03_01085	COG2814	Major facilitator Superfamily
K0V03_01090	COG0789	Transcriptional regulator
K0V03_01090	COG4978	Transcriptional regulator
K0V03_01095	COG0508	dehydrogenase complex catalyzes the overall conversion of
K0V03_01100	COG0022	dehydrogenase e1 component
K0V03_01105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K0V03_01110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K0V03_01115	COG3426	butyrate kinase activity
K0V03_01120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K0V03_01125	COG0280	phosphate acetyltransferase
K0V03_01130	COG3290	protein histidine kinase activity
K0V03_01130	COG3829	transcription factor binding
K0V03_01140	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K0V03_01145	COG2079	MmgE PrpD family protein
K0V03_01150	COG0372	Belongs to the citrate synthase family
K0V03_01155	COG1960	acyl-CoA dehydrogenase activity
K0V03_01160	COG1250	3-hydroxyacyl-CoA dehydrogenase
K0V03_01165	COG0183	Belongs to the thiolase family
K0V03_01170	COG0584	glycerophosphoryl diester phosphodiesterase
K0V03_01175	COG0860	N-Acetylmuramoyl-L-alanine amidase
K0V03_01190	COG1902	pentaerythritol trinitrate reductase activity
K0V03_01195	COG0745	RESPONSE REGULATOR receiver
K0V03_01200	COG0750	zinc metalloprotease
K0V03_01205	COG0497	DNA recombination
K0V03_01210	COG1438	arginine binding
K0V03_01215	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K0V03_01220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K0V03_01225	COG0142	geranyltranstransferase activity
K0V03_01230	COG1722	exodeoxyribonuclease VII activity
K0V03_01235	COG1570	exodeoxyribonuclease VII activity
K0V03_01240	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K0V03_01245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K0V03_01250	COG1302	Protein conserved in bacteria
K0V03_01255	COG0439	Biotin carboxylase
K0V03_01260	COG0511	ligase activity, forming carbon-carbon bonds
K0V03_01300	COG3854	ATPases associated with a variety of cellular activities
K0V03_01310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K0V03_01315	COG0006	proline dipeptidase activity
K0V03_01320	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K0V03_01330	COG3872	metal-dependent enzyme
K0V03_01340	COG1752	Esterase of the alpha-beta hydrolase superfamily
K0V03_01345	COG1321	iron dependent repressor
K0V03_01350	COG0095	Lipoate-protein ligase
K0V03_01355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K0V03_01360	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K0V03_01365	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K0V03_01370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K0V03_01375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K0V03_01390	COG1396	sequence-specific DNA binding
K0V03_01400	COG0681	Belongs to the peptidase S26 family
K0V03_01425	COG4940	Competence protein ComGF
K0V03_01435	COG4970	Tfp pilus assembly protein FimT
K0V03_01440	COG4537	Required for transformation and DNA binding
K0V03_01445	COG1459	type II secretion system
K0V03_01450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K0V03_01460	COG0598	Magnesium transport protein CorA
K0V03_01465	COG1253	flavin adenine dinucleotide binding
K0V03_01470	COG1366	Belongs to the anti-sigma-factor antagonist family
K0V03_01480	COG1393	Belongs to the ArsC family
K0V03_01490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K0V03_01500	COG0011	TIGRFAM Protein of
K0V03_01510	COG2866	Carboxypeptidase
K0V03_01515	COG1368	sulfuric ester hydrolase activity
K0V03_01520	COG1940	carbohydrate kinase activity
K0V03_01525	COG4483	Protein conserved in bacteria
K0V03_01530	COG0457	Tetratricopeptide repeat
K0V03_01530	COG0705	Rhomboid family
K0V03_01540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K0V03_01550	COG0438	transferase activity, transferring glycosyl groups
K0V03_01565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K0V03_01570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K0V03_01575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K0V03_01580	COG0581	inorganic phosphate transmembrane transporter activity
K0V03_01585	COG0573	inorganic phosphate transmembrane transporter activity
K0V03_01590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K0V03_01595	COG0768	penicillin binding
K0V03_01600	COG0477	Major facilitator Superfamily
K0V03_01605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K0V03_01610	COG2839	Protein conserved in bacteria
K0V03_01615	COG5521	maltodextrose utilization protein MalA
K0V03_01620	COG1388	LysM domain
K0V03_01625	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K0V03_01630	COG4709	membrane
K0V03_01635	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
K0V03_01640	COG0735	belongs to the Fur family
K0V03_01645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K0V03_01655	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
K0V03_01660	COG0513	Belongs to the DEAD box helicase family
K0V03_01670	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K0V03_01675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K0V03_01680	COG2384	SAM-dependent methyltransferase
K0V03_01685	COG2010	Cytochrome c
K0V03_01690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K0V03_01695	COG0358	DNA primase activity
K0V03_01700	COG1671	Belongs to the UPF0178 family
K0V03_01705	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
K0V03_01710	COG0517	IMP dehydrogenase activity
K0V03_01715	COG0751	glycine-tRNA ligase activity
K0V03_01720	COG0752	glycyl-tRNA synthetase alpha subunit
K0V03_01725	COG1381	Involved in DNA repair and RecF pathway recombination
K0V03_01735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K0V03_01740	COG0295	cytidine deaminase activity
K0V03_01745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K0V03_01750	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K0V03_01755	COG1480	7TM receptor with intracellular HD hydrolase
K0V03_01760	COG1702	phosphate starvation-inducible protein PhoH
K0V03_01765	COG0561	phosphatase activity
K0V03_01780	COG4864	UPF0365 protein
K0V03_01785	COG1030	water channel activity
K0V03_01790	COG1610	YqeY-like protein
K0V03_01800	COG1283	sodium-dependent phosphate transmembrane transporter activity
K0V03_01805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K0V03_01810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K0V03_01815	COG2264	protein methyltransferase activity
K0V03_01820	COG0484	heat shock protein binding
K0V03_01825	COG0443	Heat shock 70 kDa protein
K0V03_01830	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K0V03_01835	COG1420	regulation of RNA biosynthetic process
K0V03_01840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K0V03_01845	COG0481	GTPase activity
K0V03_01855	COG0860	N-Acetylmuramoyl-L-alanine amidase
K0V03_01860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
K0V03_01865	COG0268	Binds directly to 16S ribosomal RNA
K0V03_01870	COG1466	dna polymerase III delta subunit
K0V03_01890	COG2131	deaminase
K0V03_01895	COG1596	polysaccharide export
K0V03_01895	COG1555	photosystem II stabilization
K0V03_01900	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K0V03_01905	COG2226	methyltransferase
K0V03_01910	COG0799	negative regulation of ribosome biogenesis
K0V03_01915	COG1713	HD superfamily hydrolase involved in NAD metabolism
K0V03_01920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K0V03_01925	COG1534	Rna-binding protein
K0V03_01930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K0V03_01935	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K0V03_01940	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K0V03_01950	COG2755	lipolytic protein G-D-S-L family
K0V03_01955	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_01955	COG5632	N-Acetylmuramoyl-L-alanine amidase
K0V03_01960	COG0398	Pfam SNARE associated Golgi protein
K0V03_01965	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K0V03_01975	COG3209	COG3209 Rhs family protein
K0V03_01985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K0V03_01990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K0V03_01995	COG0798	PFAM Bile acid sodium symporter
K0V03_02000	COG0346	lactoylglutathione lyase activity
K0V03_02005	COG0640	Transcriptional regulator
K0V03_02010	COG3403	YqcI/YcgG family
K0V03_02030	COG5444	nuclease activity
K0V03_02055	COG5632	N-Acetylmuramoyl-L-alanine amidase
K0V03_02055	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_02060	COG4824	toxin secretion phage lysis holin
K0V03_02090	COG3778	Protein conserved in bacteria
K0V03_02095	COG3299	homolog of phage Mu protein gp47
K0V03_02100	COG3628	GPW Gp25 family protein
K0V03_02110	COG4193	domain, Protein
K0V03_02115	COG1652	LysM domain
K0V03_02120	COG3953	SLT domain
K0V03_02120	COG5280	Phage tail tape measure protein TP901
K0V03_02180	COG4653	Phage capsid family
K0V03_02185	COG0338	D12 class N6 adenine-specific DNA methyltransferase
K0V03_02200	COG2369	cell adhesion
K0V03_02205	COG5518	Phage portal protein
K0V03_02210	COG1783	phage Terminase large subunit
K0V03_02215	COG5484	DNA packaging
K0V03_02225	COG3677	Transposase
K0V03_02240	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
K0V03_02250	COG1484	DNA-dependent DNA replication
K0V03_02255	COG3935	DnaD domain protein
K0V03_02260	COG3723	Recombinational DNA repair protein, rece pathway
K0V03_02265	COG5377	YqaJ viral recombinase family
K0V03_02295	COG1476	TRANSCRIPTIONal
K0V03_02300	COG3620	sequence-specific DNA binding
K0V03_02310	COG0563	adenylate kinase activity
K0V03_02315	COG2856	Zn peptidase
K0V03_02330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K0V03_02340	COG3223	Belongs to the PsiE family
K0V03_02345	COG0642	Histidine kinase
K0V03_02345	COG5002	protein histidine kinase activity
K0V03_02350	COG0745	RESPONSE REGULATOR receiver
K0V03_02355	COG2311	Membrane
K0V03_02365	COG0454	-acetyltransferase
K0V03_02370	COG2249	NAD(P)H dehydrogenase (quinone) activity
K0V03_02380	COG0730	response to heat
K0V03_02385	COG0425	Belongs to the sulfur carrier protein TusA family
K0V03_02390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K0V03_02390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K0V03_02400	COG0425	Belongs to the sulfur carrier protein TusA family
K0V03_02400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K0V03_02405	COG2210	Belongs to the sulfur carrier protein TusA family
K0V03_02410	COG1937	Protein conserved in bacteria
K0V03_02415	COG0662	Cupin 2, conserved barrel domain protein
K0V03_02430	COG2814	Major facilitator Superfamily
K0V03_02435	COG0456	acetyltransferase
K0V03_02440	COG1253	flavin adenine dinucleotide binding
K0V03_02450	COG0697	spore germination
K0V03_02455	COG0583	DNA-binding transcription factor activity
K0V03_02460	COG2072	flavoprotein involved in K transport
K0V03_02465	COG1230	cation diffusion facilitator family transporter
K0V03_02475	COG1114	Component of the transport system for branched-chain amino acids
K0V03_02480	COG1687	branched-chain amino acid
K0V03_02485	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K0V03_02490	COG1522	sequence-specific DNA binding
K0V03_02495	COG2732	(Barnase) inhibitor
K0V03_02500	COG2124	cytochrome p450
K0V03_02510	COG1335	isochorismatase
K0V03_02525	COG2318	DinB family
K0V03_02535	COG2070	2-Nitropropane dioxygenase
K0V03_02540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K0V03_02550	COG2186	Transcriptional regulator
K0V03_02565	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_02570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K0V03_02575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K0V03_02580	COG0477	Major facilitator Superfamily
K0V03_02585	COG1846	Transcriptional regulator
K0V03_02590	COG3443	Belongs to the bacterial solute-binding protein 9 family
K0V03_02595	COG1595	DNA-templated transcription, initiation
K0V03_02600	COG0667	Aldo Keto reductase
K0V03_02605	COG2851	Citrate transporter
K0V03_02610	COG0583	DNA-binding transcription factor activity
K0V03_02615	COG2828	Protein conserved in bacteria
K0V03_02620	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_02625	COG5566	PFAM Mor transcription activator
K0V03_02630	COG0596	Alpha beta hydrolase
K0V03_02635	COG4991	sh3 domain protein
K0V03_02640	COG4991	sh3 domain protein
K0V03_02650	COG0346	lactoylglutathione lyase activity
K0V03_02660	COG5577	PFAM Coat F domain
K0V03_02665	COG1063	alcohol dehydrogenase
K0V03_02675	COG5577	PFAM Coat F domain
K0V03_02680	COG0789	Transcriptional regulator
K0V03_02690	COG1064	alcohol dehydrogenase
K0V03_02695	COG0693	protein deglycase activity
K0V03_02700	COG1621	beta-fructofuranosidase activity
K0V03_02705	COG3716	PTS system mannose fructose sorbose family IID component
K0V03_02710	COG3715	PTS system
K0V03_02715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K0V03_02720	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
K0V03_02725	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K0V03_02725	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K0V03_02735	COG1113	amino acid transport
K0V03_02740	COG1280	lysine exporter protein (LysE YggA)
K0V03_02745	COG1378	Sugar-specific transcriptional regulator TrmB
K0V03_02750	COG1595	DNA-templated transcription, initiation
K0V03_02760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K0V03_02760	COG2755	lipolytic protein G-D-S-L family
K0V03_02770	COG2124	cytochrome p450
K0V03_02770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K0V03_02775	COG1309	transcriptional regulator
K0V03_02780	COG2226	methyltransferase
K0V03_02795	COG2116	formate transmembrane transporter activity
K0V03_02800	COG5609	conserved protein (DUF2294)
K0V03_02805	COG3383	formate dehydrogenase (NAD+) activity
K0V03_02810	COG2427	Protein of unknown function (DUF1641)
K0V03_02820	COG0626	cystathionine gamma-synthase activity
K0V03_02825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K0V03_02830	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K0V03_02835	COG2226	methyltransferase
K0V03_02850	COG0768	penicillin binding
K0V03_02855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K0V03_02860	COG0572	uridine kinase
K0V03_02865	COG0826	peptidase U32
K0V03_02870	COG0826	peptidase U32
K0V03_02875	COG4122	O-methyltransferase activity
K0V03_02880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K0V03_02885	COG3906	Belongs to the UPF0473 family
K0V03_02890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K0V03_02895	COG4472	Bacterial protein of unknown function (DUF965)
K0V03_02900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K0V03_02905	COG0628	permease
K0V03_02910	COG1126	abc transporter atp-binding protein
K0V03_02915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K0V03_02920	COG0765	amino acid transport
K0V03_02925	COG0765	amino acid transport
K0V03_02940	COG3881	PFAM PRC-barrel domain
K0V03_02945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K0V03_02950	COG0457	Tetratricopeptide repeat
K0V03_02955	COG0482	sulfurtransferase activity
K0V03_02960	COG1104	cysteine desulfurase activity
K0V03_02965	COG1959	2 iron, 2 sulfur cluster binding
K0V03_02970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K0V03_02975	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K0V03_02985	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K0V03_02990	COG0124	histidyl-tRNA synthetase
K0V03_03000	COG0860	N-Acetylmuramoyl-L-alanine amidase
K0V03_03000	COG3103	Sh3 type 3 domain protein
K0V03_03000	COG4991	sh3 domain protein
K0V03_03005	COG1490	D-aminoacyl-tRNA deacylase activity
K0V03_03010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K0V03_03015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K0V03_03020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K0V03_03020	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K0V03_03025	COG5416	Lipopolysaccharide assembly protein A domain
K0V03_03030	COG0490	domain, Protein
K0V03_03035	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K0V03_03035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K0V03_03045	COG2244	polysaccharide biosynthetic process
K0V03_03050	COG2323	membrane
K0V03_03060	COG1862	Preprotein translocase
K0V03_03065	COG0343	queuine tRNA-ribosyltransferase activity
K0V03_03070	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K0V03_03080	COG2255	four-way junction helicase activity
K0V03_03085	COG0632	four-way junction helicase activity
K0V03_03095	COG2814	Major facilitator Superfamily
K0V03_03100	COG0673	inositol 2-dehydrogenase activity
K0V03_03105	COG2112	serine threonine protein kinase
K0V03_03125	COG1115	amino acid carrier protein
K0V03_03130	COG0217	transcriptional regulatory protein
K0V03_03140	COG1388	LysM domain
K0V03_03145	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K0V03_03150	COG0157	Belongs to the NadC ModD family
K0V03_03155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K0V03_03160	COG1104	cysteine desulfurase activity
K0V03_03165	COG1827	regulation of RNA biosynthetic process
K0V03_03170	COG0077	Prephenate dehydratase
K0V03_03175	COG4492	Belongs to the UPF0735 family
K0V03_03180	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K0V03_03185	COG3290	protein histidine kinase activity
K0V03_03195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K0V03_03200	COG2868	ribosomal protein
K0V03_03205	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K0V03_03210	COG1994	Peptidase M50
K0V03_03215	COG0739	heme binding
K0V03_03220	COG2894	cell division
K0V03_03225	COG0850	regulation of cytokinetic process
K0V03_03230	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
K0V03_03240	COG1077	Cell shape determining protein MreB Mrl
K0V03_03280	COG5444	nuclease activity
K0V03_03290	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_03290	COG5632	N-Acetylmuramoyl-L-alanine amidase
K0V03_03290	COG1388	LysM domain
K0V03_03325	COG1705	Flagellar rod assembly protein muramidase FlgJ
K0V03_03335	COG5280	Phage tail tape measure protein TP901
K0V03_03335	COG3953	SLT domain
K0V03_03510	COG1396	sequence-specific DNA binding
K0V03_03525	COG2003	Belongs to the UPF0758 family
K0V03_03530	COG0424	maF-like protein
K0V03_03540	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K0V03_03545	COG0285	dihydrofolate synthase activity
K0V03_03550	COG0525	valine-tRNA ligase activity
K0V03_03560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K0V03_03565	COG1388	LysM domain
K0V03_03570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K0V03_03575	COG0113	porphobilinogen synthase activity
K0V03_03580	COG1587	Uroporphyrinogen-III synthase
K0V03_03585	COG0181	hydroxymethylbilane synthase activity
K0V03_03590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K0V03_03595	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K0V03_03605	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K0V03_03610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K0V03_03615	COG0470	DNA polymerase III
K0V03_03615	COG1067	ATP-dependent peptidase activity
K0V03_03620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K0V03_03625	COG0544	peptidyl-prolyl cis-trans isomerase activity
K0V03_03630	COG0457	Tetratricopeptide repeat
K0V03_03630	COG1477	protein flavinylation
K0V03_03635	COG0066	3-isopropylmalate dehydratase activity
K0V03_03640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K0V03_03645	COG0473	3-isopropylmalate dehydrogenase activity
K0V03_03650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K0V03_03655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K0V03_03660	COG0440	acetolactate synthase activity
K0V03_03665	COG0028	Belongs to the TPP enzyme family
K0V03_03680	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
K0V03_03690	COG0622	Phosphoesterase
K0V03_03695	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K0V03_03700	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K0V03_03705	COG5401	PFAM Sporulation and spore germination
K0V03_03710	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K0V03_03715	COG1846	Transcriptional regulator
K0V03_03720	COG2197	response regulator
K0V03_03725	COG0824	Thioesterase
K0V03_03730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K0V03_03735	COG1053	succinate dehydrogenase
K0V03_03740	COG2009	succinate dehydrogenase
K0V03_03745	COG1719	4-vinyl reductase, 4VR
K0V03_03750	COG0527	aspartate kinase activity
K0V03_03755	COG0322	excinuclease ABC activity
K0V03_03760	COG3118	belongs to the thioredoxin family
K0V03_03765	COG3534	alpha-L-arabinofuranosidase
K0V03_03770	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K0V03_03775	COG2086	electron transfer activity
K0V03_03780	COG1024	Enoyl-CoA hydratase
K0V03_03785	COG1309	transcriptional regulator
K0V03_03790	COG0318	PFAM AMP-dependent synthetase and ligase
