locus-tag	class	description
GII80_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII80_00010	COG0592	DNA-directed DNA polymerase activity
GII80_00015	COG2501	S4 domain
GII80_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII80_00030	COG0187	DNA topoisomerase II activity
GII80_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII80_00070	COG0516	GMP reductase activity
GII80_00070	COG0517	IMP dehydrogenase activity
GII80_00075	COG1686	Belongs to the peptidase S11 family
GII80_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII80_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII80_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII80_00100	COG1428	Deoxynucleoside kinase
GII80_00105	COG1428	Deoxynucleoside kinase
GII80_00110	COG1388	LysM domain
GII80_00110	COG3858	chitin binding
GII80_00115	COG1335	isochorismatase
GII80_00120	COG0590	tRNA wobble adenosine to inosine editing
GII80_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII80_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII80_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII80_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII80_00190	COG3853	Toxic anion resistance protein (TelA)
GII80_00195	COG1982	Orn Lys Arg decarboxylase major
GII80_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII80_00205	COG3870	Protein conserved in bacteria
GII80_00210	COG1728	Protein conserved in bacteria
GII80_00215	COG0470	DNA polymerase III
GII80_00220	COG1774	PSP1 C-terminal conserved region
GII80_00225	COG4467	Involved in initiation control of chromosome replication
GII80_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII80_00235	COG2827	Endonuclease containing a URI domain
GII80_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII80_00245	COG2002	toxin-antitoxin pair type II binding
GII80_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII80_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII80_00255	COG0084	hydrolase, TatD family'
GII80_00260	COG3584	3D domain protein
GII80_00260	COG3583	domain protein
GII80_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII80_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII80_00280	COG4466	Protein conserved in bacteria
GII80_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII80_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII80_00300	COG0251	oxidation-reduction process
GII80_00305	COG2088	sporulation resulting in formation of a cellular spore
GII80_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII80_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII80_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII80_00325	COG0193	aminoacyl-tRNA hydrolase activity
GII80_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII80_00340	COG2002	toxin-antitoxin pair type II binding
GII80_00345	COG2244	polysaccharide biosynthetic process
GII80_00350	COG3956	TIGRFAM MazG family protein
GII80_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII80_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII80_00375	COG1098	S1 RNA binding domain
GII80_00390	COG2208	phosphoserine phosphatase activity
GII80_00395	COG2304	oxidoreductase activity
GII80_00400	COG0515	serine threonine protein kinase
GII80_00405	COG0037	tRNA processing
GII80_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII80_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII80_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII80_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII80_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII80_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII80_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII80_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII80_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII80_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII80_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII80_00470	COG1396	sequence-specific DNA binding
GII80_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII80_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII80_00560	COG4463	regulation of RNA biosynthetic process
GII80_00565	COG3880	PFAM UvrB UvrC protein
GII80_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII80_00575	COG0542	response to heat
GII80_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII80_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII80_00590	COG4956	integral membrane protein (PIN domain superfamily)
GII80_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII80_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII80_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII80_00610	COG1045	serine acetyltransferase
GII80_00615	COG0215	cysteine-tRNA ligase activity
GII80_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII80_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII80_00630	COG3688	RNA-binding protein containing a PIN domain
GII80_00635	COG1595	DNA-templated transcription, initiation
GII80_00640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII80_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII80_00650	COG0250	Participates in transcription elongation, termination and antitermination
GII80_00655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GII80_00660	COG0081	regulation of translation
GII80_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII80_00670	COG0222	ribosome binding
GII80_00675	COG2813	Specifically methylates the guanine in position
GII80_00680	COG0085	RNA polymerase activity
GII80_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII80_00690	COG1358	cellular component organization or biogenesis
GII80_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII80_00700	COG0049	tRNA binding
GII80_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII80_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII80_00715	COG0596	Alpha beta hydrolase
GII80_00720	COG0051	transcription antitermination factor activity, RNA binding
GII80_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII80_00730	COG0088	Forms part of the polypeptide exit tunnel
GII80_00735	COG0089	rRNA binding
GII80_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII80_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GII80_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GII80_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GII80_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII80_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
GII80_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII80_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII80_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII80_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII80_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII80_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII80_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII80_00815	COG1841	ribosomal large subunit assembly
GII80_00820	COG0200	Binds to the 23S rRNA
GII80_00825	COG0201	protein transport
GII80_00830	COG0563	adenylate kinase activity
GII80_00835	COG0024	Methionine aminopeptidase
GII80_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII80_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GII80_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII80_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII80_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII80_00865	COG0202	RNA polymerase activity
GII80_00870	COG0203	ribosomal protein L17
GII80_00875	COG1122	ATPase activity
GII80_00880	COG1122	ATPase activity
GII80_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII80_00890	COG0101	tRNA pseudouridine synthase activity
GII80_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII80_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII80_00905	COG2226	methyltransferase
GII80_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII80_00920	COG0489	protein tyrosine kinase activity
GII80_00930	COG2194	sulfuric ester hydrolase activity
GII80_00935	COG0726	polysaccharide deacetylase
GII80_01020	COG0659	secondary active sulfate transmembrane transporter activity
GII80_01025	COG0385	Bile acid
GII80_01030	COG2819	hydrolase of the alpha beta superfamily
GII80_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII80_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII80_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII80_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII80_01050	COG2207	Transcriptional regulator
GII80_01055	COG3876	Protein conserved in bacteria
GII80_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
GII80_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII80_01070	COG1263	PTS System
GII80_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_01075	COG1737	Transcriptional regulator
GII80_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII80_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII80_01090	COG1683	Conserved Protein
GII80_01120	COG1595	DNA-templated transcription, initiation
GII80_01125	COG5662	AntiSigma factor
GII80_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII80_01135	COG4856	YbbR-like protein
GII80_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII80_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII80_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII80_01160	COG2169	Transcriptional regulator
GII80_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII80_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII80_01175	COG3002	Belongs to the UPF0753 family
GII80_01180	COG0288	reversible hydration of carbon dioxide
GII80_01190	COG5609	conserved protein (DUF2294)
GII80_01195	COG0640	Transcriptional regulator
GII80_01200	COG2814	Major facilitator Superfamily
GII80_01205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII80_01215	COG0535	radical SAM domain protein
GII80_01220	COG1266	CAAX protease self-immunity
GII80_01225	COG1131	(ABC) transporter
GII80_01235	COG1413	lyase activity
GII80_01240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_01245	COG0596	Alpha beta hydrolase
GII80_01250	COG0745	RESPONSE REGULATOR receiver
GII80_01255	COG0642	Histidine kinase
GII80_01265	COG0515	serine threonine protein kinase
GII80_01280	COG1113	amino acid transport
GII80_01295	COG2602	Beta-lactamase
GII80_01300	COG2124	cytochrome p450
GII80_01310	COG0531	amino acid
GII80_01315	COG0584	glycerophosphoryl diester phosphodiesterase
GII80_01320	COG2271	Major facilitator Superfamily
GII80_01330	COG0456	acetyltransferase
GII80_01330	COG1846	Transcriptional regulator
GII80_01335	COG2271	Major facilitator Superfamily
GII80_01350	COG3409	Peptidoglycan-binding domain 1 protein
GII80_01355	COG0697	spore germination
GII80_01360	COG1917	Cupin 2, conserved barrel domain protein
GII80_01360	COG2207	Transcriptional regulator
GII80_01365	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII80_01370	COG3591	Belongs to the peptidase S1B family
GII80_01380	COG0596	Alpha beta hydrolase
GII80_01385	COG1183	phosphatidylcholine synthase activity
GII80_01390	COG0586	Pfam SNARE associated Golgi protein
GII80_01395	COG0688	phosphatidylethanolamine metabolic process
GII80_01405	COG2312	Erythromycin esterase
GII80_01410	COG2207	Transcriptional regulator
GII80_01420	COG1301	dicarboxylic acid transport
GII80_01425	COG1263	PTS System
GII80_01425	COG2190	(PTS) system
GII80_01425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_01430	COG0363	glucosamine-6-phosphate deaminase activity
GII80_01445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII80_01450	COG0833	amino acid
GII80_01455	COG2040	homocysteine
GII80_01465	COG1115	amino acid carrier protein
GII80_01470	COG2066	Belongs to the glutaminase family
GII80_01475	COG4191	Histidine kinase
GII80_01480	COG0784	Response regulator, receiver
GII80_01485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII80_01490	COG1012	belongs to the aldehyde dehydrogenase family
GII80_01495	COG2271	Major facilitator Superfamily
GII80_01500	COG4948	Mandelate Racemase Muconate Lactonizing
GII80_01505	COG2186	Transcriptional regulator
GII80_01510	COG2721	sulfolactate sulfo-lyase activity
GII80_01515	COG3173	Aminoglycoside phosphotransferase
GII80_01525	COG0697	spore germination
GII80_01530	COG0745	RESPONSE REGULATOR receiver
GII80_01535	COG2205	protein histidine kinase activity
GII80_01540	COG1131	(ABC) transporter
GII80_01560	COG3773	Cell wall hydrolase
GII80_01565	COG2304	oxidoreductase activity
GII80_01575	COG3540	Alkaline phosphatase
GII80_01580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII80_01585	COG0805	protein transport
GII80_01590	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII80_01595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII80_01600	COG0477	Major facilitator Superfamily
GII80_01605	COG1309	transcriptional regulator
GII80_01610	COG0252	asparaginase activity
GII80_01615	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII80_01620	COG1714	RDD family
GII80_01625	COG1405	negative regulation of cell septum assembly
GII80_01625	COG3012	SEC-C Motif Domain Protein
GII80_01630	COG3290	protein histidine kinase activity
GII80_01635	COG3279	Response regulator of the LytR AlgR family
GII80_01640	COG4555	ABC transporter
GII80_01645	COG1668	transmembrane transport
GII80_01650	COG0667	Aldo Keto reductase
GII80_01665	COG1595	DNA-templated transcription, initiation
GII80_01670	COG1595	DNA-templated transcription, initiation
GII80_01675	COG1876	peptidase activity
GII80_01680	COG0457	Tetratricopeptide repeat
GII80_01685	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_01690	COG0366	Alpha amylase catalytic
GII80_01695	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII80_01700	COG1121	(ABC) transporter
GII80_01705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII80_01710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII80_01715	COG2310	stress, protein
GII80_01720	COG2310	stress, protein
GII80_01725	COG2310	stress, protein
GII80_01730	COG0861	Integral membrane protein TerC family
GII80_01740	COG3853	Toxic anion resistance protein (TelA)
GII80_01745	COG0477	Major facilitator Superfamily
GII80_01750	COG2814	Major facilitator Superfamily
GII80_01755	COG0640	Transcriptional regulator
GII80_01760	COG4175	Glycine betaine
GII80_01760	COG0517	IMP dehydrogenase activity
GII80_01765	COG4176	ABC-type proline glycine betaine transport system permease component
GII80_01770	COG2113	Glycine betaine
GII80_01775	COG1473	amidohydrolase
GII80_01780	COG1288	antiporter activity
GII80_01790	COG0366	Alpha amylase catalytic
GII80_01795	COG0039	L-malate dehydrogenase activity
GII80_01800	COG1620	l-lactate permease
GII80_01805	COG2814	Major facilitator Superfamily
GII80_01810	COG1846	Transcriptional regulator
GII80_01815	COG1280	lysine exporter protein (LysE YggA)
GII80_01820	COG3403	YqcI/YcgG family
GII80_01825	COG1113	amino acid transport
GII80_01830	COG3665	Urea carboxylase-associated protein
GII80_01835	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII80_01840	COG1660	Displays ATPase and GTPase activities
GII80_01845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII80_01850	COG2226	methyltransferase
GII80_01855	COG0583	DNA-binding transcription factor activity
GII80_01860	COG3458	cephalosporin-C deacetylase activity
GII80_01865	COG3541	Predicted nucleotidyltransferase
GII80_01870	COG0506	proline dehydrogenase activity
GII80_01875	COG1012	belongs to the aldehyde dehydrogenase family
GII80_01880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII80_01885	COG2508	Transcriptional regulator
GII80_01890	COG3689	TIGRFAM TIGR03943 family protein
GII80_01895	COG0701	Predicted permease
GII80_01900	COG2267	carboxylic ester hydrolase activity
GII80_01905	COG0492	ferredoxin-NADP+ reductase activity
GII80_01910	COG1587	Uroporphyrinogen-III synthase
GII80_01910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII80_01915	COG2146	nitrite reductase [NAD(P)H] activity
GII80_01920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII80_01925	COG0243	molybdopterin cofactor binding
GII80_01930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII80_01935	COG2223	nitrite transmembrane transporter activity
GII80_01940	COG1469	GTP cyclohydrolase I activity
GII80_01945	COG1376	ErfK ybiS ycfS ynhG family protein
GII80_01955	COG0523	cobalamin synthesis protein
GII80_01960	COG0765	amino acid transport
GII80_01965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII80_01975	COG1714	RDD family
GII80_01985	COG2723	6-phospho-beta-galactosidase activity
GII80_01995	COG3209	COG3209 Rhs family protein
GII80_02000	COG0840	transmembrane signaling receptor activity
GII80_02000	COG3290	protein histidine kinase activity
GII80_02005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII80_02010	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII80_02015	COG1733	regulation of RNA biosynthetic process
GII80_02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_02035	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII80_02040	COG2814	Major facilitator Superfamily
GII80_02050	COG0697	spore germination
GII80_02055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII80_02065	COG2364	Membrane
GII80_02070	COG1126	abc transporter atp-binding protein
GII80_02075	COG0765	amino acid transport
GII80_02080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII80_02085	COG0583	DNA-binding transcription factor activity
GII80_02090	COG0163	prenyltransferase activity
GII80_02095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII80_02110	COG0596	Alpha beta hydrolase
GII80_02115	COG3104	oligopeptide transport
GII80_02120	COG5434	Belongs to the glycosyl hydrolase 28 family
GII80_02130	COG0697	spore germination
GII80_02140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII80_02145	COG1136	(ABC) transporter
GII80_02150	COG0577	efflux transmembrane transporter activity
GII80_02155	COG0745	RESPONSE REGULATOR receiver
GII80_02160	COG3850	Histidine kinase
GII80_02160	COG5002	protein histidine kinase activity
GII80_02165	COG0457	Tetratricopeptide repeat
GII80_02185	COG0527	aspartate kinase activity
GII80_02190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII80_02195	COG4605	iron ion homeostasis
GII80_02200	COG4604	ABC transporter, ATP-binding protein
GII80_02205	COG4607	ABC-type enterochelin transport system periplasmic component
GII80_02210	COG2814	Major facilitator Superfamily
GII80_02215	COG1309	transcriptional regulator
GII80_02220	COG0778	Nitroreductase
GII80_02225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII80_02230	COG0640	Transcriptional regulator
GII80_02235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII80_02240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII80_02245	COG1012	belongs to the aldehyde dehydrogenase family
GII80_02250	COG4975	Glucose uptake
GII80_02255	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_02260	COG4549	nuclear export factor GLE1
GII80_02265	COG1276	copper resistance
GII80_02265	COG2372	response to copper ion
GII80_02270	COG1349	DNA-binding transcription factor activity
GII80_02280	COG2213	PTS system mannitol-specific
GII80_02285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII80_02290	COG0246	Mannitol dehydrogenase
GII80_02295	COG0473	3-isopropylmalate dehydrogenase activity
GII80_02300	COG0681	Belongs to the peptidase S26 family
GII80_02305	COG0412	Dienelactone hydrolase
GII80_02310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII80_02320	COG0561	phosphatase activity
GII80_02325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII80_02330	COG1914	H( )-stimulated, divalent metal cation uptake system
GII80_02335	COG4336	lyase activity
GII80_02340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII80_02345	COG1984	allophanate hydrolase subunit 2
GII80_02350	COG1414	Transcriptional regulator
GII80_02355	COG2755	lipolytic protein G-D-S-L family
GII80_02365	COG2329	Antibiotic biosynthesis monooxygenase
GII80_02370	COG0768	penicillin binding
GII80_02375	COG4989	oxidoreductase activity
GII80_02380	COG3711	transcriptional antiterminator
GII80_02385	COG0318	PFAM AMP-dependent synthetase and ligase
GII80_02390	COG2226	methyltransferase
GII80_02395	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_02400	COG1917	Cupin 2, conserved barrel domain protein
GII80_02405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII80_02410	COG3871	stress protein (general stress protein 26)
GII80_02420	COG2814	Major facilitator Superfamily
GII80_02425	COG1522	sequence-specific DNA binding
GII80_02430	COG0551	DNA topoisomerase type I activity
GII80_02430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII80_02435	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII80_02440	COG3706	GGDEF domain
GII80_02445	COG5298	Protein conserved in bacteria
GII80_02450	COG1215	transferase activity, transferring glycosyl groups
GII80_02460	COG0531	amino acid
GII80_02465	COG0494	nUDIX hydrolase
GII80_02470	COG0028	Belongs to the TPP enzyme family
GII80_02485	COG1914	H( )-stimulated, divalent metal cation uptake system
GII80_02490	COG2261	transglycosylase associated protein
GII80_02495	COG4876	unkown
GII80_02500	COG2217	Heavy metal translocating P-type atpase
GII80_02505	COG3729	General stress protein
GII80_02510	COG0662	Cupin 2, conserved barrel domain protein
GII80_02515	COG2329	Antibiotic biosynthesis monooxygenase
GII80_02520	COG3546	catalase activity
GII80_02525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII80_02530	COG3290	protein histidine kinase activity
GII80_02535	COG4565	transcriptional regulatory protein
GII80_02540	COG1301	dicarboxylic acid transport
GII80_02545	COG0628	permease
GII80_02550	COG1131	(ABC) transporter
GII80_02555	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII80_02565	COG1960	acyl-CoA dehydrogenase activity
GII80_02580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII80_02585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_02590	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII80_02595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII80_02600	COG0513	Belongs to the DEAD box helicase family
GII80_02605	COG3402	PFAM membrane-flanked domain
GII80_02610	COG3428	Bacterial PH domain
GII80_02615	COG0705	Rhomboid family
GII80_02620	COG0736	holo-[acyl-carrier-protein] synthase activity
GII80_02625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII80_02630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII80_02635	COG0864	Transcriptional regulator
