locus-tag	class	description
D0808_00010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D0808_00020	COG0405	Gamma-glutamyltransferase
D0808_00025	COG1522	sequence-specific DNA binding
D0808_00030	COG2059	Chromate
D0808_00035	COG2059	Chromate
D0808_00045	COG0655	NAD(P)H dehydrogenase (quinone) activity
D0808_00050	COG0583	DNA-binding transcription factor activity
D0808_00055	COG1515	deoxyribonuclease V activity
D0808_00080	COG5444	nuclease activity
D0808_00095	COG3878	Protein conserved in bacteria
D0808_00100	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D0808_00105	COG4464	protein tyrosine phosphatase activity
D0808_00110	COG0489	protein tyrosine kinase activity
D0808_00115	COG3944	biosynthesis protein
D0808_00125	COG4715	Zinc finger, swim domain protein
D0808_00130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0808_00135	COG0561	phosphatase activity
D0808_00140	COG1349	DNA-binding transcription factor activity
D0808_00145	COG0629	single-stranded DNA binding
D0808_00160	COG3764	Sortase (surface protein transpeptidase)
D0808_00170	COG3279	Response regulator of the LytR AlgR family
D0808_00175	COG2972	Histidine kinase
D0808_00175	COG0745	RESPONSE REGULATOR receiver
D0808_00180	COG1970	mechanosensitive ion channel activity
D0808_00185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0808_00190	COG0457	Tetratricopeptide repeat
D0808_00195	COG4786	Flagellar basal body rod
D0808_00200	COG4786	Flagellar basal body rod
D0808_00205	COG1077	Cell shape determining protein MreB Mrl
D0808_00210	COG1609	Transcriptional regulator
D0808_00220	COG1846	Transcriptional regulator
D0808_00225	COG2814	Major facilitator Superfamily
D0808_00235	COG3420	alginic acid biosynthetic process
D0808_00240	COG1953	Uracil, thiamine, allantoin
D0808_00245	COG0477	Major facilitator Superfamily
D0808_00250	COG1335	isochorismatase
D0808_00260	COG0004	ammonium transporteR
D0808_00265	COG0347	Belongs to the P(II) protein family
D0808_00270	COG0671	phosphoesterase, PA-phosphatase related
D0808_00280	COG0739	heme binding
D0808_00285	COG1247	-acetyltransferase
D0808_00300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0808_00305	COG0789	Transcriptional regulator
D0808_00315	COG2910	NAD(P)H-binding
D0808_00320	COG1959	2 iron, 2 sulfur cluster binding
D0808_00325	COG0804	urea catabolic process
D0808_00330	COG0832	Belongs to the urease beta subunit family
D0808_00335	COG0831	urea catabolic process
D0808_00350	COG3237	CsbD-like
D0808_00355	COG1994	Peptidase M50
D0808_00360	COG0457	Tetratricopeptide repeat
D0808_00370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D0808_00375	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D0808_00385	COG2304	oxidoreductase activity
D0808_00395	COG2304	oxidoreductase activity
D0808_00400	COG2385	sporulation resulting in formation of a cellular spore
D0808_00405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D0808_00415	COG4836	Membrane
D0808_00425	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D0808_00430	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D0808_00435	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D0808_00440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D0808_00445	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D0808_00450	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D0808_00455	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D0808_00460	COG0356	it plays a direct role in the translocation of protons across the membrane
D0808_00470	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D0808_00475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D0808_00480	COG4475	Protein of unknown function (DUF436)
D0808_00485	COG0698	ribose 5-phosphate isomerase
D0808_00490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0808_00495	COG1971	Probably functions as a manganese efflux pump
D0808_00500	COG0009	L-threonylcarbamoyladenylate synthase
D0808_00505	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D0808_00525	COG2890	protein-(glutamine-N5) methyltransferase activity
D0808_00530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D0808_00535	COG0346	lactoylglutathione lyase activity
D0808_00540	COG0789	Transcriptional regulator
D0808_00545	COG0679	Auxin Efflux Carrier
D0808_00550	COG0281	malic enzyme
D0808_00555	COG1435	thymidine kinase activity
D0808_00560	COG0254	rRNA binding
