locus-tag	class	description
GII83_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII83_00010	COG0592	DNA-directed DNA polymerase activity
GII83_00015	COG2501	S4 domain
GII83_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII83_00030	COG0187	DNA topoisomerase II activity
GII83_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII83_00070	COG0517	IMP dehydrogenase activity
GII83_00070	COG0516	GMP reductase activity
GII83_00075	COG1686	Belongs to the peptidase S11 family
GII83_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII83_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII83_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII83_00100	COG1428	Deoxynucleoside kinase
GII83_00105	COG1428	Deoxynucleoside kinase
GII83_00110	COG3858	chitin binding
GII83_00110	COG1388	LysM domain
GII83_00115	COG1335	isochorismatase
GII83_00120	COG0590	tRNA wobble adenosine to inosine editing
GII83_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII83_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII83_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII83_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII83_00190	COG3853	Toxic anion resistance protein (TelA)
GII83_00195	COG1982	Orn Lys Arg decarboxylase major
GII83_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII83_00205	COG3870	Protein conserved in bacteria
GII83_00210	COG1728	Protein conserved in bacteria
GII83_00215	COG0470	DNA polymerase III
GII83_00220	COG1774	PSP1 C-terminal conserved region
GII83_00225	COG4467	Involved in initiation control of chromosome replication
GII83_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII83_00235	COG2827	Endonuclease containing a URI domain
GII83_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII83_00245	COG2002	toxin-antitoxin pair type II binding
GII83_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII83_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII83_00255	COG0084	hydrolase, TatD family'
GII83_00260	COG3583	domain protein
GII83_00260	COG3584	3D domain protein
GII83_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII83_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII83_00280	COG4466	Protein conserved in bacteria
GII83_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII83_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII83_00300	COG0251	oxidation-reduction process
GII83_00305	COG2088	sporulation resulting in formation of a cellular spore
GII83_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII83_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII83_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII83_00325	COG0193	aminoacyl-tRNA hydrolase activity
GII83_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII83_00340	COG2002	toxin-antitoxin pair type II binding
GII83_00345	COG2244	polysaccharide biosynthetic process
GII83_00350	COG3956	TIGRFAM MazG family protein
GII83_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII83_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII83_00375	COG1098	S1 RNA binding domain
GII83_00390	COG2208	phosphoserine phosphatase activity
GII83_00395	COG2304	oxidoreductase activity
GII83_00400	COG0515	serine threonine protein kinase
GII83_00405	COG0037	tRNA processing
GII83_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII83_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII83_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII83_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII83_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII83_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII83_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII83_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII83_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII83_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII83_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII83_00470	COG1396	sequence-specific DNA binding
GII83_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII83_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII83_00560	COG4463	regulation of RNA biosynthetic process
GII83_00565	COG3880	PFAM UvrB UvrC protein
GII83_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII83_00575	COG0542	response to heat
GII83_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII83_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII83_00590	COG4956	integral membrane protein (PIN domain superfamily)
GII83_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII83_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII83_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII83_00610	COG1045	serine acetyltransferase
GII83_00615	COG0215	cysteine-tRNA ligase activity
GII83_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII83_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII83_00630	COG3688	RNA-binding protein containing a PIN domain
GII83_00635	COG1595	DNA-templated transcription, initiation
GII83_00640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII83_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII83_00650	COG0250	Participates in transcription elongation, termination and antitermination
GII83_00655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GII83_00660	COG0081	regulation of translation
GII83_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII83_00670	COG0222	ribosome binding
GII83_00675	COG2813	Specifically methylates the guanine in position
GII83_00680	COG0085	RNA polymerase activity
GII83_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII83_00690	COG1358	cellular component organization or biogenesis
GII83_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII83_00700	COG0049	tRNA binding
GII83_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII83_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII83_00715	COG0596	Alpha beta hydrolase
GII83_00720	COG0051	transcription antitermination factor activity, RNA binding
GII83_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII83_00730	COG0088	Forms part of the polypeptide exit tunnel
GII83_00735	COG0089	rRNA binding
GII83_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII83_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GII83_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GII83_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GII83_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII83_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
GII83_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII83_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII83_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII83_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII83_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII83_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII83_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII83_00815	COG1841	ribosomal large subunit assembly
GII83_00820	COG0200	Binds to the 23S rRNA
GII83_00825	COG0201	protein transport
GII83_00830	COG0563	adenylate kinase activity
GII83_00835	COG0024	Methionine aminopeptidase
GII83_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII83_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GII83_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII83_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII83_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII83_00865	COG0202	RNA polymerase activity
GII83_00870	COG0203	ribosomal protein L17
GII83_00875	COG1122	ATPase activity
GII83_00880	COG1122	ATPase activity
GII83_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII83_00890	COG0101	tRNA pseudouridine synthase activity
GII83_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII83_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII83_00905	COG2226	methyltransferase
GII83_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII83_00920	COG0489	protein tyrosine kinase activity
GII83_00930	COG2194	sulfuric ester hydrolase activity
GII83_00935	COG0726	polysaccharide deacetylase
GII83_01025	COG0385	Bile acid
GII83_01030	COG2819	hydrolase of the alpha beta superfamily
GII83_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII83_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII83_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII83_01050	COG2207	Transcriptional regulator
GII83_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII83_01055	COG3876	Protein conserved in bacteria
GII83_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
GII83_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII83_01070	COG1263	PTS System
GII83_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_01075	COG1737	Transcriptional regulator
GII83_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII83_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII83_01090	COG1683	Conserved Protein
GII83_01120	COG1595	DNA-templated transcription, initiation
GII83_01125	COG5662	AntiSigma factor
GII83_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII83_01135	COG4856	YbbR-like protein
GII83_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII83_01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII83_01160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII83_01165	COG2169	Transcriptional regulator
GII83_01170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII83_01175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII83_01180	COG3002	Belongs to the UPF0753 family
GII83_01185	COG0288	reversible hydration of carbon dioxide
GII83_01195	COG5609	conserved protein (DUF2294)
GII83_01200	COG0640	Transcriptional regulator
GII83_01205	COG2814	Major facilitator Superfamily
GII83_01220	COG1404	Belongs to the peptidase S8 family
GII83_01240	COG1132	(ABC) transporter
GII83_01245	COG0596	Alpha beta hydrolase
GII83_01250	COG0745	RESPONSE REGULATOR receiver
GII83_01255	COG0642	Histidine kinase
GII83_01265	COG0515	serine threonine protein kinase
GII83_01280	COG1113	amino acid transport
GII83_01295	COG2602	Beta-lactamase
GII83_01300	COG2124	cytochrome p450
GII83_01310	COG0531	amino acid
GII83_01315	COG0584	glycerophosphoryl diester phosphodiesterase
GII83_01320	COG2271	Major facilitator Superfamily
GII83_01330	COG0456	acetyltransferase
GII83_01330	COG1846	Transcriptional regulator
GII83_01335	COG2271	Major facilitator Superfamily
GII83_01345	COG3409	Peptidoglycan-binding domain 1 protein
GII83_01350	COG0697	spore germination
GII83_01355	COG1917	Cupin 2, conserved barrel domain protein
GII83_01355	COG2207	Transcriptional regulator
GII83_01360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII83_01365	COG3591	Belongs to the peptidase S1B family
GII83_01375	COG0596	Alpha beta hydrolase
GII83_01380	COG1183	phosphatidylcholine synthase activity
GII83_01385	COG0586	Pfam SNARE associated Golgi protein
GII83_01390	COG0688	phosphatidylethanolamine metabolic process
GII83_01400	COG2312	Erythromycin esterase
GII83_01410	COG1301	dicarboxylic acid transport
GII83_01415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_01415	COG2190	(PTS) system
GII83_01415	COG1263	PTS System
GII83_01420	COG0363	glucosamine-6-phosphate deaminase activity
GII83_01435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII83_01440	COG0833	amino acid
GII83_01445	COG2040	homocysteine
GII83_01455	COG1115	amino acid carrier protein
GII83_01460	COG2066	Belongs to the glutaminase family
GII83_01465	COG4191	Histidine kinase
GII83_01470	COG0784	Response regulator, receiver
GII83_01475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII83_01480	COG1012	belongs to the aldehyde dehydrogenase family
GII83_01485	COG2271	Major facilitator Superfamily
GII83_01490	COG4948	Mandelate Racemase Muconate Lactonizing
GII83_01495	COG2186	Transcriptional regulator
GII83_01500	COG2721	sulfolactate sulfo-lyase activity
GII83_01505	COG3173	Aminoglycoside phosphotransferase
GII83_01520	COG0745	RESPONSE REGULATOR receiver
GII83_01525	COG2205	protein histidine kinase activity
GII83_01530	COG1131	(ABC) transporter
GII83_01550	COG3773	Cell wall hydrolase
GII83_01555	COG2304	oxidoreductase activity
GII83_01565	COG3540	Alkaline phosphatase
GII83_01570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII83_01575	COG0805	protein transport
GII83_01580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII83_01585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII83_01590	COG0477	Major facilitator Superfamily
GII83_01595	COG1309	transcriptional regulator
GII83_01600	COG0252	asparaginase activity
GII83_01605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII83_01610	COG1714	RDD family
GII83_01615	COG1405	negative regulation of cell septum assembly
GII83_01615	COG3012	SEC-C Motif Domain Protein
GII83_01620	COG3290	protein histidine kinase activity
GII83_01625	COG3279	Response regulator of the LytR AlgR family
GII83_01630	COG4555	ABC transporter
GII83_01635	COG1668	transmembrane transport
GII83_01640	COG0667	Aldo Keto reductase
GII83_01655	COG1595	DNA-templated transcription, initiation
GII83_01660	COG1595	DNA-templated transcription, initiation
GII83_01665	COG1876	peptidase activity
GII83_01670	COG0457	Tetratricopeptide repeat
GII83_01675	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_01680	COG0366	Alpha amylase catalytic
GII83_01685	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII83_01690	COG1121	(ABC) transporter
GII83_01695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII83_01700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII83_01705	COG2310	stress, protein
GII83_01710	COG2310	stress, protein
GII83_01715	COG2310	stress, protein
GII83_01720	COG0861	Integral membrane protein TerC family
GII83_01730	COG3853	Toxic anion resistance protein (TelA)
GII83_01735	COG0477	Major facilitator Superfamily
GII83_01740	COG2814	Major facilitator Superfamily
GII83_01745	COG0640	Transcriptional regulator
GII83_01750	COG0517	IMP dehydrogenase activity
GII83_01750	COG4175	Glycine betaine
GII83_01755	COG4176	ABC-type proline glycine betaine transport system permease component
GII83_01760	COG2113	Glycine betaine
GII83_01765	COG1473	amidohydrolase
GII83_01770	COG1288	antiporter activity
GII83_01780	COG0366	Alpha amylase catalytic
GII83_01785	COG0039	L-malate dehydrogenase activity
GII83_01790	COG1620	l-lactate permease
GII83_01795	COG2814	Major facilitator Superfamily
GII83_01800	COG1846	Transcriptional regulator
GII83_01805	COG1280	lysine exporter protein (LysE YggA)
GII83_01810	COG3403	YqcI/YcgG family
GII83_01815	COG1113	amino acid transport
GII83_01820	COG3665	Urea carboxylase-associated protein
GII83_01825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII83_01830	COG1660	Displays ATPase and GTPase activities
GII83_01835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII83_01840	COG2226	methyltransferase
GII83_01845	COG0583	DNA-binding transcription factor activity
GII83_01850	COG3458	cephalosporin-C deacetylase activity
GII83_01855	COG3541	Predicted nucleotidyltransferase
GII83_01860	COG0506	proline dehydrogenase activity
GII83_01865	COG1012	belongs to the aldehyde dehydrogenase family
GII83_01870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII83_01875	COG2508	Transcriptional regulator
GII83_01880	COG3689	TIGRFAM TIGR03943 family protein
GII83_01885	COG0701	Predicted permease
GII83_01890	COG2267	carboxylic ester hydrolase activity
GII83_01895	COG0492	ferredoxin-NADP+ reductase activity
GII83_01900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII83_01900	COG1587	Uroporphyrinogen-III synthase
GII83_01905	COG2146	nitrite reductase [NAD(P)H] activity
GII83_01910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII83_01915	COG0243	molybdopterin cofactor binding
GII83_01920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII83_01925	COG2223	nitrite transmembrane transporter activity
GII83_01930	COG1469	GTP cyclohydrolase I activity
GII83_01935	COG1376	ErfK ybiS ycfS ynhG family protein
GII83_01945	COG0523	cobalamin synthesis protein
GII83_01950	COG0765	amino acid transport
GII83_01955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII83_01965	COG1714	RDD family
GII83_01975	COG2723	6-phospho-beta-galactosidase activity
GII83_01985	COG3209	COG3209 Rhs family protein
GII83_01990	COG0840	transmembrane signaling receptor activity
GII83_01990	COG3290	protein histidine kinase activity
GII83_01995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII83_02000	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII83_02005	COG1733	regulation of RNA biosynthetic process
GII83_02010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_02025	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII83_02030	COG2814	Major facilitator Superfamily
GII83_02040	COG0697	spore germination
GII83_02055	COG2364	Membrane
GII83_02060	COG1126	abc transporter atp-binding protein
GII83_02065	COG0765	amino acid transport
GII83_02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII83_02075	COG0583	DNA-binding transcription factor activity
GII83_02080	COG0163	prenyltransferase activity
GII83_02085	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII83_02100	COG0596	Alpha beta hydrolase
GII83_02105	COG3104	oligopeptide transport
GII83_02110	COG5434	Belongs to the glycosyl hydrolase 28 family
GII83_02120	COG0697	spore germination
GII83_02130	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII83_02135	COG1136	(ABC) transporter
GII83_02140	COG0577	efflux transmembrane transporter activity
GII83_02145	COG0745	RESPONSE REGULATOR receiver
GII83_02150	COG3850	Histidine kinase
GII83_02150	COG5002	protein histidine kinase activity
GII83_02155	COG0457	Tetratricopeptide repeat
GII83_02175	COG0527	aspartate kinase activity
GII83_02180	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII83_02185	COG4605	iron ion homeostasis
GII83_02190	COG4604	ABC transporter, ATP-binding protein
GII83_02195	COG4607	ABC-type enterochelin transport system periplasmic component
GII83_02200	COG2814	Major facilitator Superfamily
GII83_02205	COG1309	transcriptional regulator
GII83_02210	COG0778	Nitroreductase
GII83_02215	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII83_02220	COG0640	Transcriptional regulator
GII83_02225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII83_02230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII83_02235	COG1012	belongs to the aldehyde dehydrogenase family
GII83_02240	COG4975	Glucose uptake
GII83_02245	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_02250	COG4549	nuclear export factor GLE1
GII83_02255	COG2372	response to copper ion
GII83_02255	COG1276	copper resistance
GII83_02260	COG1349	DNA-binding transcription factor activity
GII83_02270	COG2213	PTS system mannitol-specific
GII83_02275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII83_02280	COG0246	Mannitol dehydrogenase
GII83_02285	COG0473	3-isopropylmalate dehydrogenase activity
GII83_02290	COG0681	Belongs to the peptidase S26 family
GII83_02295	COG0412	Dienelactone hydrolase
GII83_02300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII83_02310	COG0561	phosphatase activity
GII83_02315	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII83_02320	COG1914	H( )-stimulated, divalent metal cation uptake system
GII83_02325	COG4336	lyase activity
GII83_02330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII83_02335	COG1984	allophanate hydrolase subunit 2
GII83_02340	COG1414	Transcriptional regulator
GII83_02345	COG2755	lipolytic protein G-D-S-L family
GII83_02355	COG2329	Antibiotic biosynthesis monooxygenase
GII83_02360	COG0768	penicillin binding
GII83_02365	COG4989	oxidoreductase activity
GII83_02370	COG3711	transcriptional antiterminator
GII83_02375	COG0318	PFAM AMP-dependent synthetase and ligase
GII83_02380	COG2226	methyltransferase
GII83_02385	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_02390	COG1917	Cupin 2, conserved barrel domain protein
GII83_02395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII83_02400	COG3871	stress protein (general stress protein 26)
GII83_02410	COG2814	Major facilitator Superfamily
GII83_02415	COG1522	sequence-specific DNA binding
GII83_02420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII83_02420	COG0551	DNA topoisomerase type I activity
GII83_02425	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII83_02430	COG3706	GGDEF domain
GII83_02435	COG5298	Protein conserved in bacteria
GII83_02440	COG1215	transferase activity, transferring glycosyl groups
GII83_02450	COG0531	amino acid
GII83_02455	COG0494	nUDIX hydrolase
GII83_02460	COG0028	Belongs to the TPP enzyme family
GII83_02475	COG1914	H( )-stimulated, divalent metal cation uptake system
GII83_02480	COG2261	transglycosylase associated protein
GII83_02485	COG4876	unkown
GII83_02490	COG2217	Heavy metal translocating P-type atpase
GII83_02495	COG3729	General stress protein
GII83_02500	COG0662	Cupin 2, conserved barrel domain protein
GII83_02505	COG2329	Antibiotic biosynthesis monooxygenase
GII83_02510	COG3546	catalase activity
GII83_02515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII83_02520	COG3290	protein histidine kinase activity
GII83_02525	COG4565	transcriptional regulatory protein
GII83_02530	COG1301	dicarboxylic acid transport
GII83_02535	COG0628	permease
GII83_02540	COG1131	(ABC) transporter
GII83_02545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII83_02555	COG1960	acyl-CoA dehydrogenase activity
GII83_02570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII83_02575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII83_02580	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII83_02585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII83_02590	COG0513	Belongs to the DEAD box helicase family
