locus-tag	class	description
O7A_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
O7A_00010	COG0592	DNA-directed DNA polymerase activity
O7A_00015	COG2501	S4 domain
O7A_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
O7A_00030	COG0187	DNA topoisomerase II activity
O7A_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
O7A_00070	COG0517	IMP dehydrogenase activity
O7A_00070	COG0516	GMP reductase activity
O7A_00075	COG1686	Belongs to the peptidase S11 family
O7A_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
O7A_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
O7A_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
O7A_00100	COG1428	Deoxynucleoside kinase
O7A_00105	COG1428	Deoxynucleoside kinase
O7A_00110	COG1388	LysM domain
O7A_00110	COG3858	chitin binding
O7A_00115	COG1335	isochorismatase
O7A_00120	COG0590	tRNA wobble adenosine to inosine editing
O7A_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
O7A_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
O7A_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
O7A_00180	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
O7A_00185	COG3853	Toxic anion resistance protein (TelA)
O7A_00190	COG1982	Orn Lys Arg decarboxylase major
O7A_00195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
O7A_00200	COG3870	Protein conserved in bacteria
O7A_00205	COG1728	Protein conserved in bacteria
O7A_00210	COG0470	DNA polymerase III
O7A_00215	COG1774	PSP1 C-terminal conserved region
O7A_00220	COG4467	Involved in initiation control of chromosome replication
O7A_00225	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
O7A_00230	COG2827	Endonuclease containing a URI domain
O7A_00235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
O7A_00240	COG2002	toxin-antitoxin pair type II binding
O7A_00245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O7A_00245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O7A_00250	COG0084	hydrolase, TatD family'
O7A_00255	COG3583	domain protein
O7A_00255	COG3584	3D domain protein
O7A_00260	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
O7A_00265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
O7A_00275	COG4466	Protein conserved in bacteria
O7A_00285	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
O7A_00290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
O7A_00295	COG0251	oxidation-reduction process
O7A_00300	COG2088	sporulation resulting in formation of a cellular spore
O7A_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
O7A_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
O7A_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
O7A_00325	COG0193	aminoacyl-tRNA hydrolase activity
O7A_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
O7A_00340	COG2002	toxin-antitoxin pair type II binding
O7A_00345	COG2244	polysaccharide biosynthetic process
O7A_00350	COG3956	TIGRFAM MazG family protein
O7A_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
O7A_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
O7A_00375	COG1098	S1 RNA binding domain
O7A_00390	COG2208	phosphoserine phosphatase activity
O7A_00395	COG2304	oxidoreductase activity
O7A_00400	COG0515	serine threonine protein kinase
O7A_00405	COG0037	tRNA processing
O7A_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
O7A_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
O7A_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
O7A_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
O7A_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O7A_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
O7A_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
O7A_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O7A_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
O7A_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
O7A_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
O7A_00470	COG1396	sequence-specific DNA binding
O7A_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
O7A_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
O7A_00565	COG4463	regulation of RNA biosynthetic process
O7A_00570	COG3880	PFAM UvrB UvrC protein
O7A_00575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
O7A_00580	COG0542	response to heat
O7A_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
O7A_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
O7A_00595	COG4956	integral membrane protein (PIN domain superfamily)
O7A_00600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
O7A_00605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
O7A_00610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
O7A_00620	COG1045	serine acetyltransferase
O7A_00625	COG0215	cysteine-tRNA ligase activity
O7A_00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
O7A_00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
O7A_00640	COG3688	RNA-binding protein containing a PIN domain
O7A_00645	COG1595	DNA-templated transcription, initiation
O7A_00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
O7A_00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
O7A_00660	COG0250	Participates in transcription elongation, termination and antitermination
O7A_00665	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
O7A_00670	COG0081	regulation of translation
O7A_00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
O7A_00680	COG0222	ribosome binding
O7A_00685	COG2813	Specifically methylates the guanine in position
O7A_00690	COG0085	RNA polymerase activity
O7A_00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
O7A_00700	COG1358	cellular component organization or biogenesis
O7A_00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
O7A_00710	COG0049	tRNA binding
O7A_00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
O7A_00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
O7A_00725	COG0596	Alpha beta hydrolase
O7A_00730	COG0051	transcription antitermination factor activity, RNA binding
O7A_00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
O7A_00740	COG0088	Forms part of the polypeptide exit tunnel
O7A_00745	COG0089	rRNA binding
O7A_00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
O7A_00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
O7A_00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
O7A_00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
O7A_00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
O7A_00775	COG0255	Belongs to the universal ribosomal protein uL29 family
O7A_00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
O7A_00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
O7A_00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
O7A_00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
O7A_00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
O7A_00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
O7A_00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
O7A_00825	COG1841	ribosomal large subunit assembly
O7A_00830	COG0200	Binds to the 23S rRNA
O7A_00835	COG0201	protein transport
O7A_00840	COG0563	adenylate kinase activity
O7A_00845	COG0024	Methionine aminopeptidase
O7A_00850	COG2163	COG2163 Ribosomal protein L14E L6E L27E
O7A_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
O7A_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
O7A_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
O7A_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
O7A_00875	COG0202	RNA polymerase activity
O7A_00880	COG0203	ribosomal protein L17
O7A_00885	COG1122	ATPase activity
O7A_00890	COG1122	ATPase activity
O7A_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
O7A_00900	COG0101	tRNA pseudouridine synthase activity
O7A_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
O7A_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
O7A_00915	COG2226	methyltransferase
O7A_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7A_00930	COG0489	protein tyrosine kinase activity
O7A_00940	COG2194	sulfuric ester hydrolase activity
O7A_00945	COG0726	polysaccharide deacetylase
O7A_01030	COG0659	secondary active sulfate transmembrane transporter activity
O7A_01035	COG0385	Bile acid
O7A_01040	COG2819	hydrolase of the alpha beta superfamily
O7A_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7A_01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7A_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7A_01060	COG2207	Transcriptional regulator
O7A_01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7A_01065	COG3876	Protein conserved in bacteria
O7A_01070	COG1472	Belongs to the glycosyl hydrolase 3 family
O7A_01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O7A_01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7A_01080	COG1263	PTS System
O7A_01085	COG1737	Transcriptional regulator
O7A_01090	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
O7A_01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7A_01100	COG1683	Conserved Protein
O7A_01130	COG1595	DNA-templated transcription, initiation
O7A_01135	COG5662	AntiSigma factor
O7A_01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
O7A_01145	COG4856	YbbR-like protein
O7A_01150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
O7A_01155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
O7A_01160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
O7A_01165	COG2169	Transcriptional regulator
O7A_01170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
O7A_01175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
O7A_01180	COG3002	Belongs to the UPF0753 family
O7A_01185	COG0288	reversible hydration of carbon dioxide
O7A_01195	COG5609	conserved protein (DUF2294)
O7A_01205	COG0640	Transcriptional regulator
O7A_01210	COG2814	Major facilitator Superfamily
O7A_01215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
O7A_01225	COG0535	radical SAM domain protein
O7A_01230	COG1266	CAAX protease self-immunity
O7A_01235	COG1131	(ABC) transporter
O7A_01245	COG1413	lyase activity
O7A_01250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_01255	COG0596	Alpha beta hydrolase
O7A_01260	COG0745	RESPONSE REGULATOR receiver
O7A_01265	COG0642	Histidine kinase
O7A_01275	COG0515	serine threonine protein kinase
O7A_01290	COG1113	amino acid transport
O7A_01305	COG2602	Beta-lactamase
O7A_01310	COG2124	cytochrome p450
O7A_01320	COG0531	amino acid
O7A_01325	COG0584	glycerophosphoryl diester phosphodiesterase
O7A_01330	COG2271	Major facilitator Superfamily
O7A_01340	COG1846	Transcriptional regulator
O7A_01340	COG0456	acetyltransferase
O7A_01345	COG2271	Major facilitator Superfamily
O7A_01360	COG3409	Peptidoglycan-binding domain 1 protein
O7A_01365	COG0697	spore germination
O7A_01370	COG2207	Transcriptional regulator
O7A_01370	COG1917	Cupin 2, conserved barrel domain protein
O7A_01375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
O7A_01380	COG3591	Belongs to the peptidase S1B family
O7A_01390	COG0596	Alpha beta hydrolase
O7A_01395	COG1183	phosphatidylcholine synthase activity
O7A_01400	COG0586	Pfam SNARE associated Golgi protein
O7A_01405	COG0688	phosphatidylethanolamine metabolic process
O7A_01415	COG2312	Erythromycin esterase
O7A_01420	COG2207	Transcriptional regulator
O7A_01430	COG1301	dicarboxylic acid transport
O7A_01435	COG2190	(PTS) system
O7A_01435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7A_01435	COG1263	PTS System
O7A_01440	COG0363	glucosamine-6-phosphate deaminase activity
O7A_01455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O7A_01460	COG0833	amino acid
O7A_01465	COG2040	homocysteine
O7A_01475	COG1115	amino acid carrier protein
O7A_01480	COG2066	Belongs to the glutaminase family
O7A_01485	COG4191	Histidine kinase
O7A_01490	COG0784	Response regulator, receiver
O7A_01495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
O7A_01500	COG1012	belongs to the aldehyde dehydrogenase family
O7A_01505	COG2271	Major facilitator Superfamily
O7A_01510	COG4948	Mandelate Racemase Muconate Lactonizing
O7A_01515	COG2186	Transcriptional regulator
O7A_01520	COG2721	sulfolactate sulfo-lyase activity
O7A_01525	COG3173	Aminoglycoside phosphotransferase
O7A_01535	COG0697	spore germination
O7A_01540	COG0745	RESPONSE REGULATOR receiver
O7A_01545	COG2205	protein histidine kinase activity
O7A_01550	COG1131	(ABC) transporter
O7A_01570	COG3773	Cell wall hydrolase
O7A_01575	COG2304	oxidoreductase activity
O7A_01585	COG3540	Alkaline phosphatase
O7A_01590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
O7A_01595	COG0805	protein transport
O7A_01600	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
O7A_01605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
O7A_01610	COG0477	Major facilitator Superfamily
O7A_01615	COG1309	transcriptional regulator
O7A_01620	COG0252	asparaginase activity
O7A_01625	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
O7A_01630	COG1714	RDD family
O7A_01635	COG1405	negative regulation of cell septum assembly
O7A_01635	COG3012	SEC-C Motif Domain Protein
O7A_01640	COG3290	protein histidine kinase activity
O7A_01645	COG3279	Response regulator of the LytR AlgR family
O7A_01650	COG4555	ABC transporter
O7A_01655	COG1668	transmembrane transport
O7A_01660	COG0667	Aldo Keto reductase
O7A_01670	COG1595	DNA-templated transcription, initiation
O7A_01675	COG1595	DNA-templated transcription, initiation
O7A_01680	COG1876	peptidase activity
O7A_01685	COG0457	Tetratricopeptide repeat
O7A_01690	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_01695	COG0366	Alpha amylase catalytic
O7A_01700	COG0803	Belongs to the bacterial solute-binding protein 9 family
O7A_01705	COG1121	(ABC) transporter
O7A_01710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
O7A_01715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7A_01720	COG2310	stress, protein
O7A_01725	COG2310	stress, protein
O7A_01730	COG2310	stress, protein
O7A_01735	COG0861	Integral membrane protein TerC family
O7A_01745	COG3853	Toxic anion resistance protein (TelA)
O7A_01750	COG0477	Major facilitator Superfamily
O7A_01755	COG2814	Major facilitator Superfamily
O7A_01760	COG0640	Transcriptional regulator
O7A_01765	COG4175	Glycine betaine
O7A_01765	COG0517	IMP dehydrogenase activity
O7A_01770	COG4176	ABC-type proline glycine betaine transport system permease component
O7A_01775	COG2113	Glycine betaine
O7A_01780	COG1473	amidohydrolase
O7A_01785	COG1288	antiporter activity
O7A_01800	COG0366	Alpha amylase catalytic
O7A_01805	COG0039	L-malate dehydrogenase activity
O7A_01810	COG1620	l-lactate permease
O7A_01815	COG2814	Major facilitator Superfamily
O7A_01820	COG1846	Transcriptional regulator
O7A_01825	COG1280	lysine exporter protein (LysE YggA)
O7A_01830	COG3403	YqcI/YcgG family
O7A_01835	COG1113	amino acid transport
O7A_01840	COG3665	Urea carboxylase-associated protein
O7A_01845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
O7A_01850	COG1660	Displays ATPase and GTPase activities
O7A_01855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
O7A_01860	COG2226	methyltransferase
O7A_01865	COG0583	DNA-binding transcription factor activity
O7A_01870	COG3458	cephalosporin-C deacetylase activity
O7A_01875	COG3541	Predicted nucleotidyltransferase
O7A_01880	COG0506	proline dehydrogenase activity
O7A_01885	COG1012	belongs to the aldehyde dehydrogenase family
O7A_01895	COG2508	Transcriptional regulator
O7A_01900	COG3689	TIGRFAM TIGR03943 family protein
O7A_01905	COG0701	Predicted permease
O7A_01910	COG2267	carboxylic ester hydrolase activity
O7A_01915	COG0492	ferredoxin-NADP+ reductase activity
O7A_01920	COG1587	Uroporphyrinogen-III synthase
O7A_01920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
O7A_01925	COG2146	nitrite reductase [NAD(P)H] activity
O7A_01930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
O7A_01935	COG0243	molybdopterin cofactor binding
O7A_01940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
O7A_01945	COG2223	nitrite transmembrane transporter activity
O7A_01950	COG1469	GTP cyclohydrolase I activity
O7A_01955	COG1376	ErfK ybiS ycfS ynhG family protein
O7A_01965	COG0523	cobalamin synthesis protein
O7A_01970	COG0765	amino acid transport
O7A_01975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7A_01985	COG1714	RDD family
O7A_01995	COG2723	6-phospho-beta-galactosidase activity
O7A_02005	COG3209	COG3209 Rhs family protein
O7A_02010	COG0840	transmembrane signaling receptor activity
O7A_02010	COG3290	protein histidine kinase activity
O7A_02015	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
O7A_02020	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
O7A_02025	COG1733	regulation of RNA biosynthetic process
O7A_02035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_02040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_02045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_02050	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
O7A_02055	COG2814	Major facilitator Superfamily
O7A_02065	COG0697	spore germination
O7A_02070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7A_02080	COG2364	Membrane
O7A_02085	COG1126	abc transporter atp-binding protein
O7A_02090	COG0765	amino acid transport
O7A_02095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7A_02100	COG0583	DNA-binding transcription factor activity
O7A_02105	COG0163	prenyltransferase activity
O7A_02110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
O7A_02125	COG0596	Alpha beta hydrolase
O7A_02130	COG3104	oligopeptide transport
O7A_02135	COG5434	Belongs to the glycosyl hydrolase 28 family
O7A_02145	COG0697	spore germination
O7A_02155	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
O7A_02160	COG1136	(ABC) transporter
O7A_02165	COG0577	efflux transmembrane transporter activity
O7A_02170	COG0745	RESPONSE REGULATOR receiver
O7A_02175	COG3850	Histidine kinase
O7A_02175	COG5002	protein histidine kinase activity
O7A_02180	COG0457	Tetratricopeptide repeat
O7A_02200	COG0527	aspartate kinase activity
O7A_02205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7A_02210	COG4605	iron ion homeostasis
O7A_02215	COG4604	ABC transporter, ATP-binding protein
O7A_02220	COG4607	ABC-type enterochelin transport system periplasmic component
O7A_02225	COG2814	Major facilitator Superfamily
O7A_02230	COG1309	transcriptional regulator
O7A_02235	COG0778	Nitroreductase
O7A_02240	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
O7A_02245	COG0640	Transcriptional regulator
O7A_02250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7A_02255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
O7A_02260	COG1012	belongs to the aldehyde dehydrogenase family
O7A_02265	COG4975	Glucose uptake
O7A_02270	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_02275	COG4549	nuclear export factor GLE1
O7A_02280	COG2372	response to copper ion
O7A_02280	COG1276	copper resistance
O7A_02285	COG1349	DNA-binding transcription factor activity
O7A_02295	COG2213	PTS system mannitol-specific
O7A_02300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7A_02305	COG0246	Mannitol dehydrogenase
O7A_02310	COG0473	3-isopropylmalate dehydrogenase activity
O7A_02315	COG0681	Belongs to the peptidase S26 family
O7A_02325	COG0412	Dienelactone hydrolase
O7A_02330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
O7A_02340	COG0561	phosphatase activity
O7A_02345	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
O7A_02350	COG1914	H( )-stimulated, divalent metal cation uptake system
O7A_02355	COG4336	lyase activity
O7A_02360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
O7A_02365	COG1984	allophanate hydrolase subunit 2
O7A_02370	COG1414	Transcriptional regulator
O7A_02375	COG2755	lipolytic protein G-D-S-L family
O7A_02385	COG2329	Antibiotic biosynthesis monooxygenase
O7A_02390	COG0768	penicillin binding
O7A_02395	COG4989	oxidoreductase activity
O7A_02400	COG3711	transcriptional antiterminator
O7A_02405	COG0318	PFAM AMP-dependent synthetase and ligase
O7A_02410	COG2226	methyltransferase
O7A_02415	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_02420	COG1917	Cupin 2, conserved barrel domain protein
O7A_02425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7A_02430	COG3871	stress protein (general stress protein 26)
O7A_02440	COG2814	Major facilitator Superfamily
O7A_02445	COG1522	sequence-specific DNA binding
O7A_02450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
O7A_02450	COG0551	DNA topoisomerase type I activity
O7A_02455	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
O7A_02460	COG3706	GGDEF domain
O7A_02465	COG5298	Protein conserved in bacteria
O7A_02470	COG1215	transferase activity, transferring glycosyl groups
O7A_02480	COG0531	amino acid
O7A_02485	COG0494	nUDIX hydrolase
O7A_02490	COG0028	Belongs to the TPP enzyme family
O7A_02505	COG1914	H( )-stimulated, divalent metal cation uptake system
O7A_02510	COG2261	transglycosylase associated protein
O7A_02515	COG4876	unkown
O7A_02520	COG2217	Heavy metal translocating P-type atpase
O7A_02525	COG3729	General stress protein
O7A_02530	COG0662	Cupin 2, conserved barrel domain protein
O7A_02535	COG2329	Antibiotic biosynthesis monooxygenase
O7A_02540	COG3546	catalase activity
O7A_02545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
O7A_02550	COG3290	protein histidine kinase activity
O7A_02555	COG4565	transcriptional regulatory protein
O7A_02560	COG1301	dicarboxylic acid transport
O7A_02565	COG0628	permease
O7A_02575	COG1131	(ABC) transporter
O7A_02580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
O7A_02590	COG1960	acyl-CoA dehydrogenase activity
O7A_02605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O7A_02610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_02615	COG1181	Belongs to the D-alanine--D-alanine ligase family
O7A_02620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
O7A_02625	COG0513	Belongs to the DEAD box helicase family
O7A_02630	COG3402	PFAM membrane-flanked domain
O7A_02635	COG3428	Bacterial PH domain
O7A_02640	COG0705	Rhomboid family
