locus-tag	class	description
BSR08_00005	COG2207	Transcriptional regulator
BSR08_00030	COG1309	transcriptional regulator
BSR08_00060	COG5578	integral membrane protein
BSR08_00065	COG2972	Histidine kinase
BSR08_00075	COG1653	transport
BSR08_00080	COG1175	transmembrane transport
BSR08_00085	COG0395	ABC-type sugar transport system, permease component
BSR08_00090	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BSR08_00095	COG2207	Transcriptional regulator
BSR08_00100	COG2755	lipolytic protein G-D-S-L family
BSR08_00110	COG5578	integral membrane protein
BSR08_00115	COG3401	FG-GAP repeat protein
BSR08_00120	COG3401	FG-GAP repeat protein
BSR08_00125	COG2755	lipolytic protein G-D-S-L family
BSR08_00140	COG1653	transport
BSR08_00145	COG4209	transmembrane transport
BSR08_00150	COG0395	ABC-type sugar transport system, permease component
BSR08_00155	COG1486	melibiose metabolic process
BSR08_00160	COG2323	membrane
BSR08_00165	COG2329	Antibiotic biosynthesis monooxygenase
BSR08_00170	COG0346	lactoylglutathione lyase activity
BSR08_00185	COG5583	Uncharacterized small protein (DUF2292)
BSR08_00190	COG0670	Belongs to the BI1 family
BSR08_00195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSR08_00205	COG3328	transposase activity
BSR08_00215	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BSR08_00215	COG2124	cytochrome p450
BSR08_00225	COG1368	sulfuric ester hydrolase activity
BSR08_00230	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSR08_00235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSR08_00240	COG1442	glycosyl transferase family 8
BSR08_00245	COG1216	Glycosyl transferase, family 2
BSR08_00250	COG1442	glycosyl transferase family 8
BSR08_00255	COG2223	nitrite transmembrane transporter activity
BSR08_00260	COG1011	Hydrolase
BSR08_00265	COG0531	amino acid
BSR08_00270	COG1012	belongs to the aldehyde dehydrogenase family
BSR08_00275	COG0840	transmembrane signaling receptor activity
BSR08_00280	COG0488	(ABC) transporter
BSR08_00290	COG0789	Transcriptional regulator
BSR08_00295	COG2814	Major facilitator Superfamily
BSR08_00310	COG2801	Transposase and inactivated derivatives
BSR08_00315	COG0488	(ABC) transporter
BSR08_00320	COG0513	Belongs to the DEAD box helicase family
BSR08_00330	COG3866	Pectate lyase
BSR08_00335	COG0471	metal ion transport
BSR08_00340	COG3290	protein histidine kinase activity
BSR08_00345	COG4565	transcriptional regulatory protein
BSR08_00350	COG3181	Tripartite tricarboxylate transporter family receptor
BSR08_00360	COG2851	Citrate transporter
BSR08_00365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSR08_00370	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BSR08_00375	COG1254	Belongs to the acylphosphatase family
BSR08_00380	COG2258	MOSC domain
BSR08_00400	COG0024	Methionine aminopeptidase
BSR08_00405	COG1263	PTS System
BSR08_00405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSR08_00410	COG1368	sulfuric ester hydrolase activity
BSR08_00420	COG1115	amino acid carrier protein
BSR08_00425	COG0531	amino acid
BSR08_00430	COG0697	spore germination
BSR08_00435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSR08_00435	COG1263	PTS System
BSR08_00440	COG0366	Alpha amylase catalytic
BSR08_00445	COG2188	Transcriptional regulator
BSR08_00450	COG0778	Nitroreductase
BSR08_00455	COG0737	Belongs to the 5'-nucleotidase family
BSR08_00460	COG0693	protein deglycase activity
BSR08_00470	COG2801	Transposase and inactivated derivatives
BSR08_00475	COG2814	Major facilitator Superfamily
BSR08_00480	COG4840	Belongs to the UPF0435 family
BSR08_00485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSR08_00490	COG4980	gas vesicle protein
BSR08_00495	COG1295	ribonuclease BN
BSR08_00505	COG0477	Major facilitator Superfamily
BSR08_00515	COG0387	Pfam Sodium calcium exchanger
BSR08_00525	COG0668	transmembrane transport
BSR08_00530	COG0535	radical SAM domain protein
BSR08_00540	COG0726	polysaccharide deacetylase
BSR08_00545	COG2084	Dehydrogenase
BSR08_00550	COG0598	Magnesium transport protein CorA
BSR08_00555	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BSR08_00560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSR08_00570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSR08_00575	COG4637	Psort location Cytoplasmic, score
BSR08_00585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSR08_00590	COG0022	dehydrogenase e1 component
BSR08_00595	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSR08_00600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSR08_00605	COG3284	Transcriptional regulator
BSR08_00615	COG1742	UPF0060 membrane protein
BSR08_00640	COG4842	Belongs to the WXG100 family
BSR08_00645	COG1486	melibiose metabolic process
BSR08_00650	COG1737	Transcriptional regulator
BSR08_00655	COG1263	PTS System
BSR08_00655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSR08_00660	COG5434	Belongs to the glycosyl hydrolase 28 family
BSR08_00665	COG1132	(ABC) transporter
BSR08_00670	COG1132	(ABC) transporter
BSR08_00675	COG2259	Doxx family
BSR08_00680	COG2514	catechol 2,3-dioxygenase activity
BSR08_00685	COG4977	sequence-specific DNA binding
BSR08_00685	COG1917	Cupin 2, conserved barrel domain protein
BSR08_00690	COG2814	Major facilitator Superfamily
BSR08_00695	COG1082	Xylose isomerase domain protein TIM barrel
BSR08_00705	COG4585	Histidine kinase
BSR08_00710	COG2197	response regulator
BSR08_00715	COG1131	(ABC) transporter
BSR08_00720	COG1511	domain protein
BSR08_00720	COG0842	Transport permease protein
BSR08_00725	COG0842	Transport permease protein
BSR08_00730	COG1695	Transcriptional regulator
BSR08_00735	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BSR08_00740	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BSR08_00745	COG1309	transcriptional regulator
BSR08_00750	COG2814	Major facilitator Superfamily
BSR08_00755	COG2318	DinB family
BSR08_00765	COG1846	Transcriptional regulator
BSR08_00770	COG0392	lysyltransferase activity
BSR08_00770	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BSR08_00775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSR08_00780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSR08_00785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSR08_00790	COG0384	phenazine biosynthesis protein PhzF
BSR08_00795	COG0778	Nitroreductase
BSR08_00810	COG1090	epimerase
BSR08_00815	COG2137	regulation of response to DNA damage stimulus
BSR08_00830	COG2814	Major facilitator Superfamily
BSR08_00845	COG3103	Sh3 type 3 domain protein
BSR08_00850	COG5658	integral membrane protein
BSR08_00855	COG0596	Alpha beta hydrolase
BSR08_00860	COG0463	Glycosyl transferase, family 2
BSR08_00865	COG4485	Bacterial membrane protein, YfhO
BSR08_00870	COG1988	membrane-bound metal-dependent
BSR08_00875	COG1194	a g-specific adenine glycosylase
BSR08_00885	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_00900	COG3557	Belongs to the UPF0374 family
BSR08_00905	COG1132	(ABC) transporter
BSR08_00910	COG4129	membrane
BSR08_00915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BSR08_00920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSR08_00925	COG0735	belongs to the Fur family
BSR08_01040	COG4326	sporulation control protein
BSR08_01050	COG5577	PFAM Coat F domain
BSR08_01055	COG3340	Belongs to the peptidase S51 family
BSR08_01060	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BSR08_01075	COG0753	catalase activity
BSR08_01080	COG1116	anion transmembrane transporter activity
BSR08_01085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSR08_01090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSR08_01095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSR08_01105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSR08_01115	COG1476	TRANSCRIPTIONal
BSR08_01125	COG3382	B3 4 domain protein
BSR08_01130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BSR08_01140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSR08_01145	COG0789	Transcriptional regulator
BSR08_01150	COG1664	Polymer-forming cytoskeletal
BSR08_01155	COG1664	Polymer-forming cytoskeletal
BSR08_01160	COG2766	serine protein kinase
BSR08_01165	COG2718	Belongs to the UPF0229 family
BSR08_01175	COG1846	Transcriptional regulator
BSR08_01180	COG1566	PFAM secretion protein HlyD family protein
BSR08_01185	COG2814	Major facilitator Superfamily
BSR08_01190	COG0655	NAD(P)H dehydrogenase (quinone) activity
BSR08_01205	COG1725	Transcriptional regulator
BSR08_01210	COG1131	(ABC) transporter
BSR08_01215	COG1131	(ABC) transporter
BSR08_01220	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BSR08_01225	COG1278	Cold shock
BSR08_01235	COG1464	Belongs to the NlpA lipoprotein family
BSR08_01240	COG3706	GGDEF domain
BSR08_01245	COG1823	symporter activity
BSR08_01250	COG5444	nuclease activity
BSR08_01275	COG0582	viral genome integration into host DNA
BSR08_01325	COG5644	endopeptidase inhibitor activity
BSR08_01330	COG0741	lytic transglycosylase activity
BSR08_01330	COG0791	NLP P60 protein
BSR08_01350	COG0457	Tetratricopeptide repeat
BSR08_01375	COG4085	toxin activity
BSR08_01375	COG1525	nuclease
BSR08_01375	COG0737	Belongs to the 5'-nucleotidase family
BSR08_01380	COG3764	Sortase (surface protein transpeptidase)
BSR08_01385	COG0564	pseudouridine synthase activity
BSR08_01395	COG0517	IMP dehydrogenase activity
BSR08_01400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSR08_01405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSR08_01405	COG3153	acetyltransferase
BSR08_01410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSR08_01415	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BSR08_01420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BSR08_01425	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSR08_01430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BSR08_01435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSR08_01440	COG4585	Histidine kinase
BSR08_01440	COG2203	Gaf domain
BSR08_01445	COG2197	response regulator
BSR08_01450	COG0431	NADPH-dependent FMN reductase
BSR08_01465	COG0791	NLP P60 protein
BSR08_01465	COG1388	LysM domain
BSR08_01470	COG1959	2 iron, 2 sulfur cluster binding
BSR08_01475	COG0668	transmembrane transport
BSR08_01480	COG2719	SpoVR family
BSR08_01485	COG1785	Belongs to the alkaline phosphatase family
BSR08_01490	COG1388	LysM domain
BSR08_01490	COG0791	NLP P60 protein
BSR08_01495	COG0583	DNA-binding transcription factor activity
BSR08_01500	COG0372	Belongs to the citrate synthase family
BSR08_01505	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_01510	COG0531	amino acid
BSR08_01515	COG0733	neurotransmitter:sodium symporter activity
BSR08_01520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSR08_01525	COG0456	acetyltransferase
BSR08_01540	COG1595	DNA-templated transcription, initiation
BSR08_01545	COG0667	Aldo Keto reductase
BSR08_01550	COG0204	Acyl-transferase
BSR08_01555	COG1253	flavin adenine dinucleotide binding
BSR08_01560	COG0789	Transcriptional regulator
BSR08_01570	COG1253	flavin adenine dinucleotide binding
BSR08_01575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSR08_01580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSR08_01585	COG0584	glycerophosphoryl diester phosphodiesterase
BSR08_01595	COG0668	transmembrane transport
BSR08_01600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BSR08_01605	COG0726	polysaccharide deacetylase
BSR08_01610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSR08_01615	COG1757	Na H antiporter
BSR08_01620	COG0589	response to stress
BSR08_01630	COG1132	(ABC) transporter
BSR08_01635	COG1132	(ABC) transporter
BSR08_01640	COG0702	epimerase
BSR08_01660	COG0189	ligase activity
BSR08_01665	COG0189	ligase activity
BSR08_01670	COG4399	Belongs to the UPF0754 family
BSR08_01675	COG3679	Belongs to the UPF0342 family
BSR08_01685	COG0561	phosphatase activity
BSR08_01690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSR08_01695	COG0475	glutathione-regulated potassium exporter activity
BSR08_01700	COG0490	domain, Protein
BSR08_01710	COG1024	Enoyl-CoA hydratase
BSR08_01720	COG4152	abc transporter atp-binding protein
BSR08_01725	COG1668	transmembrane transport
BSR08_01730	COG0420	3'-5' exonuclease activity
BSR08_01735	COG4717	serine-type aminopeptidase activity
BSR08_01740	COG3481	metal-dependent phosphohydrolase, HD sub domain
BSR08_01750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSR08_01780	COG1846	Transcriptional regulator
BSR08_01785	COG4980	gas vesicle protein
BSR08_01800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BSR08_01805	COG0537	adenosine 5'-monophosphoramidase activity
BSR08_01810	COG1131	(ABC) transporter
BSR08_01815	COG4473	ABC transporter
BSR08_01825	COG1473	amidohydrolase
BSR08_01830	COG3069	C4-dicarboxylate transmembrane transporter activity
BSR08_01840	COG2329	Antibiotic biosynthesis monooxygenase
BSR08_01845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSR08_01850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSR08_01865	COG1309	transcriptional regulator
BSR08_01870	COG1511	domain protein
BSR08_01875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSR08_01880	COG4377	Putative membrane peptidase family (DUF2324)
BSR08_01890	COG1363	Peptidase, m42
BSR08_01895	COG4405	Protein conserved in bacteria
BSR08_01900	COG1301	dicarboxylic acid transport
BSR08_01910	COG1234	tRNA 3'-trailer cleavage
BSR08_01915	COG0095	Lipoate-protein ligase
BSR08_01920	COG0702	epimerase
BSR08_01925	COG0318	PFAM AMP-dependent synthetase and ligase
BSR08_01935	COG0501	Belongs to the peptidase M48B family
BSR08_01945	COG0456	acetyltransferase
BSR08_01950	COG0604	alcohol dehydrogenase
BSR08_01955	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BSR08_01960	COG0406	alpha-ribazole phosphatase activity
BSR08_01965	COG0183	Belongs to the thiolase family
BSR08_01970	COG0318	PFAM AMP-dependent synthetase and ligase
BSR08_01975	COG1268	BioY protein
BSR08_01980	COG0840	transmembrane signaling receptor activity
BSR08_01990	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_02000	COG4903	ComK protein
BSR08_02005	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_02015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSR08_02030	COG0398	Pfam SNARE associated Golgi protein
BSR08_02035	COG0681	Belongs to the peptidase S26 family
BSR08_02040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSR08_02045	COG1846	Transcriptional regulator
BSR08_02060	COG0738	Major facilitator superfamily
BSR08_02065	COG0673	inositol 2-dehydrogenase activity
BSR08_02070	COG0561	phosphatase activity
BSR08_02075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSR08_02080	COG1609	Transcriptional regulator
BSR08_02085	COG3180	Ammonia monooxygenase
BSR08_02090	COG2814	Major facilitator Superfamily
BSR08_02090	COG0477	Major facilitator Superfamily
BSR08_02095	COG4533	DNA binding
BSR08_02115	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BSR08_02120	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BSR08_02125	COG1074	ATP-dependent DNA helicase activity
BSR08_02130	COG0420	3'-5' exonuclease activity
BSR08_02135	COG0419	ATPase involved in DNA repair
BSR08_02140	COG1403	HNH endonuclease
BSR08_02185	COG5337	Spore coat protein CotH
BSR08_02190	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSR08_02200	COG1404	Belongs to the peptidase S8 family
BSR08_02210	COG0367	asparagine synthase
BSR08_02215	COG1562	ergosterol biosynthetic process
BSR08_02220	COG0534	Mate efflux family protein
BSR08_02225	COG1917	Cupin 2, conserved barrel domain protein
BSR08_02225	COG2207	Transcriptional regulator
BSR08_02230	COG1609	Transcriptional regulator
BSR08_02235	COG0673	inositol 2-dehydrogenase activity
BSR08_02240	COG2318	DinB family
BSR08_02245	COG1279	arginine transmembrane transporter activity
BSR08_02250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSR08_02255	COG1357	PFAM Pentapeptide repeats (8 copies)
BSR08_02260	COG2267	carboxylic ester hydrolase activity
BSR08_02270	COG2153	protein acetylation
BSR08_02275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BSR08_02275	COG0646	methionine synthase
BSR08_02280	COG1666	GTP binding
BSR08_02285	COG2996	Protein conserved in bacteria
BSR08_02295	COG1307	EDD domain protein, DegV family
BSR08_02300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSR08_02320	COG0561	phosphatase activity
BSR08_02325	COG1073	alpha beta
BSR08_02330	COG2151	metal-sulfur cluster biosynthetic enzyme
BSR08_02350	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BSR08_02365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSR08_02370	COG0505	Belongs to the CarA family
BSR08_02375	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BSR08_02380	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BSR08_02385	COG2801	Transposase and inactivated derivatives
BSR08_02415	COG1744	ABC transporter substrate-binding protein PnrA-like
BSR08_02430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSR08_02435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSR08_02440	COG5504	Zn-dependent protease
BSR08_02445	COG0444	Belongs to the ABC transporter superfamily
BSR08_02450	COG4608	Belongs to the ABC transporter superfamily
BSR08_02460	COG0601	transmembrane transport
BSR08_02465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSR08_02475	COG0180	Tryptophanyl-tRNA synthetase
BSR08_02480	COG4166	transmembrane transport
BSR08_02485	COG0601	transmembrane transport
BSR08_02490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSR08_02495	COG0444	Belongs to the ABC transporter superfamily
BSR08_02500	COG4608	Belongs to the ABC transporter superfamily
BSR08_02505	COG2814	Major facilitator Superfamily
BSR08_02510	COG0456	acetyltransferase
BSR08_02515	COG1393	Belongs to the ArsC family
BSR08_02520	COG0861	Integral membrane protein TerC family
BSR08_02525	COG4862	establishment of competence for transformation
BSR08_02530	COG4469	Competence protein
BSR08_02535	COG1164	Oligoendopeptidase f
BSR08_02555	COG2346	COG2346, Truncated hemoglobins
BSR08_02560	COG0741	lytic transglycosylase activity
BSR08_02565	COG4116	CYTH
BSR08_02575	COG2357	RelA SpoT domain protein
BSR08_02580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSR08_02585	COG0564	pseudouridine synthase activity
BSR08_02590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BSR08_02595	COG0569	domain protein
BSR08_02595	COG0475	glutathione-regulated potassium exporter activity
BSR08_02600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BSR08_02605	COG0352	thiamine-phosphate diphosphorylase activity
BSR08_02610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSR08_02615	COG2104	thiamine diphosphate biosynthetic process
BSR08_02620	COG2022	thiamine diphosphate biosynthetic process
BSR08_02625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSR08_02630	COG0351	phosphomethylpyrimidine kinase
BSR08_02635	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSR08_02695	COG0210	DNA helicase
BSR08_02705	COG2153	protein acetylation
BSR08_02710	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BSR08_02715	COG2382	esterase
BSR08_02720	COG0626	cystathionine gamma-synthase activity
BSR08_02725	COG0626	cystathionine gamma-synthase activity
BSR08_02730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSR08_02735	COG5505	Protein of unknown function (DUF819)
BSR08_02770	COG1396	sequence-specific DNA binding
BSR08_02850	COG0457	Tetratricopeptide repeat
BSR08_02855	COG5444	nuclease activity
BSR08_02865	COG3328	transposase activity
BSR08_02925	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BSR08_02935	COG3711	transcriptional antiterminator
BSR08_02935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSR08_02940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSR08_02940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BSR08_02940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BSR08_02945	COG1482	cell wall glycoprotein biosynthetic process
BSR08_02960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSR08_02970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BSR08_02990	COG0109	protoheme IX farnesyltransferase activity
BSR08_03000	COG0726	polysaccharide deacetylase
BSR08_03020	COG5504	Zn-dependent protease
BSR08_03025	COG2205	protein histidine kinase activity
BSR08_03040	COG2427	Protein of unknown function (DUF1641)
BSR08_03050	COG1051	belongs to the nudix hydrolase family
BSR08_03060	COG2124	cytochrome p450
BSR08_03065	COG1819	glycosyl
BSR08_03075	COG1587	Uroporphyrinogen-III synthase
BSR08_03080	COG0390	transport system, permease component
BSR08_03085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSR08_03090	COG0697	spore germination