GII83_02595	COG3402	PFAM membrane-flanked domain
GII83_02600	COG3428	Bacterial PH domain
GII83_02605	COG0705	Rhomboid family
GII83_02610	COG0736	holo-[acyl-carrier-protein] synthase activity
GII83_02615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII83_02620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII83_02625	COG0864	Transcriptional regulator
GII83_02630	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII83_02635	COG1366	Belongs to the anti-sigma-factor antagonist family
GII83_02640	COG1366	Belongs to the anti-sigma-factor antagonist family
GII83_02645	COG2172	sigma factor antagonist activity
GII83_02650	COG2208	phosphoserine phosphatase activity
GII83_02655	COG1366	Belongs to the anti-sigma-factor antagonist family
GII83_02660	COG2172	sigma factor antagonist activity
GII83_02665	COG1191	sigma factor activity
GII83_02670	COG2208	phosphoserine phosphatase activity
GII83_02675	COG2183	response to ionizing radiation
GII83_02685	COG3091	SprT-like family
GII83_02725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII83_02770	COG1476	TRANSCRIPTIONal
GII83_02790	COG0693	protein deglycase activity
GII83_02795	COG1278	Cold shock
GII83_02800	COG1329	Transcriptional regulator
GII83_02805	COG0697	spore germination
GII83_02810	COG1917	Cupin 2, conserved barrel domain protein
GII83_02810	COG2207	Transcriptional regulator
GII83_02815	COG0697	spore germination
GII83_02820	COG3708	Transcriptional regulator
GII83_02820	COG2207	Transcriptional regulator
GII83_02825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII83_02830	COG0477	Major facilitator Superfamily
GII83_02840	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII83_02875	COG1309	transcriptional regulator
GII83_02880	COG0697	spore germination
GII83_02885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII83_02890	COG2030	dehydratase
GII83_02895	COG3545	Serine hydrolase
GII83_02900	COG1733	regulation of RNA biosynthetic process
GII83_02905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII83_02910	COG2814	Major facilitator Superfamily
GII83_02915	COG1309	transcriptional regulator
GII83_02925	COG0640	Transcriptional regulator
GII83_02930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII83_02940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII83_02945	COG0697	spore germination
GII83_02950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII83_02955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII83_02960	COG0640	Transcriptional regulator
GII83_02965	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII83_02980	COG4585	Histidine kinase
GII83_02985	COG2197	response regulator
GII83_02990	COG2409	Drug exporters of the RND superfamily
GII83_02995	COG0596	Alpha beta hydrolase
GII83_03000	COG1811	Na channel or pump
GII83_03005	COG0789	Transcriptional regulator
GII83_03005	COG4978	Transcriptional regulator
GII83_03010	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII83_03015	COG0778	Nitroreductase
GII83_03020	COG0346	lactoylglutathione lyase activity
GII83_03025	COG2259	Doxx family
GII83_03030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII83_03045	COG2323	membrane
GII83_03050	COG2323	membrane
GII83_03055	COG0071	Belongs to the small heat shock protein (HSP20) family
GII83_03070	COG1309	transcriptional regulator
GII83_03080	COG0456	acetyltransferase
GII83_03090	COG0673	inositol 2-dehydrogenase activity
GII83_03095	COG1609	Transcriptional regulator
GII83_03100	COG2814	Major facilitator Superfamily
GII83_03115	COG1113	amino acid transport
GII83_03120	COG2318	DinB family
GII83_03125	COG1846	Transcriptional regulator
GII83_03130	COG1033	growth of symbiont in host cell
GII83_03130	COG2409	Drug exporters of the RND superfamily
GII83_03135	COG0778	Nitroreductase
GII83_03140	COG1846	Transcriptional regulator
GII83_03145	COG2814	Major facilitator Superfamily
GII83_03150	COG0730	response to heat
GII83_03155	COG1802	Transcriptional regulator
GII83_03160	COG3858	chitin binding
GII83_03160	COG1388	LysM domain
GII83_03165	COG1819	glycosyl
GII83_03175	COG1785	Belongs to the alkaline phosphatase family
GII83_03180	COG5646	InterPro IPR014922
GII83_03190	COG0454	-acetyltransferase
GII83_03195	COG1078	dGTPase activity
GII83_03200	COG1388	LysM domain
GII83_03205	COG2814	Major facilitator Superfamily
GII83_03210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII83_03215	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII83_03220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII83_03225	COG2723	6-phospho-beta-galactosidase activity
GII83_03230	COG2188	Transcriptional regulator
GII83_03235	COG1940	carbohydrate kinase activity
GII83_03240	COG1482	cell wall glycoprotein biosynthetic process
GII83_03245	COG4124	Belongs to the glycosyl hydrolase 26 family
GII83_03290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII83_03295	COG0802	atpase or kinase
GII83_03300	COG1214	PFAM Peptidase M22, glycoprotease
GII83_03305	COG0456	acetyltransferase
GII83_03310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII83_03315	COG0488	(ABC) transporter
GII83_03320	COG0315	cyclic pyranopterin monophosphate synthase activity
GII83_03325	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII83_03330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII83_03335	COG0805	protein transport
GII83_03345	COG1266	CAAX protease self-immunity
GII83_03350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GII83_03355	COG0459	protein refolding
GII83_03365	COG1073	alpha beta
GII83_03370	COG0457	Tetratricopeptide repeat
GII83_03375	COG1063	alcohol dehydrogenase
GII83_03380	COG2211	Major facilitator Superfamily
GII83_03385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII83_03390	COG1842	Phage shock protein A
GII83_03395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII83_03400	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII83_03405	COG4260	virion core protein, lumpy skin disease virus
GII83_03415	COG2814	Major facilitator Superfamily
GII83_03420	COG1063	alcohol dehydrogenase
GII83_03425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII83_03430	COG0823	Involved in the tonB-independent uptake of proteins
GII83_03445	COG2267	carboxylic ester hydrolase activity
GII83_03455	COG2132	Multicopper oxidase
GII83_03460	COG1113	amino acid transport
GII83_03470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII83_03475	COG0714	Associated with various cellular activities
GII83_03480	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII83_03485	COG1305	Transglutaminase-like
GII83_03490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII83_03490	COG0519	Catalyzes the synthesis of GMP from XMP
GII83_03495	COG2252	PERMEase
GII83_03500	COG3064	Membrane
GII83_03510	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII83_03520	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII83_03525	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII83_03530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII83_03535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII83_03540	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII83_03545	COG0047	phosphoribosylformylglycinamidine synthase activity
GII83_03550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII83_03555	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII83_03560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII83_03565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII83_03570	COG0138	bifunctional purine biosynthesis protein purh
GII83_03575	COG0151	Belongs to the GarS family
GII83_03580	COG1522	sequence-specific DNA binding
GII83_03585	COG0531	amino acid
GII83_03595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII83_03600	COG1470	cell adhesion involved in biofilm formation
GII83_03605	COG4496	protein, YerC YecD
GII83_03610	COG0069	glutamate synthase activity
GII83_03615	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII83_03620	COG0210	DNA helicase
GII83_03625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII83_03630	COG4851	CamS sex pheromone cAM373 precursor
GII83_03635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII83_03640	COG1285	pathogenesis
GII83_03645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII83_03650	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII83_03655	COG0154	amidase activity
GII83_03660	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII83_03665	COG1309	transcriptional regulator
GII83_03670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII83_03675	COG1597	lipid kinase activity
GII83_03680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII83_03710	COG5444	nuclease activity
GII83_03720	COG3586	endonuclease activity
GII83_03730	COG0457	Tetratricopeptide repeat
GII83_03740	COG0217	transcriptional regulatory protein
GII83_03750	COG1309	transcriptional regulator
GII83_03755	COG3631	Ketosteroid isomerase-related protein
GII83_03760	COG0702	epimerase
GII83_03775	COG3546	catalase activity
GII83_03780	COG0454	-acetyltransferase
GII83_03790	COG5578	integral membrane protein
GII83_03795	COG2972	Histidine kinase
GII83_03800	COG4753	response regulator
GII83_03800	COG2207	Transcriptional regulator
GII83_03805	COG1653	transport
GII83_03810	COG1175	transmembrane transport
GII83_03815	COG0395	ABC-type sugar transport system, permease component
GII83_03820	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII83_03825	COG2207	Transcriptional regulator
GII83_03830	COG2755	lipolytic protein G-D-S-L family
GII83_03840	COG5578	integral membrane protein
GII83_03845	COG3401	FG-GAP repeat protein
GII83_03850	COG3401	FG-GAP repeat protein
GII83_03855	COG2755	lipolytic protein G-D-S-L family
GII83_03860	COG1874	Beta-galactosidase
GII83_03870	COG1653	transport
GII83_03875	COG4209	transmembrane transport
GII83_03880	COG0395	ABC-type sugar transport system, permease component
GII83_03885	COG1486	melibiose metabolic process
GII83_03890	COG2323	membrane
GII83_03895	COG2329	Antibiotic biosynthesis monooxygenase
GII83_03900	COG0346	lactoylglutathione lyase activity
GII83_03915	COG5583	Uncharacterized small protein (DUF2292)
GII83_03920	COG0670	Belongs to the BI1 family
GII83_03925	COG0697	spore germination
GII83_03930	COG1846	Transcriptional regulator
GII83_03935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII83_03950	COG2124	cytochrome p450
GII83_03950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII83_03955	COG1368	sulfuric ester hydrolase activity
GII83_03960	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII83_03965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII83_03970	COG1442	glycosyl transferase family 8
GII83_03975	COG1216	Glycosyl transferase, family 2
GII83_03980	COG1442	glycosyl transferase family 8
GII83_03985	COG2223	nitrite transmembrane transporter activity
GII83_03990	COG1011	Hydrolase
GII83_03995	COG0531	amino acid
GII83_04000	COG1012	belongs to the aldehyde dehydrogenase family
GII83_04005	COG0840	transmembrane signaling receptor activity
GII83_04010	COG0488	(ABC) transporter
GII83_04020	COG0789	Transcriptional regulator
GII83_04025	COG2814	Major facilitator Superfamily
GII83_04035	COG0488	(ABC) transporter
GII83_04040	COG0513	Belongs to the DEAD box helicase family
GII83_04045	COG0456	acetyltransferase
GII83_04050	COG2130	NADP-dependent
GII83_04055	COG2211	Major facilitator Superfamily
GII83_04060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GII83_04065	COG1120	ATPase activity
GII83_04070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII83_04075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII83_04080	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII83_04095	COG3866	Pectate lyase
GII83_04100	COG0471	metal ion transport
GII83_04105	COG3290	protein histidine kinase activity
GII83_04110	COG4565	transcriptional regulatory protein
GII83_04115	COG3181	Tripartite tricarboxylate transporter family receptor
GII83_04120	COG2851	Citrate transporter
GII83_04125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII83_04130	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII83_04135	COG1254	Belongs to the acylphosphatase family
GII83_04140	COG2258	MOSC domain
GII83_04160	COG0024	Methionine aminopeptidase
GII83_04165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_04165	COG1263	PTS System
GII83_04170	COG1368	sulfuric ester hydrolase activity
GII83_04185	COG1115	amino acid carrier protein
GII83_04190	COG0531	amino acid
GII83_04205	COG0697	spore germination
GII83_04210	COG1263	PTS System
GII83_04210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_04215	COG0366	Alpha amylase catalytic
GII83_04220	COG2188	Transcriptional regulator
GII83_04225	COG0778	Nitroreductase
GII83_04230	COG0737	Belongs to the 5'-nucleotidase family
GII83_04235	COG0693	protein deglycase activity
GII83_04240	COG2814	Major facilitator Superfamily
GII83_04245	COG4840	Belongs to the UPF0435 family
GII83_04250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII83_04255	COG4980	gas vesicle protein
GII83_04260	COG1295	ribonuclease BN
GII83_04265	COG0477	Major facilitator Superfamily
GII83_04270	COG0387	Pfam Sodium calcium exchanger
GII83_04280	COG0668	transmembrane transport
GII83_04285	COG0535	radical SAM domain protein
GII83_04295	COG0726	polysaccharide deacetylase
GII83_04300	COG2084	Dehydrogenase
GII83_04305	COG0598	Magnesium transport protein CorA
GII83_04310	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII83_04315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII83_04325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII83_04330	COG4637	Psort location Cytoplasmic, score
GII83_04335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII83_04340	COG0022	dehydrogenase e1 component
GII83_04345	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII83_04350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII83_04355	COG3284	Transcriptional regulator
GII83_04365	COG1742	UPF0060 membrane protein
GII83_04390	COG4842	Belongs to the WXG100 family
GII83_04395	COG1486	melibiose metabolic process
GII83_04400	COG1737	Transcriptional regulator
GII83_04405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_04405	COG1263	PTS System
GII83_04410	COG1132	(ABC) transporter
GII83_04415	COG1132	(ABC) transporter
GII83_04420	COG2259	Doxx family
GII83_04425	COG2514	catechol 2,3-dioxygenase activity
GII83_04430	COG4585	Histidine kinase
GII83_04435	COG2197	response regulator
GII83_04440	COG1131	(ABC) transporter
GII83_04445	COG1511	domain protein
GII83_04445	COG0842	Transport permease protein
GII83_04450	COG0842	Transport permease protein
GII83_04455	COG1695	Transcriptional regulator
GII83_04460	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII83_04465	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII83_04470	COG2318	DinB family
GII83_04475	COG2814	Major facilitator Superfamily
GII83_04480	COG1846	Transcriptional regulator
GII83_04485	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII83_04485	COG0392	lysyltransferase activity
GII83_04490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII83_04495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII83_04500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII83_04505	COG0384	phenazine biosynthesis protein PhzF
GII83_04510	COG0778	Nitroreductase
GII83_04525	COG1090	epimerase
GII83_04530	COG2137	regulation of response to DNA damage stimulus
GII83_04540	COG2814	Major facilitator Superfamily
GII83_04555	COG3103	Sh3 type 3 domain protein
GII83_04560	COG5658	integral membrane protein
GII83_04565	COG0596	Alpha beta hydrolase
GII83_04570	COG0463	Glycosyl transferase, family 2
GII83_04575	COG4485	Bacterial membrane protein, YfhO
GII83_04580	COG1988	membrane-bound metal-dependent
GII83_04585	COG1194	a g-specific adenine glycosylase
GII83_04595	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_04610	COG3557	Belongs to the UPF0374 family
GII83_04615	COG1132	(ABC) transporter
GII83_04620	COG4129	membrane
GII83_04625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII83_04630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII83_04635	COG0735	belongs to the Fur family
GII83_04745	COG4326	sporulation control protein
GII83_04755	COG5577	PFAM Coat F domain
GII83_04760	COG3340	Belongs to the peptidase S51 family
GII83_04765	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII83_04770	COG0277	FAD linked oxidase domain protein
GII83_04780	COG0753	catalase activity
GII83_04785	COG1116	anion transmembrane transporter activity
GII83_04790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII83_04795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII83_04800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII83_04810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII83_04820	COG1476	TRANSCRIPTIONal
GII83_04830	COG3382	B3 4 domain protein
GII83_04835	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII83_04845	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII83_04850	COG0789	Transcriptional regulator
GII83_04855	COG1664	Polymer-forming cytoskeletal
GII83_04860	COG1664	Polymer-forming cytoskeletal
GII83_04865	COG2766	serine protein kinase
GII83_04870	COG2718	Belongs to the UPF0229 family
GII83_04875	COG1846	Transcriptional regulator
GII83_04880	COG1566	PFAM secretion protein HlyD family protein
GII83_04885	COG2814	Major facilitator Superfamily
GII83_04890	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII83_04910	COG1725	Transcriptional regulator
GII83_04915	COG1131	(ABC) transporter
GII83_04920	COG1131	(ABC) transporter
GII83_04925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII83_04930	COG1278	Cold shock
GII83_04935	COG1464	Belongs to the NlpA lipoprotein family
GII83_04940	COG3706	GGDEF domain
GII83_04945	COG1823	symporter activity
GII83_04965	COG5577	PFAM Coat F domain
GII83_04970	COG1525	nuclease
GII83_04970	COG0737	Belongs to the 5'-nucleotidase family
GII83_04970	COG4085	toxin activity
GII83_04975	COG3764	Sortase (surface protein transpeptidase)
GII83_04980	COG0564	pseudouridine synthase activity
GII83_04990	COG0517	IMP dehydrogenase activity
GII83_04995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII83_05000	COG3153	acetyltransferase
GII83_05000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII83_05005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII83_05010	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII83_05015	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII83_05020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII83_05025	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII83_05030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII83_05035	COG4585	Histidine kinase
GII83_05035	COG2203	Gaf domain
GII83_05040	COG2197	response regulator
GII83_05045	COG0431	NADPH-dependent FMN reductase
GII83_05060	COG0791	NLP P60 protein
GII83_05060	COG1388	LysM domain
GII83_05065	COG1959	2 iron, 2 sulfur cluster binding
GII83_05070	COG0668	transmembrane transport
GII83_05075	COG2719	SpoVR family
GII83_05080	COG1785	Belongs to the alkaline phosphatase family
GII83_05085	COG0791	NLP P60 protein
GII83_05085	COG1388	LysM domain
GII83_05090	COG0583	DNA-binding transcription factor activity
GII83_05095	COG0372	Belongs to the citrate synthase family
GII83_05100	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_05105	COG0531	amino acid
GII83_05110	COG0733	neurotransmitter:sodium symporter activity
GII83_05115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII83_05120	COG0456	acetyltransferase
GII83_05135	COG1595	DNA-templated transcription, initiation
GII83_05140	COG0667	Aldo Keto reductase
GII83_05145	COG0204	Acyl-transferase
GII83_05150	COG1253	flavin adenine dinucleotide binding
GII83_05155	COG0789	Transcriptional regulator
GII83_05160	COG0436	Aminotransferase
GII83_05165	COG1253	flavin adenine dinucleotide binding
GII83_05170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII83_05175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII83_05180	COG0584	glycerophosphoryl diester phosphodiesterase
GII83_05190	COG0668	transmembrane transport
GII83_05195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII83_05200	COG0726	polysaccharide deacetylase
GII83_05205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII83_05210	COG1757	Na H antiporter
GII83_05215	COG0589	response to stress
GII83_05225	COG1132	(ABC) transporter
GII83_05230	COG1132	(ABC) transporter
GII83_05235	COG0702	epimerase
GII83_05255	COG0189	ligase activity
GII83_05260	COG0189	ligase activity
GII83_05265	COG4399	Belongs to the UPF0754 family
GII83_05270	COG3679	Belongs to the UPF0342 family
GII83_05275	COG4335	DNA alkylation repair
GII83_05280	COG0561	phosphatase activity
GII83_05285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII83_05290	COG0475	glutathione-regulated potassium exporter activity
GII83_05295	COG0490	domain, Protein
GII83_05305	COG1024	Enoyl-CoA hydratase
GII83_05315	COG4152	abc transporter atp-binding protein
GII83_05320	COG1668	transmembrane transport
GII83_05325	COG0420	3'-5' exonuclease activity
GII83_05330	COG4717	serine-type aminopeptidase activity
GII83_05335	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII83_05345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII83_05375	COG1846	Transcriptional regulator
GII83_05380	COG4980	gas vesicle protein
GII83_05395	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII83_05400	COG0537	adenosine 5'-monophosphoramidase activity
GII83_05405	COG1131	(ABC) transporter
GII83_05410	COG4473	ABC transporter
GII83_05420	COG1473	amidohydrolase
GII83_05425	COG3069	C4-dicarboxylate transmembrane transporter activity
GII83_05435	COG2329	Antibiotic biosynthesis monooxygenase