O7A_02645	COG0736	holo-[acyl-carrier-protein] synthase activity
O7A_02650	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
O7A_02655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O7A_02660	COG0864	Transcriptional regulator
O7A_02665	COG2337	Toxic component of a toxin-antitoxin (TA) module
O7A_02670	COG1366	Belongs to the anti-sigma-factor antagonist family
O7A_02675	COG1366	Belongs to the anti-sigma-factor antagonist family
O7A_02680	COG2172	sigma factor antagonist activity
O7A_02685	COG2208	phosphoserine phosphatase activity
O7A_02690	COG1366	Belongs to the anti-sigma-factor antagonist family
O7A_02695	COG2172	sigma factor antagonist activity
O7A_02700	COG1191	sigma factor activity
O7A_02705	COG2208	phosphoserine phosphatase activity
O7A_02720	COG1673	EVE domain
O7A_02725	COG1846	Transcriptional regulator
O7A_02730	COG2183	response to ionizing radiation
O7A_02740	COG3091	SprT-like family
O7A_02780	COG0582	viral genome integration into host DNA
O7A_02785	COG2856	Zn peptidase
O7A_02790	COG1396	sequence-specific DNA binding
O7A_02815	COG1674	ftsk spoiiie
O7A_02820	COG2946	Replication initiation factor
O7A_02855	COG0433	COG0433 Predicted ATPase
O7A_02865	COG5644	endopeptidase inhibitor activity
O7A_02870	COG0741	lytic transglycosylase activity
O7A_02870	COG0791	NLP P60 protein
O7A_02890	COG0457	Tetratricopeptide repeat
O7A_02900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7A_02905	COG1522	sequence-specific DNA binding
O7A_02910	COG1522	sequence-specific DNA binding
O7A_02915	COG1335	isochorismatase
O7A_02920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
O7A_02925	COG2814	Major facilitator Superfamily
O7A_02945	COG0693	protein deglycase activity
O7A_02950	COG1278	Cold shock
O7A_02955	COG1329	Transcriptional regulator
O7A_02960	COG0697	spore germination
O7A_02965	COG1917	Cupin 2, conserved barrel domain protein
O7A_02965	COG2207	Transcriptional regulator
O7A_02970	COG0697	spore germination
O7A_02975	COG3708	Transcriptional regulator
O7A_02975	COG2207	Transcriptional regulator
O7A_02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7A_02985	COG0477	Major facilitator Superfamily
O7A_02995	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
O7A_03005	COG0697	spore germination
O7A_03010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7A_03015	COG2030	dehydratase
O7A_03020	COG3545	Serine hydrolase
O7A_03025	COG1733	regulation of RNA biosynthetic process
O7A_03030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7A_03035	COG1733	regulation of RNA biosynthetic process
O7A_03040	COG2249	NAD(P)H dehydrogenase (quinone) activity
O7A_03045	COG2814	Major facilitator Superfamily
O7A_03050	COG1309	transcriptional regulator
O7A_03060	COG0640	Transcriptional regulator
O7A_03065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
O7A_03075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7A_03080	COG0697	spore germination
O7A_03085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7A_03090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
O7A_03095	COG0640	Transcriptional regulator
O7A_03100	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
O7A_03115	COG4585	Histidine kinase
O7A_03120	COG2197	response regulator
O7A_03125	COG2409	Drug exporters of the RND superfamily
O7A_03130	COG0596	Alpha beta hydrolase
O7A_03135	COG1811	Na channel or pump
O7A_03140	COG0789	Transcriptional regulator
O7A_03140	COG4978	Transcriptional regulator
O7A_03145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O7A_03150	COG0778	Nitroreductase
O7A_03155	COG0346	lactoylglutathione lyase activity
O7A_03160	COG2259	Doxx family
O7A_03165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_03185	COG2323	membrane
O7A_03190	COG2323	membrane
O7A_03195	COG0071	Belongs to the small heat shock protein (HSP20) family
O7A_03210	COG1309	transcriptional regulator
O7A_03220	COG0456	acetyltransferase
O7A_03230	COG1113	amino acid transport
O7A_03235	COG2318	DinB family
O7A_03240	COG1846	Transcriptional regulator
O7A_03245	COG1033	growth of symbiont in host cell
O7A_03245	COG2409	Drug exporters of the RND superfamily
O7A_03250	COG0778	Nitroreductase
O7A_03255	COG1846	Transcriptional regulator
O7A_03260	COG2814	Major facilitator Superfamily
O7A_03265	COG0730	response to heat
O7A_03270	COG1802	Transcriptional regulator
O7A_03275	COG3858	chitin binding
O7A_03275	COG1388	LysM domain
O7A_03280	COG1819	glycosyl
O7A_03290	COG1785	Belongs to the alkaline phosphatase family
O7A_03295	COG5646	InterPro IPR014922
O7A_03305	COG0454	-acetyltransferase
O7A_03310	COG1078	dGTPase activity
O7A_03315	COG1388	LysM domain
O7A_03320	COG2814	Major facilitator Superfamily
O7A_03325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7A_03330	COG1447	Phosphotransferase system cellobiose-specific component IIA
O7A_03335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7A_03340	COG2723	6-phospho-beta-galactosidase activity
O7A_03345	COG2188	Transcriptional regulator
O7A_03350	COG1940	carbohydrate kinase activity
O7A_03355	COG1482	cell wall glycoprotein biosynthetic process
O7A_03360	COG4124	Belongs to the glycosyl hydrolase 26 family
O7A_03405	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
O7A_03410	COG0802	atpase or kinase
O7A_03415	COG1214	PFAM Peptidase M22, glycoprotease
O7A_03420	COG0456	acetyltransferase
O7A_03425	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
O7A_03430	COG0488	(ABC) transporter
O7A_03435	COG0315	cyclic pyranopterin monophosphate synthase activity
O7A_03440	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
O7A_03445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
O7A_03450	COG0805	protein transport
O7A_03460	COG1266	CAAX protease self-immunity
O7A_03465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
O7A_03470	COG0459	protein refolding
O7A_03485	COG3378	Phage plasmid primase P4 family
O7A_03500	COG0270	DNA (cytosine-5-)-methyltransferase activity
O7A_03505	COG0270	DNA (cytosine-5-)-methyltransferase activity
O7A_03510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
O7A_03530	COG1401	restriction endodeoxyribonuclease activity
O7A_03550	COG0457	Tetratricopeptide repeat
O7A_03555	COG1063	alcohol dehydrogenase
O7A_03560	COG2211	Major facilitator Superfamily
O7A_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O7A_03570	COG1842	Phage shock protein A
O7A_03575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
O7A_03580	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
O7A_03585	COG4260	virion core protein, lumpy skin disease virus
O7A_03595	COG2814	Major facilitator Superfamily
O7A_03600	COG1063	alcohol dehydrogenase
O7A_03605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
O7A_03610	COG0823	Involved in the tonB-independent uptake of proteins
O7A_03625	COG2267	carboxylic ester hydrolase activity
O7A_03635	COG2132	Multicopper oxidase
O7A_03640	COG1113	amino acid transport
O7A_03650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O7A_03655	COG0714	Associated with various cellular activities
O7A_03660	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
O7A_03665	COG1305	Transglutaminase-like
O7A_03670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
O7A_03670	COG0519	Catalyzes the synthesis of GMP from XMP
O7A_03675	COG2252	PERMEase
O7A_03680	COG3064	Membrane
O7A_03690	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
O7A_03700	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
O7A_03705	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
O7A_03710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
O7A_03715	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
O7A_03720	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
O7A_03725	COG0047	phosphoribosylformylglycinamidine synthase activity
O7A_03730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
O7A_03735	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
O7A_03740	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
O7A_03745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
O7A_03750	COG0138	bifunctional purine biosynthesis protein purh
O7A_03755	COG0151	Belongs to the GarS family
O7A_03760	COG1522	sequence-specific DNA binding
O7A_03765	COG0531	amino acid
O7A_03775	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
O7A_03780	COG1470	cell adhesion involved in biofilm formation
O7A_03785	COG4496	protein, YerC YecD
O7A_03790	COG0069	glutamate synthase activity
O7A_03800	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
O7A_03805	COG0210	DNA helicase
O7A_03810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
O7A_03815	COG4851	CamS sex pheromone cAM373 precursor
O7A_03820	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O7A_03825	COG1285	pathogenesis
O7A_03830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O7A_03835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
O7A_03840	COG0154	amidase activity
O7A_03845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
O7A_03850	COG1309	transcriptional regulator
O7A_03855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
O7A_03860	COG1597	lipid kinase activity
O7A_03865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
O7A_03870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
O7A_03875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
O7A_03880	COG1002	Type II restriction enzyme, methylase subunits
O7A_03885	COG1061	Type III restriction enzyme res subunit
O7A_03890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
O7A_03910	COG5444	nuclease activity
O7A_03915	COG3391	amine dehydrogenase activity
O7A_03920	COG0457	Tetratricopeptide repeat
O7A_03930	COG0217	transcriptional regulatory protein
O7A_03940	COG1309	transcriptional regulator
O7A_03945	COG3631	Ketosteroid isomerase-related protein
O7A_03950	COG0702	epimerase
O7A_03965	COG3546	catalase activity
O7A_03970	COG0454	-acetyltransferase
O7A_03980	COG5578	integral membrane protein
O7A_03985	COG2972	Histidine kinase
O7A_03990	COG2207	Transcriptional regulator
O7A_03990	COG4753	response regulator
O7A_03995	COG1653	transport
O7A_04000	COG1175	transmembrane transport
O7A_04005	COG0395	ABC-type sugar transport system, permease component
O7A_04010	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
O7A_04015	COG2207	Transcriptional regulator
O7A_04020	COG2755	lipolytic protein G-D-S-L family
O7A_04030	COG5578	integral membrane protein
O7A_04035	COG3401	FG-GAP repeat protein
O7A_04040	COG3401	FG-GAP repeat protein
O7A_04045	COG2755	lipolytic protein G-D-S-L family
O7A_04050	COG1874	Beta-galactosidase
O7A_04060	COG1653	transport
O7A_04065	COG4209	transmembrane transport
O7A_04070	COG0395	ABC-type sugar transport system, permease component
O7A_04075	COG1486	melibiose metabolic process
O7A_04080	COG2323	membrane
O7A_04085	COG2329	Antibiotic biosynthesis monooxygenase
O7A_04090	COG0346	lactoylglutathione lyase activity
O7A_04105	COG5583	Uncharacterized small protein (DUF2292)
O7A_04110	COG0670	Belongs to the BI1 family
O7A_04115	COG0697	spore germination
O7A_04120	COG1846	Transcriptional regulator
O7A_04125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
O7A_04135	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
O7A_04135	COG2124	cytochrome p450
O7A_04140	COG1368	sulfuric ester hydrolase activity
O7A_04145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
O7A_04150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7A_04155	COG1442	glycosyl transferase family 8
O7A_04160	COG1216	Glycosyl transferase, family 2
O7A_04165	COG1442	glycosyl transferase family 8
O7A_04170	COG2223	nitrite transmembrane transporter activity
O7A_04175	COG1011	Hydrolase
O7A_04180	COG0531	amino acid
O7A_04185	COG1012	belongs to the aldehyde dehydrogenase family
O7A_04190	COG0840	transmembrane signaling receptor activity
O7A_04195	COG0488	(ABC) transporter
O7A_04205	COG0789	Transcriptional regulator
O7A_04210	COG2814	Major facilitator Superfamily
O7A_04225	COG0488	(ABC) transporter
O7A_04230	COG0513	Belongs to the DEAD box helicase family
O7A_04235	COG0456	acetyltransferase
O7A_04240	COG2130	NADP-dependent
O7A_04255	COG2211	Major facilitator Superfamily
O7A_04260	COG1262	PFAM Formylglycine-generating sulfatase enzyme
O7A_04265	COG1120	ATPase activity
O7A_04270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7A_04275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7A_04280	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
O7A_04295	COG3866	Pectate lyase
O7A_04300	COG0471	metal ion transport
O7A_04305	COG3290	protein histidine kinase activity
O7A_04310	COG4565	transcriptional regulatory protein
O7A_04315	COG3181	Tripartite tricarboxylate transporter family receptor
O7A_04325	COG2851	Citrate transporter
O7A_04330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7A_04335	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
O7A_04340	COG1254	Belongs to the acylphosphatase family
O7A_04345	COG2258	MOSC domain
O7A_04365	COG0024	Methionine aminopeptidase
O7A_04370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7A_04370	COG1263	PTS System
O7A_04375	COG1368	sulfuric ester hydrolase activity
O7A_04385	COG1115	amino acid carrier protein
O7A_04390	COG0531	amino acid
O7A_04405	COG0697	spore germination
O7A_04410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7A_04410	COG1263	PTS System
O7A_04415	COG0366	Alpha amylase catalytic
O7A_04420	COG2188	Transcriptional regulator
O7A_04425	COG0778	Nitroreductase
O7A_04430	COG0737	Belongs to the 5'-nucleotidase family
O7A_04435	COG0693	protein deglycase activity
O7A_04440	COG2814	Major facilitator Superfamily
O7A_04445	COG4840	Belongs to the UPF0435 family
O7A_04450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
O7A_04455	COG4980	gas vesicle protein
O7A_04460	COG1295	ribonuclease BN
O7A_04470	COG0477	Major facilitator Superfamily
O7A_04480	COG0387	Pfam Sodium calcium exchanger
O7A_04490	COG0668	transmembrane transport
O7A_04495	COG0535	radical SAM domain protein
O7A_04505	COG0726	polysaccharide deacetylase
O7A_04510	COG2084	Dehydrogenase
O7A_04515	COG0598	Magnesium transport protein CorA
O7A_04520	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
O7A_04525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
O7A_04535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
O7A_04540	COG4637	Psort location Cytoplasmic, score
O7A_04550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O7A_04555	COG0022	dehydrogenase e1 component
O7A_04560	COG0508	dehydrogenase complex catalyzes the overall conversion of
O7A_04565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O7A_04570	COG3284	Transcriptional regulator
O7A_04580	COG1742	UPF0060 membrane protein
O7A_04605	COG4842	Belongs to the WXG100 family
O7A_04610	COG1486	melibiose metabolic process
O7A_04615	COG1737	Transcriptional regulator
O7A_04620	COG1263	PTS System
O7A_04620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7A_04625	COG1132	(ABC) transporter
O7A_04630	COG1132	(ABC) transporter
O7A_04635	COG2259	Doxx family
O7A_04640	COG2514	catechol 2,3-dioxygenase activity
O7A_04645	COG4977	sequence-specific DNA binding
O7A_04645	COG1917	Cupin 2, conserved barrel domain protein
O7A_04650	COG2814	Major facilitator Superfamily
O7A_04655	COG1082	Xylose isomerase domain protein TIM barrel
O7A_04660	COG0673	inositol 2-dehydrogenase activity
O7A_04665	COG4585	Histidine kinase
O7A_04670	COG2197	response regulator
O7A_04675	COG1131	(ABC) transporter
O7A_04680	COG1511	domain protein
O7A_04680	COG0842	Transport permease protein
O7A_04685	COG0842	Transport permease protein
O7A_04690	COG1695	Transcriptional regulator
O7A_04695	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
O7A_04700	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
O7A_04705	COG1309	transcriptional regulator
O7A_04710	COG2814	Major facilitator Superfamily
O7A_04715	COG2318	DinB family
O7A_04720	COG2814	Major facilitator Superfamily
O7A_04725	COG1846	Transcriptional regulator
O7A_04730	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
O7A_04730	COG0392	lysyltransferase activity
O7A_04735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7A_04740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7A_04745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7A_04750	COG0384	phenazine biosynthesis protein PhzF
O7A_04755	COG0778	Nitroreductase
O7A_04770	COG1090	epimerase
O7A_04775	COG2137	regulation of response to DNA damage stimulus
O7A_04790	COG2814	Major facilitator Superfamily
O7A_04805	COG3103	Sh3 type 3 domain protein
O7A_04810	COG5658	integral membrane protein
O7A_04815	COG0596	Alpha beta hydrolase
O7A_04820	COG0463	Glycosyl transferase, family 2
O7A_04825	COG4485	Bacterial membrane protein, YfhO
O7A_04830	COG1988	membrane-bound metal-dependent
O7A_04835	COG1194	a g-specific adenine glycosylase
O7A_04845	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_04860	COG3557	Belongs to the UPF0374 family
O7A_04865	COG1132	(ABC) transporter
O7A_04870	COG4129	membrane
O7A_04875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
O7A_04880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
O7A_04885	COG0735	belongs to the Fur family
O7A_05000	COG4326	sporulation control protein
O7A_05010	COG5577	PFAM Coat F domain
O7A_05015	COG3340	Belongs to the peptidase S51 family
O7A_05020	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
O7A_05025	COG0277	FAD linked oxidase domain protein
O7A_05035	COG0753	catalase activity
O7A_05040	COG1116	anion transmembrane transporter activity
O7A_05045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
O7A_05050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
O7A_05055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7A_05065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
O7A_05075	COG1476	TRANSCRIPTIONal
O7A_05085	COG3382	B3 4 domain protein
O7A_05090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
O7A_05100	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
O7A_05105	COG0789	Transcriptional regulator
O7A_05110	COG1664	Polymer-forming cytoskeletal
O7A_05115	COG1664	Polymer-forming cytoskeletal
O7A_05120	COG2766	serine protein kinase
O7A_05125	COG2718	Belongs to the UPF0229 family
O7A_05135	COG1846	Transcriptional regulator
O7A_05140	COG1566	PFAM secretion protein HlyD family protein
O7A_05145	COG2814	Major facilitator Superfamily
O7A_05150	COG0655	NAD(P)H dehydrogenase (quinone) activity
O7A_05165	COG1725	Transcriptional regulator
O7A_05170	COG1131	(ABC) transporter
O7A_05175	COG1131	(ABC) transporter
O7A_05180	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
O7A_05185	COG1278	Cold shock
O7A_05195	COG1464	Belongs to the NlpA lipoprotein family
O7A_05200	COG3706	GGDEF domain
O7A_05205	COG1823	symporter activity
O7A_05225	COG5577	PFAM Coat F domain
O7A_05230	COG4085	toxin activity
O7A_05230	COG0737	Belongs to the 5'-nucleotidase family
O7A_05230	COG1525	nuclease
O7A_05235	COG3764	Sortase (surface protein transpeptidase)
O7A_05240	COG0564	pseudouridine synthase activity
O7A_05250	COG0517	IMP dehydrogenase activity
O7A_05255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
O7A_05260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
O7A_05260	COG3153	acetyltransferase
O7A_05265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O7A_05270	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
O7A_05275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
O7A_05280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
O7A_05285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
O7A_05290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
O7A_05295	COG4585	Histidine kinase
O7A_05295	COG2203	Gaf domain
O7A_05300	COG2197	response regulator
O7A_05305	COG0431	NADPH-dependent FMN reductase
O7A_05320	COG1388	LysM domain
O7A_05320	COG0791	NLP P60 protein
O7A_05325	COG1959	2 iron, 2 sulfur cluster binding
O7A_05330	COG0668	transmembrane transport
O7A_05335	COG2719	SpoVR family
O7A_05340	COG1785	Belongs to the alkaline phosphatase family
O7A_05345	COG0791	NLP P60 protein
O7A_05345	COG1388	LysM domain
O7A_05350	COG0583	DNA-binding transcription factor activity
O7A_05355	COG0372	Belongs to the citrate synthase family
O7A_05360	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_05365	COG0531	amino acid
O7A_05370	COG0733	neurotransmitter:sodium symporter activity
O7A_05375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7A_05380	COG0456	acetyltransferase
O7A_05395	COG1595	DNA-templated transcription, initiation
O7A_05400	COG0667	Aldo Keto reductase
O7A_05405	COG0204	Acyl-transferase
O7A_05410	COG1253	flavin adenine dinucleotide binding
O7A_05415	COG0789	Transcriptional regulator
O7A_05420	COG0436	Aminotransferase
O7A_05425	COG1253	flavin adenine dinucleotide binding
O7A_05430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
O7A_05435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
O7A_05440	COG0584	glycerophosphoryl diester phosphodiesterase
O7A_05450	COG0668	transmembrane transport
O7A_05455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
O7A_05460	COG0726	polysaccharide deacetylase
O7A_05465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O7A_05470	COG1757	Na H antiporter
O7A_05475	COG0589	response to stress
O7A_05485	COG1132	(ABC) transporter
O7A_05490	COG1132	(ABC) transporter
O7A_05495	COG0702	epimerase
O7A_05510	COG0189	ligase activity
O7A_05515	COG0189	ligase activity
O7A_05520	COG4399	Belongs to the UPF0754 family
O7A_05525	COG3679	Belongs to the UPF0342 family
O7A_05530	COG4335	DNA alkylation repair
O7A_05535	COG0561	phosphatase activity
O7A_05540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
O7A_05545	COG0475	glutathione-regulated potassium exporter activity
O7A_05550	COG0490	domain, Protein
O7A_05560	COG1024	Enoyl-CoA hydratase
O7A_05570	COG4152	abc transporter atp-binding protein
O7A_05575	COG1668	transmembrane transport
O7A_05580	COG0420	3'-5' exonuclease activity
