locus-tag	class	description
GII82_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII82_00010	COG0592	DNA-directed DNA polymerase activity
GII82_00015	COG2501	S4 domain
GII82_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII82_00030	COG0187	DNA topoisomerase II activity
GII82_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII82_00070	COG0517	IMP dehydrogenase activity
GII82_00070	COG0516	GMP reductase activity
GII82_00075	COG1686	Belongs to the peptidase S11 family
GII82_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII82_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII82_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII82_00100	COG1428	Deoxynucleoside kinase
GII82_00105	COG1428	Deoxynucleoside kinase
GII82_00110	COG3858	chitin binding
GII82_00110	COG1388	LysM domain
GII82_00115	COG1335	isochorismatase
GII82_00120	COG0590	tRNA wobble adenosine to inosine editing
GII82_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII82_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII82_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII82_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII82_00190	COG3853	Toxic anion resistance protein (TelA)
GII82_00195	COG1982	Orn Lys Arg decarboxylase major
GII82_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII82_00205	COG3870	Protein conserved in bacteria
GII82_00210	COG1728	Protein conserved in bacteria
GII82_00215	COG0470	DNA polymerase III
GII82_00220	COG1774	PSP1 C-terminal conserved region
GII82_00225	COG4467	Involved in initiation control of chromosome replication
GII82_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII82_00235	COG2827	Endonuclease containing a URI domain
GII82_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII82_00245	COG2002	toxin-antitoxin pair type II binding
GII82_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII82_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII82_00255	COG0084	hydrolase, TatD family'
GII82_00260	COG3584	3D domain protein
GII82_00260	COG3583	domain protein
GII82_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII82_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII82_00280	COG4466	Protein conserved in bacteria
GII82_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII82_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII82_00300	COG0251	oxidation-reduction process
GII82_00305	COG2088	sporulation resulting in formation of a cellular spore
GII82_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII82_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII82_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII82_00325	COG0193	aminoacyl-tRNA hydrolase activity
GII82_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII82_00340	COG2002	toxin-antitoxin pair type II binding
GII82_00345	COG2244	polysaccharide biosynthetic process
GII82_00350	COG3956	TIGRFAM MazG family protein
GII82_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII82_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII82_00375	COG1098	S1 RNA binding domain
GII82_00390	COG2208	phosphoserine phosphatase activity
GII82_00395	COG2304	oxidoreductase activity
GII82_00400	COG0515	serine threonine protein kinase
GII82_00405	COG0037	tRNA processing
GII82_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII82_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII82_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII82_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII82_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII82_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII82_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII82_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII82_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII82_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII82_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII82_00470	COG1396	sequence-specific DNA binding
GII82_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII82_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII82_00560	COG4463	regulation of RNA biosynthetic process
GII82_00565	COG3880	PFAM UvrB UvrC protein
GII82_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII82_00575	COG0542	response to heat
GII82_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII82_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII82_00590	COG4956	integral membrane protein (PIN domain superfamily)
GII82_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII82_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII82_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII82_00610	COG1045	serine acetyltransferase
GII82_00615	COG0215	cysteine-tRNA ligase activity
GII82_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII82_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII82_00630	COG3688	RNA-binding protein containing a PIN domain
GII82_00635	COG1595	DNA-templated transcription, initiation
GII82_00640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII82_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII82_00650	COG0250	Participates in transcription elongation, termination and antitermination
GII82_00655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GII82_00660	COG0081	regulation of translation
GII82_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII82_00670	COG0222	ribosome binding
GII82_00675	COG2813	Specifically methylates the guanine in position
GII82_00680	COG0085	RNA polymerase activity
GII82_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII82_00690	COG1358	cellular component organization or biogenesis
GII82_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII82_00700	COG0049	tRNA binding
GII82_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII82_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII82_00715	COG0596	Alpha beta hydrolase
GII82_00720	COG0051	transcription antitermination factor activity, RNA binding
GII82_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII82_00730	COG0088	Forms part of the polypeptide exit tunnel
GII82_00735	COG0089	rRNA binding
GII82_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII82_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GII82_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GII82_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GII82_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII82_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
GII82_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII82_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII82_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII82_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII82_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII82_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII82_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII82_00815	COG1841	ribosomal large subunit assembly
GII82_00820	COG0200	Binds to the 23S rRNA
GII82_00825	COG0201	protein transport
GII82_00830	COG0563	adenylate kinase activity
GII82_00835	COG0024	Methionine aminopeptidase
GII82_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII82_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GII82_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII82_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII82_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII82_00865	COG0202	RNA polymerase activity
GII82_00870	COG0203	ribosomal protein L17
GII82_00875	COG1122	ATPase activity
GII82_00880	COG1122	ATPase activity
GII82_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII82_00890	COG0101	tRNA pseudouridine synthase activity
GII82_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII82_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII82_00905	COG2226	methyltransferase
GII82_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII82_00920	COG0489	protein tyrosine kinase activity
GII82_00930	COG2194	sulfuric ester hydrolase activity
GII82_00935	COG0726	polysaccharide deacetylase
GII82_01015	COG0659	secondary active sulfate transmembrane transporter activity
GII82_01020	COG0385	Bile acid
GII82_01025	COG2819	hydrolase of the alpha beta superfamily
GII82_01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII82_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII82_01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII82_01045	COG2207	Transcriptional regulator
GII82_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII82_01050	COG3876	Protein conserved in bacteria
GII82_01055	COG1472	Belongs to the glycosyl hydrolase 3 family
GII82_01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII82_01065	COG1263	PTS System
GII82_01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII82_01070	COG1737	Transcriptional regulator
GII82_01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII82_01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII82_01085	COG1683	Conserved Protein
GII82_01115	COG1595	DNA-templated transcription, initiation
GII82_01120	COG5662	AntiSigma factor
GII82_01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII82_01130	COG4856	YbbR-like protein
GII82_01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII82_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII82_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII82_01160	COG2169	Transcriptional regulator
GII82_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII82_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII82_01175	COG3002	Belongs to the UPF0753 family
GII82_01180	COG0288	reversible hydration of carbon dioxide
GII82_01190	COG5609	conserved protein (DUF2294)
GII82_01195	COG0640	Transcriptional regulator
GII82_01200	COG2814	Major facilitator Superfamily
GII82_01215	COG1404	Belongs to the peptidase S8 family
GII82_01235	COG1132	(ABC) transporter
GII82_01240	COG0596	Alpha beta hydrolase
GII82_01245	COG0745	RESPONSE REGULATOR receiver
GII82_01250	COG0642	Histidine kinase
GII82_01260	COG0515	serine threonine protein kinase
GII82_01275	COG1113	amino acid transport
GII82_01290	COG2602	Beta-lactamase
GII82_01295	COG2124	cytochrome p450
GII82_01305	COG0531	amino acid
GII82_01310	COG0584	glycerophosphoryl diester phosphodiesterase
GII82_01315	COG2271	Major facilitator Superfamily
GII82_01325	COG0456	acetyltransferase
GII82_01325	COG1846	Transcriptional regulator
GII82_01330	COG2271	Major facilitator Superfamily
GII82_01340	COG3409	Peptidoglycan-binding domain 1 protein
GII82_01345	COG0697	spore germination
GII82_01350	COG1917	Cupin 2, conserved barrel domain protein
GII82_01350	COG2207	Transcriptional regulator
GII82_01355	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII82_01360	COG3591	Belongs to the peptidase S1B family
GII82_01370	COG0596	Alpha beta hydrolase
GII82_01375	COG1183	phosphatidylcholine synthase activity
GII82_01380	COG0586	Pfam SNARE associated Golgi protein
GII82_01385	COG0688	phosphatidylethanolamine metabolic process
GII82_01400	COG1301	dicarboxylic acid transport
GII82_01405	COG1263	PTS System
GII82_01405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII82_01405	COG2190	(PTS) system
GII82_01410	COG0363	glucosamine-6-phosphate deaminase activity
GII82_01425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII82_01430	COG0833	amino acid
GII82_01435	COG2040	homocysteine
GII82_01445	COG1115	amino acid carrier protein
GII82_01450	COG2066	Belongs to the glutaminase family
GII82_01455	COG4191	Histidine kinase
GII82_01460	COG0784	Response regulator, receiver
GII82_01465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII82_01470	COG1012	belongs to the aldehyde dehydrogenase family
GII82_01475	COG2271	Major facilitator Superfamily
GII82_01480	COG4948	Mandelate Racemase Muconate Lactonizing
GII82_01485	COG2186	Transcriptional regulator
GII82_01490	COG2721	sulfolactate sulfo-lyase activity
GII82_01495	COG3173	Aminoglycoside phosphotransferase
GII82_01510	COG0745	RESPONSE REGULATOR receiver
GII82_01515	COG2205	protein histidine kinase activity
GII82_01520	COG1131	(ABC) transporter
GII82_01540	COG3773	Cell wall hydrolase
GII82_01545	COG2304	oxidoreductase activity
GII82_01555	COG3540	Alkaline phosphatase
GII82_01560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII82_01565	COG0805	protein transport
GII82_01570	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII82_01575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII82_01580	COG0477	Major facilitator Superfamily
GII82_01585	COG1309	transcriptional regulator
GII82_01590	COG0252	asparaginase activity
GII82_01595	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII82_01600	COG1714	RDD family
GII82_01605	COG1405	negative regulation of cell septum assembly
GII82_01605	COG3012	SEC-C Motif Domain Protein
GII82_01610	COG3290	protein histidine kinase activity
GII82_01615	COG3279	Response regulator of the LytR AlgR family
GII82_01620	COG4555	ABC transporter
GII82_01625	COG1668	transmembrane transport
GII82_01630	COG0667	Aldo Keto reductase
GII82_01645	COG1595	DNA-templated transcription, initiation
GII82_01650	COG1595	DNA-templated transcription, initiation
GII82_01655	COG1876	peptidase activity
GII82_01660	COG0457	Tetratricopeptide repeat
GII82_01665	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_01670	COG0366	Alpha amylase catalytic
GII82_01675	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII82_01680	COG1121	(ABC) transporter
GII82_01685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII82_01690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII82_01695	COG2310	stress, protein
GII82_01700	COG2310	stress, protein
GII82_01705	COG2310	stress, protein
GII82_01710	COG0861	Integral membrane protein TerC family
GII82_01720	COG3853	Toxic anion resistance protein (TelA)
GII82_01725	COG0477	Major facilitator Superfamily
GII82_01730	COG2814	Major facilitator Superfamily
GII82_01735	COG0640	Transcriptional regulator
GII82_01740	COG0517	IMP dehydrogenase activity
GII82_01740	COG4175	Glycine betaine
GII82_01745	COG4176	ABC-type proline glycine betaine transport system permease component
GII82_01750	COG2113	Glycine betaine
GII82_01755	COG1473	amidohydrolase
GII82_01760	COG1288	antiporter activity
GII82_01770	COG0366	Alpha amylase catalytic
GII82_01775	COG0039	L-malate dehydrogenase activity
GII82_01780	COG1620	l-lactate permease
GII82_01785	COG2814	Major facilitator Superfamily
GII82_01790	COG1846	Transcriptional regulator
GII82_01795	COG1280	lysine exporter protein (LysE YggA)
GII82_01800	COG3403	YqcI/YcgG family
GII82_01805	COG1113	amino acid transport
GII82_01810	COG3665	Urea carboxylase-associated protein
GII82_01815	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII82_01820	COG1660	Displays ATPase and GTPase activities
GII82_01825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII82_01830	COG2226	methyltransferase
GII82_01835	COG0583	DNA-binding transcription factor activity
GII82_01840	COG3458	cephalosporin-C deacetylase activity
GII82_01845	COG3541	Predicted nucleotidyltransferase
GII82_01850	COG0506	proline dehydrogenase activity
GII82_01855	COG1012	belongs to the aldehyde dehydrogenase family
GII82_01860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII82_01865	COG2508	Transcriptional regulator
GII82_01870	COG3689	TIGRFAM TIGR03943 family protein
GII82_01875	COG0701	Predicted permease
GII82_01880	COG2267	carboxylic ester hydrolase activity
GII82_01885	COG0492	ferredoxin-NADP+ reductase activity
GII82_01890	COG1587	Uroporphyrinogen-III synthase
GII82_01890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII82_01895	COG2146	nitrite reductase [NAD(P)H] activity
GII82_01900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII82_01905	COG0243	molybdopterin cofactor binding
GII82_01910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII82_01915	COG2223	nitrite transmembrane transporter activity
GII82_01920	COG1469	GTP cyclohydrolase I activity
GII82_01925	COG1376	ErfK ybiS ycfS ynhG family protein
GII82_01935	COG0523	cobalamin synthesis protein
GII82_01940	COG0765	amino acid transport
GII82_01945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII82_01955	COG1714	RDD family
GII82_01965	COG2723	6-phospho-beta-galactosidase activity
GII82_01975	COG3209	COG3209 Rhs family protein
GII82_01980	COG0840	transmembrane signaling receptor activity
GII82_01980	COG3290	protein histidine kinase activity
GII82_01985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII82_01990	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII82_01995	COG1733	regulation of RNA biosynthetic process
GII82_02000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_02005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_02010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_02015	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII82_02020	COG2814	Major facilitator Superfamily
GII82_02030	COG0697	spore germination
GII82_02045	COG2364	Membrane
GII82_02050	COG1126	abc transporter atp-binding protein
GII82_02055	COG0765	amino acid transport
GII82_02060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII82_02065	COG0583	DNA-binding transcription factor activity
GII82_02070	COG0163	prenyltransferase activity
GII82_02075	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII82_02090	COG0596	Alpha beta hydrolase
GII82_02095	COG3104	oligopeptide transport
GII82_02100	COG5434	Belongs to the glycosyl hydrolase 28 family
GII82_02110	COG0697	spore germination
GII82_02120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII82_02125	COG1136	(ABC) transporter
GII82_02130	COG0577	efflux transmembrane transporter activity
GII82_02135	COG0745	RESPONSE REGULATOR receiver
GII82_02140	COG3850	Histidine kinase
GII82_02140	COG5002	protein histidine kinase activity
GII82_02145	COG0457	Tetratricopeptide repeat
GII82_02165	COG0527	aspartate kinase activity
GII82_02170	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII82_02175	COG4605	iron ion homeostasis
GII82_02180	COG4604	ABC transporter, ATP-binding protein
GII82_02185	COG4607	ABC-type enterochelin transport system periplasmic component
GII82_02190	COG2814	Major facilitator Superfamily
GII82_02195	COG1309	transcriptional regulator
GII82_02200	COG0778	Nitroreductase
GII82_02205	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII82_02210	COG0640	Transcriptional regulator
GII82_02215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII82_02220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII82_02225	COG1012	belongs to the aldehyde dehydrogenase family
GII82_02230	COG4975	Glucose uptake
GII82_02235	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_02240	COG4549	nuclear export factor GLE1
GII82_02245	COG1276	copper resistance
GII82_02245	COG2372	response to copper ion
GII82_02250	COG1349	DNA-binding transcription factor activity
GII82_02260	COG2213	PTS system mannitol-specific
GII82_02265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII82_02270	COG0246	Mannitol dehydrogenase
GII82_02275	COG0473	3-isopropylmalate dehydrogenase activity
GII82_02280	COG0681	Belongs to the peptidase S26 family
GII82_02285	COG0412	Dienelactone hydrolase
GII82_02290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII82_02300	COG0561	phosphatase activity
GII82_02305	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII82_02310	COG1914	H( )-stimulated, divalent metal cation uptake system
GII82_02315	COG4336	lyase activity
GII82_02320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII82_02325	COG1984	allophanate hydrolase subunit 2
GII82_02330	COG1414	Transcriptional regulator
GII82_02335	COG2755	lipolytic protein G-D-S-L family
GII82_02345	COG2329	Antibiotic biosynthesis monooxygenase
GII82_02350	COG0768	penicillin binding
GII82_02355	COG4989	oxidoreductase activity
GII82_02360	COG3711	transcriptional antiterminator
GII82_02365	COG0318	PFAM AMP-dependent synthetase and ligase
GII82_02370	COG2226	methyltransferase
GII82_02375	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_02380	COG1917	Cupin 2, conserved barrel domain protein
GII82_02385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII82_02390	COG3871	stress protein (general stress protein 26)
GII82_02400	COG2814	Major facilitator Superfamily
GII82_02405	COG1522	sequence-specific DNA binding
GII82_02410	COG0551	DNA topoisomerase type I activity
GII82_02410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII82_02415	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII82_02420	COG3706	GGDEF domain
GII82_02425	COG5298	Protein conserved in bacteria
GII82_02430	COG1215	transferase activity, transferring glycosyl groups
GII82_02440	COG0531	amino acid
GII82_02445	COG0494	nUDIX hydrolase
GII82_02450	COG0028	Belongs to the TPP enzyme family
GII82_02465	COG1914	H( )-stimulated, divalent metal cation uptake system
GII82_02470	COG2261	transglycosylase associated protein
GII82_02475	COG4876	unkown
GII82_02480	COG2217	Heavy metal translocating P-type atpase
GII82_02485	COG3729	General stress protein
GII82_02490	COG0662	Cupin 2, conserved barrel domain protein
GII82_02495	COG2329	Antibiotic biosynthesis monooxygenase
GII82_02500	COG3546	catalase activity
GII82_02505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII82_02510	COG3290	protein histidine kinase activity
GII82_02515	COG4565	transcriptional regulatory protein
GII82_02520	COG1301	dicarboxylic acid transport
GII82_02525	COG0628	permease
GII82_02530	COG1131	(ABC) transporter
GII82_02535	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII82_02545	COG1960	acyl-CoA dehydrogenase activity
GII82_02560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII82_02565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII82_02570	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII82_02575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII82_02580	COG0513	Belongs to the DEAD box helicase family