GII80_02640	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII80_02645	COG1366	Belongs to the anti-sigma-factor antagonist family
GII80_02650	COG1366	Belongs to the anti-sigma-factor antagonist family
GII80_02655	COG2172	sigma factor antagonist activity
GII80_02660	COG2208	phosphoserine phosphatase activity
GII80_02665	COG1366	Belongs to the anti-sigma-factor antagonist family
GII80_02670	COG2172	sigma factor antagonist activity
GII80_02675	COG1191	sigma factor activity
GII80_02680	COG2208	phosphoserine phosphatase activity
GII80_02695	COG1673	EVE domain
GII80_02700	COG1846	Transcriptional regulator
GII80_02705	COG2183	response to ionizing radiation
GII80_02715	COG3091	SprT-like family
GII80_02755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII80_02760	COG1522	sequence-specific DNA binding
GII80_02765	COG1522	sequence-specific DNA binding
GII80_02770	COG1335	isochorismatase
GII80_02775	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII80_02780	COG2814	Major facilitator Superfamily
GII80_02800	COG0693	protein deglycase activity
GII80_02805	COG1278	Cold shock
GII80_02810	COG1329	Transcriptional regulator
GII80_02820	COG2207	Transcriptional regulator
GII80_02820	COG1917	Cupin 2, conserved barrel domain protein
GII80_02825	COG0697	spore germination
GII80_02830	COG3708	Transcriptional regulator
GII80_02830	COG2207	Transcriptional regulator
GII80_02835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII80_02840	COG0477	Major facilitator Superfamily
GII80_02850	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII80_02860	COG0697	spore germination
GII80_02865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII80_02870	COG2030	dehydratase
GII80_02875	COG3545	Serine hydrolase
GII80_02880	COG1733	regulation of RNA biosynthetic process
GII80_02885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII80_02890	COG1733	regulation of RNA biosynthetic process
GII80_02895	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII80_02900	COG2814	Major facilitator Superfamily
GII80_02905	COG1309	transcriptional regulator
GII80_02915	COG0640	Transcriptional regulator
GII80_02920	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII80_02930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII80_02935	COG0697	spore germination
GII80_02940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII80_02945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII80_02950	COG0640	Transcriptional regulator
GII80_02955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII80_02970	COG4585	Histidine kinase
GII80_02975	COG2197	response regulator
GII80_02980	COG2409	Drug exporters of the RND superfamily
GII80_02985	COG0596	Alpha beta hydrolase
GII80_02990	COG1811	Na channel or pump
GII80_02995	COG4978	Transcriptional regulator
GII80_02995	COG0789	Transcriptional regulator
GII80_03000	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII80_03005	COG0778	Nitroreductase
GII80_03010	COG0346	lactoylglutathione lyase activity
GII80_03015	COG2259	Doxx family
GII80_03020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_03035	COG2323	membrane
GII80_03040	COG2323	membrane
GII80_03045	COG0071	Belongs to the small heat shock protein (HSP20) family
GII80_03060	COG1309	transcriptional regulator
GII80_03070	COG0456	acetyltransferase
GII80_03080	COG1113	amino acid transport
GII80_03085	COG2318	DinB family
GII80_03090	COG1846	Transcriptional regulator
GII80_03095	COG1033	growth of symbiont in host cell
GII80_03095	COG2409	Drug exporters of the RND superfamily
GII80_03100	COG0778	Nitroreductase
GII80_03105	COG1846	Transcriptional regulator
GII80_03110	COG2814	Major facilitator Superfamily
GII80_03115	COG0730	response to heat
GII80_03120	COG1802	Transcriptional regulator
GII80_03125	COG3858	chitin binding
GII80_03125	COG1388	LysM domain
GII80_03130	COG1819	glycosyl
GII80_03140	COG1785	Belongs to the alkaline phosphatase family
GII80_03145	COG5646	InterPro IPR014922
GII80_03155	COG0454	-acetyltransferase
GII80_03160	COG1078	dGTPase activity
GII80_03165	COG1388	LysM domain
GII80_03170	COG2814	Major facilitator Superfamily
GII80_03175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII80_03180	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII80_03185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII80_03190	COG2723	6-phospho-beta-galactosidase activity
GII80_03195	COG2188	Transcriptional regulator
GII80_03200	COG1940	carbohydrate kinase activity
GII80_03205	COG1482	cell wall glycoprotein biosynthetic process
GII80_03210	COG4124	Belongs to the glycosyl hydrolase 26 family
GII80_03255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII80_03260	COG0802	atpase or kinase
GII80_03265	COG1214	PFAM Peptidase M22, glycoprotease
GII80_03270	COG0456	acetyltransferase
GII80_03275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII80_03280	COG0488	(ABC) transporter
GII80_03285	COG0315	cyclic pyranopterin monophosphate synthase activity
GII80_03290	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII80_03295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII80_03300	COG0805	protein transport
GII80_03310	COG1266	CAAX protease self-immunity
GII80_03315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GII80_03320	COG0459	protein refolding
GII80_03330	COG3378	Phage plasmid primase P4 family
GII80_03345	COG0270	DNA (cytosine-5-)-methyltransferase activity
GII80_03350	COG0270	DNA (cytosine-5-)-methyltransferase activity
GII80_03370	COG1401	restriction endodeoxyribonuclease activity
GII80_03385	COG1073	alpha beta
GII80_03390	COG0457	Tetratricopeptide repeat
GII80_03395	COG1063	alcohol dehydrogenase
GII80_03400	COG2211	Major facilitator Superfamily
GII80_03405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII80_03410	COG1842	Phage shock protein A
GII80_03415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII80_03420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII80_03425	COG4260	virion core protein, lumpy skin disease virus
GII80_03435	COG2814	Major facilitator Superfamily
GII80_03440	COG1063	alcohol dehydrogenase
GII80_03445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII80_03450	COG0823	Involved in the tonB-independent uptake of proteins
GII80_03465	COG2267	carboxylic ester hydrolase activity
GII80_03475	COG2132	Multicopper oxidase
GII80_03480	COG1113	amino acid transport
GII80_03490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII80_03495	COG0714	Associated with various cellular activities
GII80_03500	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII80_03505	COG1305	Transglutaminase-like
GII80_03510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII80_03510	COG0519	Catalyzes the synthesis of GMP from XMP
GII80_03515	COG2252	PERMEase
GII80_03520	COG3064	Membrane
GII80_03530	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII80_03540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII80_03545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII80_03550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII80_03555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII80_03560	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII80_03565	COG0047	phosphoribosylformylglycinamidine synthase activity
GII80_03570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII80_03575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII80_03580	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII80_03585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII80_03590	COG0138	bifunctional purine biosynthesis protein purh
GII80_03595	COG0151	Belongs to the GarS family
GII80_03600	COG1522	sequence-specific DNA binding
GII80_03605	COG0531	amino acid
GII80_03615	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII80_03620	COG1470	cell adhesion involved in biofilm formation
GII80_03625	COG4496	protein, YerC YecD
GII80_03630	COG0069	glutamate synthase activity
GII80_03635	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII80_03640	COG0210	DNA helicase
GII80_03645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII80_03650	COG4851	CamS sex pheromone cAM373 precursor
GII80_03655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII80_03660	COG1285	pathogenesis
GII80_03665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII80_03670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII80_03675	COG0154	amidase activity
GII80_03680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII80_03685	COG1309	transcriptional regulator
GII80_03690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII80_03695	COG1597	lipid kinase activity
GII80_03700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII80_03705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII80_03710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII80_03715	COG1002	Type II restriction enzyme, methylase subunits
GII80_03720	COG1061	Type III restriction enzyme res subunit
GII80_03725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII80_03745	COG5444	nuclease activity
GII80_03750	COG3391	amine dehydrogenase activity
GII80_03755	COG0457	Tetratricopeptide repeat
GII80_03765	COG0217	transcriptional regulatory protein
GII80_03775	COG1309	transcriptional regulator
GII80_03780	COG3631	Ketosteroid isomerase-related protein
GII80_03785	COG0702	epimerase
GII80_03800	COG3546	catalase activity
GII80_03805	COG0454	-acetyltransferase
GII80_03815	COG5578	integral membrane protein
GII80_03820	COG2972	Histidine kinase
GII80_03825	COG4753	response regulator
GII80_03825	COG2207	Transcriptional regulator
GII80_03830	COG1653	transport
GII80_03835	COG1175	transmembrane transport
GII80_03840	COG0395	ABC-type sugar transport system, permease component
GII80_03845	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII80_03850	COG2207	Transcriptional regulator
GII80_03855	COG2755	lipolytic protein G-D-S-L family
GII80_03865	COG5578	integral membrane protein
GII80_03870	COG3401	FG-GAP repeat protein
GII80_03875	COG3401	FG-GAP repeat protein
GII80_03880	COG2755	lipolytic protein G-D-S-L family
GII80_03885	COG1874	Beta-galactosidase
GII80_03895	COG1653	transport
GII80_03900	COG4209	transmembrane transport
GII80_03905	COG0395	ABC-type sugar transport system, permease component
GII80_03910	COG1486	melibiose metabolic process
GII80_03915	COG2323	membrane
GII80_03920	COG2329	Antibiotic biosynthesis monooxygenase
GII80_03925	COG0346	lactoylglutathione lyase activity
GII80_03940	COG5583	Uncharacterized small protein (DUF2292)
GII80_03945	COG0670	Belongs to the BI1 family
GII80_03950	COG0697	spore germination
GII80_03955	COG1846	Transcriptional regulator
GII80_03960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII80_03970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII80_03970	COG2124	cytochrome p450
GII80_03975	COG1368	sulfuric ester hydrolase activity
GII80_03980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII80_03985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII80_03990	COG1442	glycosyl transferase family 8
GII80_03995	COG1216	Glycosyl transferase, family 2
GII80_04000	COG1442	glycosyl transferase family 8
GII80_04005	COG2223	nitrite transmembrane transporter activity
GII80_04010	COG1011	Hydrolase
GII80_04015	COG0531	amino acid
GII80_04020	COG1012	belongs to the aldehyde dehydrogenase family
GII80_04025	COG0840	transmembrane signaling receptor activity
GII80_04030	COG0488	(ABC) transporter
GII80_04040	COG0789	Transcriptional regulator
GII80_04045	COG2814	Major facilitator Superfamily
GII80_04055	COG0488	(ABC) transporter
GII80_04060	COG0513	Belongs to the DEAD box helicase family
GII80_04065	COG0456	acetyltransferase
GII80_04070	COG2130	NADP-dependent
GII80_04075	COG2211	Major facilitator Superfamily
GII80_04080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GII80_04085	COG1120	ATPase activity
GII80_04090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII80_04095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII80_04100	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII80_04115	COG3866	Pectate lyase
GII80_04120	COG0471	metal ion transport
GII80_04125	COG3290	protein histidine kinase activity
GII80_04130	COG4565	transcriptional regulatory protein
GII80_04135	COG3181	Tripartite tricarboxylate transporter family receptor
GII80_04140	COG2851	Citrate transporter
GII80_04145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII80_04150	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII80_04155	COG1254	Belongs to the acylphosphatase family
GII80_04160	COG2258	MOSC domain
GII80_04180	COG0024	Methionine aminopeptidase
GII80_04185	COG1263	PTS System
GII80_04185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_04190	COG1368	sulfuric ester hydrolase activity
GII80_04205	COG1115	amino acid carrier protein
GII80_04210	COG0531	amino acid
GII80_04225	COG0697	spore germination
GII80_04230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_04230	COG1263	PTS System
GII80_04235	COG0366	Alpha amylase catalytic
GII80_04240	COG2188	Transcriptional regulator
GII80_04245	COG0778	Nitroreductase
GII80_04250	COG0737	Belongs to the 5'-nucleotidase family
GII80_04255	COG0693	protein deglycase activity
GII80_04260	COG2814	Major facilitator Superfamily
GII80_04265	COG4840	Belongs to the UPF0435 family
GII80_04270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII80_04275	COG4980	gas vesicle protein
GII80_04280	COG1295	ribonuclease BN
GII80_04285	COG0477	Major facilitator Superfamily
GII80_04295	COG0387	Pfam Sodium calcium exchanger
GII80_04305	COG0668	transmembrane transport
GII80_04310	COG0535	radical SAM domain protein
GII80_04320	COG0726	polysaccharide deacetylase
GII80_04325	COG2084	Dehydrogenase
GII80_04330	COG0598	Magnesium transport protein CorA
GII80_04335	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII80_04340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII80_04350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII80_04355	COG4637	Psort location Cytoplasmic, score
GII80_04365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII80_04370	COG0022	dehydrogenase e1 component
GII80_04375	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII80_04380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII80_04385	COG3284	Transcriptional regulator
GII80_04395	COG1742	UPF0060 membrane protein
GII80_04420	COG4842	Belongs to the WXG100 family
GII80_04425	COG1486	melibiose metabolic process
GII80_04430	COG1737	Transcriptional regulator
GII80_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_04435	COG1263	PTS System
GII80_04440	COG1132	(ABC) transporter
GII80_04445	COG1132	(ABC) transporter
GII80_04450	COG2259	Doxx family
GII80_04455	COG2514	catechol 2,3-dioxygenase activity
GII80_04460	COG4977	sequence-specific DNA binding
GII80_04460	COG1917	Cupin 2, conserved barrel domain protein
GII80_04465	COG2814	Major facilitator Superfamily
GII80_04470	COG1082	Xylose isomerase domain protein TIM barrel
GII80_04475	COG0673	inositol 2-dehydrogenase activity
GII80_04480	COG4585	Histidine kinase
GII80_04485	COG2197	response regulator
GII80_04490	COG1131	(ABC) transporter
GII80_04495	COG0842	Transport permease protein
GII80_04495	COG1511	domain protein
GII80_04500	COG0842	Transport permease protein
GII80_04505	COG1695	Transcriptional regulator
GII80_04510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII80_04515	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII80_04520	COG1309	transcriptional regulator
GII80_04525	COG2814	Major facilitator Superfamily
GII80_04530	COG2318	DinB family
GII80_04535	COG2814	Major facilitator Superfamily
GII80_04540	COG1846	Transcriptional regulator
GII80_04545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII80_04545	COG0392	lysyltransferase activity
GII80_04550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII80_04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII80_04560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII80_04565	COG0384	phenazine biosynthesis protein PhzF
GII80_04570	COG0778	Nitroreductase
GII80_04585	COG1090	epimerase
GII80_04590	COG2137	regulation of response to DNA damage stimulus
GII80_04600	COG2814	Major facilitator Superfamily
GII80_04615	COG3103	Sh3 type 3 domain protein
GII80_04620	COG5658	integral membrane protein
GII80_04625	COG0596	Alpha beta hydrolase
GII80_04630	COG0463	Glycosyl transferase, family 2
GII80_04635	COG4485	Bacterial membrane protein, YfhO
GII80_04640	COG1988	membrane-bound metal-dependent
GII80_04645	COG1194	a g-specific adenine glycosylase
GII80_04655	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_04670	COG3557	Belongs to the UPF0374 family
GII80_04675	COG1132	(ABC) transporter
GII80_04680	COG4129	membrane
GII80_04685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII80_04690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII80_04695	COG0735	belongs to the Fur family
GII80_04805	COG4326	sporulation control protein
GII80_04815	COG5577	PFAM Coat F domain
GII80_04820	COG3340	Belongs to the peptidase S51 family
GII80_04825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII80_04830	COG0277	FAD linked oxidase domain protein
GII80_04840	COG0753	catalase activity
GII80_04845	COG1116	anion transmembrane transporter activity
GII80_04850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII80_04855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII80_04860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII80_04870	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII80_04880	COG1476	TRANSCRIPTIONal
GII80_04890	COG3382	B3 4 domain protein
GII80_04895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII80_04905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII80_04910	COG0789	Transcriptional regulator
GII80_04915	COG1664	Polymer-forming cytoskeletal
GII80_04920	COG1664	Polymer-forming cytoskeletal
GII80_04925	COG2766	serine protein kinase
GII80_04930	COG2718	Belongs to the UPF0229 family
GII80_04935	COG1846	Transcriptional regulator
GII80_04940	COG1566	PFAM secretion protein HlyD family protein
GII80_04945	COG2814	Major facilitator Superfamily
GII80_04950	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII80_04970	COG1725	Transcriptional regulator
GII80_04975	COG1131	(ABC) transporter
GII80_04980	COG1131	(ABC) transporter
GII80_04985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII80_04990	COG1278	Cold shock
GII80_04995	COG1464	Belongs to the NlpA lipoprotein family
GII80_05000	COG3706	GGDEF domain
GII80_05005	COG1823	symporter activity
GII80_05025	COG5577	PFAM Coat F domain
GII80_05030	COG0737	Belongs to the 5'-nucleotidase family
GII80_05030	COG4085	toxin activity
GII80_05030	COG1525	nuclease
GII80_05035	COG3764	Sortase (surface protein transpeptidase)
GII80_05040	COG0564	pseudouridine synthase activity
GII80_05050	COG0517	IMP dehydrogenase activity
GII80_05055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII80_05060	COG3153	acetyltransferase
GII80_05060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII80_05065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII80_05070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII80_05075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII80_05080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII80_05085	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII80_05090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII80_05095	COG2203	Gaf domain
GII80_05095	COG4585	Histidine kinase
GII80_05100	COG2197	response regulator
GII80_05105	COG0431	NADPH-dependent FMN reductase
GII80_05120	COG0791	NLP P60 protein
GII80_05120	COG1388	LysM domain
GII80_05125	COG1959	2 iron, 2 sulfur cluster binding
GII80_05130	COG0668	transmembrane transport
GII80_05135	COG2719	SpoVR family
GII80_05140	COG1785	Belongs to the alkaline phosphatase family
GII80_05145	COG0791	NLP P60 protein
GII80_05145	COG1388	LysM domain
GII80_05150	COG0583	DNA-binding transcription factor activity
GII80_05155	COG0372	Belongs to the citrate synthase family
GII80_05160	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_05165	COG0531	amino acid
GII80_05170	COG0733	neurotransmitter:sodium symporter activity
GII80_05175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII80_05180	COG0456	acetyltransferase
GII80_05195	COG1595	DNA-templated transcription, initiation
GII80_05200	COG0667	Aldo Keto reductase
GII80_05205	COG0204	Acyl-transferase
GII80_05210	COG1253	flavin adenine dinucleotide binding
GII80_05215	COG0789	Transcriptional regulator
GII80_05220	COG0436	Aminotransferase
GII80_05225	COG1253	flavin adenine dinucleotide binding
GII80_05230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII80_05235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII80_05240	COG0584	glycerophosphoryl diester phosphodiesterase
GII80_05250	COG0668	transmembrane transport
GII80_05255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII80_05260	COG0726	polysaccharide deacetylase
GII80_05265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII80_05270	COG1757	Na H antiporter
GII80_05275	COG0589	response to stress
GII80_05285	COG1132	(ABC) transporter
GII80_05290	COG1132	(ABC) transporter
GII80_05295	COG0702	epimerase
GII80_05315	COG0189	ligase activity
GII80_05320	COG0189	ligase activity
GII80_05325	COG4399	Belongs to the UPF0754 family
GII80_05330	COG3679	Belongs to the UPF0342 family
GII80_05335	COG4335	DNA alkylation repair
GII80_05340	COG0561	phosphatase activity
GII80_05345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII80_05350	COG0475	glutathione-regulated potassium exporter activity
GII80_05355	COG0490	domain, Protein
GII80_05365	COG1024	Enoyl-CoA hydratase
GII80_05375	COG4152	abc transporter atp-binding protein
GII80_05380	COG1668	transmembrane transport
GII80_05385	COG0420	3'-5' exonuclease activity
GII80_05390	COG4717	serine-type aminopeptidase activity
GII80_05395	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII80_05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII80_05435	COG1846	Transcriptional regulator
GII80_05440	COG4980	gas vesicle protein
GII80_05455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII80_05460	COG0537	adenosine 5'-monophosphoramidase activity
GII80_05465	COG1131	(ABC) transporter
GII80_05470	COG4473	ABC transporter
GII80_05480	COG1473	amidohydrolase
GII80_05485	COG3069	C4-dicarboxylate transmembrane transporter activity
