locus-tag	class	description
BHE96_00010	COG0592	DNA-directed DNA polymerase activity
BHE96_00015	COG2501	S4 domain
BHE96_00030	COG0187	DNA topoisomerase II activity
BHE96_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BHE96_00070	COG0516	GMP reductase activity
BHE96_00070	COG0517	IMP dehydrogenase activity
BHE96_00075	COG1686	Belongs to the peptidase S11 family
BHE96_00095	COG1929	Belongs to the glycerate kinase type-1 family
BHE96_00105	COG1428	Deoxynucleoside kinase
BHE96_00110	COG1428	Deoxynucleoside kinase
BHE96_00115	COG3858	chitin binding
BHE96_00115	COG1388	LysM domain
BHE96_00120	COG1335	isochorismatase
BHE96_00125	COG0590	tRNA wobble adenosine to inosine editing
BHE96_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BHE96_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BHE96_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BHE96_00195	COG3853	Toxic anion resistance protein (TelA)
BHE96_00200	COG1982	Orn Lys Arg decarboxylase major
BHE96_00210	COG3870	Protein conserved in bacteria
BHE96_00215	COG1728	Protein conserved in bacteria
BHE96_00220	COG0470	DNA polymerase III
BHE96_00225	COG1774	PSP1 C-terminal conserved region
BHE96_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BHE96_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BHE96_00250	COG2002	toxin-antitoxin pair type II binding
BHE96_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHE96_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHE96_00260	COG0084	hydrolase, TatD family'
BHE96_00265	COG3584	3D domain protein
BHE96_00265	COG3583	domain protein
BHE96_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BHE96_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BHE96_00285	COG4466	Protein conserved in bacteria
BHE96_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BHE96_00305	COG0251	oxidation-reduction process
BHE96_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BHE96_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BHE96_00345	COG2002	toxin-antitoxin pair type II binding
BHE96_00350	COG2244	polysaccharide biosynthetic process
BHE96_00355	COG3956	TIGRFAM MazG family protein
BHE96_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BHE96_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BHE96_00380	COG1098	S1 RNA binding domain
BHE96_00395	COG2208	phosphoserine phosphatase activity
BHE96_00400	COG2304	oxidoreductase activity
BHE96_00405	COG0515	serine threonine protein kinase
BHE96_00410	COG0037	tRNA processing
BHE96_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BHE96_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BHE96_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BHE96_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHE96_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
BHE96_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BHE96_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BHE96_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BHE96_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BHE96_00475	COG1396	sequence-specific DNA binding
BHE96_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHE96_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BHE96_00565	COG4463	regulation of RNA biosynthetic process
BHE96_00570	COG3880	PFAM UvrB UvrC protein
BHE96_00580	COG0542	response to heat
BHE96_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BHE96_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BHE96_00595	COG4956	integral membrane protein (PIN domain superfamily)
BHE96_00615	COG1045	serine acetyltransferase
BHE96_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BHE96_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHE96_00635	COG3688	RNA-binding protein containing a PIN domain
BHE96_00640	COG1595	DNA-templated transcription, initiation
BHE96_00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BHE96_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BHE96_00655	COG0250	Participates in transcription elongation, termination and antitermination
BHE96_00660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BHE96_00675	COG0222	ribosome binding
BHE96_00680	COG2813	Specifically methylates the guanine in position
BHE96_00695	COG1358	cellular component organization or biogenesis
BHE96_00720	COG0596	Alpha beta hydrolase
BHE96_00725	COG0051	transcription antitermination factor activity, RNA binding
BHE96_00740	COG0089	rRNA binding
BHE96_00750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BHE96_00755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BHE96_00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BHE96_00770	COG0255	Belongs to the universal ribosomal protein uL29 family
BHE96_00820	COG1841	ribosomal large subunit assembly
BHE96_00830	COG0201	protein transport
BHE96_00840	COG0024	Methionine aminopeptidase
BHE96_00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BHE96_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BHE96_00880	COG1122	ATPase activity
BHE96_00885	COG1122	ATPase activity
BHE96_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BHE96_00910	COG2226	methyltransferase
BHE96_00915	COG2318	DinB family
BHE96_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
BHE96_00930	COG0489	protein tyrosine kinase activity
BHE96_00940	COG2194	sulfuric ester hydrolase activity
BHE96_00945	COG0726	polysaccharide deacetylase
BHE96_01005	COG0738	Major facilitator superfamily
BHE96_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BHE96_01025	COG0659	secondary active sulfate transmembrane transporter activity
BHE96_01030	COG0385	Bile acid
BHE96_01035	COG2819	hydrolase of the alpha beta superfamily
BHE96_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHE96_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHE96_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHE96_01055	COG2207	Transcriptional regulator
BHE96_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHE96_01060	COG3876	Protein conserved in bacteria
BHE96_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
BHE96_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BHE96_01075	COG1263	PTS System
BHE96_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHE96_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHE96_01090	COG1683	Conserved Protein
BHE96_01120	COG1595	DNA-templated transcription, initiation
BHE96_01125	COG5662	AntiSigma factor
BHE96_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BHE96_01135	COG4856	YbbR-like protein
BHE96_01175	COG1346	cytolysis
BHE96_01180	COG1380	Effector of murein hydrolase LrgA
BHE96_01185	COG1846	Transcriptional regulator
BHE96_01190	COG1113	amino acid transport
BHE96_01195	COG1011	Hydrolase
BHE96_01200	COG4585	Histidine kinase
BHE96_01205	COG2197	response regulator
BHE96_01210	COG1131	(ABC) transporter
BHE96_01250	COG0531	amino acid
BHE96_01255	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BHE96_01270	COG0584	glycerophosphoryl diester phosphodiesterase
BHE96_01275	COG2271	Major facilitator Superfamily
BHE96_01290	COG2368	4-hydroxyphenylacetate
BHE96_01300	COG3409	Peptidoglycan-binding domain 1 protein
BHE96_01315	COG0371	Dehydrogenase
BHE96_01325	COG1183	phosphatidylcholine synthase activity
BHE96_01330	COG0586	Pfam SNARE associated Golgi protein
BHE96_01335	COG0688	phosphatidylethanolamine metabolic process
BHE96_01350	COG1301	dicarboxylic acid transport
BHE96_01355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BHE96_01360	COG0833	amino acid
BHE96_01365	COG2040	homocysteine
BHE96_01370	COG1115	amino acid carrier protein
BHE96_01375	COG2066	Belongs to the glutaminase family
BHE96_01380	COG4191	Histidine kinase
BHE96_01385	COG0784	Response regulator, receiver
BHE96_01405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BHE96_01410	COG0778	Nitroreductase
BHE96_01415	COG0346	lactoylglutathione lyase activity
BHE96_01420	COG2259	Doxx family
BHE96_01425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHE96_01440	COG3773	Cell wall hydrolase
BHE96_01450	COG3540	Alkaline phosphatase
BHE96_01455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BHE96_01460	COG0805	protein transport
BHE96_01470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BHE96_01475	COG0477	Major facilitator Superfamily
BHE96_01480	COG1309	transcriptional regulator
BHE96_01485	COG0252	asparaginase activity
BHE96_01490	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BHE96_01495	COG3012	SEC-C Motif Domain Protein
BHE96_01495	COG1405	negative regulation of cell septum assembly
BHE96_01500	COG0667	Aldo Keto reductase
BHE96_01510	COG1595	DNA-templated transcription, initiation
BHE96_01515	COG1595	DNA-templated transcription, initiation
BHE96_01520	COG1876	peptidase activity
BHE96_01525	COG0457	Tetratricopeptide repeat
BHE96_01530	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_01535	COG0366	Alpha amylase catalytic
BHE96_01545	COG1695	Transcriptional regulator
BHE96_01550	COG0803	Belongs to the bacterial solute-binding protein 9 family
BHE96_01555	COG1121	(ABC) transporter
BHE96_01560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BHE96_01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHE96_01570	COG2310	stress, protein
BHE96_01575	COG2310	stress, protein
BHE96_01580	COG2310	stress, protein
BHE96_01585	COG0861	Integral membrane protein TerC family
BHE96_01595	COG3853	Toxic anion resistance protein (TelA)
BHE96_01600	COG0477	Major facilitator Superfamily
BHE96_01605	COG0517	IMP dehydrogenase activity
BHE96_01605	COG4175	Glycine betaine
BHE96_01610	COG4176	ABC-type proline glycine betaine transport system permease component
BHE96_01615	COG2113	Glycine betaine
BHE96_01620	COG1473	amidohydrolase
BHE96_01625	COG1288	antiporter activity
BHE96_01635	COG0366	Alpha amylase catalytic
BHE96_01645	COG2814	Major facilitator Superfamily
BHE96_01650	COG1846	Transcriptional regulator
BHE96_01655	COG1280	lysine exporter protein (LysE YggA)
BHE96_01660	COG3403	YqcI/YcgG family
BHE96_01665	COG1113	amino acid transport
BHE96_01670	COG3665	Urea carboxylase-associated protein
BHE96_01680	COG2801	Transposase and inactivated derivatives
BHE96_01695	COG1660	Displays ATPase and GTPase activities
BHE96_01700	COG1082	Xylose isomerase domain protein TIM barrel
BHE96_01705	COG2271	Major facilitator Superfamily
BHE96_01710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BHE96_01715	COG3458	cephalosporin-C deacetylase activity
BHE96_01720	COG3541	Predicted nucleotidyltransferase
BHE96_01725	COG0506	proline dehydrogenase activity
BHE96_01730	COG1012	belongs to the aldehyde dehydrogenase family
BHE96_01735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHE96_01740	COG2508	Transcriptional regulator
BHE96_01750	COG1587	Uroporphyrinogen-III synthase
BHE96_01750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BHE96_01755	COG2146	nitrite reductase [NAD(P)H] activity
BHE96_01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BHE96_01765	COG0243	molybdopterin cofactor binding
BHE96_01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BHE96_01775	COG2223	nitrite transmembrane transporter activity
BHE96_01780	COG0523	cobalamin synthesis protein
BHE96_01785	COG1063	alcohol dehydrogenase
BHE96_01790	COG1714	RDD family
BHE96_01800	COG2723	6-phospho-beta-galactosidase activity
BHE96_01810	COG3209	COG3209 Rhs family protein
BHE96_01815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BHE96_01820	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BHE96_01825	COG1733	regulation of RNA biosynthetic process
BHE96_01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_01845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_01850	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BHE96_01865	COG0697	spore germination
BHE96_01870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHE96_01880	COG2364	Membrane
BHE96_01885	COG1126	abc transporter atp-binding protein
BHE96_01890	COG0765	amino acid transport
BHE96_01895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHE96_01900	COG0583	DNA-binding transcription factor activity
BHE96_01905	COG0163	prenyltransferase activity
BHE96_01910	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BHE96_01925	COG3104	oligopeptide transport
BHE96_01930	COG5434	Belongs to the glycosyl hydrolase 28 family
BHE96_01940	COG0697	spore germination
BHE96_01950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BHE96_01965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHE96_01970	COG0765	amino acid transport
BHE96_01975	COG1126	abc transporter atp-binding protein
BHE96_01985	COG2079	MmgE PrpD family protein
BHE96_01990	COG1136	(ABC) transporter
BHE96_01995	COG0577	efflux transmembrane transporter activity
BHE96_02000	COG0745	RESPONSE REGULATOR receiver
BHE96_02005	COG3850	Histidine kinase
BHE96_02005	COG5002	protein histidine kinase activity
BHE96_02010	COG0457	Tetratricopeptide repeat
BHE96_02025	COG0527	aspartate kinase activity
BHE96_02030	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHE96_02035	COG4605	iron ion homeostasis
BHE96_02040	COG4604	ABC transporter, ATP-binding protein
BHE96_02045	COG4607	ABC-type enterochelin transport system periplasmic component
BHE96_02050	COG2814	Major facilitator Superfamily
BHE96_02055	COG1309	transcriptional regulator
BHE96_02060	COG0778	Nitroreductase
BHE96_02065	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BHE96_02070	COG0640	Transcriptional regulator
BHE96_02075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHE96_02080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BHE96_02085	COG1012	belongs to the aldehyde dehydrogenase family
BHE96_02090	COG4975	Glucose uptake
BHE96_02095	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_02100	COG4549	nuclear export factor GLE1
BHE96_02105	COG1276	copper resistance
BHE96_02105	COG2372	response to copper ion
BHE96_02110	COG1349	DNA-binding transcription factor activity
BHE96_02120	COG2213	PTS system mannitol-specific
BHE96_02125	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHE96_02135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BHE96_02140	COG0561	phosphatase activity
BHE96_02150	COG1914	H( )-stimulated, divalent metal cation uptake system
BHE96_02160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BHE96_02165	COG1984	allophanate hydrolase subunit 2
BHE96_02170	COG1414	Transcriptional regulator
BHE96_02175	COG2755	lipolytic protein G-D-S-L family
BHE96_02185	COG2329	Antibiotic biosynthesis monooxygenase
BHE96_02190	COG0768	penicillin binding
BHE96_02195	COG4989	oxidoreductase activity
BHE96_02200	COG3711	transcriptional antiterminator
BHE96_02205	COG0318	PFAM AMP-dependent synthetase and ligase
BHE96_02210	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_02215	COG1917	Cupin 2, conserved barrel domain protein
BHE96_02220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHE96_02225	COG3871	stress protein (general stress protein 26)
BHE96_02240	COG2801	Transposase and inactivated derivatives
BHE96_02245	COG2814	Major facilitator Superfamily
BHE96_02250	COG1522	sequence-specific DNA binding
BHE96_02255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BHE96_02255	COG0551	DNA topoisomerase type I activity
BHE96_02260	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BHE96_02265	COG3706	GGDEF domain
BHE96_02270	COG5298	Protein conserved in bacteria
BHE96_02275	COG1215	transferase activity, transferring glycosyl groups
BHE96_02285	COG0531	amino acid
BHE96_02290	COG0494	nUDIX hydrolase
BHE96_02295	COG0028	Belongs to the TPP enzyme family
BHE96_02325	COG1914	H( )-stimulated, divalent metal cation uptake system
BHE96_02340	COG4876	unkown
BHE96_02350	COG2076	Multidrug Resistance protein
BHE96_02355	COG2217	Heavy metal translocating P-type atpase
BHE96_02360	COG3729	General stress protein
BHE96_02365	COG0662	Cupin 2, conserved barrel domain protein
BHE96_02370	COG2329	Antibiotic biosynthesis monooxygenase
BHE96_02375	COG3546	catalase activity
BHE96_02380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BHE96_02385	COG3290	protein histidine kinase activity
BHE96_02390	COG4565	transcriptional regulatory protein
BHE96_02395	COG1301	dicarboxylic acid transport
BHE96_02400	COG0628	permease
BHE96_02405	COG1131	(ABC) transporter
BHE96_02410	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BHE96_02420	COG1960	acyl-CoA dehydrogenase activity
BHE96_02435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BHE96_02440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHE96_02450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BHE96_02455	COG0513	Belongs to the DEAD box helicase family
BHE96_02460	COG3402	PFAM membrane-flanked domain
BHE96_02465	COG3428	Bacterial PH domain
BHE96_02470	COG0705	Rhomboid family
BHE96_02480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BHE96_02485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHE96_02490	COG0864	Transcriptional regulator
BHE96_02495	COG2337	Toxic component of a toxin-antitoxin (TA) module
BHE96_02500	COG1366	Belongs to the anti-sigma-factor antagonist family
BHE96_02505	COG1366	Belongs to the anti-sigma-factor antagonist family
