locus-tag	class	description
ORP33_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ORP33_00010	COG0592	DNA-directed DNA polymerase activity
ORP33_00015	COG2501	S4 domain
ORP33_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ORP33_00030	COG0187	DNA topoisomerase II activity
ORP33_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ORP33_00070	COG0516	GMP reductase activity
ORP33_00070	COG0517	IMP dehydrogenase activity
ORP33_00075	COG1686	Belongs to the peptidase S11 family
ORP33_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ORP33_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ORP33_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ORP33_00100	COG1428	Deoxynucleoside kinase
ORP33_00105	COG1428	Deoxynucleoside kinase
ORP33_00110	COG1388	LysM domain
ORP33_00110	COG3858	chitin binding
ORP33_00115	COG1335	isochorismatase
ORP33_00120	COG0590	tRNA wobble adenosine to inosine editing
ORP33_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ORP33_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ORP33_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ORP33_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
ORP33_00190	COG3853	Toxic anion resistance protein (TelA)
ORP33_00195	COG1982	Orn Lys Arg decarboxylase major
ORP33_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ORP33_00205	COG3870	Protein conserved in bacteria
ORP33_00210	COG1728	Protein conserved in bacteria
ORP33_00215	COG0470	DNA polymerase III
ORP33_00220	COG1774	PSP1 C-terminal conserved region
ORP33_00225	COG4467	Involved in initiation control of chromosome replication
ORP33_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ORP33_00235	COG2827	Endonuclease containing a URI domain
ORP33_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ORP33_00245	COG2002	toxin-antitoxin pair type II binding
ORP33_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ORP33_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ORP33_00255	COG0084	hydrolase, TatD family'
ORP33_00260	COG3583	domain protein
ORP33_00260	COG3584	3D domain protein
ORP33_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ORP33_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ORP33_00280	COG4466	Protein conserved in bacteria
ORP33_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ORP33_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ORP33_00300	COG0251	oxidation-reduction process
ORP33_00305	COG2088	sporulation resulting in formation of a cellular spore
ORP33_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ORP33_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ORP33_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ORP33_00325	COG0193	aminoacyl-tRNA hydrolase activity
ORP33_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ORP33_00340	COG2002	toxin-antitoxin pair type II binding
ORP33_00345	COG2244	polysaccharide biosynthetic process
ORP33_00350	COG3956	TIGRFAM MazG family protein
ORP33_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ORP33_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ORP33_00375	COG1098	S1 RNA binding domain
ORP33_00390	COG2208	phosphoserine phosphatase activity
ORP33_00395	COG2304	oxidoreductase activity
ORP33_00400	COG0515	serine threonine protein kinase
ORP33_00405	COG0037	tRNA processing
ORP33_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ORP33_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ORP33_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ORP33_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ORP33_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ORP33_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ORP33_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ORP33_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
ORP33_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ORP33_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ORP33_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ORP33_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ORP33_00470	COG1396	sequence-specific DNA binding
ORP33_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ORP33_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ORP33_00560	COG4463	regulation of RNA biosynthetic process
ORP33_00565	COG3880	PFAM UvrB UvrC protein
ORP33_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ORP33_00575	COG0542	response to heat
ORP33_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ORP33_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ORP33_00590	COG4956	integral membrane protein (PIN domain superfamily)
ORP33_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ORP33_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ORP33_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ORP33_00610	COG1045	serine acetyltransferase
ORP33_00615	COG0215	cysteine-tRNA ligase activity
ORP33_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ORP33_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ORP33_00630	COG3688	RNA-binding protein containing a PIN domain
ORP33_00635	COG1595	DNA-templated transcription, initiation
ORP33_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ORP33_00650	COG0250	Participates in transcription elongation, termination and antitermination
ORP33_00660	COG0081	regulation of translation
ORP33_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ORP33_00675	COG2813	Specifically methylates the guanine in position
ORP33_00680	COG0085	RNA polymerase activity
ORP33_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ORP33_00690	COG1358	cellular component organization or biogenesis
ORP33_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ORP33_00700	COG0049	tRNA binding
ORP33_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ORP33_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ORP33_00715	COG0596	Alpha beta hydrolase
ORP33_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ORP33_00730	COG0088	Forms part of the polypeptide exit tunnel
ORP33_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ORP33_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ORP33_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ORP33_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ORP33_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ORP33_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ORP33_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ORP33_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ORP33_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ORP33_00820	COG0200	Binds to the 23S rRNA
ORP33_00825	COG0201	protein transport
ORP33_00830	COG0563	adenylate kinase activity
ORP33_00835	COG0024	Methionine aminopeptidase
ORP33_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
ORP33_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ORP33_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ORP33_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ORP33_00865	COG0202	RNA polymerase activity
ORP33_00870	COG0203	ribosomal protein L17
ORP33_00875	COG1122	ATPase activity
ORP33_00880	COG1122	ATPase activity
ORP33_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ORP33_00890	COG0101	tRNA pseudouridine synthase activity
ORP33_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ORP33_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ORP33_00905	COG2226	methyltransferase
ORP33_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
ORP33_00920	COG0489	protein tyrosine kinase activity
ORP33_00930	COG2194	sulfuric ester hydrolase activity
ORP33_00935	COG0726	polysaccharide deacetylase
ORP33_01020	COG0659	secondary active sulfate transmembrane transporter activity
ORP33_01025	COG0385	Bile acid
ORP33_01030	COG2819	hydrolase of the alpha beta superfamily
ORP33_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ORP33_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ORP33_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ORP33_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ORP33_01050	COG2207	Transcriptional regulator
ORP33_01055	COG3876	Protein conserved in bacteria
ORP33_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
ORP33_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ORP33_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ORP33_01070	COG1263	PTS System
ORP33_01075	COG1737	Transcriptional regulator
ORP33_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ORP33_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ORP33_01090	COG1683	Conserved Protein
ORP33_01120	COG1595	DNA-templated transcription, initiation
ORP33_01125	COG5662	AntiSigma factor
ORP33_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ORP33_01135	COG4856	YbbR-like protein
ORP33_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ORP33_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ORP33_01150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ORP33_01155	COG2169	Transcriptional regulator
ORP33_01160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ORP33_01165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ORP33_01170	COG3002	Belongs to the UPF0753 family
ORP33_01175	COG0288	reversible hydration of carbon dioxide
ORP33_01185	COG5609	conserved protein (DUF2294)
ORP33_01190	COG0640	Transcriptional regulator
ORP33_01195	COG2814	Major facilitator Superfamily
ORP33_01220	COG1136	(ABC) transporter
ORP33_01245	COG1113	amino acid transport
ORP33_01260	COG2602	Beta-lactamase
ORP33_01265	COG2124	cytochrome p450
ORP33_01275	COG0531	amino acid
ORP33_01280	COG0584	glycerophosphoryl diester phosphodiesterase
ORP33_01285	COG2271	Major facilitator Superfamily
ORP33_01295	COG0456	acetyltransferase
ORP33_01295	COG1846	Transcriptional regulator
ORP33_01300	COG2271	Major facilitator Superfamily
ORP33_01310	COG3409	Peptidoglycan-binding domain 1 protein
ORP33_01315	COG0697	spore germination
ORP33_01320	COG1917	Cupin 2, conserved barrel domain protein
ORP33_01320	COG2207	Transcriptional regulator
ORP33_01325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ORP33_01330	COG3591	Belongs to the peptidase S1B family
ORP33_01340	COG0596	Alpha beta hydrolase
ORP33_01345	COG1183	phosphatidylcholine synthase activity
ORP33_01350	COG0586	Pfam SNARE associated Golgi protein
ORP33_01355	COG0688	phosphatidylethanolamine metabolic process
ORP33_01365	COG2312	Erythromycin esterase
ORP33_01370	COG2207	Transcriptional regulator
ORP33_01375	COG1054	Belongs to the UPF0176 family
ORP33_01380	COG1301	dicarboxylic acid transport
ORP33_01385	COG2190	(PTS) system
ORP33_01385	COG1263	PTS System
ORP33_01385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ORP33_01390	COG0363	glucosamine-6-phosphate deaminase activity
ORP33_01395	COG2188	Transcriptional regulator
ORP33_01405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ORP33_01410	COG0833	amino acid
ORP33_01415	COG2040	homocysteine
ORP33_01420	COG1115	amino acid carrier protein
ORP33_01425	COG2066	Belongs to the glutaminase family
ORP33_01430	COG4191	Histidine kinase
ORP33_01435	COG0784	Response regulator, receiver
ORP33_01440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ORP33_01445	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_01450	COG2271	Major facilitator Superfamily
ORP33_01455	COG4948	Mandelate Racemase Muconate Lactonizing
ORP33_01460	COG2186	Transcriptional regulator
ORP33_01465	COG2721	sulfolactate sulfo-lyase activity
ORP33_01470	COG3173	Aminoglycoside phosphotransferase
ORP33_01480	COG0697	spore germination
ORP33_01485	COG0745	RESPONSE REGULATOR receiver
ORP33_01490	COG2205	protein histidine kinase activity
ORP33_01495	COG1131	(ABC) transporter
ORP33_01510	COG3773	Cell wall hydrolase
ORP33_01515	COG2304	oxidoreductase activity
ORP33_01520	COG3540	Alkaline phosphatase
ORP33_01525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ORP33_01530	COG0805	protein transport
ORP33_01535	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ORP33_01540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ORP33_01545	COG0477	Major facilitator Superfamily
ORP33_01550	COG1309	transcriptional regulator
ORP33_01555	COG0252	asparaginase activity
ORP33_01560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ORP33_01565	COG1714	RDD family
ORP33_01570	COG3012	SEC-C Motif Domain Protein
ORP33_01570	COG1405	negative regulation of cell septum assembly
ORP33_01575	COG3290	protein histidine kinase activity
ORP33_01580	COG3279	Response regulator of the LytR AlgR family
ORP33_01585	COG4555	ABC transporter
ORP33_01590	COG1668	transmembrane transport
ORP33_01595	COG0667	Aldo Keto reductase
ORP33_01605	COG1595	DNA-templated transcription, initiation
ORP33_01610	COG1595	DNA-templated transcription, initiation
ORP33_01615	COG1876	peptidase activity
ORP33_01620	COG0457	Tetratricopeptide repeat
ORP33_01625	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_01630	COG0366	Alpha amylase catalytic
ORP33_01635	COG0803	Belongs to the bacterial solute-binding protein 9 family
ORP33_01640	COG1121	(ABC) transporter
ORP33_01645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ORP33_01650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ORP33_01655	COG2310	stress, protein
ORP33_01660	COG2310	stress, protein
ORP33_01665	COG2310	stress, protein
ORP33_01670	COG0861	Integral membrane protein TerC family
ORP33_01680	COG3853	Toxic anion resistance protein (TelA)
ORP33_01685	COG0477	Major facilitator Superfamily
ORP33_01690	COG2814	Major facilitator Superfamily
ORP33_01695	COG0640	Transcriptional regulator
ORP33_01700	COG0517	IMP dehydrogenase activity
ORP33_01700	COG4175	Glycine betaine
ORP33_01705	COG4176	ABC-type proline glycine betaine transport system permease component
ORP33_01710	COG2113	Glycine betaine
ORP33_01715	COG1473	amidohydrolase
ORP33_01720	COG1288	antiporter activity
ORP33_01730	COG0366	Alpha amylase catalytic
ORP33_01735	COG0039	L-malate dehydrogenase activity
ORP33_01740	COG1620	l-lactate permease
ORP33_01745	COG2814	Major facilitator Superfamily
ORP33_01750	COG1846	Transcriptional regulator
ORP33_01755	COG1280	lysine exporter protein (LysE YggA)
ORP33_01760	COG3403	YqcI/YcgG family
ORP33_01765	COG1113	amino acid transport
ORP33_01770	COG3665	Urea carboxylase-associated protein
ORP33_01775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ORP33_01780	COG1660	Displays ATPase and GTPase activities
ORP33_01785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ORP33_01790	COG2226	methyltransferase
ORP33_01795	COG0583	DNA-binding transcription factor activity
ORP33_01800	COG3458	cephalosporin-C deacetylase activity
ORP33_01805	COG3541	Predicted nucleotidyltransferase
ORP33_01810	COG0506	proline dehydrogenase activity
ORP33_01815	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_01820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ORP33_01825	COG2508	Transcriptional regulator
ORP33_01830	COG3689	TIGRFAM TIGR03943 family protein
ORP33_01835	COG0701	Predicted permease
ORP33_01840	COG2267	carboxylic ester hydrolase activity
ORP33_01845	COG0492	ferredoxin-NADP+ reductase activity
ORP33_01850	COG1587	Uroporphyrinogen-III synthase
ORP33_01850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ORP33_01855	COG2146	nitrite reductase [NAD(P)H] activity
ORP33_01860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ORP33_01865	COG0243	molybdopterin cofactor binding
ORP33_01870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ORP33_01875	COG2223	nitrite transmembrane transporter activity
ORP33_01880	COG1469	GTP cyclohydrolase I activity
ORP33_01885	COG1376	ErfK ybiS ycfS ynhG family protein
ORP33_01895	COG0523	cobalamin synthesis protein
ORP33_01900	COG0765	amino acid transport
ORP33_01905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ORP33_01910	COG1714	RDD family
ORP33_01920	COG1846	Transcriptional regulator
ORP33_01930	COG3842	ATPase activity
ORP33_01935	COG2723	6-phospho-beta-galactosidase activity
ORP33_01945	COG3209	COG3209 Rhs family protein
ORP33_01950	COG0840	transmembrane signaling receptor activity
ORP33_01950	COG3290	protein histidine kinase activity
ORP33_01955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ORP33_01960	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ORP33_01965	COG1733	regulation of RNA biosynthetic process
ORP33_01970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_02000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ORP33_02005	COG2814	Major facilitator Superfamily
ORP33_02010	COG0697	spore germination
ORP33_02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ORP33_02025	COG2364	Membrane
ORP33_02030	COG1126	abc transporter atp-binding protein
ORP33_02035	COG0765	amino acid transport
ORP33_02040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ORP33_02045	COG0583	DNA-binding transcription factor activity
ORP33_02050	COG0163	prenyltransferase activity
ORP33_02055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ORP33_02070	COG0596	Alpha beta hydrolase
ORP33_02075	COG3104	oligopeptide transport
ORP33_02080	COG5434	Belongs to the glycosyl hydrolase 28 family
ORP33_02090	COG0697	spore germination
ORP33_02100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ORP33_02105	COG1136	(ABC) transporter
ORP33_02110	COG0577	efflux transmembrane transporter activity
ORP33_02115	COG0745	RESPONSE REGULATOR receiver
ORP33_02120	COG3850	Histidine kinase
ORP33_02120	COG5002	protein histidine kinase activity
ORP33_02125	COG0457	Tetratricopeptide repeat
ORP33_02145	COG0527	aspartate kinase activity
ORP33_02150	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ORP33_02155	COG4605	iron ion homeostasis
ORP33_02160	COG4604	ABC transporter, ATP-binding protein
ORP33_02165	COG4607	ABC-type enterochelin transport system periplasmic component
ORP33_02170	COG2814	Major facilitator Superfamily
ORP33_02175	COG1309	transcriptional regulator
ORP33_02180	COG0778	Nitroreductase
ORP33_02185	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ORP33_02190	COG0640	Transcriptional regulator
ORP33_02195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ORP33_02200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ORP33_02205	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_02210	COG4975	Glucose uptake
ORP33_02215	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_02220	COG4549	nuclear export factor GLE1
ORP33_02225	COG1276	copper resistance
ORP33_02225	COG2372	response to copper ion
ORP33_02230	COG1349	DNA-binding transcription factor activity
ORP33_02240	COG2213	PTS system mannitol-specific
ORP33_02245	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ORP33_02250	COG0246	Mannitol dehydrogenase
ORP33_02255	COG0473	3-isopropylmalate dehydrogenase activity
ORP33_02260	COG0681	Belongs to the peptidase S26 family
ORP33_02265	COG0412	Dienelactone hydrolase
ORP33_02270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ORP33_02280	COG0561	phosphatase activity
ORP33_02285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ORP33_02290	COG1914	H( )-stimulated, divalent metal cation uptake system
ORP33_02295	COG4336	lyase activity
ORP33_02300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ORP33_02305	COG1984	allophanate hydrolase subunit 2
ORP33_02310	COG1414	Transcriptional regulator
ORP33_02315	COG2755	lipolytic protein G-D-S-L family
ORP33_02325	COG2329	Antibiotic biosynthesis monooxygenase
ORP33_02330	COG0768	penicillin binding
ORP33_02335	COG4989	oxidoreductase activity
ORP33_02340	COG3711	transcriptional antiterminator
ORP33_02345	COG0318	PFAM AMP-dependent synthetase and ligase
ORP33_02350	COG2226	methyltransferase
ORP33_02355	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_02360	COG1917	Cupin 2, conserved barrel domain protein
ORP33_02365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ORP33_02370	COG3871	stress protein (general stress protein 26)
ORP33_02380	COG2814	Major facilitator Superfamily
ORP33_02385	COG1522	sequence-specific DNA binding
ORP33_02390	COG0551	DNA topoisomerase type I activity
ORP33_02390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ORP33_02395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ORP33_02400	COG3706	GGDEF domain
ORP33_02405	COG5298	Protein conserved in bacteria
ORP33_02410	COG1215	transferase activity, transferring glycosyl groups
ORP33_02420	COG0531	amino acid
ORP33_02425	COG0494	nUDIX hydrolase
ORP33_02430	COG0028	Belongs to the TPP enzyme family
ORP33_02440	COG1914	H( )-stimulated, divalent metal cation uptake system
ORP33_02445	COG2261	transglycosylase associated protein
ORP33_02450	COG4876	unkown
ORP33_02455	COG2217	Heavy metal translocating P-type atpase
ORP33_02460	COG3729	General stress protein
ORP33_02465	COG0662	Cupin 2, conserved barrel domain protein
ORP33_02470	COG2329	Antibiotic biosynthesis monooxygenase
ORP33_02475	COG3546	catalase activity
ORP33_02480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ORP33_02485	COG3290	protein histidine kinase activity
ORP33_02490	COG4565	transcriptional regulatory protein
ORP33_02495	COG1301	dicarboxylic acid transport
ORP33_02500	COG0628	permease
ORP33_02505	COG1131	(ABC) transporter
ORP33_02510	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ORP33_02520	COG1960	acyl-CoA dehydrogenase activity
ORP33_02530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ORP33_02535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ORP33_02540	COG1181	Belongs to the D-alanine--D-alanine ligase family
ORP33_02545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ORP33_02550	COG0513	Belongs to the DEAD box helicase family
ORP33_02555	COG3402	PFAM membrane-flanked domain
ORP33_02560	COG3428	Bacterial PH domain
ORP33_02565	COG0705	Rhomboid family
ORP33_02570	COG0736	holo-[acyl-carrier-protein] synthase activity
ORP33_02575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ORP33_02580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ORP33_02585	COG0864	Transcriptional regulator