GII80_05495	COG2329	Antibiotic biosynthesis monooxygenase
GII80_05500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII80_05505	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII80_05520	COG1309	transcriptional regulator
GII80_05525	COG1511	domain protein
GII80_05530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII80_05535	COG4377	Putative membrane peptidase family (DUF2324)
GII80_05545	COG1363	Peptidase, m42
GII80_05550	COG4405	Protein conserved in bacteria
GII80_05555	COG1301	dicarboxylic acid transport
GII80_05565	COG1234	tRNA 3'-trailer cleavage
GII80_05570	COG0095	Lipoate-protein ligase
GII80_05575	COG0702	epimerase
GII80_05580	COG0318	PFAM AMP-dependent synthetase and ligase
GII80_05590	COG0501	Belongs to the peptidase M48B family
GII80_05595	COG1404	Belongs to the peptidase S8 family
GII80_05600	COG0456	acetyltransferase
GII80_05605	COG0604	alcohol dehydrogenase
GII80_05610	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII80_05615	COG0406	alpha-ribazole phosphatase activity
GII80_05620	COG0183	Belongs to the thiolase family
GII80_05625	COG0318	PFAM AMP-dependent synthetase and ligase
GII80_05630	COG1268	BioY protein
GII80_05635	COG0840	transmembrane signaling receptor activity
GII80_05640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII80_05640	COG0723	plastoquinol--plastocyanin reductase activity
GII80_05645	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_05655	COG4903	ComK protein
GII80_05660	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_05670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII80_05685	COG0398	Pfam SNARE associated Golgi protein
GII80_05690	COG0681	Belongs to the peptidase S26 family
GII80_05695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII80_05700	COG1846	Transcriptional regulator
GII80_05705	COG0738	Major facilitator superfamily
GII80_05710	COG0673	inositol 2-dehydrogenase activity
GII80_05715	COG0561	phosphatase activity
GII80_05720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII80_05725	COG1609	Transcriptional regulator
GII80_05730	COG3180	Ammonia monooxygenase
GII80_05735	COG0477	Major facilitator Superfamily
GII80_05735	COG2814	Major facilitator Superfamily
GII80_05740	COG4533	DNA binding
GII80_05750	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII80_05755	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII80_05760	COG1074	ATP-dependent DNA helicase activity
GII80_05765	COG0420	3'-5' exonuclease activity
GII80_05770	COG0419	ATPase involved in DNA repair
GII80_05775	COG1403	HNH endonuclease
GII80_05815	COG5337	Spore coat protein CotH
GII80_05820	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII80_05830	COG1404	Belongs to the peptidase S8 family
GII80_05840	COG0367	asparagine synthase
GII80_05845	COG2318	DinB family
GII80_05850	COG1562	ergosterol biosynthetic process
GII80_05855	COG0534	Mate efflux family protein
GII80_05860	COG2207	Transcriptional regulator
GII80_05860	COG1917	Cupin 2, conserved barrel domain protein
GII80_05865	COG1609	Transcriptional regulator
GII80_05870	COG0673	inositol 2-dehydrogenase activity
GII80_05875	COG2318	DinB family
GII80_05880	COG1279	arginine transmembrane transporter activity
GII80_05885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII80_05890	COG1357	PFAM Pentapeptide repeats (8 copies)
GII80_05895	COG2267	carboxylic ester hydrolase activity
GII80_05900	COG0529	Catalyzes the synthesis of activated sulfate
GII80_05905	COG2046	Belongs to the sulfate adenylyltransferase family
GII80_05910	COG0175	sulfate reduction
GII80_05915	COG2045	Belongs to the ComB family
GII80_05920	COG1809	phosphosulfolactate synthase activity
GII80_05925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII80_05930	COG4948	Mandelate Racemase Muconate Lactonizing
GII80_05935	COG2814	Major facilitator Superfamily
GII80_05940	COG0454	-acetyltransferase
GII80_05945	COG2153	protein acetylation
GII80_05950	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII80_05950	COG0646	methionine synthase
GII80_05955	COG1666	GTP binding
GII80_05960	COG2996	Protein conserved in bacteria
GII80_05980	COG1695	Transcriptional regulator
GII80_05995	COG3227	Zinc metalloprotease (Elastase)
GII80_06000	COG1307	EDD domain protein, DegV family
GII80_06005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII80_06020	COG0561	phosphatase activity
GII80_06025	COG1073	alpha beta
GII80_06030	COG2151	metal-sulfur cluster biosynthetic enzyme
GII80_06040	COG0277	FAD linked oxidase domain protein
GII80_06045	COG2271	Major facilitator Superfamily
GII80_06050	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII80_06065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII80_06070	COG0505	Belongs to the CarA family
GII80_06075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII80_06080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII80_06095	COG2267	carboxylic ester hydrolase activity
GII80_06105	COG1744	ABC transporter substrate-binding protein PnrA-like
GII80_06120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII80_06125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII80_06130	COG5504	Zn-dependent protease
GII80_06135	COG0444	Belongs to the ABC transporter superfamily
GII80_06140	COG4608	Belongs to the ABC transporter superfamily
GII80_06150	COG0601	transmembrane transport
GII80_06155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII80_06165	COG0180	Tryptophanyl-tRNA synthetase
GII80_06170	COG4166	transmembrane transport
GII80_06175	COG0601	transmembrane transport
GII80_06180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII80_06185	COG0444	Belongs to the ABC transporter superfamily
GII80_06190	COG4608	Belongs to the ABC transporter superfamily
GII80_06195	COG2814	Major facilitator Superfamily
GII80_06200	COG0456	acetyltransferase
GII80_06205	COG1393	Belongs to the ArsC family
GII80_06210	COG0861	Integral membrane protein TerC family
GII80_06220	COG4862	establishment of competence for transformation
GII80_06230	COG4469	Competence protein
GII80_06235	COG1164	Oligoendopeptidase f
GII80_06250	COG2346	COG2346, Truncated hemoglobins
GII80_06255	COG0741	lytic transglycosylase activity
GII80_06260	COG4116	CYTH
GII80_06270	COG2357	RelA SpoT domain protein
GII80_06275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII80_06280	COG0564	pseudouridine synthase activity
GII80_06285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII80_06290	COG0475	glutathione-regulated potassium exporter activity
GII80_06290	COG0569	domain protein
GII80_06295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII80_06300	COG0352	thiamine-phosphate diphosphorylase activity
GII80_06305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII80_06310	COG2104	thiamine diphosphate biosynthetic process
GII80_06315	COG2022	thiamine diphosphate biosynthetic process
GII80_06320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII80_06325	COG0351	phosphomethylpyrimidine kinase
GII80_06330	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII80_06385	COG0210	DNA helicase
GII80_06395	COG2153	protein acetylation
GII80_06400	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII80_06405	COG2382	esterase
GII80_06410	COG0626	cystathionine gamma-synthase activity
GII80_06415	COG0626	cystathionine gamma-synthase activity
GII80_06420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII80_06425	COG5505	Protein of unknown function (DUF819)
GII80_06455	COG3677	Transposase
GII80_06470	COG5484	DNA packaging
GII80_06475	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII80_06480	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_06495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII80_06495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII80_06495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII80_06500	COG1482	cell wall glycoprotein biosynthetic process
GII80_06510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII80_06520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII80_06535	COG0109	protoheme IX farnesyltransferase activity
GII80_06545	COG0726	polysaccharide deacetylase
GII80_06560	COG5504	Zn-dependent protease
GII80_06565	COG2205	protein histidine kinase activity
GII80_06575	COG3383	formate dehydrogenase (NAD+) activity
GII80_06580	COG2427	Protein of unknown function (DUF1641)
GII80_06590	COG1051	belongs to the nudix hydrolase family
GII80_06600	COG2124	cytochrome p450
GII80_06605	COG1819	glycosyl
GII80_06615	COG1587	Uroporphyrinogen-III synthase
GII80_06620	COG0390	transport system, permease component
GII80_06625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII80_06630	COG0697	spore germination
GII80_06635	COG4297	protein containing double-stranded beta helix domain
GII80_06645	COG1252	NADH dehydrogenase
GII80_06650	COG1904	glucuronate isomerase
GII80_06655	COG2211	Major facilitator Superfamily
GII80_06660	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII80_06665	COG1063	alcohol dehydrogenase
GII80_06670	COG1312	Catalyzes the dehydration of D-mannonate
GII80_06675	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_06680	COG2271	Major facilitator Superfamily
GII80_06685	COG1609	Transcriptional regulator
GII80_06690	COG0246	Mannitol dehydrogenase
GII80_06695	COG2721	sulfolactate sulfo-lyase activity
GII80_06700	COG0730	response to heat
GII80_06705	COG2318	DinB family
GII80_06710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII80_06715	COG0457	Tetratricopeptide repeat
GII80_06725	COG2350	Protein conserved in bacteria
GII80_06730	COG1388	LysM domain
GII80_06730	COG3409	Peptidoglycan-binding domain 1 protein
GII80_06730	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII80_06740	COG4195	phage-related replication protein
GII80_06745	COG3546	catalase activity
GII80_06750	COG2856	Zn peptidase
GII80_06755	COG1396	sequence-specific DNA binding
GII80_06765	COG1522	sequence-specific DNA binding
GII80_06770	COG1484	DNA-dependent DNA replication
GII80_06790	COG1595	DNA-templated transcription, initiation
GII80_06795	COG5484	DNA packaging
GII80_06795	COG3728	DNA packaging
GII80_06800	COG1783	phage Terminase large subunit
GII80_06805	COG5518	Phage portal protein
GII80_06810	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII80_06815	COG4653	Phage capsid family
GII80_06865	COG3953	SLT domain
GII80_06865	COG5412	phage tail tape measure protein
GII80_06870	COG1652	LysM domain
GII80_06875	COG4193	domain, Protein
GII80_06885	COG3628	GPW Gp25 family protein
GII80_06890	COG3299	homolog of phage Mu protein gp47
GII80_06895	COG3778	Protein conserved in bacteria
GII80_06935	COG3409	Peptidoglycan-binding domain 1 protein
GII80_06935	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII80_06955	COG0306	phosphate transporter
GII80_06960	COG1392	Phosphate transport regulator
GII80_06965	COG0531	amino acid
GII80_06970	COG0346	lactoylglutathione lyase activity
GII80_06980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII80_06985	COG0463	Glycosyl transferase, family 2
GII80_06990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII80_06995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII80_07000	COG2362	D-Aminopeptidase
GII80_07005	COG0601	transmembrane transport
GII80_07010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII80_07015	COG0444	Belongs to the ABC transporter superfamily
GII80_07020	COG4166	transmembrane transport
GII80_07025	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII80_07030	COG4948	Mandelate Racemase Muconate Lactonizing
GII80_07035	COG0791	NLP P60 protein
GII80_07040	COG4608	Belongs to the ABC transporter superfamily
GII80_07045	COG2706	6-phosphogluconolactonase activity
GII80_07050	COG1834	amidinotransferase
GII80_07055	COG1607	acyl-coa hydrolase
GII80_07060	COG1017	nitric oxide dioxygenase activity
GII80_07060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII80_07070	COG2323	membrane
GII80_07075	COG2318	DinB family
GII80_07080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII80_07085	COG2076	Multidrug Resistance protein
GII80_07090	COG2076	Multidrug Resistance protein
GII80_07095	COG0788	formyltetrahydrofolate deformylase activity
GII80_07100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII80_07105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII80_07110	COG1764	response to oxidative stress
GII80_07115	COG1846	Transcriptional regulator
GII80_07120	COG1764	response to oxidative stress
GII80_07130	COG0590	tRNA wobble adenosine to inosine editing
GII80_07135	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII80_07140	COG1404	Belongs to the peptidase S8 family
GII80_07145	COG1366	Belongs to the anti-sigma-factor antagonist family
GII80_07150	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII80_07155	COG1122	ATPase activity
GII80_07160	COG4721	ABC-type cobalt transport system, permease component
GII80_07170	COG0745	RESPONSE REGULATOR receiver
GII80_07175	COG3850	Histidine kinase
GII80_07175	COG5002	protein histidine kinase activity
GII80_07180	COG3212	peptidase
GII80_07185	COG3212	peptidase
GII80_07195	COG2239	Acts as a magnesium transporter
GII80_07200	COG0789	Transcriptional regulator
GII80_07215	COG1846	Transcriptional regulator
GII80_07220	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII80_07225	COG0726	polysaccharide deacetylase
GII80_07230	COG1408	metallophosphoesterase
GII80_07240	COG0463	Glycosyl transferase, family 2
GII80_07245	COG1793	dna ligase
GII80_07245	COG3285	dna ligase
GII80_07250	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII80_07255	COG3300	MHYT domain
GII80_07255	COG5001	Diguanylate cyclase
GII80_07260	COG0586	Pfam SNARE associated Golgi protein
GII80_07265	COG0861	Integral membrane protein TerC family
GII80_07270	COG1191	sigma factor activity
GII80_07290	COG0501	Belongs to the peptidase M48B family
GII80_07295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII80_07310	COG3594	Acyltransferase
GII80_07315	COG5002	protein histidine kinase activity
GII80_07320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII80_07330	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII80_07335	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII80_07340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII80_07345	COG0436	Aminotransferase
GII80_07350	COG1850	ribulose-bisphosphate carboxylase activity
GII80_07355	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII80_07360	COG0235	Class ii aldolase
GII80_07365	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII80_07370	COG3339	Conserved Protein
GII80_07385	COG3852	Histidine kinase
GII80_07390	COG1846	Transcriptional regulator
GII80_07395	COG1360	Flagellar Motor Protein
GII80_07400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII80_07405	COG0542	response to heat
GII80_07410	COG3949	Membrane
GII80_07415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII80_07420	COG0720	synthase
GII80_07425	COG0602	queuosine metabolic process
GII80_07430	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII80_07435	COG1733	regulation of RNA biosynthetic process
GII80_07440	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_07445	COG4641	Protein conserved in bacteria
GII80_07445	COG1388	LysM domain
GII80_07450	COG1388	LysM domain
GII80_07465	COG4873	Protein conserved in bacteria
GII80_07475	COG3773	Cell wall hydrolase
GII80_07480	COG2244	polysaccharide biosynthetic process
GII80_07485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_07490	COG2217	Heavy metal translocating P-type atpase
GII80_07500	COG0006	proline dipeptidase activity
GII80_07505	COG1609	Transcriptional regulator
GII80_07510	COG3711	transcriptional antiterminator
GII80_07515	COG1263	PTS System
GII80_07515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_07515	COG2190	(PTS) system
GII80_07520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII80_07525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII80_07535	COG1533	DNA photolyase activity
GII80_07540	COG0456	acetyltransferase
GII80_07545	COG0840	transmembrane signaling receptor activity
GII80_07550	COG2084	Dehydrogenase
GII80_07555	COG2340	Cysteine-rich secretory protein family
GII80_07560	COG0768	penicillin binding
GII80_07565	COG4191	Histidine kinase
GII80_07570	COG0436	Aminotransferase
GII80_07580	COG0784	Response regulator, receiver
GII80_07580	COG0835	chemotaxis
GII80_07590	COG2814	Major facilitator Superfamily
GII80_07595	COG1376	ErfK ybiS ycfS ynhG family protein
GII80_07600	COG1408	metallophosphoesterase
GII80_07605	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_07610	COG3409	Peptidoglycan-binding domain 1 protein
GII80_07615	COG3409	Peptidoglycan-binding domain 1 protein
GII80_07625	COG2200	EAL domain
GII80_07630	COG4703	Protein of unknown function (DUF1797)
GII80_07635	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII80_07645	COG0517	IMP dehydrogenase activity
GII80_07650	COG0583	DNA-binding transcription factor activity
GII80_07655	COG0716	FMN binding
GII80_07665	COG0716	FMN binding
GII80_07670	COG2171	N-acyltransferase activity
GII80_07675	COG1473	amidohydrolase
GII80_07685	COG0668	transmembrane transport
GII80_07690	COG0450	alkyl hydroperoxide reductase
GII80_07695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_07710	COG0746	molybdenum cofactor guanylyltransferase activity
GII80_07715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII80_07720	COG0303	'Molybdopterin
GII80_07725	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII80_07730	COG0314	molybdopterin synthase activity
GII80_07735	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII80_07740	COG1132	(ABC) transporter
GII80_07745	COG1132	(ABC) transporter
GII80_07755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII80_07760	COG1136	(ABC) transporter
GII80_07765	COG0577	efflux transmembrane transporter activity
GII80_07770	COG1349	DNA-binding transcription factor activity
GII80_07775	COG1105	Belongs to the carbohydrate kinase PfkB family
GII80_07780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII80_07780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII80_07780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII80_07785	COG0681	Belongs to the peptidase S26 family
GII80_07795	COG0488	(ABC) transporter
GII80_07800	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII80_07805	COG2309	aminopeptidase activity
GII80_07815	COG1077	Cell shape determining protein MreB Mrl
GII80_07820	COG2002	toxin-antitoxin pair type II binding
GII80_07825	COG3852	Histidine kinase
GII80_07830	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII80_07830	COG2105	PFAM AIG2 family protein
GII80_07835	COG0569	domain protein
GII80_07840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII80_07845	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII80_07855	COG0561	phosphatase activity
GII80_07860	COG0242	peptide deformylase activity
GII80_07870	COG0497	DNA recombination
GII80_07875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII80_07880	COG0022	dehydrogenase e1 component
GII80_07885	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII80_07890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII80_07895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_07905	COG1982	Orn Lys Arg decarboxylase major
GII80_07910	COG4476	Belongs to the UPF0223 family
GII80_07915	COG4493	Belongs to the UPF0637 family
GII80_07925	COG0483	inositol monophosphate 1-phosphatase activity
GII80_07935	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII80_07955	COG1595	DNA-templated transcription, initiation
GII80_07985	COG4896	Protein conserved in bacteria
GII80_07995	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII80_08000	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII80_08005	COG2066	Belongs to the glutaminase family
GII80_08010	COG4838	Belongs to the UPF0358 family
GII80_08015	COG0772	Belongs to the SEDS family
GII80_08020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII80_08025	COG1612	heme a metabolic process
GII80_08030	COG0109	protoheme IX farnesyltransferase activity
GII80_08035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII80_08035	COG2010	Cytochrome c
GII80_08040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII80_08045	COG1845	cytochrome c oxidase, subunit III
GII80_08050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII80_08055	COG3336	cytochrome c oxidase
GII80_08065	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII80_08070	COG2340	Cysteine-rich secretory protein family
GII80_08085	COG3679	Belongs to the UPF0342 family
GII80_08090	COG4471	UPF0298 protein
GII80_08095	COG0742	ribosomal rna small subunit methyltransferase
GII80_08100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII80_08105	COG3314	Sporulation integral membrane protein YlbJ
GII80_08110	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII80_08115	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII80_08120	COG1323	Belongs to the UPF0348 family
GII80_08130	COG1399	metal-binding, possibly nucleic acid-binding protein
GII80_08135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GII80_08145	COG0454	-acetyltransferase
GII80_08150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII80_08155	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII80_08160	COG2001	Belongs to the MraZ family
GII80_08165	COG0275	rRNA processing
GII80_08170	COG4839	cell division protein FtsL
GII80_08180	COG0768	penicillin binding
GII80_08185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII80_08190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII80_08195	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII80_08200	COG0772	Belongs to the SEDS family
GII80_08205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII80_08210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII80_08215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII80_08220	COG3879	Bacterial protein of unknown function (DUF881)
GII80_08225	COG3879	Bacterial protein of unknown function (DUF881)
GII80_08230	COG3856	small basic protein
GII80_08235	COG0849	cell division
GII80_08240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII80_08245	COG1404	Belongs to the peptidase S8 family
GII80_08245	COG4412	M6 family metalloprotease domain protein
GII80_08255	COG1191	sigma factor activity
GII80_08260	COG1191	sigma factor activity
GII80_08265	COG1119	ATPase activity
GII80_08270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII80_08275	COG1873	PFAM PRC-barrel domain