BHE96_02510	COG2172	sigma factor antagonist activity
BHE96_02515	COG2208	phosphoserine phosphatase activity
BHE96_02520	COG1366	Belongs to the anti-sigma-factor antagonist family
BHE96_02530	COG1191	sigma factor activity
BHE96_02535	COG2208	phosphoserine phosphatase activity
BHE96_02540	COG2183	response to ionizing radiation
BHE96_02605	COG0604	alcohol dehydrogenase
BHE96_02615	COG1959	2 iron, 2 sulfur cluster binding
BHE96_02620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BHE96_02625	COG1090	epimerase
BHE96_02630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BHE96_02645	COG2249	NAD(P)H dehydrogenase (quinone) activity
BHE96_02650	COG0457	Tetratricopeptide repeat
BHE96_02665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BHE96_02670	COG0477	Major facilitator Superfamily
BHE96_02685	COG2030	dehydratase
BHE96_02700	COG1959	2 iron, 2 sulfur cluster binding
BHE96_02705	COG2910	NAD(P)H-binding
BHE96_02710	COG1309	transcriptional regulator
BHE96_02715	COG0300	oxidoreductase activity
BHE96_02735	COG1278	Cold shock
BHE96_02740	COG1329	Transcriptional regulator
BHE96_02745	COG1794	racemase activity, acting on amino acids and derivatives
BHE96_02760	COG1846	Transcriptional regulator
BHE96_02760	COG0456	acetyltransferase
BHE96_02765	COG2271	Major facilitator Superfamily
BHE96_02770	COG3621	Patatin-like phospholipase
BHE96_02780	COG0662	Cupin 2, conserved barrel domain protein
BHE96_02795	COG0277	FAD linked oxidase domain protein
BHE96_02820	COG0662	Cupin 2, conserved barrel domain protein
BHE96_02830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BHE96_02855	COG1064	alcohol dehydrogenase
BHE96_02860	COG0789	Transcriptional regulator
BHE96_02870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHE96_02905	COG2814	Major facilitator Superfamily
BHE96_02910	COG1309	transcriptional regulator
BHE96_02915	COG0697	spore germination
BHE96_02920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHE96_02925	COG5577	PFAM Coat F domain
BHE96_02935	COG1063	alcohol dehydrogenase
BHE96_02940	COG5577	PFAM Coat F domain
BHE96_02950	COG0738	Major facilitator superfamily
BHE96_02960	COG0110	maltose O-acetyltransferase activity
BHE96_02965	COG4585	Histidine kinase
BHE96_02970	COG2197	response regulator
BHE96_02975	COG2409	Drug exporters of the RND superfamily
BHE96_02980	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BHE96_02990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHE96_02995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHE96_03005	COG2814	Major facilitator Superfamily
BHE96_03010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHE96_03020	COG0730	response to heat
BHE96_03025	COG0456	acetyltransferase
BHE96_03030	COG0789	Transcriptional regulator
BHE96_03030	COG4978	Transcriptional regulator
BHE96_03035	COG0697	spore germination
BHE96_03040	COG1051	belongs to the nudix hydrolase family
BHE96_03045	COG0596	Alpha beta hydrolase
BHE96_03050	COG0473	3-isopropylmalate dehydrogenase activity
BHE96_03055	COG1802	Transcriptional regulator
BHE96_03060	COG1819	glycosyl
BHE96_03075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BHE96_03080	COG1388	LysM domain
BHE96_03085	COG2814	Major facilitator Superfamily
BHE96_03090	COG2188	Transcriptional regulator
BHE96_03095	COG2186	Transcriptional regulator
BHE96_03100	COG2807	transmembrane transport
BHE96_03105	COG2076	Multidrug Resistance protein
BHE96_03110	COG2076	Multidrug Resistance protein
BHE96_03115	COG1309	transcriptional regulator
BHE96_03120	COG0531	amino acid
BHE96_03130	COG3832	glyoxalase III activity
BHE96_03135	COG0604	alcohol dehydrogenase
BHE96_03140	COG2814	Major facilitator Superfamily
BHE96_03180	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BHE96_03185	COG0802	atpase or kinase
BHE96_03190	COG1214	PFAM Peptidase M22, glycoprotease
BHE96_03195	COG0456	acetyltransferase
BHE96_03200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BHE96_03205	COG0488	(ABC) transporter
BHE96_03220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BHE96_03225	COG0805	protein transport
BHE96_03235	COG1266	CAAX protease self-immunity
BHE96_03240	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BHE96_03265	COG0457	Tetratricopeptide repeat
BHE96_03270	COG1063	alcohol dehydrogenase
BHE96_03275	COG2211	Major facilitator Superfamily
BHE96_03280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHE96_03290	COG1842	Phage shock protein A
BHE96_03295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BHE96_03300	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BHE96_03305	COG4260	virion core protein, lumpy skin disease virus
BHE96_03310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BHE96_03310	COG2755	lipolytic protein G-D-S-L family
BHE96_03320	COG1595	DNA-templated transcription, initiation
BHE96_03325	COG1063	alcohol dehydrogenase
BHE96_03330	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BHE96_03335	COG0823	Involved in the tonB-independent uptake of proteins
BHE96_03345	COG2132	Multicopper oxidase
BHE96_03350	COG1113	amino acid transport
BHE96_03355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BHE96_03360	COG0714	Associated with various cellular activities
BHE96_03365	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BHE96_03370	COG1305	Transglutaminase-like
BHE96_03390	COG2252	PERMEase
BHE96_03395	COG3064	Membrane
BHE96_03415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BHE96_03420	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BHE96_03425	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BHE96_03430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BHE96_03435	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BHE96_03450	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BHE96_03460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BHE96_03465	COG0138	bifunctional purine biosynthesis protein purh
BHE96_03470	COG0151	Belongs to the GarS family
BHE96_03480	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BHE96_03485	COG1470	cell adhesion involved in biofilm formation
BHE96_03490	COG4496	protein, YerC YecD
BHE96_03495	COG0069	glutamate synthase activity
BHE96_03510	COG0210	DNA helicase
BHE96_03520	COG4851	CamS sex pheromone cAM373 precursor
BHE96_03525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BHE96_03530	COG1285	pathogenesis
BHE96_03535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHE96_03555	COG1309	transcriptional regulator
BHE96_03560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHE96_03565	COG1597	lipid kinase activity
BHE96_03570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHE96_03575	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BHE96_03585	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BHE96_03605	COG5444	nuclease activity
BHE96_03615	COG5444	nuclease activity
BHE96_03640	COG3546	catalase activity
BHE96_03645	COG0454	-acetyltransferase
BHE96_03655	COG2323	membrane
BHE96_03660	COG2329	Antibiotic biosynthesis monooxygenase
BHE96_03665	COG0346	lactoylglutathione lyase activity
BHE96_03670	COG1366	Belongs to the anti-sigma-factor antagonist family
BHE96_03675	COG5583	Uncharacterized small protein (DUF2292)
BHE96_03680	COG0196	riboflavin kinase activity
BHE96_03685	COG0670	Belongs to the BI1 family
BHE96_03690	COG1846	Transcriptional regulator
BHE96_03695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHE96_03705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BHE96_03705	COG2124	cytochrome p450
BHE96_03710	COG1368	sulfuric ester hydrolase activity
BHE96_03715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BHE96_03720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHE96_03725	COG1442	glycosyl transferase family 8
BHE96_03730	COG1216	Glycosyl transferase, family 2
BHE96_03735	COG1442	glycosyl transferase family 8
BHE96_03740	COG2223	nitrite transmembrane transporter activity
BHE96_03745	COG0531	amino acid
BHE96_03750	COG1012	belongs to the aldehyde dehydrogenase family
BHE96_03755	COG0840	transmembrane signaling receptor activity
BHE96_03760	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_03765	COG0457	Tetratricopeptide repeat
BHE96_03765	COG0463	Glycosyl transferase, family 2
BHE96_03770	COG0488	(ABC) transporter
BHE96_03775	COG0789	Transcriptional regulator
BHE96_03780	COG2814	Major facilitator Superfamily
BHE96_03785	COG0488	(ABC) transporter
BHE96_03790	COG0513	Belongs to the DEAD box helicase family
BHE96_03800	COG2130	NADP-dependent
BHE96_03815	COG3866	Pectate lyase
BHE96_03820	COG0471	metal ion transport
BHE96_03850	COG2972	Histidine kinase
BHE96_03850	COG0745	RESPONSE REGULATOR receiver
BHE96_03855	COG3279	Response regulator of the LytR AlgR family
BHE96_03865	COG3764	Sortase (surface protein transpeptidase)
BHE96_03870	COG3290	protein histidine kinase activity
BHE96_03875	COG4565	transcriptional regulatory protein
BHE96_03880	COG3181	Tripartite tricarboxylate transporter family receptor
BHE96_03885	COG2851	Citrate transporter
BHE96_03890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHE96_03895	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BHE96_03905	COG2258	MOSC domain
BHE96_03920	COG0024	Methionine aminopeptidase
BHE96_03925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHE96_03925	COG1263	PTS System
BHE96_03935	COG1368	sulfuric ester hydrolase activity
BHE96_03945	COG0071	Belongs to the small heat shock protein (HSP20) family
BHE96_03960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHE96_03960	COG1263	PTS System
BHE96_03965	COG0366	Alpha amylase catalytic
BHE96_03970	COG2188	Transcriptional regulator
BHE96_03975	COG0778	Nitroreductase
BHE96_03990	COG0737	Belongs to the 5'-nucleotidase family
BHE96_03995	COG0693	protein deglycase activity
BHE96_04000	COG1609	Transcriptional regulator
BHE96_04005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BHE96_04015	COG2814	Major facilitator Superfamily
BHE96_04025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BHE96_04030	COG4980	gas vesicle protein
BHE96_04035	COG1295	ribonuclease BN
BHE96_04040	COG0477	Major facilitator Superfamily
BHE96_04045	COG0387	Pfam Sodium calcium exchanger
BHE96_04055	COG0668	transmembrane transport
BHE96_04060	COG0535	radical SAM domain protein
BHE96_04070	COG0726	polysaccharide deacetylase
BHE96_04075	COG2084	Dehydrogenase
BHE96_04085	COG0598	Magnesium transport protein CorA
BHE96_04090	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BHE96_04095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHE96_04110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHE96_04120	COG4637	Psort location Cytoplasmic, score
BHE96_04125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BHE96_04130	COG0022	dehydrogenase e1 component
BHE96_04135	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHE96_04140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHE96_04145	COG3284	Transcriptional regulator
BHE96_04155	COG1486	melibiose metabolic process
BHE96_04160	COG1737	Transcriptional regulator
BHE96_04165	COG1263	PTS System
BHE96_04165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHE96_04170	COG5434	Belongs to the glycosyl hydrolase 28 family
BHE96_04175	COG1132	(ABC) transporter
BHE96_04180	COG1132	(ABC) transporter
BHE96_04185	COG2259	Doxx family
BHE96_04190	COG2514	catechol 2,3-dioxygenase activity
BHE96_04205	COG1695	Transcriptional regulator
BHE96_04210	COG2249	NAD(P)H dehydrogenase (quinone) activity
BHE96_04215	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BHE96_04220	COG3848	Pyruvate phosphate dikinase
BHE96_04220	COG0574	Belongs to the PEP-utilizing enzyme family
BHE96_04225	COG2732	(Barnase) inhibitor
BHE96_04230	COG2318	DinB family
BHE96_04235	COG2814	Major facilitator Superfamily
BHE96_04240	COG1846	Transcriptional regulator
BHE96_04245	COG0392	lysyltransferase activity
BHE96_04245	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BHE96_04250	COG0384	phenazine biosynthesis protein PhzF
BHE96_04255	COG0778	Nitroreductase
BHE96_04270	COG1090	epimerase
BHE96_04285	COG2814	Major facilitator Superfamily
BHE96_04295	COG3591	Belongs to the peptidase S1B family
BHE96_04310	COG3103	Sh3 type 3 domain protein
BHE96_04315	COG5658	integral membrane protein
BHE96_04320	COG0596	Alpha beta hydrolase
BHE96_04325	COG0463	Glycosyl transferase, family 2
BHE96_04330	COG4485	Bacterial membrane protein, YfhO
BHE96_04335	COG1988	membrane-bound metal-dependent
BHE96_04340	COG1194	a g-specific adenine glycosylase
BHE96_04350	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_04370	COG1132	(ABC) transporter
BHE96_04375	COG4129	membrane
BHE96_04390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BHE96_04395	COG0735	belongs to the Fur family
BHE96_04505	COG1757	Na H antiporter
BHE96_04510	COG3340	Belongs to the peptidase S51 family
BHE96_04520	COG0277	FAD linked oxidase domain protein
BHE96_04530	COG0747	negative chemotaxis
BHE96_04535	COG0601	transmembrane transport
BHE96_04540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHE96_04545	COG0444	Belongs to the ABC transporter superfamily
BHE96_04550	COG4608	Belongs to the ABC transporter superfamily
BHE96_04555	COG0753	catalase activity
BHE96_04565	COG1116	anion transmembrane transporter activity
BHE96_04570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BHE96_04575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BHE96_04595	COG1476	TRANSCRIPTIONal
BHE96_04605	COG3382	B3 4 domain protein
BHE96_04610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BHE96_04620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BHE96_04625	COG0789	Transcriptional regulator
BHE96_04630	COG1664	Polymer-forming cytoskeletal
BHE96_04635	COG1664	Polymer-forming cytoskeletal
BHE96_04640	COG2766	serine protein kinase
BHE96_04655	COG1846	Transcriptional regulator
BHE96_04660	COG1566	PFAM secretion protein HlyD family protein
BHE96_04665	COG2814	Major facilitator Superfamily
BHE96_04670	COG0655	NAD(P)H dehydrogenase (quinone) activity
BHE96_04685	COG1725	Transcriptional regulator
BHE96_04690	COG1131	(ABC) transporter
BHE96_04695	COG1131	(ABC) transporter
BHE96_04700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BHE96_04705	COG1278	Cold shock
BHE96_04715	COG1464	Belongs to the NlpA lipoprotein family
BHE96_04720	COG3706	GGDEF domain
BHE96_04725	COG1823	symporter activity
BHE96_04745	COG5577	PFAM Coat F domain
BHE96_04750	COG4085	toxin activity
BHE96_04750	COG1525	nuclease
BHE96_04750	COG0737	Belongs to the 5'-nucleotidase family
BHE96_04755	COG3764	Sortase (surface protein transpeptidase)
BHE96_04760	COG0564	pseudouridine synthase activity
BHE96_04770	COG0517	IMP dehydrogenase activity
BHE96_04775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHE96_04780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHE96_04780	COG3153	acetyltransferase
BHE96_04785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BHE96_04790	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BHE96_04795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHE96_04805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BHE96_04810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BHE96_04815	COG2203	Gaf domain
BHE96_04815	COG4585	Histidine kinase
BHE96_04820	COG2197	response regulator
BHE96_04825	COG0431	NADPH-dependent FMN reductase
BHE96_04840	COG0791	NLP P60 protein
BHE96_04840	COG1388	LysM domain
BHE96_04845	COG1959	2 iron, 2 sulfur cluster binding
BHE96_04850	COG0668	transmembrane transport
BHE96_04855	COG2719	SpoVR family
BHE96_04860	COG1785	Belongs to the alkaline phosphatase family
BHE96_04865	COG0791	NLP P60 protein
BHE96_04865	COG1388	LysM domain
BHE96_04870	COG0583	DNA-binding transcription factor activity
BHE96_04875	COG0372	Belongs to the citrate synthase family
BHE96_04880	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_04885	COG0531	amino acid
BHE96_04890	COG0733	neurotransmitter:sodium symporter activity
BHE96_04905	COG1595	DNA-templated transcription, initiation
BHE96_04910	COG0204	Acyl-transferase
BHE96_04915	COG1253	flavin adenine dinucleotide binding
BHE96_04920	COG0789	Transcriptional regulator
BHE96_04925	COG0436	Aminotransferase
BHE96_04930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHE96_04935	COG1253	flavin adenine dinucleotide binding
BHE96_04940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BHE96_04945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BHE96_04950	COG0584	glycerophosphoryl diester phosphodiesterase
BHE96_04955	COG0668	transmembrane transport
BHE96_04960	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BHE96_04965	COG0726	polysaccharide deacetylase
BHE96_04970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BHE96_04975	COG3226	Transcriptional regulator
BHE96_04985	COG0589	response to stress
BHE96_04990	COG1132	(ABC) transporter
BHE96_04995	COG1132	(ABC) transporter
BHE96_05000	COG0702	epimerase
BHE96_05020	COG0189	ligase activity
BHE96_05025	COG0189	ligase activity
BHE96_05040	COG4335	DNA alkylation repair
BHE96_05045	COG0561	phosphatase activity
BHE96_05050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHE96_05060	COG0475	glutathione-regulated potassium exporter activity