BSR08_03105	COG1252	NADH dehydrogenase
BSR08_03110	COG1904	glucuronate isomerase
BSR08_03115	COG2211	Major facilitator Superfamily
BSR08_03120	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BSR08_03125	COG1063	alcohol dehydrogenase
BSR08_03130	COG1312	Catalyzes the dehydration of D-mannonate
BSR08_03135	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_03140	COG2271	Major facilitator Superfamily
BSR08_03145	COG1609	Transcriptional regulator
BSR08_03150	COG0246	Mannitol dehydrogenase
BSR08_03155	COG2721	sulfolactate sulfo-lyase activity
BSR08_03160	COG0730	response to heat
BSR08_03165	COG2318	DinB family
BSR08_03175	COG2801	Transposase and inactivated derivatives
BSR08_03185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSR08_03190	COG0457	Tetratricopeptide repeat
BSR08_03205	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_03205	COG1388	LysM domain
BSR08_03205	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSR08_03215	COG4195	phage-related replication protein
BSR08_03220	COG3546	catalase activity
BSR08_03225	COG2856	Zn peptidase
BSR08_03230	COG1396	sequence-specific DNA binding
BSR08_03240	COG1522	sequence-specific DNA binding
BSR08_03245	COG1484	DNA-dependent DNA replication
BSR08_03270	COG1595	DNA-templated transcription, initiation
BSR08_03275	COG5484	DNA packaging
BSR08_03275	COG3728	DNA packaging
BSR08_03280	COG1783	phage Terminase large subunit
BSR08_03285	COG5518	Phage portal protein
BSR08_03290	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BSR08_03295	COG4653	Phage capsid family
BSR08_03345	COG3953	SLT domain
BSR08_03345	COG5412	phage tail tape measure protein
BSR08_03345	COG5412	phage tail tape measure protein
BSR08_03345	COG3953	SLT domain
BSR08_03345	COG5412	phage tail tape measure protein
BSR08_03345	COG3953	SLT domain
BSR08_03350	COG1652	LysM domain
BSR08_03355	COG4193	domain, Protein
BSR08_03365	COG3628	GPW Gp25 family protein
BSR08_03370	COG3299	homolog of phage Mu protein gp47
BSR08_03375	COG3778	Protein conserved in bacteria
BSR08_03415	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_03415	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSR08_03430	COG0306	phosphate transporter
BSR08_03435	COG1392	Phosphate transport regulator
BSR08_03440	COG0531	amino acid
BSR08_03445	COG0346	lactoylglutathione lyase activity
BSR08_03450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BSR08_03455	COG0463	Glycosyl transferase, family 2
BSR08_03465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSR08_03470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSR08_03475	COG2362	D-Aminopeptidase
BSR08_03480	COG0601	transmembrane transport
BSR08_03485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSR08_03490	COG0444	Belongs to the ABC transporter superfamily
BSR08_03495	COG4166	transmembrane transport
BSR08_03500	COG1619	proteins homologs of microcin C7 resistance protein MccF
BSR08_03505	COG4948	Mandelate Racemase Muconate Lactonizing
BSR08_03510	COG0791	NLP P60 protein
BSR08_03515	COG4608	Belongs to the ABC transporter superfamily
BSR08_03520	COG2706	6-phosphogluconolactonase activity
BSR08_03530	COG1607	acyl-coa hydrolase
BSR08_03535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSR08_03535	COG1017	nitric oxide dioxygenase activity
BSR08_03545	COG2323	membrane
BSR08_03550	COG2318	DinB family
BSR08_03555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSR08_03560	COG2076	Multidrug Resistance protein
BSR08_03565	COG2076	Multidrug Resistance protein
BSR08_03570	COG0788	formyltetrahydrofolate deformylase activity
BSR08_03575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSR08_03580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSR08_03585	COG1764	response to oxidative stress
BSR08_03590	COG1846	Transcriptional regulator
BSR08_03595	COG1764	response to oxidative stress
BSR08_03605	COG0590	tRNA wobble adenosine to inosine editing
BSR08_03610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BSR08_03615	COG1404	Belongs to the peptidase S8 family
BSR08_03620	COG1366	Belongs to the anti-sigma-factor antagonist family
BSR08_03625	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BSR08_03630	COG1122	ATPase activity
BSR08_03635	COG4721	ABC-type cobalt transport system, permease component
BSR08_03645	COG0745	RESPONSE REGULATOR receiver
BSR08_03650	COG3850	Histidine kinase
BSR08_03650	COG5002	protein histidine kinase activity
BSR08_03655	COG3212	peptidase
BSR08_03660	COG3212	peptidase
BSR08_03680	COG2239	Acts as a magnesium transporter
BSR08_03685	COG0789	Transcriptional regulator
BSR08_03700	COG1846	Transcriptional regulator
BSR08_03705	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSR08_03710	COG0726	polysaccharide deacetylase
BSR08_03715	COG1408	metallophosphoesterase
BSR08_03725	COG0463	Glycosyl transferase, family 2
BSR08_03730	COG3285	dna ligase
BSR08_03730	COG1793	dna ligase
BSR08_03735	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BSR08_03740	COG5001	Diguanylate cyclase
BSR08_03740	COG3300	MHYT domain
BSR08_03745	COG0586	Pfam SNARE associated Golgi protein
BSR08_03750	COG0861	Integral membrane protein TerC family
BSR08_03755	COG1191	sigma factor activity
BSR08_03775	COG0501	Belongs to the peptidase M48B family
BSR08_03780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSR08_03800	COG3594	Acyltransferase
BSR08_03805	COG5002	protein histidine kinase activity
BSR08_03810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSR08_03820	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BSR08_03825	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BSR08_03830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSR08_03835	COG0436	Aminotransferase
BSR08_03840	COG1850	ribulose-bisphosphate carboxylase activity
BSR08_03845	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BSR08_03850	COG0235	Class ii aldolase
BSR08_03855	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BSR08_03860	COG3339	Conserved Protein
BSR08_03875	COG3852	Histidine kinase
BSR08_03880	COG1846	Transcriptional regulator
BSR08_03885	COG1360	Flagellar Motor Protein
BSR08_03890	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BSR08_03895	COG0542	response to heat
BSR08_03900	COG3949	Membrane
BSR08_03905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BSR08_03910	COG0720	synthase
BSR08_03915	COG0602	queuosine metabolic process
BSR08_03920	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BSR08_03930	COG4873	Protein conserved in bacteria
BSR08_03945	COG3773	Cell wall hydrolase
BSR08_03950	COG2244	polysaccharide biosynthetic process
BSR08_03955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSR08_03960	COG2217	Heavy metal translocating P-type atpase
BSR08_03970	COG0006	proline dipeptidase activity
BSR08_03980	COG1609	Transcriptional regulator
BSR08_03985	COG3711	transcriptional antiterminator
BSR08_03990	COG1263	PTS System
BSR08_03990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSR08_03990	COG2190	(PTS) system
BSR08_03995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSR08_04000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSR08_04010	COG1533	DNA photolyase activity
BSR08_04015	COG0456	acetyltransferase
BSR08_04020	COG0840	transmembrane signaling receptor activity
BSR08_04025	COG2084	Dehydrogenase
BSR08_04030	COG3328	transposase activity
BSR08_04035	COG2340	Cysteine-rich secretory protein family
BSR08_04040	COG0768	penicillin binding
BSR08_04060	COG0436	Aminotransferase
BSR08_04070	COG0835	chemotaxis
BSR08_04070	COG0784	Response regulator, receiver
BSR08_04080	COG2814	Major facilitator Superfamily
BSR08_04085	COG1376	ErfK ybiS ycfS ynhG family protein
BSR08_04090	COG1408	metallophosphoesterase
BSR08_04095	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_04100	COG2200	EAL domain
BSR08_04110	COG4703	Protein of unknown function (DUF1797)
BSR08_04115	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BSR08_04125	COG0517	IMP dehydrogenase activity
BSR08_04130	COG0583	DNA-binding transcription factor activity
BSR08_04135	COG0716	FMN binding
BSR08_04145	COG0716	FMN binding
BSR08_04150	COG2171	N-acyltransferase activity
BSR08_04155	COG1473	amidohydrolase
BSR08_04165	COG0668	transmembrane transport
BSR08_04170	COG0450	alkyl hydroperoxide reductase
BSR08_04175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSR08_04185	COG2801	Transposase and inactivated derivatives
BSR08_04200	COG0746	molybdenum cofactor guanylyltransferase activity
BSR08_04205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSR08_04210	COG0303	'Molybdopterin
BSR08_04215	COG1763	Mo-molybdopterin cofactor biosynthetic process
BSR08_04220	COG0314	molybdopterin synthase activity
BSR08_04225	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BSR08_04235	COG1132	(ABC) transporter
BSR08_04245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSR08_04250	COG1136	(ABC) transporter
BSR08_04255	COG0577	efflux transmembrane transporter activity
BSR08_04260	COG1349	DNA-binding transcription factor activity
BSR08_04265	COG1105	Belongs to the carbohydrate kinase PfkB family
BSR08_04270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BSR08_04270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BSR08_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSR08_04275	COG0681	Belongs to the peptidase S26 family
BSR08_04285	COG0488	(ABC) transporter
BSR08_04290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BSR08_04295	COG2309	aminopeptidase activity
BSR08_04305	COG1077	Cell shape determining protein MreB Mrl
BSR08_04310	COG2002	toxin-antitoxin pair type II binding
BSR08_04315	COG3852	Histidine kinase
BSR08_04320	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BSR08_04320	COG2105	PFAM AIG2 family protein
BSR08_04325	COG0569	domain protein
BSR08_04330	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BSR08_04335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BSR08_04345	COG0561	phosphatase activity
BSR08_04350	COG0242	peptide deformylase activity
BSR08_04365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSR08_04370	COG0022	dehydrogenase e1 component
BSR08_04375	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSR08_04380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSR08_04385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSR08_04395	COG1982	Orn Lys Arg decarboxylase major
BSR08_04400	COG4476	Belongs to the UPF0223 family
BSR08_04405	COG4493	Belongs to the UPF0637 family
BSR08_04415	COG0483	inositol monophosphate 1-phosphatase activity
BSR08_04430	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BSR08_04485	COG4896	Protein conserved in bacteria
BSR08_04495	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BSR08_04500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSR08_04505	COG2066	Belongs to the glutaminase family
BSR08_04510	COG4838	Belongs to the UPF0358 family
BSR08_04515	COG0772	Belongs to the SEDS family
BSR08_04520	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BSR08_04525	COG1612	heme a metabolic process
BSR08_04530	COG0109	protoheme IX farnesyltransferase activity
BSR08_04535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSR08_04535	COG2010	Cytochrome c
BSR08_04540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSR08_04545	COG1845	cytochrome c oxidase, subunit III
BSR08_04550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSR08_04555	COG3336	cytochrome c oxidase
BSR08_04565	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BSR08_04570	COG2340	Cysteine-rich secretory protein family
BSR08_04585	COG3679	Belongs to the UPF0342 family
BSR08_04590	COG4471	UPF0298 protein
BSR08_04595	COG0742	ribosomal rna small subunit methyltransferase
BSR08_04600	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BSR08_04605	COG3314	Sporulation integral membrane protein YlbJ
BSR08_04610	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSR08_04615	COG3480	Lon protease (S16) C-terminal proteolytic domain
BSR08_04620	COG1323	Belongs to the UPF0348 family
BSR08_04630	COG1399	metal-binding, possibly nucleic acid-binding protein
BSR08_04635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BSR08_04645	COG0454	-acetyltransferase
BSR08_04650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BSR08_04655	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BSR08_04660	COG2001	Belongs to the MraZ family
BSR08_04665	COG0275	rRNA processing
BSR08_04670	COG4839	cell division protein FtsL
BSR08_04685	COG0768	penicillin binding
BSR08_04695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSR08_04705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSR08_04710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSR08_04715	COG0772	Belongs to the SEDS family
BSR08_04720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSR08_04725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSR08_04730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BSR08_04735	COG3879	Bacterial protein of unknown function (DUF881)
BSR08_04740	COG3879	Bacterial protein of unknown function (DUF881)
BSR08_04745	COG3856	small basic protein
BSR08_04750	COG0849	cell division
BSR08_04755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BSR08_04760	COG4412	M6 family metalloprotease domain protein
BSR08_04760	COG1404	Belongs to the peptidase S8 family
BSR08_04770	COG1191	sigma factor activity
BSR08_04775	COG1191	sigma factor activity
BSR08_04780	COG1119	ATPase activity
BSR08_04785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSR08_04790	COG1873	PFAM PRC-barrel domain
BSR08_04800	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BSR08_04805	COG1799	cell septum assembly
BSR08_04810	COG0762	integral membrane protein
BSR08_04815	COG2302	S4 RNA-binding domain
BSR08_04820	COG3599	regulation of cell shape
BSR08_04825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSR08_04830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BSR08_04835	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSR08_04840	COG0564	pseudouridine synthase activity
BSR08_04845	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BSR08_04850	COG2233	PERMEase
BSR08_04855	COG0540	Belongs to the ATCase OTCase family
BSR08_04860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSR08_04865	COG0505	Belongs to the CarA family
BSR08_04870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BSR08_04875	COG0543	2 iron, 2 sulfur cluster binding
BSR08_04880	COG0167	dihydroorotate dehydrogenase activity
BSR08_04885	COG0284	orotidine-5'-phosphate decarboxylase activity
BSR08_04890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BSR08_04895	COG0175	sulfate reduction
BSR08_04900	COG0306	phosphate transporter
BSR08_04905	COG2046	Belongs to the sulfate adenylyltransferase family
BSR08_04910	COG0529	Catalyzes the synthesis of activated sulfate
BSR08_04915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSR08_04920	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BSR08_04925	COG1648	precorrin-2 dehydrogenase activity
BSR08_04935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BSR08_04940	COG1561	YicC-like family, N-terminal region
BSR08_04945	COG2052	Domain of unknown function (DUF370)
BSR08_04950	COG0194	GDP metabolic process
BSR08_04955	COG1758	RNA polymerase activity
BSR08_04960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSR08_04965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BSR08_04970	COG0242	peptide deformylase activity
BSR08_04975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSR08_04980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSR08_04980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSR08_04985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSR08_04990	COG0631	protein serine/threonine phosphatase activity
BSR08_04995	COG0515	serine threonine protein kinase
BSR08_04995	COG2815	serine threonine protein kinase
BSR08_05000	COG1162	GTPase activity
BSR08_05005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BSR08_05010	COG1564	THIamine pyrophosphokinase
BSR08_05020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSR08_05025	COG1302	Protein conserved in bacteria
BSR08_05030	COG1461	Dihydroxyacetone kinase
BSR08_05035	COG1760	l-serine dehydratase
BSR08_05040	COG1760	l-serine dehydratase
BSR08_05045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BSR08_05050	COG1349	DNA-binding transcription factor activity
BSR08_05050	COG2050	protein possibly involved in aromatic compounds catabolism
BSR08_05055	COG0416	fatty acid biosynthetic process
BSR08_05060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSR08_05065	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_05070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSR08_05075	COG0571	ribonuclease III activity
BSR08_05080	COG1196	nuclear chromosome segregation
BSR08_05085	COG0552	protein localization to endoplasmic reticulum
BSR08_05095	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BSR08_05100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSR08_05105	COG0228	four-way junction DNA binding
BSR08_05110	COG1837	Belongs to the UPF0109 family
BSR08_05120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSR08_05125	COG0336	Belongs to the RNA methyltransferase TrmD family
BSR08_05130	COG0335	large ribosomal subunit rRNA binding
BSR08_05135	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BSR08_05140	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSR08_05150	COG2257	FlhB HrpN YscU SpaS Family
BSR08_05155	COG0045	succinate-CoA ligase (ADP-forming) activity
BSR08_05160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BSR08_05165	COG0758	DNA mediated transformation
BSR08_05170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSR08_05175	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BSR08_05180	COG4974	Belongs to the 'phage' integrase family
BSR08_05185	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BSR08_05190	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BSR08_05195	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BSR08_05200	COG1815	bacterial-type flagellum-dependent cell motility
BSR08_05205	COG1558	bacterial-type flagellum-dependent cell motility
BSR08_05210	COG1677	Flagellar hook-basal body complex protein FliE
BSR08_05220	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSR08_05225	COG1317	bacterial-type flagellum organization
BSR08_05230	COG1157	protein secretion by the type III secretion system
BSR08_05235	COG2882	bacterial-type flagellum organization
BSR08_05240	COG3334	PFAM MgtE intracellular
BSR08_05245	COG3144	bacterial-type flagellum assembly
BSR08_05250	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BSR08_05255	COG4786	Flagellar basal body rod
BSR08_05260	COG1582	Flagellar protein (FlbD)
BSR08_05265	COG1580	Controls the rotational direction of flagella during chemotaxis
BSR08_05270	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSR08_05275	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSR08_05275	COG1776	CheC inhibitor of MCP methylation
BSR08_05280	COG2201	protein-glutamate methylesterase activity
BSR08_05285	COG3190	flagellar
BSR08_05290	COG1338	Plays a role in the flagellum-specific transport system
BSR08_05295	COG1987	bacterial-type flagellum assembly
BSR08_05300	COG1684	flagellar biosynthetic protein fliR
BSR08_05305	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSR08_05310	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSR08_05315	COG1419	protein localization to endoplasmic reticulum
BSR08_05320	COG0455	bacterial-type flagellum organization
BSR08_05325	COG2201	protein-glutamate methylesterase activity
BSR08_05330	COG2198	Histidine kinase
BSR08_05330	COG0643	Histidine kinase
BSR08_05335	COG0835	chemotaxis
BSR08_05345	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BSR08_05350	COG1191	sigma factor activity
BSR08_05360	COG0052	Belongs to the universal ribosomal protein uS2 family
BSR08_05365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BSR08_05370	COG0528	UMP kinase activity
BSR08_05375	COG0233	cytoplasmic translational termination
BSR08_05380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSR08_05385	COG4589	Belongs to the CDS family
BSR08_05390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BSR08_05395	COG0750	zinc metalloprotease
BSR08_05400	COG0442	prolyl-tRNA aminoacylation
BSR08_05405	COG2176	DNA-directed DNA polymerase activity
BSR08_05410	COG0779	Required for maturation of 30S ribosomal subunits
BSR08_05415	COG0195	Participates in both transcription termination and antitermination
BSR08_05420	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BSR08_05425	COG1358	cellular component organization or biogenesis
