locus-tag	class	description
A4A60_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A4A60_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A4A60_00015	ENOG410848D	S4 domain protein YaaA
A4A60_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4A60_00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4A60_00070	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A4A60_00080	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A4A60_00085	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A4A60_00090	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A4A60_00100	ENOG4105ZMH	deoxynucleoside kinase
A4A60_00110	ENOG4105VRS	hydrolase family 18
A4A60_00115	ENOG4105GTG	Isochorismatase
A4A60_00120	ENOG4108Z6B	deaminase
A4A60_00130	ENOG4105C6E	dna polymerase iii
A4A60_00135	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A4A60_00140	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A4A60_00150	ENOG41067KS	pro-sigma K processing
A4A60_00190	ENOG4105CDW	Resistance protein
A4A60_00195	ENOG4105CXN	decarboxylase
A4A60_00200	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A4A60_00205	ENOG4105X0R	protein from nitrogen regulatory protein P-II
A4A60_00210	ENOG4105XVJ	Protein of unknown function (DUF327)
A4A60_00215	ENOG4105FA2	dna polymerase iii
A4A60_00220	ENOG4105MA4	psp1 domain protein
A4A60_00225	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
A4A60_00230	ENOG41060K3	Methyltransferase
A4A60_00235	ENOG4105VC4	domain protein
A4A60_00240	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A4A60_00250	ENOG4105KRN	Transcriptional regulator, abrb family
A4A60_00255	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A4A60_00260	ENOG4105F8V	Hydrolase, tatD family
A4A60_00265	ENOG41069ER	domain protein
A4A60_00275	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A4A60_00280	ENOG4105XFA	sporulation peptidase YabG
A4A60_00285	ENOG4105W42	Veg protein
A4A60_00290	ENOG4105XEW	small acid-soluble spore protein
A4A60_00295	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A4A60_00300	ENOG4105DFT	pur operon repressor
A4A60_00305	ENOG4105KME	endoribonuclease L-psp
A4A60_00310	ENOG4105K4W	Could be involved in septation (By similarity)
A4A60_00320	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A4A60_00325	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A4A60_00330	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A4A60_00335	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A4A60_00345	ENOG4108JA2	transcriptioN-repair coupling factor
A4A60_00350	ENOG4108M14	stage v sporulation protein t
A4A60_00360	ENOG4108IY2	MazG family
A4A60_00365	ENOG41082I2	s4 domain protein
A4A60_00370	ENOG4105VYY	sporulation protein yabp
A4A60_00385	ENOG41060GV	RNA binding s1 domain protein
A4A60_00415	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A4A60_00420	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A4A60_00425	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A4A60_00435	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A4A60_00440	ENOG4107U48	ppic-type peptidyL-prolyl cis-trans isomerase
A4A60_00445	ENOG4105C6T	cysteine synthase
A4A60_00450	ENOG4105CRQ	synthase (Component I)
A4A60_00455	ENOG4105DDQ	anthranilate synthase
A4A60_00460	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
A4A60_00465	ENOG4105EEI	dihydropteroate synthase
A4A60_00470	ENOG4105KRF	dihydroneopterin aldolase
A4A60_00475	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A4A60_00485	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A4A60_00490	ENOG4105CRK	lysyL-tRNA synthetase
A4A60_00575	ENOG4108Z0C	Uvrb UvrC protein
A4A60_00580	ENOG41066A3	ATP guanido phosphotransferase
A4A60_00590	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A4A60_00595	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
A4A60_00600	ENOG4105CTP	PilT protein domain protein
A4A60_00605	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
A4A60_00610	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A4A60_00615	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A4A60_00625	ENOG4105D7W	serine acetyltransferase
A4A60_00630	ENOG4105C8N	cysteinyl-tRNA synthetase
A4A60_00635	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A4A60_00640	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A4A60_00645	ENOG4105M0M	Tetracycline resistance protein
A4A60_00665	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A4A60_00670	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A4A60_00680	ENOG4108VZM	50s ribosomal protein L10
A4A60_00685	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A4A60_00690	ENOG4107Y49	methyltransferase
A4A60_00695	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4A60_00700	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4A60_00705	ENOG4105XPM	ribosomal protein
A4A60_00710	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A4A60_00715	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A4A60_00720	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A4A60_00725	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A4A60_00730	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
A4A60_00735	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A4A60_00740	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A4A60_00745	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A4A60_00750	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A4A60_00755	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A4A60_00760	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A4A60_00765	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A4A60_00770	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A4A60_00775	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A4A60_00780	ENOG41082SA	50s ribosomal protein l29
A4A60_00785	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A4A60_00790	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A4A60_00800	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A4A60_00810	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A4A60_00815	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A4A60_00820	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A4A60_00825	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A4A60_00830	ENOG4105VPB	50S ribosomal protein L30
A4A60_00835	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A4A60_00840	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A4A60_00850	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A4A60_00860	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A4A60_00870	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A4A60_00875	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A4A60_00880	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4A60_00885	ENOG4108ZT0	50S ribosomal protein l17
A4A60_00890	ENOG4108JJB	ABC transporter
A4A60_00895	ENOG4108JJB	ABC transporter
A4A60_00900	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
A4A60_00905	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A4A60_00910	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A4A60_00915	ENOG4108UJD	30S ribosomal protein S9
A4A60_00920	ENOG4108I0C	methyltransferase
A4A60_00935	ENOG4105D1F	ATP-binding protein
A4A60_00950	ENOG4108NMV	polysaccharide deacetylase
A4A60_01035	ENOG4105CHH	sulfate transporter
A4A60_01045	ENOG4108SA1	esterase
A4A60_01065	ENOG410874W	AraC family transcriptional regulator
A4A60_01075	ENOG4105D17	glycoside hydrolase, family 3 domain protein
A4A60_01095	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A4A60_01105	ENOG4105EWC	Purine nucleoside phosphorylase
A4A60_01135	ENOG4105EMN	RNA polymerase sigma factor
A4A60_01145	ENOG4105C8B	TIGR00159 family
A4A60_01150	ENOG4107U5W	ybbr family
A4A60_01155	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A4A60_01160	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A4A60_01185	ENOG4108151	Beta-lactamase domain protein
A4A60_01190	ENOG4108TWJ	NADH dehydrogenase subunit 5
A4A60_01210	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
A4A60_01230	ENOG4105G0J	serine threonine protein kinase
A4A60_01240	ENOG4106K80	
A4A60_01255	ENOG4106DDH	Sporulation-specific SASP protein
A4A60_01265	ENOG4108HWY	Beta-lactamase
A4A60_01270	ENOG4107E6A	Cytochrome p-450
A4A60_01280	ENOG4107QTZ	amino acid
A4A60_01285	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
A4A60_01290	ENOG4105CXY	transporter
A4A60_01300	ENOG410645S	MarR family Transcriptional regulator
A4A60_01330	ENOG4106AXJ	AraC family transcriptional regulator
A4A60_01345	ENOG4105NVB	glycoside hydrolase, family 19
A4A60_01350	ENOG4105GIG	
A4A60_01355	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A4A60_01360	ENOG4108TCS	Glutamyl endopeptidase
A4A60_01370	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
A4A60_01375	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
A4A60_01380	ENOG4107ZTW	SNARE associated Golgi
A4A60_01405	ENOG4105C72	UPF0176 protein
A4A60_01420	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
A4A60_01425	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A4A60_01430	ENOG4108X79	transcriptional regulator
A4A60_01440	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A4A60_01445	ENOG4108IQI	permease
A4A60_01450	ENOG4108J5H	Homocysteine s-methyltransferase
A4A60_01465	ENOG4105CSV	Glutaminase
A4A60_01480	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
A4A60_01485	ENOG4105C26	Dehydrogenase
A4A60_01490	ENOG4105DJB	Major Facilitator Superfamily
A4A60_01495	ENOG4105EQX	glucarate dehydratase
A4A60_01500	ENOG41073TP	transcriptional regulator
A4A60_01505	ENOG4105CTX	dehydratase
A4A60_01520	ENOG4106UX7	integral membrane protein
A4A60_01525	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A4A60_01570	ENOG4105DGI	Alkaline phosphatase
A4A60_01575	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A4A60_01580	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A4A60_01585	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A4A60_01590	ENOG4107EPV	Aminotransferase class V
A4A60_01595	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A4A60_01600	ENOG4105J7D	transcriptional regulator
A4A60_01605	ENOG4107RB3	L-asparaginase
A4A60_01610	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
A4A60_01620	ENOG41060AI	SEC-C motif
A4A60_01630	ENOG4107Y7X	LytTR
A4A60_01635	ENOG4108IUW	ABC transporter
A4A60_01640	ENOG4108SDH	ABC, transporter
A4A60_01675	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A4A60_01685	ENOG4105DSE	periplasmic solute binding protein
A4A60_01690	ENOG4105DIK	(ABC) transporter
A4A60_01710	ENOG4108N0M	stress protein
A4A60_01715	ENOG4106FN3	tellurium resistance protein
A4A60_01720	ENOG4106FN3	tellurium resistance protein
A4A60_01725	ENOG4107TS3	membrane protein, TerC
A4A60_01730	ENOG4108TTB	tellurium resistance protein
A4A60_01740	ENOG41079KZ	Major Facilitator Superfamily
A4A60_01745	ENOG4107XZQ	multidrug resistance protein
A4A60_01790	ENOG4108A65	Transcriptional regulator
A4A60_01795	ENOG4108IJ7	Glycine betaine
A4A60_01800	ENOG4107SQ8	Glycine betaine
A4A60_01835	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A4A60_01855	ENOG4105EIG	urea carboxylase-associated protein 1
A4A60_01860	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
A4A60_01865	ENOG4105I1F	Resistance protein
A4A60_01870	ENOG4107Z3Y	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A4A60_01875	ENOG41089UC	methyltransferase, type 11
A4A60_01880	ENOG4105C5Q	Transcriptional regulator
A4A60_01885	ENOG4105I82	acetyl xylan esterase
A4A60_01890	ENOG410756H	nucleotidyltransferase
A4A60_01900	ENOG4105C26	Dehydrogenase
A4A60_01905	ENOG4105CK7	Sodium proline symporter
A4A60_01910	ENOG4107YHD	transcriptional regulator
A4A60_01920	ENOG4108PJD	permease
A4A60_01925	ENOG4105U6C	Alpha beta hydrolase fold protein
A4A60_01935	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A4A60_01940	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
A4A60_01945	ENOG4108IFG	nitrite reductase, (NAD(P)H)
A4A60_01950	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A4A60_01970	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
A4A60_01985	ENOG4105E5Q	amino acid AbC transporter
A4A60_01990	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
A4A60_02000	ENOG4105HHM	rdd domain containing protein
A4A60_02010	ENOG4105K56	Transcriptional regulator
A4A60_02025	ENOG4105CS2	ec 3.2.1.21
A4A60_02045	ENOG41080HJ	6-phospho 3-hexuloisomerase
A4A60_02050	ENOG4108VA3	3-hexulose-6-phosphate synthase
A4A60_02055	ENOG4105KVH	Transcriptional regulator
A4A60_02070	ENOG4105CEY	Amp-dependent synthetase and ligase
A4A60_02100	ENOG4105SX7	Transporter
A4A60_02110	ENOG4105W8Z	4'-phosphopantetheinyl transferase
A4A60_02120	ENOG4105CDA	abc transporter atp-binding protein
A4A60_02125	ENOG4105DRP	amino acid AbC transporter
A4A60_02135	ENOG4106P55	Transcriptional regulator
A4A60_02140	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A4A60_02145	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A4A60_02150	ENOG41069ZX	
A4A60_02165	ENOG4105DUX	Transporter
A4A60_02185	ENOG4105E1K	spore germination protein
A4A60_02205	ENOG4107WD8	ABC transporter, permease
A4A60_02210	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4A60_02215	ENOG4105BZU	Histidine kinase
A4A60_02235	ENOG4105CFH	Aspartokinase
A4A60_02240	ENOG4105DHS	permease protein
A4A60_02245	ENOG4105CM4	permease protein
A4A60_02250	ENOG4108IPW	abc transporter atp-binding protein
A4A60_02265	ENOG4105R8C	Transcriptional regulator
A4A60_02270	ENOG4108DBC	nitroreductase
A4A60_02275	ENOG41067V3	Antibiotic biosynthesis monooxygenase
A4A60_02280	ENOG4105YVS	arsR family transcriptional regulator
A4A60_02290	ENOG4108JPW	Aminotransferase
A4A60_02295	ENOG4105C26	Dehydrogenase
A4A60_02305	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A4A60_02310	ENOG4105KTB	nuclear export factor GLE1
A4A60_02315	ENOG4108T5E	Copper resistance protein
A4A60_02320	ENOG4108ZYE	Transcriptional regulator
A4A60_02345	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A4A60_02350	ENOG4108ZX0	Signal peptidase I
A4A60_02365	ENOG4105DQ6	Transposase
A4A60_02385	ENOG4105E7W	lamb ycsf family protein
A4A60_02390	ENOG4105C5A	transporter
A4A60_02395	ENOG4105CFM	UPF0317 protein
A4A60_02400	ENOG4105P4J	Allophanate hydrolase, subunit 1
A4A60_02410	ENOG4107258	Transcriptional regulator
A4A60_02415	ENOG4105XJB	lipolytic protein G-D-S-L family
A4A60_02425	ENOG41061CK	Antibiotic biosynthesis monooxygenase
A4A60_02430	ENOG4107RVG	penicillin-binding protein
A4A60_02435	ENOG4107QM2	Aldo Keto reductase
A4A60_02440	ENOG4105ETD	TRANSCRIPTIONal
A4A60_02450	ENOG4105HMZ	Methyltransferase
A4A60_02455	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A4A60_02470	ENOG410606W	general stress protein
A4A60_02480	ENOG4105VCH	membrane
A4A60_02490	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4A60_02525	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
A4A60_02535	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
A4A60_02540	ENOG4105EU9	
A4A60_02545	ENOG4105QVS	general stress protein
A4A60_02550	ENOG41082W1	Cupin 2, conserved barrel domain protein
A4A60_02565	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A4A60_02570	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
A4A60_02575	ENOG4108MRH	transcriptional regulatory protein
A4A60_02580	ENOG4107QJT	sodium dicarboxylate symporter
A4A60_02585	ENOG4106F5Q	Membrane
A4A60_02595	ENOG4105CJ1	ABC, transporter
A4A60_02610	ENOG4105FDT	acyl-CoA dehydrogenase
A4A60_02630	ENOG4105SZ6	Thioredoxin
A4A60_02635	ENOG4105CPF	Cell wall formation (By similarity)
A4A60_02640	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