GII80_08285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII80_08290	COG1799	cell septum assembly
GII80_08295	COG0762	integral membrane protein
GII80_08300	COG2302	S4 RNA-binding domain
GII80_08305	COG3599	regulation of cell shape
GII80_08310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII80_08315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII80_08320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII80_08325	COG0564	pseudouridine synthase activity
GII80_08330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII80_08335	COG2233	PERMEase
GII80_08340	COG0540	Belongs to the ATCase OTCase family
GII80_08345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII80_08350	COG0505	Belongs to the CarA family
GII80_08355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII80_08360	COG0543	2 iron, 2 sulfur cluster binding
GII80_08365	COG0167	dihydroorotate dehydrogenase activity
GII80_08370	COG0284	orotidine-5'-phosphate decarboxylase activity
GII80_08375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII80_08380	COG0175	sulfate reduction
GII80_08385	COG0306	phosphate transporter
GII80_08390	COG2046	Belongs to the sulfate adenylyltransferase family
GII80_08395	COG0529	Catalyzes the synthesis of activated sulfate
GII80_08400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII80_08405	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII80_08410	COG1648	precorrin-2 dehydrogenase activity
GII80_08420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII80_08425	COG1561	YicC-like family, N-terminal region
GII80_08430	COG2052	Domain of unknown function (DUF370)
GII80_08435	COG0194	GDP metabolic process
GII80_08440	COG1758	RNA polymerase activity
GII80_08445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII80_08450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII80_08455	COG0242	peptide deformylase activity
GII80_08460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII80_08465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII80_08465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII80_08470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII80_08475	COG0631	protein serine/threonine phosphatase activity
GII80_08480	COG2815	serine threonine protein kinase
GII80_08480	COG0515	serine threonine protein kinase
GII80_08485	COG1162	GTPase activity
GII80_08490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII80_08495	COG1564	THIamine pyrophosphokinase
GII80_08505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII80_08510	COG1302	Protein conserved in bacteria
GII80_08515	COG1461	Dihydroxyacetone kinase
GII80_08520	COG1760	l-serine dehydratase
GII80_08525	COG1760	l-serine dehydratase
GII80_08530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII80_08535	COG1349	DNA-binding transcription factor activity
GII80_08535	COG2050	protein possibly involved in aromatic compounds catabolism
GII80_08540	COG0416	fatty acid biosynthetic process
GII80_08545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII80_08550	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII80_08560	COG0571	ribonuclease III activity
GII80_08565	COG1196	nuclear chromosome segregation
GII80_08570	COG0552	protein localization to endoplasmic reticulum
GII80_08580	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII80_08585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII80_08590	COG0228	four-way junction DNA binding
GII80_08595	COG1837	Belongs to the UPF0109 family
GII80_08605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII80_08610	COG0336	Belongs to the RNA methyltransferase TrmD family
GII80_08615	COG0335	large ribosomal subunit rRNA binding
GII80_08620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII80_08625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII80_08635	COG2257	FlhB HrpN YscU SpaS Family
GII80_08640	COG0045	succinate-CoA ligase (ADP-forming) activity
GII80_08645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII80_08650	COG0758	DNA mediated transformation
GII80_08655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII80_08660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII80_08665	COG4974	Belongs to the 'phage' integrase family
GII80_08670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII80_08675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII80_08680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII80_08685	COG1815	bacterial-type flagellum-dependent cell motility
GII80_08690	COG1558	bacterial-type flagellum-dependent cell motility
GII80_08695	COG1677	Flagellar hook-basal body complex protein FliE
GII80_08700	COG1766	The M ring may be actively involved in energy transduction
GII80_08705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII80_08710	COG1317	bacterial-type flagellum organization
GII80_08715	COG1157	protein secretion by the type III secretion system
GII80_08720	COG2882	bacterial-type flagellum organization
GII80_08725	COG3334	PFAM MgtE intracellular
GII80_08730	COG3144	bacterial-type flagellum assembly
GII80_08735	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII80_08740	COG4786	Flagellar basal body rod
GII80_08745	COG1582	Flagellar protein (FlbD)
GII80_08750	COG1580	Controls the rotational direction of flagella during chemotaxis
GII80_08755	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII80_08760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII80_08760	COG1776	CheC inhibitor of MCP methylation
GII80_08765	COG2201	protein-glutamate methylesterase activity
GII80_08770	COG3190	flagellar
GII80_08775	COG1338	Plays a role in the flagellum-specific transport system
GII80_08780	COG1987	bacterial-type flagellum assembly
GII80_08785	COG1684	flagellar biosynthetic protein fliR
GII80_08790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII80_08795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII80_08800	COG1419	protein localization to endoplasmic reticulum
GII80_08805	COG0455	bacterial-type flagellum organization
GII80_08810	COG2201	protein-glutamate methylesterase activity
GII80_08815	COG2198	Histidine kinase
GII80_08815	COG0643	Histidine kinase
GII80_08820	COG0835	chemotaxis
GII80_08825	COG1776	CheC inhibitor of MCP methylation
GII80_08830	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII80_08835	COG1191	sigma factor activity
GII80_08845	COG0052	Belongs to the universal ribosomal protein uS2 family
GII80_08850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII80_08855	COG0528	UMP kinase activity
GII80_08860	COG0233	cytoplasmic translational termination
GII80_08865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII80_08870	COG4589	Belongs to the CDS family
GII80_08875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII80_08880	COG0750	zinc metalloprotease
GII80_08885	COG0442	prolyl-tRNA aminoacylation
GII80_08890	COG2176	DNA-directed DNA polymerase activity
GII80_08895	COG0779	Required for maturation of 30S ribosomal subunits
GII80_08900	COG0195	Participates in both transcription termination and antitermination
GII80_08905	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII80_08910	COG1358	cellular component organization or biogenesis
GII80_08915	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII80_08920	COG1550	Protein conserved in bacteria
GII80_08925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII80_08930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII80_08935	COG0196	riboflavin kinase activity
GII80_08940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII80_08945	COG1185	polyribonucleotide nucleotidyltransferase activity
GII80_08950	COG0726	polysaccharide deacetylase
GII80_08955	COG0612	Peptidase, M16
GII80_08960	COG1873	PFAM PRC-barrel domain
GII80_08965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII80_08970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII80_08975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII80_08980	COG0527	aspartate kinase activity
GII80_08985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII80_08990	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII80_08995	COG0740	serine-type endopeptidase activity
GII80_09005	COG4980	gas vesicle protein
GII80_09005	COG1674	ftsk spoiiie
GII80_09010	COG2188	Transcriptional regulator
GII80_09015	COG2814	Major facilitator Superfamily
GII80_09020	COG0612	Peptidase, M16
GII80_09025	COG0612	Peptidase, M16
GII80_09030	COG0300	oxidoreductase activity
GII80_09045	COG1426	Protein conserved in bacteria
GII80_09050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII80_09055	COG1058	Belongs to the CinA family
GII80_09055	COG1546	Belongs to the CinA family
GII80_09060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII80_09065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII80_09070	COG1418	mRNA catabolic process
GII80_09075	COG1692	metallophosphoesterase
GII80_09080	COG2359	stage V sporulation protein S
GII80_09085	COG1063	alcohol dehydrogenase
GII80_09090	COG0156	8-amino-7-oxononanoate synthase activity
GII80_09095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII80_09100	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII80_09110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII80_09115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII80_09130	COG3226	Transcriptional regulator
GII80_09135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII80_09145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII80_09150	COG3321	synthase
GII80_09155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII80_09155	COG2070	2-Nitropropane dioxygenase
GII80_09160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII80_09165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII80_09170	COG3425	synthase
GII80_09175	COG1024	Enoyl-CoA hydratase
GII80_09180	COG1024	Enoyl-CoA hydratase
GII80_09185	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_09185	COG0318	PFAM AMP-dependent synthetase and ligase
GII80_09185	COG0300	oxidoreductase activity
GII80_09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_09185	COG3321	synthase
GII80_09190	COG3321	synthase
GII80_09190	COG4221	oxidoreductase activity
GII80_09190	COG0300	oxidoreductase activity
GII80_09190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII80_09195	COG3321	synthase
GII80_09195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII80_09195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII80_09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_09195	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_09200	COG4221	oxidoreductase activity
GII80_09200	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_09200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_09200	COG3321	synthase
GII80_09205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GII80_09205	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII80_09205	COG3321	synthase
GII80_09205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII80_09210	COG2124	cytochrome p450
GII80_09220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII80_09225	COG1404	Belongs to the peptidase S8 family
GII80_09230	COG4195	phage-related replication protein
GII80_09235	COG1764	response to oxidative stress
GII80_09240	COG2076	Multidrug Resistance protein
GII80_09245	COG2076	Multidrug Resistance protein
GII80_09260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII80_09265	COG1923	regulation of RNA biosynthetic process
GII80_09280	COG1780	Probably involved in ribonucleotide reductase function
GII80_09285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII80_09290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII80_09295	COG4112	unkown
GII80_09300	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII80_09305	COG0464	growth
GII80_09310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII80_09315	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII80_09320	COG0789	Transcriptional regulator
GII80_09325	COG0174	glutamine synthetase
GII80_09345	COG4282	regulation of fungal-type cell wall biogenesis
GII80_09355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII80_09385	COG0135	phosphoribosylanthranilate isomerase activity
GII80_09390	COG2211	Major facilitator Superfamily
GII80_09395	COG3507	Belongs to the glycosyl hydrolase 43 family
GII80_09400	COG1940	carbohydrate kinase activity
GII80_09405	COG2115	Belongs to the xylose isomerase family
GII80_09410	COG1070	Carbohydrate kinase
GII80_09420	COG1525	nuclease
GII80_09425	COG2814	Major facilitator Superfamily
GII80_09430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII80_09440	COG0756	dUTP diphosphatase activity
GII80_09455	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII80_09480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII80_09495	COG3832	glyoxalase III activity
GII80_09505	COG0697	spore germination
GII80_09510	COG0531	amino acid
GII80_09540	COG4195	phage-related replication protein
GII80_09550	COG0346	lactoylglutathione lyase activity
GII80_09555	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII80_09560	COG1388	LysM domain
GII80_09565	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII80_09570	COG4224	UPF0291 protein
GII80_09575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII80_09585	COG3763	UPF0154 protein
GII80_09595	COG0785	Cytochrome C biogenesis protein
GII80_09600	COG2201	protein-glutamate methylesterase activity
GII80_09605	COG4846	Membrane protein involved in cytochrome C biogenesis
GII80_09615	COG0071	Belongs to the small heat shock protein (HSP20) family
GII80_09630	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII80_09635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_09655	COG0824	Thioesterase
GII80_09665	COG4841	protein insertion into membrane
GII80_09670	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII80_09675	COG1832	CoA-binding protein
GII80_09680	COG0187	DNA topoisomerase II activity
GII80_09685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII80_09695	COG1115	amino acid carrier protein
GII80_09700	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GII80_09710	COG5520	Belongs to the glycosyl hydrolase 30 family
GII80_09715	COG3507	Belongs to the glycosyl hydrolase 43 family
GII80_09720	COG2246	polysaccharide biosynthetic process
GII80_09725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII80_09730	COG0586	Pfam SNARE associated Golgi protein
GII80_09735	COG2404	hydrolase activity, acting on ester bonds
GII80_09740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII80_09745	COG1024	Enoyl-CoA hydratase
GII80_09750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII80_09755	COG0511	ligase activity, forming carbon-carbon bonds
GII80_09760	COG0439	Biotin carboxylase
GII80_09765	COG0318	PFAM AMP-dependent synthetase and ligase
GII80_09770	COG1960	acyl-CoA dehydrogenase activity
GII80_09785	COG1649	PFAM Uncharacterised BCR, COG1649
GII80_09795	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII80_09795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_09810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_09815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_09820	COG2027	D-alanyl-D-alanine carboxypeptidase
GII80_09825	COG2017	converts alpha-aldose to the beta-anomer
GII80_09830	COG0534	Mate efflux family protein
GII80_09845	COG0582	viral genome integration into host DNA
GII80_09850	COG0166	Belongs to the GPI family
GII80_09855	COG0405	Gamma-glutamyltransferase
GII80_09860	COG0583	DNA-binding transcription factor activity
GII80_09865	COG0604	alcohol dehydrogenase
GII80_09870	COG0493	'glutamate synthase
GII80_09875	COG0067	glutamate synthase
GII80_09875	COG0070	glutamate synthase
GII80_09875	COG0069	glutamate synthase activity
GII80_09880	COG0583	DNA-binding transcription factor activity
GII80_09885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII80_09890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII80_09900	COG0300	oxidoreductase activity
GII80_09905	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII80_09915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII80_09920	COG2814	Major facilitator Superfamily
GII80_09925	COG1070	Carbohydrate kinase
GII80_09930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII80_09935	COG0243	molybdopterin cofactor binding
GII80_09965	COG5278	phosphoserine phosphatase activity
GII80_09965	COG0840	transmembrane signaling receptor activity
GII80_09970	COG2368	4-hydroxyphenylacetate
GII80_09975	COG4305	rare lipoprotein A
GII80_09980	COG3619	membrane
GII80_09985	COG3866	Pectate lyase
GII80_09990	COG2135	peptidase activity
GII80_10000	COG2140	Oxalate decarboxylase
GII80_10015	COG0456	acetyltransferase
GII80_10035	COG2720	vancomycin resistance protein
GII80_10045	COG3655	Transcriptional regulator
GII80_10050	COG3739	integral membrane protein
GII80_10055	COG0583	DNA-binding transcription factor activity
GII80_10060	COG0697	spore germination
GII80_10070	COG0693	protein deglycase activity
GII80_10075	COG2367	Beta-lactamase
GII80_10100	COG3848	Pyruvate phosphate dikinase
GII80_10100	COG0574	Belongs to the PEP-utilizing enzyme family
GII80_10105	COG0726	polysaccharide deacetylase
GII80_10110	COG2314	TM2 domain
GII80_10115	COG1396	sequence-specific DNA binding
GII80_10130	COG2135	peptidase activity
GII80_10165	COG0457	Tetratricopeptide repeat
GII80_10190	COG5290	Psort location Cytoplasmic, score
GII80_10220	COG4282	regulation of fungal-type cell wall biogenesis
GII80_10225	COG1231	oxidoreductase activity
GII80_10230	COG5434	Belongs to the glycosyl hydrolase 28 family
GII80_10235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII80_10240	COG0662	Cupin 2, conserved barrel domain protein
GII80_10240	COG2207	Transcriptional regulator
GII80_10245	COG0456	acetyltransferase
GII80_10250	COG1309	transcriptional regulator
GII80_10255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII80_10260	COG3708	Transcriptional regulator
GII80_10265	COG2378	regulation of single-species biofilm formation
GII80_10275	COG0640	Transcriptional regulator
GII80_10280	COG0741	lytic transglycosylase activity
GII80_10285	COG2322	membrane
GII80_10300	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII80_10305	COG3239	Fatty acid desaturase
GII80_10310	COG4585	Histidine kinase
GII80_10315	COG2197	response regulator
GII80_10320	COG1388	LysM domain
GII80_10320	COG3584	3D domain protein
GII80_10325	COG0514	ATP-dependent DNA helicase (RecQ)
GII80_10335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII80_10340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII80_10355	COG0071	Belongs to the small heat shock protein (HSP20) family
GII80_10380	COG1012	belongs to the aldehyde dehydrogenase family
GII80_10385	COG1657	PFAM Prenyltransferase squalene oxidase
GII80_10390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII80_10395	COG0733	neurotransmitter:sodium symporter activity
GII80_10400	COG0385	Bile acid
GII80_10405	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII80_10410	COG0567	Dehydrogenase, E1 component
GII80_10415	COG4548	von Willebrand factor, type A
GII80_10420	COG0714	Associated with various cellular activities
GII80_10425	COG2032	superoxide dismutase activity
GII80_10430	COG0791	NLP P60 protein
GII80_10430	COG1388	LysM domain
GII80_10435	COG1819	glycosyl
GII80_10440	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII80_10445	COG0534	Mate efflux family protein
GII80_10450	COG1366	Belongs to the anti-sigma-factor antagonist family
GII80_10455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII80_10460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII80_10470	COG2962	Rard protein
GII80_10485	COG2610	gluconate transmembrane transporter activity
GII80_10490	COG1942	4-Oxalocrotonate Tautomerase
GII80_10495	COG1733	regulation of RNA biosynthetic process
GII80_10500	COG0778	Nitroreductase
GII80_10505	COG0400	carboxylic ester hydrolase activity
GII80_10510	COG0346	lactoylglutathione lyase activity
GII80_10520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII80_10525	COG0793	Belongs to the peptidase S41A family
GII80_10525	COG3409	Peptidoglycan-binding domain 1 protein
GII80_10530	COG2226	methyltransferase
GII80_10540	COG1876	peptidase activity
GII80_10545	COG0813	purine-nucleoside phosphorylase activity
GII80_10560	COG0671	phosphoesterase, PA-phosphatase related
GII80_10580	COG4479	Belongs to the UPF0346 family
GII80_10590	COG1509	lysine 2,3-aminomutase activity
GII80_10595	COG0456	acetyltransferase
GII80_10600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII80_10605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII80_10610	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII80_10615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII80_10630	COG0456	acetyltransferase
GII80_10635	COG0463	Glycosyl transferase, family 2
GII80_10650	COG4641	Protein conserved in bacteria
GII80_10655	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII80_10660	COG1086	Polysaccharide biosynthesis protein
GII80_10670	COG3331	DNA recombination
GII80_10725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII80_10770	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GII80_10775	COG0756	dUTP diphosphatase activity
GII80_10780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_10800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII80_10800	COG1372	Participates in initiation and elongation during chromosome replication
GII80_10805	COG1372	Participates in initiation and elongation during chromosome replication
GII80_10805	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII80_10810	COG1780	Probably involved in ribonucleotide reductase function
GII80_10900	COG0270	DNA (cytosine-5-)-methyltransferase activity
GII80_10910	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GII80_10915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII80_10940	COG3584	3D domain protein
GII80_10945	COG0587	DNA-directed DNA polymerase activity
GII80_10950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII80_10955	COG0358	DNA primase activity
GII80_10960	COG0305	Participates in initiation and elongation during chromosome replication
GII80_10970	COG2887	Belongs to the helicase family. UvrD subfamily
GII80_11000	COG5434	Belongs to the glycosyl hydrolase 28 family
GII80_11000	COG3420	alginic acid biosynthetic process
GII80_11005	COG4195	phage-related replication protein
GII80_11020	COG2135	peptidase activity