K0V03_03795	COG3766	membrane
K0V03_03800	COG1193	negative regulation of DNA recombination
K0V03_03805	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K0V03_03805	COG1796	DNA polymerase
K0V03_03810	COG1286	toxin biosynthetic process
K0V03_03815	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
K0V03_03820	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K0V03_03825	COG0072	phenylalanine-tRNA ligase activity
K0V03_03825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K0V03_03830	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K0V03_03840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K0V03_03850	COG3835	regulator
K0V03_03855	COG0277	FAD linked oxidase domain protein
K0V03_03860	COG0247	lactate metabolic process
K0V03_03865	COG0346	lactoylglutathione lyase activity
K0V03_03870	COG1966	Carbon starvation protein
K0V03_03875	COG3534	alpha-L-arabinofuranosidase
K0V03_03880	COG0395	ABC-type sugar transport system, permease component
K0V03_03885	COG1175	transmembrane transport
K0V03_03890	COG1653	transport
K0V03_03895	COG0371	Dehydrogenase
K0V03_03900	COG0647	UMP catabolic process
K0V03_03905	COG0235	Class ii aldolase
K0V03_03910	COG1069	ribulokinase activity
K0V03_03915	COG2160	L-arabinose isomerase activity
K0V03_03920	COG3507	Belongs to the glycosyl hydrolase 43 family
K0V03_03925	COG1363	Peptidase, m42
K0V03_03935	COG3326	Membrane
K0V03_03940	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K0V03_03945	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K0V03_03950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K0V03_03960	COG1346	cytolysis
K0V03_03965	COG1380	Effector of murein hydrolase LrgA
K0V03_03970	COG3279	Response regulator of the LytR AlgR family
K0V03_03975	COG3275	phosphorelay sensor kinase activity
K0V03_03980	COG1011	Hydrolase
K0V03_03985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K0V03_03995	COG0398	Pfam SNARE associated Golgi protein
K0V03_04000	COG1484	DNA-dependent DNA replication
K0V03_04005	COG3611	Membrane attachment protein
K0V03_04010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K0V03_04015	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K0V03_04020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K0V03_04025	COG1733	regulation of RNA biosynthetic process
K0V03_04030	COG2814	Major facilitator Superfamily
K0V03_04035	COG0656	L-ascorbic acid biosynthetic process
K0V03_04040	COG0237	dephospho-CoA kinase activity
K0V03_04045	COG1971	Probably functions as a manganese efflux pump
K0V03_04050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K0V03_04055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K0V03_04055	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K0V03_04060	COG5002	protein histidine kinase activity
K0V03_04065	COG0745	RESPONSE REGULATOR receiver
K0V03_04070	COG0039	L-malate dehydrogenase activity
K0V03_04075	COG0538	isocitrate dehydrogenase activity
K0V03_04080	COG0372	Belongs to the citrate synthase family
K0V03_04085	COG2707	UPF0756 membrane protein
K0V03_04090	COG0628	permease
K0V03_04095	COG3030	protein affecting phage T7 exclusion by the F plasmid
K0V03_04100	COG0469	pyruvate kinase activity
K0V03_04105	COG0205	6-phosphofructokinase activity
K0V03_04110	COG0825	malonyl-CoA metabolic process
K0V03_04115	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K0V03_04120	COG0281	malic enzyme
K0V03_04125	COG0587	DNA-directed DNA polymerase activity
K0V03_04145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K0V03_04155	COG4109	DRTGG domain
K0V03_04160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K0V03_04165	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_04170	COG0165	Argininosuccinate lyase
K0V03_04175	COG0137	argininosuccinate synthase activity
K0V03_04180	COG0521	Mo-molybdopterin cofactor biosynthetic process
K0V03_04185	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K0V03_04195	COG0827	DNA restriction-modification system
K0V03_04200	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K0V03_04205	COG3874	Sporulation protein YtfJ
K0V03_04215	COG1714	RDD family
K0V03_04220	COG0616	signal peptide processing
K0V03_04225	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K0V03_04230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K0V03_04235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K0V03_04245	COG0301	tRNA thio-modification
K0V03_04250	COG1104	cysteine desulfurase activity
K0V03_04255	COG1114	Component of the transport system for branched-chain amino acids
K0V03_04260	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
K0V03_04265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K0V03_04270	COG1309	transcriptional regulator
K0V03_04275	COG1956	GAF domain-containing protein
K0V03_04280	COG2199	diguanylate cyclase activity
K0V03_04280	COG2203	Gaf domain
K0V03_04285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K0V03_04290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K0V03_04295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K0V03_04300	COG0454	-acetyltransferase
K0V03_04305	COG0517	IMP dehydrogenase activity
K0V03_04310	COG0123	including yeast histone deacetylase and acetoin utilization protein
K0V03_04315	COG1360	Flagellar Motor Protein
K0V03_04320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K0V03_04325	COG1609	Transcriptional regulator
K0V03_04330	COG1605	Chorismate mutase
K0V03_04330	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K0V03_04335	COG3118	belongs to the thioredoxin family
K0V03_04340	COG4980	gas vesicle protein
K0V03_04345	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
K0V03_04350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K0V03_04355	COG1674	ftsk spoiiie
K0V03_04360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K0V03_04365	COG4848	Belongs to the UPF0354 family
K0V03_04370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K0V03_04385	COG1363	Peptidase, m42
K0V03_04390	COG5584	Small secreted protein
K0V03_04395	COG0281	malic enzyme
K0V03_04400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K0V03_04405	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K0V03_04415	COG0510	thiamine kinase activity
K0V03_04420	COG1523	belongs to the glycosyl hydrolase 13 family
K0V03_04425	COG1597	lipid kinase activity
K0V03_04435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K0V03_04440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K0V03_04445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K0V03_04450	COG2252	PERMEase
K0V03_04455	COG4473	ABC transporter
K0V03_04460	COG1131	(ABC) transporter
K0V03_04465	COG1349	DNA-binding transcription factor activity
K0V03_04470	COG1187	pseudouridine synthase activity
K0V03_04475	COG2244	polysaccharide biosynthetic process
K0V03_04480	COG2081	HI0933 family
K0V03_04485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K0V03_04495	COG5578	integral membrane protein
K0V03_04500	COG0673	inositol 2-dehydrogenase activity
K0V03_04505	COG1653	transport
K0V03_04510	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K0V03_04515	COG4209	transmembrane transport
K0V03_04520	COG2207	Transcriptional regulator
K0V03_04525	COG1653	transport
K0V03_04530	COG0395	ABC-type sugar transport system, permease component
K0V03_04535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K0V03_04540	COG2124	cytochrome p450
K0V03_04545	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K0V03_04555	COG0156	8-amino-7-oxononanoate synthase activity
K0V03_04560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K0V03_04570	COG1073	alpha beta
K0V03_04575	COG1609	Transcriptional regulator
K0V03_04580	COG1653	transport
K0V03_04585	COG1175	transmembrane transport
K0V03_04590	COG0395	ABC-type sugar transport system, permease component
K0V03_04595	COG1486	melibiose metabolic process
K0V03_04600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K0V03_04605	COG0495	leucyl-tRNA aminoacylation
K0V03_04615	COG1366	Belongs to the anti-sigma-factor antagonist family
K0V03_04615	COG2202	Pas domain
K0V03_04620	COG2814	Major facilitator Superfamily
K0V03_04625	COG2433	Pfam Transposase IS66
K0V03_04630	COG0577	efflux transmembrane transporter activity
K0V03_04635	COG1136	(ABC) transporter
K0V03_04640	COG2205	protein histidine kinase activity
K0V03_04645	COG0745	RESPONSE REGULATOR receiver
K0V03_04650	COG0577	efflux transmembrane transporter activity
K0V03_04655	COG1136	(ABC) transporter
K0V03_04670	COG1131	(ABC) transporter
K0V03_04675	COG1725	Transcriptional regulator
K0V03_04690	COG1242	4 iron, 4 sulfur cluster binding
K0V03_04695	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K0V03_04705	COG2267	carboxylic ester hydrolase activity
K0V03_04710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K0V03_04715	COG1113	amino acid transport
K0V03_04720	COG0367	asparagine synthase
K0V03_04725	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K0V03_04730	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
K0V03_04740	COG1506	peptidase
K0V03_04745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K0V03_04750	COG1116	anion transmembrane transporter activity
K0V03_04755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K0V03_04760	COG0494	nUDIX hydrolase
K0V03_04765	COG4824	toxin secretion phage lysis holin
K0V03_04770	COG0783	Belongs to the Dps family
K0V03_04785	COG1854	S-ribosylhomocysteine lyase activity
K0V03_04790	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
K0V03_04795	COG0288	reversible hydration of carbon dioxide
K0V03_04800	COG0254	rRNA binding
K0V03_04805	COG1271	oxidase subunit
K0V03_04810	COG1294	oxidase, subunit
K0V03_04820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K0V03_04825	COG1321	iron dependent repressor
K0V03_04825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K0V03_04830	COG1121	(ABC) transporter
K0V03_04835	COG0803	Belongs to the bacterial solute-binding protein 9 family
K0V03_04840	COG4948	Mandelate Racemase Muconate Lactonizing
K0V03_04845	COG0318	PFAM AMP-dependent synthetase and ligase
K0V03_04850	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K0V03_04855	COG0596	Alpha beta hydrolase
K0V03_04860	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
K0V03_04865	COG1169	isochorismate synthase
K0V03_04870	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K0V03_04875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K0V03_04880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K0V03_04885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K0V03_04890	COG0438	transferase activity, transferring glycosyl groups
K0V03_04900	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K0V03_04905	COG0438	transferase activity, transferring glycosyl groups
K0V03_04910	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K0V03_04915	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
K0V03_04920	COG0058	SHG alpha-glucan phosphorylase activity
K0V03_04925	COG0297	glycogen (starch) synthase activity
K0V03_04930	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K0V03_04935	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K0V03_04940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K0V03_05065	COG3859	Proton-coupled thiamine transporter YuaJ
K0V03_05070	COG1247	-acetyltransferase
K0V03_05075	COG2268	Band 7 protein
K0V03_05080	COG1585	Membrane protein implicated in regulation of membrane protease activity
K0V03_05085	COG2318	DinB family
K0V03_05095	COG1454	alcohol dehydrogenase
K0V03_05100	COG1012	belongs to the aldehyde dehydrogenase family
K0V03_05105	COG1510	regulation of RNA biosynthetic process
K0V03_05115	COG0569	domain protein
K0V03_05120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K0V03_05125	COG4682	membrane
K0V03_05130	COG1705	Flagellar rod assembly protein muramidase FlgJ
K0V03_05135	COG0477	Major facilitator Superfamily
K0V03_05140	COG5553	Cysteine dioxygenase type I
K0V03_05150	COG1968	undecaprenyl-diphosphatase activity
K0V03_05155	COG0628	permease
K0V03_05160	COG0673	inositol 2-dehydrogenase activity
K0V03_05165	COG4806	L-rhamnose isomerase
K0V03_05170	COG3254	rhamnose metabolic process
K0V03_05175	COG1070	Carbohydrate kinase
K0V03_05180	COG1349	DNA-binding transcription factor activity
K0V03_05185	COG3347	Dehydrogenase
K0V03_05185	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_05190	COG0840	transmembrane signaling receptor activity
K0V03_05195	COG0840	transmembrane signaling receptor activity
K0V03_05200	COG0840	transmembrane signaling receptor activity
K0V03_05205	COG0840	transmembrane signaling receptor activity
K0V03_05220	COG0432	Pfam Uncharacterised protein family UPF0047
K0V03_05230	COG0366	Alpha amylase catalytic
K0V03_05235	COG1253	flavin adenine dinucleotide binding
K0V03_05240	COG2738	Putative neutral zinc metallopeptidase
K0V03_05255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K0V03_05270	COG0166	Belongs to the GPI family
K0V03_05275	COG1979	alcohol dehydrogenase
K0V03_05280	COG1979	alcohol dehydrogenase
K0V03_05285	COG2155	Conserved Protein
K0V03_05290	COG1098	S1 RNA binding domain
K0V03_05295	COG0436	Aminotransferase
K0V03_05300	COG1522	sequence-specific DNA binding
K0V03_05305	COG2267	carboxylic ester hydrolase activity
K0V03_05315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K0V03_05320	COG2205	protein histidine kinase activity
K0V03_05330	COG5018	Exonuclease
K0V03_05335	COG2814	Major facilitator Superfamily
K0V03_05340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K0V03_05345	COG3011	Protein conserved in bacteria
K0V03_05355	COG3290	protein histidine kinase activity
K0V03_05360	COG4565	transcriptional regulatory protein
K0V03_05365	COG1744	ABC transporter substrate-binding protein PnrA-like
K0V03_05370	COG3845	ABC transporter
K0V03_05375	COG4603	Belongs to the binding-protein-dependent transport system permease family
K0V03_05380	COG1079	Belongs to the binding-protein-dependent transport system permease family
K0V03_05385	COG3493	citrate carrier protein
K0V03_05395	COG2111	Na H antiporter
K0V03_05395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K0V03_05400	COG2111	Na H antiporter
K0V03_05405	COG1006	Multisubunit Na H antiporter MnhC subunit
K0V03_05410	COG0651	ATP synthesis coupled electron transport
K0V03_05415	COG1863	multisubunit Na H antiporter MnhE subunit
K0V03_05420	COG2212	antiporter activity
K0V03_05425	COG1320	monovalent cation:proton antiporter activity
K0V03_05430	COG2050	protein possibly involved in aromatic compounds catabolism
K0V03_05435	COG2197	response regulator
K0V03_05440	COG4585	Histidine kinase
K0V03_05450	COG0142	geranyltranstransferase activity
K0V03_05470	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
K0V03_05475	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K0V03_05480	COG1335	isochorismatase
K0V03_05485	COG5506	Protein of unknown function (DUF1694)
K0V03_05500	COG0628	permease
K0V03_05515	COG1418	mRNA catabolic process
K0V03_05520	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_05530	COG1511	domain protein
K0V03_05535	COG1674	ftsk spoiiie
K0V03_05535	COG0433	COG0433 Predicted ATPase
K0V03_05540	COG4499	WXG100 protein secretion system (Wss), protein YukC
K0V03_05545	COG5417	Belongs to the EsaB family
K0V03_05550	COG4842	Belongs to the WXG100 family
K0V03_05555	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
K0V03_05555	COG2508	Transcriptional regulator
K0V03_05560	COG0686	Belongs to the AlaDH PNT family
K0V03_05565	COG5634	Uncharacterized conserved protein (DUF2278)
K0V03_05570	COG3251	PFAM MbtH domain protein
K0V03_05575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K0V03_05580	COG3433	isochorismatase activity
K0V03_05580	COG1535	isochorismatase
K0V03_05585	COG1021	2,3-dihydroxybenzoate-AMP ligase
K0V03_05590	COG1169	isochorismate synthase
K0V03_05595	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_05600	COG2819	hydrolase of the alpha beta superfamily
K0V03_05605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K0V03_05610	COG1268	BioY protein
K0V03_05615	COG2056	Na+-H+ antiporter family
K0V03_05620	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K0V03_05625	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
K0V03_05630	COG3584	3D domain protein
K0V03_05645	COG1252	NADH dehydrogenase
K0V03_05650	COG0492	ferredoxin-NADP+ reductase activity
K0V03_05660	COG0516	GMP reductase activity
K0V03_05665	COG2808	Putative FMN-binding domain
K0V03_05670	COG0456	acetyltransferase
K0V03_05675	COG0316	Belongs to the HesB IscA family
K0V03_05680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K0V03_05685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K0V03_05690	COG4844	belongs to the
K0V03_05695	COG1252	NADH dehydrogenase
K0V03_05700	COG4837	Protein of unknown function (DUF1462)
K0V03_05705	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K0V03_05710	COG0823	Involved in the tonB-independent uptake of proteins
K0V03_05710	COG1506	peptidase
K0V03_05710	COG4946	Tricorn protease homolog
K0V03_05715	COG0083	homoserine kinase activity
K0V03_05720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K0V03_05725	COG0460	homoserine dehydrogenase
K0V03_05730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K0V03_05735	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K0V03_05740	COG0647	UMP catabolic process
K0V03_05745	COG2445	Protein of unknown function DUF86
K0V03_05750	COG4470	Protein conserved in bacteria
K0V03_05760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K0V03_05765	COG0739	heme binding
K0V03_05775	COG3377	Domain of unknown function (DUF1805)
K0V03_05780	COG0737	Belongs to the 5'-nucleotidase family
K0V03_05785	COG0730	response to heat
K0V03_05790	COG1801	Protein of unknown function DUF72
K0V03_05800	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K0V03_05805	COG2508	Transcriptional regulator
K0V03_05810	COG2233	PERMEase
K0V03_05815	COG2233	PERMEase
K0V03_05820	COG3195	allantoin biosynthetic process
K0V03_05820	COG3648	Uricase
K0V03_05825	COG2351	hydroxyisourate hydrolase activity
K0V03_05835	COG2080	2 iron, 2 sulfur cluster binding
K0V03_05840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K0V03_05845	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K0V03_05850	COG2068	MobA-Related Protein
K0V03_05855	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
K0V03_05860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K0V03_05865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K0V03_05875	COG2356	endonuclease I
K0V03_05880	COG3842	ATPase activity
K0V03_05885	COG2188	Transcriptional regulator
K0V03_05890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K0V03_05895	COG0395	ABC-type sugar transport system, permease component
K0V03_05900	COG1175	transmembrane transport
K0V03_05905	COG1653	transport
K0V03_05910	COG2222	sugar isomerase
K0V03_05915	COG0322	excinuclease ABC activity
K0V03_05920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K0V03_05935	COG0346	lactoylglutathione lyase activity
K0V03_05940	COG0640	Transcriptional regulator
K0V03_05945	COG0719	Fe-S assembly protein
K0V03_05950	COG0822	iron-sulfur transferase activity
K0V03_05955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K0V03_05960	COG0719	Fe-S assembly protein
K0V03_05965	COG0396	ATPase activity
K0V03_05975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K0V03_05980	COG1464	Belongs to the NlpA lipoprotein family
K0V03_05985	COG2011	ABC-type metal ion transport system permease component
K0V03_05990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K0V03_06000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K0V03_06005	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K0V03_06015	COG0509	glycine decarboxylation via glycine cleavage system
K0V03_06020	COG1393	Belongs to the ArsC family
K0V03_06025	COG1960	acyl-CoA dehydrogenase activity
K0V03_06030	COG0183	Belongs to the thiolase family
K0V03_06035	COG1250	3-hydroxyacyl-CoA dehydrogenase
K0V03_06035	COG1024	Enoyl-CoA hydratase
K0V03_06045	COG0506	proline dehydrogenase activity
K0V03_06055	COG5577	PFAM Coat F domain
K0V03_06060	COG1846	Transcriptional regulator
K0V03_06065	COG0477	Major facilitator Superfamily
K0V03_06070	COG1942	4-Oxalocrotonate Tautomerase
K0V03_06075	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_06080	COG0583	DNA-binding transcription factor activity
K0V03_06090	COG1120	ATPase activity
K0V03_06105	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_06110	COG0783	Belongs to the Dps family
K0V03_06115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K0V03_06120	COG0745	RESPONSE REGULATOR receiver
K0V03_06125	COG2205	protein histidine kinase activity
K0V03_06125	COG2770	Histidine kinase
K0V03_06135	COG1309	transcriptional regulator