GII82_02585	COG3402	PFAM membrane-flanked domain
GII82_02590	COG3428	Bacterial PH domain
GII82_02595	COG0705	Rhomboid family
GII82_02600	COG0736	holo-[acyl-carrier-protein] synthase activity
GII82_02605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII82_02610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII82_02615	COG0864	Transcriptional regulator
GII82_02620	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII82_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
GII82_02630	COG1366	Belongs to the anti-sigma-factor antagonist family
GII82_02635	COG2172	sigma factor antagonist activity
GII82_02640	COG2208	phosphoserine phosphatase activity
GII82_02645	COG1366	Belongs to the anti-sigma-factor antagonist family
GII82_02650	COG2172	sigma factor antagonist activity
GII82_02655	COG1191	sigma factor activity
GII82_02660	COG2208	phosphoserine phosphatase activity
GII82_02665	COG2183	response to ionizing radiation
GII82_02675	COG3091	SprT-like family
GII82_02715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII82_02760	COG1476	TRANSCRIPTIONal
GII82_02780	COG0693	protein deglycase activity
GII82_02785	COG1278	Cold shock
GII82_02790	COG1329	Transcriptional regulator
GII82_02795	COG0697	spore germination
GII82_02800	COG1917	Cupin 2, conserved barrel domain protein
GII82_02800	COG2207	Transcriptional regulator
GII82_02805	COG0697	spore germination
GII82_02810	COG3708	Transcriptional regulator
GII82_02810	COG2207	Transcriptional regulator
GII82_02815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII82_02820	COG0477	Major facilitator Superfamily
GII82_02830	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII82_02865	COG1309	transcriptional regulator
GII82_02870	COG0697	spore germination
GII82_02875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII82_02880	COG2030	dehydratase
GII82_02885	COG3545	Serine hydrolase
GII82_02890	COG1733	regulation of RNA biosynthetic process
GII82_02895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII82_02900	COG2814	Major facilitator Superfamily
GII82_02905	COG1309	transcriptional regulator
GII82_02915	COG0640	Transcriptional regulator
GII82_02920	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII82_02930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII82_02935	COG0697	spore germination
GII82_02940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII82_02945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII82_02950	COG0640	Transcriptional regulator
GII82_02955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII82_02970	COG4585	Histidine kinase
GII82_02975	COG2197	response regulator
GII82_02980	COG2409	Drug exporters of the RND superfamily
GII82_02985	COG0596	Alpha beta hydrolase
GII82_02990	COG1811	Na channel or pump
GII82_02995	COG4978	Transcriptional regulator
GII82_02995	COG0789	Transcriptional regulator
GII82_03000	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII82_03005	COG0778	Nitroreductase
GII82_03010	COG0346	lactoylglutathione lyase activity
GII82_03015	COG2259	Doxx family
GII82_03020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII82_03035	COG2323	membrane
GII82_03040	COG2323	membrane
GII82_03045	COG0071	Belongs to the small heat shock protein (HSP20) family
GII82_03060	COG1309	transcriptional regulator
GII82_03070	COG0456	acetyltransferase
GII82_03080	COG0673	inositol 2-dehydrogenase activity
GII82_03085	COG1609	Transcriptional regulator
GII82_03090	COG2814	Major facilitator Superfamily
GII82_03105	COG1113	amino acid transport
GII82_03110	COG2318	DinB family
GII82_03115	COG1846	Transcriptional regulator
GII82_03120	COG1033	growth of symbiont in host cell
GII82_03120	COG2409	Drug exporters of the RND superfamily
GII82_03125	COG0778	Nitroreductase
GII82_03130	COG1846	Transcriptional regulator
GII82_03135	COG2814	Major facilitator Superfamily
GII82_03140	COG0730	response to heat
GII82_03145	COG1802	Transcriptional regulator
GII82_03150	COG1388	LysM domain
GII82_03150	COG3858	chitin binding
GII82_03155	COG1819	glycosyl
GII82_03165	COG1785	Belongs to the alkaline phosphatase family
GII82_03170	COG5646	InterPro IPR014922
GII82_03180	COG0454	-acetyltransferase
GII82_03185	COG1078	dGTPase activity
GII82_03190	COG1388	LysM domain
GII82_03195	COG2814	Major facilitator Superfamily
GII82_03200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII82_03205	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII82_03210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII82_03215	COG2723	6-phospho-beta-galactosidase activity
GII82_03220	COG2188	Transcriptional regulator
GII82_03225	COG1940	carbohydrate kinase activity
GII82_03230	COG1482	cell wall glycoprotein biosynthetic process
GII82_03235	COG4124	Belongs to the glycosyl hydrolase 26 family
GII82_03280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII82_03285	COG0802	atpase or kinase
GII82_03290	COG1214	PFAM Peptidase M22, glycoprotease
GII82_03295	COG0456	acetyltransferase
GII82_03300	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII82_03305	COG0488	(ABC) transporter
GII82_03310	COG0315	cyclic pyranopterin monophosphate synthase activity
GII82_03315	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII82_03320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII82_03325	COG0805	protein transport
GII82_03335	COG1266	CAAX protease self-immunity
GII82_03340	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GII82_03345	COG0459	protein refolding
GII82_03355	COG1073	alpha beta
GII82_03360	COG0457	Tetratricopeptide repeat
GII82_03365	COG1063	alcohol dehydrogenase
GII82_03370	COG2211	Major facilitator Superfamily
GII82_03375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII82_03380	COG1842	Phage shock protein A
GII82_03385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII82_03390	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII82_03395	COG4260	virion core protein, lumpy skin disease virus
GII82_03405	COG2814	Major facilitator Superfamily
GII82_03410	COG1063	alcohol dehydrogenase
GII82_03415	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII82_03420	COG0823	Involved in the tonB-independent uptake of proteins
GII82_03435	COG2267	carboxylic ester hydrolase activity
GII82_03445	COG2132	Multicopper oxidase
GII82_03450	COG1113	amino acid transport
GII82_03460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII82_03465	COG0714	Associated with various cellular activities
GII82_03470	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII82_03475	COG1305	Transglutaminase-like
GII82_03480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII82_03480	COG0519	Catalyzes the synthesis of GMP from XMP
GII82_03485	COG2252	PERMEase
GII82_03490	COG3064	Membrane
GII82_03500	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII82_03510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII82_03515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII82_03520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII82_03525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII82_03530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII82_03535	COG0047	phosphoribosylformylglycinamidine synthase activity
GII82_03540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII82_03545	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII82_03550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII82_03555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII82_03560	COG0138	bifunctional purine biosynthesis protein purh
GII82_03565	COG0151	Belongs to the GarS family
GII82_03570	COG1522	sequence-specific DNA binding
GII82_03575	COG0531	amino acid
GII82_03585	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII82_03590	COG1470	cell adhesion involved in biofilm formation
GII82_03595	COG4496	protein, YerC YecD
GII82_03600	COG0069	glutamate synthase activity
GII82_03605	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII82_03610	COG0210	DNA helicase
GII82_03615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII82_03620	COG4851	CamS sex pheromone cAM373 precursor
GII82_03625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII82_03630	COG1285	pathogenesis
GII82_03635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII82_03640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII82_03645	COG0154	amidase activity
GII82_03650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII82_03655	COG1309	transcriptional regulator
GII82_03660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII82_03665	COG1597	lipid kinase activity
GII82_03670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII82_03700	COG5444	nuclease activity
GII82_03710	COG3586	endonuclease activity
GII82_03720	COG0457	Tetratricopeptide repeat
GII82_03730	COG0217	transcriptional regulatory protein
GII82_03740	COG1309	transcriptional regulator
GII82_03745	COG3631	Ketosteroid isomerase-related protein
GII82_03750	COG0702	epimerase
GII82_03765	COG3546	catalase activity
GII82_03770	COG0454	-acetyltransferase
GII82_03780	COG5578	integral membrane protein
GII82_03785	COG2972	Histidine kinase
GII82_03790	COG4753	response regulator
GII82_03790	COG2207	Transcriptional regulator
GII82_03795	COG1653	transport
GII82_03800	COG1175	transmembrane transport
GII82_03805	COG0395	ABC-type sugar transport system, permease component
GII82_03810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII82_03815	COG2207	Transcriptional regulator
GII82_03820	COG2755	lipolytic protein G-D-S-L family
GII82_03830	COG5578	integral membrane protein
GII82_03835	COG3401	FG-GAP repeat protein
GII82_03840	COG3401	FG-GAP repeat protein
GII82_03845	COG2755	lipolytic protein G-D-S-L family
GII82_03850	COG1874	Beta-galactosidase
GII82_03860	COG1653	transport
GII82_03865	COG4209	transmembrane transport
GII82_03870	COG0395	ABC-type sugar transport system, permease component
GII82_03875	COG1486	melibiose metabolic process
GII82_03880	COG2323	membrane
GII82_03885	COG2329	Antibiotic biosynthesis monooxygenase
GII82_03890	COG0346	lactoylglutathione lyase activity
GII82_03905	COG5583	Uncharacterized small protein (DUF2292)
GII82_03910	COG0670	Belongs to the BI1 family
GII82_03915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII82_03920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII82_03925	COG0134	indole-3-glycerol-phosphate synthase activity
GII82_03930	COG0133	tryptophan synthase activity
GII82_03935	COG0159	tryptophan synthase activity
GII82_03940	COG0135	phosphoribosylanthranilate isomerase activity
GII82_03965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII82_03975	COG0673	inositol 2-dehydrogenase activity
GII82_03995	COG0697	spore germination
GII82_04000	COG1846	Transcriptional regulator
GII82_04005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII82_04035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII82_04035	COG2124	cytochrome p450
GII82_04040	COG1368	sulfuric ester hydrolase activity
GII82_04045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII82_04050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII82_04055	COG1442	glycosyl transferase family 8
GII82_04060	COG1216	Glycosyl transferase, family 2
GII82_04065	COG1442	glycosyl transferase family 8
GII82_04070	COG2223	nitrite transmembrane transporter activity
GII82_04075	COG1011	Hydrolase
GII82_04080	COG0531	amino acid
GII82_04085	COG1012	belongs to the aldehyde dehydrogenase family
GII82_04090	COG0840	transmembrane signaling receptor activity
GII82_04095	COG0488	(ABC) transporter
GII82_04105	COG0789	Transcriptional regulator
GII82_04110	COG2814	Major facilitator Superfamily
GII82_04120	COG0488	(ABC) transporter
GII82_04125	COG0513	Belongs to the DEAD box helicase family
GII82_04130	COG0456	acetyltransferase
GII82_04135	COG2130	NADP-dependent
GII82_04140	COG2211	Major facilitator Superfamily
GII82_04145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GII82_04150	COG1120	ATPase activity
GII82_04155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII82_04160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII82_04165	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII82_04180	COG3866	Pectate lyase
GII82_04185	COG0471	metal ion transport
GII82_04190	COG3290	protein histidine kinase activity
GII82_04195	COG4565	transcriptional regulatory protein
GII82_04200	COG3181	Tripartite tricarboxylate transporter family receptor
GII82_04205	COG2851	Citrate transporter
GII82_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII82_04215	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII82_04220	COG1254	Belongs to the acylphosphatase family
GII82_04225	COG2258	MOSC domain
GII82_04245	COG0024	Methionine aminopeptidase
GII82_04250	COG1263	PTS System
GII82_04250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII82_04255	COG1368	sulfuric ester hydrolase activity
GII82_04270	COG1115	amino acid carrier protein
GII82_04275	COG0531	amino acid
GII82_04290	COG0697	spore germination
GII82_04295	COG1263	PTS System
GII82_04295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII82_04300	COG0366	Alpha amylase catalytic
GII82_04305	COG2188	Transcriptional regulator
GII82_04310	COG0778	Nitroreductase
GII82_04315	COG0737	Belongs to the 5'-nucleotidase family
GII82_04320	COG0693	protein deglycase activity
GII82_04325	COG2814	Major facilitator Superfamily
GII82_04330	COG4840	Belongs to the UPF0435 family
GII82_04335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII82_04340	COG4980	gas vesicle protein
GII82_04345	COG1295	ribonuclease BN
GII82_04350	COG0477	Major facilitator Superfamily
GII82_04355	COG0387	Pfam Sodium calcium exchanger
GII82_04365	COG0668	transmembrane transport
GII82_04370	COG0535	radical SAM domain protein
GII82_04380	COG0726	polysaccharide deacetylase
GII82_04385	COG2084	Dehydrogenase
GII82_04390	COG0598	Magnesium transport protein CorA
GII82_04395	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII82_04400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII82_04410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII82_04415	COG4637	Psort location Cytoplasmic, score
GII82_04420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII82_04425	COG0022	dehydrogenase e1 component
GII82_04430	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII82_04435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII82_04440	COG3284	Transcriptional regulator
GII82_04450	COG1742	UPF0060 membrane protein
GII82_04475	COG4842	Belongs to the WXG100 family
GII82_04480	COG1486	melibiose metabolic process
GII82_04485	COG1737	Transcriptional regulator
GII82_04490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII82_04490	COG1263	PTS System
GII82_04495	COG1132	(ABC) transporter
GII82_04500	COG1132	(ABC) transporter
GII82_04505	COG2259	Doxx family
GII82_04510	COG2514	catechol 2,3-dioxygenase activity
GII82_04515	COG4585	Histidine kinase
GII82_04520	COG2197	response regulator
GII82_04525	COG1131	(ABC) transporter
GII82_04530	COG0842	Transport permease protein
GII82_04530	COG1511	domain protein
GII82_04535	COG0842	Transport permease protein
GII82_04540	COG1695	Transcriptional regulator
GII82_04550	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII82_04555	COG2318	DinB family
GII82_04560	COG2814	Major facilitator Superfamily
GII82_04565	COG1846	Transcriptional regulator
GII82_04570	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII82_04570	COG0392	lysyltransferase activity
GII82_04575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII82_04580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII82_04585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII82_04590	COG0384	phenazine biosynthesis protein PhzF
GII82_04595	COG0778	Nitroreductase
GII82_04610	COG1090	epimerase
GII82_04615	COG2137	regulation of response to DNA damage stimulus
GII82_04625	COG2814	Major facilitator Superfamily
GII82_04640	COG3103	Sh3 type 3 domain protein
GII82_04645	COG5658	integral membrane protein
GII82_04650	COG0596	Alpha beta hydrolase
GII82_04655	COG0463	Glycosyl transferase, family 2
GII82_04660	COG4485	Bacterial membrane protein, YfhO
GII82_04665	COG1988	membrane-bound metal-dependent
GII82_04670	COG1194	a g-specific adenine glycosylase
GII82_04680	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_04695	COG3557	Belongs to the UPF0374 family
GII82_04700	COG1132	(ABC) transporter
GII82_04705	COG4129	membrane
GII82_04710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII82_04715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII82_04720	COG0735	belongs to the Fur family
GII82_04830	COG4326	sporulation control protein
GII82_04840	COG5577	PFAM Coat F domain
GII82_04845	COG3340	Belongs to the peptidase S51 family
GII82_04850	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII82_04855	COG0277	FAD linked oxidase domain protein
GII82_04865	COG0753	catalase activity
GII82_04870	COG1116	anion transmembrane transporter activity
GII82_04875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII82_04880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII82_04885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII82_04895	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII82_04905	COG1476	TRANSCRIPTIONal
GII82_04915	COG3382	B3 4 domain protein
GII82_04920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII82_04930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII82_04935	COG0789	Transcriptional regulator
GII82_04940	COG1664	Polymer-forming cytoskeletal
GII82_04945	COG1664	Polymer-forming cytoskeletal
GII82_04950	COG2766	serine protein kinase
GII82_04955	COG2718	Belongs to the UPF0229 family
GII82_04960	COG1846	Transcriptional regulator
GII82_04965	COG1566	PFAM secretion protein HlyD family protein
GII82_04970	COG2814	Major facilitator Superfamily
GII82_04975	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII82_04995	COG1725	Transcriptional regulator
GII82_05000	COG1131	(ABC) transporter
GII82_05005	COG1131	(ABC) transporter
GII82_05010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII82_05015	COG1278	Cold shock
GII82_05020	COG1464	Belongs to the NlpA lipoprotein family
GII82_05025	COG3706	GGDEF domain
GII82_05030	COG1823	symporter activity
GII82_05050	COG5577	PFAM Coat F domain
GII82_05055	COG4085	toxin activity
GII82_05055	COG1525	nuclease
GII82_05055	COG0737	Belongs to the 5'-nucleotidase family
GII82_05060	COG3764	Sortase (surface protein transpeptidase)
GII82_05065	COG0564	pseudouridine synthase activity
GII82_05075	COG0517	IMP dehydrogenase activity
GII82_05080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII82_05085	COG3153	acetyltransferase
GII82_05085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII82_05090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII82_05095	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII82_05100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII82_05105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII82_05110	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII82_05115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII82_05120	COG4585	Histidine kinase
GII82_05120	COG2203	Gaf domain
GII82_05125	COG2197	response regulator
GII82_05130	COG0431	NADPH-dependent FMN reductase
GII82_05145	COG0791	NLP P60 protein
GII82_05145	COG1388	LysM domain
GII82_05150	COG1959	2 iron, 2 sulfur cluster binding
GII82_05155	COG0668	transmembrane transport
GII82_05160	COG2719	SpoVR family
GII82_05165	COG1785	Belongs to the alkaline phosphatase family
GII82_05170	COG0791	NLP P60 protein
GII82_05170	COG1388	LysM domain
GII82_05175	COG0583	DNA-binding transcription factor activity
GII82_05180	COG0372	Belongs to the citrate synthase family
GII82_05185	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_05190	COG0531	amino acid
GII82_05195	COG0733	neurotransmitter:sodium symporter activity
GII82_05200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII82_05205	COG0456	acetyltransferase
GII82_05220	COG1595	DNA-templated transcription, initiation
GII82_05225	COG0667	Aldo Keto reductase
GII82_05230	COG0204	Acyl-transferase
GII82_05235	COG1253	flavin adenine dinucleotide binding
GII82_05240	COG0789	Transcriptional regulator
GII82_05245	COG0436	Aminotransferase
GII82_05250	COG1253	flavin adenine dinucleotide binding
GII82_05255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII82_05260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII82_05265	COG0584	glycerophosphoryl diester phosphodiesterase
GII82_05275	COG0668	transmembrane transport
GII82_05280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII82_05285	COG0726	polysaccharide deacetylase
GII82_05290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII82_05295	COG1757	Na H antiporter
GII82_05300	COG0589	response to stress
GII82_05310	COG1132	(ABC) transporter
GII82_05315	COG1132	(ABC) transporter
GII82_05320	COG0702	epimerase
GII82_05340	COG0189	ligase activity
GII82_05345	COG0189	ligase activity
GII82_05350	COG4399	Belongs to the UPF0754 family
GII82_05355	COG3679	Belongs to the UPF0342 family
GII82_05360	COG4335	DNA alkylation repair
GII82_05365	COG0561	phosphatase activity
GII82_05370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII82_05375	COG0475	glutathione-regulated potassium exporter activity
GII82_05380	COG0490	domain, Protein
GII82_05390	COG1024	Enoyl-CoA hydratase
GII82_05400	COG4152	abc transporter atp-binding protein
GII82_05405	COG1668	transmembrane transport
GII82_05410	COG0420	3'-5' exonuclease activity
GII82_05415	COG4717	serine-type aminopeptidase activity
GII82_05420	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII82_05430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII82_05460	COG1846	Transcriptional regulator