GII83_05440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII83_05445	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII83_05460	COG1309	transcriptional regulator
GII83_05465	COG1511	domain protein
GII83_05470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII83_05475	COG4377	Putative membrane peptidase family (DUF2324)
GII83_05485	COG1363	Peptidase, m42
GII83_05490	COG4405	Protein conserved in bacteria
GII83_05495	COG1301	dicarboxylic acid transport
GII83_05505	COG1234	tRNA 3'-trailer cleavage
GII83_05510	COG0095	Lipoate-protein ligase
GII83_05515	COG0702	epimerase
GII83_05520	COG0318	PFAM AMP-dependent synthetase and ligase
GII83_05530	COG0501	Belongs to the peptidase M48B family
GII83_05535	COG1404	Belongs to the peptidase S8 family
GII83_05540	COG0456	acetyltransferase
GII83_05545	COG0604	alcohol dehydrogenase
GII83_05550	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII83_05555	COG0406	alpha-ribazole phosphatase activity
GII83_05560	COG0183	Belongs to the thiolase family
GII83_05565	COG0318	PFAM AMP-dependent synthetase and ligase
GII83_05570	COG1268	BioY protein
GII83_05575	COG0840	transmembrane signaling receptor activity
GII83_05580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII83_05580	COG0723	plastoquinol--plastocyanin reductase activity
GII83_05585	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_05595	COG4903	ComK protein
GII83_05600	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_05610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII83_05625	COG0398	Pfam SNARE associated Golgi protein
GII83_05630	COG0681	Belongs to the peptidase S26 family
GII83_05635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII83_05640	COG1846	Transcriptional regulator
GII83_05645	COG0738	Major facilitator superfamily
GII83_05650	COG0673	inositol 2-dehydrogenase activity
GII83_05655	COG0561	phosphatase activity
GII83_05660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII83_05665	COG1609	Transcriptional regulator
GII83_05670	COG3180	Ammonia monooxygenase
GII83_05675	COG0477	Major facilitator Superfamily
GII83_05675	COG2814	Major facilitator Superfamily
GII83_05680	COG4533	DNA binding
GII83_05690	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII83_05695	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII83_05700	COG1074	ATP-dependent DNA helicase activity
GII83_05705	COG0420	3'-5' exonuclease activity
GII83_05710	COG0419	ATPase involved in DNA repair
GII83_05715	COG1403	HNH endonuclease
GII83_05755	COG5337	Spore coat protein CotH
GII83_05760	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII83_05770	COG1404	Belongs to the peptidase S8 family
GII83_05780	COG0367	asparagine synthase
GII83_05785	COG2318	DinB family
GII83_05790	COG1562	ergosterol biosynthetic process
GII83_05795	COG0534	Mate efflux family protein
GII83_05800	COG2207	Transcriptional regulator
GII83_05800	COG1917	Cupin 2, conserved barrel domain protein
GII83_05805	COG1609	Transcriptional regulator
GII83_05810	COG0673	inositol 2-dehydrogenase activity
GII83_05815	COG2318	DinB family
GII83_05820	COG1279	arginine transmembrane transporter activity
GII83_05825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII83_05830	COG1357	PFAM Pentapeptide repeats (8 copies)
GII83_05835	COG2267	carboxylic ester hydrolase activity
GII83_05840	COG0529	Catalyzes the synthesis of activated sulfate
GII83_05845	COG2046	Belongs to the sulfate adenylyltransferase family
GII83_05850	COG0175	sulfate reduction
GII83_05855	COG2045	Belongs to the ComB family
GII83_05860	COG1809	phosphosulfolactate synthase activity
GII83_05865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII83_05870	COG4948	Mandelate Racemase Muconate Lactonizing
GII83_05875	COG2814	Major facilitator Superfamily
GII83_05880	COG0454	-acetyltransferase
GII83_05885	COG2153	protein acetylation
GII83_05890	COG0646	methionine synthase
GII83_05890	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII83_05895	COG1666	GTP binding
GII83_05900	COG2996	Protein conserved in bacteria
GII83_05920	COG1695	Transcriptional regulator
GII83_05935	COG3227	Zinc metalloprotease (Elastase)
GII83_05940	COG1307	EDD domain protein, DegV family
GII83_05945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII83_05960	COG0561	phosphatase activity
GII83_05965	COG1073	alpha beta
GII83_05970	COG2151	metal-sulfur cluster biosynthetic enzyme
GII83_05980	COG0277	FAD linked oxidase domain protein
GII83_05985	COG2271	Major facilitator Superfamily
GII83_05990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII83_06005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII83_06010	COG0505	Belongs to the CarA family
GII83_06015	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII83_06020	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII83_06035	COG2267	carboxylic ester hydrolase activity
GII83_06045	COG1744	ABC transporter substrate-binding protein PnrA-like
GII83_06060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII83_06065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII83_06070	COG5504	Zn-dependent protease
GII83_06075	COG0444	Belongs to the ABC transporter superfamily
GII83_06080	COG4608	Belongs to the ABC transporter superfamily
GII83_06090	COG0601	transmembrane transport
GII83_06095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII83_06105	COG0180	Tryptophanyl-tRNA synthetase
GII83_06110	COG4166	transmembrane transport
GII83_06115	COG0601	transmembrane transport
GII83_06120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII83_06125	COG0444	Belongs to the ABC transporter superfamily
GII83_06130	COG4608	Belongs to the ABC transporter superfamily
GII83_06135	COG2814	Major facilitator Superfamily
GII83_06140	COG0456	acetyltransferase
GII83_06145	COG1393	Belongs to the ArsC family
GII83_06150	COG0861	Integral membrane protein TerC family
GII83_06160	COG4862	establishment of competence for transformation
GII83_06170	COG4469	Competence protein
GII83_06175	COG1164	Oligoendopeptidase f
GII83_06190	COG2346	COG2346, Truncated hemoglobins
GII83_06195	COG0741	lytic transglycosylase activity
GII83_06200	COG4116	CYTH
GII83_06210	COG2357	RelA SpoT domain protein
GII83_06215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII83_06220	COG0564	pseudouridine synthase activity
GII83_06225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII83_06230	COG0569	domain protein
GII83_06230	COG0475	glutathione-regulated potassium exporter activity
GII83_06235	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII83_06240	COG0352	thiamine-phosphate diphosphorylase activity
GII83_06245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII83_06250	COG2104	thiamine diphosphate biosynthetic process
GII83_06255	COG2022	thiamine diphosphate biosynthetic process
GII83_06260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII83_06265	COG0351	phosphomethylpyrimidine kinase
GII83_06270	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII83_06325	COG0210	DNA helicase
GII83_06335	COG2153	protein acetylation
GII83_06340	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII83_06345	COG2382	esterase
GII83_06350	COG0626	cystathionine gamma-synthase activity
GII83_06355	COG0626	cystathionine gamma-synthase activity
GII83_06360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII83_06365	COG5505	Protein of unknown function (DUF819)
GII83_06390	COG5444	nuclease activity
GII83_06435	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII83_06440	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_06450	COG3711	transcriptional antiterminator
GII83_06450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII83_06455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII83_06455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII83_06455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII83_06460	COG1482	cell wall glycoprotein biosynthetic process
GII83_06470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII83_06480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII83_06495	COG0109	protoheme IX farnesyltransferase activity
GII83_06505	COG0726	polysaccharide deacetylase
GII83_06520	COG5504	Zn-dependent protease
GII83_06525	COG2205	protein histidine kinase activity
GII83_06535	COG3383	formate dehydrogenase (NAD+) activity
GII83_06540	COG2427	Protein of unknown function (DUF1641)
GII83_06550	COG1051	belongs to the nudix hydrolase family
GII83_06560	COG2124	cytochrome p450
GII83_06565	COG1819	glycosyl
GII83_06575	COG1587	Uroporphyrinogen-III synthase
GII83_06580	COG0390	transport system, permease component
GII83_06585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII83_06590	COG0697	spore germination
GII83_06595	COG4297	protein containing double-stranded beta helix domain
GII83_06605	COG1252	NADH dehydrogenase
GII83_06610	COG1904	glucuronate isomerase
GII83_06615	COG2211	Major facilitator Superfamily
GII83_06620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII83_06625	COG1063	alcohol dehydrogenase
GII83_06630	COG1312	Catalyzes the dehydration of D-mannonate
GII83_06635	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_06640	COG2271	Major facilitator Superfamily
GII83_06645	COG1609	Transcriptional regulator
GII83_06650	COG0246	Mannitol dehydrogenase
GII83_06655	COG2721	sulfolactate sulfo-lyase activity
GII83_06660	COG0730	response to heat
GII83_06665	COG2318	DinB family
GII83_06670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII83_06675	COG0457	Tetratricopeptide repeat
GII83_06685	COG2350	Protein conserved in bacteria
GII83_06690	COG3409	Peptidoglycan-binding domain 1 protein
GII83_06690	COG1388	LysM domain
GII83_06690	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII83_06700	COG4195	phage-related replication protein
GII83_06705	COG3546	catalase activity
GII83_06710	COG2856	Zn peptidase
GII83_06715	COG1396	sequence-specific DNA binding
GII83_06725	COG1522	sequence-specific DNA binding
GII83_06730	COG1484	DNA-dependent DNA replication
GII83_06750	COG1595	DNA-templated transcription, initiation
GII83_06755	COG3728	DNA packaging
GII83_06755	COG5484	DNA packaging
GII83_06760	COG1783	phage Terminase large subunit
GII83_06765	COG5518	Phage portal protein
GII83_06770	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII83_06775	COG4653	Phage capsid family
GII83_06825	COG3953	SLT domain
GII83_06825	COG5412	phage tail tape measure protein
GII83_06825	COG3953	SLT domain
GII83_06825	COG5412	phage tail tape measure protein
GII83_06830	COG1652	LysM domain
GII83_06835	COG4193	domain, Protein
GII83_06845	COG3628	GPW Gp25 family protein
GII83_06850	COG3299	homolog of phage Mu protein gp47
GII83_06855	COG3778	Protein conserved in bacteria
GII83_06895	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII83_06895	COG3409	Peptidoglycan-binding domain 1 protein
GII83_06915	COG0306	phosphate transporter
GII83_06920	COG1392	Phosphate transport regulator
GII83_06925	COG0531	amino acid
GII83_06930	COG0346	lactoylglutathione lyase activity
GII83_06935	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII83_06940	COG0463	Glycosyl transferase, family 2
GII83_06945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII83_06950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII83_06955	COG2362	D-Aminopeptidase
GII83_06960	COG0601	transmembrane transport
GII83_06965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII83_06970	COG0444	Belongs to the ABC transporter superfamily
GII83_06975	COG4166	transmembrane transport
GII83_06980	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII83_06985	COG4948	Mandelate Racemase Muconate Lactonizing
GII83_06990	COG0791	NLP P60 protein
GII83_06995	COG4608	Belongs to the ABC transporter superfamily
GII83_07000	COG2706	6-phosphogluconolactonase activity
GII83_07005	COG1834	amidinotransferase
GII83_07010	COG1607	acyl-coa hydrolase
GII83_07015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII83_07015	COG1017	nitric oxide dioxygenase activity
GII83_07025	COG2323	membrane
GII83_07030	COG2318	DinB family
GII83_07035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII83_07040	COG2076	Multidrug Resistance protein
GII83_07045	COG2076	Multidrug Resistance protein
GII83_07050	COG0788	formyltetrahydrofolate deformylase activity
GII83_07055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII83_07060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII83_07065	COG1764	response to oxidative stress
GII83_07070	COG1846	Transcriptional regulator
GII83_07075	COG1764	response to oxidative stress
GII83_07080	COG0590	tRNA wobble adenosine to inosine editing
GII83_07085	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII83_07090	COG1404	Belongs to the peptidase S8 family
GII83_07095	COG1366	Belongs to the anti-sigma-factor antagonist family
GII83_07100	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII83_07105	COG1122	ATPase activity
GII83_07110	COG4721	ABC-type cobalt transport system, permease component
GII83_07120	COG0745	RESPONSE REGULATOR receiver
GII83_07125	COG5002	protein histidine kinase activity
GII83_07125	COG3850	Histidine kinase
GII83_07130	COG3212	peptidase
GII83_07135	COG3212	peptidase
GII83_07145	COG2239	Acts as a magnesium transporter
GII83_07150	COG0789	Transcriptional regulator
GII83_07165	COG1846	Transcriptional regulator
GII83_07170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII83_07175	COG0726	polysaccharide deacetylase
GII83_07180	COG1408	metallophosphoesterase
GII83_07190	COG0463	Glycosyl transferase, family 2
GII83_07195	COG1793	dna ligase
GII83_07195	COG3285	dna ligase
GII83_07200	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII83_07205	COG5001	Diguanylate cyclase
GII83_07205	COG3300	MHYT domain
GII83_07210	COG0586	Pfam SNARE associated Golgi protein
GII83_07215	COG0861	Integral membrane protein TerC family
GII83_07220	COG1191	sigma factor activity
GII83_07240	COG0501	Belongs to the peptidase M48B family
GII83_07245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII83_07260	COG3594	Acyltransferase
GII83_07265	COG5002	protein histidine kinase activity
GII83_07270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII83_07280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII83_07285	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII83_07290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII83_07295	COG0436	Aminotransferase
GII83_07300	COG1850	ribulose-bisphosphate carboxylase activity
GII83_07305	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII83_07310	COG0235	Class ii aldolase
GII83_07315	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII83_07320	COG3339	Conserved Protein
GII83_07335	COG3852	Histidine kinase
GII83_07340	COG1846	Transcriptional regulator
GII83_07345	COG1360	Flagellar Motor Protein
GII83_07350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII83_07355	COG0542	response to heat
GII83_07360	COG3949	Membrane
GII83_07365	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII83_07370	COG0720	synthase
GII83_07375	COG0602	queuosine metabolic process
GII83_07380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII83_07385	COG1733	regulation of RNA biosynthetic process
GII83_07390	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_07395	COG1388	LysM domain
GII83_07395	COG4641	Protein conserved in bacteria
GII83_07400	COG1388	LysM domain
GII83_07405	COG3858	chitin binding
GII83_07415	COG4873	Protein conserved in bacteria
GII83_07425	COG3773	Cell wall hydrolase
GII83_07430	COG2244	polysaccharide biosynthetic process
GII83_07435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII83_07440	COG2217	Heavy metal translocating P-type atpase
GII83_07450	COG0006	proline dipeptidase activity
GII83_07455	COG1609	Transcriptional regulator
GII83_07460	COG3711	transcriptional antiterminator
GII83_07465	COG2190	(PTS) system
GII83_07465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_07465	COG1263	PTS System
GII83_07470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII83_07475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII83_07485	COG1533	DNA photolyase activity
GII83_07490	COG0456	acetyltransferase
GII83_07495	COG0840	transmembrane signaling receptor activity
GII83_07500	COG2084	Dehydrogenase
GII83_07505	COG2340	Cysteine-rich secretory protein family
GII83_07510	COG0768	penicillin binding
GII83_07515	COG4191	Histidine kinase
GII83_07520	COG0436	Aminotransferase
GII83_07530	COG0835	chemotaxis
GII83_07530	COG0784	Response regulator, receiver
GII83_07540	COG2814	Major facilitator Superfamily
GII83_07545	COG1376	ErfK ybiS ycfS ynhG family protein
GII83_07550	COG1408	metallophosphoesterase
GII83_07555	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_07560	COG2200	EAL domain
GII83_07565	COG4703	Protein of unknown function (DUF1797)
GII83_07570	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII83_07580	COG0517	IMP dehydrogenase activity
GII83_07585	COG0583	DNA-binding transcription factor activity
GII83_07590	COG0716	FMN binding
GII83_07600	COG0716	FMN binding
GII83_07605	COG2171	N-acyltransferase activity
GII83_07610	COG1473	amidohydrolase
GII83_07620	COG0668	transmembrane transport
GII83_07625	COG0450	alkyl hydroperoxide reductase
GII83_07630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII83_07645	COG0746	molybdenum cofactor guanylyltransferase activity
GII83_07650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII83_07655	COG0303	'Molybdopterin
GII83_07660	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII83_07665	COG0314	molybdopterin synthase activity
GII83_07670	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII83_07675	COG1132	(ABC) transporter
GII83_07680	COG1132	(ABC) transporter
GII83_07690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII83_07695	COG1136	(ABC) transporter
GII83_07700	COG0577	efflux transmembrane transporter activity
GII83_07705	COG1349	DNA-binding transcription factor activity
GII83_07710	COG1105	Belongs to the carbohydrate kinase PfkB family
GII83_07715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII83_07715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII83_07715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII83_07720	COG0681	Belongs to the peptidase S26 family
GII83_07730	COG0488	(ABC) transporter
GII83_07735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII83_07740	COG2309	aminopeptidase activity
GII83_07750	COG1077	Cell shape determining protein MreB Mrl
GII83_07755	COG2002	toxin-antitoxin pair type II binding
GII83_07760	COG3852	Histidine kinase
GII83_07765	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII83_07765	COG2105	PFAM AIG2 family protein
GII83_07770	COG0569	domain protein
GII83_07775	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII83_07780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII83_07790	COG0561	phosphatase activity
GII83_07795	COG0242	peptide deformylase activity
GII83_07805	COG0497	DNA recombination
GII83_07810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII83_07815	COG0022	dehydrogenase e1 component
GII83_07820	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII83_07825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII83_07830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII83_07840	COG1982	Orn Lys Arg decarboxylase major
GII83_07845	COG4476	Belongs to the UPF0223 family
GII83_07850	COG4493	Belongs to the UPF0637 family
GII83_07860	COG0483	inositol monophosphate 1-phosphatase activity
GII83_07870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII83_07890	COG1595	DNA-templated transcription, initiation
GII83_07920	COG4896	Protein conserved in bacteria
GII83_07930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII83_07935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII83_07940	COG2066	Belongs to the glutaminase family
GII83_07945	COG4838	Belongs to the UPF0358 family
GII83_07950	COG0772	Belongs to the SEDS family
GII83_07955	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII83_07960	COG1612	heme a metabolic process
GII83_07965	COG0109	protoheme IX farnesyltransferase activity
GII83_07970	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII83_07970	COG2010	Cytochrome c
GII83_07975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII83_07980	COG1845	cytochrome c oxidase, subunit III
GII83_07985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII83_07990	COG3336	cytochrome c oxidase
GII83_08000	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII83_08005	COG2340	Cysteine-rich secretory protein family
GII83_08020	COG3679	Belongs to the UPF0342 family
GII83_08025	COG4471	UPF0298 protein
GII83_08030	COG0742	ribosomal rna small subunit methyltransferase
GII83_08035	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII83_08040	COG3314	Sporulation integral membrane protein YlbJ
GII83_08045	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII83_08050	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII83_08055	COG1323	Belongs to the UPF0348 family
GII83_08065	COG1399	metal-binding, possibly nucleic acid-binding protein
GII83_08070	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GII83_08080	COG0454	-acetyltransferase
GII83_08085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII83_08090	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII83_08095	COG2001	Belongs to the MraZ family
GII83_08100	COG0275	rRNA processing
GII83_08105	COG4839	cell division protein FtsL
GII83_08115	COG0768	penicillin binding
GII83_08120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII83_08125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII83_08130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII83_08135	COG0772	Belongs to the SEDS family