A4A60_02645	ENOG4105C1J	atp-dependent rna helicase
A4A60_02650	ENOG410905X	membrane-flanked domain protein
A4A60_02655	ENOG4105CKV	Membrane
A4A60_02665	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A4A60_02670	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
A4A60_02675	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A4A60_02685	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
A4A60_02690	ENOG4107MMM	Anti-sigma-factor antagonist
A4A60_02695	ENOG4105FUA	antagonist
A4A60_02700	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
A4A60_02705	ENOG4107SGM	protein serine threonine phosphatase
A4A60_02710	ENOG4105WN5	stage II sporulation protein
A4A60_02715	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
A4A60_02725	ENOG41064BQ	Phosphatase
A4A60_02785	ENOG4107V2S	Transcriptional regulator
A4A60_02800	ENOG4106BHF	
A4A60_02805	ENOG4105VZ8	Transcriptional regulator
A4A60_02830	ENOG4108V4B	ThiJ pfpI
A4A60_02835	ENOG4105VEQ	Cold shock protein
A4A60_02840	ENOG4108VJ1	Transcriptional regulator (CarD family
A4A60_02855	ENOG4108MCI	Transcriptional regulator, ARAC family
A4A60_02860	ENOG4108UZ3	Transporter
A4A60_02865	ENOG41086D8	Transcriptional regulator
A4A60_02870	ENOG4107U9B	transcriptional regulator
A4A60_02880	ENOG4105CZ9	Domain of unknown function (DU1801)
A4A60_02885	ENOG4105GIG	
A4A60_02895	ENOG4105KRI	phosphocarrier protein (HPr
A4A60_02900	ENOG4105ST3	Transcriptional regulator
A4A60_02905	ENOG4105T38	integral membrane protein
A4A60_02910	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4A60_02915	ENOG4108ZMQ	domain protein
A4A60_02920	ENOG4105MJ9	esterase
A4A60_02925	ENOG4107Z6X	Transcriptional regulator
A4A60_02935	ENOG41082YX	Transcriptional regulator, arsr family
A4A60_02940	ENOG4107R5R	arsenical pump membrane protein
A4A60_02950	ENOG4105Z7P	Acetyltransferase (GNAT) family
A4A60_02955	ENOG4107Y9U	Membrane
A4A60_02965	ENOG4105DY8	decarboxylase
A4A60_02970	ENOG4108SQ9	flavin reductase domain protein, FMN-binding
A4A60_02975	ENOG4108ZHR	arsR family transcriptional regulator
A4A60_02990	ENOG4105ENE	Histidine kinase
A4A60_02995	ENOG4108VB1	regulatoR
A4A60_03000	ENOG4105EYF	MMPL domain protein
A4A60_03010	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
A4A60_03015	ENOG4108UQV	Membrane
A4A60_03020	ENOG4108Z5V	transcriptional regulator, merr family
A4A60_03025	ENOG41076HS	cation diffusion facilitator family transporter
A4A60_03030	ENOG4108TVJ	Nitroreductase
A4A60_03035	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
A4A60_03040	ENOG4108VGI	doxx family
A4A60_03045	ENOG4105XXY	Thioredoxin
A4A60_03065	ENOG410900G	Protein of unknown function (DUF421)
A4A60_03070	ENOG4108QY0	Membrane
A4A60_03090	ENOG4105PF9	Transcriptional regulator
A4A60_03100	ENOG4105WQG	acetyltransferase
A4A60_03110	ENOG4105C85	amino acid
A4A60_03120	ENOG41062A4	Transcriptional regulator
A4A60_03125	ENOG4105EYF	MMPL domain protein
A4A60_03130	ENOG4108TVJ	Nitroreductase
A4A60_03135	ENOG4105FS7	Transcriptional regulator
A4A60_03140	ENOG4105C2C	drug resistance transporter, Bcr CflA
A4A60_03150	ENOG4105DRR	Transcriptional regulator, GntR family
A4A60_03155	ENOG4105VRS	hydrolase family 18
A4A60_03170	ENOG4105G6Z	alkaline phosphatase
A4A60_03175	ENOG4108ZMX	Domain of unknown function (DU1801)
A4A60_03185	ENOG4108YM7	Gcn5-related n-acetyltransferase
A4A60_03190	ENOG4107TVP	HD domain protein
A4A60_03195	ENOG41090UD	(LipO)protein
A4A60_03200	ENOG4105F27	Major Facilitator
A4A60_03205	ENOG4105VZJ	PTS System
A4A60_03220	ENOG4105CS2	ec 3.2.1.21
A4A60_03225	ENOG4108TZY	GntR Family Transcriptional Regulator
A4A60_03230	ENOG4105EVU	fructokinase
A4A60_03240	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
A4A60_03285	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A4A60_03290	ENOG4105K8N	protein family UPF0079, ATPase
A4A60_03295	ENOG41072GX	Peptidase M22 Glycoprotease
A4A60_03300	ENOG410801F	ribosomal-protein-alanine acetyltransferase
A4A60_03305	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A4A60_03310	ENOG4105C5H	ABC transporter
A4A60_03315	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A4A60_03320	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
A4A60_03325	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A4A60_03330	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A4A60_03340	ENOG4108TYN	CAAX amino terminal protease family protein
A4A60_03345	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A4A60_03350	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A4A60_03355	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A4A60_03360	ENOG410635T	phage-like element pbsx protein
A4A60_03440	ENOG4105QBX	endodeoxyribonuclease RusA
A4A60_03480	ENOG4107KNS	
A4A60_03520	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A4A60_03565	ENOG4108FKH	Transglycosylase SLT domain
A4A60_03575	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
A4A60_03585	ENOG41068G1	
A4A60_03605	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
A4A60_03665	ENOG4105PGZ	NB-ARC domain
A4A60_03670	ENOG4105CPQ	Dehydrogenase
A4A60_03675	ENOG4105CT4	transporter
A4A60_03685	ENOG41087YS	Phage shock protein A
A4A60_03690	ENOG4105DQX	Zinc finger domain
A4A60_03695	ENOG4108WV1	Pfam:DUF477
A4A60_03710	ENOG4107QNK	)-transporter
A4A60_03735	ENOG4105DQ6	Transposase
A4A60_03750	ENOG4107YUH	hydrolase
A4A60_03760	ENOG4107STQ	Multicopper oxidase
A4A60_03765	ENOG4105C85	amino acid
A4A60_03780	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A4A60_03810	ENOG4105C7N	Xanthine uracil vitamin C permease
A4A60_03840	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A4A60_03845	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A4A60_03850	ENOG4105C83	adenylosuccinate lyase
A4A60_03855	ENOG4105C8V	SAICAR synthetase
A4A60_03860	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
A4A60_03865	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A4A60_03870	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
A4A60_03880	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A4A60_03885	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A4A60_03890	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A4A60_03895	ENOG4105C12	Phosphoribosylglycinamide synthetase
A4A60_03920	ENOG4108R5T	secreted protein
A4A60_03925	ENOG4105KGF	protein, YerC YecD
A4A60_03930	ENOG4105CBC	glutamate synthase
A4A60_03940	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
A4A60_03945	ENOG4105C4R	Atp-dependent dna helicase
A4A60_03950	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A4A60_03960	ENOG4105CRN	Aminoglycoside phosphotransferase
A4A60_03965	ENOG4105KT7	mgtC SapB transporter
A4A60_03970	ENOG4105CK7	Sodium proline symporter
A4A60_03975	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A4A60_03980	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A4A60_03985	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A4A60_03990	ENOG4108IG5	Transcriptional regulator
A4A60_04000	ENOG4105CBD	Diacylglycerol kinase
A4A60_04005	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A4A60_04060	ENOG4108HFV	
A4A60_04080	ENOG4105CDY	transcriptional regulatory protein
A4A60_04090	ENOG4105M4P	Tetr family transcriptional regulator
A4A60_04095	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
A4A60_04100	ENOG4107S9F	NmrA family
A4A60_04115	ENOG4105WEF	catalase
A4A60_04120	ENOG4105M18	-acetyltransferase
A4A60_04135	ENOG4105C2F	Histidine kinase
A4A60_04145	ENOG410769Z	extracellular solute-binding protein family 1
A4A60_04155	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
A4A60_04160	ENOG4105F5H	Glycosyl Hydrolase Family 88
A4A60_04165	ENOG41075H3	AraC family transcriptional regulator
A4A60_04170	ENOG4107TDE	lipolytic protein G-D-S-L family
A4A60_04190	ENOG4105CX8	fg-gap repeat protein
A4A60_04195	ENOG4107TDE	lipolytic protein G-D-S-L family
A4A60_04210	ENOG4105E0S	extracellular solute-binding protein family 1
A4A60_04220	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
A4A60_04225	ENOG4105F8D	glycoside hydrolase family 4
A4A60_04230	ENOG4105H67	Protein of unknown function (DUF421)
A4A60_04235	ENOG4105Z26	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
A4A60_04240	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
A4A60_04260	ENOG4106I4J	membrane
A4A60_04265	ENOG41061H0	Monooxygenase
A4A60_04270	ENOG4106H3A	restriction
A4A60_04275	ENOG4108R1P	
A4A60_04280	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A4A60_04285	ENOG4105E0M	Sulfatase
A4A60_04290	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
A4A60_04300	ENOG41090R9	glycosyltransferase
A4A60_04305	ENOG4107R51	Glycosyl transferase, family 2
A4A60_04310	ENOG41090R9	glycosyltransferase
A4A60_04315	ENOG4105EU0	Major facilitator Superfamily
A4A60_04325	ENOG4105CUB	amino acid
A4A60_04330	ENOG4105C26	Dehydrogenase
A4A60_04335	ENOG4105FKZ	Methyl-accepting chemotaxis
A4A60_04340	ENOG4105C5H	ABC transporter
A4A60_04350	ENOG4107SWG	transcriptional regulator MERR family
A4A60_04355	ENOG4105DXB	Major Facilitator superfamily
A4A60_04370	ENOG4105DQ6	Transposase
A4A60_04375	ENOG4105C5H	ABC transporter
A4A60_04380	ENOG4105FDU	atp-dependent rna helicase
A4A60_04395	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
A4A60_04400	ENOG4105E0A	ABC, transporter
A4A60_04405	ENOG4108U1V	ABC transporter, permease
A4A60_04410	ENOG4105DQ5	transport system permease protein
A4A60_04415	ENOG4108HUF	Transporter
A4A60_04430	ENOG4108J20	pectate lyase
A4A60_04435	ENOG4107QPK	)-transporter
A4A60_04445	ENOG4108MRH	transcriptional regulatory protein
A4A60_04475	ENOG410855V	Acylphosphatase
A4A60_04480	ENOG4108RPX	mosc domain containing protein
A4A60_04500	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
A4A60_04520	ENOG4105E1K	spore germination protein
A4A60_04525	ENOG4105C5Y	PTS System
A4A60_04530	ENOG4105CG3	alpha amylase, catalytic region
A4A60_04535	ENOG4107414	GntR family transcriptional regulator
A4A60_04540	ENOG4108RCM	Nitroreductase
A4A60_04545	ENOG4105CGH	5'-nucleotidase
A4A60_04550	ENOG4107RKG	DJ-1/PfpI family
A4A60_04565	ENOG4105KJF	protein tyrosine phosphatase
A4A60_04575	ENOG4107U9T	Pfam:Ribonuclease_BN
A4A60_04585	ENOG4108ISG	Major Facilitator
A4A60_04595	ENOG4105UPD	Calcium Proton
A4A60_04605	ENOG4105D8X	mechanosensitive ion channel
A4A60_04625	ENOG4106KE4	Dehydrogenase
A4A60_04630	ENOG4105D7N	magnesium and cobalt transport protein CorA
A4A60_04640	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A4A60_04665	ENOG4107RUY	(E1 component), alpha subunit
A4A60_04675	ENOG4107QKR	Dehydrogenase
A4A60_04685	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
A4A60_04690	ENOG41069DP	small acid-soluble spore protein
A4A60_04695	ENOG4105KK4	UPF0060 membrane protein
A4A60_04725	ENOG4105F8D	glycoside hydrolase family 4
A4A60_04730	ENOG4108Q3X	Transcriptional regulator
A4A60_04735	ENOG4105CI1	PTS System
A4A60_04740	ENOG4105BZ1	(ABC) transporter
A4A60_04745	ENOG4105BZ1	(ABC) transporter
A4A60_04755	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4A60_04760	ENOG4105BZU	Histidine kinase
A4A60_04765	ENOG4105WH1	Two component transcriptional regulator luxr family
A4A60_04770	ENOG4105CJ1	ABC, transporter
A4A60_04775	ENOG41090VJ	ABC-2 type transporter
A4A60_04780	ENOG4108KYE	ABC-2 type transporter
A4A60_04785	ENOG4105U3E	Transcriptional regulator
A4A60_04790	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
A4A60_04795	ENOG4105H93	Acyltransferase family
A4A60_04800	ENOG4105YA8	Transcriptional regulator
A4A60_04805	ENOG4107Y80	Major Facilitator superfamily
A4A60_04810	ENOG4108YYS	metal-dependent hydrolase (By similarity)
A4A60_04820	ENOG410834F	Transcriptional regulator
A4A60_04830	ENOG4108MES	Periplasmic binding protein
A4A60_04835	ENOG4105DQ5	transport system permease protein
A4A60_04840	ENOG4108IHU	transport system permease protein
A4A60_04845	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A4A60_04850	ENOG4107Y03	Nitroreductase
A4A60_04865	ENOG4105ECP	epimerase
A4A60_04885	ENOG4105F27	Major Facilitator
A4A60_04905	ENOG4106AKJ	
A4A60_04910	ENOG4105D74	hydrolase
A4A60_04915	ENOG4105CKK	Glycosyl transferase, family 2
A4A60_04920	ENOG4105EJV	Membrane
A4A60_04925	ENOG41067AE	Membrane-bound metal-dependent hydrolase
A4A60_04930	ENOG4105CEN	a g-specific adenine glycosylase
A4A60_04935	ENOG4106BXE	
A4A60_04940	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
A4A60_04955	ENOG4105EVI	UPF0374 protein
A4A60_04960	ENOG4105BZ1	(ABC) transporter
A4A60_04965	ENOG4107NBY	Membrane
A4A60_04975	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4A60_04980	ENOG4105G5W	regulator Fur family
A4A60_05100	ENOG4105DQ6	Transposase
A4A60_05110	ENOG4108N23	SpoOM-related protein
A4A60_05125	ENOG4105EC3	peptidase S51, dipeptidase E
A4A60_05130	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A4A60_05150	ENOG4105E2Y	ABC, transporter
A4A60_05155	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
A4A60_05160	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A4A60_05165	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
A4A60_05175	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A4A60_05180	ENOG4107D63	
A4A60_05185	ENOG4105VZ8	Transcriptional regulator
A4A60_05200	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A4A60_05210	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A4A60_05230	ENOG4105CYN	Serine protein kinase
A4A60_05235	ENOG4106AKX	UPF0229 protein
A4A60_05245	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
A4A60_05250	ENOG4105CW7	secretion protein, HlyD family
A4A60_05255	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A4A60_05260	ENOG4105CS1	NAD(P)H quinone oxidoreductase
A4A60_05275	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
A4A60_05280	ENOG4105CZV	ABC transporter
A4A60_05285	ENOG4105CJ1	ABC, transporter
A4A60_05290	ENOG4108TU7	Inherit from COG: (ABC) transporter
A4A60_05295	ENOG4105VEQ	Cold shock protein
A4A60_05305	ENOG4105BZU	Histidine kinase
A4A60_05340	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
A4A60_05385	ENOG4105P1M	Domain of unknown function (DUF1874)
A4A60_05395	ENOG4105K4H	Nlp p60 protein
A4A60_05450	ENOG4108YBP	pseudouridine synthase
A4A60_05460	ENOG41080XP	Cbs domain
A4A60_05465	ENOG4107YBY	Hydrolase
A4A60_05470	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A4A60_05475	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A4A60_05480	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
A4A60_05490	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A4A60_05495	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A4A60_05505	ENOG4105BZU	Histidine kinase
A4A60_05510	ENOG4105WH1	Two component transcriptional regulator luxr family
A4A60_05550	ENOG4105ED1	spovr family
A4A60_05555	ENOG4105G6Z	alkaline phosphatase
A4A60_05570	ENOG4105BZN	citrate synthase
A4A60_05575	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A4A60_05580	ENOG4105CUB	amino acid
A4A60_05585	ENOG4105C8J	)-transporter
A4A60_05590	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4A60_05605	ENOG4105J37	
A4A60_05610	ENOG4108AEY	RNA polymerase sigma factor
A4A60_05615	ENOG4108FN7	Aldo keto reductase
A4A60_05620	ENOG4105F6E	Acyl-transferase
A4A60_05625	ENOG4105C37	(CBS) domain
A4A60_05640	ENOG4105C37	(CBS) domain
A4A60_05650	ENOG4105WMR	Protein CrcB homolog
A4A60_05655	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A4A60_05665	ENOG4105D64	Mechanosensitive ion channel
A4A60_05670	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A4A60_05675	ENOG4107VMI	polysaccharide deacetylase
A4A60_05680	ENOG4105F0I	Aminotransferase
A4A60_05700	ENOG4105BZ1	(ABC) transporter
A4A60_05705	ENOG4105BZ1	(ABC) transporter
A4A60_05725	ENOG410839P	
A4A60_05735	ENOG4106MP8	UPF0754 membrane protein