BSR08_05430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSR08_05435	COG1550	Protein conserved in bacteria
BSR08_05440	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSR08_05445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSR08_05450	COG0196	riboflavin kinase activity
BSR08_05455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BSR08_05460	COG1185	polyribonucleotide nucleotidyltransferase activity
BSR08_05465	COG0726	polysaccharide deacetylase
BSR08_05470	COG0612	Peptidase, M16
BSR08_05475	COG1873	PFAM PRC-barrel domain
BSR08_05480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSR08_05485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSR08_05490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BSR08_05495	COG0527	aspartate kinase activity
BSR08_05500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSR08_05505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BSR08_05510	COG0740	serine-type endopeptidase activity
BSR08_05520	COG4980	gas vesicle protein
BSR08_05520	COG1674	ftsk spoiiie
BSR08_05525	COG2188	Transcriptional regulator
BSR08_05530	COG2814	Major facilitator Superfamily
BSR08_05535	COG0612	Peptidase, M16
BSR08_05540	COG0612	Peptidase, M16
BSR08_05545	COG0300	oxidoreductase activity
BSR08_05560	COG1426	Protein conserved in bacteria
BSR08_05565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSR08_05570	COG1546	Belongs to the CinA family
BSR08_05570	COG1058	Belongs to the CinA family
BSR08_05575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BSR08_05580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSR08_05585	COG1418	mRNA catabolic process
BSR08_05590	COG1692	metallophosphoesterase
BSR08_05595	COG2359	stage V sporulation protein S
BSR08_05600	COG1063	alcohol dehydrogenase
BSR08_05605	COG0156	8-amino-7-oxononanoate synthase activity
BSR08_05610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSR08_05615	COG4550	Control of competence regulator ComK, YlbF/YmcA
BSR08_05625	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BSR08_05630	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BSR08_05735	COG3226	Transcriptional regulator
BSR08_05745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSR08_05750	COG1404	Belongs to the peptidase S8 family
BSR08_05760	COG4195	phage-related replication protein
BSR08_05765	COG1764	response to oxidative stress
BSR08_05770	COG2076	Multidrug Resistance protein
BSR08_05775	COG2076	Multidrug Resistance protein
BSR08_05790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSR08_05795	COG1923	regulation of RNA biosynthetic process
BSR08_05810	COG1780	Probably involved in ribonucleotide reductase function
BSR08_05815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSR08_05820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSR08_05825	COG4112	unkown
BSR08_05830	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSR08_05840	COG0464	growth
BSR08_05850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSR08_05855	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BSR08_05860	COG0789	Transcriptional regulator
BSR08_05865	COG0174	glutamine synthetase
BSR08_05870	COG4974	Belongs to the 'phage' integrase family
BSR08_05890	COG3645	SOS response
BSR08_05890	COG3646	Phage regulatory protein
BSR08_06035	COG3953	SLT domain
BSR08_06035	COG5412	phage tail tape measure protein
BSR08_06080	COG1388	LysM domain
BSR08_06080	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSR08_06080	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_06090	COG5444	nuclease activity
BSR08_06130	COG4282	regulation of fungal-type cell wall biogenesis
BSR08_06165	COG3655	Transcriptional regulator
BSR08_06190	COG0135	phosphoribosylanthranilate isomerase activity
BSR08_06195	COG2211	Major facilitator Superfamily
BSR08_06210	COG3507	Belongs to the glycosyl hydrolase 43 family
BSR08_06215	COG1940	carbohydrate kinase activity
BSR08_06220	COG2115	Belongs to the xylose isomerase family
BSR08_06225	COG1070	Carbohydrate kinase
BSR08_06235	COG3328	transposase activity
BSR08_06240	COG1525	nuclease
BSR08_06245	COG2814	Major facilitator Superfamily
BSR08_06250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSR08_06265	COG0756	dUTP diphosphatase activity
BSR08_06305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSR08_06325	COG3832	glyoxalase III activity
BSR08_06375	COG4195	phage-related replication protein
BSR08_06385	COG0346	lactoylglutathione lyase activity
BSR08_06400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSR08_06405	COG1388	LysM domain
BSR08_06410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSR08_06415	COG4224	UPF0291 protein
BSR08_06420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BSR08_06430	COG3763	UPF0154 protein
BSR08_06440	COG0785	Cytochrome C biogenesis protein
BSR08_06445	COG2201	protein-glutamate methylesterase activity
BSR08_06450	COG4846	Membrane protein involved in cytochrome C biogenesis
BSR08_06460	COG0071	Belongs to the small heat shock protein (HSP20) family
BSR08_06475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BSR08_06480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSR08_06500	COG0824	Thioesterase
BSR08_06510	COG4841	protein insertion into membrane
BSR08_06515	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BSR08_06520	COG1832	CoA-binding protein
BSR08_06525	COG0187	DNA topoisomerase II activity
BSR08_06530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSR08_06545	COG1115	amino acid carrier protein
BSR08_06550	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BSR08_06560	COG5520	Belongs to the glycosyl hydrolase 30 family
BSR08_06570	COG2246	polysaccharide biosynthetic process
BSR08_06575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSR08_06580	COG0586	Pfam SNARE associated Golgi protein
BSR08_06585	COG2404	hydrolase activity, acting on ester bonds
BSR08_06590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSR08_06595	COG1024	Enoyl-CoA hydratase
BSR08_06600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSR08_06605	COG0511	ligase activity, forming carbon-carbon bonds
BSR08_06610	COG0439	Biotin carboxylase
BSR08_06615	COG0318	PFAM AMP-dependent synthetase and ligase
BSR08_06620	COG1960	acyl-CoA dehydrogenase activity
BSR08_06630	COG1649	PFAM Uncharacterised BCR, COG1649
BSR08_06645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSR08_06650	COG2027	D-alanyl-D-alanine carboxypeptidase
BSR08_06655	COG2017	converts alpha-aldose to the beta-anomer
BSR08_06660	COG0534	Mate efflux family protein
BSR08_06675	COG2801	Transposase and inactivated derivatives
BSR08_06685	COG0582	viral genome integration into host DNA
BSR08_06690	COG0166	Belongs to the GPI family
BSR08_06695	COG0405	Gamma-glutamyltransferase
BSR08_06700	COG0583	DNA-binding transcription factor activity
BSR08_06705	COG0604	alcohol dehydrogenase
BSR08_06710	COG0493	'glutamate synthase
BSR08_06715	COG0067	glutamate synthase
BSR08_06715	COG0070	glutamate synthase
BSR08_06715	COG0069	glutamate synthase activity
BSR08_06720	COG0583	DNA-binding transcription factor activity
BSR08_06745	COG0300	oxidoreductase activity
BSR08_06750	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BSR08_06760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSR08_06775	COG1131	(ABC) transporter
BSR08_06785	COG2814	Major facilitator Superfamily
BSR08_06790	COG3328	transposase activity
BSR08_06815	COG2801	Transposase and inactivated derivatives
BSR08_06835	COG3328	transposase activity
BSR08_06890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSR08_06895	COG2226	methyltransferase
BSR08_06900	COG2211	Major facilitator Superfamily
BSR08_06905	COG3328	transposase activity
BSR08_06935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSR08_06955	COG5444	nuclease activity
BSR08_06960	COG4282	regulation of fungal-type cell wall biogenesis
BSR08_06965	COG1231	oxidoreductase activity
BSR08_06970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSR08_06975	COG0662	Cupin 2, conserved barrel domain protein
BSR08_06975	COG2207	Transcriptional regulator
BSR08_06980	COG0456	acetyltransferase
BSR08_06985	COG1309	transcriptional regulator
BSR08_06990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSR08_06995	COG3708	Transcriptional regulator
BSR08_07000	COG2378	regulation of single-species biofilm formation
BSR08_07010	COG0640	Transcriptional regulator
BSR08_07015	COG0741	lytic transglycosylase activity
BSR08_07020	COG2322	membrane
BSR08_07035	COG1619	proteins homologs of microcin C7 resistance protein MccF
BSR08_07040	COG3239	Fatty acid desaturase
BSR08_07045	COG4585	Histidine kinase
BSR08_07050	COG2197	response regulator
BSR08_07055	COG3584	3D domain protein
BSR08_07055	COG1388	LysM domain
BSR08_07060	COG0514	ATP-dependent DNA helicase (RecQ)
BSR08_07075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BSR08_07080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BSR08_07095	COG0071	Belongs to the small heat shock protein (HSP20) family
BSR08_07120	COG1012	belongs to the aldehyde dehydrogenase family
BSR08_07125	COG1657	PFAM Prenyltransferase squalene oxidase
BSR08_07130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSR08_07135	COG0733	neurotransmitter:sodium symporter activity
BSR08_07140	COG0385	Bile acid
BSR08_07145	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSR08_07150	COG0567	Dehydrogenase, E1 component
BSR08_07155	COG4548	von Willebrand factor, type A
BSR08_07160	COG0714	Associated with various cellular activities
BSR08_07165	COG2032	superoxide dismutase activity
BSR08_07170	COG1388	LysM domain
BSR08_07170	COG0791	NLP P60 protein
BSR08_07175	COG1819	glycosyl
BSR08_07180	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BSR08_07185	COG0534	Mate efflux family protein
BSR08_07190	COG1366	Belongs to the anti-sigma-factor antagonist family
BSR08_07195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSR08_07200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSR08_07210	COG2962	Rard protein
BSR08_07230	COG1942	4-Oxalocrotonate Tautomerase
BSR08_07235	COG1733	regulation of RNA biosynthetic process
BSR08_07240	COG0778	Nitroreductase
BSR08_07250	COG2801	Transposase and inactivated derivatives
BSR08_07255	COG0400	carboxylic ester hydrolase activity
BSR08_07270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSR08_07275	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_07275	COG0793	Belongs to the peptidase S41A family
BSR08_07280	COG2226	methyltransferase
BSR08_07290	COG1876	peptidase activity
BSR08_07295	COG0813	purine-nucleoside phosphorylase activity
BSR08_07310	COG0671	phosphoesterase, PA-phosphatase related
BSR08_07335	COG4479	Belongs to the UPF0346 family
BSR08_07345	COG1509	lysine 2,3-aminomutase activity
BSR08_07350	COG0456	acetyltransferase
BSR08_07355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSR08_07360	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BSR08_07365	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BSR08_07370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSR08_07385	COG0456	acetyltransferase
BSR08_07390	COG0463	Glycosyl transferase, family 2
BSR08_07405	COG4641	Protein conserved in bacteria
BSR08_07410	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BSR08_07415	COG1086	Polysaccharide biosynthesis protein
BSR08_07420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSR08_07425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSR08_07430	COG1846	Transcriptional regulator
BSR08_07435	COG0534	Mate efflux family protein
BSR08_07445	COG4698	Protein conserved in bacteria
BSR08_07450	COG2755	lipolytic protein G-D-S-L family
BSR08_07455	COG1999	signal sequence binding
BSR08_07470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSR08_07475	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BSR08_07480	COG1272	protein, Hemolysin III
BSR08_07485	COG0204	Acyl-transferase
BSR08_07490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BSR08_07495	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BSR08_07505	COG2136	Putative SAM-dependent methyltransferase
BSR08_07505	COG2521	methyltransferase
BSR08_07515	COG0129	dihydroxy-acid dehydratase activity
BSR08_07520	COG1413	lyase activity
BSR08_07525	COG1418	mRNA catabolic process
BSR08_07530	COG0386	Belongs to the glutathione peroxidase family
BSR08_07535	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BSR08_07540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSR08_07545	COG1278	Cold shock
BSR08_07565	COG0328	RNA-DNA hybrid ribonuclease activity
BSR08_07570	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BSR08_07575	COG0328	RNA-DNA hybrid ribonuclease activity
BSR08_07585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSR08_07605	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BSR08_07615	COG1755	Isoprenylcysteine carboxyl methyltransferase
BSR08_07620	COG3424	synthase
BSR08_07625	COG2233	PERMEase
BSR08_07630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSR08_07635	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BSR08_07645	COG0800	Aldolase
BSR08_07650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSR08_07655	COG1609	Transcriptional regulator
BSR08_07660	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BSR08_07665	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_07670	COG1199	ATP-dependent helicase activity
BSR08_07685	COG0116	Belongs to the methyltransferase superfamily
BSR08_07700	COG4474	Belongs to the UPF0398 family
BSR08_07715	COG3359	exonuclease
BSR08_07720	COG1205	dead DEAH box helicase
BSR08_07720	COG1111	helicase
BSR08_07725	COG2190	(PTS) system
BSR08_07730	COG0071	Belongs to the small heat shock protein (HSP20) family
BSR08_07765	COG3331	DNA recombination
BSR08_07770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSR08_07770	COG4499	WXG100 protein secretion system (Wss), protein YukC
BSR08_07780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BSR08_07785	COG3935	DnaD domain protein
BSR08_07790	COG0017	Asparaginyl-tRNA synthetase
BSR08_07795	COG0436	Aminotransferase
BSR08_07800	COG5353	protein conserved in bacteria
BSR08_07810	COG1199	ATP-dependent helicase activity
BSR08_07810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSR08_07815	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BSR08_07820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSR08_07825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSR08_07830	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BSR08_07830	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BSR08_07835	COG0617	tRNA 3'-terminal CCA addition
BSR08_07840	COG0438	transferase activity, transferring glycosyl groups
BSR08_07845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSR08_07850	COG1803	Methylglyoxal synthase
BSR08_07855	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSR08_07860	COG1694	Mazg nucleotide pyrophosphohydrolase
BSR08_07865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSR08_07875	COG4347	Protein of unknown function (DUF1405)
BSR08_07880	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSR08_07880	COG2010	Cytochrome c
BSR08_07885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSR08_07890	COG0723	plastoquinol--plastocyanin reductase activity
BSR08_07900	COG5582	Belongs to the UPF0302 family
BSR08_07905	COG0457	Tetratricopeptide repeat
BSR08_07910	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSR08_07915	COG0287	Prephenate dehydrogenase
BSR08_07930	COG0133	tryptophan synthase activity
BSR08_07935	COG0135	phosphoribosylanthranilate isomerase activity
BSR08_07945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSR08_07950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSR08_07955	COG4401	Chorismate mutase type I
BSR08_07960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSR08_07965	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSR08_07970	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSR08_07980	COG0105	UTP biosynthetic process
BSR08_07985	COG0142	geranyltranstransferase activity
BSR08_07990	COG2226	methyltransferase
BSR08_07995	COG0142	geranyltranstransferase activity
BSR08_08005	COG0302	gtp cyclohydrolase
BSR08_08010	COG0776	regulation of translation
BSR08_08015	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BSR08_08030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSR08_08035	COG1160	GTP binding
BSR08_08060	COG1304	FMN binding
BSR08_08065	COG0539	negative regulation of cytoplasmic translation
BSR08_08070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BSR08_08080	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BSR08_08085	COG2959	enzyme of heme biosynthesis
BSR08_08090	COG3773	Cell wall hydrolase
BSR08_08090	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_08095	COG2339	peptidase activity
BSR08_08100	COG0492	ferredoxin-NADP+ reductase activity
BSR08_08105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSR08_08110	COG4862	establishment of competence for transformation
BSR08_08115	COG1408	metallophosphoesterase
BSR08_08125	COG1388	LysM domain
BSR08_08130	COG1266	CAAX protease self-immunity
BSR08_08135	COG0514	ATP-dependent DNA helicase (RecQ)
BSR08_08140	COG4955	Helix-turn-helix domain
BSR08_08145	COG1141	Ferredoxin
BSR08_08150	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BSR08_08155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSR08_08160	COG0710	3-dehydroquinate dehydratase activity
BSR08_08170	COG1595	DNA-templated transcription, initiation
BSR08_08175	COG5002	protein histidine kinase activity
BSR08_08180	COG0745	RESPONSE REGULATOR receiver
BSR08_08185	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSR08_08190	COG1333	cytochrome c biogenesis protein
BSR08_08195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSR08_08200	COG1187	pseudouridine synthase activity
BSR08_08205	COG0700	Nucleoside recognition
BSR08_08210	COG2715	membrane protein required for spore maturation
BSR08_08215	COG1686	Belongs to the peptidase S11 family
BSR08_08225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSR08_08230	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BSR08_08235	COG1547	Domain of unknown function (DUF309)
BSR08_08240	COG0456	acetyltransferase
BSR08_08245	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSR08_08250	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSR08_08250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSR08_08255	COG0307	riboflavin synthase, alpha
BSR08_08260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSR08_08260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSR08_08270	COG0681	Belongs to the peptidase S26 family
BSR08_08280	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BSR08_08330	COG3328	transposase activity
BSR08_08380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSR08_08390	COG4086	secreted protein
BSR08_08395	COG0019	diaminopimelate decarboxylase activity
BSR08_08400	COG0697	spore germination
BSR08_08415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSR08_08435	COG1191	sigma factor activity
BSR08_08440	COG2172	sigma factor antagonist activity
BSR08_08445	COG1366	Belongs to the anti-sigma-factor antagonist family
BSR08_08450	COG1686	Belongs to the peptidase S11 family
BSR08_08455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BSR08_08460	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BSR08_08465	COG4974	Belongs to the 'phage' integrase family
BSR08_08475	COG0735	belongs to the Fur family
BSR08_08480	COG1300	Membrane
BSR08_08490	COG0281	malic enzyme
BSR08_08495	COG1757	Na H antiporter
BSR08_08500	COG1027	Aspartate ammonia-lyase
BSR08_08505	COG0252	asparaginase activity
BSR08_08510	COG1396	sequence-specific DNA binding
BSR08_08515	COG1379	DNA repair
BSR08_08520	COG0494	nUDIX hydrolase
BSR08_08530	COG0667	Aldo Keto reductase
BSR08_08540	COG1073	alpha beta
BSR08_08550	COG4918	Iron-sulphur cluster biosynthesis
BSR08_08555	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BSR08_08555	COG0456	acetyltransferase
BSR08_08560	COG2329	Antibiotic biosynthesis monooxygenase
BSR08_08565	COG0456	acetyltransferase
BSR08_08575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSR08_08585	COG2211	Major facilitator Superfamily
BSR08_08595	COG0346	lactoylglutathione lyase activity
BSR08_08600	COG1072	(Pantothenic acid kinase))
BSR08_08605	COG3048	D-serine ammonia-lyase activity
BSR08_08610	COG0300	oxidoreductase activity
BSR08_08615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSR08_08620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSR08_08625	COG4187	Peptidase family M20/M25/M40
BSR08_08630	COG1902	pentaerythritol trinitrate reductase activity
BSR08_08645	COG0596	Alpha beta hydrolase