O7A_05585	COG4717	serine-type aminopeptidase activity
O7A_05590	COG3481	metal-dependent phosphohydrolase, HD sub domain
O7A_05600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
O7A_05625	COG1846	Transcriptional regulator
O7A_05630	COG4980	gas vesicle protein
O7A_05645	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
O7A_05650	COG0537	adenosine 5'-monophosphoramidase activity
O7A_05655	COG1131	(ABC) transporter
O7A_05660	COG4473	ABC transporter
O7A_05670	COG1473	amidohydrolase
O7A_05675	COG3069	C4-dicarboxylate transmembrane transporter activity
O7A_05685	COG2329	Antibiotic biosynthesis monooxygenase
O7A_05690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O7A_05695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
O7A_05710	COG1309	transcriptional regulator
O7A_05715	COG1511	domain protein
O7A_05720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O7A_05725	COG4377	Putative membrane peptidase family (DUF2324)
O7A_05735	COG1363	Peptidase, m42
O7A_05740	COG4405	Protein conserved in bacteria
O7A_05745	COG1301	dicarboxylic acid transport
O7A_05755	COG1234	tRNA 3'-trailer cleavage
O7A_05760	COG0095	Lipoate-protein ligase
O7A_05765	COG0702	epimerase
O7A_05770	COG0318	PFAM AMP-dependent synthetase and ligase
O7A_05780	COG0501	Belongs to the peptidase M48B family
O7A_05785	COG1404	Belongs to the peptidase S8 family
O7A_05790	COG0456	acetyltransferase
O7A_05795	COG0604	alcohol dehydrogenase
O7A_05800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
O7A_05805	COG0406	alpha-ribazole phosphatase activity
O7A_05810	COG0183	Belongs to the thiolase family
O7A_05815	COG0318	PFAM AMP-dependent synthetase and ligase
O7A_05820	COG1268	BioY protein
O7A_05825	COG0840	transmembrane signaling receptor activity
O7A_05830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O7A_05830	COG0723	plastoquinol--plastocyanin reductase activity
O7A_05835	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_05845	COG4903	ComK protein
O7A_05850	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_05860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O7A_05875	COG0398	Pfam SNARE associated Golgi protein
O7A_05880	COG0681	Belongs to the peptidase S26 family
O7A_05885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
O7A_05890	COG1846	Transcriptional regulator
O7A_05895	COG0738	Major facilitator superfamily
O7A_05900	COG0673	inositol 2-dehydrogenase activity
O7A_05905	COG0561	phosphatase activity
O7A_05910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O7A_05915	COG1609	Transcriptional regulator
O7A_05920	COG3180	Ammonia monooxygenase
O7A_05925	COG0477	Major facilitator Superfamily
O7A_05925	COG2814	Major facilitator Superfamily
O7A_05930	COG4533	DNA binding
O7A_05940	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
O7A_05945	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
O7A_05950	COG1074	ATP-dependent DNA helicase activity
O7A_05955	COG0420	3'-5' exonuclease activity
O7A_05960	COG0419	ATPase involved in DNA repair
O7A_05965	COG1403	HNH endonuclease
O7A_06010	COG5337	Spore coat protein CotH
O7A_06015	COG0179	Fumarylacetoacetate (FAA) hydrolase
O7A_06025	COG1404	Belongs to the peptidase S8 family
O7A_06035	COG0367	asparagine synthase
O7A_06040	COG2318	DinB family
O7A_06045	COG1562	ergosterol biosynthetic process
O7A_06050	COG0534	Mate efflux family protein
O7A_06055	COG2207	Transcriptional regulator
O7A_06055	COG1917	Cupin 2, conserved barrel domain protein
O7A_06060	COG1609	Transcriptional regulator
O7A_06065	COG0673	inositol 2-dehydrogenase activity
O7A_06070	COG2318	DinB family
O7A_06075	COG1279	arginine transmembrane transporter activity
O7A_06080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O7A_06085	COG1357	PFAM Pentapeptide repeats (8 copies)
O7A_06090	COG2267	carboxylic ester hydrolase activity
O7A_06095	COG0529	Catalyzes the synthesis of activated sulfate
O7A_06100	COG2046	Belongs to the sulfate adenylyltransferase family
O7A_06105	COG0175	sulfate reduction
O7A_06110	COG2045	Belongs to the ComB family
O7A_06115	COG1809	phosphosulfolactate synthase activity
O7A_06120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7A_06125	COG4948	Mandelate Racemase Muconate Lactonizing
O7A_06130	COG2814	Major facilitator Superfamily
O7A_06135	COG0454	-acetyltransferase
O7A_06140	COG2153	protein acetylation
O7A_06145	COG0646	methionine synthase
O7A_06145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
O7A_06150	COG1666	GTP binding
O7A_06155	COG2996	Protein conserved in bacteria
O7A_06175	COG1695	Transcriptional regulator
O7A_06190	COG3227	Zinc metalloprotease (Elastase)
O7A_06195	COG1307	EDD domain protein, DegV family
O7A_06200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7A_06220	COG0561	phosphatase activity
O7A_06225	COG1073	alpha beta
O7A_06230	COG2151	metal-sulfur cluster biosynthetic enzyme
O7A_06240	COG0277	FAD linked oxidase domain protein
O7A_06245	COG2271	Major facilitator Superfamily
O7A_06250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
O7A_06265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
O7A_06270	COG0505	Belongs to the CarA family
O7A_06275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
O7A_06280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
O7A_06295	COG2267	carboxylic ester hydrolase activity
O7A_06305	COG1744	ABC transporter substrate-binding protein PnrA-like
O7A_06320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O7A_06325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
O7A_06330	COG5504	Zn-dependent protease
O7A_06335	COG0444	Belongs to the ABC transporter superfamily
O7A_06340	COG4608	Belongs to the ABC transporter superfamily
O7A_06350	COG0601	transmembrane transport
O7A_06355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O7A_06365	COG0180	Tryptophanyl-tRNA synthetase
O7A_06370	COG4166	transmembrane transport
O7A_06375	COG0601	transmembrane transport
O7A_06380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O7A_06385	COG0444	Belongs to the ABC transporter superfamily
O7A_06390	COG4608	Belongs to the ABC transporter superfamily
O7A_06395	COG2814	Major facilitator Superfamily
O7A_06400	COG0456	acetyltransferase
O7A_06405	COG1393	Belongs to the ArsC family
O7A_06410	COG0861	Integral membrane protein TerC family
O7A_06415	COG4862	establishment of competence for transformation
O7A_06420	COG4469	Competence protein
O7A_06425	COG1164	Oligoendopeptidase f
O7A_06445	COG2346	COG2346, Truncated hemoglobins
O7A_06450	COG0741	lytic transglycosylase activity
O7A_06455	COG4116	CYTH
O7A_06465	COG2357	RelA SpoT domain protein
O7A_06470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
O7A_06475	COG0564	pseudouridine synthase activity
O7A_06480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
O7A_06485	COG0569	domain protein
O7A_06485	COG0475	glutathione-regulated potassium exporter activity
O7A_06490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
O7A_06495	COG0352	thiamine-phosphate diphosphorylase activity
O7A_06500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O7A_06505	COG2104	thiamine diphosphate biosynthetic process
O7A_06510	COG2022	thiamine diphosphate biosynthetic process
O7A_06515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O7A_06520	COG0351	phosphomethylpyrimidine kinase
O7A_06525	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
O7A_06585	COG0210	DNA helicase
O7A_06595	COG2153	protein acetylation
O7A_06600	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
O7A_06605	COG2382	esterase
O7A_06610	COG0626	cystathionine gamma-synthase activity
O7A_06615	COG0626	cystathionine gamma-synthase activity
O7A_06620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7A_06625	COG5505	Protein of unknown function (DUF819)
O7A_06660	COG3677	Transposase
O7A_06675	COG5484	DNA packaging
O7A_06680	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
O7A_06685	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_06695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7A_06695	COG3711	transcriptional antiterminator
O7A_06700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O7A_06700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O7A_06700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7A_06705	COG1482	cell wall glycoprotein biosynthetic process
O7A_06715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7A_06725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
O7A_06740	COG0109	protoheme IX farnesyltransferase activity
O7A_06750	COG0726	polysaccharide deacetylase
O7A_06770	COG5504	Zn-dependent protease
O7A_06775	COG2205	protein histidine kinase activity
O7A_06785	COG3383	formate dehydrogenase (NAD+) activity
O7A_06790	COG2427	Protein of unknown function (DUF1641)
O7A_06800	COG1051	belongs to the nudix hydrolase family
O7A_06810	COG2124	cytochrome p450
O7A_06815	COG1819	glycosyl
O7A_06825	COG1587	Uroporphyrinogen-III synthase
O7A_06830	COG0390	transport system, permease component
O7A_06835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
O7A_06840	COG0697	spore germination
O7A_06845	COG4297	protein containing double-stranded beta helix domain
O7A_06855	COG1252	NADH dehydrogenase
O7A_06860	COG1904	glucuronate isomerase
O7A_06865	COG2211	Major facilitator Superfamily
O7A_06870	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
O7A_06875	COG1063	alcohol dehydrogenase
O7A_06880	COG1312	Catalyzes the dehydration of D-mannonate
O7A_06885	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_06890	COG2271	Major facilitator Superfamily
O7A_06895	COG1609	Transcriptional regulator
O7A_06900	COG0246	Mannitol dehydrogenase
O7A_06905	COG2721	sulfolactate sulfo-lyase activity
O7A_06910	COG0730	response to heat
O7A_06915	COG2318	DinB family
O7A_06920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
O7A_06925	COG0457	Tetratricopeptide repeat
O7A_06935	COG2350	Protein conserved in bacteria
O7A_06940	COG3409	Peptidoglycan-binding domain 1 protein
O7A_06940	COG5632	N-Acetylmuramoyl-L-alanine amidase
O7A_06940	COG1388	LysM domain
O7A_06950	COG4195	phage-related replication protein
O7A_06955	COG3546	catalase activity
O7A_06960	COG2856	Zn peptidase
O7A_06965	COG1396	sequence-specific DNA binding
O7A_06975	COG1522	sequence-specific DNA binding
O7A_06980	COG1484	DNA-dependent DNA replication
O7A_07005	COG1595	DNA-templated transcription, initiation
O7A_07010	COG3728	DNA packaging
O7A_07010	COG5484	DNA packaging
O7A_07015	COG1783	phage Terminase large subunit
O7A_07020	COG5518	Phage portal protein
O7A_07025	COG0338	D12 class N6 adenine-specific DNA methyltransferase
O7A_07030	COG4653	Phage capsid family
O7A_07080	COG5412	phage tail tape measure protein
O7A_07080	COG3953	SLT domain
O7A_07085	COG1652	LysM domain
O7A_07090	COG4193	domain, Protein
O7A_07100	COG3628	GPW Gp25 family protein
O7A_07105	COG3299	homolog of phage Mu protein gp47
O7A_07110	COG3778	Protein conserved in bacteria
O7A_07150	COG3409	Peptidoglycan-binding domain 1 protein
O7A_07150	COG5632	N-Acetylmuramoyl-L-alanine amidase
O7A_07165	COG0306	phosphate transporter
O7A_07170	COG1392	Phosphate transport regulator
O7A_07175	COG0531	amino acid
O7A_07180	COG0346	lactoylglutathione lyase activity
O7A_07185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
O7A_07190	COG0463	Glycosyl transferase, family 2
O7A_07200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O7A_07205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O7A_07210	COG2362	D-Aminopeptidase
O7A_07215	COG0601	transmembrane transport
O7A_07220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O7A_07225	COG0444	Belongs to the ABC transporter superfamily
O7A_07230	COG4166	transmembrane transport
O7A_07235	COG1619	proteins homologs of microcin C7 resistance protein MccF
O7A_07240	COG4948	Mandelate Racemase Muconate Lactonizing
O7A_07245	COG0791	NLP P60 protein
O7A_07250	COG4608	Belongs to the ABC transporter superfamily
O7A_07255	COG2706	6-phosphogluconolactonase activity
O7A_07260	COG1834	amidinotransferase
O7A_07265	COG1607	acyl-coa hydrolase
O7A_07270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
O7A_07270	COG1017	nitric oxide dioxygenase activity
O7A_07280	COG2323	membrane
O7A_07285	COG2318	DinB family
O7A_07290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7A_07295	COG2076	Multidrug Resistance protein
O7A_07300	COG2076	Multidrug Resistance protein
O7A_07305	COG0788	formyltetrahydrofolate deformylase activity
O7A_07310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
O7A_07315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
O7A_07320	COG1764	response to oxidative stress
O7A_07325	COG1846	Transcriptional regulator
O7A_07330	COG1764	response to oxidative stress
O7A_07340	COG0590	tRNA wobble adenosine to inosine editing
O7A_07345	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
O7A_07350	COG1404	Belongs to the peptidase S8 family
O7A_07355	COG1366	Belongs to the anti-sigma-factor antagonist family
O7A_07360	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
O7A_07365	COG1122	ATPase activity
O7A_07370	COG4721	ABC-type cobalt transport system, permease component
O7A_07380	COG0745	RESPONSE REGULATOR receiver
O7A_07385	COG3850	Histidine kinase
O7A_07385	COG5002	protein histidine kinase activity
O7A_07390	COG3212	peptidase
O7A_07395	COG3212	peptidase
O7A_07415	COG2239	Acts as a magnesium transporter
O7A_07420	COG0789	Transcriptional regulator
O7A_07435	COG1846	Transcriptional regulator
O7A_07440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
O7A_07445	COG0726	polysaccharide deacetylase
O7A_07450	COG1408	metallophosphoesterase
O7A_07460	COG0463	Glycosyl transferase, family 2
O7A_07465	COG3285	dna ligase
O7A_07465	COG1793	dna ligase
O7A_07470	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
O7A_07475	COG5001	Diguanylate cyclase
O7A_07475	COG3300	MHYT domain
O7A_07480	COG0586	Pfam SNARE associated Golgi protein
O7A_07485	COG0861	Integral membrane protein TerC family
O7A_07490	COG1191	sigma factor activity
O7A_07510	COG0501	Belongs to the peptidase M48B family
O7A_07515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
O7A_07530	COG3594	Acyltransferase
O7A_07535	COG5002	protein histidine kinase activity
O7A_07540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
O7A_07550	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
O7A_07555	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
O7A_07560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
O7A_07565	COG0436	Aminotransferase
O7A_07570	COG1850	ribulose-bisphosphate carboxylase activity
O7A_07575	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
O7A_07580	COG0235	Class ii aldolase
O7A_07585	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
O7A_07590	COG3339	Conserved Protein
O7A_07605	COG3852	Histidine kinase
O7A_07610	COG1846	Transcriptional regulator
O7A_07615	COG1360	Flagellar Motor Protein
O7A_07620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
O7A_07625	COG0542	response to heat
O7A_07630	COG3949	Membrane
O7A_07635	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
O7A_07640	COG0720	synthase
O7A_07645	COG0602	queuosine metabolic process
O7A_07650	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
O7A_07655	COG1733	regulation of RNA biosynthetic process
O7A_07660	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_07665	COG1388	LysM domain
O7A_07665	COG4641	Protein conserved in bacteria
O7A_07670	COG1388	LysM domain
O7A_07675	COG3858	chitin binding
O7A_07680	COG3858	chitin binding
O7A_07690	COG4873	Protein conserved in bacteria
O7A_07705	COG3773	Cell wall hydrolase
O7A_07710	COG2244	polysaccharide biosynthetic process
O7A_07715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_07720	COG2217	Heavy metal translocating P-type atpase
O7A_07730	COG0006	proline dipeptidase activity
O7A_07740	COG1609	Transcriptional regulator
O7A_07745	COG3711	transcriptional antiterminator
O7A_07750	COG1263	PTS System
O7A_07750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7A_07750	COG2190	(PTS) system
O7A_07755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7A_07760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
O7A_07770	COG1533	DNA photolyase activity
O7A_07775	COG0456	acetyltransferase
O7A_07780	COG0840	transmembrane signaling receptor activity
O7A_07785	COG2084	Dehydrogenase
O7A_07790	COG2340	Cysteine-rich secretory protein family
O7A_07795	COG0768	penicillin binding
O7A_07800	COG4191	Histidine kinase
O7A_07805	COG0436	Aminotransferase
O7A_07815	COG0835	chemotaxis
O7A_07815	COG0784	Response regulator, receiver
O7A_07825	COG2814	Major facilitator Superfamily
O7A_07830	COG1376	ErfK ybiS ycfS ynhG family protein
O7A_07835	COG1408	metallophosphoesterase
O7A_07840	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_07845	COG3409	Peptidoglycan-binding domain 1 protein
O7A_07850	COG3409	Peptidoglycan-binding domain 1 protein
O7A_07860	COG2200	EAL domain
O7A_07870	COG4703	Protein of unknown function (DUF1797)
O7A_07875	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
O7A_07885	COG0517	IMP dehydrogenase activity
O7A_07890	COG0583	DNA-binding transcription factor activity
O7A_07895	COG0716	FMN binding
O7A_07905	COG0716	FMN binding
O7A_07910	COG2171	N-acyltransferase activity
O7A_07915	COG1473	amidohydrolase
O7A_07925	COG0668	transmembrane transport
O7A_07930	COG0450	alkyl hydroperoxide reductase
O7A_07935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_07950	COG0746	molybdenum cofactor guanylyltransferase activity
O7A_07955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O7A_07960	COG0303	'Molybdopterin
O7A_07965	COG1763	Mo-molybdopterin cofactor biosynthetic process
O7A_07970	COG0314	molybdopterin synthase activity
O7A_07975	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
O7A_07980	COG1132	(ABC) transporter
O7A_07985	COG1132	(ABC) transporter
O7A_07995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
O7A_08000	COG1136	(ABC) transporter
O7A_08005	COG0577	efflux transmembrane transporter activity
O7A_08010	COG1349	DNA-binding transcription factor activity
O7A_08015	COG1105	Belongs to the carbohydrate kinase PfkB family
O7A_08020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O7A_08020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7A_08020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O7A_08025	COG0681	Belongs to the peptidase S26 family
O7A_08035	COG0488	(ABC) transporter
O7A_08040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
O7A_08045	COG2309	aminopeptidase activity
O7A_08055	COG1077	Cell shape determining protein MreB Mrl
O7A_08060	COG2002	toxin-antitoxin pair type II binding
O7A_08065	COG3852	Histidine kinase
O7A_08070	COG2105	PFAM AIG2 family protein
O7A_08070	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
O7A_08075	COG0569	domain protein
O7A_08080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
O7A_08085	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
O7A_08095	COG0561	phosphatase activity
O7A_08100	COG0242	peptide deformylase activity
O7A_08110	COG0497	DNA recombination
O7A_08115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O7A_08120	COG0022	dehydrogenase e1 component
O7A_08125	COG0508	dehydrogenase complex catalyzes the overall conversion of
O7A_08130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O7A_08135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_08140	COG1982	Orn Lys Arg decarboxylase major
O7A_08145	COG4476	Belongs to the UPF0223 family
O7A_08150	COG4493	Belongs to the UPF0637 family
O7A_08160	COG0483	inositol monophosphate 1-phosphatase activity
O7A_08170	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
O7A_08190	COG1595	DNA-templated transcription, initiation
O7A_08220	COG4896	Protein conserved in bacteria
O7A_08230	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
O7A_08235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
O7A_08240	COG2066	Belongs to the glutaminase family
O7A_08245	COG4838	Belongs to the UPF0358 family
O7A_08250	COG0772	Belongs to the SEDS family
O7A_08255	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
O7A_08260	COG1612	heme a metabolic process
O7A_08265	COG0109	protoheme IX farnesyltransferase activity
O7A_08270	COG2010	Cytochrome c
O7A_08270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
O7A_08275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
O7A_08280	COG1845	cytochrome c oxidase, subunit III
O7A_08285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
O7A_08290	COG3336	cytochrome c oxidase
O7A_08300	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
O7A_08305	COG2340	Cysteine-rich secretory protein family
O7A_08320	COG3679	Belongs to the UPF0342 family
O7A_08325	COG4471	UPF0298 protein
O7A_08330	COG0742	ribosomal rna small subunit methyltransferase
O7A_08335	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
O7A_08340	COG3314	Sporulation integral membrane protein YlbJ
O7A_08345	COG1752	Esterase of the alpha-beta hydrolase superfamily
O7A_08350	COG3480	Lon protease (S16) C-terminal proteolytic domain
O7A_08355	COG1323	Belongs to the UPF0348 family
O7A_08365	COG1399	metal-binding, possibly nucleic acid-binding protein
O7A_08370	COG0333	Belongs to the bacterial ribosomal protein bL32 family
O7A_08380	COG0454	-acetyltransferase
O7A_08385	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
O7A_08390	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
O7A_08395	COG2001	Belongs to the MraZ family
O7A_08400	COG0275	rRNA processing
O7A_08405	COG4839	cell division protein FtsL
O7A_08420	COG0768	penicillin binding
O7A_08430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
O7A_08440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
O7A_08445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
O7A_08450	COG0772	Belongs to the SEDS family
O7A_08455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
O7A_08460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
