locus-tag	class	description
GII81_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII81_00010	COG0592	DNA-directed DNA polymerase activity
GII81_00015	COG2501	S4 domain
GII81_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII81_00030	COG0187	DNA topoisomerase II activity
GII81_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII81_00070	COG0516	GMP reductase activity
GII81_00070	COG0517	IMP dehydrogenase activity
GII81_00075	COG1686	Belongs to the peptidase S11 family
GII81_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII81_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII81_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII81_00100	COG1428	Deoxynucleoside kinase
GII81_00105	COG1428	Deoxynucleoside kinase
GII81_00110	COG3858	chitin binding
GII81_00110	COG1388	LysM domain
GII81_00115	COG1335	isochorismatase
GII81_00120	COG0590	tRNA wobble adenosine to inosine editing
GII81_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII81_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII81_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII81_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII81_00190	COG3853	Toxic anion resistance protein (TelA)
GII81_00195	COG1982	Orn Lys Arg decarboxylase major
GII81_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII81_00205	COG3870	Protein conserved in bacteria
GII81_00210	COG1728	Protein conserved in bacteria
GII81_00215	COG0470	DNA polymerase III
GII81_00220	COG1774	PSP1 C-terminal conserved region
GII81_00225	COG4467	Involved in initiation control of chromosome replication
GII81_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII81_00235	COG2827	Endonuclease containing a URI domain
GII81_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII81_00245	COG2002	toxin-antitoxin pair type II binding
GII81_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII81_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII81_00255	COG0084	hydrolase, TatD family'
GII81_00260	COG3584	3D domain protein
GII81_00260	COG3583	domain protein
GII81_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII81_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII81_00280	COG4466	Protein conserved in bacteria
GII81_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII81_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII81_00300	COG0251	oxidation-reduction process
GII81_00305	COG2088	sporulation resulting in formation of a cellular spore
GII81_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII81_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII81_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII81_00325	COG0193	aminoacyl-tRNA hydrolase activity
GII81_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII81_00340	COG2002	toxin-antitoxin pair type II binding
GII81_00345	COG2244	polysaccharide biosynthetic process
GII81_00350	COG3956	TIGRFAM MazG family protein
GII81_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII81_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII81_00375	COG1098	S1 RNA binding domain
GII81_00390	COG2208	phosphoserine phosphatase activity
GII81_00395	COG2304	oxidoreductase activity
GII81_00400	COG0515	serine threonine protein kinase
GII81_00405	COG0037	tRNA processing
GII81_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII81_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII81_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII81_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII81_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII81_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII81_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII81_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII81_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII81_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII81_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII81_00470	COG1396	sequence-specific DNA binding
GII81_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII81_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII81_00560	COG4463	regulation of RNA biosynthetic process
GII81_00565	COG3880	PFAM UvrB UvrC protein
GII81_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII81_00575	COG0542	response to heat
GII81_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII81_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII81_00590	COG4956	integral membrane protein (PIN domain superfamily)
GII81_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII81_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII81_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII81_00610	COG1045	serine acetyltransferase
GII81_00615	COG0215	cysteine-tRNA ligase activity
GII81_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII81_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII81_00630	COG3688	RNA-binding protein containing a PIN domain
GII81_00635	COG1595	DNA-templated transcription, initiation
GII81_00640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII81_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII81_00650	COG0250	Participates in transcription elongation, termination and antitermination
GII81_00655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GII81_00660	COG0081	regulation of translation
GII81_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII81_00670	COG0222	ribosome binding
GII81_00675	COG2813	Specifically methylates the guanine in position
GII81_00680	COG0085	RNA polymerase activity
GII81_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII81_00690	COG1358	cellular component organization or biogenesis
GII81_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII81_00700	COG0049	tRNA binding
GII81_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII81_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII81_00715	COG0596	Alpha beta hydrolase
GII81_00720	COG0051	transcription antitermination factor activity, RNA binding
GII81_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII81_00730	COG0088	Forms part of the polypeptide exit tunnel
GII81_00735	COG0089	rRNA binding
GII81_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII81_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GII81_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GII81_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GII81_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII81_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
GII81_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII81_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII81_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII81_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII81_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII81_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII81_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII81_00815	COG1841	ribosomal large subunit assembly
GII81_00820	COG0200	Binds to the 23S rRNA
GII81_00825	COG0201	protein transport
GII81_00830	COG0563	adenylate kinase activity
GII81_00835	COG0024	Methionine aminopeptidase
GII81_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII81_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GII81_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII81_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII81_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII81_00865	COG0202	RNA polymerase activity
GII81_00870	COG0203	ribosomal protein L17
GII81_00875	COG1122	ATPase activity
GII81_00880	COG1122	ATPase activity
GII81_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII81_00890	COG0101	tRNA pseudouridine synthase activity
GII81_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII81_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII81_00905	COG2226	methyltransferase
GII81_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_00920	COG0489	protein tyrosine kinase activity
GII81_00930	COG2194	sulfuric ester hydrolase activity
GII81_00935	COG0726	polysaccharide deacetylase
GII81_01015	COG0659	secondary active sulfate transmembrane transporter activity
GII81_01020	COG0385	Bile acid
GII81_01025	COG2819	hydrolase of the alpha beta superfamily
GII81_01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_01045	COG2207	Transcriptional regulator
GII81_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_01050	COG3876	Protein conserved in bacteria
GII81_01055	COG1472	Belongs to the glycosyl hydrolase 3 family
GII81_01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII81_01065	COG1263	PTS System
GII81_01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_01070	COG1737	Transcriptional regulator
GII81_01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII81_01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_01085	COG1683	Conserved Protein
GII81_01115	COG1595	DNA-templated transcription, initiation
GII81_01120	COG5662	AntiSigma factor
GII81_01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII81_01130	COG4856	YbbR-like protein
GII81_01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII81_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII81_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII81_01160	COG2169	Transcriptional regulator
GII81_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII81_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII81_01175	COG3002	Belongs to the UPF0753 family
GII81_01180	COG0288	reversible hydration of carbon dioxide
GII81_01190	COG5609	conserved protein (DUF2294)
GII81_01195	COG0640	Transcriptional regulator
GII81_01200	COG2814	Major facilitator Superfamily
GII81_01215	COG1404	Belongs to the peptidase S8 family
GII81_01235	COG1132	(ABC) transporter
GII81_01240	COG0596	Alpha beta hydrolase
GII81_01245	COG0745	RESPONSE REGULATOR receiver
GII81_01250	COG0642	Histidine kinase
GII81_01260	COG0515	serine threonine protein kinase
GII81_01275	COG1113	amino acid transport
GII81_01290	COG2602	Beta-lactamase
GII81_01295	COG2124	cytochrome p450
GII81_01305	COG0531	amino acid
GII81_01310	COG0584	glycerophosphoryl diester phosphodiesterase
GII81_01315	COG2271	Major facilitator Superfamily
GII81_01325	COG1846	Transcriptional regulator
GII81_01325	COG0456	acetyltransferase
GII81_01330	COG2271	Major facilitator Superfamily
GII81_01340	COG3409	Peptidoglycan-binding domain 1 protein
GII81_01345	COG0697	spore germination
GII81_01350	COG1917	Cupin 2, conserved barrel domain protein
GII81_01350	COG2207	Transcriptional regulator
GII81_01355	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII81_01360	COG3591	Belongs to the peptidase S1B family
GII81_01370	COG0596	Alpha beta hydrolase
GII81_01375	COG1183	phosphatidylcholine synthase activity
GII81_01380	COG0586	Pfam SNARE associated Golgi protein
GII81_01385	COG0688	phosphatidylethanolamine metabolic process
GII81_01395	COG2312	Erythromycin esterase
GII81_01405	COG1301	dicarboxylic acid transport
GII81_01410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_01410	COG2190	(PTS) system
GII81_01410	COG1263	PTS System
GII81_01415	COG0363	glucosamine-6-phosphate deaminase activity
GII81_01430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII81_01435	COG0833	amino acid
GII81_01440	COG2040	homocysteine
GII81_01450	COG1115	amino acid carrier protein
GII81_01455	COG2066	Belongs to the glutaminase family
GII81_01460	COG4191	Histidine kinase
GII81_01465	COG0784	Response regulator, receiver
GII81_01470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII81_01475	COG1012	belongs to the aldehyde dehydrogenase family
GII81_01480	COG2271	Major facilitator Superfamily
GII81_01485	COG4948	Mandelate Racemase Muconate Lactonizing
GII81_01490	COG2186	Transcriptional regulator
GII81_01495	COG2721	sulfolactate sulfo-lyase activity
GII81_01500	COG3173	Aminoglycoside phosphotransferase
GII81_01515	COG0745	RESPONSE REGULATOR receiver
GII81_01520	COG2205	protein histidine kinase activity
GII81_01525	COG1131	(ABC) transporter
GII81_01545	COG3773	Cell wall hydrolase
GII81_01550	COG2304	oxidoreductase activity
GII81_01560	COG3540	Alkaline phosphatase
GII81_01565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII81_01570	COG0805	protein transport
GII81_01575	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII81_01580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII81_01585	COG0477	Major facilitator Superfamily
GII81_01590	COG1309	transcriptional regulator
GII81_01595	COG0252	asparaginase activity
GII81_01600	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII81_01605	COG1714	RDD family
GII81_01610	COG3012	SEC-C Motif Domain Protein
GII81_01610	COG1405	negative regulation of cell septum assembly
GII81_01615	COG3290	protein histidine kinase activity
GII81_01620	COG3279	Response regulator of the LytR AlgR family
GII81_01625	COG4555	ABC transporter
GII81_01630	COG1668	transmembrane transport
GII81_01635	COG0667	Aldo Keto reductase
GII81_01650	COG1595	DNA-templated transcription, initiation
GII81_01655	COG1595	DNA-templated transcription, initiation
GII81_01660	COG1876	peptidase activity
GII81_01665	COG0457	Tetratricopeptide repeat
GII81_01670	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_01675	COG0366	Alpha amylase catalytic
GII81_01680	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII81_01685	COG1121	(ABC) transporter
GII81_01690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII81_01695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_01700	COG2310	stress, protein
GII81_01705	COG2310	stress, protein
GII81_01710	COG2310	stress, protein
GII81_01715	COG0861	Integral membrane protein TerC family
GII81_01725	COG3853	Toxic anion resistance protein (TelA)
GII81_01730	COG0477	Major facilitator Superfamily
GII81_01735	COG2814	Major facilitator Superfamily
GII81_01740	COG0640	Transcriptional regulator
GII81_01745	COG0517	IMP dehydrogenase activity
GII81_01745	COG4175	Glycine betaine
GII81_01750	COG4176	ABC-type proline glycine betaine transport system permease component
GII81_01755	COG2113	Glycine betaine
GII81_01760	COG1473	amidohydrolase
GII81_01765	COG1288	antiporter activity
GII81_01775	COG0366	Alpha amylase catalytic
GII81_01780	COG0039	L-malate dehydrogenase activity
GII81_01785	COG1620	l-lactate permease
GII81_01790	COG2814	Major facilitator Superfamily
GII81_01795	COG1846	Transcriptional regulator
GII81_01800	COG1280	lysine exporter protein (LysE YggA)
GII81_01805	COG3403	YqcI/YcgG family
GII81_01810	COG1113	amino acid transport
GII81_01815	COG3665	Urea carboxylase-associated protein
GII81_01820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII81_01825	COG1660	Displays ATPase and GTPase activities
GII81_01830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII81_01835	COG2226	methyltransferase
GII81_01840	COG0583	DNA-binding transcription factor activity
GII81_01845	COG3458	cephalosporin-C deacetylase activity
GII81_01850	COG3541	Predicted nucleotidyltransferase
GII81_01855	COG0506	proline dehydrogenase activity
GII81_01860	COG1012	belongs to the aldehyde dehydrogenase family
GII81_01865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII81_01870	COG2508	Transcriptional regulator
GII81_01875	COG3689	TIGRFAM TIGR03943 family protein
GII81_01880	COG0701	Predicted permease
GII81_01885	COG2267	carboxylic ester hydrolase activity
GII81_01890	COG0492	ferredoxin-NADP+ reductase activity
GII81_01895	COG1587	Uroporphyrinogen-III synthase
GII81_01895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII81_01900	COG2146	nitrite reductase [NAD(P)H] activity
GII81_01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII81_01910	COG0243	molybdopterin cofactor binding
GII81_01915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII81_01920	COG2223	nitrite transmembrane transporter activity
GII81_01925	COG1469	GTP cyclohydrolase I activity
GII81_01930	COG1376	ErfK ybiS ycfS ynhG family protein
GII81_01940	COG0523	cobalamin synthesis protein
GII81_01945	COG0765	amino acid transport
GII81_01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_01960	COG1714	RDD family
GII81_01970	COG2723	6-phospho-beta-galactosidase activity
GII81_01980	COG3209	COG3209 Rhs family protein
GII81_01985	COG0840	transmembrane signaling receptor activity
GII81_01985	COG3290	protein histidine kinase activity
GII81_01990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII81_01995	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII81_02000	COG1733	regulation of RNA biosynthetic process
GII81_02005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_02010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_02020	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII81_02025	COG2814	Major facilitator Superfamily
GII81_02035	COG0697	spore germination
GII81_02050	COG2364	Membrane
GII81_02055	COG1126	abc transporter atp-binding protein
GII81_02060	COG0765	amino acid transport
GII81_02065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_02070	COG0583	DNA-binding transcription factor activity
GII81_02075	COG0163	prenyltransferase activity
GII81_02080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII81_02095	COG0596	Alpha beta hydrolase
GII81_02100	COG3104	oligopeptide transport
GII81_02105	COG5434	Belongs to the glycosyl hydrolase 28 family
GII81_02115	COG0697	spore germination
GII81_02125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII81_02130	COG1136	(ABC) transporter
GII81_02135	COG0577	efflux transmembrane transporter activity
GII81_02140	COG0745	RESPONSE REGULATOR receiver
GII81_02145	COG5002	protein histidine kinase activity
GII81_02145	COG3850	Histidine kinase
GII81_02150	COG0457	Tetratricopeptide repeat
GII81_02170	COG0527	aspartate kinase activity
GII81_02175	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_02180	COG4605	iron ion homeostasis
GII81_02185	COG4604	ABC transporter, ATP-binding protein
GII81_02190	COG4607	ABC-type enterochelin transport system periplasmic component
GII81_02195	COG2814	Major facilitator Superfamily
GII81_02200	COG1309	transcriptional regulator
GII81_02205	COG0778	Nitroreductase
GII81_02210	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII81_02215	COG0640	Transcriptional regulator
GII81_02220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_02225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII81_02230	COG1012	belongs to the aldehyde dehydrogenase family
GII81_02235	COG4975	Glucose uptake
GII81_02240	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_02245	COG4549	nuclear export factor GLE1
GII81_02250	COG2372	response to copper ion
GII81_02250	COG1276	copper resistance
GII81_02255	COG1349	DNA-binding transcription factor activity
GII81_02265	COG2213	PTS system mannitol-specific
GII81_02270	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_02275	COG0246	Mannitol dehydrogenase
GII81_02280	COG0473	3-isopropylmalate dehydrogenase activity
GII81_02285	COG0681	Belongs to the peptidase S26 family
GII81_02290	COG0412	Dienelactone hydrolase
GII81_02295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII81_02305	COG0561	phosphatase activity
GII81_02310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII81_02315	COG1914	H( )-stimulated, divalent metal cation uptake system
GII81_02320	COG4336	lyase activity
GII81_02325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII81_02330	COG1984	allophanate hydrolase subunit 2
GII81_02335	COG1414	Transcriptional regulator
GII81_02340	COG2755	lipolytic protein G-D-S-L family
GII81_02350	COG2329	Antibiotic biosynthesis monooxygenase
GII81_02355	COG0768	penicillin binding
GII81_02360	COG4989	oxidoreductase activity
GII81_02365	COG3711	transcriptional antiterminator
GII81_02370	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_02375	COG2226	methyltransferase
GII81_02380	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_02385	COG1917	Cupin 2, conserved barrel domain protein
GII81_02390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_02395	COG3871	stress protein (general stress protein 26)
GII81_02405	COG2814	Major facilitator Superfamily
GII81_02410	COG1522	sequence-specific DNA binding
GII81_02415	COG0551	DNA topoisomerase type I activity
GII81_02415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII81_02420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII81_02425	COG3706	GGDEF domain
GII81_02430	COG5298	Protein conserved in bacteria
GII81_02435	COG1215	transferase activity, transferring glycosyl groups
GII81_02445	COG0531	amino acid
GII81_02450	COG0494	nUDIX hydrolase
GII81_02455	COG0028	Belongs to the TPP enzyme family
GII81_02470	COG1914	H( )-stimulated, divalent metal cation uptake system
GII81_02475	COG2261	transglycosylase associated protein
GII81_02480	COG4876	unkown
GII81_02485	COG2217	Heavy metal translocating P-type atpase
GII81_02490	COG3729	General stress protein
GII81_02495	COG0662	Cupin 2, conserved barrel domain protein
GII81_02500	COG2329	Antibiotic biosynthesis monooxygenase
GII81_02505	COG3546	catalase activity
GII81_02510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII81_02515	COG3290	protein histidine kinase activity
GII81_02520	COG4565	transcriptional regulatory protein
GII81_02525	COG1301	dicarboxylic acid transport
GII81_02530	COG0628	permease
GII81_02535	COG1131	(ABC) transporter
GII81_02540	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII81_02550	COG1960	acyl-CoA dehydrogenase activity
GII81_02565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII81_02570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_02575	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII81_02580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII81_02585	COG0513	Belongs to the DEAD box helicase family
GII81_02590	COG3402	PFAM membrane-flanked domain
GII81_02595	COG3428	Bacterial PH domain
GII81_02600	COG0705	Rhomboid family
GII81_02605	COG0736	holo-[acyl-carrier-protein] synthase activity