GII80_11025	COG1793	dna ligase
GII80_11080	COG4474	Belongs to the UPF0398 family
GII80_11090	COG1388	LysM domain
GII80_11110	COG3645	SOS response
GII80_11110	COG3646	Phage regulatory protein
GII80_11165	COG3655	Transcriptional regulator
GII80_11180	COG0582	viral genome integration into host DNA
GII80_11260	COG3655	Transcriptional regulator
GII80_11300	COG1395	domain, Protein
GII80_11315	COG0776	regulation of translation
GII80_11350	COG4373	Mu-like prophage FluMu protein gp28
GII80_11450	COG0582	viral genome integration into host DNA
GII80_11480	COG1196	nuclear chromosome segregation
GII80_11480	COG0741	lytic transglycosylase activity
GII80_11480	COG0739	heme binding
GII80_11490	COG2433	Pfam Transposase IS66
GII80_11500	COG4632	Exopolysaccharide biosynthesis protein
GII80_11500	COG5434	Belongs to the glycosyl hydrolase 28 family
GII80_11515	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII80_11530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII80_11535	COG0463	Glycosyl transferase, family 2
GII80_11540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_11545	COG2274	protein secretion by the type I secretion system
GII80_11545	COG3271	cysteine-type peptidase activity
GII80_11560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII80_11590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII80_11605	COG5444	nuclease activity
GII80_11610	COG4282	regulation of fungal-type cell wall biogenesis
GII80_11625	COG1525	nuclease
GII80_11635	COG2746	aminoglycoside 3-N-acetyltransferase activity
GII80_11660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII80_11665	COG1086	Polysaccharide biosynthesis protein
GII80_11670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII80_11675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII80_11680	COG1846	Transcriptional regulator
GII80_11685	COG0534	Mate efflux family protein
GII80_11695	COG4698	Protein conserved in bacteria
GII80_11700	COG2755	lipolytic protein G-D-S-L family
GII80_11705	COG1999	signal sequence binding
GII80_11715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII80_11720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII80_11725	COG1272	protein, Hemolysin III
GII80_11730	COG0204	Acyl-transferase
GII80_11735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII80_11740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII80_11745	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII80_11755	COG2136	Putative SAM-dependent methyltransferase
GII80_11755	COG2521	methyltransferase
GII80_11765	COG0129	dihydroxy-acid dehydratase activity
GII80_11770	COG1413	lyase activity
GII80_11775	COG1418	mRNA catabolic process
GII80_11780	COG0386	Belongs to the glutathione peroxidase family
GII80_11785	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII80_11790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII80_11800	COG1278	Cold shock
GII80_11820	COG0328	RNA-DNA hybrid ribonuclease activity
GII80_11825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII80_11830	COG0328	RNA-DNA hybrid ribonuclease activity
GII80_11840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII80_11855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII80_11865	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII80_11870	COG3424	synthase
GII80_11875	COG2233	PERMEase
GII80_11880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII80_11885	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII80_11895	COG0800	Aldolase
GII80_11900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII80_11905	COG1609	Transcriptional regulator
GII80_11910	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII80_11915	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_11920	COG1199	ATP-dependent helicase activity
GII80_11935	COG0116	Belongs to the methyltransferase superfamily
GII80_11950	COG4474	Belongs to the UPF0398 family
GII80_11965	COG3359	exonuclease
GII80_11970	COG1205	dead DEAH box helicase
GII80_11970	COG1111	helicase
GII80_11975	COG2190	(PTS) system
GII80_11980	COG0071	Belongs to the small heat shock protein (HSP20) family
GII80_12015	COG3331	DNA recombination
GII80_12020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII80_12020	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII80_12030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII80_12035	COG3935	DnaD domain protein
GII80_12040	COG0017	Asparaginyl-tRNA synthetase
GII80_12045	COG0436	Aminotransferase
GII80_12050	COG5353	protein conserved in bacteria
GII80_12060	COG1199	ATP-dependent helicase activity
GII80_12060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII80_12065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII80_12070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII80_12075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII80_12080	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII80_12080	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII80_12085	COG0617	tRNA 3'-terminal CCA addition
GII80_12090	COG0438	transferase activity, transferring glycosyl groups
GII80_12095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII80_12100	COG1803	Methylglyoxal synthase
GII80_12105	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII80_12110	COG1694	Mazg nucleotide pyrophosphohydrolase
GII80_12115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII80_12125	COG4347	Protein of unknown function (DUF1405)
GII80_12130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII80_12130	COG2010	Cytochrome c
GII80_12135	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII80_12140	COG0723	plastoquinol--plastocyanin reductase activity
GII80_12150	COG5582	Belongs to the UPF0302 family
GII80_12155	COG0457	Tetratricopeptide repeat
GII80_12160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII80_12165	COG0287	Prephenate dehydrogenase
GII80_12170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GII80_12175	COG0159	tryptophan synthase activity
GII80_12180	COG0133	tryptophan synthase activity
GII80_12185	COG0135	phosphoribosylanthranilate isomerase activity
GII80_12195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII80_12200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII80_12205	COG4401	Chorismate mutase type I
GII80_12210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII80_12215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII80_12220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII80_12225	COG0105	UTP biosynthetic process
GII80_12230	COG0142	geranyltranstransferase activity
GII80_12235	COG2226	methyltransferase
GII80_12240	COG0142	geranyltranstransferase activity
GII80_12250	COG0302	gtp cyclohydrolase
GII80_12255	COG0776	regulation of translation
GII80_12260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII80_12275	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII80_12280	COG1160	GTP binding
GII80_12305	COG1304	FMN binding
GII80_12310	COG0539	negative regulation of cytoplasmic translation
GII80_12315	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII80_12325	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII80_12330	COG2959	enzyme of heme biosynthesis
GII80_12335	COG3409	Peptidoglycan-binding domain 1 protein
GII80_12335	COG3773	Cell wall hydrolase
GII80_12340	COG2339	peptidase activity
GII80_12345	COG0492	ferredoxin-NADP+ reductase activity
GII80_12350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII80_12355	COG4862	establishment of competence for transformation
GII80_12360	COG1408	metallophosphoesterase
GII80_12370	COG1388	LysM domain
GII80_12375	COG1266	CAAX protease self-immunity
GII80_12380	COG0514	ATP-dependent DNA helicase (RecQ)
GII80_12385	COG4955	Helix-turn-helix domain
GII80_12390	COG1141	Ferredoxin
GII80_12395	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII80_12400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII80_12405	COG0710	3-dehydroquinate dehydratase activity
GII80_12415	COG1595	DNA-templated transcription, initiation
GII80_12420	COG5002	protein histidine kinase activity
GII80_12425	COG0745	RESPONSE REGULATOR receiver
GII80_12430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII80_12435	COG1333	cytochrome c biogenesis protein
GII80_12440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_12445	COG1187	pseudouridine synthase activity
GII80_12450	COG0700	Nucleoside recognition
GII80_12455	COG2715	membrane protein required for spore maturation
GII80_12460	COG1686	Belongs to the peptidase S11 family
GII80_12470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII80_12475	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII80_12480	COG1547	Domain of unknown function (DUF309)
GII80_12485	COG0456	acetyltransferase
GII80_12490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII80_12495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII80_12495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII80_12500	COG0307	riboflavin synthase, alpha
GII80_12505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII80_12505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII80_12515	COG0681	Belongs to the peptidase S26 family
GII80_12525	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII80_12540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII80_12545	COG4086	secreted protein
GII80_12550	COG0019	diaminopimelate decarboxylase activity
GII80_12555	COG0697	spore germination
GII80_12570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII80_12590	COG1191	sigma factor activity
GII80_12595	COG2172	sigma factor antagonist activity
GII80_12600	COG1366	Belongs to the anti-sigma-factor antagonist family
GII80_12605	COG1686	Belongs to the peptidase S11 family
GII80_12610	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII80_12615	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII80_12620	COG4974	Belongs to the 'phage' integrase family
GII80_12630	COG0735	belongs to the Fur family
GII80_12635	COG1300	Membrane
GII80_12645	COG0281	malic enzyme
GII80_12650	COG1757	Na H antiporter
GII80_12655	COG1027	Aspartate ammonia-lyase
GII80_12660	COG0252	asparaginase activity
GII80_12665	COG1396	sequence-specific DNA binding
GII80_12670	COG1379	DNA repair
GII80_12675	COG0494	nUDIX hydrolase
GII80_12685	COG0667	Aldo Keto reductase
GII80_12695	COG1073	alpha beta
GII80_12705	COG4918	Iron-sulphur cluster biosynthesis
GII80_12710	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII80_12710	COG0456	acetyltransferase
GII80_12715	COG2329	Antibiotic biosynthesis monooxygenase
GII80_12720	COG0456	acetyltransferase
GII80_12730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII80_12740	COG2211	Major facilitator Superfamily
GII80_12745	COG0346	lactoylglutathione lyase activity
GII80_12750	COG1072	(Pantothenic acid kinase))
GII80_12755	COG3048	D-serine ammonia-lyase activity
GII80_12760	COG0300	oxidoreductase activity
GII80_12765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII80_12770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII80_12775	COG4187	Peptidase family M20/M25/M40
GII80_12780	COG1902	pentaerythritol trinitrate reductase activity
GII80_12785	COG0596	Alpha beta hydrolase
GII80_12795	COG1234	tRNA 3'-trailer cleavage
GII80_12800	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII80_12805	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII80_12810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII80_12820	COG0706	membrane insertase activity
GII80_12825	COG3361	conserved protein (COG2071)
GII80_12830	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII80_12835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII80_12840	COG0346	lactoylglutathione lyase activity
GII80_12850	COG1376	ErfK ybiS ycfS ynhG family protein
GII80_12855	COG4129	membrane
GII80_12860	COG1126	abc transporter atp-binding protein
GII80_12865	COG0765	amino acid transport
GII80_12870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII80_12880	COG1597	lipid kinase activity
GII80_12885	COG2814	Major facilitator Superfamily
GII80_12890	COG0789	Transcriptional regulator
GII80_12890	COG4978	Transcriptional regulator
GII80_12895	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII80_12900	COG0022	dehydrogenase e1 component
GII80_12905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII80_12910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII80_12915	COG3426	butyrate kinase activity
GII80_12920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII80_12925	COG0280	phosphate acetyltransferase
GII80_12930	COG3290	protein histidine kinase activity
GII80_12930	COG3829	transcription factor binding
GII80_12940	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII80_12945	COG2079	MmgE PrpD family protein
GII80_12950	COG0372	Belongs to the citrate synthase family
GII80_12955	COG1960	acyl-CoA dehydrogenase activity
GII80_12960	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII80_12965	COG0183	Belongs to the thiolase family
GII80_12970	COG0584	glycerophosphoryl diester phosphodiesterase
GII80_12975	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII80_12990	COG1902	pentaerythritol trinitrate reductase activity
GII80_12995	COG0745	RESPONSE REGULATOR receiver
GII80_13000	COG0750	zinc metalloprotease
GII80_13005	COG0497	DNA recombination
GII80_13010	COG1438	arginine binding
GII80_13015	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII80_13020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII80_13025	COG0142	geranyltranstransferase activity
GII80_13030	COG1722	exodeoxyribonuclease VII activity
GII80_13035	COG1570	exodeoxyribonuclease VII activity
GII80_13040	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII80_13045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII80_13050	COG1302	Protein conserved in bacteria
GII80_13055	COG0439	Biotin carboxylase
GII80_13060	COG0511	ligase activity, forming carbon-carbon bonds
GII80_13100	COG3854	ATPases associated with a variety of cellular activities
GII80_13110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII80_13115	COG0006	proline dipeptidase activity
GII80_13120	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII80_13130	COG3872	metal-dependent enzyme
GII80_13140	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII80_13145	COG1321	iron dependent repressor
GII80_13150	COG0095	Lipoate-protein ligase
GII80_13155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII80_13160	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII80_13165	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII80_13170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII80_13175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII80_13190	COG1396	sequence-specific DNA binding
GII80_13200	COG0681	Belongs to the peptidase S26 family
GII80_13225	COG4940	Competence protein ComGF
GII80_13235	COG4970	Tfp pilus assembly protein FimT
GII80_13240	COG4537	Required for transformation and DNA binding
GII80_13245	COG1459	type II secretion system
GII80_13250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII80_13255	COG0598	Magnesium transport protein CorA
GII80_13260	COG1253	flavin adenine dinucleotide binding
GII80_13265	COG1366	Belongs to the anti-sigma-factor antagonist family
GII80_13275	COG1393	Belongs to the ArsC family
GII80_13285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII80_13295	COG0011	TIGRFAM Protein of
GII80_13305	COG2866	Carboxypeptidase
GII80_13310	COG1368	sulfuric ester hydrolase activity
GII80_13315	COG1940	carbohydrate kinase activity
GII80_13320	COG4483	Protein conserved in bacteria
GII80_13325	COG0457	Tetratricopeptide repeat
GII80_13325	COG0705	Rhomboid family
GII80_13335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII80_13340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII80_13345	COG0438	transferase activity, transferring glycosyl groups
GII80_13360	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII80_13365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII80_13370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII80_13375	COG0581	inorganic phosphate transmembrane transporter activity
GII80_13380	COG0573	inorganic phosphate transmembrane transporter activity
GII80_13385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII80_13395	COG0477	Major facilitator Superfamily
GII80_13400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII80_13405	COG2839	Protein conserved in bacteria
GII80_13410	COG5521	maltodextrose utilization protein MalA
GII80_13420	COG1388	LysM domain
GII80_13425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII80_13430	COG4709	membrane
GII80_13435	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII80_13440	COG0735	belongs to the Fur family
GII80_13445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII80_13455	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII80_13460	COG0513	Belongs to the DEAD box helicase family
GII80_13470	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII80_13475	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII80_13480	COG2384	SAM-dependent methyltransferase
GII80_13485	COG2010	Cytochrome c
GII80_13490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII80_13495	COG0358	DNA primase activity
GII80_13500	COG1671	Belongs to the UPF0178 family
GII80_13505	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII80_13510	COG0517	IMP dehydrogenase activity
GII80_13515	COG0751	glycine-tRNA ligase activity
GII80_13520	COG0752	glycyl-tRNA synthetase alpha subunit
GII80_13525	COG1381	Involved in DNA repair and RecF pathway recombination
GII80_13535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII80_13540	COG0295	cytidine deaminase activity
GII80_13545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII80_13550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII80_13555	COG1480	7TM receptor with intracellular HD hydrolase
GII80_13560	COG1702	phosphate starvation-inducible protein PhoH
GII80_13565	COG0561	phosphatase activity
GII80_13580	COG4864	UPF0365 protein
GII80_13585	COG1030	water channel activity
GII80_13590	COG1610	YqeY-like protein
GII80_13595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GII80_13600	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII80_13605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII80_13610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII80_13615	COG2264	protein methyltransferase activity
GII80_13620	COG0484	heat shock protein binding
GII80_13625	COG0443	Heat shock 70 kDa protein
GII80_13630	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII80_13635	COG1420	regulation of RNA biosynthetic process
GII80_13640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII80_13645	COG0481	GTPase activity
GII80_13655	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII80_13660	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII80_13665	COG0268	Binds directly to 16S ribosomal RNA
GII80_13670	COG1466	dna polymerase III delta subunit
GII80_13685	COG0658	competence protein
GII80_13685	COG2333	competence protein COMEC
GII80_13690	COG2131	deaminase
GII80_13695	COG1596	polysaccharide export
GII80_13695	COG1555	photosystem II stabilization
GII80_13700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII80_13705	COG2226	methyltransferase
GII80_13710	COG0799	negative regulation of ribosome biogenesis
GII80_13715	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII80_13720	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII80_13725	COG1534	Rna-binding protein
GII80_13730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII80_13735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII80_13740	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII80_13750	COG2755	lipolytic protein G-D-S-L family
GII80_13755	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII80_13755	COG3409	Peptidoglycan-binding domain 1 protein
GII80_13760	COG0398	Pfam SNARE associated Golgi protein
GII80_13765	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GII80_13775	COG3209	COG3209 Rhs family protein
GII80_13785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII80_13790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII80_13795	COG0798	PFAM Bile acid sodium symporter
GII80_13800	COG0346	lactoylglutathione lyase activity
GII80_13805	COG0640	Transcriptional regulator
GII80_13810	COG3403	YqcI/YcgG family
GII80_13815	COG0457	Tetratricopeptide repeat
GII80_13830	COG5444	nuclease activity
GII80_13855	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII80_13855	COG3409	Peptidoglycan-binding domain 1 protein
GII80_13860	COG4824	toxin secretion phage lysis holin
GII80_13890	COG3778	Protein conserved in bacteria
GII80_13895	COG3299	homolog of phage Mu protein gp47
GII80_13900	COG3628	GPW Gp25 family protein
GII80_13910	COG4193	domain, Protein
GII80_13915	COG1652	LysM domain
GII80_13920	COG3953	SLT domain
GII80_13920	COG5280	Phage tail tape measure protein TP901
GII80_13985	COG4653	Phage capsid family
GII80_13990	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII80_14000	COG2369	cell adhesion
GII80_14005	COG5518	Phage portal protein
GII80_14010	COG1783	phage Terminase large subunit
GII80_14015	COG5484	DNA packaging
GII80_14025	COG3677	Transposase
GII80_14040	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GII80_14050	COG1484	DNA-dependent DNA replication
GII80_14055	COG3935	DnaD domain protein
GII80_14060	COG3723	Recombinational DNA repair protein, rece pathway
GII80_14065	COG5377	YqaJ viral recombinase family
GII80_14095	COG1476	TRANSCRIPTIONal
GII80_14100	COG3620	sequence-specific DNA binding
GII80_14110	COG0563	adenylate kinase activity
GII80_14115	COG2856	Zn peptidase
GII80_14140	COG3223	Belongs to the PsiE family
GII80_14145	COG0642	Histidine kinase
GII80_14145	COG5002	protein histidine kinase activity
GII80_14150	COG0745	RESPONSE REGULATOR receiver
GII80_14155	COG2311	Membrane
GII80_14165	COG0454	-acetyltransferase
GII80_14170	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII80_14180	COG0730	response to heat
GII80_14185	COG0425	Belongs to the sulfur carrier protein TusA family
GII80_14190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII80_14190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII80_14200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII80_14200	COG0425	Belongs to the sulfur carrier protein TusA family
GII80_14210	COG2210	Belongs to the sulfur carrier protein TusA family
GII80_14215	COG1937	Protein conserved in bacteria