A4A60_05740	ENOG4105WZB	UPF0342 protein
A4A60_05755	ENOG4105D4P	Coproporphyrinogen iii oxidase
A4A60_05760	ENOG4107S91	Sodium hydrogen exchanger
A4A60_05765	ENOG4105NCW	Trka-c domain protein
A4A60_05775	ENOG4105CGU	Enoyl-CoA hydratase
A4A60_05785	ENOG4108IUX	(ABC) transporter
A4A60_05790	ENOG4105RHA	ABC transporter, permease
A4A60_05795	ENOG4107VRP	DNA repair exonuclease
A4A60_05800	ENOG4106D4I	domain protein
A4A60_05805	ENOG4105EQI	Metal Dependent Phosphohydrolase
A4A60_05815	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
A4A60_05850	ENOG4105NBU	tryptophan transport protein
A4A60_05855	ENOG4105DXJ	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A4A60_05860	ENOG4105K59	histidine triad (HIT) protein
A4A60_05895	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
A4A60_05900	ENOG4105BZ4	penicillin-binding protein
A4A60_05905	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A4A60_05910	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A4A60_05915	ENOG4105C1Q	protoporphyrinogen oxidase
A4A60_05925	ENOG4105ECB	domain protein
A4A60_05940	ENOG41090T1	Membrane
A4A60_05950	ENOG4105DER	m42 family
A4A60_05965	ENOG4106AXD	
A4A60_05970	ENOG4108RQ5	Beta-lactamase domain-containing protein
A4A60_05975	ENOG4105DF9	Lipoate-protein, ligase
A4A60_05985	ENOG4105CEY	Amp-dependent synthetase and ligase
A4A60_06000	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
A4A60_06010	ENOG4105KD7	acetyltransferase
A4A60_06020	ENOG4108HUF	Transporter
A4A60_06025	ENOG4105DQ6	Transposase
A4A60_06035	ENOG4107TB6	phosphoglycerate mutase
A4A60_06045	ENOG4107F3J	Amp-dependent synthetase and ligase
A4A60_06050	ENOG4107ZYJ	bioY protein
A4A60_06055	ENOG4106YBV	Methyl-accepting chemotaxis
A4A60_06075	ENOG4105XVF	Competence transcription factor
A4A60_06080	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A4A60_06085	ENOG4105X3H	Excalibur domain protein
A4A60_06090	ENOG4105E1V	na solute symporter
A4A60_06095	ENOG4106CAD	Protein of unknown function (DUF3311)
A4A60_06100	ENOG41060YP	
A4A60_06115	ENOG4107SCK	Monooxygenase
A4A60_06120	ENOG4108INS	Transcriptional regulator
A4A60_06145	ENOG4105TRI	Hydrolase
A4A60_06160	ENOG4108KK1	membrane protein AbrB duplication
A4A60_06165	ENOG4106K7D	Major facilitator family transporter
A4A60_06170	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
A4A60_06175	ENOG4105VWP	Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding
A4A60_06190	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
A4A60_06200	ENOG4105EYH	Exonuclease
A4A60_06255	ENOG4105ERH	Fumarylacetoacetate hydrolase
A4A60_06265	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4A60_06280	ENOG4105CAQ	asparagine synthetase
A4A60_06290	ENOG4105UQX	Mate efflux family protein
A4A60_06295	ENOG4106HBX	Transcriptional Regulator AraC Family
A4A60_06300	ENOG4105ETE	Transcriptional regulator (LacI family
A4A60_06305	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
A4A60_06310	ENOG4105SF0	DinB family
A4A60_06315	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
A4A60_06320	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4A60_06325	ENOG4105MYW	Pentapeptide repeat protein
A4A60_06330	ENOG4107S9D	Alpha beta hydrolase
A4A60_06340	ENOG4105MA6	gCN5-related N-acetyltransferase
A4A60_06350	ENOG4108VPT	UPF0234 protein
A4A60_06355	ENOG4105QNR	S1 RNA binding domain protein
A4A60_06375	ENOG4105K7K	Transcriptional regulator
A4A60_06385	ENOG410751J	
A4A60_06390	ENOG4105D4Y	metalloprotease
A4A60_06395	ENOG4105EPR	degv family
A4A60_06400	ENOG4107AYK	membrAne
A4A60_06410	ENOG41073B9	
A4A60_06420	ENOG4108KP7	hydrolase
A4A60_06425	ENOG4108MXZ	Esterase
A4A60_06430	ENOG4105VG1	fes assembly suf system protein
A4A60_06440	ENOG4105IQ5	FAD linked oxidase domain protein
A4A60_06450	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A4A60_06465	ENOG4105C8Y	Acetylornithine aminotransferase
A4A60_06470	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A4A60_06480	ENOG4105DBV	ornithine carbamoyltransferase
A4A60_06485	ENOG4105DQ6	Transposase
A4A60_06515	ENOG4107RMD	Basic membrane lipoprotein
A4A60_06530	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A4A60_06535	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A4A60_06545	ENOG4105C3U	ABC transporter
A4A60_06550	ENOG4108JQ7	(ABC) transporter
A4A60_06565	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4A60_06575	ENOG4105C31	Tryptophanyl-tRNA synthetase
A4A60_06580	ENOG4108J59	Extracellular solute-binding protein, family 5
A4A60_06585	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4A60_06590	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4A60_06600	ENOG4108JQ7	(ABC) transporter
A4A60_06615	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
A4A60_06620	ENOG4108ZCF	integral membrane protein
A4A60_06625	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
A4A60_06635	ENOG4105DPN	Oligoendopeptidase f
A4A60_06650	ENOG4105T58	Dithiol-disulfide isomerase
A4A60_06655	ENOG4108Z18	K06886 hemoglobin
A4A60_06660	ENOG4105E4C	Lytic transglycosylase catalytic
A4A60_06665	ENOG4105MIX	Adenylate cyclase
A4A60_06680	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A4A60_06685	ENOG4105EMS	pseudouridine synthase
A4A60_06700	ENOG4105ETU	transcriptional activator (TenA
A4A60_06705	ENOG4108VEU	Thiamine monophosphate synthase
A4A60_06720	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A4A60_06725	ENOG4105D06	uba thif-type nad fad binding protein
A4A60_06730	ENOG4105DWF	phosphomethylpyrimidine kinase
A4A60_06735	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A4A60_06740	ENOG4107A88	
A4A60_06795	ENOG4105ENA	helicase
A4A60_06810	ENOG4108ZMI	UPF0477 protein
A4A60_06820	ENOG4105C28	cystathionine
A4A60_06825	ENOG4105C28	cystathionine
A4A60_06830	ENOG4105D9U	N-acetyltransferase
A4A60_06835	ENOG4105JHY	Membrane
A4A60_06895	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
A4A60_06925	ENOG4107AUC	
A4A60_07005	ENOG4105DM4	PTS System
A4A60_07010	ENOG4105DG6	mannose-6-phosphate isomerase
A4A60_07015	ENOG4105G7B	Protein of unknown function (DUF2992)
A4A60_07025	ENOG4105VMI	-acetyltransferase
A4A60_07035	ENOG4108Z66	YbaK ebsC protein
A4A60_07050	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A4A60_07060	ENOG4108ZJ4	polysaccharide deacetylase
A4A60_07065	ENOG4107CUJ	Protein of unknown function (DUF2690)
A4A60_07095	ENOG4108IEG	Formate dehydrogenase Alpha subunit
A4A60_07125	ENOG4106A3M	Cytochrome p-450
A4A60_07130	ENOG41087PP	glycosyltransferase MGT family
A4A60_07140	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
A4A60_07155	ENOG4105C4B	ABC transporter, permease
A4A60_07160	ENOG4108IXI	(ABC) transporter
A4A60_07185	ENOG4105D2H	Uronic isomerase
A4A60_07195	ENOG4105DG4	malate L-lactate dehydrogenase
A4A60_07200	ENOG4105CPQ	Dehydrogenase
A4A60_07205	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
A4A60_07210	ENOG4105DMW	Dehydrogenase reductase
A4A60_07215	ENOG4108I5G	Major Facilitator superfamily
A4A60_07220	ENOG4107KJX	Transcriptional regulator
A4A60_07225	ENOG4107QZW	Altronate oxidoreductase
A4A60_07230	ENOG4105CTX	dehydratase
A4A60_07235	ENOG4107TSN	permease
A4A60_07250	ENOG4105JD4	ATPase yjob
A4A60_07255	ENOG4105DQ6	Transposase
A4A60_07265	ENOG4105JD4	ATPase yjob
A4A60_07285	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
A4A60_07290	ENOG4105KWG	Pfam:DUF1696
A4A60_07295	ENOG4105K7W	phage-related replication protein
A4A60_07300	ENOG4105WEF	catalase
A4A60_07305	ENOG410635T	phage-like element pbsx protein
A4A60_07355	ENOG4108TFU	terminase (Small subunit)
A4A60_07360	ENOG4105IG6	Phage terminase, large subunit
A4A60_07365	ENOG4108MDF	Phage Portal Protein
A4A60_07390	ENOG41060SN	
A4A60_07405	ENOG4105PQS	phage protein
A4A60_07410	ENOG4105FR7	XkdM protein, phage-like element PBSX
A4A60_07415	ENOG4105MTC	XkdN-like protein
A4A60_07425	ENOG4108FKH	Transglycosylase SLT domain
A4A60_07425	ENOG4108FKH	Transglycosylase SLT domain
A4A60_07425	ENOG4108FKH	Transglycosylase SLT domain
A4A60_07430	ENOG4108WZM	domain protein
A4A60_07435	ENOG4105X7F	
A4A60_07445	ENOG4105MFU	Protein of unknown function (DUF2634)
A4A60_07450	ENOG41066EA	baseplate J family protein
A4A60_07455	ENOG410906S	phage-like element pbsx protein xkdt
A4A60_07465	ENOG41068G1	
A4A60_07495	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
A4A60_07510	ENOG4105CJ3	phosphate transporter
A4A60_07515	ENOG4107GRR	phosphate transport regulator
A4A60_07525	ENOG4107R7I	amino acid
A4A60_07535	ENOG4105EDW	glycosyl transferase, family 39
A4A60_07540	ENOG4105CKK	Glycosyl transferase, family 2
A4A60_07550	ENOG4105C0H	protease
A4A60_07560	ENOG4108ME1	Peptidase M55 D-aminopeptidase
A4A60_07565	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4A60_07570	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4A60_07575	ENOG4105C3U	ABC transporter
A4A60_07585	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
A4A60_07590	ENOG4105DTQ	mandelate racemase muconate lactonizing
A4A60_07595	ENOG4107SN7	NLP P60 protein
A4A60_07600	ENOG4108JQ7	(ABC) transporter
A4A60_07605	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A4A60_07615	ENOG4108S4H	thioesterase Superfamily protein
A4A60_07620	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A4A60_07640	ENOG4108428	Inherit from COG: -acetyltransferase
A4A60_07650	ENOG41080TC	multidrug resistance protein
A4A60_07655	ENOG4105CIY	formyltetrahydrofolate deformylase
A4A60_07660	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A4A60_07675	ENOG4105K56	Transcriptional regulator
A4A60_07680	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A4A60_07690	ENOG4107Y2X	deaminase
A4A60_07695	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A4A60_07700	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4A60_07710	ENOG4108W7F	transporter, permease
A4A60_07715	ENOG4108JJB	ABC transporter
A4A60_07720	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
A4A60_07725	ENOG4108X43	YKOF domain protein
A4A60_07730	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4A60_07735	ENOG41062D9	Histidine kinase
A4A60_07745	ENOG4106849	propeptide, pepSY amd peptidase M4
A4A60_07765	ENOG4105CJW	magnesium transporter
A4A60_07770	ENOG4105V75	Transcriptional regulator
A4A60_07815	ENOG4105DQE	DNA ligase
A4A60_07820	ENOG4105FDF	Could be involved in DNA repair (By similarity)
A4A60_07825	ENOG4105BZU	Histidine kinase
A4A60_07830	ENOG4107T5V	SNARE associated Golgi
A4A60_07835	ENOG4107TS3	membrane protein, TerC
A4A60_07840	ENOG4108WZW	RNA polymerase sigma
A4A60_07850	ENOG410681C	small acid-soluble spore protein
A4A60_07860	ENOG4105D0M	Protease HtpX homolog
A4A60_07880	ENOG4108TGC	Acyltransferase
A4A60_07885	ENOG4105BZU	Histidine kinase
A4A60_07890	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A4A60_07900	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A4A60_07905	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
A4A60_07910	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A4A60_07920	ENOG4107T6J	Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit
A4A60_07925	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
A4A60_07930	ENOG4107V49	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
A4A60_07935	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
A4A60_07955	ENOG4105BZU	Histidine kinase
A4A60_07960	ENOG41090MY	MarR family Transcriptional regulator
A4A60_07965	ENOG4105ER2	Ompa motb domain protein
A4A60_07970	ENOG4105E14	MotA TolQ exbB proton channel
A4A60_07980	ENOG4108K88	Membrane
A4A60_07985	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A4A60_07990	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
A4A60_07995	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A4A60_08000	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
A4A60_08025	ENOG4105F0V	Cell wall hydrolase
A4A60_08040	ENOG4105C59	p-type ATPase
A4A60_08050	ENOG4105DC7	peptidase M24
A4A60_08065	ENOG4105CID	antiterminator
A4A60_08075	ENOG4105KRI	phosphocarrier protein (HPr
A4A60_08080	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A4A60_08090	ENOG4105F6S	Spore photoproduct lyase
A4A60_08100	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
A4A60_08105	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A4A60_08125	ENOG4105K4I	Scp-like extracellular
A4A60_08135	ENOG4105BZU	Histidine kinase
A4A60_08140	ENOG4105CHM	Aminotransferase
A4A60_08150	ENOG4107R88	Chemotaxis protein (CheV)
A4A60_08155	ENOG4105UIN	
A4A60_08165	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
A4A60_08175	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
A4A60_08180	ENOG4105EPM	Diguanylate phosphodiesterase
A4A60_08190	ENOG4107IN1	Protein of unknown function (DUF1797)
A4A60_08195	ENOG4108XRC	Protein of unknown function (DUF458) 
A4A60_08225	ENOG4105NQC	Flavodoxin
A4A60_08235	ENOG4105CH2	amidohydrolase
A4A60_08245	ENOG4105D8X	mechanosensitive ion channel
A4A60_08250	ENOG4105D3R	alkyl hydroperoxide reductase
A4A60_08255	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4A60_08265	ENOG4105DQ6	Transposase
A4A60_08280	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A4A60_08285	ENOG4105D06	uba thif-type nad fad binding protein
A4A60_08290	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A4A60_08295	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
A4A60_08300	ENOG4108ZAF	Molybdopterin
A4A60_08305	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
A4A60_08310	ENOG4105BZ1	(ABC) transporter
A4A60_08315	ENOG4105BZ1	(ABC) transporter
A4A60_08325	ENOG4107X8C	Efflux transporter RND family MFP subunit
A4A60_08330	ENOG4105C19	ABC transporter
A4A60_08335	ENOG4107RBB	ABC transporter, permease
A4A60_08340	ENOG4105E98	transcriptional regulator DeoR family
A4A60_08345	ENOG4105DE4	1-phosphofructokinase
A4A60_08350	ENOG4105DM4	PTS System
A4A60_08355	ENOG4105C3F	Signal peptidase i
A4A60_08365	ENOG4105C5H	ABC transporter
A4A60_08370	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A4A60_08400	ENOG4105BZU	Histidine kinase
A4A60_08410	ENOG4107ZYR	domain protein
A4A60_08420	ENOG4105CN5	Metallo-Beta-Lactamase
A4A60_08430	ENOG4108X4Q	Hydrolase
A4A60_08435	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A4A60_08455	ENOG4105CPP	Dehydrogenase, E1 component
A4A60_08460	ENOG4105C7S	Dehydrogenase
A4A60_08465	ENOG4107QN2	dihydrolipoyl dehydrogenase
A4A60_08485	ENOG4105CXN	decarboxylase
A4A60_08490	ENOG4105WBI	UPF0223 protein
A4A60_08505	ENOG4105ECY	inositol monophosphatase
A4A60_08515	ENOG4105JQZ	Methyltransferase
A4A60_08560	ENOG4105CI3	gtp-binding protein typa
A4A60_08565	ENOG4105QA2	
A4A60_08580	ENOG4108IAB	Phoh family
A4A60_08590	ENOG4105CSV	Glutaminase
A4A60_08595	ENOG4105ZPI	UPF0358 protein
A4A60_08600	ENOG4105CNI	cell division protein FtsW
A4A60_08605	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
A4A60_08620	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A4A60_08630	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A4A60_08635	ENOG4105CCU	oxidase (Subunit III)
A4A60_08640	ENOG41064X9	cytochrome C oxidase subunit IV
A4A60_08655	ENOG41080XQ	Signal transduction protein with cbs domains
A4A60_08660	ENOG4106UY4	Inherit from COG: Scp-like extracellular
A4A60_08680	ENOG4105WUC	UPF0298 protein
A4A60_08685	ENOG4106H78	methyltransferase
A4A60_08690	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A4A60_08695	ENOG4105H20	Sporulation integral membrane protein YlbJ
A4A60_08700	ENOG4105D78	K07001 NTE family protein
A4A60_08705	ENOG41063PX	domain protein
A4A60_08710	ENOG4105CDE	UPF0348 protein
A4A60_08720	ENOG4105KNH	Nucleic acid-binding protein
A4A60_08725	ENOG41067VY	50S ribosomal protein L32
A4A60_08750	ENOG4108V6E	Cell division protein mraZ