GII81_02610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII81_02615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII81_02620	COG0864	Transcriptional regulator
GII81_02625	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII81_02630	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_02635	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_02640	COG2172	sigma factor antagonist activity
GII81_02645	COG2208	phosphoserine phosphatase activity
GII81_02650	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_02655	COG2172	sigma factor antagonist activity
GII81_02660	COG1191	sigma factor activity
GII81_02665	COG2208	phosphoserine phosphatase activity
GII81_02670	COG2183	response to ionizing radiation
GII81_02680	COG3091	SprT-like family
GII81_02720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_02765	COG1476	TRANSCRIPTIONal
GII81_02785	COG0693	protein deglycase activity
GII81_02790	COG1278	Cold shock
GII81_02795	COG1329	Transcriptional regulator
GII81_02800	COG0697	spore germination
GII81_02805	COG1917	Cupin 2, conserved barrel domain protein
GII81_02805	COG2207	Transcriptional regulator
GII81_02810	COG0697	spore germination
GII81_02815	COG3708	Transcriptional regulator
GII81_02815	COG2207	Transcriptional regulator
GII81_02820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_02825	COG0477	Major facilitator Superfamily
GII81_02835	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII81_02870	COG1309	transcriptional regulator
GII81_02875	COG0697	spore germination
GII81_02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_02885	COG2030	dehydratase
GII81_02890	COG3545	Serine hydrolase
GII81_02895	COG1733	regulation of RNA biosynthetic process
GII81_02900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_02905	COG2814	Major facilitator Superfamily
GII81_02910	COG1309	transcriptional regulator
GII81_02920	COG0640	Transcriptional regulator
GII81_02925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII81_02935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_02940	COG0697	spore germination
GII81_02945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_02950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII81_02955	COG0640	Transcriptional regulator
GII81_02960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII81_02975	COG4585	Histidine kinase
GII81_02980	COG2197	response regulator
GII81_02985	COG2409	Drug exporters of the RND superfamily
GII81_02990	COG0596	Alpha beta hydrolase
GII81_02995	COG1811	Na channel or pump
GII81_03000	COG0789	Transcriptional regulator
GII81_03000	COG4978	Transcriptional regulator
GII81_03005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII81_03010	COG0778	Nitroreductase
GII81_03015	COG0346	lactoylglutathione lyase activity
GII81_03020	COG2259	Doxx family
GII81_03025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_03040	COG2323	membrane
GII81_03045	COG2323	membrane
GII81_03050	COG0071	Belongs to the small heat shock protein (HSP20) family
GII81_03065	COG1309	transcriptional regulator
GII81_03075	COG0456	acetyltransferase
GII81_03085	COG0673	inositol 2-dehydrogenase activity
GII81_03090	COG1609	Transcriptional regulator
GII81_03095	COG2814	Major facilitator Superfamily
GII81_03110	COG1113	amino acid transport
GII81_03115	COG2318	DinB family
GII81_03120	COG1846	Transcriptional regulator
GII81_03125	COG1033	growth of symbiont in host cell
GII81_03125	COG2409	Drug exporters of the RND superfamily
GII81_03130	COG0778	Nitroreductase
GII81_03135	COG1846	Transcriptional regulator
GII81_03140	COG2814	Major facilitator Superfamily
GII81_03145	COG0730	response to heat
GII81_03150	COG1802	Transcriptional regulator
GII81_03155	COG1388	LysM domain
GII81_03155	COG3858	chitin binding
GII81_03160	COG1819	glycosyl
GII81_03170	COG1785	Belongs to the alkaline phosphatase family
GII81_03175	COG5646	InterPro IPR014922
GII81_03185	COG0454	-acetyltransferase
GII81_03190	COG1078	dGTPase activity
GII81_03195	COG1388	LysM domain
GII81_03200	COG2814	Major facilitator Superfamily
GII81_03205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII81_03210	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII81_03215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII81_03220	COG2723	6-phospho-beta-galactosidase activity
GII81_03225	COG2188	Transcriptional regulator
GII81_03230	COG1940	carbohydrate kinase activity
GII81_03235	COG1482	cell wall glycoprotein biosynthetic process
GII81_03240	COG4124	Belongs to the glycosyl hydrolase 26 family
GII81_03285	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII81_03290	COG0802	atpase or kinase
GII81_03295	COG1214	PFAM Peptidase M22, glycoprotease
GII81_03300	COG0456	acetyltransferase
GII81_03305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII81_03310	COG0488	(ABC) transporter
GII81_03315	COG0315	cyclic pyranopterin monophosphate synthase activity
GII81_03320	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII81_03325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII81_03330	COG0805	protein transport
GII81_03340	COG1266	CAAX protease self-immunity
GII81_03345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GII81_03350	COG0459	protein refolding
GII81_03360	COG1073	alpha beta
GII81_03365	COG0457	Tetratricopeptide repeat
GII81_03370	COG1063	alcohol dehydrogenase
GII81_03375	COG2211	Major facilitator Superfamily
GII81_03380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII81_03385	COG1842	Phage shock protein A
GII81_03390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII81_03395	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII81_03400	COG4260	virion core protein, lumpy skin disease virus
GII81_03410	COG2814	Major facilitator Superfamily
GII81_03415	COG1063	alcohol dehydrogenase
GII81_03420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII81_03425	COG0823	Involved in the tonB-independent uptake of proteins
GII81_03440	COG2267	carboxylic ester hydrolase activity
GII81_03450	COG2132	Multicopper oxidase
GII81_03455	COG1113	amino acid transport
GII81_03465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII81_03470	COG0714	Associated with various cellular activities
GII81_03475	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII81_03480	COG1305	Transglutaminase-like
GII81_03485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII81_03485	COG0519	Catalyzes the synthesis of GMP from XMP
GII81_03490	COG2252	PERMEase
GII81_03495	COG3064	Membrane
GII81_03505	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII81_03515	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII81_03520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII81_03525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII81_03530	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII81_03535	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII81_03540	COG0047	phosphoribosylformylglycinamidine synthase activity
GII81_03545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII81_03550	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII81_03555	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII81_03560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII81_03565	COG0138	bifunctional purine biosynthesis protein purh
GII81_03570	COG0151	Belongs to the GarS family
GII81_03575	COG1522	sequence-specific DNA binding
GII81_03580	COG0531	amino acid
GII81_03590	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII81_03595	COG1470	cell adhesion involved in biofilm formation
GII81_03600	COG4496	protein, YerC YecD
GII81_03605	COG0069	glutamate synthase activity
GII81_03610	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII81_03615	COG0210	DNA helicase
GII81_03620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII81_03625	COG4851	CamS sex pheromone cAM373 precursor
GII81_03630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII81_03635	COG1285	pathogenesis
GII81_03640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII81_03645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII81_03650	COG0154	amidase activity
GII81_03655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII81_03660	COG1309	transcriptional regulator
GII81_03665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII81_03670	COG1597	lipid kinase activity
GII81_03675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII81_03705	COG5444	nuclease activity
GII81_03715	COG3586	endonuclease activity
GII81_03725	COG0457	Tetratricopeptide repeat
GII81_03735	COG0217	transcriptional regulatory protein
GII81_03745	COG1309	transcriptional regulator
GII81_03750	COG3631	Ketosteroid isomerase-related protein
GII81_03755	COG0702	epimerase
GII81_03770	COG3546	catalase activity
GII81_03775	COG0454	-acetyltransferase
GII81_03785	COG5578	integral membrane protein
GII81_03790	COG2972	Histidine kinase
GII81_03795	COG2207	Transcriptional regulator
GII81_03795	COG4753	response regulator
GII81_03800	COG1653	transport
GII81_03805	COG1175	transmembrane transport
GII81_03810	COG0395	ABC-type sugar transport system, permease component
GII81_03815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII81_03820	COG2207	Transcriptional regulator
GII81_03825	COG2755	lipolytic protein G-D-S-L family
GII81_03835	COG5578	integral membrane protein
GII81_03840	COG3401	FG-GAP repeat protein
GII81_03845	COG3401	FG-GAP repeat protein
GII81_03850	COG2755	lipolytic protein G-D-S-L family
GII81_03855	COG1874	Beta-galactosidase
GII81_03865	COG1653	transport
GII81_03870	COG4209	transmembrane transport
GII81_03875	COG0395	ABC-type sugar transport system, permease component
GII81_03880	COG1486	melibiose metabolic process
GII81_03885	COG2323	membrane
GII81_03890	COG2329	Antibiotic biosynthesis monooxygenase
GII81_03895	COG0346	lactoylglutathione lyase activity
GII81_03910	COG5583	Uncharacterized small protein (DUF2292)
GII81_03915	COG0670	Belongs to the BI1 family
GII81_03920	COG0697	spore germination
GII81_03925	COG1846	Transcriptional regulator
GII81_03930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII81_03945	COG2124	cytochrome p450
GII81_03945	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII81_03950	COG1368	sulfuric ester hydrolase activity
GII81_03955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII81_03960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII81_03965	COG1442	glycosyl transferase family 8
GII81_03970	COG1216	Glycosyl transferase, family 2
GII81_03975	COG1442	glycosyl transferase family 8
GII81_03980	COG2223	nitrite transmembrane transporter activity
GII81_03985	COG1011	Hydrolase
GII81_03990	COG0531	amino acid
GII81_03995	COG1012	belongs to the aldehyde dehydrogenase family
GII81_04000	COG0840	transmembrane signaling receptor activity
GII81_04005	COG0488	(ABC) transporter
GII81_04015	COG0789	Transcriptional regulator
GII81_04020	COG2814	Major facilitator Superfamily
GII81_04030	COG0488	(ABC) transporter
GII81_04035	COG0513	Belongs to the DEAD box helicase family
GII81_04040	COG0456	acetyltransferase
GII81_04045	COG2130	NADP-dependent
GII81_04050	COG2211	Major facilitator Superfamily
GII81_04055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GII81_04060	COG1120	ATPase activity
GII81_04065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_04070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_04075	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII81_04090	COG3866	Pectate lyase
GII81_04095	COG0471	metal ion transport
GII81_04100	COG3290	protein histidine kinase activity
GII81_04105	COG4565	transcriptional regulatory protein
GII81_04110	COG3181	Tripartite tricarboxylate transporter family receptor
GII81_04115	COG2851	Citrate transporter
GII81_04120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_04125	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII81_04130	COG1254	Belongs to the acylphosphatase family
GII81_04135	COG2258	MOSC domain
GII81_04155	COG0024	Methionine aminopeptidase
GII81_04160	COG1263	PTS System
GII81_04160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_04165	COG1368	sulfuric ester hydrolase activity
GII81_04180	COG1115	amino acid carrier protein
GII81_04185	COG0531	amino acid
GII81_04200	COG0697	spore germination
GII81_04205	COG1263	PTS System
GII81_04205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_04210	COG0366	Alpha amylase catalytic
GII81_04215	COG2188	Transcriptional regulator
GII81_04220	COG0778	Nitroreductase
GII81_04225	COG0737	Belongs to the 5'-nucleotidase family
GII81_04230	COG0693	protein deglycase activity
GII81_04235	COG2814	Major facilitator Superfamily
GII81_04240	COG4840	Belongs to the UPF0435 family
GII81_04245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII81_04250	COG4980	gas vesicle protein
GII81_04255	COG1295	ribonuclease BN
GII81_04260	COG0477	Major facilitator Superfamily
GII81_04265	COG0387	Pfam Sodium calcium exchanger
GII81_04275	COG0668	transmembrane transport
GII81_04280	COG0535	radical SAM domain protein
GII81_04290	COG0726	polysaccharide deacetylase
GII81_04295	COG2084	Dehydrogenase
GII81_04300	COG0598	Magnesium transport protein CorA
GII81_04305	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII81_04310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII81_04320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII81_04325	COG4637	Psort location Cytoplasmic, score
GII81_04330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII81_04335	COG0022	dehydrogenase e1 component
GII81_04340	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII81_04345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII81_04350	COG3284	Transcriptional regulator
GII81_04360	COG1742	UPF0060 membrane protein
GII81_04385	COG4842	Belongs to the WXG100 family
GII81_04390	COG1486	melibiose metabolic process
GII81_04395	COG1737	Transcriptional regulator
GII81_04400	COG1263	PTS System
GII81_04400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_04405	COG1132	(ABC) transporter
GII81_04410	COG1132	(ABC) transporter
GII81_04415	COG2259	Doxx family
GII81_04420	COG2514	catechol 2,3-dioxygenase activity
GII81_04425	COG4585	Histidine kinase
GII81_04430	COG2197	response regulator
GII81_04435	COG1131	(ABC) transporter
GII81_04440	COG1511	domain protein
GII81_04440	COG0842	Transport permease protein
GII81_04445	COG0842	Transport permease protein
GII81_04450	COG1695	Transcriptional regulator
GII81_04455	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII81_04460	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII81_04465	COG2318	DinB family
GII81_04470	COG2814	Major facilitator Superfamily
GII81_04475	COG1846	Transcriptional regulator
GII81_04480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII81_04480	COG0392	lysyltransferase activity
GII81_04485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_04490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_04495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_04500	COG0384	phenazine biosynthesis protein PhzF
GII81_04505	COG0778	Nitroreductase
GII81_04520	COG1090	epimerase
GII81_04525	COG2137	regulation of response to DNA damage stimulus
GII81_04535	COG2814	Major facilitator Superfamily
GII81_04550	COG3103	Sh3 type 3 domain protein
GII81_04555	COG5658	integral membrane protein
GII81_04560	COG0596	Alpha beta hydrolase
GII81_04565	COG0463	Glycosyl transferase, family 2
GII81_04570	COG4485	Bacterial membrane protein, YfhO
GII81_04575	COG1988	membrane-bound metal-dependent
GII81_04580	COG1194	a g-specific adenine glycosylase
GII81_04590	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_04605	COG3557	Belongs to the UPF0374 family
GII81_04610	COG1132	(ABC) transporter
GII81_04615	COG4129	membrane
GII81_04620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII81_04625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII81_04630	COG0735	belongs to the Fur family
GII81_04740	COG4326	sporulation control protein
GII81_04750	COG5577	PFAM Coat F domain
GII81_04755	COG3340	Belongs to the peptidase S51 family
GII81_04760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII81_04765	COG0277	FAD linked oxidase domain protein
GII81_04775	COG0753	catalase activity
GII81_04780	COG1116	anion transmembrane transporter activity
GII81_04785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII81_04790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII81_04795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_04805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII81_04815	COG1476	TRANSCRIPTIONal
GII81_04825	COG3382	B3 4 domain protein
GII81_04830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII81_04840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII81_04845	COG0789	Transcriptional regulator
GII81_04850	COG1664	Polymer-forming cytoskeletal
GII81_04855	COG1664	Polymer-forming cytoskeletal
GII81_04860	COG2766	serine protein kinase
GII81_04865	COG2718	Belongs to the UPF0229 family
GII81_04870	COG1846	Transcriptional regulator
GII81_04875	COG1566	PFAM secretion protein HlyD family protein
GII81_04880	COG2814	Major facilitator Superfamily
GII81_04885	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII81_04905	COG1725	Transcriptional regulator
GII81_04910	COG1131	(ABC) transporter
GII81_04915	COG1131	(ABC) transporter
GII81_04920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII81_04925	COG1278	Cold shock
GII81_04930	COG1464	Belongs to the NlpA lipoprotein family
GII81_04935	COG3706	GGDEF domain
GII81_04940	COG1823	symporter activity
GII81_04960	COG5577	PFAM Coat F domain
GII81_04965	COG0737	Belongs to the 5'-nucleotidase family
GII81_04965	COG1525	nuclease
GII81_04965	COG4085	toxin activity
GII81_04970	COG3764	Sortase (surface protein transpeptidase)
GII81_04975	COG0564	pseudouridine synthase activity
GII81_04985	COG0517	IMP dehydrogenase activity
GII81_04990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII81_04995	COG3153	acetyltransferase
GII81_04995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII81_05000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII81_05005	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII81_05010	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII81_05015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII81_05020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII81_05025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII81_05030	COG4585	Histidine kinase
GII81_05030	COG2203	Gaf domain
GII81_05035	COG2197	response regulator
GII81_05040	COG0431	NADPH-dependent FMN reductase
GII81_05055	COG0791	NLP P60 protein
GII81_05055	COG1388	LysM domain
GII81_05060	COG1959	2 iron, 2 sulfur cluster binding
GII81_05065	COG0668	transmembrane transport
GII81_05070	COG2719	SpoVR family
GII81_05075	COG1785	Belongs to the alkaline phosphatase family
GII81_05080	COG1388	LysM domain
GII81_05080	COG0791	NLP P60 protein
GII81_05085	COG0583	DNA-binding transcription factor activity
GII81_05090	COG0372	Belongs to the citrate synthase family
GII81_05095	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_05100	COG0531	amino acid
GII81_05105	COG0733	neurotransmitter:sodium symporter activity
GII81_05110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_05115	COG0456	acetyltransferase
GII81_05130	COG1595	DNA-templated transcription, initiation
GII81_05135	COG0667	Aldo Keto reductase
GII81_05140	COG0204	Acyl-transferase
GII81_05145	COG1253	flavin adenine dinucleotide binding
GII81_05150	COG0789	Transcriptional regulator
GII81_05155	COG0436	Aminotransferase
GII81_05160	COG1253	flavin adenine dinucleotide binding
GII81_05165	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII81_05170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII81_05175	COG0584	glycerophosphoryl diester phosphodiesterase
GII81_05185	COG0668	transmembrane transport
GII81_05190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII81_05195	COG0726	polysaccharide deacetylase
GII81_05200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII81_05205	COG1757	Na H antiporter
GII81_05210	COG0589	response to stress
GII81_05220	COG1132	(ABC) transporter
GII81_05225	COG1132	(ABC) transporter
GII81_05230	COG0702	epimerase
GII81_05250	COG0189	ligase activity
GII81_05255	COG0189	ligase activity
GII81_05260	COG4399	Belongs to the UPF0754 family
GII81_05265	COG3679	Belongs to the UPF0342 family
GII81_05270	COG4335	DNA alkylation repair
GII81_05275	COG0561	phosphatase activity
GII81_05280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII81_05285	COG0475	glutathione-regulated potassium exporter activity
GII81_05290	COG0490	domain, Protein
GII81_05300	COG1024	Enoyl-CoA hydratase
GII81_05310	COG4152	abc transporter atp-binding protein
GII81_05315	COG1668	transmembrane transport
GII81_05320	COG0420	3'-5' exonuclease activity
GII81_05325	COG4717	serine-type aminopeptidase activity
GII81_05330	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII81_05340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII81_05370	COG1846	Transcriptional regulator
GII81_05375	COG4980	gas vesicle protein
GII81_05390	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII81_05395	COG0537	adenosine 5'-monophosphoramidase activity
GII81_05400	COG1131	(ABC) transporter
GII81_05405	COG4473	ABC transporter
GII81_05415	COG1473	amidohydrolase
GII81_05420	COG3069	C4-dicarboxylate transmembrane transporter activity
GII81_05430	COG2329	Antibiotic biosynthesis monooxygenase
GII81_05435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII81_05440	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII81_05455	COG1309	transcriptional regulator
GII81_05460	COG1511	domain protein
GII81_05465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII81_05470	COG4377	Putative membrane peptidase family (DUF2324)
GII81_05480	COG1363	Peptidase, m42
GII81_05485	COG4405	Protein conserved in bacteria
GII81_05490	COG1301	dicarboxylic acid transport
GII81_05500	COG1234	tRNA 3'-trailer cleavage