K0V03_06140	COG0114	fumarate hydratase activity
K0V03_06150	COG0697	spore germination
K0V03_06155	COG0814	amino acid
K0V03_06165	COG2197	response regulator
K0V03_06170	COG4585	Histidine kinase
K0V03_06175	COG4758	membrane
K0V03_06180	COG3595	metallopeptidase activity
K0V03_06185	COG1842	Phage shock protein A
K0V03_06190	COG4758	membrane
K0V03_06195	COG2814	Major facilitator Superfamily
K0V03_06200	COG2096	Adenosyltransferase
K0V03_06205	COG1120	ATPase activity
K0V03_06210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K0V03_06215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K0V03_06220	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_06225	COG3386	PFAM SMP-30 Gluconolaconase
K0V03_06230	COG2205	protein histidine kinase activity
K0V03_06235	COG0745	RESPONSE REGULATOR receiver
K0V03_06245	COG1191	sigma factor activity
K0V03_06255	COG2140	Oxalate decarboxylase
K0V03_06265	COG0577	efflux transmembrane transporter activity
K0V03_06270	COG1136	(ABC) transporter
K0V03_06275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K0V03_06280	COG1120	ATPase activity
K0V03_06285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K0V03_06290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K0V03_06295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K0V03_06300	COG0531	amino acid
K0V03_06310	COG1988	membrane-bound metal-dependent
K0V03_06315	COG1368	sulfuric ester hydrolase activity
K0V03_06320	COG1910	domain protein
K0V03_06325	COG0725	ABC transporter, periplasmic molybdate-binding protein
K0V03_06330	COG4149	molybdate abc transporter
K0V03_06335	COG0656	L-ascorbic acid biosynthetic process
K0V03_06345	COG0025	NhaP-type Na H and K H
K0V03_06350	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K0V03_06355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K0V03_06360	COG3973	AAA domain
K0V03_06370	COG2860	membrane
K0V03_06375	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
K0V03_06380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K0V03_06385	COG2217	Heavy metal translocating P-type atpase
K0V03_06390	COG2217	Heavy metal translocating P-type atpase
K0V03_06395	COG2608	mercury ion transmembrane transporter activity
K0V03_06400	COG1937	Protein conserved in bacteria
K0V03_06405	COG0673	inositol 2-dehydrogenase activity
K0V03_06410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K0V03_06415	COG1289	transmembrane transporter activity
K0V03_06425	COG2076	Multidrug Resistance protein
K0V03_06430	COG1309	transcriptional regulator
K0V03_06435	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_06445	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K0V03_06450	COG0557	exoribonuclease II activity
K0V03_06455	COG1647	Serine aminopeptidase, S33
K0V03_06460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K0V03_06465	COG0596	Alpha beta hydrolase
K0V03_06470	COG1476	TRANSCRIPTIONal
K0V03_06475	COG1396	sequence-specific DNA binding
K0V03_06480	COG1396	sequence-specific DNA binding
K0V03_06485	COG1733	regulation of RNA biosynthetic process
K0V03_06490	COG0840	transmembrane signaling receptor activity
K0V03_06515	COG1131	(ABC) transporter
K0V03_06545	COG1174	glycine betaine transport
K0V03_06550	COG1732	Glycine betaine
K0V03_06555	COG1174	glycine betaine transport
K0V03_06560	COG0517	IMP dehydrogenase activity
K0V03_06560	COG1125	glycine betaine transport
K0V03_06565	COG1510	regulation of RNA biosynthetic process
K0V03_06570	COG1174	glycine betaine transport
K0V03_06575	COG1732	Glycine betaine
K0V03_06580	COG1174	glycine betaine transport
K0V03_06585	COG0517	IMP dehydrogenase activity
K0V03_06585	COG1125	glycine betaine transport
K0V03_06590	COG1510	regulation of RNA biosynthetic process
K0V03_06595	COG2095	MarC family integral membrane protein
K0V03_06605	COG3064	Membrane
K0V03_06610	COG4640	response to antibiotic
K0V03_06615	COG0456	acetyltransferase
K0V03_06620	COG0148	phosphopyruvate hydratase activity
K0V03_06625	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K0V03_06630	COG0149	triose-phosphate isomerase activity
K0V03_06635	COG0126	phosphoglycerate kinase activity
K0V03_06640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K0V03_06645	COG2390	Transcriptional regulator
K0V03_06650	COG2814	Major facilitator Superfamily
K0V03_06655	COG1609	Transcriptional regulator
K0V03_06660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K0V03_06665	COG0583	DNA-binding transcription factor activity
K0V03_06670	COG0697	spore germination
K0V03_06675	COG1113	amino acid transport
K0V03_06680	COG3858	chitin binding
K0V03_06685	COG1556	Lactate utilization protein
K0V03_06690	COG1139	Iron-sulfur cluster binding protein
K0V03_06695	COG0247	lactate metabolic process
K0V03_06700	COG2197	response regulator
K0V03_06705	COG4585	Histidine kinase
K0V03_06710	COG0842	Transport permease protein
K0V03_06715	COG1131	(ABC) transporter
K0V03_06720	COG0596	Alpha beta hydrolase
K0V03_06725	COG2208	phosphoserine phosphatase activity
K0V03_06730	COG3867	Arabinogalactan endo-beta-1,4-galactanase
K0V03_06735	COG1874	Beta-galactosidase
K0V03_06740	COG3833	ABC-type maltose transport systems, permease component
K0V03_06745	COG1175	transmembrane transport
K0V03_06750	COG2182	Extracellular solute-binding protein
K0V03_06755	COG1609	Transcriptional regulator
K0V03_06760	COG2186	Transcriptional regulator
K0V03_06765	COG1620	l-lactate permease
K0V03_06770	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K0V03_06780	COG5039	Polysaccharide pyruvyl transferase
K0V03_06785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K0V03_06790	COG0110	maltose O-acetyltransferase activity
K0V03_06795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K0V03_06800	COG2244	polysaccharide biosynthetic process
K0V03_06805	COG1216	Glycosyl transferase, family 2
K0V03_06810	COG5039	Polysaccharide pyruvyl transferase
K0V03_06815	COG1216	Glycosyl transferase, family 2
K0V03_06825	COG0438	transferase activity, transferring glycosyl groups
K0V03_06830	COG1215	transferase activity, transferring glycosyl groups
K0V03_06835	COG0438	transferase activity, transferring glycosyl groups
K0V03_06840	COG1086	Polysaccharide biosynthesis protein
K0V03_06845	COG0489	protein tyrosine kinase activity
K0V03_06850	COG3944	biosynthesis protein
K0V03_06855	COG1396	sequence-specific DNA binding
K0V03_06860	COG2272	Belongs to the type-B carboxylesterase lipase family
K0V03_06870	COG3479	Phenolic acid decarboxylase
K0V03_06880	COG1794	racemase activity, acting on amino acids and derivatives
K0V03_06885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K0V03_06895	COG1621	beta-fructofuranosidase activity
K0V03_06900	COG1621	beta-fructofuranosidase activity
K0V03_06905	COG0531	amino acid
K0V03_06910	COG1309	transcriptional regulator
K0V03_06915	COG2076	Multidrug Resistance protein
K0V03_06920	COG2076	Multidrug Resistance protein
K0V03_07050	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K0V03_07060	COG4974	Belongs to the 'phage' integrase family
K0V03_07070	COG0740	serine-type endopeptidase activity
K0V03_07075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K0V03_07080	COG0366	Alpha amylase catalytic
K0V03_07085	COG1554	hydrolase, family 65, central catalytic
K0V03_07090	COG5521	maltodextrose utilization protein MalA
K0V03_07095	COG3833	ABC-type maltose transport systems, permease component
K0V03_07100	COG1175	transmembrane transport
K0V03_07105	COG2182	Extracellular solute-binding protein
K0V03_07110	COG0366	Alpha amylase catalytic
K0V03_07115	COG1609	Transcriptional regulator
K0V03_07120	COG1611	Belongs to the LOG family
K0V03_07125	COG1694	Mazg nucleotide pyrophosphohydrolase
K0V03_07130	COG0659	secondary active sulfate transmembrane transporter activity
K0V03_07135	COG0288	reversible hydration of carbon dioxide
K0V03_07140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K0V03_07145	COG0577	efflux transmembrane transporter activity
K0V03_07150	COG1136	(ABC) transporter
K0V03_07155	COG5002	protein histidine kinase activity
K0V03_07160	COG0745	RESPONSE REGULATOR receiver
K0V03_07170	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K0V03_07175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K0V03_07180	COG1481	regulation of sporulation
K0V03_07185	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K0V03_07190	COG1660	Displays ATPase and GTPase activities
K0V03_07195	COG1051	belongs to the nudix hydrolase family
K0V03_07200	COG0492	ferredoxin-NADP+ reductase activity
K0V03_07205	COG0791	NLP P60 protein
K0V03_07205	COG3883	PFAM NLP P60 protein
K0V03_07210	COG0457	Tetratricopeptide repeat
K0V03_07215	COG1132	(ABC) transporter
K0V03_07250	COG0140	phosphoribosyl-ATP diphosphatase activity
K0V03_07250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K0V03_07255	COG0107	imidazoleglycerol-phosphate synthase activity
K0V03_07260	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K0V03_07265	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K0V03_07270	COG0131	Imidazoleglycerol-phosphate dehydratase
K0V03_07275	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K0V03_07280	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K0V03_07285	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
K0V03_07290	COG4990	cell redox homeostasis
K0V03_07295	COG5297	Belongs to the glycosyl hydrolase family 6
K0V03_07300	COG0110	maltose O-acetyltransferase activity
K0V03_07305	COG0546	phosphoglycolate phosphatase activity
K0V03_07310	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K0V03_07315	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K0V03_07320	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
K0V03_07325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K0V03_07330	COG0363	glucosamine-6-phosphate deaminase activity
K0V03_07335	COG2188	Transcriptional regulator
K0V03_07340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K0V03_07345	COG1846	Transcriptional regulator
K0V03_07350	COG2124	cytochrome p450
K0V03_07360	COG1846	Transcriptional regulator
K0V03_07365	COG2814	Major facilitator Superfamily
K0V03_07370	COG1950	PFAM Membrane protein of
K0V03_07375	COG1983	PspC domain protein
K0V03_07380	COG3595	metallopeptidase activity
K0V03_07395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K0V03_07400	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K0V03_07405	COG0556	nucleotide-excision repair
K0V03_07410	COG4897	Protein conserved in bacteria
K0V03_07415	COG3848	Pyruvate phosphate dikinase
K0V03_07415	COG0574	Belongs to the PEP-utilizing enzyme family
K0V03_07420	COG1309	transcriptional regulator
K0V03_07425	COG2814	Major facilitator Superfamily
K0V03_07430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K0V03_07440	COG0793	Belongs to the peptidase S41A family
K0V03_07440	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_07445	COG2177	Part of the ABC transporter FtsEX involved in
K0V03_07450	COG2884	Cell division ATP-binding protein ftsE
K0V03_07455	COG2010	Cytochrome c
K0V03_07460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K0V03_07470	COG0653	protein targeting
K0V03_07475	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K0V03_07490	COG1516	flagellar protein fliS
K0V03_07495	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K0V03_07500	COG1334	flagellar protein FlaG
K0V03_07505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K0V03_07510	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
K0V03_07515	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
K0V03_07525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K0V03_07530	COG1256	bacterial-type flagellum assembly
K0V03_07530	COG4786	Flagellar basal body rod
K0V03_07535	COG3418	PFAM FlgN family protein
K0V03_07540	COG2747	anti-sigma28 factor FlgM
K0V03_07550	COG1040	competence protein
K0V03_07560	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K0V03_07565	COG1307	EDD domain protein, DegV family
K0V03_07570	COG2197	response regulator
K0V03_07575	COG4585	Histidine kinase
K0V03_07580	COG1739	Uncharacterized protein family UPF0029
K0V03_07585	COG1316	TRANSCRIPTIONal
K0V03_07615	COG1131	(ABC) transporter
K0V03_07625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K0V03_07630	COG0438	transferase activity, transferring glycosyl groups
K0V03_07635	COG1215	transferase activity, transferring glycosyl groups
K0V03_07640	COG3206	protein involved in exopolysaccharide biosynthesis
K0V03_07645	COG3307	-O-antigen
K0V03_07650	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K0V03_07655	COG0297	glycogen (starch) synthase activity
K0V03_07655	COG0438	transferase activity, transferring glycosyl groups
K0V03_07660	COG2244	polysaccharide biosynthetic process
K0V03_07670	COG0860	N-Acetylmuramoyl-L-alanine amidase
K0V03_07670	COG2247	cell wall binding repeat
K0V03_07675	COG2247	cell wall binding repeat
K0V03_07675	COG2385	sporulation resulting in formation of a cellular spore
K0V03_07690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K0V03_07695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K0V03_07705	COG1134	teichoic acid transport
K0V03_07710	COG1682	transport, permease protein
K0V03_07725	COG0463	Glycosyl transferase, family 2
K0V03_07725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K0V03_07730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K0V03_07735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K0V03_07740	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
K0V03_07745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K0V03_07750	COG4193	domain, Protein
K0V03_07755	COG1482	cell wall glycoprotein biosynthetic process
K0V03_07760	COG0697	spore germination
K0V03_07765	COG0814	amino acid
K0V03_07775	COG2814	Major facilitator Superfamily
K0V03_07780	COG1316	TRANSCRIPTIONal
K0V03_07785	COG0561	phosphatase activity
K0V03_07790	COG0791	NLP P60 protein
K0V03_07800	COG2843	Capsule synthesis protein
K0V03_07810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K0V03_07815	COG1609	Transcriptional regulator
K0V03_07820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K0V03_07825	COG1869	D-ribose catabolic process
K0V03_07830	COG1129	ABC transporter
K0V03_07835	COG1172	Belongs to the binding-protein-dependent transport system permease family
K0V03_07840	COG1879	ABC-type sugar transport system periplasmic component
K0V03_07845	COG3103	Sh3 type 3 domain protein
K0V03_07855	COG2249	NAD(P)H dehydrogenase (quinone) activity
K0V03_07860	COG3527	Alpha-acetolactate decarboxylase
K0V03_07865	COG0028	Belongs to the TPP enzyme family
K0V03_07870	COG0583	DNA-binding transcription factor activity
K0V03_07875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K0V03_07890	COG5337	Spore coat protein CotH
K0V03_07900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K0V03_07910	COG0405	Gamma-glutamyltransferase
K0V03_07915	COG1522	sequence-specific DNA binding
K0V03_07920	COG2059	Chromate
K0V03_07925	COG2059	Chromate
K0V03_07935	COG0655	NAD(P)H dehydrogenase (quinone) activity
K0V03_07940	COG0583	DNA-binding transcription factor activity
K0V03_07970	COG5444	nuclease activity
K0V03_07990	COG3878	Protein conserved in bacteria
K0V03_07995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K0V03_08000	COG4464	protein tyrosine phosphatase activity
K0V03_08005	COG0489	protein tyrosine kinase activity
K0V03_08010	COG3944	biosynthesis protein
K0V03_08020	COG4715	Zinc finger, swim domain protein
K0V03_08025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K0V03_08030	COG0561	phosphatase activity
K0V03_08035	COG1349	DNA-binding transcription factor activity
K0V03_08040	COG0629	single-stranded DNA binding
K0V03_08055	COG3764	Sortase (surface protein transpeptidase)
K0V03_08065	COG3279	Response regulator of the LytR AlgR family
K0V03_08070	COG0745	RESPONSE REGULATOR receiver
K0V03_08070	COG2972	Histidine kinase
K0V03_08075	COG1970	mechanosensitive ion channel activity
K0V03_08080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K0V03_08085	COG0457	Tetratricopeptide repeat
K0V03_08090	COG4786	Flagellar basal body rod
K0V03_08095	COG4786	Flagellar basal body rod
K0V03_08100	COG1077	Cell shape determining protein MreB Mrl
K0V03_08105	COG1609	Transcriptional regulator
K0V03_08115	COG1846	Transcriptional regulator
K0V03_08120	COG2814	Major facilitator Superfamily
K0V03_08125	COG3420	alginic acid biosynthetic process
K0V03_08130	COG1953	Uracil, thiamine, allantoin
K0V03_08135	COG0477	Major facilitator Superfamily
K0V03_08140	COG1335	isochorismatase
K0V03_08150	COG0004	ammonium transporteR
K0V03_08155	COG0347	Belongs to the P(II) protein family
K0V03_08160	COG0671	phosphoesterase, PA-phosphatase related
K0V03_08170	COG0739	heme binding
K0V03_08175	COG1247	-acetyltransferase
K0V03_08185	COG2089	acid synthase
K0V03_08195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K0V03_08200	COG0789	Transcriptional regulator
K0V03_08210	COG2910	NAD(P)H-binding
K0V03_08215	COG1959	2 iron, 2 sulfur cluster binding
K0V03_08220	COG0804	urea catabolic process
K0V03_08225	COG0832	Belongs to the urease beta subunit family
K0V03_08230	COG0831	urea catabolic process
K0V03_08245	COG3237	CsbD-like
K0V03_08250	COG1994	Peptidase M50
K0V03_08255	COG0457	Tetratricopeptide repeat
K0V03_08260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K0V03_08265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K0V03_08275	COG2304	oxidoreductase activity
K0V03_08285	COG2304	oxidoreductase activity
K0V03_08290	COG2385	sporulation resulting in formation of a cellular spore
K0V03_08295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K0V03_08305	COG4836	Membrane
K0V03_08315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K0V03_08320	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K0V03_08325	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K0V03_08330	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K0V03_08335	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K0V03_08340	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K0V03_08350	COG0356	it plays a direct role in the translocation of protons across the membrane
K0V03_08360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K0V03_08365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K0V03_08370	COG4475	Protein of unknown function (DUF436)
K0V03_08375	COG0698	ribose 5-phosphate isomerase
K0V03_08380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K0V03_08385	COG1971	Probably functions as a manganese efflux pump
K0V03_08390	COG0009	L-threonylcarbamoyladenylate synthase
K0V03_08395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K0V03_08415	COG2890	protein-(glutamine-N5) methyltransferase activity
K0V03_08420	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K0V03_08425	COG0346	lactoylglutathione lyase activity
K0V03_08430	COG0789	Transcriptional regulator
K0V03_08435	COG0679	Auxin Efflux Carrier
K0V03_08440	COG0281	malic enzyme
K0V03_08445	COG1435	thymidine kinase activity
K0V03_08455	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K0V03_08465	COG1494	fructose-1,6-bisphosphatase
K0V03_08470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K0V03_08475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K0V03_08480	COG0191	fructose-bisphosphate aldolase activity
K0V03_08485	COG2204	response regulator
K0V03_08490	COG4821	SIS domain
K0V03_08495	COG0504	CTP synthase activity
K0V03_08500	COG3343	RNA polymerase activity
K0V03_08505	COG1960	acyl-CoA dehydrogenase activity
K0V03_08510	COG0247	lactate metabolic process
K0V03_08510	COG2181	nitrate reductase activity
K0V03_08515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K0V03_08520	COG4294	response to UV
K0V03_08530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K0V03_08535	COG1132	(ABC) transporter
K0V03_08540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K0V03_08545	COG2181	nitrate reductase activity
K0V03_08550	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K0V03_08555	COG1140	nitrate reductase beta subunit
K0V03_08560	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
K0V03_08565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K0V03_08575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K0V03_08580	COG2223	nitrite transmembrane transporter activity
K0V03_08585	COG0018	arginyl-trna synthetase
K0V03_08590	COG4506	Protein conserved in bacteria
K0V03_08605	COG0535	radical SAM domain protein
K0V03_08615	COG1131	(ABC) transporter
K0V03_08620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K0V03_08625	COG0612	Peptidase, M16
K0V03_08630	COG0612	Peptidase, M16
K0V03_08640	COG3391	amine dehydrogenase activity
K0V03_08645	COG0457	Tetratricopeptide repeat
K0V03_08660	COG0010	Belongs to the arginase family