O7A_08465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
O7A_08470	COG3879	Bacterial protein of unknown function (DUF881)
O7A_08475	COG3879	Bacterial protein of unknown function (DUF881)
O7A_08480	COG3856	small basic protein
O7A_08485	COG0849	cell division
O7A_08490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
O7A_08495	COG4412	M6 family metalloprotease domain protein
O7A_08495	COG1404	Belongs to the peptidase S8 family
O7A_08505	COG1191	sigma factor activity
O7A_08510	COG1191	sigma factor activity
O7A_08515	COG1119	ATPase activity
O7A_08520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O7A_08525	COG1873	PFAM PRC-barrel domain
O7A_08535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
O7A_08540	COG1799	cell septum assembly
O7A_08545	COG0762	integral membrane protein
O7A_08550	COG2302	S4 RNA-binding domain
O7A_08555	COG3599	regulation of cell shape
O7A_08560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
O7A_08565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O7A_08570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
O7A_08575	COG0564	pseudouridine synthase activity
O7A_08580	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
O7A_08585	COG2233	PERMEase
O7A_08590	COG0540	Belongs to the ATCase OTCase family
O7A_08595	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
O7A_08600	COG0505	Belongs to the CarA family
O7A_08605	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
O7A_08610	COG0543	2 iron, 2 sulfur cluster binding
O7A_08615	COG0167	dihydroorotate dehydrogenase activity
O7A_08620	COG0284	orotidine-5'-phosphate decarboxylase activity
O7A_08625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
O7A_08635	COG0175	sulfate reduction
O7A_08640	COG0306	phosphate transporter
O7A_08645	COG2046	Belongs to the sulfate adenylyltransferase family
O7A_08650	COG0529	Catalyzes the synthesis of activated sulfate
O7A_08655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
O7A_08660	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
O7A_08665	COG1648	precorrin-2 dehydrogenase activity
O7A_08675	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
O7A_08680	COG1561	YicC-like family, N-terminal region
O7A_08685	COG2052	Domain of unknown function (DUF370)
O7A_08690	COG0194	GDP metabolic process
O7A_08695	COG1758	RNA polymerase activity
O7A_08700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
O7A_08705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
O7A_08710	COG0242	peptide deformylase activity
O7A_08715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
O7A_08720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
O7A_08720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
O7A_08725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
O7A_08730	COG0631	protein serine/threonine phosphatase activity
O7A_08735	COG2815	serine threonine protein kinase
O7A_08735	COG0515	serine threonine protein kinase
O7A_08740	COG1162	GTPase activity
O7A_08745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
O7A_08750	COG1564	THIamine pyrophosphokinase
O7A_08760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
O7A_08765	COG1302	Protein conserved in bacteria
O7A_08770	COG1461	Dihydroxyacetone kinase
O7A_08775	COG1760	l-serine dehydratase
O7A_08780	COG1760	l-serine dehydratase
O7A_08785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
O7A_08790	COG1349	DNA-binding transcription factor activity
O7A_08790	COG2050	protein possibly involved in aromatic compounds catabolism
O7A_08795	COG0416	fatty acid biosynthetic process
O7A_08800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
O7A_08805	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_08810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7A_08815	COG0571	ribonuclease III activity
O7A_08820	COG1196	nuclear chromosome segregation
O7A_08825	COG0552	protein localization to endoplasmic reticulum
O7A_08835	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
O7A_08840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
O7A_08845	COG0228	four-way junction DNA binding
O7A_08850	COG1837	Belongs to the UPF0109 family
O7A_08860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
O7A_08865	COG0336	Belongs to the RNA methyltransferase TrmD family
O7A_08870	COG0335	large ribosomal subunit rRNA binding
O7A_08875	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
O7A_08880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
O7A_08890	COG2257	FlhB HrpN YscU SpaS Family
O7A_08895	COG0045	succinate-CoA ligase (ADP-forming) activity
O7A_08900	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
O7A_08905	COG0758	DNA mediated transformation
O7A_08910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
O7A_08915	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
O7A_08920	COG4974	Belongs to the 'phage' integrase family
O7A_08925	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
O7A_08930	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
O7A_08935	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
O7A_08940	COG1815	bacterial-type flagellum-dependent cell motility
O7A_08945	COG1558	bacterial-type flagellum-dependent cell motility
O7A_08950	COG1677	Flagellar hook-basal body complex protein FliE
O7A_08960	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O7A_08965	COG1317	bacterial-type flagellum organization
O7A_08970	COG1157	protein secretion by the type III secretion system
O7A_08975	COG2882	bacterial-type flagellum organization
O7A_08980	COG3334	PFAM MgtE intracellular
O7A_08985	COG3144	bacterial-type flagellum assembly
O7A_08990	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
O7A_08995	COG4786	Flagellar basal body rod
O7A_09000	COG1582	Flagellar protein (FlbD)
O7A_09005	COG1580	Controls the rotational direction of flagella during chemotaxis
O7A_09010	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O7A_09015	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O7A_09015	COG1776	CheC inhibitor of MCP methylation
O7A_09020	COG2201	protein-glutamate methylesterase activity
O7A_09025	COG3190	flagellar
O7A_09030	COG1338	Plays a role in the flagellum-specific transport system
O7A_09035	COG1987	bacterial-type flagellum assembly
O7A_09040	COG1684	flagellar biosynthetic protein fliR
O7A_09045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
O7A_09050	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
O7A_09055	COG1419	protein localization to endoplasmic reticulum
O7A_09060	COG0455	bacterial-type flagellum organization
O7A_09065	COG2201	protein-glutamate methylesterase activity
O7A_09070	COG0643	Histidine kinase
O7A_09070	COG2198	Histidine kinase
O7A_09075	COG0835	chemotaxis
O7A_09080	COG1776	CheC inhibitor of MCP methylation
O7A_09085	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
O7A_09090	COG1191	sigma factor activity
O7A_09100	COG0052	Belongs to the universal ribosomal protein uS2 family
O7A_09105	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
O7A_09110	COG0528	UMP kinase activity
O7A_09115	COG0233	cytoplasmic translational termination
O7A_09120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
O7A_09125	COG4589	Belongs to the CDS family
O7A_09130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
O7A_09135	COG0750	zinc metalloprotease
O7A_09140	COG0442	prolyl-tRNA aminoacylation
O7A_09145	COG2176	DNA-directed DNA polymerase activity
O7A_09150	COG0779	Required for maturation of 30S ribosomal subunits
O7A_09155	COG0195	Participates in both transcription termination and antitermination
O7A_09160	COG2740	Nucleic-acid-binding protein implicated in transcription termination
O7A_09165	COG1358	cellular component organization or biogenesis
O7A_09170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
O7A_09175	COG1550	Protein conserved in bacteria
O7A_09180	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
O7A_09185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
O7A_09190	COG0196	riboflavin kinase activity
O7A_09195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
O7A_09200	COG1185	polyribonucleotide nucleotidyltransferase activity
O7A_09205	COG0726	polysaccharide deacetylase
O7A_09210	COG0612	Peptidase, M16
O7A_09215	COG1873	PFAM PRC-barrel domain
O7A_09225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
O7A_09230	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
O7A_09235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
O7A_09240	COG0527	aspartate kinase activity
O7A_09245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
O7A_09250	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
O7A_09255	COG0740	serine-type endopeptidase activity
O7A_09265	COG4980	gas vesicle protein
O7A_09265	COG1674	ftsk spoiiie
O7A_09270	COG2188	Transcriptional regulator
O7A_09275	COG2814	Major facilitator Superfamily
O7A_09280	COG0612	Peptidase, M16
O7A_09285	COG0612	Peptidase, M16
O7A_09290	COG0300	oxidoreductase activity
O7A_09305	COG1426	Protein conserved in bacteria
O7A_09310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
O7A_09315	COG1058	Belongs to the CinA family
O7A_09315	COG1546	Belongs to the CinA family
O7A_09320	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
O7A_09325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O7A_09330	COG1418	mRNA catabolic process
O7A_09335	COG1692	metallophosphoesterase
O7A_09340	COG2359	stage V sporulation protein S
O7A_09345	COG1063	alcohol dehydrogenase
O7A_09350	COG0156	8-amino-7-oxononanoate synthase activity
O7A_09355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
O7A_09360	COG4550	Control of competence regulator ComK, YlbF/YmcA
O7A_09370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
O7A_09375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
O7A_09395	COG3226	Transcriptional regulator
O7A_09400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7A_09410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
O7A_09415	COG3321	synthase
O7A_09420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
O7A_09420	COG2070	2-Nitropropane dioxygenase
O7A_09425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7A_09430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
O7A_09435	COG3425	synthase
O7A_09440	COG1024	Enoyl-CoA hydratase
O7A_09445	COG1024	Enoyl-CoA hydratase
O7A_09450	COG0318	PFAM AMP-dependent synthetase and ligase
O7A_09450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_09450	COG3321	synthase
O7A_09450	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_09450	COG0300	oxidoreductase activity
O7A_09455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7A_09455	COG4221	oxidoreductase activity
O7A_09455	COG0300	oxidoreductase activity
O7A_09455	COG3321	synthase
O7A_09460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7A_09460	COG3321	synthase
O7A_09460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_09460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7A_09460	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_09465	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_09465	COG3321	synthase
O7A_09465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_09465	COG4221	oxidoreductase activity
O7A_09470	COG3321	synthase
O7A_09470	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
O7A_09470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
O7A_09470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7A_09475	COG2124	cytochrome p450
O7A_09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7A_09490	COG1404	Belongs to the peptidase S8 family
O7A_09500	COG4195	phage-related replication protein
O7A_09505	COG1764	response to oxidative stress
O7A_09510	COG2076	Multidrug Resistance protein
O7A_09515	COG2076	Multidrug Resistance protein
O7A_09530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
O7A_09535	COG1923	regulation of RNA biosynthetic process
O7A_09550	COG1780	Probably involved in ribonucleotide reductase function
O7A_09555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
O7A_09560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
O7A_09565	COG4112	unkown
O7A_09570	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7A_09575	COG0464	growth
O7A_09585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
O7A_09590	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
O7A_09595	COG0789	Transcriptional regulator
O7A_09600	COG0174	glutamine synthetase
O7A_09620	COG4282	regulation of fungal-type cell wall biogenesis
O7A_09630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7A_09655	COG0135	phosphoribosylanthranilate isomerase activity
O7A_09660	COG2211	Major facilitator Superfamily
O7A_09665	COG3507	Belongs to the glycosyl hydrolase 43 family
O7A_09670	COG1940	carbohydrate kinase activity
O7A_09675	COG2115	Belongs to the xylose isomerase family
O7A_09680	COG1070	Carbohydrate kinase
O7A_09685	COG1525	nuclease
O7A_09690	COG2814	Major facilitator Superfamily
O7A_09695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O7A_09705	COG0756	dUTP diphosphatase activity
O7A_09715	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
O7A_09740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
O7A_09755	COG3832	glyoxalase III activity
O7A_09770	COG0697	spore germination
O7A_09775	COG0531	amino acid
O7A_09805	COG4195	phage-related replication protein
O7A_09815	COG0346	lactoylglutathione lyase activity
O7A_09825	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
O7A_09830	COG1388	LysM domain
O7A_09835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
O7A_09840	COG4224	UPF0291 protein
O7A_09845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
O7A_09855	COG3763	UPF0154 protein
O7A_09865	COG0785	Cytochrome C biogenesis protein
O7A_09870	COG2201	protein-glutamate methylesterase activity
O7A_09875	COG4846	Membrane protein involved in cytochrome C biogenesis
O7A_09885	COG0071	Belongs to the small heat shock protein (HSP20) family
O7A_09900	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
O7A_09905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_09925	COG0824	Thioesterase
O7A_09935	COG4841	protein insertion into membrane
O7A_09940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
O7A_09945	COG1832	CoA-binding protein
O7A_09950	COG0187	DNA topoisomerase II activity
O7A_09955	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
O7A_09970	COG1115	amino acid carrier protein
O7A_09975	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
O7A_09985	COG5520	Belongs to the glycosyl hydrolase 30 family
O7A_09990	COG3507	Belongs to the glycosyl hydrolase 43 family
O7A_09995	COG2246	polysaccharide biosynthetic process
O7A_10000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
O7A_10005	COG0586	Pfam SNARE associated Golgi protein
O7A_10010	COG2404	hydrolase activity, acting on ester bonds
O7A_10015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
O7A_10020	COG1024	Enoyl-CoA hydratase
O7A_10025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
O7A_10030	COG0511	ligase activity, forming carbon-carbon bonds
O7A_10035	COG0439	Biotin carboxylase
O7A_10040	COG0318	PFAM AMP-dependent synthetase and ligase
O7A_10045	COG1960	acyl-CoA dehydrogenase activity
O7A_10060	COG1649	PFAM Uncharacterised BCR, COG1649
O7A_10070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_10070	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
O7A_10075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_10080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_10085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_10090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_10095	COG2027	D-alanyl-D-alanine carboxypeptidase
O7A_10100	COG2017	converts alpha-aldose to the beta-anomer
O7A_10105	COG0534	Mate efflux family protein
O7A_10120	COG0582	viral genome integration into host DNA
O7A_10125	COG0166	Belongs to the GPI family
O7A_10130	COG0405	Gamma-glutamyltransferase
O7A_10135	COG0583	DNA-binding transcription factor activity
O7A_10140	COG0604	alcohol dehydrogenase
O7A_10145	COG0493	'glutamate synthase
O7A_10150	COG0070	glutamate synthase
O7A_10150	COG0069	glutamate synthase activity
O7A_10150	COG0067	glutamate synthase
O7A_10155	COG0583	DNA-binding transcription factor activity
O7A_10160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
O7A_10165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O7A_10175	COG0300	oxidoreductase activity
O7A_10180	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
O7A_10190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7A_10195	COG2814	Major facilitator Superfamily
O7A_10200	COG1070	Carbohydrate kinase
O7A_10205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
O7A_10210	COG0243	molybdopterin cofactor binding
O7A_10235	COG0840	transmembrane signaling receptor activity
O7A_10235	COG5278	phosphoserine phosphatase activity
O7A_10240	COG2368	4-hydroxyphenylacetate
O7A_10245	COG4305	rare lipoprotein A
O7A_10250	COG3619	membrane
O7A_10255	COG3866	Pectate lyase
O7A_10260	COG2135	peptidase activity
O7A_10270	COG2140	Oxalate decarboxylase
O7A_10280	COG0456	acetyltransferase
O7A_10295	COG2720	vancomycin resistance protein
O7A_10305	COG3655	Transcriptional regulator
O7A_10310	COG3739	integral membrane protein
O7A_10315	COG0583	DNA-binding transcription factor activity
O7A_10320	COG0697	spore germination
O7A_10330	COG0693	protein deglycase activity
O7A_10335	COG2367	Beta-lactamase
O7A_10355	COG0574	Belongs to the PEP-utilizing enzyme family
O7A_10355	COG3848	Pyruvate phosphate dikinase
O7A_10360	COG0726	polysaccharide deacetylase
O7A_10365	COG2314	TM2 domain
O7A_10370	COG1396	sequence-specific DNA binding
O7A_10385	COG2135	peptidase activity
O7A_10390	COG1793	dna ligase
O7A_10420	COG0457	Tetratricopeptide repeat
O7A_10430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O7A_10435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O7A_10450	COG5290	Psort location Cytoplasmic, score
O7A_10470	COG5444	nuclease activity
O7A_10475	COG4282	regulation of fungal-type cell wall biogenesis
O7A_10480	COG1231	oxidoreductase activity
O7A_10485	COG5434	Belongs to the glycosyl hydrolase 28 family
O7A_10490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O7A_10495	COG0662	Cupin 2, conserved barrel domain protein
O7A_10495	COG2207	Transcriptional regulator
O7A_10500	COG0456	acetyltransferase
O7A_10505	COG1309	transcriptional regulator
O7A_10510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7A_10515	COG3708	Transcriptional regulator
O7A_10520	COG2378	regulation of single-species biofilm formation
O7A_10530	COG0640	Transcriptional regulator
O7A_10535	COG0741	lytic transglycosylase activity
O7A_10540	COG2322	membrane
O7A_10555	COG1619	proteins homologs of microcin C7 resistance protein MccF
O7A_10560	COG3239	Fatty acid desaturase
O7A_10565	COG4585	Histidine kinase
O7A_10570	COG2197	response regulator
O7A_10575	COG3584	3D domain protein
O7A_10575	COG1388	LysM domain
O7A_10580	COG0514	ATP-dependent DNA helicase (RecQ)
O7A_10590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
O7A_10595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O7A_10610	COG0071	Belongs to the small heat shock protein (HSP20) family
O7A_10635	COG1012	belongs to the aldehyde dehydrogenase family
O7A_10640	COG1657	PFAM Prenyltransferase squalene oxidase
O7A_10645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
O7A_10650	COG0733	neurotransmitter:sodium symporter activity
O7A_10655	COG0385	Bile acid
O7A_10660	COG0508	dehydrogenase complex catalyzes the overall conversion of
O7A_10665	COG0567	Dehydrogenase, E1 component
O7A_10670	COG4548	von Willebrand factor, type A
O7A_10675	COG0714	Associated with various cellular activities
O7A_10680	COG2032	superoxide dismutase activity
O7A_10685	COG0791	NLP P60 protein
O7A_10685	COG1388	LysM domain
O7A_10690	COG1819	glycosyl
O7A_10695	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
O7A_10700	COG0534	Mate efflux family protein
O7A_10705	COG1366	Belongs to the anti-sigma-factor antagonist family
O7A_10710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O7A_10715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O7A_10725	COG2962	Rard protein
O7A_10740	COG2610	gluconate transmembrane transporter activity
O7A_10745	COG1942	4-Oxalocrotonate Tautomerase
O7A_10750	COG1733	regulation of RNA biosynthetic process
O7A_10755	COG0778	Nitroreductase
O7A_10760	COG0400	carboxylic ester hydrolase activity
O7A_10765	COG0346	lactoylglutathione lyase activity
O7A_10775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O7A_10780	COG0793	Belongs to the peptidase S41A family
O7A_10780	COG3409	Peptidoglycan-binding domain 1 protein
O7A_10785	COG2226	methyltransferase
O7A_10795	COG1876	peptidase activity
O7A_10800	COG0813	purine-nucleoside phosphorylase activity
O7A_10815	COG0671	phosphoesterase, PA-phosphatase related
O7A_10840	COG4479	Belongs to the UPF0346 family
O7A_10850	COG1509	lysine 2,3-aminomutase activity
O7A_10855	COG0456	acetyltransferase
O7A_10860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O7A_10865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
O7A_10870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
O7A_10875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O7A_10890	COG0456	acetyltransferase
O7A_10895	COG0463	Glycosyl transferase, family 2
O7A_10910	COG4641	Protein conserved in bacteria
O7A_10915	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
O7A_10920	COG1086	Polysaccharide biosynthesis protein
O7A_10930	COG3331	DNA recombination
O7A_10980	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
O7A_11015	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
O7A_11020	COG0756	dUTP diphosphatase activity
O7A_11025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_11055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
O7A_11055	COG1372	Participates in initiation and elongation during chromosome replication
O7A_11060	COG1780	Probably involved in ribonucleotide reductase function