GII81_05505	COG0095	Lipoate-protein ligase
GII81_05510	COG0702	epimerase
GII81_05515	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_05525	COG0501	Belongs to the peptidase M48B family
GII81_05530	COG1404	Belongs to the peptidase S8 family
GII81_05535	COG0456	acetyltransferase
GII81_05540	COG0604	alcohol dehydrogenase
GII81_05545	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII81_05550	COG0406	alpha-ribazole phosphatase activity
GII81_05555	COG0183	Belongs to the thiolase family
GII81_05560	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_05565	COG1268	BioY protein
GII81_05570	COG0840	transmembrane signaling receptor activity
GII81_05575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII81_05575	COG0723	plastoquinol--plastocyanin reductase activity
GII81_05580	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_05590	COG4903	ComK protein
GII81_05595	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_05605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII81_05620	COG0398	Pfam SNARE associated Golgi protein
GII81_05625	COG0681	Belongs to the peptidase S26 family
GII81_05630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII81_05635	COG1846	Transcriptional regulator
GII81_05640	COG0738	Major facilitator superfamily
GII81_05645	COG0673	inositol 2-dehydrogenase activity
GII81_05650	COG0561	phosphatase activity
GII81_05655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII81_05660	COG1609	Transcriptional regulator
GII81_05665	COG3180	Ammonia monooxygenase
GII81_05670	COG2814	Major facilitator Superfamily
GII81_05670	COG0477	Major facilitator Superfamily
GII81_05675	COG4533	DNA binding
GII81_05685	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII81_05690	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII81_05695	COG1074	ATP-dependent DNA helicase activity
GII81_05700	COG0420	3'-5' exonuclease activity
GII81_05705	COG0419	ATPase involved in DNA repair
GII81_05710	COG1403	HNH endonuclease
GII81_05750	COG5337	Spore coat protein CotH
GII81_05755	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII81_05765	COG1404	Belongs to the peptidase S8 family
GII81_05775	COG0367	asparagine synthase
GII81_05780	COG2318	DinB family
GII81_05785	COG1562	ergosterol biosynthetic process
GII81_05790	COG0534	Mate efflux family protein
GII81_05795	COG2207	Transcriptional regulator
GII81_05795	COG1917	Cupin 2, conserved barrel domain protein
GII81_05800	COG1609	Transcriptional regulator
GII81_05805	COG0673	inositol 2-dehydrogenase activity
GII81_05810	COG2318	DinB family
GII81_05815	COG1279	arginine transmembrane transporter activity
GII81_05820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_05825	COG1357	PFAM Pentapeptide repeats (8 copies)
GII81_05830	COG2267	carboxylic ester hydrolase activity
GII81_05835	COG0529	Catalyzes the synthesis of activated sulfate
GII81_05840	COG2046	Belongs to the sulfate adenylyltransferase family
GII81_05845	COG0175	sulfate reduction
GII81_05850	COG2045	Belongs to the ComB family
GII81_05855	COG1809	phosphosulfolactate synthase activity
GII81_05860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_05865	COG4948	Mandelate Racemase Muconate Lactonizing
GII81_05870	COG2814	Major facilitator Superfamily
GII81_05875	COG0454	-acetyltransferase
GII81_05880	COG2153	protein acetylation
GII81_05885	COG0646	methionine synthase
GII81_05885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII81_05890	COG1666	GTP binding
GII81_05895	COG2996	Protein conserved in bacteria
GII81_05915	COG1695	Transcriptional regulator
GII81_05930	COG3227	Zinc metalloprotease (Elastase)
GII81_05935	COG1307	EDD domain protein, DegV family
GII81_05940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_05955	COG0561	phosphatase activity
GII81_05960	COG1073	alpha beta
GII81_05965	COG2151	metal-sulfur cluster biosynthetic enzyme
GII81_05975	COG0277	FAD linked oxidase domain protein
GII81_05980	COG2271	Major facilitator Superfamily
GII81_05985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII81_06000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII81_06005	COG0505	Belongs to the CarA family
GII81_06010	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII81_06015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII81_06030	COG2267	carboxylic ester hydrolase activity
GII81_06040	COG1744	ABC transporter substrate-binding protein PnrA-like
GII81_06055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII81_06060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII81_06065	COG5504	Zn-dependent protease
GII81_06070	COG0444	Belongs to the ABC transporter superfamily
GII81_06075	COG4608	Belongs to the ABC transporter superfamily
GII81_06085	COG0601	transmembrane transport
GII81_06090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII81_06100	COG0180	Tryptophanyl-tRNA synthetase
GII81_06105	COG4166	transmembrane transport
GII81_06110	COG0601	transmembrane transport
GII81_06115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII81_06120	COG0444	Belongs to the ABC transporter superfamily
GII81_06125	COG4608	Belongs to the ABC transporter superfamily
GII81_06130	COG2814	Major facilitator Superfamily
GII81_06135	COG0456	acetyltransferase
GII81_06140	COG1393	Belongs to the ArsC family
GII81_06145	COG0861	Integral membrane protein TerC family
GII81_06155	COG4862	establishment of competence for transformation
GII81_06165	COG4469	Competence protein
GII81_06170	COG1164	Oligoendopeptidase f
GII81_06185	COG2346	COG2346, Truncated hemoglobins
GII81_06190	COG0741	lytic transglycosylase activity
GII81_06195	COG4116	CYTH
GII81_06205	COG2357	RelA SpoT domain protein
GII81_06210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII81_06215	COG0564	pseudouridine synthase activity
GII81_06220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII81_06225	COG0569	domain protein
GII81_06225	COG0475	glutathione-regulated potassium exporter activity
GII81_06230	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII81_06235	COG0352	thiamine-phosphate diphosphorylase activity
GII81_06240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII81_06245	COG2104	thiamine diphosphate biosynthetic process
GII81_06250	COG2022	thiamine diphosphate biosynthetic process
GII81_06255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII81_06260	COG0351	phosphomethylpyrimidine kinase
GII81_06265	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII81_06320	COG0210	DNA helicase
GII81_06330	COG2153	protein acetylation
GII81_06335	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII81_06340	COG2382	esterase
GII81_06345	COG0626	cystathionine gamma-synthase activity
GII81_06350	COG0626	cystathionine gamma-synthase activity
GII81_06355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_06360	COG5505	Protein of unknown function (DUF819)
GII81_06385	COG5444	nuclease activity
GII81_06430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII81_06435	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_06445	COG3711	transcriptional antiterminator
GII81_06445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_06450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII81_06450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_06450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII81_06455	COG1482	cell wall glycoprotein biosynthetic process
GII81_06465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_06475	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII81_06490	COG0109	protoheme IX farnesyltransferase activity
GII81_06500	COG0726	polysaccharide deacetylase
GII81_06515	COG5504	Zn-dependent protease
GII81_06520	COG2205	protein histidine kinase activity
GII81_06530	COG3383	formate dehydrogenase (NAD+) activity
GII81_06535	COG2427	Protein of unknown function (DUF1641)
GII81_06545	COG1051	belongs to the nudix hydrolase family
GII81_06555	COG2124	cytochrome p450
GII81_06560	COG1819	glycosyl
GII81_06570	COG1587	Uroporphyrinogen-III synthase
GII81_06575	COG0390	transport system, permease component
GII81_06580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII81_06585	COG0697	spore germination
GII81_06590	COG4297	protein containing double-stranded beta helix domain
GII81_06600	COG1252	NADH dehydrogenase
GII81_06605	COG1904	glucuronate isomerase
GII81_06610	COG2211	Major facilitator Superfamily
GII81_06615	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII81_06620	COG1063	alcohol dehydrogenase
GII81_06625	COG1312	Catalyzes the dehydration of D-mannonate
GII81_06630	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_06635	COG2271	Major facilitator Superfamily
GII81_06640	COG1609	Transcriptional regulator
GII81_06645	COG0246	Mannitol dehydrogenase
GII81_06650	COG2721	sulfolactate sulfo-lyase activity
GII81_06655	COG0730	response to heat
GII81_06660	COG2318	DinB family
GII81_06665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII81_06670	COG0457	Tetratricopeptide repeat
GII81_06680	COG2350	Protein conserved in bacteria
GII81_06685	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_06685	COG3409	Peptidoglycan-binding domain 1 protein
GII81_06685	COG1388	LysM domain
GII81_06695	COG4195	phage-related replication protein
GII81_06700	COG3546	catalase activity
GII81_06705	COG2856	Zn peptidase
GII81_06710	COG1396	sequence-specific DNA binding
GII81_06720	COG1522	sequence-specific DNA binding
GII81_06725	COG1484	DNA-dependent DNA replication
GII81_06745	COG1595	DNA-templated transcription, initiation
GII81_06750	COG5484	DNA packaging
GII81_06750	COG3728	DNA packaging
GII81_06755	COG1783	phage Terminase large subunit
GII81_06760	COG5518	Phage portal protein
GII81_06765	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII81_06770	COG4653	Phage capsid family
GII81_06820	COG3953	SLT domain
GII81_06820	COG5412	phage tail tape measure protein
GII81_06820	COG3953	SLT domain
GII81_06820	COG5412	phage tail tape measure protein
GII81_06825	COG1652	LysM domain
GII81_06830	COG4193	domain, Protein
GII81_06840	COG3628	GPW Gp25 family protein
GII81_06845	COG3299	homolog of phage Mu protein gp47
GII81_06850	COG3778	Protein conserved in bacteria
GII81_06890	COG3409	Peptidoglycan-binding domain 1 protein
GII81_06890	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_06910	COG0306	phosphate transporter
GII81_06915	COG1392	Phosphate transport regulator
GII81_06920	COG0531	amino acid
GII81_06925	COG0346	lactoylglutathione lyase activity
GII81_06930	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII81_06935	COG0463	Glycosyl transferase, family 2
GII81_06940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII81_06945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII81_06950	COG2362	D-Aminopeptidase
GII81_06955	COG0601	transmembrane transport
GII81_06960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII81_06965	COG0444	Belongs to the ABC transporter superfamily
GII81_06970	COG4166	transmembrane transport
GII81_06975	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII81_06980	COG4948	Mandelate Racemase Muconate Lactonizing
GII81_06985	COG0791	NLP P60 protein
GII81_06990	COG4608	Belongs to the ABC transporter superfamily
GII81_06995	COG2706	6-phosphogluconolactonase activity
GII81_07000	COG1834	amidinotransferase
GII81_07005	COG1607	acyl-coa hydrolase
GII81_07010	COG1017	nitric oxide dioxygenase activity
GII81_07010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII81_07020	COG2323	membrane
GII81_07025	COG2318	DinB family
GII81_07030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_07035	COG2076	Multidrug Resistance protein
GII81_07040	COG2076	Multidrug Resistance protein
GII81_07045	COG0788	formyltetrahydrofolate deformylase activity
GII81_07050	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII81_07055	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII81_07060	COG1764	response to oxidative stress
GII81_07065	COG1846	Transcriptional regulator
GII81_07070	COG1764	response to oxidative stress
GII81_07075	COG0590	tRNA wobble adenosine to inosine editing
GII81_07080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII81_07085	COG1404	Belongs to the peptidase S8 family
GII81_07090	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_07095	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII81_07100	COG1122	ATPase activity
GII81_07105	COG4721	ABC-type cobalt transport system, permease component
GII81_07115	COG0745	RESPONSE REGULATOR receiver
GII81_07120	COG3850	Histidine kinase
GII81_07120	COG5002	protein histidine kinase activity
GII81_07125	COG3212	peptidase
GII81_07130	COG3212	peptidase
GII81_07140	COG2239	Acts as a magnesium transporter
GII81_07145	COG0789	Transcriptional regulator
GII81_07160	COG1846	Transcriptional regulator
GII81_07165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII81_07170	COG0726	polysaccharide deacetylase
GII81_07175	COG1408	metallophosphoesterase
GII81_07185	COG0463	Glycosyl transferase, family 2
GII81_07190	COG3285	dna ligase
GII81_07190	COG1793	dna ligase
GII81_07195	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII81_07200	COG5001	Diguanylate cyclase
GII81_07200	COG3300	MHYT domain
GII81_07205	COG0586	Pfam SNARE associated Golgi protein
GII81_07210	COG0861	Integral membrane protein TerC family
GII81_07215	COG1191	sigma factor activity
GII81_07235	COG0501	Belongs to the peptidase M48B family
GII81_07240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII81_07255	COG3594	Acyltransferase
GII81_07260	COG5002	protein histidine kinase activity
GII81_07265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII81_07275	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII81_07280	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII81_07285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII81_07290	COG0436	Aminotransferase
GII81_07295	COG1850	ribulose-bisphosphate carboxylase activity
GII81_07300	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII81_07305	COG0235	Class ii aldolase
GII81_07310	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII81_07315	COG3339	Conserved Protein
GII81_07330	COG3852	Histidine kinase
GII81_07335	COG1846	Transcriptional regulator
GII81_07340	COG1360	Flagellar Motor Protein
GII81_07345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII81_07350	COG0542	response to heat
GII81_07355	COG3949	Membrane
GII81_07360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII81_07365	COG0720	synthase
GII81_07370	COG0602	queuosine metabolic process
GII81_07375	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII81_07380	COG1733	regulation of RNA biosynthetic process
GII81_07385	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_07390	COG4641	Protein conserved in bacteria
GII81_07390	COG1388	LysM domain
GII81_07395	COG1388	LysM domain
GII81_07400	COG3858	chitin binding
GII81_07410	COG4873	Protein conserved in bacteria
GII81_07420	COG3773	Cell wall hydrolase
GII81_07425	COG2244	polysaccharide biosynthetic process
GII81_07430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_07435	COG2217	Heavy metal translocating P-type atpase
GII81_07445	COG0006	proline dipeptidase activity
GII81_07450	COG1609	Transcriptional regulator
GII81_07455	COG3711	transcriptional antiterminator
GII81_07460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_07460	COG1263	PTS System
GII81_07460	COG2190	(PTS) system
GII81_07465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_07470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII81_07480	COG1533	DNA photolyase activity
GII81_07485	COG0456	acetyltransferase
GII81_07490	COG0840	transmembrane signaling receptor activity
GII81_07495	COG2084	Dehydrogenase
GII81_07500	COG2340	Cysteine-rich secretory protein family
GII81_07505	COG0768	penicillin binding
GII81_07510	COG4191	Histidine kinase
GII81_07515	COG0436	Aminotransferase
GII81_07525	COG0835	chemotaxis
GII81_07525	COG0784	Response regulator, receiver
GII81_07535	COG2814	Major facilitator Superfamily
GII81_07540	COG1376	ErfK ybiS ycfS ynhG family protein
GII81_07545	COG1408	metallophosphoesterase
GII81_07550	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_07555	COG2200	EAL domain
GII81_07560	COG4703	Protein of unknown function (DUF1797)
GII81_07565	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII81_07575	COG0517	IMP dehydrogenase activity
GII81_07580	COG0583	DNA-binding transcription factor activity
GII81_07585	COG0716	FMN binding
GII81_07595	COG0716	FMN binding
GII81_07600	COG2171	N-acyltransferase activity
GII81_07605	COG1473	amidohydrolase
GII81_07615	COG0668	transmembrane transport
GII81_07620	COG0450	alkyl hydroperoxide reductase
GII81_07625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_07640	COG0746	molybdenum cofactor guanylyltransferase activity
GII81_07645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII81_07650	COG0303	'Molybdopterin
GII81_07655	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII81_07660	COG0314	molybdopterin synthase activity
GII81_07665	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII81_07670	COG1132	(ABC) transporter
GII81_07675	COG1132	(ABC) transporter
GII81_07685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII81_07690	COG1136	(ABC) transporter
GII81_07695	COG0577	efflux transmembrane transporter activity
GII81_07700	COG1349	DNA-binding transcription factor activity
GII81_07705	COG1105	Belongs to the carbohydrate kinase PfkB family
GII81_07710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII81_07710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII81_07710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_07715	COG0681	Belongs to the peptidase S26 family
GII81_07725	COG0488	(ABC) transporter
GII81_07730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII81_07735	COG2309	aminopeptidase activity
GII81_07745	COG1077	Cell shape determining protein MreB Mrl
GII81_07750	COG2002	toxin-antitoxin pair type II binding
GII81_07755	COG3852	Histidine kinase
GII81_07760	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII81_07760	COG2105	PFAM AIG2 family protein
GII81_07765	COG0569	domain protein
GII81_07770	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII81_07775	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII81_07785	COG0561	phosphatase activity
GII81_07790	COG0242	peptide deformylase activity
GII81_07800	COG0497	DNA recombination
GII81_07805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII81_07810	COG0022	dehydrogenase e1 component
GII81_07815	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII81_07820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII81_07825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_07835	COG1982	Orn Lys Arg decarboxylase major
GII81_07840	COG4476	Belongs to the UPF0223 family
GII81_07845	COG4493	Belongs to the UPF0637 family
GII81_07855	COG0483	inositol monophosphate 1-phosphatase activity
GII81_07865	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII81_07885	COG1595	DNA-templated transcription, initiation
GII81_07915	COG4896	Protein conserved in bacteria
GII81_07925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII81_07930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII81_07935	COG2066	Belongs to the glutaminase family
GII81_07940	COG4838	Belongs to the UPF0358 family
GII81_07945	COG0772	Belongs to the SEDS family
GII81_07950	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII81_07955	COG1612	heme a metabolic process
GII81_07960	COG0109	protoheme IX farnesyltransferase activity
GII81_07965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII81_07965	COG2010	Cytochrome c
GII81_07970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII81_07975	COG1845	cytochrome c oxidase, subunit III
GII81_07980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII81_07985	COG3336	cytochrome c oxidase
GII81_07995	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII81_08000	COG2340	Cysteine-rich secretory protein family
GII81_08015	COG3679	Belongs to the UPF0342 family
GII81_08020	COG4471	UPF0298 protein
GII81_08025	COG0742	ribosomal rna small subunit methyltransferase
GII81_08030	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII81_08035	COG3314	Sporulation integral membrane protein YlbJ
GII81_08040	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII81_08045	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII81_08050	COG1323	Belongs to the UPF0348 family
GII81_08060	COG1399	metal-binding, possibly nucleic acid-binding protein
GII81_08065	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GII81_08075	COG0454	-acetyltransferase
GII81_08080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII81_08085	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII81_08090	COG2001	Belongs to the MraZ family
GII81_08095	COG0275	rRNA processing
GII81_08100	COG4839	cell division protein FtsL
GII81_08110	COG0768	penicillin binding
GII81_08115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII81_08120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII81_08125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII81_08130	COG0772	Belongs to the SEDS family
GII81_08135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII81_08140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII81_08145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII81_08150	COG3879	Bacterial protein of unknown function (DUF881)
GII81_08155	COG3879	Bacterial protein of unknown function (DUF881)
GII81_08160	COG3856	small basic protein
GII81_08165	COG0849	cell division
GII81_08170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII81_08175	COG1404	Belongs to the peptidase S8 family
GII81_08175	COG4412	M6 family metalloprotease domain protein
GII81_08185	COG1191	sigma factor activity
GII81_08190	COG1191	sigma factor activity
GII81_08195	COG1119	ATPase activity
GII81_08200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII81_08205	COG1873	PFAM PRC-barrel domain
