locus-tag	class	description
AW03_000010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AW03_000020	COG0592	DNA-directed DNA polymerase activity
AW03_000040	COG2501	S4 domain
AW03_000050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AW03_000070	COG0187	DNA topoisomerase II activity
AW03_000080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW03_000110	COG0516	GMP reductase activity
AW03_000110	COG0517	IMP dehydrogenase activity
AW03_000120	COG1686	Belongs to the peptidase S11 family
AW03_000130	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AW03_000140	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AW03_000150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AW03_000160	COG1428	Deoxynucleoside kinase
AW03_000170	COG1428	Deoxynucleoside kinase
AW03_000180	COG1388	LysM domain
AW03_000180	COG3858	chitin binding
AW03_000190	COG1335	isochorismatase
AW03_000200	COG0590	tRNA wobble adenosine to inosine editing
AW03_000210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AW03_000220	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AW03_000230	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AW03_000270	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AW03_000280	COG3853	Toxic anion resistance protein (TelA)
AW03_000290	COG1982	Orn Lys Arg decarboxylase major
AW03_000300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AW03_000310	COG3870	Protein conserved in bacteria
AW03_000330	COG1728	Protein conserved in bacteria
AW03_000340	COG0470	DNA polymerase III
AW03_000350	COG1774	PSP1 C-terminal conserved region
AW03_000360	COG4467	Involved in initiation control of chromosome replication
AW03_000370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AW03_000380	COG2827	Endonuclease containing a URI domain
AW03_000390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AW03_000400	COG2002	toxin-antitoxin pair type II binding
AW03_000410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW03_000410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW03_000420	COG0084	hydrolase, TatD family'
AW03_000430	COG3584	3D domain protein
AW03_000430	COG3583	domain protein
AW03_000440	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW03_000450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AW03_000470	COG4466	Protein conserved in bacteria
AW03_000480	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AW03_000490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW03_000500	COG0251	oxidation-reduction process
AW03_000510	COG2088	sporulation resulting in formation of a cellular spore
AW03_000520	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AW03_000530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AW03_000540	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AW03_000550	COG0193	aminoacyl-tRNA hydrolase activity
AW03_000570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AW03_000580	COG2002	toxin-antitoxin pair type II binding
AW03_000590	COG2244	polysaccharide biosynthetic process
AW03_000600	COG3956	TIGRFAM MazG family protein
AW03_000610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AW03_000640	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AW03_000650	COG1098	S1 RNA binding domain
AW03_000660	COG2208	phosphoserine phosphatase activity
AW03_000670	COG2304	oxidoreductase activity
AW03_000680	COG0515	serine threonine protein kinase
AW03_000690	COG0037	tRNA processing
AW03_000710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AW03_000720	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AW03_000730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AW03_000740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW03_000750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW03_000760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW03_000770	COG0512	Glutamine amidotransferase of anthranilate synthase
AW03_000780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW03_000790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AW03_000800	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AW03_000810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AW03_000820	COG1396	sequence-specific DNA binding
AW03_000830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW03_000840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AW03_000850	COG4463	regulation of RNA biosynthetic process
AW03_000860	COG3880	PFAM UvrB UvrC protein
AW03_000870	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AW03_000880	COG0542	response to heat
AW03_000890	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AW03_000900	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AW03_000910	COG4956	integral membrane protein (PIN domain superfamily)
AW03_000920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AW03_000930	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AW03_000940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AW03_000950	COG1045	serine acetyltransferase
AW03_000960	COG0215	cysteine-tRNA ligase activity
AW03_000970	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AW03_000990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW03_001000	COG3688	RNA-binding protein containing a PIN domain
AW03_001010	COG1595	DNA-templated transcription, initiation
AW03_001020	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW03_001030	COG0250	Participates in transcription elongation, termination and antitermination
AW03_001040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AW03_001050	COG0081	regulation of translation
AW03_001060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AW03_001070	COG0222	ribosome binding
AW03_001080	COG2813	Specifically methylates the guanine in position
AW03_001090	COG0085	RNA polymerase activity
AW03_001100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AW03_001110	COG1358	cellular component organization or biogenesis
AW03_001120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AW03_001130	COG0049	tRNA binding
AW03_001140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AW03_001150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AW03_001160	COG0596	Alpha beta hydrolase
AW03_001170	COG0051	transcription antitermination factor activity, RNA binding
AW03_001180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AW03_001190	COG0088	Forms part of the polypeptide exit tunnel
AW03_001200	COG0089	rRNA binding
AW03_001210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AW03_001220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AW03_001230	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AW03_001240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AW03_001250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AW03_001260	COG0255	Belongs to the universal ribosomal protein uL29 family
AW03_001270	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AW03_001280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AW03_001300	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AW03_001320	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AW03_001330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AW03_001340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AW03_001360	COG1841	ribosomal large subunit assembly
AW03_001370	COG0200	Binds to the 23S rRNA
AW03_001380	COG0201	protein transport
AW03_001390	COG0563	adenylate kinase activity
AW03_001400	COG0024	Methionine aminopeptidase
AW03_001410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AW03_001420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AW03_001430	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AW03_001450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AW03_001460	COG0202	RNA polymerase activity
AW03_001470	COG0203	ribosomal protein L17
AW03_001480	COG1122	ATPase activity
AW03_001490	COG1122	ATPase activity
AW03_001500	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW03_001510	COG0101	tRNA pseudouridine synthase activity
AW03_001520	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AW03_001530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AW03_001540	COG2226	methyltransferase
AW03_001560	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_001570	COG0489	protein tyrosine kinase activity
AW03_001590	COG2194	sulfuric ester hydrolase activity
AW03_001600	COG0726	polysaccharide deacetylase
AW03_001610	COG0659	secondary active sulfate transmembrane transporter activity
AW03_001620	COG0385	Bile acid
AW03_001630	COG2819	hydrolase of the alpha beta superfamily
AW03_001640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_001650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_001660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_001670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_001670	COG2207	Transcriptional regulator
AW03_001680	COG3876	Protein conserved in bacteria
AW03_001690	COG1472	Belongs to the glycosyl hydrolase 3 family
AW03_001700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW03_001710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_001710	COG1263	PTS System
AW03_001720	COG1737	Transcriptional regulator
AW03_001730	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AW03_001740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_001750	COG1683	Conserved Protein
AW03_001770	COG1595	DNA-templated transcription, initiation
AW03_001780	COG5662	AntiSigma factor
AW03_001790	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW03_001800	COG4856	YbbR-like protein
AW03_001810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AW03_001820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AW03_001840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW03_001850	COG3002	Belongs to the UPF0753 family
AW03_001860	COG0288	reversible hydration of carbon dioxide
AW03_001880	COG5609	conserved protein (DUF2294)
AW03_001890	COG0640	Transcriptional regulator
AW03_001900	COG2814	Major facilitator Superfamily
AW03_001920	COG0596	Alpha beta hydrolase
AW03_001930	COG0745	RESPONSE REGULATOR receiver
AW03_001940	COG0642	Histidine kinase
AW03_001960	COG0515	serine threonine protein kinase
AW03_001990	COG1113	amino acid transport
AW03_002020	COG2602	Beta-lactamase
AW03_002030	COG2124	cytochrome p450
AW03_002050	COG0531	amino acid
AW03_002060	COG0584	glycerophosphoryl diester phosphodiesterase
AW03_002070	COG2271	Major facilitator Superfamily
AW03_002100	COG0456	acetyltransferase
AW03_002100	COG1846	Transcriptional regulator
AW03_002110	COG2271	Major facilitator Superfamily
AW03_002130	COG0697	spore germination
AW03_002140	COG2207	Transcriptional regulator
AW03_002140	COG1917	Cupin 2, conserved barrel domain protein
AW03_002150	COG1397	ADP-ribosylglycohydrolase
AW03_002160	COG5444	nuclease activity
AW03_002180	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AW03_002190	COG3591	Belongs to the peptidase S1B family
AW03_002210	COG0596	Alpha beta hydrolase
AW03_002220	COG1183	phosphatidylcholine synthase activity
AW03_002230	COG0586	Pfam SNARE associated Golgi protein
AW03_002240	COG0688	phosphatidylethanolamine metabolic process
AW03_002260	COG2312	Erythromycin esterase
AW03_002280	COG1301	dicarboxylic acid transport
AW03_002290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_002290	COG1263	PTS System
AW03_002290	COG2190	(PTS) system
AW03_002300	COG0363	glucosamine-6-phosphate deaminase activity
AW03_002330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW03_002340	COG0833	amino acid
AW03_002350	COG2040	homocysteine
AW03_002370	COG1115	amino acid carrier protein
AW03_002380	COG2066	Belongs to the glutaminase family
AW03_002390	COG4191	Histidine kinase
AW03_002400	COG0784	Response regulator, receiver
AW03_002410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW03_002420	COG1012	belongs to the aldehyde dehydrogenase family
AW03_002430	COG2271	Major facilitator Superfamily
AW03_002440	COG4948	Mandelate Racemase Muconate Lactonizing
AW03_002450	COG2186	Transcriptional regulator
AW03_002460	COG2721	sulfolactate sulfo-lyase activity
AW03_002470	COG3173	Aminoglycoside phosphotransferase
AW03_002490	COG0697	spore germination
AW03_002500	COG0745	RESPONSE REGULATOR receiver
AW03_002510	COG2205	protein histidine kinase activity
AW03_002520	COG1131	(ABC) transporter
AW03_002550	COG3773	Cell wall hydrolase
AW03_002560	COG2304	oxidoreductase activity
AW03_002570	COG3540	Alkaline phosphatase
AW03_002580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW03_002590	COG0805	protein transport
AW03_002600	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AW03_002610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW03_002620	COG0477	Major facilitator Superfamily
AW03_002630	COG1309	transcriptional regulator
AW03_002640	COG0252	asparaginase activity
AW03_002650	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AW03_002660	COG1714	RDD family
AW03_002670	COG3012	SEC-C Motif Domain Protein
AW03_002670	COG1405	negative regulation of cell septum assembly
AW03_002680	COG3290	protein histidine kinase activity
AW03_002690	COG3279	Response regulator of the LytR AlgR family
AW03_002700	COG4555	ABC transporter
AW03_002710	COG1668	transmembrane transport
AW03_002720	COG0667	Aldo Keto reductase
AW03_002740	COG1595	DNA-templated transcription, initiation
AW03_002750	COG1595	DNA-templated transcription, initiation
AW03_002760	COG1876	peptidase activity
AW03_002770	COG0457	Tetratricopeptide repeat
AW03_002780	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_002790	COG0366	Alpha amylase catalytic
AW03_002800	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW03_002810	COG1121	(ABC) transporter
AW03_002820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW03_002830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_002840	COG2310	stress, protein
AW03_002850	COG2310	stress, protein
AW03_002860	COG2310	stress, protein
AW03_002870	COG0861	Integral membrane protein TerC family
AW03_002890	COG3853	Toxic anion resistance protein (TelA)
AW03_002900	COG0477	Major facilitator Superfamily
AW03_002910	COG2814	Major facilitator Superfamily
AW03_002920	COG0640	Transcriptional regulator
AW03_002930	COG0517	IMP dehydrogenase activity
AW03_002930	COG4175	Glycine betaine
AW03_002940	COG4176	ABC-type proline glycine betaine transport system permease component
AW03_002950	COG2113	Glycine betaine
AW03_002960	COG1473	amidohydrolase
AW03_002970	COG1288	antiporter activity
AW03_002990	COG0366	Alpha amylase catalytic
AW03_003000	COG0039	L-malate dehydrogenase activity
AW03_003010	COG1620	l-lactate permease
AW03_003020	COG2814	Major facilitator Superfamily
AW03_003030	COG1846	Transcriptional regulator
AW03_003040	COG1280	lysine exporter protein (LysE YggA)
AW03_003050	COG3403	YqcI/YcgG family
AW03_003060	COG1113	amino acid transport
AW03_003070	COG3665	Urea carboxylase-associated protein
AW03_003080	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AW03_003090	COG1660	Displays ATPase and GTPase activities
AW03_003100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AW03_003110	COG2226	methyltransferase
AW03_003120	COG0583	DNA-binding transcription factor activity
AW03_003130	COG3458	cephalosporin-C deacetylase activity
AW03_003140	COG3541	Predicted nucleotidyltransferase
AW03_003150	COG0506	proline dehydrogenase activity
AW03_003160	COG1012	belongs to the aldehyde dehydrogenase family
AW03_003170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW03_003180	COG2508	Transcriptional regulator
AW03_003190	COG3689	TIGRFAM TIGR03943 family protein
AW03_003200	COG0701	Predicted permease
AW03_003210	COG2267	carboxylic ester hydrolase activity
AW03_003220	COG0492	ferredoxin-NADP+ reductase activity
AW03_003230	COG1587	Uroporphyrinogen-III synthase
AW03_003230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW03_003240	COG2146	nitrite reductase [NAD(P)H] activity
AW03_003250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW03_003260	COG0243	molybdopterin cofactor binding
AW03_003270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW03_003280	COG2223	nitrite transmembrane transporter activity
AW03_003290	COG1469	GTP cyclohydrolase I activity
AW03_003300	COG1376	ErfK ybiS ycfS ynhG family protein
AW03_003310	COG0523	cobalamin synthesis protein
AW03_003320	COG0765	amino acid transport
AW03_003330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_003350	COG1714	RDD family
AW03_003370	COG2723	6-phospho-beta-galactosidase activity
AW03_003390	COG3209	COG3209 Rhs family protein
AW03_003400	COG3290	protein histidine kinase activity
AW03_003400	COG0840	transmembrane signaling receptor activity
AW03_003410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AW03_003420	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AW03_003430	COG1733	regulation of RNA biosynthetic process
AW03_003440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_003460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_003470	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AW03_003480	COG2814	Major facilitator Superfamily
AW03_003500	COG0697	spore germination
AW03_003510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_003530	COG2364	Membrane
AW03_003540	COG1126	abc transporter atp-binding protein
AW03_003550	COG0765	amino acid transport
AW03_003560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_003570	COG0583	DNA-binding transcription factor activity
AW03_003580	COG0163	prenyltransferase activity
AW03_003590	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AW03_003620	COG0596	Alpha beta hydrolase
AW03_003630	COG3104	oligopeptide transport
AW03_003640	COG5434	Belongs to the glycosyl hydrolase 28 family
AW03_003660	COG0697	spore germination
AW03_003680	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AW03_003690	COG1136	(ABC) transporter
AW03_003700	COG0577	efflux transmembrane transporter activity
AW03_003710	COG0745	RESPONSE REGULATOR receiver
AW03_003720	COG5002	protein histidine kinase activity
AW03_003720	COG3850	Histidine kinase
AW03_003730	COG0457	Tetratricopeptide repeat
AW03_003760	COG0527	aspartate kinase activity
AW03_003770	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_003780	COG4605	iron ion homeostasis
AW03_003790	COG4604	ABC transporter, ATP-binding protein
AW03_003800	COG4607	ABC-type enterochelin transport system periplasmic component
AW03_003810	COG2814	Major facilitator Superfamily
AW03_003820	COG1309	transcriptional regulator
AW03_003830	COG0778	Nitroreductase
AW03_003840	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AW03_003850	COG0640	Transcriptional regulator
AW03_003860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_003870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW03_003880	COG1012	belongs to the aldehyde dehydrogenase family
AW03_003890	COG4975	Glucose uptake
AW03_003900	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_003910	COG4549	nuclear export factor GLE1
AW03_003920	COG1276	copper resistance
AW03_003920	COG2372	response to copper ion
AW03_003930	COG1349	DNA-binding transcription factor activity
AW03_003950	COG2213	PTS system mannitol-specific
AW03_003960	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_003970	COG0246	Mannitol dehydrogenase
AW03_003980	COG0473	3-isopropylmalate dehydrogenase activity
AW03_004000	COG0681	Belongs to the peptidase S26 family
AW03_004010	COG0412	Dienelactone hydrolase
AW03_004020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW03_004040	COG0561	phosphatase activity
AW03_004050	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AW03_004060	COG1914	H( )-stimulated, divalent metal cation uptake system
AW03_004070	COG4336	lyase activity
AW03_004080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AW03_004090	COG1984	allophanate hydrolase subunit 2
AW03_004100	COG1414	Transcriptional regulator
AW03_004110	COG2755	lipolytic protein G-D-S-L family
AW03_004130	COG2329	Antibiotic biosynthesis monooxygenase
AW03_004140	COG0768	penicillin binding
AW03_004150	COG4989	oxidoreductase activity
AW03_004160	COG3711	transcriptional antiterminator
AW03_004170	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_004180	COG2226	methyltransferase
AW03_004190	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_004200	COG1917	Cupin 2, conserved barrel domain protein
AW03_004210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_004220	COG3871	stress protein (general stress protein 26)
AW03_004240	COG2814	Major facilitator Superfamily
AW03_004250	COG1522	sequence-specific DNA binding
AW03_004260	COG0551	DNA topoisomerase type I activity
AW03_004260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW03_004270	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AW03_004280	COG3706	GGDEF domain
AW03_004290	COG5298	Protein conserved in bacteria
AW03_004300	COG1215	transferase activity, transferring glycosyl groups
AW03_004320	COG0531	amino acid
AW03_004330	COG0494	nUDIX hydrolase
AW03_004340	COG0028	Belongs to the TPP enzyme family
AW03_004360	COG1914	H( )-stimulated, divalent metal cation uptake system
AW03_004370	COG2261	transglycosylase associated protein
AW03_004380	COG4876	unkown
AW03_004390	COG2217	Heavy metal translocating P-type atpase
AW03_004400	COG3729	General stress protein
AW03_004410	COG0662	Cupin 2, conserved barrel domain protein
AW03_004420	COG2329	Antibiotic biosynthesis monooxygenase
AW03_004430	COG3546	catalase activity
AW03_004440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AW03_004450	COG3290	protein histidine kinase activity