O7A_11150	COG0270	DNA (cytosine-5-)-methyltransferase activity
O7A_11160	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
O7A_11165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
O7A_11190	COG3584	3D domain protein
O7A_11195	COG0587	DNA-directed DNA polymerase activity
O7A_11200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
O7A_11205	COG0358	DNA primase activity
O7A_11210	COG0305	Participates in initiation and elongation during chromosome replication
O7A_11220	COG2887	Belongs to the helicase family. UvrD subfamily
O7A_11250	COG5434	Belongs to the glycosyl hydrolase 28 family
O7A_11250	COG3420	alginic acid biosynthetic process
O7A_11255	COG4195	phage-related replication protein
O7A_11270	COG2135	peptidase activity
O7A_11275	COG1793	dna ligase
O7A_11330	COG4474	Belongs to the UPF0398 family
O7A_11340	COG1388	LysM domain
O7A_11360	COG3645	SOS response
O7A_11360	COG3646	Phage regulatory protein
O7A_11415	COG3655	Transcriptional regulator
O7A_11430	COG0582	viral genome integration into host DNA
O7A_11505	COG3655	Transcriptional regulator
O7A_11540	COG1395	domain, Protein
O7A_11555	COG0776	regulation of translation
O7A_11585	COG4373	Mu-like prophage FluMu protein gp28
O7A_11685	COG0582	viral genome integration into host DNA
O7A_11715	COG1196	nuclear chromosome segregation
O7A_11715	COG0741	lytic transglycosylase activity
O7A_11715	COG0739	heme binding
O7A_11725	COG2433	Pfam Transposase IS66
O7A_11735	COG5434	Belongs to the glycosyl hydrolase 28 family
O7A_11735	COG4632	Exopolysaccharide biosynthesis protein
O7A_11750	COG5632	N-Acetylmuramoyl-L-alanine amidase
O7A_11765	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
O7A_11770	COG0463	Glycosyl transferase, family 2
O7A_11775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_11780	COG3271	cysteine-type peptidase activity
O7A_11780	COG2274	protein secretion by the type I secretion system
O7A_11795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O7A_11825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O7A_11840	COG5444	nuclease activity
O7A_11845	COG4282	regulation of fungal-type cell wall biogenesis
O7A_11855	COG1525	nuclease
O7A_11865	COG2746	aminoglycoside 3-N-acetyltransferase activity
O7A_11890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
O7A_11895	COG1086	Polysaccharide biosynthesis protein
O7A_11900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
O7A_11905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
O7A_11910	COG1846	Transcriptional regulator
O7A_11915	COG0534	Mate efflux family protein
O7A_11925	COG4698	Protein conserved in bacteria
O7A_11930	COG2755	lipolytic protein G-D-S-L family
O7A_11935	COG1999	signal sequence binding
O7A_11950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
O7A_11955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
O7A_11960	COG1272	protein, Hemolysin III
O7A_11965	COG0204	Acyl-transferase
O7A_11970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
O7A_11975	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
O7A_11980	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
O7A_11990	COG2136	Putative SAM-dependent methyltransferase
O7A_11990	COG2521	methyltransferase
O7A_12000	COG0129	dihydroxy-acid dehydratase activity
O7A_12005	COG1413	lyase activity
O7A_12010	COG1418	mRNA catabolic process
O7A_12015	COG0386	Belongs to the glutathione peroxidase family
O7A_12020	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
O7A_12025	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
O7A_12030	COG1278	Cold shock
O7A_12050	COG0328	RNA-DNA hybrid ribonuclease activity
O7A_12055	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
O7A_12060	COG0328	RNA-DNA hybrid ribonuclease activity
O7A_12070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O7A_12090	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
O7A_12095	COG1755	Isoprenylcysteine carboxyl methyltransferase
O7A_12100	COG3424	synthase
O7A_12105	COG2233	PERMEase
O7A_12110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
O7A_12115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
O7A_12125	COG0800	Aldolase
O7A_12130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O7A_12135	COG1609	Transcriptional regulator
O7A_12140	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
O7A_12145	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_12150	COG1199	ATP-dependent helicase activity
O7A_12160	COG0116	Belongs to the methyltransferase superfamily
O7A_12170	COG4474	Belongs to the UPF0398 family
O7A_12180	COG3359	exonuclease
O7A_12185	COG1205	dead DEAH box helicase
O7A_12185	COG1111	helicase
O7A_12190	COG2190	(PTS) system
O7A_12195	COG0071	Belongs to the small heat shock protein (HSP20) family
O7A_12230	COG3331	DNA recombination
O7A_12235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O7A_12235	COG4499	WXG100 protein secretion system (Wss), protein YukC
O7A_12245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
O7A_12250	COG3935	DnaD domain protein
O7A_12255	COG0017	Asparaginyl-tRNA synthetase
O7A_12260	COG0436	Aminotransferase
O7A_12265	COG5353	protein conserved in bacteria
O7A_12275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
O7A_12275	COG1199	ATP-dependent helicase activity
O7A_12280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
O7A_12285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
O7A_12290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
O7A_12295	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
O7A_12295	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
O7A_12300	COG0617	tRNA 3'-terminal CCA addition
O7A_12305	COG0438	transferase activity, transferring glycosyl groups
O7A_12310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O7A_12315	COG1803	Methylglyoxal synthase
O7A_12320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
O7A_12325	COG1694	Mazg nucleotide pyrophosphohydrolase
O7A_12330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7A_12340	COG4347	Protein of unknown function (DUF1405)
O7A_12345	COG2010	Cytochrome c
O7A_12345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
O7A_12350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
O7A_12355	COG0723	plastoquinol--plastocyanin reductase activity
O7A_12365	COG5582	Belongs to the UPF0302 family
O7A_12370	COG0457	Tetratricopeptide repeat
O7A_12375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
O7A_12380	COG0287	Prephenate dehydrogenase
O7A_12385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
O7A_12390	COG0159	tryptophan synthase activity
O7A_12395	COG0133	tryptophan synthase activity
O7A_12400	COG0135	phosphoribosylanthranilate isomerase activity
O7A_12410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
O7A_12415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
O7A_12420	COG4401	Chorismate mutase type I
O7A_12425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
O7A_12430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
O7A_12435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
O7A_12445	COG0105	UTP biosynthetic process
O7A_12450	COG0142	geranyltranstransferase activity
O7A_12455	COG2226	methyltransferase
O7A_12460	COG0142	geranyltranstransferase activity
O7A_12470	COG0302	gtp cyclohydrolase
O7A_12475	COG0776	regulation of translation
O7A_12480	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
O7A_12495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
O7A_12500	COG1160	GTP binding
O7A_12525	COG1304	FMN binding
O7A_12530	COG0539	negative regulation of cytoplasmic translation
O7A_12535	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
O7A_12545	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
O7A_12550	COG2959	enzyme of heme biosynthesis
O7A_12555	COG3773	Cell wall hydrolase
O7A_12555	COG3409	Peptidoglycan-binding domain 1 protein
O7A_12560	COG2339	peptidase activity
O7A_12565	COG0492	ferredoxin-NADP+ reductase activity
O7A_12570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O7A_12575	COG4862	establishment of competence for transformation
O7A_12580	COG1408	metallophosphoesterase
O7A_12590	COG1388	LysM domain
O7A_12595	COG1266	CAAX protease self-immunity
O7A_12600	COG0514	ATP-dependent DNA helicase (RecQ)
O7A_12605	COG4955	Helix-turn-helix domain
O7A_12610	COG1141	Ferredoxin
O7A_12615	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
O7A_12625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
O7A_12630	COG0710	3-dehydroquinate dehydratase activity
O7A_12640	COG1595	DNA-templated transcription, initiation
O7A_12645	COG5002	protein histidine kinase activity
O7A_12650	COG0745	RESPONSE REGULATOR receiver
O7A_12655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
O7A_12660	COG1333	cytochrome c biogenesis protein
O7A_12665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_12670	COG1187	pseudouridine synthase activity
O7A_12675	COG0700	Nucleoside recognition
O7A_12680	COG2715	membrane protein required for spore maturation
O7A_12685	COG1686	Belongs to the peptidase S11 family
O7A_12695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
O7A_12700	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
O7A_12710	COG0456	acetyltransferase
O7A_12715	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
O7A_12720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
O7A_12720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
O7A_12725	COG0307	riboflavin synthase, alpha
O7A_12730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
O7A_12730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
O7A_12740	COG0681	Belongs to the peptidase S26 family
O7A_12745	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
O7A_12770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
O7A_12775	COG4086	secreted protein
O7A_12780	COG0019	diaminopimelate decarboxylase activity
O7A_12785	COG0697	spore germination
O7A_12800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O7A_12820	COG1191	sigma factor activity
O7A_12825	COG2172	sigma factor antagonist activity
O7A_12830	COG1366	Belongs to the anti-sigma-factor antagonist family
O7A_12835	COG1686	Belongs to the peptidase S11 family
O7A_12840	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
O7A_12845	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
O7A_12850	COG4974	Belongs to the 'phage' integrase family
O7A_12860	COG0735	belongs to the Fur family
O7A_12865	COG1300	Membrane
O7A_12875	COG0281	malic enzyme
O7A_12880	COG1757	Na H antiporter
O7A_12885	COG1027	Aspartate ammonia-lyase
O7A_12890	COG0252	asparaginase activity
O7A_12895	COG1396	sequence-specific DNA binding
O7A_12900	COG1379	DNA repair
O7A_12905	COG0494	nUDIX hydrolase
O7A_12915	COG0667	Aldo Keto reductase
O7A_12925	COG1073	alpha beta
O7A_12935	COG4918	Iron-sulphur cluster biosynthesis
O7A_12940	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
O7A_12940	COG0456	acetyltransferase
O7A_12945	COG2329	Antibiotic biosynthesis monooxygenase
O7A_12950	COG0456	acetyltransferase
O7A_12960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O7A_12970	COG2211	Major facilitator Superfamily
O7A_12980	COG0346	lactoylglutathione lyase activity
O7A_12985	COG1072	(Pantothenic acid kinase))
O7A_12990	COG3048	D-serine ammonia-lyase activity
O7A_12995	COG0300	oxidoreductase activity
O7A_13000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7A_13005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O7A_13010	COG4187	Peptidase family M20/M25/M40
O7A_13015	COG1902	pentaerythritol trinitrate reductase activity
O7A_13020	COG0596	Alpha beta hydrolase
O7A_13025	COG1234	tRNA 3'-trailer cleavage
O7A_13030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
O7A_13035	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
O7A_13040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O7A_13050	COG0706	membrane insertase activity
O7A_13055	COG3361	conserved protein (COG2071)
O7A_13060	COG2195	Cleaves the N-terminal amino acid of tripeptides
O7A_13065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
O7A_13070	COG0346	lactoylglutathione lyase activity
O7A_13080	COG1376	ErfK ybiS ycfS ynhG family protein
O7A_13085	COG4129	membrane
O7A_13090	COG1126	abc transporter atp-binding protein
O7A_13095	COG0765	amino acid transport
O7A_13100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7A_13110	COG1597	lipid kinase activity
O7A_13115	COG2814	Major facilitator Superfamily
O7A_13120	COG0789	Transcriptional regulator
O7A_13120	COG4978	Transcriptional regulator
O7A_13125	COG0508	dehydrogenase complex catalyzes the overall conversion of
O7A_13130	COG0022	dehydrogenase e1 component
O7A_13135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O7A_13140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O7A_13145	COG3426	butyrate kinase activity
O7A_13150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O7A_13155	COG0280	phosphate acetyltransferase
O7A_13160	COG3290	protein histidine kinase activity
O7A_13160	COG3829	transcription factor binding
O7A_13170	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
O7A_13175	COG2079	MmgE PrpD family protein
O7A_13180	COG0372	Belongs to the citrate synthase family
O7A_13185	COG1960	acyl-CoA dehydrogenase activity
O7A_13190	COG1250	3-hydroxyacyl-CoA dehydrogenase
O7A_13195	COG0183	Belongs to the thiolase family
O7A_13200	COG0584	glycerophosphoryl diester phosphodiesterase
O7A_13205	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7A_13220	COG1902	pentaerythritol trinitrate reductase activity
O7A_13230	COG0745	RESPONSE REGULATOR receiver
O7A_13240	COG0750	zinc metalloprotease
O7A_13245	COG0497	DNA recombination
O7A_13250	COG1438	arginine binding
O7A_13255	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
O7A_13260	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
O7A_13265	COG0142	geranyltranstransferase activity
O7A_13270	COG1722	exodeoxyribonuclease VII activity
O7A_13275	COG1570	exodeoxyribonuclease VII activity
O7A_13280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
O7A_13285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
O7A_13290	COG1302	Protein conserved in bacteria
O7A_13295	COG0439	Biotin carboxylase
O7A_13300	COG0511	ligase activity, forming carbon-carbon bonds
O7A_13340	COG3854	ATPases associated with a variety of cellular activities
O7A_13350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
O7A_13355	COG0006	proline dipeptidase activity
O7A_13360	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
O7A_13370	COG3872	metal-dependent enzyme
O7A_13380	COG1752	Esterase of the alpha-beta hydrolase superfamily
O7A_13385	COG1321	iron dependent repressor
O7A_13390	COG0095	Lipoate-protein ligase
O7A_13395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
O7A_13400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
O7A_13405	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
O7A_13410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
O7A_13415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
O7A_13430	COG1396	sequence-specific DNA binding
O7A_13440	COG0681	Belongs to the peptidase S26 family
O7A_13465	COG4940	Competence protein ComGF
O7A_13475	COG4970	Tfp pilus assembly protein FimT
O7A_13480	COG4537	Required for transformation and DNA binding
O7A_13485	COG1459	type II secretion system
O7A_13490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
O7A_13500	COG0598	Magnesium transport protein CorA
O7A_13505	COG1253	flavin adenine dinucleotide binding
O7A_13510	COG1366	Belongs to the anti-sigma-factor antagonist family
O7A_13520	COG1393	Belongs to the ArsC family
O7A_13530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7A_13540	COG0011	TIGRFAM Protein of
O7A_13550	COG2866	Carboxypeptidase
O7A_13555	COG1368	sulfuric ester hydrolase activity
O7A_13560	COG1940	carbohydrate kinase activity
O7A_13565	COG4483	Protein conserved in bacteria
O7A_13570	COG0457	Tetratricopeptide repeat
O7A_13570	COG0705	Rhomboid family
O7A_13580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
O7A_13585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
O7A_13590	COG0438	transferase activity, transferring glycosyl groups
O7A_13605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
O7A_13610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
O7A_13615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
O7A_13620	COG0581	inorganic phosphate transmembrane transporter activity
O7A_13625	COG0573	inorganic phosphate transmembrane transporter activity
O7A_13630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
O7A_13640	COG0477	Major facilitator Superfamily
O7A_13645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
O7A_13650	COG2839	Protein conserved in bacteria
O7A_13655	COG5521	maltodextrose utilization protein MalA
O7A_13665	COG1388	LysM domain
O7A_13670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
O7A_13675	COG4709	membrane
O7A_13680	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
O7A_13685	COG0735	belongs to the Fur family
O7A_13690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7A_13700	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
O7A_13705	COG0513	Belongs to the DEAD box helicase family
O7A_13715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
O7A_13720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
O7A_13725	COG2384	SAM-dependent methyltransferase
O7A_13730	COG2010	Cytochrome c
O7A_13735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
O7A_13740	COG0358	DNA primase activity
O7A_13745	COG1671	Belongs to the UPF0178 family
O7A_13750	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
O7A_13755	COG0517	IMP dehydrogenase activity
O7A_13760	COG0751	glycine-tRNA ligase activity
O7A_13765	COG0752	glycyl-tRNA synthetase alpha subunit
O7A_13770	COG1381	Involved in DNA repair and RecF pathway recombination
O7A_13780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
O7A_13785	COG0295	cytidine deaminase activity
O7A_13790	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
O7A_13795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
O7A_13800	COG1480	7TM receptor with intracellular HD hydrolase
O7A_13810	COG1702	phosphate starvation-inducible protein PhoH
O7A_13815	COG0561	phosphatase activity
O7A_13830	COG4864	UPF0365 protein
O7A_13835	COG1030	water channel activity
O7A_13840	COG1610	YqeY-like protein
O7A_13845	COG0828	Belongs to the bacterial ribosomal protein bS21 family
O7A_13850	COG1283	sodium-dependent phosphate transmembrane transporter activity
O7A_13855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
O7A_13860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
O7A_13865	COG2264	protein methyltransferase activity
O7A_13870	COG0484	heat shock protein binding
O7A_13875	COG0443	Heat shock 70 kDa protein
O7A_13880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
O7A_13885	COG1420	regulation of RNA biosynthetic process
O7A_13890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
O7A_13895	COG0481	GTPase activity
O7A_13905	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7A_13910	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
O7A_13915	COG0268	Binds directly to 16S ribosomal RNA
O7A_13920	COG1466	dna polymerase III delta subunit
O7A_13930	COG2333	competence protein COMEC
O7A_13930	COG0658	competence protein
O7A_13935	COG2131	deaminase
O7A_13940	COG1555	photosystem II stabilization
O7A_13940	COG1596	polysaccharide export
O7A_13945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O7A_13950	COG2226	methyltransferase
O7A_13955	COG0799	negative regulation of ribosome biogenesis
O7A_13960	COG1713	HD superfamily hydrolase involved in NAD metabolism
O7A_13965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
O7A_13970	COG1534	Rna-binding protein
O7A_13975	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
O7A_13980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
O7A_13985	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
O7A_14000	COG2755	lipolytic protein G-D-S-L family
O7A_14005	COG3409	Peptidoglycan-binding domain 1 protein
O7A_14005	COG5632	N-Acetylmuramoyl-L-alanine amidase
O7A_14010	COG0398	Pfam SNARE associated Golgi protein
O7A_14015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
O7A_14025	COG3209	COG3209 Rhs family protein
O7A_14035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
O7A_14040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
O7A_14045	COG0798	PFAM Bile acid sodium symporter
O7A_14050	COG0346	lactoylglutathione lyase activity
O7A_14055	COG0640	Transcriptional regulator
O7A_14060	COG3403	YqcI/YcgG family
O7A_14065	COG0457	Tetratricopeptide repeat
O7A_14080	COG5444	nuclease activity
O7A_14105	COG3409	Peptidoglycan-binding domain 1 protein
O7A_14105	COG5632	N-Acetylmuramoyl-L-alanine amidase
O7A_14110	COG4824	toxin secretion phage lysis holin
O7A_14140	COG3778	Protein conserved in bacteria
O7A_14145	COG3299	homolog of phage Mu protein gp47
O7A_14150	COG3628	GPW Gp25 family protein
O7A_14160	COG4193	domain, Protein
O7A_14165	COG1652	LysM domain
O7A_14170	COG5280	Phage tail tape measure protein TP901
O7A_14170	COG3953	SLT domain
O7A_14230	COG4653	Phage capsid family
O7A_14235	COG0338	D12 class N6 adenine-specific DNA methyltransferase
O7A_14245	COG2369	cell adhesion
O7A_14250	COG5518	Phage portal protein
O7A_14255	COG1783	phage Terminase large subunit
O7A_14260	COG5484	DNA packaging
O7A_14270	COG3677	Transposase
O7A_14285	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
O7A_14300	COG1484	DNA-dependent DNA replication
O7A_14305	COG3935	DnaD domain protein
O7A_14310	COG3723	Recombinational DNA repair protein, rece pathway
O7A_14315	COG5377	YqaJ viral recombinase family
O7A_14340	COG1476	TRANSCRIPTIONal
O7A_14345	COG3620	sequence-specific DNA binding
O7A_14355	COG0563	adenylate kinase activity
O7A_14360	COG2856	Zn peptidase
O7A_14375	COG3223	Belongs to the PsiE family
O7A_14380	COG0642	Histidine kinase
O7A_14380	COG5002	protein histidine kinase activity