GII81_08215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII81_08220	COG1799	cell septum assembly
GII81_08225	COG0762	integral membrane protein
GII81_08230	COG2302	S4 RNA-binding domain
GII81_08235	COG3599	regulation of cell shape
GII81_08240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII81_08245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII81_08250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII81_08255	COG0564	pseudouridine synthase activity
GII81_08260	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII81_08265	COG2233	PERMEase
GII81_08270	COG0540	Belongs to the ATCase OTCase family
GII81_08275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII81_08280	COG0505	Belongs to the CarA family
GII81_08285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII81_08290	COG0543	2 iron, 2 sulfur cluster binding
GII81_08295	COG0167	dihydroorotate dehydrogenase activity
GII81_08300	COG0284	orotidine-5'-phosphate decarboxylase activity
GII81_08305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII81_08310	COG0175	sulfate reduction
GII81_08315	COG0306	phosphate transporter
GII81_08320	COG2046	Belongs to the sulfate adenylyltransferase family
GII81_08325	COG0529	Catalyzes the synthesis of activated sulfate
GII81_08330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII81_08335	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII81_08340	COG1648	precorrin-2 dehydrogenase activity
GII81_08350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII81_08355	COG1561	YicC-like family, N-terminal region
GII81_08360	COG2052	Domain of unknown function (DUF370)
GII81_08365	COG0194	GDP metabolic process
GII81_08370	COG1758	RNA polymerase activity
GII81_08375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII81_08380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII81_08385	COG0242	peptide deformylase activity
GII81_08390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII81_08395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII81_08395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII81_08400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII81_08405	COG0631	protein serine/threonine phosphatase activity
GII81_08410	COG0515	serine threonine protein kinase
GII81_08410	COG2815	serine threonine protein kinase
GII81_08415	COG1162	GTPase activity
GII81_08420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII81_08425	COG1564	THIamine pyrophosphokinase
GII81_08435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII81_08440	COG1302	Protein conserved in bacteria
GII81_08445	COG1461	Dihydroxyacetone kinase
GII81_08450	COG1760	l-serine dehydratase
GII81_08455	COG1760	l-serine dehydratase
GII81_08460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII81_08465	COG1349	DNA-binding transcription factor activity
GII81_08465	COG2050	protein possibly involved in aromatic compounds catabolism
GII81_08470	COG0416	fatty acid biosynthetic process
GII81_08475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII81_08480	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_08485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_08490	COG0571	ribonuclease III activity
GII81_08495	COG1196	nuclear chromosome segregation
GII81_08500	COG0552	protein localization to endoplasmic reticulum
GII81_08510	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII81_08515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII81_08520	COG0228	four-way junction DNA binding
GII81_08525	COG1837	Belongs to the UPF0109 family
GII81_08535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII81_08540	COG0336	Belongs to the RNA methyltransferase TrmD family
GII81_08545	COG0335	large ribosomal subunit rRNA binding
GII81_08550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII81_08555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII81_08565	COG2257	FlhB HrpN YscU SpaS Family
GII81_08570	COG0045	succinate-CoA ligase (ADP-forming) activity
GII81_08575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII81_08580	COG0758	DNA mediated transformation
GII81_08585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII81_08590	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII81_08595	COG4974	Belongs to the 'phage' integrase family
GII81_08600	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII81_08605	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII81_08610	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII81_08615	COG1815	bacterial-type flagellum-dependent cell motility
GII81_08620	COG1558	bacterial-type flagellum-dependent cell motility
GII81_08625	COG1677	Flagellar hook-basal body complex protein FliE
GII81_08630	COG1766	The M ring may be actively involved in energy transduction
GII81_08635	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII81_08640	COG1317	bacterial-type flagellum organization
GII81_08645	COG1157	protein secretion by the type III secretion system
GII81_08650	COG2882	bacterial-type flagellum organization
GII81_08655	COG3334	PFAM MgtE intracellular
GII81_08660	COG3144	bacterial-type flagellum assembly
GII81_08665	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII81_08670	COG4786	Flagellar basal body rod
GII81_08675	COG1582	Flagellar protein (FlbD)
GII81_08680	COG1580	Controls the rotational direction of flagella during chemotaxis
GII81_08685	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII81_08690	COG1776	CheC inhibitor of MCP methylation
GII81_08690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII81_08695	COG2201	protein-glutamate methylesterase activity
GII81_08700	COG3190	flagellar
GII81_08705	COG1338	Plays a role in the flagellum-specific transport system
GII81_08710	COG1987	bacterial-type flagellum assembly
GII81_08715	COG1684	flagellar biosynthetic protein fliR
GII81_08720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII81_08725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII81_08730	COG1419	protein localization to endoplasmic reticulum
GII81_08735	COG0455	bacterial-type flagellum organization
GII81_08740	COG2201	protein-glutamate methylesterase activity
GII81_08745	COG0643	Histidine kinase
GII81_08745	COG2198	Histidine kinase
GII81_08750	COG0835	chemotaxis
GII81_08755	COG1776	CheC inhibitor of MCP methylation
GII81_08760	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII81_08765	COG1191	sigma factor activity
GII81_08775	COG0052	Belongs to the universal ribosomal protein uS2 family
GII81_08780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII81_08785	COG0528	UMP kinase activity
GII81_08790	COG0233	cytoplasmic translational termination
GII81_08795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII81_08800	COG4589	Belongs to the CDS family
GII81_08805	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII81_08810	COG0750	zinc metalloprotease
GII81_08815	COG0442	prolyl-tRNA aminoacylation
GII81_08820	COG2176	DNA-directed DNA polymerase activity
GII81_08825	COG0779	Required for maturation of 30S ribosomal subunits
GII81_08830	COG0195	Participates in both transcription termination and antitermination
GII81_08835	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII81_08840	COG1358	cellular component organization or biogenesis
GII81_08845	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII81_08850	COG1550	Protein conserved in bacteria
GII81_08855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII81_08860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII81_08865	COG0196	riboflavin kinase activity
GII81_08870	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII81_08875	COG1185	polyribonucleotide nucleotidyltransferase activity
GII81_08880	COG0726	polysaccharide deacetylase
GII81_08885	COG0612	Peptidase, M16
GII81_08890	COG1873	PFAM PRC-barrel domain
GII81_08895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII81_08900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII81_08905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII81_08910	COG0527	aspartate kinase activity
GII81_08915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII81_08920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII81_08925	COG0740	serine-type endopeptidase activity
GII81_08935	COG1674	ftsk spoiiie
GII81_08935	COG4980	gas vesicle protein
GII81_08940	COG2188	Transcriptional regulator
GII81_08945	COG2814	Major facilitator Superfamily
GII81_08950	COG0612	Peptidase, M16
GII81_08955	COG0612	Peptidase, M16
GII81_08960	COG0300	oxidoreductase activity
GII81_08975	COG1426	Protein conserved in bacteria
GII81_08980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII81_08985	COG1546	Belongs to the CinA family
GII81_08985	COG1058	Belongs to the CinA family
GII81_08990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII81_08995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII81_09000	COG1418	mRNA catabolic process
GII81_09005	COG1692	metallophosphoesterase
GII81_09010	COG2359	stage V sporulation protein S
GII81_09015	COG1063	alcohol dehydrogenase
GII81_09020	COG0156	8-amino-7-oxononanoate synthase activity
GII81_09025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII81_09030	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII81_09040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII81_09045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII81_09060	COG3226	Transcriptional regulator
GII81_09065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_09075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII81_09080	COG3321	synthase
GII81_09085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII81_09085	COG2070	2-Nitropropane dioxygenase
GII81_09090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_09095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII81_09100	COG3425	synthase
GII81_09105	COG1024	Enoyl-CoA hydratase
GII81_09110	COG1024	Enoyl-CoA hydratase
GII81_09115	COG3321	synthase
GII81_09115	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_09115	COG0300	oxidoreductase activity
GII81_09115	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_09115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_09120	COG3321	synthase
GII81_09120	COG4221	oxidoreductase activity
GII81_09120	COG0300	oxidoreductase activity
GII81_09120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_09125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_09125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_09125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII81_09125	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_09125	COG3321	synthase
GII81_09130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_09130	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_09130	COG3321	synthase
GII81_09130	COG4221	oxidoreductase activity
GII81_09135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_09135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GII81_09135	COG3321	synthase
GII81_09135	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII81_09140	COG2124	cytochrome p450
GII81_09150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_09155	COG1404	Belongs to the peptidase S8 family
GII81_09165	COG4195	phage-related replication protein
GII81_09170	COG1764	response to oxidative stress
GII81_09175	COG2076	Multidrug Resistance protein
GII81_09180	COG2076	Multidrug Resistance protein
GII81_09195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII81_09200	COG1923	regulation of RNA biosynthetic process
GII81_09215	COG1780	Probably involved in ribonucleotide reductase function
GII81_09220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII81_09225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII81_09230	COG4112	unkown
GII81_09235	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_09240	COG0464	growth
GII81_09245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII81_09250	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII81_09255	COG0789	Transcriptional regulator
GII81_09260	COG0174	glutamine synthetase
GII81_09300	COG1598	PFAM Uncharacterised protein family UPF0150
GII81_09380	COG0463	Glycosyl transferase, family 2
GII81_09395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_09410	COG3655	Transcriptional regulator
GII81_09425	COG0135	phosphoribosylanthranilate isomerase activity
GII81_09435	COG2211	Major facilitator Superfamily
GII81_09440	COG3507	Belongs to the glycosyl hydrolase 43 family
GII81_09445	COG1940	carbohydrate kinase activity
GII81_09450	COG2115	Belongs to the xylose isomerase family
GII81_09455	COG1070	Carbohydrate kinase
GII81_09465	COG1525	nuclease
GII81_09470	COG2814	Major facilitator Superfamily
GII81_09475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII81_09485	COG0756	dUTP diphosphatase activity
GII81_09520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII81_09530	COG3832	glyoxalase III activity
GII81_09575	COG4195	phage-related replication protein
GII81_09585	COG0346	lactoylglutathione lyase activity
GII81_09590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII81_09595	COG1388	LysM domain
GII81_09600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII81_09605	COG4224	UPF0291 protein
GII81_09610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII81_09620	COG3763	UPF0154 protein
GII81_09630	COG0785	Cytochrome C biogenesis protein
GII81_09635	COG2201	protein-glutamate methylesterase activity
GII81_09640	COG4846	Membrane protein involved in cytochrome C biogenesis
GII81_09650	COG0071	Belongs to the small heat shock protein (HSP20) family
GII81_09665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII81_09670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_09690	COG0824	Thioesterase
GII81_09700	COG4841	protein insertion into membrane
GII81_09705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII81_09710	COG1832	CoA-binding protein
GII81_09715	COG0187	DNA topoisomerase II activity
GII81_09720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII81_09730	COG1115	amino acid carrier protein
GII81_09745	COG5520	Belongs to the glycosyl hydrolase 30 family
GII81_09750	COG3507	Belongs to the glycosyl hydrolase 43 family
GII81_09755	COG2246	polysaccharide biosynthetic process
GII81_09760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII81_09765	COG0586	Pfam SNARE associated Golgi protein
GII81_09770	COG2404	hydrolase activity, acting on ester bonds
GII81_09775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII81_09780	COG1024	Enoyl-CoA hydratase
GII81_09785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII81_09790	COG0511	ligase activity, forming carbon-carbon bonds
GII81_09795	COG0439	Biotin carboxylase
GII81_09800	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_09805	COG1960	acyl-CoA dehydrogenase activity
GII81_09820	COG1649	PFAM Uncharacterised BCR, COG1649
GII81_09830	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII81_09830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_09835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_09840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_09845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_09850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_09855	COG2027	D-alanyl-D-alanine carboxypeptidase
GII81_09860	COG2017	converts alpha-aldose to the beta-anomer
GII81_09865	COG0534	Mate efflux family protein
GII81_09880	COG0582	viral genome integration into host DNA
GII81_09885	COG0166	Belongs to the GPI family
GII81_09890	COG0405	Gamma-glutamyltransferase
GII81_09895	COG0583	DNA-binding transcription factor activity
GII81_09900	COG0604	alcohol dehydrogenase
GII81_09905	COG0493	'glutamate synthase
GII81_09910	COG0070	glutamate synthase
GII81_09910	COG0067	glutamate synthase
GII81_09910	COG0069	glutamate synthase activity
GII81_09915	COG0583	DNA-binding transcription factor activity
GII81_09920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII81_09925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII81_09935	COG0300	oxidoreductase activity
GII81_09940	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII81_09950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_09965	COG2814	Major facilitator Superfamily
GII81_09970	COG1070	Carbohydrate kinase
GII81_09975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII81_09980	COG0243	molybdopterin cofactor binding
GII81_10010	COG5278	phosphoserine phosphatase activity
GII81_10010	COG0840	transmembrane signaling receptor activity
GII81_10015	COG2368	4-hydroxyphenylacetate
GII81_10020	COG4305	rare lipoprotein A
GII81_10025	COG3619	membrane
GII81_10030	COG3866	Pectate lyase
GII81_10035	COG2135	peptidase activity
GII81_10045	COG2140	Oxalate decarboxylase
GII81_10055	COG0456	acetyltransferase
GII81_10075	COG2720	vancomycin resistance protein
GII81_10085	COG3655	Transcriptional regulator
GII81_10090	COG3739	integral membrane protein
GII81_10095	COG0583	DNA-binding transcription factor activity
GII81_10100	COG0697	spore germination
GII81_10110	COG0693	protein deglycase activity
GII81_10115	COG2367	Beta-lactamase
GII81_10140	COG0574	Belongs to the PEP-utilizing enzyme family
GII81_10140	COG3848	Pyruvate phosphate dikinase
GII81_10145	COG0726	polysaccharide deacetylase
GII81_10150	COG2314	TM2 domain
GII81_10155	COG1396	sequence-specific DNA binding
GII81_10275	COG0457	Tetratricopeptide repeat
GII81_10310	COG4282	regulation of fungal-type cell wall biogenesis
GII81_10315	COG1231	oxidoreductase activity
GII81_10320	COG0582	viral genome integration into host DNA
GII81_10375	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_10420	COG3953	SLT domain
GII81_10420	COG5280	Phage tail tape measure protein TP901
GII81_10480	COG1403	HNH endonuclease
GII81_10550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII81_10555	COG2207	Transcriptional regulator
GII81_10555	COG0662	Cupin 2, conserved barrel domain protein
GII81_10560	COG0456	acetyltransferase
GII81_10565	COG1309	transcriptional regulator
GII81_10570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_10575	COG3708	Transcriptional regulator
GII81_10580	COG2378	regulation of single-species biofilm formation
GII81_10590	COG0640	Transcriptional regulator
GII81_10595	COG0741	lytic transglycosylase activity
GII81_10600	COG2322	membrane
GII81_10615	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII81_10620	COG3239	Fatty acid desaturase
GII81_10625	COG4585	Histidine kinase
GII81_10630	COG2197	response regulator
GII81_10635	COG3584	3D domain protein
GII81_10635	COG1388	LysM domain
GII81_10640	COG0514	ATP-dependent DNA helicase (RecQ)
GII81_10650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII81_10655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII81_10670	COG0071	Belongs to the small heat shock protein (HSP20) family
GII81_10695	COG1012	belongs to the aldehyde dehydrogenase family
GII81_10700	COG1657	PFAM Prenyltransferase squalene oxidase
GII81_10705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII81_10710	COG0733	neurotransmitter:sodium symporter activity
GII81_10715	COG0385	Bile acid
GII81_10720	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII81_10725	COG0567	Dehydrogenase, E1 component
GII81_10730	COG4548	von Willebrand factor, type A
GII81_10735	COG0714	Associated with various cellular activities
GII81_10740	COG2032	superoxide dismutase activity
GII81_10745	COG0791	NLP P60 protein
GII81_10745	COG1388	LysM domain
GII81_10750	COG1819	glycosyl
GII81_10755	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII81_10760	COG0534	Mate efflux family protein
GII81_10765	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_10770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII81_10775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII81_10785	COG2962	Rard protein
GII81_10800	COG2610	gluconate transmembrane transporter activity
GII81_10805	COG1942	4-Oxalocrotonate Tautomerase
GII81_10810	COG1733	regulation of RNA biosynthetic process
GII81_10815	COG0778	Nitroreductase
GII81_10820	COG0400	carboxylic ester hydrolase activity
GII81_10825	COG0346	lactoylglutathione lyase activity
GII81_10835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII81_10840	COG3409	Peptidoglycan-binding domain 1 protein
GII81_10840	COG0793	Belongs to the peptidase S41A family
GII81_10845	COG2226	methyltransferase
GII81_10855	COG1876	peptidase activity
GII81_10860	COG0813	purine-nucleoside phosphorylase activity
GII81_10875	COG0671	phosphoesterase, PA-phosphatase related
GII81_10895	COG4479	Belongs to the UPF0346 family
GII81_10905	COG1509	lysine 2,3-aminomutase activity
GII81_10910	COG0456	acetyltransferase
GII81_10915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII81_10920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII81_10925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII81_10930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII81_10945	COG0456	acetyltransferase
GII81_10950	COG0463	Glycosyl transferase, family 2
GII81_10965	COG4641	Protein conserved in bacteria
GII81_10970	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII81_10975	COG1086	Polysaccharide biosynthesis protein
GII81_10980	COG3331	DNA recombination
GII81_11075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_11080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII81_11100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII81_11100	COG1372	Participates in initiation and elongation during chromosome replication
GII81_11105	COG1780	Probably involved in ribonucleotide reductase function
GII81_11195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII81_11210	COG3584	3D domain protein
GII81_11215	COG0587	DNA-directed DNA polymerase activity
GII81_11220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII81_11225	COG0358	DNA primase activity
GII81_11230	COG0305	Participates in initiation and elongation during chromosome replication