ORP33_02590	COG2337	Toxic component of a toxin-antitoxin (TA) module
ORP33_02595	COG1366	Belongs to the anti-sigma-factor antagonist family
ORP33_02600	COG1366	Belongs to the anti-sigma-factor antagonist family
ORP33_02605	COG2172	sigma factor antagonist activity
ORP33_02610	COG2208	phosphoserine phosphatase activity
ORP33_02615	COG1366	Belongs to the anti-sigma-factor antagonist family
ORP33_02620	COG2172	sigma factor antagonist activity
ORP33_02625	COG1191	sigma factor activity
ORP33_02630	COG2208	phosphoserine phosphatase activity
ORP33_02635	COG2183	response to ionizing radiation
ORP33_02645	COG3091	SprT-like family
ORP33_02685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ORP33_02715	COG3764	Sortase (surface protein transpeptidase)
ORP33_02720	COG1476	TRANSCRIPTIONal
ORP33_02735	COG1278	Cold shock
ORP33_02740	COG1329	Transcriptional regulator
ORP33_02745	COG0697	spore germination
ORP33_02750	COG2207	Transcriptional regulator
ORP33_02750	COG1917	Cupin 2, conserved barrel domain protein
ORP33_02755	COG0697	spore germination
ORP33_02760	COG2207	Transcriptional regulator
ORP33_02760	COG3708	Transcriptional regulator
ORP33_02765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ORP33_02770	COG0477	Major facilitator Superfamily
ORP33_02780	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ORP33_02815	COG1309	transcriptional regulator
ORP33_02820	COG0697	spore germination
ORP33_02825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ORP33_02830	COG2030	dehydratase
ORP33_02835	COG3545	Serine hydrolase
ORP33_02845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ORP33_02850	COG1733	regulation of RNA biosynthetic process
ORP33_02855	COG2249	NAD(P)H dehydrogenase (quinone) activity
ORP33_02865	COG1309	transcriptional regulator
ORP33_02870	COG0640	Transcriptional regulator
ORP33_02875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ORP33_02885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ORP33_02890	COG0697	spore germination
ORP33_02895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ORP33_02900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ORP33_02905	COG0640	Transcriptional regulator
ORP33_02910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ORP33_02915	COG4585	Histidine kinase
ORP33_02920	COG2197	response regulator
ORP33_02925	COG2409	Drug exporters of the RND superfamily
ORP33_02930	COG0596	Alpha beta hydrolase
ORP33_02935	COG1811	Na channel or pump
ORP33_02940	COG0789	Transcriptional regulator
ORP33_02940	COG4978	Transcriptional regulator
ORP33_02945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ORP33_02950	COG0778	Nitroreductase
ORP33_02955	COG0346	lactoylglutathione lyase activity
ORP33_02960	COG2259	Doxx family
ORP33_02965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ORP33_02980	COG2323	membrane
ORP33_02985	COG2323	membrane
ORP33_02990	COG0071	Belongs to the small heat shock protein (HSP20) family
ORP33_03005	COG1309	transcriptional regulator
ORP33_03015	COG0456	acetyltransferase
ORP33_03020	COG0488	(ABC) transporter
ORP33_03025	COG1113	amino acid transport
ORP33_03030	COG2318	DinB family
ORP33_03035	COG1846	Transcriptional regulator
ORP33_03040	COG1033	growth of symbiont in host cell
ORP33_03040	COG2409	Drug exporters of the RND superfamily
ORP33_03045	COG0778	Nitroreductase
ORP33_03050	COG1846	Transcriptional regulator
ORP33_03055	COG2814	Major facilitator Superfamily
ORP33_03060	COG0730	response to heat
ORP33_03065	COG1802	Transcriptional regulator
ORP33_03070	COG1388	LysM domain
ORP33_03070	COG3858	chitin binding
ORP33_03075	COG1819	glycosyl
ORP33_03085	COG1785	Belongs to the alkaline phosphatase family
ORP33_03090	COG5646	InterPro IPR014922
ORP33_03100	COG0454	-acetyltransferase
ORP33_03105	COG1078	dGTPase activity
ORP33_03110	COG1388	LysM domain
ORP33_03115	COG2814	Major facilitator Superfamily
ORP33_03120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ORP33_03125	COG1447	Phosphotransferase system cellobiose-specific component IIA
ORP33_03130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ORP33_03135	COG2723	6-phospho-beta-galactosidase activity
ORP33_03140	COG2188	Transcriptional regulator
ORP33_03145	COG1940	carbohydrate kinase activity
ORP33_03150	COG1482	cell wall glycoprotein biosynthetic process
ORP33_03155	COG4124	Belongs to the glycosyl hydrolase 26 family
ORP33_03200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ORP33_03205	COG0802	atpase or kinase
ORP33_03210	COG1214	PFAM Peptidase M22, glycoprotease
ORP33_03215	COG0456	acetyltransferase
ORP33_03220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ORP33_03225	COG0488	(ABC) transporter
ORP33_03230	COG0315	cyclic pyranopterin monophosphate synthase activity
ORP33_03235	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ORP33_03240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ORP33_03245	COG0805	protein transport
ORP33_03255	COG1266	CAAX protease self-immunity
ORP33_03265	COG0459	protein refolding
ORP33_03270	COG1073	alpha beta
ORP33_03275	COG0457	Tetratricopeptide repeat
ORP33_03280	COG1063	alcohol dehydrogenase
ORP33_03285	COG2211	Major facilitator Superfamily
ORP33_03290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ORP33_03295	COG1842	Phage shock protein A
ORP33_03300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ORP33_03305	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ORP33_03310	COG4260	virion core protein, lumpy skin disease virus
ORP33_03320	COG2814	Major facilitator Superfamily
ORP33_03325	COG1063	alcohol dehydrogenase
ORP33_03330	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ORP33_03335	COG0823	Involved in the tonB-independent uptake of proteins
ORP33_03350	COG2267	carboxylic ester hydrolase activity
ORP33_03360	COG2132	Multicopper oxidase
ORP33_03365	COG1113	amino acid transport
ORP33_03370	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ORP33_03375	COG0714	Associated with various cellular activities
ORP33_03380	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ORP33_03385	COG1305	Transglutaminase-like
ORP33_03390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ORP33_03390	COG0519	Catalyzes the synthesis of GMP from XMP
ORP33_03405	COG2252	PERMEase
ORP33_03410	COG3064	Membrane
ORP33_03420	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ORP33_03430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ORP33_03435	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ORP33_03440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ORP33_03445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ORP33_03450	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ORP33_03455	COG0047	phosphoribosylformylglycinamidine synthase activity
ORP33_03460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ORP33_03465	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ORP33_03470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ORP33_03475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ORP33_03480	COG0138	bifunctional purine biosynthesis protein purh
ORP33_03485	COG0151	Belongs to the GarS family
ORP33_03490	COG1522	sequence-specific DNA binding
ORP33_03495	COG0531	amino acid
ORP33_03505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ORP33_03510	COG1470	cell adhesion involved in biofilm formation
ORP33_03515	COG4496	protein, YerC YecD
ORP33_03520	COG0069	glutamate synthase activity
ORP33_03525	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ORP33_03530	COG0210	DNA helicase
ORP33_03535	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ORP33_03540	COG4851	CamS sex pheromone cAM373 precursor
ORP33_03545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ORP33_03550	COG1285	pathogenesis
ORP33_03555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ORP33_03560	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ORP33_03565	COG0154	amidase activity
ORP33_03570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ORP33_03575	COG1309	transcriptional regulator
ORP33_03580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ORP33_03585	COG1597	lipid kinase activity
ORP33_03590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ORP33_03605	COG0732	type I restriction modification DNA specificity domain
ORP33_03610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ORP33_03640	COG5444	nuclease activity
ORP33_03650	COG3586	endonuclease activity
ORP33_03660	COG0457	Tetratricopeptide repeat
ORP33_03670	COG0217	transcriptional regulatory protein
ORP33_03680	COG1309	transcriptional regulator
ORP33_03685	COG3631	Ketosteroid isomerase-related protein
ORP33_03690	COG0702	epimerase
ORP33_03705	COG3546	catalase activity
ORP33_03710	COG0454	-acetyltransferase
ORP33_03720	COG5578	integral membrane protein
ORP33_03725	COG2972	Histidine kinase
ORP33_03730	COG4753	response regulator
ORP33_03730	COG2207	Transcriptional regulator
ORP33_03735	COG1653	transport
ORP33_03740	COG1175	transmembrane transport
ORP33_03745	COG0395	ABC-type sugar transport system, permease component
ORP33_03750	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ORP33_03755	COG2207	Transcriptional regulator
ORP33_03760	COG2755	lipolytic protein G-D-S-L family
ORP33_03770	COG5578	integral membrane protein
ORP33_03775	COG3401	FG-GAP repeat protein
ORP33_03780	COG3401	FG-GAP repeat protein
ORP33_03785	COG2755	lipolytic protein G-D-S-L family
ORP33_03790	COG1874	Beta-galactosidase
ORP33_03800	COG1653	transport
ORP33_03805	COG4209	transmembrane transport
ORP33_03810	COG0395	ABC-type sugar transport system, permease component
ORP33_03815	COG1486	melibiose metabolic process
ORP33_03820	COG2323	membrane
ORP33_03825	COG2329	Antibiotic biosynthesis monooxygenase
ORP33_03830	COG0346	lactoylglutathione lyase activity
ORP33_03845	COG5583	Uncharacterized small protein (DUF2292)
ORP33_03850	COG0670	Belongs to the BI1 family
ORP33_03855	COG0697	spore germination
ORP33_03860	COG1846	Transcriptional regulator
ORP33_03865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ORP33_03875	COG2124	cytochrome p450
ORP33_03875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ORP33_03880	COG1368	sulfuric ester hydrolase activity
ORP33_03885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ORP33_03890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ORP33_03895	COG1442	glycosyl transferase family 8
ORP33_03900	COG1216	Glycosyl transferase, family 2
ORP33_03905	COG1442	glycosyl transferase family 8
ORP33_03910	COG2223	nitrite transmembrane transporter activity
ORP33_03915	COG1011	Hydrolase
ORP33_03920	COG0531	amino acid
ORP33_03925	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_03930	COG0840	transmembrane signaling receptor activity
ORP33_03935	COG0488	(ABC) transporter
ORP33_03945	COG0789	Transcriptional regulator
ORP33_03950	COG2814	Major facilitator Superfamily
ORP33_03960	COG0488	(ABC) transporter
ORP33_03965	COG0513	Belongs to the DEAD box helicase family
ORP33_03970	COG0456	acetyltransferase
ORP33_03975	COG2130	NADP-dependent
ORP33_03980	COG1120	ATPase activity
ORP33_03985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ORP33_03990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ORP33_03995	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ORP33_04010	COG3866	Pectate lyase
ORP33_04015	COG0471	metal ion transport
ORP33_04020	COG3290	protein histidine kinase activity
ORP33_04025	COG4565	transcriptional regulatory protein
ORP33_04030	COG3181	Tripartite tricarboxylate transporter family receptor
ORP33_04040	COG2851	Citrate transporter
ORP33_04045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ORP33_04050	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ORP33_04055	COG1254	Belongs to the acylphosphatase family
ORP33_04060	COG2258	MOSC domain
ORP33_04080	COG0024	Methionine aminopeptidase
ORP33_04085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ORP33_04085	COG1263	PTS System
ORP33_04090	COG1368	sulfuric ester hydrolase activity
ORP33_04100	COG1115	amino acid carrier protein
ORP33_04105	COG0531	amino acid
ORP33_04120	COG0697	spore germination
ORP33_04125	COG1263	PTS System
ORP33_04125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ORP33_04130	COG0366	Alpha amylase catalytic
ORP33_04135	COG2188	Transcriptional regulator
ORP33_04140	COG0778	Nitroreductase
ORP33_04145	COG0737	Belongs to the 5'-nucleotidase family
ORP33_04150	COG0693	protein deglycase activity
ORP33_04155	COG2814	Major facilitator Superfamily
ORP33_04160	COG4840	Belongs to the UPF0435 family
ORP33_04165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ORP33_04170	COG4980	gas vesicle protein
ORP33_04175	COG1295	ribonuclease BN
ORP33_04180	COG0477	Major facilitator Superfamily
ORP33_04185	COG0387	Pfam Sodium calcium exchanger
ORP33_04195	COG0668	transmembrane transport
ORP33_04200	COG0535	radical SAM domain protein
ORP33_04210	COG0726	polysaccharide deacetylase
ORP33_04215	COG2084	Dehydrogenase
ORP33_04220	COG0598	Magnesium transport protein CorA
ORP33_04225	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ORP33_04230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ORP33_04240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ORP33_04245	COG4637	Psort location Cytoplasmic, score
ORP33_04255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ORP33_04260	COG0022	dehydrogenase e1 component
ORP33_04265	COG0508	dehydrogenase complex catalyzes the overall conversion of
ORP33_04270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ORP33_04275	COG3284	Transcriptional regulator
ORP33_04285	COG1742	UPF0060 membrane protein
ORP33_04305	COG4842	Belongs to the WXG100 family
ORP33_04310	COG1486	melibiose metabolic process
ORP33_04315	COG1737	Transcriptional regulator
ORP33_04320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ORP33_04320	COG1263	PTS System
ORP33_04325	COG1132	(ABC) transporter
ORP33_04330	COG1132	(ABC) transporter
ORP33_04335	COG2259	Doxx family
ORP33_04340	COG2514	catechol 2,3-dioxygenase activity
ORP33_04345	COG4585	Histidine kinase
ORP33_04350	COG2197	response regulator
ORP33_04355	COG1131	(ABC) transporter
ORP33_04360	COG0842	Transport permease protein
ORP33_04360	COG1511	domain protein
ORP33_04365	COG0842	Transport permease protein
ORP33_04370	COG1695	Transcriptional regulator
ORP33_04375	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ORP33_04380	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ORP33_04385	COG2318	DinB family
ORP33_04390	COG2814	Major facilitator Superfamily
ORP33_04395	COG1846	Transcriptional regulator
ORP33_04400	COG0392	lysyltransferase activity
ORP33_04400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ORP33_04405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ORP33_04410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ORP33_04415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ORP33_04420	COG0384	phenazine biosynthesis protein PhzF
ORP33_04425	COG0778	Nitroreductase
ORP33_04440	COG1090	epimerase
ORP33_04445	COG2137	regulation of response to DNA damage stimulus
ORP33_04455	COG2814	Major facilitator Superfamily
ORP33_04470	COG3103	Sh3 type 3 domain protein
ORP33_04475	COG5658	integral membrane protein
ORP33_04480	COG0596	Alpha beta hydrolase
ORP33_04485	COG0463	Glycosyl transferase, family 2
ORP33_04490	COG4485	Bacterial membrane protein, YfhO
ORP33_04495	COG1988	membrane-bound metal-dependent
ORP33_04500	COG1194	a g-specific adenine glycosylase
ORP33_04510	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_04525	COG3557	Belongs to the UPF0374 family
ORP33_04530	COG1132	(ABC) transporter
ORP33_04535	COG4129	membrane
ORP33_04540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ORP33_04545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ORP33_04550	COG0735	belongs to the Fur family
ORP33_04660	COG4326	sporulation control protein
ORP33_04670	COG3340	Belongs to the peptidase S51 family
ORP33_04675	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ORP33_04680	COG0277	FAD linked oxidase domain protein
ORP33_04690	COG0753	catalase activity
ORP33_04695	COG1116	anion transmembrane transporter activity
ORP33_04700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ORP33_04705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ORP33_04710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ORP33_04720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ORP33_04730	COG1476	TRANSCRIPTIONal
ORP33_04740	COG3382	B3 4 domain protein
ORP33_04745	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ORP33_04755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ORP33_04760	COG0789	Transcriptional regulator
ORP33_04765	COG1664	Polymer-forming cytoskeletal
ORP33_04770	COG1664	Polymer-forming cytoskeletal
ORP33_04775	COG2766	serine protein kinase
ORP33_04780	COG2718	Belongs to the UPF0229 family
ORP33_04785	COG1846	Transcriptional regulator
ORP33_04790	COG1566	PFAM secretion protein HlyD family protein
ORP33_04795	COG2814	Major facilitator Superfamily
ORP33_04800	COG0655	NAD(P)H dehydrogenase (quinone) activity
ORP33_04815	COG1725	Transcriptional regulator
ORP33_04820	COG1131	(ABC) transporter
ORP33_04825	COG1131	(ABC) transporter
ORP33_04830	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ORP33_04835	COG1278	Cold shock
ORP33_04840	COG1464	Belongs to the NlpA lipoprotein family
ORP33_04845	COG3706	GGDEF domain
ORP33_04850	COG1823	symporter activity
ORP33_04870	COG5577	PFAM Coat F domain
ORP33_04875	COG1525	nuclease
ORP33_04875	COG4085	toxin activity
ORP33_04875	COG0737	Belongs to the 5'-nucleotidase family
ORP33_04880	COG3764	Sortase (surface protein transpeptidase)
ORP33_04885	COG0564	pseudouridine synthase activity
ORP33_04895	COG0517	IMP dehydrogenase activity
ORP33_04900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ORP33_04905	COG3153	acetyltransferase
ORP33_04905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ORP33_04910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ORP33_04915	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ORP33_04920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ORP33_04925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ORP33_04930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ORP33_04935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ORP33_04940	COG2203	Gaf domain
ORP33_04940	COG4585	Histidine kinase
ORP33_04945	COG2197	response regulator
ORP33_04950	COG0431	NADPH-dependent FMN reductase
ORP33_04965	COG1388	LysM domain
ORP33_04965	COG0791	NLP P60 protein
ORP33_04970	COG1959	2 iron, 2 sulfur cluster binding
ORP33_04975	COG0668	transmembrane transport
ORP33_04980	COG2719	SpoVR family
ORP33_04985	COG1785	Belongs to the alkaline phosphatase family
ORP33_04990	COG0791	NLP P60 protein
ORP33_04990	COG1388	LysM domain
ORP33_04995	COG0583	DNA-binding transcription factor activity
ORP33_05000	COG0372	Belongs to the citrate synthase family
ORP33_05005	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_05010	COG0531	amino acid
ORP33_05015	COG0733	neurotransmitter:sodium symporter activity
ORP33_05020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ORP33_05025	COG0456	acetyltransferase
ORP33_05040	COG1595	DNA-templated transcription, initiation
ORP33_05045	COG0667	Aldo Keto reductase
ORP33_05050	COG0204	Acyl-transferase
ORP33_05055	COG1253	flavin adenine dinucleotide binding
ORP33_05060	COG0789	Transcriptional regulator
ORP33_05065	COG0436	Aminotransferase
ORP33_05070	COG1253	flavin adenine dinucleotide binding
ORP33_05075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ORP33_05080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ORP33_05085	COG0584	glycerophosphoryl diester phosphodiesterase
ORP33_05095	COG0668	transmembrane transport
ORP33_05100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ORP33_05105	COG0726	polysaccharide deacetylase
ORP33_05110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ORP33_05115	COG1757	Na H antiporter
ORP33_05120	COG0589	response to stress
ORP33_05125	COG1132	(ABC) transporter
ORP33_05130	COG1132	(ABC) transporter
ORP33_05135	COG0702	epimerase
ORP33_05150	COG0189	ligase activity
ORP33_05155	COG0189	ligase activity
ORP33_05160	COG4399	Belongs to the UPF0754 family
ORP33_05165	COG3679	Belongs to the UPF0342 family
ORP33_05170	COG4335	DNA alkylation repair
ORP33_05175	COG0561	phosphatase activity
ORP33_05180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ORP33_05185	COG0475	glutathione-regulated potassium exporter activity
ORP33_05190	COG0490	domain, Protein
ORP33_05200	COG1024	Enoyl-CoA hydratase
ORP33_05210	COG4152	abc transporter atp-binding protein
ORP33_05215	COG1668	transmembrane transport
ORP33_05220	COG0420	3'-5' exonuclease activity
ORP33_05225	COG4717	serine-type aminopeptidase activity
ORP33_05230	COG3481	metal-dependent phosphohydrolase, HD sub domain
ORP33_05240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ORP33_05265	COG1846	Transcriptional regulator
ORP33_05270	COG4980	gas vesicle protein
ORP33_05285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ORP33_05290	COG0537	adenosine 5'-monophosphoramidase activity
ORP33_05295	COG1131	(ABC) transporter
ORP33_05300	COG4473	ABC transporter
ORP33_05310	COG1473	amidohydrolase
ORP33_05315	COG3069	C4-dicarboxylate transmembrane transporter activity
ORP33_05325	COG2329	Antibiotic biosynthesis monooxygenase
ORP33_05330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ORP33_05335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ORP33_05340	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ORP33_05345	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ORP33_05350	COG1309	transcriptional regulator
ORP33_05355	COG1511	domain protein
ORP33_05360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ORP33_05365	COG4377	Putative membrane peptidase family (DUF2324)
ORP33_05375	COG1363	Peptidase, m42