D0808_00565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D0808_00570	COG1494	fructose-1,6-bisphosphatase
D0808_00575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D0808_00580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D0808_00585	COG0191	fructose-bisphosphate aldolase activity
D0808_00590	COG2204	response regulator
D0808_00595	COG4821	SIS domain
D0808_00600	COG0504	CTP synthase activity
D0808_00605	COG3343	RNA polymerase activity
D0808_00610	COG1960	acyl-CoA dehydrogenase activity
D0808_00615	COG0247	lactate metabolic process
D0808_00615	COG2181	nitrate reductase activity
D0808_00620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0808_00625	COG4294	response to UV
D0808_00635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0808_00640	COG1132	(ABC) transporter
D0808_00645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0808_00655	COG2181	nitrate reductase activity
D0808_00660	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D0808_00665	COG1140	nitrate reductase beta subunit
D0808_00670	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D0808_00680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0808_00690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0808_00695	COG2223	nitrite transmembrane transporter activity
D0808_00700	COG0018	arginyl-trna synthetase
D0808_00705	COG4506	Protein conserved in bacteria
D0808_00720	COG0535	radical SAM domain protein
D0808_00730	COG1131	(ABC) transporter
D0808_00735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0808_00740	COG0612	Peptidase, M16
D0808_00745	COG0612	Peptidase, M16
D0808_00755	COG3391	amine dehydrogenase activity
D0808_00760	COG3391	amine dehydrogenase activity
D0808_00770	COG0457	Tetratricopeptide repeat
D0808_00785	COG0010	Belongs to the arginase family
D0808_00790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D0808_00795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0808_00810	COG1994	Peptidase M50
D0808_00815	COG1942	4-Oxalocrotonate Tautomerase
D0808_00820	COG1846	Transcriptional regulator
D0808_00825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D0808_00830	COG0477	Major facilitator Superfamily
D0808_00835	COG1959	2 iron, 2 sulfur cluster binding
D0808_00840	COG3465	dGTPase activity
D0808_00845	COG1078	dGTPase activity
D0808_00850	COG4844	belongs to the
D0808_00860	COG0697	spore germination
D0808_00865	COG0095	Lipoate-protein ligase
D0808_00870	COG0583	DNA-binding transcription factor activity
D0808_00875	COG0280	phosphate acetyltransferase
D0808_00885	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_00890	COG0436	Aminotransferase
D0808_00895	COG2814	Major facilitator Superfamily
D0808_00900	COG0151	Belongs to the GarS family
D0808_00905	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_00910	COG1917	Cupin 2, conserved barrel domain protein
D0808_00915	COG0077	Prephenate dehydratase
D0808_00920	COG2814	Major facilitator Superfamily
D0808_00925	COG0833	amino acid
D0808_00930	COG4187	Peptidase family M20/M25/M40
D0808_00935	COG1012	belongs to the aldehyde dehydrogenase family
D0808_00940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D0808_00950	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D0808_00955	COG1091	dTDP-4-dehydrorhamnose reductase activity
D0808_00960	COG1088	dTDP-glucose 4,6-dehydratase activity
D0808_00965	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D0808_00970	COG3980	spore coat polysaccharide biosynthesis protein
D0808_00975	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D0808_00980	COG2089	acid synthase
D0808_00985	COG0456	acetyltransferase
D0808_00990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0808_00995	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D0808_01000	COG0463	Glycosyl transferase, family 2
D0808_01015	COG2363	Small membrane protein
D0808_01020	COG2233	PERMEase
D0808_01030	COG1012	belongs to the aldehyde dehydrogenase family
D0808_01035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D0808_01040	COG1216	Glycosyl transferase, family 2
D0808_01055	COG1695	Transcriptional regulator
D0808_01060	COG0351	phosphomethylpyrimidine kinase
D0808_01070	COG1621	beta-fructofuranosidase activity
D0808_01075	COG1263	PTS System
D0808_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_01080	COG2116	formate transmembrane transporter activity
D0808_01085	COG3711	transcriptional antiterminator