A4A60_08755	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A4A60_08765	ENOG4105CJN	penicillin-binding protein
A4A60_08775	ENOG4105CJN	penicillin-binding protein
A4A60_08785	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A4A60_08795	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A4A60_08800	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A4A60_08805	ENOG4105CNI	cell division protein FtsW
A4A60_08810	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A4A60_08815	ENOG4105D4A	Cell wall formation (By similarity)
A4A60_08820	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
A4A60_08825	ENOG4108R2U	division initiation protein
A4A60_08835	ENOG4105K67	small basic protein
A4A60_08840	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A4A60_08845	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A4A60_08855	ENOG4105FFI	sigma-e processing peptidase spoiiga
A4A60_08860	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4A60_08870	ENOG4105DKW	ABC transporter
A4A60_08880	ENOG4105WR5	sporulation protein, YlmC YmxH family
A4A60_08885	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A4A60_08890	ENOG4105DFA	alanine racemase domain protein
A4A60_08895	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
A4A60_08900	ENOG41067XK	integral membrane protein
A4A60_08905	ENOG4105DBK	s4 domain protein
A4A60_08915	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A4A60_08930	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A4A60_08935	ENOG4105C34	Pseudouridine synthase
A4A60_08940	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
A4A60_08950	ENOG4105CXT	aspartate transcarbamylase
A4A60_08960	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A4A60_08965	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A4A60_08970	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A4A60_08975	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A4A60_08980	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A4A60_08985	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A4A60_08990	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A4A60_09000	ENOG4107S4M	Sulfate adenylate transferase
A4A60_09005	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
A4A60_09010	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A4A60_09015	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
A4A60_09020	ENOG41087GM	Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein
A4A60_09025	ENOG4105F23	Fibronectin-binding protein
A4A60_09035	ENOG4105DSJ	YicC domain protein
A4A60_09040	ENOG4105KC4	UPF0296 protein
A4A60_09045	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A4A60_09055	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A4A60_09060	ENOG4105C25	Primosomal protein n'
A4A60_09065	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A4A60_09070	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A4A60_09075	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A4A60_09080	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A4A60_09085	ENOG4108ZF3	Phosphatase
A4A60_09090	ENOG4105D9P	serine threonine protein kinase
A4A60_09095	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A4A60_09100	ENOG4105DJV	ribulose-phosphate 3-epimerase
A4A60_09105	ENOG4105FJ0	thiamine
A4A60_09115	ENOG4105VB9	50S ribosomal protein l28
A4A60_09120	ENOG4108ZAA	Alkaline-shock protein
A4A60_09125	ENOG4105DP4	dak2 domain fusion protein ylov
A4A60_09135	ENOG4105EJQ	L-serine dehydratase
A4A60_09140	ENOG4105CB5	ATP-dependent DNA helicase recG
A4A60_09145	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
A4A60_09155	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A4A60_09160	ENOG4105CHR	reductase
A4A60_09165	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A4A60_09170	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A4A60_09175	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A4A60_09180	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A4A60_09190	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
A4A60_09200	ENOG4105K5M	30s ribosomal protein S16
A4A60_09205	ENOG4108BW8	UPF0109 protein
A4A60_09215	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A4A60_09220	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A4A60_09225	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A4A60_09230	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A4A60_09235	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A4A60_09245	ENOG4105VM1	flagellar
A4A60_09250	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A4A60_09255	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A4A60_09260	ENOG4105C79	DNA protecting protein DprA
A4A60_09265	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A4A60_09270	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
A4A60_09275	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A4A60_09280	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A4A60_09285	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A4A60_09295	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
A4A60_09300	ENOG4108ZC9	flagellar basal-body rod protein flgc
A4A60_09305	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
A4A60_09310	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
A4A60_09315	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A4A60_09330	ENOG4106YF4	Flagellar biosynthesis chaperone
A4A60_09340	ENOG410696Y	Flagellar hook-length control protein
A4A60_09345	ENOG410822I	Flagellar hook capping protein
A4A60_09350	ENOG4108JQA	flagellar
A4A60_09355	ENOG41068WV	flagellar FlbD family protein
A4A60_09365	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A4A60_09370	ENOG4105DD5	Flagellar motor switch protein
A4A60_09375	ENOG4107YTP	response regulator receiver protein
A4A60_09385	ENOG4105CN7	Flagellar biosynthetic protein FliP
A4A60_09390	ENOG4105VS8	Flagellar biosynthetic protein fliq
A4A60_09395	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
A4A60_09400	ENOG4105D00	flagellar biosynthetic protein flhB
A4A60_09405	ENOG4105D7B	Flagellar biosynthesis protein flha
A4A60_09410	ENOG4105FZW	flagellar biosynthesis regulator FlhF
A4A60_09420	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A4A60_09425	ENOG4105CBS	Chea signal transduction histidine kinase
A4A60_09430	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
A4A60_09445	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4A60_09455	ENOG4105CE9	30S ribosomal protein S2
A4A60_09460	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A4A60_09470	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A4A60_09475	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A4A60_09480	ENOG4105KNE	Phosphatidate cytidylyltransferase
A4A60_09490	ENOG4105DZP	Membrane-associated zinc metalloprotease
A4A60_09495	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A4A60_09500	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A4A60_09505	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A4A60_09510	ENOG4105CHV	Transcription elongation factor NusA
A4A60_09515	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
A4A60_09520	ENOG4105VHM	ribosomal protein
A4A60_09525	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A4A60_09530	ENOG4105W7A	Protein of unknown function (DUF503)
A4A60_09535	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A4A60_09540	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A4A60_09545	ENOG4105DTN	riboflavin biosynthesis protein ribF
A4A60_09550	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A4A60_09555	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A4A60_09565	ENOG4105C1V	Peptidase, M16
A4A60_09580	ENOG4105E35	Dipicolinate synthase subunit A
A4A60_09585	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
A4A60_09590	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A4A60_09600	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A4A60_09610	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
A4A60_09620	ENOG4105CNU	cell division protein FtsK
A4A60_09625	ENOG4105FDP	GntR family transcriptional regulator
A4A60_09645	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
A4A60_09650	ENOG4105XZV	Protein of unknown function (DUF3243)
A4A60_09665	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A4A60_09670	ENOG4105CEV	competence damage-inducible protein
A4A60_09680	ENOG4108A04	Beta-lactamase
A4A60_09685	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
A4A60_09690	ENOG4105D48	metallophosphoesterase
A4A60_09695	ENOG4105MCT	stage V sporulation protein S
A4A60_09705	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A4A60_09715	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A4A60_09730	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A4A60_09735	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A4A60_09835	ENOG4105IIP	Membrane
A4A60_09840	ENOG4105W1N	transcriptional regulator
A4A60_09855	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4A60_09865	ENOG4105K7W	phage-related replication protein
A4A60_09870	ENOG4108X3M	OsmC Ohr family protein
A4A60_09875	ENOG410814C	multidrug resistance protein
A4A60_09895	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A4A60_09900	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A4A60_09915	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
A4A60_09920	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A4A60_09925	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A4A60_09930	ENOG4105U6W	MutT NUDIX family protein
A4A60_09935	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A4A60_09940	ENOG4106F1P	AAA ATPase, central domain protein
A4A60_09950	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A4A60_09955	ENOG4105CXI	aluminum resistance protein
A4A60_09960	ENOG4105KV4	Transcriptional regulator
A4A60_09965	ENOG4105C5F	glutamine synthetase
A4A60_09980	ENOG4106BHF	
A4A60_09990	ENOG41079P0	
A4A60_10045	ENOG4107NTZ	
A4A60_10070	ENOG410907G	
A4A60_10075	ENOG4105CT4	transporter
A4A60_10080	ENOG4105DSG	hydrolase family 43
A4A60_10085	ENOG4105E2R	ROK family
A4A60_10090	ENOG4105C93	Xylose Isomerase
A4A60_10095	ENOG4105CMG	Carbohydrate kinase
A4A60_10105	ENOG4107Y9E	nuclease
A4A60_10110	ENOG4105C54	Major Facilitator superfamily
A4A60_10115	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A4A60_10130	ENOG4107YUK	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
A4A60_10220	ENOG4105FVX	
A4A60_10230	ENOG4105K7W	phage-related replication protein
A4A60_10240	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
A4A60_10250	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A4A60_10260	ENOG4108SVB	resolvase
A4A60_10265	ENOG4105VPS	UPF0291 protein
A4A60_10270	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A4A60_10290	ENOG4107QIV	Cytochrome c biogenesis protein
A4A60_10305	ENOG4105DQ6	Transposase
A4A60_10325	ENOG4107DZX	Small, acid-soluble spore protein P
A4A60_10335	ENOG4108I0Z	Aconitate hydratase
A4A60_10340	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4A60_10355	ENOG41067CD	Small, acid-soluble spore protein Tlp
A4A60_10365	ENOG4105MI2	
A4A60_10370	ENOG4105W8X	HesB YadR YfhF-family protein
A4A60_10375	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A4A60_10380	ENOG4105K4P	CoA-binding domain protein
A4A60_10385	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4A60_10410	ENOG4107QWR	cellulase (EC 3.2.1.4)
A4A60_10435	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A4A60_10440	ENOG4107T5V	SNARE associated Golgi
A4A60_10450	ENOG4107QX3	carboxylase
A4A60_10455	ENOG4105E39	Enoyl-CoA hydratase
A4A60_10460	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
A4A60_10465	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
A4A60_10470	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A4A60_10475	ENOG4105CEY	Amp-dependent synthetase and ligase
A4A60_10480	ENOG4105C1G	acyl-Coa dehydrogenase
A4A60_10490	ENOG4105F32	YngK protein
A4A60_10495	ENOG4106U2H	Protein of unknown function (DUF1360)
A4A60_10505	ENOG4105CEY	Amp-dependent synthetase and ligase
A4A60_10510	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
A4A60_10515	ENOG4108N2V	aldose 1-epimerase
A4A60_10520	ENOG4107QJQ	Mate efflux family protein
A4A60_10545	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A4A60_10550	ENOG4105SKE	transcriptional Regulator LysR family
A4A60_10555	ENOG4105CB2	alcohol dehydrogenase
A4A60_10560	ENOG4105BZ8	glutamate synthase
A4A60_10565	ENOG4105CBC	glutamate synthase
A4A60_10570	ENOG4105C5Q	Transcriptional regulator
A4A60_10605	ENOG4108UB7	
A4A60_10610	ENOG41068WN	
A4A60_10625	ENOG4105CJ1	ABC, transporter
A4A60_10635	ENOG4105IE8	Alpha-ketoglutarate permease
A4A60_10650	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A4A60_10660	ENOG4108QY0	Membrane
A4A60_10675	ENOG4105CZ3	stage V sporulation protein ad
A4A60_10680	ENOG41090VF	Stage v sporulation protein ac
A4A60_10690	ENOG4105WEF	catalase
A4A60_10705	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A4A60_10720	ENOG4105EC8	Methyl-accepting chemotaxis
A4A60_10730	ENOG4108YQE	rare lipoprotein a
A4A60_10735	ENOG4105XPP	Protein of unknown function (DUF1275)
A4A60_10755	ENOG4105F0F	Oxalate decarboxylase
A4A60_10775	ENOG41073R8	VanW family
A4A60_10785	ENOG4105VMP	Transcriptional regulator
A4A60_10790	ENOG4105NX3	Membrane
A4A60_10800	ENOG4108Q5Y	Membrane
A4A60_10810	ENOG4108V4B	ThiJ pfpI
A4A60_10815	ENOG4108J4B	Beta-lactamase
A4A60_10835	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A4A60_10840	ENOG4107T94	Endo-14-beta-xylanase
A4A60_10845	ENOG4105YB8	TM2 domain containing protein
A4A60_10850	ENOG4108IMY	Transcriptional regulator
A4A60_10885	ENOG4106QJ6	Integrase catalytic subunit
A4A60_10890	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
A4A60_10935	ENOG4107NTZ	
A4A60_10985	ENOG4105D9U	N-acetyltransferase
A4A60_10995	ENOG4105D06	uba thif-type nad fad binding protein
A4A60_11000	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4A60_11040	ENOG4105UA4	acetyltransferase
A4A60_11055	ENOG4106ANW	SMI1_KNR4
A4A60_11060	ENOG4106BHF	
A4A60_11075	ENOG4108Z7R	Chaperone CsaA
A4A60_11080	ENOG4105FTV	AraC Family Transcriptional Regulator
A4A60_11085	ENOG4108HJF	gCN5-related N-acetyltransferase
A4A60_11095	ENOG4108W8B	Beta-lactamase domain protein
A4A60_11105	ENOG4105D29	Helix-turn-helix type 11 domain protein
A4A60_11115	ENOG4105KTU	Transcriptional regulator, arsr family
A4A60_11135	ENOG4108SJC	Membrane
A4A60_11155	ENOG4105ECK	Fatty Acid Desaturase
A4A60_11160	ENOG4108ZGX	Histidine kinase
A4A60_11165	ENOG4108S01	response regulator
A4A60_11170	ENOG41069ER	domain protein
A4A60_11175	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4A60_11190	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A4A60_11195	ENOG4105SCY	DNAK suppressor
A4A60_11240	ENOG4105C26	Dehydrogenase
A4A60_11245	ENOG4105EWU	Squalene--hopene cyclase
A4A60_11250	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A4A60_11255	ENOG4105C8J	)-transporter
A4A60_11260	ENOG4105C09	Bile acid
A4A60_11265	ENOG4105C7S	Dehydrogenase
A4A60_11275	ENOG4107T89	von Willebrand factor, type A
A4A60_11280	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
A4A60_11290	ENOG4105K4H	Nlp p60 protein
A4A60_11295	ENOG41087PP	glycosyltransferase MGT family
A4A60_11305	ENOG4107QMU	Mate efflux family protein
A4A60_11310	ENOG4106SCS	STAS domain
A4A60_11330	ENOG4105FR1	rard protein
A4A60_11345	ENOG4105C6Z	Gluconate
A4A60_11350	ENOG41090U3	tautomerase
A4A60_11365	ENOG4105FBA	Phospholipase Carboxylesterase
A4A60_11380	ENOG4105E1V	na solute symporter
A4A60_11400	ENOG4108VXD	carboxy-peptidase
A4A60_11405	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
A4A60_11415	ENOG4106Z5R	
A4A60_11420	ENOG410841Q	phosphoesterase PA-phosphatase related protein