BSR08_08655	COG1234	tRNA 3'-trailer cleavage
BSR08_08660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BSR08_08665	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BSR08_08670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSR08_08680	COG0706	membrane insertase activity
BSR08_08685	COG3361	conserved protein (COG2071)
BSR08_08690	COG2195	Cleaves the N-terminal amino acid of tripeptides
BSR08_08700	COG0346	lactoylglutathione lyase activity
BSR08_08710	COG1376	ErfK ybiS ycfS ynhG family protein
BSR08_08715	COG4129	membrane
BSR08_08720	COG1126	abc transporter atp-binding protein
BSR08_08725	COG0765	amino acid transport
BSR08_08730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSR08_08740	COG1597	lipid kinase activity
BSR08_08750	COG0789	Transcriptional regulator
BSR08_08750	COG4978	Transcriptional regulator
BSR08_08755	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSR08_08760	COG0022	dehydrogenase e1 component
BSR08_08770	COG3426	butyrate kinase activity
BSR08_08775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSR08_08780	COG0280	phosphate acetyltransferase
BSR08_08785	COG3829	transcription factor binding
BSR08_08785	COG3290	protein histidine kinase activity
BSR08_08795	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BSR08_08800	COG2079	MmgE PrpD family protein
BSR08_08805	COG0372	Belongs to the citrate synthase family
BSR08_08810	COG1960	acyl-CoA dehydrogenase activity
BSR08_08815	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSR08_08820	COG0183	Belongs to the thiolase family
BSR08_08825	COG0584	glycerophosphoryl diester phosphodiesterase
BSR08_08830	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSR08_08845	COG1902	pentaerythritol trinitrate reductase activity
BSR08_08855	COG0745	RESPONSE REGULATOR receiver
BSR08_08865	COG0750	zinc metalloprotease
BSR08_08870	COG0497	DNA recombination
BSR08_08875	COG1438	arginine binding
BSR08_08880	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BSR08_08885	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSR08_08890	COG0142	geranyltranstransferase activity
BSR08_08895	COG1722	exodeoxyribonuclease VII activity
BSR08_08900	COG1570	exodeoxyribonuclease VII activity
BSR08_08905	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSR08_08910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSR08_08915	COG1302	Protein conserved in bacteria
BSR08_08920	COG0439	Biotin carboxylase
BSR08_08925	COG0511	ligase activity, forming carbon-carbon bonds
BSR08_08970	COG3854	ATPases associated with a variety of cellular activities
BSR08_08980	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSR08_08985	COG0006	proline dipeptidase activity
BSR08_08990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BSR08_09000	COG3872	metal-dependent enzyme
BSR08_09010	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSR08_09015	COG1321	iron dependent repressor
BSR08_09020	COG0095	Lipoate-protein ligase
BSR08_09025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSR08_09030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSR08_09035	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSR08_09040	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSR08_09045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSR08_09060	COG1396	sequence-specific DNA binding
BSR08_09070	COG0681	Belongs to the peptidase S26 family
BSR08_09095	COG4940	Competence protein ComGF
BSR08_09105	COG4970	Tfp pilus assembly protein FimT
BSR08_09110	COG4537	Required for transformation and DNA binding
BSR08_09115	COG1459	type II secretion system
BSR08_09120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSR08_09130	COG0517	IMP dehydrogenase activity
BSR08_09135	COG0598	Magnesium transport protein CorA
BSR08_09140	COG1253	flavin adenine dinucleotide binding
BSR08_09145	COG1366	Belongs to the anti-sigma-factor antagonist family
BSR08_09155	COG1393	Belongs to the ArsC family
BSR08_09165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSR08_09175	COG0011	TIGRFAM Protein of
BSR08_09185	COG2866	Carboxypeptidase
BSR08_09190	COG1368	sulfuric ester hydrolase activity
BSR08_09195	COG1940	carbohydrate kinase activity
BSR08_09200	COG4483	Protein conserved in bacteria
BSR08_09205	COG0705	Rhomboid family
BSR08_09205	COG0457	Tetratricopeptide repeat
BSR08_09215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSR08_09220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSR08_09225	COG0438	transferase activity, transferring glycosyl groups
BSR08_09240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSR08_09245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSR08_09250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSR08_09255	COG0581	inorganic phosphate transmembrane transporter activity
BSR08_09260	COG0573	inorganic phosphate transmembrane transporter activity
BSR08_09265	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BSR08_09275	COG0477	Major facilitator Superfamily
BSR08_09280	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSR08_09285	COG2839	Protein conserved in bacteria
BSR08_09290	COG5521	maltodextrose utilization protein MalA
BSR08_09295	COG1388	LysM domain
BSR08_09300	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSR08_09305	COG4709	membrane
BSR08_09310	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BSR08_09315	COG0735	belongs to the Fur family
BSR08_09320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSR08_09330	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BSR08_09335	COG0513	Belongs to the DEAD box helicase family
BSR08_09345	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSR08_09350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BSR08_09355	COG2384	SAM-dependent methyltransferase
BSR08_09360	COG2010	Cytochrome c
BSR08_09370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSR08_09375	COG0358	DNA primase activity
BSR08_09380	COG1671	Belongs to the UPF0178 family
BSR08_09385	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BSR08_09390	COG0517	IMP dehydrogenase activity
BSR08_09395	COG0751	glycine-tRNA ligase activity
BSR08_09400	COG0752	glycyl-tRNA synthetase alpha subunit
BSR08_09405	COG1381	Involved in DNA repair and RecF pathway recombination
BSR08_09415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BSR08_09420	COG0295	cytidine deaminase activity
BSR08_09425	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BSR08_09430	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BSR08_09435	COG1480	7TM receptor with intracellular HD hydrolase
BSR08_09445	COG1702	phosphate starvation-inducible protein PhoH
BSR08_09450	COG0561	phosphatase activity
BSR08_09465	COG4864	UPF0365 protein
BSR08_09470	COG1030	water channel activity
BSR08_09475	COG1610	YqeY-like protein
BSR08_09480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BSR08_09485	COG1283	sodium-dependent phosphate transmembrane transporter activity
BSR08_09490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSR08_09495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BSR08_09500	COG2264	protein methyltransferase activity
BSR08_09505	COG0484	heat shock protein binding
BSR08_09510	COG0443	Heat shock 70 kDa protein
BSR08_09515	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BSR08_09520	COG1420	regulation of RNA biosynthetic process
BSR08_09525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSR08_09530	COG0481	GTPase activity
BSR08_09540	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSR08_09545	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BSR08_09550	COG0268	Binds directly to 16S ribosomal RNA
BSR08_09555	COG1466	dna polymerase III delta subunit
BSR08_09565	COG0658	competence protein
BSR08_09565	COG2333	competence protein COMEC
BSR08_09570	COG2131	deaminase
BSR08_09575	COG1555	photosystem II stabilization
BSR08_09575	COG1596	polysaccharide export
BSR08_09580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSR08_09585	COG2226	methyltransferase
BSR08_09590	COG0799	negative regulation of ribosome biogenesis
BSR08_09595	COG1713	HD superfamily hydrolase involved in NAD metabolism
BSR08_09600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSR08_09605	COG1534	Rna-binding protein
BSR08_09610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSR08_09615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BSR08_09620	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BSR08_09635	COG2755	lipolytic protein G-D-S-L family
BSR08_09640	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_09640	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSR08_09645	COG0398	Pfam SNARE associated Golgi protein
BSR08_09650	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BSR08_09660	COG3209	COG3209 Rhs family protein
BSR08_09680	COG0114	fumarate hydratase activity
BSR08_09685	COG0583	DNA-binding transcription factor activity
BSR08_09700	COG0457	Tetratricopeptide repeat
BSR08_09820	COG0789	Transcriptional regulator
BSR08_09820	COG4978	Transcriptional regulator
BSR08_09825	COG2814	Major facilitator Superfamily
BSR08_09830	COG0456	acetyltransferase
BSR08_09835	COG1253	flavin adenine dinucleotide binding
BSR08_09845	COG0697	spore germination
BSR08_09850	COG0583	DNA-binding transcription factor activity
BSR08_09855	COG2072	flavoprotein involved in K transport
BSR08_09860	COG1230	cation diffusion facilitator family transporter
BSR08_09870	COG1114	Component of the transport system for branched-chain amino acids
BSR08_09875	COG1687	branched-chain amino acid
BSR08_09885	COG1522	sequence-specific DNA binding
BSR08_09890	COG2732	(Barnase) inhibitor
BSR08_09895	COG2124	cytochrome p450
BSR08_09910	COG1335	isochorismatase
BSR08_09920	COG2318	DinB family
BSR08_09930	COG2070	2-Nitropropane dioxygenase
BSR08_09945	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSR08_09965	COG3443	Belongs to the bacterial solute-binding protein 9 family
BSR08_09970	COG1595	DNA-templated transcription, initiation
BSR08_09975	COG0667	Aldo Keto reductase
BSR08_09980	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_09985	COG5566	PFAM Mor transcription activator
BSR08_09990	COG0596	Alpha beta hydrolase
BSR08_09995	COG4991	sh3 domain protein
BSR08_10000	COG4991	sh3 domain protein
BSR08_10005	COG0346	lactoylglutathione lyase activity
BSR08_10015	COG5577	PFAM Coat F domain
BSR08_10020	COG1063	alcohol dehydrogenase
BSR08_10030	COG5577	PFAM Coat F domain
BSR08_10035	COG0789	Transcriptional regulator
BSR08_10045	COG1064	alcohol dehydrogenase
BSR08_10050	COG0693	protein deglycase activity
BSR08_10055	COG1621	beta-fructofuranosidase activity
BSR08_10060	COG3716	PTS system mannose fructose sorbose family IID component
BSR08_10065	COG3715	PTS system
BSR08_10070	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSR08_10075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSR08_10080	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BSR08_10080	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BSR08_10085	COG1113	amino acid transport
BSR08_10090	COG1280	lysine exporter protein (LysE YggA)
BSR08_10095	COG1378	Sugar-specific transcriptional regulator TrmB
BSR08_10100	COG1595	DNA-templated transcription, initiation
BSR08_10125	COG1309	transcriptional regulator
BSR08_10130	COG2226	methyltransferase
BSR08_10140	COG2116	formate transmembrane transporter activity
BSR08_10145	COG5609	conserved protein (DUF2294)
BSR08_10150	COG3383	formate dehydrogenase (NAD+) activity
BSR08_10155	COG2427	Protein of unknown function (DUF1641)
BSR08_10170	COG0626	cystathionine gamma-synthase activity
BSR08_10175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSR08_10180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSR08_10185	COG2226	methyltransferase
BSR08_10200	COG0768	penicillin binding
BSR08_10205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSR08_10210	COG0572	uridine kinase
BSR08_10230	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSR08_10235	COG3906	Belongs to the UPF0473 family
BSR08_10240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSR08_10245	COG4472	Bacterial protein of unknown function (DUF965)
BSR08_10250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSR08_10255	COG0628	permease
BSR08_10260	COG1126	abc transporter atp-binding protein
BSR08_10265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSR08_10270	COG0765	amino acid transport
BSR08_10275	COG0765	amino acid transport
BSR08_10290	COG3881	PFAM PRC-barrel domain
BSR08_10295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSR08_10300	COG0457	Tetratricopeptide repeat
BSR08_10305	COG0482	sulfurtransferase activity
BSR08_10310	COG1104	cysteine desulfurase activity
BSR08_10315	COG1959	2 iron, 2 sulfur cluster binding
BSR08_10320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSR08_10325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BSR08_10335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSR08_10340	COG0124	histidyl-tRNA synthetase
BSR08_10350	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSR08_10350	COG4991	sh3 domain protein
BSR08_10350	COG3103	Sh3 type 3 domain protein
BSR08_10360	COG1490	D-aminoacyl-tRNA deacylase activity
BSR08_10365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSR08_10370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSR08_10375	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BSR08_10375	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BSR08_10380	COG5416	Lipopolysaccharide assembly protein A domain
BSR08_10385	COG0490	domain, Protein
BSR08_10390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSR08_10390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSR08_10400	COG2244	polysaccharide biosynthetic process
BSR08_10405	COG2323	membrane
BSR08_10415	COG1862	Preprotein translocase
BSR08_10420	COG0343	queuine tRNA-ribosyltransferase activity
BSR08_10425	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BSR08_10435	COG2255	four-way junction helicase activity
BSR08_10440	COG0632	four-way junction helicase activity
BSR08_10450	COG2814	Major facilitator Superfamily
BSR08_10455	COG0673	inositol 2-dehydrogenase activity
BSR08_10460	COG2112	serine threonine protein kinase
BSR08_10480	COG1115	amino acid carrier protein
BSR08_10485	COG0217	transcriptional regulatory protein
BSR08_10495	COG1388	LysM domain
BSR08_10500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BSR08_10505	COG0157	Belongs to the NadC ModD family
BSR08_10510	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BSR08_10515	COG1104	cysteine desulfurase activity
BSR08_10520	COG1827	regulation of RNA biosynthetic process
BSR08_10525	COG0077	Prephenate dehydratase
BSR08_10530	COG4492	Belongs to the UPF0735 family
BSR08_10535	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BSR08_10540	COG3290	protein histidine kinase activity
BSR08_10545	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSR08_10550	COG2868	ribosomal protein
BSR08_10555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSR08_10560	COG1994	Peptidase M50
BSR08_10565	COG0739	heme binding
BSR08_10570	COG2894	cell division
BSR08_10575	COG0850	regulation of cytokinetic process
BSR08_10580	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BSR08_10585	COG1792	Involved in formation and maintenance of cell shape
BSR08_10590	COG1077	Cell shape determining protein MreB Mrl
BSR08_10595	COG2003	Belongs to the UPF0758 family
BSR08_10600	COG0424	maF-like protein
BSR08_10610	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BSR08_10615	COG0285	dihydrofolate synthase activity
BSR08_10620	COG0525	valine-tRNA ligase activity
BSR08_10630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSR08_10635	COG1388	LysM domain
BSR08_10640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BSR08_10645	COG0113	porphobilinogen synthase activity
BSR08_10650	COG1587	Uroporphyrinogen-III synthase
BSR08_10655	COG0181	hydroxymethylbilane synthase activity
BSR08_10660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSR08_10665	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BSR08_10675	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BSR08_10680	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSR08_10685	COG0470	DNA polymerase III
BSR08_10685	COG1067	ATP-dependent peptidase activity
BSR08_10690	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSR08_10695	COG0544	peptidyl-prolyl cis-trans isomerase activity
BSR08_10700	COG0457	Tetratricopeptide repeat
BSR08_10700	COG1477	protein flavinylation
BSR08_10705	COG0066	3-isopropylmalate dehydratase activity
BSR08_10710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSR08_10715	COG0473	3-isopropylmalate dehydrogenase activity
BSR08_10720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSR08_10725	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSR08_10730	COG0440	acetolactate synthase activity
BSR08_10735	COG0028	Belongs to the TPP enzyme family
BSR08_10745	COG0454	-acetyltransferase
BSR08_10755	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BSR08_10765	COG2801	Transposase and inactivated derivatives
BSR08_10790	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BSR08_10815	COG0622	Phosphoesterase
BSR08_10820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSR08_10825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BSR08_10830	COG5401	PFAM Sporulation and spore germination
BSR08_10835	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSR08_10840	COG1846	Transcriptional regulator
BSR08_10845	COG2197	response regulator
BSR08_10850	COG0824	Thioesterase
BSR08_10855	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BSR08_10860	COG1053	succinate dehydrogenase
BSR08_10865	COG2009	succinate dehydrogenase
BSR08_10875	COG1719	4-vinyl reductase, 4VR
BSR08_10880	COG0527	aspartate kinase activity
BSR08_10890	COG0322	excinuclease ABC activity
BSR08_10895	COG3118	belongs to the thioredoxin family
BSR08_10900	COG3534	alpha-L-arabinofuranosidase
BSR08_10905	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BSR08_10910	COG2086	electron transfer activity
BSR08_10915	COG1024	Enoyl-CoA hydratase
BSR08_10920	COG1309	transcriptional regulator
BSR08_10925	COG0318	PFAM AMP-dependent synthetase and ligase
BSR08_10930	COG3766	membrane
BSR08_10935	COG1193	negative regulation of DNA recombination
BSR08_10940	COG1796	DNA polymerase
BSR08_10940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BSR08_10945	COG1286	toxin biosynthetic process
BSR08_10950	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BSR08_10955	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSR08_10960	COG0072	phenylalanine-tRNA ligase activity
BSR08_10960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSR08_10965	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BSR08_10975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSR08_10985	COG3835	regulator
BSR08_10990	COG0277	FAD linked oxidase domain protein
BSR08_10995	COG0247	lactate metabolic process
BSR08_11000	COG0346	lactoylglutathione lyase activity
BSR08_11005	COG1966	Carbon starvation protein
BSR08_11010	COG3534	alpha-L-arabinofuranosidase
BSR08_11015	COG0395	ABC-type sugar transport system, permease component
BSR08_11020	COG1175	transmembrane transport
BSR08_11025	COG1653	transport
BSR08_11030	COG0371	Dehydrogenase
BSR08_11035	COG0647	UMP catabolic process
BSR08_11040	COG0235	Class ii aldolase
BSR08_11045	COG1069	ribulokinase activity
BSR08_11050	COG2160	L-arabinose isomerase activity
BSR08_11060	COG1363	Peptidase, m42
BSR08_11070	COG3326	Membrane
BSR08_11075	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSR08_11080	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BSR08_11085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSR08_11095	COG1346	cytolysis
BSR08_11100	COG1380	Effector of murein hydrolase LrgA
BSR08_11105	COG3279	Response regulator of the LytR AlgR family
BSR08_11110	COG3275	phosphorelay sensor kinase activity
BSR08_11120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSR08_11130	COG0398	Pfam SNARE associated Golgi protein
BSR08_11135	COG1484	DNA-dependent DNA replication
BSR08_11140	COG3611	Membrane attachment protein
BSR08_11145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSR08_11150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BSR08_11155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSR08_11160	COG1733	regulation of RNA biosynthetic process
BSR08_11165	COG2814	Major facilitator Superfamily
BSR08_11170	COG0656	L-ascorbic acid biosynthetic process
BSR08_11175	COG0237	dephospho-CoA kinase activity
BSR08_11180	COG1971	Probably functions as a manganese efflux pump