ORP33_05380	COG4405	Protein conserved in bacteria
ORP33_05385	COG1301	dicarboxylic acid transport
ORP33_05395	COG1234	tRNA 3'-trailer cleavage
ORP33_05400	COG0095	Lipoate-protein ligase
ORP33_05405	COG0702	epimerase
ORP33_05410	COG0318	PFAM AMP-dependent synthetase and ligase
ORP33_05420	COG0501	Belongs to the peptidase M48B family
ORP33_05430	COG0456	acetyltransferase
ORP33_05435	COG0604	alcohol dehydrogenase
ORP33_05440	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ORP33_05445	COG0406	alpha-ribazole phosphatase activity
ORP33_05450	COG0183	Belongs to the thiolase family
ORP33_05455	COG0318	PFAM AMP-dependent synthetase and ligase
ORP33_05460	COG1268	BioY protein
ORP33_05465	COG0840	transmembrane signaling receptor activity
ORP33_05470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ORP33_05470	COG0723	plastoquinol--plastocyanin reductase activity
ORP33_05475	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_05485	COG4903	ComK protein
ORP33_05490	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_05500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ORP33_05515	COG0398	Pfam SNARE associated Golgi protein
ORP33_05520	COG0681	Belongs to the peptidase S26 family
ORP33_05525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ORP33_05530	COG1846	Transcriptional regulator
ORP33_05535	COG0738	Major facilitator superfamily
ORP33_05540	COG0673	inositol 2-dehydrogenase activity
ORP33_05545	COG0561	phosphatase activity
ORP33_05550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ORP33_05555	COG1609	Transcriptional regulator
ORP33_05560	COG3180	Ammonia monooxygenase
ORP33_05565	COG2814	Major facilitator Superfamily
ORP33_05565	COG0477	Major facilitator Superfamily
ORP33_05570	COG4533	DNA binding
ORP33_05580	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ORP33_05585	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ORP33_05590	COG1074	ATP-dependent DNA helicase activity
ORP33_05595	COG0420	3'-5' exonuclease activity
ORP33_05600	COG0419	ATPase involved in DNA repair
ORP33_05605	COG1403	HNH endonuclease
ORP33_05645	COG5337	Spore coat protein CotH
ORP33_05650	COG0179	Fumarylacetoacetate (FAA) hydrolase
ORP33_05660	COG1404	Belongs to the peptidase S8 family
ORP33_05670	COG0367	asparagine synthase
ORP33_05675	COG2318	DinB family
ORP33_05680	COG1562	ergosterol biosynthetic process
ORP33_05685	COG0534	Mate efflux family protein
ORP33_05690	COG1917	Cupin 2, conserved barrel domain protein
ORP33_05690	COG2207	Transcriptional regulator
ORP33_05695	COG1609	Transcriptional regulator
ORP33_05700	COG0673	inositol 2-dehydrogenase activity
ORP33_05705	COG2318	DinB family
ORP33_05710	COG1279	arginine transmembrane transporter activity
ORP33_05715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ORP33_05720	COG1357	PFAM Pentapeptide repeats (8 copies)
ORP33_05725	COG2267	carboxylic ester hydrolase activity
ORP33_05730	COG0529	Catalyzes the synthesis of activated sulfate
ORP33_05735	COG2046	Belongs to the sulfate adenylyltransferase family
ORP33_05740	COG0175	sulfate reduction
ORP33_05745	COG2045	Belongs to the ComB family
ORP33_05750	COG1809	phosphosulfolactate synthase activity
ORP33_05755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ORP33_05760	COG4948	Mandelate Racemase Muconate Lactonizing
ORP33_05765	COG2814	Major facilitator Superfamily
ORP33_05770	COG0454	-acetyltransferase
ORP33_05775	COG2153	protein acetylation
ORP33_05780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ORP33_05780	COG0646	methionine synthase
ORP33_05785	COG1666	GTP binding
ORP33_05790	COG2996	Protein conserved in bacteria
ORP33_05810	COG1695	Transcriptional regulator
ORP33_05825	COG3227	Zinc metalloprotease (Elastase)
ORP33_05830	COG1307	EDD domain protein, DegV family
ORP33_05835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ORP33_05855	COG0561	phosphatase activity
ORP33_05860	COG1073	alpha beta
ORP33_05865	COG2151	metal-sulfur cluster biosynthetic enzyme
ORP33_05875	COG0277	FAD linked oxidase domain protein
ORP33_05880	COG2271	Major facilitator Superfamily
ORP33_05885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ORP33_05890	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ORP33_05900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ORP33_05905	COG0505	Belongs to the CarA family
ORP33_05910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ORP33_05915	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ORP33_05930	COG2267	carboxylic ester hydrolase activity
ORP33_05940	COG1744	ABC transporter substrate-binding protein PnrA-like
ORP33_05955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ORP33_05960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ORP33_05965	COG5504	Zn-dependent protease
ORP33_05970	COG0444	Belongs to the ABC transporter superfamily
ORP33_05975	COG4608	Belongs to the ABC transporter superfamily
ORP33_05985	COG0601	transmembrane transport
ORP33_05990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ORP33_06000	COG0180	Tryptophanyl-tRNA synthetase
ORP33_06005	COG4166	transmembrane transport
ORP33_06010	COG0601	transmembrane transport
ORP33_06015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ORP33_06020	COG0444	Belongs to the ABC transporter superfamily
ORP33_06025	COG4608	Belongs to the ABC transporter superfamily
ORP33_06030	COG2814	Major facilitator Superfamily
ORP33_06035	COG0456	acetyltransferase
ORP33_06040	COG1393	Belongs to the ArsC family
ORP33_06045	COG0861	Integral membrane protein TerC family
ORP33_06050	COG4862	establishment of competence for transformation
ORP33_06055	COG4469	Competence protein
ORP33_06060	COG1164	Oligoendopeptidase f
ORP33_06070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ORP33_06075	COG2346	COG2346, Truncated hemoglobins
ORP33_06080	COG0741	lytic transglycosylase activity
ORP33_06085	COG4116	CYTH
ORP33_06095	COG2357	RelA SpoT domain protein
ORP33_06100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ORP33_06105	COG0564	pseudouridine synthase activity
ORP33_06110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ORP33_06115	COG0569	domain protein
ORP33_06115	COG0475	glutathione-regulated potassium exporter activity
ORP33_06120	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ORP33_06125	COG0352	thiamine-phosphate diphosphorylase activity
ORP33_06130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ORP33_06135	COG2104	thiamine diphosphate biosynthetic process
ORP33_06140	COG2022	thiamine diphosphate biosynthetic process
ORP33_06145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ORP33_06150	COG0351	phosphomethylpyrimidine kinase
ORP33_06155	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ORP33_06210	COG0210	DNA helicase
ORP33_06220	COG2153	protein acetylation
ORP33_06225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ORP33_06230	COG2382	esterase
ORP33_06235	COG0626	cystathionine gamma-synthase activity
ORP33_06240	COG0626	cystathionine gamma-synthase activity
ORP33_06245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ORP33_06250	COG5505	Protein of unknown function (DUF819)
ORP33_06345	COG5484	DNA packaging
ORP33_06350	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ORP33_06355	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_06365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ORP33_06365	COG3711	transcriptional antiterminator
ORP33_06370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ORP33_06370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ORP33_06370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ORP33_06375	COG1482	cell wall glycoprotein biosynthetic process
ORP33_06385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ORP33_06395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ORP33_06410	COG0109	protoheme IX farnesyltransferase activity
ORP33_06420	COG0726	polysaccharide deacetylase
ORP33_06435	COG5504	Zn-dependent protease
ORP33_06440	COG2205	protein histidine kinase activity
ORP33_06450	COG3383	formate dehydrogenase (NAD+) activity
ORP33_06455	COG2427	Protein of unknown function (DUF1641)
ORP33_06465	COG1051	belongs to the nudix hydrolase family
ORP33_06475	COG2124	cytochrome p450
ORP33_06480	COG1819	glycosyl
ORP33_06490	COG1587	Uroporphyrinogen-III synthase
ORP33_06495	COG0390	transport system, permease component
ORP33_06500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ORP33_06505	COG0697	spore germination
ORP33_06510	COG4297	protein containing double-stranded beta helix domain
ORP33_06520	COG1252	NADH dehydrogenase
ORP33_06525	COG1904	glucuronate isomerase
ORP33_06530	COG2211	Major facilitator Superfamily
ORP33_06535	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ORP33_06540	COG1063	alcohol dehydrogenase
ORP33_06545	COG1312	Catalyzes the dehydration of D-mannonate
ORP33_06550	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_06555	COG2271	Major facilitator Superfamily
ORP33_06560	COG1609	Transcriptional regulator
ORP33_06565	COG0246	Mannitol dehydrogenase
ORP33_06570	COG2721	sulfolactate sulfo-lyase activity
ORP33_06575	COG0730	response to heat
ORP33_06580	COG2318	DinB family
ORP33_06585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ORP33_06590	COG0457	Tetratricopeptide repeat
ORP33_06600	COG2350	Protein conserved in bacteria
ORP33_06605	COG1388	LysM domain
ORP33_06605	COG3409	Peptidoglycan-binding domain 1 protein
ORP33_06605	COG5632	N-Acetylmuramoyl-L-alanine amidase
ORP33_06615	COG4195	phage-related replication protein
ORP33_06620	COG3546	catalase activity
ORP33_06625	COG2856	Zn peptidase
ORP33_06630	COG1396	sequence-specific DNA binding
ORP33_06640	COG1522	sequence-specific DNA binding
ORP33_06645	COG1484	DNA-dependent DNA replication
ORP33_06665	COG1595	DNA-templated transcription, initiation
ORP33_06670	COG5484	DNA packaging
ORP33_06670	COG3728	DNA packaging
ORP33_06675	COG1783	phage Terminase large subunit
ORP33_06680	COG5518	Phage portal protein
ORP33_06685	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ORP33_06690	COG4653	Phage capsid family
ORP33_06735	COG5412	phage tail tape measure protein
ORP33_06735	COG3953	SLT domain
ORP33_06740	COG1652	LysM domain
ORP33_06745	COG4193	domain, Protein
ORP33_06755	COG3628	GPW Gp25 family protein
ORP33_06760	COG3299	homolog of phage Mu protein gp47
ORP33_06765	COG3778	Protein conserved in bacteria
ORP33_06805	COG5632	N-Acetylmuramoyl-L-alanine amidase
ORP33_06805	COG3409	Peptidoglycan-binding domain 1 protein
ORP33_06825	COG0306	phosphate transporter
ORP33_06830	COG1392	Phosphate transport regulator
ORP33_06835	COG0531	amino acid
ORP33_06840	COG0346	lactoylglutathione lyase activity
ORP33_06845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ORP33_06850	COG0463	Glycosyl transferase, family 2
ORP33_06855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ORP33_06860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ORP33_06865	COG2362	D-Aminopeptidase
ORP33_06870	COG0601	transmembrane transport
ORP33_06875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ORP33_06880	COG0444	Belongs to the ABC transporter superfamily
ORP33_06885	COG4166	transmembrane transport
ORP33_06890	COG1619	proteins homologs of microcin C7 resistance protein MccF
ORP33_06895	COG4948	Mandelate Racemase Muconate Lactonizing
ORP33_06900	COG0791	NLP P60 protein
ORP33_06905	COG4608	Belongs to the ABC transporter superfamily
ORP33_06910	COG2706	6-phosphogluconolactonase activity
ORP33_06915	COG1834	amidinotransferase
ORP33_06920	COG1607	acyl-coa hydrolase
ORP33_06925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ORP33_06925	COG1017	nitric oxide dioxygenase activity
ORP33_06930	COG2323	membrane
ORP33_06935	COG2318	DinB family
ORP33_06940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ORP33_06945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ORP33_06950	COG2076	Multidrug Resistance protein
ORP33_06955	COG2076	Multidrug Resistance protein
ORP33_06960	COG0788	formyltetrahydrofolate deformylase activity
ORP33_06965	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ORP33_06970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ORP33_06975	COG1764	response to oxidative stress
ORP33_06980	COG1846	Transcriptional regulator
ORP33_06985	COG1764	response to oxidative stress
ORP33_06995	COG0590	tRNA wobble adenosine to inosine editing
ORP33_07005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ORP33_07010	COG1404	Belongs to the peptidase S8 family
ORP33_07015	COG1366	Belongs to the anti-sigma-factor antagonist family
ORP33_07020	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ORP33_07025	COG1122	ATPase activity
ORP33_07030	COG4721	ABC-type cobalt transport system, permease component
ORP33_07040	COG0745	RESPONSE REGULATOR receiver
ORP33_07045	COG3850	Histidine kinase
ORP33_07045	COG5002	protein histidine kinase activity
ORP33_07050	COG3212	peptidase
ORP33_07055	COG3212	peptidase
ORP33_07070	COG2239	Acts as a magnesium transporter
ORP33_07075	COG0789	Transcriptional regulator
ORP33_07090	COG1846	Transcriptional regulator
ORP33_07095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ORP33_07100	COG0726	polysaccharide deacetylase
ORP33_07105	COG1408	metallophosphoesterase
ORP33_07115	COG0463	Glycosyl transferase, family 2
ORP33_07120	COG1793	dna ligase
ORP33_07120	COG3285	dna ligase
ORP33_07125	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ORP33_07130	COG5001	Diguanylate cyclase
ORP33_07130	COG3300	MHYT domain
ORP33_07135	COG0586	Pfam SNARE associated Golgi protein
ORP33_07140	COG0861	Integral membrane protein TerC family
ORP33_07145	COG1191	sigma factor activity
ORP33_07165	COG0501	Belongs to the peptidase M48B family
ORP33_07170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ORP33_07185	COG3594	Acyltransferase
ORP33_07190	COG5002	protein histidine kinase activity
ORP33_07195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ORP33_07205	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ORP33_07210	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ORP33_07215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ORP33_07220	COG0436	Aminotransferase
ORP33_07225	COG1850	ribulose-bisphosphate carboxylase activity
ORP33_07230	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ORP33_07235	COG0235	Class ii aldolase
ORP33_07240	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ORP33_07245	COG3339	Conserved Protein
ORP33_07260	COG3852	Histidine kinase
ORP33_07265	COG1846	Transcriptional regulator
ORP33_07270	COG1360	Flagellar Motor Protein
ORP33_07275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ORP33_07280	COG0542	response to heat
ORP33_07285	COG3949	Membrane
ORP33_07290	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ORP33_07295	COG0720	synthase
ORP33_07300	COG0602	queuosine metabolic process
ORP33_07305	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ORP33_07310	COG1733	regulation of RNA biosynthetic process
ORP33_07315	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_07320	COG1388	LysM domain
ORP33_07320	COG4641	Protein conserved in bacteria
ORP33_07325	COG1388	LysM domain
ORP33_07330	COG3858	chitin binding
ORP33_07340	COG4873	Protein conserved in bacteria
ORP33_07350	COG3773	Cell wall hydrolase
ORP33_07355	COG2244	polysaccharide biosynthetic process
ORP33_07360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ORP33_07365	COG2217	Heavy metal translocating P-type atpase
ORP33_07370	COG0006	proline dipeptidase activity
ORP33_07375	COG1609	Transcriptional regulator
ORP33_07380	COG3711	transcriptional antiterminator
ORP33_07385	COG2190	(PTS) system
ORP33_07385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ORP33_07385	COG1263	PTS System
ORP33_07390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ORP33_07395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ORP33_07405	COG1533	DNA photolyase activity
ORP33_07410	COG0456	acetyltransferase
ORP33_07415	COG0840	transmembrane signaling receptor activity
ORP33_07420	COG2084	Dehydrogenase
ORP33_07425	COG2340	Cysteine-rich secretory protein family
ORP33_07430	COG0768	penicillin binding
ORP33_07435	COG4191	Histidine kinase
ORP33_07440	COG0436	Aminotransferase
ORP33_07450	COG0784	Response regulator, receiver
ORP33_07450	COG0835	chemotaxis
ORP33_07460	COG2814	Major facilitator Superfamily
ORP33_07465	COG1376	ErfK ybiS ycfS ynhG family protein
ORP33_07470	COG1408	metallophosphoesterase
ORP33_07475	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_07480	COG2200	EAL domain
ORP33_07485	COG4703	Protein of unknown function (DUF1797)
ORP33_07490	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ORP33_07500	COG0517	IMP dehydrogenase activity
ORP33_07505	COG0583	DNA-binding transcription factor activity
ORP33_07510	COG0716	FMN binding
ORP33_07520	COG0716	FMN binding
ORP33_07525	COG2171	N-acyltransferase activity
ORP33_07530	COG1473	amidohydrolase
ORP33_07540	COG0668	transmembrane transport
ORP33_07545	COG0450	alkyl hydroperoxide reductase
ORP33_07550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ORP33_07565	COG0746	molybdenum cofactor guanylyltransferase activity
ORP33_07570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ORP33_07575	COG0303	'Molybdopterin
ORP33_07580	COG1763	Mo-molybdopterin cofactor biosynthetic process
ORP33_07585	COG0314	molybdopterin synthase activity
ORP33_07590	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ORP33_07595	COG1132	(ABC) transporter
ORP33_07600	COG1132	(ABC) transporter
ORP33_07610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ORP33_07615	COG1136	(ABC) transporter
ORP33_07620	COG0577	efflux transmembrane transporter activity
ORP33_07625	COG1349	DNA-binding transcription factor activity
ORP33_07630	COG1105	Belongs to the carbohydrate kinase PfkB family
ORP33_07635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ORP33_07635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ORP33_07635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ORP33_07640	COG0681	Belongs to the peptidase S26 family
ORP33_07650	COG0488	(ABC) transporter
ORP33_07655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ORP33_07660	COG2309	aminopeptidase activity
ORP33_07670	COG1077	Cell shape determining protein MreB Mrl
ORP33_07675	COG2002	toxin-antitoxin pair type II binding
ORP33_07680	COG3852	Histidine kinase
ORP33_07685	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ORP33_07685	COG2105	PFAM AIG2 family protein
ORP33_07690	COG0569	domain protein
ORP33_07695	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ORP33_07700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ORP33_07705	COG5503	Protein of unknown function (DUF1447)
ORP33_07710	COG0561	phosphatase activity
ORP33_07715	COG0242	peptide deformylase activity
ORP33_07725	COG0497	DNA recombination
ORP33_07730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ORP33_07735	COG0022	dehydrogenase e1 component
ORP33_07740	COG0508	dehydrogenase complex catalyzes the overall conversion of
ORP33_07745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ORP33_07750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ORP33_07760	COG1982	Orn Lys Arg decarboxylase major
ORP33_07765	COG4476	Belongs to the UPF0223 family
ORP33_07770	COG4493	Belongs to the UPF0637 family
ORP33_07780	COG0483	inositol monophosphate 1-phosphatase activity
ORP33_07790	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ORP33_07810	COG1595	DNA-templated transcription, initiation
ORP33_07830	COG1217	gtp-binding protein TYPA
ORP33_07840	COG4896	Protein conserved in bacteria
ORP33_07850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ORP33_07855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ORP33_07860	COG2066	Belongs to the glutaminase family
ORP33_07865	COG4838	Belongs to the UPF0358 family
ORP33_07870	COG0772	Belongs to the SEDS family
ORP33_07875	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ORP33_07880	COG1612	heme a metabolic process
ORP33_07885	COG0109	protoheme IX farnesyltransferase activity
ORP33_07890	COG2010	Cytochrome c
ORP33_07890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ORP33_07895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ORP33_07900	COG1845	cytochrome c oxidase, subunit III
ORP33_07905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ORP33_07910	COG3336	cytochrome c oxidase
ORP33_07920	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ORP33_07925	COG2340	Cysteine-rich secretory protein family
ORP33_07940	COG3679	Belongs to the UPF0342 family
ORP33_07945	COG4471	UPF0298 protein
ORP33_07950	COG0742	ribosomal rna small subunit methyltransferase
ORP33_07955	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ORP33_07960	COG3314	Sporulation integral membrane protein YlbJ
ORP33_07965	COG1752	Esterase of the alpha-beta hydrolase superfamily
ORP33_07970	COG3480	Lon protease (S16) C-terminal proteolytic domain
ORP33_07975	COG1323	Belongs to the UPF0348 family
ORP33_07980	COG1399	metal-binding, possibly nucleic acid-binding protein
ORP33_07995	COG0454	-acetyltransferase
ORP33_08000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ORP33_08005	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ORP33_08010	COG2001	Belongs to the MraZ family
ORP33_08015	COG0275	rRNA processing
ORP33_08020	COG4839	cell division protein FtsL
ORP33_08025	COG0768	penicillin binding
ORP33_08030	COG0768	penicillin binding
ORP33_08035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ORP33_08040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ORP33_08045	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ORP33_08050	COG0772	Belongs to the SEDS family
ORP33_08055	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ORP33_08060	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ORP33_08065	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ORP33_08070	COG3879	Bacterial protein of unknown function (DUF881)