GII82_05465	COG4980	gas vesicle protein
GII82_05480	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII82_05485	COG0537	adenosine 5'-monophosphoramidase activity
GII82_05490	COG1131	(ABC) transporter
GII82_05495	COG4473	ABC transporter
GII82_05505	COG1473	amidohydrolase
GII82_05510	COG3069	C4-dicarboxylate transmembrane transporter activity
GII82_05520	COG2329	Antibiotic biosynthesis monooxygenase
GII82_05525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII82_05530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII82_05545	COG1309	transcriptional regulator
GII82_05550	COG1511	domain protein
GII82_05555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII82_05560	COG4377	Putative membrane peptidase family (DUF2324)
GII82_05570	COG1363	Peptidase, m42
GII82_05575	COG4405	Protein conserved in bacteria
GII82_05580	COG1301	dicarboxylic acid transport
GII82_05590	COG1234	tRNA 3'-trailer cleavage
GII82_05595	COG0095	Lipoate-protein ligase
GII82_05600	COG0702	epimerase
GII82_05605	COG0318	PFAM AMP-dependent synthetase and ligase
GII82_05615	COG0501	Belongs to the peptidase M48B family
GII82_05620	COG1404	Belongs to the peptidase S8 family
GII82_05625	COG0456	acetyltransferase
GII82_05630	COG0604	alcohol dehydrogenase
GII82_05635	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII82_05640	COG0406	alpha-ribazole phosphatase activity
GII82_05645	COG0183	Belongs to the thiolase family
GII82_05650	COG0318	PFAM AMP-dependent synthetase and ligase
GII82_05655	COG1268	BioY protein
GII82_05660	COG0840	transmembrane signaling receptor activity
GII82_05665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII82_05665	COG0723	plastoquinol--plastocyanin reductase activity
GII82_05670	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_05680	COG4903	ComK protein
GII82_05685	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_05695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII82_05710	COG0398	Pfam SNARE associated Golgi protein
GII82_05715	COG0681	Belongs to the peptidase S26 family
GII82_05720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII82_05725	COG1846	Transcriptional regulator
GII82_05730	COG0738	Major facilitator superfamily
GII82_05735	COG0673	inositol 2-dehydrogenase activity
GII82_05740	COG0561	phosphatase activity
GII82_05745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII82_05750	COG1609	Transcriptional regulator
GII82_05755	COG3180	Ammonia monooxygenase
GII82_05760	COG0477	Major facilitator Superfamily
GII82_05760	COG2814	Major facilitator Superfamily
GII82_05765	COG4533	DNA binding
GII82_05775	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII82_05780	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII82_05785	COG1074	ATP-dependent DNA helicase activity
GII82_05790	COG0420	3'-5' exonuclease activity
GII82_05795	COG0419	ATPase involved in DNA repair
GII82_05800	COG1403	HNH endonuclease
GII82_05840	COG5337	Spore coat protein CotH
GII82_05845	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII82_05855	COG1404	Belongs to the peptidase S8 family
GII82_05865	COG0367	asparagine synthase
GII82_05870	COG2318	DinB family
GII82_05875	COG1562	ergosterol biosynthetic process
GII82_05880	COG0534	Mate efflux family protein
GII82_05885	COG2207	Transcriptional regulator
GII82_05885	COG1917	Cupin 2, conserved barrel domain protein
GII82_05890	COG1609	Transcriptional regulator
GII82_05895	COG0673	inositol 2-dehydrogenase activity
GII82_05900	COG2318	DinB family
GII82_05905	COG1279	arginine transmembrane transporter activity
GII82_05910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII82_05915	COG1357	PFAM Pentapeptide repeats (8 copies)
GII82_05920	COG2267	carboxylic ester hydrolase activity
GII82_05925	COG0529	Catalyzes the synthesis of activated sulfate
GII82_05930	COG2046	Belongs to the sulfate adenylyltransferase family
GII82_05935	COG0175	sulfate reduction
GII82_05940	COG2045	Belongs to the ComB family
GII82_05945	COG1809	phosphosulfolactate synthase activity
GII82_05950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII82_05955	COG4948	Mandelate Racemase Muconate Lactonizing
GII82_05960	COG2814	Major facilitator Superfamily
GII82_05965	COG0454	-acetyltransferase
GII82_05970	COG2153	protein acetylation
GII82_05975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII82_05975	COG0646	methionine synthase
GII82_05980	COG1666	GTP binding
GII82_05985	COG2996	Protein conserved in bacteria
GII82_06005	COG1695	Transcriptional regulator
GII82_06020	COG3227	Zinc metalloprotease (Elastase)
GII82_06025	COG1307	EDD domain protein, DegV family
GII82_06030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII82_06045	COG0561	phosphatase activity
GII82_06050	COG1073	alpha beta
GII82_06055	COG2151	metal-sulfur cluster biosynthetic enzyme
GII82_06065	COG0277	FAD linked oxidase domain protein
GII82_06070	COG2271	Major facilitator Superfamily
GII82_06075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII82_06090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII82_06095	COG0505	Belongs to the CarA family
GII82_06100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII82_06105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII82_06120	COG2267	carboxylic ester hydrolase activity
GII82_06130	COG1744	ABC transporter substrate-binding protein PnrA-like
GII82_06145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII82_06150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII82_06155	COG5504	Zn-dependent protease
GII82_06160	COG0444	Belongs to the ABC transporter superfamily
GII82_06165	COG4608	Belongs to the ABC transporter superfamily
GII82_06175	COG0601	transmembrane transport
GII82_06180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII82_06190	COG0180	Tryptophanyl-tRNA synthetase
GII82_06195	COG4166	transmembrane transport
GII82_06200	COG0601	transmembrane transport
GII82_06205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII82_06210	COG0444	Belongs to the ABC transporter superfamily
GII82_06215	COG4608	Belongs to the ABC transporter superfamily
GII82_06220	COG2814	Major facilitator Superfamily
GII82_06225	COG0456	acetyltransferase
GII82_06230	COG1393	Belongs to the ArsC family
GII82_06235	COG0861	Integral membrane protein TerC family
GII82_06245	COG4862	establishment of competence for transformation
GII82_06255	COG4469	Competence protein
GII82_06260	COG1164	Oligoendopeptidase f
GII82_06275	COG2346	COG2346, Truncated hemoglobins
GII82_06280	COG0741	lytic transglycosylase activity
GII82_06285	COG4116	CYTH
GII82_06295	COG2357	RelA SpoT domain protein
GII82_06300	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII82_06305	COG0564	pseudouridine synthase activity
GII82_06310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII82_06315	COG0569	domain protein
GII82_06315	COG0475	glutathione-regulated potassium exporter activity
GII82_06320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII82_06325	COG0352	thiamine-phosphate diphosphorylase activity
GII82_06330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII82_06335	COG2104	thiamine diphosphate biosynthetic process
GII82_06340	COG2022	thiamine diphosphate biosynthetic process
GII82_06345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII82_06350	COG0351	phosphomethylpyrimidine kinase
GII82_06355	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII82_06410	COG0210	DNA helicase
GII82_06420	COG2153	protein acetylation
GII82_06425	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII82_06430	COG2382	esterase
GII82_06435	COG0626	cystathionine gamma-synthase activity
GII82_06440	COG0626	cystathionine gamma-synthase activity
GII82_06445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII82_06450	COG5505	Protein of unknown function (DUF819)
GII82_06465	COG5444	nuclease activity
GII82_06500	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII82_06505	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_06515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII82_06515	COG3711	transcriptional antiterminator
GII82_06520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII82_06520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII82_06520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII82_06525	COG1482	cell wall glycoprotein biosynthetic process
GII82_06535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII82_06545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII82_06560	COG0109	protoheme IX farnesyltransferase activity
GII82_06570	COG0726	polysaccharide deacetylase
GII82_06585	COG5504	Zn-dependent protease
GII82_06590	COG2205	protein histidine kinase activity
GII82_06600	COG3383	formate dehydrogenase (NAD+) activity
GII82_06605	COG2427	Protein of unknown function (DUF1641)
GII82_06615	COG1051	belongs to the nudix hydrolase family
GII82_06625	COG2124	cytochrome p450
GII82_06630	COG1819	glycosyl
GII82_06640	COG1587	Uroporphyrinogen-III synthase
GII82_06645	COG0390	transport system, permease component
GII82_06650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII82_06655	COG0697	spore germination
GII82_06660	COG4297	protein containing double-stranded beta helix domain
GII82_06670	COG1252	NADH dehydrogenase
GII82_06675	COG1904	glucuronate isomerase
GII82_06680	COG2211	Major facilitator Superfamily
GII82_06685	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII82_06690	COG1063	alcohol dehydrogenase
GII82_06695	COG1312	Catalyzes the dehydration of D-mannonate
GII82_06700	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_06705	COG2271	Major facilitator Superfamily
GII82_06710	COG1609	Transcriptional regulator
GII82_06715	COG0246	Mannitol dehydrogenase
GII82_06720	COG2721	sulfolactate sulfo-lyase activity
GII82_06725	COG0730	response to heat
GII82_06730	COG2318	DinB family
GII82_06735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII82_06740	COG0457	Tetratricopeptide repeat
GII82_06750	COG2350	Protein conserved in bacteria
GII82_06755	COG3409	Peptidoglycan-binding domain 1 protein
GII82_06755	COG1388	LysM domain
GII82_06755	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII82_06765	COG4195	phage-related replication protein
GII82_06770	COG3546	catalase activity
GII82_06775	COG2856	Zn peptidase
GII82_06780	COG1396	sequence-specific DNA binding
GII82_06790	COG1522	sequence-specific DNA binding
GII82_06795	COG1484	DNA-dependent DNA replication
GII82_06815	COG1595	DNA-templated transcription, initiation
GII82_06820	COG3728	DNA packaging
GII82_06820	COG5484	DNA packaging
GII82_06825	COG1783	phage Terminase large subunit
GII82_06830	COG5518	Phage portal protein
GII82_06835	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII82_06840	COG4653	Phage capsid family
GII82_06890	COG3953	SLT domain
GII82_06890	COG5412	phage tail tape measure protein
GII82_06890	COG5412	phage tail tape measure protein
GII82_06890	COG3953	SLT domain
GII82_06895	COG1652	LysM domain
GII82_06900	COG4193	domain, Protein
GII82_06910	COG3628	GPW Gp25 family protein
GII82_06915	COG3299	homolog of phage Mu protein gp47
GII82_06920	COG3778	Protein conserved in bacteria
GII82_06960	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII82_06960	COG3409	Peptidoglycan-binding domain 1 protein
GII82_06980	COG0306	phosphate transporter
GII82_06985	COG1392	Phosphate transport regulator
GII82_06990	COG0531	amino acid
GII82_06995	COG0346	lactoylglutathione lyase activity
GII82_07000	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII82_07005	COG0463	Glycosyl transferase, family 2
GII82_07010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII82_07015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII82_07020	COG2362	D-Aminopeptidase
GII82_07025	COG0601	transmembrane transport
GII82_07030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII82_07035	COG0444	Belongs to the ABC transporter superfamily
GII82_07040	COG4166	transmembrane transport
GII82_07045	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII82_07050	COG4948	Mandelate Racemase Muconate Lactonizing
GII82_07055	COG0791	NLP P60 protein
GII82_07060	COG4608	Belongs to the ABC transporter superfamily
GII82_07065	COG2706	6-phosphogluconolactonase activity
GII82_07070	COG1834	amidinotransferase
GII82_07075	COG1607	acyl-coa hydrolase
GII82_07080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII82_07080	COG1017	nitric oxide dioxygenase activity
GII82_07090	COG2323	membrane
GII82_07095	COG2318	DinB family
GII82_07100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII82_07105	COG2076	Multidrug Resistance protein
GII82_07110	COG2076	Multidrug Resistance protein
GII82_07115	COG0788	formyltetrahydrofolate deformylase activity
GII82_07120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII82_07125	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII82_07130	COG1764	response to oxidative stress
GII82_07135	COG1846	Transcriptional regulator
GII82_07140	COG1764	response to oxidative stress
GII82_07145	COG0590	tRNA wobble adenosine to inosine editing
GII82_07150	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII82_07155	COG1404	Belongs to the peptidase S8 family
GII82_07160	COG1366	Belongs to the anti-sigma-factor antagonist family
GII82_07165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII82_07170	COG1122	ATPase activity
GII82_07175	COG4721	ABC-type cobalt transport system, permease component
GII82_07185	COG0745	RESPONSE REGULATOR receiver
GII82_07190	COG5002	protein histidine kinase activity
GII82_07190	COG3850	Histidine kinase
GII82_07195	COG3212	peptidase
GII82_07200	COG3212	peptidase
GII82_07210	COG2239	Acts as a magnesium transporter
GII82_07215	COG0789	Transcriptional regulator
GII82_07230	COG1846	Transcriptional regulator
GII82_07235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII82_07240	COG0726	polysaccharide deacetylase
GII82_07245	COG1408	metallophosphoesterase
GII82_07255	COG0463	Glycosyl transferase, family 2
GII82_07260	COG3285	dna ligase
GII82_07260	COG1793	dna ligase
GII82_07265	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII82_07270	COG5001	Diguanylate cyclase
GII82_07270	COG3300	MHYT domain
GII82_07275	COG0586	Pfam SNARE associated Golgi protein
GII82_07280	COG0861	Integral membrane protein TerC family
GII82_07285	COG1191	sigma factor activity
GII82_07305	COG0501	Belongs to the peptidase M48B family
GII82_07310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII82_07325	COG3594	Acyltransferase
GII82_07330	COG5002	protein histidine kinase activity
GII82_07335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII82_07345	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII82_07350	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII82_07355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII82_07360	COG0436	Aminotransferase
GII82_07365	COG1850	ribulose-bisphosphate carboxylase activity
GII82_07370	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII82_07375	COG0235	Class ii aldolase
GII82_07380	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII82_07385	COG3339	Conserved Protein
GII82_07400	COG3852	Histidine kinase
GII82_07405	COG1846	Transcriptional regulator
GII82_07410	COG1360	Flagellar Motor Protein
GII82_07415	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII82_07420	COG0542	response to heat
GII82_07425	COG3949	Membrane
GII82_07430	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII82_07435	COG0720	synthase
GII82_07440	COG0602	queuosine metabolic process
GII82_07445	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII82_07450	COG1733	regulation of RNA biosynthetic process
GII82_07455	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_07460	COG1388	LysM domain
GII82_07460	COG4641	Protein conserved in bacteria
GII82_07465	COG1388	LysM domain
GII82_07470	COG3858	chitin binding
GII82_07480	COG4873	Protein conserved in bacteria
GII82_07490	COG3773	Cell wall hydrolase
GII82_07495	COG2244	polysaccharide biosynthetic process
GII82_07500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII82_07505	COG2217	Heavy metal translocating P-type atpase
GII82_07515	COG0006	proline dipeptidase activity
GII82_07520	COG1609	Transcriptional regulator
GII82_07525	COG3711	transcriptional antiterminator
GII82_07530	COG2190	(PTS) system
GII82_07530	COG1263	PTS System
GII82_07530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII82_07535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII82_07540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII82_07550	COG1533	DNA photolyase activity
GII82_07555	COG0456	acetyltransferase
GII82_07560	COG0840	transmembrane signaling receptor activity
GII82_07565	COG2084	Dehydrogenase
GII82_07570	COG2340	Cysteine-rich secretory protein family
GII82_07575	COG0768	penicillin binding
GII82_07580	COG4191	Histidine kinase
GII82_07585	COG0436	Aminotransferase
GII82_07595	COG0784	Response regulator, receiver
GII82_07595	COG0835	chemotaxis
GII82_07605	COG2814	Major facilitator Superfamily
GII82_07610	COG1376	ErfK ybiS ycfS ynhG family protein
GII82_07615	COG1408	metallophosphoesterase
GII82_07620	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_07625	COG2200	EAL domain
GII82_07630	COG4703	Protein of unknown function (DUF1797)
GII82_07635	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII82_07645	COG0517	IMP dehydrogenase activity
GII82_07650	COG0583	DNA-binding transcription factor activity
GII82_07655	COG0716	FMN binding
GII82_07665	COG0716	FMN binding
GII82_07670	COG2171	N-acyltransferase activity
GII82_07675	COG1473	amidohydrolase
GII82_07685	COG0668	transmembrane transport
GII82_07690	COG0450	alkyl hydroperoxide reductase
GII82_07695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII82_07710	COG0746	molybdenum cofactor guanylyltransferase activity
GII82_07715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII82_07720	COG0303	'Molybdopterin
GII82_07725	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII82_07730	COG0314	molybdopterin synthase activity
GII82_07735	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII82_07740	COG1132	(ABC) transporter
GII82_07745	COG1132	(ABC) transporter
GII82_07755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII82_07760	COG1136	(ABC) transporter
GII82_07765	COG0577	efflux transmembrane transporter activity
GII82_07770	COG1349	DNA-binding transcription factor activity
GII82_07775	COG1105	Belongs to the carbohydrate kinase PfkB family
GII82_07780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII82_07780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII82_07780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII82_07785	COG0681	Belongs to the peptidase S26 family
GII82_07795	COG0488	(ABC) transporter
GII82_07800	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII82_07805	COG2309	aminopeptidase activity
GII82_07815	COG1077	Cell shape determining protein MreB Mrl
GII82_07820	COG2002	toxin-antitoxin pair type II binding
GII82_07825	COG3852	Histidine kinase
GII82_07830	COG2105	PFAM AIG2 family protein
GII82_07830	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII82_07835	COG0569	domain protein
GII82_07840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII82_07845	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII82_07855	COG0561	phosphatase activity
GII82_07860	COG0242	peptide deformylase activity
GII82_07870	COG0497	DNA recombination
GII82_07875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII82_07880	COG0022	dehydrogenase e1 component
GII82_07885	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII82_07890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII82_07895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII82_07905	COG1982	Orn Lys Arg decarboxylase major
GII82_07910	COG4476	Belongs to the UPF0223 family
GII82_07915	COG4493	Belongs to the UPF0637 family
GII82_07925	COG0483	inositol monophosphate 1-phosphatase activity
GII82_07935	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII82_07955	COG1595	DNA-templated transcription, initiation
GII82_07985	COG4896	Protein conserved in bacteria
GII82_07995	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII82_08000	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII82_08005	COG2066	Belongs to the glutaminase family
GII82_08010	COG4838	Belongs to the UPF0358 family
GII82_08015	COG0772	Belongs to the SEDS family
GII82_08020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII82_08025	COG1612	heme a metabolic process
GII82_08030	COG0109	protoheme IX farnesyltransferase activity
GII82_08035	COG2010	Cytochrome c
GII82_08035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII82_08040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII82_08045	COG1845	cytochrome c oxidase, subunit III
GII82_08050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII82_08055	COG3336	cytochrome c oxidase
GII82_08065	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII82_08070	COG2340	Cysteine-rich secretory protein family
GII82_08085	COG3679	Belongs to the UPF0342 family
GII82_08090	COG4471	UPF0298 protein
GII82_08095	COG0742	ribosomal rna small subunit methyltransferase
GII82_08100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII82_08105	COG3314	Sporulation integral membrane protein YlbJ
GII82_08110	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII82_08115	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII82_08120	COG1323	Belongs to the UPF0348 family
GII82_08130	COG1399	metal-binding, possibly nucleic acid-binding protein
GII82_08135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GII82_08145	COG0454	-acetyltransferase
GII82_08150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII82_08155	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII82_08160	COG2001	Belongs to the MraZ family