D0808_01095	COG1404	Belongs to the peptidase S8 family
D0808_01100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_01105	COG0778	Nitroreductase
D0808_01110	COG0772	Belongs to the SEDS family
D0808_01120	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D0808_01125	COG1845	cytochrome c oxidase, subunit III
D0808_01130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D0808_01135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0808_01140	COG2261	transglycosylase associated protein
D0808_01145	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D0808_01150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D0808_01155	COG2246	polysaccharide biosynthetic process
D0808_01160	COG1309	transcriptional regulator
D0808_01170	COG3162	membrane
D0808_01175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0808_01180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D0808_01185	COG2837	iron assimilation
D0808_01190	COG2822	iron ion transport
D0808_01195	COG0672	)-iron permease
D0808_01205	COG0352	thiamine-phosphate diphosphorylase activity
D0808_01210	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D0808_01215	COG0583	DNA-binding transcription factor activity
D0808_01220	COG1380	Effector of murein hydrolase LrgA
D0808_01225	COG1346	cytolysis
D0808_01230	COG2814	Major facilitator Superfamily
D0808_01235	COG4895	conserved protein (DUF2196)
D0808_01240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D0808_01245	COG0346	lactoylglutathione lyase activity
D0808_01255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0808_01265	COG1404	Belongs to the peptidase S8 family
D0808_01270	COG1263	PTS System
D0808_01270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_01275	COG3711	transcriptional antiterminator
D0808_01280	COG1442	glycosyl transferase family 8
D0808_01285	COG5522	Integral membrane protein (intg_mem_TP0381)
D0808_01290	COG1846	Transcriptional regulator
D0808_01295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0808_01300	COG2234	aminopeptidase activity
D0808_01320	COG2357	RelA SpoT domain protein
D0808_01325	COG1575	Belongs to the MenA family. Type 1 subfamily
D0808_01340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_01345	COG1696	Membrane protein involved in D-alanine export
D0808_01350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_01355	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D0808_01360	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D0808_01365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0808_01370	COG1486	melibiose metabolic process
D0808_01375	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0808_01380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0808_01385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0808_01390	COG3711	transcriptional antiterminator
D0808_01390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_01400	COG2094	Belongs to the DNA glycosylase MPG family
D0808_01405	COG0753	catalase activity
D0808_01415	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D0808_01420	COG1131	(ABC) transporter
D0808_01440	COG1595	DNA-templated transcription, initiation
D0808_01445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D0808_01450	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D0808_01455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D0808_01460	COG4988	ABC transporter
D0808_01465	COG1294	oxidase, subunit
D0808_01470	COG1271	oxidase subunit
D0808_01475	COG3493	citrate carrier protein
D0808_01480	COG0501	Belongs to the peptidase M48B family
D0808_01495	COG3842	ATPase activity
D0808_01500	COG2508	Transcriptional regulator
D0808_01505	COG1012	belongs to the aldehyde dehydrogenase family
D0808_01510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_01525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D0808_01535	COG4585	Histidine kinase
D0808_01540	COG2197	response regulator
D0808_01545	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0808_01555	COG4894	glucomannan catabolic process
D0808_01560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0808_01565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0808_01570	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_01575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D0808_01580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D0808_01585	COG2610	gluconate transmembrane transporter activity