ORP33_08075	COG3879	Bacterial protein of unknown function (DUF881)
ORP33_08080	COG3856	small basic protein
ORP33_08085	COG0849	cell division
ORP33_08090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ORP33_08095	COG1404	Belongs to the peptidase S8 family
ORP33_08095	COG4412	M6 family metalloprotease domain protein
ORP33_08105	COG1191	sigma factor activity
ORP33_08110	COG1191	sigma factor activity
ORP33_08115	COG1119	ATPase activity
ORP33_08120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ORP33_08125	COG1873	PFAM PRC-barrel domain
ORP33_08130	COG1496	oxidoreductase activity
ORP33_08135	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ORP33_08140	COG1799	cell septum assembly
ORP33_08145	COG0762	integral membrane protein
ORP33_08150	COG2302	S4 RNA-binding domain
ORP33_08155	COG3599	regulation of cell shape
ORP33_08160	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ORP33_08165	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ORP33_08170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ORP33_08175	COG0564	pseudouridine synthase activity
ORP33_08180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ORP33_08185	COG2233	PERMEase
ORP33_08190	COG0540	Belongs to the ATCase OTCase family
ORP33_08195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ORP33_08200	COG0505	Belongs to the CarA family
ORP33_08205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ORP33_08210	COG0543	2 iron, 2 sulfur cluster binding
ORP33_08215	COG0167	dihydroorotate dehydrogenase activity
ORP33_08220	COG0284	orotidine-5'-phosphate decarboxylase activity
ORP33_08225	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ORP33_08230	COG0175	sulfate reduction
ORP33_08235	COG0306	phosphate transporter
ORP33_08240	COG2046	Belongs to the sulfate adenylyltransferase family
ORP33_08245	COG0529	Catalyzes the synthesis of activated sulfate
ORP33_08250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ORP33_08255	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
ORP33_08260	COG1648	precorrin-2 dehydrogenase activity
ORP33_08265	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ORP33_08270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ORP33_08275	COG1561	YicC-like family, N-terminal region
ORP33_08285	COG0194	GDP metabolic process
ORP33_08290	COG1758	RNA polymerase activity
ORP33_08295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ORP33_08300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ORP33_08305	COG0242	peptide deformylase activity
ORP33_08310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ORP33_08315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ORP33_08315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ORP33_08320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ORP33_08325	COG0631	protein serine/threonine phosphatase activity
ORP33_08330	COG0515	serine threonine protein kinase
ORP33_08330	COG2815	serine threonine protein kinase
ORP33_08335	COG1162	GTPase activity
ORP33_08340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ORP33_08345	COG1564	THIamine pyrophosphokinase
ORP33_08355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ORP33_08360	COG1302	Protein conserved in bacteria
ORP33_08365	COG1461	Dihydroxyacetone kinase
ORP33_08370	COG1760	l-serine dehydratase
ORP33_08375	COG1760	l-serine dehydratase
ORP33_08380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ORP33_08385	COG1349	DNA-binding transcription factor activity
ORP33_08385	COG2050	protein possibly involved in aromatic compounds catabolism
ORP33_08390	COG0416	fatty acid biosynthetic process
ORP33_08395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ORP33_08400	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_08410	COG0571	ribonuclease III activity
ORP33_08415	COG1196	nuclear chromosome segregation
ORP33_08420	COG0552	protein localization to endoplasmic reticulum
ORP33_08430	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ORP33_08435	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ORP33_08440	COG0228	four-way junction DNA binding
ORP33_08445	COG1837	Belongs to the UPF0109 family
ORP33_08455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ORP33_08460	COG0336	Belongs to the RNA methyltransferase TrmD family
ORP33_08465	COG0335	large ribosomal subunit rRNA binding
ORP33_08470	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ORP33_08475	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ORP33_08485	COG2257	FlhB HrpN YscU SpaS Family
ORP33_08490	COG0045	succinate-CoA ligase (ADP-forming) activity
ORP33_08495	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ORP33_08500	COG0758	DNA mediated transformation
ORP33_08505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ORP33_08510	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ORP33_08515	COG4974	Belongs to the 'phage' integrase family
ORP33_08520	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ORP33_08525	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ORP33_08530	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ORP33_08535	COG1815	bacterial-type flagellum-dependent cell motility
ORP33_08540	COG1558	bacterial-type flagellum-dependent cell motility
ORP33_08545	COG1677	Flagellar hook-basal body complex protein FliE
ORP33_08550	COG1766	The M ring may be actively involved in energy transduction
ORP33_08555	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ORP33_08560	COG1317	bacterial-type flagellum organization
ORP33_08565	COG1157	protein secretion by the type III secretion system
ORP33_08570	COG2882	bacterial-type flagellum organization
ORP33_08575	COG3334	PFAM MgtE intracellular
ORP33_08580	COG3144	bacterial-type flagellum assembly
ORP33_08585	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ORP33_08590	COG4786	Flagellar basal body rod
ORP33_08595	COG1582	Flagellar protein (FlbD)
ORP33_08600	COG1580	Controls the rotational direction of flagella during chemotaxis
ORP33_08605	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ORP33_08610	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ORP33_08610	COG1776	CheC inhibitor of MCP methylation
ORP33_08615	COG2201	protein-glutamate methylesterase activity
ORP33_08620	COG3190	flagellar
ORP33_08625	COG1338	Plays a role in the flagellum-specific transport system
ORP33_08630	COG1987	bacterial-type flagellum assembly
ORP33_08635	COG1684	flagellar biosynthetic protein fliR
ORP33_08640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ORP33_08645	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ORP33_08650	COG1419	protein localization to endoplasmic reticulum
ORP33_08655	COG0455	bacterial-type flagellum organization
ORP33_08660	COG2201	protein-glutamate methylesterase activity
ORP33_08665	COG2198	Histidine kinase
ORP33_08665	COG0643	Histidine kinase
ORP33_08670	COG0835	chemotaxis
ORP33_08675	COG1776	CheC inhibitor of MCP methylation
ORP33_08680	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ORP33_08685	COG1191	sigma factor activity
ORP33_08695	COG0052	Belongs to the universal ribosomal protein uS2 family
ORP33_08700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ORP33_08705	COG0528	UMP kinase activity
ORP33_08710	COG0233	cytoplasmic translational termination
ORP33_08715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ORP33_08720	COG4589	Belongs to the CDS family
ORP33_08725	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ORP33_08730	COG0750	zinc metalloprotease
ORP33_08735	COG0442	prolyl-tRNA aminoacylation
ORP33_08740	COG2176	DNA-directed DNA polymerase activity
ORP33_08745	COG0779	Required for maturation of 30S ribosomal subunits
ORP33_08750	COG0195	Participates in both transcription termination and antitermination
ORP33_08755	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ORP33_08760	COG1358	cellular component organization or biogenesis
ORP33_08765	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ORP33_08770	COG1550	Protein conserved in bacteria
ORP33_08775	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ORP33_08780	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ORP33_08785	COG0196	riboflavin kinase activity
ORP33_08790	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ORP33_08795	COG1185	polyribonucleotide nucleotidyltransferase activity
ORP33_08800	COG0726	polysaccharide deacetylase
ORP33_08805	COG0612	Peptidase, M16
ORP33_08810	COG1873	PFAM PRC-barrel domain
ORP33_08815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ORP33_08820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ORP33_08825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ORP33_08830	COG0527	aspartate kinase activity
ORP33_08835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ORP33_08840	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ORP33_08845	COG0740	serine-type endopeptidase activity
ORP33_08855	COG4980	gas vesicle protein
ORP33_08855	COG1674	ftsk spoiiie
ORP33_08860	COG2188	Transcriptional regulator
ORP33_08865	COG2814	Major facilitator Superfamily
ORP33_08870	COG0612	Peptidase, M16
ORP33_08875	COG0612	Peptidase, M16
ORP33_08880	COG0300	oxidoreductase activity
ORP33_08895	COG1426	Protein conserved in bacteria
ORP33_08900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ORP33_08905	COG1546	Belongs to the CinA family
ORP33_08905	COG1058	Belongs to the CinA family
ORP33_08910	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ORP33_08915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ORP33_08920	COG1418	mRNA catabolic process
ORP33_08925	COG1692	metallophosphoesterase
ORP33_08930	COG2359	stage V sporulation protein S
ORP33_08935	COG1063	alcohol dehydrogenase
ORP33_08940	COG0156	8-amino-7-oxononanoate synthase activity
ORP33_08945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ORP33_08950	COG4550	Control of competence regulator ComK, YlbF/YmcA
ORP33_08960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ORP33_08965	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ORP33_08980	COG3226	Transcriptional regulator
ORP33_08985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ORP33_08990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ORP33_08995	COG3321	synthase
ORP33_09000	COG2070	2-Nitropropane dioxygenase
ORP33_09000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ORP33_09005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ORP33_09010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ORP33_09015	COG3425	synthase
ORP33_09020	COG1024	Enoyl-CoA hydratase
ORP33_09025	COG1024	Enoyl-CoA hydratase
ORP33_09030	COG3321	synthase
ORP33_09030	COG0300	oxidoreductase activity
ORP33_09030	COG0318	PFAM AMP-dependent synthetase and ligase
ORP33_09030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_09030	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_09035	COG4221	oxidoreductase activity
ORP33_09035	COG3321	synthase
ORP33_09035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ORP33_09035	COG0300	oxidoreductase activity
ORP33_09040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_09040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ORP33_09040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ORP33_09040	COG3321	synthase
ORP33_09040	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_09045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_09045	COG4221	oxidoreductase activity
ORP33_09045	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_09045	COG3321	synthase
ORP33_09050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ORP33_09050	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ORP33_09050	COG3321	synthase
ORP33_09050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ORP33_09055	COG2124	cytochrome p450
ORP33_09065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ORP33_09070	COG1404	Belongs to the peptidase S8 family
ORP33_09080	COG4195	phage-related replication protein
ORP33_09085	COG1764	response to oxidative stress
ORP33_09090	COG2076	Multidrug Resistance protein
ORP33_09095	COG2076	Multidrug Resistance protein
ORP33_09110	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ORP33_09115	COG1923	regulation of RNA biosynthetic process
ORP33_09130	COG1780	Probably involved in ribonucleotide reductase function
ORP33_09135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ORP33_09140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ORP33_09145	COG4112	unkown
ORP33_09150	COG0860	N-Acetylmuramoyl-L-alanine amidase
ORP33_09155	COG0464	growth
ORP33_09160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ORP33_09165	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ORP33_09170	COG0789	Transcriptional regulator
ORP33_09175	COG0174	glutamine synthetase
ORP33_09210	COG0463	Glycosyl transferase, family 2
ORP33_09220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ORP33_09240	COG0135	phosphoribosylanthranilate isomerase activity
ORP33_09245	COG2211	Major facilitator Superfamily
ORP33_09250	COG3507	Belongs to the glycosyl hydrolase 43 family
ORP33_09255	COG1940	carbohydrate kinase activity
ORP33_09260	COG2115	Belongs to the xylose isomerase family
ORP33_09265	COG1070	Carbohydrate kinase
ORP33_09270	COG1525	nuclease
ORP33_09275	COG2814	Major facilitator Superfamily
ORP33_09280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ORP33_09290	COG0756	dUTP diphosphatase activity
ORP33_09300	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ORP33_09325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ORP33_09335	COG3832	glyoxalase III activity
ORP33_09350	COG0697	spore germination
ORP33_09355	COG0531	amino acid
ORP33_09385	COG4195	phage-related replication protein
ORP33_09400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ORP33_09405	COG1388	LysM domain
ORP33_09410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ORP33_09415	COG4224	UPF0291 protein
ORP33_09420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ORP33_09430	COG3763	UPF0154 protein
ORP33_09440	COG0785	Cytochrome C biogenesis protein
ORP33_09445	COG2201	protein-glutamate methylesterase activity
ORP33_09450	COG4846	Membrane protein involved in cytochrome C biogenesis
ORP33_09460	COG0071	Belongs to the small heat shock protein (HSP20) family
ORP33_09475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ORP33_09480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ORP33_09500	COG0824	Thioesterase
ORP33_09510	COG4841	protein insertion into membrane
ORP33_09515	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ORP33_09520	COG1832	CoA-binding protein
ORP33_09525	COG0187	DNA topoisomerase II activity
ORP33_09530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ORP33_09545	COG1115	amino acid carrier protein
ORP33_09550	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ORP33_09560	COG5520	Belongs to the glycosyl hydrolase 30 family
ORP33_09565	COG3507	Belongs to the glycosyl hydrolase 43 family
ORP33_09570	COG2246	polysaccharide biosynthetic process
ORP33_09575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ORP33_09580	COG0586	Pfam SNARE associated Golgi protein
ORP33_09585	COG2404	hydrolase activity, acting on ester bonds
ORP33_09590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ORP33_09595	COG1024	Enoyl-CoA hydratase
ORP33_09600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ORP33_09605	COG0511	ligase activity, forming carbon-carbon bonds
ORP33_09610	COG0439	Biotin carboxylase
ORP33_09615	COG0318	PFAM AMP-dependent synthetase and ligase
ORP33_09620	COG1960	acyl-CoA dehydrogenase activity
ORP33_09630	COG1649	PFAM Uncharacterised BCR, COG1649
ORP33_09640	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ORP33_09640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_09645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_09650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_09655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_09660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_09665	COG2027	D-alanyl-D-alanine carboxypeptidase
ORP33_09670	COG2017	converts alpha-aldose to the beta-anomer
ORP33_09675	COG0534	Mate efflux family protein
ORP33_09690	COG0582	viral genome integration into host DNA
ORP33_09695	COG0166	Belongs to the GPI family
ORP33_09700	COG0405	Gamma-glutamyltransferase
ORP33_09705	COG0583	DNA-binding transcription factor activity
ORP33_09710	COG0604	alcohol dehydrogenase
ORP33_09715	COG0493	'glutamate synthase
ORP33_09720	COG0070	glutamate synthase
ORP33_09720	COG0069	glutamate synthase activity
ORP33_09720	COG0067	glutamate synthase
ORP33_09725	COG0583	DNA-binding transcription factor activity
ORP33_09730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ORP33_09735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ORP33_09745	COG0300	oxidoreductase activity
ORP33_09750	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ORP33_09760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ORP33_09775	COG2814	Major facilitator Superfamily
ORP33_09780	COG1070	Carbohydrate kinase
ORP33_09785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ORP33_09790	COG0243	molybdopterin cofactor binding
ORP33_09815	COG5278	phosphoserine phosphatase activity
ORP33_09815	COG0840	transmembrane signaling receptor activity
ORP33_09820	COG2368	4-hydroxyphenylacetate
ORP33_09825	COG4305	rare lipoprotein A
ORP33_09830	COG3619	membrane
ORP33_09835	COG3866	Pectate lyase
ORP33_09840	COG2135	peptidase activity
ORP33_09850	COG2140	Oxalate decarboxylase
ORP33_09860	COG0456	acetyltransferase
ORP33_09875	COG2720	vancomycin resistance protein
ORP33_09885	COG3655	Transcriptional regulator
ORP33_09890	COG3739	integral membrane protein
ORP33_09895	COG0583	DNA-binding transcription factor activity
ORP33_09900	COG0697	spore germination
ORP33_09910	COG0693	protein deglycase activity
ORP33_09915	COG2367	Beta-lactamase
ORP33_09925	COG3848	Pyruvate phosphate dikinase
ORP33_09925	COG0574	Belongs to the PEP-utilizing enzyme family
ORP33_09930	COG0726	polysaccharide deacetylase
ORP33_09935	COG2314	TM2 domain
ORP33_09940	COG1396	sequence-specific DNA binding
ORP33_09970	COG1793	dna ligase
ORP33_10005	COG1388	LysM domain
ORP33_10025	COG0457	Tetratricopeptide repeat
ORP33_10035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ORP33_10055	COG5444	nuclease activity
ORP33_10060	COG4282	regulation of fungal-type cell wall biogenesis
ORP33_10065	COG1231	oxidoreductase activity
ORP33_10070	COG5434	Belongs to the glycosyl hydrolase 28 family
ORP33_10075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ORP33_10080	COG0662	Cupin 2, conserved barrel domain protein
ORP33_10080	COG2207	Transcriptional regulator
ORP33_10085	COG0456	acetyltransferase
ORP33_10090	COG1309	transcriptional regulator
ORP33_10095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ORP33_10100	COG3708	Transcriptional regulator
ORP33_10105	COG2378	regulation of single-species biofilm formation
ORP33_10115	COG0640	Transcriptional regulator
ORP33_10120	COG0741	lytic transglycosylase activity
ORP33_10125	COG2322	membrane
ORP33_10140	COG1619	proteins homologs of microcin C7 resistance protein MccF
ORP33_10145	COG3239	Fatty acid desaturase
ORP33_10150	COG4585	Histidine kinase
ORP33_10155	COG2197	response regulator
ORP33_10160	COG1388	LysM domain
ORP33_10160	COG3584	3D domain protein
ORP33_10165	COG0514	ATP-dependent DNA helicase (RecQ)
ORP33_10175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ORP33_10180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ORP33_10195	COG0071	Belongs to the small heat shock protein (HSP20) family
ORP33_10220	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_10225	COG1657	PFAM Prenyltransferase squalene oxidase
ORP33_10230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ORP33_10235	COG0733	neurotransmitter:sodium symporter activity
ORP33_10240	COG0385	Bile acid
ORP33_10245	COG0508	dehydrogenase complex catalyzes the overall conversion of
ORP33_10250	COG0567	Dehydrogenase, E1 component
ORP33_10255	COG4548	von Willebrand factor, type A
ORP33_10260	COG0714	Associated with various cellular activities
ORP33_10265	COG2032	superoxide dismutase activity
ORP33_10270	COG1388	LysM domain
ORP33_10270	COG0791	NLP P60 protein
ORP33_10275	COG1819	glycosyl
ORP33_10280	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ORP33_10285	COG0534	Mate efflux family protein
ORP33_10290	COG1366	Belongs to the anti-sigma-factor antagonist family
ORP33_10295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ORP33_10300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ORP33_10310	COG2962	Rard protein
ORP33_10330	COG1942	4-Oxalocrotonate Tautomerase
ORP33_10335	COG1733	regulation of RNA biosynthetic process
ORP33_10340	COG0778	Nitroreductase
ORP33_10345	COG0400	carboxylic ester hydrolase activity
ORP33_10350	COG0346	lactoylglutathione lyase activity
ORP33_10360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ORP33_10365	COG3409	Peptidoglycan-binding domain 1 protein
ORP33_10365	COG0793	Belongs to the peptidase S41A family
ORP33_10370	COG2226	methyltransferase
ORP33_10380	COG1876	peptidase activity
ORP33_10385	COG0813	purine-nucleoside phosphorylase activity
ORP33_10400	COG0671	phosphoesterase, PA-phosphatase related
ORP33_10420	COG4479	Belongs to the UPF0346 family
ORP33_10430	COG1509	lysine 2,3-aminomutase activity
ORP33_10435	COG0456	acetyltransferase
ORP33_10440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ORP33_10445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ORP33_10450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ORP33_10455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ORP33_10465	COG0456	acetyltransferase
ORP33_10470	COG0463	Glycosyl transferase, family 2
ORP33_10485	COG4641	Protein conserved in bacteria
ORP33_10490	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
ORP33_10495	COG1086	Polysaccharide biosynthesis protein