K0V03_08665	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K0V03_08670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K0V03_08685	COG1994	Peptidase M50
K0V03_08690	COG1942	4-Oxalocrotonate Tautomerase
K0V03_08695	COG1846	Transcriptional regulator
K0V03_08700	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K0V03_08705	COG0477	Major facilitator Superfamily
K0V03_08710	COG1959	2 iron, 2 sulfur cluster binding
K0V03_08715	COG3465	dGTPase activity
K0V03_08720	COG1078	dGTPase activity
K0V03_08725	COG4844	belongs to the
K0V03_08735	COG0697	spore germination
K0V03_08740	COG0095	Lipoate-protein ligase
K0V03_08745	COG0583	DNA-binding transcription factor activity
K0V03_08750	COG0280	phosphate acetyltransferase
K0V03_08755	COG3253	May function as heme-dependent peroxidase
K0V03_08760	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_08765	COG0436	Aminotransferase
K0V03_08770	COG2814	Major facilitator Superfamily
K0V03_08775	COG0151	Belongs to the GarS family
K0V03_08780	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_08785	COG1917	Cupin 2, conserved barrel domain protein
K0V03_08790	COG0077	Prephenate dehydratase
K0V03_08795	COG2814	Major facilitator Superfamily
K0V03_08800	COG0833	amino acid
K0V03_08805	COG4187	Peptidase family M20/M25/M40
K0V03_08810	COG1012	belongs to the aldehyde dehydrogenase family
K0V03_08815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K0V03_08825	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
K0V03_08830	COG1091	dTDP-4-dehydrorhamnose reductase activity
K0V03_08835	COG1088	dTDP-glucose 4,6-dehydratase activity
K0V03_08840	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K0V03_08845	COG3980	spore coat polysaccharide biosynthesis protein
K0V03_08850	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
K0V03_08855	COG2089	acid synthase
K0V03_08860	COG0456	acetyltransferase
K0V03_08865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K0V03_08870	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K0V03_08875	COG0463	Glycosyl transferase, family 2
K0V03_08885	COG2363	Small membrane protein
K0V03_08890	COG2233	PERMEase
K0V03_08900	COG1012	belongs to the aldehyde dehydrogenase family
K0V03_08905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K0V03_08910	COG1216	Glycosyl transferase, family 2
K0V03_08915	COG0351	phosphomethylpyrimidine kinase
K0V03_08925	COG1621	beta-fructofuranosidase activity
K0V03_08930	COG1263	PTS System
K0V03_08930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K0V03_08935	COG2116	formate transmembrane transporter activity
K0V03_08940	COG3711	transcriptional antiterminator
K0V03_08950	COG1404	Belongs to the peptidase S8 family
K0V03_08955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K0V03_08960	COG0778	Nitroreductase
K0V03_08965	COG0772	Belongs to the SEDS family
K0V03_08975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K0V03_08980	COG1845	cytochrome c oxidase, subunit III
K0V03_08985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K0V03_08990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K0V03_08995	COG2261	transglycosylase associated protein
K0V03_09000	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
K0V03_09005	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
K0V03_09010	COG2246	polysaccharide biosynthetic process
K0V03_09015	COG1309	transcriptional regulator
K0V03_09025	COG3162	membrane
K0V03_09030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K0V03_09035	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K0V03_09040	COG2837	iron assimilation
K0V03_09045	COG2822	iron ion transport
K0V03_09050	COG0672	)-iron permease
K0V03_09055	COG0352	thiamine-phosphate diphosphorylase activity
K0V03_09060	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
K0V03_09065	COG0583	DNA-binding transcription factor activity
K0V03_09070	COG1380	Effector of murein hydrolase LrgA
K0V03_09075	COG1346	cytolysis
K0V03_09080	COG2814	Major facilitator Superfamily
K0V03_09085	COG4895	conserved protein (DUF2196)
K0V03_09090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K0V03_09095	COG0346	lactoylglutathione lyase activity
K0V03_09105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K0V03_09110	COG1404	Belongs to the peptidase S8 family
K0V03_09115	COG1263	PTS System
K0V03_09115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K0V03_09120	COG3711	transcriptional antiterminator
K0V03_09125	COG1442	glycosyl transferase family 8
K0V03_09130	COG5522	Integral membrane protein (intg_mem_TP0381)
K0V03_09135	COG1846	Transcriptional regulator
K0V03_09140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K0V03_09145	COG2234	aminopeptidase activity
K0V03_09150	COG2357	RelA SpoT domain protein
K0V03_09155	COG1575	Belongs to the MenA family. Type 1 subfamily
K0V03_09170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K0V03_09175	COG1696	Membrane protein involved in D-alanine export
K0V03_09180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K0V03_09185	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K0V03_09190	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
K0V03_09195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K0V03_09200	COG1486	melibiose metabolic process
K0V03_09205	COG1447	Phosphotransferase system cellobiose-specific component IIA
K0V03_09210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K0V03_09215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K0V03_09220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K0V03_09220	COG3711	transcriptional antiterminator
K0V03_09230	COG2094	Belongs to the DNA glycosylase MPG family
K0V03_09235	COG0753	catalase activity
K0V03_09240	COG2814	Major facilitator Superfamily
K0V03_09245	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K0V03_09250	COG1131	(ABC) transporter
K0V03_09270	COG1595	DNA-templated transcription, initiation
K0V03_09275	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K0V03_09280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K0V03_09285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K0V03_09290	COG4988	ABC transporter
K0V03_09295	COG1294	oxidase, subunit
K0V03_09300	COG1271	oxidase subunit
K0V03_09305	COG3493	citrate carrier protein
K0V03_09310	COG0501	Belongs to the peptidase M48B family
K0V03_09320	COG0726	polysaccharide deacetylase
K0V03_09325	COG3842	ATPase activity
K0V03_09330	COG2508	Transcriptional regulator
K0V03_09340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K0V03_09345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K0V03_09355	COG4585	Histidine kinase
K0V03_09360	COG2197	response regulator
K0V03_09365	COG2195	Cleaves the N-terminal amino acid of tripeptides
K0V03_09375	COG4894	glucomannan catabolic process
K0V03_09380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
K0V03_09385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
K0V03_09390	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_09395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K0V03_09400	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K0V03_09405	COG2610	gluconate transmembrane transporter activity
K0V03_09410	COG0500	methyltransferase
K0V03_09415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K0V03_09430	COG0693	protein deglycase activity
K0V03_09430	COG0753	catalase activity
K0V03_09435	COG2851	Citrate transporter
K0V03_09440	COG2273	Hydrolase Family 16
K0V03_09445	COG3711	transcriptional antiterminator
K0V03_09455	COG2270	Major facilitator Superfamily
K0V03_09460	COG0513	Belongs to the DEAD box helicase family
K0V03_09465	COG3401	FG-GAP repeat protein
K0V03_09465	COG2755	lipolytic protein G-D-S-L family
K0V03_09585	COG0697	spore germination
K0V03_09590	COG0589	response to stress
K0V03_09595	COG2723	6-phospho-beta-galactosidase activity
K0V03_09600	COG2190	(PTS) system
K0V03_09600	COG1263	PTS System
K0V03_09600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K0V03_09630	COG0494	nUDIX hydrolase
K0V03_09640	COG3507	Belongs to the glycosyl hydrolase 43 family
K0V03_09655	COG2986	histidine ammonia-lyase
K0V03_09660	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K0V03_09665	COG1228	amidohydrolase
K0V03_09670	COG0010	Belongs to the arginase family
K0V03_09675	COG0833	amino acid
K0V03_09680	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K0V03_09685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K0V03_09690	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K0V03_09695	COG2390	Transcriptional regulator
K0V03_09705	COG3192	ethanolamine utilization protein
K0V03_09710	COG2079	MmgE PrpD family protein
K0V03_09715	COG1473	amidohydrolase
K0V03_09720	COG1126	abc transporter atp-binding protein
K0V03_09725	COG0765	amino acid transport
K0V03_09730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K0V03_09735	COG0456	acetyltransferase
K0V03_09740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K0V03_09745	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K0V03_09750	COG0561	phosphatase activity
K0V03_09780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K0V03_09785	COG5294	Protein conserved in bacteria
K0V03_09790	COG0577	efflux transmembrane transporter activity
K0V03_09795	COG1136	(ABC) transporter
K0V03_09800	COG2205	protein histidine kinase activity
K0V03_09805	COG0745	RESPONSE REGULATOR receiver
K0V03_09810	COG0191	fructose-bisphosphate aldolase activity
K0V03_09815	COG1082	Xylose isomerase domain protein TIM barrel
K0V03_09820	COG1082	Xylose isomerase domain protein TIM barrel
K0V03_09825	COG0673	inositol 2-dehydrogenase activity
K0V03_09830	COG2814	Major facilitator Superfamily
K0V03_09835	COG1082	Xylose isomerase domain protein TIM barrel
K0V03_09840	COG3962	Belongs to the TPP enzyme family
K0V03_09845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K0V03_09855	COG1012	belongs to the aldehyde dehydrogenase family
K0V03_09860	COG1349	DNA-binding transcription factor activity
K0V03_09865	COG0667	Aldo Keto reductase
K0V03_09880	COG2814	Major facilitator Superfamily
K0V03_09885	COG0326	Molecular chaperone. Has ATPase activity
K0V03_09895	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_09900	COG1309	transcriptional regulator
K0V03_09905	COG1012	belongs to the aldehyde dehydrogenase family
K0V03_09910	COG1714	RDD family
K0V03_09920	COG1714	RDD family
K0V03_09925	COG2311	Membrane
K0V03_09930	COG1917	Cupin 2, conserved barrel domain protein
K0V03_09935	COG1309	transcriptional regulator
K0V03_09940	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_09945	COG1846	Transcriptional regulator
K0V03_09950	COG1380	Effector of murein hydrolase LrgA
K0V03_09955	COG1346	cytolysis
K0V03_09960	COG5039	Polysaccharide pyruvyl transferase
K0V03_09965	COG1929	Belongs to the glycerate kinase type-1 family
K0V03_09970	COG1802	Transcriptional regulator
K0V03_09975	COG1070	Carbohydrate kinase
K0V03_09980	COG2610	gluconate transmembrane transporter activity
K0V03_09985	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K0V03_09990	COG0450	alkyl hydroperoxide reductase
K0V03_09995	COG3634	alkyl hydroperoxide reductase activity
K0V03_10020	COG1131	(ABC) transporter
K0V03_10025	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
K0V03_10045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K0V03_10080	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
K0V03_10085	COG0456	acetyltransferase
K0V03_10090	COG0457	Tetratricopeptide repeat
K0V03_10100	COG0010	Belongs to the arginase family
K0V03_10105	COG0833	amino acid
K0V03_10110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K0V03_10115	COG5658	integral membrane protein
K0V03_10120	COG0640	Transcriptional regulator
K0V03_10125	COG3829	transcription factor binding
K0V03_10140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K0V03_10145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K0V03_10150	COG4853	Protein conserved in bacteria
K0V03_10155	COG4863	YycH protein
K0V03_10160	COG5002	protein histidine kinase activity
K0V03_10165	COG0745	RESPONSE REGULATOR receiver
K0V03_10195	COG0346	lactoylglutathione lyase activity
K0V03_10200	COG0305	Participates in initiation and elongation during chromosome replication
K0V03_10215	COG3093	addiction module antidote protein HigA
K0V03_10220	COG2807	transmembrane transport
K0V03_10225	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K0V03_10230	COG0359	binds to the 23S rRNA
K0V03_10235	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K0V03_10240	COG4241	membrane
K0V03_10250	COG5577	PFAM Coat F domain
K0V03_10255	COG1733	regulation of RNA biosynthetic process
K0V03_10260	COG1227	inorganic diphosphatase activity
K0V03_10275	COG2271	Major facilitator Superfamily
K0V03_10280	COG0789	Transcriptional regulator
K0V03_10280	COG4978	Transcriptional regulator
K0V03_10290	COG4319	ketosteroid isomerase
K0V03_10295	COG1357	PFAM Pentapeptide repeats (8 copies)
K0V03_10300	COG2814	Major facilitator Superfamily
K0V03_10305	COG0583	DNA-binding transcription factor activity
K0V03_10310	COG2153	protein acetylation
K0V03_10320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K0V03_10325	COG1846	Transcriptional regulator
K0V03_10330	COG2153	protein acetylation
K0V03_10335	COG2364	Membrane
K0V03_10340	COG0456	acetyltransferase
K0V03_10345	COG2315	Protein conserved in bacteria
K0V03_10350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K0V03_10355	COG1331	Highly conserved protein containing a thioredoxin domain
K0V03_10360	COG2814	Major facilitator Superfamily
K0V03_10370	COG1331	Highly conserved protein containing a thioredoxin domain
K0V03_10375	COG0789	Transcriptional regulator
K0V03_10380	COG0697	spore germination
K0V03_10385	COG1331	Highly conserved protein containing a thioredoxin domain
K0V03_10390	COG1266	CAAX protease self-immunity
K0V03_10395	COG2814	Major facilitator Superfamily
K0V03_10395	COG0477	Major facilitator Superfamily
K0V03_10400	COG0110	maltose O-acetyltransferase activity
K0V03_10405	COG0346	lactoylglutathione lyase activity
K0V03_10410	COG1609	Transcriptional regulator
K0V03_10415	COG0708	Exodeoxyribonuclease III
K0V03_10420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K0V03_10425	COG0629	single-stranded DNA binding
K0V03_10430	COG0360	Binds together with S18 to 16S ribosomal RNA
K0V03_10435	COG0012	GTP binding
K0V03_10440	COG0243	molybdopterin cofactor binding
K0V03_10445	COG4481	Protein conserved in bacteria
K0V03_10450	COG3949	Membrane
K0V03_10460	COG1475	DNA binding
K0V03_10465	COG1192	Involved in chromosome partitioning
K0V03_10475	COG1475	DNA binding
K0V03_10480	COG0357	Ribosomal RNA small subunit methyltransferase G
K0V03_10490	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K0V03_10495	COG1847	R3H domain protein
K0V03_10500	COG0706	membrane insertase activity
K0V03_10505	COG0594	ribonuclease P activity
K0V03_10515	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K0V03_10520	COG0592	DNA-directed DNA polymerase activity
K0V03_10525	COG2501	S4 domain
K0V03_10530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K0V03_10540	COG0187	DNA topoisomerase II activity
K0V03_10545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K0V03_10580	COG0516	GMP reductase activity
K0V03_10580	COG0517	IMP dehydrogenase activity
K0V03_10585	COG1686	Belongs to the peptidase S11 family
K0V03_10590	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
K0V03_10595	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
K0V03_10600	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K0V03_10610	COG1428	Deoxynucleoside kinase
K0V03_10615	COG1428	Deoxynucleoside kinase
K0V03_10620	COG1388	LysM domain
K0V03_10620	COG3858	chitin binding
K0V03_10625	COG1335	isochorismatase
K0V03_10630	COG0590	tRNA wobble adenosine to inosine editing
K0V03_10640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K0V03_10645	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K0V03_10650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K0V03_10695	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
K0V03_10700	COG3853	Toxic anion resistance protein (TelA)
K0V03_10705	COG1982	Orn Lys Arg decarboxylase major
K0V03_10710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K0V03_10715	COG3870	Protein conserved in bacteria
K0V03_10720	COG1728	Protein conserved in bacteria
K0V03_10725	COG0470	DNA polymerase III
K0V03_10730	COG1774	PSP1 C-terminal conserved region
K0V03_10735	COG4467	Involved in initiation control of chromosome replication
K0V03_10740	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K0V03_10745	COG2827	Endonuclease containing a URI domain
K0V03_10750	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K0V03_10755	COG2002	toxin-antitoxin pair type II binding
K0V03_10760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K0V03_10760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K0V03_10765	COG0084	hydrolase, TatD family'
K0V03_10770	COG3583	domain protein
K0V03_10770	COG3584	3D domain protein
K0V03_10775	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K0V03_10780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K0V03_10790	COG4466	Protein conserved in bacteria
K0V03_10800	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K0V03_10805	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K0V03_10810	COG0251	oxidation-reduction process
K0V03_10815	COG2088	sporulation resulting in formation of a cellular spore
K0V03_10820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K0V03_10825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K0V03_10830	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K0V03_10835	COG0193	aminoacyl-tRNA hydrolase activity
K0V03_10845	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K0V03_10850	COG2002	toxin-antitoxin pair type II binding
K0V03_10855	COG2244	polysaccharide biosynthetic process
K0V03_10860	COG3956	TIGRFAM MazG family protein
K0V03_10865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K0V03_10880	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
K0V03_10885	COG1098	S1 RNA binding domain
K0V03_10900	COG2208	phosphoserine phosphatase activity
K0V03_10905	COG2304	oxidoreductase activity
K0V03_10910	COG0515	serine threonine protein kinase
K0V03_10915	COG0037	tRNA processing
K0V03_10920	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K0V03_10925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K0V03_10930	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
K0V03_10935	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
K0V03_10940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K0V03_10945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K0V03_10950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K0V03_10955	COG0512	Glutamine amidotransferase of anthranilate synthase
K0V03_10960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K0V03_10965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K0V03_10970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K0V03_10975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K0V03_10980	COG1396	sequence-specific DNA binding
K0V03_10985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K0V03_10990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K0V03_11070	COG4463	regulation of RNA biosynthetic process
K0V03_11075	COG3880	PFAM UvrB UvrC protein
K0V03_11080	COG3869	Catalyzes the specific phosphorylation of arginine residues in
K0V03_11085	COG0542	response to heat
K0V03_11090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K0V03_11095	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
K0V03_11100	COG4956	integral membrane protein (PIN domain superfamily)
K0V03_11105	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K0V03_11110	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K0V03_11115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K0V03_11120	COG1045	serine acetyltransferase
K0V03_11125	COG0215	cysteine-tRNA ligase activity
K0V03_11130	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
K0V03_11135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K0V03_11140	COG3688	RNA-binding protein containing a PIN domain
K0V03_11145	COG1595	DNA-templated transcription, initiation
K0V03_11155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K0V03_11160	COG0250	Participates in transcription elongation, termination and antitermination
K0V03_11170	COG0081	regulation of translation
K0V03_11175	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K0V03_11185	COG2813	Specifically methylates the guanine in position
K0V03_11190	COG0085	RNA polymerase activity
K0V03_11195	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K0V03_11200	COG1358	cellular component organization or biogenesis
K0V03_11205	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K0V03_11210	COG0049	tRNA binding