BSR08_11185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSR08_11190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSR08_11190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSR08_11195	COG5002	protein histidine kinase activity
BSR08_11200	COG0745	RESPONSE REGULATOR receiver
BSR08_11205	COG0039	L-malate dehydrogenase activity
BSR08_11210	COG0538	isocitrate dehydrogenase activity
BSR08_11215	COG0372	Belongs to the citrate synthase family
BSR08_11220	COG2707	UPF0756 membrane protein
BSR08_11225	COG0628	permease
BSR08_11230	COG3030	protein affecting phage T7 exclusion by the F plasmid
BSR08_11235	COG0469	pyruvate kinase activity
BSR08_11240	COG0205	6-phosphofructokinase activity
BSR08_11245	COG0825	malonyl-CoA metabolic process
BSR08_11250	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BSR08_11255	COG0281	malic enzyme
BSR08_11260	COG0587	DNA-directed DNA polymerase activity
BSR08_11280	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BSR08_11290	COG4109	DRTGG domain
BSR08_11300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BSR08_11305	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_11315	COG0165	Argininosuccinate lyase
BSR08_11320	COG0137	argininosuccinate synthase activity
BSR08_11325	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSR08_11330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BSR08_11340	COG0827	DNA restriction-modification system
BSR08_11345	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BSR08_11350	COG3874	Sporulation protein YtfJ
BSR08_11360	COG1714	RDD family
BSR08_11365	COG0616	signal peptide processing
BSR08_11370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSR08_11375	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BSR08_11380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSR08_11390	COG0301	tRNA thio-modification
BSR08_11395	COG1104	cysteine desulfurase activity
BSR08_11400	COG1114	Component of the transport system for branched-chain amino acids
BSR08_11405	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BSR08_11410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BSR08_11415	COG1309	transcriptional regulator
BSR08_11420	COG1956	GAF domain-containing protein
BSR08_11425	COG2203	Gaf domain
BSR08_11425	COG2199	diguanylate cyclase activity
BSR08_11435	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BSR08_11445	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSR08_11450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSR08_11455	COG0454	-acetyltransferase
BSR08_11460	COG0517	IMP dehydrogenase activity
BSR08_11465	COG0123	including yeast histone deacetylase and acetoin utilization protein
BSR08_11470	COG1360	Flagellar Motor Protein
BSR08_11475	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BSR08_11480	COG1609	Transcriptional regulator
BSR08_11485	COG1605	Chorismate mutase
BSR08_11485	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BSR08_11490	COG3118	belongs to the thioredoxin family
BSR08_11495	COG4980	gas vesicle protein
BSR08_11500	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BSR08_11505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSR08_11510	COG1674	ftsk spoiiie
BSR08_11515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSR08_11520	COG4848	Belongs to the UPF0354 family
BSR08_11525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSR08_11535	COG1363	Peptidase, m42
BSR08_11540	COG5584	Small secreted protein
BSR08_11545	COG0281	malic enzyme
BSR08_11550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSR08_11555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSR08_11565	COG0510	thiamine kinase activity
BSR08_11570	COG1523	belongs to the glycosyl hydrolase 13 family
BSR08_11575	COG1597	lipid kinase activity
BSR08_11585	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BSR08_11590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSR08_11595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSR08_11600	COG2252	PERMEase
BSR08_11605	COG4473	ABC transporter
BSR08_11610	COG1131	(ABC) transporter
BSR08_11615	COG1349	DNA-binding transcription factor activity
BSR08_11620	COG1187	pseudouridine synthase activity
BSR08_11625	COG2244	polysaccharide biosynthetic process
BSR08_11630	COG2081	HI0933 family
BSR08_11635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BSR08_11655	COG1653	transport
BSR08_11660	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BSR08_11665	COG4209	transmembrane transport
BSR08_11675	COG1653	transport
BSR08_11680	COG0395	ABC-type sugar transport system, permease component
BSR08_11685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSR08_11690	COG2124	cytochrome p450
BSR08_11710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSR08_11715	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BSR08_11720	COG1073	alpha beta
BSR08_11745	COG1486	melibiose metabolic process
BSR08_11750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSR08_11755	COG0495	leucyl-tRNA aminoacylation
BSR08_11765	COG2202	Pas domain
BSR08_11765	COG1366	Belongs to the anti-sigma-factor antagonist family
BSR08_11770	COG2814	Major facilitator Superfamily
BSR08_11775	COG2433	Pfam Transposase IS66
BSR08_11780	COG0577	efflux transmembrane transporter activity
BSR08_11785	COG1136	(ABC) transporter
BSR08_11790	COG2205	protein histidine kinase activity
BSR08_11795	COG0745	RESPONSE REGULATOR receiver
BSR08_11800	COG0577	efflux transmembrane transporter activity
BSR08_11805	COG1136	(ABC) transporter
BSR08_11820	COG1131	(ABC) transporter
BSR08_11825	COG1725	Transcriptional regulator
BSR08_11840	COG1242	4 iron, 4 sulfur cluster binding
BSR08_11845	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BSR08_11855	COG2267	carboxylic ester hydrolase activity
BSR08_11860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BSR08_11865	COG1113	amino acid transport
BSR08_11870	COG0367	asparagine synthase
BSR08_11875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSR08_11880	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BSR08_11890	COG1506	peptidase
BSR08_11895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSR08_11900	COG1116	anion transmembrane transporter activity
BSR08_11905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSR08_11910	COG0494	nUDIX hydrolase
BSR08_11915	COG4824	toxin secretion phage lysis holin
BSR08_11920	COG0783	Belongs to the Dps family
BSR08_11935	COG1854	S-ribosylhomocysteine lyase activity
BSR08_11940	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BSR08_11945	COG0288	reversible hydration of carbon dioxide
BSR08_11950	COG0254	rRNA binding
BSR08_11955	COG1271	oxidase subunit
BSR08_11960	COG1294	oxidase, subunit
BSR08_11970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSR08_11975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSR08_11975	COG1321	iron dependent repressor
BSR08_11980	COG1121	(ABC) transporter
BSR08_11985	COG0803	Belongs to the bacterial solute-binding protein 9 family
BSR08_11990	COG4948	Mandelate Racemase Muconate Lactonizing
BSR08_11995	COG0318	PFAM AMP-dependent synthetase and ligase
BSR08_12000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BSR08_12005	COG0596	Alpha beta hydrolase
BSR08_12010	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BSR08_12015	COG1169	isochorismate synthase
BSR08_12020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BSR08_12025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSR08_12030	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSR08_12035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSR08_12040	COG0438	transferase activity, transferring glycosyl groups
BSR08_12050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSR08_12055	COG0438	transferase activity, transferring glycosyl groups
BSR08_12060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSR08_12065	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BSR08_12070	COG0058	SHG alpha-glucan phosphorylase activity
BSR08_12075	COG0297	glycogen (starch) synthase activity
BSR08_12080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BSR08_12085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BSR08_12090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BSR08_12220	COG3859	Proton-coupled thiamine transporter YuaJ
BSR08_12225	COG1247	-acetyltransferase
BSR08_12230	COG2268	Band 7 protein
BSR08_12235	COG1585	Membrane protein implicated in regulation of membrane protease activity
BSR08_12240	COG2318	DinB family
BSR08_12250	COG1454	alcohol dehydrogenase
BSR08_12260	COG1510	regulation of RNA biosynthetic process
BSR08_12270	COG0569	domain protein
BSR08_12275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSR08_12280	COG4682	membrane
BSR08_12285	COG1705	Flagellar rod assembly protein muramidase FlgJ
BSR08_12290	COG0477	Major facilitator Superfamily
BSR08_12295	COG5553	Cysteine dioxygenase type I
BSR08_12305	COG1968	undecaprenyl-diphosphatase activity
BSR08_12310	COG0628	permease
BSR08_12315	COG0673	inositol 2-dehydrogenase activity
BSR08_12320	COG4806	L-rhamnose isomerase
BSR08_12325	COG3254	rhamnose metabolic process
BSR08_12330	COG1070	Carbohydrate kinase
BSR08_12335	COG1349	DNA-binding transcription factor activity
BSR08_12340	COG3347	Dehydrogenase
BSR08_12340	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_12355	COG0840	transmembrane signaling receptor activity
BSR08_12365	COG0840	transmembrane signaling receptor activity
BSR08_12380	COG0432	Pfam Uncharacterised protein family UPF0047
BSR08_12385	COG0366	Alpha amylase catalytic
BSR08_12390	COG1253	flavin adenine dinucleotide binding
BSR08_12395	COG2738	Putative neutral zinc metallopeptidase
BSR08_12410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSR08_12425	COG0166	Belongs to the GPI family
BSR08_12430	COG1979	alcohol dehydrogenase
BSR08_12435	COG1979	alcohol dehydrogenase
BSR08_12440	COG2155	Conserved Protein
BSR08_12445	COG1098	S1 RNA binding domain
BSR08_12450	COG0436	Aminotransferase
BSR08_12455	COG1522	sequence-specific DNA binding
BSR08_12460	COG2267	carboxylic ester hydrolase activity
BSR08_12470	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BSR08_12475	COG2205	protein histidine kinase activity
BSR08_12485	COG5018	Exonuclease
BSR08_12495	COG2814	Major facilitator Superfamily
BSR08_12500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSR08_12505	COG3011	Protein conserved in bacteria
BSR08_12515	COG3290	protein histidine kinase activity
BSR08_12520	COG4565	transcriptional regulatory protein
BSR08_12545	COG3493	citrate carrier protein
BSR08_12555	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSR08_12555	COG2111	Na H antiporter
BSR08_12560	COG2111	Na H antiporter
BSR08_12565	COG1006	Multisubunit Na H antiporter MnhC subunit
BSR08_12570	COG0651	ATP synthesis coupled electron transport
BSR08_12575	COG1863	multisubunit Na H antiporter MnhE subunit
BSR08_12580	COG2212	antiporter activity
BSR08_12585	COG1320	monovalent cation:proton antiporter activity
BSR08_12590	COG2050	protein possibly involved in aromatic compounds catabolism
BSR08_12595	COG2197	response regulator
BSR08_12600	COG4585	Histidine kinase
BSR08_12610	COG0142	geranyltranstransferase activity
BSR08_12625	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BSR08_12630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BSR08_12635	COG1335	isochorismatase
BSR08_12640	COG5506	Protein of unknown function (DUF1694)
BSR08_12655	COG0628	permease
BSR08_12670	COG1418	mRNA catabolic process
BSR08_12675	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_12685	COG1511	domain protein
BSR08_12690	COG0433	COG0433 Predicted ATPase
BSR08_12690	COG1674	ftsk spoiiie
BSR08_12695	COG4499	WXG100 protein secretion system (Wss), protein YukC
BSR08_12700	COG5417	Belongs to the EsaB family
BSR08_12705	COG4842	Belongs to the WXG100 family
BSR08_12715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BSR08_12715	COG2508	Transcriptional regulator
BSR08_12720	COG0686	Belongs to the AlaDH PNT family
BSR08_12725	COG5634	Uncharacterized conserved protein (DUF2278)
BSR08_12730	COG3251	PFAM MbtH domain protein
BSR08_12735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSR08_12740	COG1535	isochorismatase
BSR08_12740	COG3433	isochorismatase activity
BSR08_12745	COG1021	2,3-dihydroxybenzoate-AMP ligase
BSR08_12750	COG1169	isochorismate synthase
BSR08_12755	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_12760	COG2819	hydrolase of the alpha beta superfamily
BSR08_12765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSR08_12770	COG1268	BioY protein
BSR08_12775	COG2056	Na+-H+ antiporter family
BSR08_12780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSR08_12785	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BSR08_12790	COG3584	3D domain protein
BSR08_12805	COG1252	NADH dehydrogenase
BSR08_12810	COG0492	ferredoxin-NADP+ reductase activity
BSR08_12820	COG0516	GMP reductase activity
BSR08_12825	COG2808	Putative FMN-binding domain
BSR08_12830	COG0456	acetyltransferase
BSR08_12925	COG0582	viral genome integration into host DNA
BSR08_12935	COG4974	Belongs to the 'phage' integrase family
BSR08_12940	COG0316	Belongs to the HesB IscA family
BSR08_12945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSR08_12950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BSR08_12955	COG4844	belongs to the
BSR08_12960	COG1252	NADH dehydrogenase
BSR08_12965	COG4837	Protein of unknown function (DUF1462)
BSR08_12970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BSR08_12975	COG0823	Involved in the tonB-independent uptake of proteins
BSR08_12975	COG1506	peptidase
BSR08_12975	COG4946	Tricorn protease homolog
BSR08_12980	COG0083	homoserine kinase activity
BSR08_12985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BSR08_12990	COG0460	homoserine dehydrogenase
BSR08_12995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSR08_13000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BSR08_13005	COG0647	UMP catabolic process
BSR08_13010	COG2445	Protein of unknown function DUF86
BSR08_13015	COG4470	Protein conserved in bacteria
BSR08_13025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BSR08_13030	COG0739	heme binding
BSR08_13040	COG3377	Domain of unknown function (DUF1805)
BSR08_13045	COG0737	Belongs to the 5'-nucleotidase family
BSR08_13050	COG0730	response to heat
BSR08_13055	COG1801	Protein of unknown function DUF72
BSR08_13065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSR08_13070	COG2508	Transcriptional regulator
BSR08_13075	COG2233	PERMEase
BSR08_13080	COG2233	PERMEase
BSR08_13085	COG3195	allantoin biosynthetic process
BSR08_13085	COG3648	Uricase
BSR08_13090	COG2351	hydroxyisourate hydrolase activity
BSR08_13100	COG2080	2 iron, 2 sulfur cluster binding
BSR08_13105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSR08_13110	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BSR08_13115	COG2068	MobA-Related Protein
BSR08_13120	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BSR08_13125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BSR08_13130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSR08_13140	COG2356	endonuclease I
BSR08_13145	COG3842	ATPase activity
BSR08_13150	COG2188	Transcriptional regulator
BSR08_13155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSR08_13165	COG1175	transmembrane transport
BSR08_13170	COG1653	transport
BSR08_13175	COG2222	sugar isomerase
BSR08_13180	COG0322	excinuclease ABC activity
BSR08_13185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSR08_13200	COG0346	lactoylglutathione lyase activity
BSR08_13205	COG0640	Transcriptional regulator
BSR08_13210	COG0719	Fe-S assembly protein
BSR08_13215	COG0822	iron-sulfur transferase activity
BSR08_13220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSR08_13225	COG0719	Fe-S assembly protein
BSR08_13230	COG0396	ATPase activity
BSR08_13250	COG1464	Belongs to the NlpA lipoprotein family
BSR08_13255	COG2011	ABC-type metal ion transport system permease component
BSR08_13260	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BSR08_13270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSR08_13275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BSR08_13285	COG0509	glycine decarboxylation via glycine cleavage system
BSR08_13290	COG1393	Belongs to the ArsC family
BSR08_13295	COG1960	acyl-CoA dehydrogenase activity
BSR08_13300	COG0183	Belongs to the thiolase family
BSR08_13305	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSR08_13305	COG1024	Enoyl-CoA hydratase
BSR08_13325	COG5577	PFAM Coat F domain
BSR08_13330	COG1846	Transcriptional regulator
BSR08_13335	COG0477	Major facilitator Superfamily
BSR08_13340	COG1942	4-Oxalocrotonate Tautomerase
BSR08_13345	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_13350	COG0583	DNA-binding transcription factor activity
BSR08_13360	COG1120	ATPase activity
BSR08_13380	COG1131	(ABC) transporter
BSR08_13430	COG0783	Belongs to the Dps family
BSR08_13435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSR08_13440	COG0745	RESPONSE REGULATOR receiver
BSR08_13445	COG2205	protein histidine kinase activity
BSR08_13445	COG2770	Histidine kinase
BSR08_13455	COG1309	transcriptional regulator
BSR08_13460	COG0114	fumarate hydratase activity
BSR08_13470	COG0697	spore germination
BSR08_13475	COG0814	amino acid
BSR08_13485	COG2197	response regulator
BSR08_13490	COG4585	Histidine kinase
BSR08_13495	COG4758	membrane
BSR08_13500	COG3595	metallopeptidase activity
BSR08_13505	COG1842	Phage shock protein A
BSR08_13510	COG4758	membrane
BSR08_13515	COG2814	Major facilitator Superfamily
BSR08_13520	COG2096	Adenosyltransferase
BSR08_13525	COG1120	ATPase activity
BSR08_13530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSR08_13535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSR08_13540	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_13545	COG3386	PFAM SMP-30 Gluconolaconase
BSR08_13550	COG2205	protein histidine kinase activity
BSR08_13555	COG0745	RESPONSE REGULATOR receiver
BSR08_13575	COG2140	Oxalate decarboxylase
BSR08_13585	COG0577	efflux transmembrane transporter activity
BSR08_13590	COG1136	(ABC) transporter
BSR08_13595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSR08_13600	COG1120	ATPase activity
BSR08_13605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSR08_13610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSR08_13615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSR08_13625	COG0531	amino acid
BSR08_13640	COG1988	membrane-bound metal-dependent
BSR08_13645	COG1368	sulfuric ester hydrolase activity
BSR08_13650	COG1910	domain protein
BSR08_13655	COG0725	ABC transporter, periplasmic molybdate-binding protein
BSR08_13660	COG4149	molybdate abc transporter
BSR08_13665	COG0656	L-ascorbic acid biosynthetic process
BSR08_13675	COG0025	NhaP-type Na H and K H
BSR08_13680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSR08_13685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BSR08_13690	COG3973	AAA domain
BSR08_13700	COG2860	membrane
BSR08_13705	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BSR08_13710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSR08_13715	COG2217	Heavy metal translocating P-type atpase
BSR08_13720	COG2217	Heavy metal translocating P-type atpase
BSR08_13725	COG2608	mercury ion transmembrane transporter activity
BSR08_13730	COG1937	Protein conserved in bacteria
BSR08_13735	COG0673	inositol 2-dehydrogenase activity
BSR08_13745	COG1289	transmembrane transporter activity
BSR08_13755	COG2076	Multidrug Resistance protein
BSR08_13760	COG1309	transcriptional regulator
BSR08_13765	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_13775	COG5444	nuclease activity
BSR08_13790	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_13790	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSR08_13795	COG4824	toxin secretion phage lysis holin
BSR08_13820	COG1705	Flagellar rod assembly protein muramidase FlgJ
BSR08_13820	COG3942	CHAP domain
BSR08_14045	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BSR08_14050	COG0557	exoribonuclease II activity
BSR08_14055	COG1647	Serine aminopeptidase, S33
BSR08_14060	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSR08_14065	COG0596	Alpha beta hydrolase
BSR08_14070	COG1476	TRANSCRIPTIONal
BSR08_14075	COG1396	sequence-specific DNA binding
BSR08_14080	COG1396	sequence-specific DNA binding
BSR08_14085	COG1733	regulation of RNA biosynthetic process
BSR08_14090	COG0840	transmembrane signaling receptor activity
BSR08_14095	COG1174	glycine betaine transport
BSR08_14100	COG1732	Glycine betaine
BSR08_14105	COG1174	glycine betaine transport
BSR08_14110	COG1125	glycine betaine transport
BSR08_14110	COG0517	IMP dehydrogenase activity