BHE96_05065	COG0490	domain, Protein
BHE96_05075	COG1024	Enoyl-CoA hydratase
BHE96_05085	COG4152	abc transporter atp-binding protein
BHE96_05090	COG1668	transmembrane transport
BHE96_05095	COG0420	3'-5' exonuclease activity
BHE96_05100	COG4717	serine-type aminopeptidase activity
BHE96_05115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BHE96_05155	COG4980	gas vesicle protein
BHE96_05170	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BHE96_05175	COG0537	adenosine 5'-monophosphoramidase activity
BHE96_05180	COG1131	(ABC) transporter
BHE96_05185	COG4473	ABC transporter
BHE96_05195	COG1473	amidohydrolase
BHE96_05200	COG3069	C4-dicarboxylate transmembrane transporter activity
BHE96_05205	COG2329	Antibiotic biosynthesis monooxygenase
BHE96_05210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHE96_05230	COG1309	transcriptional regulator
BHE96_05235	COG1511	domain protein
BHE96_05240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHE96_05250	COG1363	Peptidase, m42
BHE96_05255	COG1301	dicarboxylic acid transport
BHE96_05265	COG1234	tRNA 3'-trailer cleavage
BHE96_05270	COG0095	Lipoate-protein ligase
BHE96_05275	COG0702	epimerase
BHE96_05280	COG0318	PFAM AMP-dependent synthetase and ligase
BHE96_05290	COG0501	Belongs to the peptidase M48B family
BHE96_05295	COG1404	Belongs to the peptidase S8 family
BHE96_05305	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BHE96_05310	COG0406	alpha-ribazole phosphatase activity
BHE96_05315	COG0183	Belongs to the thiolase family
BHE96_05320	COG0318	PFAM AMP-dependent synthetase and ligase
BHE96_05325	COG1268	BioY protein
BHE96_05330	COG0840	transmembrane signaling receptor activity
BHE96_05335	COG0723	plastoquinol--plastocyanin reductase activity
BHE96_05335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHE96_05340	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_05350	COG4903	ComK protein
BHE96_05370	COG5646	InterPro IPR014922
BHE96_05395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHE96_05410	COG0398	Pfam SNARE associated Golgi protein
BHE96_05415	COG0681	Belongs to the peptidase S26 family
BHE96_05420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHE96_05425	COG1846	Transcriptional regulator
BHE96_05430	COG3180	Ammonia monooxygenase
BHE96_05435	COG2814	Major facilitator Superfamily
BHE96_05445	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BHE96_05450	COG2323	membrane
BHE96_05465	COG0420	3'-5' exonuclease activity
BHE96_05470	COG0419	ATPase involved in DNA repair
BHE96_05475	COG1403	HNH endonuclease
BHE96_05515	COG0179	Fumarylacetoacetate (FAA) hydrolase
BHE96_05535	COG0367	asparagine synthase
BHE96_05540	COG1562	ergosterol biosynthetic process
BHE96_05545	COG0534	Mate efflux family protein
BHE96_05550	COG1917	Cupin 2, conserved barrel domain protein
BHE96_05550	COG2207	Transcriptional regulator
BHE96_05555	COG2318	DinB family
BHE96_05560	COG1279	arginine transmembrane transporter activity
BHE96_05565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHE96_05570	COG1357	PFAM Pentapeptide repeats (8 copies)
BHE96_05575	COG2153	protein acetylation
BHE96_05580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BHE96_05580	COG0646	methionine synthase
BHE96_05590	COG2996	Protein conserved in bacteria
BHE96_05600	COG0840	transmembrane signaling receptor activity
BHE96_05605	COG2124	cytochrome p450
BHE96_05610	COG1307	EDD domain protein, DegV family
BHE96_05615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHE96_05630	COG0561	phosphatase activity
BHE96_05635	COG1073	alpha beta
BHE96_05640	COG2151	metal-sulfur cluster biosynthetic enzyme
BHE96_05650	COG0277	FAD linked oxidase domain protein
BHE96_05655	COG2271	Major facilitator Superfamily
BHE96_05675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BHE96_05680	COG0505	Belongs to the CarA family
BHE96_05685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BHE96_05690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BHE96_05710	COG2267	carboxylic ester hydrolase activity
BHE96_05720	COG1744	ABC transporter substrate-binding protein PnrA-like
BHE96_05735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHE96_05740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHE96_05745	COG5504	Zn-dependent protease
BHE96_05750	COG0444	Belongs to the ABC transporter superfamily
BHE96_05765	COG0601	transmembrane transport
BHE96_05770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHE96_05780	COG0180	Tryptophanyl-tRNA synthetase
BHE96_05790	COG4166	transmembrane transport
BHE96_05795	COG0601	transmembrane transport
BHE96_05800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHE96_05805	COG0444	Belongs to the ABC transporter superfamily
BHE96_05810	COG4608	Belongs to the ABC transporter superfamily
BHE96_05820	COG0456	acetyltransferase
BHE96_05825	COG1393	Belongs to the ArsC family
BHE96_05830	COG0861	Integral membrane protein TerC family
BHE96_05835	COG4862	establishment of competence for transformation
BHE96_05840	COG4469	Competence protein
BHE96_05845	COG1164	Oligoendopeptidase f
BHE96_05855	COG2346	COG2346, Truncated hemoglobins
BHE96_05860	COG0741	lytic transglycosylase activity
BHE96_05865	COG4116	CYTH
BHE96_05875	COG2357	RelA SpoT domain protein
BHE96_05880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BHE96_05885	COG0564	pseudouridine synthase activity
BHE96_05900	COG0569	domain protein
BHE96_05900	COG0475	glutathione-regulated potassium exporter activity
BHE96_05905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BHE96_05910	COG0352	thiamine-phosphate diphosphorylase activity
BHE96_05915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHE96_05920	COG2104	thiamine diphosphate biosynthetic process
BHE96_05930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BHE96_05935	COG0351	phosphomethylpyrimidine kinase
BHE96_05940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BHE96_05995	COG0210	DNA helicase
BHE96_06015	COG1131	(ABC) transporter
BHE96_06025	COG2153	protein acetylation
BHE96_06035	COG2382	esterase
BHE96_06040	COG0626	cystathionine gamma-synthase activity
BHE96_06045	COG0626	cystathionine gamma-synthase activity
BHE96_06065	COG5444	nuclease activity
BHE96_06075	COG0346	lactoylglutathione lyase activity
BHE96_06080	COG2367	Beta-lactamase
BHE96_06085	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BHE96_06095	COG1846	Transcriptional regulator
BHE96_06105	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BHE96_06110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BHE96_06115	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BHE96_06120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHE96_06120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHE96_06125	COG1447	Phosphotransferase system cellobiose-specific component IIA
BHE96_06155	COG1285	pathogenesis
BHE96_06170	COG2205	protein histidine kinase activity
BHE96_06180	COG3383	formate dehydrogenase (NAD+) activity
BHE96_06185	COG2427	Protein of unknown function (DUF1641)
BHE96_06190	COG2124	cytochrome p450
BHE96_06195	COG1819	glycosyl
BHE96_06205	COG1587	Uroporphyrinogen-III synthase
BHE96_06210	COG0390	transport system, permease component
BHE96_06215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BHE96_06220	COG0697	spore germination
BHE96_06225	COG4297	protein containing double-stranded beta helix domain
BHE96_06235	COG1252	NADH dehydrogenase
BHE96_06245	COG2211	Major facilitator Superfamily
BHE96_06250	COG1609	Transcriptional regulator
BHE96_06255	COG0246	Mannitol dehydrogenase
BHE96_06260	COG2721	sulfolactate sulfo-lyase activity
BHE96_06265	COG0745	RESPONSE REGULATOR receiver
BHE96_06270	COG2770	Histidine kinase
BHE96_06270	COG2205	protein histidine kinase activity
BHE96_06290	COG4585	Histidine kinase
BHE96_06295	COG2197	response regulator
BHE96_06320	COG0730	response to heat
BHE96_06325	COG2318	DinB family
BHE96_06330	COG0457	Tetratricopeptide repeat
BHE96_06335	COG3409	Peptidoglycan-binding domain 1 protein
BHE96_06335	COG5632	N-Acetylmuramoyl-L-alanine amidase
BHE96_06335	COG1388	LysM domain
BHE96_06345	COG4195	phage-related replication protein
BHE96_06350	COG2856	Zn peptidase
BHE96_06355	COG1396	sequence-specific DNA binding
BHE96_06365	COG1522	sequence-specific DNA binding
BHE96_06370	COG1484	DNA-dependent DNA replication
BHE96_06385	COG1595	DNA-templated transcription, initiation
BHE96_06390	COG5484	DNA packaging
BHE96_06390	COG3728	DNA packaging
BHE96_06395	COG1783	phage Terminase large subunit
BHE96_06400	COG5518	Phage portal protein
BHE96_06405	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BHE96_06410	COG4653	Phage capsid family
BHE96_06455	COG5412	phage tail tape measure protein
BHE96_06455	COG3953	SLT domain
BHE96_06455	COG3953	SLT domain
BHE96_06455	COG3953	SLT domain
BHE96_06455	COG5412	phage tail tape measure protein
BHE96_06455	COG5412	phage tail tape measure protein
BHE96_06460	COG1652	LysM domain
BHE96_06465	COG4193	domain, Protein
BHE96_06475	COG3628	GPW Gp25 family protein
BHE96_06480	COG3299	homolog of phage Mu protein gp47
BHE96_06485	COG3778	Protein conserved in bacteria
BHE96_06525	COG5632	N-Acetylmuramoyl-L-alanine amidase
BHE96_06525	COG3409	Peptidoglycan-binding domain 1 protein
BHE96_06540	COG0306	phosphate transporter
BHE96_06545	COG1392	Phosphate transport regulator
BHE96_06550	COG0531	amino acid
BHE96_06555	COG0346	lactoylglutathione lyase activity
BHE96_06560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BHE96_06565	COG0463	Glycosyl transferase, family 2
BHE96_06570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHE96_06575	COG0477	Major facilitator Superfamily
BHE96_06580	COG2362	D-Aminopeptidase
BHE96_06585	COG0601	transmembrane transport
BHE96_06590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHE96_06595	COG0444	Belongs to the ABC transporter superfamily
BHE96_06600	COG4166	transmembrane transport
BHE96_06605	COG1619	proteins homologs of microcin C7 resistance protein MccF
BHE96_06610	COG4948	Mandelate Racemase Muconate Lactonizing
BHE96_06615	COG0791	NLP P60 protein
BHE96_06620	COG4608	Belongs to the ABC transporter superfamily
BHE96_06625	COG2706	6-phosphogluconolactonase activity
BHE96_06630	COG1834	amidinotransferase
BHE96_06635	COG1607	acyl-coa hydrolase
BHE96_06640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHE96_06645	COG2076	Multidrug Resistance protein
BHE96_06650	COG2076	Multidrug Resistance protein
BHE96_06655	COG0788	formyltetrahydrofolate deformylase activity
BHE96_06660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BHE96_06670	COG1764	response to oxidative stress
BHE96_06675	COG1846	Transcriptional regulator
BHE96_06680	COG1764	response to oxidative stress
BHE96_06695	COG0457	Tetratricopeptide repeat
BHE96_06695	COG0463	Glycosyl transferase, family 2
BHE96_06705	COG2814	Major facilitator Superfamily
BHE96_06710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHE96_06720	COG1404	Belongs to the peptidase S8 family
BHE96_06725	COG1366	Belongs to the anti-sigma-factor antagonist family
BHE96_06730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BHE96_06735	COG1122	ATPase activity
BHE96_06740	COG4721	ABC-type cobalt transport system, permease component
BHE96_06745	COG1388	LysM domain
BHE96_06745	COG3858	chitin binding
BHE96_06760	COG2239	Acts as a magnesium transporter
BHE96_06765	COG0789	Transcriptional regulator
BHE96_06775	COG1846	Transcriptional regulator
BHE96_06780	COG0726	polysaccharide deacetylase
BHE96_06785	COG3285	dna ligase
BHE96_06785	COG1793	dna ligase
BHE96_06790	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BHE96_06795	COG0586	Pfam SNARE associated Golgi protein
BHE96_06800	COG0861	Integral membrane protein TerC family
BHE96_06805	COG1191	sigma factor activity
BHE96_06830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BHE96_06835	COG2323	membrane
BHE96_06840	COG3594	Acyltransferase
BHE96_06845	COG5002	protein histidine kinase activity
BHE96_06850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BHE96_06865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHE96_06870	COG0436	Aminotransferase
BHE96_06900	COG3852	Histidine kinase
BHE96_06905	COG1846	Transcriptional regulator
BHE96_06910	COG1360	Flagellar Motor Protein
BHE96_06915	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BHE96_06920	COG0542	response to heat
BHE96_06930	COG3949	Membrane
BHE96_06945	COG0720	synthase
BHE96_06950	COG0602	queuosine metabolic process
BHE96_06960	COG1733	regulation of RNA biosynthetic process
BHE96_06965	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_06980	COG4873	Protein conserved in bacteria
BHE96_06990	COG3773	Cell wall hydrolase
BHE96_06995	COG2244	polysaccharide biosynthetic process
BHE96_07000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHE96_07005	COG2217	Heavy metal translocating P-type atpase
BHE96_07010	COG0006	proline dipeptidase activity
BHE96_07015	COG1609	Transcriptional regulator
BHE96_07020	COG3711	transcriptional antiterminator
BHE96_07025	COG2190	(PTS) system
BHE96_07025	COG1263	PTS System
BHE96_07025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHE96_07030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHE96_07035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BHE96_07045	COG1533	DNA photolyase activity
BHE96_07050	COG0840	transmembrane signaling receptor activity
BHE96_07055	COG2084	Dehydrogenase
BHE96_07060	COG2340	Cysteine-rich secretory protein family
BHE96_07065	COG0768	penicillin binding
BHE96_07070	COG4191	Histidine kinase
BHE96_07075	COG0436	Aminotransferase
BHE96_07085	COG0835	chemotaxis
BHE96_07085	COG0784	Response regulator, receiver
BHE96_07095	COG2814	Major facilitator Superfamily
BHE96_07100	COG1376	ErfK ybiS ycfS ynhG family protein
BHE96_07105	COG1408	metallophosphoesterase
BHE96_07110	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_07120	COG2200	EAL domain
BHE96_07125	COG4703	Protein of unknown function (DUF1797)
BHE96_07130	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BHE96_07140	COG0517	IMP dehydrogenase activity
BHE96_07145	COG0583	DNA-binding transcription factor activity
BHE96_07150	COG0716	FMN binding
BHE96_07160	COG0716	FMN binding
BHE96_07180	COG0668	transmembrane transport
BHE96_07185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHE96_07205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BHE96_07210	COG0303	'Molybdopterin
BHE96_07215	COG1763	Mo-molybdopterin cofactor biosynthetic process
BHE96_07220	COG0314	molybdopterin synthase activity
BHE96_07225	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BHE96_07235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHE96_07240	COG1136	(ABC) transporter
BHE96_07245	COG0577	efflux transmembrane transporter activity
BHE96_07250	COG1349	DNA-binding transcription factor activity
BHE96_07255	COG1105	Belongs to the carbohydrate kinase PfkB family
BHE96_07260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHE96_07260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHE96_07260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHE96_07265	COG0681	Belongs to the peptidase S26 family
BHE96_07275	COG0488	(ABC) transporter
BHE96_07280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BHE96_07285	COG2309	aminopeptidase activity
BHE96_07290	COG1077	Cell shape determining protein MreB Mrl
BHE96_07300	COG2002	toxin-antitoxin pair type II binding
BHE96_07305	COG3852	Histidine kinase
BHE96_07310	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BHE96_07310	COG2105	PFAM AIG2 family protein
BHE96_07315	COG0569	domain protein
BHE96_07325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BHE96_07340	COG0561	phosphatase activity
BHE96_07345	COG0242	peptide deformylase activity
BHE96_07355	COG0497	DNA recombination
BHE96_07370	COG3321	synthase
BHE96_07370	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_07370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_07370	COG4221	oxidoreductase activity
BHE96_07375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_07375	COG0300	oxidoreductase activity
BHE96_07375	COG4221	oxidoreductase activity
BHE96_07375	COG3321	synthase
BHE96_07380	COG3321	synthase
BHE96_07380	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_07380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_07380	COG4221	oxidoreductase activity
BHE96_07385	COG0300	oxidoreductase activity
BHE96_07385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_07385	COG3321	synthase
BHE96_07385	COG4221	oxidoreductase activity
BHE96_07390	COG3321	synthase
BHE96_07390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_07390	COG4221	oxidoreductase activity
BHE96_07390	COG0300	oxidoreductase activity
BHE96_07395	COG0300	oxidoreductase activity
BHE96_07395	COG3321	synthase
BHE96_07395	COG4221	oxidoreductase activity
BHE96_07395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_07400	COG4221	oxidoreductase activity
BHE96_07400	COG3321	synthase
BHE96_07400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_07400	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_07405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BHE96_07410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BHE96_07415	COG0022	dehydrogenase e1 component