AW03_004460	COG4565	transcriptional regulatory protein
AW03_004470	COG1301	dicarboxylic acid transport
AW03_004480	COG0628	permease
AW03_004490	COG1131	(ABC) transporter
AW03_004500	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW03_004520	COG1960	acyl-CoA dehydrogenase activity
AW03_004550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW03_004560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_004570	COG1181	Belongs to the D-alanine--D-alanine ligase family
AW03_004580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW03_004590	COG0513	Belongs to the DEAD box helicase family
AW03_004600	COG3402	PFAM membrane-flanked domain
AW03_004610	COG3428	Bacterial PH domain
AW03_004620	COG0705	Rhomboid family
AW03_004630	COG0736	holo-[acyl-carrier-protein] synthase activity
AW03_004640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AW03_004650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW03_004660	COG0864	Transcriptional regulator
AW03_004670	COG2337	Toxic component of a toxin-antitoxin (TA) module
AW03_004690	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_004700	COG2172	sigma factor antagonist activity
AW03_004710	COG2208	phosphoserine phosphatase activity
AW03_004720	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_004730	COG2172	sigma factor antagonist activity
AW03_004740	COG1191	sigma factor activity
AW03_004750	COG2208	phosphoserine phosphatase activity
AW03_004770	COG1673	EVE domain
AW03_004780	COG1846	Transcriptional regulator
AW03_004790	COG2183	response to ionizing radiation
AW03_004800	COG3091	SprT-like family
AW03_004840	COG0515	serine threonine protein kinase
AW03_004900	COG0515	serine threonine protein kinase
AW03_004910	COG1132	(ABC) transporter
AW03_004940	COG1476	TRANSCRIPTIONal
AW03_004960	COG3239	Fatty acid desaturase
AW03_004970	COG1278	Cold shock
AW03_004980	COG1329	Transcriptional regulator
AW03_004990	COG2207	Transcriptional regulator
AW03_004990	COG1917	Cupin 2, conserved barrel domain protein
AW03_005000	COG0697	spore germination
AW03_005010	COG2207	Transcriptional regulator
AW03_005010	COG3708	Transcriptional regulator
AW03_005020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_005030	COG0477	Major facilitator Superfamily
AW03_005050	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AW03_005070	COG0697	spore germination
AW03_005080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_005090	COG2030	dehydratase
AW03_005100	COG3545	Serine hydrolase
AW03_005110	COG1733	regulation of RNA biosynthetic process
AW03_005120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_005130	COG1733	regulation of RNA biosynthetic process
AW03_005140	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW03_005160	COG2814	Major facilitator Superfamily
AW03_005170	COG1309	transcriptional regulator
AW03_005190	COG0640	Transcriptional regulator
AW03_005200	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW03_005210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_005230	COG0726	polysaccharide deacetylase
AW03_005250	COG5002	protein histidine kinase activity
AW03_005260	COG0745	RESPONSE REGULATOR receiver
AW03_005270	COG0697	spore germination
AW03_005280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_005290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AW03_005300	COG0640	Transcriptional regulator
AW03_005310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW03_005330	COG4585	Histidine kinase
AW03_005340	COG2197	response regulator
AW03_005350	COG2409	Drug exporters of the RND superfamily
AW03_005360	COG0596	Alpha beta hydrolase
AW03_005370	COG1811	Na channel or pump
AW03_005380	COG4978	Transcriptional regulator
AW03_005380	COG0789	Transcriptional regulator
AW03_005390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW03_005400	COG0778	Nitroreductase
AW03_005410	COG0346	lactoylglutathione lyase activity
AW03_005420	COG2259	Doxx family
AW03_005430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_005470	COG2323	membrane
AW03_005480	COG2323	membrane
AW03_005490	COG0071	Belongs to the small heat shock protein (HSP20) family
AW03_005520	COG1309	transcriptional regulator
AW03_005540	COG0456	acetyltransferase
AW03_005560	COG2814	Major facilitator Superfamily
AW03_005590	COG1113	amino acid transport
AW03_005600	COG2318	DinB family
AW03_005610	COG1846	Transcriptional regulator
AW03_005620	COG2409	Drug exporters of the RND superfamily
AW03_005620	COG1033	growth of symbiont in host cell
AW03_005630	COG0778	Nitroreductase
AW03_005640	COG1846	Transcriptional regulator
AW03_005650	COG2814	Major facilitator Superfamily
AW03_005660	COG0730	response to heat
AW03_005670	COG1802	Transcriptional regulator
AW03_005680	COG1388	LysM domain
AW03_005680	COG3858	chitin binding
AW03_005690	COG1819	glycosyl
AW03_005710	COG1785	Belongs to the alkaline phosphatase family
AW03_005720	COG5646	InterPro IPR014922
AW03_005740	COG0454	-acetyltransferase
AW03_005750	COG1078	dGTPase activity
AW03_005760	COG1388	LysM domain
AW03_005770	COG2814	Major facilitator Superfamily
AW03_005780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW03_005790	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW03_005800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW03_005810	COG2723	6-phospho-beta-galactosidase activity
AW03_005820	COG2188	Transcriptional regulator
AW03_005830	COG1940	carbohydrate kinase activity
AW03_005840	COG1482	cell wall glycoprotein biosynthetic process
AW03_005850	COG4124	Belongs to the glycosyl hydrolase 26 family
AW03_005870	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AW03_005880	COG0802	atpase or kinase
AW03_005890	COG1214	PFAM Peptidase M22, glycoprotease
AW03_005900	COG0456	acetyltransferase
AW03_005910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AW03_005920	COG0488	(ABC) transporter
AW03_005930	COG0315	cyclic pyranopterin monophosphate synthase activity
AW03_005940	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AW03_005950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW03_005960	COG0805	protein transport
AW03_005980	COG1266	CAAX protease self-immunity
AW03_005990	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AW03_006000	COG0459	protein refolding
AW03_006010	COG1073	alpha beta
AW03_006020	COG0457	Tetratricopeptide repeat
AW03_006030	COG1063	alcohol dehydrogenase
AW03_006040	COG2211	Major facilitator Superfamily
AW03_006050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW03_006060	COG1842	Phage shock protein A
AW03_006070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW03_006080	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AW03_006090	COG4260	virion core protein, lumpy skin disease virus
AW03_006110	COG2814	Major facilitator Superfamily
AW03_006120	COG1063	alcohol dehydrogenase
AW03_006130	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AW03_006140	COG0823	Involved in the tonB-independent uptake of proteins
AW03_006180	COG2267	carboxylic ester hydrolase activity
AW03_006200	COG2132	Multicopper oxidase
AW03_006220	COG1113	amino acid transport
AW03_006230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW03_006240	COG0714	Associated with various cellular activities
AW03_006250	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AW03_006260	COG1305	Transglutaminase-like
AW03_006270	COG0519	Catalyzes the synthesis of GMP from XMP
AW03_006270	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AW03_006300	COG2252	PERMEase
AW03_006310	COG3064	Membrane
AW03_006330	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AW03_006350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AW03_006360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AW03_006370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AW03_006380	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AW03_006400	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AW03_006410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AW03_006420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AW03_006430	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AW03_006440	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AW03_006450	COG0138	bifunctional purine biosynthesis protein purh
AW03_006460	COG0151	Belongs to the GarS family
AW03_006470	COG1522	sequence-specific DNA binding
AW03_006480	COG0531	amino acid
AW03_006500	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AW03_006510	COG1470	cell adhesion involved in biofilm formation
AW03_006520	COG4496	protein, YerC YecD
AW03_006530	COG0069	glutamate synthase activity
AW03_006550	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AW03_006560	COG0210	DNA helicase
AW03_006570	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AW03_006580	COG4851	CamS sex pheromone cAM373 precursor
AW03_006590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW03_006600	COG1285	pathogenesis
AW03_006610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW03_006620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AW03_006630	COG0154	amidase activity
AW03_006640	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AW03_006650	COG1309	transcriptional regulator
AW03_006660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW03_006670	COG1597	lipid kinase activity
AW03_006680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW03_006690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AW03_006710	COG5293	efflux transmembrane transporter activity
AW03_006790	COG5444	nuclease activity
AW03_006810	COG3586	endonuclease activity
AW03_006830	COG0457	Tetratricopeptide repeat
AW03_006850	COG0217	transcriptional regulatory protein
AW03_006870	COG1309	transcriptional regulator
AW03_006880	COG3631	Ketosteroid isomerase-related protein
AW03_006890	COG0702	epimerase
AW03_006920	COG3546	catalase activity
AW03_006930	COG0454	-acetyltransferase
AW03_006950	COG5578	integral membrane protein
AW03_006960	COG2972	Histidine kinase
AW03_006970	COG2207	Transcriptional regulator
AW03_006970	COG4753	response regulator
AW03_006980	COG1653	transport
AW03_006990	COG1175	transmembrane transport
AW03_007000	COG0395	ABC-type sugar transport system, permease component
AW03_007010	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AW03_007020	COG2207	Transcriptional regulator
AW03_007030	COG2755	lipolytic protein G-D-S-L family
AW03_007050	COG5578	integral membrane protein
AW03_007060	COG3401	FG-GAP repeat protein
AW03_007070	COG3401	FG-GAP repeat protein
AW03_007080	COG2755	lipolytic protein G-D-S-L family
AW03_007090	COG1874	Beta-galactosidase
AW03_007110	COG1653	transport
AW03_007120	COG4209	transmembrane transport
AW03_007130	COG0395	ABC-type sugar transport system, permease component
AW03_007140	COG1486	melibiose metabolic process
AW03_007150	COG2323	membrane
AW03_007160	COG2329	Antibiotic biosynthesis monooxygenase
AW03_007170	COG0346	lactoylglutathione lyase activity
AW03_007200	COG5583	Uncharacterized small protein (DUF2292)
AW03_007210	COG0670	Belongs to the BI1 family
AW03_007220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW03_007240	COG2124	cytochrome p450
AW03_007240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AW03_007250	COG1368	sulfuric ester hydrolase activity
AW03_007260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AW03_007270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW03_007280	COG1442	glycosyl transferase family 8
AW03_007290	COG1216	Glycosyl transferase, family 2
AW03_007300	COG1442	glycosyl transferase family 8
AW03_007310	COG2223	nitrite transmembrane transporter activity
AW03_007320	COG1011	Hydrolase
AW03_007330	COG0531	amino acid
AW03_007340	COG1012	belongs to the aldehyde dehydrogenase family
AW03_007350	COG0840	transmembrane signaling receptor activity
AW03_007360	COG0488	(ABC) transporter
AW03_007390	COG0789	Transcriptional regulator
AW03_007400	COG2814	Major facilitator Superfamily
AW03_007430	COG0488	(ABC) transporter
AW03_007440	COG0513	Belongs to the DEAD box helicase family
AW03_007450	COG0456	acetyltransferase
AW03_007460	COG2130	NADP-dependent
AW03_007470	COG1120	ATPase activity
AW03_007480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_007490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_007500	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AW03_007530	COG3866	Pectate lyase
AW03_007540	COG0471	metal ion transport
AW03_007550	COG3290	protein histidine kinase activity
AW03_007560	COG4565	transcriptional regulatory protein
AW03_007570	COG3181	Tripartite tricarboxylate transporter family receptor
AW03_007580	COG2851	Citrate transporter
AW03_007590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_007600	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AW03_007610	COG1254	Belongs to the acylphosphatase family
AW03_007620	COG2258	MOSC domain
AW03_007660	COG0024	Methionine aminopeptidase
AW03_007670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_007670	COG1263	PTS System
AW03_007680	COG1368	sulfuric ester hydrolase activity
AW03_007700	COG1115	amino acid carrier protein
AW03_007710	COG0531	amino acid
AW03_007750	COG0697	spore germination
AW03_007760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_007760	COG1263	PTS System
AW03_007770	COG0366	Alpha amylase catalytic
AW03_007780	COG2188	Transcriptional regulator
AW03_007790	COG0778	Nitroreductase
AW03_007800	COG0737	Belongs to the 5'-nucleotidase family
AW03_007810	COG0693	protein deglycase activity
AW03_007820	COG2814	Major facilitator Superfamily
AW03_007830	COG4840	Belongs to the UPF0435 family
AW03_007840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW03_007850	COG4980	gas vesicle protein
AW03_007860	COG1295	ribonuclease BN
AW03_007880	COG0477	Major facilitator Superfamily
AW03_007890	COG0387	Pfam Sodium calcium exchanger
AW03_007910	COG0668	transmembrane transport
AW03_007920	COG0535	radical SAM domain protein
AW03_007940	COG0726	polysaccharide deacetylase
AW03_007950	COG2084	Dehydrogenase
AW03_007960	COG0598	Magnesium transport protein CorA
AW03_007970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW03_007980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW03_008000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW03_008010	COG4637	Psort location Cytoplasmic, score
AW03_008030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW03_008040	COG0022	dehydrogenase e1 component
AW03_008050	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW03_008060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW03_008070	COG3284	Transcriptional regulator
AW03_008090	COG1742	UPF0060 membrane protein
AW03_008130	COG4842	Belongs to the WXG100 family
AW03_008140	COG1486	melibiose metabolic process
AW03_008150	COG1737	Transcriptional regulator
AW03_008160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_008160	COG1263	PTS System
AW03_008170	COG1132	(ABC) transporter
AW03_008180	COG1132	(ABC) transporter
AW03_008190	COG2259	Doxx family
AW03_008200	COG2514	catechol 2,3-dioxygenase activity
AW03_008210	COG4585	Histidine kinase
AW03_008220	COG2197	response regulator
AW03_008230	COG1131	(ABC) transporter
AW03_008240	COG1511	domain protein
AW03_008240	COG0842	Transport permease protein
AW03_008250	COG0842	Transport permease protein
AW03_008270	COG1695	Transcriptional regulator
AW03_008280	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AW03_008320	COG1131	(ABC) transporter
AW03_008330	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AW03_008340	COG1309	transcriptional regulator
AW03_008350	COG2814	Major facilitator Superfamily
AW03_008360	COG2318	DinB family
AW03_008370	COG2814	Major facilitator Superfamily
AW03_008380	COG1846	Transcriptional regulator
AW03_008390	COG0392	lysyltransferase activity
AW03_008390	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AW03_008400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_008410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_008420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_008430	COG0384	phenazine biosynthesis protein PhzF
AW03_008440	COG0778	Nitroreductase
AW03_008470	COG1090	epimerase
AW03_008480	COG2137	regulation of response to DNA damage stimulus
AW03_008510	COG2814	Major facilitator Superfamily
AW03_008540	COG3103	Sh3 type 3 domain protein
AW03_008550	COG5658	integral membrane protein
AW03_008560	COG0596	Alpha beta hydrolase
AW03_008570	COG0463	Glycosyl transferase, family 2
AW03_008580	COG4485	Bacterial membrane protein, YfhO
AW03_008590	COG1988	membrane-bound metal-dependent
AW03_008600	COG1194	a g-specific adenine glycosylase
AW03_008620	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_008650	COG3557	Belongs to the UPF0374 family
AW03_008660	COG1132	(ABC) transporter
AW03_008670	COG4129	membrane
AW03_008680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AW03_008690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AW03_008700	COG0735	belongs to the Fur family
AW03_008730	COG4326	sporulation control protein
AW03_008750	COG3340	Belongs to the peptidase S51 family
AW03_008770	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AW03_008790	COG0753	catalase activity
AW03_008800	COG1116	anion transmembrane transporter activity
AW03_008810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW03_008820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW03_008830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_008850	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AW03_008870	COG1476	TRANSCRIPTIONal
AW03_008880	COG3382	B3 4 domain protein
AW03_008890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AW03_008910	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AW03_008920	COG0789	Transcriptional regulator
AW03_008930	COG1664	Polymer-forming cytoskeletal
AW03_008940	COG1664	Polymer-forming cytoskeletal
AW03_008950	COG2766	serine protein kinase
AW03_008960	COG2718	Belongs to the UPF0229 family
AW03_008970	COG1846	Transcriptional regulator
AW03_008980	COG1566	PFAM secretion protein HlyD family protein
AW03_008990	COG2814	Major facilitator Superfamily
AW03_009000	COG0655	NAD(P)H dehydrogenase (quinone) activity
AW03_009030	COG1725	Transcriptional regulator
AW03_009040	COG1131	(ABC) transporter
AW03_009050	COG1131	(ABC) transporter
AW03_009060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW03_009070	COG1278	Cold shock
AW03_009080	COG1464	Belongs to the NlpA lipoprotein family
AW03_009090	COG3706	GGDEF domain
AW03_009100	COG1823	symporter activity
AW03_009140	COG5577	PFAM Coat F domain
AW03_009150	COG4085	toxin activity
AW03_009150	COG1525	nuclease
AW03_009150	COG0737	Belongs to the 5'-nucleotidase family
AW03_009160	COG3764	Sortase (surface protein transpeptidase)
AW03_009170	COG0564	pseudouridine synthase activity
AW03_009190	COG0517	IMP dehydrogenase activity
AW03_009200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW03_009210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW03_009210	COG3153	acetyltransferase
AW03_009220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW03_009230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW03_009240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AW03_009250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AW03_009260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW03_009270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AW03_009280	COG2203	Gaf domain
AW03_009280	COG4585	Histidine kinase
AW03_009290	COG2197	response regulator
AW03_009300	COG0431	NADPH-dependent FMN reductase
AW03_009330	COG1388	LysM domain
AW03_009330	COG0791	NLP P60 protein
AW03_009340	COG1959	2 iron, 2 sulfur cluster binding
AW03_009360	COG0668	transmembrane transport
AW03_009370	COG2719	SpoVR family
AW03_009380	COG1785	Belongs to the alkaline phosphatase family
AW03_009390	COG1388	LysM domain
AW03_009390	COG0791	NLP P60 protein
AW03_009400	COG0583	DNA-binding transcription factor activity
AW03_009410	COG0372	Belongs to the citrate synthase family
AW03_009420	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_009430	COG0531	amino acid
AW03_009440	COG0733	neurotransmitter:sodium symporter activity
AW03_009460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_009470	COG0456	acetyltransferase
AW03_009500	COG1595	DNA-templated transcription, initiation
AW03_009510	COG0667	Aldo Keto reductase
AW03_009520	COG0204	Acyl-transferase
AW03_009530	COG1253	flavin adenine dinucleotide binding
AW03_009540	COG0789	Transcriptional regulator
AW03_009550	COG0436	Aminotransferase
AW03_009560	COG1253	flavin adenine dinucleotide binding
AW03_009570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW03_009580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW03_009590	COG0584	glycerophosphoryl diester phosphodiesterase
AW03_009610	COG0668	transmembrane transport
AW03_009620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AW03_009630	COG0726	polysaccharide deacetylase
AW03_009640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW03_009650	COG1757	Na H antiporter
AW03_009660	COG0589	response to stress
AW03_009680	COG1132	(ABC) transporter
AW03_009690	COG1132	(ABC) transporter
AW03_009700	COG0702	epimerase
AW03_009740	COG0189	ligase activity
AW03_009750	COG0189	ligase activity
AW03_009760	COG4399	Belongs to the UPF0754 family
AW03_009770	COG3679	Belongs to the UPF0342 family
AW03_009780	COG4335	DNA alkylation repair
AW03_009790	COG0561	phosphatase activity
AW03_009800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW03_009810	COG0475	glutathione-regulated potassium exporter activity