GII82_08165	COG0275	rRNA processing
GII82_08170	COG4839	cell division protein FtsL
GII82_08180	COG0768	penicillin binding
GII82_08185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII82_08190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII82_08195	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII82_08200	COG0772	Belongs to the SEDS family
GII82_08205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII82_08210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII82_08215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII82_08220	COG3879	Bacterial protein of unknown function (DUF881)
GII82_08225	COG3879	Bacterial protein of unknown function (DUF881)
GII82_08230	COG3856	small basic protein
GII82_08235	COG0849	cell division
GII82_08240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII82_08245	COG4412	M6 family metalloprotease domain protein
GII82_08245	COG1404	Belongs to the peptidase S8 family
GII82_08255	COG1191	sigma factor activity
GII82_08260	COG1191	sigma factor activity
GII82_08265	COG1119	ATPase activity
GII82_08270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII82_08275	COG1873	PFAM PRC-barrel domain
GII82_08285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII82_08290	COG1799	cell septum assembly
GII82_08295	COG0762	integral membrane protein
GII82_08300	COG2302	S4 RNA-binding domain
GII82_08305	COG3599	regulation of cell shape
GII82_08310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII82_08315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII82_08320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII82_08325	COG0564	pseudouridine synthase activity
GII82_08330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII82_08335	COG2233	PERMEase
GII82_08340	COG0540	Belongs to the ATCase OTCase family
GII82_08345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII82_08350	COG0505	Belongs to the CarA family
GII82_08355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII82_08360	COG0543	2 iron, 2 sulfur cluster binding
GII82_08365	COG0167	dihydroorotate dehydrogenase activity
GII82_08370	COG0284	orotidine-5'-phosphate decarboxylase activity
GII82_08375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII82_08380	COG0175	sulfate reduction
GII82_08385	COG0306	phosphate transporter
GII82_08390	COG2046	Belongs to the sulfate adenylyltransferase family
GII82_08395	COG0529	Catalyzes the synthesis of activated sulfate
GII82_08400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII82_08405	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII82_08410	COG1648	precorrin-2 dehydrogenase activity
GII82_08420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII82_08425	COG1561	YicC-like family, N-terminal region
GII82_08430	COG2052	Domain of unknown function (DUF370)
GII82_08435	COG0194	GDP metabolic process
GII82_08440	COG1758	RNA polymerase activity
GII82_08445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII82_08450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII82_08455	COG0242	peptide deformylase activity
GII82_08460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII82_08465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII82_08465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII82_08470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII82_08475	COG0631	protein serine/threonine phosphatase activity
GII82_08480	COG2815	serine threonine protein kinase
GII82_08480	COG0515	serine threonine protein kinase
GII82_08485	COG1162	GTPase activity
GII82_08490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII82_08495	COG1564	THIamine pyrophosphokinase
GII82_08505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII82_08510	COG1302	Protein conserved in bacteria
GII82_08515	COG1461	Dihydroxyacetone kinase
GII82_08520	COG1760	l-serine dehydratase
GII82_08525	COG1760	l-serine dehydratase
GII82_08530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII82_08535	COG1349	DNA-binding transcription factor activity
GII82_08535	COG2050	protein possibly involved in aromatic compounds catabolism
GII82_08540	COG0416	fatty acid biosynthetic process
GII82_08545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII82_08550	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII82_08560	COG0571	ribonuclease III activity
GII82_08565	COG1196	nuclear chromosome segregation
GII82_08570	COG0552	protein localization to endoplasmic reticulum
GII82_08580	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII82_08585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII82_08590	COG0228	four-way junction DNA binding
GII82_08595	COG1837	Belongs to the UPF0109 family
GII82_08605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII82_08610	COG0336	Belongs to the RNA methyltransferase TrmD family
GII82_08615	COG0335	large ribosomal subunit rRNA binding
GII82_08620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII82_08625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII82_08635	COG2257	FlhB HrpN YscU SpaS Family
GII82_08640	COG0045	succinate-CoA ligase (ADP-forming) activity
GII82_08645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII82_08650	COG0758	DNA mediated transformation
GII82_08655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII82_08660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII82_08665	COG4974	Belongs to the 'phage' integrase family
GII82_08670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII82_08675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII82_08680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII82_08685	COG1815	bacterial-type flagellum-dependent cell motility
GII82_08690	COG1558	bacterial-type flagellum-dependent cell motility
GII82_08695	COG1677	Flagellar hook-basal body complex protein FliE
GII82_08700	COG1766	The M ring may be actively involved in energy transduction
GII82_08705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII82_08710	COG1317	bacterial-type flagellum organization
GII82_08715	COG1157	protein secretion by the type III secretion system
GII82_08720	COG2882	bacterial-type flagellum organization
GII82_08725	COG3334	PFAM MgtE intracellular
GII82_08730	COG3144	bacterial-type flagellum assembly
GII82_08735	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII82_08740	COG4786	Flagellar basal body rod
GII82_08745	COG1582	Flagellar protein (FlbD)
GII82_08750	COG1580	Controls the rotational direction of flagella during chemotaxis
GII82_08755	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII82_08760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII82_08760	COG1776	CheC inhibitor of MCP methylation
GII82_08765	COG2201	protein-glutamate methylesterase activity
GII82_08770	COG3190	flagellar
GII82_08775	COG1338	Plays a role in the flagellum-specific transport system
GII82_08780	COG1987	bacterial-type flagellum assembly
GII82_08785	COG1684	flagellar biosynthetic protein fliR
GII82_08790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII82_08795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII82_08800	COG1419	protein localization to endoplasmic reticulum
GII82_08805	COG0455	bacterial-type flagellum organization
GII82_08810	COG2201	protein-glutamate methylesterase activity
GII82_08815	COG0643	Histidine kinase
GII82_08815	COG2198	Histidine kinase
GII82_08820	COG0835	chemotaxis
GII82_08825	COG1776	CheC inhibitor of MCP methylation
GII82_08830	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII82_08835	COG1191	sigma factor activity
GII82_08845	COG0052	Belongs to the universal ribosomal protein uS2 family
GII82_08850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII82_08855	COG0528	UMP kinase activity
GII82_08860	COG0233	cytoplasmic translational termination
GII82_08865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII82_08870	COG4589	Belongs to the CDS family
GII82_08875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII82_08880	COG0750	zinc metalloprotease
GII82_08885	COG0442	prolyl-tRNA aminoacylation
GII82_08890	COG2176	DNA-directed DNA polymerase activity
GII82_08895	COG0779	Required for maturation of 30S ribosomal subunits
GII82_08900	COG0195	Participates in both transcription termination and antitermination
GII82_08905	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII82_08910	COG1358	cellular component organization or biogenesis
GII82_08915	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII82_08920	COG1550	Protein conserved in bacteria
GII82_08925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII82_08930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII82_08935	COG0196	riboflavin kinase activity
GII82_08940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII82_08945	COG1185	polyribonucleotide nucleotidyltransferase activity
GII82_08950	COG0726	polysaccharide deacetylase
GII82_08955	COG0612	Peptidase, M16
GII82_08960	COG1873	PFAM PRC-barrel domain
GII82_08965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII82_08970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII82_08975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII82_08980	COG0527	aspartate kinase activity
GII82_08985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII82_08990	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII82_08995	COG0740	serine-type endopeptidase activity
GII82_09005	COG4980	gas vesicle protein
GII82_09005	COG1674	ftsk spoiiie
GII82_09010	COG2188	Transcriptional regulator
GII82_09015	COG2814	Major facilitator Superfamily
GII82_09020	COG0612	Peptidase, M16
GII82_09025	COG0612	Peptidase, M16
GII82_09030	COG0300	oxidoreductase activity
GII82_09045	COG1426	Protein conserved in bacteria
GII82_09050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII82_09055	COG1058	Belongs to the CinA family
GII82_09055	COG1546	Belongs to the CinA family
GII82_09060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII82_09065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII82_09070	COG1418	mRNA catabolic process
GII82_09075	COG1692	metallophosphoesterase
GII82_09080	COG2359	stage V sporulation protein S
GII82_09085	COG1063	alcohol dehydrogenase
GII82_09090	COG0156	8-amino-7-oxononanoate synthase activity
GII82_09095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII82_09100	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII82_09110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII82_09115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII82_09130	COG3226	Transcriptional regulator
GII82_09135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII82_09145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII82_09150	COG3321	synthase
GII82_09155	COG2070	2-Nitropropane dioxygenase
GII82_09155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII82_09160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII82_09165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII82_09170	COG3425	synthase
GII82_09175	COG1024	Enoyl-CoA hydratase
GII82_09180	COG1024	Enoyl-CoA hydratase
GII82_09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_09185	COG0300	oxidoreductase activity
GII82_09185	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_09185	COG3321	synthase
GII82_09185	COG0318	PFAM AMP-dependent synthetase and ligase
GII82_09190	COG4221	oxidoreductase activity
GII82_09190	COG3321	synthase
GII82_09190	COG0300	oxidoreductase activity
GII82_09190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII82_09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_09195	COG3321	synthase
GII82_09195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII82_09195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII82_09195	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_09200	COG4221	oxidoreductase activity
GII82_09200	COG3321	synthase
GII82_09200	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_09200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_09205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII82_09205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GII82_09205	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII82_09205	COG3321	synthase
GII82_09210	COG2124	cytochrome p450
GII82_09220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII82_09225	COG1404	Belongs to the peptidase S8 family
GII82_09235	COG4195	phage-related replication protein
GII82_09240	COG1764	response to oxidative stress
GII82_09245	COG2076	Multidrug Resistance protein
GII82_09250	COG2076	Multidrug Resistance protein
GII82_09265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII82_09270	COG1923	regulation of RNA biosynthetic process
GII82_09285	COG1780	Probably involved in ribonucleotide reductase function
GII82_09290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII82_09295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII82_09300	COG4112	unkown
GII82_09305	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII82_09310	COG0464	growth
GII82_09315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII82_09320	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII82_09325	COG0789	Transcriptional regulator
GII82_09330	COG0174	glutamine synthetase
GII82_09365	COG1598	PFAM Uncharacterised protein family UPF0150
GII82_09445	COG0463	Glycosyl transferase, family 2
GII82_09460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII82_09475	COG3655	Transcriptional regulator
GII82_09490	COG0135	phosphoribosylanthranilate isomerase activity
GII82_09500	COG2211	Major facilitator Superfamily
GII82_09505	COG3507	Belongs to the glycosyl hydrolase 43 family
GII82_09510	COG1940	carbohydrate kinase activity
GII82_09515	COG2115	Belongs to the xylose isomerase family
GII82_09520	COG1070	Carbohydrate kinase
GII82_09530	COG1525	nuclease
GII82_09535	COG2814	Major facilitator Superfamily
GII82_09540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII82_09550	COG0756	dUTP diphosphatase activity
GII82_09585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII82_09595	COG3832	glyoxalase III activity
GII82_09640	COG4195	phage-related replication protein
GII82_09650	COG0346	lactoylglutathione lyase activity
GII82_09655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII82_09660	COG1388	LysM domain
GII82_09665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII82_09670	COG4224	UPF0291 protein
GII82_09675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII82_09685	COG3763	UPF0154 protein
GII82_09695	COG0785	Cytochrome C biogenesis protein
GII82_09700	COG2201	protein-glutamate methylesterase activity
GII82_09705	COG4846	Membrane protein involved in cytochrome C biogenesis
GII82_09715	COG0071	Belongs to the small heat shock protein (HSP20) family
GII82_09730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII82_09735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII82_09755	COG0824	Thioesterase
GII82_09765	COG4841	protein insertion into membrane
GII82_09770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII82_09775	COG1832	CoA-binding protein
GII82_09780	COG0187	DNA topoisomerase II activity
GII82_09785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII82_09795	COG1115	amino acid carrier protein
GII82_09810	COG5520	Belongs to the glycosyl hydrolase 30 family
GII82_09815	COG3507	Belongs to the glycosyl hydrolase 43 family
GII82_09820	COG2246	polysaccharide biosynthetic process
GII82_09825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII82_09830	COG0586	Pfam SNARE associated Golgi protein
GII82_09835	COG2404	hydrolase activity, acting on ester bonds
GII82_09840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII82_09845	COG1024	Enoyl-CoA hydratase
GII82_09850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII82_09855	COG0511	ligase activity, forming carbon-carbon bonds
GII82_09860	COG0439	Biotin carboxylase
GII82_09865	COG0318	PFAM AMP-dependent synthetase and ligase
GII82_09870	COG1960	acyl-CoA dehydrogenase activity
GII82_09885	COG1649	PFAM Uncharacterised BCR, COG1649
GII82_09895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_09895	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII82_09900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_09905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_09910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_09915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_09920	COG2027	D-alanyl-D-alanine carboxypeptidase
GII82_09925	COG2017	converts alpha-aldose to the beta-anomer
GII82_09930	COG0534	Mate efflux family protein
GII82_09945	COG0582	viral genome integration into host DNA
GII82_09950	COG0166	Belongs to the GPI family
GII82_09955	COG0405	Gamma-glutamyltransferase
GII82_09960	COG0583	DNA-binding transcription factor activity
GII82_09965	COG0604	alcohol dehydrogenase
GII82_09970	COG0493	'glutamate synthase
GII82_09975	COG0070	glutamate synthase
GII82_09975	COG0067	glutamate synthase
GII82_09975	COG0069	glutamate synthase activity
GII82_09980	COG0583	DNA-binding transcription factor activity
GII82_09985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII82_09990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII82_10000	COG0300	oxidoreductase activity
GII82_10005	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII82_10015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII82_10030	COG2814	Major facilitator Superfamily
GII82_10035	COG1070	Carbohydrate kinase
GII82_10040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII82_10045	COG0243	molybdopterin cofactor binding
GII82_10075	COG0840	transmembrane signaling receptor activity
GII82_10075	COG5278	phosphoserine phosphatase activity
GII82_10080	COG2368	4-hydroxyphenylacetate
GII82_10085	COG4305	rare lipoprotein A
GII82_10090	COG3619	membrane
GII82_10095	COG3866	Pectate lyase
GII82_10100	COG2135	peptidase activity
GII82_10110	COG2140	Oxalate decarboxylase
GII82_10120	COG0456	acetyltransferase
GII82_10140	COG2720	vancomycin resistance protein
GII82_10150	COG3655	Transcriptional regulator
GII82_10155	COG3739	integral membrane protein
GII82_10160	COG0583	DNA-binding transcription factor activity
GII82_10165	COG0697	spore germination
GII82_10175	COG0693	protein deglycase activity
GII82_10180	COG2367	Beta-lactamase
GII82_10205	COG0574	Belongs to the PEP-utilizing enzyme family
GII82_10205	COG3848	Pyruvate phosphate dikinase
GII82_10210	COG0726	polysaccharide deacetylase
GII82_10215	COG2314	TM2 domain
GII82_10340	COG0457	Tetratricopeptide repeat
GII82_10375	COG4282	regulation of fungal-type cell wall biogenesis
GII82_10380	COG1231	oxidoreductase activity
GII82_10385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII82_10390	COG2207	Transcriptional regulator
GII82_10390	COG0662	Cupin 2, conserved barrel domain protein
GII82_10395	COG0456	acetyltransferase
GII82_10400	COG1309	transcriptional regulator
GII82_10405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII82_10410	COG3708	Transcriptional regulator
GII82_10415	COG2378	regulation of single-species biofilm formation
GII82_10425	COG0640	Transcriptional regulator
GII82_10430	COG0741	lytic transglycosylase activity
GII82_10435	COG2322	membrane
GII82_10450	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII82_10455	COG3239	Fatty acid desaturase
GII82_10460	COG4585	Histidine kinase
GII82_10465	COG2197	response regulator
GII82_10470	COG1388	LysM domain
GII82_10470	COG3584	3D domain protein
GII82_10475	COG0514	ATP-dependent DNA helicase (RecQ)
GII82_10485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII82_10490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII82_10505	COG0071	Belongs to the small heat shock protein (HSP20) family
GII82_10530	COG1012	belongs to the aldehyde dehydrogenase family
GII82_10535	COG1657	PFAM Prenyltransferase squalene oxidase
GII82_10540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII82_10545	COG0733	neurotransmitter:sodium symporter activity
GII82_10550	COG0385	Bile acid
GII82_10555	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII82_10560	COG0567	Dehydrogenase, E1 component
GII82_10565	COG4548	von Willebrand factor, type A
GII82_10570	COG0714	Associated with various cellular activities
GII82_10575	COG2032	superoxide dismutase activity
GII82_10580	COG0791	NLP P60 protein
GII82_10580	COG1388	LysM domain
GII82_10585	COG1819	glycosyl
GII82_10590	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII82_10595	COG0534	Mate efflux family protein
GII82_10600	COG1366	Belongs to the anti-sigma-factor antagonist family
GII82_10605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII82_10610	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII82_10620	COG2962	Rard protein
GII82_10635	COG2610	gluconate transmembrane transporter activity
GII82_10640	COG1942	4-Oxalocrotonate Tautomerase
GII82_10645	COG1733	regulation of RNA biosynthetic process
GII82_10650	COG0778	Nitroreductase
GII82_10655	COG0400	carboxylic ester hydrolase activity
GII82_10660	COG0346	lactoylglutathione lyase activity
GII82_10670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII82_10675	COG3409	Peptidoglycan-binding domain 1 protein
GII82_10675	COG0793	Belongs to the peptidase S41A family
GII82_10680	COG2226	methyltransferase
GII82_10690	COG1876	peptidase activity
GII82_10695	COG0813	purine-nucleoside phosphorylase activity
GII82_10710	COG0671	phosphoesterase, PA-phosphatase related
GII82_10730	COG4479	Belongs to the UPF0346 family
GII82_10740	COG1509	lysine 2,3-aminomutase activity
GII82_10745	COG0456	acetyltransferase
GII82_10750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII82_10755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII82_10760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII82_10765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII82_10780	COG0456	acetyltransferase