GII83_08140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII83_08145	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII83_08150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII83_08155	COG3879	Bacterial protein of unknown function (DUF881)
GII83_08160	COG3879	Bacterial protein of unknown function (DUF881)
GII83_08165	COG3856	small basic protein
GII83_08170	COG0849	cell division
GII83_08175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII83_08180	COG4412	M6 family metalloprotease domain protein
GII83_08180	COG1404	Belongs to the peptidase S8 family
GII83_08190	COG1191	sigma factor activity
GII83_08195	COG1191	sigma factor activity
GII83_08200	COG1119	ATPase activity
GII83_08205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII83_08210	COG1873	PFAM PRC-barrel domain
GII83_08220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII83_08225	COG1799	cell septum assembly
GII83_08230	COG0762	integral membrane protein
GII83_08235	COG2302	S4 RNA-binding domain
GII83_08240	COG3599	regulation of cell shape
GII83_08245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII83_08250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII83_08255	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII83_08260	COG0564	pseudouridine synthase activity
GII83_08265	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII83_08270	COG2233	PERMEase
GII83_08275	COG0540	Belongs to the ATCase OTCase family
GII83_08280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII83_08285	COG0505	Belongs to the CarA family
GII83_08290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII83_08295	COG0543	2 iron, 2 sulfur cluster binding
GII83_08300	COG0167	dihydroorotate dehydrogenase activity
GII83_08305	COG0284	orotidine-5'-phosphate decarboxylase activity
GII83_08310	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII83_08315	COG0175	sulfate reduction
GII83_08320	COG0306	phosphate transporter
GII83_08325	COG2046	Belongs to the sulfate adenylyltransferase family
GII83_08330	COG0529	Catalyzes the synthesis of activated sulfate
GII83_08335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII83_08340	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII83_08345	COG1648	precorrin-2 dehydrogenase activity
GII83_08355	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII83_08360	COG1561	YicC-like family, N-terminal region
GII83_08365	COG2052	Domain of unknown function (DUF370)
GII83_08370	COG0194	GDP metabolic process
GII83_08375	COG1758	RNA polymerase activity
GII83_08380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII83_08385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII83_08390	COG0242	peptide deformylase activity
GII83_08395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII83_08400	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII83_08400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII83_08405	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII83_08410	COG0631	protein serine/threonine phosphatase activity
GII83_08415	COG2815	serine threonine protein kinase
GII83_08415	COG0515	serine threonine protein kinase
GII83_08420	COG1162	GTPase activity
GII83_08425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII83_08430	COG1564	THIamine pyrophosphokinase
GII83_08440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII83_08445	COG1302	Protein conserved in bacteria
GII83_08450	COG1461	Dihydroxyacetone kinase
GII83_08455	COG1760	l-serine dehydratase
GII83_08460	COG1760	l-serine dehydratase
GII83_08465	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII83_08470	COG2050	protein possibly involved in aromatic compounds catabolism
GII83_08470	COG1349	DNA-binding transcription factor activity
GII83_08475	COG0416	fatty acid biosynthetic process
GII83_08480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII83_08485	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_08490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII83_08495	COG0571	ribonuclease III activity
GII83_08500	COG1196	nuclear chromosome segregation
GII83_08505	COG0552	protein localization to endoplasmic reticulum
GII83_08515	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII83_08520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII83_08525	COG0228	four-way junction DNA binding
GII83_08530	COG1837	Belongs to the UPF0109 family
GII83_08540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII83_08545	COG0336	Belongs to the RNA methyltransferase TrmD family
GII83_08550	COG0335	large ribosomal subunit rRNA binding
GII83_08555	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII83_08560	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII83_08570	COG2257	FlhB HrpN YscU SpaS Family
GII83_08575	COG0045	succinate-CoA ligase (ADP-forming) activity
GII83_08580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII83_08585	COG0758	DNA mediated transformation
GII83_08590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII83_08595	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII83_08600	COG4974	Belongs to the 'phage' integrase family
GII83_08605	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII83_08610	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII83_08615	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII83_08620	COG1815	bacterial-type flagellum-dependent cell motility
GII83_08625	COG1558	bacterial-type flagellum-dependent cell motility
GII83_08630	COG1677	Flagellar hook-basal body complex protein FliE
GII83_08635	COG1766	The M ring may be actively involved in energy transduction
GII83_08640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII83_08645	COG1317	bacterial-type flagellum organization
GII83_08650	COG1157	protein secretion by the type III secretion system
GII83_08655	COG2882	bacterial-type flagellum organization
GII83_08660	COG3334	PFAM MgtE intracellular
GII83_08665	COG3144	bacterial-type flagellum assembly
GII83_08670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII83_08675	COG4786	Flagellar basal body rod
GII83_08680	COG1582	Flagellar protein (FlbD)
GII83_08685	COG1580	Controls the rotational direction of flagella during chemotaxis
GII83_08690	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII83_08695	COG1776	CheC inhibitor of MCP methylation
GII83_08695	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII83_08700	COG2201	protein-glutamate methylesterase activity
GII83_08705	COG3190	flagellar
GII83_08710	COG1338	Plays a role in the flagellum-specific transport system
GII83_08715	COG1987	bacterial-type flagellum assembly
GII83_08720	COG1684	flagellar biosynthetic protein fliR
GII83_08725	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII83_08730	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII83_08735	COG1419	protein localization to endoplasmic reticulum
GII83_08740	COG0455	bacterial-type flagellum organization
GII83_08745	COG2201	protein-glutamate methylesterase activity
GII83_08750	COG2198	Histidine kinase
GII83_08750	COG0643	Histidine kinase
GII83_08755	COG0835	chemotaxis
GII83_08760	COG1776	CheC inhibitor of MCP methylation
GII83_08765	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII83_08770	COG1191	sigma factor activity
GII83_08780	COG0052	Belongs to the universal ribosomal protein uS2 family
GII83_08785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII83_08790	COG0528	UMP kinase activity
GII83_08795	COG0233	cytoplasmic translational termination
GII83_08800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII83_08805	COG4589	Belongs to the CDS family
GII83_08810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII83_08815	COG0750	zinc metalloprotease
GII83_08820	COG0442	prolyl-tRNA aminoacylation
GII83_08825	COG2176	DNA-directed DNA polymerase activity
GII83_08830	COG0779	Required for maturation of 30S ribosomal subunits
GII83_08835	COG0195	Participates in both transcription termination and antitermination
GII83_08840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII83_08845	COG1358	cellular component organization or biogenesis
GII83_08850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII83_08855	COG1550	Protein conserved in bacteria
GII83_08860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII83_08865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII83_08870	COG0196	riboflavin kinase activity
GII83_08875	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII83_08880	COG1185	polyribonucleotide nucleotidyltransferase activity
GII83_08885	COG0726	polysaccharide deacetylase
GII83_08890	COG0612	Peptidase, M16
GII83_08895	COG1873	PFAM PRC-barrel domain
GII83_08900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII83_08905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII83_08910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII83_08915	COG0527	aspartate kinase activity
GII83_08920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII83_08925	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII83_08930	COG0740	serine-type endopeptidase activity
GII83_08940	COG4980	gas vesicle protein
GII83_08940	COG1674	ftsk spoiiie
GII83_08945	COG2188	Transcriptional regulator
GII83_08950	COG2814	Major facilitator Superfamily
GII83_08955	COG0612	Peptidase, M16
GII83_08960	COG0612	Peptidase, M16
GII83_08965	COG0300	oxidoreductase activity
GII83_08980	COG1426	Protein conserved in bacteria
GII83_08985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII83_08990	COG1546	Belongs to the CinA family
GII83_08990	COG1058	Belongs to the CinA family
GII83_08995	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII83_09000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII83_09005	COG1418	mRNA catabolic process
GII83_09010	COG1692	metallophosphoesterase
GII83_09015	COG2359	stage V sporulation protein S
GII83_09020	COG1063	alcohol dehydrogenase
GII83_09025	COG0156	8-amino-7-oxononanoate synthase activity
GII83_09030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII83_09035	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII83_09045	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII83_09050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII83_09065	COG3226	Transcriptional regulator
GII83_09070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII83_09080	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII83_09085	COG3321	synthase
GII83_09090	COG2070	2-Nitropropane dioxygenase
GII83_09090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII83_09095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII83_09100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII83_09105	COG3425	synthase
GII83_09110	COG1024	Enoyl-CoA hydratase
GII83_09115	COG1024	Enoyl-CoA hydratase
GII83_09120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_09120	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_09120	COG0318	PFAM AMP-dependent synthetase and ligase
GII83_09120	COG3321	synthase
GII83_09120	COG0300	oxidoreductase activity
GII83_09125	COG0300	oxidoreductase activity
GII83_09125	COG3321	synthase
GII83_09125	COG4221	oxidoreductase activity
GII83_09125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII83_09130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_09130	COG3321	synthase
GII83_09130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII83_09130	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_09130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII83_09135	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_09135	COG4221	oxidoreductase activity
GII83_09135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_09135	COG3321	synthase
GII83_09140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII83_09140	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII83_09140	COG3321	synthase
GII83_09140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GII83_09145	COG2124	cytochrome p450
GII83_09155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII83_09160	COG1404	Belongs to the peptidase S8 family
GII83_09170	COG4195	phage-related replication protein
GII83_09175	COG1764	response to oxidative stress
GII83_09180	COG2076	Multidrug Resistance protein
GII83_09185	COG2076	Multidrug Resistance protein
GII83_09200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII83_09205	COG1923	regulation of RNA biosynthetic process
GII83_09220	COG1780	Probably involved in ribonucleotide reductase function
GII83_09225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII83_09230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII83_09235	COG4112	unkown
GII83_09240	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII83_09245	COG0464	growth
GII83_09250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII83_09255	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII83_09260	COG0789	Transcriptional regulator
GII83_09265	COG0174	glutamine synthetase
GII83_09300	COG1598	PFAM Uncharacterised protein family UPF0150
GII83_09380	COG0463	Glycosyl transferase, family 2
GII83_09395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII83_09410	COG3655	Transcriptional regulator
GII83_09425	COG0135	phosphoribosylanthranilate isomerase activity
GII83_09435	COG2211	Major facilitator Superfamily
GII83_09440	COG3507	Belongs to the glycosyl hydrolase 43 family
GII83_09445	COG1940	carbohydrate kinase activity
GII83_09450	COG2115	Belongs to the xylose isomerase family
GII83_09455	COG1070	Carbohydrate kinase
GII83_09465	COG1525	nuclease
GII83_09470	COG2814	Major facilitator Superfamily
GII83_09475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII83_09485	COG0756	dUTP diphosphatase activity
GII83_09520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII83_09530	COG3832	glyoxalase III activity
GII83_09575	COG4195	phage-related replication protein
GII83_09585	COG0346	lactoylglutathione lyase activity
GII83_09590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII83_09595	COG1388	LysM domain
GII83_09600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII83_09605	COG4224	UPF0291 protein
GII83_09610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII83_09620	COG3763	UPF0154 protein
GII83_09630	COG0785	Cytochrome C biogenesis protein
GII83_09635	COG2201	protein-glutamate methylesterase activity
GII83_09640	COG4846	Membrane protein involved in cytochrome C biogenesis
GII83_09650	COG0071	Belongs to the small heat shock protein (HSP20) family
GII83_09665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII83_09670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII83_09690	COG0824	Thioesterase
GII83_09700	COG4841	protein insertion into membrane
GII83_09705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII83_09710	COG1832	CoA-binding protein
GII83_09715	COG0187	DNA topoisomerase II activity
GII83_09720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII83_09730	COG1115	amino acid carrier protein
GII83_09745	COG5520	Belongs to the glycosyl hydrolase 30 family
GII83_09750	COG3507	Belongs to the glycosyl hydrolase 43 family
GII83_09755	COG2246	polysaccharide biosynthetic process
GII83_09760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII83_09765	COG0586	Pfam SNARE associated Golgi protein
GII83_09770	COG2404	hydrolase activity, acting on ester bonds
GII83_09775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII83_09780	COG1024	Enoyl-CoA hydratase
GII83_09785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII83_09790	COG0511	ligase activity, forming carbon-carbon bonds
GII83_09795	COG0439	Biotin carboxylase
GII83_09800	COG0318	PFAM AMP-dependent synthetase and ligase
GII83_09805	COG1960	acyl-CoA dehydrogenase activity
GII83_09820	COG1649	PFAM Uncharacterised BCR, COG1649
GII83_09830	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII83_09830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_09835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_09840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_09850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_09855	COG2027	D-alanyl-D-alanine carboxypeptidase
GII83_09860	COG2017	converts alpha-aldose to the beta-anomer
GII83_09865	COG0534	Mate efflux family protein
GII83_09880	COG0582	viral genome integration into host DNA
GII83_09885	COG0166	Belongs to the GPI family
GII83_09890	COG0405	Gamma-glutamyltransferase
GII83_09895	COG0583	DNA-binding transcription factor activity
GII83_09900	COG0604	alcohol dehydrogenase
GII83_09905	COG0493	'glutamate synthase
GII83_09910	COG0070	glutamate synthase
GII83_09910	COG0069	glutamate synthase activity
GII83_09910	COG0067	glutamate synthase
GII83_09915	COG0583	DNA-binding transcription factor activity
GII83_09920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII83_09925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII83_09935	COG0300	oxidoreductase activity
GII83_09940	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII83_09950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII83_09965	COG2814	Major facilitator Superfamily
GII83_09970	COG1070	Carbohydrate kinase
GII83_09975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII83_09980	COG0243	molybdopterin cofactor binding
GII83_10010	COG0840	transmembrane signaling receptor activity
GII83_10010	COG5278	phosphoserine phosphatase activity
GII83_10015	COG2368	4-hydroxyphenylacetate
GII83_10020	COG4305	rare lipoprotein A
GII83_10025	COG3619	membrane
GII83_10030	COG3866	Pectate lyase
GII83_10035	COG2135	peptidase activity
GII83_10045	COG2140	Oxalate decarboxylase
GII83_10055	COG0456	acetyltransferase
GII83_10075	COG2720	vancomycin resistance protein
GII83_10085	COG3655	Transcriptional regulator
GII83_10090	COG3739	integral membrane protein
GII83_10095	COG0583	DNA-binding transcription factor activity
GII83_10100	COG0697	spore germination
GII83_10110	COG0693	protein deglycase activity
GII83_10115	COG2367	Beta-lactamase
GII83_10140	COG3848	Pyruvate phosphate dikinase
GII83_10140	COG0574	Belongs to the PEP-utilizing enzyme family
GII83_10145	COG0726	polysaccharide deacetylase
GII83_10150	COG2314	TM2 domain
GII83_10155	COG1396	sequence-specific DNA binding
GII83_10225	COG3655	Transcriptional regulator
GII83_10235	COG1404	Belongs to the peptidase S8 family
GII83_10265	COG0457	Tetratricopeptide repeat
GII83_10300	COG4282	regulation of fungal-type cell wall biogenesis
GII83_10305	COG1231	oxidoreductase activity
GII83_10310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII83_10315	COG0662	Cupin 2, conserved barrel domain protein
GII83_10315	COG2207	Transcriptional regulator
GII83_10320	COG0456	acetyltransferase
GII83_10325	COG1309	transcriptional regulator
GII83_10330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII83_10335	COG3708	Transcriptional regulator
GII83_10340	COG2378	regulation of single-species biofilm formation
GII83_10350	COG0640	Transcriptional regulator
GII83_10355	COG0741	lytic transglycosylase activity
GII83_10360	COG2322	membrane
GII83_10375	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII83_10380	COG3239	Fatty acid desaturase
GII83_10385	COG4585	Histidine kinase
GII83_10390	COG2197	response regulator
GII83_10395	COG1388	LysM domain
GII83_10395	COG3584	3D domain protein
GII83_10400	COG0514	ATP-dependent DNA helicase (RecQ)
GII83_10410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII83_10415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII83_10430	COG0071	Belongs to the small heat shock protein (HSP20) family
GII83_10455	COG1012	belongs to the aldehyde dehydrogenase family
GII83_10460	COG1657	PFAM Prenyltransferase squalene oxidase
GII83_10465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII83_10470	COG0733	neurotransmitter:sodium symporter activity
GII83_10475	COG0385	Bile acid
GII83_10480	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII83_10485	COG0567	Dehydrogenase, E1 component
GII83_10490	COG4548	von Willebrand factor, type A
GII83_10495	COG0714	Associated with various cellular activities
GII83_10500	COG2032	superoxide dismutase activity
GII83_10505	COG1388	LysM domain
GII83_10505	COG0791	NLP P60 protein
GII83_10510	COG1819	glycosyl
GII83_10515	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII83_10520	COG0534	Mate efflux family protein
GII83_10525	COG1366	Belongs to the anti-sigma-factor antagonist family
GII83_10530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII83_10535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII83_10545	COG2962	Rard protein
GII83_10560	COG2610	gluconate transmembrane transporter activity
GII83_10565	COG1942	4-Oxalocrotonate Tautomerase
GII83_10570	COG1733	regulation of RNA biosynthetic process
GII83_10575	COG0778	Nitroreductase
GII83_10580	COG0400	carboxylic ester hydrolase activity
GII83_10585	COG0346	lactoylglutathione lyase activity
GII83_10595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII83_10600	COG0793	Belongs to the peptidase S41A family
GII83_10600	COG3409	Peptidoglycan-binding domain 1 protein
GII83_10605	COG2226	methyltransferase
GII83_10615	COG1876	peptidase activity
GII83_10620	COG0813	purine-nucleoside phosphorylase activity
GII83_10635	COG0671	phosphoesterase, PA-phosphatase related
GII83_10655	COG4479	Belongs to the UPF0346 family
GII83_10665	COG1509	lysine 2,3-aminomutase activity
GII83_10670	COG0456	acetyltransferase
GII83_10675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII83_10680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII83_10685	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII83_10690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII83_10705	COG0456	acetyltransferase
GII83_10710	COG0463	Glycosyl transferase, family 2
GII83_10725	COG4641	Protein conserved in bacteria
GII83_10730	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII83_10735	COG1086	Polysaccharide biosynthesis protein