AW03_009820	COG0490	domain, Protein
AW03_009840	COG1024	Enoyl-CoA hydratase
AW03_009860	COG4152	abc transporter atp-binding protein
AW03_009870	COG1668	transmembrane transport
AW03_009880	COG0420	3'-5' exonuclease activity
AW03_009890	COG4717	serine-type aminopeptidase activity
AW03_009900	COG3481	metal-dependent phosphohydrolase, HD sub domain
AW03_009920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW03_009950	COG1846	Transcriptional regulator
AW03_009960	COG4980	gas vesicle protein
AW03_009990	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AW03_010000	COG0537	adenosine 5'-monophosphoramidase activity
AW03_010010	COG1131	(ABC) transporter
AW03_010020	COG4473	ABC transporter
AW03_010040	COG1473	amidohydrolase
AW03_010050	COG3069	C4-dicarboxylate transmembrane transporter activity
AW03_010070	COG2329	Antibiotic biosynthesis monooxygenase
AW03_010080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW03_010090	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AW03_010120	COG1309	transcriptional regulator
AW03_010130	COG1511	domain protein
AW03_010140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW03_010150	COG4377	Putative membrane peptidase family (DUF2324)
AW03_010160	COG1363	Peptidase, m42
AW03_010170	COG4405	Protein conserved in bacteria
AW03_010180	COG1301	dicarboxylic acid transport
AW03_010190	COG1234	tRNA 3'-trailer cleavage
AW03_010200	COG0095	Lipoate-protein ligase
AW03_010220	COG0702	epimerase
AW03_010230	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_010250	COG0501	Belongs to the peptidase M48B family
AW03_010260	COG1404	Belongs to the peptidase S8 family
AW03_010270	COG0456	acetyltransferase
AW03_010280	COG0604	alcohol dehydrogenase
AW03_010290	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AW03_010300	COG0406	alpha-ribazole phosphatase activity
AW03_010310	COG0183	Belongs to the thiolase family
AW03_010330	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_010340	COG1268	BioY protein
AW03_010350	COG0840	transmembrane signaling receptor activity
AW03_010360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW03_010360	COG0723	plastoquinol--plastocyanin reductase activity
AW03_010370	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_010390	COG4903	ComK protein
AW03_010400	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_010420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW03_010450	COG0398	Pfam SNARE associated Golgi protein
AW03_010460	COG0681	Belongs to the peptidase S26 family
AW03_010470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW03_010480	COG1846	Transcriptional regulator
AW03_010490	COG0738	Major facilitator superfamily
AW03_010500	COG0673	inositol 2-dehydrogenase activity
AW03_010510	COG0561	phosphatase activity
AW03_010520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW03_010530	COG1609	Transcriptional regulator
AW03_010540	COG3180	Ammonia monooxygenase
AW03_010550	COG0477	Major facilitator Superfamily
AW03_010550	COG2814	Major facilitator Superfamily
AW03_010560	COG4533	DNA binding
AW03_010570	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AW03_010580	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AW03_010590	COG1074	ATP-dependent DNA helicase activity
AW03_010600	COG0420	3'-5' exonuclease activity
AW03_010610	COG0419	ATPase involved in DNA repair
AW03_010620	COG1403	HNH endonuclease
AW03_010700	COG5337	Spore coat protein CotH
AW03_010710	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW03_010730	COG1404	Belongs to the peptidase S8 family
AW03_010750	COG0367	asparagine synthase
AW03_010760	COG1562	ergosterol biosynthetic process
AW03_010770	COG0534	Mate efflux family protein
AW03_010780	COG1917	Cupin 2, conserved barrel domain protein
AW03_010780	COG2207	Transcriptional regulator
AW03_010790	COG1609	Transcriptional regulator
AW03_010800	COG0673	inositol 2-dehydrogenase activity
AW03_010810	COG2318	DinB family
AW03_010820	COG1279	arginine transmembrane transporter activity
AW03_010830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_010840	COG1357	PFAM Pentapeptide repeats (8 copies)
AW03_010850	COG2267	carboxylic ester hydrolase activity
AW03_010860	COG0529	Catalyzes the synthesis of activated sulfate
AW03_010870	COG2046	Belongs to the sulfate adenylyltransferase family
AW03_010880	COG0175	sulfate reduction
AW03_010890	COG2045	Belongs to the ComB family
AW03_010900	COG1809	phosphosulfolactate synthase activity
AW03_010910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_010920	COG4948	Mandelate Racemase Muconate Lactonizing
AW03_010930	COG2814	Major facilitator Superfamily
AW03_010940	COG0454	-acetyltransferase
AW03_010950	COG2153	protein acetylation
AW03_010960	COG0646	methionine synthase
AW03_010960	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AW03_010970	COG1666	GTP binding
AW03_010980	COG2996	Protein conserved in bacteria
AW03_011020	COG1695	Transcriptional regulator
AW03_011050	COG3227	Zinc metalloprotease (Elastase)
AW03_011060	COG1307	EDD domain protein, DegV family
AW03_011070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_011120	COG0561	phosphatase activity
AW03_011130	COG1073	alpha beta
AW03_011140	COG2151	metal-sulfur cluster biosynthetic enzyme
AW03_011160	COG0277	FAD linked oxidase domain protein
AW03_011170	COG2271	Major facilitator Superfamily
AW03_011180	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AW03_011210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW03_011220	COG0505	Belongs to the CarA family
AW03_011230	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AW03_011240	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AW03_011270	COG2267	carboxylic ester hydrolase activity
AW03_011290	COG1744	ABC transporter substrate-binding protein PnrA-like
AW03_011320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW03_011330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW03_011340	COG5504	Zn-dependent protease
AW03_011350	COG0444	Belongs to the ABC transporter superfamily
AW03_011360	COG4608	Belongs to the ABC transporter superfamily
AW03_011380	COG0601	transmembrane transport
AW03_011390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW03_011410	COG0180	Tryptophanyl-tRNA synthetase
AW03_011420	COG4166	transmembrane transport
AW03_011430	COG0601	transmembrane transport
AW03_011440	COG0444	Belongs to the ABC transporter superfamily
AW03_011450	COG4608	Belongs to the ABC transporter superfamily
AW03_011460	COG2814	Major facilitator Superfamily
AW03_011470	COG0456	acetyltransferase
AW03_011480	COG1393	Belongs to the ArsC family
AW03_011490	COG0861	Integral membrane protein TerC family
AW03_011500	COG4862	establishment of competence for transformation
AW03_011510	COG4469	Competence protein
AW03_011520	COG1164	Oligoendopeptidase f
AW03_011550	COG2346	COG2346, Truncated hemoglobins
AW03_011560	COG0741	lytic transglycosylase activity
AW03_011570	COG4116	CYTH
AW03_011590	COG2357	RelA SpoT domain protein
AW03_011600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AW03_011610	COG0564	pseudouridine synthase activity
AW03_011620	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AW03_011630	COG0475	glutathione-regulated potassium exporter activity
AW03_011630	COG0569	domain protein
AW03_011640	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW03_011650	COG0352	thiamine-phosphate diphosphorylase activity
AW03_011660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW03_011670	COG2104	thiamine diphosphate biosynthetic process
AW03_011680	COG2022	thiamine diphosphate biosynthetic process
AW03_011690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW03_011700	COG0351	phosphomethylpyrimidine kinase
AW03_011710	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AW03_011820	COG0210	DNA helicase
AW03_011840	COG2153	protein acetylation
AW03_011850	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AW03_011860	COG2382	esterase
AW03_011870	COG0626	cystathionine gamma-synthase activity
AW03_011880	COG0626	cystathionine gamma-synthase activity
AW03_011890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_011900	COG5505	Protein of unknown function (DUF819)
AW03_011980	COG0457	Tetratricopeptide repeat
AW03_011990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AW03_012010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_012010	COG3711	transcriptional antiterminator
AW03_012020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW03_012020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_012020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW03_012030	COG1482	cell wall glycoprotein biosynthetic process
AW03_012050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_012070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AW03_012100	COG0109	protoheme IX farnesyltransferase activity
AW03_012120	COG0726	polysaccharide deacetylase
AW03_012150	COG5504	Zn-dependent protease
AW03_012160	COG2205	protein histidine kinase activity
AW03_012180	COG3383	formate dehydrogenase (NAD+) activity
AW03_012190	COG2427	Protein of unknown function (DUF1641)
AW03_012210	COG1051	belongs to the nudix hydrolase family
AW03_012220	COG2124	cytochrome p450
AW03_012230	COG1819	glycosyl
AW03_012250	COG1587	Uroporphyrinogen-III synthase
AW03_012260	COG0390	transport system, permease component
AW03_012270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AW03_012280	COG0697	spore germination
AW03_012290	COG4297	protein containing double-stranded beta helix domain
AW03_012310	COG1252	NADH dehydrogenase
AW03_012320	COG1904	glucuronate isomerase
AW03_012330	COG2211	Major facilitator Superfamily
AW03_012340	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AW03_012350	COG1063	alcohol dehydrogenase
AW03_012360	COG1312	Catalyzes the dehydration of D-mannonate
AW03_012370	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_012380	COG2271	Major facilitator Superfamily
AW03_012390	COG1609	Transcriptional regulator
AW03_012400	COG0246	Mannitol dehydrogenase
AW03_012410	COG2721	sulfolactate sulfo-lyase activity
AW03_012420	COG0730	response to heat
AW03_012430	COG2318	DinB family
AW03_012440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AW03_012450	COG0457	Tetratricopeptide repeat
AW03_012470	COG2350	Protein conserved in bacteria
AW03_012480	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW03_012480	COG3409	Peptidoglycan-binding domain 1 protein
AW03_012480	COG1388	LysM domain
AW03_012500	COG4195	phage-related replication protein
AW03_012510	COG3546	catalase activity
AW03_012520	COG2856	Zn peptidase
AW03_012530	COG1396	sequence-specific DNA binding
AW03_012550	COG1522	sequence-specific DNA binding
AW03_012560	COG1484	DNA-dependent DNA replication
AW03_012600	COG1595	DNA-templated transcription, initiation
AW03_012610	COG5484	DNA packaging
AW03_012610	COG3728	DNA packaging
AW03_012620	COG1783	phage Terminase large subunit
AW03_012630	COG5518	Phage portal protein
AW03_012640	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AW03_012650	COG4653	Phage capsid family
AW03_012730	COG5412	phage tail tape measure protein
AW03_012730	COG3953	SLT domain
AW03_012740	COG1652	LysM domain
AW03_012750	COG4193	domain, Protein
AW03_012770	COG3628	GPW Gp25 family protein
AW03_012780	COG3299	homolog of phage Mu protein gp47
AW03_012790	COG3778	Protein conserved in bacteria
AW03_012880	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW03_012880	COG3409	Peptidoglycan-binding domain 1 protein
AW03_012920	COG0306	phosphate transporter
AW03_012930	COG1392	Phosphate transport regulator
AW03_012940	COG0531	amino acid
AW03_012950	COG0346	lactoylglutathione lyase activity
AW03_012960	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AW03_012970	COG0463	Glycosyl transferase, family 2
AW03_012990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW03_013000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW03_013010	COG2362	D-Aminopeptidase
AW03_013020	COG0601	transmembrane transport
AW03_013030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW03_013040	COG0444	Belongs to the ABC transporter superfamily
AW03_013050	COG4166	transmembrane transport
AW03_013070	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW03_013080	COG4948	Mandelate Racemase Muconate Lactonizing
AW03_013090	COG0791	NLP P60 protein
AW03_013100	COG4608	Belongs to the ABC transporter superfamily
AW03_013110	COG2706	6-phosphogluconolactonase activity
AW03_013120	COG1834	amidinotransferase
AW03_013130	COG1607	acyl-coa hydrolase
AW03_013140	COG1017	nitric oxide dioxygenase activity
AW03_013140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW03_013160	COG2323	membrane
AW03_013170	COG2318	DinB family
AW03_013180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_013190	COG2076	Multidrug Resistance protein
AW03_013200	COG2076	Multidrug Resistance protein
AW03_013210	COG0788	formyltetrahydrofolate deformylase activity
AW03_013220	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW03_013230	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AW03_013240	COG1764	response to oxidative stress
AW03_013250	COG1846	Transcriptional regulator
AW03_013260	COG1764	response to oxidative stress
AW03_013270	COG0590	tRNA wobble adenosine to inosine editing
AW03_013290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AW03_013300	COG1404	Belongs to the peptidase S8 family
AW03_013310	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_013320	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW03_013330	COG1122	ATPase activity
AW03_013340	COG4721	ABC-type cobalt transport system, permease component
AW03_013360	COG0745	RESPONSE REGULATOR receiver
AW03_013370	COG3850	Histidine kinase
AW03_013370	COG5002	protein histidine kinase activity
AW03_013380	COG3212	peptidase
AW03_013390	COG3212	peptidase
AW03_013420	COG2239	Acts as a magnesium transporter
AW03_013430	COG0789	Transcriptional regulator
AW03_013460	COG1846	Transcriptional regulator
AW03_013470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW03_013480	COG0726	polysaccharide deacetylase
AW03_013490	COG1408	metallophosphoesterase
AW03_013510	COG0463	Glycosyl transferase, family 2
AW03_013520	COG3285	dna ligase
AW03_013520	COG1793	dna ligase
AW03_013530	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AW03_013540	COG5001	Diguanylate cyclase
AW03_013540	COG3300	MHYT domain
AW03_013550	COG0586	Pfam SNARE associated Golgi protein
AW03_013570	COG0861	Integral membrane protein TerC family
AW03_013580	COG1191	sigma factor activity
AW03_013620	COG0501	Belongs to the peptidase M48B family
AW03_013630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW03_013660	COG3594	Acyltransferase
AW03_013670	COG5002	protein histidine kinase activity
AW03_013680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW03_013700	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AW03_013710	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AW03_013720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW03_013730	COG0436	Aminotransferase
AW03_013740	COG1850	ribulose-bisphosphate carboxylase activity
AW03_013750	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AW03_013760	COG0235	Class ii aldolase
AW03_013770	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AW03_013780	COG3339	Conserved Protein
AW03_013810	COG3852	Histidine kinase
AW03_013820	COG1846	Transcriptional regulator
AW03_013830	COG1360	Flagellar Motor Protein
AW03_013840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW03_013850	COG0542	response to heat
AW03_013860	COG3949	Membrane
AW03_013870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AW03_013880	COG0720	synthase
AW03_013890	COG0602	queuosine metabolic process
AW03_013900	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AW03_013910	COG1388	LysM domain
AW03_013910	COG4641	Protein conserved in bacteria
AW03_013920	COG1388	LysM domain
AW03_013930	COG3858	chitin binding
AW03_013950	COG4873	Protein conserved in bacteria
AW03_013970	COG3773	Cell wall hydrolase
AW03_013980	COG2244	polysaccharide biosynthetic process
AW03_013990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_014000	COG2217	Heavy metal translocating P-type atpase
AW03_014010	COG0006	proline dipeptidase activity
AW03_014020	COG1609	Transcriptional regulator
AW03_014030	COG3711	transcriptional antiterminator
AW03_014040	COG1263	PTS System
AW03_014040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_014040	COG2190	(PTS) system
AW03_014050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_014060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AW03_014080	COG1533	DNA photolyase activity
AW03_014090	COG0456	acetyltransferase
AW03_014100	COG0840	transmembrane signaling receptor activity
AW03_014110	COG2084	Dehydrogenase
AW03_014120	COG2340	Cysteine-rich secretory protein family
AW03_014130	COG0768	penicillin binding
AW03_014140	COG4191	Histidine kinase
AW03_014150	COG0436	Aminotransferase
AW03_014170	COG0784	Response regulator, receiver
AW03_014170	COG0835	chemotaxis
AW03_014190	COG2814	Major facilitator Superfamily
AW03_014200	COG1376	ErfK ybiS ycfS ynhG family protein
AW03_014210	COG1408	metallophosphoesterase
AW03_014220	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_014230	COG2200	EAL domain
AW03_014250	COG4703	Protein of unknown function (DUF1797)
AW03_014260	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AW03_014280	COG0517	IMP dehydrogenase activity
AW03_014290	COG0583	DNA-binding transcription factor activity
AW03_014300	COG0716	FMN binding
AW03_014320	COG0716	FMN binding
AW03_014330	COG2171	N-acyltransferase activity
AW03_014340	COG1473	amidohydrolase
AW03_014360	COG0668	transmembrane transport
AW03_014370	COG0450	alkyl hydroperoxide reductase
AW03_014380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_014410	COG0746	molybdenum cofactor guanylyltransferase activity
AW03_014420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW03_014430	COG0303	'Molybdopterin
AW03_014440	COG1763	Mo-molybdopterin cofactor biosynthetic process
AW03_014450	COG0314	molybdopterin synthase activity
AW03_014460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AW03_014470	COG1132	(ABC) transporter
AW03_014480	COG1132	(ABC) transporter
AW03_014500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW03_014510	COG1136	(ABC) transporter
AW03_014520	COG0577	efflux transmembrane transporter activity
AW03_014530	COG1349	DNA-binding transcription factor activity
AW03_014540	COG1105	Belongs to the carbohydrate kinase PfkB family
AW03_014550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_014550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW03_014550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW03_014560	COG0681	Belongs to the peptidase S26 family
AW03_014580	COG0488	(ABC) transporter
AW03_014600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW03_014620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW03_014640	COG2309	aminopeptidase activity
AW03_014660	COG1077	Cell shape determining protein MreB Mrl
AW03_014670	COG2002	toxin-antitoxin pair type II binding
AW03_014680	COG3852	Histidine kinase
AW03_014690	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AW03_014690	COG2105	PFAM AIG2 family protein
AW03_014700	COG0569	domain protein
AW03_014710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AW03_014720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW03_014740	COG0561	phosphatase activity
AW03_014750	COG0242	peptide deformylase activity
AW03_014770	COG0497	DNA recombination
AW03_014780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW03_014790	COG0022	dehydrogenase e1 component
AW03_014800	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW03_014810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW03_014820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_014840	COG1982	Orn Lys Arg decarboxylase major
AW03_014850	COG4476	Belongs to the UPF0223 family
AW03_014860	COG4493	Belongs to the UPF0637 family
AW03_014880	COG0483	inositol monophosphate 1-phosphatase activity
AW03_014900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AW03_014940	COG1595	DNA-templated transcription, initiation
AW03_015000	COG4896	Protein conserved in bacteria
AW03_015020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AW03_015030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AW03_015040	COG2066	Belongs to the glutaminase family
AW03_015050	COG4838	Belongs to the UPF0358 family
AW03_015060	COG0772	Belongs to the SEDS family
AW03_015070	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AW03_015080	COG1612	heme a metabolic process
AW03_015090	COG0109	protoheme IX farnesyltransferase activity
AW03_015100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW03_015100	COG2010	Cytochrome c
AW03_015110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW03_015120	COG1845	cytochrome c oxidase, subunit III
AW03_015130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AW03_015140	COG3336	cytochrome c oxidase
AW03_015160	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AW03_015170	COG2340	Cysteine-rich secretory protein family
AW03_015200	COG3679	Belongs to the UPF0342 family
AW03_015210	COG4471	UPF0298 protein
AW03_015220	COG0742	ribosomal rna small subunit methyltransferase
AW03_015230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AW03_015240	COG3314	Sporulation integral membrane protein YlbJ
AW03_015250	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW03_015260	COG3480	Lon protease (S16) C-terminal proteolytic domain