GII82_10785	COG0463	Glycosyl transferase, family 2
GII82_10800	COG4641	Protein conserved in bacteria
GII82_10805	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII82_10810	COG1086	Polysaccharide biosynthesis protein
GII82_10815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII82_10820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII82_10825	COG1846	Transcriptional regulator
GII82_10830	COG0534	Mate efflux family protein
GII82_10840	COG4698	Protein conserved in bacteria
GII82_10845	COG2755	lipolytic protein G-D-S-L family
GII82_10850	COG1999	signal sequence binding
GII82_10860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII82_10865	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII82_10870	COG1272	protein, Hemolysin III
GII82_10875	COG0204	Acyl-transferase
GII82_10880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII82_10885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII82_10890	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII82_10900	COG2521	methyltransferase
GII82_10900	COG2136	Putative SAM-dependent methyltransferase
GII82_10910	COG0129	dihydroxy-acid dehydratase activity
GII82_10915	COG1413	lyase activity
GII82_10920	COG1418	mRNA catabolic process
GII82_10925	COG0386	Belongs to the glutathione peroxidase family
GII82_10930	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII82_10935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII82_10945	COG1278	Cold shock
GII82_10965	COG0328	RNA-DNA hybrid ribonuclease activity
GII82_10970	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII82_10975	COG0328	RNA-DNA hybrid ribonuclease activity
GII82_10985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII82_11000	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII82_11010	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII82_11015	COG3424	synthase
GII82_11020	COG2233	PERMEase
GII82_11025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII82_11030	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII82_11040	COG0800	Aldolase
GII82_11045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII82_11050	COG1609	Transcriptional regulator
GII82_11055	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII82_11060	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_11065	COG1199	ATP-dependent helicase activity
GII82_11080	COG0116	Belongs to the methyltransferase superfamily
GII82_11095	COG4474	Belongs to the UPF0398 family
GII82_11110	COG3359	exonuclease
GII82_11115	COG1111	helicase
GII82_11115	COG1205	dead DEAH box helicase
GII82_11120	COG2190	(PTS) system
GII82_11125	COG0071	Belongs to the small heat shock protein (HSP20) family
GII82_11160	COG3331	DNA recombination
GII82_11165	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII82_11165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII82_11175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII82_11180	COG3935	DnaD domain protein
GII82_11185	COG0017	Asparaginyl-tRNA synthetase
GII82_11190	COG0436	Aminotransferase
GII82_11195	COG5353	protein conserved in bacteria
GII82_11205	COG1199	ATP-dependent helicase activity
GII82_11205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII82_11210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII82_11215	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII82_11220	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII82_11225	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII82_11225	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII82_11230	COG0617	tRNA 3'-terminal CCA addition
GII82_11235	COG0438	transferase activity, transferring glycosyl groups
GII82_11240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII82_11245	COG1803	Methylglyoxal synthase
GII82_11250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII82_11255	COG1694	Mazg nucleotide pyrophosphohydrolase
GII82_11260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII82_11270	COG4347	Protein of unknown function (DUF1405)
GII82_11275	COG2010	Cytochrome c
GII82_11275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII82_11280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII82_11285	COG0723	plastoquinol--plastocyanin reductase activity
GII82_11295	COG5582	Belongs to the UPF0302 family
GII82_11300	COG0457	Tetratricopeptide repeat
GII82_11305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII82_11310	COG0287	Prephenate dehydrogenase
GII82_11315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GII82_11325	COG0133	tryptophan synthase activity
GII82_11330	COG0135	phosphoribosylanthranilate isomerase activity
GII82_11340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII82_11345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII82_11350	COG4401	Chorismate mutase type I
GII82_11355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII82_11360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII82_11365	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII82_11370	COG0105	UTP biosynthetic process
GII82_11375	COG0142	geranyltranstransferase activity
GII82_11380	COG2226	methyltransferase
GII82_11385	COG0142	geranyltranstransferase activity
GII82_11395	COG0302	gtp cyclohydrolase
GII82_11400	COG0776	regulation of translation
GII82_11405	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII82_11420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII82_11425	COG1160	GTP binding
GII82_11450	COG1304	FMN binding
GII82_11455	COG0539	negative regulation of cytoplasmic translation
GII82_11460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII82_11470	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII82_11475	COG2959	enzyme of heme biosynthesis
GII82_11480	COG3773	Cell wall hydrolase
GII82_11480	COG3409	Peptidoglycan-binding domain 1 protein
GII82_11485	COG2339	peptidase activity
GII82_11490	COG0492	ferredoxin-NADP+ reductase activity
GII82_11495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII82_11500	COG4862	establishment of competence for transformation
GII82_11505	COG1408	metallophosphoesterase
GII82_11515	COG1388	LysM domain
GII82_11520	COG1266	CAAX protease self-immunity
GII82_11525	COG0514	ATP-dependent DNA helicase (RecQ)
GII82_11530	COG4955	Helix-turn-helix domain
GII82_11535	COG1141	Ferredoxin
GII82_11540	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII82_11545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII82_11550	COG0710	3-dehydroquinate dehydratase activity
GII82_11560	COG1595	DNA-templated transcription, initiation
GII82_11565	COG5002	protein histidine kinase activity
GII82_11570	COG0745	RESPONSE REGULATOR receiver
GII82_11575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII82_11580	COG1333	cytochrome c biogenesis protein
GII82_11585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII82_11590	COG1187	pseudouridine synthase activity
GII82_11595	COG0700	Nucleoside recognition
GII82_11600	COG2715	membrane protein required for spore maturation
GII82_11605	COG1686	Belongs to the peptidase S11 family
GII82_11615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII82_11620	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII82_11625	COG1547	Domain of unknown function (DUF309)
GII82_11630	COG0456	acetyltransferase
GII82_11635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII82_11640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII82_11640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII82_11645	COG0307	riboflavin synthase, alpha
GII82_11650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII82_11650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII82_11660	COG0681	Belongs to the peptidase S26 family
GII82_11670	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII82_11695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII82_11700	COG4086	secreted protein
GII82_11705	COG0019	diaminopimelate decarboxylase activity
GII82_11710	COG0697	spore germination
GII82_11725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII82_11745	COG1191	sigma factor activity
GII82_11750	COG2172	sigma factor antagonist activity
GII82_11755	COG1366	Belongs to the anti-sigma-factor antagonist family
GII82_11760	COG1686	Belongs to the peptidase S11 family
GII82_11765	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII82_11770	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII82_11775	COG4974	Belongs to the 'phage' integrase family
GII82_11785	COG0735	belongs to the Fur family
GII82_11790	COG1300	Membrane
GII82_11800	COG0281	malic enzyme
GII82_11805	COG1757	Na H antiporter
GII82_11810	COG1027	Aspartate ammonia-lyase
GII82_11815	COG0252	asparaginase activity
GII82_11820	COG1396	sequence-specific DNA binding
GII82_11825	COG1379	DNA repair
GII82_11830	COG0494	nUDIX hydrolase
GII82_11840	COG0667	Aldo Keto reductase
GII82_11850	COG1073	alpha beta
GII82_11860	COG4918	Iron-sulphur cluster biosynthesis
GII82_11865	COG0456	acetyltransferase
GII82_11865	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII82_11870	COG2329	Antibiotic biosynthesis monooxygenase
GII82_11875	COG0456	acetyltransferase
GII82_11885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII82_11895	COG2211	Major facilitator Superfamily
GII82_11900	COG0346	lactoylglutathione lyase activity
GII82_11905	COG1072	(Pantothenic acid kinase))
GII82_11910	COG3048	D-serine ammonia-lyase activity
GII82_11915	COG0300	oxidoreductase activity
GII82_11920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII82_11925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII82_11930	COG4187	Peptidase family M20/M25/M40
GII82_11935	COG1902	pentaerythritol trinitrate reductase activity
GII82_11940	COG0596	Alpha beta hydrolase
GII82_11950	COG1234	tRNA 3'-trailer cleavage
GII82_11955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII82_11960	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII82_11965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII82_11975	COG0706	membrane insertase activity
GII82_11980	COG3361	conserved protein (COG2071)
GII82_11985	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII82_11990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII82_11995	COG0346	lactoylglutathione lyase activity
GII82_12005	COG1376	ErfK ybiS ycfS ynhG family protein
GII82_12010	COG4129	membrane
GII82_12015	COG1126	abc transporter atp-binding protein
GII82_12020	COG0765	amino acid transport
GII82_12025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII82_12035	COG1597	lipid kinase activity
GII82_12040	COG2814	Major facilitator Superfamily
GII82_12045	COG0789	Transcriptional regulator
GII82_12045	COG4978	Transcriptional regulator
GII82_12050	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII82_12055	COG0022	dehydrogenase e1 component
GII82_12060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII82_12065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII82_12070	COG3426	butyrate kinase activity
GII82_12075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII82_12080	COG0280	phosphate acetyltransferase
GII82_12085	COG3290	protein histidine kinase activity
GII82_12085	COG3829	transcription factor binding
GII82_12095	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII82_12100	COG2079	MmgE PrpD family protein
GII82_12105	COG0372	Belongs to the citrate synthase family
GII82_12110	COG1960	acyl-CoA dehydrogenase activity
GII82_12115	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII82_12120	COG0183	Belongs to the thiolase family
GII82_12125	COG0584	glycerophosphoryl diester phosphodiesterase
GII82_12130	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII82_12145	COG1902	pentaerythritol trinitrate reductase activity
GII82_12150	COG0745	RESPONSE REGULATOR receiver
GII82_12155	COG0750	zinc metalloprotease
GII82_12160	COG0497	DNA recombination
GII82_12165	COG1438	arginine binding
GII82_12170	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII82_12175	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII82_12180	COG0142	geranyltranstransferase activity
GII82_12185	COG1722	exodeoxyribonuclease VII activity
GII82_12190	COG1570	exodeoxyribonuclease VII activity
GII82_12195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII82_12200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII82_12205	COG1302	Protein conserved in bacteria
GII82_12210	COG0439	Biotin carboxylase
GII82_12215	COG0511	ligase activity, forming carbon-carbon bonds
GII82_12255	COG3854	ATPases associated with a variety of cellular activities
GII82_12265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII82_12270	COG0006	proline dipeptidase activity
GII82_12275	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII82_12285	COG3872	metal-dependent enzyme
GII82_12295	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII82_12300	COG1321	iron dependent repressor
GII82_12305	COG0095	Lipoate-protein ligase
GII82_12310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII82_12315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII82_12320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII82_12325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII82_12330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII82_12345	COG1396	sequence-specific DNA binding
GII82_12355	COG0681	Belongs to the peptidase S26 family
GII82_12380	COG4940	Competence protein ComGF
GII82_12390	COG4970	Tfp pilus assembly protein FimT
GII82_12395	COG4537	Required for transformation and DNA binding
GII82_12400	COG1459	type II secretion system
GII82_12405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII82_12410	COG0517	IMP dehydrogenase activity
GII82_12415	COG0598	Magnesium transport protein CorA
GII82_12420	COG1253	flavin adenine dinucleotide binding
GII82_12425	COG1366	Belongs to the anti-sigma-factor antagonist family
GII82_12435	COG1393	Belongs to the ArsC family
GII82_12445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII82_12455	COG0011	TIGRFAM Protein of
GII82_12465	COG2866	Carboxypeptidase
GII82_12470	COG1368	sulfuric ester hydrolase activity
GII82_12475	COG1940	carbohydrate kinase activity
GII82_12480	COG4483	Protein conserved in bacteria
GII82_12485	COG0457	Tetratricopeptide repeat
GII82_12485	COG0705	Rhomboid family
GII82_12495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII82_12500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII82_12505	COG0438	transferase activity, transferring glycosyl groups
GII82_12520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII82_12525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII82_12530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII82_12535	COG0581	inorganic phosphate transmembrane transporter activity
GII82_12540	COG0573	inorganic phosphate transmembrane transporter activity
GII82_12545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII82_12555	COG0477	Major facilitator Superfamily
GII82_12560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII82_12565	COG2839	Protein conserved in bacteria
GII82_12570	COG5521	maltodextrose utilization protein MalA
GII82_12575	COG1388	LysM domain
GII82_12580	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII82_12585	COG4709	membrane
GII82_12590	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII82_12595	COG0735	belongs to the Fur family
GII82_12600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII82_12610	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII82_12615	COG0513	Belongs to the DEAD box helicase family
GII82_12625	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII82_12630	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII82_12635	COG2384	SAM-dependent methyltransferase
GII82_12640	COG2010	Cytochrome c
GII82_12645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII82_12650	COG0358	DNA primase activity
GII82_12655	COG1671	Belongs to the UPF0178 family
GII82_12660	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII82_12665	COG0517	IMP dehydrogenase activity
GII82_12670	COG0751	glycine-tRNA ligase activity
GII82_12675	COG0752	glycyl-tRNA synthetase alpha subunit
GII82_12680	COG1381	Involved in DNA repair and RecF pathway recombination
GII82_12690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII82_12695	COG0295	cytidine deaminase activity
GII82_12700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII82_12705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII82_12710	COG1480	7TM receptor with intracellular HD hydrolase
GII82_12715	COG1702	phosphate starvation-inducible protein PhoH
GII82_12720	COG0561	phosphatase activity
GII82_12735	COG4864	UPF0365 protein
GII82_12740	COG1030	water channel activity
GII82_12745	COG1610	YqeY-like protein
GII82_12750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GII82_12755	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII82_12760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII82_12765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII82_12770	COG2264	protein methyltransferase activity
GII82_12775	COG0484	heat shock protein binding
GII82_12780	COG0443	Heat shock 70 kDa protein
GII82_12785	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII82_12790	COG1420	regulation of RNA biosynthetic process
GII82_12795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII82_12800	COG0481	GTPase activity
GII82_12810	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII82_12815	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII82_12820	COG0268	Binds directly to 16S ribosomal RNA
GII82_12825	COG1466	dna polymerase III delta subunit
GII82_12840	COG0658	competence protein
GII82_12840	COG2333	competence protein COMEC
GII82_12845	COG2131	deaminase
GII82_12850	COG1596	polysaccharide export
GII82_12850	COG1555	photosystem II stabilization
GII82_12855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII82_12860	COG2226	methyltransferase
GII82_12865	COG0799	negative regulation of ribosome biogenesis
GII82_12870	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII82_12875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII82_12880	COG1534	Rna-binding protein
GII82_12885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII82_12890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII82_12895	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII82_12905	COG2755	lipolytic protein G-D-S-L family
GII82_12910	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII82_12910	COG3409	Peptidoglycan-binding domain 1 protein
GII82_12915	COG0398	Pfam SNARE associated Golgi protein
GII82_12930	COG3209	COG3209 Rhs family protein
GII82_12940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII82_12955	COG2323	membrane
GII82_12960	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII82_12965	COG0730	response to heat
GII82_12970	COG0425	Belongs to the sulfur carrier protein TusA family
GII82_12975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII82_12975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII82_12985	COG0425	Belongs to the sulfur carrier protein TusA family
GII82_12985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII82_12995	COG2210	Belongs to the sulfur carrier protein TusA family
GII82_13000	COG1937	Protein conserved in bacteria
GII82_13005	COG0662	Cupin 2, conserved barrel domain protein
GII82_13015	COG0457	Tetratricopeptide repeat
GII82_13030	COG5444	nuclease activity
GII82_13055	COG3409	Peptidoglycan-binding domain 1 protein
GII82_13055	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII82_13060	COG4824	toxin secretion phage lysis holin
GII82_13090	COG3778	Protein conserved in bacteria
GII82_13095	COG3299	homolog of phage Mu protein gp47
GII82_13100	COG3628	GPW Gp25 family protein
GII82_13110	COG4193	domain, Protein
GII82_13115	COG1652	LysM domain
GII82_13120	COG3953	SLT domain
GII82_13120	COG5280	Phage tail tape measure protein TP901
GII82_13180	COG4653	Phage capsid family
GII82_13185	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII82_13195	COG2369	cell adhesion
GII82_13200	COG5518	Phage portal protein
GII82_13205	COG1783	phage Terminase large subunit
GII82_13210	COG5484	DNA packaging
GII82_13220	COG1335	isochorismatase
GII82_13255	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GII82_13265	COG1484	DNA-dependent DNA replication
GII82_13270	COG3935	DnaD domain protein
GII82_13275	COG3723	Recombinational DNA repair protein, rece pathway
GII82_13280	COG5377	YqaJ viral recombinase family
GII82_13315	COG3620	sequence-specific DNA binding
GII82_13325	COG0563	adenylate kinase activity
GII82_13330	COG2856	Zn peptidase
GII82_13345	COG0642	Histidine kinase
GII82_13345	COG5002	protein histidine kinase activity
GII82_13350	COG0745	RESPONSE REGULATOR receiver
GII82_13355	COG2311	Membrane
GII82_13365	COG0454	-acetyltransferase
GII82_13370	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII82_13380	COG0730	response to heat
GII82_13385	COG0425	Belongs to the sulfur carrier protein TusA family
GII82_13390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII82_13390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII82_13400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII82_13400	COG0425	Belongs to the sulfur carrier protein TusA family
GII82_13405	COG2210	Belongs to the sulfur carrier protein TusA family
GII82_13410	COG1937	Protein conserved in bacteria
GII82_13415	COG0662	Cupin 2, conserved barrel domain protein
GII82_13425	COG0789	Transcriptional regulator
GII82_13425	COG4978	Transcriptional regulator
GII82_13430	COG2814	Major facilitator Superfamily
GII82_13435	COG0456	acetyltransferase
GII82_13440	COG1253	flavin adenine dinucleotide binding
GII82_13450	COG0697	spore germination
GII82_13455	COG0583	DNA-binding transcription factor activity
GII82_13460	COG2072	flavoprotein involved in K transport
GII82_13465	COG1230	cation diffusion facilitator family transporter