O7A_14385	COG0745	RESPONSE REGULATOR receiver
O7A_14390	COG2311	Membrane
O7A_14400	COG0454	-acetyltransferase
O7A_14405	COG2249	NAD(P)H dehydrogenase (quinone) activity
O7A_14415	COG0730	response to heat
O7A_14420	COG0425	Belongs to the sulfur carrier protein TusA family
O7A_14425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
O7A_14425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7A_14435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
O7A_14435	COG0425	Belongs to the sulfur carrier protein TusA family
O7A_14440	COG2210	Belongs to the sulfur carrier protein TusA family
O7A_14445	COG1937	Protein conserved in bacteria
O7A_14450	COG0662	Cupin 2, conserved barrel domain protein
O7A_14465	COG4978	Transcriptional regulator
O7A_14465	COG0789	Transcriptional regulator
O7A_14470	COG2814	Major facilitator Superfamily
O7A_14475	COG0456	acetyltransferase
O7A_14480	COG1253	flavin adenine dinucleotide binding
O7A_14490	COG0697	spore germination
O7A_14495	COG0583	DNA-binding transcription factor activity
O7A_14500	COG2072	flavoprotein involved in K transport
O7A_14505	COG1230	cation diffusion facilitator family transporter
O7A_14510	COG1942	4-Oxalocrotonate Tautomerase
O7A_14515	COG0583	DNA-binding transcription factor activity
O7A_14525	COG1114	Component of the transport system for branched-chain amino acids
O7A_14530	COG1687	branched-chain amino acid
O7A_14535	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
O7A_14540	COG1522	sequence-specific DNA binding
O7A_14545	COG2732	(Barnase) inhibitor
O7A_14550	COG2124	cytochrome p450
O7A_14560	COG1335	isochorismatase
O7A_14570	COG2318	DinB family
O7A_14580	COG2070	2-Nitropropane dioxygenase
O7A_14585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
O7A_14600	COG3443	Belongs to the bacterial solute-binding protein 9 family
O7A_14605	COG1595	DNA-templated transcription, initiation
O7A_14610	COG0667	Aldo Keto reductase
O7A_14615	COG2851	Citrate transporter
O7A_14620	COG0583	DNA-binding transcription factor activity
O7A_14625	COG2828	Protein conserved in bacteria
O7A_14630	COG3409	Peptidoglycan-binding domain 1 protein
O7A_14635	COG5566	PFAM Mor transcription activator
O7A_14640	COG0596	Alpha beta hydrolase
O7A_14645	COG4991	sh3 domain protein
O7A_14650	COG4991	sh3 domain protein
O7A_14655	COG0346	lactoylglutathione lyase activity
O7A_14665	COG5577	PFAM Coat F domain
O7A_14670	COG1063	alcohol dehydrogenase
O7A_14680	COG5577	PFAM Coat F domain
O7A_14685	COG0789	Transcriptional regulator
O7A_14695	COG1064	alcohol dehydrogenase
O7A_14700	COG0693	protein deglycase activity
O7A_14705	COG1621	beta-fructofuranosidase activity
O7A_14710	COG3716	PTS system mannose fructose sorbose family IID component
O7A_14715	COG3715	PTS system
O7A_14720	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7A_14725	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7A_14730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
O7A_14730	COG3933	PFAM sigma-54 factor interaction domain-containing protein
O7A_14735	COG1113	amino acid transport
O7A_14740	COG1280	lysine exporter protein (LysE YggA)
O7A_14745	COG1378	Sugar-specific transcriptional regulator TrmB
O7A_14750	COG1595	DNA-templated transcription, initiation
O7A_14760	COG2755	lipolytic protein G-D-S-L family
O7A_14760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
O7A_14770	COG2124	cytochrome p450
O7A_14770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
O7A_14775	COG1309	transcriptional regulator
O7A_14780	COG2226	methyltransferase
O7A_14790	COG2116	formate transmembrane transporter activity
O7A_14795	COG5609	conserved protein (DUF2294)
O7A_14800	COG3383	formate dehydrogenase (NAD+) activity
O7A_14805	COG2427	Protein of unknown function (DUF1641)
O7A_14815	COG0626	cystathionine gamma-synthase activity
O7A_14820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O7A_14825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
O7A_14830	COG2226	methyltransferase
O7A_14845	COG0768	penicillin binding
O7A_14850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
O7A_14855	COG0572	uridine kinase
O7A_14875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
O7A_14880	COG3906	Belongs to the UPF0473 family
O7A_14885	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
O7A_14890	COG4472	Bacterial protein of unknown function (DUF965)
O7A_14895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
O7A_14900	COG0628	permease
O7A_14905	COG1126	abc transporter atp-binding protein
O7A_14910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7A_14915	COG0765	amino acid transport
O7A_14920	COG0765	amino acid transport
O7A_14935	COG3881	PFAM PRC-barrel domain
O7A_14940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
O7A_14945	COG0457	Tetratricopeptide repeat
O7A_14950	COG0482	sulfurtransferase activity
O7A_14955	COG1104	cysteine desulfurase activity
O7A_14960	COG1959	2 iron, 2 sulfur cluster binding
O7A_14965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
O7A_14970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
O7A_14980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
O7A_14985	COG0124	histidyl-tRNA synthetase
O7A_14995	COG3103	Sh3 type 3 domain protein
O7A_14995	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7A_14995	COG4991	sh3 domain protein
O7A_15000	COG1490	D-aminoacyl-tRNA deacylase activity
O7A_15005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
O7A_15010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
O7A_15015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
O7A_15015	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
O7A_15020	COG5416	Lipopolysaccharide assembly protein A domain
O7A_15025	COG0490	domain, Protein
O7A_15030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
O7A_15030	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
O7A_15040	COG2244	polysaccharide biosynthetic process
O7A_15045	COG2323	membrane
O7A_15055	COG1862	Preprotein translocase
O7A_15060	COG0343	queuine tRNA-ribosyltransferase activity
O7A_15065	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
O7A_15075	COG2255	four-way junction helicase activity
O7A_15080	COG0632	four-way junction helicase activity
O7A_15090	COG2814	Major facilitator Superfamily
O7A_15095	COG0673	inositol 2-dehydrogenase activity
O7A_15100	COG2112	serine threonine protein kinase
O7A_15120	COG1115	amino acid carrier protein
O7A_15125	COG0217	transcriptional regulatory protein
O7A_15135	COG1388	LysM domain
O7A_15140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
O7A_15145	COG0157	Belongs to the NadC ModD family
O7A_15150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
O7A_15155	COG1104	cysteine desulfurase activity
O7A_15160	COG1827	regulation of RNA biosynthetic process
O7A_15165	COG0077	Prephenate dehydratase
O7A_15170	COG4492	Belongs to the UPF0735 family
O7A_15175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
O7A_15180	COG3290	protein histidine kinase activity
O7A_15190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
O7A_15195	COG2868	ribosomal protein
O7A_15200	COG0261	This protein binds to 23S rRNA in the presence of protein L20
O7A_15205	COG1994	Peptidase M50
O7A_15210	COG0739	heme binding
O7A_15215	COG2894	cell division
O7A_15220	COG0850	regulation of cytokinetic process
O7A_15225	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
O7A_15230	COG1792	Involved in formation and maintenance of cell shape
O7A_15235	COG1077	Cell shape determining protein MreB Mrl
O7A_15240	COG2003	Belongs to the UPF0758 family
O7A_15245	COG0424	maF-like protein
O7A_15255	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
O7A_15260	COG0285	dihydrofolate synthase activity
O7A_15265	COG0525	valine-tRNA ligase activity
O7A_15275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O7A_15280	COG1388	LysM domain
O7A_15285	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
O7A_15290	COG0113	porphobilinogen synthase activity
O7A_15295	COG1587	Uroporphyrinogen-III synthase
O7A_15300	COG0181	hydroxymethylbilane synthase activity
O7A_15305	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
O7A_15310	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
O7A_15320	COG0218	Necessary for normal cell division and for the maintenance of normal septation
O7A_15325	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
O7A_15330	COG1067	ATP-dependent peptidase activity
O7A_15330	COG0470	DNA polymerase III
O7A_15335	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
O7A_15340	COG0544	peptidyl-prolyl cis-trans isomerase activity
O7A_15345	COG1477	protein flavinylation
O7A_15345	COG0457	Tetratricopeptide repeat
O7A_15350	COG0066	3-isopropylmalate dehydratase activity
O7A_15355	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
O7A_15360	COG0473	3-isopropylmalate dehydrogenase activity
O7A_15365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
O7A_15370	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
O7A_15375	COG0440	acetolactate synthase activity
O7A_15380	COG0028	Belongs to the TPP enzyme family
O7A_15390	COG0454	-acetyltransferase
O7A_15400	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
O7A_15410	COG0622	Phosphoesterase
O7A_15415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
O7A_15420	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
O7A_15425	COG5401	PFAM Sporulation and spore germination
O7A_15430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
O7A_15435	COG1846	Transcriptional regulator
O7A_15440	COG2197	response regulator
O7A_15445	COG0824	Thioesterase
O7A_15450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
O7A_15455	COG1053	succinate dehydrogenase
O7A_15460	COG2009	succinate dehydrogenase
O7A_15470	COG1719	4-vinyl reductase, 4VR
O7A_15475	COG0527	aspartate kinase activity
O7A_15480	COG0322	excinuclease ABC activity
O7A_15485	COG3118	belongs to the thioredoxin family
O7A_15490	COG3534	alpha-L-arabinofuranosidase
O7A_15495	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
O7A_15500	COG2086	electron transfer activity
O7A_15505	COG1024	Enoyl-CoA hydratase
O7A_15510	COG1309	transcriptional regulator
O7A_15515	COG0318	PFAM AMP-dependent synthetase and ligase
O7A_15520	COG3766	membrane
O7A_15525	COG1193	negative regulation of DNA recombination
O7A_15530	COG1796	DNA polymerase
O7A_15530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
O7A_15535	COG1286	toxin biosynthetic process
O7A_15540	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
O7A_15545	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
O7A_15550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O7A_15550	COG0072	phenylalanine-tRNA ligase activity
O7A_15555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
O7A_15565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
O7A_15575	COG3835	regulator
O7A_15580	COG0277	FAD linked oxidase domain protein
O7A_15585	COG0247	lactate metabolic process
O7A_15590	COG0346	lactoylglutathione lyase activity
O7A_15600	COG1966	Carbon starvation protein
O7A_15605	COG3534	alpha-L-arabinofuranosidase
O7A_15610	COG0395	ABC-type sugar transport system, permease component
O7A_15615	COG1175	transmembrane transport
O7A_15620	COG1653	transport
O7A_15625	COG0371	Dehydrogenase
O7A_15630	COG0647	UMP catabolic process
O7A_15635	COG0235	Class ii aldolase
O7A_15640	COG1069	ribulokinase activity
O7A_15645	COG2160	L-arabinose isomerase activity
O7A_15650	COG3507	Belongs to the glycosyl hydrolase 43 family
O7A_15655	COG1363	Peptidase, m42
O7A_15665	COG3326	Membrane
O7A_15670	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
O7A_15675	COG0291	Belongs to the bacterial ribosomal protein bL35 family
O7A_15680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
O7A_15690	COG1346	cytolysis
O7A_15695	COG1380	Effector of murein hydrolase LrgA
O7A_15700	COG3279	Response regulator of the LytR AlgR family
O7A_15705	COG3275	phosphorelay sensor kinase activity
O7A_15715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
O7A_15725	COG0398	Pfam SNARE associated Golgi protein
O7A_15730	COG1484	DNA-dependent DNA replication
O7A_15735	COG3611	Membrane attachment protein
O7A_15740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
O7A_15745	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
O7A_15750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
O7A_15755	COG1733	regulation of RNA biosynthetic process
O7A_15760	COG2814	Major facilitator Superfamily
O7A_15765	COG0656	L-ascorbic acid biosynthetic process
O7A_15770	COG0237	dephospho-CoA kinase activity
O7A_15785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
O7A_15790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O7A_15790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O7A_15795	COG5002	protein histidine kinase activity
O7A_15800	COG0745	RESPONSE REGULATOR receiver
O7A_15805	COG0039	L-malate dehydrogenase activity
O7A_15810	COG0538	isocitrate dehydrogenase activity
O7A_15815	COG0372	Belongs to the citrate synthase family
O7A_15820	COG2707	UPF0756 membrane protein
O7A_15825	COG0628	permease
O7A_15830	COG3030	protein affecting phage T7 exclusion by the F plasmid
O7A_15835	COG0469	pyruvate kinase activity
O7A_15840	COG0205	6-phosphofructokinase activity
O7A_15845	COG0825	malonyl-CoA metabolic process
O7A_15850	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
O7A_15855	COG0281	malic enzyme
O7A_15860	COG0587	DNA-directed DNA polymerase activity
O7A_15880	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
O7A_15890	COG4109	DRTGG domain
O7A_15900	COG0730	response to heat
O7A_15905	COG1473	amidohydrolase
O7A_15910	COG0196	riboflavin kinase activity
O7A_15915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7A_15920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
O7A_15925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7A_15930	COG1126	abc transporter atp-binding protein
O7A_15935	COG0765	amino acid transport
O7A_15940	COG0765	amino acid transport
O7A_15945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7A_15950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7A_15955	COG0454	-acetyltransferase
O7A_15960	COG0583	DNA-binding transcription factor activity
O7A_15965	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
O7A_15970	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_15980	COG0165	Argininosuccinate lyase
O7A_15985	COG0137	argininosuccinate synthase activity
O7A_15990	COG0521	Mo-molybdopterin cofactor biosynthetic process
O7A_15995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
O7A_16000	COG0827	DNA restriction-modification system
O7A_16005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
O7A_16010	COG3874	Sporulation protein YtfJ
O7A_16020	COG1714	RDD family
O7A_16025	COG0616	signal peptide processing
O7A_16030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
O7A_16035	COG1574	metal-dependent hydrolase with the TIM-barrel fold
O7A_16040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
O7A_16050	COG0301	tRNA thio-modification
O7A_16055	COG1104	cysteine desulfurase activity
O7A_16060	COG1114	Component of the transport system for branched-chain amino acids
O7A_16065	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
O7A_16070	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
O7A_16075	COG1309	transcriptional regulator
O7A_16080	COG1956	GAF domain-containing protein
O7A_16085	COG2199	diguanylate cyclase activity
O7A_16085	COG2203	Gaf domain
O7A_16090	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
O7A_16100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
O7A_16105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
O7A_16110	COG0454	-acetyltransferase
O7A_16115	COG0517	IMP dehydrogenase activity
O7A_16120	COG0123	including yeast histone deacetylase and acetoin utilization protein
O7A_16125	COG1360	Flagellar Motor Protein
O7A_16130	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
O7A_16135	COG1609	Transcriptional regulator
O7A_16140	COG1605	Chorismate mutase
O7A_16140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
O7A_16145	COG3118	belongs to the thioredoxin family
O7A_16150	COG4980	gas vesicle protein
O7A_16155	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
O7A_16160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
O7A_16165	COG1674	ftsk spoiiie
O7A_16170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O7A_16175	COG4848	Belongs to the UPF0354 family
O7A_16180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_16190	COG1363	Peptidase, m42
O7A_16195	COG5584	Small secreted protein
O7A_16200	COG0281	malic enzyme
O7A_16205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7A_16210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
O7A_16220	COG0510	thiamine kinase activity
O7A_16225	COG1523	belongs to the glycosyl hydrolase 13 family
O7A_16230	COG1597	lipid kinase activity
O7A_16240	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
O7A_16245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O7A_16250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O7A_16255	COG2252	PERMEase
O7A_16260	COG4473	ABC transporter
O7A_16265	COG1131	(ABC) transporter
O7A_16270	COG1349	DNA-binding transcription factor activity
O7A_16275	COG1187	pseudouridine synthase activity
O7A_16280	COG2244	polysaccharide biosynthetic process
O7A_16285	COG2081	HI0933 family
O7A_16290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
O7A_16300	COG5578	integral membrane protein
O7A_16305	COG0673	inositol 2-dehydrogenase activity
O7A_16310	COG1653	transport
O7A_16315	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
O7A_16320	COG4209	transmembrane transport
O7A_16325	COG2207	Transcriptional regulator
O7A_16330	COG1653	transport
O7A_16335	COG0395	ABC-type sugar transport system, permease component
O7A_16340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7A_16345	COG2124	cytochrome p450
O7A_16350	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
O7A_16355	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
O7A_16360	COG0156	8-amino-7-oxononanoate synthase activity
O7A_16365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O7A_16370	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
O7A_16375	COG1073	alpha beta
O7A_16400	COG1486	melibiose metabolic process
O7A_16405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
O7A_16410	COG0495	leucyl-tRNA aminoacylation
O7A_16420	COG2202	Pas domain
O7A_16420	COG1366	Belongs to the anti-sigma-factor antagonist family
O7A_16425	COG2814	Major facilitator Superfamily
O7A_16430	COG2433	Pfam Transposase IS66
O7A_16435	COG0577	efflux transmembrane transporter activity
O7A_16440	COG1136	(ABC) transporter
O7A_16445	COG2205	protein histidine kinase activity
O7A_16450	COG0745	RESPONSE REGULATOR receiver
O7A_16455	COG0577	efflux transmembrane transporter activity
O7A_16460	COG1136	(ABC) transporter
O7A_16475	COG1131	(ABC) transporter
O7A_16480	COG1725	Transcriptional regulator
O7A_16495	COG1242	4 iron, 4 sulfur cluster binding
O7A_16500	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
O7A_16510	COG2267	carboxylic ester hydrolase activity
O7A_16515	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
O7A_16520	COG1113	amino acid transport
O7A_16525	COG0367	asparagine synthase
O7A_16530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
O7A_16535	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
O7A_16545	COG1506	peptidase
O7A_16550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
O7A_16555	COG1116	anion transmembrane transporter activity
O7A_16560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
O7A_16565	COG0494	nUDIX hydrolase
O7A_16570	COG4824	toxin secretion phage lysis holin
O7A_16575	COG0783	Belongs to the Dps family
O7A_16590	COG1854	S-ribosylhomocysteine lyase activity
O7A_16595	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
O7A_16600	COG0288	reversible hydration of carbon dioxide
O7A_16605	COG0254	rRNA binding
O7A_16610	COG1271	oxidase subunit
O7A_16615	COG1294	oxidase, subunit
O7A_16625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
O7A_16630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
O7A_16630	COG1321	iron dependent repressor
O7A_16635	COG1121	(ABC) transporter
O7A_16640	COG0803	Belongs to the bacterial solute-binding protein 9 family
O7A_16645	COG4948	Mandelate Racemase Muconate Lactonizing
O7A_16650	COG0318	PFAM AMP-dependent synthetase and ligase
O7A_16655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
O7A_16660	COG0596	Alpha beta hydrolase
O7A_16665	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
O7A_16670	COG1169	isochorismate synthase
O7A_16675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O7A_16680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
O7A_16685	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
O7A_16690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O7A_16695	COG0438	transferase activity, transferring glycosyl groups
O7A_16705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O7A_16710	COG0438	transferase activity, transferring glycosyl groups
O7A_16715	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O7A_16720	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
O7A_16725	COG0058	SHG alpha-glucan phosphorylase activity
O7A_16730	COG0297	glycogen (starch) synthase activity
O7A_16735	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
O7A_16740	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
O7A_16745	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
O7A_16875	COG3859	Proton-coupled thiamine transporter YuaJ
O7A_16880	COG1247	-acetyltransferase
O7A_16885	COG2268	Band 7 protein
O7A_16890	COG1585	Membrane protein implicated in regulation of membrane protease activity
O7A_16895	COG2318	DinB family
O7A_16905	COG1454	alcohol dehydrogenase
O7A_16915	COG1510	regulation of RNA biosynthetic process
O7A_16925	COG0569	domain protein
O7A_16930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