ORP33_10500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ORP33_10505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ORP33_10510	COG1846	Transcriptional regulator
ORP33_10515	COG0534	Mate efflux family protein
ORP33_10525	COG4698	Protein conserved in bacteria
ORP33_10530	COG2755	lipolytic protein G-D-S-L family
ORP33_10535	COG1999	signal sequence binding
ORP33_10545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ORP33_10550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ORP33_10555	COG1272	protein, Hemolysin III
ORP33_10560	COG0204	Acyl-transferase
ORP33_10565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ORP33_10570	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ORP33_10575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ORP33_10585	COG2521	methyltransferase
ORP33_10585	COG2136	Putative SAM-dependent methyltransferase
ORP33_10595	COG0129	dihydroxy-acid dehydratase activity
ORP33_10600	COG1413	lyase activity
ORP33_10605	COG1418	mRNA catabolic process
ORP33_10610	COG0386	Belongs to the glutathione peroxidase family
ORP33_10615	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ORP33_10620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ORP33_10625	COG1278	Cold shock
ORP33_10645	COG0328	RNA-DNA hybrid ribonuclease activity
ORP33_10650	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ORP33_10655	COG0328	RNA-DNA hybrid ribonuclease activity
ORP33_10665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ORP33_10680	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ORP33_10690	COG1755	Isoprenylcysteine carboxyl methyltransferase
ORP33_10695	COG3424	synthase
ORP33_10700	COG2233	PERMEase
ORP33_10705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ORP33_10710	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ORP33_10720	COG0800	Aldolase
ORP33_10725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ORP33_10730	COG1609	Transcriptional regulator
ORP33_10735	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ORP33_10740	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_10745	COG1199	ATP-dependent helicase activity
ORP33_10760	COG0116	Belongs to the methyltransferase superfamily
ORP33_10775	COG4474	Belongs to the UPF0398 family
ORP33_10785	COG3359	exonuclease
ORP33_10790	COG1205	dead DEAH box helicase
ORP33_10790	COG1111	helicase
ORP33_10795	COG2190	(PTS) system
ORP33_10800	COG0071	Belongs to the small heat shock protein (HSP20) family
ORP33_10835	COG3331	DNA recombination
ORP33_10840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ORP33_10840	COG4499	WXG100 protein secretion system (Wss), protein YukC
ORP33_10850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ORP33_10855	COG3935	DnaD domain protein
ORP33_10860	COG0017	Asparaginyl-tRNA synthetase
ORP33_10865	COG0436	Aminotransferase
ORP33_10870	COG5353	protein conserved in bacteria
ORP33_10880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ORP33_10880	COG1199	ATP-dependent helicase activity
ORP33_10885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ORP33_10890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ORP33_10895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ORP33_10900	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ORP33_10900	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ORP33_10905	COG0617	tRNA 3'-terminal CCA addition
ORP33_10910	COG0438	transferase activity, transferring glycosyl groups
ORP33_10915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ORP33_10920	COG1803	Methylglyoxal synthase
ORP33_10925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ORP33_10930	COG1694	Mazg nucleotide pyrophosphohydrolase
ORP33_10935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ORP33_10945	COG4347	Protein of unknown function (DUF1405)
ORP33_10950	COG2010	Cytochrome c
ORP33_10950	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ORP33_10955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ORP33_10960	COG0723	plastoquinol--plastocyanin reductase activity
ORP33_10970	COG5582	Belongs to the UPF0302 family
ORP33_10975	COG0457	Tetratricopeptide repeat
ORP33_10980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ORP33_10985	COG0287	Prephenate dehydrogenase
ORP33_10995	COG0159	tryptophan synthase activity
ORP33_11000	COG0133	tryptophan synthase activity
ORP33_11005	COG0135	phosphoribosylanthranilate isomerase activity
ORP33_11015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ORP33_11020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ORP33_11025	COG4401	Chorismate mutase type I
ORP33_11030	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ORP33_11035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ORP33_11040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ORP33_11045	COG0105	UTP biosynthetic process
ORP33_11050	COG0142	geranyltranstransferase activity
ORP33_11055	COG2226	methyltransferase
ORP33_11060	COG0142	geranyltranstransferase activity
ORP33_11070	COG0302	gtp cyclohydrolase
ORP33_11075	COG0776	regulation of translation
ORP33_11080	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ORP33_11095	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ORP33_11100	COG1160	GTP binding
ORP33_11125	COG1304	FMN binding
ORP33_11130	COG0539	negative regulation of cytoplasmic translation
ORP33_11135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ORP33_11145	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ORP33_11150	COG2959	enzyme of heme biosynthesis
ORP33_11155	COG3409	Peptidoglycan-binding domain 1 protein
ORP33_11155	COG3773	Cell wall hydrolase
ORP33_11160	COG2339	peptidase activity
ORP33_11165	COG0492	ferredoxin-NADP+ reductase activity
ORP33_11170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ORP33_11175	COG4862	establishment of competence for transformation
ORP33_11180	COG1408	metallophosphoesterase
ORP33_11190	COG1388	LysM domain
ORP33_11195	COG1266	CAAX protease self-immunity
ORP33_11200	COG0514	ATP-dependent DNA helicase (RecQ)
ORP33_11205	COG4955	Helix-turn-helix domain
ORP33_11210	COG1141	Ferredoxin
ORP33_11215	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ORP33_11220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ORP33_11225	COG0710	3-dehydroquinate dehydratase activity
ORP33_11235	COG1595	DNA-templated transcription, initiation
ORP33_11240	COG5002	protein histidine kinase activity
ORP33_11245	COG0745	RESPONSE REGULATOR receiver
ORP33_11250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ORP33_11255	COG1333	cytochrome c biogenesis protein
ORP33_11260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ORP33_11265	COG1187	pseudouridine synthase activity
ORP33_11270	COG0700	Nucleoside recognition
ORP33_11275	COG2715	membrane protein required for spore maturation
ORP33_11280	COG1686	Belongs to the peptidase S11 family
ORP33_11290	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ORP33_11295	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ORP33_11300	COG1547	Domain of unknown function (DUF309)
ORP33_11305	COG0456	acetyltransferase
ORP33_11310	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ORP33_11315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ORP33_11315	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ORP33_11320	COG0307	riboflavin synthase, alpha
ORP33_11325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ORP33_11325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ORP33_11335	COG0681	Belongs to the peptidase S26 family
ORP33_11340	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
ORP33_11355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ORP33_11360	COG4086	secreted protein
ORP33_11365	COG0019	diaminopimelate decarboxylase activity
ORP33_11370	COG0697	spore germination
ORP33_11385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ORP33_11405	COG1191	sigma factor activity
ORP33_11410	COG2172	sigma factor antagonist activity
ORP33_11415	COG1366	Belongs to the anti-sigma-factor antagonist family
ORP33_11420	COG1686	Belongs to the peptidase S11 family
ORP33_11425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ORP33_11430	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ORP33_11435	COG4974	Belongs to the 'phage' integrase family
ORP33_11445	COG0735	belongs to the Fur family
ORP33_11450	COG1300	Membrane
ORP33_11460	COG0281	malic enzyme
ORP33_11465	COG1757	Na H antiporter
ORP33_11470	COG1027	Aspartate ammonia-lyase
ORP33_11475	COG0252	asparaginase activity
ORP33_11480	COG1396	sequence-specific DNA binding
ORP33_11485	COG1379	DNA repair
ORP33_11490	COG0494	nUDIX hydrolase
ORP33_11500	COG0667	Aldo Keto reductase
ORP33_11510	COG1073	alpha beta
ORP33_11520	COG4918	Iron-sulphur cluster biosynthesis
ORP33_11525	COG0456	acetyltransferase
ORP33_11525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ORP33_11530	COG2329	Antibiotic biosynthesis monooxygenase
ORP33_11535	COG0456	acetyltransferase
ORP33_11545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ORP33_11555	COG2211	Major facilitator Superfamily
ORP33_11565	COG0346	lactoylglutathione lyase activity
ORP33_11570	COG1072	(Pantothenic acid kinase))
ORP33_11575	COG3048	D-serine ammonia-lyase activity
ORP33_11580	COG0300	oxidoreductase activity
ORP33_11585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ORP33_11590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ORP33_11595	COG4187	Peptidase family M20/M25/M40
ORP33_11600	COG1902	pentaerythritol trinitrate reductase activity
ORP33_11605	COG0596	Alpha beta hydrolase
ORP33_11615	COG1234	tRNA 3'-trailer cleavage
ORP33_11620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ORP33_11625	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ORP33_11630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ORP33_11640	COG0706	membrane insertase activity
ORP33_11645	COG3361	conserved protein (COG2071)
ORP33_11650	COG2195	Cleaves the N-terminal amino acid of tripeptides
ORP33_11655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ORP33_11660	COG0346	lactoylglutathione lyase activity
ORP33_11670	COG1376	ErfK ybiS ycfS ynhG family protein
ORP33_11675	COG4129	membrane
ORP33_11680	COG1126	abc transporter atp-binding protein
ORP33_11685	COG0765	amino acid transport
ORP33_11690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ORP33_11700	COG1597	lipid kinase activity
ORP33_11705	COG2814	Major facilitator Superfamily
ORP33_11710	COG4978	Transcriptional regulator
ORP33_11710	COG0789	Transcriptional regulator
ORP33_11715	COG0508	dehydrogenase complex catalyzes the overall conversion of
ORP33_11720	COG0022	dehydrogenase e1 component
ORP33_11725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ORP33_11730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ORP33_11735	COG3426	butyrate kinase activity
ORP33_11740	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ORP33_11745	COG0280	phosphate acetyltransferase
ORP33_11750	COG3290	protein histidine kinase activity
ORP33_11750	COG3829	transcription factor binding
ORP33_11760	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ORP33_11765	COG2079	MmgE PrpD family protein
ORP33_11770	COG0372	Belongs to the citrate synthase family
ORP33_11775	COG1960	acyl-CoA dehydrogenase activity
ORP33_11780	COG1250	3-hydroxyacyl-CoA dehydrogenase
ORP33_11785	COG0183	Belongs to the thiolase family
ORP33_11790	COG0584	glycerophosphoryl diester phosphodiesterase
ORP33_11795	COG0860	N-Acetylmuramoyl-L-alanine amidase
ORP33_11810	COG1902	pentaerythritol trinitrate reductase activity
ORP33_11815	COG0745	RESPONSE REGULATOR receiver
ORP33_11820	COG0750	zinc metalloprotease
ORP33_11825	COG0497	DNA recombination
ORP33_11830	COG1438	arginine binding
ORP33_11835	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ORP33_11840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ORP33_11845	COG0142	geranyltranstransferase activity
ORP33_11850	COG1722	exodeoxyribonuclease VII activity
ORP33_11855	COG1570	exodeoxyribonuclease VII activity
ORP33_11860	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ORP33_11865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ORP33_11870	COG1302	Protein conserved in bacteria
ORP33_11875	COG0439	Biotin carboxylase
ORP33_11880	COG0511	ligase activity, forming carbon-carbon bonds
ORP33_11920	COG3854	ATPases associated with a variety of cellular activities
ORP33_11930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ORP33_11935	COG0006	proline dipeptidase activity
ORP33_11940	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ORP33_11950	COG3872	metal-dependent enzyme
ORP33_11960	COG1752	Esterase of the alpha-beta hydrolase superfamily
ORP33_11965	COG1321	iron dependent repressor
ORP33_11970	COG0095	Lipoate-protein ligase
ORP33_11975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ORP33_11980	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ORP33_11985	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ORP33_11990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ORP33_11995	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ORP33_12010	COG1396	sequence-specific DNA binding
ORP33_12020	COG0681	Belongs to the peptidase S26 family
ORP33_12045	COG4940	Competence protein ComGF
ORP33_12055	COG4970	Tfp pilus assembly protein FimT
ORP33_12060	COG4537	Required for transformation and DNA binding
ORP33_12065	COG1459	type II secretion system
ORP33_12070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ORP33_12075	COG0517	IMP dehydrogenase activity
ORP33_12080	COG0598	Magnesium transport protein CorA
ORP33_12085	COG1253	flavin adenine dinucleotide binding
ORP33_12090	COG1366	Belongs to the anti-sigma-factor antagonist family
ORP33_12100	COG1393	Belongs to the ArsC family
ORP33_12110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ORP33_12120	COG0011	TIGRFAM Protein of
ORP33_12130	COG2866	Carboxypeptidase
ORP33_12135	COG1368	sulfuric ester hydrolase activity
ORP33_12140	COG1940	carbohydrate kinase activity
ORP33_12145	COG4483	Protein conserved in bacteria
ORP33_12150	COG0705	Rhomboid family
ORP33_12150	COG0457	Tetratricopeptide repeat
ORP33_12160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ORP33_12170	COG0438	transferase activity, transferring glycosyl groups
ORP33_12185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ORP33_12190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ORP33_12195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ORP33_12200	COG0581	inorganic phosphate transmembrane transporter activity
ORP33_12205	COG0573	inorganic phosphate transmembrane transporter activity
ORP33_12210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ORP33_12215	COG0768	penicillin binding
ORP33_12220	COG0477	Major facilitator Superfamily
ORP33_12225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ORP33_12230	COG2839	Protein conserved in bacteria
ORP33_12235	COG5521	maltodextrose utilization protein MalA
ORP33_12240	COG1388	LysM domain
ORP33_12245	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ORP33_12250	COG4709	membrane
ORP33_12255	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
ORP33_12260	COG0735	belongs to the Fur family
ORP33_12265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ORP33_12275	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ORP33_12280	COG0513	Belongs to the DEAD box helicase family
ORP33_12290	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ORP33_12295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ORP33_12300	COG2384	SAM-dependent methyltransferase
ORP33_12305	COG2010	Cytochrome c
ORP33_12310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ORP33_12315	COG0358	DNA primase activity
ORP33_12320	COG1671	Belongs to the UPF0178 family
ORP33_12325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ORP33_12330	COG0517	IMP dehydrogenase activity
ORP33_12335	COG0751	glycine-tRNA ligase activity
ORP33_12340	COG0752	glycyl-tRNA synthetase alpha subunit
ORP33_12345	COG1381	Involved in DNA repair and RecF pathway recombination
ORP33_12355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ORP33_12360	COG0295	cytidine deaminase activity
ORP33_12365	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ORP33_12370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ORP33_12375	COG1480	7TM receptor with intracellular HD hydrolase
ORP33_12380	COG1702	phosphate starvation-inducible protein PhoH
ORP33_12385	COG0561	phosphatase activity
ORP33_12400	COG4864	UPF0365 protein
ORP33_12405	COG1030	water channel activity
ORP33_12410	COG1610	YqeY-like protein
ORP33_12420	COG1283	sodium-dependent phosphate transmembrane transporter activity
ORP33_12425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ORP33_12430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ORP33_12435	COG2264	protein methyltransferase activity
ORP33_12440	COG0484	heat shock protein binding
ORP33_12445	COG0443	Heat shock 70 kDa protein
ORP33_12450	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ORP33_12455	COG1420	regulation of RNA biosynthetic process
ORP33_12460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ORP33_12465	COG0481	GTPase activity
ORP33_12475	COG0860	N-Acetylmuramoyl-L-alanine amidase
ORP33_12480	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ORP33_12485	COG0268	Binds directly to 16S ribosomal RNA
ORP33_12490	COG1466	dna polymerase III delta subunit
ORP33_12500	COG0658	competence protein
ORP33_12500	COG2333	competence protein COMEC
ORP33_12505	COG2131	deaminase
ORP33_12510	COG1555	photosystem II stabilization
ORP33_12510	COG1596	polysaccharide export
ORP33_12515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ORP33_12520	COG2226	methyltransferase
ORP33_12525	COG0799	negative regulation of ribosome biogenesis
ORP33_12530	COG1713	HD superfamily hydrolase involved in NAD metabolism
ORP33_12535	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ORP33_12540	COG1534	Rna-binding protein
ORP33_12545	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ORP33_12550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ORP33_12555	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ORP33_12565	COG2755	lipolytic protein G-D-S-L family
ORP33_12570	COG3409	Peptidoglycan-binding domain 1 protein
ORP33_12570	COG5632	N-Acetylmuramoyl-L-alanine amidase
ORP33_12575	COG0398	Pfam SNARE associated Golgi protein
ORP33_12580	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ORP33_12590	COG3209	COG3209 Rhs family protein
ORP33_12600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ORP33_12605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ORP33_12610	COG0798	PFAM Bile acid sodium symporter
ORP33_12615	COG0346	lactoylglutathione lyase activity
ORP33_12620	COG0640	Transcriptional regulator
ORP33_12625	COG3403	YqcI/YcgG family
ORP33_12630	COG0457	Tetratricopeptide repeat
ORP33_12645	COG5444	nuclease activity
ORP33_12670	COG5632	N-Acetylmuramoyl-L-alanine amidase
ORP33_12670	COG3409	Peptidoglycan-binding domain 1 protein
ORP33_12675	COG4824	toxin secretion phage lysis holin
ORP33_12705	COG3778	Protein conserved in bacteria
ORP33_12710	COG3299	homolog of phage Mu protein gp47
ORP33_12715	COG3628	GPW Gp25 family protein
ORP33_12725	COG4193	domain, Protein
ORP33_12730	COG1652	LysM domain
ORP33_12735	COG5280	Phage tail tape measure protein TP901
ORP33_12735	COG3953	SLT domain
ORP33_12790	COG4653	Phage capsid family
ORP33_12795	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ORP33_12805	COG2369	cell adhesion
ORP33_12810	COG5518	Phage portal protein
ORP33_12815	COG1783	phage Terminase large subunit
ORP33_12820	COG5484	DNA packaging
ORP33_12830	COG3677	Transposase
ORP33_12845	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ORP33_12855	COG1484	DNA-dependent DNA replication
ORP33_12860	COG3935	DnaD domain protein
ORP33_12865	COG3723	Recombinational DNA repair protein, rece pathway
ORP33_12870	COG5377	YqaJ viral recombinase family
ORP33_12895	COG1476	TRANSCRIPTIONal
ORP33_12900	COG3620	sequence-specific DNA binding
ORP33_12910	COG0563	adenylate kinase activity
ORP33_12915	COG2856	Zn peptidase
ORP33_12935	COG4124	Belongs to the glycosyl hydrolase 26 family
ORP33_12940	COG0730	response to heat
ORP33_12945	COG0425	Belongs to the sulfur carrier protein TusA family
ORP33_12950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ORP33_12950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ORP33_12955	COG0425	Belongs to the sulfur carrier protein TusA family
ORP33_12955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ORP33_12960	COG2210	Belongs to the sulfur carrier protein TusA family
ORP33_12965	COG1937	Protein conserved in bacteria
ORP33_12970	COG0662	Cupin 2, conserved barrel domain protein
ORP33_12975	COG0789	Transcriptional regulator
ORP33_12975	COG4978	Transcriptional regulator
ORP33_12980	COG2814	Major facilitator Superfamily
ORP33_12985	COG0456	acetyltransferase
ORP33_12990	COG1253	flavin adenine dinucleotide binding
ORP33_13000	COG0697	spore germination
ORP33_13005	COG0583	DNA-binding transcription factor activity
ORP33_13010	COG2072	flavoprotein involved in K transport
ORP33_13015	COG1230	cation diffusion facilitator family transporter
ORP33_13020	COG1942	4-Oxalocrotonate Tautomerase
ORP33_13025	COG0583	DNA-binding transcription factor activity
ORP33_13030	COG1114	Component of the transport system for branched-chain amino acids
ORP33_13035	COG1687	branched-chain amino acid
ORP33_13040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ORP33_13045	COG1522	sequence-specific DNA binding
ORP33_13050	COG2732	(Barnase) inhibitor
ORP33_13055	COG2124	cytochrome p450
ORP33_13065	COG1335	isochorismatase
ORP33_13075	COG2318	DinB family
ORP33_13085	COG2070	2-Nitropropane dioxygenase
ORP33_13090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ORP33_13105	COG3443	Belongs to the bacterial solute-binding protein 9 family
ORP33_13110	COG1595	DNA-templated transcription, initiation
ORP33_13115	COG0667	Aldo Keto reductase