BHE96_07420	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHE96_07425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHE96_07430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHE96_07445	COG1982	Orn Lys Arg decarboxylase major
BHE96_07470	COG0483	inositol monophosphate 1-phosphatase activity
BHE96_07480	COG3227	Zinc metalloprotease (Elastase)
BHE96_07485	COG1595	DNA-templated transcription, initiation
BHE96_07515	COG4896	Protein conserved in bacteria
BHE96_07525	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BHE96_07530	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BHE96_07535	COG2066	Belongs to the glutaminase family
BHE96_07625	COG0457	Tetratricopeptide repeat
BHE96_07635	COG2433	Pfam Transposase IS66
BHE96_07785	COG0772	Belongs to the SEDS family
BHE96_07790	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BHE96_07805	COG2010	Cytochrome c
BHE96_07805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BHE96_07810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BHE96_07815	COG1845	cytochrome c oxidase, subunit III
BHE96_07820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BHE96_07825	COG3336	cytochrome c oxidase
BHE96_07835	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BHE96_07840	COG2340	Cysteine-rich secretory protein family
BHE96_07855	COG3679	Belongs to the UPF0342 family
BHE96_07865	COG0742	ribosomal rna small subunit methyltransferase
BHE96_07875	COG3314	Sporulation integral membrane protein YlbJ
BHE96_07880	COG1752	Esterase of the alpha-beta hydrolase superfamily
BHE96_07885	COG3480	Lon protease (S16) C-terminal proteolytic domain
BHE96_07890	COG2801	Transposase and inactivated derivatives
BHE96_07905	COG1399	metal-binding, possibly nucleic acid-binding protein
BHE96_07910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BHE96_07925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BHE96_07945	COG4839	cell division protein FtsL
BHE96_07955	COG0768	penicillin binding
BHE96_07975	COG0772	Belongs to the SEDS family
BHE96_07990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BHE96_07995	COG0849	cell division
BHE96_08000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BHE96_08005	COG1404	Belongs to the peptidase S8 family
BHE96_08005	COG4412	M6 family metalloprotease domain protein
BHE96_08015	COG1191	sigma factor activity
BHE96_08020	COG1191	sigma factor activity
BHE96_08025	COG1119	ATPase activity
BHE96_08030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BHE96_08035	COG1873	PFAM PRC-barrel domain
BHE96_08045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BHE96_08055	COG0762	integral membrane protein
BHE96_08060	COG2302	S4 RNA-binding domain
BHE96_08065	COG3599	regulation of cell shape
BHE96_08075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BHE96_08080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BHE96_08090	COG0564	pseudouridine synthase activity
BHE96_08100	COG2233	PERMEase
BHE96_08110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BHE96_08115	COG0505	Belongs to the CarA family
BHE96_08120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BHE96_08135	COG0284	orotidine-5'-phosphate decarboxylase activity
BHE96_08140	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BHE96_08150	COG0306	phosphate transporter
BHE96_08165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BHE96_08170	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BHE96_08175	COG1648	precorrin-2 dehydrogenase activity
BHE96_08190	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BHE96_08195	COG1561	YicC-like family, N-terminal region
BHE96_08200	COG2052	Domain of unknown function (DUF370)
BHE96_08205	COG0194	GDP metabolic process
BHE96_08215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BHE96_08220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BHE96_08225	COG0242	peptide deformylase activity
BHE96_08235	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHE96_08235	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHE96_08245	COG0631	protein serine/threonine phosphatase activity
BHE96_08250	COG2815	serine threonine protein kinase
BHE96_08250	COG0515	serine threonine protein kinase
BHE96_08260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BHE96_08265	COG1564	THIamine pyrophosphokinase
BHE96_08280	COG1302	Protein conserved in bacteria
BHE96_08285	COG1461	Dihydroxyacetone kinase
BHE96_08290	COG1760	l-serine dehydratase
BHE96_08295	COG1760	l-serine dehydratase
BHE96_08300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BHE96_08315	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BHE96_08320	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_08325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_08335	COG1196	nuclear chromosome segregation
BHE96_08340	COG0552	protein localization to endoplasmic reticulum
BHE96_08355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BHE96_08365	COG1837	Belongs to the UPF0109 family
BHE96_08390	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BHE96_08405	COG2257	FlhB HrpN YscU SpaS Family
BHE96_08415	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BHE96_08420	COG0758	DNA mediated transformation
BHE96_08425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BHE96_08435	COG4974	Belongs to the 'phage' integrase family
BHE96_08455	COG1815	bacterial-type flagellum-dependent cell motility
BHE96_08460	COG1558	bacterial-type flagellum-dependent cell motility
BHE96_08465	COG1677	Flagellar hook-basal body complex protein FliE
BHE96_08470	COG1766	The M ring may be actively involved in energy transduction
BHE96_08475	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BHE96_08480	COG1317	bacterial-type flagellum organization
BHE96_08485	COG1157	protein secretion by the type III secretion system
BHE96_08490	COG2882	bacterial-type flagellum organization
BHE96_08495	COG3334	PFAM MgtE intracellular
BHE96_08500	COG3144	bacterial-type flagellum assembly
BHE96_08505	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BHE96_08510	COG4786	Flagellar basal body rod
BHE96_08515	COG1582	Flagellar protein (FlbD)
BHE96_08520	COG1580	Controls the rotational direction of flagella during chemotaxis
BHE96_08525	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BHE96_08530	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BHE96_08530	COG1776	CheC inhibitor of MCP methylation
BHE96_08535	COG2201	protein-glutamate methylesterase activity
BHE96_08540	COG3190	flagellar
BHE96_08545	COG1338	Plays a role in the flagellum-specific transport system
BHE96_08550	COG1987	bacterial-type flagellum assembly
BHE96_08555	COG1684	flagellar biosynthetic protein fliR
BHE96_08560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BHE96_08565	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BHE96_08570	COG1419	protein localization to endoplasmic reticulum
BHE96_08575	COG0455	bacterial-type flagellum organization
BHE96_08580	COG2201	protein-glutamate methylesterase activity
BHE96_08585	COG0643	Histidine kinase
BHE96_08585	COG2198	Histidine kinase
BHE96_08590	COG0835	chemotaxis
BHE96_08595	COG1776	CheC inhibitor of MCP methylation
BHE96_08605	COG1191	sigma factor activity
BHE96_08635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BHE96_08640	COG4589	Belongs to the CDS family
BHE96_08650	COG0750	zinc metalloprotease
BHE96_08660	COG2176	DNA-directed DNA polymerase activity
BHE96_08670	COG0195	Participates in both transcription termination and antitermination
BHE96_08675	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BHE96_08680	COG1358	cellular component organization or biogenesis
BHE96_08690	COG1550	Protein conserved in bacteria
BHE96_08705	COG0196	riboflavin kinase activity
BHE96_08720	COG0726	polysaccharide deacetylase
BHE96_08725	COG0612	Peptidase, M16
BHE96_08730	COG1873	PFAM PRC-barrel domain
BHE96_08735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHE96_08740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BHE96_08745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BHE96_08750	COG0527	aspartate kinase activity
BHE96_08760	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BHE96_08765	COG0740	serine-type endopeptidase activity
BHE96_08775	COG4980	gas vesicle protein
BHE96_08775	COG1674	ftsk spoiiie
BHE96_08780	COG2188	Transcriptional regulator
BHE96_08785	COG2814	Major facilitator Superfamily
BHE96_08790	COG1846	Transcriptional regulator
BHE96_08795	COG1033	growth of symbiont in host cell
BHE96_08795	COG2409	Drug exporters of the RND superfamily
BHE96_08800	COG0612	Peptidase, M16
BHE96_08805	COG0612	Peptidase, M16
BHE96_08810	COG0300	oxidoreductase activity
BHE96_08825	COG1426	Protein conserved in bacteria
BHE96_08830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BHE96_08845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BHE96_08855	COG1692	metallophosphoesterase
BHE96_08860	COG2359	stage V sporulation protein S
BHE96_08880	COG4550	Control of competence regulator ComK, YlbF/YmcA
BHE96_08930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_08935	COG3425	synthase
BHE96_08940	COG1024	Enoyl-CoA hydratase
BHE96_08945	COG1024	Enoyl-CoA hydratase
BHE96_08950	COG0300	oxidoreductase activity
BHE96_08950	COG3321	synthase
BHE96_08950	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_08950	COG0318	PFAM AMP-dependent synthetase and ligase
BHE96_08950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_08955	COG3321	synthase
BHE96_08955	COG4221	oxidoreductase activity
BHE96_08955	COG0300	oxidoreductase activity
BHE96_08955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_08960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHE96_08960	COG3321	synthase
BHE96_08960	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_08960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_08960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_08960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHE96_08960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_08960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_08960	COG3321	synthase
BHE96_08960	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_08965	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_08965	COG3321	synthase
BHE96_08965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_08965	COG4221	oxidoreductase activity
BHE96_08970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_08970	COG3321	synthase
BHE96_08970	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BHE96_08970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BHE96_08975	COG2124	cytochrome p450
BHE96_08980	COG3209	COG3209 Rhs family protein
BHE96_08985	COG3619	membrane
BHE96_08995	COG2801	Transposase and inactivated derivatives
BHE96_09005	COG1404	Belongs to the peptidase S8 family
BHE96_09015	COG4195	phage-related replication protein
BHE96_09020	COG1764	response to oxidative stress
BHE96_09030	COG2076	Multidrug Resistance protein
BHE96_09070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHE96_09075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHE96_09080	COG4112	unkown
BHE96_09085	COG0860	N-Acetylmuramoyl-L-alanine amidase
BHE96_09095	COG0464	growth
BHE96_09100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BHE96_09105	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BHE96_09110	COG0789	Transcriptional regulator
BHE96_09115	COG0174	glutamine synthetase
BHE96_09125	COG2211	Major facilitator Superfamily
BHE96_09130	COG3507	Belongs to the glycosyl hydrolase 43 family
BHE96_09145	COG1070	Carbohydrate kinase
BHE96_09150	COG0574	Belongs to the PEP-utilizing enzyme family
BHE96_09150	COG3848	Pyruvate phosphate dikinase
BHE96_09185	COG1064	alcohol dehydrogenase
BHE96_09195	COG0456	acetyltransferase
BHE96_09235	COG3397	chitin binding
BHE96_09250	COG5434	Belongs to the glycosyl hydrolase 28 family
BHE96_09255	COG0756	dUTP diphosphatase activity
BHE96_09260	COG4195	phage-related replication protein
BHE96_09290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BHE96_09300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BHE96_09320	COG0785	Cytochrome C biogenesis protein
BHE96_09325	COG2201	protein-glutamate methylesterase activity
BHE96_09330	COG4846	Membrane protein involved in cytochrome C biogenesis
BHE96_09340	COG0071	Belongs to the small heat shock protein (HSP20) family
BHE96_09355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BHE96_09360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHE96_09380	COG0824	Thioesterase
BHE96_09390	COG4841	protein insertion into membrane
BHE96_09400	COG1832	CoA-binding protein
BHE96_09405	COG0187	DNA topoisomerase II activity
BHE96_09410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BHE96_09420	COG1115	amino acid carrier protein
BHE96_09430	COG1063	alcohol dehydrogenase
BHE96_09435	COG0800	Aldolase
BHE96_09440	COG1312	Catalyzes the dehydration of D-mannonate
BHE96_09445	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_09450	COG1609	Transcriptional regulator
BHE96_09455	COG2271	Major facilitator Superfamily
BHE96_09480	COG0577	efflux transmembrane transporter activity
BHE96_09480	COG1136	(ABC) transporter
BHE96_09510	COG2205	protein histidine kinase activity
BHE96_09515	COG0745	RESPONSE REGULATOR receiver
BHE96_09525	COG3507	Belongs to the glycosyl hydrolase 43 family
BHE96_09550	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_09555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BHE96_09560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BHE96_09565	COG2610	gluconate transmembrane transporter activity
BHE96_09570	COG2124	cytochrome p450
BHE96_09575	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BHE96_09590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BHE96_09600	COG2246	polysaccharide biosynthetic process
BHE96_09610	COG0586	Pfam SNARE associated Golgi protein
BHE96_09615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BHE96_09620	COG1024	Enoyl-CoA hydratase
BHE96_09625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BHE96_09630	COG0511	ligase activity, forming carbon-carbon bonds
BHE96_09635	COG0439	Biotin carboxylase
BHE96_09640	COG0318	PFAM AMP-dependent synthetase and ligase
BHE96_09645	COG1960	acyl-CoA dehydrogenase activity
BHE96_09650	COG1649	PFAM Uncharacterised BCR, COG1649
BHE96_09660	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BHE96_09660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_09665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_09670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_09675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_09680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_09690	COG2027	D-alanyl-D-alanine carboxypeptidase
BHE96_09695	COG2017	converts alpha-aldose to the beta-anomer
BHE96_09700	COG0534	Mate efflux family protein
BHE96_09715	COG0582	viral genome integration into host DNA
BHE96_09720	COG0166	Belongs to the GPI family
BHE96_09725	COG0405	Gamma-glutamyltransferase
BHE96_09730	COG2814	Major facilitator Superfamily
BHE96_09735	COG0640	Transcriptional regulator
BHE96_09740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BHE96_09755	COG0604	alcohol dehydrogenase
BHE96_09760	COG0493	'glutamate synthase
BHE96_09765	COG0069	glutamate synthase activity
BHE96_09765	COG0070	glutamate synthase
BHE96_09765	COG0067	glutamate synthase
BHE96_09770	COG0583	DNA-binding transcription factor activity
BHE96_09775	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BHE96_09795	COG0300	oxidoreductase activity
BHE96_09800	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BHE96_09815	COG1070	Carbohydrate kinase
BHE96_09820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BHE96_09825	COG0243	molybdopterin cofactor binding
BHE96_09860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHE96_09865	COG2207	Transcriptional regulator
BHE96_09865	COG0662	Cupin 2, conserved barrel domain protein
BHE96_09870	COG1309	transcriptional regulator
BHE96_09875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHE96_09885	COG0640	Transcriptional regulator
BHE96_09890	COG0741	lytic transglycosylase activity
BHE96_09895	COG2322	membrane
BHE96_09910	COG1619	proteins homologs of microcin C7 resistance protein MccF
BHE96_09920	COG3584	3D domain protein
BHE96_09920	COG1388	LysM domain
BHE96_09925	COG0514	ATP-dependent DNA helicase (RecQ)
BHE96_09935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BHE96_09940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BHE96_09955	COG0071	Belongs to the small heat shock protein (HSP20) family
BHE96_09985	COG1012	belongs to the aldehyde dehydrogenase family
BHE96_09990	COG1657	PFAM Prenyltransferase squalene oxidase
BHE96_09995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BHE96_10000	COG0733	neurotransmitter:sodium symporter activity
BHE96_10005	COG0385	Bile acid
BHE96_10010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHE96_10015	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHE96_10025	COG4548	von Willebrand factor, type A
BHE96_10030	COG0714	Associated with various cellular activities