GII82_13470	COG1942	4-Oxalocrotonate Tautomerase
GII82_13475	COG0583	DNA-binding transcription factor activity
GII82_13485	COG1114	Component of the transport system for branched-chain amino acids
GII82_13490	COG1687	branched-chain amino acid
GII82_13495	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII82_13500	COG1522	sequence-specific DNA binding
GII82_13510	COG2124	cytochrome p450
GII82_13515	COG1335	isochorismatase
GII82_13525	COG2318	DinB family
GII82_13535	COG2070	2-Nitropropane dioxygenase
GII82_13540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII82_13550	COG2186	Transcriptional regulator
GII82_13565	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_13570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII82_13575	COG3959	Transketolase, thiamine diphosphate binding domain
GII82_13585	COG0789	Transcriptional regulator
GII82_13585	COG4978	Transcriptional regulator
GII82_13590	COG2315	Protein conserved in bacteria
GII82_13600	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII82_13605	COG1595	DNA-templated transcription, initiation
GII82_13610	COG0667	Aldo Keto reductase
GII82_13615	COG2851	Citrate transporter
GII82_13620	COG0583	DNA-binding transcription factor activity
GII82_13625	COG2828	Protein conserved in bacteria
GII82_13630	COG3409	Peptidoglycan-binding domain 1 protein
GII82_13635	COG5566	PFAM Mor transcription activator
GII82_13640	COG0596	Alpha beta hydrolase
GII82_13645	COG4991	sh3 domain protein
GII82_13650	COG4991	sh3 domain protein
GII82_13660	COG0346	lactoylglutathione lyase activity
GII82_13670	COG5577	PFAM Coat F domain
GII82_13675	COG1063	alcohol dehydrogenase
GII82_13685	COG5577	PFAM Coat F domain
GII82_13690	COG0789	Transcriptional regulator
GII82_13700	COG1064	alcohol dehydrogenase
GII82_13705	COG0693	protein deglycase activity
GII82_13710	COG1621	beta-fructofuranosidase activity
GII82_13715	COG3716	PTS system mannose fructose sorbose family IID component
GII82_13720	COG3715	PTS system
GII82_13725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII82_13730	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII82_13735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII82_13735	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII82_13745	COG1113	amino acid transport
GII82_13750	COG1280	lysine exporter protein (LysE YggA)
GII82_13755	COG1378	Sugar-specific transcriptional regulator TrmB
GII82_13760	COG1595	DNA-templated transcription, initiation
GII82_13780	COG2124	cytochrome p450
GII82_13780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII82_13785	COG1309	transcriptional regulator
GII82_13790	COG2226	methyltransferase
GII82_13805	COG2116	formate transmembrane transporter activity
GII82_13810	COG5609	conserved protein (DUF2294)
GII82_13815	COG3383	formate dehydrogenase (NAD+) activity
GII82_13820	COG2427	Protein of unknown function (DUF1641)
GII82_13830	COG0626	cystathionine gamma-synthase activity
GII82_13835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII82_13840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII82_13845	COG2226	methyltransferase
GII82_13860	COG0768	penicillin binding
GII82_13865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII82_13870	COG0572	uridine kinase
GII82_13890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII82_13895	COG3906	Belongs to the UPF0473 family
GII82_13900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII82_13905	COG4472	Bacterial protein of unknown function (DUF965)
GII82_13910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII82_13915	COG0628	permease
GII82_13920	COG1126	abc transporter atp-binding protein
GII82_13925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII82_13930	COG0765	amino acid transport
GII82_13935	COG0765	amino acid transport
GII82_13950	COG3881	PFAM PRC-barrel domain
GII82_13955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII82_13960	COG0457	Tetratricopeptide repeat
GII82_13965	COG0482	sulfurtransferase activity
GII82_13970	COG1104	cysteine desulfurase activity
GII82_13975	COG1959	2 iron, 2 sulfur cluster binding
GII82_13980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII82_13985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII82_13995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII82_14000	COG0124	histidyl-tRNA synthetase
GII82_14010	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII82_14010	COG3103	Sh3 type 3 domain protein
GII82_14010	COG4991	sh3 domain protein
GII82_14015	COG1490	D-aminoacyl-tRNA deacylase activity
GII82_14020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII82_14025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII82_14030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII82_14030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII82_14035	COG5416	Lipopolysaccharide assembly protein A domain
GII82_14040	COG0490	domain, Protein
GII82_14045	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII82_14045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII82_14055	COG2244	polysaccharide biosynthetic process
GII82_14060	COG2323	membrane
GII82_14070	COG1862	Preprotein translocase
GII82_14075	COG0343	queuine tRNA-ribosyltransferase activity
GII82_14080	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII82_14090	COG2255	four-way junction helicase activity
GII82_14095	COG0632	four-way junction helicase activity
GII82_14105	COG2814	Major facilitator Superfamily
GII82_14110	COG0673	inositol 2-dehydrogenase activity
GII82_14115	COG2112	serine threonine protein kinase
GII82_14135	COG1115	amino acid carrier protein
GII82_14140	COG0217	transcriptional regulatory protein
GII82_14150	COG1388	LysM domain
GII82_14155	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII82_14160	COG0157	Belongs to the NadC ModD family
GII82_14165	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII82_14170	COG1104	cysteine desulfurase activity
GII82_14175	COG1827	regulation of RNA biosynthetic process
GII82_14180	COG0077	Prephenate dehydratase
GII82_14185	COG4492	Belongs to the UPF0735 family
GII82_14190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII82_14195	COG3290	protein histidine kinase activity
GII82_14205	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII82_14210	COG2868	ribosomal protein
GII82_14215	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII82_14220	COG1994	Peptidase M50
GII82_14225	COG0739	heme binding
GII82_14230	COG2894	cell division
GII82_14235	COG0850	regulation of cytokinetic process
GII82_14240	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII82_14245	COG1792	Involved in formation and maintenance of cell shape
GII82_14250	COG1077	Cell shape determining protein MreB Mrl
GII82_14255	COG2003	Belongs to the UPF0758 family
GII82_14260	COG0424	maF-like protein
GII82_14270	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII82_14275	COG0285	dihydrofolate synthase activity
GII82_14280	COG0525	valine-tRNA ligase activity
GII82_14290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII82_14295	COG1388	LysM domain
GII82_14300	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII82_14305	COG0113	porphobilinogen synthase activity
GII82_14310	COG1587	Uroporphyrinogen-III synthase
GII82_14315	COG0181	hydroxymethylbilane synthase activity
GII82_14320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII82_14325	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII82_14335	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII82_14340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII82_14345	COG0470	DNA polymerase III
GII82_14345	COG1067	ATP-dependent peptidase activity
GII82_14350	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII82_14355	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII82_14360	COG0457	Tetratricopeptide repeat
GII82_14360	COG1477	protein flavinylation
GII82_14365	COG0066	3-isopropylmalate dehydratase activity
GII82_14370	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII82_14375	COG0473	3-isopropylmalate dehydrogenase activity
GII82_14380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII82_14385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII82_14390	COG0440	acetolactate synthase activity
GII82_14395	COG0028	Belongs to the TPP enzyme family
GII82_14405	COG0454	-acetyltransferase
GII82_14410	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII82_14420	COG0622	Phosphoesterase
GII82_14425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII82_14430	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII82_14435	COG5401	PFAM Sporulation and spore germination
GII82_14440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII82_14445	COG1846	Transcriptional regulator
GII82_14450	COG2197	response regulator
GII82_14455	COG0824	Thioesterase
GII82_14460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII82_14465	COG1053	succinate dehydrogenase
GII82_14470	COG2009	succinate dehydrogenase
GII82_14475	COG1719	4-vinyl reductase, 4VR
GII82_14480	COG0527	aspartate kinase activity
GII82_14485	COG0322	excinuclease ABC activity
GII82_14490	COG3118	belongs to the thioredoxin family
GII82_14495	COG3534	alpha-L-arabinofuranosidase
GII82_14500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII82_14505	COG2086	electron transfer activity
GII82_14510	COG1024	Enoyl-CoA hydratase
GII82_14515	COG1309	transcriptional regulator
GII82_14520	COG0318	PFAM AMP-dependent synthetase and ligase
GII82_14525	COG3766	membrane
GII82_14530	COG1193	negative regulation of DNA recombination
GII82_14535	COG1796	DNA polymerase
GII82_14535	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII82_14540	COG1286	toxin biosynthetic process
GII82_14545	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII82_14550	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII82_14555	COG0072	phenylalanine-tRNA ligase activity
GII82_14555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII82_14560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII82_14570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII82_14580	COG3835	regulator
GII82_14585	COG0277	FAD linked oxidase domain protein
GII82_14590	COG0247	lactate metabolic process
GII82_14605	COG1966	Carbon starvation protein
GII82_14610	COG3534	alpha-L-arabinofuranosidase
GII82_14615	COG0395	ABC-type sugar transport system, permease component
GII82_14620	COG1175	transmembrane transport
GII82_14625	COG1653	transport
GII82_14630	COG0371	Dehydrogenase
GII82_14635	COG0647	UMP catabolic process
GII82_14640	COG0235	Class ii aldolase
GII82_14645	COG1069	ribulokinase activity
GII82_14650	COG2160	L-arabinose isomerase activity
GII82_14655	COG3507	Belongs to the glycosyl hydrolase 43 family
GII82_14660	COG1363	Peptidase, m42
GII82_14670	COG3326	Membrane
GII82_14675	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII82_14680	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII82_14685	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII82_14695	COG1346	cytolysis
GII82_14700	COG1380	Effector of murein hydrolase LrgA
GII82_14705	COG3279	Response regulator of the LytR AlgR family
GII82_14710	COG3275	phosphorelay sensor kinase activity
GII82_14720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII82_14730	COG0398	Pfam SNARE associated Golgi protein
GII82_14735	COG1484	DNA-dependent DNA replication
GII82_14740	COG3611	Membrane attachment protein
GII82_14745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII82_14750	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII82_14755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII82_14760	COG1733	regulation of RNA biosynthetic process
GII82_14765	COG2814	Major facilitator Superfamily
GII82_14770	COG0656	L-ascorbic acid biosynthetic process
GII82_14775	COG0237	dephospho-CoA kinase activity
GII82_14780	COG1971	Probably functions as a manganese efflux pump
GII82_14785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII82_14790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII82_14790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII82_14795	COG5002	protein histidine kinase activity
GII82_14800	COG0745	RESPONSE REGULATOR receiver
GII82_14805	COG0039	L-malate dehydrogenase activity
GII82_14810	COG0538	isocitrate dehydrogenase activity
GII82_14815	COG0372	Belongs to the citrate synthase family
GII82_14820	COG2707	UPF0756 membrane protein
GII82_14825	COG0628	permease
GII82_14830	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII82_14835	COG0469	pyruvate kinase activity
GII82_14840	COG0205	6-phosphofructokinase activity
GII82_14845	COG0825	malonyl-CoA metabolic process
GII82_14850	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII82_14855	COG0281	malic enzyme
GII82_14860	COG0587	DNA-directed DNA polymerase activity
GII82_14880	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII82_14890	COG4109	DRTGG domain
GII82_14895	COG0730	response to heat
GII82_14900	COG1473	amidohydrolase
GII82_14905	COG0196	riboflavin kinase activity
GII82_14910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII82_14915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII82_14920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII82_14925	COG1126	abc transporter atp-binding protein
GII82_14930	COG0765	amino acid transport
GII82_14935	COG0765	amino acid transport
GII82_14940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII82_14945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII82_14950	COG0454	-acetyltransferase
GII82_14955	COG0583	DNA-binding transcription factor activity
GII82_14960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII82_14965	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_14975	COG0165	Argininosuccinate lyase
GII82_14980	COG0137	argininosuccinate synthase activity
GII82_14985	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII82_14990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII82_15000	COG0827	DNA restriction-modification system
GII82_15005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII82_15010	COG3874	Sporulation protein YtfJ
GII82_15020	COG1714	RDD family
GII82_15025	COG0616	signal peptide processing
GII82_15030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII82_15035	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII82_15040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII82_15050	COG0301	tRNA thio-modification
GII82_15055	COG1104	cysteine desulfurase activity
GII82_15060	COG1114	Component of the transport system for branched-chain amino acids
GII82_15065	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII82_15070	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII82_15075	COG1309	transcriptional regulator
GII82_15080	COG1956	GAF domain-containing protein
GII82_15085	COG2199	diguanylate cyclase activity
GII82_15085	COG2203	Gaf domain
GII82_15095	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII82_15100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII82_15105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII82_15110	COG0454	-acetyltransferase
GII82_15115	COG0517	IMP dehydrogenase activity
GII82_15120	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII82_15125	COG1360	Flagellar Motor Protein
GII82_15130	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII82_15135	COG1609	Transcriptional regulator
GII82_15140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII82_15140	COG1605	Chorismate mutase
GII82_15145	COG3118	belongs to the thioredoxin family
GII82_15150	COG4980	gas vesicle protein
GII82_15155	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII82_15160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII82_15165	COG1674	ftsk spoiiie
GII82_15170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII82_15175	COG4848	Belongs to the UPF0354 family
GII82_15180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII82_15195	COG1363	Peptidase, m42
GII82_15200	COG5584	Small secreted protein
GII82_15205	COG0281	malic enzyme
GII82_15210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII82_15215	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII82_15225	COG0510	thiamine kinase activity
GII82_15230	COG1523	belongs to the glycosyl hydrolase 13 family
GII82_15235	COG1597	lipid kinase activity
GII82_15245	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII82_15250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII82_15255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII82_15260	COG2252	PERMEase
GII82_15265	COG4473	ABC transporter
GII82_15270	COG1131	(ABC) transporter
GII82_15275	COG1349	DNA-binding transcription factor activity
GII82_15280	COG1187	pseudouridine synthase activity
GII82_15285	COG2244	polysaccharide biosynthetic process
GII82_15290	COG2081	HI0933 family
GII82_15295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII82_15305	COG5578	integral membrane protein
GII82_15310	COG0673	inositol 2-dehydrogenase activity
GII82_15315	COG1653	transport
GII82_15320	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII82_15325	COG4209	transmembrane transport
GII82_15330	COG2207	Transcriptional regulator
GII82_15335	COG1653	transport
GII82_15340	COG0395	ABC-type sugar transport system, permease component
GII82_15345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII82_15350	COG2124	cytochrome p450
GII82_15355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII82_15365	COG0156	8-amino-7-oxononanoate synthase activity
GII82_15370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII82_15380	COG1073	alpha beta
GII82_15405	COG1486	melibiose metabolic process
GII82_15410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII82_15415	COG0495	leucyl-tRNA aminoacylation
GII82_15425	COG2202	Pas domain
GII82_15425	COG1366	Belongs to the anti-sigma-factor antagonist family
GII82_15430	COG2814	Major facilitator Superfamily
GII82_15435	COG2433	Pfam Transposase IS66
GII82_15440	COG0577	efflux transmembrane transporter activity
GII82_15445	COG1136	(ABC) transporter
GII82_15450	COG2205	protein histidine kinase activity
GII82_15455	COG0745	RESPONSE REGULATOR receiver
GII82_15460	COG0577	efflux transmembrane transporter activity
GII82_15465	COG1136	(ABC) transporter
GII82_15480	COG1131	(ABC) transporter
GII82_15485	COG1725	Transcriptional regulator
GII82_15500	COG1242	4 iron, 4 sulfur cluster binding
GII82_15505	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII82_15515	COG2267	carboxylic ester hydrolase activity
GII82_15520	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII82_15525	COG1113	amino acid transport
GII82_15530	COG0367	asparagine synthase
GII82_15535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII82_15540	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII82_15550	COG1506	peptidase
GII82_15555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII82_15560	COG1116	anion transmembrane transporter activity
GII82_15565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII82_15570	COG0494	nUDIX hydrolase
GII82_15575	COG4824	toxin secretion phage lysis holin
GII82_15580	COG0783	Belongs to the Dps family
GII82_15595	COG1854	S-ribosylhomocysteine lyase activity
GII82_15600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII82_15605	COG0288	reversible hydration of carbon dioxide
GII82_15610	COG0254	rRNA binding
GII82_15615	COG1271	oxidase subunit
GII82_15620	COG1294	oxidase, subunit
GII82_15630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII82_15635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII82_15635	COG1321	iron dependent repressor
GII82_15640	COG1121	(ABC) transporter
GII82_15645	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII82_15650	COG4948	Mandelate Racemase Muconate Lactonizing
GII82_15655	COG0318	PFAM AMP-dependent synthetase and ligase
GII82_15660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII82_15665	COG0596	Alpha beta hydrolase
GII82_15670	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII82_15675	COG1169	isochorismate synthase
GII82_15680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII82_15685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII82_15690	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII82_15695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII82_15700	COG0438	transferase activity, transferring glycosyl groups
GII82_15710	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII82_15715	COG0438	transferase activity, transferring glycosyl groups
GII82_15720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII82_15725	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GII82_15730	COG0058	SHG alpha-glucan phosphorylase activity
GII82_15735	COG0297	glycogen (starch) synthase activity
GII82_15740	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII82_15745	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII82_15750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII82_15875	COG3859	Proton-coupled thiamine transporter YuaJ
GII82_15880	COG1247	-acetyltransferase
GII82_15885	COG2268	Band 7 protein
GII82_15890	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII82_15895	COG2318	DinB family
GII82_15905	COG1454	alcohol dehydrogenase
GII82_15915	COG1510	regulation of RNA biosynthetic process
GII82_15925	COG0569	domain protein
GII82_15930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII82_15935	COG4682	membrane
GII82_15940	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII82_15945	COG0477	Major facilitator Superfamily
GII82_15950	COG5553	Cysteine dioxygenase type I
GII82_15960	COG1968	undecaprenyl-diphosphatase activity
GII82_15965	COG0628	permease
GII82_15970	COG0673	inositol 2-dehydrogenase activity
GII82_15975	COG4806	L-rhamnose isomerase
GII82_15980	COG3254	rhamnose metabolic process
GII82_15985	COG1070	Carbohydrate kinase
GII82_15990	COG1349	DNA-binding transcription factor activity