ORP33_13120	COG2851	Citrate transporter
ORP33_13125	COG0583	DNA-binding transcription factor activity
ORP33_13130	COG2828	Protein conserved in bacteria
ORP33_13135	COG3409	Peptidoglycan-binding domain 1 protein
ORP33_13140	COG5566	PFAM Mor transcription activator
ORP33_13145	COG0596	Alpha beta hydrolase
ORP33_13150	COG4991	sh3 domain protein
ORP33_13155	COG4991	sh3 domain protein
ORP33_13160	COG0346	lactoylglutathione lyase activity
ORP33_13170	COG5577	PFAM Coat F domain
ORP33_13175	COG1063	alcohol dehydrogenase
ORP33_13180	COG1063	alcohol dehydrogenase
ORP33_13190	COG5577	PFAM Coat F domain
ORP33_13195	COG0789	Transcriptional regulator
ORP33_13200	COG1064	alcohol dehydrogenase
ORP33_13205	COG0693	protein deglycase activity
ORP33_13210	COG1621	beta-fructofuranosidase activity
ORP33_13215	COG3716	PTS system mannose fructose sorbose family IID component
ORP33_13220	COG3715	PTS system
ORP33_13225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ORP33_13230	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ORP33_13235	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ORP33_13235	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ORP33_13240	COG1113	amino acid transport
ORP33_13245	COG1280	lysine exporter protein (LysE YggA)
ORP33_13250	COG1378	Sugar-specific transcriptional regulator TrmB
ORP33_13255	COG1595	DNA-templated transcription, initiation
ORP33_13275	COG2124	cytochrome p450
ORP33_13275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ORP33_13280	COG1309	transcriptional regulator
ORP33_13285	COG2226	methyltransferase
ORP33_13300	COG2116	formate transmembrane transporter activity
ORP33_13305	COG5609	conserved protein (DUF2294)
ORP33_13310	COG3383	formate dehydrogenase (NAD+) activity
ORP33_13315	COG2427	Protein of unknown function (DUF1641)
ORP33_13325	COG0626	cystathionine gamma-synthase activity
ORP33_13330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ORP33_13335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ORP33_13340	COG2226	methyltransferase
ORP33_13355	COG0768	penicillin binding
ORP33_13360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ORP33_13365	COG0572	uridine kinase
ORP33_13370	COG0826	peptidase U32
ORP33_13375	COG0826	peptidase U32
ORP33_13380	COG4122	O-methyltransferase activity
ORP33_13385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ORP33_13390	COG3906	Belongs to the UPF0473 family
ORP33_13395	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ORP33_13400	COG4472	Bacterial protein of unknown function (DUF965)
ORP33_13405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ORP33_13410	COG0628	permease
ORP33_13415	COG1126	abc transporter atp-binding protein
ORP33_13420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ORP33_13425	COG0765	amino acid transport
ORP33_13430	COG0765	amino acid transport
ORP33_13445	COG3881	PFAM PRC-barrel domain
ORP33_13450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ORP33_13455	COG0457	Tetratricopeptide repeat
ORP33_13460	COG0482	sulfurtransferase activity
ORP33_13465	COG1104	cysteine desulfurase activity
ORP33_13470	COG1959	2 iron, 2 sulfur cluster binding
ORP33_13475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ORP33_13480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ORP33_13490	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ORP33_13495	COG0124	histidyl-tRNA synthetase
ORP33_13505	COG0860	N-Acetylmuramoyl-L-alanine amidase
ORP33_13505	COG3103	Sh3 type 3 domain protein
ORP33_13505	COG4991	sh3 domain protein
ORP33_13510	COG1490	D-aminoacyl-tRNA deacylase activity
ORP33_13515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ORP33_13520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ORP33_13525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ORP33_13525	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ORP33_13530	COG5416	Lipopolysaccharide assembly protein A domain
ORP33_13535	COG0490	domain, Protein
ORP33_13540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ORP33_13540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ORP33_13550	COG2244	polysaccharide biosynthetic process
ORP33_13555	COG2323	membrane
ORP33_13565	COG1862	Preprotein translocase
ORP33_13570	COG0343	queuine tRNA-ribosyltransferase activity
ORP33_13575	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ORP33_13585	COG2255	four-way junction helicase activity
ORP33_13590	COG0632	four-way junction helicase activity
ORP33_13600	COG2814	Major facilitator Superfamily
ORP33_13605	COG0673	inositol 2-dehydrogenase activity
ORP33_13610	COG2112	serine threonine protein kinase
ORP33_13630	COG1115	amino acid carrier protein
ORP33_13635	COG0217	transcriptional regulatory protein
ORP33_13645	COG1388	LysM domain
ORP33_13650	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ORP33_13655	COG0157	Belongs to the NadC ModD family
ORP33_13660	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ORP33_13665	COG1104	cysteine desulfurase activity
ORP33_13670	COG1827	regulation of RNA biosynthetic process
ORP33_13675	COG0077	Prephenate dehydratase
ORP33_13680	COG4492	Belongs to the UPF0735 family
ORP33_13685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ORP33_13690	COG3290	protein histidine kinase activity
ORP33_13695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ORP33_13700	COG2868	ribosomal protein
ORP33_13705	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ORP33_13710	COG1994	Peptidase M50
ORP33_13715	COG0739	heme binding
ORP33_13720	COG2894	cell division
ORP33_13725	COG0850	regulation of cytokinetic process
ORP33_13730	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ORP33_13740	COG1077	Cell shape determining protein MreB Mrl
ORP33_13745	COG2003	Belongs to the UPF0758 family
ORP33_13750	COG0424	maF-like protein
ORP33_13760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ORP33_13765	COG0285	dihydrofolate synthase activity
ORP33_13770	COG0525	valine-tRNA ligase activity
ORP33_13780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ORP33_13785	COG1388	LysM domain
ORP33_13790	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ORP33_13795	COG0113	porphobilinogen synthase activity
ORP33_13800	COG1587	Uroporphyrinogen-III synthase
ORP33_13805	COG0181	hydroxymethylbilane synthase activity
ORP33_13810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ORP33_13815	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ORP33_13825	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ORP33_13830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ORP33_13835	COG1067	ATP-dependent peptidase activity
ORP33_13835	COG0470	DNA polymerase III
ORP33_13840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ORP33_13845	COG0544	peptidyl-prolyl cis-trans isomerase activity
ORP33_13850	COG0457	Tetratricopeptide repeat
ORP33_13850	COG1477	protein flavinylation
ORP33_13855	COG0066	3-isopropylmalate dehydratase activity
ORP33_13860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ORP33_13865	COG0473	3-isopropylmalate dehydrogenase activity
ORP33_13870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ORP33_13875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ORP33_13880	COG0440	acetolactate synthase activity
ORP33_13885	COG0028	Belongs to the TPP enzyme family
ORP33_13895	COG0454	-acetyltransferase
ORP33_13900	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
ORP33_13910	COG0622	Phosphoesterase
ORP33_13915	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ORP33_13920	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ORP33_13925	COG5401	PFAM Sporulation and spore germination
ORP33_13930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ORP33_13935	COG1846	Transcriptional regulator
ORP33_13940	COG2197	response regulator
ORP33_13945	COG0824	Thioesterase
ORP33_13950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ORP33_13955	COG1053	succinate dehydrogenase
ORP33_13960	COG2009	succinate dehydrogenase
ORP33_13965	COG1719	4-vinyl reductase, 4VR
ORP33_13970	COG0527	aspartate kinase activity
ORP33_13975	COG0322	excinuclease ABC activity
ORP33_13980	COG3118	belongs to the thioredoxin family
ORP33_13985	COG3534	alpha-L-arabinofuranosidase
ORP33_13990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ORP33_13995	COG2086	electron transfer activity
ORP33_14000	COG1024	Enoyl-CoA hydratase
ORP33_14005	COG1309	transcriptional regulator
ORP33_14010	COG0318	PFAM AMP-dependent synthetase and ligase
ORP33_14015	COG3766	membrane
ORP33_14020	COG1193	negative regulation of DNA recombination
ORP33_14025	COG1796	DNA polymerase
ORP33_14025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ORP33_14030	COG1286	toxin biosynthetic process
ORP33_14035	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ORP33_14040	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ORP33_14045	COG0072	phenylalanine-tRNA ligase activity
ORP33_14045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ORP33_14050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ORP33_14055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ORP33_14065	COG3835	regulator
ORP33_14070	COG0277	FAD linked oxidase domain protein
ORP33_14075	COG0247	lactate metabolic process
ORP33_14080	COG0346	lactoylglutathione lyase activity
ORP33_14085	COG1966	Carbon starvation protein
ORP33_14090	COG3534	alpha-L-arabinofuranosidase
ORP33_14095	COG0395	ABC-type sugar transport system, permease component
ORP33_14100	COG1175	transmembrane transport
ORP33_14105	COG1653	transport
ORP33_14110	COG0371	Dehydrogenase
ORP33_14115	COG0647	UMP catabolic process
ORP33_14120	COG0235	Class ii aldolase
ORP33_14125	COG1069	ribulokinase activity
ORP33_14130	COG2160	L-arabinose isomerase activity
ORP33_14135	COG3507	Belongs to the glycosyl hydrolase 43 family
ORP33_14140	COG1363	Peptidase, m42
ORP33_14150	COG3326	Membrane
ORP33_14155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ORP33_14160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ORP33_14165	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ORP33_14175	COG1346	cytolysis
ORP33_14180	COG1380	Effector of murein hydrolase LrgA
ORP33_14185	COG3279	Response regulator of the LytR AlgR family
ORP33_14190	COG3275	phosphorelay sensor kinase activity
ORP33_14195	COG1011	Hydrolase
ORP33_14200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ORP33_14210	COG0398	Pfam SNARE associated Golgi protein
ORP33_14215	COG1484	DNA-dependent DNA replication
ORP33_14220	COG3611	Membrane attachment protein
ORP33_14225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ORP33_14230	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ORP33_14235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ORP33_14240	COG1733	regulation of RNA biosynthetic process
ORP33_14245	COG2814	Major facilitator Superfamily
ORP33_14250	COG0656	L-ascorbic acid biosynthetic process
ORP33_14255	COG0237	dephospho-CoA kinase activity
ORP33_14265	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ORP33_14270	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ORP33_14270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ORP33_14275	COG5002	protein histidine kinase activity
ORP33_14280	COG0745	RESPONSE REGULATOR receiver
ORP33_14285	COG0039	L-malate dehydrogenase activity
ORP33_14290	COG0538	isocitrate dehydrogenase activity
ORP33_14295	COG0372	Belongs to the citrate synthase family
ORP33_14300	COG2707	UPF0756 membrane protein
ORP33_14305	COG0628	permease
ORP33_14310	COG3030	protein affecting phage T7 exclusion by the F plasmid
ORP33_14315	COG0469	pyruvate kinase activity
ORP33_14320	COG0205	6-phosphofructokinase activity
ORP33_14325	COG0825	malonyl-CoA metabolic process
ORP33_14330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ORP33_14335	COG0281	malic enzyme
ORP33_14340	COG0587	DNA-directed DNA polymerase activity
ORP33_14360	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ORP33_14370	COG4109	DRTGG domain
ORP33_14375	COG0730	response to heat
ORP33_14380	COG1473	amidohydrolase
ORP33_14385	COG0196	riboflavin kinase activity
ORP33_14390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ORP33_14395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ORP33_14400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ORP33_14405	COG1126	abc transporter atp-binding protein
ORP33_14410	COG0765	amino acid transport
ORP33_14415	COG0765	amino acid transport
ORP33_14420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ORP33_14425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ORP33_14430	COG0454	-acetyltransferase
ORP33_14435	COG0583	DNA-binding transcription factor activity
ORP33_14440	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ORP33_14445	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_14455	COG0165	Argininosuccinate lyase
ORP33_14460	COG0137	argininosuccinate synthase activity
ORP33_14465	COG0521	Mo-molybdopterin cofactor biosynthetic process
ORP33_14470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ORP33_14475	COG0827	DNA restriction-modification system
ORP33_14480	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ORP33_14485	COG3874	Sporulation protein YtfJ
ORP33_14495	COG1714	RDD family
ORP33_14500	COG0616	signal peptide processing
ORP33_14505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ORP33_14510	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ORP33_14515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ORP33_14525	COG0301	tRNA thio-modification
ORP33_14530	COG1104	cysteine desulfurase activity
ORP33_14535	COG1114	Component of the transport system for branched-chain amino acids
ORP33_14540	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ORP33_14545	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ORP33_14550	COG1309	transcriptional regulator
ORP33_14555	COG1956	GAF domain-containing protein
ORP33_14560	COG2203	Gaf domain
ORP33_14560	COG2199	diguanylate cyclase activity
ORP33_14565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ORP33_14575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ORP33_14580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ORP33_14585	COG0454	-acetyltransferase
ORP33_14590	COG0517	IMP dehydrogenase activity
ORP33_14595	COG0123	including yeast histone deacetylase and acetoin utilization protein
ORP33_14600	COG1360	Flagellar Motor Protein
ORP33_14605	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ORP33_14610	COG1609	Transcriptional regulator
ORP33_14615	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ORP33_14615	COG1605	Chorismate mutase
ORP33_14620	COG3118	belongs to the thioredoxin family
ORP33_14625	COG4980	gas vesicle protein
ORP33_14630	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ORP33_14635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ORP33_14640	COG1674	ftsk spoiiie
ORP33_14645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ORP33_14650	COG4848	Belongs to the UPF0354 family
ORP33_14655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ORP33_14665	COG1363	Peptidase, m42
ORP33_14670	COG5584	Small secreted protein
ORP33_14675	COG0281	malic enzyme
ORP33_14680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ORP33_14685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ORP33_14695	COG0510	thiamine kinase activity
ORP33_14700	COG1523	belongs to the glycosyl hydrolase 13 family
ORP33_14705	COG1597	lipid kinase activity
ORP33_14715	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ORP33_14720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ORP33_14725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ORP33_14730	COG2252	PERMEase
ORP33_14735	COG4473	ABC transporter
ORP33_14740	COG1131	(ABC) transporter
ORP33_14745	COG1349	DNA-binding transcription factor activity
ORP33_14750	COG1187	pseudouridine synthase activity
ORP33_14755	COG2244	polysaccharide biosynthetic process
ORP33_14760	COG2081	HI0933 family
ORP33_14765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ORP33_14775	COG5578	integral membrane protein
ORP33_14780	COG0673	inositol 2-dehydrogenase activity
ORP33_14785	COG1653	transport
ORP33_14790	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ORP33_14795	COG4209	transmembrane transport
ORP33_14800	COG2207	Transcriptional regulator
ORP33_14805	COG1653	transport
ORP33_14810	COG0395	ABC-type sugar transport system, permease component
ORP33_14815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ORP33_14820	COG2124	cytochrome p450
ORP33_14835	COG0156	8-amino-7-oxononanoate synthase activity
ORP33_14840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ORP33_14850	COG1073	alpha beta
ORP33_14855	COG1609	Transcriptional regulator
ORP33_14860	COG1653	transport
ORP33_14865	COG1175	transmembrane transport
ORP33_14870	COG0395	ABC-type sugar transport system, permease component
ORP33_14875	COG1486	melibiose metabolic process
ORP33_14880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ORP33_14885	COG0495	leucyl-tRNA aminoacylation
ORP33_14895	COG1366	Belongs to the anti-sigma-factor antagonist family
ORP33_14895	COG2202	Pas domain
ORP33_14900	COG2814	Major facilitator Superfamily
ORP33_14905	COG2433	Pfam Transposase IS66
ORP33_14910	COG0577	efflux transmembrane transporter activity
ORP33_14915	COG1136	(ABC) transporter
ORP33_14920	COG2205	protein histidine kinase activity
ORP33_14925	COG0745	RESPONSE REGULATOR receiver
ORP33_14930	COG0577	efflux transmembrane transporter activity
ORP33_14935	COG1136	(ABC) transporter
ORP33_14950	COG1131	(ABC) transporter
ORP33_14955	COG1725	Transcriptional regulator
ORP33_14970	COG1242	4 iron, 4 sulfur cluster binding
ORP33_14975	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ORP33_14985	COG2267	carboxylic ester hydrolase activity
ORP33_14990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ORP33_14995	COG1113	amino acid transport
ORP33_15000	COG0367	asparagine synthase
ORP33_15005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ORP33_15010	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ORP33_15020	COG1506	peptidase
ORP33_15025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ORP33_15030	COG1116	anion transmembrane transporter activity
ORP33_15035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ORP33_15040	COG0494	nUDIX hydrolase
ORP33_15045	COG4824	toxin secretion phage lysis holin
ORP33_15050	COG0783	Belongs to the Dps family
ORP33_15065	COG1854	S-ribosylhomocysteine lyase activity
ORP33_15070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ORP33_15075	COG0288	reversible hydration of carbon dioxide
ORP33_15080	COG0254	rRNA binding
ORP33_15085	COG1271	oxidase subunit
ORP33_15090	COG1294	oxidase, subunit
ORP33_15100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ORP33_15105	COG1321	iron dependent repressor
ORP33_15105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ORP33_15110	COG1121	(ABC) transporter
ORP33_15115	COG0803	Belongs to the bacterial solute-binding protein 9 family
ORP33_15120	COG4948	Mandelate Racemase Muconate Lactonizing
ORP33_15125	COG0318	PFAM AMP-dependent synthetase and ligase
ORP33_15130	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ORP33_15135	COG0596	Alpha beta hydrolase
ORP33_15140	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ORP33_15145	COG1169	isochorismate synthase
ORP33_15150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ORP33_15155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ORP33_15160	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ORP33_15165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ORP33_15170	COG0438	transferase activity, transferring glycosyl groups
ORP33_15180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ORP33_15185	COG0438	transferase activity, transferring glycosyl groups
ORP33_15190	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ORP33_15195	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ORP33_15200	COG0058	SHG alpha-glucan phosphorylase activity
ORP33_15205	COG0297	glycogen (starch) synthase activity
ORP33_15210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ORP33_15215	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ORP33_15220	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ORP33_15345	COG3859	Proton-coupled thiamine transporter YuaJ
ORP33_15350	COG1247	-acetyltransferase
ORP33_15355	COG2268	Band 7 protein
ORP33_15360	COG1585	Membrane protein implicated in regulation of membrane protease activity
ORP33_15365	COG2318	DinB family
ORP33_15375	COG1454	alcohol dehydrogenase
ORP33_15380	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_15385	COG1510	regulation of RNA biosynthetic process
ORP33_15395	COG0569	domain protein
ORP33_15400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ORP33_15405	COG4682	membrane
ORP33_15410	COG1705	Flagellar rod assembly protein muramidase FlgJ
ORP33_15415	COG0477	Major facilitator Superfamily
ORP33_15420	COG5553	Cysteine dioxygenase type I
ORP33_15430	COG1968	undecaprenyl-diphosphatase activity
ORP33_15435	COG0628	permease
ORP33_15440	COG0673	inositol 2-dehydrogenase activity
ORP33_15445	COG4806	L-rhamnose isomerase
ORP33_15450	COG3254	rhamnose metabolic process
ORP33_15455	COG1070	Carbohydrate kinase
ORP33_15460	COG1349	DNA-binding transcription factor activity
ORP33_15465	COG3347	Dehydrogenase
ORP33_15465	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_15470	COG0840	transmembrane signaling receptor activity
ORP33_15475	COG0840	transmembrane signaling receptor activity
ORP33_15490	COG0432	Pfam Uncharacterised protein family UPF0047
ORP33_15495	COG0366	Alpha amylase catalytic
ORP33_15500	COG1253	flavin adenine dinucleotide binding
ORP33_15505	COG2738	Putative neutral zinc metallopeptidase
ORP33_15520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ORP33_15535	COG0166	Belongs to the GPI family
ORP33_15540	COG1979	alcohol dehydrogenase
ORP33_15545	COG1979	alcohol dehydrogenase