AW03_015300	COG1399	metal-binding, possibly nucleic acid-binding protein
AW03_015310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AW03_015330	COG0454	-acetyltransferase
AW03_015340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW03_015350	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AW03_015360	COG2001	Belongs to the MraZ family
AW03_015370	COG0275	rRNA processing
AW03_015380	COG4839	cell division protein FtsL
AW03_015400	COG0768	penicillin binding
AW03_015410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW03_015420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW03_015430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AW03_015440	COG0772	Belongs to the SEDS family
AW03_015450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW03_015460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AW03_015470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AW03_015480	COG3879	Bacterial protein of unknown function (DUF881)
AW03_015490	COG3879	Bacterial protein of unknown function (DUF881)
AW03_015500	COG3856	small basic protein
AW03_015510	COG0849	cell division
AW03_015520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AW03_015530	COG1404	Belongs to the peptidase S8 family
AW03_015530	COG4412	M6 family metalloprotease domain protein
AW03_015550	COG1191	sigma factor activity
AW03_015560	COG1191	sigma factor activity
AW03_015570	COG1119	ATPase activity
AW03_015580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW03_015590	COG1873	PFAM PRC-barrel domain
AW03_015610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AW03_015620	COG1799	cell septum assembly
AW03_015630	COG0762	integral membrane protein
AW03_015640	COG2302	S4 RNA-binding domain
AW03_015650	COG3599	regulation of cell shape
AW03_015660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AW03_015670	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW03_015680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AW03_015690	COG0564	pseudouridine synthase activity
AW03_015700	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AW03_015710	COG2233	PERMEase
AW03_015720	COG0540	Belongs to the ATCase OTCase family
AW03_015730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AW03_015740	COG0505	Belongs to the CarA family
AW03_015750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AW03_015760	COG0543	2 iron, 2 sulfur cluster binding
AW03_015770	COG0167	dihydroorotate dehydrogenase activity
AW03_015780	COG0284	orotidine-5'-phosphate decarboxylase activity
AW03_015790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AW03_015810	COG0175	sulfate reduction
AW03_015820	COG0306	phosphate transporter
AW03_015830	COG2046	Belongs to the sulfate adenylyltransferase family
AW03_015840	COG0529	Catalyzes the synthesis of activated sulfate
AW03_015850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW03_015860	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AW03_015870	COG1648	precorrin-2 dehydrogenase activity
AW03_015890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW03_015900	COG1561	YicC-like family, N-terminal region
AW03_015910	COG2052	Domain of unknown function (DUF370)
AW03_015920	COG0194	GDP metabolic process
AW03_015930	COG1758	RNA polymerase activity
AW03_015940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW03_015950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW03_015960	COG0242	peptide deformylase activity
AW03_015970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AW03_015980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW03_015980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AW03_015990	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AW03_016000	COG0631	protein serine/threonine phosphatase activity
AW03_016010	COG0515	serine threonine protein kinase
AW03_016010	COG2815	serine threonine protein kinase
AW03_016020	COG1162	GTPase activity
AW03_016030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AW03_016040	COG1564	THIamine pyrophosphokinase
AW03_016050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AW03_016060	COG1302	Protein conserved in bacteria
AW03_016070	COG1461	Dihydroxyacetone kinase
AW03_016080	COG1760	l-serine dehydratase
AW03_016090	COG1760	l-serine dehydratase
AW03_016100	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AW03_016110	COG1349	DNA-binding transcription factor activity
AW03_016110	COG2050	protein possibly involved in aromatic compounds catabolism
AW03_016130	COG0416	fatty acid biosynthetic process
AW03_016140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW03_016150	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_016160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_016170	COG0571	ribonuclease III activity
AW03_016180	COG1196	nuclear chromosome segregation
AW03_016190	COG0552	protein localization to endoplasmic reticulum
AW03_016210	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AW03_016220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AW03_016230	COG0228	four-way junction DNA binding
AW03_016240	COG1837	Belongs to the UPF0109 family
AW03_016260	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AW03_016270	COG0336	Belongs to the RNA methyltransferase TrmD family
AW03_016280	COG0335	large ribosomal subunit rRNA binding
AW03_016290	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AW03_016300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AW03_016320	COG2257	FlhB HrpN YscU SpaS Family
AW03_016330	COG0045	succinate-CoA ligase (ADP-forming) activity
AW03_016340	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW03_016350	COG0758	DNA mediated transformation
AW03_016360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW03_016370	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AW03_016380	COG4974	Belongs to the 'phage' integrase family
AW03_016390	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AW03_016400	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AW03_016410	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AW03_016420	COG1815	bacterial-type flagellum-dependent cell motility
AW03_016430	COG1558	bacterial-type flagellum-dependent cell motility
AW03_016440	COG1677	Flagellar hook-basal body complex protein FliE
AW03_016450	COG1766	The M ring may be actively involved in energy transduction
AW03_016460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW03_016470	COG1317	bacterial-type flagellum organization
AW03_016480	COG1157	protein secretion by the type III secretion system
AW03_016490	COG2882	bacterial-type flagellum organization
AW03_016500	COG3334	PFAM MgtE intracellular
AW03_016510	COG3144	bacterial-type flagellum assembly
AW03_016520	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AW03_016530	COG4786	Flagellar basal body rod
AW03_016540	COG1580	Controls the rotational direction of flagella during chemotaxis
AW03_016550	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW03_016560	COG1776	CheC inhibitor of MCP methylation
AW03_016560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW03_016570	COG2201	protein-glutamate methylesterase activity
AW03_016580	COG3190	flagellar
AW03_016590	COG1338	Plays a role in the flagellum-specific transport system
AW03_016600	COG1987	bacterial-type flagellum assembly
AW03_016610	COG1684	flagellar biosynthetic protein fliR
AW03_016620	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW03_016630	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW03_016640	COG1419	protein localization to endoplasmic reticulum
AW03_016650	COG0455	bacterial-type flagellum organization
AW03_016660	COG2201	protein-glutamate methylesterase activity
AW03_016670	COG0643	Histidine kinase
AW03_016670	COG2198	Histidine kinase
AW03_016680	COG0835	chemotaxis
AW03_016690	COG1776	CheC inhibitor of MCP methylation
AW03_016700	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AW03_016710	COG1191	sigma factor activity
AW03_016730	COG0052	Belongs to the universal ribosomal protein uS2 family
AW03_016740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AW03_016750	COG0528	UMP kinase activity
AW03_016760	COG0233	cytoplasmic translational termination
AW03_016770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AW03_016780	COG4589	Belongs to the CDS family
AW03_016790	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AW03_016810	COG0750	zinc metalloprotease
AW03_016820	COG0442	prolyl-tRNA aminoacylation
AW03_016830	COG2176	DNA-directed DNA polymerase activity
AW03_016840	COG0779	Required for maturation of 30S ribosomal subunits
AW03_016850	COG0195	Participates in both transcription termination and antitermination
AW03_016860	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AW03_016870	COG1358	cellular component organization or biogenesis
AW03_016880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AW03_016890	COG1550	Protein conserved in bacteria
AW03_016900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AW03_016910	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AW03_016920	COG0196	riboflavin kinase activity
AW03_016930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AW03_016940	COG1185	polyribonucleotide nucleotidyltransferase activity
AW03_016950	COG0726	polysaccharide deacetylase
AW03_016960	COG0612	Peptidase, M16
AW03_016970	COG1873	PFAM PRC-barrel domain
AW03_016980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW03_016990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW03_017000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW03_017010	COG0527	aspartate kinase activity
AW03_017020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW03_017030	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW03_017040	COG0740	serine-type endopeptidase activity
AW03_017060	COG1674	ftsk spoiiie
AW03_017060	COG4980	gas vesicle protein
AW03_017070	COG2188	Transcriptional regulator
AW03_017080	COG2814	Major facilitator Superfamily
AW03_017090	COG0612	Peptidase, M16
AW03_017100	COG0612	Peptidase, M16
AW03_017110	COG0300	oxidoreductase activity
AW03_017140	COG1426	Protein conserved in bacteria
AW03_017150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AW03_017160	COG1058	Belongs to the CinA family
AW03_017160	COG1546	Belongs to the CinA family
AW03_017170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AW03_017180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW03_017190	COG1418	mRNA catabolic process
AW03_017200	COG1692	metallophosphoesterase
AW03_017210	COG2359	stage V sporulation protein S
AW03_017220	COG1063	alcohol dehydrogenase
AW03_017230	COG0156	8-amino-7-oxononanoate synthase activity
AW03_017240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW03_017250	COG4550	Control of competence regulator ComK, YlbF/YmcA
AW03_017270	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AW03_017280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AW03_017310	COG3226	Transcriptional regulator
AW03_017320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_017330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW03_017340	COG3321	synthase
AW03_017350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW03_017350	COG2070	2-Nitropropane dioxygenase
AW03_017360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_017370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW03_017380	COG3425	synthase
AW03_017390	COG1024	Enoyl-CoA hydratase
AW03_017400	COG1024	Enoyl-CoA hydratase
AW03_017410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_017410	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_017410	COG0300	oxidoreductase activity
AW03_017410	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_017410	COG3321	synthase
AW03_017420	COG0300	oxidoreductase activity
AW03_017420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_017420	COG3321	synthase
AW03_017420	COG4221	oxidoreductase activity
AW03_017430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_017430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW03_017430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_017430	COG3321	synthase
AW03_017430	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_017440	COG4221	oxidoreductase activity
AW03_017440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_017440	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_017440	COG3321	synthase
AW03_017450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW03_017450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_017450	COG3321	synthase
AW03_017450	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AW03_017460	COG2124	cytochrome p450
AW03_017480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_017490	COG1404	Belongs to the peptidase S8 family
AW03_017510	COG4195	phage-related replication protein
AW03_017520	COG1764	response to oxidative stress
AW03_017530	COG2076	Multidrug Resistance protein
AW03_017540	COG2076	Multidrug Resistance protein
AW03_017570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AW03_017580	COG1923	regulation of RNA biosynthetic process
AW03_017610	COG1780	Probably involved in ribonucleotide reductase function
AW03_017620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW03_017630	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW03_017640	COG4112	unkown
AW03_017650	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_017660	COG0464	growth
AW03_017670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW03_017680	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AW03_017690	COG0789	Transcriptional regulator
AW03_017700	COG0174	glutamine synthetase
AW03_017740	COG5444	nuclease activity
AW03_017800	COG4282	regulation of fungal-type cell wall biogenesis
AW03_017820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_017850	COG3655	Transcriptional regulator
AW03_017890	COG2211	Major facilitator Superfamily
AW03_017900	COG3507	Belongs to the glycosyl hydrolase 43 family
AW03_017910	COG1940	carbohydrate kinase activity
AW03_017930	COG2115	Belongs to the xylose isomerase family
AW03_017940	COG1070	Carbohydrate kinase
AW03_017950	COG1525	nuclease
AW03_017960	COG2814	Major facilitator Superfamily
AW03_017970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW03_017990	COG0756	dUTP diphosphatase activity
AW03_018020	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AW03_018080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW03_018100	COG3832	glyoxalase III activity
AW03_018120	COG0697	spore germination
AW03_018130	COG0531	amino acid
AW03_018190	COG4195	phage-related replication protein
AW03_018210	COG0346	lactoylglutathione lyase activity
AW03_018220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AW03_018230	COG1388	LysM domain
AW03_018240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AW03_018250	COG4224	UPF0291 protein
AW03_018260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AW03_018280	COG3763	UPF0154 protein
AW03_018290	COG0785	Cytochrome C biogenesis protein
AW03_018300	COG2201	protein-glutamate methylesterase activity
AW03_018310	COG4846	Membrane protein involved in cytochrome C biogenesis
AW03_018340	COG0071	Belongs to the small heat shock protein (HSP20) family
AW03_018370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AW03_018380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_018420	COG0824	Thioesterase
AW03_018440	COG4841	protein insertion into membrane
AW03_018450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW03_018460	COG1832	CoA-binding protein
AW03_018470	COG0187	DNA topoisomerase II activity
AW03_018480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW03_018500	COG1115	amino acid carrier protein
AW03_018510	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AW03_018540	COG5520	Belongs to the glycosyl hydrolase 30 family
AW03_018550	COG3507	Belongs to the glycosyl hydrolase 43 family
AW03_018560	COG2246	polysaccharide biosynthetic process
AW03_018570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW03_018580	COG0586	Pfam SNARE associated Golgi protein
AW03_018590	COG2404	hydrolase activity, acting on ester bonds
AW03_018600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AW03_018610	COG1024	Enoyl-CoA hydratase
AW03_018620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AW03_018630	COG0511	ligase activity, forming carbon-carbon bonds
AW03_018640	COG0439	Biotin carboxylase
AW03_018650	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_018660	COG1960	acyl-CoA dehydrogenase activity
AW03_018680	COG1649	PFAM Uncharacterised BCR, COG1649
AW03_018700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_018700	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AW03_018720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_018730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_018740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_018750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_018760	COG2027	D-alanyl-D-alanine carboxypeptidase
AW03_018770	COG2017	converts alpha-aldose to the beta-anomer
AW03_018780	COG0534	Mate efflux family protein
AW03_018800	COG0582	viral genome integration into host DNA
AW03_018810	COG0166	Belongs to the GPI family
AW03_018820	COG0405	Gamma-glutamyltransferase
AW03_018830	COG0583	DNA-binding transcription factor activity
AW03_018840	COG0604	alcohol dehydrogenase
AW03_018850	COG0493	'glutamate synthase
AW03_018860	COG0070	glutamate synthase
AW03_018860	COG0069	glutamate synthase activity
AW03_018860	COG0067	glutamate synthase
AW03_018870	COG0583	DNA-binding transcription factor activity
AW03_018880	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW03_018890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW03_018910	COG0300	oxidoreductase activity
AW03_018920	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AW03_018940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_018950	COG2814	Major facilitator Superfamily
AW03_018960	COG1070	Carbohydrate kinase
AW03_018970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW03_018980	COG0243	molybdopterin cofactor binding
AW03_019020	COG5278	phosphoserine phosphatase activity
AW03_019020	COG0840	transmembrane signaling receptor activity
AW03_019030	COG2368	4-hydroxyphenylacetate
AW03_019040	COG4305	rare lipoprotein A
AW03_019050	COG3619	membrane
AW03_019060	COG3866	Pectate lyase
AW03_019070	COG2135	peptidase activity
AW03_019100	COG2140	Oxalate decarboxylase
AW03_019130	COG2720	vancomycin resistance protein
AW03_019150	COG3655	Transcriptional regulator
AW03_019160	COG3739	integral membrane protein
AW03_019170	COG0583	DNA-binding transcription factor activity
AW03_019180	COG0697	spore germination
AW03_019200	COG0693	protein deglycase activity
AW03_019210	COG2367	Beta-lactamase
AW03_019240	COG3848	Pyruvate phosphate dikinase
AW03_019240	COG0574	Belongs to the PEP-utilizing enzyme family
AW03_019250	COG0726	polysaccharide deacetylase
AW03_019300	COG5444	nuclease activity
AW03_019310	COG4282	regulation of fungal-type cell wall biogenesis
AW03_019320	COG1231	oxidoreductase activity
AW03_019340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW03_019350	COG0662	Cupin 2, conserved barrel domain protein
AW03_019350	COG2207	Transcriptional regulator
AW03_019360	COG0456	acetyltransferase
AW03_019370	COG1309	transcriptional regulator
AW03_019380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_019390	COG3708	Transcriptional regulator
AW03_019400	COG2378	regulation of single-species biofilm formation
AW03_019420	COG0640	Transcriptional regulator
AW03_019430	COG0741	lytic transglycosylase activity
AW03_019440	COG2322	membrane
AW03_019470	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW03_019480	COG3239	Fatty acid desaturase
AW03_019490	COG4585	Histidine kinase
AW03_019500	COG2197	response regulator
AW03_019510	COG1388	LysM domain
AW03_019510	COG3584	3D domain protein
AW03_019520	COG0514	ATP-dependent DNA helicase (RecQ)
AW03_019540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW03_019550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW03_019580	COG0071	Belongs to the small heat shock protein (HSP20) family
AW03_019630	COG1012	belongs to the aldehyde dehydrogenase family
AW03_019640	COG1657	PFAM Prenyltransferase squalene oxidase
AW03_019650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW03_019660	COG0733	neurotransmitter:sodium symporter activity
AW03_019670	COG0385	Bile acid
AW03_019680	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW03_019690	COG0567	Dehydrogenase, E1 component
AW03_019700	COG4548	von Willebrand factor, type A
AW03_019710	COG0714	Associated with various cellular activities
AW03_019730	COG2032	superoxide dismutase activity
AW03_019740	COG0791	NLP P60 protein
AW03_019740	COG1388	LysM domain
AW03_019750	COG1819	glycosyl
AW03_019760	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW03_019780	COG0534	Mate efflux family protein
AW03_019790	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_019800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW03_019810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW03_019830	COG2962	Rard protein
AW03_019860	COG2610	gluconate transmembrane transporter activity
AW03_019870	COG1942	4-Oxalocrotonate Tautomerase
AW03_019880	COG1733	regulation of RNA biosynthetic process
AW03_019890	COG0778	Nitroreductase
AW03_019900	COG0400	carboxylic ester hydrolase activity
AW03_019910	COG0346	lactoylglutathione lyase activity