GII82_15995	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_15995	COG3347	Dehydrogenase
GII82_16000	COG0840	transmembrane signaling receptor activity
GII82_16005	COG0840	transmembrane signaling receptor activity
GII82_16010	COG0840	transmembrane signaling receptor activity
GII82_16015	COG0840	transmembrane signaling receptor activity
GII82_16030	COG0432	Pfam Uncharacterised protein family UPF0047
GII82_16040	COG0366	Alpha amylase catalytic
GII82_16045	COG1253	flavin adenine dinucleotide binding
GII82_16050	COG2738	Putative neutral zinc metallopeptidase
GII82_16065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII82_16080	COG0166	Belongs to the GPI family
GII82_16085	COG1979	alcohol dehydrogenase
GII82_16090	COG1979	alcohol dehydrogenase
GII82_16095	COG2155	Conserved Protein
GII82_16100	COG1098	S1 RNA binding domain
GII82_16105	COG0436	Aminotransferase
GII82_16110	COG1522	sequence-specific DNA binding
GII82_16115	COG2267	carboxylic ester hydrolase activity
GII82_16125	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII82_16130	COG2205	protein histidine kinase activity
GII82_16140	COG5018	Exonuclease
GII82_16150	COG2814	Major facilitator Superfamily
GII82_16155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII82_16160	COG3011	Protein conserved in bacteria
GII82_16170	COG3290	protein histidine kinase activity
GII82_16175	COG4565	transcriptional regulatory protein
GII82_16200	COG3493	citrate carrier protein
GII82_16210	COG2111	Na H antiporter
GII82_16210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII82_16215	COG2111	Na H antiporter
GII82_16220	COG1006	Multisubunit Na H antiporter MnhC subunit
GII82_16225	COG0651	ATP synthesis coupled electron transport
GII82_16230	COG1863	multisubunit Na H antiporter MnhE subunit
GII82_16235	COG2212	antiporter activity
GII82_16240	COG1320	monovalent cation:proton antiporter activity
GII82_16245	COG2050	protein possibly involved in aromatic compounds catabolism
GII82_16250	COG2197	response regulator
GII82_16255	COG4585	Histidine kinase
GII82_16265	COG0142	geranyltranstransferase activity
GII82_16285	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII82_16290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII82_16295	COG1335	isochorismatase
GII82_16300	COG5506	Protein of unknown function (DUF1694)
GII82_16315	COG0628	permease
GII82_16330	COG1418	mRNA catabolic process
GII82_16335	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_16345	COG1511	domain protein
GII82_16350	COG0433	COG0433 Predicted ATPase
GII82_16350	COG1674	ftsk spoiiie
GII82_16355	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII82_16360	COG5417	Belongs to the EsaB family
GII82_16365	COG4842	Belongs to the WXG100 family
GII82_16370	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII82_16370	COG2508	Transcriptional regulator
GII82_16375	COG0686	Belongs to the AlaDH PNT family
GII82_16380	COG5634	Uncharacterized conserved protein (DUF2278)
GII82_16385	COG3251	PFAM MbtH domain protein
GII82_16390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_16395	COG3433	isochorismatase activity
GII82_16395	COG1535	isochorismatase
GII82_16400	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII82_16410	COG1169	isochorismate synthase
GII82_16415	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_16420	COG2819	hydrolase of the alpha beta superfamily
GII82_16425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII82_16430	COG1268	BioY protein
GII82_16435	COG2056	Na+-H+ antiporter family
GII82_16440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII82_16445	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII82_16450	COG3584	3D domain protein
GII82_16465	COG1252	NADH dehydrogenase
GII82_16470	COG0492	ferredoxin-NADP+ reductase activity
GII82_16480	COG0516	GMP reductase activity
GII82_16485	COG2808	Putative FMN-binding domain
GII82_16490	COG0456	acetyltransferase
GII82_16495	COG0316	Belongs to the HesB IscA family
GII82_16500	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII82_16505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII82_16510	COG4844	belongs to the
GII82_16515	COG1252	NADH dehydrogenase
GII82_16520	COG4837	Protein of unknown function (DUF1462)
GII82_16525	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII82_16530	COG1506	peptidase
GII82_16530	COG0823	Involved in the tonB-independent uptake of proteins
GII82_16530	COG4946	Tricorn protease homolog
GII82_16535	COG0083	homoserine kinase activity
GII82_16540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII82_16545	COG0460	homoserine dehydrogenase
GII82_16550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII82_16555	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII82_16560	COG0647	UMP catabolic process
GII82_16565	COG2445	Protein of unknown function DUF86
GII82_16570	COG4470	Protein conserved in bacteria
GII82_16580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII82_16585	COG0739	heme binding
GII82_16595	COG3377	Domain of unknown function (DUF1805)
GII82_16600	COG0737	Belongs to the 5'-nucleotidase family
GII82_16605	COG0730	response to heat
GII82_16610	COG1801	Protein of unknown function DUF72
GII82_16620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII82_16625	COG2508	Transcriptional regulator
GII82_16630	COG2233	PERMEase
GII82_16635	COG2233	PERMEase
GII82_16640	COG3648	Uricase
GII82_16640	COG3195	allantoin biosynthetic process
GII82_16645	COG2351	hydroxyisourate hydrolase activity
GII82_16655	COG2080	2 iron, 2 sulfur cluster binding
GII82_16660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII82_16665	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII82_16670	COG2068	MobA-Related Protein
GII82_16675	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII82_16680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII82_16685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII82_16695	COG2356	endonuclease I
GII82_16700	COG3842	ATPase activity
GII82_16705	COG2188	Transcriptional regulator
GII82_16710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII82_16715	COG0395	ABC-type sugar transport system, permease component
GII82_16720	COG1175	transmembrane transport
GII82_16725	COG1653	transport
GII82_16730	COG2222	sugar isomerase
GII82_16735	COG0322	excinuclease ABC activity
GII82_16740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII82_16755	COG0346	lactoylglutathione lyase activity
GII82_16760	COG0640	Transcriptional regulator
GII82_16765	COG0719	Fe-S assembly protein
GII82_16770	COG0822	iron-sulfur transferase activity
GII82_16775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII82_16780	COG0719	Fe-S assembly protein
GII82_16785	COG0396	ATPase activity
GII82_16795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII82_16800	COG1464	Belongs to the NlpA lipoprotein family
GII82_16805	COG2011	ABC-type metal ion transport system permease component
GII82_16810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII82_16820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII82_16825	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII82_16835	COG0509	glycine decarboxylation via glycine cleavage system
GII82_16840	COG1393	Belongs to the ArsC family
GII82_16845	COG1960	acyl-CoA dehydrogenase activity
GII82_16850	COG0183	Belongs to the thiolase family
GII82_16855	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII82_16855	COG1024	Enoyl-CoA hydratase
GII82_16865	COG0506	proline dehydrogenase activity
GII82_16875	COG5577	PFAM Coat F domain
GII82_16880	COG1846	Transcriptional regulator
GII82_16885	COG0477	Major facilitator Superfamily
GII82_16890	COG1942	4-Oxalocrotonate Tautomerase
GII82_16895	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_16900	COG0583	DNA-binding transcription factor activity
GII82_16910	COG1120	ATPase activity
GII82_16925	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_16930	COG0783	Belongs to the Dps family
GII82_16935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII82_16940	COG0745	RESPONSE REGULATOR receiver
GII82_16945	COG2770	Histidine kinase
GII82_16945	COG2205	protein histidine kinase activity
GII82_16955	COG1309	transcriptional regulator
GII82_16960	COG0114	fumarate hydratase activity
GII82_16970	COG0697	spore germination
GII82_16975	COG0814	amino acid
GII82_16985	COG2197	response regulator
GII82_16990	COG4585	Histidine kinase
GII82_16995	COG4758	membrane
GII82_17000	COG3595	metallopeptidase activity
GII82_17005	COG1842	Phage shock protein A
GII82_17010	COG4758	membrane
GII82_17015	COG2814	Major facilitator Superfamily
GII82_17020	COG2096	Adenosyltransferase
GII82_17025	COG1120	ATPase activity
GII82_17030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII82_17035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII82_17040	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_17045	COG3386	PFAM SMP-30 Gluconolaconase
GII82_17050	COG2205	protein histidine kinase activity
GII82_17055	COG0745	RESPONSE REGULATOR receiver
GII82_17065	COG1191	sigma factor activity
GII82_17075	COG2140	Oxalate decarboxylase
GII82_17085	COG0577	efflux transmembrane transporter activity
GII82_17090	COG1136	(ABC) transporter
GII82_17095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII82_17100	COG1120	ATPase activity
GII82_17105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII82_17110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII82_17115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII82_17120	COG0531	amino acid
GII82_17130	COG1988	membrane-bound metal-dependent
GII82_17135	COG1368	sulfuric ester hydrolase activity
GII82_17140	COG1910	domain protein
GII82_17145	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII82_17150	COG4149	molybdate abc transporter
GII82_17155	COG0656	L-ascorbic acid biosynthetic process
GII82_17165	COG0025	NhaP-type Na H and K H
GII82_17170	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII82_17175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII82_17180	COG3973	AAA domain
GII82_17190	COG2860	membrane
GII82_17195	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII82_17200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII82_17205	COG2217	Heavy metal translocating P-type atpase
GII82_17210	COG2217	Heavy metal translocating P-type atpase
GII82_17215	COG2608	mercury ion transmembrane transporter activity
GII82_17220	COG1937	Protein conserved in bacteria
GII82_17225	COG0673	inositol 2-dehydrogenase activity
GII82_17230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII82_17235	COG1289	transmembrane transporter activity
GII82_17245	COG2076	Multidrug Resistance protein
GII82_17250	COG1309	transcriptional regulator
GII82_17255	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_17265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII82_17270	COG0557	exoribonuclease II activity
GII82_17275	COG1647	Serine aminopeptidase, S33
GII82_17280	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII82_17285	COG0596	Alpha beta hydrolase
GII82_17290	COG1476	TRANSCRIPTIONal
GII82_17295	COG1396	sequence-specific DNA binding
GII82_17300	COG1396	sequence-specific DNA binding
GII82_17305	COG1733	regulation of RNA biosynthetic process
GII82_17310	COG0840	transmembrane signaling receptor activity
GII82_17315	COG1174	glycine betaine transport
GII82_17320	COG1732	Glycine betaine
GII82_17325	COG1174	glycine betaine transport
GII82_17330	COG1125	glycine betaine transport
GII82_17330	COG0517	IMP dehydrogenase activity
GII82_17335	COG1510	regulation of RNA biosynthetic process
GII82_17340	COG1174	glycine betaine transport
GII82_17345	COG1732	Glycine betaine
GII82_17350	COG1174	glycine betaine transport
GII82_17355	COG1125	glycine betaine transport
GII82_17355	COG0517	IMP dehydrogenase activity
GII82_17360	COG1510	regulation of RNA biosynthetic process
GII82_17365	COG2095	MarC family integral membrane protein
GII82_17375	COG3064	Membrane
GII82_17380	COG4640	response to antibiotic
GII82_17385	COG0456	acetyltransferase
GII82_17390	COG0148	phosphopyruvate hydratase activity
GII82_17395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII82_17400	COG0149	triose-phosphate isomerase activity
GII82_17405	COG0126	phosphoglycerate kinase activity
GII82_17410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII82_17415	COG2390	Transcriptional regulator
GII82_17420	COG2814	Major facilitator Superfamily
GII82_17425	COG1609	Transcriptional regulator
GII82_17430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII82_17440	COG0583	DNA-binding transcription factor activity
GII82_17445	COG0697	spore germination
GII82_17450	COG1113	amino acid transport
GII82_17455	COG3858	chitin binding
GII82_17460	COG1556	Lactate utilization protein
GII82_17465	COG1139	Iron-sulfur cluster binding protein
GII82_17470	COG0247	lactate metabolic process
GII82_17475	COG2197	response regulator
GII82_17480	COG4585	Histidine kinase
GII82_17485	COG0842	Transport permease protein
GII82_17490	COG1131	(ABC) transporter
GII82_17495	COG0596	Alpha beta hydrolase
GII82_17500	COG2208	phosphoserine phosphatase activity
GII82_17505	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII82_17510	COG1874	Beta-galactosidase
GII82_17515	COG3833	ABC-type maltose transport systems, permease component
GII82_17520	COG1175	transmembrane transport
GII82_17525	COG2182	Extracellular solute-binding protein
GII82_17530	COG1609	Transcriptional regulator
GII82_17535	COG2186	Transcriptional regulator
GII82_17540	COG1620	l-lactate permease
GII82_17545	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII82_17555	COG5039	Polysaccharide pyruvyl transferase
GII82_17560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII82_17565	COG0110	maltose O-acetyltransferase activity
GII82_17570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII82_17575	COG2244	polysaccharide biosynthetic process
GII82_17580	COG1216	Glycosyl transferase, family 2
GII82_17585	COG5039	Polysaccharide pyruvyl transferase
GII82_17590	COG1216	Glycosyl transferase, family 2
GII82_17600	COG0438	transferase activity, transferring glycosyl groups
GII82_17605	COG1215	transferase activity, transferring glycosyl groups
GII82_17610	COG0438	transferase activity, transferring glycosyl groups
GII82_17615	COG1086	Polysaccharide biosynthesis protein
GII82_17620	COG0489	protein tyrosine kinase activity
GII82_17625	COG3944	biosynthesis protein
GII82_17630	COG1396	sequence-specific DNA binding
GII82_17635	COG2272	Belongs to the type-B carboxylesterase lipase family
GII82_17645	COG3479	Phenolic acid decarboxylase
GII82_17655	COG1794	racemase activity, acting on amino acids and derivatives
GII82_17660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII82_17665	COG1621	beta-fructofuranosidase activity
GII82_17670	COG1621	beta-fructofuranosidase activity
GII82_17675	COG0531	amino acid
GII82_17680	COG1309	transcriptional regulator
GII82_17685	COG2076	Multidrug Resistance protein
GII82_17690	COG2076	Multidrug Resistance protein
GII82_17700	COG0277	FAD linked oxidase domain protein
GII82_17705	COG3621	Patatin-like phospholipase
GII82_17715	COG0740	serine-type endopeptidase activity
GII82_17720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII82_17725	COG0366	Alpha amylase catalytic
GII82_17730	COG1554	hydrolase, family 65, central catalytic
GII82_17735	COG5521	maltodextrose utilization protein MalA
GII82_17740	COG3833	ABC-type maltose transport systems, permease component
GII82_17745	COG1175	transmembrane transport
GII82_17750	COG2182	Extracellular solute-binding protein
GII82_17755	COG0366	Alpha amylase catalytic
GII82_17760	COG1609	Transcriptional regulator
GII82_17765	COG1611	Belongs to the LOG family
GII82_17770	COG1694	Mazg nucleotide pyrophosphohydrolase
GII82_17775	COG0659	secondary active sulfate transmembrane transporter activity
GII82_17780	COG0288	reversible hydration of carbon dioxide
GII82_17785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII82_17790	COG0577	efflux transmembrane transporter activity
GII82_17795	COG1136	(ABC) transporter
GII82_17800	COG5002	protein histidine kinase activity
GII82_17805	COG0745	RESPONSE REGULATOR receiver
GII82_17815	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII82_17820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII82_17825	COG1481	regulation of sporulation
GII82_17830	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII82_17835	COG1660	Displays ATPase and GTPase activities
GII82_17840	COG1051	belongs to the nudix hydrolase family
GII82_17845	COG0492	ferredoxin-NADP+ reductase activity
GII82_17850	COG3883	PFAM NLP P60 protein
GII82_17850	COG0791	NLP P60 protein
GII82_17855	COG0457	Tetratricopeptide repeat
GII82_17860	COG1132	(ABC) transporter
GII82_17880	COG0140	phosphoribosyl-ATP diphosphatase activity
GII82_17880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII82_17885	COG0107	imidazoleglycerol-phosphate synthase activity
GII82_17890	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII82_17895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII82_17900	COG0131	Imidazoleglycerol-phosphate dehydratase
GII82_17905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII82_17910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII82_17915	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII82_17920	COG4990	cell redox homeostasis
GII82_17925	COG5297	Belongs to the glycosyl hydrolase family 6
GII82_17930	COG0110	maltose O-acetyltransferase activity
GII82_17935	COG0546	phosphoglycolate phosphatase activity
GII82_17940	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII82_17945	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII82_17950	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII82_17955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII82_17960	COG0363	glucosamine-6-phosphate deaminase activity
GII82_17970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII82_17975	COG1846	Transcriptional regulator
GII82_17980	COG2124	cytochrome p450
GII82_17990	COG1846	Transcriptional regulator
GII82_17995	COG2814	Major facilitator Superfamily
GII82_18000	COG1950	PFAM Membrane protein of
GII82_18005	COG1983	PspC domain protein
GII82_18010	COG3595	metallopeptidase activity
GII82_18025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII82_18030	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII82_18035	COG0556	nucleotide-excision repair
GII82_18040	COG4897	Protein conserved in bacteria
GII82_18045	COG3848	Pyruvate phosphate dikinase
GII82_18045	COG0574	Belongs to the PEP-utilizing enzyme family
GII82_18050	COG1309	transcriptional regulator
GII82_18055	COG2814	Major facilitator Superfamily
GII82_18060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII82_18070	COG0793	Belongs to the peptidase S41A family
GII82_18070	COG3409	Peptidoglycan-binding domain 1 protein
GII82_18075	COG2177	Part of the ABC transporter FtsEX involved in
GII82_18080	COG2884	Cell division ATP-binding protein ftsE
GII82_18085	COG2010	Cytochrome c
GII82_18090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII82_18100	COG0653	protein targeting
GII82_18105	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII82_18120	COG1516	flagellar protein fliS
GII82_18125	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII82_18130	COG1334	flagellar protein FlaG
GII82_18135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII82_18140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII82_18145	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII82_18155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII82_18160	COG1256	bacterial-type flagellum assembly
GII82_18160	COG4786	Flagellar basal body rod
GII82_18165	COG3418	PFAM FlgN family protein
GII82_18170	COG2747	anti-sigma28 factor FlgM
GII82_18180	COG1040	competence protein
GII82_18190	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII82_18195	COG1307	EDD domain protein, DegV family
GII82_18200	COG2197	response regulator
GII82_18205	COG4585	Histidine kinase
GII82_18210	COG1739	Uncharacterized protein family UPF0029
GII82_18215	COG1316	TRANSCRIPTIONal
GII82_18220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII82_18225	COG0438	transferase activity, transferring glycosyl groups
GII82_18230	COG1215	transferase activity, transferring glycosyl groups
GII82_18235	COG3206	protein involved in exopolysaccharide biosynthesis
GII82_18240	COG3307	-O-antigen
GII82_18245	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII82_18250	COG0297	glycogen (starch) synthase activity
GII82_18250	COG0438	transferase activity, transferring glycosyl groups
GII82_18255	COG2244	polysaccharide biosynthetic process
GII82_18270	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII82_18270	COG2247	cell wall binding repeat
GII82_18275	COG2385	sporulation resulting in formation of a cellular spore
GII82_18275	COG2247	cell wall binding repeat
GII82_18285	COG1316	TRANSCRIPTIONal
GII82_18290	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII82_18310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII82_18315	COG1134	teichoic acid transport
GII82_18320	COG1682	transport, permease protein
GII82_18335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII82_18335	COG1215	transferase activity, transferring glycosyl groups
GII82_18340	COG0463	Glycosyl transferase, family 2
GII82_18385	COG4193	domain, Protein
GII82_18390	COG1482	cell wall glycoprotein biosynthetic process
GII82_18395	COG0697	spore germination
GII82_18400	COG0814	amino acid
GII82_18410	COG2814	Major facilitator Superfamily
GII82_18415	COG1316	TRANSCRIPTIONal
GII82_18420	COG0561	phosphatase activity
GII82_18425	COG0791	NLP P60 protein
GII82_18435	COG2843	Capsule synthesis protein