GII81_11240	COG2887	Belongs to the helicase family. UvrD subfamily
GII81_11270	COG5434	Belongs to the glycosyl hydrolase 28 family
GII81_11270	COG3420	alginic acid biosynthetic process
GII81_11275	COG4195	phage-related replication protein
GII81_11295	COG2135	peptidase activity
GII81_11300	COG1793	dna ligase
GII81_11390	COG3645	SOS response
GII81_11390	COG3646	Phage regulatory protein
GII81_11425	COG3655	Transcriptional regulator
GII81_11510	COG3655	Transcriptional regulator
GII81_11585	COG0776	regulation of translation
GII81_11615	COG4373	Mu-like prophage FluMu protein gp28
GII81_11715	COG0582	viral genome integration into host DNA
GII81_11720	COG1396	sequence-specific DNA binding
GII81_11730	COG1196	nuclear chromosome segregation
GII81_11730	COG0741	lytic transglycosylase activity
GII81_11730	COG0739	heme binding
GII81_11740	COG2433	Pfam Transposase IS66
GII81_11755	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_11770	COG0457	Tetratricopeptide repeat
GII81_11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_11785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII81_11790	COG2226	methyltransferase
GII81_11795	COG2211	Major facilitator Superfamily
GII81_11800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII81_11840	COG5444	nuclease activity
GII81_11845	COG4282	regulation of fungal-type cell wall biogenesis
GII81_11855	COG1525	nuclease
GII81_11875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII81_11880	COG1086	Polysaccharide biosynthesis protein
GII81_11885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII81_11890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII81_11895	COG1846	Transcriptional regulator
GII81_11900	COG0534	Mate efflux family protein
GII81_11910	COG4698	Protein conserved in bacteria
GII81_11915	COG2755	lipolytic protein G-D-S-L family
GII81_11920	COG1999	signal sequence binding
GII81_11930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII81_11935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII81_11940	COG1272	protein, Hemolysin III
GII81_11945	COG0204	Acyl-transferase
GII81_11950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII81_11955	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII81_11960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII81_11970	COG2136	Putative SAM-dependent methyltransferase
GII81_11970	COG2521	methyltransferase
GII81_11980	COG0129	dihydroxy-acid dehydratase activity
GII81_11985	COG1413	lyase activity
GII81_11990	COG1418	mRNA catabolic process
GII81_11995	COG0386	Belongs to the glutathione peroxidase family
GII81_12000	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII81_12005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII81_12015	COG1278	Cold shock
GII81_12035	COG0328	RNA-DNA hybrid ribonuclease activity
GII81_12040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII81_12045	COG0328	RNA-DNA hybrid ribonuclease activity
GII81_12055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII81_12070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII81_12080	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII81_12085	COG3424	synthase
GII81_12090	COG2233	PERMEase
GII81_12095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII81_12100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII81_12110	COG0800	Aldolase
GII81_12115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII81_12120	COG1609	Transcriptional regulator
GII81_12125	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII81_12130	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_12135	COG1199	ATP-dependent helicase activity
GII81_12150	COG0116	Belongs to the methyltransferase superfamily
GII81_12165	COG4474	Belongs to the UPF0398 family
GII81_12180	COG3359	exonuclease
GII81_12185	COG1205	dead DEAH box helicase
GII81_12185	COG1111	helicase
GII81_12190	COG2190	(PTS) system
GII81_12195	COG0071	Belongs to the small heat shock protein (HSP20) family
GII81_12230	COG3331	DNA recombination
GII81_12235	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII81_12235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII81_12245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII81_12250	COG3935	DnaD domain protein
GII81_12255	COG0017	Asparaginyl-tRNA synthetase
GII81_12260	COG0436	Aminotransferase
GII81_12265	COG5353	protein conserved in bacteria
GII81_12275	COG1199	ATP-dependent helicase activity
GII81_12275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII81_12280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII81_12285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII81_12290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII81_12295	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII81_12295	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII81_12300	COG0617	tRNA 3'-terminal CCA addition
GII81_12305	COG0438	transferase activity, transferring glycosyl groups
GII81_12310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII81_12315	COG1803	Methylglyoxal synthase
GII81_12320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII81_12325	COG1694	Mazg nucleotide pyrophosphohydrolase
GII81_12330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_12340	COG4347	Protein of unknown function (DUF1405)
GII81_12345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII81_12345	COG2010	Cytochrome c
GII81_12350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII81_12355	COG0723	plastoquinol--plastocyanin reductase activity
GII81_12365	COG5582	Belongs to the UPF0302 family
GII81_12370	COG0457	Tetratricopeptide repeat
GII81_12375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII81_12380	COG0287	Prephenate dehydrogenase
GII81_12390	COG0159	tryptophan synthase activity
GII81_12395	COG0133	tryptophan synthase activity
GII81_12400	COG0135	phosphoribosylanthranilate isomerase activity
GII81_12410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII81_12415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII81_12420	COG4401	Chorismate mutase type I
GII81_12425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII81_12430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII81_12435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII81_12440	COG0105	UTP biosynthetic process
GII81_12445	COG0142	geranyltranstransferase activity
GII81_12450	COG2226	methyltransferase
GII81_12455	COG0142	geranyltranstransferase activity
GII81_12465	COG0302	gtp cyclohydrolase
GII81_12470	COG0776	regulation of translation
GII81_12475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII81_12490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII81_12495	COG1160	GTP binding
GII81_12520	COG1304	FMN binding
GII81_12525	COG0539	negative regulation of cytoplasmic translation
GII81_12530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII81_12540	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII81_12545	COG2959	enzyme of heme biosynthesis
GII81_12550	COG3773	Cell wall hydrolase
GII81_12550	COG3409	Peptidoglycan-binding domain 1 protein
GII81_12555	COG2339	peptidase activity
GII81_12560	COG0492	ferredoxin-NADP+ reductase activity
GII81_12565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII81_12570	COG4862	establishment of competence for transformation
GII81_12575	COG1408	metallophosphoesterase
GII81_12585	COG1388	LysM domain
GII81_12590	COG1266	CAAX protease self-immunity
GII81_12595	COG0514	ATP-dependent DNA helicase (RecQ)
GII81_12600	COG4955	Helix-turn-helix domain
GII81_12605	COG1141	Ferredoxin
GII81_12610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII81_12615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII81_12620	COG0710	3-dehydroquinate dehydratase activity
GII81_12630	COG1595	DNA-templated transcription, initiation
GII81_12635	COG5002	protein histidine kinase activity
GII81_12640	COG0745	RESPONSE REGULATOR receiver
GII81_12645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII81_12650	COG1333	cytochrome c biogenesis protein
GII81_12655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_12660	COG1187	pseudouridine synthase activity
GII81_12665	COG0700	Nucleoside recognition
GII81_12670	COG2715	membrane protein required for spore maturation
GII81_12675	COG1686	Belongs to the peptidase S11 family
GII81_12685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII81_12690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII81_12695	COG1547	Domain of unknown function (DUF309)
GII81_12700	COG0456	acetyltransferase
GII81_12705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII81_12710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII81_12710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII81_12715	COG0307	riboflavin synthase, alpha
GII81_12720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII81_12720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII81_12730	COG0681	Belongs to the peptidase S26 family
GII81_12740	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII81_12765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII81_12770	COG4086	secreted protein
GII81_12775	COG0019	diaminopimelate decarboxylase activity
GII81_12780	COG0697	spore germination
GII81_12795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII81_12815	COG1191	sigma factor activity
GII81_12820	COG2172	sigma factor antagonist activity
GII81_12825	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_12830	COG1686	Belongs to the peptidase S11 family
GII81_12835	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII81_12840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII81_12845	COG4974	Belongs to the 'phage' integrase family
GII81_12855	COG0735	belongs to the Fur family
GII81_12860	COG1300	Membrane
GII81_12870	COG0281	malic enzyme
GII81_12875	COG1757	Na H antiporter
GII81_12880	COG1027	Aspartate ammonia-lyase
GII81_12885	COG0252	asparaginase activity
GII81_12890	COG1396	sequence-specific DNA binding
GII81_12895	COG1379	DNA repair
GII81_12900	COG0494	nUDIX hydrolase
GII81_12910	COG0667	Aldo Keto reductase
GII81_12920	COG1073	alpha beta
GII81_12930	COG4918	Iron-sulphur cluster biosynthesis
GII81_12935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII81_12935	COG0456	acetyltransferase
GII81_12940	COG2329	Antibiotic biosynthesis monooxygenase
GII81_12945	COG0456	acetyltransferase
GII81_12955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII81_12965	COG2211	Major facilitator Superfamily
GII81_12970	COG0346	lactoylglutathione lyase activity
GII81_12975	COG1072	(Pantothenic acid kinase))
GII81_12980	COG3048	D-serine ammonia-lyase activity
GII81_12985	COG0300	oxidoreductase activity
GII81_12990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_12995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII81_13000	COG4187	Peptidase family M20/M25/M40
GII81_13005	COG1902	pentaerythritol trinitrate reductase activity
GII81_13010	COG0596	Alpha beta hydrolase
GII81_13020	COG1234	tRNA 3'-trailer cleavage
GII81_13025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII81_13030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII81_13035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII81_13045	COG0706	membrane insertase activity
GII81_13050	COG3361	conserved protein (COG2071)
GII81_13055	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII81_13060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII81_13065	COG0346	lactoylglutathione lyase activity
GII81_13075	COG1376	ErfK ybiS ycfS ynhG family protein
GII81_13080	COG4129	membrane
GII81_13085	COG1126	abc transporter atp-binding protein
GII81_13090	COG0765	amino acid transport
GII81_13095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_13105	COG1597	lipid kinase activity
GII81_13110	COG2814	Major facilitator Superfamily
GII81_13115	COG4978	Transcriptional regulator
GII81_13115	COG0789	Transcriptional regulator
GII81_13120	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII81_13125	COG0022	dehydrogenase e1 component
GII81_13130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII81_13135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII81_13140	COG3426	butyrate kinase activity
GII81_13145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII81_13150	COG0280	phosphate acetyltransferase
GII81_13155	COG3290	protein histidine kinase activity
GII81_13155	COG3829	transcription factor binding
GII81_13165	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII81_13170	COG2079	MmgE PrpD family protein
GII81_13175	COG0372	Belongs to the citrate synthase family
GII81_13180	COG1960	acyl-CoA dehydrogenase activity
GII81_13185	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII81_13190	COG0183	Belongs to the thiolase family
GII81_13195	COG0584	glycerophosphoryl diester phosphodiesterase
GII81_13200	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_13215	COG1902	pentaerythritol trinitrate reductase activity
GII81_13220	COG0745	RESPONSE REGULATOR receiver
GII81_13225	COG0750	zinc metalloprotease
GII81_13230	COG0497	DNA recombination
GII81_13235	COG1438	arginine binding
GII81_13240	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII81_13245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII81_13250	COG0142	geranyltranstransferase activity
GII81_13255	COG1722	exodeoxyribonuclease VII activity
GII81_13260	COG1570	exodeoxyribonuclease VII activity
GII81_13265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII81_13270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII81_13275	COG1302	Protein conserved in bacteria
GII81_13280	COG0439	Biotin carboxylase
GII81_13285	COG0511	ligase activity, forming carbon-carbon bonds
GII81_13325	COG3854	ATPases associated with a variety of cellular activities
GII81_13335	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII81_13340	COG0006	proline dipeptidase activity
GII81_13345	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII81_13355	COG3872	metal-dependent enzyme
GII81_13365	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII81_13370	COG1321	iron dependent repressor
GII81_13375	COG0095	Lipoate-protein ligase
GII81_13380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII81_13385	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII81_13390	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII81_13395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII81_13400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII81_13415	COG1396	sequence-specific DNA binding
GII81_13425	COG0681	Belongs to the peptidase S26 family
GII81_13450	COG4940	Competence protein ComGF
GII81_13460	COG4970	Tfp pilus assembly protein FimT
GII81_13465	COG4537	Required for transformation and DNA binding
GII81_13470	COG1459	type II secretion system
GII81_13475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII81_13480	COG0517	IMP dehydrogenase activity
GII81_13485	COG0598	Magnesium transport protein CorA
GII81_13490	COG1253	flavin adenine dinucleotide binding
GII81_13495	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_13505	COG1393	Belongs to the ArsC family
GII81_13515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_13525	COG0011	TIGRFAM Protein of
GII81_13535	COG2866	Carboxypeptidase
GII81_13540	COG1368	sulfuric ester hydrolase activity
GII81_13545	COG1940	carbohydrate kinase activity
GII81_13550	COG4483	Protein conserved in bacteria
GII81_13555	COG0457	Tetratricopeptide repeat
GII81_13555	COG0705	Rhomboid family
GII81_13565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII81_13570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII81_13575	COG0438	transferase activity, transferring glycosyl groups
GII81_13590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII81_13595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII81_13600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII81_13605	COG0581	inorganic phosphate transmembrane transporter activity
GII81_13610	COG0573	inorganic phosphate transmembrane transporter activity
GII81_13615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII81_13625	COG0477	Major facilitator Superfamily
GII81_13630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII81_13635	COG2839	Protein conserved in bacteria
GII81_13640	COG5521	maltodextrose utilization protein MalA
GII81_13645	COG1388	LysM domain
GII81_13650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII81_13655	COG4709	membrane
GII81_13660	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII81_13665	COG0735	belongs to the Fur family
GII81_13670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_13680	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII81_13685	COG0513	Belongs to the DEAD box helicase family
GII81_13695	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII81_13700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII81_13705	COG2384	SAM-dependent methyltransferase
GII81_13710	COG2010	Cytochrome c
GII81_13715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII81_13720	COG0358	DNA primase activity
GII81_13725	COG1671	Belongs to the UPF0178 family
GII81_13730	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII81_13735	COG0517	IMP dehydrogenase activity
GII81_13740	COG0751	glycine-tRNA ligase activity
GII81_13745	COG0752	glycyl-tRNA synthetase alpha subunit
GII81_13750	COG1381	Involved in DNA repair and RecF pathway recombination
GII81_13760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII81_13765	COG0295	cytidine deaminase activity
GII81_13770	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII81_13775	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII81_13780	COG1480	7TM receptor with intracellular HD hydrolase
GII81_13785	COG1702	phosphate starvation-inducible protein PhoH
GII81_13790	COG0561	phosphatase activity
GII81_13805	COG4864	UPF0365 protein
GII81_13810	COG1030	water channel activity
GII81_13815	COG1610	YqeY-like protein
GII81_13820	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GII81_13825	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII81_13830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII81_13835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII81_13840	COG2264	protein methyltransferase activity
GII81_13845	COG0484	heat shock protein binding
GII81_13850	COG0443	Heat shock 70 kDa protein
GII81_13855	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII81_13860	COG1420	regulation of RNA biosynthetic process
GII81_13865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII81_13870	COG0481	GTPase activity
GII81_13880	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_13885	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII81_13890	COG0268	Binds directly to 16S ribosomal RNA
GII81_13895	COG1466	dna polymerase III delta subunit
GII81_13910	COG0658	competence protein
GII81_13910	COG2333	competence protein COMEC
GII81_13915	COG2131	deaminase
GII81_13920	COG1555	photosystem II stabilization
GII81_13920	COG1596	polysaccharide export
GII81_13925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII81_13930	COG2226	methyltransferase
GII81_13935	COG0799	negative regulation of ribosome biogenesis
GII81_13940	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII81_13945	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII81_13950	COG1534	Rna-binding protein
GII81_13955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII81_13960	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII81_13965	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII81_13975	COG2755	lipolytic protein G-D-S-L family
GII81_13980	COG3409	Peptidoglycan-binding domain 1 protein
GII81_13980	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_13985	COG0398	Pfam SNARE associated Golgi protein
GII81_14000	COG3209	COG3209 Rhs family protein
GII81_14010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII81_14015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII81_14020	COG0798	PFAM Bile acid sodium symporter
GII81_14025	COG0346	lactoylglutathione lyase activity
GII81_14030	COG0640	Transcriptional regulator
GII81_14035	COG3403	YqcI/YcgG family
GII81_14055	COG0604	alcohol dehydrogenase
GII81_14080	COG0457	Tetratricopeptide repeat
GII81_14095	COG5444	nuclease activity
GII81_14120	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_14120	COG3409	Peptidoglycan-binding domain 1 protein
GII81_14125	COG4824	toxin secretion phage lysis holin
GII81_14155	COG3778	Protein conserved in bacteria
GII81_14160	COG3299	homolog of phage Mu protein gp47
GII81_14165	COG3628	GPW Gp25 family protein
GII81_14175	COG4193	domain, Protein
GII81_14180	COG1652	LysM domain
GII81_14185	COG3953	SLT domain
GII81_14185	COG5280	Phage tail tape measure protein TP901
GII81_14245	COG4653	Phage capsid family
GII81_14250	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII81_14260	COG2369	cell adhesion
GII81_14265	COG5518	Phage portal protein
GII81_14270	COG1783	phage Terminase large subunit
GII81_14275	COG5484	DNA packaging
GII81_14285	COG1335	isochorismatase
GII81_14320	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GII81_14330	COG1484	DNA-dependent DNA replication
GII81_14335	COG3935	DnaD domain protein
GII81_14340	COG3723	Recombinational DNA repair protein, rece pathway
GII81_14345	COG5377	YqaJ viral recombinase family
GII81_14380	COG3620	sequence-specific DNA binding
GII81_14390	COG0563	adenylate kinase activity
GII81_14395	COG2856	Zn peptidase
GII81_14410	COG0642	Histidine kinase
GII81_14410	COG5002	protein histidine kinase activity
GII81_14415	COG0745	RESPONSE REGULATOR receiver
GII81_14420	COG2311	Membrane
GII81_14430	COG0454	-acetyltransferase
GII81_14435	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII81_14445	COG0730	response to heat
GII81_14450	COG0425	Belongs to the sulfur carrier protein TusA family
GII81_14455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_14455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII81_14465	COG0425	Belongs to the sulfur carrier protein TusA family