O7A_16935	COG4682	membrane
O7A_16940	COG1705	Flagellar rod assembly protein muramidase FlgJ
O7A_16945	COG0477	Major facilitator Superfamily
O7A_16950	COG5553	Cysteine dioxygenase type I
O7A_16960	COG1968	undecaprenyl-diphosphatase activity
O7A_16965	COG0628	permease
O7A_16970	COG0673	inositol 2-dehydrogenase activity
O7A_16975	COG4806	L-rhamnose isomerase
O7A_16980	COG3254	rhamnose metabolic process
O7A_16985	COG1070	Carbohydrate kinase
O7A_16990	COG1349	DNA-binding transcription factor activity
O7A_16995	COG3347	Dehydrogenase
O7A_16995	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_17000	COG0840	transmembrane signaling receptor activity
O7A_17005	COG0840	transmembrane signaling receptor activity
O7A_17010	COG0840	transmembrane signaling receptor activity
O7A_17015	COG0840	transmembrane signaling receptor activity
O7A_17030	COG0432	Pfam Uncharacterised protein family UPF0047
O7A_17035	COG0366	Alpha amylase catalytic
O7A_17040	COG1253	flavin adenine dinucleotide binding
O7A_17045	COG2738	Putative neutral zinc metallopeptidase
O7A_17060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
O7A_17075	COG0166	Belongs to the GPI family
O7A_17080	COG1979	alcohol dehydrogenase
O7A_17085	COG1979	alcohol dehydrogenase
O7A_17090	COG2155	Conserved Protein
O7A_17095	COG1098	S1 RNA binding domain
O7A_17100	COG0436	Aminotransferase
O7A_17105	COG1522	sequence-specific DNA binding
O7A_17110	COG2267	carboxylic ester hydrolase activity
O7A_17120	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
O7A_17125	COG2205	protein histidine kinase activity
O7A_17135	COG5018	Exonuclease
O7A_17145	COG2814	Major facilitator Superfamily
O7A_17150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O7A_17155	COG3011	Protein conserved in bacteria
O7A_17165	COG3290	protein histidine kinase activity
O7A_17170	COG4565	transcriptional regulatory protein
O7A_17195	COG3493	citrate carrier protein
O7A_17205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
O7A_17205	COG2111	Na H antiporter
O7A_17210	COG2111	Na H antiporter
O7A_17215	COG1006	Multisubunit Na H antiporter MnhC subunit
O7A_17220	COG0651	ATP synthesis coupled electron transport
O7A_17225	COG1863	multisubunit Na H antiporter MnhE subunit
O7A_17230	COG2212	antiporter activity
O7A_17235	COG1320	monovalent cation:proton antiporter activity
O7A_17240	COG2050	protein possibly involved in aromatic compounds catabolism
O7A_17245	COG2197	response regulator
O7A_17260	COG0142	geranyltranstransferase activity
O7A_17275	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
O7A_17280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
O7A_17285	COG1335	isochorismatase
O7A_17290	COG5506	Protein of unknown function (DUF1694)
O7A_17305	COG0628	permease
O7A_17320	COG1418	mRNA catabolic process
O7A_17325	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_17335	COG1511	domain protein
O7A_17340	COG1674	ftsk spoiiie
O7A_17340	COG0433	COG0433 Predicted ATPase
O7A_17345	COG4499	WXG100 protein secretion system (Wss), protein YukC
O7A_17350	COG5417	Belongs to the EsaB family
O7A_17355	COG4842	Belongs to the WXG100 family
O7A_17360	COG2508	Transcriptional regulator
O7A_17360	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
O7A_17365	COG0686	Belongs to the AlaDH PNT family
O7A_17370	COG5634	Uncharacterized conserved protein (DUF2278)
O7A_17375	COG3251	PFAM MbtH domain protein
O7A_17380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_17385	COG3433	isochorismatase activity
O7A_17385	COG1535	isochorismatase
O7A_17390	COG1021	2,3-dihydroxybenzoate-AMP ligase
O7A_17395	COG1169	isochorismate synthase
O7A_17400	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_17405	COG2819	hydrolase of the alpha beta superfamily
O7A_17410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
O7A_17415	COG1268	BioY protein
O7A_17420	COG2056	Na+-H+ antiporter family
O7A_17425	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
O7A_17430	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
O7A_17435	COG3584	3D domain protein
O7A_17450	COG1252	NADH dehydrogenase
O7A_17455	COG0492	ferredoxin-NADP+ reductase activity
O7A_17465	COG0516	GMP reductase activity
O7A_17470	COG2808	Putative FMN-binding domain
O7A_17475	COG0456	acetyltransferase
O7A_17480	COG0316	Belongs to the HesB IscA family
O7A_17485	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
O7A_17490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O7A_17495	COG4844	belongs to the
O7A_17500	COG1252	NADH dehydrogenase
O7A_17505	COG4837	Protein of unknown function (DUF1462)
O7A_17510	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
O7A_17515	COG1506	peptidase
O7A_17515	COG0823	Involved in the tonB-independent uptake of proteins
O7A_17515	COG4946	Tricorn protease homolog
O7A_17520	COG0083	homoserine kinase activity
O7A_17525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
O7A_17530	COG0460	homoserine dehydrogenase
O7A_17535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O7A_17540	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
O7A_17545	COG0647	UMP catabolic process
O7A_17550	COG2445	Protein of unknown function DUF86
O7A_17555	COG4470	Protein conserved in bacteria
O7A_17565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
O7A_17570	COG0739	heme binding
O7A_17580	COG3377	Domain of unknown function (DUF1805)
O7A_17585	COG0737	Belongs to the 5'-nucleotidase family
O7A_17590	COG0730	response to heat
O7A_17595	COG1801	Protein of unknown function DUF72
O7A_17605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
O7A_17610	COG2508	Transcriptional regulator
O7A_17615	COG2233	PERMEase
O7A_17620	COG2233	PERMEase
O7A_17625	COG3648	Uricase
O7A_17625	COG3195	allantoin biosynthetic process
O7A_17630	COG2351	hydroxyisourate hydrolase activity
O7A_17640	COG2080	2 iron, 2 sulfur cluster binding
O7A_17645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
O7A_17650	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
O7A_17655	COG2068	MobA-Related Protein
O7A_17660	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
O7A_17665	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
O7A_17670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O7A_17680	COG2356	endonuclease I
O7A_17685	COG3842	ATPase activity
O7A_17690	COG2188	Transcriptional regulator
O7A_17695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O7A_17700	COG0395	ABC-type sugar transport system, permease component
O7A_17705	COG1175	transmembrane transport
O7A_17710	COG1653	transport
O7A_17715	COG2222	sugar isomerase
O7A_17720	COG0322	excinuclease ABC activity
O7A_17725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O7A_17740	COG0346	lactoylglutathione lyase activity
O7A_17745	COG0640	Transcriptional regulator
O7A_17750	COG0719	Fe-S assembly protein
O7A_17755	COG0822	iron-sulfur transferase activity
O7A_17760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
O7A_17765	COG0719	Fe-S assembly protein
O7A_17770	COG0396	ATPase activity
O7A_17780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
O7A_17785	COG1464	Belongs to the NlpA lipoprotein family
O7A_17790	COG2011	ABC-type metal ion transport system permease component
O7A_17795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
O7A_17805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O7A_17810	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
O7A_17820	COG0509	glycine decarboxylation via glycine cleavage system
O7A_17825	COG1393	Belongs to the ArsC family
O7A_17830	COG1960	acyl-CoA dehydrogenase activity
O7A_17835	COG0183	Belongs to the thiolase family
O7A_17840	COG1024	Enoyl-CoA hydratase
O7A_17840	COG1250	3-hydroxyacyl-CoA dehydrogenase
O7A_17850	COG0506	proline dehydrogenase activity
O7A_17860	COG5577	PFAM Coat F domain
O7A_17865	COG1846	Transcriptional regulator
O7A_17870	COG0477	Major facilitator Superfamily
O7A_17875	COG1942	4-Oxalocrotonate Tautomerase
O7A_17880	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_17885	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_17890	COG0583	DNA-binding transcription factor activity
O7A_17900	COG1120	ATPase activity
O7A_17920	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_17925	COG0783	Belongs to the Dps family
O7A_17930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O7A_17935	COG0745	RESPONSE REGULATOR receiver
O7A_17940	COG2770	Histidine kinase
O7A_17940	COG2205	protein histidine kinase activity
O7A_17950	COG1309	transcriptional regulator
O7A_17955	COG0114	fumarate hydratase activity
O7A_17965	COG0697	spore germination
O7A_17970	COG0814	amino acid
O7A_17980	COG2197	response regulator
O7A_17985	COG4585	Histidine kinase
O7A_17990	COG4758	membrane
O7A_17995	COG3595	metallopeptidase activity
O7A_18000	COG1842	Phage shock protein A
O7A_18005	COG4758	membrane
O7A_18010	COG2814	Major facilitator Superfamily
O7A_18015	COG2096	Adenosyltransferase
O7A_18020	COG1120	ATPase activity
O7A_18025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7A_18030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7A_18040	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_18045	COG3386	PFAM SMP-30 Gluconolaconase
O7A_18050	COG2205	protein histidine kinase activity
O7A_18055	COG0745	RESPONSE REGULATOR receiver
O7A_18065	COG1191	sigma factor activity
O7A_18075	COG2140	Oxalate decarboxylase
O7A_18085	COG0577	efflux transmembrane transporter activity
O7A_18090	COG1136	(ABC) transporter
O7A_18095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
O7A_18100	COG1120	ATPase activity
O7A_18105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7A_18110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O7A_18115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7A_18125	COG0531	amino acid
O7A_18135	COG1988	membrane-bound metal-dependent
O7A_18140	COG1368	sulfuric ester hydrolase activity
O7A_18145	COG1910	domain protein
O7A_18150	COG0725	ABC transporter, periplasmic molybdate-binding protein
O7A_18155	COG4149	molybdate abc transporter
O7A_18160	COG0656	L-ascorbic acid biosynthetic process
O7A_18170	COG0025	NhaP-type Na H and K H
O7A_18175	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
O7A_18180	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
O7A_18185	COG3973	AAA domain
O7A_18190	COG2860	membrane
O7A_18195	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
O7A_18200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
O7A_18205	COG2217	Heavy metal translocating P-type atpase
O7A_18210	COG2217	Heavy metal translocating P-type atpase
O7A_18215	COG2608	mercury ion transmembrane transporter activity
O7A_18220	COG1937	Protein conserved in bacteria
O7A_18225	COG0673	inositol 2-dehydrogenase activity
O7A_18230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
O7A_18235	COG1289	transmembrane transporter activity
O7A_18245	COG2076	Multidrug Resistance protein
O7A_18250	COG1309	transcriptional regulator
O7A_18255	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_18260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
O7A_18265	COG0557	exoribonuclease II activity
O7A_18270	COG1647	Serine aminopeptidase, S33
O7A_18275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
O7A_18280	COG0596	Alpha beta hydrolase
O7A_18285	COG1476	TRANSCRIPTIONal
O7A_18290	COG1396	sequence-specific DNA binding
O7A_18295	COG1396	sequence-specific DNA binding
O7A_18300	COG1733	regulation of RNA biosynthetic process
O7A_18305	COG0840	transmembrane signaling receptor activity
O7A_18310	COG1174	glycine betaine transport
O7A_18315	COG1732	Glycine betaine
O7A_18320	COG1174	glycine betaine transport
O7A_18325	COG1125	glycine betaine transport
O7A_18325	COG0517	IMP dehydrogenase activity
O7A_18330	COG1510	regulation of RNA biosynthetic process
O7A_18350	COG5658	integral membrane protein
O7A_18355	COG0640	Transcriptional regulator
O7A_18360	COG1174	glycine betaine transport
O7A_18365	COG1732	Glycine betaine
O7A_18370	COG1174	glycine betaine transport
O7A_18375	COG0517	IMP dehydrogenase activity
O7A_18375	COG1125	glycine betaine transport
O7A_18380	COG1510	regulation of RNA biosynthetic process
O7A_18385	COG2095	MarC family integral membrane protein
O7A_18395	COG3064	Membrane
O7A_18400	COG4640	response to antibiotic
O7A_18405	COG0456	acetyltransferase
O7A_18410	COG0148	phosphopyruvate hydratase activity
O7A_18415	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
O7A_18420	COG0149	triose-phosphate isomerase activity
O7A_18425	COG0126	phosphoglycerate kinase activity
O7A_18435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
O7A_18440	COG2390	Transcriptional regulator
O7A_18445	COG2814	Major facilitator Superfamily
O7A_18450	COG1609	Transcriptional regulator
O7A_18455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7A_18460	COG0583	DNA-binding transcription factor activity
O7A_18465	COG0697	spore germination
O7A_18470	COG1113	amino acid transport
O7A_18475	COG3858	chitin binding
O7A_18480	COG1556	Lactate utilization protein
O7A_18485	COG1139	Iron-sulfur cluster binding protein
O7A_18490	COG0247	lactate metabolic process
O7A_18495	COG2197	response regulator
O7A_18500	COG4585	Histidine kinase
O7A_18505	COG0842	Transport permease protein
O7A_18510	COG1131	(ABC) transporter
O7A_18515	COG0596	Alpha beta hydrolase
O7A_18520	COG2208	phosphoserine phosphatase activity
O7A_18525	COG3867	Arabinogalactan endo-beta-1,4-galactanase
O7A_18530	COG1874	Beta-galactosidase
O7A_18535	COG3833	ABC-type maltose transport systems, permease component
O7A_18540	COG1175	transmembrane transport
O7A_18545	COG2182	Extracellular solute-binding protein
O7A_18550	COG1609	Transcriptional regulator
O7A_18555	COG2186	Transcriptional regulator
O7A_18560	COG1620	l-lactate permease
O7A_18565	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
O7A_18575	COG5039	Polysaccharide pyruvyl transferase
O7A_18580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O7A_18585	COG0110	maltose O-acetyltransferase activity
O7A_18590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
O7A_18595	COG2244	polysaccharide biosynthetic process
O7A_18600	COG1216	Glycosyl transferase, family 2
O7A_18605	COG5039	Polysaccharide pyruvyl transferase
O7A_18610	COG1216	Glycosyl transferase, family 2
O7A_18620	COG0438	transferase activity, transferring glycosyl groups
O7A_18625	COG1215	transferase activity, transferring glycosyl groups
O7A_18630	COG0438	transferase activity, transferring glycosyl groups
O7A_18635	COG1086	Polysaccharide biosynthesis protein
O7A_18640	COG0489	protein tyrosine kinase activity
O7A_18645	COG3944	biosynthesis protein
O7A_18650	COG1396	sequence-specific DNA binding
O7A_18655	COG2272	Belongs to the type-B carboxylesterase lipase family
O7A_18665	COG3479	Phenolic acid decarboxylase
O7A_18675	COG1794	racemase activity, acting on amino acids and derivatives
O7A_18680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O7A_18685	COG1621	beta-fructofuranosidase activity
O7A_18690	COG1621	beta-fructofuranosidase activity
O7A_18695	COG0531	amino acid
O7A_18700	COG1309	transcriptional regulator
O7A_18705	COG2076	Multidrug Resistance protein
O7A_18710	COG2076	Multidrug Resistance protein
O7A_18720	COG0277	FAD linked oxidase domain protein
O7A_18725	COG3621	Patatin-like phospholipase
O7A_18735	COG0740	serine-type endopeptidase activity
O7A_18740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
O7A_18745	COG0366	Alpha amylase catalytic
O7A_18750	COG1554	hydrolase, family 65, central catalytic
O7A_18755	COG5521	maltodextrose utilization protein MalA
O7A_18760	COG3833	ABC-type maltose transport systems, permease component
O7A_18765	COG1175	transmembrane transport
O7A_18770	COG2182	Extracellular solute-binding protein
O7A_18775	COG0366	Alpha amylase catalytic
O7A_18780	COG1609	Transcriptional regulator
O7A_18785	COG1611	Belongs to the LOG family
O7A_18790	COG1694	Mazg nucleotide pyrophosphohydrolase
O7A_18795	COG0659	secondary active sulfate transmembrane transporter activity
O7A_18800	COG0288	reversible hydration of carbon dioxide
O7A_18805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
O7A_18810	COG0577	efflux transmembrane transporter activity
O7A_18815	COG1136	(ABC) transporter
O7A_18820	COG5002	protein histidine kinase activity
O7A_18825	COG0745	RESPONSE REGULATOR receiver
O7A_18835	COG2162	N-hydroxyarylamine O-acetyltransferase activity
O7A_18840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7A_18845	COG1481	regulation of sporulation
O7A_18850	COG0391	Required for morphogenesis under gluconeogenic growth conditions
O7A_18855	COG1660	Displays ATPase and GTPase activities
O7A_18860	COG1051	belongs to the nudix hydrolase family
O7A_18865	COG0492	ferredoxin-NADP+ reductase activity
O7A_18870	COG3883	PFAM NLP P60 protein
O7A_18870	COG0791	NLP P60 protein
O7A_18875	COG0457	Tetratricopeptide repeat
O7A_18880	COG1132	(ABC) transporter
O7A_18900	COG0140	phosphoribosyl-ATP diphosphatase activity
O7A_18900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
O7A_18905	COG0107	imidazoleglycerol-phosphate synthase activity
O7A_18910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
O7A_18915	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
O7A_18920	COG0131	Imidazoleglycerol-phosphate dehydratase
O7A_18925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
O7A_18930	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
O7A_18935	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
O7A_18940	COG4990	cell redox homeostasis
O7A_18945	COG5297	Belongs to the glycosyl hydrolase family 6
O7A_18950	COG0110	maltose O-acetyltransferase activity
O7A_18955	COG0546	phosphoglycolate phosphatase activity
O7A_18960	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
O7A_18965	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
O7A_18970	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
O7A_18975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
O7A_18980	COG0363	glucosamine-6-phosphate deaminase activity
O7A_18990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
O7A_18995	COG1846	Transcriptional regulator
O7A_19000	COG2124	cytochrome p450
O7A_19010	COG1846	Transcriptional regulator
O7A_19015	COG2814	Major facilitator Superfamily
O7A_19020	COG1950	PFAM Membrane protein of
O7A_19025	COG1983	PspC domain protein
O7A_19030	COG3595	metallopeptidase activity
O7A_19045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O7A_19050	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
O7A_19055	COG0556	nucleotide-excision repair
O7A_19060	COG4897	Protein conserved in bacteria
O7A_19065	COG3848	Pyruvate phosphate dikinase
O7A_19065	COG0574	Belongs to the PEP-utilizing enzyme family
O7A_19070	COG1309	transcriptional regulator
O7A_19075	COG2814	Major facilitator Superfamily
O7A_19080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O7A_19090	COG0793	Belongs to the peptidase S41A family
O7A_19090	COG3409	Peptidoglycan-binding domain 1 protein
O7A_19095	COG2177	Part of the ABC transporter FtsEX involved in
O7A_19100	COG2884	Cell division ATP-binding protein ftsE
O7A_19105	COG2010	Cytochrome c
O7A_19110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7A_19115	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
O7A_19120	COG0653	protein targeting
O7A_19125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
O7A_19140	COG1516	flagellar protein fliS
O7A_19145	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
O7A_19150	COG1334	flagellar protein FlaG
O7A_19155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O7A_19160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
O7A_19165	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
O7A_19175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O7A_19180	COG1256	bacterial-type flagellum assembly
O7A_19180	COG4786	Flagellar basal body rod
O7A_19185	COG3418	PFAM FlgN family protein
O7A_19190	COG2747	anti-sigma28 factor FlgM
O7A_19200	COG1040	competence protein
O7A_19210	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
O7A_19215	COG1307	EDD domain protein, DegV family
O7A_19220	COG2197	response regulator
O7A_19225	COG4585	Histidine kinase
O7A_19230	COG1739	Uncharacterized protein family UPF0029
O7A_19235	COG1316	TRANSCRIPTIONal
O7A_19240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
O7A_19245	COG0438	transferase activity, transferring glycosyl groups
O7A_19250	COG1215	transferase activity, transferring glycosyl groups
O7A_19255	COG3206	protein involved in exopolysaccharide biosynthesis
O7A_19260	COG3307	-O-antigen
O7A_19265	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
O7A_19270	COG0297	glycogen (starch) synthase activity
O7A_19270	COG0438	transferase activity, transferring glycosyl groups
O7A_19275	COG2244	polysaccharide biosynthetic process
O7A_19285	COG2247	cell wall binding repeat
O7A_19285	COG0860	N-Acetylmuramoyl-L-alanine amidase
O7A_19290	COG2247	cell wall binding repeat
O7A_19290	COG2385	sporulation resulting in formation of a cellular spore
O7A_19300	COG1316	TRANSCRIPTIONal
O7A_19305	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
O7A_19310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
O7A_19315	COG1215	transferase activity, transferring glycosyl groups
O7A_19315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O7A_19320	COG0463	Glycosyl transferase, family 2
O7A_19335	COG1134	teichoic acid transport
O7A_19340	COG1682	transport, permease protein
O7A_19345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O7A_19350	COG0438	transferase activity, transferring glycosyl groups
O7A_19355	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
O7A_19360	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
O7A_19365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O7A_19375	COG4193	domain, Protein
O7A_19380	COG1482	cell wall glycoprotein biosynthetic process
O7A_19395	COG0814	amino acid
O7A_19405	COG2814	Major facilitator Superfamily
O7A_19410	COG1316	TRANSCRIPTIONal