GII80_14225	COG0662	Cupin 2, conserved barrel domain protein
GII80_14235	COG4978	Transcriptional regulator
GII80_14235	COG0789	Transcriptional regulator
GII80_14240	COG2814	Major facilitator Superfamily
GII80_14245	COG0456	acetyltransferase
GII80_14250	COG1253	flavin adenine dinucleotide binding
GII80_14260	COG0697	spore germination
GII80_14265	COG0583	DNA-binding transcription factor activity
GII80_14270	COG2072	flavoprotein involved in K transport
GII80_14275	COG1230	cation diffusion facilitator family transporter
GII80_14280	COG1942	4-Oxalocrotonate Tautomerase
GII80_14285	COG0583	DNA-binding transcription factor activity
GII80_14295	COG1114	Component of the transport system for branched-chain amino acids
GII80_14300	COG1687	branched-chain amino acid
GII80_14305	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII80_14310	COG1522	sequence-specific DNA binding
GII80_14315	COG2732	(Barnase) inhibitor
GII80_14320	COG2124	cytochrome p450
GII80_14330	COG1335	isochorismatase
GII80_14340	COG2318	DinB family
GII80_14350	COG2070	2-Nitropropane dioxygenase
GII80_14355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII80_14375	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII80_14380	COG1595	DNA-templated transcription, initiation
GII80_14385	COG0667	Aldo Keto reductase
GII80_14390	COG2851	Citrate transporter
GII80_14395	COG0583	DNA-binding transcription factor activity
GII80_14400	COG2828	Protein conserved in bacteria
GII80_14405	COG3409	Peptidoglycan-binding domain 1 protein
GII80_14410	COG5566	PFAM Mor transcription activator
GII80_14415	COG0596	Alpha beta hydrolase
GII80_14420	COG4991	sh3 domain protein
GII80_14425	COG4991	sh3 domain protein
GII80_14435	COG0346	lactoylglutathione lyase activity
GII80_14445	COG5577	PFAM Coat F domain
GII80_14450	COG1063	alcohol dehydrogenase
GII80_14460	COG5577	PFAM Coat F domain
GII80_14465	COG0789	Transcriptional regulator
GII80_14475	COG1064	alcohol dehydrogenase
GII80_14480	COG0693	protein deglycase activity
GII80_14485	COG1621	beta-fructofuranosidase activity
GII80_14490	COG3716	PTS system mannose fructose sorbose family IID component
GII80_14495	COG3715	PTS system
GII80_14500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_14505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII80_14510	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII80_14510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII80_14520	COG1113	amino acid transport
GII80_14525	COG1280	lysine exporter protein (LysE YggA)
GII80_14530	COG1378	Sugar-specific transcriptional regulator TrmB
GII80_14535	COG1595	DNA-templated transcription, initiation
GII80_14545	COG2755	lipolytic protein G-D-S-L family
GII80_14545	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GII80_14555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII80_14555	COG2124	cytochrome p450
GII80_14560	COG1309	transcriptional regulator
GII80_14565	COG2226	methyltransferase
GII80_14580	COG2116	formate transmembrane transporter activity
GII80_14585	COG5609	conserved protein (DUF2294)
GII80_14590	COG3383	formate dehydrogenase (NAD+) activity
GII80_14595	COG2427	Protein of unknown function (DUF1641)
GII80_14605	COG0626	cystathionine gamma-synthase activity
GII80_14610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII80_14615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII80_14620	COG2226	methyltransferase
GII80_14635	COG0768	penicillin binding
GII80_14640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII80_14645	COG0572	uridine kinase
GII80_14665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII80_14670	COG3906	Belongs to the UPF0473 family
GII80_14675	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII80_14680	COG4472	Bacterial protein of unknown function (DUF965)
GII80_14685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII80_14690	COG0628	permease
GII80_14695	COG1126	abc transporter atp-binding protein
GII80_14700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII80_14705	COG0765	amino acid transport
GII80_14710	COG0765	amino acid transport
GII80_14725	COG3881	PFAM PRC-barrel domain
GII80_14730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII80_14735	COG0457	Tetratricopeptide repeat
GII80_14740	COG0482	sulfurtransferase activity
GII80_14745	COG1104	cysteine desulfurase activity
GII80_14750	COG1959	2 iron, 2 sulfur cluster binding
GII80_14755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII80_14760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII80_14770	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII80_14775	COG0124	histidyl-tRNA synthetase
GII80_14785	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII80_14785	COG4991	sh3 domain protein
GII80_14785	COG3103	Sh3 type 3 domain protein
GII80_14790	COG1490	D-aminoacyl-tRNA deacylase activity
GII80_14795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII80_14800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII80_14805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII80_14805	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII80_14810	COG5416	Lipopolysaccharide assembly protein A domain
GII80_14815	COG0490	domain, Protein
GII80_14820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII80_14820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII80_14830	COG2244	polysaccharide biosynthetic process
GII80_14835	COG2323	membrane
GII80_14845	COG1862	Preprotein translocase
GII80_14850	COG0343	queuine tRNA-ribosyltransferase activity
GII80_14855	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII80_14865	COG2255	four-way junction helicase activity
GII80_14870	COG0632	four-way junction helicase activity
GII80_14880	COG2814	Major facilitator Superfamily
GII80_14885	COG0673	inositol 2-dehydrogenase activity
GII80_14890	COG2112	serine threonine protein kinase
GII80_14910	COG1115	amino acid carrier protein
GII80_14915	COG0217	transcriptional regulatory protein
GII80_14925	COG1388	LysM domain
GII80_14930	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII80_14935	COG0157	Belongs to the NadC ModD family
GII80_14940	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII80_14945	COG1104	cysteine desulfurase activity
GII80_14950	COG1827	regulation of RNA biosynthetic process
GII80_14955	COG0077	Prephenate dehydratase
GII80_14960	COG4492	Belongs to the UPF0735 family
GII80_14965	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII80_14970	COG3290	protein histidine kinase activity
GII80_14980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII80_14985	COG2868	ribosomal protein
GII80_14990	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII80_14995	COG1994	Peptidase M50
GII80_15000	COG0739	heme binding
GII80_15005	COG2894	cell division
GII80_15010	COG0850	regulation of cytokinetic process
GII80_15015	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII80_15020	COG1792	Involved in formation and maintenance of cell shape
GII80_15025	COG1077	Cell shape determining protein MreB Mrl
GII80_15030	COG2003	Belongs to the UPF0758 family
GII80_15035	COG0424	maF-like protein
GII80_15045	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII80_15050	COG0285	dihydrofolate synthase activity
GII80_15055	COG0525	valine-tRNA ligase activity
GII80_15065	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII80_15070	COG1388	LysM domain
GII80_15075	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII80_15080	COG0113	porphobilinogen synthase activity
GII80_15085	COG1587	Uroporphyrinogen-III synthase
GII80_15090	COG0181	hydroxymethylbilane synthase activity
GII80_15095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII80_15100	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII80_15110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII80_15115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII80_15120	COG1067	ATP-dependent peptidase activity
GII80_15120	COG0470	DNA polymerase III
GII80_15125	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII80_15130	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII80_15135	COG1477	protein flavinylation
GII80_15135	COG0457	Tetratricopeptide repeat
GII80_15140	COG0066	3-isopropylmalate dehydratase activity
GII80_15145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII80_15150	COG0473	3-isopropylmalate dehydrogenase activity
GII80_15155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII80_15160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII80_15165	COG0440	acetolactate synthase activity
GII80_15170	COG0028	Belongs to the TPP enzyme family
GII80_15180	COG0454	-acetyltransferase
GII80_15185	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII80_15195	COG0622	Phosphoesterase
GII80_15200	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII80_15205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII80_15210	COG5401	PFAM Sporulation and spore germination
GII80_15215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII80_15220	COG1846	Transcriptional regulator
GII80_15225	COG2197	response regulator
GII80_15230	COG0824	Thioesterase
GII80_15235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII80_15240	COG1053	succinate dehydrogenase
GII80_15245	COG2009	succinate dehydrogenase
GII80_15250	COG1719	4-vinyl reductase, 4VR
GII80_15255	COG0527	aspartate kinase activity
GII80_15260	COG0322	excinuclease ABC activity
GII80_15265	COG3118	belongs to the thioredoxin family
GII80_15275	COG3534	alpha-L-arabinofuranosidase
GII80_15280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII80_15285	COG2086	electron transfer activity
GII80_15290	COG1024	Enoyl-CoA hydratase
GII80_15295	COG1309	transcriptional regulator
GII80_15300	COG0318	PFAM AMP-dependent synthetase and ligase
GII80_15305	COG3766	membrane
GII80_15310	COG1193	negative regulation of DNA recombination
GII80_15315	COG1796	DNA polymerase
GII80_15315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII80_15320	COG1286	toxin biosynthetic process
GII80_15325	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII80_15330	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII80_15335	COG0072	phenylalanine-tRNA ligase activity
GII80_15335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII80_15340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII80_15350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII80_15360	COG3835	regulator
GII80_15365	COG0277	FAD linked oxidase domain protein
GII80_15370	COG0247	lactate metabolic process
GII80_15375	COG0346	lactoylglutathione lyase activity
GII80_15385	COG1966	Carbon starvation protein
GII80_15390	COG3534	alpha-L-arabinofuranosidase
GII80_15395	COG0395	ABC-type sugar transport system, permease component
GII80_15400	COG1175	transmembrane transport
GII80_15405	COG1653	transport
GII80_15410	COG0371	Dehydrogenase
GII80_15415	COG0647	UMP catabolic process
GII80_15420	COG0235	Class ii aldolase
GII80_15425	COG1069	ribulokinase activity
GII80_15430	COG2160	L-arabinose isomerase activity
GII80_15435	COG3507	Belongs to the glycosyl hydrolase 43 family
GII80_15440	COG1363	Peptidase, m42
GII80_15450	COG3326	Membrane
GII80_15455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII80_15460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII80_15465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII80_15475	COG1346	cytolysis
GII80_15480	COG1380	Effector of murein hydrolase LrgA
GII80_15485	COG3279	Response regulator of the LytR AlgR family
GII80_15490	COG3275	phosphorelay sensor kinase activity
GII80_15500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII80_15510	COG0398	Pfam SNARE associated Golgi protein
GII80_15515	COG1484	DNA-dependent DNA replication
GII80_15520	COG3611	Membrane attachment protein
GII80_15525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII80_15530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII80_15535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII80_15540	COG1733	regulation of RNA biosynthetic process
GII80_15545	COG2814	Major facilitator Superfamily
GII80_15550	COG0656	L-ascorbic acid biosynthetic process
GII80_15555	COG0237	dephospho-CoA kinase activity
GII80_15560	COG1971	Probably functions as a manganese efflux pump
GII80_15565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII80_15570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII80_15570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII80_15575	COG5002	protein histidine kinase activity
GII80_15580	COG0745	RESPONSE REGULATOR receiver
GII80_15585	COG0039	L-malate dehydrogenase activity
GII80_15590	COG0538	isocitrate dehydrogenase activity
GII80_15595	COG0372	Belongs to the citrate synthase family
GII80_15600	COG2707	UPF0756 membrane protein
GII80_15605	COG0628	permease
GII80_15610	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII80_15615	COG0469	pyruvate kinase activity
GII80_15620	COG0205	6-phosphofructokinase activity
GII80_15625	COG0825	malonyl-CoA metabolic process
GII80_15630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII80_15635	COG0281	malic enzyme
GII80_15640	COG0587	DNA-directed DNA polymerase activity
GII80_15660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII80_15670	COG4109	DRTGG domain
GII80_15675	COG0730	response to heat
GII80_15680	COG1473	amidohydrolase
GII80_15685	COG0196	riboflavin kinase activity
GII80_15690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII80_15695	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII80_15700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII80_15705	COG1126	abc transporter atp-binding protein
GII80_15710	COG0765	amino acid transport
GII80_15715	COG0765	amino acid transport
GII80_15720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII80_15725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII80_15730	COG0454	-acetyltransferase
GII80_15735	COG0583	DNA-binding transcription factor activity
GII80_15740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII80_15745	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_15755	COG0165	Argininosuccinate lyase
GII80_15760	COG0137	argininosuccinate synthase activity
GII80_15765	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII80_15770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII80_15780	COG0827	DNA restriction-modification system
GII80_15785	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII80_15790	COG3874	Sporulation protein YtfJ
GII80_15800	COG1714	RDD family
GII80_15805	COG0616	signal peptide processing
GII80_15810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII80_15815	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII80_15820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII80_15830	COG0301	tRNA thio-modification
GII80_15835	COG1104	cysteine desulfurase activity
GII80_15840	COG1114	Component of the transport system for branched-chain amino acids
GII80_15845	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII80_15850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII80_15855	COG1309	transcriptional regulator
GII80_15860	COG1956	GAF domain-containing protein
GII80_15865	COG2203	Gaf domain
GII80_15865	COG2199	diguanylate cyclase activity
GII80_15875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII80_15880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII80_15885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII80_15890	COG0454	-acetyltransferase
GII80_15895	COG0517	IMP dehydrogenase activity
GII80_15900	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII80_15905	COG1360	Flagellar Motor Protein
GII80_15910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII80_15915	COG1609	Transcriptional regulator
GII80_15920	COG1605	Chorismate mutase
GII80_15920	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII80_15925	COG3118	belongs to the thioredoxin family
GII80_15930	COG4980	gas vesicle protein
GII80_15935	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII80_15940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII80_15945	COG1674	ftsk spoiiie
GII80_15950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII80_15955	COG4848	Belongs to the UPF0354 family
GII80_15960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_15975	COG1363	Peptidase, m42
GII80_15980	COG5584	Small secreted protein
GII80_15985	COG0281	malic enzyme
GII80_15990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII80_15995	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII80_16005	COG0510	thiamine kinase activity
GII80_16010	COG1523	belongs to the glycosyl hydrolase 13 family
GII80_16015	COG1597	lipid kinase activity
GII80_16025	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII80_16030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII80_16035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII80_16040	COG2252	PERMEase
GII80_16045	COG4473	ABC transporter
GII80_16050	COG1131	(ABC) transporter
GII80_16055	COG1349	DNA-binding transcription factor activity
GII80_16060	COG1187	pseudouridine synthase activity
GII80_16065	COG2244	polysaccharide biosynthetic process
GII80_16070	COG2081	HI0933 family
GII80_16075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII80_16085	COG5578	integral membrane protein
GII80_16090	COG0673	inositol 2-dehydrogenase activity
GII80_16095	COG1653	transport
GII80_16100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII80_16105	COG4209	transmembrane transport
GII80_16110	COG2207	Transcriptional regulator
GII80_16115	COG1653	transport
GII80_16120	COG0395	ABC-type sugar transport system, permease component
GII80_16125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII80_16130	COG2124	cytochrome p450
GII80_16135	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII80_16140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GII80_16145	COG0156	8-amino-7-oxononanoate synthase activity
GII80_16150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII80_16155	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GII80_16160	COG1073	alpha beta
GII80_16185	COG1486	melibiose metabolic process
GII80_16190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII80_16195	COG0495	leucyl-tRNA aminoacylation
GII80_16205	COG1366	Belongs to the anti-sigma-factor antagonist family
GII80_16205	COG2202	Pas domain
GII80_16210	COG2814	Major facilitator Superfamily
GII80_16215	COG2433	Pfam Transposase IS66
GII80_16220	COG0577	efflux transmembrane transporter activity
GII80_16225	COG1136	(ABC) transporter
GII80_16230	COG2205	protein histidine kinase activity
GII80_16235	COG0745	RESPONSE REGULATOR receiver
GII80_16240	COG0577	efflux transmembrane transporter activity
GII80_16245	COG1136	(ABC) transporter
GII80_16260	COG1131	(ABC) transporter
GII80_16265	COG1725	Transcriptional regulator
GII80_16280	COG1242	4 iron, 4 sulfur cluster binding
GII80_16285	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII80_16295	COG2267	carboxylic ester hydrolase activity
GII80_16300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII80_16305	COG1113	amino acid transport
GII80_16310	COG0367	asparagine synthase
GII80_16315	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII80_16320	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII80_16330	COG1506	peptidase
GII80_16335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII80_16340	COG1116	anion transmembrane transporter activity
GII80_16345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII80_16350	COG0494	nUDIX hydrolase
GII80_16355	COG4824	toxin secretion phage lysis holin
GII80_16360	COG0783	Belongs to the Dps family
GII80_16375	COG1854	S-ribosylhomocysteine lyase activity
GII80_16380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII80_16385	COG0288	reversible hydration of carbon dioxide
GII80_16390	COG0254	rRNA binding
GII80_16395	COG1271	oxidase subunit
GII80_16400	COG1294	oxidase, subunit
GII80_16410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII80_16415	COG1321	iron dependent repressor
GII80_16415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII80_16420	COG1121	(ABC) transporter
GII80_16425	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII80_16430	COG4948	Mandelate Racemase Muconate Lactonizing
GII80_16435	COG0318	PFAM AMP-dependent synthetase and ligase
GII80_16440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII80_16445	COG0596	Alpha beta hydrolase
GII80_16450	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII80_16455	COG1169	isochorismate synthase
GII80_16460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII80_16465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII80_16470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII80_16475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII80_16480	COG0438	transferase activity, transferring glycosyl groups
GII80_16490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII80_16495	COG0438	transferase activity, transferring glycosyl groups
GII80_16500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII80_16505	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GII80_16510	COG0058	SHG alpha-glucan phosphorylase activity
GII80_16515	COG0297	glycogen (starch) synthase activity
GII80_16520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII80_16525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII80_16530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII80_16655	COG3859	Proton-coupled thiamine transporter YuaJ
GII80_16660	COG1247	-acetyltransferase
GII80_16665	COG2268	Band 7 protein
GII80_16670	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII80_16675	COG2318	DinB family
GII80_16685	COG1454	alcohol dehydrogenase
GII80_16695	COG1510	regulation of RNA biosynthetic process
GII80_16705	COG0569	domain protein
GII80_16710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII80_16715	COG4682	membrane
GII80_16720	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII80_16725	COG0477	Major facilitator Superfamily
GII80_16730	COG5553	Cysteine dioxygenase type I
GII80_16740	COG1968	undecaprenyl-diphosphatase activity
GII80_16745	COG0628	permease
GII80_16750	COG0673	inositol 2-dehydrogenase activity
GII80_16755	COG4806	L-rhamnose isomerase
GII80_16760	COG3254	rhamnose metabolic process
GII80_16765	COG1070	Carbohydrate kinase
GII80_16770	COG1349	DNA-binding transcription factor activity
GII80_16775	COG3347	Dehydrogenase
GII80_16775	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_16780	COG0840	transmembrane signaling receptor activity