GII81_14465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII81_14475	COG1937	Protein conserved in bacteria
GII81_14480	COG0662	Cupin 2, conserved barrel domain protein
GII81_14490	COG0789	Transcriptional regulator
GII81_14490	COG4978	Transcriptional regulator
GII81_14495	COG2814	Major facilitator Superfamily
GII81_14500	COG0456	acetyltransferase
GII81_14505	COG1253	flavin adenine dinucleotide binding
GII81_14515	COG0697	spore germination
GII81_14520	COG0583	DNA-binding transcription factor activity
GII81_14525	COG2072	flavoprotein involved in K transport
GII81_14530	COG1230	cation diffusion facilitator family transporter
GII81_14535	COG1942	4-Oxalocrotonate Tautomerase
GII81_14540	COG0583	DNA-binding transcription factor activity
GII81_14550	COG1114	Component of the transport system for branched-chain amino acids
GII81_14555	COG1687	branched-chain amino acid
GII81_14560	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII81_14565	COG1522	sequence-specific DNA binding
GII81_14575	COG2124	cytochrome p450
GII81_14580	COG1335	isochorismatase
GII81_14590	COG2318	DinB family
GII81_14600	COG2070	2-Nitropropane dioxygenase
GII81_14605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII81_14615	COG2186	Transcriptional regulator
GII81_14630	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_14635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII81_14640	COG3959	Transketolase, thiamine diphosphate binding domain
GII81_14650	COG0789	Transcriptional regulator
GII81_14650	COG4978	Transcriptional regulator
GII81_14655	COG2315	Protein conserved in bacteria
GII81_14665	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII81_14670	COG1595	DNA-templated transcription, initiation
GII81_14675	COG0667	Aldo Keto reductase
GII81_14680	COG2851	Citrate transporter
GII81_14685	COG0583	DNA-binding transcription factor activity
GII81_14690	COG2828	Protein conserved in bacteria
GII81_14695	COG3409	Peptidoglycan-binding domain 1 protein
GII81_14700	COG5566	PFAM Mor transcription activator
GII81_14705	COG0596	Alpha beta hydrolase
GII81_14710	COG4991	sh3 domain protein
GII81_14715	COG4991	sh3 domain protein
GII81_14725	COG0346	lactoylglutathione lyase activity
GII81_14735	COG5577	PFAM Coat F domain
GII81_14740	COG1063	alcohol dehydrogenase
GII81_14750	COG5577	PFAM Coat F domain
GII81_14755	COG0789	Transcriptional regulator
GII81_14765	COG1064	alcohol dehydrogenase
GII81_14770	COG0693	protein deglycase activity
GII81_14775	COG1621	beta-fructofuranosidase activity
GII81_14780	COG3716	PTS system mannose fructose sorbose family IID component
GII81_14785	COG3715	PTS system
GII81_14790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_14795	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_14800	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII81_14800	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII81_14810	COG1113	amino acid transport
GII81_14815	COG1280	lysine exporter protein (LysE YggA)
GII81_14820	COG1378	Sugar-specific transcriptional regulator TrmB
GII81_14825	COG1595	DNA-templated transcription, initiation
GII81_14845	COG2124	cytochrome p450
GII81_14845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII81_14850	COG1309	transcriptional regulator
GII81_14855	COG2226	methyltransferase
GII81_14870	COG2116	formate transmembrane transporter activity
GII81_14875	COG5609	conserved protein (DUF2294)
GII81_14880	COG3383	formate dehydrogenase (NAD+) activity
GII81_14885	COG2427	Protein of unknown function (DUF1641)
GII81_14895	COG0626	cystathionine gamma-synthase activity
GII81_14900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII81_14905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII81_14910	COG2226	methyltransferase
GII81_14925	COG0768	penicillin binding
GII81_14930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII81_14935	COG0572	uridine kinase
GII81_14955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII81_14960	COG3906	Belongs to the UPF0473 family
GII81_14965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII81_14970	COG4472	Bacterial protein of unknown function (DUF965)
GII81_14975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII81_14980	COG0628	permease
GII81_14985	COG1126	abc transporter atp-binding protein
GII81_14990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_14995	COG0765	amino acid transport
GII81_15000	COG0765	amino acid transport
GII81_15015	COG3881	PFAM PRC-barrel domain
GII81_15020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII81_15025	COG0457	Tetratricopeptide repeat
GII81_15030	COG0482	sulfurtransferase activity
GII81_15035	COG1104	cysteine desulfurase activity
GII81_15040	COG1959	2 iron, 2 sulfur cluster binding
GII81_15045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII81_15050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII81_15060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII81_15065	COG0124	histidyl-tRNA synthetase
GII81_15075	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_15075	COG3103	Sh3 type 3 domain protein
GII81_15075	COG4991	sh3 domain protein
GII81_15080	COG1490	D-aminoacyl-tRNA deacylase activity
GII81_15085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII81_15090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII81_15095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII81_15095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII81_15100	COG5416	Lipopolysaccharide assembly protein A domain
GII81_15105	COG0490	domain, Protein
GII81_15110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII81_15110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII81_15120	COG2244	polysaccharide biosynthetic process
GII81_15125	COG2323	membrane
GII81_15135	COG1862	Preprotein translocase
GII81_15140	COG0343	queuine tRNA-ribosyltransferase activity
GII81_15145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII81_15155	COG2255	four-way junction helicase activity
GII81_15160	COG0632	four-way junction helicase activity
GII81_15170	COG2814	Major facilitator Superfamily
GII81_15175	COG0673	inositol 2-dehydrogenase activity
GII81_15180	COG2112	serine threonine protein kinase
GII81_15200	COG1115	amino acid carrier protein
GII81_15205	COG0217	transcriptional regulatory protein
GII81_15215	COG1388	LysM domain
GII81_15220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII81_15225	COG0157	Belongs to the NadC ModD family
GII81_15230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII81_15235	COG1104	cysteine desulfurase activity
GII81_15240	COG1827	regulation of RNA biosynthetic process
GII81_15245	COG0077	Prephenate dehydratase
GII81_15250	COG4492	Belongs to the UPF0735 family
GII81_15255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII81_15260	COG3290	protein histidine kinase activity
GII81_15270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII81_15275	COG2868	ribosomal protein
GII81_15280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII81_15285	COG1994	Peptidase M50
GII81_15290	COG0739	heme binding
GII81_15295	COG2894	cell division
GII81_15300	COG0850	regulation of cytokinetic process
GII81_15305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII81_15310	COG1792	Involved in formation and maintenance of cell shape
GII81_15315	COG1077	Cell shape determining protein MreB Mrl
GII81_15320	COG2003	Belongs to the UPF0758 family
GII81_15325	COG0424	maF-like protein
GII81_15335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII81_15340	COG0285	dihydrofolate synthase activity
GII81_15345	COG0525	valine-tRNA ligase activity
GII81_15355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII81_15360	COG1388	LysM domain
GII81_15365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII81_15370	COG0113	porphobilinogen synthase activity
GII81_15375	COG1587	Uroporphyrinogen-III synthase
GII81_15380	COG0181	hydroxymethylbilane synthase activity
GII81_15385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII81_15390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII81_15400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII81_15405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII81_15410	COG1067	ATP-dependent peptidase activity
GII81_15410	COG0470	DNA polymerase III
GII81_15415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII81_15420	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII81_15425	COG0457	Tetratricopeptide repeat
GII81_15425	COG1477	protein flavinylation
GII81_15430	COG0066	3-isopropylmalate dehydratase activity
GII81_15435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII81_15440	COG0473	3-isopropylmalate dehydrogenase activity
GII81_15445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII81_15450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII81_15455	COG0440	acetolactate synthase activity
GII81_15460	COG0028	Belongs to the TPP enzyme family
GII81_15470	COG0454	-acetyltransferase
GII81_15475	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII81_15485	COG0622	Phosphoesterase
GII81_15490	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII81_15495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII81_15500	COG5401	PFAM Sporulation and spore germination
GII81_15505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII81_15510	COG1846	Transcriptional regulator
GII81_15515	COG2197	response regulator
GII81_15520	COG0824	Thioesterase
GII81_15525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII81_15530	COG1053	succinate dehydrogenase
GII81_15535	COG2009	succinate dehydrogenase
GII81_15540	COG1719	4-vinyl reductase, 4VR
GII81_15545	COG0527	aspartate kinase activity
GII81_15550	COG0322	excinuclease ABC activity
GII81_15555	COG3118	belongs to the thioredoxin family
GII81_15560	COG3534	alpha-L-arabinofuranosidase
GII81_15565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII81_15570	COG2086	electron transfer activity
GII81_15575	COG1024	Enoyl-CoA hydratase
GII81_15580	COG1309	transcriptional regulator
GII81_15585	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_15590	COG3766	membrane
GII81_15595	COG1193	negative regulation of DNA recombination
GII81_15600	COG1796	DNA polymerase
GII81_15600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII81_15605	COG1286	toxin biosynthetic process
GII81_15610	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII81_15615	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII81_15620	COG0072	phenylalanine-tRNA ligase activity
GII81_15620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII81_15625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII81_15635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII81_15645	COG3835	regulator
GII81_15650	COG0277	FAD linked oxidase domain protein
GII81_15655	COG0247	lactate metabolic process
GII81_15670	COG1966	Carbon starvation protein
GII81_15675	COG3534	alpha-L-arabinofuranosidase
GII81_15680	COG0395	ABC-type sugar transport system, permease component
GII81_15685	COG1175	transmembrane transport
GII81_15690	COG1653	transport
GII81_15695	COG0371	Dehydrogenase
GII81_15700	COG0647	UMP catabolic process
GII81_15705	COG0235	Class ii aldolase
GII81_15710	COG1069	ribulokinase activity
GII81_15715	COG2160	L-arabinose isomerase activity
GII81_15720	COG3507	Belongs to the glycosyl hydrolase 43 family
GII81_15725	COG1363	Peptidase, m42
GII81_15735	COG3326	Membrane
GII81_15740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII81_15745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII81_15750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII81_15760	COG1346	cytolysis
GII81_15765	COG1380	Effector of murein hydrolase LrgA
GII81_15770	COG3279	Response regulator of the LytR AlgR family
GII81_15775	COG3275	phosphorelay sensor kinase activity
GII81_15785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII81_15795	COG0398	Pfam SNARE associated Golgi protein
GII81_15800	COG1484	DNA-dependent DNA replication
GII81_15805	COG3611	Membrane attachment protein
GII81_15810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII81_15815	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII81_15820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII81_15825	COG1733	regulation of RNA biosynthetic process
GII81_15830	COG2814	Major facilitator Superfamily
GII81_15835	COG0656	L-ascorbic acid biosynthetic process
GII81_15840	COG0237	dephospho-CoA kinase activity
GII81_15845	COG1971	Probably functions as a manganese efflux pump
GII81_15850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII81_15855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII81_15855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII81_15860	COG5002	protein histidine kinase activity
GII81_15865	COG0745	RESPONSE REGULATOR receiver
GII81_15870	COG0039	L-malate dehydrogenase activity
GII81_15875	COG0538	isocitrate dehydrogenase activity
GII81_15880	COG0372	Belongs to the citrate synthase family
GII81_15885	COG2707	UPF0756 membrane protein
GII81_15890	COG0628	permease
GII81_15895	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII81_15900	COG0469	pyruvate kinase activity
GII81_15905	COG0205	6-phosphofructokinase activity
GII81_15910	COG0825	malonyl-CoA metabolic process
GII81_15915	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII81_15920	COG0281	malic enzyme
GII81_15925	COG0587	DNA-directed DNA polymerase activity
GII81_15945	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII81_15955	COG4109	DRTGG domain
GII81_15960	COG0730	response to heat
GII81_15965	COG1473	amidohydrolase
GII81_15970	COG0196	riboflavin kinase activity
GII81_15975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_15980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII81_15985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_15990	COG1126	abc transporter atp-binding protein
GII81_15995	COG0765	amino acid transport
GII81_16000	COG0765	amino acid transport
GII81_16005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_16010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_16015	COG0454	-acetyltransferase
GII81_16020	COG0583	DNA-binding transcription factor activity
GII81_16025	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII81_16030	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_16040	COG0165	Argininosuccinate lyase
GII81_16045	COG0137	argininosuccinate synthase activity
GII81_16050	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII81_16055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII81_16065	COG0827	DNA restriction-modification system
GII81_16070	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII81_16075	COG3874	Sporulation protein YtfJ
GII81_16085	COG1714	RDD family
GII81_16090	COG0616	signal peptide processing
GII81_16095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII81_16100	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII81_16105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII81_16115	COG0301	tRNA thio-modification
GII81_16120	COG1104	cysteine desulfurase activity
GII81_16125	COG1114	Component of the transport system for branched-chain amino acids
GII81_16130	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII81_16135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII81_16140	COG1309	transcriptional regulator
GII81_16145	COG1956	GAF domain-containing protein
GII81_16150	COG2203	Gaf domain
GII81_16150	COG2199	diguanylate cyclase activity
GII81_16160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII81_16165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII81_16170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII81_16175	COG0454	-acetyltransferase
GII81_16180	COG0517	IMP dehydrogenase activity
GII81_16185	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII81_16190	COG1360	Flagellar Motor Protein
GII81_16195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII81_16200	COG1609	Transcriptional regulator
GII81_16205	COG1605	Chorismate mutase
GII81_16205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII81_16210	COG3118	belongs to the thioredoxin family
GII81_16215	COG4980	gas vesicle protein
GII81_16220	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII81_16225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII81_16230	COG1674	ftsk spoiiie
GII81_16235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII81_16240	COG4848	Belongs to the UPF0354 family
GII81_16245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_16260	COG1363	Peptidase, m42
GII81_16265	COG5584	Small secreted protein
GII81_16270	COG0281	malic enzyme
GII81_16275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_16280	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII81_16290	COG0510	thiamine kinase activity
GII81_16295	COG1523	belongs to the glycosyl hydrolase 13 family
GII81_16300	COG1597	lipid kinase activity
GII81_16310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII81_16315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII81_16320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII81_16325	COG2252	PERMEase
GII81_16330	COG4473	ABC transporter
GII81_16335	COG1131	(ABC) transporter
GII81_16340	COG1349	DNA-binding transcription factor activity
GII81_16345	COG1187	pseudouridine synthase activity
GII81_16350	COG2244	polysaccharide biosynthetic process
GII81_16355	COG2081	HI0933 family
GII81_16360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII81_16370	COG5578	integral membrane protein
GII81_16375	COG0673	inositol 2-dehydrogenase activity
GII81_16380	COG1653	transport
GII81_16385	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII81_16390	COG4209	transmembrane transport
GII81_16395	COG2207	Transcriptional regulator
GII81_16400	COG1653	transport
GII81_16405	COG0395	ABC-type sugar transport system, permease component
GII81_16410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII81_16415	COG2124	cytochrome p450
GII81_16420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII81_16430	COG0156	8-amino-7-oxononanoate synthase activity
GII81_16435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII81_16445	COG1073	alpha beta
GII81_16470	COG1486	melibiose metabolic process
GII81_16475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII81_16480	COG0495	leucyl-tRNA aminoacylation
GII81_16490	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_16490	COG2202	Pas domain
GII81_16495	COG2814	Major facilitator Superfamily
GII81_16500	COG2433	Pfam Transposase IS66
GII81_16505	COG0577	efflux transmembrane transporter activity
GII81_16510	COG1136	(ABC) transporter
GII81_16515	COG2205	protein histidine kinase activity
GII81_16520	COG0745	RESPONSE REGULATOR receiver
GII81_16525	COG0577	efflux transmembrane transporter activity
GII81_16530	COG1136	(ABC) transporter
GII81_16545	COG1131	(ABC) transporter
GII81_16550	COG1725	Transcriptional regulator
GII81_16565	COG1242	4 iron, 4 sulfur cluster binding
GII81_16570	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII81_16580	COG2267	carboxylic ester hydrolase activity
GII81_16585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII81_16590	COG1113	amino acid transport
GII81_16595	COG0367	asparagine synthase
GII81_16600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII81_16605	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII81_16615	COG1506	peptidase
GII81_16620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII81_16625	COG1116	anion transmembrane transporter activity
GII81_16630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII81_16635	COG0494	nUDIX hydrolase
GII81_16640	COG4824	toxin secretion phage lysis holin
GII81_16645	COG0783	Belongs to the Dps family
GII81_16660	COG1854	S-ribosylhomocysteine lyase activity
GII81_16665	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII81_16670	COG0288	reversible hydration of carbon dioxide
GII81_16675	COG0254	rRNA binding
GII81_16680	COG1271	oxidase subunit
GII81_16685	COG1294	oxidase, subunit
GII81_16695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII81_16700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII81_16700	COG1321	iron dependent repressor
GII81_16705	COG1121	(ABC) transporter
GII81_16710	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII81_16715	COG4948	Mandelate Racemase Muconate Lactonizing
GII81_16720	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_16725	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII81_16730	COG0596	Alpha beta hydrolase
GII81_16735	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII81_16740	COG1169	isochorismate synthase
GII81_16745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII81_16750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII81_16755	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII81_16760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII81_16765	COG0438	transferase activity, transferring glycosyl groups
GII81_16775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII81_16780	COG0438	transferase activity, transferring glycosyl groups
GII81_16785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII81_16790	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GII81_16795	COG0058	SHG alpha-glucan phosphorylase activity
GII81_16800	COG0297	glycogen (starch) synthase activity
GII81_16805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII81_16810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII81_16815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII81_16940	COG3859	Proton-coupled thiamine transporter YuaJ
GII81_16945	COG1247	-acetyltransferase
GII81_16950	COG2268	Band 7 protein
GII81_16955	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII81_16960	COG2318	DinB family
GII81_16970	COG1454	alcohol dehydrogenase
GII81_16980	COG1510	regulation of RNA biosynthetic process
GII81_16990	COG0569	domain protein
GII81_16995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII81_17000	COG4682	membrane