BSR08_14115	COG1510	regulation of RNA biosynthetic process
BSR08_14120	COG1174	glycine betaine transport
BSR08_14125	COG1732	Glycine betaine
BSR08_14130	COG1174	glycine betaine transport
BSR08_14135	COG1125	glycine betaine transport
BSR08_14135	COG0517	IMP dehydrogenase activity
BSR08_14140	COG1510	regulation of RNA biosynthetic process
BSR08_14145	COG2095	MarC family integral membrane protein
BSR08_14155	COG3064	Membrane
BSR08_14160	COG4640	response to antibiotic
BSR08_14165	COG0456	acetyltransferase
BSR08_14170	COG0148	phosphopyruvate hydratase activity
BSR08_14175	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BSR08_14180	COG0149	triose-phosphate isomerase activity
BSR08_14185	COG0126	phosphoglycerate kinase activity
BSR08_14195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSR08_14200	COG2390	Transcriptional regulator
BSR08_14205	COG2814	Major facilitator Superfamily
BSR08_14210	COG1609	Transcriptional regulator
BSR08_14215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSR08_14225	COG0583	DNA-binding transcription factor activity
BSR08_14230	COG0697	spore germination
BSR08_14235	COG1113	amino acid transport
BSR08_14245	COG1556	Lactate utilization protein
BSR08_14250	COG1139	Iron-sulfur cluster binding protein
BSR08_14255	COG0247	lactate metabolic process
BSR08_14260	COG2197	response regulator
BSR08_14265	COG4585	Histidine kinase
BSR08_14270	COG0842	Transport permease protein
BSR08_14275	COG1131	(ABC) transporter
BSR08_14295	COG0596	Alpha beta hydrolase
BSR08_14300	COG2208	phosphoserine phosphatase activity
BSR08_14305	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BSR08_14310	COG1874	Beta-galactosidase
BSR08_14315	COG3833	ABC-type maltose transport systems, permease component
BSR08_14320	COG1175	transmembrane transport
BSR08_14325	COG2182	Extracellular solute-binding protein
BSR08_14330	COG1609	Transcriptional regulator
BSR08_14335	COG2186	Transcriptional regulator
BSR08_14340	COG1620	l-lactate permease
BSR08_14345	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BSR08_14355	COG5039	Polysaccharide pyruvyl transferase
BSR08_14360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSR08_14365	COG0110	maltose O-acetyltransferase activity
BSR08_14370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSR08_14375	COG2244	polysaccharide biosynthetic process
BSR08_14380	COG1216	Glycosyl transferase, family 2
BSR08_14385	COG5039	Polysaccharide pyruvyl transferase
BSR08_14390	COG1216	Glycosyl transferase, family 2
BSR08_14400	COG0438	transferase activity, transferring glycosyl groups
BSR08_14405	COG1215	transferase activity, transferring glycosyl groups
BSR08_14410	COG0438	transferase activity, transferring glycosyl groups
BSR08_14415	COG1086	Polysaccharide biosynthesis protein
BSR08_14420	COG0489	protein tyrosine kinase activity
BSR08_14425	COG3944	biosynthesis protein
BSR08_14430	COG1396	sequence-specific DNA binding
BSR08_14435	COG2272	Belongs to the type-B carboxylesterase lipase family
BSR08_14445	COG3479	Phenolic acid decarboxylase
BSR08_14460	COG1794	racemase activity, acting on amino acids and derivatives
BSR08_14470	COG1621	beta-fructofuranosidase activity
BSR08_14475	COG1621	beta-fructofuranosidase activity
BSR08_14480	COG0531	amino acid
BSR08_14485	COG1309	transcriptional regulator
BSR08_14490	COG2076	Multidrug Resistance protein
BSR08_14495	COG2076	Multidrug Resistance protein
BSR08_14515	COG1674	ftsk spoiiie
BSR08_14535	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSR08_14535	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_14535	COG1388	LysM domain
BSR08_14570	COG1705	Flagellar rod assembly protein muramidase FlgJ
BSR08_14650	COG0582	viral genome integration into host DNA
BSR08_14750	COG4974	Belongs to the 'phage' integrase family
BSR08_14760	COG0740	serine-type endopeptidase activity
BSR08_14765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSR08_14770	COG0366	Alpha amylase catalytic
BSR08_14775	COG1554	hydrolase, family 65, central catalytic
BSR08_14780	COG5521	maltodextrose utilization protein MalA
BSR08_14785	COG3833	ABC-type maltose transport systems, permease component
BSR08_14790	COG1175	transmembrane transport
BSR08_14795	COG2182	Extracellular solute-binding protein
BSR08_14805	COG1609	Transcriptional regulator
BSR08_14810	COG1611	Belongs to the LOG family
BSR08_14820	COG0659	secondary active sulfate transmembrane transporter activity
BSR08_14825	COG0288	reversible hydration of carbon dioxide
BSR08_14830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSR08_14835	COG0577	efflux transmembrane transporter activity
BSR08_14840	COG1136	(ABC) transporter
BSR08_14845	COG5002	protein histidine kinase activity
BSR08_14850	COG0745	RESPONSE REGULATOR receiver
BSR08_14860	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BSR08_14865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSR08_14870	COG1481	regulation of sporulation
BSR08_14875	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BSR08_14880	COG1660	Displays ATPase and GTPase activities
BSR08_14885	COG1051	belongs to the nudix hydrolase family
BSR08_14890	COG0492	ferredoxin-NADP+ reductase activity
BSR08_14895	COG3883	PFAM NLP P60 protein
BSR08_14895	COG0791	NLP P60 protein
BSR08_14900	COG0457	Tetratricopeptide repeat
BSR08_14905	COG1132	(ABC) transporter
BSR08_14925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSR08_14925	COG0140	phosphoribosyl-ATP diphosphatase activity
BSR08_14930	COG0107	imidazoleglycerol-phosphate synthase activity
BSR08_14935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSR08_14940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSR08_14945	COG0131	Imidazoleglycerol-phosphate dehydratase
BSR08_14950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSR08_14955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSR08_14960	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BSR08_14965	COG4990	cell redox homeostasis
BSR08_14970	COG5297	Belongs to the glycosyl hydrolase family 6
BSR08_14980	COG2801	Transposase and inactivated derivatives
BSR08_14990	COG0546	phosphoglycolate phosphatase activity
BSR08_14995	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BSR08_15000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSR08_15005	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BSR08_15010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BSR08_15015	COG0363	glucosamine-6-phosphate deaminase activity
BSR08_15025	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BSR08_15040	COG1950	PFAM Membrane protein of
BSR08_15045	COG1983	PspC domain protein
BSR08_15050	COG3595	metallopeptidase activity
BSR08_15065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSR08_15070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSR08_15075	COG0556	nucleotide-excision repair
BSR08_15080	COG4897	Protein conserved in bacteria
BSR08_15085	COG0574	Belongs to the PEP-utilizing enzyme family
BSR08_15085	COG3848	Pyruvate phosphate dikinase
BSR08_15090	COG1309	transcriptional regulator
BSR08_15095	COG2814	Major facilitator Superfamily
BSR08_15100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSR08_15110	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_15110	COG0793	Belongs to the peptidase S41A family
BSR08_15115	COG2177	Part of the ABC transporter FtsEX involved in
BSR08_15120	COG2884	Cell division ATP-binding protein ftsE
BSR08_15125	COG2010	Cytochrome c
BSR08_15130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSR08_15135	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BSR08_15140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BSR08_15145	COG0653	protein targeting
BSR08_15150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BSR08_15165	COG1516	flagellar protein fliS
BSR08_15170	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BSR08_15175	COG1334	flagellar protein FlaG
BSR08_15180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSR08_15185	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BSR08_15190	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BSR08_15200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSR08_15205	COG4786	Flagellar basal body rod
BSR08_15205	COG1256	bacterial-type flagellum assembly
BSR08_15210	COG3418	PFAM FlgN family protein
BSR08_15215	COG2747	anti-sigma28 factor FlgM
BSR08_15225	COG1040	competence protein
BSR08_15235	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BSR08_15240	COG1307	EDD domain protein, DegV family
BSR08_15245	COG2197	response regulator
BSR08_15250	COG4585	Histidine kinase
BSR08_15255	COG1739	Uncharacterized protein family UPF0029
BSR08_15260	COG1316	TRANSCRIPTIONal
BSR08_15295	COG1131	(ABC) transporter
BSR08_15305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSR08_15310	COG0438	transferase activity, transferring glycosyl groups
BSR08_15315	COG1215	transferase activity, transferring glycosyl groups
BSR08_15320	COG3206	protein involved in exopolysaccharide biosynthesis
BSR08_15325	COG3307	-O-antigen
BSR08_15335	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSR08_15340	COG0438	transferase activity, transferring glycosyl groups
BSR08_15340	COG0297	glycogen (starch) synthase activity
BSR08_15345	COG2244	polysaccharide biosynthetic process
BSR08_15360	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSR08_15360	COG2247	cell wall binding repeat
BSR08_15365	COG2247	cell wall binding repeat
BSR08_15365	COG2385	sporulation resulting in formation of a cellular spore
BSR08_15395	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BSR08_15400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSR08_15415	COG1134	teichoic acid transport
BSR08_15420	COG1682	transport, permease protein
BSR08_15435	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSR08_15435	COG0463	Glycosyl transferase, family 2
BSR08_15440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSR08_15445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BSR08_15450	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BSR08_15455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSR08_15460	COG4193	domain, Protein
BSR08_15465	COG1482	cell wall glycoprotein biosynthetic process
BSR08_15475	COG0697	spore germination
BSR08_15480	COG0814	amino acid
BSR08_15495	COG1316	TRANSCRIPTIONal
BSR08_15500	COG0561	phosphatase activity
BSR08_15505	COG0791	NLP P60 protein
BSR08_15515	COG2843	Capsule synthesis protein
BSR08_15525	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSR08_15535	COG1609	Transcriptional regulator
BSR08_15540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSR08_15545	COG1869	D-ribose catabolic process
BSR08_15550	COG1129	ABC transporter
BSR08_15555	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSR08_15560	COG1879	ABC-type sugar transport system periplasmic component
BSR08_15565	COG3103	Sh3 type 3 domain protein
BSR08_15575	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSR08_15580	COG3527	Alpha-acetolactate decarboxylase
BSR08_15585	COG0028	Belongs to the TPP enzyme family
BSR08_15590	COG0583	DNA-binding transcription factor activity
BSR08_15595	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BSR08_15610	COG5337	Spore coat protein CotH
BSR08_15620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSR08_15630	COG0405	Gamma-glutamyltransferase
BSR08_15635	COG1522	sequence-specific DNA binding
BSR08_15640	COG2059	Chromate
BSR08_15645	COG2059	Chromate
BSR08_15655	COG0655	NAD(P)H dehydrogenase (quinone) activity
BSR08_15660	COG0583	DNA-binding transcription factor activity
BSR08_15690	COG5444	nuclease activity
BSR08_15710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSR08_15715	COG4464	protein tyrosine phosphatase activity
BSR08_15720	COG0489	protein tyrosine kinase activity
BSR08_15725	COG3944	biosynthesis protein
BSR08_15735	COG4715	Zinc finger, swim domain protein
BSR08_15740	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSR08_15750	COG0561	phosphatase activity
BSR08_15755	COG1349	DNA-binding transcription factor activity
BSR08_15760	COG0629	single-stranded DNA binding
BSR08_15780	COG2972	Histidine kinase
BSR08_15780	COG0745	RESPONSE REGULATOR receiver
BSR08_15785	COG1970	mechanosensitive ion channel activity
BSR08_15790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSR08_15795	COG0457	Tetratricopeptide repeat
BSR08_15800	COG4786	Flagellar basal body rod
BSR08_15805	COG4786	Flagellar basal body rod
BSR08_15810	COG1077	Cell shape determining protein MreB Mrl
BSR08_15815	COG1609	Transcriptional regulator
BSR08_15825	COG1846	Transcriptional regulator
BSR08_15830	COG2814	Major facilitator Superfamily
BSR08_15835	COG3420	alginic acid biosynthetic process
BSR08_15840	COG1953	Uracil, thiamine, allantoin
BSR08_15845	COG0477	Major facilitator Superfamily
BSR08_15850	COG1335	isochorismatase
BSR08_15860	COG0004	ammonium transporteR
BSR08_15865	COG0347	Belongs to the P(II) protein family
BSR08_15870	COG0671	phosphoesterase, PA-phosphatase related
BSR08_15880	COG0739	heme binding
BSR08_15885	COG1247	-acetyltransferase
BSR08_15895	COG2089	acid synthase
BSR08_15905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSR08_15910	COG0789	Transcriptional regulator
BSR08_15920	COG2910	NAD(P)H-binding
BSR08_15925	COG1959	2 iron, 2 sulfur cluster binding
BSR08_15930	COG0804	urea catabolic process
BSR08_15935	COG0832	Belongs to the urease beta subunit family
BSR08_15940	COG0831	urea catabolic process
BSR08_15955	COG3237	CsbD-like
BSR08_15960	COG1994	Peptidase M50
BSR08_15965	COG0457	Tetratricopeptide repeat
BSR08_15975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSR08_15980	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BSR08_15990	COG2304	oxidoreductase activity
BSR08_16000	COG2304	oxidoreductase activity
BSR08_16005	COG2385	sporulation resulting in formation of a cellular spore
BSR08_16010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSR08_16020	COG4836	Membrane
BSR08_16030	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSR08_16035	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSR08_16040	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSR08_16045	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSR08_16050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSR08_16055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSR08_16065	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSR08_16070	COG0356	it plays a direct role in the translocation of protons across the membrane
BSR08_16080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BSR08_16085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSR08_16090	COG4475	Protein of unknown function (DUF436)
BSR08_16095	COG0698	ribose 5-phosphate isomerase
BSR08_16100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSR08_16105	COG1971	Probably functions as a manganese efflux pump
BSR08_16110	COG0009	L-threonylcarbamoyladenylate synthase
BSR08_16115	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BSR08_16135	COG2890	protein-(glutamine-N5) methyltransferase activity
BSR08_16140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSR08_16145	COG0346	lactoylglutathione lyase activity
BSR08_16150	COG0789	Transcriptional regulator
BSR08_16155	COG0679	Auxin Efflux Carrier
BSR08_16160	COG0281	malic enzyme
BSR08_16165	COG1435	thymidine kinase activity
BSR08_16170	COG0254	rRNA binding
BSR08_16175	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BSR08_16185	COG1494	fructose-1,6-bisphosphatase
BSR08_16190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSR08_16195	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSR08_16200	COG0191	fructose-bisphosphate aldolase activity
BSR08_16205	COG2204	response regulator
BSR08_16210	COG4821	SIS domain
BSR08_16215	COG0504	CTP synthase activity
BSR08_16220	COG3343	RNA polymerase activity
BSR08_16225	COG1960	acyl-CoA dehydrogenase activity
BSR08_16230	COG0247	lactate metabolic process
BSR08_16230	COG2181	nitrate reductase activity
BSR08_16235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSR08_16240	COG4294	response to UV
BSR08_16250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BSR08_16260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSR08_16270	COG2181	nitrate reductase activity
BSR08_16275	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BSR08_16280	COG1140	nitrate reductase beta subunit
BSR08_16285	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BSR08_16290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSR08_16300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSR08_16305	COG2223	nitrite transmembrane transporter activity
BSR08_16310	COG0018	arginyl-trna synthetase
BSR08_16315	COG4506	Protein conserved in bacteria
BSR08_16330	COG0535	radical SAM domain protein
BSR08_16340	COG1131	(ABC) transporter
BSR08_16345	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BSR08_16350	COG0612	Peptidase, M16
BSR08_16355	COG0612	Peptidase, M16
BSR08_16365	COG3391	amine dehydrogenase activity
BSR08_16370	COG3391	amine dehydrogenase activity
BSR08_16380	COG0457	Tetratricopeptide repeat
BSR08_16395	COG0010	Belongs to the arginase family
BSR08_16400	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BSR08_16405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSR08_16420	COG1994	Peptidase M50
BSR08_16425	COG1942	4-Oxalocrotonate Tautomerase
BSR08_16430	COG1846	Transcriptional regulator
BSR08_16435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSR08_16445	COG0477	Major facilitator Superfamily
BSR08_16450	COG1959	2 iron, 2 sulfur cluster binding
BSR08_16455	COG3465	dGTPase activity
BSR08_16460	COG1078	dGTPase activity
BSR08_16465	COG4844	belongs to the
BSR08_16475	COG0697	spore germination
BSR08_16480	COG0095	Lipoate-protein ligase
BSR08_16485	COG0583	DNA-binding transcription factor activity
BSR08_16490	COG0280	phosphate acetyltransferase
BSR08_16500	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_16505	COG0436	Aminotransferase
BSR08_16510	COG2814	Major facilitator Superfamily
BSR08_16515	COG0151	Belongs to the GarS family
BSR08_16520	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_16525	COG1917	Cupin 2, conserved barrel domain protein
BSR08_16530	COG0077	Prephenate dehydratase
BSR08_16535	COG2814	Major facilitator Superfamily
BSR08_16540	COG0833	amino acid
BSR08_16545	COG4187	Peptidase family M20/M25/M40
BSR08_16550	COG1012	belongs to the aldehyde dehydrogenase family
BSR08_16555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSR08_16565	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BSR08_16570	COG1091	dTDP-4-dehydrorhamnose reductase activity
BSR08_16575	COG1088	dTDP-glucose 4,6-dehydratase activity
BSR08_16580	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BSR08_16585	COG3980	spore coat polysaccharide biosynthesis protein
BSR08_16590	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BSR08_16595	COG2089	acid synthase
BSR08_16600	COG0456	acetyltransferase
BSR08_16605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSR08_16610	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSR08_16615	COG0463	Glycosyl transferase, family 2
BSR08_16630	COG2363	Small membrane protein
BSR08_16635	COG2233	PERMEase
BSR08_16645	COG1012	belongs to the aldehyde dehydrogenase family
BSR08_16650	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BSR08_16655	COG1216	Glycosyl transferase, family 2
BSR08_16660	COG0351	phosphomethylpyrimidine kinase
BSR08_16670	COG1621	beta-fructofuranosidase activity
BSR08_16675	COG1263	PTS System
BSR08_16675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSR08_16680	COG2116	formate transmembrane transporter activity
BSR08_16695	COG1404	Belongs to the peptidase S8 family
BSR08_16700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSR08_16705	COG0778	Nitroreductase
BSR08_16710	COG0772	Belongs to the SEDS family
BSR08_16725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSR08_16730	COG1845	cytochrome c oxidase, subunit III
BSR08_16735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSR08_16740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSR08_16745	COG2261	transglycosylase associated protein
BSR08_16750	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BSR08_16755	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BSR08_16760	COG2246	polysaccharide biosynthetic process
BSR08_16765	COG1309	transcriptional regulator
BSR08_16775	COG3162	membrane
BSR08_16780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSR08_16785	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BSR08_16790	COG2837	iron assimilation
BSR08_16795	COG2822	iron ion transport
BSR08_16800	COG0672	)-iron permease
BSR08_16805	COG0352	thiamine-phosphate diphosphorylase activity