K0V03_11215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K0V03_11220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K0V03_11225	COG0596	Alpha beta hydrolase
K0V03_11235	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K0V03_11240	COG0088	Forms part of the polypeptide exit tunnel
K0V03_11250	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K0V03_11270	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K0V03_11280	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K0V03_11285	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K0V03_11295	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K0V03_11305	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K0V03_11310	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K0V03_11315	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K0V03_11320	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K0V03_11330	COG0200	Binds to the 23S rRNA
K0V03_11335	COG0201	protein transport
K0V03_11340	COG0563	adenylate kinase activity
K0V03_11345	COG0024	Methionine aminopeptidase
K0V03_11360	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K0V03_11365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K0V03_11370	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K0V03_11375	COG0202	RNA polymerase activity
K0V03_11380	COG0203	ribosomal protein L17
K0V03_11385	COG1122	ATPase activity
K0V03_11390	COG1122	ATPase activity
K0V03_11395	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K0V03_11400	COG0101	tRNA pseudouridine synthase activity
K0V03_11405	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K0V03_11410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K0V03_11415	COG0582	viral genome integration into host DNA
K0V03_11595	COG5412	phage tail tape measure protein
K0V03_11595	COG3953	SLT domain
K0V03_11630	COG4824	toxin secretion phage lysis holin
K0V03_11635	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_11635	COG5632	N-Acetylmuramoyl-L-alanine amidase
K0V03_11645	COG5444	nuclease activity
K0V03_11650	COG0457	Tetratricopeptide repeat
K0V03_11670	COG2226	methyltransferase
K0V03_11680	COG0860	N-Acetylmuramoyl-L-alanine amidase
K0V03_11685	COG0489	protein tyrosine kinase activity
K0V03_11695	COG2194	sulfuric ester hydrolase activity
K0V03_11700	COG0726	polysaccharide deacetylase
K0V03_11780	COG0659	secondary active sulfate transmembrane transporter activity
K0V03_11785	COG0385	Bile acid
K0V03_11790	COG2819	hydrolase of the alpha beta superfamily
K0V03_11795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K0V03_11800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K0V03_11805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K0V03_11810	COG2207	Transcriptional regulator
K0V03_11810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K0V03_11815	COG3876	Protein conserved in bacteria
K0V03_11820	COG1472	Belongs to the glycosyl hydrolase 3 family
K0V03_11825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K0V03_11830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K0V03_11830	COG1263	PTS System
K0V03_11835	COG1737	Transcriptional regulator
K0V03_11840	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K0V03_11845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K0V03_11850	COG1683	Conserved Protein
K0V03_11880	COG1595	DNA-templated transcription, initiation
K0V03_11885	COG5662	AntiSigma factor
K0V03_11890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K0V03_11895	COG4856	YbbR-like protein
K0V03_11900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K0V03_11905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K0V03_11925	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K0V03_11930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K0V03_11935	COG3002	Belongs to the UPF0753 family
K0V03_11940	COG0288	reversible hydration of carbon dioxide
K0V03_11950	COG5609	conserved protein (DUF2294)
K0V03_11955	COG0640	Transcriptional regulator
K0V03_11960	COG2814	Major facilitator Superfamily
K0V03_11975	COG0515	serine threonine protein kinase
K0V03_11990	COG1113	amino acid transport
K0V03_12005	COG2602	Beta-lactamase
K0V03_12010	COG2124	cytochrome p450
K0V03_12020	COG0531	amino acid
K0V03_12025	COG0584	glycerophosphoryl diester phosphodiesterase
K0V03_12030	COG2271	Major facilitator Superfamily
K0V03_12040	COG0456	acetyltransferase
K0V03_12040	COG1846	Transcriptional regulator
K0V03_12045	COG2271	Major facilitator Superfamily
K0V03_12055	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_12060	COG0697	spore germination
K0V03_12065	COG1917	Cupin 2, conserved barrel domain protein
K0V03_12065	COG2207	Transcriptional regulator
K0V03_12090	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
K0V03_12095	COG3591	Belongs to the peptidase S1B family
K0V03_12105	COG0596	Alpha beta hydrolase
K0V03_12110	COG1183	phosphatidylcholine synthase activity
K0V03_12115	COG0586	Pfam SNARE associated Golgi protein
K0V03_12120	COG0688	phosphatidylethanolamine metabolic process
K0V03_12130	COG2312	Erythromycin esterase
K0V03_12135	COG1054	Belongs to the UPF0176 family
K0V03_12140	COG1301	dicarboxylic acid transport
K0V03_12145	COG2190	(PTS) system
K0V03_12145	COG1263	PTS System
K0V03_12145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K0V03_12150	COG0363	glucosamine-6-phosphate deaminase activity
K0V03_12155	COG2188	Transcriptional regulator
K0V03_12165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K0V03_12170	COG0833	amino acid
K0V03_12175	COG2040	homocysteine
K0V03_12180	COG1115	amino acid carrier protein
K0V03_12185	COG2066	Belongs to the glutaminase family
K0V03_12190	COG4191	Histidine kinase
K0V03_12195	COG0784	Response regulator, receiver
K0V03_12200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K0V03_12205	COG1012	belongs to the aldehyde dehydrogenase family
K0V03_12210	COG2271	Major facilitator Superfamily
K0V03_12215	COG4948	Mandelate Racemase Muconate Lactonizing
K0V03_12220	COG2186	Transcriptional regulator
K0V03_12225	COG2721	sulfolactate sulfo-lyase activity
K0V03_12230	COG3173	Aminoglycoside phosphotransferase
K0V03_12240	COG0697	spore germination
K0V03_12245	COG0745	RESPONSE REGULATOR receiver
K0V03_12250	COG2205	protein histidine kinase activity
K0V03_12255	COG1131	(ABC) transporter
K0V03_12275	COG3773	Cell wall hydrolase
K0V03_12280	COG2304	oxidoreductase activity
K0V03_12290	COG3540	Alkaline phosphatase
K0V03_12295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K0V03_12300	COG0805	protein transport
K0V03_12305	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
K0V03_12310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K0V03_12315	COG0477	Major facilitator Superfamily
K0V03_12320	COG1309	transcriptional regulator
K0V03_12325	COG0252	asparaginase activity
K0V03_12330	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
K0V03_12335	COG1714	RDD family
K0V03_12340	COG1405	negative regulation of cell septum assembly
K0V03_12340	COG3012	SEC-C Motif Domain Protein
K0V03_12345	COG3290	protein histidine kinase activity
K0V03_12350	COG3279	Response regulator of the LytR AlgR family
K0V03_12355	COG4555	ABC transporter
K0V03_12360	COG1668	transmembrane transport
K0V03_12365	COG0667	Aldo Keto reductase
K0V03_12380	COG1595	DNA-templated transcription, initiation
K0V03_12385	COG1595	DNA-templated transcription, initiation
K0V03_12390	COG1876	peptidase activity
K0V03_12395	COG0457	Tetratricopeptide repeat
K0V03_12400	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_12405	COG0366	Alpha amylase catalytic
K0V03_12410	COG0803	Belongs to the bacterial solute-binding protein 9 family
K0V03_12415	COG1121	(ABC) transporter
K0V03_12420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K0V03_12425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K0V03_12430	COG2310	stress, protein
K0V03_12435	COG2310	stress, protein
K0V03_12440	COG2310	stress, protein
K0V03_12445	COG0861	Integral membrane protein TerC family
K0V03_12455	COG3853	Toxic anion resistance protein (TelA)
K0V03_12460	COG0477	Major facilitator Superfamily
K0V03_12470	COG0640	Transcriptional regulator
K0V03_12475	COG0517	IMP dehydrogenase activity
K0V03_12475	COG4175	Glycine betaine
K0V03_12480	COG4176	ABC-type proline glycine betaine transport system permease component
K0V03_12485	COG2113	Glycine betaine
K0V03_12490	COG1473	amidohydrolase
K0V03_12495	COG1288	antiporter activity
K0V03_12505	COG0366	Alpha amylase catalytic
K0V03_12510	COG0039	L-malate dehydrogenase activity
K0V03_12515	COG1620	l-lactate permease
K0V03_12520	COG2814	Major facilitator Superfamily
K0V03_12525	COG1846	Transcriptional regulator
K0V03_12530	COG1280	lysine exporter protein (LysE YggA)
K0V03_12535	COG3403	YqcI/YcgG family
K0V03_12540	COG1113	amino acid transport
K0V03_12545	COG3665	Urea carboxylase-associated protein
K0V03_12550	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K0V03_12555	COG1660	Displays ATPase and GTPase activities
K0V03_12560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K0V03_12565	COG2226	methyltransferase
K0V03_12570	COG0583	DNA-binding transcription factor activity
K0V03_12575	COG3458	cephalosporin-C deacetylase activity
K0V03_12580	COG3541	Predicted nucleotidyltransferase
K0V03_12585	COG0506	proline dehydrogenase activity
K0V03_12590	COG1012	belongs to the aldehyde dehydrogenase family
K0V03_12595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K0V03_12600	COG2508	Transcriptional regulator
K0V03_12605	COG3689	TIGRFAM TIGR03943 family protein
K0V03_12610	COG0701	Predicted permease
K0V03_12620	COG0492	ferredoxin-NADP+ reductase activity
K0V03_12625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K0V03_12625	COG1587	Uroporphyrinogen-III synthase
K0V03_12630	COG2146	nitrite reductase [NAD(P)H] activity
K0V03_12635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K0V03_12640	COG0243	molybdopterin cofactor binding
K0V03_12645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K0V03_12650	COG2223	nitrite transmembrane transporter activity
K0V03_12655	COG1469	GTP cyclohydrolase I activity
K0V03_12660	COG1376	ErfK ybiS ycfS ynhG family protein
K0V03_12670	COG0523	cobalamin synthesis protein
K0V03_12675	COG0765	amino acid transport
K0V03_12680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K0V03_12700	COG1846	Transcriptional regulator
K0V03_12710	COG3842	ATPase activity
K0V03_12715	COG2723	6-phospho-beta-galactosidase activity
K0V03_12725	COG3209	COG3209 Rhs family protein
K0V03_12730	COG0840	transmembrane signaling receptor activity
K0V03_12730	COG3290	protein histidine kinase activity
K0V03_12735	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K0V03_12740	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
K0V03_12745	COG1733	regulation of RNA biosynthetic process
K0V03_12750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K0V03_12755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K0V03_12760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K0V03_12765	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
K0V03_12770	COG2814	Major facilitator Superfamily
K0V03_12780	COG0697	spore germination
K0V03_12785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K0V03_12795	COG2364	Membrane
K0V03_12800	COG1126	abc transporter atp-binding protein
K0V03_12805	COG0765	amino acid transport
K0V03_12810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K0V03_12815	COG0583	DNA-binding transcription factor activity
K0V03_12820	COG0163	prenyltransferase activity
K0V03_12825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
K0V03_12840	COG0596	Alpha beta hydrolase
K0V03_12845	COG3104	oligopeptide transport
K0V03_12850	COG5434	Belongs to the glycosyl hydrolase 28 family
K0V03_12860	COG0697	spore germination
K0V03_12870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K0V03_12875	COG1136	(ABC) transporter
K0V03_12880	COG0577	efflux transmembrane transporter activity
K0V03_12885	COG0745	RESPONSE REGULATOR receiver
K0V03_12890	COG5002	protein histidine kinase activity
K0V03_12890	COG3850	Histidine kinase
K0V03_12895	COG0457	Tetratricopeptide repeat
K0V03_12915	COG0527	aspartate kinase activity
K0V03_12920	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K0V03_12925	COG4605	iron ion homeostasis
K0V03_12930	COG4604	ABC transporter, ATP-binding protein
K0V03_12935	COG4607	ABC-type enterochelin transport system periplasmic component
K0V03_12940	COG2814	Major facilitator Superfamily
K0V03_12945	COG1309	transcriptional regulator
K0V03_12950	COG0778	Nitroreductase
K0V03_12955	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
K0V03_12960	COG0640	Transcriptional regulator
K0V03_12965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K0V03_12970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K0V03_12975	COG1012	belongs to the aldehyde dehydrogenase family
K0V03_12980	COG4975	Glucose uptake
K0V03_12985	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_12990	COG4549	nuclear export factor GLE1
K0V03_12995	COG1276	copper resistance
K0V03_12995	COG2372	response to copper ion
K0V03_13000	COG1349	DNA-binding transcription factor activity
K0V03_13010	COG2213	PTS system mannitol-specific
K0V03_13015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K0V03_13020	COG0246	Mannitol dehydrogenase
K0V03_13025	COG0473	3-isopropylmalate dehydrogenase activity
K0V03_13030	COG0681	Belongs to the peptidase S26 family
K0V03_13035	COG0412	Dienelactone hydrolase
K0V03_13040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K0V03_13050	COG0561	phosphatase activity
K0V03_13055	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K0V03_13060	COG1914	H( )-stimulated, divalent metal cation uptake system
K0V03_13065	COG4336	lyase activity
K0V03_13070	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K0V03_13075	COG1984	allophanate hydrolase subunit 2
K0V03_13080	COG1414	Transcriptional regulator
K0V03_13085	COG2755	lipolytic protein G-D-S-L family
K0V03_13095	COG2329	Antibiotic biosynthesis monooxygenase
K0V03_13100	COG0768	penicillin binding
K0V03_13105	COG4989	oxidoreductase activity
K0V03_13110	COG3711	transcriptional antiterminator
K0V03_13115	COG0318	PFAM AMP-dependent synthetase and ligase
K0V03_13120	COG2226	methyltransferase
K0V03_13125	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_13130	COG1917	Cupin 2, conserved barrel domain protein
K0V03_13135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K0V03_13140	COG3871	stress protein (general stress protein 26)
K0V03_13150	COG2814	Major facilitator Superfamily
K0V03_13155	COG1522	sequence-specific DNA binding
K0V03_13160	COG0551	DNA topoisomerase type I activity
K0V03_13160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K0V03_13165	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
K0V03_13170	COG3706	GGDEF domain
K0V03_13175	COG5298	Protein conserved in bacteria
K0V03_13180	COG1215	transferase activity, transferring glycosyl groups
K0V03_13190	COG0531	amino acid
K0V03_13195	COG0494	nUDIX hydrolase
K0V03_13200	COG0028	Belongs to the TPP enzyme family
K0V03_13225	COG1914	H( )-stimulated, divalent metal cation uptake system
K0V03_13230	COG2261	transglycosylase associated protein
K0V03_13235	COG4876	unkown
K0V03_13240	COG2217	Heavy metal translocating P-type atpase
K0V03_13245	COG3729	General stress protein
K0V03_13250	COG0662	Cupin 2, conserved barrel domain protein
K0V03_13255	COG2329	Antibiotic biosynthesis monooxygenase
K0V03_13260	COG3546	catalase activity
K0V03_13265	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K0V03_13270	COG3290	protein histidine kinase activity
K0V03_13275	COG4565	transcriptional regulatory protein
K0V03_13280	COG1301	dicarboxylic acid transport
K0V03_13285	COG0628	permease
K0V03_13290	COG1131	(ABC) transporter
K0V03_13295	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K0V03_13305	COG1960	acyl-CoA dehydrogenase activity
K0V03_13320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K0V03_13325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K0V03_13330	COG1181	Belongs to the D-alanine--D-alanine ligase family
K0V03_13335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K0V03_13340	COG0513	Belongs to the DEAD box helicase family
K0V03_13345	COG3402	PFAM membrane-flanked domain
K0V03_13350	COG3428	Bacterial PH domain
K0V03_13355	COG0705	Rhomboid family
K0V03_13360	COG0736	holo-[acyl-carrier-protein] synthase activity
K0V03_13365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K0V03_13370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K0V03_13375	COG0864	Transcriptional regulator
K0V03_13380	COG2337	Toxic component of a toxin-antitoxin (TA) module
K0V03_13385	COG1366	Belongs to the anti-sigma-factor antagonist family
K0V03_13390	COG1366	Belongs to the anti-sigma-factor antagonist family
K0V03_13395	COG2172	sigma factor antagonist activity
K0V03_13400	COG2208	phosphoserine phosphatase activity
K0V03_13405	COG1366	Belongs to the anti-sigma-factor antagonist family
K0V03_13410	COG2172	sigma factor antagonist activity
K0V03_13415	COG1191	sigma factor activity
K0V03_13420	COG2208	phosphoserine phosphatase activity
K0V03_13435	COG1673	EVE domain
K0V03_13440	COG1846	Transcriptional regulator
K0V03_13445	COG2183	response to ionizing radiation
K0V03_13455	COG3091	SprT-like family
K0V03_13495	COG0582	viral genome integration into host DNA
K0V03_13500	COG2856	Zn peptidase
K0V03_13505	COG1396	sequence-specific DNA binding
K0V03_13535	COG1674	ftsk spoiiie
K0V03_13540	COG2946	Replication initiation factor
K0V03_13575	COG3239	Fatty acid desaturase
K0V03_13585	COG1278	Cold shock
K0V03_13590	COG1329	Transcriptional regulator
K0V03_13600	COG1917	Cupin 2, conserved barrel domain protein
K0V03_13600	COG2207	Transcriptional regulator
K0V03_13605	COG0697	spore germination
K0V03_13610	COG2207	Transcriptional regulator
K0V03_13610	COG3708	Transcriptional regulator
K0V03_13615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K0V03_13620	COG0477	Major facilitator Superfamily
K0V03_13630	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
K0V03_13640	COG0697	spore germination
K0V03_13645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K0V03_13650	COG2030	dehydratase
K0V03_13655	COG3545	Serine hydrolase
K0V03_13660	COG1733	regulation of RNA biosynthetic process
K0V03_13665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K0V03_13670	COG0640	Transcriptional regulator
K0V03_13675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K0V03_13685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K0V03_13690	COG0697	spore germination
K0V03_13695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K0V03_13700	COG0076	glutamate decarboxylase activity
K0V03_13705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K0V03_13710	COG0640	Transcriptional regulator
K0V03_13715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K0V03_13730	COG4585	Histidine kinase
K0V03_13735	COG2197	response regulator
K0V03_13740	COG2409	Drug exporters of the RND superfamily
K0V03_13745	COG0596	Alpha beta hydrolase
K0V03_13750	COG1811	Na channel or pump
K0V03_13755	COG0789	Transcriptional regulator
K0V03_13755	COG4978	Transcriptional regulator
K0V03_13760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K0V03_13765	COG0778	Nitroreductase
K0V03_13770	COG0346	lactoylglutathione lyase activity
K0V03_13775	COG2259	Doxx family
K0V03_13780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K0V03_13795	COG2323	membrane
K0V03_13800	COG2323	membrane
K0V03_13805	COG0071	Belongs to the small heat shock protein (HSP20) family
K0V03_13820	COG1309	transcriptional regulator
K0V03_13830	COG0456	acetyltransferase
K0V03_13835	COG0488	(ABC) transporter
K0V03_13840	COG1113	amino acid transport
K0V03_13845	COG2318	DinB family
K0V03_13850	COG1846	Transcriptional regulator
K0V03_13855	COG1033	growth of symbiont in host cell
K0V03_13855	COG2409	Drug exporters of the RND superfamily
K0V03_13860	COG0778	Nitroreductase
K0V03_13865	COG1846	Transcriptional regulator
K0V03_13870	COG2814	Major facilitator Superfamily
K0V03_13875	COG0730	response to heat
K0V03_13880	COG1802	Transcriptional regulator
K0V03_13885	COG1388	LysM domain
K0V03_13885	COG3858	chitin binding
K0V03_13890	COG1819	glycosyl
K0V03_13900	COG1785	Belongs to the alkaline phosphatase family
K0V03_13905	COG5646	InterPro IPR014922
K0V03_13915	COG0454	-acetyltransferase
K0V03_13920	COG1078	dGTPase activity
K0V03_13925	COG1388	LysM domain
K0V03_13930	COG2814	Major facilitator Superfamily
K0V03_13935	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K0V03_13940	COG1447	Phosphotransferase system cellobiose-specific component IIA
K0V03_13945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K0V03_13950	COG2723	6-phospho-beta-galactosidase activity