GII83_10740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII83_10745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII83_10750	COG1846	Transcriptional regulator
GII83_10755	COG0534	Mate efflux family protein
GII83_10765	COG4698	Protein conserved in bacteria
GII83_10770	COG2755	lipolytic protein G-D-S-L family
GII83_10775	COG1999	signal sequence binding
GII83_10785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII83_10790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII83_10795	COG1272	protein, Hemolysin III
GII83_10800	COG0204	Acyl-transferase
GII83_10805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII83_10810	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII83_10815	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII83_10825	COG2521	methyltransferase
GII83_10825	COG2136	Putative SAM-dependent methyltransferase
GII83_10835	COG0129	dihydroxy-acid dehydratase activity
GII83_10840	COG1413	lyase activity
GII83_10845	COG1418	mRNA catabolic process
GII83_10850	COG0386	Belongs to the glutathione peroxidase family
GII83_10855	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII83_10860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII83_10870	COG1278	Cold shock
GII83_10890	COG0328	RNA-DNA hybrid ribonuclease activity
GII83_10895	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII83_10900	COG0328	RNA-DNA hybrid ribonuclease activity
GII83_10910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII83_10925	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII83_10935	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII83_10940	COG3424	synthase
GII83_10945	COG2233	PERMEase
GII83_10950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII83_10955	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII83_10965	COG0800	Aldolase
GII83_10970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII83_10975	COG1609	Transcriptional regulator
GII83_10980	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII83_10985	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_10990	COG1199	ATP-dependent helicase activity
GII83_11005	COG0116	Belongs to the methyltransferase superfamily
GII83_11020	COG4474	Belongs to the UPF0398 family
GII83_11035	COG3359	exonuclease
GII83_11040	COG1111	helicase
GII83_11040	COG1205	dead DEAH box helicase
GII83_11045	COG2190	(PTS) system
GII83_11050	COG0071	Belongs to the small heat shock protein (HSP20) family
GII83_11085	COG3331	DNA recombination
GII83_11090	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII83_11090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII83_11100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII83_11105	COG3935	DnaD domain protein
GII83_11110	COG0017	Asparaginyl-tRNA synthetase
GII83_11115	COG0436	Aminotransferase
GII83_11120	COG5353	protein conserved in bacteria
GII83_11130	COG1199	ATP-dependent helicase activity
GII83_11130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII83_11135	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII83_11140	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII83_11145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII83_11150	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII83_11150	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII83_11155	COG0617	tRNA 3'-terminal CCA addition
GII83_11160	COG0438	transferase activity, transferring glycosyl groups
GII83_11165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII83_11170	COG1803	Methylglyoxal synthase
GII83_11175	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII83_11180	COG1694	Mazg nucleotide pyrophosphohydrolase
GII83_11185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII83_11195	COG4347	Protein of unknown function (DUF1405)
GII83_11200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII83_11200	COG2010	Cytochrome c
GII83_11205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII83_11210	COG0723	plastoquinol--plastocyanin reductase activity
GII83_11220	COG5582	Belongs to the UPF0302 family
GII83_11225	COG0457	Tetratricopeptide repeat
GII83_11230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII83_11235	COG0287	Prephenate dehydrogenase
GII83_11240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GII83_11250	COG0133	tryptophan synthase activity
GII83_11255	COG0135	phosphoribosylanthranilate isomerase activity
GII83_11265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII83_11270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII83_11275	COG4401	Chorismate mutase type I
GII83_11280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII83_11285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII83_11290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII83_11295	COG0105	UTP biosynthetic process
GII83_11300	COG0142	geranyltranstransferase activity
GII83_11305	COG2226	methyltransferase
GII83_11310	COG0142	geranyltranstransferase activity
GII83_11320	COG0302	gtp cyclohydrolase
GII83_11325	COG0776	regulation of translation
GII83_11330	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII83_11345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII83_11350	COG1160	GTP binding
GII83_11375	COG1304	FMN binding
GII83_11380	COG0539	negative regulation of cytoplasmic translation
GII83_11385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII83_11395	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII83_11400	COG2959	enzyme of heme biosynthesis
GII83_11405	COG3409	Peptidoglycan-binding domain 1 protein
GII83_11405	COG3773	Cell wall hydrolase
GII83_11410	COG2339	peptidase activity
GII83_11415	COG0492	ferredoxin-NADP+ reductase activity
GII83_11420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII83_11425	COG4862	establishment of competence for transformation
GII83_11430	COG1408	metallophosphoesterase
GII83_11440	COG1388	LysM domain
GII83_11445	COG1266	CAAX protease self-immunity
GII83_11450	COG0514	ATP-dependent DNA helicase (RecQ)
GII83_11455	COG4955	Helix-turn-helix domain
GII83_11460	COG1141	Ferredoxin
GII83_11465	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII83_11470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII83_11475	COG0710	3-dehydroquinate dehydratase activity
GII83_11485	COG1595	DNA-templated transcription, initiation
GII83_11490	COG5002	protein histidine kinase activity
GII83_11495	COG0745	RESPONSE REGULATOR receiver
GII83_11500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII83_11505	COG1333	cytochrome c biogenesis protein
GII83_11510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII83_11515	COG1187	pseudouridine synthase activity
GII83_11520	COG0700	Nucleoside recognition
GII83_11525	COG2715	membrane protein required for spore maturation
GII83_11530	COG1686	Belongs to the peptidase S11 family
GII83_11540	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII83_11545	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII83_11550	COG1547	Domain of unknown function (DUF309)
GII83_11555	COG0456	acetyltransferase
GII83_11560	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII83_11565	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII83_11565	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII83_11570	COG0307	riboflavin synthase, alpha
GII83_11575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII83_11575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII83_11585	COG0681	Belongs to the peptidase S26 family
GII83_11595	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII83_11620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII83_11625	COG4086	secreted protein
GII83_11630	COG0019	diaminopimelate decarboxylase activity
GII83_11635	COG0697	spore germination
GII83_11650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII83_11670	COG1191	sigma factor activity
GII83_11675	COG2172	sigma factor antagonist activity
GII83_11680	COG1366	Belongs to the anti-sigma-factor antagonist family
GII83_11685	COG1686	Belongs to the peptidase S11 family
GII83_11690	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII83_11695	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII83_11700	COG4974	Belongs to the 'phage' integrase family
GII83_11710	COG0735	belongs to the Fur family
GII83_11715	COG1300	Membrane
GII83_11725	COG0281	malic enzyme
GII83_11730	COG1757	Na H antiporter
GII83_11735	COG1027	Aspartate ammonia-lyase
GII83_11740	COG0252	asparaginase activity
GII83_11745	COG1396	sequence-specific DNA binding
GII83_11750	COG1379	DNA repair
GII83_11755	COG0494	nUDIX hydrolase
GII83_11765	COG0667	Aldo Keto reductase
GII83_11775	COG1073	alpha beta
GII83_11785	COG4918	Iron-sulphur cluster biosynthesis
GII83_11790	COG0456	acetyltransferase
GII83_11790	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII83_11795	COG2329	Antibiotic biosynthesis monooxygenase
GII83_11800	COG0456	acetyltransferase
GII83_11810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII83_11820	COG2211	Major facilitator Superfamily
GII83_11825	COG0346	lactoylglutathione lyase activity
GII83_11830	COG1072	(Pantothenic acid kinase))
GII83_11835	COG3048	D-serine ammonia-lyase activity
GII83_11840	COG0300	oxidoreductase activity
GII83_11845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII83_11850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII83_11855	COG4187	Peptidase family M20/M25/M40
GII83_11860	COG1902	pentaerythritol trinitrate reductase activity
GII83_11865	COG0596	Alpha beta hydrolase
GII83_11875	COG1234	tRNA 3'-trailer cleavage
GII83_11880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII83_11885	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII83_11890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII83_11900	COG0706	membrane insertase activity
GII83_11905	COG3361	conserved protein (COG2071)
GII83_11910	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII83_11915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII83_11920	COG0346	lactoylglutathione lyase activity
GII83_11930	COG1376	ErfK ybiS ycfS ynhG family protein
GII83_11935	COG4129	membrane
GII83_11940	COG1126	abc transporter atp-binding protein
GII83_11945	COG0765	amino acid transport
GII83_11950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII83_11960	COG1597	lipid kinase activity
GII83_11965	COG2814	Major facilitator Superfamily
GII83_11970	COG4978	Transcriptional regulator
GII83_11970	COG0789	Transcriptional regulator
GII83_11975	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII83_11980	COG0022	dehydrogenase e1 component
GII83_11985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII83_11990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII83_11995	COG3426	butyrate kinase activity
GII83_12000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII83_12005	COG0280	phosphate acetyltransferase
GII83_12010	COG3829	transcription factor binding
GII83_12010	COG3290	protein histidine kinase activity
GII83_12020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII83_12025	COG2079	MmgE PrpD family protein
GII83_12030	COG0372	Belongs to the citrate synthase family
GII83_12035	COG1960	acyl-CoA dehydrogenase activity
GII83_12040	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII83_12045	COG0183	Belongs to the thiolase family
GII83_12050	COG0584	glycerophosphoryl diester phosphodiesterase
GII83_12055	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII83_12070	COG1902	pentaerythritol trinitrate reductase activity
GII83_12075	COG0745	RESPONSE REGULATOR receiver
GII83_12080	COG0750	zinc metalloprotease
GII83_12085	COG0497	DNA recombination
GII83_12090	COG1438	arginine binding
GII83_12095	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII83_12100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII83_12105	COG0142	geranyltranstransferase activity
GII83_12110	COG1722	exodeoxyribonuclease VII activity
GII83_12115	COG1570	exodeoxyribonuclease VII activity
GII83_12120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII83_12125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII83_12130	COG1302	Protein conserved in bacteria
GII83_12135	COG0439	Biotin carboxylase
GII83_12140	COG0511	ligase activity, forming carbon-carbon bonds
GII83_12180	COG3854	ATPases associated with a variety of cellular activities
GII83_12190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII83_12195	COG0006	proline dipeptidase activity
GII83_12200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII83_12210	COG3872	metal-dependent enzyme
GII83_12220	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII83_12225	COG1321	iron dependent repressor
GII83_12230	COG0095	Lipoate-protein ligase
GII83_12235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII83_12240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII83_12245	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII83_12250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII83_12255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII83_12270	COG1396	sequence-specific DNA binding
GII83_12280	COG0681	Belongs to the peptidase S26 family
GII83_12305	COG4940	Competence protein ComGF
GII83_12315	COG4970	Tfp pilus assembly protein FimT
GII83_12320	COG4537	Required for transformation and DNA binding
GII83_12325	COG1459	type II secretion system
GII83_12330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII83_12335	COG0517	IMP dehydrogenase activity
GII83_12340	COG0598	Magnesium transport protein CorA
GII83_12345	COG1253	flavin adenine dinucleotide binding
GII83_12350	COG1366	Belongs to the anti-sigma-factor antagonist family
GII83_12360	COG1393	Belongs to the ArsC family
GII83_12370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII83_12380	COG0011	TIGRFAM Protein of
GII83_12390	COG2866	Carboxypeptidase
GII83_12395	COG1368	sulfuric ester hydrolase activity
GII83_12400	COG1940	carbohydrate kinase activity
GII83_12405	COG4483	Protein conserved in bacteria
GII83_12410	COG0457	Tetratricopeptide repeat
GII83_12410	COG0705	Rhomboid family
GII83_12420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII83_12425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII83_12430	COG0438	transferase activity, transferring glycosyl groups
GII83_12445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII83_12450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII83_12455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII83_12460	COG0581	inorganic phosphate transmembrane transporter activity
GII83_12465	COG0573	inorganic phosphate transmembrane transporter activity
GII83_12470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII83_12480	COG0477	Major facilitator Superfamily
GII83_12485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII83_12490	COG2839	Protein conserved in bacteria
GII83_12495	COG5521	maltodextrose utilization protein MalA
GII83_12500	COG1388	LysM domain
GII83_12505	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII83_12510	COG4709	membrane
GII83_12515	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII83_12520	COG0735	belongs to the Fur family
GII83_12525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII83_12535	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII83_12540	COG0513	Belongs to the DEAD box helicase family
GII83_12550	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII83_12555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII83_12560	COG2384	SAM-dependent methyltransferase
GII83_12565	COG2010	Cytochrome c
GII83_12570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII83_12575	COG0358	DNA primase activity
GII83_12580	COG1671	Belongs to the UPF0178 family
GII83_12585	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII83_12590	COG0517	IMP dehydrogenase activity
GII83_12595	COG0751	glycine-tRNA ligase activity
GII83_12600	COG0752	glycyl-tRNA synthetase alpha subunit
GII83_12605	COG1381	Involved in DNA repair and RecF pathway recombination
GII83_12615	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII83_12620	COG0295	cytidine deaminase activity
GII83_12625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII83_12630	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII83_12635	COG1480	7TM receptor with intracellular HD hydrolase
GII83_12640	COG1702	phosphate starvation-inducible protein PhoH
GII83_12645	COG0561	phosphatase activity
GII83_12660	COG4864	UPF0365 protein
GII83_12665	COG1030	water channel activity
GII83_12670	COG1610	YqeY-like protein
GII83_12675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GII83_12680	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII83_12685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII83_12690	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII83_12695	COG2264	protein methyltransferase activity
GII83_12700	COG0484	heat shock protein binding
GII83_12705	COG0443	Heat shock 70 kDa protein
GII83_12710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII83_12715	COG1420	regulation of RNA biosynthetic process
GII83_12720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII83_12725	COG0481	GTPase activity
GII83_12735	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII83_12740	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII83_12745	COG0268	Binds directly to 16S ribosomal RNA
GII83_12750	COG1466	dna polymerase III delta subunit
GII83_12765	COG0658	competence protein
GII83_12765	COG2333	competence protein COMEC
GII83_12770	COG2131	deaminase
GII83_12775	COG1596	polysaccharide export
GII83_12775	COG1555	photosystem II stabilization
GII83_12780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII83_12785	COG2226	methyltransferase
GII83_12790	COG0799	negative regulation of ribosome biogenesis
GII83_12795	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII83_12800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII83_12805	COG1534	Rna-binding protein
GII83_12810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII83_12815	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII83_12820	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII83_12830	COG2755	lipolytic protein G-D-S-L family
GII83_12835	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII83_12835	COG3409	Peptidoglycan-binding domain 1 protein
GII83_12840	COG0398	Pfam SNARE associated Golgi protein
GII83_12855	COG3209	COG3209 Rhs family protein
GII83_12865	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII83_12880	COG2323	membrane
GII83_12885	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII83_12890	COG0730	response to heat
GII83_12895	COG0425	Belongs to the sulfur carrier protein TusA family
GII83_12900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII83_12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII83_12910	COG0425	Belongs to the sulfur carrier protein TusA family
GII83_12910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII83_12920	COG2210	Belongs to the sulfur carrier protein TusA family
GII83_12925	COG1937	Protein conserved in bacteria
GII83_12930	COG0662	Cupin 2, conserved barrel domain protein
GII83_12940	COG0457	Tetratricopeptide repeat
GII83_12950	COG5444	nuclease activity
GII83_12965	COG3409	Peptidoglycan-binding domain 1 protein
GII83_12965	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII83_12970	COG4824	toxin secretion phage lysis holin
GII83_13000	COG3778	Protein conserved in bacteria
GII83_13005	COG3299	homolog of phage Mu protein gp47
GII83_13010	COG3628	GPW Gp25 family protein
GII83_13020	COG4193	domain, Protein
GII83_13030	COG1652	LysM domain
GII83_13035	COG5280	Phage tail tape measure protein TP901
GII83_13035	COG3953	SLT domain
GII83_13095	COG4653	Phage capsid family
GII83_13100	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII83_13110	COG2369	cell adhesion
GII83_13115	COG5518	Phage portal protein
GII83_13120	COG1783	phage Terminase large subunit
GII83_13125	COG5484	DNA packaging
GII83_13135	COG1335	isochorismatase
GII83_13170	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GII83_13180	COG1484	DNA-dependent DNA replication
GII83_13185	COG3935	DnaD domain protein
GII83_13190	COG3723	Recombinational DNA repair protein, rece pathway
GII83_13195	COG5377	YqaJ viral recombinase family
GII83_13230	COG3620	sequence-specific DNA binding
GII83_13240	COG0563	adenylate kinase activity
GII83_13245	COG2856	Zn peptidase
GII83_13260	COG0642	Histidine kinase
GII83_13260	COG5002	protein histidine kinase activity
GII83_13265	COG0745	RESPONSE REGULATOR receiver
GII83_13270	COG2311	Membrane
GII83_13280	COG0454	-acetyltransferase
GII83_13285	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII83_13295	COG0730	response to heat
GII83_13300	COG0425	Belongs to the sulfur carrier protein TusA family
GII83_13305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII83_13305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII83_13315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII83_13315	COG0425	Belongs to the sulfur carrier protein TusA family
GII83_13325	COG1937	Protein conserved in bacteria
GII83_13330	COG0662	Cupin 2, conserved barrel domain protein
GII83_13340	COG4978	Transcriptional regulator
GII83_13340	COG0789	Transcriptional regulator
GII83_13345	COG2814	Major facilitator Superfamily
GII83_13350	COG0456	acetyltransferase
GII83_13355	COG1253	flavin adenine dinucleotide binding
GII83_13365	COG0697	spore germination
GII83_13370	COG0583	DNA-binding transcription factor activity
GII83_13375	COG2072	flavoprotein involved in K transport
GII83_13380	COG1230	cation diffusion facilitator family transporter
GII83_13385	COG1942	4-Oxalocrotonate Tautomerase
GII83_13390	COG0583	DNA-binding transcription factor activity
GII83_13400	COG1114	Component of the transport system for branched-chain amino acids