BSR08_16810	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BSR08_16815	COG0583	DNA-binding transcription factor activity
BSR08_16820	COG1380	Effector of murein hydrolase LrgA
BSR08_16825	COG1346	cytolysis
BSR08_16830	COG2814	Major facilitator Superfamily
BSR08_16835	COG4895	conserved protein (DUF2196)
BSR08_16840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BSR08_16845	COG0346	lactoylglutathione lyase activity
BSR08_16860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BSR08_16870	COG1263	PTS System
BSR08_16870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSR08_16875	COG3711	transcriptional antiterminator
BSR08_16880	COG1442	glycosyl transferase family 8
BSR08_16885	COG5522	Integral membrane protein (intg_mem_TP0381)
BSR08_16890	COG1846	Transcriptional regulator
BSR08_16895	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSR08_16900	COG2234	aminopeptidase activity
BSR08_16905	COG2357	RelA SpoT domain protein
BSR08_16915	COG2801	Transposase and inactivated derivatives
BSR08_16920	COG1575	Belongs to the MenA family. Type 1 subfamily
BSR08_16940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSR08_16945	COG1696	Membrane protein involved in D-alanine export
BSR08_16950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSR08_16955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BSR08_16965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSR08_16970	COG1486	melibiose metabolic process
BSR08_16975	COG1447	Phosphotransferase system cellobiose-specific component IIA
BSR08_16980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BSR08_16985	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BSR08_16990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSR08_16990	COG3711	transcriptional antiterminator
BSR08_17000	COG2094	Belongs to the DNA glycosylase MPG family
BSR08_17005	COG0753	catalase activity
BSR08_17010	COG2814	Major facilitator Superfamily
BSR08_17015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BSR08_17020	COG1131	(ABC) transporter
BSR08_17040	COG1595	DNA-templated transcription, initiation
BSR08_17045	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BSR08_17050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSR08_17055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BSR08_17060	COG4988	ABC transporter
BSR08_17065	COG1294	oxidase, subunit
BSR08_17070	COG1271	oxidase subunit
BSR08_17075	COG3493	citrate carrier protein
BSR08_17080	COG0501	Belongs to the peptidase M48B family
BSR08_17090	COG0726	polysaccharide deacetylase
BSR08_17095	COG3842	ATPase activity
BSR08_17100	COG2508	Transcriptional regulator
BSR08_17105	COG1012	belongs to the aldehyde dehydrogenase family
BSR08_17110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSR08_17120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSR08_17130	COG4585	Histidine kinase
BSR08_17135	COG2197	response regulator
BSR08_17140	COG2195	Cleaves the N-terminal amino acid of tripeptides
BSR08_17155	COG4894	glucomannan catabolic process
BSR08_17160	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BSR08_17165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BSR08_17170	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_17175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BSR08_17180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BSR08_17185	COG2610	gluconate transmembrane transporter activity
BSR08_17195	COG0500	methyltransferase
BSR08_17200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BSR08_17215	COG0693	protein deglycase activity
BSR08_17215	COG0753	catalase activity
BSR08_17220	COG2851	Citrate transporter
BSR08_17225	COG2273	Hydrolase Family 16
BSR08_17230	COG3711	transcriptional antiterminator
BSR08_17245	COG2270	Major facilitator Superfamily
BSR08_17250	COG0513	Belongs to the DEAD box helicase family
BSR08_17255	COG3401	FG-GAP repeat protein
BSR08_17255	COG2755	lipolytic protein G-D-S-L family
BSR08_17370	COG0697	spore germination
BSR08_17385	COG0589	response to stress
BSR08_17395	COG2190	(PTS) system
BSR08_17395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSR08_17395	COG1263	PTS System
BSR08_17405	COG5444	nuclease activity
BSR08_17415	COG5444	nuclease activity
BSR08_17435	COG0494	nUDIX hydrolase
BSR08_17440	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BSR08_17445	COG3507	Belongs to the glycosyl hydrolase 43 family
BSR08_17450	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BSR08_17460	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BSR08_17465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BSR08_17470	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BSR08_17475	COG2390	Transcriptional regulator
BSR08_17485	COG3192	ethanolamine utilization protein
BSR08_17490	COG2079	MmgE PrpD family protein
BSR08_17500	COG1126	abc transporter atp-binding protein
BSR08_17505	COG0765	amino acid transport
BSR08_17510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSR08_17525	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BSR08_17530	COG0561	phosphatase activity
BSR08_17560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSR08_17565	COG5294	Protein conserved in bacteria
BSR08_17580	COG2205	protein histidine kinase activity
BSR08_17585	COG0745	RESPONSE REGULATOR receiver
BSR08_17590	COG0191	fructose-bisphosphate aldolase activity
BSR08_17595	COG1082	Xylose isomerase domain protein TIM barrel
BSR08_17600	COG1082	Xylose isomerase domain protein TIM barrel
BSR08_17605	COG0673	inositol 2-dehydrogenase activity
BSR08_17610	COG2814	Major facilitator Superfamily
BSR08_17615	COG1082	Xylose isomerase domain protein TIM barrel
BSR08_17620	COG3962	Belongs to the TPP enzyme family
BSR08_17625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSR08_17645	COG1349	DNA-binding transcription factor activity
BSR08_17650	COG0667	Aldo Keto reductase
BSR08_17680	COG0326	Molecular chaperone. Has ATPase activity
BSR08_17740	COG1917	Cupin 2, conserved barrel domain protein
BSR08_17745	COG1309	transcriptional regulator
BSR08_17750	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_17755	COG1846	Transcriptional regulator
BSR08_17760	COG1380	Effector of murein hydrolase LrgA
BSR08_17765	COG1346	cytolysis
BSR08_17770	COG5039	Polysaccharide pyruvyl transferase
BSR08_17775	COG1929	Belongs to the glycerate kinase type-1 family
BSR08_17780	COG1802	Transcriptional regulator
BSR08_17785	COG1070	Carbohydrate kinase
BSR08_17790	COG2610	gluconate transmembrane transporter activity
BSR08_17795	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BSR08_17800	COG0450	alkyl hydroperoxide reductase
BSR08_17805	COG3634	alkyl hydroperoxide reductase activity
BSR08_17810	COG2723	6-phospho-beta-galactosidase activity
BSR08_17825	COG2188	Transcriptional regulator
BSR08_17835	COG1131	(ABC) transporter
BSR08_17840	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BSR08_17855	COG0071	Belongs to the small heat shock protein (HSP20) family
BSR08_17890	COG0210	DNA helicase
BSR08_17920	COG2963	transposase activity
BSR08_17955	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BSR08_17970	COG1063	alcohol dehydrogenase
BSR08_17990	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BSR08_17995	COG0456	acetyltransferase
BSR08_18000	COG0457	Tetratricopeptide repeat
BSR08_18010	COG0010	Belongs to the arginase family
BSR08_18015	COG0833	amino acid
BSR08_18020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSR08_18040	COG5658	integral membrane protein
BSR08_18045	COG0640	Transcriptional regulator
BSR08_18050	COG3829	transcription factor binding
BSR08_18065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSR08_18070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BSR08_18075	COG4853	Protein conserved in bacteria
BSR08_18080	COG4863	YycH protein
BSR08_18085	COG5002	protein histidine kinase activity
BSR08_18090	COG0745	RESPONSE REGULATOR receiver
BSR08_18120	COG0346	lactoylglutathione lyase activity
BSR08_18125	COG0305	Participates in initiation and elongation during chromosome replication
BSR08_18145	COG3093	addiction module antidote protein HigA
BSR08_18150	COG2807	transmembrane transport
BSR08_18155	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BSR08_18160	COG0359	binds to the 23S rRNA
BSR08_18165	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BSR08_18170	COG4241	membrane
BSR08_18185	COG1733	regulation of RNA biosynthetic process
BSR08_18190	COG1227	inorganic diphosphatase activity
BSR08_18205	COG2271	Major facilitator Superfamily
BSR08_18210	COG4978	Transcriptional regulator
BSR08_18210	COG0789	Transcriptional regulator
BSR08_18220	COG4319	ketosteroid isomerase
BSR08_18225	COG1357	PFAM Pentapeptide repeats (8 copies)
BSR08_18240	COG1846	Transcriptional regulator
BSR08_18245	COG2153	protein acetylation
BSR08_18250	COG2364	Membrane
BSR08_18255	COG0456	acetyltransferase
BSR08_18260	COG2315	Protein conserved in bacteria
BSR08_18265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BSR08_18270	COG1331	Highly conserved protein containing a thioredoxin domain
BSR08_18275	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BSR08_18280	COG1331	Highly conserved protein containing a thioredoxin domain
BSR08_18285	COG1266	CAAX protease self-immunity
BSR08_18290	COG2814	Major facilitator Superfamily
BSR08_18290	COG0477	Major facilitator Superfamily
BSR08_18295	COG0346	lactoylglutathione lyase activity
BSR08_18300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSR08_18305	COG0542	response to heat
BSR08_18320	COG0708	Exodeoxyribonuclease III
BSR08_18325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSR08_18330	COG0629	single-stranded DNA binding
BSR08_18335	COG0360	Binds together with S18 to 16S ribosomal RNA
BSR08_18340	COG0012	GTP binding
BSR08_18345	COG0243	molybdopterin cofactor binding
BSR08_18350	COG4481	Protein conserved in bacteria
BSR08_18355	COG3949	Membrane
BSR08_18365	COG1475	DNA binding
BSR08_18370	COG1192	Involved in chromosome partitioning
BSR08_18380	COG1475	DNA binding
BSR08_18385	COG0357	Ribosomal RNA small subunit methyltransferase G
BSR08_18390	COG0445	tRNA wobble uridine modification
BSR08_18395	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSR08_18400	COG1847	R3H domain protein
BSR08_18405	COG0706	membrane insertase activity
BSR08_18410	COG0594	ribonuclease P activity
BSR08_18415	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BSR08_18420	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSR08_18425	COG0592	DNA-directed DNA polymerase activity
BSR08_18430	COG2501	S4 domain
BSR08_18435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSR08_18445	COG0187	DNA topoisomerase II activity
BSR08_18450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSR08_18485	COG0516	GMP reductase activity
BSR08_18485	COG0517	IMP dehydrogenase activity
BSR08_18490	COG1686	Belongs to the peptidase S11 family
BSR08_18495	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BSR08_18500	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BSR08_18505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSR08_18515	COG1428	Deoxynucleoside kinase
BSR08_18520	COG1428	Deoxynucleoside kinase
BSR08_18525	COG1388	LysM domain
BSR08_18525	COG3858	chitin binding
BSR08_18530	COG1335	isochorismatase
BSR08_18535	COG0590	tRNA wobble adenosine to inosine editing
BSR08_18545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BSR08_18550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BSR08_18555	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSR08_18600	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BSR08_18605	COG3853	Toxic anion resistance protein (TelA)
BSR08_18610	COG1982	Orn Lys Arg decarboxylase major
BSR08_18615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSR08_18620	COG3870	Protein conserved in bacteria
BSR08_18625	COG1728	Protein conserved in bacteria
BSR08_18630	COG0470	DNA polymerase III
BSR08_18635	COG1774	PSP1 C-terminal conserved region
BSR08_18640	COG4467	Involved in initiation control of chromosome replication
BSR08_18645	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BSR08_18650	COG2827	Endonuclease containing a URI domain
BSR08_18655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSR08_18660	COG2002	toxin-antitoxin pair type II binding
BSR08_18665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSR08_18665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSR08_18670	COG0084	hydrolase, TatD family'
BSR08_18675	COG3583	domain protein
BSR08_18675	COG3584	3D domain protein
BSR08_18680	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BSR08_18685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSR08_18695	COG4466	Protein conserved in bacteria
BSR08_18705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BSR08_18710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSR08_18715	COG0251	oxidation-reduction process
BSR08_18720	COG2088	sporulation resulting in formation of a cellular spore
BSR08_18730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSR08_18735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BSR08_18740	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BSR08_18745	COG0193	aminoacyl-tRNA hydrolase activity
BSR08_18755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSR08_18760	COG2002	toxin-antitoxin pair type II binding
BSR08_18765	COG2244	polysaccharide biosynthetic process
BSR08_18770	COG3956	TIGRFAM MazG family protein
BSR08_18775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BSR08_18790	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BSR08_18795	COG1098	S1 RNA binding domain
BSR08_18810	COG2208	phosphoserine phosphatase activity
BSR08_18815	COG2304	oxidoreductase activity
BSR08_18820	COG0515	serine threonine protein kinase
BSR08_18825	COG0037	tRNA processing
BSR08_18835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSR08_18840	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BSR08_18845	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BSR08_18850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSR08_18855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSR08_18860	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSR08_18865	COG0512	Glutamine amidotransferase of anthranilate synthase
BSR08_18870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSR08_18875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BSR08_18880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BSR08_18885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSR08_18890	COG1396	sequence-specific DNA binding
BSR08_18895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSR08_18900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSR08_18980	COG4463	regulation of RNA biosynthetic process
BSR08_18985	COG3880	PFAM UvrB UvrC protein
BSR08_18990	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BSR08_18995	COG0542	response to heat
BSR08_19000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BSR08_19005	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BSR08_19010	COG4956	integral membrane protein (PIN domain superfamily)
BSR08_19015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BSR08_19020	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSR08_19025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSR08_19035	COG1045	serine acetyltransferase
BSR08_19040	COG0215	cysteine-tRNA ligase activity
BSR08_19045	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BSR08_19050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSR08_19055	COG3688	RNA-binding protein containing a PIN domain
BSR08_19060	COG1595	DNA-templated transcription, initiation
BSR08_19065	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSR08_19070	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSR08_19075	COG0250	Participates in transcription elongation, termination and antitermination
BSR08_19080	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSR08_19085	COG0081	regulation of translation
BSR08_19090	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BSR08_19095	COG0222	ribosome binding
BSR08_19100	COG2813	Specifically methylates the guanine in position
BSR08_19105	COG0085	RNA polymerase activity
BSR08_19110	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSR08_19115	COG1358	cellular component organization or biogenesis
BSR08_19120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSR08_19125	COG0049	tRNA binding
BSR08_19130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSR08_19135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSR08_19140	COG0596	Alpha beta hydrolase
BSR08_19145	COG0051	transcription antitermination factor activity, RNA binding
BSR08_19150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSR08_19155	COG0088	Forms part of the polypeptide exit tunnel
BSR08_19160	COG0089	rRNA binding
BSR08_19165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSR08_19170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSR08_19175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BSR08_19180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BSR08_19185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSR08_19190	COG0255	Belongs to the universal ribosomal protein uL29 family
BSR08_19195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSR08_19200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BSR08_19210	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BSR08_19220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSR08_19225	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSR08_19230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSR08_19235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSR08_19240	COG1841	ribosomal large subunit assembly
BSR08_19245	COG0200	Binds to the 23S rRNA
BSR08_19250	COG0201	protein transport
BSR08_19255	COG0563	adenylate kinase activity
BSR08_19260	COG0024	Methionine aminopeptidase
BSR08_19265	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BSR08_19270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BSR08_19275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSR08_19280	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BSR08_19285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BSR08_19290	COG0202	RNA polymerase activity
BSR08_19295	COG0203	ribosomal protein L17
BSR08_19300	COG1122	ATPase activity
BSR08_19305	COG1122	ATPase activity
BSR08_19310	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BSR08_19315	COG0101	tRNA pseudouridine synthase activity
BSR08_19320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSR08_19325	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSR08_19335	COG2226	methyltransferase
BSR08_19345	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSR08_19350	COG0489	protein tyrosine kinase activity
BSR08_19360	COG2194	sulfuric ester hydrolase activity
BSR08_19365	COG0726	polysaccharide deacetylase
BSR08_19450	COG0659	secondary active sulfate transmembrane transporter activity
BSR08_19455	COG0385	Bile acid
BSR08_19460	COG2819	hydrolase of the alpha beta superfamily
BSR08_19465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSR08_19470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSR08_19475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSR08_19480	COG2207	Transcriptional regulator
BSR08_19480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSR08_19485	COG3876	Protein conserved in bacteria
BSR08_19490	COG1472	Belongs to the glycosyl hydrolase 3 family
BSR08_19495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSR08_19500	COG1263	PTS System
BSR08_19500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSR08_19505	COG1737	Transcriptional regulator
BSR08_19510	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BSR08_19515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSR08_19520	COG1683	Conserved Protein
BSR08_19550	COG1595	DNA-templated transcription, initiation
BSR08_19555	COG5662	AntiSigma factor
BSR08_19560	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BSR08_19565	COG4856	YbbR-like protein
BSR08_19570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSR08_19580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSR08_19590	COG2169	Transcriptional regulator
BSR08_19595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSR08_19600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSR08_19605	COG3002	Belongs to the UPF0753 family
BSR08_19610	COG0288	reversible hydration of carbon dioxide
BSR08_19620	COG5609	conserved protein (DUF2294)
BSR08_19630	COG0642	Histidine kinase
BSR08_19640	COG0515	serine threonine protein kinase
BSR08_19655	COG1113	amino acid transport