K0V03_13955	COG2188	Transcriptional regulator
K0V03_13960	COG1940	carbohydrate kinase activity
K0V03_13965	COG1482	cell wall glycoprotein biosynthetic process
K0V03_13970	COG4124	Belongs to the glycosyl hydrolase 26 family
K0V03_14015	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K0V03_14020	COG0802	atpase or kinase
K0V03_14025	COG1214	PFAM Peptidase M22, glycoprotease
K0V03_14030	COG0456	acetyltransferase
K0V03_14035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K0V03_14040	COG0488	(ABC) transporter
K0V03_14045	COG0315	cyclic pyranopterin monophosphate synthase activity
K0V03_14050	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
K0V03_14055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K0V03_14060	COG0805	protein transport
K0V03_14070	COG1266	CAAX protease self-immunity
K0V03_14080	COG0459	protein refolding
K0V03_14085	COG4974	Belongs to the 'phage' integrase family
K0V03_14090	COG2856	Zn peptidase
K0V03_14105	COG1396	sequence-specific DNA binding
K0V03_14145	COG5377	YqaJ viral recombinase family
K0V03_14150	COG3723	Recombinational DNA repair protein, rece pathway
K0V03_14155	COG3935	DnaD domain protein
K0V03_14160	COG1484	DNA-dependent DNA replication
K0V03_14210	COG1595	DNA-templated transcription, initiation
K0V03_14235	COG5484	DNA packaging
K0V03_14310	COG5280	Phage tail tape measure protein TP901
K0V03_14310	COG3953	SLT domain
K0V03_14315	COG0791	NLP P60 protein
K0V03_14315	COG1388	LysM domain
K0V03_14380	COG1388	LysM domain
K0V03_14380	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_14380	COG5632	N-Acetylmuramoyl-L-alanine amidase
K0V03_14435	COG5444	nuclease activity
K0V03_14445	COG2322	membrane
K0V03_14460	COG0457	Tetratricopeptide repeat
K0V03_14465	COG1063	alcohol dehydrogenase
K0V03_14470	COG2211	Major facilitator Superfamily
K0V03_14475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K0V03_14480	COG1842	Phage shock protein A
K0V03_14485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K0V03_14490	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
K0V03_14495	COG4260	virion core protein, lumpy skin disease virus
K0V03_14505	COG2814	Major facilitator Superfamily
K0V03_14510	COG1063	alcohol dehydrogenase
K0V03_14515	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K0V03_14520	COG0823	Involved in the tonB-independent uptake of proteins
K0V03_14535	COG2267	carboxylic ester hydrolase activity
K0V03_14545	COG2132	Multicopper oxidase
K0V03_14550	COG1113	amino acid transport
K0V03_14560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K0V03_14565	COG0714	Associated with various cellular activities
K0V03_14570	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
K0V03_14575	COG1305	Transglutaminase-like
K0V03_14580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K0V03_14580	COG0519	Catalyzes the synthesis of GMP from XMP
K0V03_14595	COG2252	PERMEase
K0V03_14600	COG3064	Membrane
K0V03_14610	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
K0V03_14620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K0V03_14625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K0V03_14630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K0V03_14635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K0V03_14640	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K0V03_14645	COG0047	phosphoribosylformylglycinamidine synthase activity
K0V03_14650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K0V03_14655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K0V03_14660	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K0V03_14665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K0V03_14670	COG0138	bifunctional purine biosynthesis protein purh
K0V03_14675	COG0151	Belongs to the GarS family
K0V03_14680	COG1522	sequence-specific DNA binding
K0V03_14685	COG0531	amino acid
K0V03_14695	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K0V03_14700	COG1470	cell adhesion involved in biofilm formation
K0V03_14705	COG4496	protein, YerC YecD
K0V03_14715	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
K0V03_14720	COG0210	DNA helicase
K0V03_14725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K0V03_14730	COG4851	CamS sex pheromone cAM373 precursor
K0V03_14735	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K0V03_14740	COG1285	pathogenesis
K0V03_14745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K0V03_14750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K0V03_14755	COG0154	amidase activity
K0V03_14760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K0V03_14765	COG1309	transcriptional regulator
K0V03_14770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K0V03_14775	COG1597	lipid kinase activity
K0V03_14780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K0V03_14805	COG5444	nuclease activity
K0V03_14815	COG3586	endonuclease activity
K0V03_14825	COG0457	Tetratricopeptide repeat
K0V03_14835	COG0217	transcriptional regulatory protein
K0V03_14845	COG1309	transcriptional regulator
K0V03_14850	COG3631	Ketosteroid isomerase-related protein
K0V03_14855	COG0702	epimerase
K0V03_14870	COG3546	catalase activity
K0V03_14875	COG0454	-acetyltransferase
K0V03_14885	COG5578	integral membrane protein
K0V03_14890	COG2972	Histidine kinase
K0V03_14895	COG4753	response regulator
K0V03_14895	COG2207	Transcriptional regulator
K0V03_14900	COG1653	transport
K0V03_14905	COG1175	transmembrane transport
K0V03_14910	COG0395	ABC-type sugar transport system, permease component
K0V03_14915	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K0V03_14920	COG2207	Transcriptional regulator
K0V03_14925	COG2755	lipolytic protein G-D-S-L family
K0V03_14935	COG5578	integral membrane protein
K0V03_14940	COG3401	FG-GAP repeat protein
K0V03_14945	COG3401	FG-GAP repeat protein
K0V03_14950	COG2755	lipolytic protein G-D-S-L family
K0V03_14955	COG1874	Beta-galactosidase
K0V03_14965	COG1653	transport
K0V03_14970	COG4209	transmembrane transport
K0V03_14975	COG0395	ABC-type sugar transport system, permease component
K0V03_14980	COG1486	melibiose metabolic process
K0V03_14985	COG2323	membrane
K0V03_14990	COG2329	Antibiotic biosynthesis monooxygenase
K0V03_14995	COG0346	lactoylglutathione lyase activity
K0V03_15010	COG5583	Uncharacterized small protein (DUF2292)
K0V03_15015	COG0670	Belongs to the BI1 family
K0V03_15020	COG0697	spore germination
K0V03_15025	COG1846	Transcriptional regulator
K0V03_15030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K0V03_15045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K0V03_15045	COG2124	cytochrome p450
K0V03_15050	COG1368	sulfuric ester hydrolase activity
K0V03_15055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K0V03_15060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K0V03_15065	COG1442	glycosyl transferase family 8
K0V03_15070	COG1216	Glycosyl transferase, family 2
K0V03_15075	COG1442	glycosyl transferase family 8
K0V03_15080	COG2223	nitrite transmembrane transporter activity
K0V03_15085	COG1011	Hydrolase
K0V03_15090	COG0531	amino acid
K0V03_15095	COG1012	belongs to the aldehyde dehydrogenase family
K0V03_15100	COG0840	transmembrane signaling receptor activity
K0V03_15105	COG0488	(ABC) transporter
K0V03_15115	COG0789	Transcriptional regulator
K0V03_15120	COG2814	Major facilitator Superfamily
K0V03_15130	COG0488	(ABC) transporter
K0V03_15135	COG0513	Belongs to the DEAD box helicase family
K0V03_15140	COG0456	acetyltransferase
K0V03_15145	COG2130	NADP-dependent
K0V03_15150	COG1120	ATPase activity
K0V03_15155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K0V03_15160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K0V03_15165	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K0V03_15180	COG3866	Pectate lyase
K0V03_15185	COG0471	metal ion transport
K0V03_15190	COG3290	protein histidine kinase activity
K0V03_15195	COG4565	transcriptional regulatory protein
K0V03_15200	COG3181	Tripartite tricarboxylate transporter family receptor
K0V03_15205	COG2851	Citrate transporter
K0V03_15210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K0V03_15215	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
K0V03_15220	COG1254	Belongs to the acylphosphatase family
K0V03_15225	COG2258	MOSC domain
K0V03_15245	COG0024	Methionine aminopeptidase
K0V03_15250	COG1263	PTS System
K0V03_15250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K0V03_15255	COG1368	sulfuric ester hydrolase activity
K0V03_15270	COG1115	amino acid carrier protein
K0V03_15285	COG0697	spore germination
K0V03_15290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K0V03_15290	COG1263	PTS System
K0V03_15295	COG0366	Alpha amylase catalytic
K0V03_15300	COG2188	Transcriptional regulator
K0V03_15305	COG0778	Nitroreductase
K0V03_15310	COG0737	Belongs to the 5'-nucleotidase family
K0V03_15315	COG0693	protein deglycase activity
K0V03_15320	COG2814	Major facilitator Superfamily
K0V03_15325	COG4840	Belongs to the UPF0435 family
K0V03_15330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K0V03_15335	COG4980	gas vesicle protein
K0V03_15340	COG1295	ribonuclease BN
K0V03_15345	COG0477	Major facilitator Superfamily
K0V03_15350	COG0387	Pfam Sodium calcium exchanger
K0V03_15360	COG0668	transmembrane transport
K0V03_15365	COG0535	radical SAM domain protein
K0V03_15375	COG0726	polysaccharide deacetylase
K0V03_15380	COG2084	Dehydrogenase
K0V03_15385	COG0598	Magnesium transport protein CorA
K0V03_15390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K0V03_15395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K0V03_15405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K0V03_15410	COG4637	Psort location Cytoplasmic, score
K0V03_15420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K0V03_15425	COG0022	dehydrogenase e1 component
K0V03_15430	COG0508	dehydrogenase complex catalyzes the overall conversion of
K0V03_15435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K0V03_15440	COG3284	Transcriptional regulator
K0V03_15450	COG1742	UPF0060 membrane protein
K0V03_15475	COG4842	Belongs to the WXG100 family
K0V03_15490	COG5444	nuclease activity
K0V03_15505	COG1486	melibiose metabolic process
K0V03_15510	COG1737	Transcriptional regulator
K0V03_15515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K0V03_15515	COG1263	PTS System
K0V03_15520	COG5434	Belongs to the glycosyl hydrolase 28 family
K0V03_15525	COG1132	(ABC) transporter
K0V03_15530	COG1132	(ABC) transporter
K0V03_15535	COG2259	Doxx family
K0V03_15540	COG2514	catechol 2,3-dioxygenase activity
K0V03_15545	COG4585	Histidine kinase
K0V03_15550	COG2197	response regulator
K0V03_15555	COG1131	(ABC) transporter
K0V03_15560	COG0842	Transport permease protein
K0V03_15560	COG1511	domain protein
K0V03_15565	COG0842	Transport permease protein
K0V03_15570	COG1695	Transcriptional regulator
K0V03_15575	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
K0V03_15580	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
K0V03_15585	COG1309	transcriptional regulator
K0V03_15590	COG2814	Major facilitator Superfamily
K0V03_15595	COG2318	DinB family
K0V03_15600	COG2814	Major facilitator Superfamily
K0V03_15605	COG1846	Transcriptional regulator
K0V03_15610	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K0V03_15610	COG0392	lysyltransferase activity
K0V03_15615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K0V03_15620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K0V03_15625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K0V03_15630	COG0384	phenazine biosynthesis protein PhzF
K0V03_15635	COG0778	Nitroreductase
K0V03_15650	COG1090	epimerase
K0V03_15655	COG2137	regulation of response to DNA damage stimulus
K0V03_15665	COG2814	Major facilitator Superfamily
K0V03_15680	COG3103	Sh3 type 3 domain protein
K0V03_15685	COG5658	integral membrane protein
K0V03_15690	COG0596	Alpha beta hydrolase
K0V03_15695	COG0463	Glycosyl transferase, family 2
K0V03_15700	COG4485	Bacterial membrane protein, YfhO
K0V03_15705	COG1988	membrane-bound metal-dependent
K0V03_15710	COG1194	a g-specific adenine glycosylase
K0V03_15720	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_15735	COG3557	Belongs to the UPF0374 family
K0V03_15740	COG1132	(ABC) transporter
K0V03_15745	COG4129	membrane
K0V03_15750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K0V03_15755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K0V03_15760	COG0735	belongs to the Fur family
K0V03_15870	COG4326	sporulation control protein
K0V03_15880	COG5577	PFAM Coat F domain
K0V03_15885	COG3340	Belongs to the peptidase S51 family
K0V03_15890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K0V03_15900	COG0753	catalase activity
K0V03_15905	COG1116	anion transmembrane transporter activity
K0V03_15910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K0V03_15915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K0V03_15920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K0V03_15930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K0V03_15940	COG1476	TRANSCRIPTIONal
K0V03_15950	COG3382	B3 4 domain protein
K0V03_15955	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K0V03_15965	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K0V03_15970	COG0789	Transcriptional regulator
K0V03_15975	COG1664	Polymer-forming cytoskeletal
K0V03_15980	COG1664	Polymer-forming cytoskeletal
K0V03_15985	COG2766	serine protein kinase
K0V03_15990	COG2718	Belongs to the UPF0229 family
K0V03_15995	COG1846	Transcriptional regulator
K0V03_16000	COG1566	PFAM secretion protein HlyD family protein
K0V03_16005	COG2814	Major facilitator Superfamily
K0V03_16010	COG0655	NAD(P)H dehydrogenase (quinone) activity
K0V03_16030	COG1725	Transcriptional regulator
K0V03_16035	COG1131	(ABC) transporter
K0V03_16040	COG1131	(ABC) transporter
K0V03_16045	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K0V03_16050	COG1278	Cold shock
K0V03_16055	COG1464	Belongs to the NlpA lipoprotein family
K0V03_16060	COG3706	GGDEF domain
K0V03_16065	COG1823	symporter activity
K0V03_16095	COG5577	PFAM Coat F domain
K0V03_16100	COG4085	toxin activity
K0V03_16100	COG1525	nuclease
K0V03_16100	COG0737	Belongs to the 5'-nucleotidase family
K0V03_16105	COG3764	Sortase (surface protein transpeptidase)
K0V03_16110	COG0564	pseudouridine synthase activity
K0V03_16120	COG0517	IMP dehydrogenase activity
K0V03_16125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K0V03_16130	COG3153	acetyltransferase
K0V03_16130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K0V03_16135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K0V03_16140	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K0V03_16145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K0V03_16150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K0V03_16155	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K0V03_16160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K0V03_16165	COG2203	Gaf domain
K0V03_16165	COG4585	Histidine kinase
K0V03_16170	COG2197	response regulator
K0V03_16175	COG0431	NADPH-dependent FMN reductase
K0V03_16190	COG1388	LysM domain
K0V03_16190	COG0791	NLP P60 protein
K0V03_16195	COG1959	2 iron, 2 sulfur cluster binding
K0V03_16200	COG0668	transmembrane transport
K0V03_16205	COG2719	SpoVR family
K0V03_16210	COG1785	Belongs to the alkaline phosphatase family
K0V03_16215	COG0791	NLP P60 protein
K0V03_16215	COG1388	LysM domain
K0V03_16220	COG0583	DNA-binding transcription factor activity
K0V03_16225	COG0372	Belongs to the citrate synthase family
K0V03_16230	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_16235	COG0531	amino acid
K0V03_16240	COG0733	neurotransmitter:sodium symporter activity
K0V03_16245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K0V03_16250	COG0456	acetyltransferase
K0V03_16265	COG1595	DNA-templated transcription, initiation
K0V03_16270	COG0667	Aldo Keto reductase
K0V03_16275	COG0204	Acyl-transferase
K0V03_16280	COG1253	flavin adenine dinucleotide binding
K0V03_16285	COG0789	Transcriptional regulator
K0V03_16290	COG0436	Aminotransferase
K0V03_16295	COG1253	flavin adenine dinucleotide binding
K0V03_16300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K0V03_16305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K0V03_16310	COG0584	glycerophosphoryl diester phosphodiesterase
K0V03_16320	COG0668	transmembrane transport
K0V03_16325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K0V03_16330	COG0726	polysaccharide deacetylase
K0V03_16335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K0V03_16340	COG1757	Na H antiporter
K0V03_16345	COG0589	response to stress
K0V03_16355	COG1132	(ABC) transporter
K0V03_16360	COG1132	(ABC) transporter
K0V03_16365	COG0702	epimerase
K0V03_16385	COG0189	ligase activity
K0V03_16390	COG0189	ligase activity
K0V03_16395	COG4399	Belongs to the UPF0754 family
K0V03_16400	COG3679	Belongs to the UPF0342 family
K0V03_16405	COG4335	DNA alkylation repair
K0V03_16410	COG0561	phosphatase activity
K0V03_16415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K0V03_16420	COG0475	glutathione-regulated potassium exporter activity
K0V03_16425	COG0490	domain, Protein
K0V03_16435	COG1024	Enoyl-CoA hydratase
K0V03_16445	COG4152	abc transporter atp-binding protein
K0V03_16450	COG1668	transmembrane transport
K0V03_16455	COG0420	3'-5' exonuclease activity
K0V03_16460	COG4717	serine-type aminopeptidase activity
K0V03_16465	COG3481	metal-dependent phosphohydrolase, HD sub domain
K0V03_16475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K0V03_16505	COG1846	Transcriptional regulator
K0V03_16510	COG4980	gas vesicle protein
K0V03_16525	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K0V03_16530	COG0537	adenosine 5'-monophosphoramidase activity
K0V03_16535	COG1131	(ABC) transporter
K0V03_16540	COG4473	ABC transporter
K0V03_16550	COG1473	amidohydrolase
K0V03_16555	COG3069	C4-dicarboxylate transmembrane transporter activity
K0V03_16565	COG2329	Antibiotic biosynthesis monooxygenase
K0V03_16570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K0V03_16575	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K0V03_16580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K0V03_16585	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K0V03_16590	COG1309	transcriptional regulator
K0V03_16595	COG1511	domain protein
K0V03_16600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K0V03_16605	COG4377	Putative membrane peptidase family (DUF2324)
K0V03_16615	COG1363	Peptidase, m42
K0V03_16620	COG4405	Protein conserved in bacteria
K0V03_16625	COG1301	dicarboxylic acid transport
K0V03_16635	COG1234	tRNA 3'-trailer cleavage
K0V03_16640	COG0095	Lipoate-protein ligase
K0V03_16645	COG0702	epimerase
K0V03_16650	COG0318	PFAM AMP-dependent synthetase and ligase
K0V03_16660	COG0501	Belongs to the peptidase M48B family
K0V03_16670	COG0456	acetyltransferase
K0V03_16675	COG0604	alcohol dehydrogenase
K0V03_16680	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K0V03_16685	COG0406	alpha-ribazole phosphatase activity
K0V03_16690	COG0183	Belongs to the thiolase family
K0V03_16695	COG0318	PFAM AMP-dependent synthetase and ligase
K0V03_16700	COG1268	BioY protein
K0V03_16705	COG0840	transmembrane signaling receptor activity
K0V03_16710	COG0723	plastoquinol--plastocyanin reductase activity
K0V03_16710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K0V03_16715	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_16725	COG4903	ComK protein
K0V03_16730	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_16740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K0V03_16755	COG0398	Pfam SNARE associated Golgi protein
K0V03_16760	COG0681	Belongs to the peptidase S26 family
K0V03_16765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K0V03_16770	COG1846	Transcriptional regulator
K0V03_16775	COG0738	Major facilitator superfamily
K0V03_16780	COG0673	inositol 2-dehydrogenase activity
K0V03_16785	COG0561	phosphatase activity
K0V03_16790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K0V03_16795	COG1609	Transcriptional regulator
K0V03_16800	COG3180	Ammonia monooxygenase
K0V03_16805	COG0477	Major facilitator Superfamily
K0V03_16805	COG2814	Major facilitator Superfamily
K0V03_16810	COG4533	DNA binding
K0V03_16820	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K0V03_16825	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
K0V03_16830	COG1074	ATP-dependent DNA helicase activity
K0V03_16835	COG0420	3'-5' exonuclease activity
K0V03_16840	COG0419	ATPase involved in DNA repair
K0V03_16845	COG1403	HNH endonuclease
K0V03_16885	COG5337	Spore coat protein CotH
K0V03_16890	COG0179	Fumarylacetoacetate (FAA) hydrolase
K0V03_16900	COG1404	Belongs to the peptidase S8 family