AW03_019930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW03_019940	COG0793	Belongs to the peptidase S41A family
AW03_019940	COG3409	Peptidoglycan-binding domain 1 protein
AW03_019950	COG2226	methyltransferase
AW03_019970	COG1876	peptidase activity
AW03_019980	COG0813	purine-nucleoside phosphorylase activity
AW03_020010	COG0671	phosphoesterase, PA-phosphatase related
AW03_020050	COG4479	Belongs to the UPF0346 family
AW03_020070	COG1509	lysine 2,3-aminomutase activity
AW03_020080	COG0456	acetyltransferase
AW03_020090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW03_020100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AW03_020110	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AW03_020120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW03_020140	COG0456	acetyltransferase
AW03_020150	COG0463	Glycosyl transferase, family 2
AW03_020180	COG4641	Protein conserved in bacteria
AW03_020190	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
AW03_020200	COG1086	Polysaccharide biosynthesis protein
AW03_020210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW03_020220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW03_020230	COG1846	Transcriptional regulator
AW03_020240	COG0534	Mate efflux family protein
AW03_020260	COG4698	Protein conserved in bacteria
AW03_020270	COG2755	lipolytic protein G-D-S-L family
AW03_020280	COG1999	signal sequence binding
AW03_020300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AW03_020310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW03_020320	COG1272	protein, Hemolysin III
AW03_020330	COG0204	Acyl-transferase
AW03_020340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW03_020350	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AW03_020360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW03_020380	COG2136	Putative SAM-dependent methyltransferase
AW03_020380	COG2521	methyltransferase
AW03_020400	COG0129	dihydroxy-acid dehydratase activity
AW03_020420	COG1413	lyase activity
AW03_020430	COG1418	mRNA catabolic process
AW03_020440	COG0386	Belongs to the glutathione peroxidase family
AW03_020450	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AW03_020460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW03_020470	COG1278	Cold shock
AW03_020510	COG0328	RNA-DNA hybrid ribonuclease activity
AW03_020520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AW03_020530	COG0328	RNA-DNA hybrid ribonuclease activity
AW03_020550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW03_020580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW03_020590	COG1755	Isoprenylcysteine carboxyl methyltransferase
AW03_020600	COG3424	synthase
AW03_020610	COG2233	PERMEase
AW03_020620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW03_020630	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AW03_020650	COG0800	Aldolase
AW03_020660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW03_020670	COG1609	Transcriptional regulator
AW03_020680	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AW03_020690	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_020700	COG1199	ATP-dependent helicase activity
AW03_020720	COG0116	Belongs to the methyltransferase superfamily
AW03_020740	COG4474	Belongs to the UPF0398 family
AW03_020750	COG3359	exonuclease
AW03_020760	COG1111	helicase
AW03_020760	COG1205	dead DEAH box helicase
AW03_020770	COG2190	(PTS) system
AW03_020780	COG0071	Belongs to the small heat shock protein (HSP20) family
AW03_020850	COG3331	DNA recombination
AW03_020860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW03_020860	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW03_020880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AW03_020890	COG3935	DnaD domain protein
AW03_020900	COG0017	Asparaginyl-tRNA synthetase
AW03_020910	COG0436	Aminotransferase
AW03_020920	COG5353	protein conserved in bacteria
AW03_020940	COG1199	ATP-dependent helicase activity
AW03_020940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW03_020950	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AW03_020960	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AW03_020970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AW03_020980	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AW03_020980	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AW03_020990	COG0617	tRNA 3'-terminal CCA addition
AW03_021000	COG0438	transferase activity, transferring glycosyl groups
AW03_021010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW03_021020	COG1803	Methylglyoxal synthase
AW03_021030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AW03_021040	COG1694	Mazg nucleotide pyrophosphohydrolase
AW03_021050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_021070	COG4347	Protein of unknown function (DUF1405)
AW03_021080	COG2010	Cytochrome c
AW03_021080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AW03_021090	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AW03_021100	COG0723	plastoquinol--plastocyanin reductase activity
AW03_021120	COG5582	Belongs to the UPF0302 family
AW03_021130	COG0457	Tetratricopeptide repeat
AW03_021140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AW03_021150	COG0287	Prephenate dehydrogenase
AW03_021160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW03_021170	COG0159	tryptophan synthase activity
AW03_021180	COG0133	tryptophan synthase activity
AW03_021190	COG0135	phosphoribosylanthranilate isomerase activity
AW03_021210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AW03_021220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW03_021230	COG4401	Chorismate mutase type I
AW03_021240	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AW03_021250	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AW03_021260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW03_021270	COG0105	UTP biosynthetic process
AW03_021280	COG0142	geranyltranstransferase activity
AW03_021290	COG2226	methyltransferase
AW03_021300	COG0142	geranyltranstransferase activity
AW03_021320	COG0302	gtp cyclohydrolase
AW03_021330	COG0776	regulation of translation
AW03_021340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW03_021370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AW03_021380	COG1160	GTP binding
AW03_021430	COG1304	FMN binding
AW03_021440	COG0539	negative regulation of cytoplasmic translation
AW03_021450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AW03_021470	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AW03_021480	COG2959	enzyme of heme biosynthesis
AW03_021490	COG3773	Cell wall hydrolase
AW03_021490	COG3409	Peptidoglycan-binding domain 1 protein
AW03_021500	COG2339	peptidase activity
AW03_021510	COG0492	ferredoxin-NADP+ reductase activity
AW03_021520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW03_021530	COG4862	establishment of competence for transformation
AW03_021540	COG1408	metallophosphoesterase
AW03_021560	COG1388	LysM domain
AW03_021570	COG1266	CAAX protease self-immunity
AW03_021580	COG0514	ATP-dependent DNA helicase (RecQ)
AW03_021590	COG4955	Helix-turn-helix domain
AW03_021600	COG1141	Ferredoxin
AW03_021610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AW03_021620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW03_021630	COG0710	3-dehydroquinate dehydratase activity
AW03_021650	COG1595	DNA-templated transcription, initiation
AW03_021660	COG5002	protein histidine kinase activity
AW03_021670	COG0745	RESPONSE REGULATOR receiver
AW03_021680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW03_021690	COG1333	cytochrome c biogenesis protein
AW03_021700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_021710	COG1187	pseudouridine synthase activity
AW03_021720	COG0700	Nucleoside recognition
AW03_021730	COG2715	membrane protein required for spore maturation
AW03_021740	COG1686	Belongs to the peptidase S11 family
AW03_021760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AW03_021770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AW03_021780	COG1547	Domain of unknown function (DUF309)
AW03_021790	COG0456	acetyltransferase
AW03_021800	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AW03_021810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AW03_021810	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AW03_021820	COG0307	riboflavin synthase, alpha
AW03_021830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW03_021830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW03_021850	COG0681	Belongs to the peptidase S26 family
AW03_021860	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AW03_021880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AW03_021890	COG4086	secreted protein
AW03_021900	COG0019	diaminopimelate decarboxylase activity
AW03_021910	COG0697	spore germination
AW03_021940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW03_021980	COG1191	sigma factor activity
AW03_021990	COG2172	sigma factor antagonist activity
AW03_022000	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_022010	COG1686	Belongs to the peptidase S11 family
AW03_022020	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AW03_022030	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AW03_022040	COG4974	Belongs to the 'phage' integrase family
AW03_022060	COG0735	belongs to the Fur family
AW03_022070	COG1300	Membrane
AW03_022090	COG0281	malic enzyme
AW03_022100	COG1757	Na H antiporter
AW03_022110	COG1027	Aspartate ammonia-lyase
AW03_022120	COG0252	asparaginase activity
AW03_022130	COG1396	sequence-specific DNA binding
AW03_022140	COG1379	DNA repair
AW03_022150	COG0494	nUDIX hydrolase
AW03_022170	COG0667	Aldo Keto reductase
AW03_022190	COG1073	alpha beta
AW03_022210	COG4918	Iron-sulphur cluster biosynthesis
AW03_022220	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW03_022220	COG0456	acetyltransferase
AW03_022230	COG2329	Antibiotic biosynthesis monooxygenase
AW03_022240	COG0456	acetyltransferase
AW03_022260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW03_022280	COG2211	Major facilitator Superfamily
AW03_022300	COG0346	lactoylglutathione lyase activity
AW03_022310	COG1072	(Pantothenic acid kinase))
AW03_022320	COG3048	D-serine ammonia-lyase activity
AW03_022330	COG0300	oxidoreductase activity
AW03_022340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_022350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW03_022360	COG4187	Peptidase family M20/M25/M40
AW03_022370	COG1902	pentaerythritol trinitrate reductase activity
AW03_022380	COG0596	Alpha beta hydrolase
AW03_022400	COG1234	tRNA 3'-trailer cleavage
AW03_022410	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW03_022420	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AW03_022430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW03_022450	COG0706	membrane insertase activity
AW03_022460	COG3361	conserved protein (COG2071)
AW03_022470	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW03_022480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AW03_022490	COG0346	lactoylglutathione lyase activity
AW03_022510	COG1376	ErfK ybiS ycfS ynhG family protein
AW03_022520	COG4129	membrane
AW03_022530	COG1126	abc transporter atp-binding protein
AW03_022540	COG0765	amino acid transport
AW03_022550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_022570	COG1597	lipid kinase activity
AW03_022580	COG2814	Major facilitator Superfamily
AW03_022590	COG0789	Transcriptional regulator
AW03_022590	COG4978	Transcriptional regulator
AW03_022600	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW03_022610	COG0022	dehydrogenase e1 component
AW03_022620	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW03_022630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW03_022640	COG3426	butyrate kinase activity
AW03_022650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW03_022660	COG0280	phosphate acetyltransferase
AW03_022670	COG3290	protein histidine kinase activity
AW03_022670	COG3829	transcription factor binding
AW03_022690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AW03_022700	COG2079	MmgE PrpD family protein
AW03_022710	COG0372	Belongs to the citrate synthase family
AW03_022720	COG1960	acyl-CoA dehydrogenase activity
AW03_022730	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW03_022740	COG0183	Belongs to the thiolase family
AW03_022750	COG0584	glycerophosphoryl diester phosphodiesterase
AW03_022760	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_022780	COG1902	pentaerythritol trinitrate reductase activity
AW03_022800	COG0745	RESPONSE REGULATOR receiver
AW03_022810	COG0750	zinc metalloprotease
AW03_022820	COG0497	DNA recombination
AW03_022830	COG1438	arginine binding
AW03_022840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AW03_022850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AW03_022860	COG0142	geranyltranstransferase activity
AW03_022870	COG1722	exodeoxyribonuclease VII activity
AW03_022880	COG1570	exodeoxyribonuclease VII activity
AW03_022890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AW03_022900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW03_022910	COG1302	Protein conserved in bacteria
AW03_022920	COG0439	Biotin carboxylase
AW03_022930	COG0511	ligase activity, forming carbon-carbon bonds
AW03_023010	COG3854	ATPases associated with a variety of cellular activities
AW03_023030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AW03_023040	COG0006	proline dipeptidase activity
AW03_023050	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AW03_023070	COG3872	metal-dependent enzyme
AW03_023090	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW03_023100	COG1321	iron dependent repressor
AW03_023110	COG0095	Lipoate-protein ligase
AW03_023120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW03_023130	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AW03_023140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AW03_023150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AW03_023160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW03_023190	COG1396	sequence-specific DNA binding
AW03_023210	COG0681	Belongs to the peptidase S26 family
AW03_023260	COG4940	Competence protein ComGF
AW03_023280	COG4970	Tfp pilus assembly protein FimT
AW03_023290	COG4537	Required for transformation and DNA binding
AW03_023300	COG1459	type II secretion system
AW03_023310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AW03_023320	COG0598	Magnesium transport protein CorA
AW03_023330	COG1253	flavin adenine dinucleotide binding
AW03_023340	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_023350	COG1393	Belongs to the ArsC family
AW03_023370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_023390	COG0011	TIGRFAM Protein of
AW03_023410	COG2866	Carboxypeptidase
AW03_023420	COG1368	sulfuric ester hydrolase activity
AW03_023430	COG1940	carbohydrate kinase activity
AW03_023440	COG4483	Protein conserved in bacteria
AW03_023450	COG0457	Tetratricopeptide repeat
AW03_023450	COG0705	Rhomboid family
AW03_023470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AW03_023480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AW03_023490	COG0438	transferase activity, transferring glycosyl groups
AW03_023520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW03_023530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AW03_023540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AW03_023550	COG0581	inorganic phosphate transmembrane transporter activity
AW03_023560	COG0573	inorganic phosphate transmembrane transporter activity
AW03_023570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW03_023590	COG0477	Major facilitator Superfamily
AW03_023600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW03_023610	COG2839	Protein conserved in bacteria
AW03_023620	COG5521	maltodextrose utilization protein MalA
AW03_023630	COG1388	LysM domain
AW03_023640	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AW03_023650	COG4709	membrane
AW03_023660	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AW03_023670	COG0735	belongs to the Fur family
AW03_023680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_023700	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AW03_023710	COG0513	Belongs to the DEAD box helicase family
AW03_023730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AW03_023740	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW03_023750	COG2384	SAM-dependent methyltransferase
AW03_023760	COG2010	Cytochrome c
AW03_023770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AW03_023780	COG0358	DNA primase activity
AW03_023790	COG1671	Belongs to the UPF0178 family
AW03_023800	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AW03_023810	COG0517	IMP dehydrogenase activity
AW03_023820	COG0751	glycine-tRNA ligase activity
AW03_023830	COG0752	glycyl-tRNA synthetase alpha subunit
AW03_023840	COG1381	Involved in DNA repair and RecF pathway recombination
AW03_023860	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AW03_023870	COG0295	cytidine deaminase activity
AW03_023880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AW03_023890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AW03_023900	COG1480	7TM receptor with intracellular HD hydrolase
AW03_023920	COG1702	phosphate starvation-inducible protein PhoH
AW03_023930	COG0561	phosphatase activity
AW03_023960	COG4864	UPF0365 protein
AW03_023970	COG1030	water channel activity
AW03_023980	COG1610	YqeY-like protein
AW03_023990	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AW03_024000	COG1283	sodium-dependent phosphate transmembrane transporter activity
AW03_024010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW03_024020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AW03_024030	COG2264	protein methyltransferase activity
AW03_024040	COG0484	heat shock protein binding
AW03_024050	COG0443	Heat shock 70 kDa protein
AW03_024060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AW03_024070	COG1420	regulation of RNA biosynthetic process
AW03_024080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW03_024090	COG0481	GTPase activity
AW03_024110	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_024120	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AW03_024130	COG0268	Binds directly to 16S ribosomal RNA
AW03_024150	COG1466	dna polymerase III delta subunit
AW03_024170	COG0658	competence protein
AW03_024170	COG2333	competence protein COMEC
AW03_024180	COG2131	deaminase
AW03_024190	COG1596	polysaccharide export
AW03_024190	COG1555	photosystem II stabilization
AW03_024200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW03_024210	COG2226	methyltransferase
AW03_024220	COG0799	negative regulation of ribosome biogenesis
AW03_024230	COG1713	HD superfamily hydrolase involved in NAD metabolism
AW03_024240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AW03_024250	COG1534	Rna-binding protein
AW03_024260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AW03_024270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AW03_024280	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AW03_024300	COG2755	lipolytic protein G-D-S-L family
AW03_024310	COG3409	Peptidoglycan-binding domain 1 protein
AW03_024310	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW03_024320	COG0398	Pfam SNARE associated Golgi protein
AW03_024330	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AW03_024350	COG3209	COG3209 Rhs family protein
AW03_024380	COG3223	Belongs to the PsiE family
AW03_024390	COG0642	Histidine kinase
AW03_024390	COG5002	protein histidine kinase activity
AW03_024400	COG0745	RESPONSE REGULATOR receiver
AW03_024410	COG2311	Membrane
AW03_024420	COG0454	-acetyltransferase
AW03_024430	COG1733	regulation of RNA biosynthetic process
AW03_024440	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_024490	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW03_024490	COG3409	Peptidoglycan-binding domain 1 protein
AW03_024500	COG4824	toxin secretion phage lysis holin
AW03_024540	COG0563	adenylate kinase activity
AW03_024560	COG2856	Zn peptidase
AW03_024570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AW03_024580	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW03_024600	COG1846	Transcriptional regulator
AW03_024610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW03_024630	COG0457	Tetratricopeptide repeat
AW03_024640	COG5444	nuclease activity
AW03_024700	COG4978	Transcriptional regulator
AW03_024700	COG0789	Transcriptional regulator
AW03_024710	COG2814	Major facilitator Superfamily
AW03_024720	COG0456	acetyltransferase
AW03_024730	COG1253	flavin adenine dinucleotide binding
AW03_024750	COG0697	spore germination
AW03_024760	COG0583	DNA-binding transcription factor activity
AW03_024770	COG2072	flavoprotein involved in K transport
AW03_024780	COG1230	cation diffusion facilitator family transporter
AW03_024790	COG1942	4-Oxalocrotonate Tautomerase
AW03_024800	COG0583	DNA-binding transcription factor activity
AW03_024810	COG1114	Component of the transport system for branched-chain amino acids
AW03_024820	COG1687	branched-chain amino acid
AW03_024830	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AW03_024840	COG1522	sequence-specific DNA binding
AW03_024850	COG2732	(Barnase) inhibitor
AW03_024860	COG2124	cytochrome p450
AW03_024870	COG1335	isochorismatase
AW03_024900	COG2318	DinB family
AW03_024920	COG2070	2-Nitropropane dioxygenase
AW03_024930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AW03_024950	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW03_024960	COG1595	DNA-templated transcription, initiation