A4A60_11455	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
A4A60_11460	ENOG4108TSC	N-acetyltransferase
A4A60_11465	ENOG4107S4Y	M20 DapE family protein YgeY
A4A60_11480	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A4A60_11520	ENOG4107T32	3-phytase (EC 3.1.3.8)
A4A60_11525	ENOG4105C5E	polysaccharide biosynthesis protein
A4A60_11530	ENOG4105E0X	reductase
A4A60_11535	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A4A60_11555	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
A4A60_11560	ENOG41090WU	lipolytic protein G-D-S-L family
A4A60_11565	ENOG4108KF3	Electron transport protein SCO1 SenC
A4A60_11580	ENOG4105C7B	Threonine dehydratase
A4A60_11590	ENOG4108UT2	hemolysin iii
A4A60_11600	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
A4A60_11615	ENOG4107YX5	Pfam:DUF548
A4A60_11620	ENOG4108Y6J	UPF0403 protein
A4A60_11625	ENOG4105C01	Dihydroxy-acid dehydratase
A4A60_11640	ENOG4108V06	Glutathione peroxidase
A4A60_11645	ENOG4105CVG	Homoserine O-transsuccinylase
A4A60_11685	ENOG41081VK	Ribonuclease
A4A60_11715	ENOG410890F	Dynamin family
A4A60_11730	ENOG4105C2W	permease
A4A60_11735	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
A4A60_11740	ENOG4105CTD	carboxy-peptidase
A4A60_11745	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
A4A60_11750	ENOG4108UHU	Aldolase
A4A60_11755	ENOG4105D7K	pfkb domain protein
A4A60_11760	ENOG4108M60	Transcriptional regulator
A4A60_11770	ENOG4105CHR	reductase
A4A60_11775	ENOG4105DVT	helicase
A4A60_11785	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A4A60_11800	ENOG4108UKS	UPF0398 protein
A4A60_11810	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
A4A60_11815	ENOG4108I5C	dEAD DEAH box helicase
A4A60_11865	ENOG4105BZ4	penicillin-binding protein
A4A60_11875	ENOG4105CSM	endonuclease III
A4A60_11885	ENOG4105C5S	asparaginyl-tRNA synthetase
A4A60_11890	ENOG4105CHM	Aminotransferase
A4A60_11900	ENOG4105YAC	
A4A60_11905	ENOG4105DVT	helicase
A4A60_11910	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
A4A60_11915	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A4A60_11920	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A4A60_11925	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A4A60_11930	ENOG4105DJ0	Poly(A) Polymerase
A4A60_11935	ENOG4105CPK	Glycosyl transferase (Group 1
A4A60_11940	ENOG4105FJR	Lmbe family
A4A60_11945	ENOG4108Z5K	methylglyoxal synthase
A4A60_11950	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A4A60_11955	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
A4A60_11960	ENOG4108JYZ	YitT family
A4A60_11980	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A4A60_12000	ENOG41068YB	TPR repeat-containing protein
A4A60_12005	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A4A60_12025	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A4A60_12030	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
A4A60_12040	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A4A60_12045	ENOG4105CRQ	synthase (Component I)
A4A60_12050	ENOG4105KHN	chorismate mutase
A4A60_12055	ENOG4105D49	3-dehydroquinate synthase
A4A60_12060	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A4A60_12065	ENOG4105BZU	Histidine kinase
A4A60_12075	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A4A60_12080	ENOG4105EAH	synthase
A4A60_12085	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4A60_12090	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
A4A60_12100	ENOG4105EUJ	GTP cyclohydrolase i
A4A60_12115	ENOG4105K70	DNA-binding protein
A4A60_12120	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
A4A60_12135	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A4A60_12140	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A4A60_12145	ENOG41065D1	
A4A60_12150	ENOG4105S2F	
A4A60_12165	ENOG4105DQ6	Transposase
A4A60_12175	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A4A60_12180	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A4A60_12185	ENOG4105CAT	Cytidine monophosphate kinase
A4A60_12200	ENOG4105MSI	germination protein ypeb
A4A60_12210	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
A4A60_12215	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
A4A60_12230	ENOG4107RGJ	metallophosphoesterase
A4A60_12245	ENOG4105I7S	Abortive infection protein
A4A60_12250	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4A60_12255	ENOG4105T7X	
A4A60_12265	ENOG4108SAX	Membrane
A4A60_12270	ENOG4108JQ1	Dehydrogenase
A4A60_12275	ENOG4105FF2	Type I DHQase
A4A60_12290	ENOG4105BZU	Histidine kinase
A4A60_12295	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4A60_12300	ENOG4105CRE	cytochrome C
A4A60_12305	ENOG4107TWT	Cytochrome c biogenesis protein
A4A60_12315	ENOG4105FE9	pseudouridine synthase
A4A60_12325	ENOG4108JIC	nucleoside recognition domain protein
A4A60_12330	ENOG4105DZ1	carboxypeptidase
A4A60_12340	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A4A60_12345	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A4A60_12360	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A4A60_12365	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A4A60_12370	ENOG4108R6K	riboflavin synthase, subunit alpha
A4A60_12375	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A4A60_12385	ENOG4105C3F	Signal peptidase i
A4A60_12390	ENOG4105VES	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
A4A60_12485	ENOG4107ZE5	PPIases accelerate the folding of proteins
A4A60_12495	ENOG4105PTM	secreted protein
A4A60_12500	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A4A60_12510	ENOG4105G6R	Stage v sporulation protein ae
A4A60_12520	ENOG4105CZ3	stage V sporulation protein ad
A4A60_12525	ENOG41090VF	Stage v sporulation protein ac
A4A60_12540	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4A60_12545	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
A4A60_12550	ENOG41082AN	stage II sporulation protein
A4A60_12555	ENOG4105DZ1	carboxypeptidase
A4A60_12560	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A4A60_12565	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
A4A60_12570	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A4A60_12580	ENOG4105I3K	Ferric uptake regulator, Fur family
A4A60_12585	ENOG4105MZ9	stage II sporulation protein m
A4A60_12600	ENOG4105DFD	Na H antiporter
A4A60_12605	ENOG4108IJ0	Aspartate ammonia-lyase
A4A60_12610	ENOG4105HDK	L-asparaginase
A4A60_12615	ENOG4108IMY	Transcriptional regulator
A4A60_12625	ENOG4108YZ4	nudix hydrolase
A4A60_12635	ENOG4105CPC	Aldo Keto reductase
A4A60_12655	ENOG4106HZJ	
A4A60_12660	ENOG4105RHY	Pfam:UPF0157
A4A60_12665	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
A4A60_12670	ENOG4108XET	gCN5-related N-acetyltransferase
A4A60_12680	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A4A60_12690	ENOG4105E5W	Transporter
A4A60_12700	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4A60_12715	ENOG4108IXY	short-chain dehydrogenase reductase
A4A60_12720	ENOG41069FQ	Metallo-beta-lactamase superfamily
A4A60_12725	ENOG4105II7	pyrroline-5-carboxylate reductase
A4A60_12740	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A4A60_12750	ENOG410861F	50S ribosomal protein L33
A4A60_12755	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A4A60_12760	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A4A60_12765	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A4A60_12770	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A4A60_12780	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
A4A60_12785	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
A4A60_12790	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A4A60_12795	ENOG4108HNZ	carboxyl transferase
A4A60_12800	ENOG4108ZVT	methylmalonyl-coA epimerase
A4A60_12810	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
A4A60_12815	ENOG4108QEG	Membrane
A4A60_12820	ENOG4105CDA	abc transporter atp-binding protein
A4A60_12825	ENOG4105E5Q	amino acid AbC transporter
A4A60_12830	ENOG4108HW3	(ABC) transporter
A4A60_12835	ENOG4108Y6J	UPF0403 protein
A4A60_12840	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
A4A60_12855	ENOG4105C7S	Dehydrogenase
A4A60_12860	ENOG4105CPP	Dehydrogenase, E1 component
A4A60_12875	ENOG4105CKM	Branched-chain carboxylic acid kinase
A4A60_12880	ENOG4107RDP	Dehydrogenase
A4A60_12890	ENOG4108JUB	Transcriptional regulator
A4A60_12895	ENOG4106CCJ	Protein of unknown function (DUF2627)
A4A60_12900	ENOG4105CR4	methylisocitrate lyase
A4A60_12905	ENOG4105DXD	2-methylcitrate dehydratase
A4A60_12915	ENOG4105C1G	acyl-Coa dehydrogenase
A4A60_12920	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A4A60_12930	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A4A60_12935	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A4A60_12950	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A4A60_12960	ENOG4107QQR	Sporulation
A4A60_12970	ENOG4105S1Z	Stage IV sporulation protein B
A4A60_12975	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A4A60_12980	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
A4A60_12985	ENOG4105DX0	Hemolysin A
A4A60_12995	ENOG4105CTB	Polyprenyl synthetase
A4A60_13000	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A4A60_13005	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A4A60_13010	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A4A60_13015	ENOG4105M7K	Involved in the transcription termination process (By similarity)
A4A60_13020	ENOG4108ZSR	alkaline shock protein
A4A60_13025	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A4A60_13045	ENOG410644B	Stage III sporulation protein af
A4A60_13055	ENOG4105KQ4	Stage iii sporulation protein ad
A4A60_13060	ENOG4108CQH	stage III sporulation protein AC
A4A60_13065	ENOG4105KR5	Stage iii sporulation protein
A4A60_13070	ENOG4105CD2	stage iii sporulation protein aa
A4A60_13080	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A4A60_13085	ENOG4105DC7	peptidase M24
A4A60_13090	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A4A60_13100	ENOG4105CBJ	Metal-dependent enzyme
A4A60_13115	ENOG4105KST	dependent repressor
A4A60_13120	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
A4A60_13125	ENOG4105WZW	rhodanese family
A4A60_13130	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A4A60_13135	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A4A60_13140	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A4A60_13145	ENOG4105C0D	helicase
A4A60_13160	ENOG4108IMY	Transcriptional regulator
A4A60_13170	ENOG4105VFR	signal peptidase
A4A60_13230	ENOG41080XP	Cbs domain
A4A60_13240	ENOG4105C37	(CBS) domain
A4A60_13270	ENOG4105C5X	domain protein
A4A60_13295	ENOG4105E0M	Sulfatase
A4A60_13310	ENOG4107ZXI	Rhomboid family
A4A60_13320	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A4A60_13325	ENOG4105WDJ	50S ribosomal protein L33
A4A60_13345	ENOG41068DG	YceG-like family
A4A60_13350	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A4A60_13355	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A4A60_13360	ENOG4105E2Z	phosphate ABC transporter (Permease
A4A60_13365	ENOG4105C8U	phosphate abc transporter
A4A60_13370	ENOG4105CVA	phosphate
A4A60_13375	ENOG4107RF6	penicillin-binding protein
A4A60_13385	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A4A60_13390	ENOG4105SXS	Protein of unknown function (DUF456)
A4A60_13405	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A4A60_13410	ENOG41063Y9	
A4A60_13415	ENOG4108U5J	'-nucleotidase
A4A60_13420	ENOG4105N80	Ferric uptake regulator, Fur family
A4A60_13425	ENOG4108JYZ	YitT family
A4A60_13430	ENOG41069ZM	Protein of unknown function (DUF2624)
A4A60_13435	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
A4A60_13450	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A4A60_13455	ENOG4105EGD	dinuclear metal center protein, YbgI family
A4A60_13470	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4A60_13475	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A4A60_13480	ENOG41082VT	Uncharacterized BCR, YaiI/YqxD family COG1671
A4A60_13485	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
A4A60_13495	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A4A60_13500	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
A4A60_13505	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
A4A60_13515	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A4A60_13520	ENOG4105KG3	cytidine deaminase
A4A60_13525	ENOG4107YR5	Diacylglycerol kinase
A4A60_13530	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A4A60_13535	ENOG4105CTJ	Metal Dependent Phosphohydrolase
A4A60_13545	ENOG4105C9A	Phoh family
A4A60_13550	ENOG4105EI1	sporulation protein yqfd
A4A60_13555	ENOG41068P3	sporulation protein YqfC
A4A60_13565	ENOG4105DI5	UPF0365 protein
A4A60_13570	ENOG4105F7J	membrane-bound serine protease
A4A60_13575	ENOG4105KTH	gatB Yqey
A4A60_13590	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A4A60_13595	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A4A60_13600	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A4A60_13610	ENOG4105CFG	Acts as a chaperone (By similarity)
A4A60_13615	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A4A60_13620	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
A4A60_13625	ENOG4105CSA	Coproporphyrinogen iii oxidase
A4A60_13630	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A4A60_13640	ENOG4108ZRV	stage ii sporulation protein p
A4A60_13645	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
A4A60_13650	ENOG41082YS	Binds directly to 16S ribosomal RNA
A4A60_13655	ENOG4105TQK	DNA polymerase iii, delta' subunit
A4A60_13665	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
A4A60_13670	ENOG4108UK2	deaminase
A4A60_13675	ENOG4105KQC	Competence protein
A4A60_13685	ENOG4108D32	Methyltransferase
A4A60_13695	ENOG4108WF2	Metal Dependent Phosphohydrolase
A4A60_13700	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A4A60_13705	ENOG410812S	Rna-binding protein
A4A60_13710	ENOG4105E2X	shikimate dehydrogenase
A4A60_13715	ENOG4105CQW	ribosome biogenesis GTPase YqeH
A4A60_13720	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
A4A60_13740	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
A4A60_13745	ENOG41080BT	SNARE associated Golgi
A4A60_13760	ENOG4105WFK	nuclease
A4A60_13765	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4A60_13780	ENOG4105C9Q	fumarate hydratase class II
A4A60_13785	ENOG4107RSM	transcriptional regulator
A4A60_13850	ENOG4106QJ6	Integrase catalytic subunit
A4A60_13855	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
A4A60_13900	ENOG41090E6	transcriptional regulator MERR family
A4A60_13920	ENOG4105C37	(CBS) domain
A4A60_13935	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
A4A60_13940	ENOG4105H3G	oxidoreductase
A4A60_13945	ENOG4105PGM	cation diffusion facilitator family transporter
A4A60_13965	ENOG4105KMT	branched-chain amino acid
A4A60_13970	ENOG4108UMN	azlc family
A4A60_13975	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
A4A60_13980	ENOG41067XF	inhibitor
A4A60_13995	ENOG41064BW	Protein of unknown function (DUF2568)
A4A60_14005	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
A4A60_14010	ENOG4105EA8	2-Nitropropane dioxygenase
A4A60_14015	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A4A60_14030	ENOG4108MEK	Metal-binding protein YodA
A4A60_14035	ENOG410904A	RNA polymerase
A4A60_14040	ENOG4105CPC	Aldo Keto reductase
A4A60_14045	ENOG41083Q9	chitosanase
A4A60_14050	ENOG4105X5K	response regulator receiver protein
A4A60_14055	ENOG4108VQT	Alpha beta hydrolase fold protein
A4A60_14060	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
A4A60_14065	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