O7A_19415	COG0561	phosphatase activity
O7A_19420	COG0791	NLP P60 protein
O7A_19430	COG2843	Capsule synthesis protein
O7A_19440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
O7A_19445	COG1609	Transcriptional regulator
O7A_19450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O7A_19455	COG1869	D-ribose catabolic process
O7A_19460	COG1129	ABC transporter
O7A_19465	COG1172	Belongs to the binding-protein-dependent transport system permease family
O7A_19470	COG1879	ABC-type sugar transport system periplasmic component
O7A_19475	COG3103	Sh3 type 3 domain protein
O7A_19485	COG2249	NAD(P)H dehydrogenase (quinone) activity
O7A_19490	COG3527	Alpha-acetolactate decarboxylase
O7A_19495	COG0028	Belongs to the TPP enzyme family
O7A_19500	COG0583	DNA-binding transcription factor activity
O7A_19505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
O7A_19520	COG5337	Spore coat protein CotH
O7A_19530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
O7A_19540	COG0405	Gamma-glutamyltransferase
O7A_19545	COG1522	sequence-specific DNA binding
O7A_19550	COG2059	Chromate
O7A_19555	COG2059	Chromate
O7A_19565	COG0655	NAD(P)H dehydrogenase (quinone) activity
O7A_19570	COG0583	DNA-binding transcription factor activity
O7A_19575	COG1515	deoxyribonuclease V activity
O7A_19580	COG2849	repeat protein
O7A_19585	COG5444	nuclease activity
O7A_19600	COG3878	Protein conserved in bacteria
O7A_19605	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
O7A_19610	COG4464	protein tyrosine phosphatase activity
O7A_19615	COG0489	protein tyrosine kinase activity
O7A_19620	COG3944	biosynthesis protein
O7A_19630	COG4715	Zinc finger, swim domain protein
O7A_19635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
O7A_19640	COG0561	phosphatase activity
O7A_19645	COG1349	DNA-binding transcription factor activity
O7A_19650	COG0629	single-stranded DNA binding
O7A_19665	COG3764	Sortase (surface protein transpeptidase)
O7A_19670	COG2972	Histidine kinase
O7A_19670	COG0745	RESPONSE REGULATOR receiver
O7A_19675	COG1970	mechanosensitive ion channel activity
O7A_19680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
O7A_19685	COG0457	Tetratricopeptide repeat
O7A_19690	COG4786	Flagellar basal body rod
O7A_19695	COG4786	Flagellar basal body rod
O7A_19700	COG1077	Cell shape determining protein MreB Mrl
O7A_19705	COG1609	Transcriptional regulator
O7A_19710	COG1846	Transcriptional regulator
O7A_19715	COG2814	Major facilitator Superfamily
O7A_19720	COG3420	alginic acid biosynthetic process
O7A_19725	COG1953	Uracil, thiamine, allantoin
O7A_19730	COG0477	Major facilitator Superfamily
O7A_19735	COG1335	isochorismatase
O7A_19745	COG0004	ammonium transporteR
O7A_19750	COG0347	Belongs to the P(II) protein family
O7A_19755	COG0671	phosphoesterase, PA-phosphatase related
O7A_19765	COG0739	heme binding
O7A_19770	COG1247	-acetyltransferase
O7A_19790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O7A_19795	COG0789	Transcriptional regulator
O7A_19805	COG2910	NAD(P)H-binding
O7A_19810	COG1959	2 iron, 2 sulfur cluster binding
O7A_19815	COG0804	urea catabolic process
O7A_19820	COG0832	Belongs to the urease beta subunit family
O7A_19825	COG0831	urea catabolic process
O7A_19835	COG3237	CsbD-like
O7A_19840	COG1994	Peptidase M50
O7A_19845	COG0457	Tetratricopeptide repeat
O7A_19850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
O7A_19855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
O7A_19865	COG2304	oxidoreductase activity
O7A_19875	COG2304	oxidoreductase activity
O7A_19880	COG2385	sporulation resulting in formation of a cellular spore
O7A_19885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
O7A_19895	COG4836	Membrane
O7A_19905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
O7A_19910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
O7A_19915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
O7A_19920	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
O7A_19925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
O7A_19930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
O7A_19940	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
O7A_19945	COG0356	it plays a direct role in the translocation of protons across the membrane
O7A_19955	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
O7A_19960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
O7A_19965	COG4475	Protein of unknown function (DUF436)
O7A_19970	COG0698	ribose 5-phosphate isomerase
O7A_19975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
O7A_19980	COG1971	Probably functions as a manganese efflux pump
O7A_19985	COG0009	L-threonylcarbamoyladenylate synthase
O7A_19990	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
O7A_20010	COG2890	protein-(glutamine-N5) methyltransferase activity
O7A_20015	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
O7A_20020	COG0346	lactoylglutathione lyase activity
O7A_20025	COG0789	Transcriptional regulator
O7A_20030	COG0679	Auxin Efflux Carrier
O7A_20035	COG0281	malic enzyme
O7A_20040	COG1435	thymidine kinase activity
O7A_20045	COG0254	rRNA binding
O7A_20050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
O7A_20060	COG1494	fructose-1,6-bisphosphatase
O7A_20065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
O7A_20070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
O7A_20075	COG0191	fructose-bisphosphate aldolase activity
O7A_20080	COG2204	response regulator
O7A_20085	COG4821	SIS domain
O7A_20090	COG0504	CTP synthase activity
O7A_20095	COG3343	RNA polymerase activity
O7A_20100	COG1960	acyl-CoA dehydrogenase activity
O7A_20105	COG0247	lactate metabolic process
O7A_20105	COG2181	nitrate reductase activity
O7A_20110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O7A_20115	COG4294	response to UV
O7A_20125	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
O7A_20130	COG1132	(ABC) transporter
O7A_20135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O7A_20140	COG2181	nitrate reductase activity
O7A_20145	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
O7A_20150	COG1140	nitrate reductase beta subunit
O7A_20155	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
O7A_20160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O7A_20170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O7A_20175	COG2223	nitrite transmembrane transporter activity
O7A_20180	COG0018	arginyl-trna synthetase
O7A_20185	COG4506	Protein conserved in bacteria
O7A_20195	COG0535	radical SAM domain protein
O7A_20205	COG1131	(ABC) transporter
O7A_20210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
O7A_20215	COG0612	Peptidase, M16
O7A_20220	COG0612	Peptidase, M16
O7A_20230	COG3391	amine dehydrogenase activity
O7A_20235	COG3391	amine dehydrogenase activity
O7A_20245	COG0457	Tetratricopeptide repeat
O7A_20255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
O7A_20260	COG0010	Belongs to the arginase family
O7A_20265	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
O7A_20270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O7A_20280	COG1994	Peptidase M50
O7A_20285	COG1942	4-Oxalocrotonate Tautomerase
O7A_20290	COG1846	Transcriptional regulator
O7A_20295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
O7A_20305	COG0477	Major facilitator Superfamily
O7A_20310	COG1959	2 iron, 2 sulfur cluster binding
O7A_20315	COG3465	dGTPase activity
O7A_20320	COG1078	dGTPase activity
O7A_20325	COG4844	belongs to the
O7A_20335	COG0697	spore germination
O7A_20340	COG0095	Lipoate-protein ligase
O7A_20345	COG0583	DNA-binding transcription factor activity
O7A_20350	COG0280	phosphate acetyltransferase
O7A_20360	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_20365	COG0436	Aminotransferase
O7A_20370	COG2814	Major facilitator Superfamily
O7A_20375	COG0151	Belongs to the GarS family
O7A_20380	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_20385	COG1917	Cupin 2, conserved barrel domain protein
O7A_20390	COG0077	Prephenate dehydratase
O7A_20395	COG2814	Major facilitator Superfamily
O7A_20400	COG0833	amino acid
O7A_20405	COG4187	Peptidase family M20/M25/M40
O7A_20410	COG1012	belongs to the aldehyde dehydrogenase family
O7A_20415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O7A_20425	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
O7A_20430	COG1091	dTDP-4-dehydrorhamnose reductase activity
O7A_20435	COG1088	dTDP-glucose 4,6-dehydratase activity
O7A_20440	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
O7A_20445	COG3980	spore coat polysaccharide biosynthesis protein
O7A_20450	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
O7A_20455	COG2089	acid synthase
O7A_20460	COG0456	acetyltransferase
O7A_20465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O7A_20470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O7A_20475	COG0463	Glycosyl transferase, family 2
O7A_20490	COG2363	Small membrane protein
O7A_20495	COG2233	PERMEase
O7A_20505	COG1012	belongs to the aldehyde dehydrogenase family
O7A_20510	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
O7A_20515	COG1216	Glycosyl transferase, family 2
O7A_20530	COG1695	Transcriptional regulator
O7A_20535	COG0351	phosphomethylpyrimidine kinase
O7A_20545	COG1621	beta-fructofuranosidase activity
O7A_20550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7A_20550	COG1263	PTS System
O7A_20555	COG2116	formate transmembrane transporter activity
O7A_20560	COG3711	transcriptional antiterminator
O7A_20570	COG1404	Belongs to the peptidase S8 family
O7A_20575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O7A_20580	COG0778	Nitroreductase
O7A_20585	COG0772	Belongs to the SEDS family
O7A_20595	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
O7A_20600	COG1845	cytochrome c oxidase, subunit III
O7A_20605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
O7A_20610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
O7A_20615	COG2261	transglycosylase associated protein
O7A_20620	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
O7A_20625	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
O7A_20630	COG2246	polysaccharide biosynthetic process
O7A_20635	COG1309	transcriptional regulator
O7A_20645	COG3162	membrane
O7A_20650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O7A_20655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
O7A_20660	COG2837	iron assimilation
O7A_20665	COG2822	iron ion transport
O7A_20670	COG0672	)-iron permease
O7A_20675	COG0352	thiamine-phosphate diphosphorylase activity
O7A_20680	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
O7A_20685	COG0583	DNA-binding transcription factor activity
O7A_20690	COG1380	Effector of murein hydrolase LrgA
O7A_20695	COG1346	cytolysis
O7A_20700	COG2814	Major facilitator Superfamily
O7A_20705	COG4895	conserved protein (DUF2196)
O7A_20710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
O7A_20715	COG0346	lactoylglutathione lyase activity
O7A_20725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7A_20730	COG1404	Belongs to the peptidase S8 family
O7A_20735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7A_20735	COG1263	PTS System
O7A_20740	COG3711	transcriptional antiterminator
O7A_20745	COG1442	glycosyl transferase family 8
O7A_20750	COG5522	Integral membrane protein (intg_mem_TP0381)
O7A_20755	COG1846	Transcriptional regulator
O7A_20760	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
O7A_20765	COG2234	aminopeptidase activity
O7A_20770	COG2357	RelA SpoT domain protein
O7A_20775	COG1575	Belongs to the MenA family. Type 1 subfamily
O7A_20790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O7A_20795	COG1696	Membrane protein involved in D-alanine export
O7A_20800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O7A_20805	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
O7A_20810	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
O7A_20815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O7A_20820	COG1486	melibiose metabolic process
O7A_20825	COG1447	Phosphotransferase system cellobiose-specific component IIA
O7A_20830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7A_20835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O7A_20840	COG3711	transcriptional antiterminator
O7A_20840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O7A_20850	COG2094	Belongs to the DNA glycosylase MPG family
O7A_20855	COG0753	catalase activity
O7A_20860	COG2814	Major facilitator Superfamily
O7A_20865	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
O7A_20870	COG1131	(ABC) transporter
O7A_20890	COG1595	DNA-templated transcription, initiation
O7A_20895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
O7A_20900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
O7A_20905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
O7A_20910	COG4988	ABC transporter
O7A_20915	COG1294	oxidase, subunit
O7A_20920	COG1271	oxidase subunit
O7A_20925	COG3493	citrate carrier protein
O7A_20930	COG0501	Belongs to the peptidase M48B family
O7A_20940	COG0726	polysaccharide deacetylase
O7A_20945	COG3842	ATPase activity
O7A_20950	COG2508	Transcriptional regulator
O7A_20955	COG1012	belongs to the aldehyde dehydrogenase family
O7A_20960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O7A_20970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
O7A_20975	COG1881	PFAM PEBP family protein
O7A_20980	COG0583	DNA-binding transcription factor activity
O7A_20990	COG4585	Histidine kinase
O7A_20995	COG2197	response regulator
O7A_21000	COG2195	Cleaves the N-terminal amino acid of tripeptides
O7A_21015	COG4894	glucomannan catabolic process
O7A_21020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
O7A_21025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
O7A_21030	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_21035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
O7A_21040	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
O7A_21045	COG2610	gluconate transmembrane transporter activity
O7A_21055	COG0500	methyltransferase
O7A_21060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O7A_21080	COG0753	catalase activity
O7A_21080	COG0693	protein deglycase activity
O7A_21085	COG2851	Citrate transporter
O7A_21090	COG2273	Hydrolase Family 16
O7A_21095	COG3711	transcriptional antiterminator
O7A_21105	COG2270	Major facilitator Superfamily
O7A_21110	COG0513	Belongs to the DEAD box helicase family
O7A_21115	COG2755	lipolytic protein G-D-S-L family
O7A_21115	COG3401	FG-GAP repeat protein
O7A_21170	COG3209	COG3209 Rhs family protein
O7A_21175	COG0697	spore germination
O7A_21180	COG0589	response to stress
O7A_21185	COG2723	6-phospho-beta-galactosidase activity
O7A_21190	COG1263	PTS System
O7A_21190	COG2190	(PTS) system
O7A_21190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O7A_21205	COG5444	nuclease activity
O7A_21220	COG3507	Belongs to the glycosyl hydrolase 43 family
O7A_21235	COG2986	histidine ammonia-lyase
O7A_21240	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
O7A_21245	COG1228	amidohydrolase
O7A_21250	COG0010	Belongs to the arginase family
O7A_21255	COG0833	amino acid
O7A_21260	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
O7A_21265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O7A_21270	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
O7A_21275	COG2390	Transcriptional regulator
O7A_21285	COG3192	ethanolamine utilization protein
O7A_21290	COG2079	MmgE PrpD family protein
O7A_21300	COG1126	abc transporter atp-binding protein
O7A_21305	COG0765	amino acid transport
O7A_21310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O7A_21330	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
O7A_21335	COG0561	phosphatase activity
O7A_21365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O7A_21370	COG5294	Protein conserved in bacteria
O7A_21375	COG0577	efflux transmembrane transporter activity
O7A_21380	COG1136	(ABC) transporter
O7A_21385	COG2205	protein histidine kinase activity
O7A_21390	COG0745	RESPONSE REGULATOR receiver
O7A_21395	COG0191	fructose-bisphosphate aldolase activity
O7A_21400	COG1082	Xylose isomerase domain protein TIM barrel
O7A_21405	COG1082	Xylose isomerase domain protein TIM barrel
O7A_21410	COG0673	inositol 2-dehydrogenase activity
O7A_21415	COG2814	Major facilitator Superfamily
O7A_21420	COG1082	Xylose isomerase domain protein TIM barrel
O7A_21425	COG3962	Belongs to the TPP enzyme family
O7A_21430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O7A_21435	COG3718	enzyme involved in inositol metabolism
O7A_21440	COG1012	belongs to the aldehyde dehydrogenase family
O7A_21445	COG1349	DNA-binding transcription factor activity
O7A_21450	COG0667	Aldo Keto reductase
O7A_21465	COG2814	Major facilitator Superfamily
O7A_21470	COG0326	Molecular chaperone. Has ATPase activity
O7A_21480	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_21485	COG1309	transcriptional regulator
O7A_21490	COG1012	belongs to the aldehyde dehydrogenase family
O7A_21495	COG0456	acetyltransferase
O7A_21500	COG2850	peptidyl-arginine hydroxylation
O7A_21505	COG2226	methyltransferase
O7A_21520	COG0367	asparagine synthase
O7A_21525	COG2814	Major facilitator Superfamily
O7A_21530	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
O7A_21540	COG1714	RDD family
O7A_21545	COG2311	Membrane
O7A_21550	COG1917	Cupin 2, conserved barrel domain protein
O7A_21555	COG1309	transcriptional regulator
O7A_21560	COG1028	Short-chain dehydrogenase reductase Sdr
O7A_21565	COG1846	Transcriptional regulator
O7A_21570	COG1380	Effector of murein hydrolase LrgA
O7A_21575	COG1346	cytolysis
O7A_21580	COG5039	Polysaccharide pyruvyl transferase
O7A_21585	COG1929	Belongs to the glycerate kinase type-1 family
O7A_21590	COG1802	Transcriptional regulator
O7A_21595	COG1070	Carbohydrate kinase
O7A_21600	COG2610	gluconate transmembrane transporter activity
O7A_21605	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
O7A_21610	COG0450	alkyl hydroperoxide reductase
O7A_21615	COG3634	alkyl hydroperoxide reductase activity
O7A_21620	COG2723	6-phospho-beta-galactosidase activity
O7A_21625	COG2190	(PTS) system
O7A_21630	COG2188	Transcriptional regulator
O7A_21645	COG1131	(ABC) transporter
O7A_21650	COG1994	Peptidase M50
O7A_21655	COG0535	radical SAM domain protein
O7A_21665	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
O7A_21670	COG5293	efflux transmembrane transporter activity
O7A_21680	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
O7A_21685	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
O7A_21695	COG1063	alcohol dehydrogenase
O7A_21715	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
O7A_21720	COG0456	acetyltransferase
O7A_21725	COG0457	Tetratricopeptide repeat
O7A_21735	COG0010	Belongs to the arginase family
O7A_21740	COG0833	amino acid
O7A_21745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
O7A_21750	COG3829	transcription factor binding
O7A_21755	COG5002	protein histidine kinase activity
O7A_21765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O7A_21770	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
O7A_21775	COG4853	Protein conserved in bacteria
O7A_21780	COG4863	YycH protein
O7A_21785	COG5002	protein histidine kinase activity
O7A_21790	COG0745	RESPONSE REGULATOR receiver
O7A_21820	COG0346	lactoylglutathione lyase activity
O7A_21825	COG0305	Participates in initiation and elongation during chromosome replication
O7A_21845	COG3093	addiction module antidote protein HigA
O7A_21850	COG2807	transmembrane transport
O7A_21855	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
O7A_21860	COG0359	binds to the 23S rRNA
O7A_21865	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
O7A_21870	COG4241	membrane
O7A_21880	COG5577	PFAM Coat F domain
O7A_21885	COG1733	regulation of RNA biosynthetic process
O7A_21890	COG1227	inorganic diphosphatase activity
O7A_21905	COG2271	Major facilitator Superfamily
O7A_21915	COG4319	ketosteroid isomerase
O7A_21945	COG1131	(ABC) transporter
O7A_21955	COG4319	ketosteroid isomerase
O7A_21960	COG1357	PFAM Pentapeptide repeats (8 copies)
O7A_21965	COG2814	Major facilitator Superfamily
O7A_21970	COG0583	DNA-binding transcription factor activity
O7A_21975	COG2153	protein acetylation
O7A_21985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O7A_21990	COG1846	Transcriptional regulator
O7A_21995	COG2153	protein acetylation
O7A_22000	COG2364	Membrane
O7A_22005	COG0456	acetyltransferase
O7A_22010	COG2315	Protein conserved in bacteria
O7A_22015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
O7A_22020	COG2814	Major facilitator Superfamily
O7A_22025	COG1331	Highly conserved protein containing a thioredoxin domain
O7A_22030	COG0789	Transcriptional regulator
O7A_22035	COG0697	spore germination
O7A_22040	COG1331	Highly conserved protein containing a thioredoxin domain
O7A_22045	COG1266	CAAX protease self-immunity
O7A_22050	COG0477	Major facilitator Superfamily
O7A_22050	COG2814	Major facilitator Superfamily
O7A_22055	COG0110	maltose O-acetyltransferase activity
O7A_22060	COG0346	lactoylglutathione lyase activity
O7A_22065	COG1609	Transcriptional regulator
O7A_22070	COG0708	Exodeoxyribonuclease III
O7A_22075	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
O7A_22080	COG0629	single-stranded DNA binding
O7A_22085	COG0360	Binds together with S18 to 16S ribosomal RNA
O7A_22090	COG0012	GTP binding
O7A_22095	COG0243	molybdopterin cofactor binding
O7A_22100	COG4481	Protein conserved in bacteria
O7A_22105	COG3949	Membrane
O7A_22115	COG1475	DNA binding
O7A_22120	COG1192	Involved in chromosome partitioning
O7A_22130	COG1475	DNA binding
O7A_22135	COG0357	Ribosomal RNA small subunit methyltransferase G
O7A_22140	COG0445	tRNA wobble uridine modification
O7A_22145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
O7A_22150	COG1847	R3H domain protein
O7A_22155	COG0706	membrane insertase activity
O7A_22160	COG0594	ribonuclease P activity
O7A_22165	COG0230	Belongs to the bacterial ribosomal protein bL34 family