AW03_024970	COG0667	Aldo Keto reductase
AW03_024980	COG3409	Peptidoglycan-binding domain 1 protein
AW03_024990	COG5566	PFAM Mor transcription activator
AW03_025000	COG0596	Alpha beta hydrolase
AW03_025010	COG4991	sh3 domain protein
AW03_025020	COG4991	sh3 domain protein
AW03_025030	COG0346	lactoylglutathione lyase activity
AW03_025050	COG5577	PFAM Coat F domain
AW03_025060	COG1063	alcohol dehydrogenase
AW03_025080	COG5577	PFAM Coat F domain
AW03_025090	COG0789	Transcriptional regulator
AW03_025110	COG1064	alcohol dehydrogenase
AW03_025120	COG0693	protein deglycase activity
AW03_025130	COG1621	beta-fructofuranosidase activity
AW03_025140	COG3716	PTS system mannose fructose sorbose family IID component
AW03_025150	COG3715	PTS system
AW03_025160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_025170	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_025180	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AW03_025180	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW03_025190	COG1113	amino acid transport
AW03_025200	COG1280	lysine exporter protein (LysE YggA)
AW03_025210	COG1378	Sugar-specific transcriptional regulator TrmB
AW03_025220	COG1595	DNA-templated transcription, initiation
AW03_025240	COG2755	lipolytic protein G-D-S-L family
AW03_025240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AW03_025260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AW03_025260	COG2124	cytochrome p450
AW03_025270	COG1309	transcriptional regulator
AW03_025280	COG2226	methyltransferase
AW03_025310	COG2116	formate transmembrane transporter activity
AW03_025320	COG5609	conserved protein (DUF2294)
AW03_025330	COG3383	formate dehydrogenase (NAD+) activity
AW03_025340	COG2427	Protein of unknown function (DUF1641)
AW03_025360	COG0626	cystathionine gamma-synthase activity
AW03_025370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW03_025380	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AW03_025390	COG2226	methyltransferase
AW03_025420	COG0768	penicillin binding
AW03_025430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AW03_025440	COG0572	uridine kinase
AW03_025480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW03_025490	COG3906	Belongs to the UPF0473 family
AW03_025500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AW03_025510	COG4472	Bacterial protein of unknown function (DUF965)
AW03_025520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW03_025530	COG0628	permease
AW03_025540	COG1126	abc transporter atp-binding protein
AW03_025550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_025560	COG0765	amino acid transport
AW03_025570	COG0765	amino acid transport
AW03_025600	COG3881	PFAM PRC-barrel domain
AW03_025610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AW03_025620	COG0457	Tetratricopeptide repeat
AW03_025630	COG0482	sulfurtransferase activity
AW03_025640	COG1104	cysteine desulfurase activity
AW03_025650	COG1959	2 iron, 2 sulfur cluster binding
AW03_025660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AW03_025670	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AW03_025680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AW03_025690	COG0124	histidyl-tRNA synthetase
AW03_025710	COG3103	Sh3 type 3 domain protein
AW03_025710	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_025710	COG4991	sh3 domain protein
AW03_025720	COG1490	D-aminoacyl-tRNA deacylase activity
AW03_025730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW03_025740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW03_025750	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AW03_025750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AW03_025760	COG5416	Lipopolysaccharide assembly protein A domain
AW03_025770	COG0490	domain, Protein
AW03_025780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW03_025780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW03_025800	COG2244	polysaccharide biosynthetic process
AW03_025810	COG2323	membrane
AW03_025830	COG1862	Preprotein translocase
AW03_025840	COG0343	queuine tRNA-ribosyltransferase activity
AW03_025850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AW03_025870	COG2255	four-way junction helicase activity
AW03_025880	COG0632	four-way junction helicase activity
AW03_025900	COG2814	Major facilitator Superfamily
AW03_025910	COG0673	inositol 2-dehydrogenase activity
AW03_025920	COG2112	serine threonine protein kinase
AW03_025950	COG1115	amino acid carrier protein
AW03_025960	COG0217	transcriptional regulatory protein
AW03_025980	COG1388	LysM domain
AW03_025990	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AW03_026000	COG0157	Belongs to the NadC ModD family
AW03_026010	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AW03_026020	COG1104	cysteine desulfurase activity
AW03_026030	COG1827	regulation of RNA biosynthetic process
AW03_026040	COG0077	Prephenate dehydratase
AW03_026050	COG4492	Belongs to the UPF0735 family
AW03_026060	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AW03_026070	COG3290	protein histidine kinase activity
AW03_026080	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AW03_026090	COG2868	ribosomal protein
AW03_026100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AW03_026110	COG1994	Peptidase M50
AW03_026120	COG0739	heme binding
AW03_026130	COG2894	cell division
AW03_026140	COG0850	regulation of cytokinetic process
AW03_026150	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AW03_026160	COG1792	Involved in formation and maintenance of cell shape
AW03_026170	COG1077	Cell shape determining protein MreB Mrl
AW03_026190	COG2003	Belongs to the UPF0758 family
AW03_026200	COG0424	maF-like protein
AW03_026220	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AW03_026230	COG0285	dihydrofolate synthase activity
AW03_026240	COG0525	valine-tRNA ligase activity
AW03_026260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW03_026270	COG1388	LysM domain
AW03_026280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AW03_026290	COG0113	porphobilinogen synthase activity
AW03_026300	COG1587	Uroporphyrinogen-III synthase
AW03_026310	COG0181	hydroxymethylbilane synthase activity
AW03_026320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW03_026330	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AW03_026350	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AW03_026360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AW03_026370	COG1067	ATP-dependent peptidase activity
AW03_026370	COG0470	DNA polymerase III
AW03_026380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AW03_026390	COG0544	peptidyl-prolyl cis-trans isomerase activity
AW03_026400	COG1477	protein flavinylation
AW03_026400	COG0457	Tetratricopeptide repeat
AW03_026410	COG0066	3-isopropylmalate dehydratase activity
AW03_026420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AW03_026430	COG0473	3-isopropylmalate dehydrogenase activity
AW03_026440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AW03_026450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW03_026460	COG0440	acetolactate synthase activity
AW03_026470	COG0028	Belongs to the TPP enzyme family
AW03_026490	COG0454	-acetyltransferase
AW03_026500	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AW03_026510	COG0622	Phosphoesterase
AW03_026520	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AW03_026530	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AW03_026540	COG5401	PFAM Sporulation and spore germination
AW03_026550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AW03_026560	COG1846	Transcriptional regulator
AW03_026570	COG2197	response regulator
AW03_026580	COG0824	Thioesterase
AW03_026590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AW03_026600	COG1053	succinate dehydrogenase
AW03_026610	COG2009	succinate dehydrogenase
AW03_026620	COG1719	4-vinyl reductase, 4VR
AW03_026630	COG0527	aspartate kinase activity
AW03_026640	COG0322	excinuclease ABC activity
AW03_026650	COG3118	belongs to the thioredoxin family
AW03_026660	COG3534	alpha-L-arabinofuranosidase
AW03_026680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AW03_026690	COG2086	electron transfer activity
AW03_026700	COG1024	Enoyl-CoA hydratase
AW03_026710	COG1309	transcriptional regulator
AW03_026720	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_026730	COG3766	membrane
AW03_026740	COG1193	negative regulation of DNA recombination
AW03_026750	COG1796	DNA polymerase
AW03_026750	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW03_026760	COG1286	toxin biosynthetic process
AW03_026770	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AW03_026780	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AW03_026790	COG0072	phenylalanine-tRNA ligase activity
AW03_026790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW03_026800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AW03_026810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW03_026830	COG3835	regulator
AW03_026840	COG0277	FAD linked oxidase domain protein
AW03_026850	COG0247	lactate metabolic process
AW03_026860	COG0346	lactoylglutathione lyase activity
AW03_026870	COG1966	Carbon starvation protein
AW03_026880	COG3534	alpha-L-arabinofuranosidase
AW03_026890	COG0395	ABC-type sugar transport system, permease component
AW03_026900	COG1175	transmembrane transport
AW03_026910	COG1653	transport
AW03_026920	COG0371	Dehydrogenase
AW03_026930	COG0647	UMP catabolic process
AW03_026940	COG0235	Class ii aldolase
AW03_026950	COG1069	ribulokinase activity
AW03_026960	COG2160	L-arabinose isomerase activity
AW03_026970	COG3507	Belongs to the glycosyl hydrolase 43 family
AW03_026980	COG1363	Peptidase, m42
AW03_027000	COG3326	Membrane
AW03_027010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AW03_027020	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AW03_027030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AW03_027050	COG1346	cytolysis
AW03_027060	COG1380	Effector of murein hydrolase LrgA
AW03_027070	COG3279	Response regulator of the LytR AlgR family
AW03_027080	COG3275	phosphorelay sensor kinase activity
AW03_027100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW03_027120	COG0398	Pfam SNARE associated Golgi protein
AW03_027130	COG1484	DNA-dependent DNA replication
AW03_027140	COG3611	Membrane attachment protein
AW03_027150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AW03_027160	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW03_027170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW03_027180	COG1733	regulation of RNA biosynthetic process
AW03_027190	COG2814	Major facilitator Superfamily
AW03_027200	COG0656	L-ascorbic acid biosynthetic process
AW03_027210	COG0237	dephospho-CoA kinase activity
AW03_027220	COG1971	Probably functions as a manganese efflux pump
AW03_027230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AW03_027240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW03_027240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW03_027250	COG5002	protein histidine kinase activity
AW03_027260	COG0745	RESPONSE REGULATOR receiver
AW03_027270	COG0039	L-malate dehydrogenase activity
AW03_027280	COG0538	isocitrate dehydrogenase activity
AW03_027290	COG0372	Belongs to the citrate synthase family
AW03_027300	COG2707	UPF0756 membrane protein
AW03_027310	COG0628	permease
AW03_027320	COG3030	protein affecting phage T7 exclusion by the F plasmid
AW03_027330	COG0469	pyruvate kinase activity
AW03_027340	COG0205	6-phosphofructokinase activity
AW03_027350	COG0825	malonyl-CoA metabolic process
AW03_027360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AW03_027370	COG0281	malic enzyme
AW03_027380	COG0587	DNA-directed DNA polymerase activity
AW03_027420	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AW03_027440	COG4109	DRTGG domain
AW03_027450	COG0730	response to heat
AW03_027460	COG1473	amidohydrolase
AW03_027470	COG0196	riboflavin kinase activity
AW03_027480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_027490	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AW03_027500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_027510	COG1126	abc transporter atp-binding protein
AW03_027520	COG0765	amino acid transport
AW03_027530	COG0765	amino acid transport
AW03_027540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_027550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_027560	COG0454	-acetyltransferase
AW03_027570	COG0583	DNA-binding transcription factor activity
AW03_027580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AW03_027590	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_027610	COG0165	Argininosuccinate lyase
AW03_027620	COG0137	argininosuccinate synthase activity
AW03_027630	COG0521	Mo-molybdopterin cofactor biosynthetic process
AW03_027640	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AW03_027650	COG0827	DNA restriction-modification system
AW03_027660	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AW03_027670	COG3874	Sporulation protein YtfJ
AW03_027690	COG1714	RDD family
AW03_027700	COG0616	signal peptide processing
AW03_027710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AW03_027720	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AW03_027730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW03_027750	COG0301	tRNA thio-modification
AW03_027760	COG1104	cysteine desulfurase activity
AW03_027770	COG1114	Component of the transport system for branched-chain amino acids
AW03_027780	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AW03_027790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW03_027800	COG1309	transcriptional regulator
AW03_027810	COG1956	GAF domain-containing protein
AW03_027820	COG2203	Gaf domain
AW03_027820	COG2199	diguanylate cyclase activity
AW03_027830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AW03_027850	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AW03_027860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW03_027870	COG0454	-acetyltransferase
AW03_027880	COG0517	IMP dehydrogenase activity
AW03_027890	COG0123	including yeast histone deacetylase and acetoin utilization protein
AW03_027900	COG1360	Flagellar Motor Protein
AW03_027910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW03_027920	COG1609	Transcriptional regulator
AW03_027930	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AW03_027930	COG1605	Chorismate mutase
AW03_027940	COG3118	belongs to the thioredoxin family
AW03_027950	COG4980	gas vesicle protein
AW03_027960	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AW03_027970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AW03_027980	COG1674	ftsk spoiiie
AW03_027990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW03_028000	COG4848	Belongs to the UPF0354 family
AW03_028010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_028030	COG1363	Peptidase, m42
AW03_028040	COG5584	Small secreted protein
AW03_028050	COG0281	malic enzyme
AW03_028060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_028070	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AW03_028090	COG0510	thiamine kinase activity
AW03_028100	COG1523	belongs to the glycosyl hydrolase 13 family
AW03_028110	COG1597	lipid kinase activity
AW03_028130	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AW03_028140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW03_028150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW03_028160	COG2252	PERMEase
AW03_028170	COG4473	ABC transporter
AW03_028180	COG1131	(ABC) transporter
AW03_028190	COG1349	DNA-binding transcription factor activity
AW03_028200	COG1187	pseudouridine synthase activity
AW03_028210	COG2244	polysaccharide biosynthetic process
AW03_028220	COG2081	HI0933 family
AW03_028230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW03_028250	COG5578	integral membrane protein
AW03_028260	COG0673	inositol 2-dehydrogenase activity
AW03_028270	COG1653	transport
AW03_028280	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AW03_028290	COG4209	transmembrane transport
AW03_028300	COG2207	Transcriptional regulator
AW03_028310	COG1653	transport
AW03_028320	COG0395	ABC-type sugar transport system, permease component
AW03_028330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW03_028340	COG2124	cytochrome p450
AW03_028350	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AW03_028370	COG0156	8-amino-7-oxononanoate synthase activity
AW03_028380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW03_028400	COG1073	alpha beta
AW03_028450	COG1486	melibiose metabolic process
AW03_028460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW03_028470	COG0495	leucyl-tRNA aminoacylation
AW03_028490	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_028490	COG2202	Pas domain
AW03_028500	COG2814	Major facilitator Superfamily
AW03_028510	COG2433	Pfam Transposase IS66
AW03_028520	COG0577	efflux transmembrane transporter activity
AW03_028530	COG1136	(ABC) transporter
AW03_028540	COG2205	protein histidine kinase activity
AW03_028550	COG0745	RESPONSE REGULATOR receiver
AW03_028560	COG0577	efflux transmembrane transporter activity
AW03_028570	COG1136	(ABC) transporter
AW03_028600	COG1131	(ABC) transporter
AW03_028610	COG1725	Transcriptional regulator
AW03_028640	COG1242	4 iron, 4 sulfur cluster binding
AW03_028650	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AW03_028670	COG2267	carboxylic ester hydrolase activity
AW03_028680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AW03_028690	COG1113	amino acid transport
AW03_028700	COG0367	asparagine synthase
AW03_028710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AW03_028720	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AW03_028740	COG1506	peptidase
AW03_028750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW03_028760	COG1116	anion transmembrane transporter activity
AW03_028770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW03_028780	COG0494	nUDIX hydrolase
AW03_028790	COG4824	toxin secretion phage lysis holin
AW03_028800	COG0783	Belongs to the Dps family
AW03_028830	COG1854	S-ribosylhomocysteine lyase activity
AW03_028840	COG0288	reversible hydration of carbon dioxide
AW03_028850	COG0254	rRNA binding
AW03_028860	COG1271	oxidase subunit
AW03_028870	COG1294	oxidase, subunit
AW03_028890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW03_028900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW03_028900	COG1321	iron dependent repressor
AW03_028910	COG1121	(ABC) transporter
AW03_028920	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW03_028930	COG4948	Mandelate Racemase Muconate Lactonizing
AW03_028940	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_028950	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AW03_028960	COG0596	Alpha beta hydrolase
AW03_028970	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AW03_028980	COG1169	isochorismate synthase
AW03_028990	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW03_029000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW03_029010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW03_029020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW03_029030	COG0438	transferase activity, transferring glycosyl groups
AW03_029050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW03_029060	COG0438	transferase activity, transferring glycosyl groups
AW03_029070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW03_029080	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AW03_029090	COG0058	SHG alpha-glucan phosphorylase activity
AW03_029100	COG0297	glycogen (starch) synthase activity
AW03_029110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AW03_029120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AW03_029130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AW03_029150	COG3859	Proton-coupled thiamine transporter YuaJ
AW03_029160	COG1247	-acetyltransferase
AW03_029170	COG1247	-acetyltransferase
AW03_029180	COG2268	Band 7 protein
AW03_029190	COG1585	Membrane protein implicated in regulation of membrane protease activity
AW03_029200	COG2318	DinB family
AW03_029220	COG1454	alcohol dehydrogenase
AW03_029240	COG1510	regulation of RNA biosynthetic process
AW03_029260	COG0569	domain protein
AW03_029270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW03_029280	COG4682	membrane
AW03_029290	COG1705	Flagellar rod assembly protein muramidase FlgJ
AW03_029300	COG0477	Major facilitator Superfamily
AW03_029310	COG5553	Cysteine dioxygenase type I
AW03_029320	COG1968	undecaprenyl-diphosphatase activity
AW03_029330	COG0628	permease
AW03_029340	COG0673	inositol 2-dehydrogenase activity
AW03_029350	COG4806	L-rhamnose isomerase
AW03_029360	COG3254	rhamnose metabolic process
AW03_029370	COG1070	Carbohydrate kinase
AW03_029380	COG1349	DNA-binding transcription factor activity
AW03_029390	COG3347	Dehydrogenase
AW03_029390	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_029400	COG0840	transmembrane signaling receptor activity
AW03_029410	COG0840	transmembrane signaling receptor activity
AW03_029420	COG0840	transmembrane signaling receptor activity
AW03_029430	COG0840	transmembrane signaling receptor activity
AW03_029460	COG0432	Pfam Uncharacterised protein family UPF0047
AW03_029470	COG0366	Alpha amylase catalytic
AW03_029480	COG1253	flavin adenine dinucleotide binding
AW03_029490	COG2738	Putative neutral zinc metallopeptidase