GII83_13405	COG1687	branched-chain amino acid
GII83_13410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII83_13415	COG1522	sequence-specific DNA binding
GII83_13425	COG2124	cytochrome p450
GII83_13430	COG1335	isochorismatase
GII83_13440	COG2318	DinB family
GII83_13450	COG2070	2-Nitropropane dioxygenase
GII83_13455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII83_13465	COG2186	Transcriptional regulator
GII83_13480	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_13485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII83_13490	COG3959	Transketolase, thiamine diphosphate binding domain
GII83_13500	COG0789	Transcriptional regulator
GII83_13500	COG4978	Transcriptional regulator
GII83_13505	COG2315	Protein conserved in bacteria
GII83_13515	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII83_13520	COG1595	DNA-templated transcription, initiation
GII83_13525	COG0667	Aldo Keto reductase
GII83_13530	COG2851	Citrate transporter
GII83_13535	COG0583	DNA-binding transcription factor activity
GII83_13540	COG2828	Protein conserved in bacteria
GII83_13545	COG3409	Peptidoglycan-binding domain 1 protein
GII83_13550	COG5566	PFAM Mor transcription activator
GII83_13555	COG0596	Alpha beta hydrolase
GII83_13560	COG4991	sh3 domain protein
GII83_13565	COG4991	sh3 domain protein
GII83_13575	COG0346	lactoylglutathione lyase activity
GII83_13585	COG5577	PFAM Coat F domain
GII83_13590	COG1063	alcohol dehydrogenase
GII83_13600	COG5577	PFAM Coat F domain
GII83_13605	COG0789	Transcriptional regulator
GII83_13615	COG1064	alcohol dehydrogenase
GII83_13620	COG0693	protein deglycase activity
GII83_13625	COG1621	beta-fructofuranosidase activity
GII83_13630	COG3716	PTS system mannose fructose sorbose family IID component
GII83_13635	COG3715	PTS system
GII83_13640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_13645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII83_13650	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII83_13650	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII83_13660	COG1113	amino acid transport
GII83_13665	COG1280	lysine exporter protein (LysE YggA)
GII83_13670	COG1378	Sugar-specific transcriptional regulator TrmB
GII83_13675	COG1595	DNA-templated transcription, initiation
GII83_13695	COG2124	cytochrome p450
GII83_13695	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII83_13700	COG1309	transcriptional regulator
GII83_13705	COG2226	methyltransferase
GII83_13720	COG2116	formate transmembrane transporter activity
GII83_13725	COG5609	conserved protein (DUF2294)
GII83_13730	COG3383	formate dehydrogenase (NAD+) activity
GII83_13735	COG2427	Protein of unknown function (DUF1641)
GII83_13745	COG0626	cystathionine gamma-synthase activity
GII83_13750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII83_13755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII83_13760	COG2226	methyltransferase
GII83_13775	COG0768	penicillin binding
GII83_13780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII83_13785	COG0572	uridine kinase
GII83_13805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII83_13810	COG3906	Belongs to the UPF0473 family
GII83_13815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII83_13820	COG4472	Bacterial protein of unknown function (DUF965)
GII83_13825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII83_13830	COG0628	permease
GII83_13835	COG1126	abc transporter atp-binding protein
GII83_13840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII83_13845	COG0765	amino acid transport
GII83_13850	COG0765	amino acid transport
GII83_13865	COG3881	PFAM PRC-barrel domain
GII83_13870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII83_13875	COG0457	Tetratricopeptide repeat
GII83_13880	COG0482	sulfurtransferase activity
GII83_13885	COG1104	cysteine desulfurase activity
GII83_13890	COG1959	2 iron, 2 sulfur cluster binding
GII83_13895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII83_13900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII83_13910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII83_13915	COG0124	histidyl-tRNA synthetase
GII83_13925	COG4991	sh3 domain protein
GII83_13925	COG3103	Sh3 type 3 domain protein
GII83_13925	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII83_13930	COG1490	D-aminoacyl-tRNA deacylase activity
GII83_13935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII83_13940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII83_13945	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII83_13945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII83_13950	COG5416	Lipopolysaccharide assembly protein A domain
GII83_13955	COG0490	domain, Protein
GII83_13960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII83_13960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII83_13970	COG2244	polysaccharide biosynthetic process
GII83_13975	COG2323	membrane
GII83_13985	COG1862	Preprotein translocase
GII83_13990	COG0343	queuine tRNA-ribosyltransferase activity
GII83_13995	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII83_14005	COG2255	four-way junction helicase activity
GII83_14010	COG0632	four-way junction helicase activity
GII83_14020	COG2814	Major facilitator Superfamily
GII83_14025	COG0673	inositol 2-dehydrogenase activity
GII83_14030	COG2112	serine threonine protein kinase
GII83_14050	COG1115	amino acid carrier protein
GII83_14055	COG0217	transcriptional regulatory protein
GII83_14065	COG1388	LysM domain
GII83_14070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII83_14075	COG0157	Belongs to the NadC ModD family
GII83_14080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII83_14085	COG1104	cysteine desulfurase activity
GII83_14090	COG1827	regulation of RNA biosynthetic process
GII83_14095	COG0077	Prephenate dehydratase
GII83_14100	COG4492	Belongs to the UPF0735 family
GII83_14105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII83_14110	COG3290	protein histidine kinase activity
GII83_14120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII83_14125	COG2868	ribosomal protein
GII83_14130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII83_14135	COG1994	Peptidase M50
GII83_14140	COG0739	heme binding
GII83_14145	COG2894	cell division
GII83_14150	COG0850	regulation of cytokinetic process
GII83_14155	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII83_14160	COG1792	Involved in formation and maintenance of cell shape
GII83_14165	COG1077	Cell shape determining protein MreB Mrl
GII83_14170	COG2003	Belongs to the UPF0758 family
GII83_14175	COG0424	maF-like protein
GII83_14185	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII83_14190	COG0285	dihydrofolate synthase activity
GII83_14195	COG0525	valine-tRNA ligase activity
GII83_14205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII83_14210	COG1388	LysM domain
GII83_14215	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII83_14220	COG0113	porphobilinogen synthase activity
GII83_14225	COG1587	Uroporphyrinogen-III synthase
GII83_14230	COG0181	hydroxymethylbilane synthase activity
GII83_14235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII83_14240	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII83_14250	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII83_14255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII83_14260	COG0470	DNA polymerase III
GII83_14260	COG1067	ATP-dependent peptidase activity
GII83_14265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII83_14270	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII83_14275	COG0457	Tetratricopeptide repeat
GII83_14275	COG1477	protein flavinylation
GII83_14280	COG0066	3-isopropylmalate dehydratase activity
GII83_14285	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII83_14290	COG0473	3-isopropylmalate dehydrogenase activity
GII83_14295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII83_14300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII83_14305	COG0440	acetolactate synthase activity
GII83_14310	COG0028	Belongs to the TPP enzyme family
GII83_14320	COG0454	-acetyltransferase
GII83_14325	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII83_14335	COG0622	Phosphoesterase
GII83_14340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII83_14345	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII83_14350	COG5401	PFAM Sporulation and spore germination
GII83_14355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII83_14360	COG1846	Transcriptional regulator
GII83_14365	COG2197	response regulator
GII83_14370	COG0824	Thioesterase
GII83_14375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII83_14380	COG1053	succinate dehydrogenase
GII83_14385	COG2009	succinate dehydrogenase
GII83_14390	COG1719	4-vinyl reductase, 4VR
GII83_14395	COG0527	aspartate kinase activity
GII83_14400	COG0322	excinuclease ABC activity
GII83_14405	COG3118	belongs to the thioredoxin family
GII83_14410	COG3534	alpha-L-arabinofuranosidase
GII83_14415	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII83_14420	COG2086	electron transfer activity
GII83_14425	COG1024	Enoyl-CoA hydratase
GII83_14430	COG1309	transcriptional regulator
GII83_14435	COG0318	PFAM AMP-dependent synthetase and ligase
GII83_14440	COG3766	membrane
GII83_14445	COG1193	negative regulation of DNA recombination
GII83_14450	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII83_14450	COG1796	DNA polymerase
GII83_14455	COG1286	toxin biosynthetic process
GII83_14460	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII83_14465	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII83_14470	COG0072	phenylalanine-tRNA ligase activity
GII83_14470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII83_14475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII83_14485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII83_14495	COG3835	regulator
GII83_14500	COG0277	FAD linked oxidase domain protein
GII83_14505	COG0247	lactate metabolic process
GII83_14520	COG1966	Carbon starvation protein
GII83_14525	COG3534	alpha-L-arabinofuranosidase
GII83_14530	COG0395	ABC-type sugar transport system, permease component
GII83_14535	COG1175	transmembrane transport
GII83_14540	COG1653	transport
GII83_14545	COG0371	Dehydrogenase
GII83_14550	COG0647	UMP catabolic process
GII83_14555	COG0235	Class ii aldolase
GII83_14560	COG1069	ribulokinase activity
GII83_14565	COG2160	L-arabinose isomerase activity
GII83_14570	COG3507	Belongs to the glycosyl hydrolase 43 family
GII83_14575	COG1363	Peptidase, m42
GII83_14585	COG3326	Membrane
GII83_14590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII83_14595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII83_14600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII83_14610	COG1346	cytolysis
GII83_14615	COG1380	Effector of murein hydrolase LrgA
GII83_14620	COG3279	Response regulator of the LytR AlgR family
GII83_14625	COG3275	phosphorelay sensor kinase activity
GII83_14635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII83_14645	COG0398	Pfam SNARE associated Golgi protein
GII83_14650	COG1484	DNA-dependent DNA replication
GII83_14655	COG3611	Membrane attachment protein
GII83_14660	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII83_14665	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII83_14670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII83_14675	COG1733	regulation of RNA biosynthetic process
GII83_14680	COG2814	Major facilitator Superfamily
GII83_14685	COG0656	L-ascorbic acid biosynthetic process
GII83_14690	COG0237	dephospho-CoA kinase activity
GII83_14695	COG1971	Probably functions as a manganese efflux pump
GII83_14700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII83_14705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII83_14705	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII83_14710	COG5002	protein histidine kinase activity
GII83_14715	COG0745	RESPONSE REGULATOR receiver
GII83_14720	COG0039	L-malate dehydrogenase activity
GII83_14725	COG0538	isocitrate dehydrogenase activity
GII83_14730	COG0372	Belongs to the citrate synthase family
GII83_14735	COG2707	UPF0756 membrane protein
GII83_14740	COG0628	permease
GII83_14745	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII83_14750	COG0469	pyruvate kinase activity
GII83_14755	COG0205	6-phosphofructokinase activity
GII83_14760	COG0825	malonyl-CoA metabolic process
GII83_14765	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII83_14770	COG0281	malic enzyme
GII83_14775	COG0587	DNA-directed DNA polymerase activity
GII83_14795	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII83_14805	COG4109	DRTGG domain
GII83_14810	COG0730	response to heat
GII83_14815	COG1473	amidohydrolase
GII83_14820	COG0196	riboflavin kinase activity
GII83_14825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII83_14830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII83_14835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII83_14840	COG1126	abc transporter atp-binding protein
GII83_14845	COG0765	amino acid transport
GII83_14850	COG0765	amino acid transport
GII83_14855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII83_14860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII83_14865	COG0454	-acetyltransferase
GII83_14870	COG0583	DNA-binding transcription factor activity
GII83_14875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII83_14880	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_14890	COG0165	Argininosuccinate lyase
GII83_14895	COG0137	argininosuccinate synthase activity
GII83_14900	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII83_14905	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII83_14915	COG0827	DNA restriction-modification system
GII83_14920	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII83_14925	COG3874	Sporulation protein YtfJ
GII83_14935	COG1714	RDD family
GII83_14940	COG0616	signal peptide processing
GII83_14945	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII83_14950	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII83_14955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII83_14965	COG0301	tRNA thio-modification
GII83_14970	COG1104	cysteine desulfurase activity
GII83_14975	COG1114	Component of the transport system for branched-chain amino acids
GII83_14980	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII83_14985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII83_14990	COG1309	transcriptional regulator
GII83_14995	COG1956	GAF domain-containing protein
GII83_15000	COG2199	diguanylate cyclase activity
GII83_15000	COG2203	Gaf domain
GII83_15010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII83_15015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII83_15020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII83_15025	COG0454	-acetyltransferase
GII83_15030	COG0517	IMP dehydrogenase activity
GII83_15035	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII83_15040	COG1360	Flagellar Motor Protein
GII83_15045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII83_15050	COG1609	Transcriptional regulator
GII83_15055	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII83_15055	COG1605	Chorismate mutase
GII83_15060	COG3118	belongs to the thioredoxin family
GII83_15065	COG4980	gas vesicle protein
GII83_15070	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII83_15075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII83_15080	COG1674	ftsk spoiiie
GII83_15085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII83_15090	COG4848	Belongs to the UPF0354 family
GII83_15095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII83_15110	COG1363	Peptidase, m42
GII83_15115	COG5584	Small secreted protein
GII83_15120	COG0281	malic enzyme
GII83_15125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII83_15130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII83_15140	COG0510	thiamine kinase activity
GII83_15145	COG1523	belongs to the glycosyl hydrolase 13 family
GII83_15150	COG1597	lipid kinase activity
GII83_15160	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII83_15165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII83_15170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII83_15175	COG2252	PERMEase
GII83_15180	COG4473	ABC transporter
GII83_15185	COG1131	(ABC) transporter
GII83_15190	COG1349	DNA-binding transcription factor activity
GII83_15195	COG1187	pseudouridine synthase activity
GII83_15200	COG2244	polysaccharide biosynthetic process
GII83_15205	COG2081	HI0933 family
GII83_15210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII83_15220	COG5578	integral membrane protein
GII83_15225	COG0673	inositol 2-dehydrogenase activity
GII83_15230	COG1653	transport
GII83_15235	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII83_15240	COG4209	transmembrane transport
GII83_15245	COG2207	Transcriptional regulator
GII83_15250	COG1653	transport
GII83_15255	COG0395	ABC-type sugar transport system, permease component
GII83_15260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII83_15265	COG2124	cytochrome p450
GII83_15270	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII83_15280	COG0156	8-amino-7-oxononanoate synthase activity
GII83_15285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII83_15295	COG1073	alpha beta
GII83_15320	COG1486	melibiose metabolic process
GII83_15325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII83_15330	COG0495	leucyl-tRNA aminoacylation
GII83_15340	COG2202	Pas domain
GII83_15340	COG1366	Belongs to the anti-sigma-factor antagonist family
GII83_15345	COG2814	Major facilitator Superfamily
GII83_15350	COG2433	Pfam Transposase IS66
GII83_15355	COG0577	efflux transmembrane transporter activity
GII83_15360	COG1136	(ABC) transporter
GII83_15365	COG2205	protein histidine kinase activity
GII83_15370	COG0745	RESPONSE REGULATOR receiver
GII83_15375	COG0577	efflux transmembrane transporter activity
GII83_15380	COG1136	(ABC) transporter
GII83_15395	COG1131	(ABC) transporter
GII83_15400	COG1725	Transcriptional regulator
GII83_15415	COG1242	4 iron, 4 sulfur cluster binding
GII83_15420	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII83_15430	COG2267	carboxylic ester hydrolase activity
GII83_15435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII83_15440	COG1113	amino acid transport
GII83_15445	COG0367	asparagine synthase
GII83_15450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII83_15455	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII83_15465	COG1506	peptidase
GII83_15470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII83_15475	COG1116	anion transmembrane transporter activity
GII83_15480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII83_15485	COG0494	nUDIX hydrolase
GII83_15490	COG4824	toxin secretion phage lysis holin
GII83_15495	COG0783	Belongs to the Dps family
GII83_15510	COG1854	S-ribosylhomocysteine lyase activity
GII83_15515	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII83_15520	COG0288	reversible hydration of carbon dioxide
GII83_15525	COG0254	rRNA binding
GII83_15530	COG1271	oxidase subunit
GII83_15535	COG1294	oxidase, subunit
GII83_15545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII83_15550	COG1321	iron dependent repressor
GII83_15550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII83_15555	COG1121	(ABC) transporter
GII83_15560	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII83_15565	COG4948	Mandelate Racemase Muconate Lactonizing
GII83_15570	COG0318	PFAM AMP-dependent synthetase and ligase
GII83_15575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII83_15580	COG0596	Alpha beta hydrolase
GII83_15585	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII83_15590	COG1169	isochorismate synthase
GII83_15595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII83_15600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII83_15605	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII83_15610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII83_15615	COG0438	transferase activity, transferring glycosyl groups
GII83_15625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII83_15630	COG0438	transferase activity, transferring glycosyl groups
GII83_15635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII83_15640	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GII83_15645	COG0058	SHG alpha-glucan phosphorylase activity
GII83_15650	COG0297	glycogen (starch) synthase activity
GII83_15655	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII83_15660	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII83_15665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII83_15790	COG3859	Proton-coupled thiamine transporter YuaJ
GII83_15795	COG1247	-acetyltransferase
GII83_15800	COG2268	Band 7 protein
GII83_15805	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII83_15810	COG2318	DinB family
GII83_15820	COG1454	alcohol dehydrogenase
GII83_15830	COG1510	regulation of RNA biosynthetic process
GII83_15840	COG0569	domain protein
GII83_15845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII83_15850	COG4682	membrane
GII83_15855	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII83_15860	COG0477	Major facilitator Superfamily
GII83_15865	COG5553	Cysteine dioxygenase type I
GII83_15875	COG1968	undecaprenyl-diphosphatase activity
GII83_15880	COG0628	permease
GII83_15885	COG0673	inositol 2-dehydrogenase activity
GII83_15890	COG4806	L-rhamnose isomerase
GII83_15895	COG3254	rhamnose metabolic process
GII83_15900	COG1070	Carbohydrate kinase
GII83_15905	COG1349	DNA-binding transcription factor activity
GII83_15910	COG3347	Dehydrogenase