BHE96_10035	COG2032	superoxide dismutase activity
BHE96_10040	COG0791	NLP P60 protein
BHE96_10040	COG1388	LysM domain
BHE96_10045	COG1819	glycosyl
BHE96_10050	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BHE96_10055	COG0534	Mate efflux family protein
BHE96_10060	COG1366	Belongs to the anti-sigma-factor antagonist family
BHE96_10065	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BHE96_10070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BHE96_10080	COG2962	Rard protein
BHE96_10095	COG1942	4-Oxalocrotonate Tautomerase
BHE96_10105	COG1733	regulation of RNA biosynthetic process
BHE96_10110	COG0778	Nitroreductase
BHE96_10115	COG0400	carboxylic ester hydrolase activity
BHE96_10120	COG0346	lactoylglutathione lyase activity
BHE96_10130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHE96_10140	COG2723	6-phospho-beta-galactosidase activity
BHE96_10145	COG2188	Transcriptional regulator
BHE96_10150	COG0793	Belongs to the peptidase S41A family
BHE96_10150	COG3409	Peptidoglycan-binding domain 1 protein
BHE96_10155	COG2226	methyltransferase
BHE96_10165	COG1876	peptidase activity
BHE96_10180	COG0671	phosphoesterase, PA-phosphatase related
BHE96_10210	COG1509	lysine 2,3-aminomutase activity
BHE96_10215	COG0456	acetyltransferase
BHE96_10220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BHE96_10225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BHE96_10230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BHE96_10235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BHE96_10250	COG0456	acetyltransferase
BHE96_10255	COG0463	Glycosyl transferase, family 2
BHE96_10270	COG4641	Protein conserved in bacteria
BHE96_10280	COG1086	Polysaccharide biosynthesis protein
BHE96_10315	COG0457	Tetratricopeptide repeat
BHE96_10325	COG1012	belongs to the aldehyde dehydrogenase family
BHE96_10345	COG5444	nuclease activity
BHE96_10350	COG4282	regulation of fungal-type cell wall biogenesis
BHE96_10355	COG1525	nuclease
BHE96_10360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BHE96_10380	COG1846	Transcriptional regulator
BHE96_10385	COG4698	Protein conserved in bacteria
BHE96_10390	COG2755	lipolytic protein G-D-S-L family
BHE96_10395	COG1999	signal sequence binding
BHE96_10405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BHE96_10410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BHE96_10415	COG1272	protein, Hemolysin III
BHE96_10420	COG0204	Acyl-transferase
BHE96_10425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BHE96_10440	COG2136	Putative SAM-dependent methyltransferase
BHE96_10440	COG2521	methyltransferase
BHE96_10455	COG1413	lyase activity
BHE96_10460	COG1418	mRNA catabolic process
BHE96_10465	COG0386	Belongs to the glutathione peroxidase family
BHE96_10475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BHE96_10480	COG1278	Cold shock
BHE96_10500	COG0328	RNA-DNA hybrid ribonuclease activity
BHE96_10505	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BHE96_10510	COG0328	RNA-DNA hybrid ribonuclease activity
BHE96_10520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BHE96_10530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BHE96_10535	COG1755	Isoprenylcysteine carboxyl methyltransferase
BHE96_10540	COG3424	synthase
BHE96_10560	COG2323	membrane
BHE96_10565	COG1335	isochorismatase
BHE96_10580	COG3331	DNA recombination
BHE96_10655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BHE96_10660	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BHE96_10685	COG0756	dUTP diphosphatase activity
BHE96_10690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHE96_10730	COG1780	Probably involved in ribonucleotide reductase function
BHE96_10815	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BHE96_10820	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BHE96_10830	COG3584	3D domain protein
BHE96_10835	COG0587	DNA-directed DNA polymerase activity
BHE96_10840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BHE96_10845	COG0358	DNA primase activity
BHE96_10850	COG0305	Participates in initiation and elongation during chromosome replication
BHE96_10860	COG2887	Belongs to the helicase family. UvrD subfamily
BHE96_10890	COG5434	Belongs to the glycosyl hydrolase 28 family
BHE96_10890	COG3420	alginic acid biosynthetic process
BHE96_10895	COG4195	phage-related replication protein
BHE96_10915	COG2135	peptidase activity
BHE96_10920	COG1793	dna ligase
BHE96_10965	COG4474	Belongs to the UPF0398 family
BHE96_11060	COG3655	Transcriptional regulator
BHE96_11150	COG3655	Transcriptional regulator
BHE96_11240	COG0776	regulation of translation
BHE96_11370	COG0582	viral genome integration into host DNA
BHE96_11390	COG1196	nuclear chromosome segregation
BHE96_11390	COG0741	lytic transglycosylase activity
BHE96_11390	COG0739	heme binding
BHE96_11410	COG5434	Belongs to the glycosyl hydrolase 28 family
BHE96_11415	COG5632	N-Acetylmuramoyl-L-alanine amidase
BHE96_11415	COG3409	Peptidoglycan-binding domain 1 protein
BHE96_11440	COG0457	Tetratricopeptide repeat
BHE96_11445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHE96_11475	COG5444	nuclease activity
BHE96_11485	COG4282	regulation of fungal-type cell wall biogenesis
BHE96_11490	COG1525	nuclease
BHE96_11510	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BHE96_11515	COG1199	ATP-dependent helicase activity
BHE96_11530	COG0116	Belongs to the methyltransferase superfamily
BHE96_11555	COG3359	exonuclease
BHE96_11560	COG1205	dead DEAH box helicase
BHE96_11560	COG1111	helicase
BHE96_11565	COG2190	(PTS) system
BHE96_11570	COG0071	Belongs to the small heat shock protein (HSP20) family
BHE96_11610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHE96_11610	COG4499	WXG100 protein secretion system (Wss), protein YukC
BHE96_11620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BHE96_11625	COG3935	DnaD domain protein
BHE96_11635	COG0436	Aminotransferase
BHE96_11640	COG5353	protein conserved in bacteria
BHE96_11650	COG1199	ATP-dependent helicase activity
BHE96_11650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BHE96_11680	COG0438	transferase activity, transferring glycosyl groups
BHE96_11685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BHE96_11700	COG1694	Mazg nucleotide pyrophosphohydrolase
BHE96_11705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHE96_11710	COG2140	Oxalate decarboxylase
BHE96_11720	COG4347	Protein of unknown function (DUF1405)
BHE96_11725	COG2010	Cytochrome c
BHE96_11725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BHE96_11730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BHE96_11735	COG0723	plastoquinol--plastocyanin reductase activity
BHE96_11750	COG0457	Tetratricopeptide repeat
BHE96_11760	COG0287	Prephenate dehydrogenase
BHE96_11795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHE96_11800	COG4401	Chorismate mutase type I
BHE96_11815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BHE96_11820	COG0105	UTP biosynthetic process
BHE96_11825	COG0142	geranyltranstransferase activity
BHE96_11835	COG0142	geranyltranstransferase activity
BHE96_11850	COG0776	regulation of translation
BHE96_11855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BHE96_11895	COG0539	negative regulation of cytoplasmic translation
BHE96_11905	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BHE96_11910	COG2959	enzyme of heme biosynthesis
BHE96_11915	COG3773	Cell wall hydrolase
BHE96_11915	COG3409	Peptidoglycan-binding domain 1 protein
BHE96_11920	COG2339	peptidase activity
BHE96_11925	COG0492	ferredoxin-NADP+ reductase activity
BHE96_11930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BHE96_11935	COG4862	establishment of competence for transformation
BHE96_11940	COG1408	metallophosphoesterase
BHE96_11950	COG1388	LysM domain
BHE96_11955	COG1266	CAAX protease self-immunity
BHE96_11960	COG0514	ATP-dependent DNA helicase (RecQ)
BHE96_11965	COG4955	Helix-turn-helix domain
BHE96_11970	COG1141	Ferredoxin
BHE96_11975	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BHE96_11980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BHE96_11990	COG1595	DNA-templated transcription, initiation
BHE96_11995	COG5002	protein histidine kinase activity
BHE96_12000	COG0745	RESPONSE REGULATOR receiver
BHE96_12005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHE96_12010	COG1333	cytochrome c biogenesis protein
BHE96_12015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHE96_12020	COG1187	pseudouridine synthase activity
BHE96_12025	COG0700	Nucleoside recognition
BHE96_12030	COG2715	membrane protein required for spore maturation
BHE96_12035	COG1686	Belongs to the peptidase S11 family
BHE96_12060	COG1547	Domain of unknown function (DUF309)
BHE96_12070	COG0456	acetyltransferase
BHE96_12085	COG0307	riboflavin synthase, alpha
BHE96_12090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHE96_12090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHE96_12100	COG0681	Belongs to the peptidase S26 family
BHE96_12110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BHE96_12115	COG4086	secreted protein
BHE96_12120	COG0019	diaminopimelate decarboxylase activity
BHE96_12125	COG0697	spore germination
BHE96_12140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHE96_12160	COG1191	sigma factor activity
BHE96_12170	COG1366	Belongs to the anti-sigma-factor antagonist family
BHE96_12175	COG1686	Belongs to the peptidase S11 family
BHE96_12180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BHE96_12185	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BHE96_12190	COG4974	Belongs to the 'phage' integrase family
BHE96_12200	COG0735	belongs to the Fur family
BHE96_12205	COG1300	Membrane
BHE96_12220	COG0281	malic enzyme
BHE96_12225	COG1757	Na H antiporter
BHE96_12230	COG1027	Aspartate ammonia-lyase
BHE96_12235	COG0252	asparaginase activity
BHE96_12240	COG1396	sequence-specific DNA binding
BHE96_12245	COG1379	DNA repair
BHE96_12250	COG0494	nUDIX hydrolase
BHE96_12260	COG0667	Aldo Keto reductase
BHE96_12270	COG1073	alpha beta
BHE96_12280	COG4918	Iron-sulphur cluster biosynthesis
BHE96_12285	COG0456	acetyltransferase
BHE96_12285	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BHE96_12290	COG2329	Antibiotic biosynthesis monooxygenase
BHE96_12295	COG0456	acetyltransferase
BHE96_12300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHE96_12315	COG0628	permease
BHE96_12320	COG0346	lactoylglutathione lyase activity
BHE96_12330	COG3048	D-serine ammonia-lyase activity
BHE96_12335	COG0300	oxidoreductase activity
BHE96_12340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHE96_12345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BHE96_12350	COG1024	Enoyl-CoA hydratase
BHE96_12355	COG3425	synthase
BHE96_12360	COG2124	cytochrome p450
BHE96_12365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_12365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_12365	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_12365	COG3321	synthase
BHE96_12365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHE96_12370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHE96_12370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_12370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_12370	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_12370	COG3321	synthase
BHE96_12375	COG0318	PFAM AMP-dependent synthetase and ligase
BHE96_12375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_12375	COG3321	synthase
BHE96_12375	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_12375	COG0300	oxidoreductase activity
BHE96_12380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_12380	COG3321	synthase
BHE96_12380	COG0300	oxidoreductase activity
BHE96_12380	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_12380	COG0318	PFAM AMP-dependent synthetase and ligase
BHE96_12385	COG3321	synthase
BHE96_12385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_12385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_12385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHE96_12385	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_12390	COG0300	oxidoreductase activity
BHE96_12390	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_12390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_12390	COG0318	PFAM AMP-dependent synthetase and ligase
BHE96_12390	COG3321	synthase
BHE96_12395	COG3321	synthase
BHE96_12395	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_12395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_12395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHE96_12395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHE96_12400	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_12405	COG0318	PFAM AMP-dependent synthetase and ligase
BHE96_12420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BHE96_12420	COG2070	2-Nitropropane dioxygenase
BHE96_12430	COG0250	Participates in transcription elongation, termination and antitermination
BHE96_12455	COG0596	Alpha beta hydrolase
BHE96_12470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BHE96_12475	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BHE96_12490	COG0706	membrane insertase activity
BHE96_12495	COG2195	Cleaves the N-terminal amino acid of tripeptides
BHE96_12500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BHE96_12505	COG0346	lactoylglutathione lyase activity
BHE96_12510	COG1376	ErfK ybiS ycfS ynhG family protein
BHE96_12515	COG4129	membrane
BHE96_12520	COG1126	abc transporter atp-binding protein
BHE96_12525	COG0765	amino acid transport
BHE96_12530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHE96_12540	COG1597	lipid kinase activity
BHE96_12545	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHE96_12550	COG0022	dehydrogenase e1 component
BHE96_12555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BHE96_12560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHE96_12565	COG3426	butyrate kinase activity
BHE96_12570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BHE96_12575	COG0280	phosphate acetyltransferase
BHE96_12580	COG3829	transcription factor binding
BHE96_12580	COG3290	protein histidine kinase activity
BHE96_12590	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BHE96_12595	COG2079	MmgE PrpD family protein
BHE96_12600	COG0372	Belongs to the citrate synthase family
BHE96_12605	COG1960	acyl-CoA dehydrogenase activity
BHE96_12610	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHE96_12615	COG0183	Belongs to the thiolase family
BHE96_12620	COG0584	glycerophosphoryl diester phosphodiesterase
BHE96_12625	COG0860	N-Acetylmuramoyl-L-alanine amidase
BHE96_12650	COG1902	pentaerythritol trinitrate reductase activity
BHE96_12665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHE96_12670	COG0745	RESPONSE REGULATOR receiver
BHE96_12675	COG0750	zinc metalloprotease
BHE96_12680	COG0497	DNA recombination
BHE96_12690	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BHE96_12725	COG1302	Protein conserved in bacteria
BHE96_12735	COG0511	ligase activity, forming carbon-carbon bonds
BHE96_12775	COG3854	ATPases associated with a variety of cellular activities
BHE96_12790	COG0006	proline dipeptidase activity
BHE96_12800	COG3872	metal-dependent enzyme
BHE96_12810	COG1752	Esterase of the alpha-beta hydrolase superfamily
BHE96_12825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHE96_12845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BHE96_12860	COG1396	sequence-specific DNA binding
BHE96_12870	COG0681	Belongs to the peptidase S26 family
BHE96_12895	COG4940	Competence protein ComGF
BHE96_12905	COG4970	Tfp pilus assembly protein FimT
BHE96_12910	COG4537	Required for transformation and DNA binding
BHE96_12915	COG1459	type II secretion system
BHE96_12920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHE96_12925	COG0598	Magnesium transport protein CorA
BHE96_12930	COG1253	flavin adenine dinucleotide binding
BHE96_12935	COG1366	Belongs to the anti-sigma-factor antagonist family
BHE96_12945	COG1393	Belongs to the ArsC family
BHE96_12955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHE96_12965	COG0011	TIGRFAM Protein of
BHE96_12975	COG2866	Carboxypeptidase
BHE96_12980	COG1940	carbohydrate kinase activity
BHE96_12985	COG4483	Protein conserved in bacteria
BHE96_12990	COG1757	Na H antiporter
BHE96_12995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BHE96_13000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BHE96_13010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BHE96_13015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BHE96_13020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BHE96_13025	COG0581	inorganic phosphate transmembrane transporter activity
BHE96_13030	COG0573	inorganic phosphate transmembrane transporter activity
BHE96_13035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BHE96_13045	COG0477	Major facilitator Superfamily
BHE96_13050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BHE96_13055	COG2839	Protein conserved in bacteria
BHE96_13060	COG5521	maltodextrose utilization protein MalA
BHE96_13065	COG1388	LysM domain
BHE96_13075	COG4709	membrane