A4A60_14070	ENOG4105Z0X	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4A60_14080	ENOG4105PGS	Spore coat protein
A4A60_14085	ENOG4105E2A	Dehydrogenase
A4A60_14100	ENOG4105VUF	Transcriptional regulator
A4A60_14110	ENOG4105DQ4	alcohol dehydrogenase
A4A60_14115	ENOG4108Z0Z	intracellular protease Pfpi family
A4A60_14120	ENOG4108HKT	sucrose-6-phosphate hydrolase
A4A60_14125	ENOG4105F3R	pts system mannose fructose sorbose family iid
A4A60_14130	ENOG4105ETZ	PTS System
A4A60_14135	ENOG4108IQ3	PTS system
A4A60_14140	ENOG4105YHU	PTS system
A4A60_14145	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A4A60_14150	ENOG4105C85	amino acid
A4A60_14155	ENOG4105N14	lysine exporter protein LysE YggA
A4A60_14160	ENOG4108NGU	Transcriptional regulator
A4A60_14165	ENOG4105JVQ	RNA Polymerase
A4A60_14170	ENOG4108P49	AntiSigma factor
A4A60_14180	ENOG4105WDR	
A4A60_14185	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A4A60_14190	ENOG41082JN	Transcriptional regulator
A4A60_14205	ENOG4105TMB	Formate nitrite transporter
A4A60_14210	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
A4A60_14215	ENOG4108JB9	formate dehydrogenase
A4A60_14230	ENOG4105C28	cystathionine
A4A60_14245	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
A4A60_14260	ENOG4107XRG	penicillin-binding protein
A4A60_14265	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A4A60_14270	ENOG4105DBI	uridine monophosphokinase
A4A60_14275	ENOG4105CFP	Peptidase U32
A4A60_14280	ENOG4105XYU	peptidase (U32 family)
A4A60_14285	ENOG4108VQJ	O-methyltransferase
A4A60_14290	ENOG4105HHA	aminodeoxychorismate lyase
A4A60_14295	ENOG4105VPH	UPF0473 protein
A4A60_14300	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A4A60_14305	ENOG4105VBH	UPF0297 protein
A4A60_14310	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A4A60_14315	ENOG4105C02	permease
A4A60_14320	ENOG4105CDA	abc transporter atp-binding protein
A4A60_14325	ENOG4105CT1	(ABC) transporter
A4A60_14330	ENOG4105EAD	ABC transporter
A4A60_14335	ENOG4105DRP	amino acid AbC transporter
A4A60_14350	ENOG41060CR	
A4A60_14360	ENOG4105C7H	Helicase, RecD TraA family
A4A60_14370	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A4A60_14375	ENOG4105C3J	Cysteine desulfurase
A4A60_14385	ENOG4105D1H	recombination factor protein RarA
A4A60_14390	ENOG4105CUZ	uba thif-type nad fad binding protein
A4A60_14400	ENOG4105C9M	aspartyl-trna synthetase
A4A60_14405	ENOG4105CUT	histidyl-tRNA synthetase
A4A60_14415	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A4A60_14425	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A4A60_14430	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A4A60_14435	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A4A60_14440	ENOG41067VP	Protein of unknown function (DUF1049)
A4A60_14445	ENOG4105NCW	Trka-c domain protein
A4A60_14450	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A4A60_14460	ENOG4105CKP	Polysaccharide Biosynthesis Protein
A4A60_14465	ENOG4108QG2	Membrane
A4A60_14470	ENOG4105NAP	
A4A60_14475	ENOG4105VIE	preprotein translocase, subunit YajC
A4A60_14480	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A4A60_14485	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
A4A60_14490	ENOG41061AI	Protein of unknown function (DUF2905)
A4A60_14495	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A4A60_14500	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A4A60_14510	ENOG4105IE8	Alpha-ketoglutarate permease
A4A60_14515	ENOG4105CK5	oxidoreductase
A4A60_14540	ENOG4105BZG	amino acid carrier protein
A4A60_14545	ENOG4105CDY	transcriptional regulatory protein
A4A60_14555	ENOG4106678	morphogenetic protein associated with SpoVID
A4A60_14560	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A4A60_14565	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A4A60_14570	ENOG4108IYU	L-aspartate oxidase
A4A60_14585	ENOG4105CQC	Prephenate dehydratase
A4A60_14590	ENOG41090I5	UPF0735 ACT domain-containing protein
A4A60_14595	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A4A60_14610	ENOG4105K46	50S ribosomal protein l27
A4A60_14615	ENOG4105X36	(ribosomal) protein
A4A60_14620	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A4A60_14635	ENOG4107QMS	site-determining protein
A4A60_14640	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
A4A60_14645	ENOG4105YHC	Rod shape-determining protein MreD
A4A60_14650	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A4A60_14655	ENOG4105DFF	Rod shape-determining protein mreb
A4A60_14660	ENOG4105W5Q	DNA repair protein (RadC
A4A60_14665	ENOG4108Z03	MAF-like protein
A4A60_14675	ENOG4106A3R	peptidase
A4A60_14680	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A4A60_14685	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A4A60_14695	ENOG4106AR7	Spore coat protein
A4A60_14700	ENOG41068KH	stage VI sporulation protein D
A4A60_14705	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A4A60_14710	ENOG4105D52	delta-aminolevulinic acid dehydratase
A4A60_14720	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A4A60_14730	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A4A60_14740	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A4A60_14745	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A4A60_14750	ENOG4108IUQ	atp-dependent protease
A4A60_14755	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A4A60_14760	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A4A60_14770	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A4A60_14775	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A4A60_14780	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A4A60_14785	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A4A60_14790	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A4A60_14795	ENOG4108ZP8	Acetolactate synthase small subunit
A4A60_14800	ENOG4105C7K	acetolactate synthase
A4A60_14820	ENOG4107KM7	Heat induced stress protein YflT
A4A60_14830	ENOG4105DQ6	Transposase
A4A60_14855	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
A4A60_14880	ENOG4105M59	Phosphodiesterase, mj0936 family
A4A60_14885	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A4A60_14890	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A4A60_14895	ENOG4108XJQ	germination protein
A4A60_14900	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A4A60_14905	ENOG41067TZ	transcriptional regulator, MarR family
A4A60_14910	ENOG4105PFC	Transcriptional regulator
A4A60_14920	ENOG4105E33	succinate dehydrogenase
A4A60_14930	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
A4A60_14945	ENOG4105CFH	Aspartokinase
A4A60_14950	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A4A60_14955	ENOG4105K63	Thioredoxin
A4A60_14960	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
A4A60_14965	ENOG4105C10	Electron transfer flavoprotein
A4A60_14970	ENOG4105BZJ	Electron transfer flavoprotein
A4A60_14975	ENOG41060WC	Enoyl-CoA hydratase
A4A60_14980	ENOG4107Z3H	Transcriptional regulator, TetR family
A4A60_14985	ENOG4105CEY	Amp-dependent synthetase and ligase
A4A60_14995	ENOG4105C98	muts2 protein
A4A60_15000	ENOG4105DCG	PHP domain protein
A4A60_15015	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A4A60_15020	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A4A60_15025	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A4A60_15035	ENOG4108RWN	rrna methyltransferase
A4A60_15040	ENOG41067MF	small acid-soluble spore protein
A4A60_15050	ENOG4105CQB	FAD linked oxidase domain protein
A4A60_15055	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A4A60_15070	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
A4A60_15075	ENOG4105DRS	transport system, permease
A4A60_15090	ENOG4108MDK	Dehydrogenase
A4A60_15100	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
A4A60_15105	ENOG4105EF1	ribulokinase
A4A60_15115	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
A4A60_15120	ENOG4105CN9	Peptidase m42 family protein
A4A60_15130	ENOG410696E	Membrane
A4A60_15135	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A4A60_15140	ENOG4105VJV	50s ribosomal protein L35
A4A60_15145	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
A4A60_15155	ENOG41067MG	lrgb family
A4A60_15165	ENOG4105DY9	regulatoR
A4A60_15170	ENOG4108HRK	Histidine kinase
A4A60_15175	ENOG4105U0R	haloacid dehalogenase-like hydrolase
A4A60_15180	ENOG4105C22	threonyL-tRNA synthetase
A4A60_15185	ENOG4108TDW	sporulation protein YtxC
A4A60_15205	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A4A60_15210	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A4A60_15215	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A4A60_15220	ENOG4105KVH	Transcriptional regulator
A4A60_15225	ENOG4105F27	Major Facilitator
A4A60_15230	ENOG4105CV8	reductase
A4A60_15235	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A4A60_15250	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A4A60_15255	ENOG4105C2M	dna polymerase I
A4A60_15260	ENOG4105BZU	Histidine kinase
A4A60_15265	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A4A60_15270	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A4A60_15275	ENOG4108HMX	isocitrate dehydrogenase (NADP)
A4A60_15280	ENOG4105BZN	citrate synthase
A4A60_15295	ENOG4108REF	Sporulation integral membrane protein ytvi
A4A60_15300	ENOG4105FS0	cytoplasmic membrane protein
A4A60_15305	ENOG4105CA9	Pyruvate kinase
A4A60_15310	ENOG4105CTQ	phosphohexokinase
A4A60_15320	ENOG4108IEY	Carboxyl transferase domain
A4A60_15325	ENOG4105C6K	Malic enzyme
A4A60_15330	ENOG4105C0B	DNA polymerase III (alpha subunit)
A4A60_15335	ENOG4105VV2	
A4A60_15345	ENOG4106EVM	
A4A60_15350	ENOG4105SFS	phosphoesterase RecJ domain protein
A4A60_15365	ENOG4105E8R	UPF0173 metal-dependent hydrolase
A4A60_15380	ENOG4105CH7	arginosuccinase
A4A60_15385	ENOG4105CDH	Citrulline--aspartate ligase
A4A60_15390	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
A4A60_15395	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A4A60_15410	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
A4A60_15415	ENOG4105KBJ	sporulation protein ytfj
A4A60_15425	ENOG4105VK3	rdd domain containing protein
A4A60_15430	ENOG4105D07	Signal peptide peptidase, SppA
A4A60_15435	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A4A60_15445	ENOG4105EFZ	amidohydrolase
A4A60_15450	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A4A60_15485	ENOG4105U5Y	Transcriptional regulator
A4A60_15495	ENOG4105BZU	Histidine kinase
A4A60_15500	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A4A60_15510	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A4A60_15520	ENOG4105F1V	Acetoin utilization protein
A4A60_15525	ENOG4105W87	Cbs domain
A4A60_15530	ENOG4105DGU	Histone deacetylase
A4A60_15535	ENOG4105ER2	Ompa motb domain protein
A4A60_15540	ENOG4107R0U	MotA TolQ exbB proton channel
A4A60_15545	ENOG4105ETE	Transcriptional regulator (LacI family
A4A60_15550	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
A4A60_15570	ENOG4105DFU	Cell wall formation (By similarity)
A4A60_15580	ENOG4108VDD	TRNA binding domain protein
A4A60_15610	ENOG4105C6K	Malic enzyme
A4A60_15615	ENOG4105C8F	Beta-lactamase domain protein
A4A60_15620	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A4A60_15630	ENOG4108V15	phosphotransferase enzyme family
A4A60_15635	ENOG4108IUM	Glycogen debranching enzyme
A4A60_15650	ENOG4107F58	2'-5' rna ligase
A4A60_15655	ENOG4105C6T	cysteine synthase
A4A60_15660	ENOG4107QSE	Dipeptidase
A4A60_15665	ENOG4105C7N	Xanthine uracil vitamin C permease
A4A60_15680	ENOG4105YW5	deoR family transcriptional regulator
A4A60_15695	ENOG4105CBX	hi0933 family
A4A60_15700	ENOG4105C94	Transporter
A4A60_15725	ENOG4105F5H	Glycosyl Hydrolase Family 88
A4A60_15745	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
A4A60_15755	ENOG4106A3M	Cytochrome p-450
A4A60_15760	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A4A60_15770	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A4A60_15775	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A4A60_15780	ENOG4108W8G	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity)
A4A60_15785	ENOG4105NTD	Inherit from COG: Hydrolase
A4A60_15800	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
A4A60_15805	ENOG4105I1K	ABC transporter
A4A60_15815	ENOG41085GJ	domain protein
A4A60_15820	ENOG4105C8T	Leucyl-tRNA synthetase
A4A60_15830	ENOG4105BZU	Histidine kinase
A4A60_15835	ENOG410605W	Major Facilitator
A4A60_15855	ENOG4105C19	ABC transporter
A4A60_15860	ENOG4105EWM	Histidine kinase
A4A60_15870	ENOG4107R34	abc transporter permease protein
A4A60_15875	ENOG4105C19	ABC transporter
A4A60_15890	ENOG4105DVE	abc transporter atp-binding protein
A4A60_15895	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
A4A60_15910	ENOG4105N5T	Radical SAM Protein
A4A60_15925	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
A4A60_15930	ENOG4108Z0R	Transferase
A4A60_15935	ENOG4105C85	amino acid
A4A60_15940	ENOG4105CAQ	asparagine synthetase
A4A60_15945	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A4A60_15950	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A4A60_15965	ENOG4105D2X	ABC transporter substrate-binding protein
A4A60_15975	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
A4A60_15990	ENOG4108RMU	ferritin dps family protein
A4A60_16005	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
A4A60_16010	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
A4A60_16015	ENOG4108V2W	Carbonate dehydratase
A4A60_16040	ENOG4105CC5	ABC transporter
A4A60_16045	ENOG4105CC5	ABC transporter
A4A60_16050	ENOG4105DIK	(ABC) transporter
A4A60_16055	ENOG4105DSE	periplasmic solute binding protein
A4A60_16060	ENOG4105DTQ	mandelate racemase muconate lactonizing
A4A60_16065	ENOG4105CEY	Amp-dependent synthetase and ligase
A4A60_16070	ENOG4108IPT	Naphthoate synthase
A4A60_16075	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
A4A60_16080	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
A4A60_16085	ENOG4105E4F	Isochorismate synthase
A4A60_16105	ENOG4108IAJ	Nad-dependent epimerase dehydratase
A4A60_16110	ENOG4107SBE	Glycosyl transferase (Group 1
A4A60_16125	ENOG4107SBE	Glycosyl transferase (Group 1
A4A60_16130	ENOG4108KS4	Spore coat protein
A4A60_16145	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A4A60_16155	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A4A60_16290	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
A4A60_16295	ENOG4105VRR	gCN5-related N-acetyltransferase
A4A60_16300	ENOG4105DZ6	Band 7 protein
A4A60_16310	ENOG4106DF1	
A4A60_16320	ENOG4108VNY	MOSC domain protein
A4A60_16325	ENOG4108JB8	alcohol dehydrogenase
A4A60_16330	ENOG4105C26	Dehydrogenase
A4A60_16335	ENOG4105TRT	Transcriptional regulator
A4A60_16350	ENOG4105CZN	Potassium uptake protein
A4A60_16355	ENOG4107I77	yiaA/B two helix domain
A4A60_16360	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
A4A60_16380	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A4A60_16390	ENOG4105EE0	oxidoreductase
A4A60_16395	ENOG4105DKG	l-rhamnose isomerase
A4A60_16400	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
A4A60_16405	ENOG4105DET	Rhamnulokinase
A4A60_16410	ENOG4105E98	transcriptional regulator DeoR family
A4A60_16430	ENOG4105C8Q	Methyl-accepting chemotaxis
A4A60_16435	ENOG4105C8Q	Methyl-accepting chemotaxis
A4A60_16440	ENOG4105C8Q	Methyl-accepting chemotaxis
A4A60_16465	ENOG4105C37	(CBS) domain
A4A60_16480	ENOG4107PBV	potassium channel
A4A60_16485	ENOG4107PBV	potassium channel
A4A60_16500	ENOG4107QYV	phosphohexose isomerase
A4A60_16510	ENOG4107QW4	alcohol dehydrogenase
A4A60_16515	ENOG4105WG9	Conserved Protein
A4A60_16525	ENOG4105CHM	Aminotransferase
A4A60_16530	ENOG4108ZB6	transcriptional regulator AsnC family