GII83_15910	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_15915	COG0840	transmembrane signaling receptor activity
GII83_15920	COG0840	transmembrane signaling receptor activity
GII83_15925	COG0840	transmembrane signaling receptor activity
GII83_15930	COG0840	transmembrane signaling receptor activity
GII83_15945	COG0432	Pfam Uncharacterised protein family UPF0047
GII83_15955	COG0366	Alpha amylase catalytic
GII83_15960	COG1253	flavin adenine dinucleotide binding
GII83_15965	COG2738	Putative neutral zinc metallopeptidase
GII83_15980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII83_15995	COG0166	Belongs to the GPI family
GII83_16000	COG1979	alcohol dehydrogenase
GII83_16005	COG1979	alcohol dehydrogenase
GII83_16010	COG2155	Conserved Protein
GII83_16015	COG1098	S1 RNA binding domain
GII83_16020	COG0436	Aminotransferase
GII83_16025	COG1522	sequence-specific DNA binding
GII83_16030	COG2267	carboxylic ester hydrolase activity
GII83_16040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII83_16045	COG2205	protein histidine kinase activity
GII83_16055	COG5018	Exonuclease
GII83_16065	COG2814	Major facilitator Superfamily
GII83_16070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII83_16075	COG3011	Protein conserved in bacteria
GII83_16085	COG3290	protein histidine kinase activity
GII83_16090	COG4565	transcriptional regulatory protein
GII83_16115	COG3493	citrate carrier protein
GII83_16125	COG2111	Na H antiporter
GII83_16125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII83_16130	COG2111	Na H antiporter
GII83_16135	COG1006	Multisubunit Na H antiporter MnhC subunit
GII83_16140	COG0651	ATP synthesis coupled electron transport
GII83_16145	COG1863	multisubunit Na H antiporter MnhE subunit
GII83_16150	COG2212	antiporter activity
GII83_16155	COG1320	monovalent cation:proton antiporter activity
GII83_16160	COG2050	protein possibly involved in aromatic compounds catabolism
GII83_16165	COG2197	response regulator
GII83_16170	COG4585	Histidine kinase
GII83_16180	COG0142	geranyltranstransferase activity
GII83_16195	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII83_16200	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII83_16205	COG1335	isochorismatase
GII83_16210	COG5506	Protein of unknown function (DUF1694)
GII83_16225	COG0628	permease
GII83_16240	COG1418	mRNA catabolic process
GII83_16245	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_16255	COG1511	domain protein
GII83_16260	COG1674	ftsk spoiiie
GII83_16260	COG0433	COG0433 Predicted ATPase
GII83_16265	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII83_16270	COG5417	Belongs to the EsaB family
GII83_16275	COG4842	Belongs to the WXG100 family
GII83_16280	COG2508	Transcriptional regulator
GII83_16280	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII83_16285	COG0686	Belongs to the AlaDH PNT family
GII83_16290	COG5634	Uncharacterized conserved protein (DUF2278)
GII83_16295	COG3251	PFAM MbtH domain protein
GII83_16300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_16305	COG1535	isochorismatase
GII83_16305	COG3433	isochorismatase activity
GII83_16310	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII83_16315	COG1169	isochorismate synthase
GII83_16320	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_16325	COG2819	hydrolase of the alpha beta superfamily
GII83_16330	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII83_16335	COG1268	BioY protein
GII83_16340	COG2056	Na+-H+ antiporter family
GII83_16345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII83_16350	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII83_16355	COG3584	3D domain protein
GII83_16370	COG1252	NADH dehydrogenase
GII83_16375	COG0492	ferredoxin-NADP+ reductase activity
GII83_16385	COG0516	GMP reductase activity
GII83_16390	COG2808	Putative FMN-binding domain
GII83_16395	COG0456	acetyltransferase
GII83_16400	COG0316	Belongs to the HesB IscA family
GII83_16405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII83_16410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII83_16415	COG4844	belongs to the
GII83_16420	COG1252	NADH dehydrogenase
GII83_16425	COG4837	Protein of unknown function (DUF1462)
GII83_16430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII83_16435	COG0823	Involved in the tonB-independent uptake of proteins
GII83_16435	COG1506	peptidase
GII83_16435	COG4946	Tricorn protease homolog
GII83_16440	COG0083	homoserine kinase activity
GII83_16445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII83_16450	COG0460	homoserine dehydrogenase
GII83_16455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII83_16460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII83_16465	COG0647	UMP catabolic process
GII83_16470	COG2445	Protein of unknown function DUF86
GII83_16475	COG4470	Protein conserved in bacteria
GII83_16485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII83_16490	COG0739	heme binding
GII83_16500	COG3377	Domain of unknown function (DUF1805)
GII83_16505	COG0737	Belongs to the 5'-nucleotidase family
GII83_16510	COG0730	response to heat
GII83_16515	COG1801	Protein of unknown function DUF72
GII83_16525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII83_16530	COG2508	Transcriptional regulator
GII83_16535	COG2233	PERMEase
GII83_16540	COG2233	PERMEase
GII83_16545	COG3195	allantoin biosynthetic process
GII83_16545	COG3648	Uricase
GII83_16550	COG2351	hydroxyisourate hydrolase activity
GII83_16560	COG2080	2 iron, 2 sulfur cluster binding
GII83_16565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII83_16570	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII83_16575	COG2068	MobA-Related Protein
GII83_16580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII83_16585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII83_16590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII83_16600	COG2356	endonuclease I
GII83_16605	COG3842	ATPase activity
GII83_16610	COG2188	Transcriptional regulator
GII83_16615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII83_16620	COG0395	ABC-type sugar transport system, permease component
GII83_16625	COG1175	transmembrane transport
GII83_16630	COG1653	transport
GII83_16635	COG2222	sugar isomerase
GII83_16640	COG0322	excinuclease ABC activity
GII83_16645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII83_16660	COG0719	Fe-S assembly protein
GII83_16665	COG0822	iron-sulfur transferase activity
GII83_16670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII83_16675	COG0719	Fe-S assembly protein
GII83_16680	COG0396	ATPase activity
GII83_16690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII83_16695	COG1464	Belongs to the NlpA lipoprotein family
GII83_16700	COG2011	ABC-type metal ion transport system permease component
GII83_16705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII83_16715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII83_16720	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII83_16730	COG0509	glycine decarboxylation via glycine cleavage system
GII83_16735	COG1393	Belongs to the ArsC family
GII83_16740	COG1960	acyl-CoA dehydrogenase activity
GII83_16745	COG0183	Belongs to the thiolase family
GII83_16750	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII83_16750	COG1024	Enoyl-CoA hydratase
GII83_16760	COG0506	proline dehydrogenase activity
GII83_16770	COG5577	PFAM Coat F domain
GII83_16775	COG1846	Transcriptional regulator
GII83_16780	COG0477	Major facilitator Superfamily
GII83_16785	COG1942	4-Oxalocrotonate Tautomerase
GII83_16790	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_16795	COG0583	DNA-binding transcription factor activity
GII83_16805	COG1120	ATPase activity
GII83_16820	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_16825	COG0783	Belongs to the Dps family
GII83_16830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII83_16835	COG0745	RESPONSE REGULATOR receiver
GII83_16840	COG2205	protein histidine kinase activity
GII83_16840	COG2770	Histidine kinase
GII83_16850	COG1309	transcriptional regulator
GII83_16855	COG0114	fumarate hydratase activity
GII83_16865	COG0697	spore germination
GII83_16870	COG0814	amino acid
GII83_16880	COG2197	response regulator
GII83_16885	COG4585	Histidine kinase
GII83_16890	COG4758	membrane
GII83_16895	COG3595	metallopeptidase activity
GII83_16900	COG1842	Phage shock protein A
GII83_16905	COG4758	membrane
GII83_16910	COG2814	Major facilitator Superfamily
GII83_16915	COG2096	Adenosyltransferase
GII83_16920	COG1120	ATPase activity
GII83_16925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII83_16930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII83_16935	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_16940	COG3386	PFAM SMP-30 Gluconolaconase
GII83_16945	COG2205	protein histidine kinase activity
GII83_16950	COG0745	RESPONSE REGULATOR receiver
GII83_16960	COG1191	sigma factor activity
GII83_16970	COG2140	Oxalate decarboxylase
GII83_16980	COG0577	efflux transmembrane transporter activity
GII83_16985	COG1136	(ABC) transporter
GII83_16990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII83_16995	COG1120	ATPase activity
GII83_17000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII83_17005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII83_17010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII83_17015	COG0531	amino acid
GII83_17025	COG1988	membrane-bound metal-dependent
GII83_17030	COG1368	sulfuric ester hydrolase activity
GII83_17035	COG1910	domain protein
GII83_17040	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII83_17045	COG4149	molybdate abc transporter
GII83_17050	COG0656	L-ascorbic acid biosynthetic process
GII83_17060	COG0025	NhaP-type Na H and K H
GII83_17065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII83_17070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII83_17075	COG3973	AAA domain
GII83_17085	COG2860	membrane
GII83_17090	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII83_17095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII83_17100	COG2217	Heavy metal translocating P-type atpase
GII83_17105	COG2217	Heavy metal translocating P-type atpase
GII83_17110	COG2608	mercury ion transmembrane transporter activity
GII83_17115	COG1937	Protein conserved in bacteria
GII83_17120	COG0673	inositol 2-dehydrogenase activity
GII83_17125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII83_17130	COG1289	transmembrane transporter activity
GII83_17140	COG2076	Multidrug Resistance protein
GII83_17145	COG1309	transcriptional regulator
GII83_17150	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_17160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII83_17165	COG0557	exoribonuclease II activity
GII83_17170	COG1647	Serine aminopeptidase, S33
GII83_17175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII83_17180	COG0596	Alpha beta hydrolase
GII83_17185	COG1476	TRANSCRIPTIONal
GII83_17190	COG1396	sequence-specific DNA binding
GII83_17195	COG1396	sequence-specific DNA binding
GII83_17200	COG1733	regulation of RNA biosynthetic process
GII83_17205	COG0840	transmembrane signaling receptor activity
GII83_17210	COG1174	glycine betaine transport
GII83_17215	COG1732	Glycine betaine
GII83_17220	COG1174	glycine betaine transport
GII83_17225	COG1125	glycine betaine transport
GII83_17225	COG0517	IMP dehydrogenase activity
GII83_17230	COG1510	regulation of RNA biosynthetic process
GII83_17235	COG1174	glycine betaine transport
GII83_17240	COG1732	Glycine betaine
GII83_17245	COG1174	glycine betaine transport
GII83_17250	COG1125	glycine betaine transport
GII83_17250	COG0517	IMP dehydrogenase activity
GII83_17255	COG1510	regulation of RNA biosynthetic process
GII83_17260	COG2095	MarC family integral membrane protein
GII83_17270	COG3064	Membrane
GII83_17275	COG4640	response to antibiotic
GII83_17280	COG0456	acetyltransferase
GII83_17285	COG0148	phosphopyruvate hydratase activity
GII83_17290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII83_17295	COG0149	triose-phosphate isomerase activity
GII83_17300	COG0126	phosphoglycerate kinase activity
GII83_17305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII83_17310	COG2390	Transcriptional regulator
GII83_17315	COG2814	Major facilitator Superfamily
GII83_17320	COG1609	Transcriptional regulator
GII83_17325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII83_17335	COG0583	DNA-binding transcription factor activity
GII83_17340	COG0697	spore germination
GII83_17345	COG1113	amino acid transport
GII83_17350	COG3858	chitin binding
GII83_17355	COG1556	Lactate utilization protein
GII83_17360	COG1139	Iron-sulfur cluster binding protein
GII83_17365	COG0247	lactate metabolic process
GII83_17370	COG2197	response regulator
GII83_17375	COG4585	Histidine kinase
GII83_17380	COG0842	Transport permease protein
GII83_17385	COG1131	(ABC) transporter
GII83_17390	COG0596	Alpha beta hydrolase
GII83_17395	COG2208	phosphoserine phosphatase activity
GII83_17400	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII83_17405	COG1874	Beta-galactosidase
GII83_17410	COG3833	ABC-type maltose transport systems, permease component
GII83_17415	COG1175	transmembrane transport
GII83_17420	COG2182	Extracellular solute-binding protein
GII83_17425	COG1609	Transcriptional regulator
GII83_17430	COG2186	Transcriptional regulator
GII83_17435	COG1620	l-lactate permease
GII83_17440	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII83_17450	COG5039	Polysaccharide pyruvyl transferase
GII83_17455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII83_17460	COG0110	maltose O-acetyltransferase activity
GII83_17465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII83_17470	COG2244	polysaccharide biosynthetic process
GII83_17475	COG1216	Glycosyl transferase, family 2
GII83_17480	COG5039	Polysaccharide pyruvyl transferase
GII83_17485	COG1216	Glycosyl transferase, family 2
GII83_17495	COG0438	transferase activity, transferring glycosyl groups
GII83_17500	COG1215	transferase activity, transferring glycosyl groups
GII83_17505	COG0438	transferase activity, transferring glycosyl groups
GII83_17510	COG1086	Polysaccharide biosynthesis protein
GII83_17515	COG0489	protein tyrosine kinase activity
GII83_17520	COG3944	biosynthesis protein
GII83_17525	COG1396	sequence-specific DNA binding
GII83_17530	COG2272	Belongs to the type-B carboxylesterase lipase family
GII83_17540	COG3479	Phenolic acid decarboxylase
GII83_17550	COG1794	racemase activity, acting on amino acids and derivatives
GII83_17555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII83_17560	COG1621	beta-fructofuranosidase activity
GII83_17565	COG1621	beta-fructofuranosidase activity
GII83_17570	COG0531	amino acid
GII83_17575	COG1309	transcriptional regulator
GII83_17580	COG2076	Multidrug Resistance protein
GII83_17585	COG2076	Multidrug Resistance protein
GII83_17595	COG0277	FAD linked oxidase domain protein
GII83_17600	COG3621	Patatin-like phospholipase
GII83_17610	COG0740	serine-type endopeptidase activity
GII83_17615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII83_17620	COG0366	Alpha amylase catalytic
GII83_17625	COG1554	hydrolase, family 65, central catalytic
GII83_17630	COG5521	maltodextrose utilization protein MalA
GII83_17635	COG3833	ABC-type maltose transport systems, permease component
GII83_17640	COG1175	transmembrane transport
GII83_17645	COG2182	Extracellular solute-binding protein
GII83_17650	COG0366	Alpha amylase catalytic
GII83_17655	COG1609	Transcriptional regulator
GII83_17660	COG1611	Belongs to the LOG family
GII83_17665	COG1694	Mazg nucleotide pyrophosphohydrolase
GII83_17670	COG0659	secondary active sulfate transmembrane transporter activity
GII83_17675	COG0288	reversible hydration of carbon dioxide
GII83_17680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII83_17685	COG0577	efflux transmembrane transporter activity
GII83_17690	COG1136	(ABC) transporter
GII83_17695	COG5002	protein histidine kinase activity
GII83_17700	COG0745	RESPONSE REGULATOR receiver
GII83_17710	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII83_17715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII83_17720	COG1481	regulation of sporulation
GII83_17725	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII83_17730	COG1660	Displays ATPase and GTPase activities
GII83_17735	COG1051	belongs to the nudix hydrolase family
GII83_17740	COG0492	ferredoxin-NADP+ reductase activity
GII83_17745	COG0791	NLP P60 protein
GII83_17745	COG3883	PFAM NLP P60 protein
GII83_17750	COG0457	Tetratricopeptide repeat
GII83_17755	COG1132	(ABC) transporter
GII83_17775	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII83_17775	COG0140	phosphoribosyl-ATP diphosphatase activity
GII83_17780	COG0107	imidazoleglycerol-phosphate synthase activity
GII83_17785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII83_17790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII83_17795	COG0131	Imidazoleglycerol-phosphate dehydratase
GII83_17800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII83_17805	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII83_17810	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII83_17815	COG4990	cell redox homeostasis
GII83_17820	COG5297	Belongs to the glycosyl hydrolase family 6
GII83_17825	COG0110	maltose O-acetyltransferase activity
GII83_17830	COG0546	phosphoglycolate phosphatase activity
GII83_17835	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII83_17840	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII83_17845	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII83_17850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII83_17855	COG0363	glucosamine-6-phosphate deaminase activity
GII83_17865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII83_17870	COG1846	Transcriptional regulator
GII83_17875	COG2124	cytochrome p450
GII83_17885	COG1846	Transcriptional regulator
GII83_17890	COG2814	Major facilitator Superfamily
GII83_17895	COG1950	PFAM Membrane protein of
GII83_17900	COG1983	PspC domain protein
GII83_17905	COG3595	metallopeptidase activity
GII83_17920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII83_17925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII83_17930	COG0556	nucleotide-excision repair
GII83_17935	COG4897	Protein conserved in bacteria
GII83_17940	COG0574	Belongs to the PEP-utilizing enzyme family
GII83_17940	COG3848	Pyruvate phosphate dikinase
GII83_17945	COG1309	transcriptional regulator
GII83_17950	COG2814	Major facilitator Superfamily
GII83_17955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII83_17965	COG3409	Peptidoglycan-binding domain 1 protein
GII83_17965	COG0793	Belongs to the peptidase S41A family
GII83_17970	COG2177	Part of the ABC transporter FtsEX involved in
GII83_17975	COG2884	Cell division ATP-binding protein ftsE
GII83_17980	COG2010	Cytochrome c
GII83_17985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII83_17995	COG0653	protein targeting
GII83_18000	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII83_18015	COG1516	flagellar protein fliS
GII83_18020	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII83_18025	COG1334	flagellar protein FlaG
GII83_18030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII83_18035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII83_18040	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII83_18050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII83_18055	COG1256	bacterial-type flagellum assembly
GII83_18055	COG4786	Flagellar basal body rod
GII83_18060	COG3418	PFAM FlgN family protein
GII83_18065	COG2747	anti-sigma28 factor FlgM
GII83_18075	COG1040	competence protein
GII83_18085	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII83_18090	COG1307	EDD domain protein, DegV family
GII83_18095	COG2197	response regulator
GII83_18100	COG4585	Histidine kinase
GII83_18105	COG1739	Uncharacterized protein family UPF0029
GII83_18110	COG1316	TRANSCRIPTIONal
GII83_18115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII83_18120	COG0438	transferase activity, transferring glycosyl groups
GII83_18125	COG1215	transferase activity, transferring glycosyl groups
GII83_18130	COG3206	protein involved in exopolysaccharide biosynthesis
GII83_18135	COG3307	-O-antigen
GII83_18140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII83_18145	COG0297	glycogen (starch) synthase activity
GII83_18145	COG0438	transferase activity, transferring glycosyl groups
GII83_18150	COG2244	polysaccharide biosynthetic process
GII83_18165	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII83_18165	COG2247	cell wall binding repeat
GII83_18170	COG2385	sporulation resulting in formation of a cellular spore
GII83_18170	COG2247	cell wall binding repeat
GII83_18180	COG1316	TRANSCRIPTIONal
GII83_18185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII83_18205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII83_18210	COG1134	teichoic acid transport
GII83_18215	COG1682	transport, permease protein
GII83_18230	COG1215	transferase activity, transferring glycosyl groups
GII83_18230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII83_18235	COG0463	Glycosyl transferase, family 2
GII83_18280	COG4193	domain, Protein
GII83_18285	COG1482	cell wall glycoprotein biosynthetic process
GII83_18290	COG0697	spore germination
GII83_18295	COG0814	amino acid
GII83_18305	COG2814	Major facilitator Superfamily
GII83_18310	COG1316	TRANSCRIPTIONal
GII83_18315	COG0561	phosphatase activity
GII83_18320	COG0791	NLP P60 protein
GII83_18330	COG2843	Capsule synthesis protein
GII83_18340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII83_18345	COG1609	Transcriptional regulator
GII83_18350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII83_18355	COG1869	D-ribose catabolic process