GII80_16785	COG0840	transmembrane signaling receptor activity
GII80_16790	COG0840	transmembrane signaling receptor activity
GII80_16795	COG0840	transmembrane signaling receptor activity
GII80_16810	COG0432	Pfam Uncharacterised protein family UPF0047
GII80_16820	COG0366	Alpha amylase catalytic
GII80_16825	COG1253	flavin adenine dinucleotide binding
GII80_16830	COG2738	Putative neutral zinc metallopeptidase
GII80_16845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII80_16860	COG0166	Belongs to the GPI family
GII80_16865	COG1979	alcohol dehydrogenase
GII80_16870	COG1979	alcohol dehydrogenase
GII80_16875	COG2155	Conserved Protein
GII80_16880	COG1098	S1 RNA binding domain
GII80_16885	COG0436	Aminotransferase
GII80_16890	COG1522	sequence-specific DNA binding
GII80_16895	COG2267	carboxylic ester hydrolase activity
GII80_16905	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII80_16910	COG2205	protein histidine kinase activity
GII80_16920	COG5018	Exonuclease
GII80_16930	COG2814	Major facilitator Superfamily
GII80_16935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII80_16940	COG3011	Protein conserved in bacteria
GII80_16950	COG3290	protein histidine kinase activity
GII80_16955	COG4565	transcriptional regulatory protein
GII80_16980	COG3493	citrate carrier protein
GII80_16990	COG2111	Na H antiporter
GII80_16990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII80_16995	COG2111	Na H antiporter
GII80_17000	COG1006	Multisubunit Na H antiporter MnhC subunit
GII80_17005	COG0651	ATP synthesis coupled electron transport
GII80_17010	COG1863	multisubunit Na H antiporter MnhE subunit
GII80_17015	COG2212	antiporter activity
GII80_17020	COG1320	monovalent cation:proton antiporter activity
GII80_17025	COG2050	protein possibly involved in aromatic compounds catabolism
GII80_17030	COG2197	response regulator
GII80_17035	COG4585	Histidine kinase
GII80_17045	COG0142	geranyltranstransferase activity
GII80_17065	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII80_17070	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII80_17075	COG1335	isochorismatase
GII80_17080	COG5506	Protein of unknown function (DUF1694)
GII80_17095	COG0628	permease
GII80_17110	COG1418	mRNA catabolic process
GII80_17115	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_17125	COG1511	domain protein
GII80_17130	COG0433	COG0433 Predicted ATPase
GII80_17130	COG1674	ftsk spoiiie
GII80_17135	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII80_17140	COG5417	Belongs to the EsaB family
GII80_17145	COG4842	Belongs to the WXG100 family
GII80_17150	COG2508	Transcriptional regulator
GII80_17150	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII80_17155	COG0686	Belongs to the AlaDH PNT family
GII80_17160	COG5634	Uncharacterized conserved protein (DUF2278)
GII80_17165	COG3251	PFAM MbtH domain protein
GII80_17170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_17175	COG3433	isochorismatase activity
GII80_17175	COG1535	isochorismatase
GII80_17180	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII80_17185	COG1169	isochorismate synthase
GII80_17190	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_17195	COG2819	hydrolase of the alpha beta superfamily
GII80_17200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII80_17205	COG1268	BioY protein
GII80_17210	COG2056	Na+-H+ antiporter family
GII80_17215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII80_17220	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII80_17225	COG3584	3D domain protein
GII80_17240	COG1252	NADH dehydrogenase
GII80_17245	COG0492	ferredoxin-NADP+ reductase activity
GII80_17255	COG0516	GMP reductase activity
GII80_17260	COG2808	Putative FMN-binding domain
GII80_17265	COG0456	acetyltransferase
GII80_17270	COG0316	Belongs to the HesB IscA family
GII80_17275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII80_17280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII80_17285	COG4844	belongs to the
GII80_17290	COG1252	NADH dehydrogenase
GII80_17295	COG4837	Protein of unknown function (DUF1462)
GII80_17300	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII80_17305	COG4946	Tricorn protease homolog
GII80_17305	COG1506	peptidase
GII80_17305	COG0823	Involved in the tonB-independent uptake of proteins
GII80_17310	COG0083	homoserine kinase activity
GII80_17315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII80_17320	COG0460	homoserine dehydrogenase
GII80_17325	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII80_17330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII80_17335	COG0647	UMP catabolic process
GII80_17340	COG2445	Protein of unknown function DUF86
GII80_17345	COG4470	Protein conserved in bacteria
GII80_17355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII80_17360	COG0739	heme binding
GII80_17370	COG3377	Domain of unknown function (DUF1805)
GII80_17375	COG0737	Belongs to the 5'-nucleotidase family
GII80_17380	COG0730	response to heat
GII80_17385	COG1801	Protein of unknown function DUF72
GII80_17395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII80_17400	COG2508	Transcriptional regulator
GII80_17405	COG2233	PERMEase
GII80_17410	COG2233	PERMEase
GII80_17415	COG3195	allantoin biosynthetic process
GII80_17415	COG3648	Uricase
GII80_17420	COG2351	hydroxyisourate hydrolase activity
GII80_17430	COG2080	2 iron, 2 sulfur cluster binding
GII80_17435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII80_17440	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII80_17445	COG2068	MobA-Related Protein
GII80_17450	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII80_17455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII80_17460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII80_17470	COG2356	endonuclease I
GII80_17475	COG3842	ATPase activity
GII80_17480	COG2188	Transcriptional regulator
GII80_17485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII80_17490	COG0395	ABC-type sugar transport system, permease component
GII80_17495	COG1175	transmembrane transport
GII80_17500	COG1653	transport
GII80_17505	COG2222	sugar isomerase
GII80_17510	COG0322	excinuclease ABC activity
GII80_17515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII80_17530	COG0346	lactoylglutathione lyase activity
GII80_17535	COG0640	Transcriptional regulator
GII80_17540	COG0719	Fe-S assembly protein
GII80_17545	COG0822	iron-sulfur transferase activity
GII80_17550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII80_17555	COG0719	Fe-S assembly protein
GII80_17560	COG0396	ATPase activity
GII80_17570	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII80_17575	COG1464	Belongs to the NlpA lipoprotein family
GII80_17580	COG2011	ABC-type metal ion transport system permease component
GII80_17585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII80_17595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII80_17600	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII80_17610	COG0509	glycine decarboxylation via glycine cleavage system
GII80_17615	COG1393	Belongs to the ArsC family
GII80_17620	COG1960	acyl-CoA dehydrogenase activity
GII80_17625	COG0183	Belongs to the thiolase family
GII80_17630	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII80_17630	COG1024	Enoyl-CoA hydratase
GII80_17640	COG0506	proline dehydrogenase activity
GII80_17650	COG5577	PFAM Coat F domain
GII80_17655	COG1846	Transcriptional regulator
GII80_17660	COG0477	Major facilitator Superfamily
GII80_17665	COG1942	4-Oxalocrotonate Tautomerase
GII80_17675	COG0583	DNA-binding transcription factor activity
GII80_17685	COG1120	ATPase activity
GII80_17700	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_17705	COG0783	Belongs to the Dps family
GII80_17710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII80_17715	COG0745	RESPONSE REGULATOR receiver
GII80_17720	COG2770	Histidine kinase
GII80_17720	COG2205	protein histidine kinase activity
GII80_17730	COG1309	transcriptional regulator
GII80_17735	COG0114	fumarate hydratase activity
GII80_17745	COG0697	spore germination
GII80_17750	COG0814	amino acid
GII80_17760	COG2197	response regulator
GII80_17765	COG4585	Histidine kinase
GII80_17770	COG4758	membrane
GII80_17775	COG3595	metallopeptidase activity
GII80_17780	COG1842	Phage shock protein A
GII80_17785	COG4758	membrane
GII80_17790	COG2814	Major facilitator Superfamily
GII80_17795	COG2096	Adenosyltransferase
GII80_17800	COG1120	ATPase activity
GII80_17805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII80_17810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII80_17815	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_17820	COG3386	PFAM SMP-30 Gluconolaconase
GII80_17825	COG2205	protein histidine kinase activity
GII80_17830	COG0745	RESPONSE REGULATOR receiver
GII80_17840	COG1191	sigma factor activity
GII80_17850	COG2140	Oxalate decarboxylase
GII80_17860	COG0577	efflux transmembrane transporter activity
GII80_17865	COG1136	(ABC) transporter
GII80_17870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII80_17875	COG1120	ATPase activity
GII80_17880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII80_17885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII80_17890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII80_17895	COG0531	amino acid
GII80_17905	COG1988	membrane-bound metal-dependent
GII80_17910	COG1368	sulfuric ester hydrolase activity
GII80_17915	COG1910	domain protein
GII80_17920	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII80_17925	COG4149	molybdate abc transporter
GII80_17930	COG0656	L-ascorbic acid biosynthetic process
GII80_17940	COG0025	NhaP-type Na H and K H
GII80_17945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII80_17950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII80_17955	COG3973	AAA domain
GII80_17960	COG2860	membrane
GII80_17965	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII80_17970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII80_17975	COG2217	Heavy metal translocating P-type atpase
GII80_17980	COG2217	Heavy metal translocating P-type atpase
GII80_17985	COG2608	mercury ion transmembrane transporter activity
GII80_17990	COG1937	Protein conserved in bacteria
GII80_17995	COG0673	inositol 2-dehydrogenase activity
GII80_18000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII80_18005	COG1289	transmembrane transporter activity
GII80_18015	COG2076	Multidrug Resistance protein
GII80_18020	COG1309	transcriptional regulator
GII80_18025	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_18035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII80_18040	COG0557	exoribonuclease II activity
GII80_18045	COG1647	Serine aminopeptidase, S33
GII80_18050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII80_18055	COG0596	Alpha beta hydrolase
GII80_18060	COG1476	TRANSCRIPTIONal
GII80_18065	COG1396	sequence-specific DNA binding
GII80_18070	COG1396	sequence-specific DNA binding
GII80_18075	COG1733	regulation of RNA biosynthetic process
GII80_18080	COG0840	transmembrane signaling receptor activity
GII80_18085	COG1174	glycine betaine transport
GII80_18090	COG1732	Glycine betaine
GII80_18095	COG1174	glycine betaine transport
GII80_18100	COG0517	IMP dehydrogenase activity
GII80_18100	COG1125	glycine betaine transport
GII80_18105	COG1510	regulation of RNA biosynthetic process
GII80_18125	COG5658	integral membrane protein
GII80_18130	COG0640	Transcriptional regulator
GII80_18135	COG1174	glycine betaine transport
GII80_18140	COG1732	Glycine betaine
GII80_18145	COG1174	glycine betaine transport
GII80_18150	COG1125	glycine betaine transport
GII80_18150	COG0517	IMP dehydrogenase activity
GII80_18155	COG1510	regulation of RNA biosynthetic process
GII80_18160	COG2095	MarC family integral membrane protein
GII80_18170	COG3064	Membrane
GII80_18175	COG4640	response to antibiotic
GII80_18180	COG0456	acetyltransferase
GII80_18185	COG0148	phosphopyruvate hydratase activity
GII80_18190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII80_18195	COG0149	triose-phosphate isomerase activity
GII80_18200	COG0126	phosphoglycerate kinase activity
GII80_18205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII80_18210	COG2390	Transcriptional regulator
GII80_18215	COG2814	Major facilitator Superfamily
GII80_18220	COG1609	Transcriptional regulator
GII80_18225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII80_18230	COG0583	DNA-binding transcription factor activity
GII80_18235	COG0697	spore germination
GII80_18240	COG1113	amino acid transport
GII80_18245	COG3858	chitin binding
GII80_18250	COG1556	Lactate utilization protein
GII80_18255	COG1139	Iron-sulfur cluster binding protein
GII80_18260	COG0247	lactate metabolic process
GII80_18265	COG2197	response regulator
GII80_18270	COG4585	Histidine kinase
GII80_18275	COG0842	Transport permease protein
GII80_18280	COG1131	(ABC) transporter
GII80_18285	COG0596	Alpha beta hydrolase
GII80_18290	COG2208	phosphoserine phosphatase activity
GII80_18295	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII80_18300	COG1874	Beta-galactosidase
GII80_18305	COG3833	ABC-type maltose transport systems, permease component
GII80_18310	COG1175	transmembrane transport
GII80_18315	COG2182	Extracellular solute-binding protein
GII80_18320	COG1609	Transcriptional regulator
GII80_18325	COG2186	Transcriptional regulator
GII80_18330	COG1620	l-lactate permease
GII80_18335	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII80_18345	COG5039	Polysaccharide pyruvyl transferase
GII80_18350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII80_18355	COG0110	maltose O-acetyltransferase activity
GII80_18360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII80_18365	COG2244	polysaccharide biosynthetic process
GII80_18370	COG1216	Glycosyl transferase, family 2
GII80_18375	COG5039	Polysaccharide pyruvyl transferase
GII80_18380	COG1216	Glycosyl transferase, family 2
GII80_18390	COG0438	transferase activity, transferring glycosyl groups
GII80_18395	COG1215	transferase activity, transferring glycosyl groups
GII80_18400	COG0438	transferase activity, transferring glycosyl groups
GII80_18405	COG1086	Polysaccharide biosynthesis protein
GII80_18410	COG0489	protein tyrosine kinase activity
GII80_18415	COG3944	biosynthesis protein
GII80_18420	COG1396	sequence-specific DNA binding
GII80_18425	COG2272	Belongs to the type-B carboxylesterase lipase family
GII80_18435	COG3479	Phenolic acid decarboxylase
GII80_18445	COG1794	racemase activity, acting on amino acids and derivatives
GII80_18450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII80_18455	COG1621	beta-fructofuranosidase activity
GII80_18460	COG1621	beta-fructofuranosidase activity
GII80_18465	COG0531	amino acid
GII80_18470	COG1309	transcriptional regulator
GII80_18475	COG2076	Multidrug Resistance protein
GII80_18480	COG2076	Multidrug Resistance protein
GII80_18490	COG0277	FAD linked oxidase domain protein
GII80_18495	COG3621	Patatin-like phospholipase
GII80_18505	COG0740	serine-type endopeptidase activity
GII80_18515	COG0366	Alpha amylase catalytic
GII80_18520	COG1554	hydrolase, family 65, central catalytic
GII80_18525	COG5521	maltodextrose utilization protein MalA
GII80_18530	COG3833	ABC-type maltose transport systems, permease component
GII80_18535	COG1175	transmembrane transport
GII80_18540	COG2182	Extracellular solute-binding protein
GII80_18545	COG0366	Alpha amylase catalytic
GII80_18550	COG1609	Transcriptional regulator
GII80_18555	COG1611	Belongs to the LOG family
GII80_18560	COG1694	Mazg nucleotide pyrophosphohydrolase
GII80_18565	COG0659	secondary active sulfate transmembrane transporter activity
GII80_18570	COG0288	reversible hydration of carbon dioxide
GII80_18575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII80_18580	COG0577	efflux transmembrane transporter activity
GII80_18585	COG1136	(ABC) transporter
GII80_18590	COG5002	protein histidine kinase activity
GII80_18595	COG0745	RESPONSE REGULATOR receiver
GII80_18605	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII80_18610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII80_18615	COG1481	regulation of sporulation
GII80_18620	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII80_18625	COG1660	Displays ATPase and GTPase activities
GII80_18630	COG1051	belongs to the nudix hydrolase family
GII80_18635	COG0492	ferredoxin-NADP+ reductase activity
GII80_18640	COG3883	PFAM NLP P60 protein
GII80_18640	COG0791	NLP P60 protein
GII80_18645	COG0457	Tetratricopeptide repeat
GII80_18650	COG1132	(ABC) transporter
GII80_18670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII80_18670	COG0140	phosphoribosyl-ATP diphosphatase activity
GII80_18675	COG0107	imidazoleglycerol-phosphate synthase activity
GII80_18680	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII80_18685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII80_18690	COG0131	Imidazoleglycerol-phosphate dehydratase
GII80_18695	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII80_18700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII80_18705	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII80_18710	COG4990	cell redox homeostasis
GII80_18715	COG5297	Belongs to the glycosyl hydrolase family 6
GII80_18720	COG0110	maltose O-acetyltransferase activity
GII80_18725	COG0546	phosphoglycolate phosphatase activity
GII80_18730	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII80_18735	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII80_18740	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII80_18745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII80_18750	COG0363	glucosamine-6-phosphate deaminase activity
GII80_18760	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII80_18765	COG1846	Transcriptional regulator
GII80_18770	COG2124	cytochrome p450
GII80_18780	COG1846	Transcriptional regulator
GII80_18785	COG2814	Major facilitator Superfamily
GII80_18790	COG1950	PFAM Membrane protein of
GII80_18795	COG1983	PspC domain protein
GII80_18800	COG3595	metallopeptidase activity
GII80_18820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII80_18825	COG0556	nucleotide-excision repair
GII80_18830	COG4897	Protein conserved in bacteria
GII80_18835	COG0574	Belongs to the PEP-utilizing enzyme family
GII80_18835	COG3848	Pyruvate phosphate dikinase
GII80_18840	COG1309	transcriptional regulator
GII80_18845	COG2814	Major facilitator Superfamily
GII80_18850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII80_18860	COG3409	Peptidoglycan-binding domain 1 protein
GII80_18860	COG0793	Belongs to the peptidase S41A family
GII80_18865	COG2177	Part of the ABC transporter FtsEX involved in
GII80_18870	COG2884	Cell division ATP-binding protein ftsE
GII80_18875	COG2010	Cytochrome c
GII80_18880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII80_18890	COG0653	protein targeting
GII80_18895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII80_18910	COG1516	flagellar protein fliS
GII80_18915	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII80_18920	COG1334	flagellar protein FlaG
GII80_18925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII80_18930	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII80_18935	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII80_18945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII80_18950	COG4786	Flagellar basal body rod
GII80_18950	COG1256	bacterial-type flagellum assembly
GII80_18955	COG3418	PFAM FlgN family protein
GII80_18960	COG2747	anti-sigma28 factor FlgM
GII80_18970	COG1040	competence protein
GII80_18980	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII80_18985	COG1307	EDD domain protein, DegV family
GII80_18990	COG2197	response regulator
GII80_18995	COG4585	Histidine kinase
GII80_19000	COG1739	Uncharacterized protein family UPF0029
GII80_19005	COG1316	TRANSCRIPTIONal
GII80_19010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII80_19015	COG0438	transferase activity, transferring glycosyl groups
GII80_19020	COG1215	transferase activity, transferring glycosyl groups
GII80_19025	COG3206	protein involved in exopolysaccharide biosynthesis
GII80_19030	COG3307	-O-antigen
GII80_19035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII80_19040	COG0297	glycogen (starch) synthase activity
GII80_19040	COG0438	transferase activity, transferring glycosyl groups
GII80_19045	COG2244	polysaccharide biosynthetic process
GII80_19055	COG2247	cell wall binding repeat
GII80_19055	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII80_19060	COG2385	sporulation resulting in formation of a cellular spore
GII80_19060	COG2247	cell wall binding repeat
GII80_19070	COG1316	TRANSCRIPTIONal
GII80_19075	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII80_19080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII80_19090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII80_19090	COG1215	transferase activity, transferring glycosyl groups
GII80_19095	COG0463	Glycosyl transferase, family 2
GII80_19105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII80_19115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII80_19120	COG1134	teichoic acid transport
GII80_19125	COG1682	transport, permease protein
GII80_19130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII80_19135	COG0438	transferase activity, transferring glycosyl groups
GII80_19140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GII80_19145	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GII80_19150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII80_19160	COG4193	domain, Protein
GII80_19165	COG1482	cell wall glycoprotein biosynthetic process
GII80_19170	COG0697	spore germination
GII80_19175	COG0814	amino acid
GII80_19185	COG2814	Major facilitator Superfamily
GII80_19190	COG1316	TRANSCRIPTIONal
GII80_19195	COG0561	phosphatase activity
GII80_19200	COG0791	NLP P60 protein
GII80_19210	COG2843	Capsule synthesis protein
GII80_19220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII80_19225	COG1609	Transcriptional regulator
GII80_19230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII80_19235	COG1869	D-ribose catabolic process
GII80_19240	COG1129	ABC transporter
GII80_19245	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII80_19250	COG1879	ABC-type sugar transport system periplasmic component
GII80_19255	COG3103	Sh3 type 3 domain protein
GII80_19265	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII80_19270	COG3527	Alpha-acetolactate decarboxylase