K0V03_16910	COG0367	asparagine synthase
K0V03_16915	COG2318	DinB family
K0V03_16920	COG1562	ergosterol biosynthetic process
K0V03_16925	COG0534	Mate efflux family protein
K0V03_16930	COG1917	Cupin 2, conserved barrel domain protein
K0V03_16930	COG2207	Transcriptional regulator
K0V03_16935	COG1609	Transcriptional regulator
K0V03_16940	COG0673	inositol 2-dehydrogenase activity
K0V03_16945	COG2318	DinB family
K0V03_16950	COG1279	arginine transmembrane transporter activity
K0V03_16955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K0V03_16960	COG1357	PFAM Pentapeptide repeats (8 copies)
K0V03_16965	COG2267	carboxylic ester hydrolase activity
K0V03_16970	COG0529	Catalyzes the synthesis of activated sulfate
K0V03_16975	COG2046	Belongs to the sulfate adenylyltransferase family
K0V03_16980	COG0175	sulfate reduction
K0V03_16985	COG2045	Belongs to the ComB family
K0V03_16990	COG1809	phosphosulfolactate synthase activity
K0V03_16995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K0V03_17000	COG4948	Mandelate Racemase Muconate Lactonizing
K0V03_17005	COG2814	Major facilitator Superfamily
K0V03_17010	COG0454	-acetyltransferase
K0V03_17015	COG2153	protein acetylation
K0V03_17020	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K0V03_17020	COG0646	methionine synthase
K0V03_17025	COG1666	GTP binding
K0V03_17030	COG2996	Protein conserved in bacteria
K0V03_17050	COG1695	Transcriptional regulator
K0V03_17065	COG3227	Zinc metalloprotease (Elastase)
K0V03_17070	COG1307	EDD domain protein, DegV family
K0V03_17075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K0V03_17095	COG0561	phosphatase activity
K0V03_17100	COG1073	alpha beta
K0V03_17105	COG2151	metal-sulfur cluster biosynthetic enzyme
K0V03_17115	COG0277	FAD linked oxidase domain protein
K0V03_17120	COG2271	Major facilitator Superfamily
K0V03_17125	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K0V03_17130	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K0V03_17140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K0V03_17145	COG0505	Belongs to the CarA family
K0V03_17150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K0V03_17155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K0V03_17170	COG2267	carboxylic ester hydrolase activity
K0V03_17180	COG1744	ABC transporter substrate-binding protein PnrA-like
K0V03_17195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K0V03_17200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K0V03_17205	COG5504	Zn-dependent protease
K0V03_17210	COG0444	Belongs to the ABC transporter superfamily
K0V03_17215	COG4608	Belongs to the ABC transporter superfamily
K0V03_17225	COG0601	transmembrane transport
K0V03_17230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K0V03_17240	COG0180	Tryptophanyl-tRNA synthetase
K0V03_17245	COG4166	transmembrane transport
K0V03_17250	COG0601	transmembrane transport
K0V03_17255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K0V03_17260	COG0444	Belongs to the ABC transporter superfamily
K0V03_17265	COG4608	Belongs to the ABC transporter superfamily
K0V03_17270	COG2814	Major facilitator Superfamily
K0V03_17275	COG0456	acetyltransferase
K0V03_17280	COG1393	Belongs to the ArsC family
K0V03_17285	COG0861	Integral membrane protein TerC family
K0V03_17295	COG4862	establishment of competence for transformation
K0V03_17305	COG4469	Competence protein
K0V03_17310	COG1164	Oligoendopeptidase f
K0V03_17320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K0V03_17325	COG2346	COG2346, Truncated hemoglobins
K0V03_17330	COG0741	lytic transglycosylase activity
K0V03_17335	COG4116	CYTH
K0V03_17345	COG2357	RelA SpoT domain protein
K0V03_17350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K0V03_17355	COG0564	pseudouridine synthase activity
K0V03_17360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K0V03_17365	COG0569	domain protein
K0V03_17365	COG0475	glutathione-regulated potassium exporter activity
K0V03_17370	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K0V03_17375	COG0352	thiamine-phosphate diphosphorylase activity
K0V03_17380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K0V03_17385	COG2104	thiamine diphosphate biosynthetic process
K0V03_17390	COG2022	thiamine diphosphate biosynthetic process
K0V03_17395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K0V03_17400	COG0351	phosphomethylpyrimidine kinase
K0V03_17405	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K0V03_17460	COG0210	DNA helicase
K0V03_17470	COG2153	protein acetylation
K0V03_17475	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K0V03_17480	COG2382	esterase
K0V03_17485	COG0626	cystathionine gamma-synthase activity
K0V03_17490	COG0626	cystathionine gamma-synthase activity
K0V03_17500	COG5505	Protein of unknown function (DUF819)
K0V03_17530	COG1396	sequence-specific DNA binding
K0V03_17685	COG0457	Tetratricopeptide repeat
K0V03_17690	COG5444	nuclease activity
K0V03_17755	COG3711	transcriptional antiterminator
K0V03_17755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K0V03_17760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K0V03_17760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K0V03_17760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K0V03_17765	COG1482	cell wall glycoprotein biosynthetic process
K0V03_17775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K0V03_17785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K0V03_17800	COG0109	protoheme IX farnesyltransferase activity
K0V03_17810	COG0726	polysaccharide deacetylase
K0V03_17830	COG2205	protein histidine kinase activity
K0V03_17840	COG3383	formate dehydrogenase (NAD+) activity
K0V03_17845	COG2427	Protein of unknown function (DUF1641)
K0V03_17855	COG1051	belongs to the nudix hydrolase family
K0V03_17865	COG2124	cytochrome p450
K0V03_17870	COG1819	glycosyl
K0V03_17880	COG1587	Uroporphyrinogen-III synthase
K0V03_17885	COG0390	transport system, permease component
K0V03_17890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K0V03_17895	COG0697	spore germination
K0V03_17900	COG4297	protein containing double-stranded beta helix domain
K0V03_17910	COG1252	NADH dehydrogenase
K0V03_17915	COG1904	glucuronate isomerase
K0V03_17920	COG2211	Major facilitator Superfamily
K0V03_17925	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
K0V03_17930	COG1063	alcohol dehydrogenase
K0V03_17935	COG1312	Catalyzes the dehydration of D-mannonate
K0V03_17940	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_17945	COG2271	Major facilitator Superfamily
K0V03_17950	COG1609	Transcriptional regulator
K0V03_17955	COG0246	Mannitol dehydrogenase
K0V03_17960	COG2721	sulfolactate sulfo-lyase activity
K0V03_17965	COG0730	response to heat
K0V03_17970	COG2318	DinB family
K0V03_17975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K0V03_17980	COG0457	Tetratricopeptide repeat
K0V03_17990	COG2350	Protein conserved in bacteria
K0V03_17995	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_17995	COG1388	LysM domain
K0V03_17995	COG5632	N-Acetylmuramoyl-L-alanine amidase
K0V03_18005	COG4195	phage-related replication protein
K0V03_18010	COG3546	catalase activity
K0V03_18015	COG2856	Zn peptidase
K0V03_18020	COG1396	sequence-specific DNA binding
K0V03_18030	COG1522	sequence-specific DNA binding
K0V03_18035	COG1484	DNA-dependent DNA replication
K0V03_18055	COG1595	DNA-templated transcription, initiation
K0V03_18060	COG5484	DNA packaging
K0V03_18060	COG3728	DNA packaging
K0V03_18065	COG1783	phage Terminase large subunit
K0V03_18070	COG5518	Phage portal protein
K0V03_18075	COG0338	D12 class N6 adenine-specific DNA methyltransferase
K0V03_18080	COG4653	Phage capsid family
K0V03_18130	COG5412	phage tail tape measure protein
K0V03_18130	COG3953	SLT domain
K0V03_18130	COG5412	phage tail tape measure protein
K0V03_18130	COG3953	SLT domain
K0V03_18135	COG1652	LysM domain
K0V03_18140	COG4193	domain, Protein
K0V03_18150	COG3628	GPW Gp25 family protein
K0V03_18155	COG3299	homolog of phage Mu protein gp47
K0V03_18160	COG3778	Protein conserved in bacteria
K0V03_18200	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_18200	COG5632	N-Acetylmuramoyl-L-alanine amidase
K0V03_18220	COG0306	phosphate transporter
K0V03_18225	COG1392	Phosphate transport regulator
K0V03_18230	COG0531	amino acid
K0V03_18235	COG0346	lactoylglutathione lyase activity
K0V03_18240	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K0V03_18245	COG0463	Glycosyl transferase, family 2
K0V03_18255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K0V03_18260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K0V03_18265	COG2362	D-Aminopeptidase
K0V03_18270	COG0601	transmembrane transport
K0V03_18275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K0V03_18280	COG0444	Belongs to the ABC transporter superfamily
K0V03_18285	COG4166	transmembrane transport
K0V03_18290	COG1619	proteins homologs of microcin C7 resistance protein MccF
K0V03_18295	COG4948	Mandelate Racemase Muconate Lactonizing
K0V03_18300	COG0791	NLP P60 protein
K0V03_18305	COG4608	Belongs to the ABC transporter superfamily
K0V03_18310	COG2706	6-phosphogluconolactonase activity
K0V03_18315	COG1834	amidinotransferase
K0V03_18320	COG1607	acyl-coa hydrolase
K0V03_18325	COG1017	nitric oxide dioxygenase activity
K0V03_18325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K0V03_18335	COG2323	membrane
K0V03_18340	COG2318	DinB family
K0V03_18345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K0V03_18350	COG2076	Multidrug Resistance protein
K0V03_18355	COG2076	Multidrug Resistance protein
K0V03_18360	COG0788	formyltetrahydrofolate deformylase activity
K0V03_18365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K0V03_18370	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K0V03_18375	COG1764	response to oxidative stress
K0V03_18380	COG1846	Transcriptional regulator
K0V03_18385	COG1764	response to oxidative stress
K0V03_18395	COG0590	tRNA wobble adenosine to inosine editing
K0V03_18400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
K0V03_18405	COG1404	Belongs to the peptidase S8 family
K0V03_18410	COG1366	Belongs to the anti-sigma-factor antagonist family
K0V03_18415	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K0V03_18420	COG1122	ATPase activity
K0V03_18425	COG4721	ABC-type cobalt transport system, permease component
K0V03_18435	COG0745	RESPONSE REGULATOR receiver
K0V03_18440	COG3850	Histidine kinase
K0V03_18440	COG5002	protein histidine kinase activity
K0V03_18445	COG3212	peptidase
K0V03_18450	COG3212	peptidase
K0V03_18460	COG2239	Acts as a magnesium transporter
K0V03_18465	COG0789	Transcriptional regulator
K0V03_18480	COG1846	Transcriptional regulator
K0V03_18485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K0V03_18490	COG0726	polysaccharide deacetylase
K0V03_18495	COG1408	metallophosphoesterase
K0V03_18505	COG0463	Glycosyl transferase, family 2
K0V03_18510	COG1793	dna ligase
K0V03_18510	COG3285	dna ligase
K0V03_18515	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
K0V03_18520	COG3300	MHYT domain
K0V03_18520	COG5001	Diguanylate cyclase
K0V03_18525	COG0586	Pfam SNARE associated Golgi protein
K0V03_18530	COG0861	Integral membrane protein TerC family
K0V03_18535	COG1191	sigma factor activity
K0V03_18555	COG0501	Belongs to the peptidase M48B family
K0V03_18560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K0V03_18575	COG3594	Acyltransferase
K0V03_18580	COG5002	protein histidine kinase activity
K0V03_18585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K0V03_18595	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K0V03_18600	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
K0V03_18605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K0V03_18610	COG0436	Aminotransferase
K0V03_18615	COG1850	ribulose-bisphosphate carboxylase activity
K0V03_18620	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
K0V03_18625	COG0235	Class ii aldolase
K0V03_18630	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
K0V03_18635	COG3339	Conserved Protein
K0V03_18650	COG3852	Histidine kinase
K0V03_18655	COG1846	Transcriptional regulator
K0V03_18660	COG1360	Flagellar Motor Protein
K0V03_18665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K0V03_18670	COG0542	response to heat
K0V03_18675	COG3949	Membrane
K0V03_18680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K0V03_18685	COG0720	synthase
K0V03_18690	COG0602	queuosine metabolic process
K0V03_18695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K0V03_18700	COG1733	regulation of RNA biosynthetic process
K0V03_18705	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_18725	COG4873	Protein conserved in bacteria
K0V03_18735	COG3773	Cell wall hydrolase
K0V03_18740	COG2244	polysaccharide biosynthetic process
K0V03_18745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K0V03_18750	COG2217	Heavy metal translocating P-type atpase
K0V03_18760	COG0006	proline dipeptidase activity
K0V03_18765	COG1609	Transcriptional regulator
K0V03_18770	COG3711	transcriptional antiterminator
K0V03_18775	COG1263	PTS System
K0V03_18775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K0V03_18775	COG2190	(PTS) system
K0V03_18780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K0V03_18785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K0V03_18795	COG1533	DNA photolyase activity
K0V03_18800	COG0456	acetyltransferase
K0V03_18805	COG0840	transmembrane signaling receptor activity
K0V03_18810	COG2084	Dehydrogenase
K0V03_18815	COG4257	antibiotic catabolic process
K0V03_18820	COG2340	Cysteine-rich secretory protein family
K0V03_18825	COG0768	penicillin binding
K0V03_18830	COG4191	Histidine kinase
K0V03_18835	COG0436	Aminotransferase
K0V03_18845	COG0784	Response regulator, receiver
K0V03_18845	COG0835	chemotaxis
K0V03_18855	COG2814	Major facilitator Superfamily
K0V03_18860	COG1376	ErfK ybiS ycfS ynhG family protein
K0V03_18865	COG1408	metallophosphoesterase
K0V03_18870	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_18875	COG2200	EAL domain
K0V03_18880	COG4703	Protein of unknown function (DUF1797)
K0V03_18885	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
K0V03_18895	COG0517	IMP dehydrogenase activity
K0V03_18900	COG0583	DNA-binding transcription factor activity
K0V03_18905	COG0716	FMN binding
K0V03_18915	COG0716	FMN binding
K0V03_18920	COG2171	N-acyltransferase activity
K0V03_18925	COG1473	amidohydrolase
K0V03_18935	COG0668	transmembrane transport
K0V03_18940	COG0450	alkyl hydroperoxide reductase
K0V03_18945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K0V03_18960	COG0746	molybdenum cofactor guanylyltransferase activity
K0V03_18965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K0V03_18970	COG0303	'Molybdopterin
K0V03_18975	COG1763	Mo-molybdopterin cofactor biosynthetic process
K0V03_18980	COG0314	molybdopterin synthase activity
K0V03_18985	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K0V03_18990	COG1132	(ABC) transporter
K0V03_18995	COG1132	(ABC) transporter
K0V03_19005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K0V03_19010	COG1136	(ABC) transporter
K0V03_19015	COG0577	efflux transmembrane transporter activity
K0V03_19020	COG1349	DNA-binding transcription factor activity
K0V03_19025	COG1105	Belongs to the carbohydrate kinase PfkB family
K0V03_19030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K0V03_19030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K0V03_19030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K0V03_19035	COG0681	Belongs to the peptidase S26 family
K0V03_19045	COG0488	(ABC) transporter
K0V03_19050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K0V03_19055	COG2309	aminopeptidase activity
K0V03_19065	COG1077	Cell shape determining protein MreB Mrl
K0V03_19070	COG2002	toxin-antitoxin pair type II binding
K0V03_19075	COG3852	Histidine kinase
K0V03_19080	COG2105	PFAM AIG2 family protein
K0V03_19080	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
K0V03_19085	COG0569	domain protein
K0V03_19090	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K0V03_19095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K0V03_19100	COG5503	Protein of unknown function (DUF1447)
K0V03_19105	COG0561	phosphatase activity
K0V03_19110	COG0242	peptide deformylase activity
K0V03_19120	COG0497	DNA recombination
K0V03_19125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K0V03_19130	COG0022	dehydrogenase e1 component
K0V03_19135	COG0508	dehydrogenase complex catalyzes the overall conversion of
K0V03_19140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K0V03_19145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K0V03_19155	COG1982	Orn Lys Arg decarboxylase major
K0V03_19160	COG4476	Belongs to the UPF0223 family
K0V03_19165	COG4493	Belongs to the UPF0637 family
K0V03_19175	COG0483	inositol monophosphate 1-phosphatase activity
K0V03_19185	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K0V03_19205	COG1595	DNA-templated transcription, initiation
K0V03_19225	COG1217	gtp-binding protein TYPA
K0V03_19235	COG4896	Protein conserved in bacteria
K0V03_19245	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K0V03_19250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K0V03_19255	COG2066	Belongs to the glutaminase family
K0V03_19260	COG4838	Belongs to the UPF0358 family
K0V03_19265	COG0772	Belongs to the SEDS family
K0V03_19270	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K0V03_19275	COG1612	heme a metabolic process
K0V03_19280	COG0109	protoheme IX farnesyltransferase activity
K0V03_19285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K0V03_19285	COG2010	Cytochrome c
K0V03_19290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K0V03_19295	COG1845	cytochrome c oxidase, subunit III
K0V03_19300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K0V03_19305	COG3336	cytochrome c oxidase
K0V03_19315	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
K0V03_19320	COG2340	Cysteine-rich secretory protein family
K0V03_19335	COG3679	Belongs to the UPF0342 family
K0V03_19340	COG4471	UPF0298 protein
K0V03_19345	COG0742	ribosomal rna small subunit methyltransferase
K0V03_19350	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K0V03_19355	COG3314	Sporulation integral membrane protein YlbJ
K0V03_19360	COG1752	Esterase of the alpha-beta hydrolase superfamily
K0V03_19365	COG3480	Lon protease (S16) C-terminal proteolytic domain
K0V03_19370	COG1323	Belongs to the UPF0348 family
K0V03_19380	COG1399	metal-binding, possibly nucleic acid-binding protein
K0V03_19395	COG0454	-acetyltransferase
K0V03_19400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K0V03_19405	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
K0V03_19410	COG2001	Belongs to the MraZ family
K0V03_19415	COG0275	rRNA processing
K0V03_19420	COG4839	cell division protein FtsL
K0V03_19425	COG0768	penicillin binding
K0V03_19430	COG0768	penicillin binding
K0V03_19435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K0V03_19440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K0V03_19445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K0V03_19450	COG0772	Belongs to the SEDS family
K0V03_19455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K0V03_19460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K0V03_19465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K0V03_19470	COG3879	Bacterial protein of unknown function (DUF881)
K0V03_19475	COG3879	Bacterial protein of unknown function (DUF881)
K0V03_19480	COG3856	small basic protein
K0V03_19485	COG0849	cell division
K0V03_19490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K0V03_19505	COG1191	sigma factor activity
K0V03_19510	COG1191	sigma factor activity
K0V03_19515	COG1119	ATPase activity
K0V03_19520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K0V03_19525	COG1873	PFAM PRC-barrel domain
K0V03_19530	COG1496	oxidoreductase activity
K0V03_19535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K0V03_19540	COG1799	cell septum assembly
K0V03_19545	COG0762	integral membrane protein
K0V03_19550	COG2302	S4 RNA-binding domain
K0V03_19555	COG3599	regulation of cell shape
K0V03_19560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K0V03_19565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K0V03_19570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K0V03_19575	COG0564	pseudouridine synthase activity
K0V03_19580	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
K0V03_19585	COG2233	PERMEase
K0V03_19590	COG0540	Belongs to the ATCase OTCase family
K0V03_19595	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K0V03_19600	COG0505	Belongs to the CarA family
K0V03_19605	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K0V03_19610	COG0543	2 iron, 2 sulfur cluster binding