GII81_17005	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII81_17010	COG0477	Major facilitator Superfamily
GII81_17015	COG5553	Cysteine dioxygenase type I
GII81_17025	COG1968	undecaprenyl-diphosphatase activity
GII81_17030	COG0628	permease
GII81_17035	COG0673	inositol 2-dehydrogenase activity
GII81_17040	COG4806	L-rhamnose isomerase
GII81_17045	COG3254	rhamnose metabolic process
GII81_17050	COG1070	Carbohydrate kinase
GII81_17055	COG1349	DNA-binding transcription factor activity
GII81_17060	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_17060	COG3347	Dehydrogenase
GII81_17065	COG0840	transmembrane signaling receptor activity
GII81_17070	COG0840	transmembrane signaling receptor activity
GII81_17075	COG0840	transmembrane signaling receptor activity
GII81_17080	COG0840	transmembrane signaling receptor activity
GII81_17100	COG0432	Pfam Uncharacterised protein family UPF0047
GII81_17110	COG0366	Alpha amylase catalytic
GII81_17115	COG1253	flavin adenine dinucleotide binding
GII81_17120	COG2738	Putative neutral zinc metallopeptidase
GII81_17135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII81_17150	COG0166	Belongs to the GPI family
GII81_17155	COG1979	alcohol dehydrogenase
GII81_17160	COG1979	alcohol dehydrogenase
GII81_17165	COG2155	Conserved Protein
GII81_17170	COG1098	S1 RNA binding domain
GII81_17175	COG0436	Aminotransferase
GII81_17180	COG1522	sequence-specific DNA binding
GII81_17185	COG2267	carboxylic ester hydrolase activity
GII81_17195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII81_17200	COG2205	protein histidine kinase activity
GII81_17210	COG5018	Exonuclease
GII81_17220	COG2814	Major facilitator Superfamily
GII81_17225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII81_17230	COG3011	Protein conserved in bacteria
GII81_17240	COG3290	protein histidine kinase activity
GII81_17245	COG4565	transcriptional regulatory protein
GII81_17270	COG3493	citrate carrier protein
GII81_17280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII81_17280	COG2111	Na H antiporter
GII81_17285	COG2111	Na H antiporter
GII81_17290	COG1006	Multisubunit Na H antiporter MnhC subunit
GII81_17295	COG0651	ATP synthesis coupled electron transport
GII81_17300	COG1863	multisubunit Na H antiporter MnhE subunit
GII81_17305	COG2212	antiporter activity
GII81_17310	COG1320	monovalent cation:proton antiporter activity
GII81_17315	COG2050	protein possibly involved in aromatic compounds catabolism
GII81_17320	COG2197	response regulator
GII81_17325	COG4585	Histidine kinase
GII81_17335	COG0142	geranyltranstransferase activity
GII81_17355	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII81_17360	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII81_17365	COG1335	isochorismatase
GII81_17370	COG5506	Protein of unknown function (DUF1694)
GII81_17385	COG0628	permease
GII81_17400	COG1418	mRNA catabolic process
GII81_17405	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_17415	COG1511	domain protein
GII81_17420	COG0433	COG0433 Predicted ATPase
GII81_17420	COG1674	ftsk spoiiie
GII81_17425	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII81_17430	COG5417	Belongs to the EsaB family
GII81_17435	COG4842	Belongs to the WXG100 family
GII81_17440	COG2508	Transcriptional regulator
GII81_17440	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII81_17445	COG0686	Belongs to the AlaDH PNT family
GII81_17450	COG5634	Uncharacterized conserved protein (DUF2278)
GII81_17455	COG3251	PFAM MbtH domain protein
GII81_17460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_17465	COG1535	isochorismatase
GII81_17465	COG3433	isochorismatase activity
GII81_17470	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII81_17475	COG1169	isochorismate synthase
GII81_17480	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_17485	COG2819	hydrolase of the alpha beta superfamily
GII81_17490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII81_17495	COG1268	BioY protein
GII81_17500	COG2056	Na+-H+ antiporter family
GII81_17505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII81_17510	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII81_17515	COG3584	3D domain protein
GII81_17530	COG1252	NADH dehydrogenase
GII81_17535	COG0492	ferredoxin-NADP+ reductase activity
GII81_17545	COG0516	GMP reductase activity
GII81_17550	COG2808	Putative FMN-binding domain
GII81_17555	COG0456	acetyltransferase
GII81_17560	COG0316	Belongs to the HesB IscA family
GII81_17565	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII81_17570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII81_17575	COG4844	belongs to the
GII81_17580	COG1252	NADH dehydrogenase
GII81_17585	COG4837	Protein of unknown function (DUF1462)
GII81_17590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII81_17595	COG4946	Tricorn protease homolog
GII81_17595	COG1506	peptidase
GII81_17595	COG0823	Involved in the tonB-independent uptake of proteins
GII81_17600	COG0083	homoserine kinase activity
GII81_17605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII81_17610	COG0460	homoserine dehydrogenase
GII81_17615	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII81_17620	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII81_17625	COG0647	UMP catabolic process
GII81_17630	COG2445	Protein of unknown function DUF86
GII81_17635	COG4470	Protein conserved in bacteria
GII81_17645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII81_17650	COG0739	heme binding
GII81_17660	COG3377	Domain of unknown function (DUF1805)
GII81_17665	COG0737	Belongs to the 5'-nucleotidase family
GII81_17670	COG0730	response to heat
GII81_17675	COG1801	Protein of unknown function DUF72
GII81_17685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII81_17690	COG2508	Transcriptional regulator
GII81_17695	COG2233	PERMEase
GII81_17700	COG2233	PERMEase
GII81_17705	COG3195	allantoin biosynthetic process
GII81_17705	COG3648	Uricase
GII81_17710	COG2351	hydroxyisourate hydrolase activity
GII81_17720	COG2080	2 iron, 2 sulfur cluster binding
GII81_17725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII81_17730	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII81_17735	COG2068	MobA-Related Protein
GII81_17740	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII81_17745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII81_17750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII81_17760	COG2356	endonuclease I
GII81_17765	COG3842	ATPase activity
GII81_17770	COG2188	Transcriptional regulator
GII81_17775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII81_17780	COG0395	ABC-type sugar transport system, permease component
GII81_17785	COG1175	transmembrane transport
GII81_17790	COG1653	transport
GII81_17795	COG2222	sugar isomerase
GII81_17800	COG0322	excinuclease ABC activity
GII81_17805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII81_17820	COG0719	Fe-S assembly protein
GII81_17825	COG0822	iron-sulfur transferase activity
GII81_17830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII81_17835	COG0719	Fe-S assembly protein
GII81_17840	COG0396	ATPase activity
GII81_17850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII81_17855	COG1464	Belongs to the NlpA lipoprotein family
GII81_17860	COG2011	ABC-type metal ion transport system permease component
GII81_17865	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII81_17875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_17880	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII81_17890	COG0509	glycine decarboxylation via glycine cleavage system
GII81_17895	COG1393	Belongs to the ArsC family
GII81_17900	COG1960	acyl-CoA dehydrogenase activity
GII81_17905	COG0183	Belongs to the thiolase family
GII81_17910	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII81_17910	COG1024	Enoyl-CoA hydratase
GII81_17920	COG0506	proline dehydrogenase activity
GII81_17930	COG5577	PFAM Coat F domain
GII81_17935	COG1846	Transcriptional regulator
GII81_17940	COG0477	Major facilitator Superfamily
GII81_17945	COG1942	4-Oxalocrotonate Tautomerase
GII81_17950	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_17955	COG0583	DNA-binding transcription factor activity
GII81_17965	COG1120	ATPase activity
GII81_17980	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_17985	COG0783	Belongs to the Dps family
GII81_17990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII81_17995	COG0745	RESPONSE REGULATOR receiver
GII81_18000	COG2770	Histidine kinase
GII81_18000	COG2205	protein histidine kinase activity
GII81_18010	COG1309	transcriptional regulator
GII81_18015	COG0114	fumarate hydratase activity
GII81_18025	COG0697	spore germination
GII81_18030	COG0814	amino acid
GII81_18040	COG2197	response regulator
GII81_18045	COG4585	Histidine kinase
GII81_18050	COG4758	membrane
GII81_18055	COG3595	metallopeptidase activity
GII81_18060	COG1842	Phage shock protein A
GII81_18065	COG4758	membrane
GII81_18070	COG2814	Major facilitator Superfamily
GII81_18075	COG2096	Adenosyltransferase
GII81_18080	COG1120	ATPase activity
GII81_18085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_18090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_18095	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_18100	COG3386	PFAM SMP-30 Gluconolaconase
GII81_18105	COG2205	protein histidine kinase activity
GII81_18110	COG0745	RESPONSE REGULATOR receiver
GII81_18120	COG1191	sigma factor activity
GII81_18130	COG2140	Oxalate decarboxylase
GII81_18140	COG0577	efflux transmembrane transporter activity
GII81_18145	COG1136	(ABC) transporter
GII81_18150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII81_18155	COG1120	ATPase activity
GII81_18160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_18165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_18170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_18175	COG0531	amino acid
GII81_18185	COG1988	membrane-bound metal-dependent
GII81_18190	COG1368	sulfuric ester hydrolase activity
GII81_18195	COG1910	domain protein
GII81_18200	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII81_18205	COG4149	molybdate abc transporter
GII81_18210	COG0656	L-ascorbic acid biosynthetic process
GII81_18220	COG0025	NhaP-type Na H and K H
GII81_18225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII81_18230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII81_18235	COG3973	AAA domain
GII81_18245	COG2860	membrane
GII81_18250	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII81_18255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII81_18260	COG2217	Heavy metal translocating P-type atpase
GII81_18265	COG2217	Heavy metal translocating P-type atpase
GII81_18270	COG2608	mercury ion transmembrane transporter activity
GII81_18275	COG1937	Protein conserved in bacteria
GII81_18280	COG0673	inositol 2-dehydrogenase activity
GII81_18285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII81_18290	COG1289	transmembrane transporter activity
GII81_18300	COG2076	Multidrug Resistance protein
GII81_18305	COG1309	transcriptional regulator
GII81_18310	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_18320	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII81_18325	COG0557	exoribonuclease II activity
GII81_18330	COG1647	Serine aminopeptidase, S33
GII81_18335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII81_18340	COG0596	Alpha beta hydrolase
GII81_18345	COG1476	TRANSCRIPTIONal
GII81_18350	COG1396	sequence-specific DNA binding
GII81_18355	COG1396	sequence-specific DNA binding
GII81_18360	COG1733	regulation of RNA biosynthetic process
GII81_18365	COG0840	transmembrane signaling receptor activity
GII81_18370	COG1174	glycine betaine transport
GII81_18375	COG1732	Glycine betaine
GII81_18380	COG1174	glycine betaine transport
GII81_18385	COG0517	IMP dehydrogenase activity
GII81_18385	COG1125	glycine betaine transport
GII81_18390	COG1510	regulation of RNA biosynthetic process
GII81_18395	COG1174	glycine betaine transport
GII81_18400	COG1732	Glycine betaine
GII81_18405	COG1174	glycine betaine transport
GII81_18410	COG1125	glycine betaine transport
GII81_18410	COG0517	IMP dehydrogenase activity
GII81_18415	COG1510	regulation of RNA biosynthetic process
GII81_18420	COG2095	MarC family integral membrane protein
GII81_18430	COG3064	Membrane
GII81_18435	COG4640	response to antibiotic
GII81_18440	COG0456	acetyltransferase
GII81_18445	COG0148	phosphopyruvate hydratase activity
GII81_18450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII81_18455	COG0149	triose-phosphate isomerase activity
GII81_18460	COG0126	phosphoglycerate kinase activity
GII81_18465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII81_18470	COG2390	Transcriptional regulator
GII81_18475	COG2814	Major facilitator Superfamily
GII81_18480	COG1609	Transcriptional regulator
GII81_18485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_18495	COG0583	DNA-binding transcription factor activity
GII81_18500	COG0697	spore germination
GII81_18505	COG1113	amino acid transport
GII81_18510	COG3858	chitin binding
GII81_18515	COG1556	Lactate utilization protein
GII81_18520	COG1139	Iron-sulfur cluster binding protein
GII81_18525	COG0247	lactate metabolic process
GII81_18530	COG2197	response regulator
GII81_18535	COG4585	Histidine kinase
GII81_18540	COG0842	Transport permease protein
GII81_18545	COG1131	(ABC) transporter
GII81_18550	COG0596	Alpha beta hydrolase
GII81_18555	COG2208	phosphoserine phosphatase activity
GII81_18560	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII81_18565	COG1874	Beta-galactosidase
GII81_18570	COG3833	ABC-type maltose transport systems, permease component
GII81_18575	COG1175	transmembrane transport
GII81_18580	COG2182	Extracellular solute-binding protein
GII81_18585	COG1609	Transcriptional regulator
GII81_18590	COG2186	Transcriptional regulator
GII81_18595	COG1620	l-lactate permease
GII81_18600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII81_18610	COG5039	Polysaccharide pyruvyl transferase
GII81_18615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII81_18620	COG0110	maltose O-acetyltransferase activity
GII81_18625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII81_18630	COG2244	polysaccharide biosynthetic process
GII81_18635	COG1216	Glycosyl transferase, family 2
GII81_18640	COG5039	Polysaccharide pyruvyl transferase
GII81_18645	COG1216	Glycosyl transferase, family 2
GII81_18655	COG0438	transferase activity, transferring glycosyl groups
GII81_18660	COG1215	transferase activity, transferring glycosyl groups
GII81_18665	COG0438	transferase activity, transferring glycosyl groups
GII81_18670	COG1086	Polysaccharide biosynthesis protein
GII81_18675	COG0489	protein tyrosine kinase activity
GII81_18680	COG3944	biosynthesis protein
GII81_18685	COG1396	sequence-specific DNA binding
GII81_18690	COG2272	Belongs to the type-B carboxylesterase lipase family
GII81_18700	COG3479	Phenolic acid decarboxylase
GII81_18710	COG1794	racemase activity, acting on amino acids and derivatives
GII81_18715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII81_18720	COG1621	beta-fructofuranosidase activity
GII81_18725	COG1621	beta-fructofuranosidase activity
GII81_18730	COG0531	amino acid
GII81_18735	COG1309	transcriptional regulator
GII81_18740	COG2076	Multidrug Resistance protein
GII81_18745	COG2076	Multidrug Resistance protein
GII81_18755	COG0277	FAD linked oxidase domain protein
GII81_18760	COG3621	Patatin-like phospholipase
GII81_18770	COG0740	serine-type endopeptidase activity
GII81_18775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII81_18780	COG0366	Alpha amylase catalytic
GII81_18785	COG1554	hydrolase, family 65, central catalytic
GII81_18790	COG5521	maltodextrose utilization protein MalA
GII81_18795	COG3833	ABC-type maltose transport systems, permease component
GII81_18800	COG1175	transmembrane transport
GII81_18805	COG2182	Extracellular solute-binding protein
GII81_18810	COG0366	Alpha amylase catalytic
GII81_18815	COG1609	Transcriptional regulator
GII81_18820	COG1611	Belongs to the LOG family
GII81_18825	COG1694	Mazg nucleotide pyrophosphohydrolase
GII81_18830	COG0659	secondary active sulfate transmembrane transporter activity
GII81_18835	COG0288	reversible hydration of carbon dioxide
GII81_18840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII81_18845	COG0577	efflux transmembrane transporter activity
GII81_18850	COG1136	(ABC) transporter
GII81_18855	COG5002	protein histidine kinase activity
GII81_18860	COG0745	RESPONSE REGULATOR receiver
GII81_18870	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII81_18875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_18880	COG1481	regulation of sporulation
GII81_18885	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII81_18890	COG1660	Displays ATPase and GTPase activities
GII81_18895	COG1051	belongs to the nudix hydrolase family
GII81_18900	COG0492	ferredoxin-NADP+ reductase activity
GII81_18905	COG3883	PFAM NLP P60 protein
GII81_18905	COG0791	NLP P60 protein
GII81_18910	COG0457	Tetratricopeptide repeat
GII81_18915	COG1132	(ABC) transporter
GII81_18935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII81_18935	COG0140	phosphoribosyl-ATP diphosphatase activity
GII81_18940	COG0107	imidazoleglycerol-phosphate synthase activity
GII81_18945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII81_18950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII81_18955	COG0131	Imidazoleglycerol-phosphate dehydratase
GII81_18960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII81_18965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII81_18970	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII81_18975	COG4990	cell redox homeostasis
GII81_18980	COG5297	Belongs to the glycosyl hydrolase family 6
GII81_18985	COG0110	maltose O-acetyltransferase activity
GII81_18990	COG0546	phosphoglycolate phosphatase activity
GII81_18995	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII81_19000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII81_19005	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII81_19010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII81_19015	COG0363	glucosamine-6-phosphate deaminase activity
GII81_19025	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII81_19030	COG1846	Transcriptional regulator
GII81_19035	COG2124	cytochrome p450
GII81_19045	COG1846	Transcriptional regulator
GII81_19050	COG2814	Major facilitator Superfamily
GII81_19055	COG1950	PFAM Membrane protein of
GII81_19060	COG1983	PspC domain protein
GII81_19065	COG3595	metallopeptidase activity
GII81_19080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII81_19085	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII81_19090	COG0556	nucleotide-excision repair
GII81_19095	COG4897	Protein conserved in bacteria
GII81_19100	COG0574	Belongs to the PEP-utilizing enzyme family
GII81_19100	COG3848	Pyruvate phosphate dikinase
GII81_19105	COG1309	transcriptional regulator
GII81_19110	COG2814	Major facilitator Superfamily
GII81_19115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII81_19125	COG0793	Belongs to the peptidase S41A family
GII81_19125	COG3409	Peptidoglycan-binding domain 1 protein
GII81_19130	COG2177	Part of the ABC transporter FtsEX involved in
GII81_19135	COG2884	Cell division ATP-binding protein ftsE
GII81_19140	COG2010	Cytochrome c
GII81_19145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_19155	COG0653	protein targeting
GII81_19160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII81_19175	COG1516	flagellar protein fliS
GII81_19180	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII81_19185	COG1334	flagellar protein FlaG
GII81_19190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII81_19195	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII81_19200	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII81_19210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII81_19215	COG1256	bacterial-type flagellum assembly
GII81_19215	COG4786	Flagellar basal body rod
GII81_19220	COG3418	PFAM FlgN family protein
GII81_19225	COG2747	anti-sigma28 factor FlgM
GII81_19235	COG1040	competence protein
GII81_19245	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII81_19250	COG1307	EDD domain protein, DegV family
GII81_19255	COG2197	response regulator
GII81_19260	COG4585	Histidine kinase
GII81_19265	COG1739	Uncharacterized protein family UPF0029
GII81_19270	COG1316	TRANSCRIPTIONal
GII81_19275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII81_19280	COG0438	transferase activity, transferring glycosyl groups
GII81_19285	COG1215	transferase activity, transferring glycosyl groups
GII81_19290	COG3206	protein involved in exopolysaccharide biosynthesis
GII81_19295	COG3307	-O-antigen
GII81_19300	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII81_19305	COG0297	glycogen (starch) synthase activity
GII81_19305	COG0438	transferase activity, transferring glycosyl groups
GII81_19310	COG2244	polysaccharide biosynthetic process
GII81_19325	COG2247	cell wall binding repeat
GII81_19325	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_19330	COG2247	cell wall binding repeat
GII81_19330	COG2385	sporulation resulting in formation of a cellular spore
GII81_19340	COG1316	TRANSCRIPTIONal
GII81_19345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII81_19365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII81_19370	COG1134	teichoic acid transport
GII81_19375	COG1682	transport, permease protein
GII81_19390	COG1215	transferase activity, transferring glycosyl groups
GII81_19390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII81_19395	COG0463	Glycosyl transferase, family 2
GII81_19440	COG4193	domain, Protein
GII81_19445	COG1482	cell wall glycoprotein biosynthetic process
GII81_19450	COG0697	spore germination
GII81_19455	COG0814	amino acid
GII81_19465	COG2814	Major facilitator Superfamily
GII81_19470	COG1316	TRANSCRIPTIONal