BHE96_13080	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BHE96_13085	COG0735	belongs to the Fur family
BHE96_13090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHE96_13105	COG0513	Belongs to the DEAD box helicase family
BHE96_13120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BHE96_13125	COG2384	SAM-dependent methyltransferase
BHE96_13130	COG2010	Cytochrome c
BHE96_13135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHE96_13140	COG0358	DNA primase activity
BHE96_13155	COG0517	IMP dehydrogenase activity
BHE96_13160	COG0751	glycine-tRNA ligase activity
BHE96_13180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BHE96_13185	COG0295	cytidine deaminase activity
BHE96_13190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BHE96_13200	COG1480	7TM receptor with intracellular HD hydrolase
BHE96_13205	COG1702	phosphate starvation-inducible protein PhoH
BHE96_13210	COG0561	phosphatase activity
BHE96_13225	COG4864	UPF0365 protein
BHE96_13230	COG1030	water channel activity
BHE96_13235	COG1610	YqeY-like protein
BHE96_13240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BHE96_13245	COG1283	sodium-dependent phosphate transmembrane transporter activity
BHE96_13250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BHE96_13255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BHE96_13285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHE96_13300	COG0860	N-Acetylmuramoyl-L-alanine amidase
BHE96_13315	COG1466	dna polymerase III delta subunit
BHE96_13325	COG2333	competence protein COMEC
BHE96_13325	COG0658	competence protein
BHE96_13330	COG2131	deaminase
BHE96_13335	COG1555	photosystem II stabilization
BHE96_13335	COG1596	polysaccharide export
BHE96_13340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BHE96_13345	COG2226	methyltransferase
BHE96_13350	COG0799	negative regulation of ribosome biogenesis
BHE96_13355	COG1713	HD superfamily hydrolase involved in NAD metabolism
BHE96_13365	COG1534	Rna-binding protein
BHE96_13370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BHE96_13375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BHE96_13380	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BHE96_13390	COG2755	lipolytic protein G-D-S-L family
BHE96_13395	COG0726	polysaccharide deacetylase
BHE96_13400	COG0398	Pfam SNARE associated Golgi protein
BHE96_13440	COG2207	Transcriptional regulator
BHE96_13440	COG3708	Transcriptional regulator
BHE96_13450	COG0563	adenylate kinase activity
BHE96_13465	COG0456	acetyltransferase
BHE96_13470	COG2318	DinB family
BHE96_13480	COG0561	phosphatase activity
BHE96_13485	COG0561	phosphatase activity
BHE96_13495	COG1482	cell wall glycoprotein biosynthetic process
BHE96_13500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHE96_13500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHE96_13500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHE96_13505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHE96_13505	COG3711	transcriptional antiterminator
BHE96_13515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BHE96_13520	COG0583	DNA-binding transcription factor activity
BHE96_13525	COG2814	Major facilitator Superfamily
BHE96_13530	COG2124	cytochrome p450
BHE96_13530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BHE96_13535	COG1309	transcriptional regulator
BHE96_13540	COG2226	methyltransferase
BHE96_13555	COG2116	formate transmembrane transporter activity
BHE96_13560	COG5609	conserved protein (DUF2294)
BHE96_13565	COG3383	formate dehydrogenase (NAD+) activity
BHE96_13570	COG2427	Protein of unknown function (DUF1641)
BHE96_13580	COG0626	cystathionine gamma-synthase activity
BHE96_13585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BHE96_13610	COG0768	penicillin binding
BHE96_13640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BHE96_13665	COG0628	permease
BHE96_13670	COG1126	abc transporter atp-binding protein
BHE96_13675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHE96_13680	COG0765	amino acid transport
BHE96_13685	COG0765	amino acid transport
BHE96_13700	COG3881	PFAM PRC-barrel domain
BHE96_13705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BHE96_13710	COG0457	Tetratricopeptide repeat
BHE96_13720	COG1104	cysteine desulfurase activity
BHE96_13725	COG1959	2 iron, 2 sulfur cluster binding
BHE96_13730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BHE96_13740	COG2801	Transposase and inactivated derivatives
BHE96_13745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BHE96_13765	COG0860	N-Acetylmuramoyl-L-alanine amidase
BHE96_13765	COG3103	Sh3 type 3 domain protein
BHE96_13765	COG4991	sh3 domain protein
BHE96_13775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BHE96_13785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BHE96_13785	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BHE96_13790	COG5416	Lipopolysaccharide assembly protein A domain
BHE96_13795	COG0490	domain, Protein
BHE96_13800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHE96_13800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHE96_13810	COG2244	polysaccharide biosynthetic process
BHE96_13815	COG2323	membrane
BHE96_13825	COG1862	Preprotein translocase
BHE96_13870	COG1388	LysM domain
BHE96_13880	COG0157	Belongs to the NadC ModD family
BHE96_13885	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BHE96_13890	COG1104	cysteine desulfurase activity
BHE96_13895	COG1827	regulation of RNA biosynthetic process
BHE96_13900	COG0077	Prephenate dehydratase
BHE96_13915	COG3290	protein histidine kinase activity
BHE96_13920	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BHE96_13925	COG2868	ribosomal protein
BHE96_13935	COG1994	Peptidase M50
BHE96_13940	COG0739	heme binding
BHE96_13945	COG2894	cell division
BHE96_13955	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BHE96_13960	COG1792	Involved in formation and maintenance of cell shape
BHE96_13965	COG1077	Cell shape determining protein MreB Mrl
BHE96_13985	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BHE96_13990	COG0285	dihydrofolate synthase activity
BHE96_13995	COG0525	valine-tRNA ligase activity
BHE96_14005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BHE96_14010	COG1388	LysM domain
BHE96_14020	COG0113	porphobilinogen synthase activity
BHE96_14025	COG1587	Uroporphyrinogen-III synthase
BHE96_14035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHE96_14055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BHE96_14060	COG0470	DNA polymerase III
BHE96_14060	COG1067	ATP-dependent peptidase activity
BHE96_14075	COG1477	protein flavinylation
BHE96_14075	COG0457	Tetratricopeptide repeat
BHE96_14090	COG0473	3-isopropylmalate dehydrogenase activity
BHE96_14105	COG0440	acetolactate synthase activity
BHE96_14110	COG0028	Belongs to the TPP enzyme family
BHE96_14155	COG0622	Phosphoesterase
BHE96_14160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BHE96_14170	COG5401	PFAM Sporulation and spore germination
BHE96_14180	COG1846	Transcriptional regulator
BHE96_14185	COG2197	response regulator
BHE96_14190	COG0824	Thioesterase
BHE96_14195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BHE96_14200	COG1053	succinate dehydrogenase
BHE96_14205	COG2009	succinate dehydrogenase
BHE96_14210	COG1719	4-vinyl reductase, 4VR
BHE96_14215	COG0527	aspartate kinase activity
BHE96_14230	COG3118	belongs to the thioredoxin family
BHE96_14235	COG3534	alpha-L-arabinofuranosidase
BHE96_14240	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BHE96_14245	COG2086	electron transfer activity
BHE96_14250	COG1024	Enoyl-CoA hydratase
BHE96_14255	COG1309	transcriptional regulator
BHE96_14260	COG0318	PFAM AMP-dependent synthetase and ligase
BHE96_14270	COG3766	membrane
BHE96_14280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BHE96_14280	COG1796	DNA polymerase
BHE96_14285	COG1286	toxin biosynthetic process
BHE96_14300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHE96_14300	COG0072	phenylalanine-tRNA ligase activity
BHE96_14305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BHE96_14310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHE96_14320	COG3835	regulator
BHE96_14325	COG0277	FAD linked oxidase domain protein
BHE96_14330	COG0247	lactate metabolic process
BHE96_14335	COG1966	Carbon starvation protein
BHE96_14340	COG3534	alpha-L-arabinofuranosidase
BHE96_14345	COG0395	ABC-type sugar transport system, permease component
BHE96_14350	COG1175	transmembrane transport
BHE96_14355	COG1653	transport
BHE96_14365	COG0647	UMP catabolic process
BHE96_14370	COG0235	Class ii aldolase
BHE96_14375	COG1069	ribulokinase activity
BHE96_14380	COG2160	L-arabinose isomerase activity
BHE96_14385	COG3507	Belongs to the glycosyl hydrolase 43 family
BHE96_14390	COG1363	Peptidase, m42
BHE96_14400	COG3326	Membrane
BHE96_14415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BHE96_14420	COG1346	cytolysis
BHE96_14425	COG1380	Effector of murein hydrolase LrgA
BHE96_14430	COG3279	Response regulator of the LytR AlgR family
BHE96_14435	COG3275	phosphorelay sensor kinase activity
BHE96_14460	COG0398	Pfam SNARE associated Golgi protein
BHE96_14465	COG1484	DNA-dependent DNA replication
BHE96_14485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BHE96_14490	COG1733	regulation of RNA biosynthetic process
BHE96_14495	COG2814	Major facilitator Superfamily
BHE96_14500	COG0656	L-ascorbic acid biosynthetic process
BHE96_14505	COG0237	dephospho-CoA kinase activity
BHE96_14510	COG1971	Probably functions as a manganese efflux pump
BHE96_14515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BHE96_14520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BHE96_14520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BHE96_14525	COG5002	protein histidine kinase activity
BHE96_14530	COG0745	RESPONSE REGULATOR receiver
BHE96_14540	COG0538	isocitrate dehydrogenase activity
BHE96_14545	COG0372	Belongs to the citrate synthase family
BHE96_14550	COG0457	Tetratricopeptide repeat
BHE96_14575	COG5632	N-Acetylmuramoyl-L-alanine amidase
BHE96_14585	COG0628	permease
BHE96_14590	COG3030	protein affecting phage T7 exclusion by the F plasmid
BHE96_14595	COG0469	pyruvate kinase activity
BHE96_14615	COG0281	malic enzyme
BHE96_14620	COG0587	DNA-directed DNA polymerase activity
BHE96_14640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BHE96_14650	COG4109	DRTGG domain
BHE96_14660	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_14675	COG0521	Mo-molybdopterin cofactor biosynthetic process
BHE96_14685	COG2801	Transposase and inactivated derivatives
BHE96_14695	COG0827	DNA restriction-modification system
BHE96_14700	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BHE96_14705	COG3874	Sporulation protein YtfJ
BHE96_14715	COG1714	RDD family
BHE96_14720	COG0616	signal peptide processing
BHE96_14725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BHE96_14730	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BHE96_14735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BHE96_14750	COG1104	cysteine desulfurase activity
BHE96_14755	COG1114	Component of the transport system for branched-chain amino acids
BHE96_14765	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BHE96_14770	COG1309	transcriptional regulator
BHE96_14775	COG1956	GAF domain-containing protein
BHE96_14780	COG2199	diguanylate cyclase activity
BHE96_14780	COG2203	Gaf domain
BHE96_14795	COG1012	belongs to the aldehyde dehydrogenase family
BHE96_14845	COG1017	nitric oxide dioxygenase activity
BHE96_14845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BHE96_14855	COG0693	protein deglycase activity
BHE96_14870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BHE96_14875	COG1378	Sugar-specific transcriptional regulator TrmB
BHE96_14900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BHE96_14905	COG0454	-acetyltransferase
BHE96_14910	COG0517	IMP dehydrogenase activity
BHE96_14915	COG0123	including yeast histone deacetylase and acetoin utilization protein
BHE96_14920	COG1360	Flagellar Motor Protein
BHE96_14925	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BHE96_14930	COG1609	Transcriptional regulator
BHE96_14935	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BHE96_14935	COG1605	Chorismate mutase
BHE96_14940	COG3118	belongs to the thioredoxin family
BHE96_14945	COG4980	gas vesicle protein
BHE96_14950	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BHE96_14960	COG1674	ftsk spoiiie
BHE96_14965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHE96_14975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHE96_14985	COG1363	Peptidase, m42
BHE96_14990	COG5584	Small secreted protein
BHE96_14995	COG0281	malic enzyme
BHE96_15000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHE96_15015	COG0510	thiamine kinase activity
BHE96_15020	COG1597	lipid kinase activity
BHE96_15030	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BHE96_15035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BHE96_15040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BHE96_15045	COG2252	PERMEase
BHE96_15050	COG4473	ABC transporter
BHE96_15055	COG1131	(ABC) transporter
BHE96_15060	COG1349	DNA-binding transcription factor activity
BHE96_15065	COG1187	pseudouridine synthase activity
BHE96_15070	COG2244	polysaccharide biosynthetic process
BHE96_15075	COG2081	HI0933 family
BHE96_15080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BHE96_15110	COG1486	melibiose metabolic process
BHE96_15120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHE96_15135	COG2202	Pas domain
BHE96_15135	COG1366	Belongs to the anti-sigma-factor antagonist family
BHE96_15140	COG2814	Major facilitator Superfamily
BHE96_15145	COG5522	Integral membrane protein (intg_mem_TP0381)
BHE96_15150	COG0577	efflux transmembrane transporter activity
BHE96_15155	COG1136	(ABC) transporter
BHE96_15160	COG2205	protein histidine kinase activity
BHE96_15165	COG0745	RESPONSE REGULATOR receiver
BHE96_15170	COG0577	efflux transmembrane transporter activity
BHE96_15175	COG1136	(ABC) transporter
BHE96_15195	COG1131	(ABC) transporter
BHE96_15200	COG1725	Transcriptional regulator
BHE96_15210	COG1242	4 iron, 4 sulfur cluster binding
BHE96_15215	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BHE96_15230	COG2267	carboxylic ester hydrolase activity
BHE96_15235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BHE96_15240	COG1113	amino acid transport
BHE96_15245	COG0367	asparagine synthase
BHE96_15265	COG1506	peptidase
BHE96_15270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BHE96_15275	COG1116	anion transmembrane transporter activity
BHE96_15280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BHE96_15285	COG0494	nUDIX hydrolase
BHE96_15290	COG4824	toxin secretion phage lysis holin
BHE96_15295	COG0783	Belongs to the Dps family
BHE96_15320	COG0288	reversible hydration of carbon dioxide
BHE96_15330	COG1271	oxidase subunit
BHE96_15335	COG1294	oxidase, subunit
BHE96_15350	COG4948	Mandelate Racemase Muconate Lactonizing
BHE96_15360	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BHE96_15365	COG0596	Alpha beta hydrolase
BHE96_15375	COG1169	isochorismate synthase
BHE96_15380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BHE96_15385	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BHE96_15510	COG3859	Proton-coupled thiamine transporter YuaJ
BHE96_15515	COG2268	Band 7 protein
BHE96_15520	COG1585	Membrane protein implicated in regulation of membrane protease activity
BHE96_15525	COG2318	DinB family
BHE96_15535	COG1454	alcohol dehydrogenase
BHE96_15545	COG1510	regulation of RNA biosynthetic process
BHE96_15555	COG0569	domain protein
BHE96_15560	COG1705	Flagellar rod assembly protein muramidase FlgJ
BHE96_15565	COG1017	nitric oxide dioxygenase activity
BHE96_15565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BHE96_15590	COG0628	permease
BHE96_15595	COG0673	inositol 2-dehydrogenase activity
BHE96_15600	COG0693	protein deglycase activity
BHE96_15605	COG0840	transmembrane signaling receptor activity
BHE96_15610	COG0840	transmembrane signaling receptor activity
BHE96_15615	COG0840	transmembrane signaling receptor activity
BHE96_15620	COG0840	transmembrane signaling receptor activity
BHE96_15635	COG2070	2-Nitropropane dioxygenase
BHE96_15640	COG0432	Pfam Uncharacterised protein family UPF0047
BHE96_15645	COG0366	Alpha amylase catalytic
BHE96_15650	COG1253	flavin adenine dinucleotide binding
BHE96_15655	COG2738	Putative neutral zinc metallopeptidase
BHE96_15670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BHE96_15700	COG1335	isochorismatase
BHE96_15705	COG1979	alcohol dehydrogenase
BHE96_15710	COG1979	alcohol dehydrogenase
BHE96_15715	COG2155	Conserved Protein
BHE96_15720	COG1098	S1 RNA binding domain
BHE96_15725	COG0436	Aminotransferase
BHE96_15730	COG1522	sequence-specific DNA binding
BHE96_15735	COG2267	carboxylic ester hydrolase activity
BHE96_15745	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BHE96_15750	COG2205	protein histidine kinase activity
BHE96_15760	COG5018	Exonuclease
BHE96_15765	COG2814	Major facilitator Superfamily