GII82_18445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII82_18450	COG1609	Transcriptional regulator
GII82_18455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII82_18460	COG1869	D-ribose catabolic process
GII82_18465	COG1129	ABC transporter
GII82_18470	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII82_18475	COG1879	ABC-type sugar transport system periplasmic component
GII82_18480	COG3103	Sh3 type 3 domain protein
GII82_18490	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII82_18495	COG3527	Alpha-acetolactate decarboxylase
GII82_18500	COG0028	Belongs to the TPP enzyme family
GII82_18505	COG0583	DNA-binding transcription factor activity
GII82_18510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII82_18525	COG5337	Spore coat protein CotH
GII82_18535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII82_18545	COG0405	Gamma-glutamyltransferase
GII82_18550	COG1522	sequence-specific DNA binding
GII82_18555	COG2059	Chromate
GII82_18560	COG2059	Chromate
GII82_18570	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII82_18575	COG0583	DNA-binding transcription factor activity
GII82_18605	COG5444	nuclease activity
GII82_18625	COG3878	Protein conserved in bacteria
GII82_18630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII82_18635	COG4464	protein tyrosine phosphatase activity
GII82_18640	COG0489	protein tyrosine kinase activity
GII82_18645	COG3944	biosynthesis protein
GII82_18655	COG4715	Zinc finger, swim domain protein
GII82_18660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII82_18665	COG0561	phosphatase activity
GII82_18670	COG1349	DNA-binding transcription factor activity
GII82_18675	COG0629	single-stranded DNA binding
GII82_18690	COG3764	Sortase (surface protein transpeptidase)
GII82_18695	COG0745	RESPONSE REGULATOR receiver
GII82_18695	COG2972	Histidine kinase
GII82_18700	COG1970	mechanosensitive ion channel activity
GII82_18705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII82_18710	COG0457	Tetratricopeptide repeat
GII82_18715	COG4786	Flagellar basal body rod
GII82_18720	COG4786	Flagellar basal body rod
GII82_18725	COG1077	Cell shape determining protein MreB Mrl
GII82_18730	COG1609	Transcriptional regulator
GII82_18740	COG1846	Transcriptional regulator
GII82_18745	COG2814	Major facilitator Superfamily
GII82_18750	COG3420	alginic acid biosynthetic process
GII82_18755	COG1953	Uracil, thiamine, allantoin
GII82_18760	COG0477	Major facilitator Superfamily
GII82_18765	COG1335	isochorismatase
GII82_18775	COG0004	ammonium transporteR
GII82_18780	COG0347	Belongs to the P(II) protein family
GII82_18785	COG0671	phosphoesterase, PA-phosphatase related
GII82_18795	COG0739	heme binding
GII82_18800	COG1247	-acetyltransferase
GII82_18820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII82_18825	COG0789	Transcriptional regulator
GII82_18835	COG2910	NAD(P)H-binding
GII82_18840	COG1959	2 iron, 2 sulfur cluster binding
GII82_18845	COG0804	urea catabolic process
GII82_18850	COG0832	Belongs to the urease beta subunit family
GII82_18855	COG0831	urea catabolic process
GII82_18870	COG3237	CsbD-like
GII82_18875	COG1994	Peptidase M50
GII82_18880	COG0457	Tetratricopeptide repeat
GII82_18885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII82_18890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII82_18900	COG2304	oxidoreductase activity
GII82_18910	COG2304	oxidoreductase activity
GII82_18915	COG2385	sporulation resulting in formation of a cellular spore
GII82_18920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII82_18930	COG4836	Membrane
GII82_18940	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII82_18945	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII82_18950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII82_18955	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII82_18960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII82_18965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII82_18970	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII82_18975	COG0356	it plays a direct role in the translocation of protons across the membrane
GII82_18985	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII82_18990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII82_18995	COG4475	Protein of unknown function (DUF436)
GII82_19000	COG0698	ribose 5-phosphate isomerase
GII82_19005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII82_19010	COG1971	Probably functions as a manganese efflux pump
GII82_19015	COG0009	L-threonylcarbamoyladenylate synthase
GII82_19020	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII82_19040	COG2890	protein-(glutamine-N5) methyltransferase activity
GII82_19045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII82_19050	COG0346	lactoylglutathione lyase activity
GII82_19055	COG0789	Transcriptional regulator
GII82_19060	COG0679	Auxin Efflux Carrier
GII82_19065	COG0281	malic enzyme
GII82_19070	COG1435	thymidine kinase activity
GII82_19075	COG0254	rRNA binding
GII82_19080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII82_19090	COG1494	fructose-1,6-bisphosphatase
GII82_19095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII82_19100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII82_19105	COG0191	fructose-bisphosphate aldolase activity
GII82_19110	COG2204	response regulator
GII82_19115	COG4821	SIS domain
GII82_19120	COG0504	CTP synthase activity
GII82_19125	COG3343	RNA polymerase activity
GII82_19130	COG1960	acyl-CoA dehydrogenase activity
GII82_19135	COG0247	lactate metabolic process
GII82_19135	COG2181	nitrate reductase activity
GII82_19140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII82_19145	COG4294	response to UV
GII82_19155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII82_19160	COG1132	(ABC) transporter
GII82_19165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII82_19175	COG2181	nitrate reductase activity
GII82_19180	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GII82_19185	COG1140	nitrate reductase beta subunit
GII82_19190	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII82_19195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII82_19205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII82_19210	COG2223	nitrite transmembrane transporter activity
GII82_19215	COG0018	arginyl-trna synthetase
GII82_19220	COG4506	Protein conserved in bacteria
GII82_19235	COG0535	radical SAM domain protein
GII82_19245	COG1131	(ABC) transporter
GII82_19250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII82_19255	COG0612	Peptidase, M16
GII82_19260	COG0612	Peptidase, M16
GII82_19270	COG3391	amine dehydrogenase activity
GII82_19275	COG3391	amine dehydrogenase activity
GII82_19285	COG0457	Tetratricopeptide repeat
GII82_19315	COG1131	(ABC) transporter
GII82_19325	COG0010	Belongs to the arginase family
GII82_19330	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII82_19335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII82_19345	COG1994	Peptidase M50
GII82_19350	COG1942	4-Oxalocrotonate Tautomerase
GII82_19355	COG1846	Transcriptional regulator
GII82_19360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII82_19365	COG0477	Major facilitator Superfamily
GII82_19370	COG1959	2 iron, 2 sulfur cluster binding
GII82_19375	COG3465	dGTPase activity
GII82_19380	COG1078	dGTPase activity
GII82_19385	COG4844	belongs to the
GII82_19395	COG0697	spore germination
GII82_19400	COG0095	Lipoate-protein ligase
GII82_19405	COG0583	DNA-binding transcription factor activity
GII82_19410	COG0280	phosphate acetyltransferase
GII82_19420	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_19425	COG0436	Aminotransferase
GII82_19430	COG2814	Major facilitator Superfamily
GII82_19435	COG0151	Belongs to the GarS family
GII82_19440	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_19445	COG1917	Cupin 2, conserved barrel domain protein
GII82_19450	COG0077	Prephenate dehydratase
GII82_19455	COG2814	Major facilitator Superfamily
GII82_19460	COG0833	amino acid
GII82_19465	COG4187	Peptidase family M20/M25/M40
GII82_19470	COG1012	belongs to the aldehyde dehydrogenase family
GII82_19475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII82_19485	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII82_19490	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII82_19495	COG1088	dTDP-glucose 4,6-dehydratase activity
GII82_19500	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII82_19505	COG3980	spore coat polysaccharide biosynthesis protein
GII82_19510	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII82_19515	COG2089	acid synthase
GII82_19520	COG0456	acetyltransferase
GII82_19525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII82_19530	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII82_19535	COG0463	Glycosyl transferase, family 2
GII82_19545	COG2363	Small membrane protein
GII82_19550	COG2233	PERMEase
GII82_19560	COG1012	belongs to the aldehyde dehydrogenase family
GII82_19565	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII82_19570	COG1216	Glycosyl transferase, family 2
GII82_19575	COG0351	phosphomethylpyrimidine kinase
GII82_19585	COG1621	beta-fructofuranosidase activity
GII82_19590	COG1263	PTS System
GII82_19590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII82_19595	COG2116	formate transmembrane transporter activity
GII82_19600	COG3711	transcriptional antiterminator
GII82_19610	COG1404	Belongs to the peptidase S8 family
GII82_19615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII82_19620	COG0778	Nitroreductase
GII82_19625	COG0772	Belongs to the SEDS family
GII82_19635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII82_19640	COG1845	cytochrome c oxidase, subunit III
GII82_19645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII82_19650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII82_19655	COG2261	transglycosylase associated protein
GII82_19660	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII82_19665	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII82_19670	COG2246	polysaccharide biosynthetic process
GII82_19675	COG1309	transcriptional regulator
GII82_19685	COG3162	membrane
GII82_19690	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII82_19695	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII82_19700	COG2837	iron assimilation
GII82_19705	COG2822	iron ion transport
GII82_19710	COG0672	)-iron permease
GII82_19715	COG0352	thiamine-phosphate diphosphorylase activity
GII82_19720	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII82_19725	COG0583	DNA-binding transcription factor activity
GII82_19730	COG1380	Effector of murein hydrolase LrgA
GII82_19735	COG1346	cytolysis
GII82_19740	COG2814	Major facilitator Superfamily
GII82_19745	COG4895	conserved protein (DUF2196)
GII82_19750	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII82_19755	COG0346	lactoylglutathione lyase activity
GII82_19760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII82_19765	COG1404	Belongs to the peptidase S8 family
GII82_19770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII82_19770	COG1263	PTS System
GII82_19775	COG3711	transcriptional antiterminator
GII82_19780	COG1442	glycosyl transferase family 8
GII82_19785	COG5522	Integral membrane protein (intg_mem_TP0381)
GII82_19790	COG1846	Transcriptional regulator
GII82_19795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII82_19800	COG2234	aminopeptidase activity
GII82_19820	COG2357	RelA SpoT domain protein
GII82_19825	COG1575	Belongs to the MenA family. Type 1 subfamily
GII82_19840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII82_19845	COG1696	Membrane protein involved in D-alanine export
GII82_19850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII82_19855	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII82_19860	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII82_19865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII82_19870	COG1486	melibiose metabolic process
GII82_19875	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII82_19880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII82_19885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII82_19890	COG3711	transcriptional antiterminator
GII82_19890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII82_19900	COG2094	Belongs to the DNA glycosylase MPG family
GII82_19905	COG0753	catalase activity
GII82_19915	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII82_19920	COG1131	(ABC) transporter
GII82_19940	COG1595	DNA-templated transcription, initiation
GII82_19945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII82_19950	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII82_19955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII82_19960	COG4988	ABC transporter
GII82_19965	COG1294	oxidase, subunit
GII82_19970	COG1271	oxidase subunit
GII82_19975	COG3493	citrate carrier protein
GII82_19980	COG0501	Belongs to the peptidase M48B family
GII82_19990	COG0726	polysaccharide deacetylase
GII82_19995	COG3842	ATPase activity
GII82_20000	COG2508	Transcriptional regulator
GII82_20005	COG1012	belongs to the aldehyde dehydrogenase family
GII82_20010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII82_20020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII82_20025	COG1881	PFAM PEBP family protein
GII82_20030	COG0583	DNA-binding transcription factor activity
GII82_20040	COG4585	Histidine kinase
GII82_20045	COG2197	response regulator
GII82_20050	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII82_20060	COG4894	glucomannan catabolic process
GII82_20065	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII82_20070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII82_20075	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_20080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII82_20085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII82_20090	COG2610	gluconate transmembrane transporter activity
GII82_20095	COG0500	methyltransferase
GII82_20100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII82_20115	COG0693	protein deglycase activity
GII82_20115	COG0753	catalase activity
GII82_20120	COG2851	Citrate transporter
GII82_20125	COG2273	Hydrolase Family 16
GII82_20130	COG3711	transcriptional antiterminator
GII82_20140	COG2270	Major facilitator Superfamily
GII82_20145	COG0513	Belongs to the DEAD box helicase family
GII82_20150	COG3401	FG-GAP repeat protein
GII82_20150	COG2755	lipolytic protein G-D-S-L family
GII82_20180	COG0697	spore germination
GII82_20185	COG0589	response to stress
GII82_20190	COG2723	6-phospho-beta-galactosidase activity
GII82_20195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII82_20195	COG1263	PTS System
GII82_20195	COG2190	(PTS) system
GII82_20210	COG5444	nuclease activity
GII82_20225	COG3507	Belongs to the glycosyl hydrolase 43 family
GII82_20240	COG2986	histidine ammonia-lyase
GII82_20245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII82_20250	COG1228	amidohydrolase
GII82_20255	COG0010	Belongs to the arginase family
GII82_20260	COG0833	amino acid
GII82_20265	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII82_20270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII82_20275	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII82_20280	COG2390	Transcriptional regulator
GII82_20290	COG3192	ethanolamine utilization protein
GII82_20295	COG2079	MmgE PrpD family protein
GII82_20305	COG1126	abc transporter atp-binding protein
GII82_20310	COG0765	amino acid transport
GII82_20315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII82_20335	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII82_20340	COG0561	phosphatase activity
GII82_20370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII82_20375	COG5294	Protein conserved in bacteria
GII82_20380	COG0577	efflux transmembrane transporter activity
GII82_20385	COG1136	(ABC) transporter
GII82_20390	COG2205	protein histidine kinase activity
GII82_20395	COG0745	RESPONSE REGULATOR receiver
GII82_20400	COG0191	fructose-bisphosphate aldolase activity
GII82_20405	COG1082	Xylose isomerase domain protein TIM barrel
GII82_20410	COG1082	Xylose isomerase domain protein TIM barrel
GII82_20415	COG0673	inositol 2-dehydrogenase activity
GII82_20420	COG2814	Major facilitator Superfamily
GII82_20425	COG1082	Xylose isomerase domain protein TIM barrel
GII82_20430	COG3962	Belongs to the TPP enzyme family
GII82_20435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII82_20445	COG1012	belongs to the aldehyde dehydrogenase family
GII82_20450	COG1349	DNA-binding transcription factor activity
GII82_20455	COG0667	Aldo Keto reductase
GII82_20470	COG2814	Major facilitator Superfamily
GII82_20475	COG0326	Molecular chaperone. Has ATPase activity
GII82_20485	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_20490	COG1309	transcriptional regulator
GII82_20495	COG1012	belongs to the aldehyde dehydrogenase family
GII82_20500	COG1714	RDD family
GII82_20505	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GII82_20515	COG1714	RDD family
GII82_20520	COG2311	Membrane
GII82_20525	COG1917	Cupin 2, conserved barrel domain protein
GII82_20530	COG1309	transcriptional regulator
GII82_20535	COG1028	Short-chain dehydrogenase reductase Sdr
GII82_20540	COG1846	Transcriptional regulator
GII82_20545	COG1380	Effector of murein hydrolase LrgA
GII82_20550	COG1346	cytolysis
GII82_20555	COG5039	Polysaccharide pyruvyl transferase
GII82_20560	COG1929	Belongs to the glycerate kinase type-1 family
GII82_20565	COG1802	Transcriptional regulator
GII82_20570	COG1070	Carbohydrate kinase
GII82_20575	COG2610	gluconate transmembrane transporter activity
GII82_20580	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII82_20585	COG0450	alkyl hydroperoxide reductase
GII82_20590	COG3634	alkyl hydroperoxide reductase activity
GII82_20600	COG2723	6-phospho-beta-galactosidase activity
GII82_20605	COG2190	(PTS) system
GII82_20610	COG2188	Transcriptional regulator
GII82_20620	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII82_20655	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII82_20670	COG1063	alcohol dehydrogenase
GII82_20690	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII82_20695	COG0456	acetyltransferase
GII82_20700	COG0457	Tetratricopeptide repeat
GII82_20710	COG0010	Belongs to the arginase family
GII82_20715	COG0833	amino acid
GII82_20720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII82_20725	COG3829	transcription factor binding
GII82_20730	COG5002	protein histidine kinase activity
GII82_20755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII82_20760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII82_20765	COG4853	Protein conserved in bacteria
GII82_20770	COG4863	YycH protein
GII82_20775	COG5002	protein histidine kinase activity
GII82_20780	COG0745	RESPONSE REGULATOR receiver
GII82_20810	COG0346	lactoylglutathione lyase activity
GII82_20815	COG0305	Participates in initiation and elongation during chromosome replication
GII82_20830	COG3093	addiction module antidote protein HigA
GII82_20835	COG2807	transmembrane transport
GII82_20840	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII82_20845	COG0359	binds to the 23S rRNA
GII82_20850	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII82_20855	COG4241	membrane
GII82_20865	COG5577	PFAM Coat F domain
GII82_20870	COG1733	regulation of RNA biosynthetic process
GII82_20875	COG1227	inorganic diphosphatase activity
GII82_20885	COG2271	Major facilitator Superfamily
GII82_20890	COG0789	Transcriptional regulator
GII82_20890	COG4978	Transcriptional regulator
GII82_20900	COG4319	ketosteroid isomerase
GII82_20905	COG1357	PFAM Pentapeptide repeats (8 copies)
GII82_20910	COG2814	Major facilitator Superfamily
GII82_20915	COG0583	DNA-binding transcription factor activity
GII82_20920	COG2153	protein acetylation
GII82_20930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII82_20935	COG1846	Transcriptional regulator
GII82_20940	COG2153	protein acetylation
GII82_20945	COG2364	Membrane
GII82_20950	COG0456	acetyltransferase
GII82_20955	COG2315	Protein conserved in bacteria
GII82_20960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII82_20970	COG2814	Major facilitator Superfamily
GII82_20980	COG1331	Highly conserved protein containing a thioredoxin domain
GII82_20995	COG0789	Transcriptional regulator
GII82_21000	COG0697	spore germination
GII82_21010	COG1280	lysine exporter protein (LysE YggA)
GII82_21015	COG1331	Highly conserved protein containing a thioredoxin domain
GII82_21020	COG1331	Highly conserved protein containing a thioredoxin domain
GII82_21025	COG1266	CAAX protease self-immunity
GII82_21030	COG2814	Major facilitator Superfamily
GII82_21030	COG0477	Major facilitator Superfamily
GII82_21035	COG0110	maltose O-acetyltransferase activity
GII82_21040	COG0346	lactoylglutathione lyase activity
GII82_21045	COG1609	Transcriptional regulator
GII82_21050	COG0708	Exodeoxyribonuclease III
GII82_21055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII82_21060	COG0629	single-stranded DNA binding
GII82_21065	COG0360	Binds together with S18 to 16S ribosomal RNA
GII82_21070	COG0012	GTP binding
GII82_21075	COG0243	molybdopterin cofactor binding
GII82_21080	COG4481	Protein conserved in bacteria
GII82_21085	COG3949	Membrane
GII82_21095	COG1475	DNA binding
GII82_21100	COG1192	Involved in chromosome partitioning
GII82_21110	COG1475	DNA binding
GII82_21115	COG0357	Ribosomal RNA small subunit methyltransferase G
GII82_21120	COG0445	tRNA wobble uridine modification
GII82_21125	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII82_21130	COG1847	R3H domain protein
GII82_21135	COG0706	membrane insertase activity
GII82_21140	COG0594	ribonuclease P activity
GII82_21145	COG0230	Belongs to the bacterial ribosomal protein bL34 family