AW03_029520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AW03_029550	COG0166	Belongs to the GPI family
AW03_029560	COG1979	alcohol dehydrogenase
AW03_029570	COG1979	alcohol dehydrogenase
AW03_029580	COG2155	Conserved Protein
AW03_029590	COG1098	S1 RNA binding domain
AW03_029600	COG0436	Aminotransferase
AW03_029610	COG1522	sequence-specific DNA binding
AW03_029620	COG2267	carboxylic ester hydrolase activity
AW03_029640	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AW03_029650	COG2205	protein histidine kinase activity
AW03_029670	COG5018	Exonuclease
AW03_029690	COG2814	Major facilitator Superfamily
AW03_029700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW03_029710	COG3011	Protein conserved in bacteria
AW03_029730	COG3290	protein histidine kinase activity
AW03_029740	COG4565	transcriptional regulatory protein
AW03_029790	COG3493	citrate carrier protein
AW03_029810	COG2111	Na H antiporter
AW03_029810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW03_029820	COG2111	Na H antiporter
AW03_029830	COG1006	Multisubunit Na H antiporter MnhC subunit
AW03_029840	COG0651	ATP synthesis coupled electron transport
AW03_029850	COG1863	multisubunit Na H antiporter MnhE subunit
AW03_029860	COG2212	antiporter activity
AW03_029870	COG1320	monovalent cation:proton antiporter activity
AW03_029880	COG2050	protein possibly involved in aromatic compounds catabolism
AW03_029890	COG2197	response regulator
AW03_029900	COG4585	Histidine kinase
AW03_029920	COG0142	geranyltranstransferase activity
AW03_029950	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AW03_029960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AW03_029970	COG1335	isochorismatase
AW03_029980	COG5506	Protein of unknown function (DUF1694)
AW03_030020	COG0628	permease
AW03_030050	COG1418	mRNA catabolic process
AW03_030060	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_030080	COG1511	domain protein
AW03_030090	COG1674	ftsk spoiiie
AW03_030090	COG0433	COG0433 Predicted ATPase
AW03_030100	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW03_030110	COG5417	Belongs to the EsaB family
AW03_030120	COG4842	Belongs to the WXG100 family
AW03_030130	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AW03_030130	COG2508	Transcriptional regulator
AW03_030140	COG0686	Belongs to the AlaDH PNT family
AW03_030150	COG5634	Uncharacterized conserved protein (DUF2278)
AW03_030160	COG3251	PFAM MbtH domain protein
AW03_030170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_030180	COG1535	isochorismatase
AW03_030180	COG3433	isochorismatase activity
AW03_030190	COG1021	2,3-dihydroxybenzoate-AMP ligase
AW03_030200	COG1169	isochorismate synthase
AW03_030210	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_030220	COG2819	hydrolase of the alpha beta superfamily
AW03_030230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AW03_030240	COG1268	BioY protein
AW03_030250	COG2056	Na+-H+ antiporter family
AW03_030260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AW03_030270	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AW03_030280	COG3584	3D domain protein
AW03_030300	COG1252	NADH dehydrogenase
AW03_030310	COG0492	ferredoxin-NADP+ reductase activity
AW03_030330	COG0516	GMP reductase activity
AW03_030340	COG2808	Putative FMN-binding domain
AW03_030350	COG0456	acetyltransferase
AW03_030360	COG0316	Belongs to the HesB IscA family
AW03_030370	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AW03_030380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW03_030390	COG4844	belongs to the
AW03_030400	COG1252	NADH dehydrogenase
AW03_030410	COG4837	Protein of unknown function (DUF1462)
AW03_030420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AW03_030430	COG4946	Tricorn protease homolog
AW03_030430	COG0823	Involved in the tonB-independent uptake of proteins
AW03_030430	COG1506	peptidase
AW03_030440	COG0083	homoserine kinase activity
AW03_030450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AW03_030460	COG0460	homoserine dehydrogenase
AW03_030470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW03_030480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW03_030490	COG0647	UMP catabolic process
AW03_030500	COG2445	Protein of unknown function DUF86
AW03_030510	COG4470	Protein conserved in bacteria
AW03_030530	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AW03_030540	COG0739	heme binding
AW03_030560	COG3377	Domain of unknown function (DUF1805)
AW03_030570	COG0737	Belongs to the 5'-nucleotidase family
AW03_030580	COG0730	response to heat
AW03_030590	COG1801	Protein of unknown function DUF72
AW03_030610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AW03_030620	COG2508	Transcriptional regulator
AW03_030630	COG2233	PERMEase
AW03_030640	COG2233	PERMEase
AW03_030650	COG3195	allantoin biosynthetic process
AW03_030650	COG3648	Uricase
AW03_030660	COG2351	hydroxyisourate hydrolase activity
AW03_030670	COG2080	2 iron, 2 sulfur cluster binding
AW03_030680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AW03_030690	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AW03_030700	COG2068	MobA-Related Protein
AW03_030710	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AW03_030730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AW03_030740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW03_030750	COG2356	endonuclease I
AW03_030760	COG3842	ATPase activity
AW03_030770	COG2188	Transcriptional regulator
AW03_030780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW03_030790	COG0395	ABC-type sugar transport system, permease component
AW03_030800	COG1175	transmembrane transport
AW03_030810	COG1653	transport
AW03_030820	COG2222	sugar isomerase
AW03_030830	COG0322	excinuclease ABC activity
AW03_030840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW03_030870	COG0346	lactoylglutathione lyase activity
AW03_030880	COG0719	Fe-S assembly protein
AW03_030890	COG0822	iron-sulfur transferase activity
AW03_030900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW03_030910	COG0719	Fe-S assembly protein
AW03_030920	COG0396	ATPase activity
AW03_030930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW03_030940	COG1464	Belongs to the NlpA lipoprotein family
AW03_030950	COG2011	ABC-type metal ion transport system permease component
AW03_030960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW03_030980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_030990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW03_031010	COG0509	glycine decarboxylation via glycine cleavage system
AW03_031020	COG1393	Belongs to the ArsC family
AW03_031030	COG1960	acyl-CoA dehydrogenase activity
AW03_031040	COG0183	Belongs to the thiolase family
AW03_031050	COG1024	Enoyl-CoA hydratase
AW03_031050	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW03_031070	COG0506	proline dehydrogenase activity
AW03_031090	COG5577	PFAM Coat F domain
AW03_031100	COG1846	Transcriptional regulator
AW03_031110	COG0477	Major facilitator Superfamily
AW03_031120	COG1942	4-Oxalocrotonate Tautomerase
AW03_031130	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_031140	COG0583	DNA-binding transcription factor activity
AW03_031160	COG1120	ATPase activity
AW03_031190	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_031200	COG0783	Belongs to the Dps family
AW03_031210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW03_031220	COG0745	RESPONSE REGULATOR receiver
AW03_031230	COG2205	protein histidine kinase activity
AW03_031230	COG2770	Histidine kinase
AW03_031240	COG1309	transcriptional regulator
AW03_031250	COG0114	fumarate hydratase activity
AW03_031270	COG0697	spore germination
AW03_031280	COG0814	amino acid
AW03_031300	COG2197	response regulator
AW03_031310	COG4585	Histidine kinase
AW03_031320	COG4758	membrane
AW03_031330	COG3595	metallopeptidase activity
AW03_031340	COG1842	Phage shock protein A
AW03_031350	COG4758	membrane
AW03_031360	COG2814	Major facilitator Superfamily
AW03_031370	COG2096	Adenosyltransferase
AW03_031380	COG1120	ATPase activity
AW03_031390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_031400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_031410	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_031420	COG3386	PFAM SMP-30 Gluconolaconase
AW03_031430	COG2205	protein histidine kinase activity
AW03_031440	COG0745	RESPONSE REGULATOR receiver
AW03_031460	COG1191	sigma factor activity
AW03_031480	COG2140	Oxalate decarboxylase
AW03_031500	COG0577	efflux transmembrane transporter activity
AW03_031510	COG1136	(ABC) transporter
AW03_031520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW03_031530	COG1120	ATPase activity
AW03_031540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_031550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_031560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_031570	COG0531	amino acid
AW03_031590	COG1988	membrane-bound metal-dependent
AW03_031600	COG1368	sulfuric ester hydrolase activity
AW03_031610	COG1910	domain protein
AW03_031620	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW03_031630	COG4149	molybdate abc transporter
AW03_031640	COG0656	L-ascorbic acid biosynthetic process
AW03_031660	COG0025	NhaP-type Na H and K H
AW03_031670	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW03_031680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AW03_031690	COG3973	AAA domain
AW03_031710	COG2860	membrane
AW03_031720	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AW03_031730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AW03_031740	COG2217	Heavy metal translocating P-type atpase
AW03_031750	COG2217	Heavy metal translocating P-type atpase
AW03_031760	COG2608	mercury ion transmembrane transporter activity
AW03_031770	COG1937	Protein conserved in bacteria
AW03_031780	COG0673	inositol 2-dehydrogenase activity
AW03_031790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW03_031800	COG1289	transmembrane transporter activity
AW03_031820	COG2076	Multidrug Resistance protein
AW03_031830	COG1309	transcriptional regulator
AW03_031840	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_031850	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AW03_031860	COG0557	exoribonuclease II activity
AW03_031870	COG1647	Serine aminopeptidase, S33
AW03_031880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW03_031890	COG0596	Alpha beta hydrolase
AW03_031900	COG1476	TRANSCRIPTIONal
AW03_031910	COG1396	sequence-specific DNA binding
AW03_031920	COG1396	sequence-specific DNA binding
AW03_031930	COG1733	regulation of RNA biosynthetic process
AW03_031980	COG1174	glycine betaine transport
AW03_031990	COG1732	Glycine betaine
AW03_032000	COG1174	glycine betaine transport
AW03_032010	COG0517	IMP dehydrogenase activity
AW03_032010	COG1125	glycine betaine transport
AW03_032020	COG1510	regulation of RNA biosynthetic process
AW03_032030	COG1174	glycine betaine transport
AW03_032040	COG1732	Glycine betaine
AW03_032050	COG1174	glycine betaine transport
AW03_032060	COG0517	IMP dehydrogenase activity
AW03_032060	COG1125	glycine betaine transport
AW03_032070	COG1510	regulation of RNA biosynthetic process
AW03_032080	COG2095	MarC family integral membrane protein
AW03_032100	COG3064	Membrane
AW03_032110	COG4640	response to antibiotic
AW03_032120	COG0456	acetyltransferase
AW03_032150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW03_032190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW03_032200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW03_032220	COG2234	aminopeptidase activity
AW03_032230	COG0148	phosphopyruvate hydratase activity
AW03_032240	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AW03_032250	COG0149	triose-phosphate isomerase activity
AW03_032260	COG0126	phosphoglycerate kinase activity
AW03_032270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW03_032280	COG2390	Transcriptional regulator
AW03_032290	COG2814	Major facilitator Superfamily
AW03_032300	COG1609	Transcriptional regulator
AW03_032310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_032320	COG0583	DNA-binding transcription factor activity
AW03_032330	COG0697	spore germination
AW03_032340	COG1113	amino acid transport
AW03_032350	COG3858	chitin binding
AW03_032360	COG1556	Lactate utilization protein
AW03_032370	COG1139	Iron-sulfur cluster binding protein
AW03_032380	COG0247	lactate metabolic process
AW03_032390	COG2197	response regulator
AW03_032400	COG4585	Histidine kinase
AW03_032410	COG0842	Transport permease protein
AW03_032420	COG1131	(ABC) transporter
AW03_032430	COG0596	Alpha beta hydrolase
AW03_032440	COG2208	phosphoserine phosphatase activity
AW03_032450	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AW03_032460	COG1874	Beta-galactosidase
AW03_032470	COG3833	ABC-type maltose transport systems, permease component
AW03_032480	COG1175	transmembrane transport
AW03_032490	COG2182	Extracellular solute-binding protein
AW03_032500	COG1609	Transcriptional regulator
AW03_032510	COG2186	Transcriptional regulator
AW03_032520	COG1620	l-lactate permease
AW03_032530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AW03_032550	COG5039	Polysaccharide pyruvyl transferase
AW03_032560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW03_032570	COG0110	maltose O-acetyltransferase activity
AW03_032580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AW03_032590	COG2244	polysaccharide biosynthetic process
AW03_032600	COG1216	Glycosyl transferase, family 2
AW03_032610	COG5039	Polysaccharide pyruvyl transferase
AW03_032620	COG1216	Glycosyl transferase, family 2
AW03_032640	COG0438	transferase activity, transferring glycosyl groups
AW03_032650	COG1215	transferase activity, transferring glycosyl groups
AW03_032660	COG0438	transferase activity, transferring glycosyl groups
AW03_032670	COG1086	Polysaccharide biosynthesis protein
AW03_032680	COG0489	protein tyrosine kinase activity
AW03_032690	COG3944	biosynthesis protein
AW03_032700	COG1396	sequence-specific DNA binding
AW03_032710	COG2272	Belongs to the type-B carboxylesterase lipase family
AW03_032730	COG3479	Phenolic acid decarboxylase
AW03_032750	COG1794	racemase activity, acting on amino acids and derivatives
AW03_032770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW03_032790	COG1621	beta-fructofuranosidase activity
AW03_032800	COG1621	beta-fructofuranosidase activity
AW03_032810	COG0531	amino acid
AW03_032820	COG1309	transcriptional regulator
AW03_032830	COG2076	Multidrug Resistance protein
AW03_032840	COG2076	Multidrug Resistance protein
AW03_032910	COG0740	serine-type endopeptidase activity
AW03_032920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW03_032930	COG0366	Alpha amylase catalytic
AW03_032940	COG1554	hydrolase, family 65, central catalytic
AW03_032950	COG5521	maltodextrose utilization protein MalA
AW03_032960	COG3833	ABC-type maltose transport systems, permease component
AW03_032970	COG1175	transmembrane transport
AW03_032980	COG2182	Extracellular solute-binding protein
AW03_032990	COG0366	Alpha amylase catalytic
AW03_033000	COG1609	Transcriptional regulator
AW03_033010	COG1611	Belongs to the LOG family
AW03_033020	COG1694	Mazg nucleotide pyrophosphohydrolase
AW03_033030	COG0659	secondary active sulfate transmembrane transporter activity
AW03_033040	COG0288	reversible hydration of carbon dioxide
AW03_033050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW03_033060	COG0577	efflux transmembrane transporter activity
AW03_033070	COG1136	(ABC) transporter
AW03_033080	COG5002	protein histidine kinase activity
AW03_033090	COG0745	RESPONSE REGULATOR receiver
AW03_033110	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AW03_033120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_033130	COG1481	regulation of sporulation
AW03_033140	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AW03_033150	COG1660	Displays ATPase and GTPase activities
AW03_033160	COG1051	belongs to the nudix hydrolase family
AW03_033170	COG0492	ferredoxin-NADP+ reductase activity
AW03_033180	COG3883	PFAM NLP P60 protein
AW03_033180	COG0791	NLP P60 protein
AW03_033190	COG0457	Tetratricopeptide repeat
AW03_033200	COG1132	(ABC) transporter
AW03_033250	COG0140	phosphoribosyl-ATP diphosphatase activity
AW03_033250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AW03_033260	COG0107	imidazoleglycerol-phosphate synthase activity
AW03_033270	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AW03_033280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AW03_033290	COG0131	Imidazoleglycerol-phosphate dehydratase
AW03_033300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AW03_033310	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AW03_033320	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AW03_033330	COG4990	cell redox homeostasis
AW03_033340	COG5297	Belongs to the glycosyl hydrolase family 6
AW03_033350	COG0110	maltose O-acetyltransferase activity
AW03_033360	COG0546	phosphoglycolate phosphatase activity
AW03_033370	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW03_033380	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AW03_033390	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AW03_033400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AW03_033410	COG0363	glucosamine-6-phosphate deaminase activity
AW03_033430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AW03_033440	COG1950	PFAM Membrane protein of
AW03_033450	COG1983	PspC domain protein
AW03_033460	COG3595	metallopeptidase activity
AW03_033490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW03_033500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW03_033510	COG0556	nucleotide-excision repair
AW03_033520	COG4897	Protein conserved in bacteria
AW03_033530	COG3848	Pyruvate phosphate dikinase
AW03_033530	COG0574	Belongs to the PEP-utilizing enzyme family
AW03_033540	COG1309	transcriptional regulator
AW03_033550	COG2814	Major facilitator Superfamily
AW03_033560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW03_033580	COG3409	Peptidoglycan-binding domain 1 protein
AW03_033580	COG0793	Belongs to the peptidase S41A family
AW03_033590	COG2177	Part of the ABC transporter FtsEX involved in
AW03_033600	COG2884	Cell division ATP-binding protein ftsE
AW03_033610	COG2010	Cytochrome c
AW03_033620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_033630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AW03_033640	COG0653	protein targeting
AW03_033650	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AW03_033680	COG1516	flagellar protein fliS
AW03_033690	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AW03_033700	COG1334	flagellar protein FlaG
AW03_033710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW03_033720	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AW03_033730	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AW03_033750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW03_033760	COG1256	bacterial-type flagellum assembly
AW03_033760	COG4786	Flagellar basal body rod
AW03_033770	COG3418	PFAM FlgN family protein
AW03_033780	COG2747	anti-sigma28 factor FlgM
AW03_033800	COG1040	competence protein
AW03_033820	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AW03_033830	COG1307	EDD domain protein, DegV family
AW03_033840	COG2197	response regulator
AW03_033850	COG4585	Histidine kinase
AW03_033860	COG1739	Uncharacterized protein family UPF0029
AW03_033870	COG1316	TRANSCRIPTIONal
AW03_033880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW03_033890	COG0438	transferase activity, transferring glycosyl groups
AW03_033900	COG1215	transferase activity, transferring glycosyl groups
AW03_033910	COG3206	protein involved in exopolysaccharide biosynthesis
AW03_033920	COG3307	-O-antigen
AW03_033930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW03_033940	COG0438	transferase activity, transferring glycosyl groups
AW03_033940	COG0297	glycogen (starch) synthase activity
AW03_033950	COG2244	polysaccharide biosynthetic process
AW03_033980	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_033980	COG2247	cell wall binding repeat
AW03_033990	COG2385	sporulation resulting in formation of a cellular spore
AW03_033990	COG2247	cell wall binding repeat
AW03_034010	COG1316	TRANSCRIPTIONal
AW03_034020	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW03_034060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW03_034070	COG1134	teichoic acid transport
AW03_034080	COG1682	transport, permease protein
AW03_034120	COG0463	Glycosyl transferase, family 2
AW03_034210	COG4193	domain, Protein
AW03_034220	COG1482	cell wall glycoprotein biosynthetic process
AW03_034230	COG0697	spore germination
AW03_034240	COG0814	amino acid
AW03_034260	COG2814	Major facilitator Superfamily
AW03_034270	COG1316	TRANSCRIPTIONal
AW03_034280	COG0561	phosphatase activity
AW03_034290	COG0791	NLP P60 protein
AW03_034310	COG2843	Capsule synthesis protein
AW03_034330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AW03_034340	COG1609	Transcriptional regulator
AW03_034350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW03_034360	COG1869	D-ribose catabolic process
AW03_034370	COG1129	ABC transporter
AW03_034380	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW03_034390	COG1879	ABC-type sugar transport system periplasmic component
AW03_034400	COG3103	Sh3 type 3 domain protein
AW03_034430	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW03_034440	COG3527	Alpha-acetolactate decarboxylase