A4A60_16535	ENOG4108MUZ	hydrolase
A4A60_16545	ENOG4105C87	Aminotransferase class I and II
A4A60_16550	ENOG4108HGU	Histidine kinase
A4A60_16555	ENOG4105Y38	Kinase-associated protein B
A4A60_16575	ENOG4105BZ4	penicillin-binding protein
A4A60_16580	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
A4A60_16595	ENOG4108MRH	transcriptional regulatory protein
A4A60_16600	ENOG4105DIH	basic membrane
A4A60_16605	ENOG4108JQ9	ABC transporter
A4A60_16610	ENOG4105UIB	(ABC) transporter
A4A60_16630	ENOG4105D65	subunit l
A4A60_16635	ENOG4105HC0	Na H antiporter
A4A60_16640	ENOG4108ZE9	Monovalent cation H antiporter subunit C
A4A60_16645	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A4A60_16650	ENOG4105SC1	monovalent cation H antiporter subunit E
A4A60_16660	ENOG4105KJM	monovalent cation h antiporter subunit g
A4A60_16665	ENOG4105KA0	thioesterase Superfamily protein
A4A60_16675	ENOG4105BZU	Histidine kinase
A4A60_16700	ENOG4105D58	Diguanylate phosphodiesterase
A4A60_16705	ENOG4105DAP	Nicotinate phosphoribosyltransferase
A4A60_16730	ENOG4105C02	permease
A4A60_16750	ENOG410904N	short-chain dehydrogenase reductase
A4A60_16785	ENOG4108K8K	Transcriptional regulator
A4A60_16790	ENOG4105DCF	alanine dehydrogenase
A4A60_16800	ENOG4105WQT	MbtH domain protein
A4A60_16805	ENOG4105CEY	Amp-dependent synthetase and ligase
A4A60_16810	ENOG4105WQI	isochorismatase
A4A60_16815	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
A4A60_16820	ENOG4105E4F	Isochorismate synthase
A4A60_16825	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
A4A60_16830	ENOG4105NIV	Esterase
A4A60_16850	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A4A60_16860	ENOG41069ER	domain protein
A4A60_16875	ENOG4105CEP	NADH dehydrogenase
A4A60_16880	ENOG4105CAY	ferredoxin--nadp reductase
A4A60_16905	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A4A60_16925	ENOG4105ZKE	UPF0349 protein
A4A60_16940	ENOG41083MR	nifu domain-containing protein
A4A60_16945	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A4A60_16950	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
A4A60_16955	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A4A60_16960	ENOG4105D6E	homoserine dehydrogenase
A4A60_16970	ENOG4108W5N	phosphatidylglycerophosphatase a
A4A60_16975	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
A4A60_16985	ENOG4105MMD	transcriptional regulator
A4A60_16990	ENOG4106EGE	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
A4A60_16995	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A4A60_17000	ENOG4105FAA	peptidase M23
A4A60_17005	ENOG4108YTE	sporulation protein YunB
A4A60_17010	ENOG4105KZD	Domain of unknown function (DUF1805)
A4A60_17015	ENOG4107R8B	5'-nucleotidase
A4A60_17025	ENOG4105I3N	Conserved Protein
A4A60_17035	ENOG4105CD3	dihydroorotase
A4A60_17040	ENOG4105G9B	Transcriptional regulator
A4A60_17055	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
A4A60_17060	ENOG4105VT2	5-hydroxyisourate hydrolase
A4A60_17075	ENOG4107YV9	domain protein
A4A60_17080	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
A4A60_17095	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
A4A60_17100	ENOG4105C5R	Aminotransferase
A4A60_17115	ENOG4108K8S	endonuclease I
A4A60_17120	ENOG4108IJ9	(ABC) transporter
A4A60_17125	ENOG4105FDP	GntR family transcriptional regulator
A4A60_17130	ENOG4108KPW	sugar kinase
A4A60_17140	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
A4A60_17145	ENOG4105XN3	extracellular solute-binding protein family 1
A4A60_17150	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
A4A60_17155	ENOG4105PKS	Excinuclease abc c subunit domain protein
A4A60_17160	ENOG4107VFR	oxidoreductase
A4A60_17175	ENOG4105DQ6	Transposase
A4A60_17185	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4A60_17190	ENOG4105NPE	arsR family transcriptional regulator
A4A60_17200	ENOG4106BHF	
A4A60_17205	ENOG4106ANW	SMI1_KNR4
A4A60_17210	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
A4A60_17225	ENOG41068G1	
A4A60_17245	ENOG4108FKH	Transglycosylase SLT domain
A4A60_17445	ENOG4105DIW	FeS assembly protein SUFB
A4A60_17450	ENOG4108UNV	SUF system FeS assembly protein, NifU family
A4A60_17455	ENOG4105C9B	Cysteine desulfurase
A4A60_17460	ENOG4105JRK	feS assembly protein SufD
A4A60_17465	ENOG4105C3K	feS assembly ATPase SufC
A4A60_17480	ENOG4105D01	(LipO)protein
A4A60_17485	ENOG4108UMI	ABC transporter, permease
A4A60_17490	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A4A60_17515	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A4A60_17520	ENOG41080E8	Transcriptional regulator, Spx MgsR family
A4A60_17525	ENOG4105C1G	acyl-Coa dehydrogenase
A4A60_17530	ENOG4105CHU	acetyl-coa acetyltransferase
A4A60_17560	ENOG41067TZ	transcriptional regulator, MarR family
A4A60_17565	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A4A60_17570	ENOG4105MDS	4-oxalocrotonate tautomerase
A4A60_17580	ENOG4105EGI	Transcriptional regulator
A4A60_17590	ENOG4105E0A	ABC, transporter
A4A60_17660	ENOG4105HUF	DNA protection during starvation protein
A4A60_17670	ENOG4105C0H	protease
A4A60_17680	ENOG4105F3H	Histidine kinase
A4A60_17690	ENOG41067SE	Tetr family transcriptional regulator
A4A60_17695	ENOG4105C9Q	fumarate hydratase class II
A4A60_17720	ENOG4105WH1	Two component transcriptional regulator luxr family
A4A60_17725	ENOG4105ENE	Histidine kinase
A4A60_17740	ENOG41087YS	Phage shock protein A
A4A60_17755	ENOG4108WBT	adenosyltransferase
A4A60_17760	ENOG4105E0A	ABC, transporter
A4A60_17765	ENOG4105EHG	Permease protein
A4A60_17770	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A4A60_17775	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
A4A60_17780	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
A4A60_17790	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A4A60_17800	ENOG4106DF4	Sigma-70, region 4
A4A60_17810	ENOG4105F0F	Oxalate decarboxylase
A4A60_17820	ENOG4107RBB	ABC transporter, permease
A4A60_17825	ENOG4105C19	ABC transporter
A4A60_17830	ENOG4108WMK	Efflux transporter RND family MFP subunit
A4A60_17835	ENOG4105E0A	ABC, transporter
A4A60_17840	ENOG4105EHG	Permease protein
A4A60_17845	ENOG4105DQ5	transport system permease protein
A4A60_17860	ENOG4105D5Q	Arginine ornithine antiporter
A4A60_17870	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
A4A60_17875	ENOG4107QZ2	Sulfatase
A4A60_17880	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
A4A60_17885	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A4A60_17890	ENOG4105E0C	molybdate abc transporter
A4A60_17905	ENOG4105EEQ	Na H antiporter
A4A60_17910	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
A4A60_17915	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A4A60_17920	ENOG4105EEM	helicase
A4A60_17930	ENOG4105EN6	Membrane
A4A60_17940	ENOG4107ZQN	disulfide bond
A4A60_17945	ENOG4105C59	p-type ATPase
A4A60_17955	ENOG4105C59	p-type ATPase
A4A60_17960	ENOG410681U	heavy metal transport detoxification protein
A4A60_17965	ENOG4105VPX	protein, conserved in bacteria
A4A60_17970	ENOG4105D9R	oxidoreductase
A4A60_17980	ENOG4105ME7	Membrane
A4A60_17985	ENOG4105RXJ	
A4A60_17990	ENOG4105KPY	Small multidrug resistance protein
A4A60_17995	ENOG4105KBX	Transcriptional regulator, TetR family
A4A60_18000	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
A4A60_18025	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
A4A60_18040	ENOG41068G1	
A4A60_18050	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
A4A60_18270	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A4A60_18275	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A4A60_18285	ENOG4105XZU	Preprotein translocase, subunit SecG
A4A60_18310	ENOG4105KVH	Transcriptional regulator
A4A60_18315	ENOG4105C8Q	Methyl-accepting chemotaxis
A4A60_18320	ENOG4105R40	Glycine betaine carnitine choline
A4A60_18325	ENOG4108HQR	Glycine betaine
A4A60_18330	ENOG4105E90	ABC transporter
A4A60_18335	ENOG4108IJ8	ABC transporter
A4A60_18340	ENOG4107HG4	Transcriptional regulator
A4A60_18345	ENOG4105R40	Glycine betaine carnitine choline
A4A60_18350	ENOG4108HQR	Glycine betaine
A4A60_18355	ENOG4105E90	ABC transporter
A4A60_18360	ENOG4108IJ8	ABC transporter
A4A60_18365	ENOG4107HG4	Transcriptional regulator
A4A60_18370	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A4A60_18375	ENOG4108QCI	YvbH-like oligomerisation region
A4A60_18385	ENOG4105T65	Membrane-associated protein
A4A60_18390	ENOG4108W0I	acetyltransferase
A4A60_18395	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A4A60_18400	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A4A60_18405	ENOG4105CP7	Triose-phosphate isomerase
A4A60_18410	ENOG4105BZA	Phosphoglycerate kinase
A4A60_18420	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A4A60_18435	ENOG4105CMD	Transcriptional regulator, GntR family
A4A60_18440	ENOG4105DEN	Luciferase family
A4A60_18445	ENOG4105GZI	Transcriptional regulator
A4A60_18450	ENOG4107RT3	EamA-like transporter family
A4A60_18465	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
A4A60_18470	ENOG4107QR9	Iron-sulfur cluster binding protein
A4A60_18475	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A4A60_18495	ENOG4105BZU	Histidine kinase
A4A60_18500	ENOG4105KCT	ABC transporter
A4A60_18505	ENOG4108M15	ABC transporter
A4A60_18510	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
A4A60_18515	ENOG4108MJI	response regulator
A4A60_18530	ENOG4105EG2	ABC transporter, permease
A4A60_18540	ENOG4107FKK	extracellular solute-binding protein family 1
A4A60_18550	ENOG4105JXH	GntR family transcriptional regulator
A4A60_18555	ENOG4105DAA	L-lactate
A4A60_18570	ENOG4108ZPC	Polysaccharide pyruvyl transferase
A4A60_18575	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A4A60_18580	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
A4A60_18585	ENOG4105D3Q	Sugar transferase
A4A60_18595	ENOG4105K64	Glycosyl transferase, family 2
A4A60_18605	ENOG4107QRS	glycosyltransferase group 2 family protein
A4A60_18610	ENOG41068W6	Capsular polysaccharide biosynthesis protein
A4A60_18615	ENOG4108KMV	Glycosyl transferase (Group 1
A4A60_18620	ENOG4105K64	Glycosyl transferase, family 2
A4A60_18625	ENOG4108PQP	glycosyl transferase group 1
A4A60_18635	ENOG4108QV3	biosynthesis protein
A4A60_18640	ENOG4105HTX	biosynthesis protein
A4A60_18650	ENOG4105EBR	Carboxylesterase
A4A60_18660	ENOG4105PY6	Phenolic acid decarboxylase
A4A60_18665	ENOG4105NI3	Protein of unknown function (DUF3237)
A4A60_18680	ENOG4105EDQ	levansucrase EC 2.4.1.10
A4A60_18685	ENOG4108HKT	sucrose-6-phosphate hydrolase
A4A60_18690	ENOG4107QTZ	amino acid
A4A60_18720	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A4A60_18725	ENOG4107URF	beta-phospho-glucomutase
A4A60_18730	ENOG4105CG3	alpha amylase, catalytic region
A4A60_18745	ENOG4105EG2	ABC transporter, permease
A4A60_18750	ENOG4105D56	permease protein
A4A60_18755	ENOG4107FKK	extracellular solute-binding protein family 1
A4A60_18760	ENOG4108IUK	alpha amylase, catalytic
A4A60_18765	ENOG4105FKQ	transcriptional regulator
A4A60_18770	ENOG4108URH	decarboxylase
A4A60_18775	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
A4A60_18780	ENOG4105CHH	sulfate transporter
A4A60_18785	ENOG4108V2W	Carbonate dehydratase
A4A60_18790	ENOG4105C5I	Dehydrogenase
A4A60_18800	ENOG4105C19	ABC transporter
A4A60_18805	ENOG4105EWM	Histidine kinase
A4A60_18820	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
A4A60_18825	ENOG4105KRI	phosphocarrier protein (HPr
A4A60_18830	ENOG4105CIE	May be required for sporulation (By similarity)
A4A60_18835	ENOG4105CHW	UPF0052 protein
A4A60_18840	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A4A60_18845	ENOG4108Z4K	mutator MutT protein
A4A60_18850	ENOG4105C3M	thioredoxin reductase
A4A60_18865	ENOG4105BZ1	(ABC) transporter
A4A60_18875	ENOG4106FGC	
A4A60_18885	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A4A60_18890	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A4A60_18895	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A4A60_18900	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A4A60_18905	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A4A60_18910	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A4A60_18915	ENOG4107RN8	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A4A60_18920	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
A4A60_18930	ENOG4108E16	pectate lyase
A4A60_18940	ENOG4105DQ6	Transposase
A4A60_18945	ENOG4108S4C	acetyltransferase
A4A60_18950	ENOG4107XGZ	Hydrolase
A4A60_18955	ENOG4105HKU	nucleoside recognition domain-containing protein
A4A60_18960	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A4A60_18965	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
A4A60_18970	ENOG4105CE4	GlcNAc 6-P deacetylase
A4A60_18975	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A4A60_18980	ENOG4105FDP	GntR family transcriptional regulator
A4A60_18985	ENOG41088CQ	domain protein
A4A60_19000	ENOG41086DT	Membrane protein of unknown function
A4A60_19005	ENOG41067S9	phage shock protein C, PspC
A4A60_19010	ENOG4108PY7	
A4A60_19025	ENOG4105I03	Flagellin
A4A60_19030	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A4A60_19035	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A4A60_19050	ENOG4105MKU	Transcriptional regulator
A4A60_19070	ENOG4105CN1	protease
A4A60_19075	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A4A60_19080	ENOG4105CAK	Cell division ATP-binding protein ftsE
A4A60_19095	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A4A60_19110	ENOG4105DQ6	Transposase
A4A60_19115	ENOG4105MS2	ribosomal subunit Interface protein
A4A60_19130	ENOG4105MQ3	flagellar protein FliS
A4A60_19135	ENOG4107RT6	flagellar hook-associated
A4A60_19140	ENOG41083S7	flagellar protein FlaG
A4A60_19145	ENOG4105I03	Flagellin
A4A60_19150	ENOG41085Y9	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
A4A60_19155	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
A4A60_19160	ENOG4105MKD	
A4A60_19165	ENOG4105DTJ	flagellar hook-associated protein
A4A60_19170	ENOG4105E1Q	flagellar hook-associated protein
A4A60_19185	ENOG4105RU3	
A4A60_19190	ENOG41081UC	Inherit from COG: Competence protein
A4A60_19210	ENOG4105WH1	Two component transcriptional regulator luxr family
A4A60_19215	ENOG4105BZU	Histidine kinase
A4A60_19220	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A4A60_19225	ENOG4108KGH	TRANSCRIPTIONal
A4A60_19260	ENOG4108RDQ	ABC transporter
A4A60_19270	ENOG4105ESV	Glycosyl transferase, family 4
A4A60_19275	ENOG4107EF8	Glycosyl transferase (Group 1
A4A60_19290	ENOG4105QZI	O-Antigen Polymerase
A4A60_19295	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A4A60_19300	ENOG4107RA4	Glycosyl transferase (Group 1
A4A60_19305	ENOG4105PSV	Polysaccharide Biosynthesis Protein
A4A60_19310	ENOG4105D3Q	Sugar transferase
A4A60_19320	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A4A60_19325	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A4A60_19335	ENOG4105EY8	ABC transporter
A4A60_19355	ENOG4107SJB	teichoic acid biosynthesis
A4A60_19360	ENOG4107SJB	teichoic acid biosynthesis
A4A60_19365	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
A4A60_19375	ENOG4107RZX	Teichoic acid biosynthesis protein
A4A60_19385	ENOG4105DG6	mannose-6-phosphate isomerase
A4A60_19405	ENOG4108NHD	germination protein
A4A60_19415	ENOG4108KGH	TRANSCRIPTIONal
A4A60_19420	ENOG4105J7I	hydrolase
A4A60_19425	ENOG4105K4H	Nlp p60 protein
A4A60_19440	ENOG4105PNM	synthesis protein
A4A60_19450	ENOG4105N98	Capsule biosynthesis protein capB
A4A60_19460	ENOG4105ETE	Transcriptional regulator (LacI family
A4A60_19465	ENOG4108RVA	ribokinase
A4A60_19470	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
A4A60_19475	ENOG4105C2J	ABC transporter