BHE96_15770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHE96_15775	COG3011	Protein conserved in bacteria
BHE96_15785	COG3290	protein histidine kinase activity
BHE96_15790	COG4565	transcriptional regulatory protein
BHE96_15820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BHE96_15820	COG2111	Na H antiporter
BHE96_15825	COG2111	Na H antiporter
BHE96_15830	COG1006	Multisubunit Na H antiporter MnhC subunit
BHE96_15835	COG0651	ATP synthesis coupled electron transport
BHE96_15840	COG1863	multisubunit Na H antiporter MnhE subunit
BHE96_15845	COG2212	antiporter activity
BHE96_15850	COG1320	monovalent cation:proton antiporter activity
BHE96_15855	COG2050	protein possibly involved in aromatic compounds catabolism
BHE96_15860	COG2197	response regulator
BHE96_15865	COG4585	Histidine kinase
BHE96_15895	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BHE96_15900	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BHE96_15905	COG1335	isochorismatase
BHE96_15910	COG5506	Protein of unknown function (DUF1694)
BHE96_15925	COG0628	permease
BHE96_15935	COG1418	mRNA catabolic process
BHE96_15940	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_15950	COG1511	domain protein
BHE96_15955	COG0433	COG0433 Predicted ATPase
BHE96_15955	COG1674	ftsk spoiiie
BHE96_15960	COG4499	WXG100 protein secretion system (Wss), protein YukC
BHE96_15965	COG5417	Belongs to the EsaB family
BHE96_15970	COG4842	Belongs to the WXG100 family
BHE96_15975	COG2508	Transcriptional regulator
BHE96_15975	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BHE96_15980	COG0686	Belongs to the AlaDH PNT family
BHE96_15985	COG5634	Uncharacterized conserved protein (DUF2278)
BHE96_15990	COG3251	PFAM MbtH domain protein
BHE96_15995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHE96_16000	COG1535	isochorismatase
BHE96_16000	COG3433	isochorismatase activity
BHE96_16005	COG1021	2,3-dihydroxybenzoate-AMP ligase
BHE96_16010	COG1169	isochorismate synthase
BHE96_16015	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_16020	COG2819	hydrolase of the alpha beta superfamily
BHE96_16025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BHE96_16030	COG1268	BioY protein
BHE96_16035	COG2056	Na+-H+ antiporter family
BHE96_16045	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BHE96_16050	COG3584	3D domain protein
BHE96_16060	COG1252	NADH dehydrogenase
BHE96_16090	COG1131	(ABC) transporter
BHE96_16115	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BHE96_16120	COG0316	Belongs to the HesB IscA family
BHE96_16130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHE96_16140	COG1252	NADH dehydrogenase
BHE96_16145	COG4837	Protein of unknown function (DUF1462)
BHE96_16150	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BHE96_16155	COG1506	peptidase
BHE96_16155	COG4946	Tricorn protease homolog
BHE96_16155	COG0823	Involved in the tonB-independent uptake of proteins
BHE96_16165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BHE96_16170	COG0460	homoserine dehydrogenase
BHE96_16175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BHE96_16180	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BHE96_16185	COG0647	UMP catabolic process
BHE96_16190	COG2445	Protein of unknown function DUF86
BHE96_16195	COG4470	Protein conserved in bacteria
BHE96_16210	COG0739	heme binding
BHE96_16220	COG0737	Belongs to the 5'-nucleotidase family
BHE96_16225	COG0730	response to heat
BHE96_16230	COG1801	Protein of unknown function DUF72
BHE96_16245	COG2508	Transcriptional regulator
BHE96_16250	COG0457	Tetratricopeptide repeat
BHE96_16255	COG2801	Transposase and inactivated derivatives
BHE96_16275	COG2814	Major facilitator Superfamily
BHE96_16280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BHE96_16285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BHE96_16290	COG2356	endonuclease I
BHE96_16295	COG3842	ATPase activity
BHE96_16300	COG2188	Transcriptional regulator
BHE96_16305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHE96_16310	COG0395	ABC-type sugar transport system, permease component
BHE96_16315	COG1175	transmembrane transport
BHE96_16320	COG1653	transport
BHE96_16325	COG2222	sugar isomerase
BHE96_16330	COG0789	Transcriptional regulator
BHE96_16355	COG0322	excinuclease ABC activity
BHE96_16360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHE96_16365	COG2226	methyltransferase
BHE96_16375	COG3409	Peptidoglycan-binding domain 1 protein
BHE96_16380	COG0719	Fe-S assembly protein
BHE96_16385	COG0822	iron-sulfur transferase activity
BHE96_16390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BHE96_16395	COG0719	Fe-S assembly protein
BHE96_16400	COG0396	ATPase activity
BHE96_16405	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BHE96_16410	COG1464	Belongs to the NlpA lipoprotein family
BHE96_16415	COG2011	ABC-type metal ion transport system permease component
BHE96_16420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BHE96_16430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHE96_16435	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BHE96_16450	COG1393	Belongs to the ArsC family
BHE96_16455	COG1960	acyl-CoA dehydrogenase activity
BHE96_16460	COG0183	Belongs to the thiolase family
BHE96_16465	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHE96_16465	COG1024	Enoyl-CoA hydratase
BHE96_16485	COG5577	PFAM Coat F domain
BHE96_16490	COG1846	Transcriptional regulator
BHE96_16495	COG0477	Major facilitator Superfamily
BHE96_16500	COG0583	DNA-binding transcription factor activity
BHE96_16520	COG1120	ATPase activity
BHE96_16535	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_16540	COG0783	Belongs to the Dps family
BHE96_16545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHE96_16550	COG0745	RESPONSE REGULATOR receiver
BHE96_16555	COG2205	protein histidine kinase activity
BHE96_16555	COG2770	Histidine kinase
BHE96_16560	COG1309	transcriptional regulator
BHE96_16565	COG0114	fumarate hydratase activity
BHE96_16575	COG0697	spore germination
BHE96_16580	COG0814	amino acid
BHE96_16590	COG2197	response regulator
BHE96_16595	COG4585	Histidine kinase
BHE96_16600	COG4758	membrane
BHE96_16605	COG3595	metallopeptidase activity
BHE96_16610	COG1842	Phage shock protein A
BHE96_16615	COG4758	membrane
BHE96_16620	COG2814	Major facilitator Superfamily
BHE96_16625	COG2096	Adenosyltransferase
BHE96_16630	COG1120	ATPase activity
BHE96_16635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHE96_16640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHE96_16645	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_16650	COG3386	PFAM SMP-30 Gluconolaconase
BHE96_16655	COG2205	protein histidine kinase activity
BHE96_16660	COG0745	RESPONSE REGULATOR receiver
BHE96_16670	COG1191	sigma factor activity
BHE96_16680	COG2140	Oxalate decarboxylase
BHE96_16690	COG1120	ATPase activity
BHE96_16695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHE96_16700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHE96_16705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHE96_16710	COG0531	amino acid
BHE96_16725	COG1988	membrane-bound metal-dependent
BHE96_16730	COG1368	sulfuric ester hydrolase activity
BHE96_16735	COG1910	domain protein
BHE96_16740	COG0725	ABC transporter, periplasmic molybdate-binding protein
BHE96_16745	COG4149	molybdate abc transporter
BHE96_16750	COG2197	response regulator
BHE96_16755	COG3850	Histidine kinase
BHE96_16760	COG1131	(ABC) transporter
BHE96_16770	COG0842	Transport permease protein
BHE96_16775	COG0656	L-ascorbic acid biosynthetic process
BHE96_16790	COG2801	Transposase and inactivated derivatives
BHE96_16810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BHE96_16815	COG3973	AAA domain
BHE96_16820	COG2860	membrane
BHE96_16830	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BHE96_16835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BHE96_16840	COG2217	Heavy metal translocating P-type atpase
BHE96_16845	COG2217	Heavy metal translocating P-type atpase
BHE96_16850	COG2608	mercury ion transmembrane transporter activity
BHE96_16855	COG1937	Protein conserved in bacteria
BHE96_16860	COG0673	inositol 2-dehydrogenase activity
BHE96_16880	COG2814	Major facilitator Superfamily
BHE96_16895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHE96_16900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BHE96_16905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHE96_16910	COG1126	abc transporter atp-binding protein
BHE96_16915	COG0765	amino acid transport
BHE96_16920	COG0765	amino acid transport
BHE96_16925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHE96_16930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHE96_16935	COG0454	-acetyltransferase
BHE96_16940	COG0583	DNA-binding transcription factor activity
BHE96_16950	COG2801	Transposase and inactivated derivatives
BHE96_16955	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_16975	COG0557	exoribonuclease II activity
BHE96_16980	COG1647	Serine aminopeptidase, S33
BHE96_16985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BHE96_16990	COG1476	TRANSCRIPTIONal
BHE96_16995	COG1396	sequence-specific DNA binding
BHE96_17000	COG1396	sequence-specific DNA binding
BHE96_17005	COG1733	regulation of RNA biosynthetic process
BHE96_17035	COG1174	glycine betaine transport
BHE96_17040	COG1732	Glycine betaine
BHE96_17045	COG1174	glycine betaine transport
BHE96_17050	COG1125	glycine betaine transport
BHE96_17050	COG0517	IMP dehydrogenase activity
BHE96_17055	COG1510	regulation of RNA biosynthetic process
BHE96_17060	COG1174	glycine betaine transport
BHE96_17065	COG1732	Glycine betaine
BHE96_17070	COG1174	glycine betaine transport
BHE96_17075	COG1125	glycine betaine transport
BHE96_17075	COG0517	IMP dehydrogenase activity
BHE96_17080	COG1510	regulation of RNA biosynthetic process
BHE96_17085	COG2095	MarC family integral membrane protein
BHE96_17095	COG3064	Membrane
BHE96_17100	COG4640	response to antibiotic
BHE96_17105	COG0456	acetyltransferase
BHE96_17120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BHE96_17135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BHE96_17140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHE96_17145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BHE96_17155	COG2234	aminopeptidase activity
BHE96_17175	COG0126	phosphoglycerate kinase activity
BHE96_17185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BHE96_17190	COG2390	Transcriptional regulator
BHE96_17195	COG2814	Major facilitator Superfamily
BHE96_17200	COG1609	Transcriptional regulator
BHE96_17205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHE96_17215	COG0583	DNA-binding transcription factor activity
BHE96_17220	COG0697	spore germination
BHE96_17225	COG1113	amino acid transport
BHE96_17235	COG1609	Transcriptional regulator
BHE96_17245	COG0561	phosphatase activity
BHE96_17250	COG1737	Transcriptional regulator
BHE96_17255	COG1070	Carbohydrate kinase
BHE96_17280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHE96_17285	COG2186	Transcriptional regulator
BHE96_17290	COG1620	l-lactate permease
BHE96_17295	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BHE96_17305	COG5039	Polysaccharide pyruvyl transferase
BHE96_17310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BHE96_17315	COG0110	maltose O-acetyltransferase activity
BHE96_17320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BHE96_17325	COG2244	polysaccharide biosynthetic process
BHE96_17330	COG1216	Glycosyl transferase, family 2
BHE96_17335	COG5039	Polysaccharide pyruvyl transferase
BHE96_17340	COG1216	Glycosyl transferase, family 2
BHE96_17350	COG0438	transferase activity, transferring glycosyl groups
BHE96_17355	COG1215	transferase activity, transferring glycosyl groups
BHE96_17360	COG0438	transferase activity, transferring glycosyl groups
BHE96_17365	COG1086	Polysaccharide biosynthesis protein
BHE96_17370	COG0489	protein tyrosine kinase activity
BHE96_17375	COG3944	biosynthesis protein
BHE96_17380	COG1396	sequence-specific DNA binding
BHE96_17385	COG2272	Belongs to the type-B carboxylesterase lipase family
BHE96_17395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BHE96_17400	COG2364	Membrane
BHE96_17405	COG0456	acetyltransferase
BHE96_17410	COG3479	Phenolic acid decarboxylase
BHE96_17455	COG2223	nitrite transmembrane transporter activity
BHE96_17460	COG1609	Transcriptional regulator
BHE96_17470	COG0583	DNA-binding transcription factor activity
BHE96_17475	COG2828	Protein conserved in bacteria
BHE96_17480	COG0477	Major facilitator Superfamily
BHE96_17480	COG2814	Major facilitator Superfamily
BHE96_17485	COG1611	Belongs to the LOG family
BHE96_17490	COG1694	Mazg nucleotide pyrophosphohydrolase
BHE96_17495	COG0659	secondary active sulfate transmembrane transporter activity
BHE96_17500	COG0288	reversible hydration of carbon dioxide
BHE96_17510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHE96_17515	COG4290	ribonuclease
BHE96_17520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BHE96_17530	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BHE96_17535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHE96_17545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BHE96_17555	COG1051	belongs to the nudix hydrolase family
BHE96_17560	COG0492	ferredoxin-NADP+ reductase activity
BHE96_17565	COG3883	PFAM NLP P60 protein
BHE96_17565	COG0791	NLP P60 protein
BHE96_17570	COG0457	Tetratricopeptide repeat
BHE96_17575	COG5002	protein histidine kinase activity
BHE96_17580	COG0745	RESPONSE REGULATOR receiver
BHE96_17585	COG1132	(ABC) transporter
BHE96_17590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BHE96_17590	COG0140	phosphoribosyl-ATP diphosphatase activity
BHE96_17615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BHE96_17630	COG4990	cell redox homeostasis
BHE96_17635	COG0110	maltose O-acetyltransferase activity
BHE96_17655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BHE96_17670	COG1309	transcriptional regulator
BHE96_17675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BHE96_17680	COG1950	PFAM Membrane protein of
BHE96_17685	COG1983	PspC domain protein
BHE96_17690	COG3595	metallopeptidase activity
BHE96_17705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BHE96_17715	COG4897	Protein conserved in bacteria
BHE96_17720	COG3848	Pyruvate phosphate dikinase
BHE96_17720	COG0574	Belongs to the PEP-utilizing enzyme family
BHE96_17725	COG1309	transcriptional regulator
BHE96_17730	COG2814	Major facilitator Superfamily
BHE96_17740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHE96_17750	COG0793	Belongs to the peptidase S41A family
BHE96_17750	COG3409	Peptidoglycan-binding domain 1 protein
BHE96_17755	COG3420	alginic acid biosynthetic process
BHE96_17760	COG2177	Part of the ABC transporter FtsEX involved in
BHE96_17765	COG2884	Cell division ATP-binding protein ftsE
BHE96_17770	COG2010	Cytochrome c
BHE96_17775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHE96_17780	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BHE96_17785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BHE96_17795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BHE96_17810	COG1516	flagellar protein fliS
BHE96_17815	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BHE96_17820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BHE96_17840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BHE96_17845	COG1256	bacterial-type flagellum assembly
BHE96_17845	COG4786	Flagellar basal body rod
BHE96_17850	COG3418	PFAM FlgN family protein
BHE96_17855	COG2747	anti-sigma28 factor FlgM
BHE96_17865	COG1040	competence protein
BHE96_17875	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BHE96_17880	COG1307	EDD domain protein, DegV family
BHE96_17885	COG2197	response regulator
BHE96_17895	COG1739	Uncharacterized protein family UPF0029
BHE96_17900	COG1316	TRANSCRIPTIONal
BHE96_17905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BHE96_17910	COG0438	transferase activity, transferring glycosyl groups
BHE96_17915	COG1215	transferase activity, transferring glycosyl groups
BHE96_17920	COG3206	protein involved in exopolysaccharide biosynthesis
BHE96_17925	COG3307	-O-antigen
BHE96_17930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BHE96_17935	COG0438	transferase activity, transferring glycosyl groups
BHE96_17935	COG0297	glycogen (starch) synthase activity
BHE96_17940	COG2244	polysaccharide biosynthetic process
BHE96_17950	COG2247	cell wall binding repeat
BHE96_17950	COG0860	N-Acetylmuramoyl-L-alanine amidase
BHE96_17955	COG2247	cell wall binding repeat
BHE96_17955	COG2385	sporulation resulting in formation of a cellular spore
BHE96_17965	COG1316	TRANSCRIPTIONal
BHE96_17970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BHE96_17975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BHE96_17980	COG1134	teichoic acid transport
BHE96_17985	COG1682	transport, permease protein
BHE96_17990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BHE96_17995	COG0438	transferase activity, transferring glycosyl groups
BHE96_18000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BHE96_18005	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BHE96_18010	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BHE96_18015	COG4193	domain, Protein