BSR08_19670	COG2602	Beta-lactamase
BSR08_19675	COG2124	cytochrome p450
BSR08_19685	COG0531	amino acid
BSR08_19690	COG0584	glycerophosphoryl diester phosphodiesterase
BSR08_19695	COG2271	Major facilitator Superfamily
BSR08_19710	COG0456	acetyltransferase
BSR08_19710	COG1846	Transcriptional regulator
BSR08_19730	COG3409	Peptidoglycan-binding domain 1 protein
BSR08_19735	COG0697	spore germination
BSR08_19740	COG1917	Cupin 2, conserved barrel domain protein
BSR08_19740	COG2207	Transcriptional regulator
BSR08_19780	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BSR08_19785	COG3591	Belongs to the peptidase S1B family
BSR08_19795	COG0596	Alpha beta hydrolase
BSR08_19800	COG1183	phosphatidylcholine synthase activity
BSR08_19805	COG0586	Pfam SNARE associated Golgi protein
BSR08_19810	COG0688	phosphatidylethanolamine metabolic process
BSR08_19820	COG2312	Erythromycin esterase
BSR08_19825	COG2207	Transcriptional regulator
BSR08_19835	COG1301	dicarboxylic acid transport
BSR08_19840	COG2190	(PTS) system
BSR08_19840	COG1263	PTS System
BSR08_19840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSR08_19845	COG0363	glucosamine-6-phosphate deaminase activity
BSR08_19860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSR08_19865	COG0833	amino acid
BSR08_19870	COG2040	homocysteine
BSR08_19885	COG2066	Belongs to the glutaminase family
BSR08_19890	COG4191	Histidine kinase
BSR08_19895	COG0784	Response regulator, receiver
BSR08_19905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSR08_19910	COG1012	belongs to the aldehyde dehydrogenase family
BSR08_19915	COG2271	Major facilitator Superfamily
BSR08_19920	COG4948	Mandelate Racemase Muconate Lactonizing
BSR08_19925	COG2186	Transcriptional regulator
BSR08_19930	COG2721	sulfolactate sulfo-lyase activity
BSR08_19935	COG3173	Aminoglycoside phosphotransferase
BSR08_19945	COG0697	spore germination
BSR08_19950	COG0745	RESPONSE REGULATOR receiver
BSR08_19955	COG2205	protein histidine kinase activity
BSR08_19960	COG1131	(ABC) transporter
BSR08_19980	COG3773	Cell wall hydrolase
BSR08_19985	COG2304	oxidoreductase activity
BSR08_19995	COG3540	Alkaline phosphatase
BSR08_20000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSR08_20005	COG0805	protein transport
BSR08_20010	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BSR08_20015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSR08_20020	COG0477	Major facilitator Superfamily
BSR08_20025	COG1309	transcriptional regulator
BSR08_20030	COG0252	asparaginase activity
BSR08_20035	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BSR08_20040	COG1714	RDD family
BSR08_20045	COG3012	SEC-C Motif Domain Protein
BSR08_20045	COG1405	negative regulation of cell septum assembly
BSR08_20055	COG3279	Response regulator of the LytR AlgR family
BSR08_20065	COG1668	transmembrane transport
BSR08_20070	COG0667	Aldo Keto reductase
BSR08_20080	COG1595	DNA-templated transcription, initiation
BSR08_20085	COG1595	DNA-templated transcription, initiation
BSR08_20090	COG1876	peptidase activity
BSR08_20100	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_20105	COG0366	Alpha amylase catalytic
BSR08_20110	COG0803	Belongs to the bacterial solute-binding protein 9 family
BSR08_20115	COG1121	(ABC) transporter
BSR08_20120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSR08_20130	COG2310	stress, protein
BSR08_20135	COG2310	stress, protein
BSR08_20140	COG2310	stress, protein
BSR08_20145	COG0861	Integral membrane protein TerC family
BSR08_20155	COG3853	Toxic anion resistance protein (TelA)
BSR08_20165	COG2801	Transposase and inactivated derivatives
BSR08_20170	COG0477	Major facilitator Superfamily
BSR08_20175	COG2814	Major facilitator Superfamily
BSR08_20180	COG0640	Transcriptional regulator
BSR08_20185	COG4175	Glycine betaine
BSR08_20185	COG0517	IMP dehydrogenase activity
BSR08_20190	COG4176	ABC-type proline glycine betaine transport system permease component
BSR08_20195	COG2113	Glycine betaine
BSR08_20200	COG1473	amidohydrolase
BSR08_20205	COG1288	antiporter activity
BSR08_20225	COG0039	L-malate dehydrogenase activity
BSR08_20240	COG3403	YqcI/YcgG family
BSR08_20255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BSR08_20260	COG1660	Displays ATPase and GTPase activities
BSR08_20270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BSR08_20285	COG2226	methyltransferase
BSR08_20290	COG0583	DNA-binding transcription factor activity
BSR08_20295	COG3458	cephalosporin-C deacetylase activity
BSR08_20300	COG3541	Predicted nucleotidyltransferase
BSR08_20305	COG0506	proline dehydrogenase activity
BSR08_20310	COG1012	belongs to the aldehyde dehydrogenase family
BSR08_20315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSR08_20320	COG2508	Transcriptional regulator
BSR08_20325	COG3689	TIGRFAM TIGR03943 family protein
BSR08_20330	COG0701	Predicted permease
BSR08_20335	COG2267	carboxylic ester hydrolase activity
BSR08_20340	COG0492	ferredoxin-NADP+ reductase activity
BSR08_20345	COG1587	Uroporphyrinogen-III synthase
BSR08_20345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSR08_20350	COG2146	nitrite reductase [NAD(P)H] activity
BSR08_20355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSR08_20360	COG0243	molybdopterin cofactor binding
BSR08_20365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSR08_20370	COG2223	nitrite transmembrane transporter activity
BSR08_20380	COG1376	ErfK ybiS ycfS ynhG family protein
BSR08_20395	COG0765	amino acid transport
BSR08_20400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSR08_20410	COG1714	RDD family
BSR08_20420	COG1846	Transcriptional regulator
BSR08_20435	COG2723	6-phospho-beta-galactosidase activity
BSR08_20445	COG3209	COG3209 Rhs family protein
BSR08_20455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BSR08_20460	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BSR08_20465	COG1733	regulation of RNA biosynthetic process
BSR08_20475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSR08_20480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSR08_20485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSR08_20490	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BSR08_20495	COG2814	Major facilitator Superfamily
BSR08_20505	COG0697	spore germination
BSR08_20510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSR08_20520	COG2364	Membrane
BSR08_20530	COG1126	abc transporter atp-binding protein
BSR08_20535	COG0765	amino acid transport
BSR08_20540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSR08_20545	COG0583	DNA-binding transcription factor activity
BSR08_20550	COG0163	prenyltransferase activity
BSR08_20555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BSR08_20570	COG0596	Alpha beta hydrolase
BSR08_20575	COG3104	oligopeptide transport
BSR08_20580	COG5434	Belongs to the glycosyl hydrolase 28 family
BSR08_20590	COG0697	spore germination
BSR08_20600	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BSR08_20605	COG1136	(ABC) transporter
BSR08_20610	COG0577	efflux transmembrane transporter activity
BSR08_20615	COG0745	RESPONSE REGULATOR receiver
BSR08_20620	COG3850	Histidine kinase
BSR08_20620	COG5002	protein histidine kinase activity
BSR08_20625	COG0457	Tetratricopeptide repeat
BSR08_20645	COG0527	aspartate kinase activity
BSR08_20650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSR08_20655	COG4605	iron ion homeostasis
BSR08_20660	COG4604	ABC transporter, ATP-binding protein
BSR08_20665	COG4607	ABC-type enterochelin transport system periplasmic component
BSR08_20675	COG2814	Major facilitator Superfamily
BSR08_20680	COG1309	transcriptional regulator
BSR08_20685	COG0778	Nitroreductase
BSR08_20690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BSR08_20695	COG0640	Transcriptional regulator
BSR08_20700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSR08_20705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BSR08_20710	COG1012	belongs to the aldehyde dehydrogenase family
BSR08_20715	COG4975	Glucose uptake
BSR08_20720	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_20725	COG4549	nuclear export factor GLE1
BSR08_20730	COG2372	response to copper ion
BSR08_20730	COG1276	copper resistance
BSR08_20735	COG1349	DNA-binding transcription factor activity
BSR08_20745	COG2213	PTS system mannitol-specific
BSR08_20750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSR08_20755	COG0246	Mannitol dehydrogenase
BSR08_20760	COG0473	3-isopropylmalate dehydrogenase activity
BSR08_20765	COG0681	Belongs to the peptidase S26 family
BSR08_20775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSR08_20785	COG0561	phosphatase activity
BSR08_20790	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BSR08_20795	COG1914	H( )-stimulated, divalent metal cation uptake system
BSR08_20800	COG4336	lyase activity
BSR08_20805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BSR08_20810	COG1984	allophanate hydrolase subunit 2
BSR08_20815	COG1414	Transcriptional regulator
BSR08_20820	COG2755	lipolytic protein G-D-S-L family
BSR08_20830	COG2329	Antibiotic biosynthesis monooxygenase
BSR08_20835	COG0768	penicillin binding
BSR08_20840	COG4989	oxidoreductase activity
BSR08_20845	COG3711	transcriptional antiterminator
BSR08_20850	COG0318	PFAM AMP-dependent synthetase and ligase
BSR08_20855	COG2226	methyltransferase
BSR08_20860	COG1028	Short-chain dehydrogenase reductase Sdr
BSR08_20865	COG1917	Cupin 2, conserved barrel domain protein
BSR08_20870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSR08_20875	COG3871	stress protein (general stress protein 26)
BSR08_20885	COG2814	Major facilitator Superfamily
BSR08_20890	COG1522	sequence-specific DNA binding
BSR08_20895	COG0551	DNA topoisomerase type I activity
BSR08_20895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSR08_20900	COG0494	nUDIX hydrolase
BSR08_20905	COG0028	Belongs to the TPP enzyme family
BSR08_20935	COG1914	H( )-stimulated, divalent metal cation uptake system
BSR08_20940	COG2261	transglycosylase associated protein
BSR08_20945	COG4876	unkown
BSR08_20950	COG2217	Heavy metal translocating P-type atpase
BSR08_20955	COG3729	General stress protein
BSR08_20960	COG0662	Cupin 2, conserved barrel domain protein
BSR08_20965	COG2329	Antibiotic biosynthesis monooxygenase
BSR08_20970	COG3546	catalase activity
BSR08_20975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSR08_20980	COG3290	protein histidine kinase activity
BSR08_20985	COG4565	transcriptional regulatory protein
BSR08_20990	COG1301	dicarboxylic acid transport
BSR08_20995	COG0628	permease
BSR08_21005	COG1131	(ABC) transporter
BSR08_21010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BSR08_21020	COG1960	acyl-CoA dehydrogenase activity
BSR08_21035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BSR08_21040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSR08_21045	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSR08_21050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BSR08_21060	COG0513	Belongs to the DEAD box helicase family
BSR08_21065	COG3402	PFAM membrane-flanked domain
BSR08_21070	COG3428	Bacterial PH domain
BSR08_21075	COG0705	Rhomboid family
BSR08_21080	COG0736	holo-[acyl-carrier-protein] synthase activity
BSR08_21085	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BSR08_21090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSR08_21095	COG0864	Transcriptional regulator
BSR08_21100	COG2337	Toxic component of a toxin-antitoxin (TA) module
BSR08_21105	COG1366	Belongs to the anti-sigma-factor antagonist family
BSR08_21110	COG1366	Belongs to the anti-sigma-factor antagonist family
BSR08_21115	COG2172	sigma factor antagonist activity
BSR08_21120	COG2208	phosphoserine phosphatase activity
BSR08_21125	COG1366	Belongs to the anti-sigma-factor antagonist family
BSR08_21130	COG2172	sigma factor antagonist activity
BSR08_21135	COG1191	sigma factor activity
BSR08_21140	COG2208	phosphoserine phosphatase activity
BSR08_21155	COG1673	EVE domain
BSR08_21160	COG1846	Transcriptional regulator
BSR08_21165	COG2183	response to ionizing radiation
BSR08_21175	COG3091	SprT-like family
BSR08_21215	COG0582	viral genome integration into host DNA
BSR08_21220	COG2856	Zn peptidase
BSR08_21225	COG1396	sequence-specific DNA binding
BSR08_21250	COG1674	ftsk spoiiie
BSR08_21255	COG2946	Replication initiation factor
BSR08_21295	COG0433	COG0433 Predicted ATPase
BSR08_21305	COG5644	endopeptidase inhibitor activity
BSR08_21315	COG0791	NLP P60 protein
BSR08_21315	COG0741	lytic transglycosylase activity
BSR08_21330	COG0457	Tetratricopeptide repeat
BSR08_21360	COG0583	DNA-binding transcription factor activity
BSR08_21365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSR08_21375	COG5444	nuclease activity
BSR08_21380	COG1476	TRANSCRIPTIONal
BSR08_21405	COG0693	protein deglycase activity
BSR08_21410	COG1278	Cold shock
BSR08_21415	COG1329	Transcriptional regulator
BSR08_21425	COG0697	spore germination
BSR08_21430	COG1917	Cupin 2, conserved barrel domain protein
BSR08_21430	COG2207	Transcriptional regulator
BSR08_21440	COG2207	Transcriptional regulator
BSR08_21440	COG3708	Transcriptional regulator
BSR08_21445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSR08_21460	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BSR08_21475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSR08_21480	COG1309	transcriptional regulator
BSR08_21485	COG0697	spore germination
BSR08_21490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSR08_21495	COG2030	dehydratase
BSR08_21500	COG3545	Serine hydrolase
BSR08_21510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSR08_21515	COG0640	Transcriptional regulator
BSR08_21520	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BSR08_21530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSR08_21535	COG0697	spore germination
BSR08_21540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSR08_21545	COG0076	glutamate decarboxylase activity
BSR08_21550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSR08_21555	COG0640	Transcriptional regulator
BSR08_21560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSR08_21570	COG4585	Histidine kinase
BSR08_21575	COG2197	response regulator
BSR08_21580	COG2409	Drug exporters of the RND superfamily
BSR08_21585	COG0596	Alpha beta hydrolase
BSR08_21590	COG1811	Na channel or pump
BSR08_21595	COG0789	Transcriptional regulator
BSR08_21595	COG4978	Transcriptional regulator
BSR08_21600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BSR08_21605	COG0778	Nitroreductase
BSR08_21610	COG0346	lactoylglutathione lyase activity
BSR08_21615	COG2259	Doxx family
BSR08_21620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSR08_21650	COG2323	membrane
BSR08_21655	COG0071	Belongs to the small heat shock protein (HSP20) family
BSR08_21670	COG1309	transcriptional regulator
BSR08_21680	COG0456	acetyltransferase
BSR08_21690	COG1113	amino acid transport
BSR08_21695	COG2318	DinB family
BSR08_21700	COG1846	Transcriptional regulator
BSR08_21705	COG1033	growth of symbiont in host cell
BSR08_21705	COG2409	Drug exporters of the RND superfamily
BSR08_21710	COG0778	Nitroreductase
BSR08_21715	COG1846	Transcriptional regulator
BSR08_21720	COG2814	Major facilitator Superfamily
BSR08_21725	COG0730	response to heat
BSR08_21730	COG1802	Transcriptional regulator
BSR08_21735	COG3858	chitin binding
BSR08_21735	COG1388	LysM domain
BSR08_21740	COG1819	glycosyl
BSR08_21750	COG1785	Belongs to the alkaline phosphatase family
BSR08_21755	COG5646	InterPro IPR014922
BSR08_21765	COG0454	-acetyltransferase
BSR08_21770	COG1078	dGTPase activity
BSR08_21775	COG1388	LysM domain
BSR08_21780	COG2814	Major facilitator Superfamily
BSR08_21785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BSR08_21800	COG2723	6-phospho-beta-galactosidase activity
BSR08_21805	COG2188	Transcriptional regulator
BSR08_21810	COG1940	carbohydrate kinase activity
BSR08_21820	COG4124	Belongs to the glycosyl hydrolase 26 family
BSR08_21865	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BSR08_21870	COG0802	atpase or kinase
BSR08_21875	COG1214	PFAM Peptidase M22, glycoprotease
BSR08_21880	COG0456	acetyltransferase
BSR08_21885	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSR08_21890	COG0488	(ABC) transporter
BSR08_21895	COG0315	cyclic pyranopterin monophosphate synthase activity
BSR08_21900	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BSR08_21905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSR08_21910	COG0805	protein transport
BSR08_21925	COG1266	CAAX protease self-immunity
BSR08_21930	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSR08_21935	COG0459	protein refolding
BSR08_21950	COG0457	Tetratricopeptide repeat
BSR08_21955	COG1063	alcohol dehydrogenase
BSR08_21960	COG2211	Major facilitator Superfamily
BSR08_21965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSR08_21975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BSR08_21980	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BSR08_21985	COG4260	virion core protein, lumpy skin disease virus
BSR08_21995	COG2814	Major facilitator Superfamily
BSR08_22000	COG1063	alcohol dehydrogenase
BSR08_22005	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BSR08_22010	COG0823	Involved in the tonB-independent uptake of proteins
BSR08_22015	COG2801	Transposase and inactivated derivatives
BSR08_22035	COG2267	carboxylic ester hydrolase activity
BSR08_22045	COG2132	Multicopper oxidase
BSR08_22050	COG1113	amino acid transport
BSR08_22060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BSR08_22065	COG0714	Associated with various cellular activities
BSR08_22070	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BSR08_22075	COG1305	Transglutaminase-like
BSR08_22080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSR08_22080	COG0519	Catalyzes the synthesis of GMP from XMP
BSR08_22090	COG2252	PERMEase
BSR08_22095	COG3064	Membrane
BSR08_22105	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BSR08_22115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BSR08_22120	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSR08_22125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSR08_22130	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSR08_22135	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSR08_22140	COG0047	phosphoribosylformylglycinamidine synthase activity
BSR08_22145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSR08_22150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BSR08_22155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BSR08_22160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSR08_22165	COG0138	bifunctional purine biosynthesis protein purh
BSR08_22170	COG0151	Belongs to the GarS family
BSR08_22175	COG1522	sequence-specific DNA binding
BSR08_22180	COG0531	amino acid
BSR08_22190	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BSR08_22195	COG1470	cell adhesion involved in biofilm formation
BSR08_22200	COG4496	protein, YerC YecD
BSR08_22205	COG0069	glutamate synthase activity
BSR08_22215	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BSR08_22220	COG0210	DNA helicase
BSR08_22225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSR08_22230	COG4851	CamS sex pheromone cAM373 precursor
BSR08_22240	COG2801	Transposase and inactivated derivatives
BSR08_22245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSR08_22250	COG1285	pathogenesis
BSR08_22255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSR08_22260	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSR08_22265	COG0154	amidase activity
BSR08_22270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSR08_22275	COG1309	transcriptional regulator
BSR08_22280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSR08_22285	COG1597	lipid kinase activity
BSR08_22290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSR08_22320	COG5444	nuclease activity
BSR08_22330	COG0457	Tetratricopeptide repeat
BSR08_22340	COG0217	transcriptional regulatory protein
BSR08_22350	COG1309	transcriptional regulator
BSR08_22365	COG3546	catalase activity
BSR08_22370	COG0454	-acetyltransferase
BSR08_22380	COG5578	integral membrane protein
BSR08_22385	COG2972	Histidine kinase
BSR08_22395	COG1653	transport
BSR08_22400	COG1175	transmembrane transport
BSR08_22415	COG2207	Transcriptional regulator
BSR08_22525	COG1525	nuclease
BSR08_22540	COG1793	dna ligase
BSR08_22570	COG0582	viral genome integration into host DNA
BSR08_22585	COG0629	single-stranded DNA binding
BSR08_22640	COG3883	PFAM NLP P60 protein
BSR08_22640	COG0791	NLP P60 protein
BSR08_22775	COG0457	Tetratricopeptide repeat
BSR08_22820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII