locus-tag	class	description
GII80_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GII80_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GII80_00015	ENOG410848D	S4 domain protein YaaA
GII80_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GII80_00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GII80_00070	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GII80_00080	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
GII80_00085	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
GII80_00090	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GII80_00100	ENOG4105ZMH	deoxynucleoside kinase
GII80_00110	ENOG4105VRS	hydrolase family 18
GII80_00115	ENOG4105GTG	Isochorismatase
GII80_00120	ENOG4108Z6B	deaminase
GII80_00130	ENOG4105C6E	dna polymerase iii
GII80_00135	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GII80_00140	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GII80_00150	ENOG41067KS	pro-sigma K processing
GII80_00190	ENOG4105CDW	Resistance protein
GII80_00195	ENOG4105CXN	decarboxylase
GII80_00200	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GII80_00205	ENOG4105X0R	protein from nitrogen regulatory protein P-II
GII80_00210	ENOG4105XVJ	Protein of unknown function (DUF327)
GII80_00215	ENOG4105FA2	dna polymerase iii
GII80_00220	ENOG4105MA4	psp1 domain protein
GII80_00225	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
GII80_00230	ENOG41060K3	Methyltransferase
GII80_00235	ENOG4105VC4	domain protein
GII80_00240	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GII80_00245	ENOG4105KRN	Transcriptional regulator, abrb family
GII80_00250	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GII80_00255	ENOG4105F8V	Hydrolase, tatD family
GII80_00260	ENOG41069ER	domain protein
GII80_00270	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GII80_00275	ENOG4105XFA	sporulation peptidase YabG
GII80_00280	ENOG4105W42	Veg protein
GII80_00285	ENOG4105XEW	small acid-soluble spore protein
GII80_00290	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GII80_00295	ENOG4105DFT	pur operon repressor
GII80_00300	ENOG4105KME	endoribonuclease L-psp
GII80_00305	ENOG4105K4W	Could be involved in septation (By similarity)
GII80_00310	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GII80_00315	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GII80_00320	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GII80_00325	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GII80_00335	ENOG4108JA2	transcriptioN-repair coupling factor
GII80_00340	ENOG4108M14	stage v sporulation protein t
GII80_00350	ENOG4108IY2	MazG family
GII80_00355	ENOG41082I2	s4 domain protein
GII80_00360	ENOG4105VYY	sporulation protein yabp
GII80_00375	ENOG41060GV	RNA binding s1 domain protein
GII80_00405	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GII80_00410	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GII80_00415	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GII80_00425	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GII80_00430	ENOG4107U48	ppic-type peptidyL-prolyl cis-trans isomerase
GII80_00435	ENOG4105C6T	cysteine synthase
GII80_00440	ENOG4105CRQ	synthase (Component I)
GII80_00445	ENOG4105DDQ	anthranilate synthase
GII80_00450	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
GII80_00455	ENOG4105EEI	dihydropteroate synthase
GII80_00460	ENOG4105KRF	dihydroneopterin aldolase
GII80_00465	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII80_00475	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GII80_00480	ENOG4105CRK	lysyL-tRNA synthetase
GII80_00565	ENOG4108Z0C	Uvrb UvrC protein
GII80_00570	ENOG41066A3	ATP guanido phosphotransferase
GII80_00580	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GII80_00585	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
GII80_00590	ENOG4105CTP	PilT protein domain protein
GII80_00595	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GII80_00600	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GII80_00605	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GII80_00610	ENOG4105D7W	serine acetyltransferase
GII80_00615	ENOG4105C8N	cysteinyl-tRNA synthetase
GII80_00620	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII80_00625	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GII80_00630	ENOG4105M0M	Tetracycline resistance protein
GII80_00650	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GII80_00655	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GII80_00665	ENOG4108VZM	50s ribosomal protein L10
GII80_00670	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GII80_00675	ENOG4107Y49	methyltransferase
GII80_00680	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GII80_00685	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GII80_00690	ENOG4105XPM	ribosomal protein
GII80_00695	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GII80_00700	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GII80_00705	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GII80_00710	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GII80_00715	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
GII80_00720	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GII80_00725	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GII80_00730	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GII80_00735	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GII80_00740	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII80_00745	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GII80_00750	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GII80_00755	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GII80_00760	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GII80_00765	ENOG41082SA	50s ribosomal protein l29
GII80_00770	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GII80_00775	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GII80_00785	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII80_00795	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GII80_00800	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GII80_00805	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GII80_00810	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GII80_00815	ENOG4105VPB	50S ribosomal protein L30
GII80_00820	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GII80_00825	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GII80_00835	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GII80_00845	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GII80_00855	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII80_00860	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GII80_00865	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GII80_00870	ENOG4108ZT0	50S ribosomal protein l17
GII80_00875	ENOG4108JJB	ABC transporter
GII80_00880	ENOG4108JJB	ABC transporter
GII80_00885	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
GII80_00890	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GII80_00895	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GII80_00900	ENOG4108UJD	30S ribosomal protein S9
GII80_00905	ENOG4108I0C	methyltransferase
GII80_00920	ENOG4105D1F	ATP-binding protein
GII80_00935	ENOG4108NMV	polysaccharide deacetylase
GII80_01020	ENOG4105CHH	sulfate transporter
GII80_01030	ENOG4108SA1	esterase
GII80_01050	ENOG410874W	AraC family transcriptional regulator
GII80_01055	ENOG4105EHZ	conserved protein UCP016719
GII80_01060	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GII80_01080	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII80_01090	ENOG4105EWC	Purine nucleoside phosphorylase
GII80_01120	ENOG4105EMN	RNA polymerase sigma factor
GII80_01130	ENOG4105C8B	TIGR00159 family
GII80_01135	ENOG4107U5W	ybbr family
GII80_01140	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GII80_01145	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GII80_01155	ENOG4105D03	DNA-3-methyladenine glycosylase II
GII80_01165	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GII80_01170	ENOG4108TWJ	NADH dehydrogenase subunit 5
GII80_01190	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
GII80_01195	ENOG4105WAB	arsR family transcriptional regulator
GII80_01200	ENOG4108RWP	Major Facilitator Superfamily protein
GII80_01215	ENOG4107ZBH	radical SAM domain protein
GII80_01220	ENOG41066N6	Abortive infection protein
GII80_01225	ENOG4108WUZ	(ABC) transporter
GII80_01265	ENOG4105G0J	serine threonine protein kinase
GII80_01275	ENOG4106K80	
GII80_01285	ENOG4106DDH	Sporulation-specific SASP protein
GII80_01295	ENOG4108HWY	Beta-lactamase
GII80_01300	ENOG4107E6A	Cytochrome p-450
GII80_01310	ENOG4107QTZ	amino acid
GII80_01315	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
GII80_01320	ENOG4105CXY	transporter
GII80_01330	ENOG410645S	MarR family Transcriptional regulator
GII80_01335	ENOG4105DCM	major facilitator superfamily
GII80_01355	ENOG410631K	Membrane
GII80_01360	ENOG4106AXJ	AraC family transcriptional regulator
GII80_01365	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GII80_01370	ENOG4108TCS	Glutamyl endopeptidase
GII80_01380	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
GII80_01385	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
GII80_01390	ENOG4107ZTW	SNARE associated Golgi
GII80_01415	ENOG4105C72	UPF0176 protein
GII80_01425	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
GII80_01430	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GII80_01435	ENOG4108X79	transcriptional regulator
GII80_01445	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GII80_01450	ENOG4108IQI	permease
GII80_01455	ENOG4108J5H	Homocysteine s-methyltransferase
GII80_01470	ENOG4105CSV	Glutaminase
GII80_01485	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
GII80_01490	ENOG4105C26	Dehydrogenase
GII80_01495	ENOG4105DJB	Major Facilitator Superfamily
GII80_01500	ENOG4105EQX	glucarate dehydratase
GII80_01505	ENOG41073TP	transcriptional regulator
GII80_01510	ENOG4105CTX	dehydratase
GII80_01525	ENOG4106UX7	integral membrane protein
GII80_01530	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GII80_01565	ENOG4105MUA	Resistance protein
GII80_01575	ENOG4105DGI	Alkaline phosphatase
GII80_01580	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GII80_01585	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GII80_01590	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
GII80_01595	ENOG4107EPV	Aminotransferase class V
GII80_01600	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GII80_01605	ENOG4105J7D	transcriptional regulator
GII80_01610	ENOG4107RB3	L-asparaginase
GII80_01615	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
GII80_01625	ENOG41060AI	SEC-C motif
GII80_01635	ENOG4107Y7X	LytTR
GII80_01640	ENOG4108IUW	ABC transporter
GII80_01645	ENOG4108SDH	ABC, transporter
GII80_01650	ENOG4107SET	aldo keto reductase
GII80_01685	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GII80_01695	ENOG4105DSE	periplasmic solute binding protein
GII80_01700	ENOG4105DIK	(ABC) transporter
GII80_01710	ENOG4105DEN	Luciferase family
GII80_01715	ENOG4108N0M	stress protein
GII80_01720	ENOG4106FN3	tellurium resistance protein
GII80_01725	ENOG4106FN3	tellurium resistance protein
GII80_01730	ENOG4107TS3	membrane protein, TerC
GII80_01735	ENOG4108TTB	tellurium resistance protein
GII80_01745	ENOG41079KZ	Major Facilitator Superfamily
GII80_01750	ENOG4107XZQ	multidrug resistance protein
GII80_01755	ENOG4108A65	Transcriptional regulator
GII80_01760	ENOG4108IJ7	Glycine betaine
GII80_01765	ENOG4107SQ8	Glycine betaine
GII80_01795	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GII80_01830	ENOG4105EIG	urea carboxylase-associated protein 1
GII80_01835	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
GII80_01840	ENOG4105I1F	Resistance protein
GII80_01845	ENOG4107Z3Y	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GII80_01850	ENOG41089UC	methyltransferase, type 11
GII80_01855	ENOG4105C5Q	Transcriptional regulator
GII80_01860	ENOG4105I82	acetyl xylan esterase
GII80_01865	ENOG410756H	nucleotidyltransferase
GII80_01875	ENOG4105C26	Dehydrogenase
GII80_01880	ENOG4105CK7	Sodium proline symporter
GII80_01885	ENOG4107YHD	transcriptional regulator
GII80_01895	ENOG4108PJD	permease
GII80_01900	ENOG4105U6C	Alpha beta hydrolase fold protein
GII80_01910	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GII80_01915	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
GII80_01920	ENOG4108IFG	nitrite reductase, (NAD(P)H)
GII80_01925	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GII80_01945	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
GII80_01955	ENOG4105CKI	cobalamin synthesis protein
GII80_01960	ENOG4105E5Q	amino acid AbC transporter
GII80_01965	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
GII80_01975	ENOG4105HHM	rdd domain containing protein
GII80_01985	ENOG4105CS2	ec 3.2.1.21
GII80_02000	ENOG4105C8Q	Methyl-accepting chemotaxis
GII80_02005	ENOG41080HJ	6-phospho 3-hexuloisomerase
GII80_02010	ENOG4108VA3	3-hexulose-6-phosphate synthase
GII80_02015	ENOG4105KVH	Transcriptional regulator
GII80_02020	ENOG4105CEY	Amp-dependent synthetase and ligase
GII80_02050	ENOG4105SX7	Transporter
GII80_02060	ENOG4105W8Z	4'-phosphopantetheinyl transferase
GII80_02070	ENOG4105CDA	abc transporter atp-binding protein
GII80_02075	ENOG4105DRP	amino acid AbC transporter
GII80_02085	ENOG4106P55	Transcriptional regulator
GII80_02090	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GII80_02095	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GII80_02100	ENOG41069ZX	
GII80_02105	ENOG41069ZX	
GII80_02115	ENOG4105DUX	Transporter
GII80_02130	ENOG4105E1K	spore germination protein
GII80_02150	ENOG4107WD8	ABC transporter, permease
GII80_02155	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GII80_02160	ENOG4105BZU	Histidine kinase
GII80_02185	ENOG4105CFH	Aspartokinase
GII80_02190	ENOG4105DHS	permease protein
GII80_02195	ENOG4105CM4	permease protein
GII80_02200	ENOG4108IPW	abc transporter atp-binding protein
GII80_02215	ENOG4105R8C	Transcriptional regulator
GII80_02220	ENOG4108DBC	nitroreductase
GII80_02225	ENOG41067V3	Antibiotic biosynthesis monooxygenase
GII80_02230	ENOG4105YVS	arsR family transcriptional regulator
GII80_02240	ENOG4108JPW	Aminotransferase
GII80_02245	ENOG4105C26	Dehydrogenase
GII80_02255	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GII80_02260	ENOG4105KTB	nuclear export factor GLE1
GII80_02265	ENOG4108T5E	Copper resistance protein
GII80_02270	ENOG4108ZYE	Transcriptional regulator
GII80_02295	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GII80_02300	ENOG4108ZX0	Signal peptidase I
GII80_02325	ENOG4105E7W	lamb ycsf family protein
GII80_02330	ENOG4105C5A	transporter
GII80_02335	ENOG4105CFM	UPF0317 protein
GII80_02340	ENOG4105P4J	Allophanate hydrolase, subunit 1
GII80_02350	ENOG4107258	Transcriptional regulator
GII80_02355	ENOG4105XJB	lipolytic protein G-D-S-L family
GII80_02365	ENOG41061CK	Antibiotic biosynthesis monooxygenase
GII80_02370	ENOG4107RVG	penicillin-binding protein
GII80_02375	ENOG4107QM2	Aldo Keto reductase
GII80_02380	ENOG4105ETD	TRANSCRIPTIONal
GII80_02390	ENOG4105HMZ	Methyltransferase
GII80_02395	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GII80_02410	ENOG410606W	general stress protein
GII80_02420	ENOG4105VCH	membrane
GII80_02430	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GII80_02445	ENOG4105I5R	Uncharacterized protein conserved in bacteria (DUF2334)
GII80_02450	ENOG4107R8N	Glycosyl transferase, family 2
GII80_02460	ENOG4105C0X	amino acid
GII80_02485	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GII80_02495	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
GII80_02500	ENOG4105EU9	
GII80_02505	ENOG4105QVS	general stress protein
GII80_02510	ENOG41082W1	Cupin 2, conserved barrel domain protein
GII80_02525	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GII80_02530	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GII80_02535	ENOG4108MRH	transcriptional regulatory protein
GII80_02540	ENOG4107QJT	sodium dicarboxylate symporter
GII80_02545	ENOG4106F5Q	Membrane
GII80_02550	ENOG4105CJ1	ABC, transporter
GII80_02565	ENOG4105FDT	acyl-CoA dehydrogenase
GII80_02585	ENOG4105SZ6	Thioredoxin
GII80_02590	ENOG4105CPF	Cell wall formation (By similarity)
GII80_02595	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
GII80_02600	ENOG4105C1J	atp-dependent rna helicase
GII80_02605	ENOG410905X	membrane-flanked domain protein
GII80_02610	ENOG4105CKV	Membrane
GII80_02620	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GII80_02625	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
GII80_02630	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GII80_02640	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
GII80_02645	ENOG4107MMM	Anti-sigma-factor antagonist
GII80_02650	ENOG4105FUA	antagonist
GII80_02655	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
GII80_02660	ENOG4107SGM	protein serine threonine phosphatase
GII80_02665	ENOG4105WN5	stage II sporulation protein
GII80_02670	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
GII80_02680	ENOG41064BQ	Phosphatase
GII80_02695	ENOG4105M5P	UPF0310 protein
GII80_02700	ENOG4105RV9	Transcriptional regulator
GII80_02755	ENOG4105DEN	Luciferase family
GII80_02770	ENOG4108W2Y	isochorismatase
GII80_02775	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
GII80_02780	ENOG4108HH4	Major Facilitator Superfamily
GII80_02800	ENOG4108V4B	ThiJ pfpI
GII80_02805	ENOG4105VEQ	Cold shock protein
GII80_02810	ENOG4108VJ1	Transcriptional regulator (CarD family
GII80_02820	ENOG4108MCI	Transcriptional regulator, ARAC family
GII80_02825	ENOG4108UZ3	Transporter
GII80_02830	ENOG41086D8	Transcriptional regulator
GII80_02835	ENOG4107U9B	transcriptional regulator
GII80_02840	ENOG4105DXI	Major Facilitator superfamily
GII80_02850	ENOG4105CZ9	Domain of unknown function (DU1801)
GII80_02855	ENOG4105GIG	
GII80_02860	ENOG4105T38	integral membrane protein
GII80_02865	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GII80_02870	ENOG4108ZMQ	domain protein
GII80_02875	ENOG4105MJ9	esterase
GII80_02880	ENOG4107Z6X	Transcriptional regulator
GII80_02890	ENOG4105KVH	Transcriptional regulator
GII80_02895	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GII80_02900	ENOG4105EQ0	Major Facilitator superfamily
GII80_02905	ENOG4108JGH	Tetr family transcriptional regulator
GII80_02915	ENOG41082YX	Transcriptional regulator, arsr family
GII80_02920	ENOG4107R5R	arsenical pump membrane protein
GII80_02930	ENOG4105Z7P	Acetyltransferase (GNAT) family
GII80_02935	ENOG4107Y9U	Membrane
GII80_02945	ENOG4108SQ9	flavin reductase domain protein, FMN-binding
GII80_02950	ENOG4108ZHR	arsR family transcriptional regulator
GII80_02955	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GII80_02970	ENOG4105ENE	Histidine kinase
GII80_02975	ENOG4108VB1	regulatoR
GII80_02980	ENOG4105EYF	MMPL domain protein
GII80_02985	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
GII80_02990	ENOG4108UQV	Membrane
GII80_02995	ENOG4108Z5V	transcriptional regulator, merr family
GII80_03000	ENOG41076HS	cation diffusion facilitator family transporter
GII80_03005	ENOG4108TVJ	Nitroreductase
GII80_03010	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
GII80_03015	ENOG4108VGI	doxx family
GII80_03020	ENOG4105XXY	Thioredoxin
GII80_03035	ENOG410900G	Protein of unknown function (DUF421)
GII80_03040	ENOG4108QY0	Membrane
GII80_03060	ENOG4105PF9	Transcriptional regulator
GII80_03070	ENOG4105WQG	acetyltransferase
GII80_03080	ENOG4105C85	amino acid
GII80_03090	ENOG41062A4	Transcriptional regulator
GII80_03095	ENOG4105EYF	MMPL domain protein
GII80_03100	ENOG4108TVJ	Nitroreductase
GII80_03105	ENOG4105FS7	Transcriptional regulator
GII80_03110	ENOG4105C2C	drug resistance transporter, Bcr CflA
GII80_03120	ENOG4105DRR	Transcriptional regulator, GntR family
GII80_03125	ENOG4105VRS	hydrolase family 18
GII80_03140	ENOG4105G6Z	alkaline phosphatase
GII80_03145	ENOG4108ZMX	Domain of unknown function (DU1801)
GII80_03155	ENOG4108YM7	Gcn5-related n-acetyltransferase
GII80_03160	ENOG4107TVP	HD domain protein
GII80_03165	ENOG41090UD	(LipO)protein
GII80_03170	ENOG4105F27	Major Facilitator
GII80_03175	ENOG4105VZJ	PTS System
GII80_03180	ENOG4105VCP	PTS System
GII80_03185	ENOG4105CK1	PTS System
GII80_03190	ENOG4105CS2	ec 3.2.1.21
GII80_03195	ENOG4108TZY	GntR Family Transcriptional Regulator
GII80_03200	ENOG4105EVU	fructokinase
GII80_03205	ENOG4105DG6	mannose-6-phosphate isomerase
GII80_03210	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
GII80_03255	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GII80_03260	ENOG4105K8N	protein family UPF0079, ATPase
GII80_03265	ENOG41072GX	Peptidase M22 Glycoprotease
GII80_03270	ENOG410801F	ribosomal-protein-alanine acetyltransferase
GII80_03275	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GII80_03280	ENOG4105C5H	ABC transporter
GII80_03285	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GII80_03290	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
GII80_03295	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GII80_03300	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GII80_03310	ENOG4108TYN	CAAX amino terminal protease family protein
GII80_03315	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GII80_03320	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GII80_03345	ENOG4105DVF	Cytosine-specific methyltransferase
GII80_03350	ENOG4107RHI	Cytosine-specific methyltransferase
GII80_03390	ENOG4105PGZ	NB-ARC domain
GII80_03395	ENOG4105CPQ	Dehydrogenase
GII80_03400	ENOG4105CT4	transporter
GII80_03410	ENOG41087YS	Phage shock protein A
GII80_03415	ENOG4105DQX	Zinc finger domain
GII80_03420	ENOG4108WV1	Pfam:DUF477
GII80_03430	ENOG4108ZMR	Ion transport 2 domain-containing protein
GII80_03435	ENOG4107QNK	)-transporter
GII80_03465	ENOG4107YUH	hydrolase
GII80_03475	ENOG4107STQ	Multicopper oxidase
GII80_03480	ENOG4105C85	amino acid
GII80_03495	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GII80_03515	ENOG4105C7N	Xanthine uracil vitamin C permease
GII80_03540	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GII80_03545	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GII80_03550	ENOG4105C83	adenylosuccinate lyase
GII80_03555	ENOG4105C8V	SAICAR synthetase
GII80_03560	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
GII80_03565	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
GII80_03570	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
GII80_03580	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GII80_03585	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GII80_03590	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GII80_03595	ENOG4105C12	Phosphoribosylglycinamide synthetase
GII80_03605	ENOG4105DVH	amino acid
GII80_03620	ENOG4108R5T	secreted protein
GII80_03625	ENOG4105KGF	protein, YerC YecD
GII80_03630	ENOG4105CBC	glutamate synthase
GII80_03635	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
GII80_03640	ENOG4105C4R	Atp-dependent dna helicase
GII80_03645	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GII80_03655	ENOG4105CRN	Aminoglycoside phosphotransferase
GII80_03660	ENOG4105KT7	mgtC SapB transporter
GII80_03665	ENOG4105CK7	Sodium proline symporter
GII80_03670	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GII80_03675	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GII80_03680	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GII80_03685	ENOG4108IG5	Transcriptional regulator
GII80_03695	ENOG4105CBD	Diacylglycerol kinase
GII80_03700	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GII80_03715	ENOG4105D85	methylase
GII80_03720	ENOG4105F6A	helicase
GII80_03725	ENOG4105ECI	YeeC-like protein
GII80_03765	ENOG4105CDY	transcriptional regulatory protein
GII80_03775	ENOG4105M4P	Tetr family transcriptional regulator
GII80_03780	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
GII80_03785	ENOG4107S9F	NmrA family
GII80_03800	ENOG4105WEF	catalase
GII80_03805	ENOG4105M18	-acetyltransferase
GII80_03820	ENOG4105C2F	Histidine kinase
GII80_03825	ENOG4105EQD	regulatoR
GII80_03830	ENOG410769Z	extracellular solute-binding protein family 1
GII80_03835	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GII80_03840	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GII80_03845	ENOG4105F5H	Glycosyl Hydrolase Family 88
GII80_03850	ENOG41075H3	AraC family transcriptional regulator
GII80_03855	ENOG4107TDE	lipolytic protein G-D-S-L family
GII80_03870	ENOG4105CX8	fg-gap repeat protein
GII80_03875	ENOG4105CX8	fg-gap repeat protein
GII80_03880	ENOG4107TDE	lipolytic protein G-D-S-L family
GII80_03890	ENOG4105EKC	
GII80_03895	ENOG4105E0S	extracellular solute-binding protein family 1
GII80_03905	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GII80_03910	ENOG4105F8D	glycoside hydrolase family 4
GII80_03915	ENOG4105H67	Protein of unknown function (DUF421)
GII80_03920	ENOG4105Z26	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
GII80_03925	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GII80_03945	ENOG4106I4J	membrane
GII80_03950	ENOG4108PCN	EamA-like transporter family
GII80_03955	ENOG41082F9	transcriptional regulator
GII80_03960	ENOG41061H0	Monooxygenase
GII80_03965	ENOG4108R1P	
GII80_03970	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GII80_03975	ENOG4105E0M	Sulfatase
GII80_03980	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
GII80_03990	ENOG41090R9	glycosyltransferase
GII80_03995	ENOG4107R51	Glycosyl transferase, family 2
GII80_04000	ENOG41090R9	glycosyltransferase
GII80_04005	ENOG4105EU0	Major facilitator Superfamily
GII80_04015	ENOG4105CUB	amino acid
GII80_04020	ENOG4105C26	Dehydrogenase
GII80_04025	ENOG4105FKZ	Methyl-accepting chemotaxis
GII80_04030	ENOG4105C5H	ABC transporter
GII80_04040	ENOG4107SWG	transcriptional regulator MERR family
GII80_04045	ENOG4105DXB	Major Facilitator superfamily
GII80_04055	ENOG4105C5H	ABC transporter
GII80_04060	ENOG4105FDU	atp-dependent rna helicase
GII80_04070	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
GII80_04080	ENOG4105E6M	Sulphatase-modifying factor protein
GII80_04085	ENOG4105E0A	ABC, transporter
GII80_04090	ENOG4108U1V	ABC transporter, permease
GII80_04095	ENOG4105DQ5	transport system permease protein
GII80_04100	ENOG4108HUF	Transporter
GII80_04115	ENOG4108J20	pectate lyase
GII80_04120	ENOG4107QPK	)-transporter
GII80_04130	ENOG4108MRH	transcriptional regulatory protein
GII80_04155	ENOG410855V	Acylphosphatase
GII80_04160	ENOG4108RPX	mosc domain containing protein
GII80_04180	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
GII80_04210	ENOG4105GEU	Spore germination protein
GII80_04220	ENOG4108Q5U	germination protein, ger(x)c family
GII80_04225	ENOG4105E1K	spore germination protein
GII80_04230	ENOG4105C5Y	PTS System
GII80_04235	ENOG4105CG3	alpha amylase, catalytic region
GII80_04240	ENOG4107414	GntR family transcriptional regulator
GII80_04245	ENOG4108RCM	Nitroreductase
GII80_04250	ENOG4105CGH	5'-nucleotidase
GII80_04255	ENOG4107RKG	DJ-1/PfpI family
GII80_04270	ENOG4105KJF	protein tyrosine phosphatase
GII80_04280	ENOG4107U9T	Pfam:Ribonuclease_BN
GII80_04285	ENOG4108ISG	Major Facilitator
GII80_04295	ENOG4105UPD	Calcium Proton
GII80_04305	ENOG4105D8X	mechanosensitive ion channel
GII80_04325	ENOG4106KE4	Dehydrogenase
GII80_04330	ENOG4105D7N	magnesium and cobalt transport protein CorA
GII80_04340	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GII80_04365	ENOG4107RUY	(E1 component), alpha subunit
GII80_04375	ENOG4107QKR	Dehydrogenase
GII80_04385	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GII80_04390	ENOG41069DP	small acid-soluble spore protein
GII80_04395	ENOG4105KK4	UPF0060 membrane protein
GII80_04425	ENOG4105F8D	glycoside hydrolase family 4
GII80_04430	ENOG4108Q3X	Transcriptional regulator
GII80_04435	ENOG4105CI1	PTS System
GII80_04440	ENOG4105BZ1	(ABC) transporter
GII80_04445	ENOG4105BZ1	(ABC) transporter
GII80_04455	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
GII80_04460	ENOG4105ID8	Transcriptional regulator, ARAC family
GII80_04465	ENOG4107QNK	)-transporter
GII80_04470	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
GII80_04475	ENOG4105CIB	oxidoreductase Domain protein
GII80_04480	ENOG4105BZU	Histidine kinase
GII80_04485	ENOG4105WH1	Two component transcriptional regulator luxr family
GII80_04490	ENOG4105CJ1	ABC, transporter
GII80_04495	ENOG41090VJ	ABC-2 type transporter
GII80_04500	ENOG4108KYE	ABC-2 type transporter
GII80_04505	ENOG4105U3E	Transcriptional regulator
GII80_04510	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
GII80_04515	ENOG4105H93	Acyltransferase family
GII80_04520	ENOG4105YA8	Transcriptional regulator
GII80_04525	ENOG4107Y80	Major Facilitator superfamily
GII80_04530	ENOG4108YYS	metal-dependent hydrolase (By similarity)
GII80_04535	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GII80_04540	ENOG410834F	Transcriptional regulator
GII80_04550	ENOG4108MES	Periplasmic binding protein
GII80_04555	ENOG4105DQ5	transport system permease protein
GII80_04560	ENOG4108IHU	transport system permease protein
GII80_04565	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GII80_04570	ENOG4107Y03	Nitroreductase
GII80_04585	ENOG4105ECP	epimerase
GII80_04600	ENOG4105F27	Major Facilitator
GII80_04620	ENOG4106AKJ	
GII80_04625	ENOG4105D74	hydrolase
GII80_04630	ENOG4105CKK	Glycosyl transferase, family 2
GII80_04635	ENOG4105EJV	Membrane
GII80_04640	ENOG41067AE	Membrane-bound metal-dependent hydrolase
GII80_04645	ENOG4105CEN	a g-specific adenine glycosylase
GII80_04650	ENOG4106BXE	
GII80_04655	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
GII80_04670	ENOG4105EVI	UPF0374 protein
GII80_04675	ENOG4105BZ1	(ABC) transporter
GII80_04680	ENOG4107NBY	Membrane
GII80_04690	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII80_04695	ENOG4105G5W	regulator Fur family
GII80_04805	ENOG4108N23	SpoOM-related protein
GII80_04820	ENOG4105EC3	peptidase S51, dipeptidase E
GII80_04825	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GII80_04830	ENOG4105DNP	FAD linked oxidase domain protein
GII80_04845	ENOG4105E2Y	ABC, transporter
GII80_04850	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
GII80_04855	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
GII80_04860	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
GII80_04870	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GII80_04875	ENOG4107D63	
GII80_04880	ENOG4105VZ8	Transcriptional regulator
GII80_04895	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GII80_04905	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GII80_04925	ENOG4105CYN	Serine protein kinase
GII80_04930	ENOG4106AKX	UPF0229 protein
GII80_04935	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
GII80_04940	ENOG4105CW7	secretion protein, HlyD family
GII80_04945	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GII80_04950	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GII80_04970	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
GII80_04975	ENOG4105CZV	ABC transporter
GII80_04980	ENOG4105CJ1	ABC, transporter
GII80_04985	ENOG4108TU7	Inherit from COG: (ABC) transporter
GII80_04990	ENOG4105VEQ	Cold shock protein
GII80_05000	ENOG4105BZU	Histidine kinase
GII80_05040	ENOG4108YBP	pseudouridine synthase
GII80_05050	ENOG41080XP	Cbs domain
GII80_05055	ENOG4107YBY	Hydrolase
GII80_05060	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
GII80_05065	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GII80_05070	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
GII80_05080	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GII80_05085	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GII80_05095	ENOG4105BZU	Histidine kinase
GII80_05100	ENOG4105WH1	Two component transcriptional regulator luxr family
GII80_05135	ENOG4105ED1	spovr family
GII80_05140	ENOG4105G6Z	alkaline phosphatase
GII80_05155	ENOG4105BZN	citrate synthase
GII80_05160	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GII80_05165	ENOG4105CUB	amino acid
GII80_05170	ENOG4105C8J	)-transporter
GII80_05175	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GII80_05190	ENOG4105J37	
GII80_05195	ENOG4108AEY	RNA polymerase sigma factor
GII80_05200	ENOG4108FN7	Aldo keto reductase
GII80_05205	ENOG4105F6E	Acyl-transferase
GII80_05210	ENOG4105C37	(CBS) domain
GII80_05220	ENOG4105CHM	Aminotransferase
GII80_05225	ENOG4105C37	(CBS) domain
GII80_05235	ENOG4105WMR	Protein CrcB homolog
GII80_05240	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GII80_05250	ENOG4105D64	Mechanosensitive ion channel
GII80_05255	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GII80_05260	ENOG4107VMI	polysaccharide deacetylase
GII80_05265	ENOG4105F0I	Aminotransferase
GII80_05285	ENOG4105BZ1	(ABC) transporter
GII80_05290	ENOG4105BZ1	(ABC) transporter
GII80_05315	ENOG410839P	
GII80_05325	ENOG4106MP8	UPF0754 membrane protein
GII80_05330	ENOG4105WZB	UPF0342 protein
GII80_05335	ENOG4105F1N	DNA alkylation repair
GII80_05345	ENOG4105D4P	Coproporphyrinogen iii oxidase
GII80_05350	ENOG4107S91	Sodium hydrogen exchanger
GII80_05355	ENOG4105NCW	Trka-c domain protein
GII80_05365	ENOG4105CGU	Enoyl-CoA hydratase
GII80_05375	ENOG4108IUX	(ABC) transporter
GII80_05380	ENOG4105RHA	ABC transporter, permease
GII80_05385	ENOG4107VRP	DNA repair exonuclease
GII80_05390	ENOG4106D4I	domain protein
GII80_05395	ENOG4105EQI	Metal Dependent Phosphohydrolase
GII80_05405	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
GII80_05450	ENOG4105NBU	tryptophan transport protein
GII80_05455	ENOG4105DXJ	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GII80_05460	ENOG4105K59	histidine triad (HIT) protein
GII80_05495	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
GII80_05500	ENOG4105BZ4	penicillin-binding protein
GII80_05505	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GII80_05510	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GII80_05515	ENOG4105C1Q	protoporphyrinogen oxidase
GII80_05525	ENOG4105ECB	domain protein
GII80_05535	ENOG41090T1	Membrane
GII80_05545	ENOG4105DER	m42 family
GII80_05560	ENOG4106AXD	
GII80_05565	ENOG4108RQ5	Beta-lactamase domain-containing protein
GII80_05570	ENOG4105DF9	Lipoate-protein, ligase
GII80_05580	ENOG4105CEY	Amp-dependent synthetase and ligase
GII80_05590	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
GII80_05595	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GII80_05600	ENOG4105KD7	acetyltransferase
GII80_05610	ENOG4108HUF	Transporter
GII80_05615	ENOG4107TB6	phosphoglycerate mutase
GII80_05625	ENOG4107F3J	Amp-dependent synthetase and ligase
GII80_05630	ENOG4107ZYJ	bioY protein
GII80_05635	ENOG4106YBV	Methyl-accepting chemotaxis
GII80_05655	ENOG4105XVF	Competence transcription factor
GII80_05660	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GII80_05665	ENOG4105X3H	Excalibur domain protein
GII80_05670	ENOG4105E1V	na solute symporter
GII80_05675	ENOG4106CAD	Protein of unknown function (DUF3311)
GII80_05680	ENOG41060YP	
GII80_05695	ENOG4107SCK	Monooxygenase
GII80_05700	ENOG4108INS	Transcriptional regulator
GII80_05715	ENOG4105TRI	Hydrolase
GII80_05730	ENOG4108KK1	membrane protein AbrB duplication
GII80_05735	ENOG4106K7D	Major facilitator family transporter
GII80_05740	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
GII80_05745	ENOG4105VWP	Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding
GII80_05760	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
GII80_05770	ENOG4105EYH	Exonuclease
GII80_05820	ENOG4105ERH	Fumarylacetoacetate hydrolase
GII80_05830	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GII80_05840	ENOG4105CAQ	asparagine synthetase
GII80_05855	ENOG4105UQX	Mate efflux family protein
GII80_05860	ENOG4106HBX	Transcriptional Regulator AraC Family
GII80_05865	ENOG4105ETE	Transcriptional regulator (LacI family
GII80_05870	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
GII80_05875	ENOG4105SF0	DinB family
GII80_05880	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GII80_05885	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GII80_05890	ENOG4105MYW	Pentapeptide repeat protein
GII80_05895	ENOG4107S9D	Alpha beta hydrolase
GII80_05900	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GII80_05905	ENOG4107RIQ	Sulfate adenylate transferase
GII80_05910	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GII80_05915	ENOG4108N5B	2-phosphosulfolactate phosphatase
GII80_05920	ENOG41061P3	phosphosulfolactate synthase
GII80_05930	ENOG4105DIA	mandelate racemase muconate lactonizing
GII80_05935	ENOG4107RCC	Major Facilitator Superfamily
GII80_05940	ENOG4108SZE	gCN5-related N-acetyltransferase
GII80_05945	ENOG4105MA6	gCN5-related N-acetyltransferase
GII80_05955	ENOG4108VPT	UPF0234 protein
GII80_05960	ENOG4105QNR	S1 RNA binding domain protein
GII80_05980	ENOG4105K7K	Transcriptional regulator
GII80_05990	ENOG410751J	
GII80_05995	ENOG4105D4Y	metalloprotease
GII80_06000	ENOG4105EPR	degv family
GII80_06005	ENOG4107AYK	membrAne
GII80_06015	ENOG41073B9	
GII80_06020	ENOG4108KP7	hydrolase
GII80_06025	ENOG4108MXZ	Esterase
GII80_06030	ENOG4105VG1	fes assembly suf system protein
GII80_06040	ENOG4105IQ5	FAD linked oxidase domain protein
GII80_06050	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GII80_06065	ENOG4105C8Y	Acetylornithine aminotransferase
GII80_06070	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GII80_06080	ENOG4105DBV	ornithine carbamoyltransferase
GII80_06105	ENOG4107RMD	Basic membrane lipoprotein
GII80_06120	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GII80_06125	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GII80_06135	ENOG4105C3U	ABC transporter
GII80_06140	ENOG4108JQ7	(ABC) transporter
GII80_06155	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GII80_06165	ENOG4105C31	Tryptophanyl-tRNA synthetase
GII80_06170	ENOG4108J59	Extracellular solute-binding protein, family 5
GII80_06175	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GII80_06180	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GII80_06190	ENOG4108JQ7	(ABC) transporter
GII80_06205	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
GII80_06210	ENOG4108ZCF	integral membrane protein
GII80_06220	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GII80_06235	ENOG4105DPN	Oligoendopeptidase f
GII80_06245	ENOG4105T58	Dithiol-disulfide isomerase
GII80_06250	ENOG4108Z18	K06886 hemoglobin
GII80_06255	ENOG4105E4C	Lytic transglycosylase catalytic
GII80_06260	ENOG4105MIX	Adenylate cyclase
GII80_06275	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GII80_06280	ENOG4105EMS	pseudouridine synthase
GII80_06295	ENOG4105ETU	transcriptional activator (TenA
GII80_06300	ENOG4108VEU	Thiamine monophosphate synthase
GII80_06315	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GII80_06320	ENOG4105D06	uba thif-type nad fad binding protein
GII80_06325	ENOG4105DWF	phosphomethylpyrimidine kinase
GII80_06330	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GII80_06335	ENOG4107A88	
GII80_06385	ENOG4105ENA	helicase
GII80_06400	ENOG4108ZMI	UPF0477 protein
GII80_06410	ENOG4105C28	cystathionine
GII80_06415	ENOG4105C28	cystathionine
GII80_06420	ENOG4105D9U	N-acetyltransferase
GII80_06425	ENOG4105JHY	Membrane
GII80_06435	ENOG41068SY	
GII80_06455	ENOG4107KNS	
GII80_06480	ENOG4108PSK	reductase
GII80_06495	ENOG4105DM4	PTS System
GII80_06500	ENOG4105DG6	mannose-6-phosphate isomerase
GII80_06505	ENOG4105G7B	Protein of unknown function (DUF2992)
GII80_06510	ENOG4105VMI	-acetyltransferase
GII80_06520	ENOG4108Z66	YbaK ebsC protein
GII80_06535	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GII80_06545	ENOG4108ZJ4	polysaccharide deacetylase
GII80_06550	ENOG4107CUJ	Protein of unknown function (DUF2690)
GII80_06575	ENOG4108IEG	Formate dehydrogenase Alpha subunit
GII80_06600	ENOG4106A3M	Cytochrome p-450
GII80_06605	ENOG41087PP	glycosyltransferase MGT family
GII80_06615	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
GII80_06620	ENOG4105C4B	ABC transporter, permease
GII80_06625	ENOG4108IXI	(ABC) transporter
GII80_06635	ENOG4105Q95	Cupin 2, conserved barrel domain protein
GII80_06650	ENOG4105D2H	Uronic isomerase
GII80_06655	ENOG4105CT4	transporter
GII80_06660	ENOG4105DG4	malate L-lactate dehydrogenase
GII80_06665	ENOG4105CPQ	Dehydrogenase
GII80_06670	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
GII80_06675	ENOG4105DMW	Dehydrogenase reductase
GII80_06680	ENOG4108I5G	Major Facilitator superfamily
GII80_06685	ENOG4107KJX	Transcriptional regulator
GII80_06690	ENOG4107QZW	Altronate oxidoreductase
GII80_06695	ENOG4105CTX	dehydratase
GII80_06700	ENOG4107TSN	permease
GII80_06710	ENOG4105JD4	ATPase yjob
GII80_06725	ENOG41068K0	YCII-related domain
GII80_06730	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
GII80_06735	ENOG4105KWG	Pfam:DUF1696
GII80_06740	ENOG4105K7W	phage-related replication protein
GII80_06745	ENOG4105WEF	catalase
GII80_06750	ENOG410635T	phage-like element pbsx protein
GII80_06795	ENOG4108TFU	terminase (Small subunit)
GII80_06800	ENOG4105IG6	Phage terminase, large subunit
GII80_06805	ENOG4108MDF	Phage Portal Protein
GII80_06830	ENOG41060SN	
GII80_06845	ENOG4105PQS	phage protein
GII80_06850	ENOG4105FR7	XkdM protein, phage-like element PBSX
GII80_06855	ENOG4105MTC	XkdN-like protein
GII80_06865	ENOG4108FKH	Transglycosylase SLT domain
GII80_06870	ENOG4108WZM	domain protein
GII80_06875	ENOG4105X7F	
GII80_06885	ENOG4105MFU	Protein of unknown function (DUF2634)
GII80_06890	ENOG41066EA	baseplate J family protein
GII80_06895	ENOG410906S	phage-like element pbsx protein xkdt
GII80_06905	ENOG41068G1	
GII80_06935	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
GII80_06955	ENOG4105CJ3	phosphate transporter
GII80_06960	ENOG4107GRR	phosphate transport regulator
GII80_06965	ENOG4107R7I	amino acid
GII80_06980	ENOG4105EDW	glycosyl transferase, family 39
GII80_06985	ENOG4105CKK	Glycosyl transferase, family 2
GII80_06990	ENOG4105C0H	protease
GII80_07000	ENOG4108ME1	Peptidase M55 D-aminopeptidase
GII80_07005	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GII80_07010	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GII80_07015	ENOG4105C3U	ABC transporter
GII80_07025	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GII80_07030	ENOG4105DTQ	mandelate racemase muconate lactonizing
GII80_07035	ENOG4107SN7	NLP P60 protein
GII80_07040	ENOG4108JQ7	(ABC) transporter
GII80_07045	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GII80_07050	ENOG4107TUM	Amidinotransferase
GII80_07055	ENOG4108S4H	thioesterase Superfamily protein
GII80_07060	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GII80_07080	ENOG4108428	Inherit from COG: -acetyltransferase
GII80_07090	ENOG41080TC	multidrug resistance protein
GII80_07095	ENOG4105CIY	formyltetrahydrofolate deformylase
GII80_07100	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GII80_07115	ENOG4105K56	Transcriptional regulator
GII80_07120	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GII80_07130	ENOG4107Y2X	deaminase
GII80_07135	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GII80_07140	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GII80_07150	ENOG4108W7F	transporter, permease
GII80_07155	ENOG4108JJB	ABC transporter
GII80_07160	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
GII80_07165	ENOG4108X43	YKOF domain protein
GII80_07170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GII80_07175	ENOG41062D9	Histidine kinase
GII80_07185	ENOG4106849	propeptide, pepSY amd peptidase M4
GII80_07195	ENOG4105CJW	magnesium transporter
GII80_07200	ENOG4105V75	Transcriptional regulator
GII80_07245	ENOG4105DQE	DNA ligase
GII80_07250	ENOG4105FDF	Could be involved in DNA repair (By similarity)
GII80_07255	ENOG4105BZU	Histidine kinase
GII80_07260	ENOG4107T5V	SNARE associated Golgi
GII80_07265	ENOG4107TS3	membrane protein, TerC
GII80_07270	ENOG4108WZW	RNA polymerase sigma
GII80_07280	ENOG410681C	small acid-soluble spore protein
GII80_07290	ENOG4105D0M	Protease HtpX homolog
GII80_07310	ENOG4108TGC	Acyltransferase
GII80_07315	ENOG4105BZU	Histidine kinase
GII80_07320	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GII80_07330	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
GII80_07335	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
GII80_07340	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
GII80_07350	ENOG4107T6J	Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit
GII80_07355	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
GII80_07360	ENOG4107V49	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
GII80_07365	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
GII80_07385	ENOG4105BZU	Histidine kinase
GII80_07390	ENOG41090MY	MarR family Transcriptional regulator
GII80_07395	ENOG4105ER2	Ompa motb domain protein
GII80_07400	ENOG4105E14	MotA TolQ exbB proton channel
GII80_07410	ENOG4108K88	Membrane
GII80_07415	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GII80_07420	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
GII80_07425	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GII80_07430	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GII80_07440	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
GII80_07445	ENOG4105FEA	Spore maturation protein
GII80_07475	ENOG4105F0V	Cell wall hydrolase
GII80_07490	ENOG4105C59	p-type ATPase
GII80_07500	ENOG4105DC7	peptidase M24
GII80_07510	ENOG4105CID	antiterminator
GII80_07520	ENOG4105KRI	phosphocarrier protein (HPr
GII80_07525	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GII80_07535	ENOG4105F6S	Spore photoproduct lyase
GII80_07545	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
GII80_07550	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GII80_07555	ENOG4105K4I	Scp-like extracellular
GII80_07565	ENOG4105BZU	Histidine kinase
GII80_07570	ENOG4105CHM	Aminotransferase
GII80_07580	ENOG4107R88	Chemotaxis protein (CheV)
GII80_07585	ENOG4105UIN	
GII80_07595	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
GII80_07605	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
GII80_07610	ENOG4105ESF	Peptidoglycan binding domain protein
GII80_07615	ENOG4105ESF	Peptidoglycan binding domain protein
GII80_07625	ENOG4105EPM	Diguanylate phosphodiesterase
GII80_07630	ENOG4107IN1	Protein of unknown function (DUF1797)
GII80_07635	ENOG4108XRC	Protein of unknown function (DUF458) 
GII80_07665	ENOG4105NQC	Flavodoxin
GII80_07675	ENOG4105CH2	amidohydrolase
GII80_07685	ENOG4105D8X	mechanosensitive ion channel
GII80_07690	ENOG4105D3R	alkyl hydroperoxide reductase
GII80_07695	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII80_07710	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GII80_07715	ENOG4105D06	uba thif-type nad fad binding protein
GII80_07720	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GII80_07725	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
GII80_07730	ENOG4108ZAF	Molybdopterin
GII80_07735	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
GII80_07740	ENOG4105BZ1	(ABC) transporter
GII80_07745	ENOG4105BZ1	(ABC) transporter
GII80_07755	ENOG4107X8C	Efflux transporter RND family MFP subunit
GII80_07760	ENOG4105C19	ABC transporter
GII80_07765	ENOG4107RBB	ABC transporter, permease
GII80_07770	ENOG4105E98	transcriptional regulator DeoR family
GII80_07775	ENOG4105DE4	1-phosphofructokinase
GII80_07780	ENOG4105DM4	PTS System
GII80_07785	ENOG4105C3F	Signal peptidase i
GII80_07795	ENOG4105C5H	ABC transporter
GII80_07800	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GII80_07825	ENOG4105BZU	Histidine kinase
GII80_07835	ENOG4107ZYR	domain protein
GII80_07845	ENOG4105CN5	Metallo-Beta-Lactamase
GII80_07855	ENOG4108X4Q	Hydrolase
GII80_07860	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GII80_07880	ENOG4105CPP	Dehydrogenase, E1 component
GII80_07885	ENOG4105C7S	Dehydrogenase
GII80_07890	ENOG4107QN2	dihydrolipoyl dehydrogenase
GII80_07905	ENOG4105CXN	decarboxylase
GII80_07910	ENOG4105WBI	UPF0223 protein
GII80_07925	ENOG4105ECY	inositol monophosphatase
GII80_07935	ENOG4105JQZ	Methyltransferase
GII80_07975	ENOG4105CI3	gtp-binding protein typa
GII80_07980	ENOG4105QA2	
GII80_07995	ENOG4108IAB	Phoh family
GII80_08005	ENOG4105CSV	Glutaminase
GII80_08010	ENOG4105ZPI	UPF0358 protein
GII80_08015	ENOG4105CNI	cell division protein FtsW
GII80_08020	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
GII80_08030	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GII80_08040	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GII80_08045	ENOG4105CCU	oxidase (Subunit III)
GII80_08050	ENOG41064X9	cytochrome C oxidase subunit IV
GII80_08065	ENOG41080XQ	Signal transduction protein with cbs domains
GII80_08070	ENOG4106UY4	Inherit from COG: Scp-like extracellular
GII80_08090	ENOG4105WUC	UPF0298 protein
GII80_08095	ENOG4106H78	methyltransferase
GII80_08100	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GII80_08105	ENOG4105H20	Sporulation integral membrane protein YlbJ
GII80_08110	ENOG4105D78	K07001 NTE family protein
GII80_08115	ENOG41063PX	domain protein
GII80_08120	ENOG4105CDE	UPF0348 protein
GII80_08130	ENOG4105KNH	Nucleic acid-binding protein
GII80_08135	ENOG41067VY	50S ribosomal protein L32
GII80_08160	ENOG4108V6E	Cell division protein mraZ
GII80_08165	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GII80_08175	ENOG4105CJN	penicillin-binding protein
GII80_08180	ENOG4105CJN	penicillin-binding protein
GII80_08185	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GII80_08190	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GII80_08195	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GII80_08200	ENOG4105CNI	cell division protein FtsW
GII80_08205	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GII80_08210	ENOG4105D4A	Cell wall formation (By similarity)
GII80_08215	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
GII80_08220	ENOG4108R2U	division initiation protein
GII80_08230	ENOG4105K67	small basic protein
GII80_08235	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GII80_08240	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GII80_08250	ENOG4105FFI	sigma-e processing peptidase spoiiga
GII80_08255	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GII80_08265	ENOG4105DKW	ABC transporter
GII80_08275	ENOG4105WR5	sporulation protein, YlmC YmxH family
GII80_08280	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GII80_08285	ENOG4105DFA	alanine racemase domain protein
GII80_08290	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
GII80_08295	ENOG41067XK	integral membrane protein
GII80_08300	ENOG4105DBK	s4 domain protein
GII80_08310	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GII80_08320	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GII80_08325	ENOG4105C34	Pseudouridine synthase
GII80_08330	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
GII80_08340	ENOG4105CXT	aspartate transcarbamylase
GII80_08350	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GII80_08355	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GII80_08360	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
GII80_08365	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
GII80_08370	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GII80_08375	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GII80_08380	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GII80_08390	ENOG4107S4M	Sulfate adenylate transferase
GII80_08395	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GII80_08400	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GII80_08405	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
GII80_08410	ENOG41087GM	Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein
GII80_08415	ENOG4105F23	Fibronectin-binding protein
GII80_08425	ENOG4105DSJ	YicC domain protein
GII80_08430	ENOG4105KC4	UPF0296 protein
GII80_08435	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GII80_08445	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GII80_08450	ENOG4105C25	Primosomal protein n'
GII80_08455	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GII80_08460	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GII80_08465	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GII80_08470	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GII80_08475	ENOG4108ZF3	Phosphatase
GII80_08480	ENOG4105D9P	serine threonine protein kinase
GII80_08485	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GII80_08490	ENOG4105DJV	ribulose-phosphate 3-epimerase
GII80_08495	ENOG4105FJ0	thiamine
GII80_08505	ENOG4105VB9	50S ribosomal protein l28
GII80_08510	ENOG4108ZAA	Alkaline-shock protein
GII80_08515	ENOG4105DP4	dak2 domain fusion protein ylov
GII80_08525	ENOG4105EJQ	L-serine dehydratase
GII80_08530	ENOG4105CB5	ATP-dependent DNA helicase recG
GII80_08535	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
GII80_08545	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GII80_08550	ENOG4105CHR	reductase
GII80_08555	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GII80_08560	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GII80_08565	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GII80_08570	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GII80_08580	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
GII80_08590	ENOG4105K5M	30s ribosomal protein S16
GII80_08595	ENOG4108BW8	UPF0109 protein
GII80_08605	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GII80_08610	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GII80_08615	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GII80_08620	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GII80_08625	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GII80_08635	ENOG4105VM1	flagellar
GII80_08640	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GII80_08645	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GII80_08650	ENOG4105C79	DNA protecting protein DprA
GII80_08655	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GII80_08660	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
GII80_08665	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GII80_08670	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GII80_08675	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GII80_08685	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GII80_08690	ENOG4108ZC9	flagellar basal-body rod protein flgc
GII80_08695	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GII80_08700	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GII80_08705	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GII80_08720	ENOG4106YF4	Flagellar biosynthesis chaperone
GII80_08730	ENOG410696Y	Flagellar hook-length control protein
GII80_08735	ENOG410822I	Flagellar hook capping protein
GII80_08740	ENOG4108JQA	flagellar
GII80_08745	ENOG41068WV	flagellar FlbD family protein
GII80_08755	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GII80_08760	ENOG4105DD5	Flagellar motor switch protein
GII80_08765	ENOG4107YTP	response regulator receiver protein
GII80_08775	ENOG4105CN7	Flagellar biosynthetic protein FliP
GII80_08780	ENOG4105VS8	Flagellar biosynthetic protein fliq
GII80_08785	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GII80_08790	ENOG4105D00	flagellar biosynthetic protein flhB
GII80_08795	ENOG4105D7B	Flagellar biosynthesis protein flha
GII80_08800	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GII80_08810	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GII80_08815	ENOG4105CBS	Chea signal transduction histidine kinase
GII80_08820	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
GII80_08835	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GII80_08845	ENOG4105CE9	30S ribosomal protein S2
GII80_08850	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GII80_08860	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GII80_08865	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GII80_08870	ENOG4105KNE	Phosphatidate cytidylyltransferase
GII80_08880	ENOG4105DZP	Membrane-associated zinc metalloprotease
GII80_08885	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GII80_08890	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GII80_08895	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GII80_08900	ENOG4105CHV	Transcription elongation factor NusA
GII80_08905	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
GII80_08910	ENOG4105VHM	ribosomal protein
GII80_08915	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GII80_08920	ENOG4105W7A	Protein of unknown function (DUF503)
GII80_08925	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GII80_08930	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GII80_08935	ENOG4105DTN	riboflavin biosynthesis protein ribF
GII80_08940	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GII80_08945	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GII80_08955	ENOG4105C1V	Peptidase, M16
GII80_08965	ENOG4105E35	Dipicolinate synthase subunit A
GII80_08970	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
GII80_08975	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GII80_08985	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GII80_08995	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
GII80_09005	ENOG4105CNU	cell division protein FtsK
GII80_09010	ENOG4105FDP	GntR family transcriptional regulator
GII80_09030	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
GII80_09035	ENOG4105XZV	Protein of unknown function (DUF3243)
GII80_09050	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GII80_09055	ENOG4105CEV	competence damage-inducible protein
GII80_09065	ENOG4108A04	Beta-lactamase
GII80_09070	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
GII80_09075	ENOG4105D48	metallophosphoesterase
GII80_09080	ENOG4105MCT	stage V sporulation protein S
GII80_09090	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GII80_09095	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GII80_09110	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GII80_09115	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GII80_09125	ENOG4105IIP	Membrane
GII80_09130	ENOG4105W1N	transcriptional regulator
GII80_09135	ENOG4108151	Beta-lactamase domain protein
GII80_09145	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GII80_09155	ENOG4107QKG	PfaD family
GII80_09160	ENOG41062T2	Acyl carrier protein
GII80_09165	ENOG4108MH3	Polyketide beta-ketoacyl acyl carrier protein synthase
GII80_09170	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
GII80_09175	ENOG4108MGH	Enoyl-CoA hydratase
GII80_09180	ENOG4108KQ6	Enoyl-CoA hydratase
GII80_09185	ENOG4105C0W	non-ribosomal peptide synthetase
GII80_09190	ENOG4107SQU	synthase
GII80_09200	ENOG4105C0W	non-ribosomal peptide synthetase
GII80_09210	ENOG4106A3M	Cytochrome p-450
GII80_09225	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GII80_09230	ENOG4105K7W	phage-related replication protein
GII80_09235	ENOG4108X3M	OsmC Ohr family protein
GII80_09240	ENOG410814C	multidrug resistance protein
GII80_09260	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GII80_09265	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GII80_09280	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
GII80_09285	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GII80_09290	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GII80_09295	ENOG4105U6W	MutT NUDIX family protein
GII80_09300	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GII80_09305	ENOG4106F1P	AAA ATPase, central domain protein
GII80_09310	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GII80_09315	ENOG4105CXI	aluminum resistance protein
GII80_09320	ENOG4105KV4	Transcriptional regulator
GII80_09325	ENOG4105C5F	glutamine synthetase
GII80_09330	ENOG41079P0	
GII80_09350	ENOG4107AUC	
GII80_09385	ENOG410907G	
GII80_09390	ENOG4105CT4	transporter
GII80_09395	ENOG4105DSG	hydrolase family 43
GII80_09400	ENOG4105E2R	ROK family
GII80_09405	ENOG4105C93	Xylose Isomerase
GII80_09410	ENOG4105CMG	Carbohydrate kinase
GII80_09420	ENOG4107Y9E	nuclease
GII80_09425	ENOG4105C54	Major Facilitator superfamily
GII80_09430	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GII80_09440	ENOG4107YUK	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GII80_09455	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GII80_09510	ENOG4108Q8B	Spore germination protein
GII80_09515	ENOG4108NHD	germination protein
GII80_09530	ENOG4105FVX	
GII80_09540	ENOG4105K7W	phage-related replication protein
GII80_09550	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
GII80_09555	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GII80_09565	ENOG4108SVB	resolvase
GII80_09570	ENOG4105VPS	UPF0291 protein
GII80_09575	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GII80_09595	ENOG4107QIV	Cytochrome c biogenesis protein
GII80_09620	ENOG4107DZX	Small, acid-soluble spore protein P
GII80_09630	ENOG4108I0Z	Aconitate hydratase
GII80_09635	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII80_09650	ENOG41067CD	Small, acid-soluble spore protein Tlp
GII80_09660	ENOG4105MI2	
GII80_09665	ENOG4105W8X	HesB YadR YfhF-family protein
GII80_09670	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GII80_09675	ENOG4105K4P	CoA-binding domain protein
GII80_09680	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GII80_09700	ENOG4107QWR	cellulase (EC 3.2.1.4)
GII80_09710	ENOG4108MYR	Secreted protein
GII80_09715	ENOG4107SYN	Glycosyl hydrolases family 43
GII80_09725	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GII80_09730	ENOG4107T5V	SNARE associated Golgi
GII80_09740	ENOG4107QX3	carboxylase
GII80_09745	ENOG4105E39	Enoyl-CoA hydratase
GII80_09750	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
GII80_09755	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
GII80_09760	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GII80_09765	ENOG4105CEY	Amp-dependent synthetase and ligase
GII80_09770	ENOG4105C1G	acyl-Coa dehydrogenase
GII80_09785	ENOG4105F32	YngK protein
GII80_09790	ENOG4106U2H	Protein of unknown function (DUF1360)
GII80_09800	ENOG4105CEY	Amp-dependent synthetase and ligase
GII80_09805	ENOG4105C0W	non-ribosomal peptide synthetase
GII80_09815	ENOG4105C0W	non-ribosomal peptide synthetase
GII80_09820	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
GII80_09825	ENOG4108N2V	aldose 1-epimerase
GII80_09830	ENOG4107QJQ	Mate efflux family protein
GII80_09855	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GII80_09860	ENOG4105SKE	transcriptional Regulator LysR family
GII80_09865	ENOG4105CB2	alcohol dehydrogenase
GII80_09870	ENOG4105BZ8	glutamate synthase
GII80_09875	ENOG4105CBC	glutamate synthase
GII80_09880	ENOG4105C5Q	Transcriptional regulator
GII80_09885	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GII80_09890	ENOG4105II7	pyrroline-5-carboxylate reductase
GII80_09910	ENOG4108UB7	
GII80_09915	ENOG41068WN	
GII80_09920	ENOG4105IE8	Alpha-ketoglutarate permease
GII80_09925	ENOG4107U6E	carbohydrate kinase FGGY
GII80_09930	ENOG4108M3J	Dehydrogenase
GII80_09935	ENOG4108J2R	molybdopterin oxidoreductase
GII80_09965	ENOG4105EC8	Methyl-accepting chemotaxis
GII80_09975	ENOG4108YQE	rare lipoprotein a
GII80_09980	ENOG4105XPP	Protein of unknown function (DUF1275)
GII80_09985	ENOG4108NR7	pectate lyase
GII80_09990	ENOG4108RAV	Conserved protein
GII80_10000	ENOG4105F0F	Oxalate decarboxylase
GII80_10015	ENOG4105EPI	acetyltransferase, (GNAT) family
GII80_10035	ENOG41073R8	VanW family
GII80_10045	ENOG4105VMP	Transcriptional regulator
GII80_10050	ENOG4105NX3	Membrane
GII80_10060	ENOG4108Q5Y	Membrane
GII80_10070	ENOG4108V4B	ThiJ pfpI
GII80_10075	ENOG4108J4B	Beta-lactamase
GII80_10100	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GII80_10105	ENOG4107T94	Endo-14-beta-xylanase
GII80_10110	ENOG4105YB8	TM2 domain containing protein
GII80_10115	ENOG4108IMY	Transcriptional regulator
GII80_10130	ENOG4108RAV	Conserved protein
GII80_10135	ENOG41079CX	
GII80_10165	ENOG410780I	phosphoprotein phosphatase activity
GII80_10190	ENOG4105DB4	
GII80_10210	ENOG4106ANW	SMI1_KNR4
GII80_10235	ENOG4108Z7R	Chaperone CsaA
GII80_10240	ENOG4105FTV	AraC Family Transcriptional Regulator
GII80_10245	ENOG4108HJF	gCN5-related N-acetyltransferase
GII80_10255	ENOG4108W8B	Beta-lactamase domain protein
GII80_10265	ENOG4105D29	Helix-turn-helix type 11 domain protein
GII80_10275	ENOG4105KTU	Transcriptional regulator, arsr family
GII80_10285	ENOG4108SJC	Membrane
GII80_10305	ENOG4105ECK	Fatty Acid Desaturase
GII80_10310	ENOG4108ZGX	Histidine kinase
GII80_10315	ENOG4108S01	response regulator
GII80_10320	ENOG41069ER	domain protein
GII80_10325	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GII80_10335	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GII80_10340	ENOG4105SCY	DNAK suppressor
GII80_10380	ENOG4105C26	Dehydrogenase
GII80_10385	ENOG4105EWU	Squalene--hopene cyclase
GII80_10390	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GII80_10395	ENOG4105C8J	)-transporter
GII80_10400	ENOG4105C09	Bile acid
GII80_10405	ENOG4105C7S	Dehydrogenase
GII80_10415	ENOG4107T89	von Willebrand factor, type A
GII80_10420	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
GII80_10430	ENOG4105K4H	Nlp p60 protein
GII80_10435	ENOG41087PP	glycosyltransferase MGT family
GII80_10445	ENOG4107QMU	Mate efflux family protein
GII80_10450	ENOG4106SCS	STAS domain
GII80_10470	ENOG4105FR1	rard protein
GII80_10485	ENOG4105C6Z	Gluconate
GII80_10490	ENOG41090U3	tautomerase
GII80_10505	ENOG4105FBA	Phospholipase Carboxylesterase
GII80_10520	ENOG4105E1V	na solute symporter
GII80_10540	ENOG4108VXD	carboxy-peptidase
GII80_10545	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GII80_10555	ENOG4106Z5R	
GII80_10560	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GII80_10590	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GII80_10595	ENOG4108TSC	N-acetyltransferase
GII80_10600	ENOG4107S4Y	M20 DapE family protein YgeY
GII80_10615	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GII80_10655	ENOG4107T32	3-phytase (EC 3.1.3.8)
GII80_10660	ENOG4105C5E	polysaccharide biosynthesis protein
GII80_10670	ENOG4106Y37	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
GII80_10770	ENOG4105FTQ	Dna gyrase
GII80_10775	ENOG4107YUK	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GII80_10780	ENOG4106ITI	Glutaredoxin
GII80_10800	ENOG4107S45	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GII80_10805	ENOG4107S45	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GII80_10810	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
GII80_10900	ENOG4105DVF	Cytosine-specific methyltransferase
GII80_10910	ENOG4106210	phosphatase activity
GII80_10945	ENOG4106J9J	DNA polymerase
GII80_10955	ENOG4106IVX	
GII80_10960	ENOG4106PTB	DnaB-like helicase C terminal domain
GII80_10970	ENOG41088HM	
GII80_10975	ENOG4106YR8	
GII80_11005	ENOG4105K7W	phage-related replication protein
GII80_11020	ENOG4108RAV	Conserved protein
GII80_11025	ENOG4108J9Q	DNA ligase
GII80_11080	ENOG4105GJD	protein, conserved in bacteria
GII80_11110	ENOG4108ZUE	Phage regulatory protein rha
GII80_11205	ENOG4107D0N	
GII80_11220	ENOG4106HHG	
GII80_11255	ENOG4106J6E	
GII80_11260	ENOG4107NTZ	
GII80_11265	ENOG41063R6	
GII80_11275	ENOG4108NE4	
GII80_11300	ENOG41067QW	Transcriptional regulator
GII80_11310	ENOG4105ZUG	
GII80_11315	ENOG4105K70	DNA-binding protein
GII80_11330	ENOG4106QVS	
GII80_11425	ENOG41068G1	
GII80_11480	ENOG4105E4C	Lytic transglycosylase catalytic
GII80_11500	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
GII80_11505	ENOG4105MYH	
GII80_11515	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
GII80_11535	ENOG4107R0E	Glycosyl transferase, family 2
GII80_11560	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GII80_11590	ENOG4105UA4	acetyltransferase
GII80_11600	ENOG41090AA	
GII80_11605	ENOG4106BHF	
GII80_11625	ENOG4107Y9E	nuclease
GII80_11635	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
GII80_11650	ENOG4106RPI	
GII80_11665	ENOG4105C5E	polysaccharide biosynthesis protein
GII80_11670	ENOG4105E0X	reductase
GII80_11675	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GII80_11695	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
GII80_11700	ENOG41090WU	lipolytic protein G-D-S-L family
GII80_11705	ENOG4108KF3	Electron transport protein SCO1 SenC
GII80_11715	ENOG4105C7B	Threonine dehydratase
GII80_11725	ENOG4108UT2	hemolysin iii
GII80_11735	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
GII80_11740	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GII80_11755	ENOG4107YX5	Pfam:DUF548
GII80_11760	ENOG4108Y6J	UPF0403 protein
GII80_11765	ENOG4105C01	Dihydroxy-acid dehydratase
GII80_11780	ENOG4108V06	Glutathione peroxidase
GII80_11785	ENOG4105CVG	Homoserine O-transsuccinylase
GII80_11830	ENOG41081VK	Ribonuclease
GII80_11855	ENOG410890F	Dynamin family
GII80_11870	ENOG41065KQ	synthase
GII80_11875	ENOG4105C2W	permease
GII80_11880	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
GII80_11885	ENOG4105CTD	carboxy-peptidase
GII80_11890	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
GII80_11895	ENOG4108UHU	Aldolase
GII80_11900	ENOG4105D7K	pfkb domain protein
GII80_11905	ENOG4108M60	Transcriptional regulator
GII80_11915	ENOG4105CHR	reductase
GII80_11920	ENOG4105DVT	helicase
GII80_11935	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GII80_11950	ENOG4108UKS	UPF0398 protein
GII80_11965	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
GII80_11970	ENOG4108I5C	dEAD DEAH box helicase
GII80_12020	ENOG4105BZ4	penicillin-binding protein
GII80_12030	ENOG4105CSM	endonuclease III
GII80_12040	ENOG4105C5S	asparaginyl-tRNA synthetase
GII80_12045	ENOG4105CHM	Aminotransferase
GII80_12055	ENOG4105YAC	
GII80_12060	ENOG4105DVT	helicase
GII80_12065	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GII80_12070	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GII80_12075	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GII80_12080	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GII80_12085	ENOG4105DJ0	Poly(A) Polymerase
GII80_12090	ENOG4105CPK	Glycosyl transferase (Group 1
GII80_12095	ENOG4105FJR	Lmbe family
GII80_12100	ENOG4108Z5K	methylglyoxal synthase
GII80_12105	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GII80_12110	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
GII80_12115	ENOG4108JYZ	YitT family
GII80_12135	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GII80_12155	ENOG41068YB	TPR repeat-containing protein
GII80_12160	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GII80_12170	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GII80_12180	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GII80_12185	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
GII80_12195	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GII80_12200	ENOG4105CRQ	synthase (Component I)
GII80_12205	ENOG4105KHN	chorismate mutase
GII80_12210	ENOG4105D49	3-dehydroquinate synthase
GII80_12215	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GII80_12220	ENOG4105BZU	Histidine kinase
GII80_12225	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GII80_12230	ENOG4105EAH	synthase
GII80_12235	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GII80_12240	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
GII80_12250	ENOG4105EUJ	GTP cyclohydrolase i
GII80_12255	ENOG4105K70	DNA-binding protein
GII80_12260	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
GII80_12275	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GII80_12280	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GII80_12285	ENOG41065D1	
GII80_12290	ENOG4105S2F	
GII80_12305	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
GII80_12310	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GII80_12315	ENOG4105CAT	Cytidine monophosphate kinase
GII80_12330	ENOG4105MSI	germination protein ypeb
GII80_12340	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
GII80_12345	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
GII80_12360	ENOG4107RGJ	metallophosphoesterase
GII80_12375	ENOG4105I7S	Abortive infection protein
GII80_12380	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GII80_12385	ENOG4105T7X	
GII80_12395	ENOG4108SAX	Membrane
GII80_12400	ENOG4108JQ1	Dehydrogenase
GII80_12405	ENOG4105FF2	Type I DHQase
GII80_12420	ENOG4105BZU	Histidine kinase
GII80_12425	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GII80_12430	ENOG4105CRE	cytochrome C
GII80_12435	ENOG4107TWT	Cytochrome c biogenesis protein
GII80_12445	ENOG4105FE9	pseudouridine synthase
GII80_12455	ENOG4108JIC	nucleoside recognition domain protein
GII80_12460	ENOG4105DZ1	carboxypeptidase
GII80_12470	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GII80_12475	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
GII80_12490	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GII80_12495	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GII80_12500	ENOG4108R6K	riboflavin synthase, subunit alpha
GII80_12505	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GII80_12515	ENOG4105C3F	Signal peptidase i
GII80_12525	ENOG4105VES	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII80_12540	ENOG4107ZE5	PPIases accelerate the folding of proteins
GII80_12545	ENOG4105PTM	secreted protein
GII80_12550	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GII80_12560	ENOG4105G6R	Stage v sporulation protein ae
GII80_12570	ENOG4105CZ3	stage V sporulation protein ad
GII80_12575	ENOG41090VF	Stage v sporulation protein ac
GII80_12590	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GII80_12595	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
GII80_12600	ENOG41082AN	stage II sporulation protein
GII80_12605	ENOG4105DZ1	carboxypeptidase
GII80_12610	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
GII80_12615	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GII80_12620	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GII80_12630	ENOG4105I3K	Ferric uptake regulator, Fur family
GII80_12635	ENOG4105MZ9	stage II sporulation protein m
GII80_12650	ENOG4105DFD	Na H antiporter
GII80_12655	ENOG4108IJ0	Aspartate ammonia-lyase
GII80_12660	ENOG4105HDK	L-asparaginase
GII80_12665	ENOG4108IMY	Transcriptional regulator
GII80_12675	ENOG4108YZ4	nudix hydrolase
GII80_12685	ENOG4105CPC	Aldo Keto reductase
GII80_12705	ENOG4106HZJ	
GII80_12710	ENOG4105RHY	Pfam:UPF0157
GII80_12715	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
GII80_12720	ENOG4108XET	gCN5-related N-acetyltransferase
GII80_12730	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GII80_12740	ENOG4105E5W	Transporter
GII80_12745	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
GII80_12760	ENOG4108IXY	short-chain dehydrogenase reductase
GII80_12765	ENOG41069FQ	Metallo-beta-lactamase superfamily
GII80_12770	ENOG4105II7	pyrroline-5-carboxylate reductase
GII80_12780	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GII80_12795	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GII80_12800	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GII80_12805	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GII80_12810	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GII80_12820	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
GII80_12825	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
GII80_12830	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GII80_12835	ENOG4108HNZ	carboxyl transferase
GII80_12840	ENOG4108ZVT	methylmalonyl-coA epimerase
GII80_12850	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
GII80_12855	ENOG4108QEG	Membrane
GII80_12860	ENOG4105CDA	abc transporter atp-binding protein
GII80_12865	ENOG4105E5Q	amino acid AbC transporter
GII80_12870	ENOG4108HW3	(ABC) transporter
GII80_12875	ENOG4108Y6J	UPF0403 protein
GII80_12880	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
GII80_12895	ENOG4105C7S	Dehydrogenase
GII80_12900	ENOG4105CPP	Dehydrogenase, E1 component
GII80_12915	ENOG4105CKM	Branched-chain carboxylic acid kinase
GII80_12920	ENOG4107RDP	Dehydrogenase
GII80_12930	ENOG4108JUB	Transcriptional regulator
GII80_12935	ENOG4106CCJ	Protein of unknown function (DUF2627)
GII80_12940	ENOG4105CR4	methylisocitrate lyase
GII80_12945	ENOG4105DXD	2-methylcitrate dehydratase
GII80_12955	ENOG4105C1G	acyl-Coa dehydrogenase
GII80_12960	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GII80_12970	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GII80_12975	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GII80_12990	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GII80_12995	ENOG4107QQR	Sporulation
GII80_13000	ENOG4105S1Z	Stage IV sporulation protein B
GII80_13005	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GII80_13010	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GII80_13015	ENOG4105DX0	Hemolysin A
GII80_13025	ENOG4105CTB	Polyprenyl synthetase
GII80_13030	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GII80_13035	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GII80_13040	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GII80_13045	ENOG4105M7K	Involved in the transcription termination process (By similarity)
GII80_13050	ENOG4108ZSR	alkaline shock protein
GII80_13055	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GII80_13075	ENOG410644B	Stage III sporulation protein af
GII80_13085	ENOG4105KQ4	Stage iii sporulation protein ad
GII80_13090	ENOG4108CQH	stage III sporulation protein AC
GII80_13095	ENOG4105KR5	Stage iii sporulation protein
GII80_13100	ENOG4105CD2	stage iii sporulation protein aa
GII80_13110	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GII80_13115	ENOG4105DC7	peptidase M24
GII80_13120	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GII80_13130	ENOG4105CBJ	Metal-dependent enzyme
GII80_13145	ENOG4105KST	dependent repressor
GII80_13150	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
GII80_13155	ENOG4105WZW	rhodanese family
GII80_13160	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII80_13165	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII80_13170	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GII80_13175	ENOG4105C0D	helicase
GII80_13190	ENOG4108IMY	Transcriptional regulator
GII80_13200	ENOG4105VFR	signal peptidase
GII80_13260	ENOG4105C37	(CBS) domain
GII80_13285	ENOG4105C5X	domain protein
GII80_13310	ENOG4105E0M	Sulfatase
GII80_13325	ENOG4107ZXI	Rhomboid family
GII80_13335	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GII80_13340	ENOG4105WDJ	50S ribosomal protein L33
GII80_13360	ENOG41068DG	YceG-like family
GII80_13365	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GII80_13370	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GII80_13375	ENOG4105E2Z	phosphate ABC transporter (Permease
GII80_13380	ENOG4105C8U	phosphate abc transporter
GII80_13385	ENOG4105CVA	phosphate
GII80_13390	ENOG4107RF6	penicillin-binding protein
GII80_13400	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GII80_13405	ENOG4105SXS	Protein of unknown function (DUF456)
GII80_13425	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GII80_13430	ENOG41063Y9	
GII80_13435	ENOG4108U5J	'-nucleotidase
GII80_13440	ENOG4105N80	Ferric uptake regulator, Fur family
GII80_13445	ENOG4108JYZ	YitT family
GII80_13450	ENOG41069ZM	Protein of unknown function (DUF2624)
GII80_13455	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GII80_13470	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GII80_13475	ENOG4105EGD	dinuclear metal center protein, YbgI family
GII80_13490	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GII80_13495	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GII80_13500	ENOG41082VT	Uncharacterized BCR, YaiI/YqxD family COG1671
GII80_13505	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GII80_13515	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GII80_13520	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
GII80_13525	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
GII80_13535	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GII80_13540	ENOG4105KG3	cytidine deaminase
GII80_13545	ENOG4107YR5	Diacylglycerol kinase
GII80_13550	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GII80_13555	ENOG4105CTJ	Metal Dependent Phosphohydrolase
GII80_13560	ENOG4105C9A	Phoh family
GII80_13565	ENOG4105EI1	sporulation protein yqfd
GII80_13570	ENOG41068P3	sporulation protein YqfC
GII80_13580	ENOG4105DI5	UPF0365 protein
GII80_13585	ENOG4105F7J	membrane-bound serine protease
GII80_13590	ENOG4105KTH	gatB Yqey
GII80_13605	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GII80_13610	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GII80_13615	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GII80_13625	ENOG4105CFG	Acts as a chaperone (By similarity)
GII80_13630	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII80_13635	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
GII80_13640	ENOG4105CSA	Coproporphyrinogen iii oxidase
GII80_13645	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GII80_13655	ENOG4108ZRV	stage ii sporulation protein p
GII80_13660	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
GII80_13665	ENOG41082YS	Binds directly to 16S ribosomal RNA
GII80_13670	ENOG4105TQK	DNA polymerase iii, delta' subunit
GII80_13685	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
GII80_13690	ENOG4108UK2	deaminase
GII80_13695	ENOG4105KQC	Competence protein
GII80_13705	ENOG4108D32	Methyltransferase
GII80_13715	ENOG4108WF2	Metal Dependent Phosphohydrolase
GII80_13720	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GII80_13725	ENOG410812S	Rna-binding protein
GII80_13730	ENOG4105E2X	shikimate dehydrogenase
GII80_13735	ENOG4105CQW	ribosome biogenesis GTPase YqeH
GII80_13740	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
GII80_13755	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
GII80_13760	ENOG41080BT	SNARE associated Golgi
GII80_13775	ENOG4105WFK	nuclease
GII80_13785	ENOG4107Y5K	Resolvase
GII80_13790	ENOG4108UXE	Protein tyrosine phosphatase
GII80_13795	ENOG4105D6J	arsenicaL-resistance protein
GII80_13800	ENOG4108YZ3	Glyoxalase Bleomycin resistance protein (Dioxygenase
GII80_13805	ENOG41085FC	arsR family transcriptional regulator
GII80_13835	ENOG41064HX	Suppressor of fused protein (SUFU)
GII80_13855	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
GII80_13890	ENOG410906S	phage-like element pbsx protein xkdt
GII80_13895	ENOG41066EA	baseplate J family protein
GII80_13900	ENOG4105MFU	Protein of unknown function (DUF2634)
GII80_13910	ENOG4105X7F	
GII80_13915	ENOG4108WZM	domain protein
GII80_13920	ENOG4108FKH	Transglycosylase SLT domain
GII80_13930	ENOG4105MTC	XkdN-like protein
GII80_13945	ENOG4105FR7	XkdM protein, phage-like element PBSX
GII80_13950	ENOG4105PQS	phage protein
GII80_13965	ENOG41060SN	
GII80_14000	ENOG4106CGH	Phage Mu protein F like protein
GII80_14005	ENOG4108MDF	Phage Portal Protein
GII80_14010	ENOG4105IG6	Phage terminase, large subunit
GII80_14030	ENOG4106129	
GII80_14040	ENOG4105QBX	endodeoxyribonuclease RusA
GII80_14060	ENOG4108PNI	recT protein
GII80_14065	ENOG4108NF7	phage-type endonuclease
GII80_14095	ENOG4106A7E	Transcriptional regulator
GII80_14100	ENOG41067QW	Transcriptional regulator
GII80_14110	ENOG4105KR8	Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GII80_14145	ENOG4108SWU	Histidine kinase
GII80_14150	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GII80_14155	ENOG4105DHF	Membrane
GII80_14165	ENOG4108UYN	gCN5-related N-acetyltransferase
GII80_14170	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GII80_14175	ENOG41068VA	
GII80_14180	ENOG41087NI	Sulfite exporter TauE/SafE
GII80_14185	ENOG4105VFE	sira family
GII80_14190	ENOG4107TPS	domain protein
GII80_14200	ENOG4105VFE	sira family
GII80_14210	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
GII80_14215	ENOG4105XTG	Pfam:DUF156
GII80_14225	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
GII80_14235	ENOG41090E6	transcriptional regulator MERR family
GII80_14250	ENOG4105C37	(CBS) domain
GII80_14265	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
GII80_14270	ENOG4105H3G	oxidoreductase
GII80_14275	ENOG4105PGM	cation diffusion facilitator family transporter
GII80_14280	ENOG41090U3	tautomerase
GII80_14300	ENOG4105KMT	branched-chain amino acid
GII80_14305	ENOG4108UMN	azlc family
GII80_14310	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
GII80_14315	ENOG41067XF	inhibitor
GII80_14335	ENOG41064BW	Protein of unknown function (DUF2568)
GII80_14345	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
GII80_14350	ENOG4105EA8	2-Nitropropane dioxygenase
GII80_14355	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GII80_14375	ENOG4108MEK	Metal-binding protein YodA
GII80_14380	ENOG410904A	RNA polymerase
GII80_14385	ENOG4105CPC	Aldo Keto reductase
GII80_14395	ENOG4108KAM	Transcriptional regulator
GII80_14400	ENOG4105C7F	AcnD-accessory protein PrpF
GII80_14405	ENOG41083Q9	chitosanase
GII80_14410	ENOG4105X5K	response regulator receiver protein
GII80_14415	ENOG4108VQT	Alpha beta hydrolase fold protein
GII80_14420	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
GII80_14425	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
GII80_14435	ENOG4105Z0X	Glyoxalase Bleomycin resistance protein (Dioxygenase
GII80_14445	ENOG4105PGS	Spore coat protein
GII80_14450	ENOG4105E2A	Dehydrogenase
GII80_14465	ENOG4105VUF	Transcriptional regulator
GII80_14475	ENOG4105DQ4	alcohol dehydrogenase
GII80_14480	ENOG4108Z0Z	intracellular protease Pfpi family
GII80_14485	ENOG4108HKT	sucrose-6-phosphate hydrolase
GII80_14490	ENOG4105F3R	pts system mannose fructose sorbose family iid
GII80_14495	ENOG4105ETZ	PTS System
GII80_14500	ENOG4108IQ3	PTS system
GII80_14505	ENOG4105YHU	PTS system
GII80_14510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GII80_14520	ENOG4105C85	amino acid
GII80_14525	ENOG4105N14	lysine exporter protein LysE YggA
GII80_14530	ENOG4108NGU	Transcriptional regulator
GII80_14535	ENOG4105JVQ	RNA Polymerase
GII80_14540	ENOG4108P49	AntiSigma factor
GII80_14545	ENOG4105EXC	Acyl-transferase
GII80_14550	ENOG4105WDR	
GII80_14555	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GII80_14560	ENOG41082JN	Transcriptional regulator
GII80_14580	ENOG4105TMB	Formate nitrite transporter
GII80_14585	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
GII80_14590	ENOG4108JB9	formate dehydrogenase
GII80_14605	ENOG4105C28	cystathionine
GII80_14620	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
GII80_14635	ENOG4107XRG	penicillin-binding protein
GII80_14640	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GII80_14645	ENOG4105DBI	uridine monophosphokinase
GII80_14650	ENOG4105CFP	Peptidase U32
GII80_14655	ENOG4105XYU	peptidase (U32 family)
GII80_14660	ENOG4108VQJ	O-methyltransferase
GII80_14665	ENOG4105HHA	aminodeoxychorismate lyase
GII80_14670	ENOG4105VPH	UPF0473 protein
GII80_14675	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GII80_14680	ENOG4105VBH	UPF0297 protein
GII80_14685	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GII80_14690	ENOG4105C02	permease
GII80_14695	ENOG4105CDA	abc transporter atp-binding protein
GII80_14700	ENOG4105CT1	(ABC) transporter
GII80_14705	ENOG4105EAD	ABC transporter
GII80_14710	ENOG4105DRP	amino acid AbC transporter
GII80_14720	ENOG41060CR	
GII80_14730	ENOG4105C7H	Helicase, RecD TraA family
GII80_14740	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GII80_14745	ENOG4105C3J	Cysteine desulfurase
GII80_14755	ENOG4105D1H	recombination factor protein RarA
GII80_14760	ENOG4105CUZ	uba thif-type nad fad binding protein
GII80_14770	ENOG4105C9M	aspartyl-trna synthetase
GII80_14775	ENOG4105CUT	histidyl-tRNA synthetase
GII80_14785	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GII80_14795	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GII80_14800	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GII80_14805	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GII80_14810	ENOG41067VP	Protein of unknown function (DUF1049)
GII80_14815	ENOG4105NCW	Trka-c domain protein
GII80_14820	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GII80_14830	ENOG4105CKP	Polysaccharide Biosynthesis Protein
GII80_14835	ENOG4108QG2	Membrane
GII80_14840	ENOG4105NAP	
GII80_14845	ENOG4105VIE	preprotein translocase, subunit YajC
GII80_14850	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GII80_14855	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GII80_14860	ENOG41061AI	Protein of unknown function (DUF2905)
GII80_14865	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GII80_14870	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GII80_14880	ENOG4105IE8	Alpha-ketoglutarate permease
GII80_14885	ENOG4105CK5	oxidoreductase
GII80_14910	ENOG4105BZG	amino acid carrier protein
GII80_14915	ENOG4105CDY	transcriptional regulatory protein
GII80_14925	ENOG4106678	morphogenetic protein associated with SpoVID
GII80_14930	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GII80_14935	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GII80_14940	ENOG4108IYU	L-aspartate oxidase
GII80_14955	ENOG4105CQC	Prephenate dehydratase
GII80_14960	ENOG41090I5	UPF0735 ACT domain-containing protein
GII80_14965	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII80_14980	ENOG4105K46	50S ribosomal protein l27
GII80_14985	ENOG4105X36	(ribosomal) protein
GII80_14990	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GII80_15005	ENOG4107QMS	site-determining protein
GII80_15010	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GII80_15015	ENOG4105YHC	Rod shape-determining protein MreD
GII80_15020	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GII80_15025	ENOG4105DFF	Rod shape-determining protein mreb
GII80_15030	ENOG4105W5Q	DNA repair protein (RadC
GII80_15035	ENOG4108Z03	MAF-like protein
GII80_15045	ENOG4106A3R	peptidase
GII80_15050	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GII80_15055	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GII80_15065	ENOG4106AR7	Spore coat protein
GII80_15070	ENOG41068KH	stage VI sporulation protein D
GII80_15075	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GII80_15080	ENOG4105D52	delta-aminolevulinic acid dehydratase
GII80_15090	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GII80_15100	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GII80_15110	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GII80_15115	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GII80_15120	ENOG4108IUQ	atp-dependent protease
GII80_15125	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GII80_15130	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GII80_15140	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GII80_15145	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GII80_15150	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GII80_15155	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GII80_15160	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GII80_15165	ENOG4108ZP8	Acetolactate synthase small subunit
GII80_15170	ENOG4105C7K	acetolactate synthase
GII80_15180	ENOG4105I4A	GCN5-related N-acetyltransferase
GII80_15185	ENOG4107KM7	Heat induced stress protein YflT
GII80_15195	ENOG4105M59	Phosphodiesterase, mj0936 family
GII80_15200	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GII80_15205	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GII80_15210	ENOG4108XJQ	germination protein
GII80_15215	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GII80_15220	ENOG41067TZ	transcriptional regulator, MarR family
GII80_15225	ENOG4105PFC	Transcriptional regulator
GII80_15235	ENOG4105E33	succinate dehydrogenase
GII80_15245	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
GII80_15255	ENOG4105CFH	Aspartokinase
GII80_15260	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GII80_15265	ENOG4105K63	Thioredoxin
GII80_15275	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
GII80_15280	ENOG4105C10	Electron transfer flavoprotein
GII80_15285	ENOG4105BZJ	Electron transfer flavoprotein
GII80_15290	ENOG41060WC	Enoyl-CoA hydratase
GII80_15295	ENOG4107Z3H	Transcriptional regulator, TetR family
GII80_15300	ENOG4105CEY	Amp-dependent synthetase and ligase
GII80_15310	ENOG4105C98	muts2 protein
GII80_15315	ENOG4105DCG	PHP domain protein
GII80_15330	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GII80_15335	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GII80_15340	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GII80_15350	ENOG4108RWN	rrna methyltransferase
GII80_15355	ENOG41067MF	small acid-soluble spore protein
GII80_15365	ENOG4105CQB	FAD linked oxidase domain protein
GII80_15370	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GII80_15390	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
GII80_15395	ENOG4105DRS	transport system, permease
GII80_15410	ENOG4108MDK	Dehydrogenase
GII80_15420	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
GII80_15425	ENOG4105EF1	ribulokinase
GII80_15435	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
GII80_15440	ENOG4105CN9	Peptidase m42 family protein
GII80_15450	ENOG410696E	Membrane
GII80_15455	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GII80_15460	ENOG4105VJV	50s ribosomal protein L35
GII80_15465	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GII80_15475	ENOG41067MG	lrgb family
GII80_15485	ENOG4105DY9	regulatoR
GII80_15490	ENOG4108HRK	Histidine kinase
GII80_15495	ENOG4105U0R	haloacid dehalogenase-like hydrolase
GII80_15500	ENOG4105C22	threonyL-tRNA synthetase
GII80_15505	ENOG4108TDW	sporulation protein YtxC
GII80_15525	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GII80_15530	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
GII80_15535	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GII80_15540	ENOG4105KVH	Transcriptional regulator
GII80_15545	ENOG4105F27	Major Facilitator
GII80_15550	ENOG4105CV8	reductase
GII80_15555	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GII80_15565	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GII80_15570	ENOG4105C2M	dna polymerase I
GII80_15575	ENOG4105BZU	Histidine kinase
GII80_15580	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GII80_15585	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GII80_15590	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GII80_15595	ENOG4105BZN	citrate synthase
GII80_15605	ENOG4108REF	Sporulation integral membrane protein ytvi
GII80_15610	ENOG4105FS0	cytoplasmic membrane protein
GII80_15615	ENOG4105CA9	Pyruvate kinase
GII80_15620	ENOG4105CTQ	phosphohexokinase
GII80_15630	ENOG4108IEY	Carboxyl transferase domain
GII80_15635	ENOG4105C6K	Malic enzyme
GII80_15640	ENOG4105C0B	DNA polymerase III (alpha subunit)
GII80_15645	ENOG4105VV2	
GII80_15655	ENOG4106EVM	
GII80_15660	ENOG4105SFS	phosphoesterase RecJ domain protein
GII80_15675	ENOG410635A	Membrane
GII80_15680	ENOG4105CH2	amidohydrolase
GII80_15700	ENOG4105DEN	Luciferase family
GII80_15705	ENOG4105CDA	abc transporter atp-binding protein
GII80_15730	ENOG4108XSB	acetyltransferase, (GNAT) family
GII80_15735	ENOG4108KSA	LysR family transcriptional regulator
GII80_15740	ENOG4105E8R	UPF0173 metal-dependent hydrolase
GII80_15755	ENOG4105CH7	arginosuccinase
GII80_15760	ENOG4105CDH	Citrulline--aspartate ligase
GII80_15765	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
GII80_15770	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GII80_15785	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GII80_15790	ENOG4105KBJ	sporulation protein ytfj
GII80_15800	ENOG4105VK3	rdd domain containing protein
GII80_15805	ENOG4105D07	Signal peptide peptidase, SppA
GII80_15810	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GII80_15815	ENOG4105EFZ	amidohydrolase
GII80_15820	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GII80_15855	ENOG4105U5Y	Transcriptional regulator
GII80_15865	ENOG4105BZU	Histidine kinase
GII80_15875	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GII80_15880	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GII80_15890	ENOG4105F1V	Acetoin utilization protein
GII80_15895	ENOG4105W87	Cbs domain
GII80_15900	ENOG4105DGU	Histone deacetylase
GII80_15905	ENOG4105ER2	Ompa motb domain protein
GII80_15910	ENOG4107R0U	MotA TolQ exbB proton channel
GII80_15915	ENOG4105ETE	Transcriptional regulator (LacI family
GII80_15920	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GII80_15940	ENOG4105DFU	Cell wall formation (By similarity)
GII80_15950	ENOG4108VDD	TRNA binding domain protein
GII80_15970	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
GII80_15985	ENOG4105C6K	Malic enzyme
GII80_15990	ENOG4105C8F	Beta-lactamase domain protein
GII80_15995	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GII80_16005	ENOG4108V15	phosphotransferase enzyme family
GII80_16010	ENOG4108IUM	Glycogen debranching enzyme
GII80_16025	ENOG4107F58	2'-5' rna ligase
GII80_16030	ENOG4105C6T	cysteine synthase
GII80_16035	ENOG4107QSE	Dipeptidase
GII80_16040	ENOG4105C7N	Xanthine uracil vitamin C permease
GII80_16055	ENOG4105YW5	deoR family transcriptional regulator
GII80_16070	ENOG4105CBX	hi0933 family
GII80_16075	ENOG4105C94	Transporter
GII80_16085	ENOG4105MU9	integral membrane protein
GII80_16090	ENOG4105DDC	Oxidoreductase domain protein
GII80_16100	ENOG4105F5H	Glycosyl Hydrolase Family 88
GII80_16110	ENOG41075H3	AraC family transcriptional regulator
GII80_16120	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GII80_16130	ENOG4106A3M	Cytochrome p-450
GII80_16135	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GII80_16140	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GII80_16145	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GII80_16150	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GII80_16155	ENOG4108W8G	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity)
GII80_16160	ENOG4105NTD	Inherit from COG: Hydrolase
GII80_16175	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
GII80_16180	ENOG4105I1K	ABC transporter
GII80_16190	ENOG41085GJ	domain protein
GII80_16195	ENOG4105C8T	Leucyl-tRNA synthetase
GII80_16205	ENOG4105BZU	Histidine kinase
GII80_16210	ENOG410605W	Major Facilitator
GII80_16215	ENOG4106UBQ	
GII80_16225	ENOG4105C19	ABC transporter
GII80_16230	ENOG4105EWM	Histidine kinase
GII80_16240	ENOG4107R34	abc transporter permease protein
GII80_16245	ENOG4105C19	ABC transporter
GII80_16260	ENOG4105DVE	abc transporter atp-binding protein
GII80_16265	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
GII80_16280	ENOG4105N5T	Radical SAM Protein
GII80_16295	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
GII80_16300	ENOG4108Z0R	Transferase
GII80_16305	ENOG4105C85	amino acid
GII80_16310	ENOG4105CAQ	asparagine synthetase
GII80_16315	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GII80_16320	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GII80_16335	ENOG4105D2X	ABC transporter substrate-binding protein
GII80_16345	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
GII80_16360	ENOG4108RMU	ferritin dps family protein
GII80_16375	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GII80_16380	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GII80_16385	ENOG4108V2W	Carbonate dehydratase
GII80_16410	ENOG4105CC5	ABC transporter
GII80_16415	ENOG4105CC5	ABC transporter
GII80_16420	ENOG4105DIK	(ABC) transporter
GII80_16425	ENOG4105DSE	periplasmic solute binding protein
GII80_16430	ENOG4105DTQ	mandelate racemase muconate lactonizing
GII80_16435	ENOG4105CEY	Amp-dependent synthetase and ligase
GII80_16440	ENOG4108IPT	Naphthoate synthase
GII80_16445	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GII80_16450	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GII80_16455	ENOG4105E4F	Isochorismate synthase
GII80_16475	ENOG4108IAJ	Nad-dependent epimerase dehydratase
GII80_16480	ENOG4107SBE	Glycosyl transferase (Group 1
GII80_16495	ENOG4107SBE	Glycosyl transferase (Group 1
GII80_16500	ENOG4108KS4	Spore coat protein
GII80_16515	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GII80_16525	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GII80_16655	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
GII80_16660	ENOG4105VRR	gCN5-related N-acetyltransferase
GII80_16665	ENOG4105DZ6	Band 7 protein
GII80_16675	ENOG4106DF1	
GII80_16680	ENOG4108VNY	MOSC domain protein
GII80_16685	ENOG4108JB8	alcohol dehydrogenase
GII80_16690	ENOG4105C26	Dehydrogenase
GII80_16695	ENOG4105TRT	Transcriptional regulator
GII80_16710	ENOG4105CZN	Potassium uptake protein
GII80_16715	ENOG4107I77	yiaA/B two helix domain
GII80_16720	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GII80_16740	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GII80_16750	ENOG4105EE0	oxidoreductase
GII80_16755	ENOG4105DKG	l-rhamnose isomerase
GII80_16760	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
GII80_16765	ENOG4105DET	Rhamnulokinase
GII80_16770	ENOG4105E98	transcriptional regulator DeoR family
GII80_16780	ENOG4105C8Q	Methyl-accepting chemotaxis
GII80_16785	ENOG4105C8Q	Methyl-accepting chemotaxis
GII80_16790	ENOG4105C8Q	Methyl-accepting chemotaxis
GII80_16795	ENOG4105C8Q	Methyl-accepting chemotaxis
GII80_16810	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GII80_16825	ENOG4105C37	(CBS) domain
GII80_16840	ENOG4107PBV	potassium channel
GII80_16845	ENOG4107PBV	potassium channel
GII80_16860	ENOG4107QYV	phosphohexose isomerase
GII80_16870	ENOG4107QW4	alcohol dehydrogenase
GII80_16875	ENOG4105WG9	Conserved Protein
GII80_16885	ENOG4105CHM	Aminotransferase
GII80_16890	ENOG4108ZB6	transcriptional regulator AsnC family
GII80_16895	ENOG4108MUZ	hydrolase
GII80_16905	ENOG4105C87	Aminotransferase class I and II
GII80_16910	ENOG4108HGU	Histidine kinase
GII80_16915	ENOG4105Y38	Kinase-associated protein B
GII80_16935	ENOG4105BZ4	penicillin-binding protein
GII80_16940	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
GII80_16955	ENOG4108MRH	transcriptional regulatory protein
GII80_16960	ENOG4105DIH	basic membrane
GII80_16965	ENOG4108JQ9	ABC transporter
GII80_16970	ENOG4105UIB	(ABC) transporter
GII80_16990	ENOG4105D65	subunit l
GII80_16995	ENOG4105HC0	Na H antiporter
GII80_17000	ENOG4108ZE9	Monovalent cation H antiporter subunit C
GII80_17005	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GII80_17010	ENOG4105SC1	monovalent cation H antiporter subunit E
GII80_17020	ENOG4105KJM	monovalent cation h antiporter subunit g
GII80_17025	ENOG4105KA0	thioesterase Superfamily protein
GII80_17035	ENOG4105BZU	Histidine kinase
GII80_17065	ENOG4105D58	Diguanylate phosphodiesterase
GII80_17070	ENOG4105DAP	Nicotinate phosphoribosyltransferase
GII80_17095	ENOG4105C02	permease
GII80_17115	ENOG410904N	short-chain dehydrogenase reductase
GII80_17150	ENOG4108K8K	Transcriptional regulator
GII80_17155	ENOG4105DCF	alanine dehydrogenase
GII80_17165	ENOG4105WQT	MbtH domain protein
GII80_17170	ENOG4105CEY	Amp-dependent synthetase and ligase
GII80_17175	ENOG4105WQI	isochorismatase
GII80_17180	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
GII80_17185	ENOG4105E4F	Isochorismate synthase
GII80_17190	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
GII80_17195	ENOG4105NIV	Esterase
GII80_17215	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GII80_17225	ENOG41069ER	domain protein
GII80_17240	ENOG4105CEP	NADH dehydrogenase
GII80_17245	ENOG4105CAY	ferredoxin--nadp reductase
GII80_17265	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
GII80_17270	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GII80_17285	ENOG4105ZKE	UPF0349 protein
GII80_17300	ENOG41083MR	nifu domain-containing protein
GII80_17305	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GII80_17310	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GII80_17315	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
GII80_17320	ENOG4105D6E	homoserine dehydrogenase
GII80_17330	ENOG4108W5N	phosphatidylglycerophosphatase a
GII80_17335	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
GII80_17345	ENOG4105MMD	transcriptional regulator
GII80_17350	ENOG4106EGE	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GII80_17355	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GII80_17360	ENOG4105FAA	peptidase M23
GII80_17365	ENOG4108YTE	sporulation protein YunB
GII80_17370	ENOG4105KZD	Domain of unknown function (DUF1805)
GII80_17375	ENOG4107R8B	5'-nucleotidase
GII80_17385	ENOG4105I3N	Conserved Protein
GII80_17395	ENOG4105CD3	dihydroorotase
GII80_17400	ENOG4105G9B	Transcriptional regulator
GII80_17415	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
GII80_17420	ENOG4105VT2	5-hydroxyisourate hydrolase
GII80_17430	ENOG4107YV9	domain protein
GII80_17435	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
GII80_17450	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
GII80_17455	ENOG4105C5R	Aminotransferase
GII80_17470	ENOG4108K8S	endonuclease I
GII80_17475	ENOG4108IJ9	(ABC) transporter
GII80_17480	ENOG4105FDP	GntR family transcriptional regulator
GII80_17485	ENOG4108KPW	sugar kinase
GII80_17490	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GII80_17495	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GII80_17500	ENOG4105XN3	extracellular solute-binding protein family 1
GII80_17505	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
GII80_17510	ENOG4105PKS	Excinuclease abc c subunit domain protein
GII80_17515	ENOG4107VFR	oxidoreductase
GII80_17530	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
GII80_17535	ENOG4105NPE	arsR family transcriptional regulator
GII80_17540	ENOG4105DIW	FeS assembly protein SUFB
GII80_17545	ENOG4108UNV	SUF system FeS assembly protein, NifU family
GII80_17550	ENOG4105C9B	Cysteine desulfurase
GII80_17555	ENOG4105JRK	feS assembly protein SufD
GII80_17560	ENOG4105C3K	feS assembly ATPase SufC
GII80_17575	ENOG4105D01	(LipO)protein
GII80_17580	ENOG4108UMI	ABC transporter, permease
GII80_17585	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GII80_17610	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GII80_17615	ENOG41080E8	Transcriptional regulator, Spx MgsR family
GII80_17620	ENOG4105C1G	acyl-Coa dehydrogenase
GII80_17625	ENOG4105CHU	acetyl-coa acetyltransferase
GII80_17655	ENOG41067TZ	transcriptional regulator, MarR family
GII80_17660	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GII80_17665	ENOG4105MDS	4-oxalocrotonate tautomerase
GII80_17675	ENOG4105EGI	Transcriptional regulator
GII80_17685	ENOG4105E0A	ABC, transporter
GII80_17700	ENOG4105E1F	short-chain dehydrogenase reductase
GII80_17705	ENOG4105HUF	DNA protection during starvation protein
GII80_17710	ENOG4105C0H	protease
GII80_17720	ENOG4105F3H	Histidine kinase
GII80_17730	ENOG41067SE	Tetr family transcriptional regulator
GII80_17735	ENOG4105C9Q	fumarate hydratase class II
GII80_17760	ENOG4105WH1	Two component transcriptional regulator luxr family
GII80_17765	ENOG4105ENE	Histidine kinase
GII80_17780	ENOG41087YS	Phage shock protein A
GII80_17795	ENOG4108WBT	adenosyltransferase
GII80_17800	ENOG4105E0A	ABC, transporter
GII80_17805	ENOG4105EHG	Permease protein
GII80_17810	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GII80_17815	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
GII80_17820	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
GII80_17830	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GII80_17840	ENOG4106DF4	Sigma-70, region 4
GII80_17850	ENOG4105F0F	Oxalate decarboxylase
GII80_17860	ENOG4107RBB	ABC transporter, permease
GII80_17865	ENOG4105C19	ABC transporter
GII80_17870	ENOG4108WMK	Efflux transporter RND family MFP subunit
GII80_17875	ENOG4105E0A	ABC, transporter
GII80_17880	ENOG4105EHG	Permease protein
GII80_17885	ENOG4105DQ5	transport system permease protein
GII80_17895	ENOG4105D5Q	Arginine ornithine antiporter
GII80_17905	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
GII80_17910	ENOG4107QZ2	Sulfatase
GII80_17915	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
GII80_17920	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GII80_17925	ENOG4105E0C	molybdate abc transporter
GII80_17940	ENOG4105EEQ	Na H antiporter
GII80_17945	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GII80_17950	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GII80_17955	ENOG4105EEM	helicase
GII80_17960	ENOG4105EN6	Membrane
GII80_17970	ENOG4107ZQN	disulfide bond
GII80_17975	ENOG4105C59	p-type ATPase
GII80_17980	ENOG4105C59	p-type ATPase
GII80_17985	ENOG410681U	heavy metal transport detoxification protein
GII80_17990	ENOG4105VPX	protein, conserved in bacteria
GII80_17995	ENOG4105D9R	oxidoreductase
GII80_18000	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GII80_18005	ENOG4105ME7	Membrane
GII80_18010	ENOG4105RXJ	
GII80_18015	ENOG4105KPY	Small multidrug resistance protein
GII80_18020	ENOG4105KBX	Transcriptional regulator, TetR family
GII80_18025	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
GII80_18035	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GII80_18040	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GII80_18050	ENOG4105XZU	Preprotein translocase, subunit SecG
GII80_18075	ENOG4105KVH	Transcriptional regulator
GII80_18080	ENOG4105C8Q	Methyl-accepting chemotaxis
GII80_18085	ENOG4105R40	Glycine betaine carnitine choline
GII80_18090	ENOG4108HQR	Glycine betaine
GII80_18095	ENOG4105E90	ABC transporter
GII80_18100	ENOG4108IJ8	ABC transporter
GII80_18105	ENOG4107HG4	Transcriptional regulator
GII80_18115	ENOG4105H5S	
GII80_18130	ENOG41082BM	Transcriptional regulator, arsr family
GII80_18135	ENOG4105R40	Glycine betaine carnitine choline
GII80_18140	ENOG4108HQR	Glycine betaine
GII80_18145	ENOG4105E90	ABC transporter
GII80_18150	ENOG4108IJ8	ABC transporter
GII80_18155	ENOG4107HG4	Transcriptional regulator
GII80_18160	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GII80_18165	ENOG4108QCI	YvbH-like oligomerisation region
GII80_18175	ENOG4105T65	Membrane-associated protein
GII80_18180	ENOG4108W0I	acetyltransferase
GII80_18185	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GII80_18190	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GII80_18195	ENOG4105CP7	Triose-phosphate isomerase
GII80_18200	ENOG4105BZA	Phosphoglycerate kinase
GII80_18205	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GII80_18220	ENOG4105CMD	Transcriptional regulator, GntR family
GII80_18225	ENOG4105DEN	Luciferase family
GII80_18230	ENOG4105GZI	Transcriptional regulator
GII80_18235	ENOG4107RT3	EamA-like transporter family
GII80_18245	ENOG4105VRS	hydrolase family 18
GII80_18250	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GII80_18255	ENOG4107QR9	Iron-sulfur cluster binding protein
GII80_18260	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GII80_18270	ENOG4105BZU	Histidine kinase
GII80_18275	ENOG4105KCT	ABC transporter
GII80_18280	ENOG4108M15	ABC transporter
GII80_18285	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
GII80_18290	ENOG4108MJI	response regulator
GII80_18305	ENOG4105EG2	ABC transporter, permease
GII80_18315	ENOG4107FKK	extracellular solute-binding protein family 1
GII80_18325	ENOG4105JXH	GntR family transcriptional regulator
GII80_18330	ENOG4105DAA	L-lactate
GII80_18335	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GII80_18345	ENOG4108ZPC	Polysaccharide pyruvyl transferase
GII80_18350	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GII80_18355	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
GII80_18360	ENOG4105D3Q	Sugar transferase
GII80_18370	ENOG4105K64	Glycosyl transferase, family 2
GII80_18380	ENOG4107QRS	glycosyltransferase group 2 family protein
GII80_18385	ENOG41068W6	Capsular polysaccharide biosynthesis protein
GII80_18390	ENOG4108KMV	Glycosyl transferase (Group 1
GII80_18395	ENOG4105K64	Glycosyl transferase, family 2
GII80_18400	ENOG4108PQP	glycosyl transferase group 1
GII80_18410	ENOG4108QV3	biosynthesis protein
GII80_18415	ENOG4105HTX	biosynthesis protein
GII80_18425	ENOG4105EBR	Carboxylesterase
GII80_18435	ENOG4105PY6	Phenolic acid decarboxylase
GII80_18440	ENOG4105NI3	Protein of unknown function (DUF3237)
GII80_18450	ENOG4105FQP	Beta-lactamase
GII80_18455	ENOG4105EDQ	levansucrase EC 2.4.1.10
GII80_18460	ENOG4108HKT	sucrose-6-phosphate hydrolase
GII80_18465	ENOG4107QTZ	amino acid
GII80_18490	ENOG4105DNP	FAD linked oxidase domain protein
GII80_18495	ENOG4105IRW	patatin-like phospholipase family protein
GII80_18505	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GII80_18515	ENOG4105CG3	alpha amylase, catalytic region
GII80_18530	ENOG4105EG2	ABC transporter, permease
GII80_18535	ENOG4105D56	permease protein
GII80_18540	ENOG4107FKK	extracellular solute-binding protein family 1
GII80_18545	ENOG4108IUK	alpha amylase, catalytic
GII80_18550	ENOG4105FKQ	transcriptional regulator
GII80_18555	ENOG4108URH	decarboxylase
GII80_18560	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
GII80_18565	ENOG4105CHH	sulfate transporter
GII80_18570	ENOG4108V2W	Carbonate dehydratase
GII80_18575	ENOG4105C5I	Dehydrogenase
GII80_18585	ENOG4105C19	ABC transporter
GII80_18590	ENOG4105EWM	Histidine kinase
GII80_18600	ENOG4107A6P	
GII80_18605	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
GII80_18610	ENOG4105KRI	phosphocarrier protein (HPr
GII80_18615	ENOG4105CIE	May be required for sporulation (By similarity)
GII80_18620	ENOG4105CHW	UPF0052 protein
GII80_18625	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GII80_18630	ENOG4108Z4K	mutator MutT protein
GII80_18635	ENOG4105C3M	thioredoxin reductase
GII80_18650	ENOG4105BZ1	(ABC) transporter
GII80_18660	ENOG4106FGC	
GII80_18670	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GII80_18675	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GII80_18680	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GII80_18685	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GII80_18690	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GII80_18695	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GII80_18700	ENOG4107RN8	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GII80_18705	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
GII80_18715	ENOG4108E16	pectate lyase
GII80_18720	ENOG4108S4C	acetyltransferase
GII80_18725	ENOG4107XGZ	Hydrolase
GII80_18730	ENOG4105HKU	nucleoside recognition domain-containing protein
GII80_18735	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GII80_18740	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
GII80_18745	ENOG4105CE4	GlcNAc 6-P deacetylase
GII80_18750	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GII80_18755	ENOG4105FDP	GntR family transcriptional regulator
GII80_18760	ENOG41088CQ	domain protein
GII80_18770	ENOG4106A3M	Cytochrome p-450
GII80_18775	ENOG410625E	
GII80_18790	ENOG41086DT	Membrane protein of unknown function
GII80_18795	ENOG41067S9	phage shock protein C, PspC
GII80_18800	ENOG4108PY7	
GII80_18820	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GII80_18825	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GII80_18840	ENOG4105MKU	Transcriptional regulator
GII80_18860	ENOG4105CN1	protease
GII80_18865	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GII80_18870	ENOG4105CAK	Cell division ATP-binding protein ftsE
GII80_18895	ENOG4105MS2	ribosomal subunit Interface protein
GII80_18910	ENOG4105MQ3	flagellar protein FliS
GII80_18915	ENOG4107RT6	flagellar hook-associated
GII80_18920	ENOG41083S7	flagellar protein FlaG
GII80_18925	ENOG4105I03	Flagellin
GII80_18930	ENOG41085Y9	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GII80_18935	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
GII80_18940	ENOG4105MKD	
GII80_18945	ENOG4105DTJ	flagellar hook-associated protein
GII80_18950	ENOG4105E1Q	flagellar hook-associated protein
GII80_18965	ENOG4105RU3	
GII80_18970	ENOG41081UC	Inherit from COG: Competence protein
GII80_18990	ENOG4105WH1	Two component transcriptional regulator luxr family
GII80_18995	ENOG4105BZU	Histidine kinase
GII80_19000	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GII80_19005	ENOG4108KGH	TRANSCRIPTIONal
GII80_19010	ENOG4105ESV	Glycosyl transferase, family 4
GII80_19015	ENOG4107EF8	Glycosyl transferase (Group 1
GII80_19030	ENOG4105QZI	O-Antigen Polymerase
GII80_19035	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GII80_19040	ENOG4107RA4	Glycosyl transferase (Group 1
GII80_19045	ENOG4105PSV	Polysaccharide Biosynthesis Protein
GII80_19050	ENOG4105D3Q	Sugar transferase
GII80_19055	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GII80_19060	ENOG4105JFG	SpoIID LytB domain protein
GII80_19075	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GII80_19080	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GII80_19090	ENOG4107VDP	teichoic acid biosynthesis
GII80_19095	ENOG41088M2	Glycosyl transferase family 2
GII80_19105	ENOG4107SJB	teichoic acid biosynthesis
GII80_19115	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GII80_19120	ENOG4105EY8	ABC transporter
GII80_19130	ENOG4107SJB	teichoic acid biosynthesis
GII80_19135	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
GII80_19140	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
GII80_19150	ENOG4107RZX	Teichoic acid biosynthesis protein
GII80_19155	ENOG410651K	Teichoic acid biosynthesis protein C
GII80_19165	ENOG4105DG6	mannose-6-phosphate isomerase
GII80_19180	ENOG4108NHD	germination protein
GII80_19185	ENOG4105C54	Major Facilitator superfamily
GII80_19190	ENOG4108KGH	TRANSCRIPTIONal
GII80_19195	ENOG4105J7I	hydrolase
GII80_19200	ENOG4105K4H	Nlp p60 protein
GII80_19210	ENOG4105PNM	synthesis protein
GII80_19220	ENOG4105N98	Capsule biosynthesis protein capB
GII80_19225	ENOG4105ETE	Transcriptional regulator (LacI family
GII80_19230	ENOG4108RVA	ribokinase
GII80_19235	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GII80_19240	ENOG4105C2J	ABC transporter
GII80_19245	ENOG4105CNN	ABC, transporter
GII80_19250	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GII80_19265	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GII80_19270	ENOG4107FQX	Alpha-acetolactate decarboxylase
GII80_19280	ENOG4107RSM	transcriptional regulator
GII80_19295	ENOG4106UIA	
GII80_19310	ENOG4107XC4	flavin reductase domain protein, FMN-binding
GII80_19320	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GII80_19330	ENOG4105CAH	Chromate
GII80_19335	ENOG4105FGV	Chromate
GII80_19345	ENOG4108WS4	fmn reductase
GII80_19350	ENOG4107V2S	Transcriptional regulator
GII80_19355	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
GII80_19360	ENOG4106YAD	MORN repeat variant
GII80_19385	ENOG4108XI2	Domain of unknown function (DUF1963)
GII80_19390	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GII80_19395	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
GII80_19400	ENOG4107YJ4	chain length determinant protein
GII80_19405	ENOG4105HTX	biosynthesis protein
GII80_19415	ENOG4105KBK	Zinc finger, swim domain protein
GII80_19420	ENOG4105C0D	helicase
GII80_19425	ENOG410667J	hydrolase
GII80_19430	ENOG4105E98	transcriptional regulator DeoR family
GII80_19435	ENOG4105Z8H	single-stranded DNA-binding protein
GII80_19465	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GII80_19470	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GII80_19480	ENOG4105CGA	flagellar basal-body rod protein FlgG
GII80_19490	ENOG4105DFF	Rod shape-determining protein mreb
GII80_19495	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
GII80_19505	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
GII80_19510	ENOG4105CZM	Major Facilitator
GII80_19515	ENOG4108M26	parallel beta-helix repeat protein
GII80_19520	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
GII80_19525	ENOG41080V3	Major Facilitator superfamily
GII80_19530	ENOG4105D3W	isochorismatase
GII80_19535	ENOG4107P26	
GII80_19540	ENOG4105BZU	Histidine kinase
GII80_19550	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
GII80_19560	ENOG4105FRN	stage II sporulation protein
GII80_19565	ENOG4107TCE	N-acetyltransferase
GII80_19585	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GII80_19590	ENOG4107TXC	Transcriptional regulator
GII80_19595	ENOG4106BRK	
GII80_19600	ENOG4108RYK	Nad-dependent epimerase dehydratase
GII80_19605	ENOG4108Z40	Transcriptional regulator
GII80_19610	ENOG4105CQM	Urea amidohydrolase subunit alpha
GII80_19615	ENOG4105KI2	Urea amidohydrolase subunit beta
GII80_19620	ENOG4108YZ9	Urea amidohydrolase subunit gamma
GII80_19655	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GII80_19665	ENOG4108TF4	von Willebrand factor, type A
GII80_19680	ENOG4105JFG	SpoIID LytB domain protein
GII80_19685	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GII80_19695	ENOG4106778	Protein of unknown function (DUF1146)
GII80_19705	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GII80_19710	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GII80_19715	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GII80_19720	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GII80_19740	ENOG4107RB6	it plays a direct role in the translocation of protons across the membrane (By similarity)
GII80_19750	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GII80_19755	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GII80_19760	ENOG4108UIC	UPF0340 protein
GII80_19765	ENOG4108YZG	isomerase
GII80_19770	ENOG4107WAU	Protein tyrosine phosphatase
GII80_19775	ENOG410815N	Probably functions as a manganese efflux pump (By similarity)
GII80_19780	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GII80_19790	ENOG4108ZXQ	stage ii sporulation protein r
GII80_19805	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GII80_19810	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GII80_19815	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GII80_19825	ENOG4107TT2	Auxin Efflux Carrier
GII80_19830	ENOG4105C6K	Malic enzyme
GII80_19835	ENOG4107104	thymidine kinase
GII80_19840	ENOG41082DI	50s ribosomal protein l31
GII80_19845	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GII80_19855	ENOG4105CBT	Fructose-1,6-bisphosphatase
GII80_19860	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GII80_19865	ENOG4107XMI	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII80_19870	ENOG4105D2N	Aldolase
GII80_19875	ENOG410812K	response regulator receiver protein
GII80_19885	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GII80_19895	ENOG4105C1G	acyl-Coa dehydrogenase
GII80_19900	ENOG4105DF6	Fe-S oxidoreductase
GII80_19910	ENOG4105E5J	UV damage endonuclease
GII80_19920	ENOG4105NAE	bifunctional deaminase-reductase domain protein
GII80_19950	ENOG4107V6Q	Cyclic nucleotide-binding domain
GII80_19960	ENOG4105C75	arginyL-tRNA synthetase
GII80_19965	ENOG410684U	Domain of unknown function (DUF1934)
GII80_19980	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
GII80_20030	ENOG4107JM4	Tetratricopeptide repeat
GII80_20040	ENOG4108UIN	ybak prolyl-trna synthetase associated region
GII80_20045	ENOG4105CYW	agmatinase
GII80_20050	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
GII80_20055	ENOG4105BZ4	penicillin-binding protein
GII80_20060	ENOG4108XFG	YwhD family
GII80_20065	ENOG4108Z4T	Peptidase M50
GII80_20070	ENOG41069HH	4-oxalocrotonate tautomerase
GII80_20075	ENOG41067TZ	transcriptional regulator, MarR family
GII80_20080	ENOG4105C22	threonyL-tRNA synthetase
GII80_20085	ENOG4105C57	major facilitator superfamily
GII80_20090	ENOG41062ES	Transcriptional regulator
GII80_20100	ENOG4105DCI	Phosphohydrolase
GII80_20110	ENOG4108VCI	transcription factor, rsfa family
GII80_20115	ENOG4108RNG	Permease of the drug metabolite transporter
GII80_20120	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
GII80_20125	ENOG4105DUM	transcriptional regulator, lysR family
GII80_20130	ENOG4108IJ2	phosphate acetyltransferase
GII80_20145	ENOG4105CHM	Aminotransferase
GII80_20155	ENOG4108V3M	Inherit from COG: acetyl-CoA carboxylase biotin carboxylase
GII80_20160	ENOG4105CHR	reductase
GII80_20165	ENOG4106CHD	Bacilysin biosynthesis protein bacB
GII80_20170	ENOG41061WN	bacilysin biosynthesis protein
GII80_20175	ENOG4105FCW	Major Facilitator superfamily
GII80_20190	ENOG4105C26	Dehydrogenase
GII80_20195	ENOG4105D82	Glutamate dehydrogenase
GII80_20205	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
GII80_20210	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
GII80_20215	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GII80_20220	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GII80_20225	ENOG4107P9E	Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG
GII80_20230	ENOG4107TY6	Acylneuraminate cytidylyltransferase
GII80_20240	ENOG41067MN	Spore coat polysaccharide biosynthesis protein spsD
GII80_20245	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GII80_20280	ENOG4105C26	Dehydrogenase
GII80_20285	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GII80_20290	ENOG4108RJ9	Glycosyl transferase, family 2
GII80_20310	ENOG4105DWF	phosphomethylpyrimidine kinase
GII80_20325	ENOG4105C5Y	PTS System
GII80_20330	ENOG4108QTI	)-transporter
GII80_20345	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
GII80_20350	ENOG4105DEN	Luciferase family
GII80_20355	ENOG4108DBC	nitroreductase
GII80_20370	ENOG41060D1	Quinol oxidase
GII80_20375	ENOG4105CCU	oxidase (Subunit III)
GII80_20380	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GII80_20385	ENOG4105E2S	oxidase) subunit II
GII80_20390	ENOG4107BMA	Transglycosylase associated protein
GII80_20400	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GII80_20405	ENOG4105WH5	Teichoic acid glycosylation protein
GII80_20430	ENOG4107ZXU	DSBA oxidoreductase
GII80_20435	ENOG4105DBE	peroxidase
GII80_20440	ENOG410650H	(LipO)protein
GII80_20445	ENOG4107SJW	iron permease, FTR1
GII80_20450	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GII80_20460	ENOG4105CMU	LysR family (Transcriptional regulator
GII80_20465	ENOG4105VAW	lrga family
GII80_20470	ENOG41067MG	lrgb family
GII80_20475	ENOG4105D8G	Major Facilitator superfamily
GII80_20485	ENOG4105DR4	Methyltransferase
GII80_20495	ENOG4108YV3	Protein of unknown function (DUF2711)
GII80_20500	ENOG4105CK1	PTS System
GII80_20505	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
GII80_20520	ENOG4105X1N	Glycosyl transferase family 8
GII80_20530	ENOG4105GVJ	transcriptional regulator
GII80_20535	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GII80_20540	ENOG4105IIU	Aminopeptidase
GII80_20550	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GII80_20565	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
GII80_20570	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GII80_20580	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
GII80_20585	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
GII80_20590	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GII80_20595	ENOG4105F8D	glycoside hydrolase family 4
GII80_20600	ENOG4105VCP	PTS System
GII80_20605	ENOG4105CK1	PTS System
GII80_20610	ENOG4105VZJ	PTS System
GII80_20615	ENOG4105EMD	TRANSCRIPTIONal
GII80_20625	ENOG4108VX5	3-methyladenine DNA glycosylase
GII80_20630	ENOG4105CH6	catalase
GII80_20645	ENOG4105DA5	(ABC) transporter
GII80_20650	ENOG41069JR	
GII80_20670	ENOG4105ETS	cytosine purines uracil thiamine allantoin
GII80_20675	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GII80_20680	ENOG4108JJ8	(ABC) transporter
GII80_20685	ENOG4108JJ9	ABC, transporter
GII80_20690	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GII80_20695	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GII80_20700	ENOG4105D2K	citrate carrier protein
GII80_20715	ENOG4107BJW	polysaccharide deacetylase
GII80_20735	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
GII80_20745	ENOG4105CMR	udp-glucose 4-epimerase
GII80_20750	ENOG4105KIS	phospholipid-binding protein
GII80_20755	ENOG4108WAV	Transcriptional regulator
GII80_20765	ENOG4105BZU	Histidine kinase
GII80_20770	ENOG4105WH1	Two component transcriptional regulator luxr family
GII80_20775	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GII80_20800	ENOG4105DTD	Dehydrogenase
GII80_20805	ENOG4108IIH	CoA-transferase subunit B
GII80_20810	ENOG4105D6N	CoA-transferase, subunit a
GII80_20815	ENOG4105CY2	Citrate transporter
GII80_20820	ENOG4105DHI	Methyltransferase
GII80_20840	ENOG4105CH6	catalase
GII80_20845	ENOG4105D4T	Citrate transporter
GII80_20850	ENOG4108RZ2	Glycoside hydrolase family 16
GII80_20855	ENOG4105CID	antiterminator
GII80_20865	ENOG4105DEU	major facilitator superfamily
GII80_20870	ENOG4105C1J	atp-dependent rna helicase
GII80_20875	ENOG4107TDE	lipolytic protein G-D-S-L family
GII80_20935	ENOG4105CNA	YD repeat protein
GII80_20945	ENOG4107YZX	Universal stress protein
GII80_20950	ENOG4105CS2	ec 3.2.1.21
GII80_20955	ENOG4105C5Y	PTS System
GII80_20970	ENOG4107EV6	Inherit from COG: YD repeat protein
GII80_20985	ENOG4106Z5D	Glycoside Hydrolase Family 43
GII80_21000	ENOG4105C84	Histidine ammonia-lyase
GII80_21005	ENOG4105CGP	Urocanate hydratase
GII80_21010	ENOG4105CI2	imidazolone-5-propionate hydrolase
GII80_21015	ENOG4107W25	arginase agmatinase formiminoglutamase
GII80_21025	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GII80_21030	ENOG4105D9N	nucleoside
GII80_21040	ENOG4107RHR	regulatoR
GII80_21045	ENOG4108TM9	integral membrane protein
GII80_21050	ENOG4105ENY	Ethanolamine utilization protein eutH
GII80_21055	ENOG4108PGP	mmge prpd family protein
GII80_21060	ENOG4105CH2	amidohydrolase
GII80_21070	ENOG4108HW4	amino acid AbC transporter
GII80_21075	ENOG4105EAB	amino acid AbC transporter
GII80_21080	ENOG4108XSB	acetyltransferase, (GNAT) family
GII80_21085	ENOG4105CPU	Monooxygenase
GII80_21095	ENOG4107QHE	Choloylglycine hydrolase
GII80_21100	ENOG410667J	hydrolase
GII80_21130	ENOG4108V5C	ABC transporter
GII80_21160	ENOG4105D2N	Aldolase
GII80_21165	ENOG4107TRN	Xylose isomerase domain protein TIM barrel
GII80_21170	ENOG4105F0H	myo-inositol catabolism protein
GII80_21175	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
GII80_21185	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
GII80_21190	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
GII80_21195	ENOG4105D7K	pfkb domain protein
GII80_21200	ENOG4105DH8	myo-inositol catabolism
GII80_21205	ENOG4105C26	Dehydrogenase
GII80_21215	ENOG4105CPC	Aldo Keto reductase
GII80_21230	ENOG4107QNK	)-transporter
GII80_21235	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GII80_21245	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GII80_21250	ENOG4105ST3	Transcriptional regulator
GII80_21255	ENOG4105C26	Dehydrogenase
GII80_21260	ENOG4108YM7	Gcn5-related n-acetyltransferase
GII80_21265	ENOG4105N1N	Cupin superfamily protein
GII80_21270	ENOG4107Y1Y	Methyltransferase
GII80_21285	ENOG4105CAQ	asparagine synthetase
GII80_21290	ENOG4105F22	Major Facilitator Superfamily
GII80_21295	ENOG4108ITS	PQQ enzyme repeat
GII80_21305	ENOG41085PJ	rdd domain containing protein
GII80_21320	ENOG4105J7D	transcriptional regulator
GII80_21325	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
GII80_21330	ENOG41061AU	MarR family Transcriptional regulator
GII80_21340	ENOG41067MG	lrgb family
GII80_21350	ENOG4105BZW	Glycerate kinase
GII80_21355	ENOG4105G3Z	GntR family transcriptional regulator
GII80_21360	ENOG4105CMG	Carbohydrate kinase
GII80_21365	ENOG4105C6Z	Gluconate
GII80_21370	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GII80_21375	ENOG4105D3R	alkyl hydroperoxide reductase
GII80_21380	ENOG4108JU3	Alkyl hydroperoxide reductase
GII80_21385	ENOG4105CS2	ec 3.2.1.21
GII80_21395	ENOG4105C5Y	PTS System
GII80_21400	ENOG4108S3Y	transcriptional regulator
GII80_21410	ENOG4106KKU	
GII80_21415	ENOG4108Z15	abc transporter atp-binding protein
GII80_21425	ENOG4105Y2Z	radical SAM domain protein
GII80_21435	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
GII80_21450	ENOG41069I7	
GII80_21455	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GII80_21470	ENOG4105E2A	Dehydrogenase
GII80_21490	ENOG4105NUN	Orthopoxvirus protein of unknown function (DUF830)
GII80_21495	ENOG4105WQG	acetyltransferase
GII80_21500	ENOG410780I	phosphoprotein phosphatase activity
GII80_21510	ENOG41066UZ	arginase EC 3.5.3.1
GII80_21515	ENOG4108IQI	permease
GII80_21520	ENOG4105C8Y	Acetylornithine aminotransferase
GII80_21525	ENOG4108JUB	Transcriptional regulator
GII80_21540	ENOG4105C0H	protease
GII80_21545	ENOG4105Q2H	domain protein
GII80_21560	ENOG4105BZU	Histidine kinase
GII80_21565	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GII80_21590	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GII80_21595	ENOG4105HB7	Glyoxalase Bleomycin resistance protein (Dioxygenase
GII80_21600	ENOG4105CDU	Replicative dna helicase
GII80_21620	ENOG4105DJ2	Major Facilitator Superfamily
GII80_21625	ENOG4105EDW	glycosyl transferase, family 39
GII80_21630	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GII80_21635	ENOG4105BZR	domain protein
GII80_21640	ENOG4108XMW	Membrane
GII80_21655	ENOG4105KVH	Transcriptional regulator
GII80_21660	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GII80_21690	ENOG41060CM	Protein of unknown function (DUF2712)
GII80_21695	ENOG4106NWU	
GII80_21700	ENOG41064J9	
GII80_21705	ENOG41064SH	Protein of unknown function (DUF2705)
GII80_21710	ENOG4108RDQ	ABC transporter
GII80_21725	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
GII80_21730	ENOG4105DDN	Pentapeptide repeat-containing protein
GII80_21735	ENOG4105D94	Major Facilitator Superfamily
GII80_21740	ENOG4107RSM	transcriptional regulator
GII80_21745	ENOG41082BV	acetyltransferase
GII80_21750	ENOG41081I9	integral membrane protein
GII80_21760	ENOG4108U05	Transcriptional regulator
GII80_21765	ENOG41082BV	acetyltransferase
GII80_21775	ENOG4108U7W	acetyltransferase
GII80_21780	ENOG4105UNS	Pfam:DUF419
GII80_21785	ENOG4105NAE	bifunctional deaminase-reductase domain protein
GII80_21795	ENOG4108J8C	transporter major facilitator family protein
GII80_21815	ENOG4108IPJ	Membrane
GII80_21820	ENOG4105C7Z	Conserved Protein
GII80_21825	ENOG4107FCW	Abortive infection protein
GII80_21835	ENOG4108UW5	maltose o-acetyltransferase
GII80_21840	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
GII80_21850	ENOG4105CGK	Exodeoxyribonuclease III
GII80_21855	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GII80_21860	ENOG4108UUM	single-stranded DNA-binding protein
GII80_21865	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GII80_21870	ENOG4105C3G	gtp-binding protein
GII80_21875	ENOG4108J2R	molybdopterin oxidoreductase
GII80_21880	ENOG4105VDK	protein, conserved in bacteria
GII80_21890	ENOG4108ZDA	Sporulation protein YyaC
GII80_21895	ENOG4105FA0	parb-like partition protein
GII80_21900	ENOG4107QJE	Chromosome Partitioning Protein
GII80_21915	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GII80_21920	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GII80_21925	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GII80_21940	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GII80_21985	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GII80_21990	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GII80_22110	ENOG4108FKH	Transglycosylase SLT domain
GII80_22215	ENOG41069ER	domain protein
GII80_22295	ENOG41088HM	
GII80_22300	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GII80_22305	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GII80_22310	ENOG4105NQC	Flavodoxin
GII80_22385	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GII80_22400	ENOG4106J9J	DNA polymerase
GII80_22420	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)