ORP33_15550	COG2155	Conserved Protein
ORP33_15555	COG1098	S1 RNA binding domain
ORP33_15560	COG0436	Aminotransferase
ORP33_15565	COG1522	sequence-specific DNA binding
ORP33_15570	COG2267	carboxylic ester hydrolase activity
ORP33_15580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ORP33_15585	COG2205	protein histidine kinase activity
ORP33_15595	COG5018	Exonuclease
ORP33_15600	COG2814	Major facilitator Superfamily
ORP33_15605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ORP33_15610	COG3011	Protein conserved in bacteria
ORP33_15620	COG3290	protein histidine kinase activity
ORP33_15625	COG4565	transcriptional regulatory protein
ORP33_15630	COG1744	ABC transporter substrate-binding protein PnrA-like
ORP33_15635	COG3845	ABC transporter
ORP33_15640	COG4603	Belongs to the binding-protein-dependent transport system permease family
ORP33_15645	COG1079	Belongs to the binding-protein-dependent transport system permease family
ORP33_15650	COG3493	citrate carrier protein
ORP33_15660	COG2111	Na H antiporter
ORP33_15660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ORP33_15665	COG2111	Na H antiporter
ORP33_15670	COG1006	Multisubunit Na H antiporter MnhC subunit
ORP33_15675	COG0651	ATP synthesis coupled electron transport
ORP33_15680	COG1863	multisubunit Na H antiporter MnhE subunit
ORP33_15685	COG2212	antiporter activity
ORP33_15690	COG1320	monovalent cation:proton antiporter activity
ORP33_15695	COG2050	protein possibly involved in aromatic compounds catabolism
ORP33_15700	COG2197	response regulator
ORP33_15705	COG4585	Histidine kinase
ORP33_15715	COG0142	geranyltranstransferase activity
ORP33_15730	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ORP33_15735	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ORP33_15740	COG1335	isochorismatase
ORP33_15745	COG5506	Protein of unknown function (DUF1694)
ORP33_15760	COG0628	permease
ORP33_15775	COG1418	mRNA catabolic process
ORP33_15780	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_15790	COG1511	domain protein
ORP33_15795	COG1674	ftsk spoiiie
ORP33_15795	COG0433	COG0433 Predicted ATPase
ORP33_15800	COG4499	WXG100 protein secretion system (Wss), protein YukC
ORP33_15805	COG5417	Belongs to the EsaB family
ORP33_15810	COG4842	Belongs to the WXG100 family
ORP33_15815	COG2508	Transcriptional regulator
ORP33_15815	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ORP33_15820	COG0686	Belongs to the AlaDH PNT family
ORP33_15825	COG5634	Uncharacterized conserved protein (DUF2278)
ORP33_15830	COG3251	PFAM MbtH domain protein
ORP33_15835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_15840	COG3433	isochorismatase activity
ORP33_15840	COG1535	isochorismatase
ORP33_15845	COG1021	2,3-dihydroxybenzoate-AMP ligase
ORP33_15850	COG1169	isochorismate synthase
ORP33_15855	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_15860	COG2819	hydrolase of the alpha beta superfamily
ORP33_15865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ORP33_15870	COG1268	BioY protein
ORP33_15875	COG2056	Na+-H+ antiporter family
ORP33_15880	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ORP33_15885	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ORP33_15890	COG3584	3D domain protein
ORP33_15905	COG1252	NADH dehydrogenase
ORP33_15910	COG0492	ferredoxin-NADP+ reductase activity
ORP33_15920	COG0516	GMP reductase activity
ORP33_15930	COG2808	Putative FMN-binding domain
ORP33_15935	COG0456	acetyltransferase
ORP33_15940	COG0316	Belongs to the HesB IscA family
ORP33_15945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ORP33_15950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ORP33_15955	COG4844	belongs to the
ORP33_15960	COG1252	NADH dehydrogenase
ORP33_15965	COG4837	Protein of unknown function (DUF1462)
ORP33_15970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ORP33_15975	COG0823	Involved in the tonB-independent uptake of proteins
ORP33_15975	COG1506	peptidase
ORP33_15975	COG4946	Tricorn protease homolog
ORP33_15980	COG0083	homoserine kinase activity
ORP33_15985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ORP33_15990	COG0460	homoserine dehydrogenase
ORP33_15995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ORP33_16000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ORP33_16005	COG0647	UMP catabolic process
ORP33_16010	COG2445	Protein of unknown function DUF86
ORP33_16015	COG4470	Protein conserved in bacteria
ORP33_16025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ORP33_16030	COG0739	heme binding
ORP33_16040	COG3377	Domain of unknown function (DUF1805)
ORP33_16045	COG0737	Belongs to the 5'-nucleotidase family
ORP33_16050	COG0730	response to heat
ORP33_16055	COG1801	Protein of unknown function DUF72
ORP33_16065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ORP33_16070	COG2508	Transcriptional regulator
ORP33_16075	COG2233	PERMEase
ORP33_16080	COG2233	PERMEase
ORP33_16085	COG3648	Uricase
ORP33_16085	COG3195	allantoin biosynthetic process
ORP33_16090	COG2351	hydroxyisourate hydrolase activity
ORP33_16100	COG2080	2 iron, 2 sulfur cluster binding
ORP33_16105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ORP33_16110	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ORP33_16115	COG2068	MobA-Related Protein
ORP33_16120	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ORP33_16125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ORP33_16130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ORP33_16135	COG2356	endonuclease I
ORP33_16140	COG3842	ATPase activity
ORP33_16145	COG2188	Transcriptional regulator
ORP33_16150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ORP33_16155	COG0395	ABC-type sugar transport system, permease component
ORP33_16160	COG1175	transmembrane transport
ORP33_16165	COG1653	transport
ORP33_16170	COG2222	sugar isomerase
ORP33_16175	COG0322	excinuclease ABC activity
ORP33_16180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ORP33_16195	COG0719	Fe-S assembly protein
ORP33_16200	COG0822	iron-sulfur transferase activity
ORP33_16205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ORP33_16210	COG0719	Fe-S assembly protein
ORP33_16215	COG0396	ATPase activity
ORP33_16225	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ORP33_16230	COG1464	Belongs to the NlpA lipoprotein family
ORP33_16235	COG2011	ABC-type metal ion transport system permease component
ORP33_16240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ORP33_16250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ORP33_16255	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ORP33_16265	COG0509	glycine decarboxylation via glycine cleavage system
ORP33_16270	COG1393	Belongs to the ArsC family
ORP33_16275	COG1960	acyl-CoA dehydrogenase activity
ORP33_16280	COG0183	Belongs to the thiolase family
ORP33_16285	COG1024	Enoyl-CoA hydratase
ORP33_16285	COG1250	3-hydroxyacyl-CoA dehydrogenase
ORP33_16295	COG0506	proline dehydrogenase activity
ORP33_16305	COG5577	PFAM Coat F domain
ORP33_16310	COG1846	Transcriptional regulator
ORP33_16315	COG0477	Major facilitator Superfamily
ORP33_16320	COG1942	4-Oxalocrotonate Tautomerase
ORP33_16325	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_16330	COG0583	DNA-binding transcription factor activity
ORP33_16340	COG1120	ATPase activity
ORP33_16355	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_16360	COG0783	Belongs to the Dps family
ORP33_16365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ORP33_16370	COG0745	RESPONSE REGULATOR receiver
ORP33_16375	COG2205	protein histidine kinase activity
ORP33_16375	COG2770	Histidine kinase
ORP33_16385	COG1309	transcriptional regulator
ORP33_16390	COG0114	fumarate hydratase activity
ORP33_16400	COG0697	spore germination
ORP33_16405	COG0814	amino acid
ORP33_16415	COG2197	response regulator
ORP33_16420	COG4585	Histidine kinase
ORP33_16425	COG4758	membrane
ORP33_16430	COG3595	metallopeptidase activity
ORP33_16435	COG1842	Phage shock protein A
ORP33_16440	COG4758	membrane
ORP33_16445	COG2814	Major facilitator Superfamily
ORP33_16450	COG2096	Adenosyltransferase
ORP33_16455	COG1120	ATPase activity
ORP33_16460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ORP33_16465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ORP33_16470	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_16475	COG3386	PFAM SMP-30 Gluconolaconase
ORP33_16480	COG2205	protein histidine kinase activity
ORP33_16485	COG0745	RESPONSE REGULATOR receiver
ORP33_16495	COG1191	sigma factor activity
ORP33_16505	COG2140	Oxalate decarboxylase
ORP33_16515	COG0577	efflux transmembrane transporter activity
ORP33_16520	COG1136	(ABC) transporter
ORP33_16525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ORP33_16530	COG1120	ATPase activity
ORP33_16535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ORP33_16540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ORP33_16545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ORP33_16550	COG0531	amino acid
ORP33_16560	COG1988	membrane-bound metal-dependent
ORP33_16565	COG1368	sulfuric ester hydrolase activity
ORP33_16570	COG1910	domain protein
ORP33_16580	COG0725	ABC transporter, periplasmic molybdate-binding protein
ORP33_16585	COG4149	molybdate abc transporter
ORP33_16590	COG0656	L-ascorbic acid biosynthetic process
ORP33_16600	COG0025	NhaP-type Na H and K H
ORP33_16605	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ORP33_16610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ORP33_16615	COG3973	AAA domain
ORP33_16625	COG2860	membrane
ORP33_16630	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ORP33_16635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ORP33_16640	COG2217	Heavy metal translocating P-type atpase
ORP33_16645	COG2217	Heavy metal translocating P-type atpase
ORP33_16650	COG2608	mercury ion transmembrane transporter activity
ORP33_16655	COG1937	Protein conserved in bacteria
ORP33_16660	COG0673	inositol 2-dehydrogenase activity
ORP33_16665	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ORP33_16670	COG1289	transmembrane transporter activity
ORP33_16680	COG2076	Multidrug Resistance protein
ORP33_16685	COG1309	transcriptional regulator
ORP33_16690	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_16700	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ORP33_16705	COG0557	exoribonuclease II activity
ORP33_16710	COG1647	Serine aminopeptidase, S33
ORP33_16715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ORP33_16720	COG0596	Alpha beta hydrolase
ORP33_16725	COG1476	TRANSCRIPTIONal
ORP33_16730	COG1396	sequence-specific DNA binding
ORP33_16735	COG1396	sequence-specific DNA binding
ORP33_16740	COG1733	regulation of RNA biosynthetic process
ORP33_16745	COG0840	transmembrane signaling receptor activity
ORP33_16750	COG1174	glycine betaine transport
ORP33_16755	COG1732	Glycine betaine
ORP33_16760	COG1174	glycine betaine transport
ORP33_16765	COG1125	glycine betaine transport
ORP33_16765	COG0517	IMP dehydrogenase activity
ORP33_16770	COG1510	regulation of RNA biosynthetic process
ORP33_16775	COG1174	glycine betaine transport
ORP33_16780	COG1732	Glycine betaine
ORP33_16785	COG1174	glycine betaine transport
ORP33_16790	COG0517	IMP dehydrogenase activity
ORP33_16790	COG1125	glycine betaine transport
ORP33_16795	COG1510	regulation of RNA biosynthetic process
ORP33_16800	COG2095	MarC family integral membrane protein
ORP33_16810	COG3064	Membrane
ORP33_16815	COG4640	response to antibiotic
ORP33_16820	COG0456	acetyltransferase
ORP33_16825	COG0148	phosphopyruvate hydratase activity
ORP33_16830	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ORP33_16835	COG0149	triose-phosphate isomerase activity
ORP33_16840	COG0126	phosphoglycerate kinase activity
ORP33_16845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ORP33_16850	COG2390	Transcriptional regulator
ORP33_16855	COG2814	Major facilitator Superfamily
ORP33_16860	COG1609	Transcriptional regulator
ORP33_16865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ORP33_16870	COG0583	DNA-binding transcription factor activity
ORP33_16875	COG0697	spore germination
ORP33_16880	COG1113	amino acid transport
ORP33_16885	COG3858	chitin binding
ORP33_16890	COG1556	Lactate utilization protein
ORP33_16895	COG1139	Iron-sulfur cluster binding protein
ORP33_16900	COG0247	lactate metabolic process
ORP33_16905	COG2197	response regulator
ORP33_16910	COG4585	Histidine kinase
ORP33_16915	COG0842	Transport permease protein
ORP33_16920	COG1131	(ABC) transporter
ORP33_16925	COG0596	Alpha beta hydrolase
ORP33_16930	COG2208	phosphoserine phosphatase activity
ORP33_16935	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ORP33_16940	COG1874	Beta-galactosidase
ORP33_16945	COG3833	ABC-type maltose transport systems, permease component
ORP33_16950	COG1175	transmembrane transport
ORP33_16955	COG2182	Extracellular solute-binding protein
ORP33_16960	COG1609	Transcriptional regulator
ORP33_16965	COG2186	Transcriptional regulator
ORP33_16970	COG1620	l-lactate permease
ORP33_16975	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ORP33_16985	COG5039	Polysaccharide pyruvyl transferase
ORP33_16990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ORP33_16995	COG0110	maltose O-acetyltransferase activity
ORP33_17000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ORP33_17005	COG2244	polysaccharide biosynthetic process
ORP33_17010	COG1216	Glycosyl transferase, family 2
ORP33_17015	COG5039	Polysaccharide pyruvyl transferase
ORP33_17020	COG1216	Glycosyl transferase, family 2
ORP33_17030	COG0438	transferase activity, transferring glycosyl groups
ORP33_17035	COG1215	transferase activity, transferring glycosyl groups
ORP33_17040	COG0438	transferase activity, transferring glycosyl groups
ORP33_17045	COG1086	Polysaccharide biosynthesis protein
ORP33_17050	COG0489	protein tyrosine kinase activity
ORP33_17055	COG3944	biosynthesis protein
ORP33_17060	COG1396	sequence-specific DNA binding
ORP33_17065	COG2272	Belongs to the type-B carboxylesterase lipase family
ORP33_17075	COG3479	Phenolic acid decarboxylase
ORP33_17085	COG1794	racemase activity, acting on amino acids and derivatives
ORP33_17090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ORP33_17095	COG1621	beta-fructofuranosidase activity
ORP33_17100	COG1621	beta-fructofuranosidase activity
ORP33_17105	COG0531	amino acid
ORP33_17110	COG1309	transcriptional regulator
ORP33_17115	COG2076	Multidrug Resistance protein
ORP33_17120	COG2076	Multidrug Resistance protein
ORP33_17130	COG0277	FAD linked oxidase domain protein
ORP33_17135	COG3621	Patatin-like phospholipase
ORP33_17145	COG0740	serine-type endopeptidase activity
ORP33_17150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ORP33_17155	COG0366	Alpha amylase catalytic
ORP33_17160	COG1554	hydrolase, family 65, central catalytic
ORP33_17165	COG5521	maltodextrose utilization protein MalA
ORP33_17170	COG3833	ABC-type maltose transport systems, permease component
ORP33_17175	COG1175	transmembrane transport
ORP33_17180	COG2182	Extracellular solute-binding protein
ORP33_17185	COG0366	Alpha amylase catalytic
ORP33_17190	COG1609	Transcriptional regulator
ORP33_17195	COG1611	Belongs to the LOG family
ORP33_17200	COG1694	Mazg nucleotide pyrophosphohydrolase
ORP33_17205	COG0659	secondary active sulfate transmembrane transporter activity
ORP33_17210	COG0288	reversible hydration of carbon dioxide
ORP33_17215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ORP33_17220	COG0577	efflux transmembrane transporter activity
ORP33_17225	COG1136	(ABC) transporter
ORP33_17230	COG5002	protein histidine kinase activity
ORP33_17235	COG0745	RESPONSE REGULATOR receiver
ORP33_17245	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ORP33_17250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ORP33_17255	COG1481	regulation of sporulation
ORP33_17260	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ORP33_17265	COG1660	Displays ATPase and GTPase activities
ORP33_17270	COG1051	belongs to the nudix hydrolase family
ORP33_17275	COG0492	ferredoxin-NADP+ reductase activity
ORP33_17280	COG3883	PFAM NLP P60 protein
ORP33_17280	COG0791	NLP P60 protein
ORP33_17285	COG0457	Tetratricopeptide repeat
ORP33_17290	COG1132	(ABC) transporter
ORP33_17310	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ORP33_17310	COG0140	phosphoribosyl-ATP diphosphatase activity
ORP33_17315	COG0107	imidazoleglycerol-phosphate synthase activity
ORP33_17320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ORP33_17325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ORP33_17330	COG0131	Imidazoleglycerol-phosphate dehydratase
ORP33_17335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ORP33_17340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ORP33_17345	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ORP33_17350	COG4990	cell redox homeostasis
ORP33_17355	COG5297	Belongs to the glycosyl hydrolase family 6
ORP33_17360	COG0110	maltose O-acetyltransferase activity
ORP33_17365	COG0546	phosphoglycolate phosphatase activity
ORP33_17370	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ORP33_17375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ORP33_17380	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ORP33_17385	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ORP33_17390	COG0363	glucosamine-6-phosphate deaminase activity
ORP33_17395	COG2188	Transcriptional regulator
ORP33_17400	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ORP33_17405	COG1846	Transcriptional regulator
ORP33_17410	COG2124	cytochrome p450
ORP33_17420	COG1846	Transcriptional regulator
ORP33_17425	COG2814	Major facilitator Superfamily
ORP33_17430	COG1950	PFAM Membrane protein of
ORP33_17435	COG1983	PspC domain protein
ORP33_17440	COG3595	metallopeptidase activity
ORP33_17455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ORP33_17460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ORP33_17465	COG0556	nucleotide-excision repair
ORP33_17470	COG4897	Protein conserved in bacteria
ORP33_17475	COG3848	Pyruvate phosphate dikinase
ORP33_17475	COG0574	Belongs to the PEP-utilizing enzyme family
ORP33_17480	COG1309	transcriptional regulator
ORP33_17485	COG2814	Major facilitator Superfamily
ORP33_17490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ORP33_17500	COG3409	Peptidoglycan-binding domain 1 protein
ORP33_17500	COG0793	Belongs to the peptidase S41A family
ORP33_17505	COG2177	Part of the ABC transporter FtsEX involved in
ORP33_17510	COG2884	Cell division ATP-binding protein ftsE
ORP33_17535	COG0494	nUDIX hydrolase
ORP33_17540	COG1011	Hydrolase
ORP33_17570	COG4555	ABC transporter
ORP33_17580	COG2010	Cytochrome c
ORP33_17585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ORP33_17595	COG0653	protein targeting
ORP33_17600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ORP33_17610	COG1516	flagellar protein fliS
ORP33_17615	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ORP33_17620	COG1334	flagellar protein FlaG
ORP33_17625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ORP33_17630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ORP33_17635	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ORP33_17645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ORP33_17650	COG4786	Flagellar basal body rod
ORP33_17650	COG1256	bacterial-type flagellum assembly
ORP33_17655	COG3418	PFAM FlgN family protein
ORP33_17660	COG2747	anti-sigma28 factor FlgM
ORP33_17670	COG1040	competence protein
ORP33_17680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ORP33_17685	COG1307	EDD domain protein, DegV family
ORP33_17690	COG2197	response regulator
ORP33_17695	COG4585	Histidine kinase
ORP33_17700	COG1739	Uncharacterized protein family UPF0029
ORP33_17705	COG1316	TRANSCRIPTIONal
ORP33_17710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ORP33_17715	COG0438	transferase activity, transferring glycosyl groups
ORP33_17720	COG1215	transferase activity, transferring glycosyl groups
ORP33_17725	COG3206	protein involved in exopolysaccharide biosynthesis
ORP33_17730	COG3307	-O-antigen
ORP33_17735	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ORP33_17740	COG0438	transferase activity, transferring glycosyl groups
ORP33_17740	COG0297	glycogen (starch) synthase activity
ORP33_17745	COG2244	polysaccharide biosynthetic process
ORP33_17755	COG0860	N-Acetylmuramoyl-L-alanine amidase
ORP33_17755	COG2247	cell wall binding repeat
ORP33_17760	COG2247	cell wall binding repeat
ORP33_17760	COG2385	sporulation resulting in formation of a cellular spore
ORP33_17770	COG1316	TRANSCRIPTIONal
ORP33_17775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ORP33_17780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ORP33_17795	COG1215	transferase activity, transferring glycosyl groups
ORP33_17795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ORP33_17800	COG0463	Glycosyl transferase, family 2
ORP33_17805	COG0463	Glycosyl transferase, family 2
ORP33_17825	COG1134	teichoic acid transport
ORP33_17830	COG1682	transport, permease protein
ORP33_17835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ORP33_17840	COG0438	transferase activity, transferring glycosyl groups
ORP33_17845	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ORP33_17850	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ORP33_17855	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ORP33_17865	COG4193	domain, Protein
ORP33_17870	COG1482	cell wall glycoprotein biosynthetic process
ORP33_17875	COG0697	spore germination
ORP33_17880	COG0814	amino acid
ORP33_17890	COG2814	Major facilitator Superfamily
ORP33_17895	COG1316	TRANSCRIPTIONal
ORP33_17900	COG0561	phosphatase activity
ORP33_17905	COG0791	NLP P60 protein
ORP33_17915	COG2843	Capsule synthesis protein
ORP33_17925	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ORP33_17930	COG1609	Transcriptional regulator