AW03_034450	COG0028	Belongs to the TPP enzyme family
AW03_034460	COG0583	DNA-binding transcription factor activity
AW03_034470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW03_034500	COG5337	Spore coat protein CotH
AW03_034520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AW03_034540	COG0405	Gamma-glutamyltransferase
AW03_034550	COG1522	sequence-specific DNA binding
AW03_034560	COG2059	Chromate
AW03_034570	COG2059	Chromate
AW03_034600	COG5444	nuclease activity
AW03_034630	COG5444	nuclease activity
AW03_034660	COG3878	Protein conserved in bacteria
AW03_034670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW03_034680	COG4464	protein tyrosine phosphatase activity
AW03_034690	COG0489	protein tyrosine kinase activity
AW03_034700	COG3944	biosynthesis protein
AW03_034720	COG4715	Zinc finger, swim domain protein
AW03_034730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW03_034740	COG0561	phosphatase activity
AW03_034750	COG1349	DNA-binding transcription factor activity
AW03_034760	COG0629	single-stranded DNA binding
AW03_034790	COG3764	Sortase (surface protein transpeptidase)
AW03_034810	COG3279	Response regulator of the LytR AlgR family
AW03_034820	COG2972	Histidine kinase
AW03_034820	COG0745	RESPONSE REGULATOR receiver
AW03_034830	COG1970	mechanosensitive ion channel activity
AW03_034840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW03_034850	COG0457	Tetratricopeptide repeat
AW03_034860	COG4786	Flagellar basal body rod
AW03_034870	COG4786	Flagellar basal body rod
AW03_034880	COG1077	Cell shape determining protein MreB Mrl
AW03_034890	COG1609	Transcriptional regulator
AW03_034900	COG1846	Transcriptional regulator
AW03_034910	COG2814	Major facilitator Superfamily
AW03_034920	COG3420	alginic acid biosynthetic process
AW03_034930	COG1953	Uracil, thiamine, allantoin
AW03_034940	COG0477	Major facilitator Superfamily
AW03_034950	COG1335	isochorismatase
AW03_034970	COG0004	ammonium transporteR
AW03_034980	COG0347	Belongs to the P(II) protein family
AW03_034990	COG0671	phosphoesterase, PA-phosphatase related
AW03_035010	COG0739	heme binding
AW03_035020	COG1247	-acetyltransferase
AW03_035040	COG2089	acid synthase
AW03_035060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW03_035070	COG0789	Transcriptional regulator
AW03_035090	COG2910	NAD(P)H-binding
AW03_035100	COG1959	2 iron, 2 sulfur cluster binding
AW03_035110	COG0804	urea catabolic process
AW03_035120	COG0832	Belongs to the urease beta subunit family
AW03_035130	COG0831	urea catabolic process
AW03_035150	COG3237	CsbD-like
AW03_035160	COG1994	Peptidase M50
AW03_035170	COG0457	Tetratricopeptide repeat
AW03_035180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AW03_035190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW03_035210	COG2304	oxidoreductase activity
AW03_035220	COG2304	oxidoreductase activity
AW03_035230	COG2385	sporulation resulting in formation of a cellular spore
AW03_035240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AW03_035260	COG4836	Membrane
AW03_035280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AW03_035290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AW03_035300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AW03_035310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AW03_035320	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AW03_035330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AW03_035340	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AW03_035350	COG0356	it plays a direct role in the translocation of protons across the membrane
AW03_035370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AW03_035380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AW03_035390	COG4475	Protein of unknown function (DUF436)
AW03_035400	COG0698	ribose 5-phosphate isomerase
AW03_035410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW03_035420	COG1971	Probably functions as a manganese efflux pump
AW03_035430	COG0009	L-threonylcarbamoyladenylate synthase
AW03_035440	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AW03_035480	COG2890	protein-(glutamine-N5) methyltransferase activity
AW03_035490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AW03_035500	COG0346	lactoylglutathione lyase activity
AW03_035510	COG0789	Transcriptional regulator
AW03_035520	COG0679	Auxin Efflux Carrier
AW03_035530	COG0281	malic enzyme
AW03_035540	COG1435	thymidine kinase activity
AW03_035550	COG0254	rRNA binding
AW03_035560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AW03_035570	COG1494	fructose-1,6-bisphosphatase
AW03_035580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AW03_035590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AW03_035600	COG0191	fructose-bisphosphate aldolase activity
AW03_035610	COG2204	response regulator
AW03_035620	COG4821	SIS domain
AW03_035630	COG0504	CTP synthase activity
AW03_035640	COG3343	RNA polymerase activity
AW03_035650	COG1960	acyl-CoA dehydrogenase activity
AW03_035660	COG0247	lactate metabolic process
AW03_035660	COG2181	nitrate reductase activity
AW03_035670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW03_035680	COG4294	response to UV
AW03_035700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW03_035710	COG1132	(ABC) transporter
AW03_035720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW03_035730	COG2181	nitrate reductase activity
AW03_035740	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AW03_035750	COG1140	nitrate reductase beta subunit
AW03_035760	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AW03_035770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW03_035790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW03_035800	COG2223	nitrite transmembrane transporter activity
AW03_035810	COG0018	arginyl-trna synthetase
AW03_035820	COG4506	Protein conserved in bacteria
AW03_035840	COG0535	radical SAM domain protein
AW03_035860	COG1131	(ABC) transporter
AW03_035870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW03_035880	COG0612	Peptidase, M16
AW03_035890	COG0612	Peptidase, M16
AW03_035910	COG3391	amine dehydrogenase activity
AW03_035920	COG3391	amine dehydrogenase activity
AW03_035930	COG0457	Tetratricopeptide repeat
AW03_035990	COG1131	(ABC) transporter
AW03_036010	COG0010	Belongs to the arginase family
AW03_036020	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AW03_036030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW03_036050	COG1994	Peptidase M50
AW03_036060	COG1942	4-Oxalocrotonate Tautomerase
AW03_036070	COG1846	Transcriptional regulator
AW03_036080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW03_036100	COG0477	Major facilitator Superfamily
AW03_036110	COG1959	2 iron, 2 sulfur cluster binding
AW03_036120	COG3465	dGTPase activity
AW03_036130	COG1078	dGTPase activity
AW03_036140	COG4844	belongs to the
AW03_036160	COG0697	spore germination
AW03_036170	COG0095	Lipoate-protein ligase
AW03_036180	COG0583	DNA-binding transcription factor activity
AW03_036190	COG0280	phosphate acetyltransferase
AW03_036210	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_036220	COG0436	Aminotransferase
AW03_036230	COG2814	Major facilitator Superfamily
AW03_036240	COG0151	Belongs to the GarS family
AW03_036250	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_036260	COG1917	Cupin 2, conserved barrel domain protein
AW03_036270	COG0077	Prephenate dehydratase
AW03_036280	COG2814	Major facilitator Superfamily
AW03_036290	COG0833	amino acid
AW03_036300	COG4187	Peptidase family M20/M25/M40
AW03_036310	COG1012	belongs to the aldehyde dehydrogenase family
AW03_036320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW03_036340	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AW03_036350	COG1091	dTDP-4-dehydrorhamnose reductase activity
AW03_036360	COG1088	dTDP-glucose 4,6-dehydratase activity
AW03_036370	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AW03_036380	COG3980	spore coat polysaccharide biosynthesis protein
AW03_036390	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AW03_036400	COG2089	acid synthase
AW03_036410	COG0456	acetyltransferase
AW03_036420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW03_036430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AW03_036440	COG0463	Glycosyl transferase, family 2
AW03_036460	COG2363	Small membrane protein
AW03_036470	COG2233	PERMEase
AW03_036490	COG1012	belongs to the aldehyde dehydrogenase family
AW03_036500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AW03_036510	COG1216	Glycosyl transferase, family 2
AW03_036520	COG0351	phosphomethylpyrimidine kinase
AW03_036540	COG1621	beta-fructofuranosidase activity
AW03_036550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_036550	COG1263	PTS System
AW03_036560	COG2116	formate transmembrane transporter activity
AW03_036570	COG3711	transcriptional antiterminator
AW03_036590	COG1404	Belongs to the peptidase S8 family
AW03_036600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_036610	COG0778	Nitroreductase
AW03_036620	COG0772	Belongs to the SEDS family
AW03_036640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AW03_036650	COG1845	cytochrome c oxidase, subunit III
AW03_036660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW03_036670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW03_036680	COG2261	transglycosylase associated protein
AW03_036690	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AW03_036700	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AW03_036710	COG2246	polysaccharide biosynthetic process
AW03_036720	COG1309	transcriptional regulator
AW03_036740	COG3162	membrane
AW03_036750	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW03_036760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AW03_036770	COG2837	iron assimilation
AW03_036780	COG2822	iron ion transport
AW03_036790	COG0672	)-iron permease
AW03_036800	COG0352	thiamine-phosphate diphosphorylase activity
AW03_036810	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AW03_036820	COG0583	DNA-binding transcription factor activity
AW03_036830	COG1380	Effector of murein hydrolase LrgA
AW03_036840	COG1346	cytolysis
AW03_036850	COG2814	Major facilitator Superfamily
AW03_036860	COG4895	conserved protein (DUF2196)
AW03_036870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AW03_036880	COG0346	lactoylglutathione lyase activity
AW03_036910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW03_036920	COG1404	Belongs to the peptidase S8 family
AW03_036930	COG1263	PTS System
AW03_036930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_036940	COG3711	transcriptional antiterminator
AW03_036950	COG1442	glycosyl transferase family 8
AW03_036960	COG5522	Integral membrane protein (intg_mem_TP0381)
AW03_036970	COG1846	Transcriptional regulator
AW03_036980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AW03_036990	COG2234	aminopeptidase activity
AW03_037000	COG2357	RelA SpoT domain protein
AW03_037010	COG1575	Belongs to the MenA family. Type 1 subfamily
AW03_037030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_037040	COG1696	Membrane protein involved in D-alanine export
AW03_037050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_037060	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW03_037070	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AW03_037080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW03_037090	COG1486	melibiose metabolic process
AW03_037100	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW03_037110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW03_037120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW03_037130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_037130	COG3711	transcriptional antiterminator
AW03_037150	COG2094	Belongs to the DNA glycosylase MPG family
AW03_037160	COG0753	catalase activity
AW03_037170	COG2814	Major facilitator Superfamily
AW03_037180	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW03_037190	COG1131	(ABC) transporter
AW03_037230	COG1595	DNA-templated transcription, initiation
AW03_037240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AW03_037250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AW03_037260	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AW03_037270	COG4988	ABC transporter
AW03_037280	COG1294	oxidase, subunit
AW03_037290	COG1271	oxidase subunit
AW03_037300	COG3493	citrate carrier protein
AW03_037310	COG0501	Belongs to the peptidase M48B family
AW03_037330	COG0726	polysaccharide deacetylase
AW03_037340	COG3842	ATPase activity
AW03_037350	COG2508	Transcriptional regulator
AW03_037360	COG1012	belongs to the aldehyde dehydrogenase family
AW03_037370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_037390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW03_037400	COG1881	PFAM PEBP family protein
AW03_037410	COG0583	DNA-binding transcription factor activity
AW03_037430	COG4585	Histidine kinase
AW03_037440	COG2197	response regulator
AW03_037450	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW03_037480	COG4894	glucomannan catabolic process
AW03_037490	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AW03_037500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AW03_037510	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_037520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AW03_037530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AW03_037540	COG2610	gluconate transmembrane transporter activity
AW03_037550	COG0500	methyltransferase
AW03_037560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW03_037590	COG0753	catalase activity
AW03_037590	COG0693	protein deglycase activity
AW03_037600	COG2851	Citrate transporter
AW03_037610	COG2273	Hydrolase Family 16
AW03_037620	COG3711	transcriptional antiterminator
AW03_037640	COG2270	Major facilitator Superfamily
AW03_037650	COG0513	Belongs to the DEAD box helicase family
AW03_037660	COG2755	lipolytic protein G-D-S-L family
AW03_037660	COG3401	FG-GAP repeat protein
AW03_037700	COG0697	spore germination
AW03_037710	COG0589	response to stress
AW03_037720	COG2723	6-phospho-beta-galactosidase activity
AW03_037730	COG2190	(PTS) system
AW03_037730	COG1263	PTS System
AW03_037730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_037810	COG5444	nuclease activity
AW03_037860	COG0494	nUDIX hydrolase
AW03_037870	COG3507	Belongs to the glycosyl hydrolase 43 family
AW03_037890	COG2986	histidine ammonia-lyase
AW03_037900	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AW03_037910	COG1228	amidohydrolase
AW03_037920	COG0010	Belongs to the arginase family
AW03_037930	COG0833	amino acid
AW03_037940	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AW03_037950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW03_037960	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AW03_037970	COG2390	Transcriptional regulator
AW03_037990	COG3192	ethanolamine utilization protein
AW03_038000	COG2079	MmgE PrpD family protein
AW03_038020	COG1126	abc transporter atp-binding protein
AW03_038030	COG0765	amino acid transport
AW03_038040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_038070	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AW03_038080	COG0561	phosphatase activity
AW03_038140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_038150	COG5294	Protein conserved in bacteria
AW03_038160	COG0577	efflux transmembrane transporter activity
AW03_038170	COG1136	(ABC) transporter
AW03_038180	COG2205	protein histidine kinase activity
AW03_038190	COG0745	RESPONSE REGULATOR receiver
AW03_038200	COG0191	fructose-bisphosphate aldolase activity
AW03_038210	COG1082	Xylose isomerase domain protein TIM barrel
AW03_038220	COG1082	Xylose isomerase domain protein TIM barrel
AW03_038230	COG0673	inositol 2-dehydrogenase activity
AW03_038240	COG2814	Major facilitator Superfamily
AW03_038250	COG1082	Xylose isomerase domain protein TIM barrel
AW03_038260	COG3962	Belongs to the TPP enzyme family
AW03_038270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW03_038290	COG1012	belongs to the aldehyde dehydrogenase family
AW03_038300	COG1349	DNA-binding transcription factor activity
AW03_038310	COG0667	Aldo Keto reductase
AW03_038340	COG2814	Major facilitator Superfamily
AW03_038350	COG0326	Molecular chaperone. Has ATPase activity
AW03_038370	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_038380	COG1309	transcriptional regulator
AW03_038390	COG1012	belongs to the aldehyde dehydrogenase family
AW03_038400	COG1714	RDD family
AW03_038410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AW03_038430	COG1714	RDD family
AW03_038440	COG2311	Membrane
AW03_038450	COG1917	Cupin 2, conserved barrel domain protein
AW03_038460	COG1309	transcriptional regulator
AW03_038470	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_038480	COG1846	Transcriptional regulator
AW03_038490	COG1380	Effector of murein hydrolase LrgA
AW03_038500	COG1346	cytolysis
AW03_038510	COG5039	Polysaccharide pyruvyl transferase
AW03_038520	COG1929	Belongs to the glycerate kinase type-1 family
AW03_038530	COG1802	Transcriptional regulator
AW03_038540	COG1070	Carbohydrate kinase
AW03_038550	COG2610	gluconate transmembrane transporter activity
AW03_038560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AW03_038570	COG0450	alkyl hydroperoxide reductase
AW03_038580	COG3634	alkyl hydroperoxide reductase activity
AW03_038600	COG2723	6-phospho-beta-galactosidase activity
AW03_038610	COG2190	(PTS) system
AW03_038620	COG2188	Transcriptional regulator
AW03_038650	COG1131	(ABC) transporter
AW03_038660	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AW03_038680	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AW03_038710	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AW03_038740	COG1063	alcohol dehydrogenase
AW03_038780	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AW03_038790	COG0456	acetyltransferase
AW03_038800	COG0457	Tetratricopeptide repeat
AW03_038820	COG0010	Belongs to the arginase family
AW03_038830	COG0833	amino acid
AW03_038840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW03_038850	COG3829	transcription factor binding
AW03_038860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW03_038870	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AW03_038880	COG4853	Protein conserved in bacteria
AW03_038890	COG4863	YycH protein
AW03_038900	COG5002	protein histidine kinase activity
AW03_038910	COG0745	RESPONSE REGULATOR receiver
AW03_038930	COG0346	lactoylglutathione lyase activity
AW03_038940	COG0305	Participates in initiation and elongation during chromosome replication
AW03_038970	COG3093	addiction module antidote protein HigA
AW03_038980	COG2807	transmembrane transport
AW03_038990	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AW03_039000	COG0359	binds to the 23S rRNA
AW03_039010	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AW03_039020	COG4241	membrane
AW03_039040	COG5577	PFAM Coat F domain
AW03_039050	COG1733	regulation of RNA biosynthetic process
AW03_039060	COG1227	inorganic diphosphatase activity
AW03_039090	COG2271	Major facilitator Superfamily
AW03_039100	COG0789	Transcriptional regulator
AW03_039100	COG4978	Transcriptional regulator
AW03_039120	COG4319	ketosteroid isomerase
AW03_039130	COG1357	PFAM Pentapeptide repeats (8 copies)
AW03_039140	COG2814	Major facilitator Superfamily
AW03_039150	COG0583	DNA-binding transcription factor activity
AW03_039160	COG2153	protein acetylation
AW03_039180	COG0583	DNA-binding transcription factor activity
AW03_039210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_039220	COG1846	Transcriptional regulator
AW03_039230	COG2153	protein acetylation
AW03_039240	COG2364	Membrane
AW03_039250	COG0456	acetyltransferase
AW03_039260	COG2315	Protein conserved in bacteria
AW03_039270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW03_039300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW03_039310	COG0798	PFAM Bile acid sodium symporter
AW03_039320	COG0346	lactoylglutathione lyase activity
AW03_039330	COG0640	Transcriptional regulator
AW03_039350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW03_039360	COG1331	Highly conserved protein containing a thioredoxin domain
AW03_039370	COG0863	Belongs to the N(4) N(6)-methyltransferase family
AW03_039390	COG1331	Highly conserved protein containing a thioredoxin domain
AW03_039400	COG1266	CAAX protease self-immunity
AW03_039410	COG0477	Major facilitator Superfamily
AW03_039410	COG2814	Major facilitator Superfamily
AW03_039420	COG0110	maltose O-acetyltransferase activity
AW03_039430	COG0346	lactoylglutathione lyase activity
AW03_039440	COG1609	Transcriptional regulator
AW03_039450	COG0708	Exodeoxyribonuclease III
AW03_039460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AW03_039470	COG0629	single-stranded DNA binding
AW03_039480	COG0360	Binds together with S18 to 16S ribosomal RNA
AW03_039490	COG0012	GTP binding
AW03_039500	COG0243	molybdopterin cofactor binding
AW03_039510	COG4481	Protein conserved in bacteria
AW03_039520	COG3949	Membrane
AW03_039540	COG1475	DNA binding
AW03_039550	COG1192	Involved in chromosome partitioning
AW03_039570	COG1475	DNA binding
AW03_039580	COG0357	Ribosomal RNA small subunit methyltransferase G
AW03_039590	COG0445	tRNA wobble uridine modification
AW03_039600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AW03_039610	COG1847	R3H domain protein
AW03_039620	COG0706	membrane insertase activity
AW03_039630	COG0594	ribonuclease P activity