GII83_18360	COG1129	ABC transporter
GII83_18365	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII83_18370	COG1879	ABC-type sugar transport system periplasmic component
GII83_18375	COG3103	Sh3 type 3 domain protein
GII83_18385	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII83_18390	COG3527	Alpha-acetolactate decarboxylase
GII83_18395	COG0028	Belongs to the TPP enzyme family
GII83_18400	COG0583	DNA-binding transcription factor activity
GII83_18405	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII83_18420	COG5337	Spore coat protein CotH
GII83_18430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII83_18440	COG0405	Gamma-glutamyltransferase
GII83_18445	COG1522	sequence-specific DNA binding
GII83_18450	COG2059	Chromate
GII83_18455	COG2059	Chromate
GII83_18465	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII83_18470	COG0583	DNA-binding transcription factor activity
GII83_18500	COG5444	nuclease activity
GII83_18520	COG3878	Protein conserved in bacteria
GII83_18525	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII83_18530	COG4464	protein tyrosine phosphatase activity
GII83_18535	COG0489	protein tyrosine kinase activity
GII83_18540	COG3944	biosynthesis protein
GII83_18550	COG4715	Zinc finger, swim domain protein
GII83_18555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII83_18560	COG0561	phosphatase activity
GII83_18565	COG1349	DNA-binding transcription factor activity
GII83_18570	COG0629	single-stranded DNA binding
GII83_18585	COG3764	Sortase (surface protein transpeptidase)
GII83_18600	COG1970	mechanosensitive ion channel activity
GII83_18605	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII83_18610	COG0457	Tetratricopeptide repeat
GII83_18615	COG4786	Flagellar basal body rod
GII83_18620	COG4786	Flagellar basal body rod
GII83_18625	COG1077	Cell shape determining protein MreB Mrl
GII83_18630	COG1609	Transcriptional regulator
GII83_18640	COG1846	Transcriptional regulator
GII83_18645	COG2814	Major facilitator Superfamily
GII83_18650	COG3420	alginic acid biosynthetic process
GII83_18655	COG1953	Uracil, thiamine, allantoin
GII83_18660	COG0477	Major facilitator Superfamily
GII83_18665	COG1335	isochorismatase
GII83_18675	COG0004	ammonium transporteR
GII83_18680	COG0347	Belongs to the P(II) protein family
GII83_18685	COG0671	phosphoesterase, PA-phosphatase related
GII83_18695	COG0739	heme binding
GII83_18700	COG1247	-acetyltransferase
GII83_18720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII83_18725	COG0789	Transcriptional regulator
GII83_18735	COG2910	NAD(P)H-binding
GII83_18740	COG1959	2 iron, 2 sulfur cluster binding
GII83_18745	COG0804	urea catabolic process
GII83_18750	COG0832	Belongs to the urease beta subunit family
GII83_18755	COG0831	urea catabolic process
GII83_18770	COG3237	CsbD-like
GII83_18775	COG1994	Peptidase M50
GII83_18780	COG0457	Tetratricopeptide repeat
GII83_18785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII83_18790	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII83_18800	COG2304	oxidoreductase activity
GII83_18810	COG2304	oxidoreductase activity
GII83_18815	COG2385	sporulation resulting in formation of a cellular spore
GII83_18820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII83_18830	COG4836	Membrane
GII83_18840	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII83_18845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII83_18850	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII83_18855	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII83_18860	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII83_18865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII83_18870	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII83_18875	COG0356	it plays a direct role in the translocation of protons across the membrane
GII83_18885	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII83_18890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII83_18895	COG4475	Protein of unknown function (DUF436)
GII83_18900	COG0698	ribose 5-phosphate isomerase
GII83_18905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII83_18910	COG1971	Probably functions as a manganese efflux pump
GII83_18915	COG0009	L-threonylcarbamoyladenylate synthase
GII83_18920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII83_18940	COG2890	protein-(glutamine-N5) methyltransferase activity
GII83_18945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII83_18950	COG0346	lactoylglutathione lyase activity
GII83_18955	COG0789	Transcriptional regulator
GII83_18960	COG0679	Auxin Efflux Carrier
GII83_18965	COG0281	malic enzyme
GII83_18970	COG1435	thymidine kinase activity
GII83_18975	COG0254	rRNA binding
GII83_18980	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII83_18990	COG1494	fructose-1,6-bisphosphatase
GII83_18995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII83_19000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII83_19005	COG0191	fructose-bisphosphate aldolase activity
GII83_19010	COG2204	response regulator
GII83_19015	COG4821	SIS domain
GII83_19020	COG0504	CTP synthase activity
GII83_19025	COG3343	RNA polymerase activity
GII83_19030	COG1960	acyl-CoA dehydrogenase activity
GII83_19035	COG2181	nitrate reductase activity
GII83_19035	COG0247	lactate metabolic process
GII83_19040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII83_19045	COG4294	response to UV
GII83_19055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII83_19060	COG1132	(ABC) transporter
GII83_19065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII83_19075	COG2181	nitrate reductase activity
GII83_19080	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GII83_19085	COG1140	nitrate reductase beta subunit
GII83_19090	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII83_19095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII83_19105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII83_19110	COG2223	nitrite transmembrane transporter activity
GII83_19115	COG0018	arginyl-trna synthetase
GII83_19120	COG4506	Protein conserved in bacteria
GII83_19135	COG0535	radical SAM domain protein
GII83_19145	COG1131	(ABC) transporter
GII83_19150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII83_19155	COG0612	Peptidase, M16
GII83_19160	COG0612	Peptidase, M16
GII83_19170	COG3391	amine dehydrogenase activity
GII83_19175	COG3391	amine dehydrogenase activity
GII83_19185	COG0457	Tetratricopeptide repeat
GII83_19215	COG1131	(ABC) transporter
GII83_19225	COG0010	Belongs to the arginase family
GII83_19230	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII83_19235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII83_19245	COG1994	Peptidase M50
GII83_19250	COG1942	4-Oxalocrotonate Tautomerase
GII83_19255	COG1846	Transcriptional regulator
GII83_19260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII83_19265	COG0477	Major facilitator Superfamily
GII83_19270	COG1959	2 iron, 2 sulfur cluster binding
GII83_19275	COG3465	dGTPase activity
GII83_19280	COG1078	dGTPase activity
GII83_19285	COG4844	belongs to the
GII83_19295	COG0697	spore germination
GII83_19300	COG0095	Lipoate-protein ligase
GII83_19305	COG0583	DNA-binding transcription factor activity
GII83_19310	COG0280	phosphate acetyltransferase
GII83_19320	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_19325	COG0436	Aminotransferase
GII83_19330	COG2814	Major facilitator Superfamily
GII83_19335	COG0151	Belongs to the GarS family
GII83_19340	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_19345	COG1917	Cupin 2, conserved barrel domain protein
GII83_19350	COG0077	Prephenate dehydratase
GII83_19355	COG2814	Major facilitator Superfamily
GII83_19360	COG0833	amino acid
GII83_19365	COG4187	Peptidase family M20/M25/M40
GII83_19370	COG1012	belongs to the aldehyde dehydrogenase family
GII83_19375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII83_19385	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII83_19390	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII83_19395	COG1088	dTDP-glucose 4,6-dehydratase activity
GII83_19400	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII83_19405	COG3980	spore coat polysaccharide biosynthesis protein
GII83_19410	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII83_19415	COG2089	acid synthase
GII83_19420	COG0456	acetyltransferase
GII83_19425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII83_19430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII83_19435	COG0463	Glycosyl transferase, family 2
GII83_19445	COG2363	Small membrane protein
GII83_19450	COG2233	PERMEase
GII83_19460	COG1012	belongs to the aldehyde dehydrogenase family
GII83_19465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII83_19470	COG1216	Glycosyl transferase, family 2
GII83_19475	COG0351	phosphomethylpyrimidine kinase
GII83_19485	COG1621	beta-fructofuranosidase activity
GII83_19490	COG1263	PTS System
GII83_19490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_19495	COG2116	formate transmembrane transporter activity
GII83_19500	COG3711	transcriptional antiterminator
GII83_19510	COG1404	Belongs to the peptidase S8 family
GII83_19515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII83_19520	COG0778	Nitroreductase
GII83_19525	COG0772	Belongs to the SEDS family
GII83_19535	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII83_19540	COG1845	cytochrome c oxidase, subunit III
GII83_19545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII83_19550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII83_19555	COG2261	transglycosylase associated protein
GII83_19560	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII83_19565	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII83_19570	COG2246	polysaccharide biosynthetic process
GII83_19575	COG1309	transcriptional regulator
GII83_19585	COG3162	membrane
GII83_19590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII83_19595	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII83_19600	COG2837	iron assimilation
GII83_19605	COG2822	iron ion transport
GII83_19610	COG0672	)-iron permease
GII83_19615	COG0352	thiamine-phosphate diphosphorylase activity
GII83_19620	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII83_19625	COG0583	DNA-binding transcription factor activity
GII83_19630	COG1380	Effector of murein hydrolase LrgA
GII83_19635	COG1346	cytolysis
GII83_19640	COG2814	Major facilitator Superfamily
GII83_19645	COG4895	conserved protein (DUF2196)
GII83_19650	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII83_19655	COG0346	lactoylglutathione lyase activity
GII83_19660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII83_19665	COG1404	Belongs to the peptidase S8 family
GII83_19670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_19670	COG1263	PTS System
GII83_19675	COG3711	transcriptional antiterminator
GII83_19680	COG1442	glycosyl transferase family 8
GII83_19685	COG5522	Integral membrane protein (intg_mem_TP0381)
GII83_19690	COG1846	Transcriptional regulator
GII83_19695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII83_19700	COG2234	aminopeptidase activity
GII83_19720	COG2357	RelA SpoT domain protein
GII83_19725	COG1575	Belongs to the MenA family. Type 1 subfamily
GII83_19740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII83_19745	COG1696	Membrane protein involved in D-alanine export
GII83_19750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII83_19755	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII83_19760	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII83_19765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII83_19770	COG1486	melibiose metabolic process
GII83_19775	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII83_19780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII83_19785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII83_19790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII83_19790	COG3711	transcriptional antiterminator
GII83_19800	COG2094	Belongs to the DNA glycosylase MPG family
GII83_19805	COG0753	catalase activity
GII83_19815	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII83_19820	COG1131	(ABC) transporter
GII83_19840	COG1595	DNA-templated transcription, initiation
GII83_19845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII83_19850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII83_19855	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII83_19860	COG4988	ABC transporter
GII83_19865	COG1294	oxidase, subunit
GII83_19870	COG1271	oxidase subunit
GII83_19875	COG3493	citrate carrier protein
GII83_19880	COG0501	Belongs to the peptidase M48B family
GII83_19890	COG0726	polysaccharide deacetylase
GII83_19895	COG3842	ATPase activity
GII83_19900	COG2508	Transcriptional regulator
GII83_19905	COG1012	belongs to the aldehyde dehydrogenase family
GII83_19910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII83_19920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII83_19925	COG1881	PFAM PEBP family protein
GII83_19930	COG0583	DNA-binding transcription factor activity
GII83_19940	COG4585	Histidine kinase
GII83_19945	COG2197	response regulator
GII83_19950	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII83_19960	COG4894	glucomannan catabolic process
GII83_19965	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII83_19970	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII83_19975	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_19980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII83_19985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII83_19990	COG2610	gluconate transmembrane transporter activity
GII83_19995	COG0500	methyltransferase
GII83_20000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII83_20015	COG0753	catalase activity
GII83_20015	COG0693	protein deglycase activity
GII83_20020	COG2851	Citrate transporter
GII83_20025	COG2273	Hydrolase Family 16
GII83_20030	COG3711	transcriptional antiterminator
GII83_20040	COG2270	Major facilitator Superfamily
GII83_20045	COG0513	Belongs to the DEAD box helicase family
GII83_20050	COG3401	FG-GAP repeat protein
GII83_20050	COG2755	lipolytic protein G-D-S-L family
GII83_20080	COG0697	spore germination
GII83_20085	COG0589	response to stress
GII83_20090	COG2723	6-phospho-beta-galactosidase activity
GII83_20095	COG1263	PTS System
GII83_20095	COG2190	(PTS) system
GII83_20095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_20110	COG5444	nuclease activity
GII83_20125	COG3507	Belongs to the glycosyl hydrolase 43 family
GII83_20140	COG2986	histidine ammonia-lyase
GII83_20145	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII83_20150	COG1228	amidohydrolase
GII83_20155	COG0010	Belongs to the arginase family
GII83_20160	COG0833	amino acid
GII83_20165	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII83_20170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII83_20175	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII83_20180	COG2390	Transcriptional regulator
GII83_20190	COG3192	ethanolamine utilization protein
GII83_20195	COG2079	MmgE PrpD family protein
GII83_20205	COG1126	abc transporter atp-binding protein
GII83_20210	COG0765	amino acid transport
GII83_20215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII83_20235	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII83_20240	COG0561	phosphatase activity
GII83_20270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII83_20275	COG5294	Protein conserved in bacteria
GII83_20280	COG0577	efflux transmembrane transporter activity
GII83_20285	COG1136	(ABC) transporter
GII83_20290	COG2205	protein histidine kinase activity
GII83_20295	COG0745	RESPONSE REGULATOR receiver
GII83_20300	COG0191	fructose-bisphosphate aldolase activity
GII83_20305	COG1082	Xylose isomerase domain protein TIM barrel
GII83_20310	COG1082	Xylose isomerase domain protein TIM barrel
GII83_20315	COG0673	inositol 2-dehydrogenase activity
GII83_20320	COG2814	Major facilitator Superfamily
GII83_20325	COG1082	Xylose isomerase domain protein TIM barrel
GII83_20330	COG3962	Belongs to the TPP enzyme family
GII83_20335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII83_20340	COG3718	enzyme involved in inositol metabolism
GII83_20345	COG1012	belongs to the aldehyde dehydrogenase family
GII83_20350	COG1349	DNA-binding transcription factor activity
GII83_20355	COG0667	Aldo Keto reductase
GII83_20370	COG2814	Major facilitator Superfamily
GII83_20375	COG0326	Molecular chaperone. Has ATPase activity
GII83_20385	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_20390	COG1309	transcriptional regulator
GII83_20395	COG1012	belongs to the aldehyde dehydrogenase family
GII83_20400	COG1714	RDD family
GII83_20405	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GII83_20415	COG1714	RDD family
GII83_20420	COG2311	Membrane
GII83_20425	COG1917	Cupin 2, conserved barrel domain protein
GII83_20430	COG1309	transcriptional regulator
GII83_20435	COG1028	Short-chain dehydrogenase reductase Sdr
GII83_20440	COG1846	Transcriptional regulator
GII83_20445	COG1380	Effector of murein hydrolase LrgA
GII83_20450	COG1346	cytolysis
GII83_20455	COG5039	Polysaccharide pyruvyl transferase
GII83_20460	COG1929	Belongs to the glycerate kinase type-1 family
GII83_20465	COG1802	Transcriptional regulator
GII83_20470	COG1070	Carbohydrate kinase
GII83_20475	COG2610	gluconate transmembrane transporter activity
GII83_20480	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII83_20485	COG0450	alkyl hydroperoxide reductase
GII83_20490	COG3634	alkyl hydroperoxide reductase activity
GII83_20500	COG2723	6-phospho-beta-galactosidase activity
GII83_20505	COG2190	(PTS) system
GII83_20510	COG1263	PTS System
GII83_20510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII83_20510	COG2190	(PTS) system
GII83_20515	COG2188	Transcriptional regulator
GII83_20525	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII83_20560	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII83_20575	COG1063	alcohol dehydrogenase
GII83_20595	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII83_20600	COG0456	acetyltransferase
GII83_20605	COG0457	Tetratricopeptide repeat
GII83_20615	COG0010	Belongs to the arginase family
GII83_20620	COG0833	amino acid
GII83_20625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII83_20630	COG3829	transcription factor binding
GII83_20635	COG5002	protein histidine kinase activity
GII83_20660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII83_20665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII83_20670	COG4853	Protein conserved in bacteria
GII83_20675	COG4863	YycH protein
GII83_20680	COG5002	protein histidine kinase activity
GII83_20685	COG0745	RESPONSE REGULATOR receiver
GII83_20715	COG0346	lactoylglutathione lyase activity
GII83_20720	COG0305	Participates in initiation and elongation during chromosome replication
GII83_20735	COG3093	addiction module antidote protein HigA
GII83_20740	COG2807	transmembrane transport
GII83_20745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII83_20750	COG0359	binds to the 23S rRNA
GII83_20755	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII83_20760	COG4241	membrane
GII83_20770	COG5577	PFAM Coat F domain
GII83_20775	COG1733	regulation of RNA biosynthetic process
GII83_20780	COG1227	inorganic diphosphatase activity
GII83_20790	COG2271	Major facilitator Superfamily
GII83_20795	COG0789	Transcriptional regulator
GII83_20795	COG4978	Transcriptional regulator
GII83_20805	COG4319	ketosteroid isomerase
GII83_20810	COG1357	PFAM Pentapeptide repeats (8 copies)
GII83_20815	COG2814	Major facilitator Superfamily
GII83_20820	COG0583	DNA-binding transcription factor activity
GII83_20825	COG2153	protein acetylation
GII83_20835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII83_20840	COG1846	Transcriptional regulator
GII83_20845	COG2153	protein acetylation
GII83_20850	COG2364	Membrane
GII83_20855	COG0456	acetyltransferase
GII83_20860	COG2315	Protein conserved in bacteria
GII83_20865	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII83_20875	COG2814	Major facilitator Superfamily
GII83_20885	COG1331	Highly conserved protein containing a thioredoxin domain
GII83_20900	COG0789	Transcriptional regulator
GII83_20905	COG0697	spore germination
GII83_20915	COG1280	lysine exporter protein (LysE YggA)
GII83_20920	COG1331	Highly conserved protein containing a thioredoxin domain
GII83_20925	COG1331	Highly conserved protein containing a thioredoxin domain
GII83_20930	COG1266	CAAX protease self-immunity
GII83_20935	COG0477	Major facilitator Superfamily
GII83_20935	COG2814	Major facilitator Superfamily
GII83_20940	COG0110	maltose O-acetyltransferase activity
GII83_20945	COG0346	lactoylglutathione lyase activity
GII83_20950	COG1609	Transcriptional regulator
GII83_20955	COG0708	Exodeoxyribonuclease III
GII83_20960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII83_20965	COG0629	single-stranded DNA binding
GII83_20970	COG0360	Binds together with S18 to 16S ribosomal RNA
GII83_20975	COG0012	GTP binding
GII83_20980	COG0243	molybdopterin cofactor binding
GII83_20985	COG4481	Protein conserved in bacteria
GII83_20990	COG3949	Membrane
GII83_21000	COG1475	DNA binding
GII83_21005	COG1192	Involved in chromosome partitioning
GII83_21015	COG1475	DNA binding
GII83_21020	COG0357	Ribosomal RNA small subunit methyltransferase G
GII83_21025	COG0445	tRNA wobble uridine modification
GII83_21030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII83_21035	COG1847	R3H domain protein
GII83_21040	COG0706	membrane insertase activity
GII83_21045	COG0594	ribonuclease P activity
GII83_21050	COG0230	Belongs to the bacterial ribosomal protein bL34 family