GII80_19275	COG0028	Belongs to the TPP enzyme family
GII80_19280	COG0583	DNA-binding transcription factor activity
GII80_19285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII80_19300	COG5337	Spore coat protein CotH
GII80_19310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII80_19320	COG0405	Gamma-glutamyltransferase
GII80_19325	COG1522	sequence-specific DNA binding
GII80_19330	COG2059	Chromate
GII80_19335	COG2059	Chromate
GII80_19345	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII80_19350	COG0583	DNA-binding transcription factor activity
GII80_19355	COG1515	deoxyribonuclease V activity
GII80_19360	COG2849	repeat protein
GII80_19365	COG5444	nuclease activity
GII80_19385	COG3878	Protein conserved in bacteria
GII80_19390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII80_19395	COG4464	protein tyrosine phosphatase activity
GII80_19400	COG0489	protein tyrosine kinase activity
GII80_19405	COG3944	biosynthesis protein
GII80_19415	COG4715	Zinc finger, swim domain protein
GII80_19420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII80_19425	COG0561	phosphatase activity
GII80_19430	COG1349	DNA-binding transcription factor activity
GII80_19435	COG0629	single-stranded DNA binding
GII80_19450	COG3764	Sortase (surface protein transpeptidase)
GII80_19460	COG2972	Histidine kinase
GII80_19460	COG0745	RESPONSE REGULATOR receiver
GII80_19465	COG1970	mechanosensitive ion channel activity
GII80_19470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII80_19475	COG0457	Tetratricopeptide repeat
GII80_19480	COG4786	Flagellar basal body rod
GII80_19485	COG4786	Flagellar basal body rod
GII80_19490	COG1077	Cell shape determining protein MreB Mrl
GII80_19495	COG1609	Transcriptional regulator
GII80_19505	COG1846	Transcriptional regulator
GII80_19510	COG2814	Major facilitator Superfamily
GII80_19515	COG3420	alginic acid biosynthetic process
GII80_19520	COG1953	Uracil, thiamine, allantoin
GII80_19525	COG0477	Major facilitator Superfamily
GII80_19530	COG1335	isochorismatase
GII80_19540	COG0004	ammonium transporteR
GII80_19545	COG0347	Belongs to the P(II) protein family
GII80_19550	COG0671	phosphoesterase, PA-phosphatase related
GII80_19560	COG0739	heme binding
GII80_19565	COG1247	-acetyltransferase
GII80_19585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII80_19590	COG0789	Transcriptional regulator
GII80_19600	COG2910	NAD(P)H-binding
GII80_19605	COG1959	2 iron, 2 sulfur cluster binding
GII80_19610	COG0804	urea catabolic process
GII80_19615	COG0832	Belongs to the urease beta subunit family
GII80_19620	COG0831	urea catabolic process
GII80_19635	COG3237	CsbD-like
GII80_19640	COG1994	Peptidase M50
GII80_19645	COG0457	Tetratricopeptide repeat
GII80_19650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII80_19655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII80_19665	COG2304	oxidoreductase activity
GII80_19675	COG2304	oxidoreductase activity
GII80_19680	COG2385	sporulation resulting in formation of a cellular spore
GII80_19685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII80_19695	COG4836	Membrane
GII80_19705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII80_19710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII80_19715	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII80_19720	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII80_19725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII80_19730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII80_19735	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII80_19740	COG0356	it plays a direct role in the translocation of protons across the membrane
GII80_19750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII80_19755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII80_19760	COG4475	Protein of unknown function (DUF436)
GII80_19765	COG0698	ribose 5-phosphate isomerase
GII80_19770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII80_19775	COG1971	Probably functions as a manganese efflux pump
GII80_19780	COG0009	L-threonylcarbamoyladenylate synthase
GII80_19785	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII80_19805	COG2890	protein-(glutamine-N5) methyltransferase activity
GII80_19810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII80_19815	COG0346	lactoylglutathione lyase activity
GII80_19820	COG0789	Transcriptional regulator
GII80_19825	COG0679	Auxin Efflux Carrier
GII80_19830	COG0281	malic enzyme
GII80_19835	COG1435	thymidine kinase activity
GII80_19840	COG0254	rRNA binding
GII80_19845	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII80_19855	COG1494	fructose-1,6-bisphosphatase
GII80_19860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII80_19865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII80_19870	COG0191	fructose-bisphosphate aldolase activity
GII80_19875	COG2204	response regulator
GII80_19880	COG4821	SIS domain
GII80_19885	COG0504	CTP synthase activity
GII80_19890	COG3343	RNA polymerase activity
GII80_19895	COG1960	acyl-CoA dehydrogenase activity
GII80_19900	COG0247	lactate metabolic process
GII80_19900	COG2181	nitrate reductase activity
GII80_19905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII80_19910	COG4294	response to UV
GII80_19920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII80_19935	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII80_19940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII80_19950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII80_19955	COG2223	nitrite transmembrane transporter activity
GII80_19960	COG0018	arginyl-trna synthetase
GII80_19965	COG4506	Protein conserved in bacteria
GII80_19980	COG0535	radical SAM domain protein
GII80_19990	COG1131	(ABC) transporter
GII80_19995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII80_20000	COG0612	Peptidase, M16
GII80_20005	COG0612	Peptidase, M16
GII80_20015	COG3391	amine dehydrogenase activity
GII80_20020	COG3391	amine dehydrogenase activity
GII80_20030	COG0457	Tetratricopeptide repeat
GII80_20040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII80_20045	COG0010	Belongs to the arginase family
GII80_20050	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII80_20055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII80_20065	COG1994	Peptidase M50
GII80_20070	COG1942	4-Oxalocrotonate Tautomerase
GII80_20075	COG1846	Transcriptional regulator
GII80_20080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII80_20085	COG0477	Major facilitator Superfamily
GII80_20090	COG1959	2 iron, 2 sulfur cluster binding
GII80_20095	COG3465	dGTPase activity
GII80_20100	COG1078	dGTPase activity
GII80_20105	COG4844	belongs to the
GII80_20115	COG0697	spore germination
GII80_20120	COG0095	Lipoate-protein ligase
GII80_20125	COG0583	DNA-binding transcription factor activity
GII80_20130	COG0280	phosphate acetyltransferase
GII80_20140	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_20145	COG0436	Aminotransferase
GII80_20150	COG2814	Major facilitator Superfamily
GII80_20155	COG0151	Belongs to the GarS family
GII80_20160	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_20165	COG1917	Cupin 2, conserved barrel domain protein
GII80_20170	COG0077	Prephenate dehydratase
GII80_20175	COG2814	Major facilitator Superfamily
GII80_20180	COG0833	amino acid
GII80_20185	COG4187	Peptidase family M20/M25/M40
GII80_20190	COG1012	belongs to the aldehyde dehydrogenase family
GII80_20195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII80_20205	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII80_20210	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII80_20215	COG1088	dTDP-glucose 4,6-dehydratase activity
GII80_20220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII80_20225	COG3980	spore coat polysaccharide biosynthesis protein
GII80_20230	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII80_20235	COG2089	acid synthase
GII80_20240	COG0456	acetyltransferase
GII80_20245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII80_20250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII80_20255	COG0463	Glycosyl transferase, family 2
GII80_20265	COG2363	Small membrane protein
GII80_20270	COG2233	PERMEase
GII80_20280	COG1012	belongs to the aldehyde dehydrogenase family
GII80_20285	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII80_20290	COG1216	Glycosyl transferase, family 2
GII80_20305	COG1695	Transcriptional regulator
GII80_20310	COG0351	phosphomethylpyrimidine kinase
GII80_20320	COG1621	beta-fructofuranosidase activity
GII80_20325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_20325	COG1263	PTS System
GII80_20330	COG2116	formate transmembrane transporter activity
GII80_20335	COG3711	transcriptional antiterminator
GII80_20345	COG1404	Belongs to the peptidase S8 family
GII80_20350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII80_20355	COG0778	Nitroreductase
GII80_20360	COG0772	Belongs to the SEDS family
GII80_20370	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII80_20375	COG1845	cytochrome c oxidase, subunit III
GII80_20380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII80_20385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII80_20390	COG2261	transglycosylase associated protein
GII80_20395	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII80_20400	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII80_20405	COG2246	polysaccharide biosynthetic process
GII80_20410	COG1309	transcriptional regulator
GII80_20420	COG3162	membrane
GII80_20425	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII80_20430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII80_20435	COG2837	iron assimilation
GII80_20440	COG2822	iron ion transport
GII80_20445	COG0672	)-iron permease
GII80_20450	COG0352	thiamine-phosphate diphosphorylase activity
GII80_20455	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII80_20460	COG0583	DNA-binding transcription factor activity
GII80_20465	COG1380	Effector of murein hydrolase LrgA
GII80_20470	COG1346	cytolysis
GII80_20475	COG2814	Major facilitator Superfamily
GII80_20480	COG4895	conserved protein (DUF2196)
GII80_20485	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII80_20490	COG0346	lactoylglutathione lyase activity
GII80_20500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII80_20505	COG1404	Belongs to the peptidase S8 family
GII80_20510	COG1263	PTS System
GII80_20510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_20515	COG3711	transcriptional antiterminator
GII80_20520	COG1442	glycosyl transferase family 8
GII80_20525	COG5522	Integral membrane protein (intg_mem_TP0381)
GII80_20530	COG1846	Transcriptional regulator
GII80_20535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII80_20540	COG2234	aminopeptidase activity
GII80_20545	COG2357	RelA SpoT domain protein
GII80_20550	COG1575	Belongs to the MenA family. Type 1 subfamily
GII80_20565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII80_20570	COG1696	Membrane protein involved in D-alanine export
GII80_20575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII80_20580	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII80_20585	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII80_20590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII80_20595	COG1486	melibiose metabolic process
GII80_20600	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII80_20605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII80_20610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII80_20615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII80_20615	COG3711	transcriptional antiterminator
GII80_20625	COG2094	Belongs to the DNA glycosylase MPG family
GII80_20630	COG0753	catalase activity
GII80_20635	COG2814	Major facilitator Superfamily
GII80_20640	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII80_20645	COG1131	(ABC) transporter
GII80_20665	COG1595	DNA-templated transcription, initiation
GII80_20670	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII80_20675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII80_20680	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII80_20685	COG4988	ABC transporter
GII80_20690	COG1294	oxidase, subunit
GII80_20695	COG1271	oxidase subunit
GII80_20700	COG3493	citrate carrier protein
GII80_20705	COG0501	Belongs to the peptidase M48B family
GII80_20715	COG0726	polysaccharide deacetylase
GII80_20720	COG3842	ATPase activity
GII80_20725	COG2508	Transcriptional regulator
GII80_20730	COG1012	belongs to the aldehyde dehydrogenase family
GII80_20735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII80_20745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII80_20750	COG1881	PFAM PEBP family protein
GII80_20755	COG0583	DNA-binding transcription factor activity
GII80_20765	COG4585	Histidine kinase
GII80_20770	COG2197	response regulator
GII80_20775	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII80_20785	COG4894	glucomannan catabolic process
GII80_20790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII80_20795	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII80_20800	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_20805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII80_20810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII80_20815	COG2610	gluconate transmembrane transporter activity
GII80_20820	COG0500	methyltransferase
GII80_20825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII80_20840	COG0693	protein deglycase activity
GII80_20840	COG0753	catalase activity
GII80_20845	COG2851	Citrate transporter
GII80_20850	COG2273	Hydrolase Family 16
GII80_20855	COG3711	transcriptional antiterminator
GII80_20865	COG2270	Major facilitator Superfamily
GII80_20870	COG0513	Belongs to the DEAD box helicase family
GII80_20875	COG3401	FG-GAP repeat protein
GII80_20875	COG2755	lipolytic protein G-D-S-L family
GII80_20935	COG3209	COG3209 Rhs family protein
GII80_20940	COG0697	spore germination
GII80_20945	COG0589	response to stress
GII80_20950	COG2723	6-phospho-beta-galactosidase activity
GII80_20955	COG1263	PTS System
GII80_20955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_20955	COG2190	(PTS) system
GII80_20970	COG5444	nuclease activity
GII80_20985	COG3507	Belongs to the glycosyl hydrolase 43 family
GII80_21000	COG2986	histidine ammonia-lyase
GII80_21005	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII80_21010	COG1228	amidohydrolase
GII80_21015	COG0010	Belongs to the arginase family
GII80_21020	COG0833	amino acid
GII80_21025	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII80_21030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII80_21035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII80_21040	COG2390	Transcriptional regulator
GII80_21050	COG3192	ethanolamine utilization protein
GII80_21055	COG2079	MmgE PrpD family protein
GII80_21065	COG1126	abc transporter atp-binding protein
GII80_21070	COG0765	amino acid transport
GII80_21075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII80_21095	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII80_21100	COG0561	phosphatase activity
GII80_21130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII80_21135	COG5294	Protein conserved in bacteria
GII80_21140	COG0577	efflux transmembrane transporter activity
GII80_21145	COG1136	(ABC) transporter
GII80_21150	COG2205	protein histidine kinase activity
GII80_21155	COG0745	RESPONSE REGULATOR receiver
GII80_21160	COG0191	fructose-bisphosphate aldolase activity
GII80_21165	COG1082	Xylose isomerase domain protein TIM barrel
GII80_21170	COG1082	Xylose isomerase domain protein TIM barrel
GII80_21175	COG0673	inositol 2-dehydrogenase activity
GII80_21180	COG2814	Major facilitator Superfamily
GII80_21185	COG1082	Xylose isomerase domain protein TIM barrel
GII80_21190	COG3962	Belongs to the TPP enzyme family
GII80_21195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII80_21200	COG3718	enzyme involved in inositol metabolism
GII80_21205	COG1012	belongs to the aldehyde dehydrogenase family
GII80_21210	COG1349	DNA-binding transcription factor activity
GII80_21215	COG0667	Aldo Keto reductase
GII80_21230	COG2814	Major facilitator Superfamily
GII80_21235	COG0326	Molecular chaperone. Has ATPase activity
GII80_21245	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_21250	COG1309	transcriptional regulator
GII80_21255	COG1012	belongs to the aldehyde dehydrogenase family
GII80_21260	COG0456	acetyltransferase
GII80_21265	COG2850	peptidyl-arginine hydroxylation
GII80_21270	COG2226	methyltransferase
GII80_21285	COG0367	asparagine synthase
GII80_21290	COG2814	Major facilitator Superfamily
GII80_21295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GII80_21305	COG1714	RDD family
GII80_21310	COG2311	Membrane
GII80_21315	COG1917	Cupin 2, conserved barrel domain protein
GII80_21320	COG1309	transcriptional regulator
GII80_21325	COG1028	Short-chain dehydrogenase reductase Sdr
GII80_21330	COG1846	Transcriptional regulator
GII80_21335	COG1380	Effector of murein hydrolase LrgA
GII80_21340	COG1346	cytolysis
GII80_21345	COG5039	Polysaccharide pyruvyl transferase
GII80_21350	COG1929	Belongs to the glycerate kinase type-1 family
GII80_21355	COG1802	Transcriptional regulator
GII80_21360	COG1070	Carbohydrate kinase
GII80_21365	COG2610	gluconate transmembrane transporter activity
GII80_21370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII80_21375	COG0450	alkyl hydroperoxide reductase
GII80_21380	COG3634	alkyl hydroperoxide reductase activity
GII80_21385	COG2723	6-phospho-beta-galactosidase activity
GII80_21390	COG2190	(PTS) system
GII80_21395	COG2190	(PTS) system
GII80_21395	COG1263	PTS System
GII80_21395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII80_21400	COG2188	Transcriptional regulator
GII80_21415	COG1131	(ABC) transporter
GII80_21420	COG1994	Peptidase M50
GII80_21425	COG0535	radical SAM domain protein
GII80_21435	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII80_21440	COG5293	efflux transmembrane transporter activity
GII80_21450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII80_21455	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII80_21470	COG1063	alcohol dehydrogenase
GII80_21490	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII80_21495	COG0456	acetyltransferase
GII80_21500	COG0457	Tetratricopeptide repeat
GII80_21510	COG0010	Belongs to the arginase family
GII80_21515	COG0833	amino acid
GII80_21520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII80_21525	COG3829	transcription factor binding
GII80_21540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII80_21545	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII80_21550	COG4853	Protein conserved in bacteria
GII80_21555	COG4863	YycH protein
GII80_21560	COG5002	protein histidine kinase activity
GII80_21565	COG0745	RESPONSE REGULATOR receiver
GII80_21595	COG0346	lactoylglutathione lyase activity
GII80_21600	COG0305	Participates in initiation and elongation during chromosome replication
GII80_21615	COG3093	addiction module antidote protein HigA
GII80_21620	COG2807	transmembrane transport
GII80_21625	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII80_21630	COG0359	binds to the 23S rRNA
GII80_21635	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII80_21640	COG4241	membrane
GII80_21650	COG5577	PFAM Coat F domain
GII80_21655	COG1733	regulation of RNA biosynthetic process
GII80_21660	COG1227	inorganic diphosphatase activity
GII80_21675	COG2271	Major facilitator Superfamily
GII80_21710	COG1131	(ABC) transporter
GII80_21725	COG4319	ketosteroid isomerase
GII80_21730	COG1357	PFAM Pentapeptide repeats (8 copies)
GII80_21735	COG2814	Major facilitator Superfamily
GII80_21740	COG0583	DNA-binding transcription factor activity
GII80_21745	COG2153	protein acetylation
GII80_21755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII80_21760	COG1846	Transcriptional regulator
GII80_21765	COG2153	protein acetylation
GII80_21770	COG2364	Membrane
GII80_21775	COG0456	acetyltransferase
GII80_21780	COG2315	Protein conserved in bacteria
GII80_21785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII80_21795	COG2814	Major facilitator Superfamily
GII80_21805	COG1331	Highly conserved protein containing a thioredoxin domain
GII80_21810	COG0789	Transcriptional regulator
GII80_21815	COG0697	spore germination
GII80_21820	COG1331	Highly conserved protein containing a thioredoxin domain
GII80_21825	COG1266	CAAX protease self-immunity
GII80_21830	COG0477	Major facilitator Superfamily
GII80_21830	COG2814	Major facilitator Superfamily
GII80_21835	COG0110	maltose O-acetyltransferase activity
GII80_21840	COG0346	lactoylglutathione lyase activity
GII80_21845	COG1609	Transcriptional regulator
GII80_21850	COG0708	Exodeoxyribonuclease III
GII80_21855	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII80_21860	COG0629	single-stranded DNA binding
GII80_21865	COG0360	Binds together with S18 to 16S ribosomal RNA
GII80_21870	COG0012	GTP binding
GII80_21875	COG0243	molybdopterin cofactor binding
GII80_21880	COG4481	Protein conserved in bacteria
GII80_21885	COG3949	Membrane
GII80_21895	COG1475	DNA binding
GII80_21900	COG1192	Involved in chromosome partitioning
GII80_21910	COG1475	DNA binding
GII80_21915	COG0357	Ribosomal RNA small subunit methyltransferase G
GII80_21920	COG0445	tRNA wobble uridine modification
GII80_21925	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII80_21930	COG1847	R3H domain protein
GII80_21935	COG0706	membrane insertase activity
GII80_21940	COG0594	ribonuclease P activity
GII80_21945	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GII80_21985	COG0187	DNA topoisomerase II activity
GII80_21990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII80_22055	COG5444	nuclease activity
GII80_22110	COG3953	SLT domain
GII80_22110	COG5280	Phage tail tape measure protein TP901
GII80_22215	COG3584	3D domain protein
GII80_22215	COG1388	LysM domain
GII80_22225	COG0582	viral genome integration into host DNA
GII80_22295	COG2887	Belongs to the helicase family. UvrD subfamily
GII80_22300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII80_22305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII80_22310	COG0716	FMN binding
GII80_22350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII80_22385	COG0328	RNA-DNA hybrid ribonuclease activity
GII80_22400	COG0587	DNA-directed DNA polymerase activity
GII80_22420	COG0194	GDP metabolic process