BHE96_18020	COG1482	cell wall glycoprotein biosynthetic process
BHE96_18025	COG0697	spore germination
BHE96_18030	COG0814	amino acid
BHE96_18040	COG1215	transferase activity, transferring glycosyl groups
BHE96_18045	COG2814	Major facilitator Superfamily
BHE96_18050	COG1316	TRANSCRIPTIONal
BHE96_18055	COG0561	phosphatase activity
BHE96_18060	COG2433	Pfam Transposase IS66
BHE96_18065	COG0791	NLP P60 protein
BHE96_18070	COG2843	Capsule synthesis protein
BHE96_18080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BHE96_18090	COG0697	spore germination
BHE96_18095	COG0814	amino acid
BHE96_18105	COG1609	Transcriptional regulator
BHE96_18110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHE96_18120	COG1129	ABC transporter
BHE96_18125	COG1172	Belongs to the binding-protein-dependent transport system permease family
BHE96_18130	COG1879	ABC-type sugar transport system periplasmic component
BHE96_18135	COG3103	Sh3 type 3 domain protein
BHE96_18140	COG2249	NAD(P)H dehydrogenase (quinone) activity
BHE96_18145	COG3527	Alpha-acetolactate decarboxylase
BHE96_18150	COG0028	Belongs to the TPP enzyme family
BHE96_18155	COG0583	DNA-binding transcription factor activity
BHE96_18160	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BHE96_18175	COG5337	Spore coat protein CotH
BHE96_18185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BHE96_18195	COG0405	Gamma-glutamyltransferase
BHE96_18200	COG1522	sequence-specific DNA binding
BHE96_18205	COG2059	Chromate
BHE96_18210	COG2059	Chromate
BHE96_18255	COG5444	nuclease activity
BHE96_18270	COG3878	Protein conserved in bacteria
BHE96_18275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BHE96_18280	COG4464	protein tyrosine phosphatase activity
BHE96_18285	COG0489	protein tyrosine kinase activity
BHE96_18290	COG3944	biosynthesis protein
BHE96_18300	COG4715	Zinc finger, swim domain protein
BHE96_18305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BHE96_18310	COG0561	phosphatase activity
BHE96_18315	COG1349	DNA-binding transcription factor activity
BHE96_18320	COG0629	single-stranded DNA binding
BHE96_18345	COG0457	Tetratricopeptide repeat
BHE96_18350	COG4786	Flagellar basal body rod
BHE96_18355	COG4786	Flagellar basal body rod
BHE96_18360	COG1077	Cell shape determining protein MreB Mrl
BHE96_18365	COG1609	Transcriptional regulator
BHE96_18370	COG1846	Transcriptional regulator
BHE96_18375	COG2814	Major facilitator Superfamily
BHE96_18380	COG1953	Uracil, thiamine, allantoin
BHE96_18385	COG0477	Major facilitator Superfamily
BHE96_18390	COG1335	isochorismatase
BHE96_18395	COG0004	ammonium transporteR
BHE96_18400	COG0347	Belongs to the P(II) protein family
BHE96_18405	COG0772	Belongs to the SEDS family
BHE96_18410	COG0671	phosphoesterase, PA-phosphatase related
BHE96_18420	COG0739	heme binding
BHE96_18425	COG1247	-acetyltransferase
BHE96_18440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHE96_18455	COG0726	polysaccharide deacetylase
BHE96_18465	COG1959	2 iron, 2 sulfur cluster binding
BHE96_18480	COG0831	urea catabolic process
BHE96_18485	COG3237	CsbD-like
BHE96_18490	COG1994	Peptidase M50
BHE96_18495	COG0457	Tetratricopeptide repeat
BHE96_18505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BHE96_18510	COG2304	oxidoreductase activity
BHE96_18515	COG2304	oxidoreductase activity
BHE96_18520	COG2385	sporulation resulting in formation of a cellular spore
BHE96_18525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BHE96_18535	COG4836	Membrane
BHE96_18575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BHE96_18605	COG0698	ribose 5-phosphate isomerase
BHE96_18610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BHE96_18620	COG0009	L-threonylcarbamoyladenylate synthase
BHE96_18625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BHE96_18645	COG2890	protein-(glutamine-N5) methyltransferase activity
BHE96_18650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BHE96_18655	COG0346	lactoylglutathione lyase activity
BHE96_18660	COG0789	Transcriptional regulator
BHE96_18665	COG0679	Auxin Efflux Carrier
BHE96_18670	COG0281	malic enzyme
BHE96_18680	COG0254	rRNA binding
BHE96_18685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BHE96_18690	COG1494	fructose-1,6-bisphosphatase
BHE96_18695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BHE96_18705	COG0191	fructose-bisphosphate aldolase activity
BHE96_18710	COG2204	response regulator
BHE96_18715	COG4821	SIS domain
BHE96_18730	COG0247	lactate metabolic process
BHE96_18730	COG2181	nitrate reductase activity
BHE96_18735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHE96_18750	COG1132	(ABC) transporter
BHE96_18765	COG2181	nitrate reductase activity
BHE96_18770	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BHE96_18775	COG1140	nitrate reductase beta subunit
BHE96_18780	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BHE96_18785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHE96_18795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHE96_18800	COG2223	nitrite transmembrane transporter activity
BHE96_18810	COG4506	Protein conserved in bacteria
BHE96_18820	COG3391	amine dehydrogenase activity
BHE96_18825	COG3391	amine dehydrogenase activity
BHE96_18835	COG0457	Tetratricopeptide repeat
BHE96_18880	COG0010	Belongs to the arginase family
BHE96_18885	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BHE96_18890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHE96_18905	COG1994	Peptidase M50
BHE96_18910	COG1942	4-Oxalocrotonate Tautomerase
BHE96_18915	COG1846	Transcriptional regulator
BHE96_18925	COG0531	amino acid
BHE96_18930	COG3465	dGTPase activity
BHE96_18935	COG1078	dGTPase activity
BHE96_18950	COG1695	Transcriptional regulator
BHE96_18960	COG1131	(ABC) transporter
BHE96_18965	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BHE96_18995	COG0583	DNA-binding transcription factor activity
BHE96_19000	COG2855	membrane
BHE96_19005	COG0280	phosphate acetyltransferase
BHE96_19015	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_19020	COG0436	Aminotransferase
BHE96_19050	COG2814	Major facilitator Superfamily
BHE96_19055	COG2814	Major facilitator Superfamily
BHE96_19060	COG0833	amino acid
BHE96_19065	COG4187	Peptidase family M20/M25/M40
BHE96_19070	COG1012	belongs to the aldehyde dehydrogenase family
BHE96_19075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BHE96_19080	COG2205	protein histidine kinase activity
BHE96_19085	COG0745	RESPONSE REGULATOR receiver
BHE96_19100	COG1131	(ABC) transporter
BHE96_19110	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BHE96_19115	COG1091	dTDP-4-dehydrorhamnose reductase activity
BHE96_19120	COG1088	dTDP-glucose 4,6-dehydratase activity
BHE96_19125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BHE96_19130	COG3980	spore coat polysaccharide biosynthesis protein
BHE96_19135	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BHE96_19140	COG2089	acid synthase
BHE96_19145	COG0456	acetyltransferase
BHE96_19150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BHE96_19155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BHE96_19160	COG0463	Glycosyl transferase, family 2
BHE96_19170	COG2363	Small membrane protein
BHE96_19175	COG2233	PERMEase
BHE96_19190	COG1216	Glycosyl transferase, family 2
BHE96_19205	COG1695	Transcriptional regulator
BHE96_19210	COG0351	phosphomethylpyrimidine kinase
BHE96_19220	COG1621	beta-fructofuranosidase activity
BHE96_19225	COG1263	PTS System
BHE96_19225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHE96_19230	COG3711	transcriptional antiterminator
BHE96_19240	COG1404	Belongs to the peptidase S8 family
BHE96_19245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHE96_19250	COG0778	Nitroreductase
BHE96_19255	COG0772	Belongs to the SEDS family
BHE96_19260	COG0454	-acetyltransferase
BHE96_19280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BHE96_19285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BHE96_19290	COG2261	transglycosylase associated protein
BHE96_19295	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BHE96_19300	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BHE96_19305	COG2246	polysaccharide biosynthetic process
BHE96_19310	COG1309	transcriptional regulator
BHE96_19330	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BHE96_19335	COG2837	iron assimilation
BHE96_19340	COG2822	iron ion transport
BHE96_19355	COG0583	DNA-binding transcription factor activity
BHE96_19365	COG1346	cytolysis
BHE96_19370	COG4895	conserved protein (DUF2196)
BHE96_19375	COG0789	Transcriptional regulator
BHE96_19380	COG5504	Zn-dependent protease
BHE96_19385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BHE96_19390	COG0346	lactoylglutathione lyase activity
BHE96_19395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHE96_19400	COG1404	Belongs to the peptidase S8 family
BHE96_19405	COG1442	glycosyl transferase family 8
BHE96_19415	COG2357	RelA SpoT domain protein
BHE96_19420	COG1575	Belongs to the MenA family. Type 1 subfamily
BHE96_19440	COG1696	Membrane protein involved in D-alanine export
BHE96_19450	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BHE96_19455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BHE96_19460	COG1486	melibiose metabolic process
BHE96_19465	COG1447	Phosphotransferase system cellobiose-specific component IIA
BHE96_19470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHE96_19475	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHE96_19480	COG3711	transcriptional antiterminator
BHE96_19480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHE96_19495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHE96_19500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHE96_19510	COG0640	Transcriptional regulator
BHE96_19515	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BHE96_19520	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHE96_19525	COG1447	Phosphotransferase system cellobiose-specific component IIA
BHE96_19530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHE96_19535	COG2723	6-phospho-beta-galactosidase activity
BHE96_19540	COG1940	carbohydrate kinase activity
BHE96_19545	COG1482	cell wall glycoprotein biosynthetic process
BHE96_19555	COG0753	catalase activity
BHE96_19560	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BHE96_19565	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BHE96_19570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BHE96_19575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BHE96_19580	COG4988	ABC transporter
BHE96_19585	COG1294	oxidase, subunit
BHE96_19590	COG1271	oxidase subunit
BHE96_19595	COG3493	citrate carrier protein
BHE96_19600	COG0726	polysaccharide deacetylase
BHE96_19605	COG3842	ATPase activity
BHE96_19610	COG2508	Transcriptional regulator
BHE96_19615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHE96_19625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BHE96_19635	COG4894	glucomannan catabolic process
BHE96_19640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BHE96_19645	COG0500	methyltransferase
BHE96_19650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHE96_19665	COG0693	protein deglycase activity
BHE96_19665	COG0753	catalase activity
BHE96_19670	COG2851	Citrate transporter
BHE96_19675	COG2273	Hydrolase Family 16
BHE96_19680	COG3711	transcriptional antiterminator
BHE96_19685	COG2270	Major facilitator Superfamily
BHE96_19690	COG0513	Belongs to the DEAD box helicase family
BHE96_19780	COG0697	spore germination
BHE96_19785	COG0589	response to stress
BHE96_19790	COG2723	6-phospho-beta-galactosidase activity
BHE96_19795	COG2190	(PTS) system
BHE96_19795	COG1263	PTS System
BHE96_19795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHE96_19805	COG0494	nUDIX hydrolase
BHE96_19810	COG3507	Belongs to the glycosyl hydrolase 43 family
BHE96_19835	COG0010	Belongs to the arginase family
BHE96_19840	COG0833	amino acid
BHE96_19845	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BHE96_19850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHE96_19860	COG2390	Transcriptional regulator
BHE96_19865	COG0561	phosphatase activity
BHE96_19895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHE96_19900	COG5294	Protein conserved in bacteria
BHE96_19905	COG0577	efflux transmembrane transporter activity
BHE96_19910	COG1136	(ABC) transporter
BHE96_19915	COG2205	protein histidine kinase activity
BHE96_19920	COG0745	RESPONSE REGULATOR receiver
BHE96_19935	COG1082	Xylose isomerase domain protein TIM barrel
BHE96_19945	COG2814	Major facilitator Superfamily
BHE96_19975	COG1349	DNA-binding transcription factor activity
BHE96_19980	COG0667	Aldo Keto reductase
BHE96_19985	COG2814	Major facilitator Superfamily
BHE96_20000	COG1028	Short-chain dehydrogenase reductase Sdr
BHE96_20005	COG2197	response regulator
BHE96_20010	COG4585	Histidine kinase
BHE96_20015	COG3239	Fatty acid desaturase
BHE96_20025	COG1309	transcriptional regulator
BHE96_20030	COG1012	belongs to the aldehyde dehydrogenase family
BHE96_20035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHE96_20045	COG0640	Transcriptional regulator
BHE96_20050	COG2814	Major facilitator Superfamily
BHE96_20055	COG1714	RDD family
BHE96_20065	COG0450	alkyl hydroperoxide reductase
BHE96_20070	COG3634	alkyl hydroperoxide reductase activity
BHE96_20075	COG3177	Filamentation induced by cAMP protein fic
BHE96_20080	COG1113	amino acid transport
BHE96_20090	COG2080	2 iron, 2 sulfur cluster binding
BHE96_20105	COG2068	MobA-Related Protein
BHE96_20110	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BHE96_20160	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BHE96_20165	COG0667	Aldo Keto reductase
BHE96_20170	COG0456	acetyltransferase
BHE96_20175	COG0457	Tetratricopeptide repeat
BHE96_20180	COG0010	Belongs to the arginase family
BHE96_20185	COG0833	amino acid
BHE96_20190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BHE96_20195	COG5658	integral membrane protein
BHE96_20200	COG0640	Transcriptional regulator
BHE96_20205	COG3829	transcription factor binding
BHE96_20215	COG0488	(ABC) transporter
BHE96_20230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BHE96_20235	COG5002	protein histidine kinase activity
BHE96_20235	COG3850	Histidine kinase
BHE96_20240	COG0745	RESPONSE REGULATOR receiver
BHE96_20245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHE96_20250	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BHE96_20255	COG4853	Protein conserved in bacteria
BHE96_20260	COG4863	YycH protein
BHE96_20265	COG5002	protein histidine kinase activity
BHE96_20270	COG0745	RESPONSE REGULATOR receiver
BHE96_20305	COG0346	lactoylglutathione lyase activity
BHE96_20310	COG0305	Participates in initiation and elongation during chromosome replication
BHE96_20330	COG3093	addiction module antidote protein HigA
BHE96_20335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BHE96_20350	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BHE96_20355	COG0438	transferase activity, transferring glycosyl groups
BHE96_20375	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BHE96_20380	COG4241	membrane
BHE96_20385	COG5577	PFAM Coat F domain
BHE96_20390	COG1733	regulation of RNA biosynthetic process
BHE96_20400	COG0697	spore germination
BHE96_20405	COG1621	beta-fructofuranosidase activity
BHE96_20410	COG1621	beta-fructofuranosidase activity
BHE96_20415	COG1802	Transcriptional regulator
BHE96_20420	COG2318	DinB family
BHE96_20425	COG2211	Major facilitator Superfamily
BHE96_20430	COG0583	DNA-binding transcription factor activity
BHE96_20445	COG0583	DNA-binding transcription factor activity
BHE96_20455	COG0778	Nitroreductase
BHE96_20460	COG1846	Transcriptional regulator
BHE96_20465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHE96_20470	COG1846	Transcriptional regulator
BHE96_20475	COG2153	protein acetylation
BHE96_20485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BHE96_20490	COG0583	DNA-binding transcription factor activity
BHE96_20510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHE96_20515	COG0697	spore germination
BHE96_20520	COG1331	Highly conserved protein containing a thioredoxin domain
BHE96_20525	COG1266	CAAX protease self-immunity
BHE96_20530	COG2814	Major facilitator Superfamily
BHE96_20530	COG0477	Major facilitator Superfamily
BHE96_20535	COG0346	lactoylglutathione lyase activity
BHE96_20540	COG1609	Transcriptional regulator
BHE96_20545	COG0708	Exodeoxyribonuclease III
BHE96_20550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BHE96_20555	COG2169	Transcriptional regulator
BHE96_20565	COG0629	single-stranded DNA binding
BHE96_20575	COG0012	GTP binding
BHE96_20580	COG0243	molybdopterin cofactor binding
BHE96_20585	COG4481	Protein conserved in bacteria
BHE96_20590	COG3949	Membrane
BHE96_20605	COG1475	DNA binding
BHE96_20610	COG1192	Involved in chromosome partitioning
BHE96_20635	COG1847	R3H domain protein
BHE96_20640	COG0706	membrane insertase activity
BHE96_20650	COG0230	Belongs to the bacterial ribosomal protein bL34 family