A4A60_19480	ENOG4105CNN	ABC, transporter
A4A60_19485	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A4A60_19500	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A4A60_19505	ENOG4107FQX	Alpha-acetolactate decarboxylase
A4A60_19515	ENOG4107RSM	transcriptional regulator
A4A60_19530	ENOG4106UIA	
A4A60_19530	ENOG4106UIA	
A4A60_19545	ENOG4107XC4	flavin reductase domain protein, FMN-binding
A4A60_19555	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A4A60_19565	ENOG4105CAH	Chromate
A4A60_19570	ENOG4105FGV	Chromate
A4A60_19580	ENOG4108WS4	fmn reductase
A4A60_19585	ENOG4107V2S	Transcriptional regulator
A4A60_19630	ENOG4108XI2	Domain of unknown function (DUF1963)
A4A60_19635	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A4A60_19640	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
A4A60_19645	ENOG4107YJ4	chain length determinant protein
A4A60_19650	ENOG4105HTX	biosynthesis protein
A4A60_19660	ENOG4105KBK	Zinc finger, swim domain protein
A4A60_19665	ENOG4105C0D	helicase
A4A60_19670	ENOG410667J	hydrolase
A4A60_19675	ENOG4105E98	transcriptional regulator DeoR family
A4A60_19680	ENOG4105Z8H	single-stranded DNA-binding protein
A4A60_19705	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A4A60_19710	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A4A60_19720	ENOG4105CGA	flagellar basal-body rod protein FlgG
A4A60_19730	ENOG4105DFF	Rod shape-determining protein mreb
A4A60_19735	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
A4A60_19740	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
A4A60_19745	ENOG4105CZM	Major Facilitator
A4A60_19750	ENOG4108M26	parallel beta-helix repeat protein
A4A60_19755	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
A4A60_19760	ENOG41080V3	Major Facilitator superfamily
A4A60_19765	ENOG4105D3W	isochorismatase
A4A60_19770	ENOG4107P26	
A4A60_19775	ENOG4105BZU	Histidine kinase
A4A60_19785	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
A4A60_19795	ENOG4105FRN	stage II sporulation protein
A4A60_19800	ENOG4107TCE	N-acetyltransferase
A4A60_19810	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
A4A60_19820	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A4A60_19825	ENOG4107TXC	Transcriptional regulator
A4A60_19830	ENOG4106BRK	
A4A60_19840	ENOG4108Z40	Transcriptional regulator
A4A60_19845	ENOG4105CQM	Urea amidohydrolase subunit alpha
A4A60_19850	ENOG4105KI2	Urea amidohydrolase subunit beta
A4A60_19855	ENOG4108YZ9	Urea amidohydrolase subunit gamma
A4A60_19885	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A4A60_19895	ENOG4108TF4	von Willebrand factor, type A
A4A60_19910	ENOG4105JFG	SpoIID LytB domain protein
A4A60_19915	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A4A60_19925	ENOG4106778	Protein of unknown function (DUF1146)
A4A60_19935	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A4A60_19940	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A4A60_19945	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A4A60_19950	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A4A60_19975	ENOG4107RB6	it plays a direct role in the translocation of protons across the membrane (By similarity)
A4A60_19985	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A4A60_19990	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A4A60_19995	ENOG4108UIC	UPF0340 protein
A4A60_20000	ENOG4108YZG	isomerase
A4A60_20005	ENOG4107WAU	Protein tyrosine phosphatase
A4A60_20010	ENOG410815N	Probably functions as a manganese efflux pump (By similarity)
A4A60_20015	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A4A60_20025	ENOG4108ZXQ	stage ii sporulation protein r
A4A60_20040	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A4A60_20045	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A4A60_20050	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
A4A60_20060	ENOG4107TT2	Auxin Efflux Carrier
A4A60_20065	ENOG4105C6K	Malic enzyme
A4A60_20070	ENOG4107104	thymidine kinase
A4A60_20075	ENOG41082DI	50s ribosomal protein l31
A4A60_20080	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A4A60_20090	ENOG4105CBT	Fructose-1,6-bisphosphatase
A4A60_20095	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A4A60_20100	ENOG4107XMI	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A4A60_20105	ENOG4105D2N	Aldolase
A4A60_20110	ENOG410812K	response regulator receiver protein
A4A60_20120	ENOG4105DQ6	Transposase
A4A60_20130	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A4A60_20140	ENOG4105C1G	acyl-Coa dehydrogenase
A4A60_20145	ENOG4105DF6	Fe-S oxidoreductase
A4A60_20155	ENOG4105E5J	UV damage endonuclease
A4A60_20175	ENOG4105C75	arginyL-tRNA synthetase
A4A60_20180	ENOG410684U	Domain of unknown function (DUF1934)
A4A60_20190	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
A4A60_20240	ENOG4107JM4	Tetratricopeptide repeat
A4A60_20255	ENOG4105CYW	agmatinase
A4A60_20260	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A4A60_20265	ENOG4105BZ4	penicillin-binding protein
A4A60_20275	ENOG4108XFG	YwhD family
A4A60_20280	ENOG4108Z4T	Peptidase M50
A4A60_20285	ENOG41069HH	4-oxalocrotonate tautomerase
A4A60_20290	ENOG41067TZ	transcriptional regulator, MarR family
A4A60_20295	ENOG4105C22	threonyL-tRNA synthetase
A4A60_20305	ENOG4105C57	major facilitator superfamily
A4A60_20310	ENOG41062ES	Transcriptional regulator
A4A60_20320	ENOG4105DCI	Phosphohydrolase
A4A60_20330	ENOG4108VCI	transcription factor, rsfa family
A4A60_20335	ENOG4108RNG	Permease of the drug metabolite transporter
A4A60_20340	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
A4A60_20345	ENOG4105DUM	transcriptional regulator, lysR family
A4A60_20350	ENOG4108IJ2	phosphate acetyltransferase
A4A60_20365	ENOG4105CHM	Aminotransferase
A4A60_20375	ENOG4108V3M	Inherit from COG: acetyl-CoA carboxylase biotin carboxylase
A4A60_20380	ENOG4105CHR	reductase
A4A60_20385	ENOG4106CHD	Bacilysin biosynthesis protein bacB
A4A60_20390	ENOG41061WN	bacilysin biosynthesis protein
A4A60_20395	ENOG4105FCW	Major Facilitator superfamily
A4A60_20410	ENOG4105C26	Dehydrogenase
A4A60_20415	ENOG4105D82	Glutamate dehydrogenase
A4A60_20425	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
A4A60_20430	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
A4A60_20435	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A4A60_20440	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
A4A60_20445	ENOG4107P9E	Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG
A4A60_20450	ENOG4107TY6	Acylneuraminate cytidylyltransferase
A4A60_20460	ENOG41067MN	Spore coat polysaccharide biosynthesis protein spsD
A4A60_20465	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A4A60_20505	ENOG4105C26	Dehydrogenase
A4A60_20510	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A4A60_20515	ENOG4108RJ9	Glycosyl transferase, family 2
A4A60_20520	ENOG4105DWF	phosphomethylpyrimidine kinase
A4A60_20535	ENOG4105C5Y	PTS System
A4A60_20540	ENOG4108QTI	)-transporter
A4A60_20555	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4A60_20560	ENOG4105DEN	Luciferase family
A4A60_20565	ENOG4108DBC	nitroreductase
A4A60_20585	ENOG41060D1	Quinol oxidase
A4A60_20590	ENOG4105CCU	oxidase (Subunit III)
A4A60_20595	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A4A60_20600	ENOG4105E2S	oxidase) subunit II
A4A60_20605	ENOG4107BMA	Transglycosylase associated protein
A4A60_20615	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A4A60_20620	ENOG4105WH5	Teichoic acid glycosylation protein
A4A60_20645	ENOG4107ZXU	DSBA oxidoreductase
A4A60_20650	ENOG4105DBE	peroxidase
A4A60_20655	ENOG410650H	(LipO)protein
A4A60_20660	ENOG4107SJW	iron permease, FTR1
A4A60_20665	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A4A60_20675	ENOG4105CMU	LysR family (Transcriptional regulator
A4A60_20680	ENOG4105VAW	lrga family
A4A60_20685	ENOG41067MG	lrgb family
A4A60_20690	ENOG4105D8G	Major Facilitator superfamily
A4A60_20700	ENOG4105DR4	Methyltransferase
A4A60_20710	ENOG4108YV3	Protein of unknown function (DUF2711)
A4A60_20715	ENOG4105CK1	PTS System
A4A60_20740	ENOG4105X1N	Glycosyl transferase family 8
A4A60_20750	ENOG4105GVJ	transcriptional regulator
A4A60_20755	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A4A60_20760	ENOG4105IIU	Aminopeptidase
A4A60_20775	ENOG4105DQ6	Transposase
A4A60_20780	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
A4A60_20795	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
A4A60_20800	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
A4A60_20810	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
A4A60_20820	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A4A60_20825	ENOG4105F8D	glycoside hydrolase family 4
A4A60_20830	ENOG4105VCP	PTS System
A4A60_20835	ENOG4105CK1	PTS System
A4A60_20840	ENOG4105VZJ	PTS System
A4A60_20845	ENOG4105EMD	TRANSCRIPTIONal
A4A60_20855	ENOG4108VX5	3-methyladenine DNA glycosylase
A4A60_20860	ENOG4105CH6	catalase
A4A60_20875	ENOG4105DA5	(ABC) transporter
A4A60_20880	ENOG41069JR	
A4A60_20900	ENOG4105ETS	cytosine purines uracil thiamine allantoin
A4A60_20905	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A4A60_20910	ENOG4108JJ8	(ABC) transporter
A4A60_20915	ENOG4108JJ9	ABC, transporter
A4A60_20920	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A4A60_20925	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A4A60_20930	ENOG4105D2K	citrate carrier protein
A4A60_20945	ENOG4107BJW	polysaccharide deacetylase
A4A60_20965	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
A4A60_20975	ENOG4105CMR	udp-glucose 4-epimerase
A4A60_20990	ENOG4105WH1	Two component transcriptional regulator luxr family
A4A60_20995	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A4A60_21025	ENOG4105DTD	Dehydrogenase
A4A60_21030	ENOG4108IIH	CoA-transferase subunit B
A4A60_21035	ENOG4105D6N	CoA-transferase, subunit a
A4A60_21040	ENOG4105CY2	Citrate transporter
A4A60_21050	ENOG4105DHI	Methyltransferase
A4A60_21070	ENOG4105CH6	catalase
A4A60_21075	ENOG4105D4T	Citrate transporter
A4A60_21080	ENOG4108RZ2	Glycoside hydrolase family 16
A4A60_21085	ENOG4105CID	antiterminator
A4A60_21095	ENOG4105DEU	major facilitator superfamily
A4A60_21100	ENOG4105C1J	atp-dependent rna helicase
A4A60_21105	ENOG4107TDE	lipolytic protein G-D-S-L family
A4A60_21225	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
A4A60_21235	ENOG4107YZX	Universal stress protein
A4A60_21255	ENOG4107EV6	Inherit from COG: YD repeat protein
A4A60_21270	ENOG4108F3G	Type I restriction-modification system, R subunit
A4A60_21275	ENOG4105M6F	mutator MutT protein
A4A60_21285	ENOG4106Z5D	Glycoside Hydrolase Family 43
A4A60_21290	ENOG4105CGP	Urocanate hydratase
A4A60_21300	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A4A60_21305	ENOG4105D9N	nucleoside
A4A60_21315	ENOG4107RHR	regulatoR
A4A60_21320	ENOG4108TM9	integral membrane protein
A4A60_21325	ENOG4105ENY	Ethanolamine utilization protein eutH
A4A60_21330	ENOG4108PGP	mmge prpd family protein
A4A60_21335	ENOG4105CH2	amidohydrolase
A4A60_21345	ENOG4108HW4	amino acid AbC transporter
A4A60_21350	ENOG4105EAB	amino acid AbC transporter
A4A60_21355	ENOG4108XSB	acetyltransferase, (GNAT) family
A4A60_21360	ENOG4105CPU	Monooxygenase
A4A60_21365	ENOG4107QHE	Choloylglycine hydrolase
A4A60_21370	ENOG410667J	hydrolase
A4A60_21400	ENOG4108V5C	ABC transporter
A4A60_21430	ENOG4105D2N	Aldolase
A4A60_21435	ENOG4107TRN	Xylose isomerase domain protein TIM barrel
A4A60_21440	ENOG4105F0H	myo-inositol catabolism protein
A4A60_21445	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
A4A60_21455	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
A4A60_21460	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
A4A60_21465	ENOG4105D7K	pfkb domain protein
A4A60_21485	ENOG4105CPC	Aldo Keto reductase
A4A60_21515	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A4A60_21530	ENOG4105ST3	Transcriptional regulator
A4A60_21535	ENOG4105C26	Dehydrogenase
A4A60_21540	ENOG41085PJ	rdd domain containing protein
A4A60_21550	ENOG41085PJ	rdd domain containing protein
A4A60_21565	ENOG4105J7D	transcriptional regulator
A4A60_21570	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
A4A60_21575	ENOG41061AU	MarR family Transcriptional regulator
A4A60_21585	ENOG41067MG	lrgb family
A4A60_21595	ENOG4105BZW	Glycerate kinase
A4A60_21600	ENOG4105G3Z	GntR family transcriptional regulator
A4A60_21605	ENOG4105CMG	Carbohydrate kinase
A4A60_21610	ENOG4105C6Z	Gluconate
A4A60_21615	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A4A60_21620	ENOG4105D3R	alkyl hydroperoxide reductase
A4A60_21625	ENOG4108JU3	Alkyl hydroperoxide reductase
A4A60_21630	ENOG4105CS2	ec 3.2.1.21
A4A60_21640	ENOG4108S3Y	transcriptional regulator
A4A60_21645	ENOG4106KKU	
A4A60_21650	ENOG4108Z15	abc transporter atp-binding protein
A4A60_21655	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
A4A60_21670	ENOG4105VN1	Heat shock protein
A4A60_21680	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
A4A60_21685	ENOG4106QJ6	Integrase catalytic subunit
A4A60_21700	ENOG4105ENA	helicase
A4A60_21750	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A4A60_21760	ENOG4105E2A	Dehydrogenase
A4A60_21780	ENOG4105NUN	Orthopoxvirus protein of unknown function (DUF830)
A4A60_21785	ENOG4105WQG	acetyltransferase
A4A60_21800	ENOG41066UZ	arginase EC 3.5.3.1
A4A60_21805	ENOG4108IQI	permease
A4A60_21810	ENOG4105C8Y	Acetylornithine aminotransferase
A4A60_21835	ENOG41082BM	Transcriptional regulator, arsr family
A4A60_21840	ENOG4108JUB	Transcriptional regulator
A4A60_21850	ENOG4105C0H	protease
A4A60_21855	ENOG4105Q2H	domain protein
A4A60_21870	ENOG4105BZU	Histidine kinase
A4A60_21875	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4A60_21900	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A4A60_21905	ENOG4105HB7	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4A60_21910	ENOG4105CDU	Replicative dna helicase
A4A60_21935	ENOG4105DJ2	Major Facilitator Superfamily
A4A60_21940	ENOG4105EDW	glycosyl transferase, family 39
A4A60_21945	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A4A60_21950	ENOG4105BZR	domain protein
A4A60_21970	ENOG4105KVH	Transcriptional regulator
A4A60_21975	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
A4A60_21995	ENOG41090E6	transcriptional regulator MERR family
A4A60_22005	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
A4A60_22010	ENOG4105DDN	Pentapeptide repeat-containing protein
A4A60_22025	ENOG4108U05	Transcriptional regulator
A4A60_22030	ENOG41082BV	acetyltransferase
A4A60_22050	ENOG4105NAE	bifunctional deaminase-reductase domain protein
A4A60_22055	ENOG4105FTQ	Dna gyrase
A4A60_22060	ENOG4105C7Z	Conserved Protein
A4A60_22065	ENOG4107FCW	Abortive infection protein
A4A60_22075	ENOG4108UW5	maltose o-acetyltransferase
A4A60_22080	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4A60_22090	ENOG4105CGK	Exodeoxyribonuclease III
A4A60_22095	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A4A60_22100	ENOG4108UUM	single-stranded DNA-binding protein
A4A60_22105	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A4A60_22110	ENOG4105C3G	gtp-binding protein
A4A60_22115	ENOG4108J2R	molybdopterin oxidoreductase
A4A60_22120	ENOG4105VDK	protein, conserved in bacteria
A4A60_22130	ENOG4108ZDA	Sporulation protein YyaC
A4A60_22140	ENOG4105DQ6	Transposase
A4A60_22145	ENOG4105FA0	parb-like partition protein
A4A60_22150	ENOG4107QJE	Chromosome Partitioning Protein
A4A60_22165	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A4A60_22170	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A4A60_22175	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A4A60_22190	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)