GII81_19475	COG0561	phosphatase activity
GII81_19480	COG0791	NLP P60 protein
GII81_19490	COG2843	Capsule synthesis protein
GII81_19500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII81_19505	COG1609	Transcriptional regulator
GII81_19510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII81_19515	COG1869	D-ribose catabolic process
GII81_19520	COG1129	ABC transporter
GII81_19525	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII81_19530	COG1879	ABC-type sugar transport system periplasmic component
GII81_19535	COG3103	Sh3 type 3 domain protein
GII81_19545	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII81_19550	COG3527	Alpha-acetolactate decarboxylase
GII81_19555	COG0028	Belongs to the TPP enzyme family
GII81_19560	COG0583	DNA-binding transcription factor activity
GII81_19565	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII81_19580	COG5337	Spore coat protein CotH
GII81_19590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII81_19600	COG0405	Gamma-glutamyltransferase
GII81_19605	COG1522	sequence-specific DNA binding
GII81_19610	COG2059	Chromate
GII81_19615	COG2059	Chromate
GII81_19625	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII81_19630	COG0583	DNA-binding transcription factor activity
GII81_19660	COG5444	nuclease activity
GII81_19680	COG3878	Protein conserved in bacteria
GII81_19685	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII81_19690	COG4464	protein tyrosine phosphatase activity
GII81_19695	COG0489	protein tyrosine kinase activity
GII81_19700	COG3944	biosynthesis protein
GII81_19710	COG4715	Zinc finger, swim domain protein
GII81_19715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII81_19720	COG0561	phosphatase activity
GII81_19725	COG1349	DNA-binding transcription factor activity
GII81_19730	COG0629	single-stranded DNA binding
GII81_19745	COG3764	Sortase (surface protein transpeptidase)
GII81_19750	COG0745	RESPONSE REGULATOR receiver
GII81_19750	COG2972	Histidine kinase
GII81_19755	COG1970	mechanosensitive ion channel activity
GII81_19760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII81_19765	COG0457	Tetratricopeptide repeat
GII81_19770	COG4786	Flagellar basal body rod
GII81_19775	COG4786	Flagellar basal body rod
GII81_19780	COG1077	Cell shape determining protein MreB Mrl
GII81_19785	COG1609	Transcriptional regulator
GII81_19795	COG1846	Transcriptional regulator
GII81_19800	COG2814	Major facilitator Superfamily
GII81_19805	COG3420	alginic acid biosynthetic process
GII81_19810	COG1953	Uracil, thiamine, allantoin
GII81_19815	COG0477	Major facilitator Superfamily
GII81_19820	COG1335	isochorismatase
GII81_19830	COG0004	ammonium transporteR
GII81_19835	COG0347	Belongs to the P(II) protein family
GII81_19840	COG0671	phosphoesterase, PA-phosphatase related
GII81_19850	COG0739	heme binding
GII81_19855	COG1247	-acetyltransferase
GII81_19875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII81_19880	COG0789	Transcriptional regulator
GII81_19890	COG2910	NAD(P)H-binding
GII81_19895	COG1959	2 iron, 2 sulfur cluster binding
GII81_19900	COG0804	urea catabolic process
GII81_19905	COG0832	Belongs to the urease beta subunit family
GII81_19910	COG0831	urea catabolic process
GII81_19925	COG3237	CsbD-like
GII81_19930	COG1994	Peptidase M50
GII81_19935	COG0457	Tetratricopeptide repeat
GII81_19940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII81_19945	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII81_19955	COG2304	oxidoreductase activity
GII81_19965	COG2304	oxidoreductase activity
GII81_19970	COG2385	sporulation resulting in formation of a cellular spore
GII81_19975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII81_19985	COG4836	Membrane
GII81_19995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII81_20000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII81_20005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII81_20010	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII81_20015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII81_20020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII81_20025	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII81_20030	COG0356	it plays a direct role in the translocation of protons across the membrane
GII81_20040	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII81_20045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII81_20050	COG4475	Protein of unknown function (DUF436)
GII81_20055	COG0698	ribose 5-phosphate isomerase
GII81_20060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII81_20065	COG1971	Probably functions as a manganese efflux pump
GII81_20070	COG0009	L-threonylcarbamoyladenylate synthase
GII81_20075	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII81_20095	COG2890	protein-(glutamine-N5) methyltransferase activity
GII81_20100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII81_20105	COG0346	lactoylglutathione lyase activity
GII81_20110	COG0789	Transcriptional regulator
GII81_20115	COG0679	Auxin Efflux Carrier
GII81_20120	COG0281	malic enzyme
GII81_20125	COG1435	thymidine kinase activity
GII81_20130	COG0254	rRNA binding
GII81_20135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII81_20145	COG1494	fructose-1,6-bisphosphatase
GII81_20150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII81_20155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII81_20160	COG0191	fructose-bisphosphate aldolase activity
GII81_20165	COG2204	response regulator
GII81_20170	COG4821	SIS domain
GII81_20175	COG0504	CTP synthase activity
GII81_20180	COG3343	RNA polymerase activity
GII81_20185	COG1960	acyl-CoA dehydrogenase activity
GII81_20190	COG0247	lactate metabolic process
GII81_20190	COG2181	nitrate reductase activity
GII81_20195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII81_20200	COG4294	response to UV
GII81_20210	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII81_20215	COG1132	(ABC) transporter
GII81_20220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII81_20225	COG2181	nitrate reductase activity
GII81_20230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GII81_20235	COG1140	nitrate reductase beta subunit
GII81_20240	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII81_20245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII81_20255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII81_20260	COG2223	nitrite transmembrane transporter activity
GII81_20265	COG0018	arginyl-trna synthetase
GII81_20270	COG4506	Protein conserved in bacteria
GII81_20285	COG0535	radical SAM domain protein
GII81_20295	COG1131	(ABC) transporter
GII81_20300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII81_20305	COG0612	Peptidase, M16
GII81_20310	COG0612	Peptidase, M16
GII81_20320	COG3391	amine dehydrogenase activity
GII81_20325	COG3391	amine dehydrogenase activity
GII81_20335	COG0457	Tetratricopeptide repeat
GII81_20365	COG1131	(ABC) transporter
GII81_20375	COG0010	Belongs to the arginase family
GII81_20380	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII81_20385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII81_20395	COG1994	Peptidase M50
GII81_20400	COG1942	4-Oxalocrotonate Tautomerase
GII81_20405	COG1846	Transcriptional regulator
GII81_20410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII81_20415	COG0477	Major facilitator Superfamily
GII81_20420	COG1959	2 iron, 2 sulfur cluster binding
GII81_20425	COG3465	dGTPase activity
GII81_20430	COG1078	dGTPase activity
GII81_20435	COG4844	belongs to the
GII81_20445	COG0697	spore germination
GII81_20450	COG0095	Lipoate-protein ligase
GII81_20455	COG0583	DNA-binding transcription factor activity
GII81_20460	COG0280	phosphate acetyltransferase
GII81_20470	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_20475	COG0436	Aminotransferase
GII81_20480	COG2814	Major facilitator Superfamily
GII81_20485	COG0151	Belongs to the GarS family
GII81_20490	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_20495	COG1917	Cupin 2, conserved barrel domain protein
GII81_20500	COG0077	Prephenate dehydratase
GII81_20505	COG2814	Major facilitator Superfamily
GII81_20510	COG0833	amino acid
GII81_20515	COG4187	Peptidase family M20/M25/M40
GII81_20520	COG1012	belongs to the aldehyde dehydrogenase family
GII81_20525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII81_20535	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII81_20540	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII81_20545	COG1088	dTDP-glucose 4,6-dehydratase activity
GII81_20550	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII81_20555	COG3980	spore coat polysaccharide biosynthesis protein
GII81_20560	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII81_20565	COG2089	acid synthase
GII81_20570	COG0456	acetyltransferase
GII81_20575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII81_20580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII81_20585	COG0463	Glycosyl transferase, family 2
GII81_20595	COG2363	Small membrane protein
GII81_20600	COG2233	PERMEase
GII81_20615	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII81_20620	COG1216	Glycosyl transferase, family 2
GII81_20625	COG0351	phosphomethylpyrimidine kinase
GII81_20635	COG1621	beta-fructofuranosidase activity
GII81_20640	COG1263	PTS System
GII81_20640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_20645	COG2116	formate transmembrane transporter activity
GII81_20650	COG3711	transcriptional antiterminator
GII81_20660	COG1404	Belongs to the peptidase S8 family
GII81_20665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_20670	COG0778	Nitroreductase
GII81_20675	COG0772	Belongs to the SEDS family
GII81_20685	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII81_20690	COG1845	cytochrome c oxidase, subunit III
GII81_20695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII81_20700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII81_20705	COG2261	transglycosylase associated protein
GII81_20710	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII81_20715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII81_20720	COG2246	polysaccharide biosynthetic process
GII81_20725	COG1309	transcriptional regulator
GII81_20735	COG3162	membrane
GII81_20740	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII81_20745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII81_20750	COG2837	iron assimilation
GII81_20755	COG2822	iron ion transport
GII81_20760	COG0672	)-iron permease
GII81_20765	COG0352	thiamine-phosphate diphosphorylase activity
GII81_20770	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII81_20775	COG0583	DNA-binding transcription factor activity
GII81_20780	COG1380	Effector of murein hydrolase LrgA
GII81_20785	COG1346	cytolysis
GII81_20790	COG2814	Major facilitator Superfamily
GII81_20795	COG4895	conserved protein (DUF2196)
GII81_20800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII81_20805	COG0346	lactoylglutathione lyase activity
GII81_20810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII81_20815	COG1404	Belongs to the peptidase S8 family
GII81_20820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_20820	COG1263	PTS System
GII81_20825	COG3711	transcriptional antiterminator
GII81_20830	COG1442	glycosyl transferase family 8
GII81_20835	COG5522	Integral membrane protein (intg_mem_TP0381)
GII81_20840	COG1846	Transcriptional regulator
GII81_20845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII81_20850	COG2234	aminopeptidase activity
GII81_20870	COG2357	RelA SpoT domain protein
GII81_20875	COG1575	Belongs to the MenA family. Type 1 subfamily
GII81_20890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_20895	COG1696	Membrane protein involved in D-alanine export
GII81_20900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_20905	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII81_20910	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII81_20915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII81_20920	COG1486	melibiose metabolic process
GII81_20925	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII81_20930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII81_20935	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII81_20940	COG3711	transcriptional antiterminator
GII81_20940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_20950	COG2094	Belongs to the DNA glycosylase MPG family
GII81_20955	COG0753	catalase activity
GII81_20965	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII81_20970	COG1131	(ABC) transporter
GII81_20990	COG1595	DNA-templated transcription, initiation
GII81_20995	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII81_21000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII81_21005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII81_21010	COG4988	ABC transporter
GII81_21015	COG1294	oxidase, subunit
GII81_21020	COG1271	oxidase subunit
GII81_21025	COG3493	citrate carrier protein
GII81_21030	COG0501	Belongs to the peptidase M48B family
GII81_21040	COG0726	polysaccharide deacetylase
GII81_21045	COG3842	ATPase activity
GII81_21050	COG2508	Transcriptional regulator
GII81_21055	COG1012	belongs to the aldehyde dehydrogenase family
GII81_21060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_21070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII81_21075	COG1881	PFAM PEBP family protein
GII81_21080	COG0583	DNA-binding transcription factor activity
GII81_21090	COG4585	Histidine kinase
GII81_21095	COG2197	response regulator
GII81_21100	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII81_21110	COG4894	glucomannan catabolic process
GII81_21115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII81_21120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII81_21125	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_21130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII81_21135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII81_21140	COG2610	gluconate transmembrane transporter activity
GII81_21145	COG0500	methyltransferase
GII81_21150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII81_21165	COG0753	catalase activity
GII81_21165	COG0693	protein deglycase activity
GII81_21170	COG2851	Citrate transporter
GII81_21175	COG2273	Hydrolase Family 16
GII81_21180	COG3711	transcriptional antiterminator
GII81_21190	COG2270	Major facilitator Superfamily
GII81_21195	COG0513	Belongs to the DEAD box helicase family
GII81_21200	COG3401	FG-GAP repeat protein
GII81_21200	COG2755	lipolytic protein G-D-S-L family
GII81_21230	COG0697	spore germination
GII81_21235	COG0589	response to stress
GII81_21240	COG2723	6-phospho-beta-galactosidase activity
GII81_21245	COG1263	PTS System
GII81_21245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_21245	COG2190	(PTS) system
GII81_21260	COG5444	nuclease activity
GII81_21275	COG3507	Belongs to the glycosyl hydrolase 43 family
GII81_21290	COG2986	histidine ammonia-lyase
GII81_21295	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII81_21300	COG1228	amidohydrolase
GII81_21305	COG0010	Belongs to the arginase family
GII81_21310	COG0833	amino acid
GII81_21315	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII81_21320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII81_21325	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII81_21330	COG2390	Transcriptional regulator
GII81_21340	COG3192	ethanolamine utilization protein
GII81_21345	COG2079	MmgE PrpD family protein
GII81_21355	COG1126	abc transporter atp-binding protein
GII81_21360	COG0765	amino acid transport
GII81_21365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_21385	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII81_21390	COG0561	phosphatase activity
GII81_21420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_21425	COG5294	Protein conserved in bacteria
GII81_21430	COG0577	efflux transmembrane transporter activity
GII81_21435	COG1136	(ABC) transporter
GII81_21440	COG2205	protein histidine kinase activity
GII81_21445	COG0745	RESPONSE REGULATOR receiver
GII81_21450	COG0191	fructose-bisphosphate aldolase activity
GII81_21455	COG1082	Xylose isomerase domain protein TIM barrel
GII81_21460	COG1082	Xylose isomerase domain protein TIM barrel
GII81_21465	COG0673	inositol 2-dehydrogenase activity
GII81_21470	COG2814	Major facilitator Superfamily
GII81_21475	COG1082	Xylose isomerase domain protein TIM barrel
GII81_21480	COG3962	Belongs to the TPP enzyme family
GII81_21485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII81_21495	COG1012	belongs to the aldehyde dehydrogenase family
GII81_21500	COG1349	DNA-binding transcription factor activity
GII81_21505	COG0667	Aldo Keto reductase
GII81_21520	COG2814	Major facilitator Superfamily
GII81_21525	COG0326	Molecular chaperone. Has ATPase activity
GII81_21535	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_21540	COG1309	transcriptional regulator
GII81_21545	COG1012	belongs to the aldehyde dehydrogenase family
GII81_21550	COG1714	RDD family
GII81_21555	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GII81_21565	COG1714	RDD family
GII81_21570	COG2311	Membrane
GII81_21575	COG1917	Cupin 2, conserved barrel domain protein
GII81_21580	COG1309	transcriptional regulator
GII81_21585	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_21590	COG1846	Transcriptional regulator
GII81_21595	COG1380	Effector of murein hydrolase LrgA
GII81_21600	COG1346	cytolysis
GII81_21605	COG5039	Polysaccharide pyruvyl transferase
GII81_21610	COG1929	Belongs to the glycerate kinase type-1 family
GII81_21615	COG1802	Transcriptional regulator
GII81_21620	COG1070	Carbohydrate kinase
GII81_21625	COG2610	gluconate transmembrane transporter activity
GII81_21630	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII81_21635	COG0450	alkyl hydroperoxide reductase
GII81_21640	COG3634	alkyl hydroperoxide reductase activity
GII81_21650	COG2723	6-phospho-beta-galactosidase activity
GII81_21655	COG2190	(PTS) system
GII81_21660	COG2190	(PTS) system
GII81_21660	COG1263	PTS System
GII81_21660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_21665	COG2188	Transcriptional regulator
GII81_21675	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII81_21710	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII81_21725	COG1063	alcohol dehydrogenase
GII81_21745	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII81_21750	COG0456	acetyltransferase
GII81_21755	COG0457	Tetratricopeptide repeat
GII81_21765	COG0010	Belongs to the arginase family
GII81_21770	COG0833	amino acid
GII81_21775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII81_21780	COG3829	transcription factor binding
GII81_21785	COG5002	protein histidine kinase activity
GII81_21810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII81_21815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII81_21820	COG4853	Protein conserved in bacteria
GII81_21825	COG4863	YycH protein
GII81_21830	COG5002	protein histidine kinase activity
GII81_21835	COG0745	RESPONSE REGULATOR receiver
GII81_21865	COG0346	lactoylglutathione lyase activity
GII81_21870	COG0305	Participates in initiation and elongation during chromosome replication
GII81_21885	COG3093	addiction module antidote protein HigA
GII81_21890	COG2807	transmembrane transport
GII81_21895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII81_21900	COG0359	binds to the 23S rRNA
GII81_21905	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII81_21910	COG4241	membrane
GII81_21920	COG5577	PFAM Coat F domain
GII81_21925	COG1733	regulation of RNA biosynthetic process
GII81_21930	COG1227	inorganic diphosphatase activity
GII81_21945	COG2271	Major facilitator Superfamily
GII81_21950	COG0789	Transcriptional regulator
GII81_21950	COG4978	Transcriptional regulator
GII81_21960	COG4319	ketosteroid isomerase
GII81_21965	COG1357	PFAM Pentapeptide repeats (8 copies)
GII81_21970	COG2814	Major facilitator Superfamily
GII81_21975	COG0583	DNA-binding transcription factor activity
GII81_21980	COG2153	protein acetylation
GII81_21990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_21995	COG1846	Transcriptional regulator
GII81_22000	COG2153	protein acetylation
GII81_22005	COG2364	Membrane
GII81_22010	COG0456	acetyltransferase
GII81_22015	COG2315	Protein conserved in bacteria
GII81_22020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII81_22030	COG2814	Major facilitator Superfamily
GII81_22040	COG1331	Highly conserved protein containing a thioredoxin domain
GII81_22055	COG0789	Transcriptional regulator
GII81_22060	COG0697	spore germination
GII81_22070	COG1280	lysine exporter protein (LysE YggA)
GII81_22075	COG1331	Highly conserved protein containing a thioredoxin domain
GII81_22085	COG1266	CAAX protease self-immunity
GII81_22090	COG0477	Major facilitator Superfamily
GII81_22090	COG2814	Major facilitator Superfamily
GII81_22095	COG0110	maltose O-acetyltransferase activity
GII81_22100	COG0346	lactoylglutathione lyase activity
GII81_22105	COG1609	Transcriptional regulator
GII81_22110	COG0708	Exodeoxyribonuclease III
GII81_22115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII81_22120	COG0629	single-stranded DNA binding
GII81_22125	COG0360	Binds together with S18 to 16S ribosomal RNA
GII81_22130	COG0012	GTP binding
GII81_22135	COG0243	molybdopterin cofactor binding
GII81_22140	COG4481	Protein conserved in bacteria
GII81_22145	COG3949	Membrane
GII81_22155	COG1475	DNA binding
GII81_22160	COG1192	Involved in chromosome partitioning
GII81_22170	COG1475	DNA binding
GII81_22175	COG0357	Ribosomal RNA small subunit methyltransferase G
GII81_22180	COG0445	tRNA wobble uridine modification
GII81_22185	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII81_22190	COG1847	R3H domain protein
GII81_22195	COG0706	membrane insertase activity
GII81_22200	COG0594	ribonuclease P activity
GII81_22205	COG0230	Belongs to the bacterial ribosomal protein bL34 family