ORP33_17935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ORP33_17940	COG1869	D-ribose catabolic process
ORP33_17945	COG1129	ABC transporter
ORP33_17950	COG1172	Belongs to the binding-protein-dependent transport system permease family
ORP33_17955	COG1879	ABC-type sugar transport system periplasmic component
ORP33_17960	COG3103	Sh3 type 3 domain protein
ORP33_17970	COG2249	NAD(P)H dehydrogenase (quinone) activity
ORP33_17975	COG3527	Alpha-acetolactate decarboxylase
ORP33_17980	COG0028	Belongs to the TPP enzyme family
ORP33_17985	COG0583	DNA-binding transcription factor activity
ORP33_17990	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ORP33_18005	COG5337	Spore coat protein CotH
ORP33_18015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ORP33_18025	COG0405	Gamma-glutamyltransferase
ORP33_18030	COG1522	sequence-specific DNA binding
ORP33_18035	COG2059	Chromate
ORP33_18040	COG2059	Chromate
ORP33_18050	COG0655	NAD(P)H dehydrogenase (quinone) activity
ORP33_18055	COG0583	DNA-binding transcription factor activity
ORP33_18060	COG1515	deoxyribonuclease V activity
ORP33_18115	COG3878	Protein conserved in bacteria
ORP33_18120	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ORP33_18125	COG4464	protein tyrosine phosphatase activity
ORP33_18130	COG0489	protein tyrosine kinase activity
ORP33_18135	COG3944	biosynthesis protein
ORP33_18145	COG4715	Zinc finger, swim domain protein
ORP33_18150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ORP33_18155	COG0561	phosphatase activity
ORP33_18160	COG1349	DNA-binding transcription factor activity
ORP33_18165	COG0629	single-stranded DNA binding
ORP33_18180	COG3764	Sortase (surface protein transpeptidase)
ORP33_18185	COG0745	RESPONSE REGULATOR receiver
ORP33_18185	COG2972	Histidine kinase
ORP33_18190	COG1970	mechanosensitive ion channel activity
ORP33_18195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ORP33_18200	COG0457	Tetratricopeptide repeat
ORP33_18205	COG4786	Flagellar basal body rod
ORP33_18210	COG4786	Flagellar basal body rod
ORP33_18215	COG1077	Cell shape determining protein MreB Mrl
ORP33_18220	COG1609	Transcriptional regulator
ORP33_18225	COG1846	Transcriptional regulator
ORP33_18230	COG2814	Major facilitator Superfamily
ORP33_18235	COG3420	alginic acid biosynthetic process
ORP33_18240	COG1953	Uracil, thiamine, allantoin
ORP33_18245	COG0477	Major facilitator Superfamily
ORP33_18250	COG1335	isochorismatase
ORP33_18260	COG0004	ammonium transporteR
ORP33_18265	COG0347	Belongs to the P(II) protein family
ORP33_18270	COG0671	phosphoesterase, PA-phosphatase related
ORP33_18280	COG0739	heme binding
ORP33_18285	COG1247	-acetyltransferase
ORP33_18300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ORP33_18305	COG0789	Transcriptional regulator
ORP33_18315	COG2910	NAD(P)H-binding
ORP33_18320	COG1959	2 iron, 2 sulfur cluster binding
ORP33_18325	COG0804	urea catabolic process
ORP33_18330	COG0832	Belongs to the urease beta subunit family
ORP33_18335	COG0831	urea catabolic process
ORP33_18345	COG3237	CsbD-like
ORP33_18350	COG1994	Peptidase M50
ORP33_18355	COG0457	Tetratricopeptide repeat
ORP33_18360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ORP33_18365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ORP33_18375	COG2304	oxidoreductase activity
ORP33_18380	COG2304	oxidoreductase activity
ORP33_18385	COG2385	sporulation resulting in formation of a cellular spore
ORP33_18390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ORP33_18400	COG4836	Membrane
ORP33_18410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ORP33_18415	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ORP33_18420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ORP33_18425	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ORP33_18430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ORP33_18435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ORP33_18445	COG0356	it plays a direct role in the translocation of protons across the membrane
ORP33_18455	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ORP33_18460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ORP33_18465	COG4475	Protein of unknown function (DUF436)
ORP33_18470	COG0698	ribose 5-phosphate isomerase
ORP33_18475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ORP33_18480	COG1971	Probably functions as a manganese efflux pump
ORP33_18485	COG0009	L-threonylcarbamoyladenylate synthase
ORP33_18490	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ORP33_18510	COG2890	protein-(glutamine-N5) methyltransferase activity
ORP33_18515	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ORP33_18520	COG0346	lactoylglutathione lyase activity
ORP33_18525	COG0789	Transcriptional regulator
ORP33_18530	COG0679	Auxin Efflux Carrier
ORP33_18535	COG0281	malic enzyme
ORP33_18540	COG1435	thymidine kinase activity
ORP33_18550	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ORP33_18555	COG1494	fructose-1,6-bisphosphatase
ORP33_18560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ORP33_18565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ORP33_18570	COG0191	fructose-bisphosphate aldolase activity
ORP33_18575	COG2204	response regulator
ORP33_18580	COG4821	SIS domain
ORP33_18585	COG0504	CTP synthase activity
ORP33_18590	COG3343	RNA polymerase activity
ORP33_18595	COG1960	acyl-CoA dehydrogenase activity
ORP33_18600	COG2181	nitrate reductase activity
ORP33_18600	COG0247	lactate metabolic process
ORP33_18605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ORP33_18610	COG4294	response to UV
ORP33_18620	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ORP33_18625	COG1132	(ABC) transporter
ORP33_18630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ORP33_18635	COG2181	nitrate reductase activity
ORP33_18640	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ORP33_18645	COG1140	nitrate reductase beta subunit
ORP33_18650	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ORP33_18655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ORP33_18665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ORP33_18670	COG2223	nitrite transmembrane transporter activity
ORP33_18675	COG0018	arginyl-trna synthetase
ORP33_18680	COG4506	Protein conserved in bacteria
ORP33_18695	COG0535	radical SAM domain protein
ORP33_18705	COG1131	(ABC) transporter
ORP33_18710	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ORP33_18715	COG0612	Peptidase, M16
ORP33_18720	COG0612	Peptidase, M16
ORP33_18730	COG3391	amine dehydrogenase activity
ORP33_18735	COG3391	amine dehydrogenase activity
ORP33_18740	COG0457	Tetratricopeptide repeat
ORP33_18750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ORP33_18755	COG0010	Belongs to the arginase family
ORP33_18760	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ORP33_18765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ORP33_18775	COG1994	Peptidase M50
ORP33_18780	COG1942	4-Oxalocrotonate Tautomerase
ORP33_18785	COG1846	Transcriptional regulator
ORP33_18790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ORP33_18795	COG0477	Major facilitator Superfamily
ORP33_18800	COG1959	2 iron, 2 sulfur cluster binding
ORP33_18805	COG3465	dGTPase activity
ORP33_18810	COG1078	dGTPase activity
ORP33_18825	COG0697	spore germination
ORP33_18830	COG0095	Lipoate-protein ligase
ORP33_18835	COG0583	DNA-binding transcription factor activity
ORP33_18840	COG0280	phosphate acetyltransferase
ORP33_18845	COG3253	May function as heme-dependent peroxidase
ORP33_18850	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_18855	COG0436	Aminotransferase
ORP33_18860	COG2814	Major facilitator Superfamily
ORP33_18865	COG0151	Belongs to the GarS family
ORP33_18870	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_18875	COG1917	Cupin 2, conserved barrel domain protein
ORP33_18880	COG0077	Prephenate dehydratase
ORP33_18885	COG2814	Major facilitator Superfamily
ORP33_18890	COG0833	amino acid
ORP33_18895	COG4187	Peptidase family M20/M25/M40
ORP33_18900	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_18905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ORP33_18915	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ORP33_18920	COG1091	dTDP-4-dehydrorhamnose reductase activity
ORP33_18925	COG1088	dTDP-glucose 4,6-dehydratase activity
ORP33_18930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ORP33_18935	COG3980	spore coat polysaccharide biosynthesis protein
ORP33_18940	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
ORP33_18945	COG2089	acid synthase
ORP33_18950	COG0456	acetyltransferase
ORP33_18955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ORP33_18960	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ORP33_18965	COG0463	Glycosyl transferase, family 2
ORP33_18975	COG2363	Small membrane protein
ORP33_18980	COG2233	PERMEase
ORP33_18990	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_18995	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ORP33_19000	COG1216	Glycosyl transferase, family 2
ORP33_19015	COG1695	Transcriptional regulator
ORP33_19020	COG0351	phosphomethylpyrimidine kinase
ORP33_19030	COG1621	beta-fructofuranosidase activity
ORP33_19035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ORP33_19035	COG1263	PTS System
ORP33_19040	COG2116	formate transmembrane transporter activity
ORP33_19045	COG3711	transcriptional antiterminator
ORP33_19055	COG1404	Belongs to the peptidase S8 family
ORP33_19060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ORP33_19065	COG0778	Nitroreductase
ORP33_19070	COG0772	Belongs to the SEDS family
ORP33_19080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ORP33_19085	COG1845	cytochrome c oxidase, subunit III
ORP33_19090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ORP33_19100	COG2261	transglycosylase associated protein
ORP33_19105	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ORP33_19110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ORP33_19115	COG2246	polysaccharide biosynthetic process
ORP33_19120	COG1309	transcriptional regulator
ORP33_19130	COG3162	membrane
ORP33_19135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ORP33_19140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ORP33_19145	COG2837	iron assimilation
ORP33_19150	COG2822	iron ion transport
ORP33_19155	COG0672	)-iron permease
ORP33_19160	COG0352	thiamine-phosphate diphosphorylase activity
ORP33_19165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ORP33_19170	COG0583	DNA-binding transcription factor activity
ORP33_19175	COG1380	Effector of murein hydrolase LrgA
ORP33_19180	COG1346	cytolysis
ORP33_19185	COG2814	Major facilitator Superfamily
ORP33_19190	COG4895	conserved protein (DUF2196)
ORP33_19195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ORP33_19200	COG0346	lactoylglutathione lyase activity
ORP33_19210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ORP33_19215	COG1404	Belongs to the peptidase S8 family
ORP33_19220	COG1263	PTS System
ORP33_19220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ORP33_19225	COG3711	transcriptional antiterminator
ORP33_19230	COG1442	glycosyl transferase family 8
ORP33_19235	COG5522	Integral membrane protein (intg_mem_TP0381)
ORP33_19240	COG1846	Transcriptional regulator
ORP33_19245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ORP33_19250	COG2234	aminopeptidase activity
ORP33_19265	COG2814	Major facilitator Superfamily
ORP33_19270	COG2357	RelA SpoT domain protein
ORP33_19275	COG1575	Belongs to the MenA family. Type 1 subfamily
ORP33_19280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ORP33_19285	COG1696	Membrane protein involved in D-alanine export
ORP33_19290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ORP33_19295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ORP33_19300	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ORP33_19305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ORP33_19310	COG1486	melibiose metabolic process
ORP33_19315	COG1447	Phosphotransferase system cellobiose-specific component IIA
ORP33_19320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ORP33_19325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ORP33_19330	COG3711	transcriptional antiterminator
ORP33_19330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ORP33_19340	COG2094	Belongs to the DNA glycosylase MPG family
ORP33_19345	COG0753	catalase activity
ORP33_19350	COG2814	Major facilitator Superfamily
ORP33_19355	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ORP33_19360	COG1131	(ABC) transporter
ORP33_19380	COG1595	DNA-templated transcription, initiation
ORP33_19385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ORP33_19390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ORP33_19395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ORP33_19400	COG4988	ABC transporter
ORP33_19405	COG1294	oxidase, subunit
ORP33_19410	COG1271	oxidase subunit
ORP33_19415	COG3493	citrate carrier protein
ORP33_19420	COG0501	Belongs to the peptidase M48B family
ORP33_19430	COG0726	polysaccharide deacetylase
ORP33_19435	COG3842	ATPase activity
ORP33_19440	COG2508	Transcriptional regulator
ORP33_19445	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_19450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ORP33_19460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ORP33_19470	COG4585	Histidine kinase
ORP33_19475	COG2197	response regulator
ORP33_19480	COG2195	Cleaves the N-terminal amino acid of tripeptides
ORP33_19495	COG4894	glucomannan catabolic process
ORP33_19500	COG4894	glucomannan catabolic process
ORP33_19505	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ORP33_19510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ORP33_19515	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_19520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ORP33_19525	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ORP33_19530	COG2610	gluconate transmembrane transporter activity
ORP33_19535	COG0500	methyltransferase
ORP33_19540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ORP33_19555	COG0693	protein deglycase activity
ORP33_19555	COG0753	catalase activity
ORP33_19560	COG2851	Citrate transporter
ORP33_19565	COG2273	Hydrolase Family 16
ORP33_19570	COG3711	transcriptional antiterminator
ORP33_19580	COG2270	Major facilitator Superfamily
ORP33_19585	COG0513	Belongs to the DEAD box helicase family
ORP33_19590	COG3401	FG-GAP repeat protein
ORP33_19590	COG2755	lipolytic protein G-D-S-L family
ORP33_19635	COG0697	spore germination
ORP33_19650	COG0589	response to stress
ORP33_19655	COG2723	6-phospho-beta-galactosidase activity
ORP33_19660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ORP33_19660	COG2190	(PTS) system
ORP33_19660	COG1263	PTS System
ORP33_19690	COG3507	Belongs to the glycosyl hydrolase 43 family
ORP33_19705	COG2986	histidine ammonia-lyase
ORP33_19710	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ORP33_19715	COG1228	amidohydrolase
ORP33_19720	COG0010	Belongs to the arginase family
ORP33_19725	COG0833	amino acid
ORP33_19730	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ORP33_19735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ORP33_19740	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ORP33_19745	COG2390	Transcriptional regulator
ORP33_19755	COG3192	ethanolamine utilization protein
ORP33_19760	COG2079	MmgE PrpD family protein
ORP33_19765	COG1473	amidohydrolase
ORP33_19770	COG1126	abc transporter atp-binding protein
ORP33_19775	COG0765	amino acid transport
ORP33_19780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ORP33_19785	COG0456	acetyltransferase
ORP33_19790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ORP33_19800	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ORP33_19805	COG0561	phosphatase activity
ORP33_19835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ORP33_19840	COG5294	Protein conserved in bacteria
ORP33_19845	COG0577	efflux transmembrane transporter activity
ORP33_19850	COG1136	(ABC) transporter
ORP33_19855	COG2205	protein histidine kinase activity
ORP33_19860	COG0745	RESPONSE REGULATOR receiver
ORP33_19865	COG0191	fructose-bisphosphate aldolase activity
ORP33_19870	COG1082	Xylose isomerase domain protein TIM barrel
ORP33_19875	COG1082	Xylose isomerase domain protein TIM barrel
ORP33_19880	COG0673	inositol 2-dehydrogenase activity
ORP33_19885	COG2814	Major facilitator Superfamily
ORP33_19890	COG1082	Xylose isomerase domain protein TIM barrel
ORP33_19895	COG3962	Belongs to the TPP enzyme family
ORP33_19900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ORP33_19905	COG3718	enzyme involved in inositol metabolism
ORP33_19910	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_19915	COG1349	DNA-binding transcription factor activity
ORP33_19920	COG0667	Aldo Keto reductase
ORP33_19935	COG2814	Major facilitator Superfamily
ORP33_19940	COG0326	Molecular chaperone. Has ATPase activity
ORP33_19950	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_19955	COG1309	transcriptional regulator
ORP33_19960	COG1012	belongs to the aldehyde dehydrogenase family
ORP33_19965	COG1714	RDD family
ORP33_19970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ORP33_19980	COG1714	RDD family
ORP33_19985	COG2311	Membrane
ORP33_19990	COG1917	Cupin 2, conserved barrel domain protein
ORP33_19995	COG1309	transcriptional regulator
ORP33_20000	COG1028	Short-chain dehydrogenase reductase Sdr
ORP33_20005	COG1846	Transcriptional regulator
ORP33_20010	COG1380	Effector of murein hydrolase LrgA
ORP33_20015	COG1346	cytolysis
ORP33_20020	COG5039	Polysaccharide pyruvyl transferase
ORP33_20025	COG1929	Belongs to the glycerate kinase type-1 family
ORP33_20030	COG1802	Transcriptional regulator
ORP33_20035	COG1070	Carbohydrate kinase
ORP33_20040	COG2610	gluconate transmembrane transporter activity
ORP33_20045	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ORP33_20050	COG0450	alkyl hydroperoxide reductase
ORP33_20055	COG3634	alkyl hydroperoxide reductase activity
ORP33_20060	COG2723	6-phospho-beta-galactosidase activity
ORP33_20065	COG2190	(PTS) system
ORP33_20070	COG2188	Transcriptional regulator
ORP33_20080	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ORP33_20115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ORP33_20130	COG1063	alcohol dehydrogenase
ORP33_20150	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ORP33_20155	COG0456	acetyltransferase
ORP33_20160	COG0457	Tetratricopeptide repeat
ORP33_20170	COG0010	Belongs to the arginase family
ORP33_20175	COG0833	amino acid
ORP33_20180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ORP33_20185	COG3829	transcription factor binding
ORP33_20190	COG5002	protein histidine kinase activity
ORP33_20195	COG0745	RESPONSE REGULATOR receiver
ORP33_20210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ORP33_20215	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ORP33_20220	COG4853	Protein conserved in bacteria
ORP33_20225	COG4863	YycH protein
ORP33_20230	COG5002	protein histidine kinase activity
ORP33_20235	COG0745	RESPONSE REGULATOR receiver
ORP33_20265	COG0346	lactoylglutathione lyase activity
ORP33_20270	COG0305	Participates in initiation and elongation during chromosome replication
ORP33_20285	COG3093	addiction module antidote protein HigA
ORP33_20290	COG2807	transmembrane transport
ORP33_20295	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ORP33_20300	COG0359	binds to the 23S rRNA
ORP33_20305	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ORP33_20310	COG4241	membrane
ORP33_20320	COG5577	PFAM Coat F domain
ORP33_20325	COG1733	regulation of RNA biosynthetic process
ORP33_20330	COG1227	inorganic diphosphatase activity
ORP33_20340	COG2271	Major facilitator Superfamily
ORP33_20345	COG4978	Transcriptional regulator
ORP33_20345	COG0789	Transcriptional regulator
ORP33_20355	COG4319	ketosteroid isomerase
ORP33_20360	COG1357	PFAM Pentapeptide repeats (8 copies)
ORP33_20365	COG2814	Major facilitator Superfamily
ORP33_20370	COG0583	DNA-binding transcription factor activity
ORP33_20375	COG2153	protein acetylation
ORP33_20385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ORP33_20390	COG1846	Transcriptional regulator
ORP33_20395	COG2153	protein acetylation
ORP33_20400	COG2364	Membrane
ORP33_20405	COG0456	acetyltransferase
ORP33_20410	COG2315	Protein conserved in bacteria
ORP33_20415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ORP33_20420	COG2814	Major facilitator Superfamily
ORP33_20425	COG1331	Highly conserved protein containing a thioredoxin domain
ORP33_20430	COG0789	Transcriptional regulator
ORP33_20435	COG0697	spore germination
ORP33_20440	COG1331	Highly conserved protein containing a thioredoxin domain
ORP33_20445	COG1266	CAAX protease self-immunity
ORP33_20450	COG2814	Major facilitator Superfamily
ORP33_20450	COG0477	Major facilitator Superfamily
ORP33_20455	COG0110	maltose O-acetyltransferase activity
ORP33_20460	COG0346	lactoylglutathione lyase activity
ORP33_20465	COG1609	Transcriptional regulator
ORP33_20470	COG0708	Exodeoxyribonuclease III
ORP33_20475	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ORP33_20480	COG0629	single-stranded DNA binding
ORP33_20485	COG0360	Binds together with S18 to 16S ribosomal RNA
ORP33_20490	COG0012	GTP binding
ORP33_20495	COG0243	molybdopterin cofactor binding
ORP33_20500	COG4481	Protein conserved in bacteria
ORP33_20505	COG3949	Membrane
ORP33_20515	COG1475	DNA binding
ORP33_20520	COG1192	Involved in chromosome partitioning
ORP33_20530	COG1475	DNA binding
ORP33_20535	COG0357	Ribosomal RNA small subunit methyltransferase G
ORP33_20540	COG0445	tRNA wobble uridine modification
ORP33_20545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ORP33_20550	COG1847	R3H domain protein
ORP33_20555	COG0706	membrane insertase activity
ORP33_20560	COG0594	ribonuclease P activity