K0V03_19615	COG0167	dihydroorotate dehydrogenase activity
K0V03_19620	COG0284	orotidine-5'-phosphate decarboxylase activity
K0V03_19625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K0V03_19630	COG0175	sulfate reduction
K0V03_19635	COG0306	phosphate transporter
K0V03_19640	COG2046	Belongs to the sulfate adenylyltransferase family
K0V03_19645	COG0529	Catalyzes the synthesis of activated sulfate
K0V03_19650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K0V03_19655	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
K0V03_19660	COG1648	precorrin-2 dehydrogenase activity
K0V03_19665	COG1293	RNA-binding protein homologous to eukaryotic snRNP
K0V03_19670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K0V03_19675	COG1561	YicC-like family, N-terminal region
K0V03_19685	COG0194	GDP metabolic process
K0V03_19690	COG1758	RNA polymerase activity
K0V03_19695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K0V03_19700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K0V03_19705	COG0242	peptide deformylase activity
K0V03_19710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K0V03_19715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K0V03_19715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K0V03_19720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K0V03_19725	COG0631	protein serine/threonine phosphatase activity
K0V03_19730	COG2815	serine threonine protein kinase
K0V03_19730	COG0515	serine threonine protein kinase
K0V03_19735	COG1162	GTPase activity
K0V03_19740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K0V03_19745	COG1564	THIamine pyrophosphokinase
K0V03_19755	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K0V03_19760	COG1302	Protein conserved in bacteria
K0V03_19765	COG1461	Dihydroxyacetone kinase
K0V03_19770	COG1760	l-serine dehydratase
K0V03_19775	COG1760	l-serine dehydratase
K0V03_19780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K0V03_19785	COG1349	DNA-binding transcription factor activity
K0V03_19785	COG2050	protein possibly involved in aromatic compounds catabolism
K0V03_19790	COG0416	fatty acid biosynthetic process
K0V03_19795	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K0V03_19800	COG1028	Short-chain dehydrogenase reductase Sdr
K0V03_19810	COG0571	ribonuclease III activity
K0V03_19815	COG1196	nuclear chromosome segregation
K0V03_19820	COG0552	protein localization to endoplasmic reticulum
K0V03_19830	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
K0V03_19835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K0V03_19840	COG0228	four-way junction DNA binding
K0V03_19845	COG1837	Belongs to the UPF0109 family
K0V03_19855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K0V03_19860	COG0336	Belongs to the RNA methyltransferase TrmD family
K0V03_19865	COG0335	large ribosomal subunit rRNA binding
K0V03_19870	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K0V03_19875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K0V03_19885	COG2257	FlhB HrpN YscU SpaS Family
K0V03_19890	COG0045	succinate-CoA ligase (ADP-forming) activity
K0V03_19895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K0V03_19900	COG0758	DNA mediated transformation
K0V03_19905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K0V03_19910	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
K0V03_19915	COG4974	Belongs to the 'phage' integrase family
K0V03_19920	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K0V03_19925	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K0V03_19930	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
K0V03_19935	COG1815	bacterial-type flagellum-dependent cell motility
K0V03_19940	COG1558	bacterial-type flagellum-dependent cell motility
K0V03_19945	COG1677	Flagellar hook-basal body complex protein FliE
K0V03_19950	COG1766	The M ring may be actively involved in energy transduction
K0V03_19955	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K0V03_19960	COG1317	bacterial-type flagellum organization
K0V03_19965	COG1157	protein secretion by the type III secretion system
K0V03_19970	COG2882	bacterial-type flagellum organization
K0V03_19975	COG3334	PFAM MgtE intracellular
K0V03_19980	COG3144	bacterial-type flagellum assembly
K0V03_19985	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
K0V03_19990	COG4786	Flagellar basal body rod
K0V03_19995	COG1582	Flagellar protein (FlbD)
K0V03_20000	COG1580	Controls the rotational direction of flagella during chemotaxis
K0V03_20005	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K0V03_20010	COG1776	CheC inhibitor of MCP methylation
K0V03_20010	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K0V03_20015	COG2201	protein-glutamate methylesterase activity
K0V03_20020	COG3190	flagellar
K0V03_20025	COG1338	Plays a role in the flagellum-specific transport system
K0V03_20030	COG1987	bacterial-type flagellum assembly
K0V03_20035	COG1684	flagellar biosynthetic protein fliR
K0V03_20040	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K0V03_20045	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K0V03_20050	COG1419	protein localization to endoplasmic reticulum
K0V03_20055	COG0455	bacterial-type flagellum organization
K0V03_20060	COG2201	protein-glutamate methylesterase activity
K0V03_20065	COG0643	Histidine kinase
K0V03_20065	COG2198	Histidine kinase
K0V03_20070	COG0835	chemotaxis
K0V03_20075	COG1776	CheC inhibitor of MCP methylation
K0V03_20080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
K0V03_20085	COG1191	sigma factor activity
K0V03_20095	COG0052	Belongs to the universal ribosomal protein uS2 family
K0V03_20100	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K0V03_20105	COG0528	UMP kinase activity
K0V03_20110	COG0233	cytoplasmic translational termination
K0V03_20115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K0V03_20120	COG4589	Belongs to the CDS family
K0V03_20125	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K0V03_20130	COG0750	zinc metalloprotease
K0V03_20135	COG0442	prolyl-tRNA aminoacylation
K0V03_20140	COG2176	DNA-directed DNA polymerase activity
K0V03_20145	COG0779	Required for maturation of 30S ribosomal subunits
K0V03_20150	COG0195	Participates in both transcription termination and antitermination
K0V03_20155	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K0V03_20160	COG1358	cellular component organization or biogenesis
K0V03_20165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K0V03_20170	COG1550	Protein conserved in bacteria
K0V03_20175	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K0V03_20180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K0V03_20185	COG0196	riboflavin kinase activity
K0V03_20190	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K0V03_20195	COG1185	polyribonucleotide nucleotidyltransferase activity
K0V03_20200	COG0726	polysaccharide deacetylase
K0V03_20205	COG0612	Peptidase, M16
K0V03_20210	COG1873	PFAM PRC-barrel domain
K0V03_20215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K0V03_20220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K0V03_20225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K0V03_20230	COG0527	aspartate kinase activity
K0V03_20235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K0V03_20240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K0V03_20245	COG0740	serine-type endopeptidase activity
K0V03_20255	COG4980	gas vesicle protein
K0V03_20255	COG1674	ftsk spoiiie
K0V03_20260	COG2188	Transcriptional regulator
K0V03_20265	COG2814	Major facilitator Superfamily
K0V03_20270	COG0612	Peptidase, M16
K0V03_20275	COG0612	Peptidase, M16
K0V03_20280	COG0300	oxidoreductase activity
K0V03_20295	COG1426	Protein conserved in bacteria
K0V03_20300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K0V03_20305	COG1058	Belongs to the CinA family
K0V03_20305	COG1546	Belongs to the CinA family
K0V03_20310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K0V03_20315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K0V03_20320	COG1418	mRNA catabolic process
K0V03_20325	COG1692	metallophosphoesterase
K0V03_20330	COG2359	stage V sporulation protein S
K0V03_20335	COG1063	alcohol dehydrogenase
K0V03_20340	COG0156	8-amino-7-oxononanoate synthase activity
K0V03_20345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K0V03_20350	COG4550	Control of competence regulator ComK, YlbF/YmcA
K0V03_20360	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K0V03_20365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K0V03_20380	COG3226	Transcriptional regulator
K0V03_20390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K0V03_20395	COG1404	Belongs to the peptidase S8 family
K0V03_20405	COG4195	phage-related replication protein
K0V03_20410	COG1764	response to oxidative stress
K0V03_20415	COG2076	Multidrug Resistance protein
K0V03_20420	COG2076	Multidrug Resistance protein
K0V03_20435	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K0V03_20440	COG1923	regulation of RNA biosynthetic process
K0V03_20455	COG1780	Probably involved in ribonucleotide reductase function
K0V03_20460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K0V03_20465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K0V03_20470	COG4112	unkown
K0V03_20475	COG0860	N-Acetylmuramoyl-L-alanine amidase
K0V03_20480	COG0464	growth
K0V03_20485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K0V03_20490	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K0V03_20495	COG0789	Transcriptional regulator
K0V03_20500	COG0174	glutamine synthetase
K0V03_20525	COG4282	regulation of fungal-type cell wall biogenesis
K0V03_20530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K0V03_20540	COG0135	phosphoribosylanthranilate isomerase activity
K0V03_20545	COG2211	Major facilitator Superfamily
K0V03_20550	COG3507	Belongs to the glycosyl hydrolase 43 family
K0V03_20555	COG1940	carbohydrate kinase activity
K0V03_20560	COG2115	Belongs to the xylose isomerase family
K0V03_20565	COG1070	Carbohydrate kinase
K0V03_20575	COG1525	nuclease
K0V03_20580	COG2814	Major facilitator Superfamily
K0V03_20585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K0V03_20600	COG0756	dUTP diphosphatase activity
K0V03_20640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K0V03_20655	COG3832	glyoxalase III activity
K0V03_20670	COG0697	spore germination
K0V03_20675	COG0531	amino acid
K0V03_20705	COG4195	phage-related replication protein
K0V03_20715	COG0346	lactoylglutathione lyase activity
K0V03_20720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K0V03_20725	COG1388	LysM domain
K0V03_20730	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K0V03_20735	COG4224	UPF0291 protein
K0V03_20740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K0V03_20750	COG3763	UPF0154 protein
K0V03_20760	COG0785	Cytochrome C biogenesis protein
K0V03_20765	COG2201	protein-glutamate methylesterase activity
K0V03_20770	COG4846	Membrane protein involved in cytochrome C biogenesis
K0V03_20780	COG0071	Belongs to the small heat shock protein (HSP20) family
K0V03_20795	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K0V03_20800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K0V03_20820	COG0824	Thioesterase
K0V03_20830	COG4841	protein insertion into membrane
K0V03_20835	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K0V03_20840	COG1832	CoA-binding protein
K0V03_20845	COG0187	DNA topoisomerase II activity
K0V03_20850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K0V03_20860	COG1115	amino acid carrier protein
K0V03_20865	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
K0V03_20875	COG5520	Belongs to the glycosyl hydrolase 30 family
K0V03_20880	COG3507	Belongs to the glycosyl hydrolase 43 family
K0V03_20885	COG2246	polysaccharide biosynthetic process
K0V03_20890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K0V03_20895	COG0586	Pfam SNARE associated Golgi protein
K0V03_20900	COG2404	hydrolase activity, acting on ester bonds
K0V03_20905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K0V03_20910	COG1024	Enoyl-CoA hydratase
K0V03_20915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K0V03_20920	COG0511	ligase activity, forming carbon-carbon bonds
K0V03_20925	COG0439	Biotin carboxylase
K0V03_20930	COG0318	PFAM AMP-dependent synthetase and ligase
K0V03_20935	COG1960	acyl-CoA dehydrogenase activity
K0V03_20950	COG1649	PFAM Uncharacterised BCR, COG1649
K0V03_20960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K0V03_20960	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
K0V03_20965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K0V03_20970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K0V03_20975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K0V03_20980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K0V03_20985	COG2027	D-alanyl-D-alanine carboxypeptidase
K0V03_20990	COG2017	converts alpha-aldose to the beta-anomer
K0V03_20995	COG0534	Mate efflux family protein
K0V03_21010	COG0582	viral genome integration into host DNA
K0V03_21015	COG0166	Belongs to the GPI family
K0V03_21020	COG0405	Gamma-glutamyltransferase
K0V03_21025	COG0583	DNA-binding transcription factor activity
K0V03_21030	COG0604	alcohol dehydrogenase
K0V03_21035	COG0493	'glutamate synthase
K0V03_21040	COG0070	glutamate synthase
K0V03_21040	COG0067	glutamate synthase
K0V03_21040	COG0069	glutamate synthase activity
K0V03_21045	COG0583	DNA-binding transcription factor activity
K0V03_21050	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K0V03_21055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K0V03_21065	COG0300	oxidoreductase activity
K0V03_21070	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
K0V03_21080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K0V03_21085	COG2814	Major facilitator Superfamily
K0V03_21090	COG1070	Carbohydrate kinase
K0V03_21095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K0V03_21100	COG0243	molybdopterin cofactor binding
K0V03_21130	COG0840	transmembrane signaling receptor activity
K0V03_21130	COG5278	phosphoserine phosphatase activity
K0V03_21135	COG2368	4-hydroxyphenylacetate
K0V03_21140	COG4305	rare lipoprotein A
K0V03_21145	COG3619	membrane
K0V03_21150	COG3866	Pectate lyase
K0V03_21155	COG2135	peptidase activity
K0V03_21165	COG2140	Oxalate decarboxylase
K0V03_21195	COG2720	vancomycin resistance protein
K0V03_21205	COG3655	Transcriptional regulator
K0V03_21210	COG3739	integral membrane protein
K0V03_21215	COG0583	DNA-binding transcription factor activity
K0V03_21220	COG0697	spore germination
K0V03_21230	COG0693	protein deglycase activity
K0V03_21235	COG2367	Beta-lactamase
K0V03_21255	COG0726	polysaccharide deacetylase
K0V03_21260	COG2314	TM2 domain
K0V03_21370	COG0457	Tetratricopeptide repeat
K0V03_21375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K0V03_21385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K0V03_21390	COG2226	methyltransferase
K0V03_21395	COG2211	Major facilitator Superfamily
K0V03_21400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K0V03_21425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K0V03_21445	COG5444	nuclease activity
K0V03_21450	COG4282	regulation of fungal-type cell wall biogenesis
K0V03_21455	COG1231	oxidoreductase activity
K0V03_21460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K0V03_21465	COG2207	Transcriptional regulator
K0V03_21465	COG0662	Cupin 2, conserved barrel domain protein
K0V03_21470	COG0456	acetyltransferase
K0V03_21475	COG1309	transcriptional regulator
K0V03_21480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K0V03_21485	COG3708	Transcriptional regulator
K0V03_21490	COG2378	regulation of single-species biofilm formation
K0V03_21500	COG0640	Transcriptional regulator
K0V03_21505	COG0741	lytic transglycosylase activity
K0V03_21510	COG2322	membrane
K0V03_21525	COG1619	proteins homologs of microcin C7 resistance protein MccF
K0V03_21530	COG3239	Fatty acid desaturase
K0V03_21535	COG4585	Histidine kinase
K0V03_21540	COG2197	response regulator
K0V03_21545	COG1388	LysM domain
K0V03_21545	COG3584	3D domain protein
K0V03_21550	COG0514	ATP-dependent DNA helicase (RecQ)
K0V03_21560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K0V03_21565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K0V03_21580	COG0071	Belongs to the small heat shock protein (HSP20) family
K0V03_21605	COG1012	belongs to the aldehyde dehydrogenase family
K0V03_21610	COG1657	PFAM Prenyltransferase squalene oxidase
K0V03_21615	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K0V03_21620	COG0733	neurotransmitter:sodium symporter activity
K0V03_21625	COG0385	Bile acid
K0V03_21630	COG0508	dehydrogenase complex catalyzes the overall conversion of
K0V03_21635	COG0567	Dehydrogenase, E1 component
K0V03_21640	COG4548	von Willebrand factor, type A
K0V03_21645	COG0714	Associated with various cellular activities
K0V03_21650	COG2032	superoxide dismutase activity
K0V03_21655	COG1388	LysM domain
K0V03_21655	COG0791	NLP P60 protein
K0V03_21660	COG1819	glycosyl
K0V03_21665	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K0V03_21670	COG0534	Mate efflux family protein
K0V03_21675	COG1366	Belongs to the anti-sigma-factor antagonist family
K0V03_21680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K0V03_21685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K0V03_21695	COG2962	Rard protein
K0V03_21710	COG2610	gluconate transmembrane transporter activity
K0V03_21715	COG1942	4-Oxalocrotonate Tautomerase
K0V03_21720	COG1733	regulation of RNA biosynthetic process
K0V03_21725	COG0778	Nitroreductase
K0V03_21730	COG0400	carboxylic ester hydrolase activity
K0V03_21745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K0V03_21750	COG0793	Belongs to the peptidase S41A family
K0V03_21750	COG3409	Peptidoglycan-binding domain 1 protein
K0V03_21755	COG2226	methyltransferase
K0V03_21765	COG1876	peptidase activity
K0V03_21770	COG0813	purine-nucleoside phosphorylase activity
K0V03_21785	COG0671	phosphoesterase, PA-phosphatase related
K0V03_21805	COG4479	Belongs to the UPF0346 family
K0V03_21815	COG1509	lysine 2,3-aminomutase activity
K0V03_21820	COG0456	acetyltransferase
K0V03_21825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K0V03_21830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K0V03_21835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K0V03_21840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K0V03_21855	COG0456	acetyltransferase
K0V03_21860	COG0463	Glycosyl transferase, family 2
K0V03_21875	COG4641	Protein conserved in bacteria
K0V03_21880	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
K0V03_21885	COG1086	Polysaccharide biosynthesis protein
K0V03_21890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K0V03_21895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K0V03_21900	COG1846	Transcriptional regulator
K0V03_21905	COG0534	Mate efflux family protein
K0V03_21915	COG4698	Protein conserved in bacteria
K0V03_21920	COG2755	lipolytic protein G-D-S-L family
K0V03_21925	COG1999	signal sequence binding
K0V03_21935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K0V03_21940	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K0V03_21945	COG1272	protein, Hemolysin III
K0V03_21950	COG0204	Acyl-transferase
K0V03_21955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K0V03_21960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K0V03_21970	COG2521	methyltransferase
K0V03_21970	COG2136	Putative SAM-dependent methyltransferase
K0V03_21980	COG0129	dihydroxy-acid dehydratase activity
K0V03_21985	COG1413	lyase activity
K0V03_21990	COG1418	mRNA catabolic process
K0V03_21995	COG0386	Belongs to the glutathione peroxidase family
K0V03_22000	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
K0V03_22005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K0V03_22015	COG1278	Cold shock
K0V03_22035	COG0328	RNA-DNA hybrid ribonuclease activity
K0V03_22040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
K0V03_22045	COG0328	RNA-DNA hybrid ribonuclease activity
K0V03_22055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K0V03_22070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K0V03_22080	COG1755	Isoprenylcysteine carboxyl methyltransferase
K0V03_22085	COG3424	synthase
K0V03_22090	COG2233	PERMEase
K0V03_22095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K0V03_22100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K0V03_22110	COG0800	Aldolase
K0V03_22115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K0V03_22120	COG1609	Transcriptional regulator
K0V03_22125	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
K0V03_22130	COG1028	Short-chain dehydrogenase reductase Sdr