D0808_01590	COG0500	methyltransferase
D0808_01595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0808_01610	COG0693	protein deglycase activity
D0808_01610	COG0753	catalase activity
D0808_01615	COG2851	Citrate transporter
D0808_01620	COG2273	Hydrolase Family 16
D0808_01625	COG3711	transcriptional antiterminator
D0808_01635	COG2270	Major facilitator Superfamily
D0808_01640	COG0513	Belongs to the DEAD box helicase family
D0808_01645	COG2755	lipolytic protein G-D-S-L family
D0808_01645	COG3401	FG-GAP repeat protein
D0808_01680	COG0697	spore germination
D0808_01690	COG0789	Transcriptional regulator
D0808_01710	COG0589	response to stress
D0808_01715	COG2723	6-phospho-beta-galactosidase activity
D0808_01720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_01720	COG1263	PTS System
D0808_01720	COG2190	(PTS) system
D0808_01760	COG0494	nUDIX hydrolase
D0808_01770	COG3507	Belongs to the glycosyl hydrolase 43 family
D0808_01785	COG2986	histidine ammonia-lyase
D0808_01790	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D0808_01795	COG1228	amidohydrolase
D0808_01800	COG0010	Belongs to the arginase family
D0808_01805	COG0833	amino acid
D0808_01810	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D0808_01815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0808_01820	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D0808_01825	COG2390	Transcriptional regulator
D0808_01835	COG3192	ethanolamine utilization protein
D0808_01840	COG2079	MmgE PrpD family protein
D0808_01850	COG1126	abc transporter atp-binding protein
D0808_01855	COG0765	amino acid transport
D0808_01860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_01880	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D0808_01885	COG0561	phosphatase activity
D0808_01915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_01920	COG5294	Protein conserved in bacteria
D0808_01925	COG0577	efflux transmembrane transporter activity
D0808_01930	COG1136	(ABC) transporter
D0808_01935	COG2205	protein histidine kinase activity
D0808_01940	COG0745	RESPONSE REGULATOR receiver
D0808_01945	COG0191	fructose-bisphosphate aldolase activity
D0808_01950	COG1082	Xylose isomerase domain protein TIM barrel
D0808_01955	COG1082	Xylose isomerase domain protein TIM barrel
D0808_01960	COG0673	inositol 2-dehydrogenase activity
D0808_01965	COG2814	Major facilitator Superfamily
D0808_01970	COG1082	Xylose isomerase domain protein TIM barrel
D0808_01975	COG3962	Belongs to the TPP enzyme family
D0808_01980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0808_01990	COG1012	belongs to the aldehyde dehydrogenase family
D0808_01995	COG1349	DNA-binding transcription factor activity
D0808_02000	COG0667	Aldo Keto reductase
D0808_02015	COG2814	Major facilitator Superfamily
D0808_02020	COG0326	Molecular chaperone. Has ATPase activity
D0808_02030	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_02035	COG1309	transcriptional regulator
D0808_02040	COG1012	belongs to the aldehyde dehydrogenase family
D0808_02045	COG0456	acetyltransferase
D0808_02050	COG2850	peptidyl-arginine hydroxylation
D0808_02055	COG2226	methyltransferase
D0808_02070	COG0367	asparagine synthase
D0808_02075	COG2814	Major facilitator Superfamily
D0808_02080	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0808_02090	COG1714	RDD family
D0808_02095	COG2311	Membrane
D0808_02100	COG1917	Cupin 2, conserved barrel domain protein
D0808_02105	COG1309	transcriptional regulator
D0808_02110	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_02115	COG1846	Transcriptional regulator
D0808_02120	COG1380	Effector of murein hydrolase LrgA
D0808_02125	COG1346	cytolysis
D0808_02130	COG5039	Polysaccharide pyruvyl transferase
D0808_02135	COG1929	Belongs to the glycerate kinase type-1 family
D0808_02140	COG1802	Transcriptional regulator
D0808_02145	COG1070	Carbohydrate kinase
D0808_02150	COG2610	gluconate transmembrane transporter activity
D0808_02155	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D0808_02160	COG0450	alkyl hydroperoxide reductase
D0808_02165	COG3634	alkyl hydroperoxide reductase activity
D0808_02170	COG2723	6-phospho-beta-galactosidase activity
D0808_02175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_02175	COG2190	(PTS) system
D0808_02175	COG1263	PTS System
D0808_02180	COG2188	Transcriptional regulator
D0808_02185	COG1074	ATP-dependent DNA helicase activity
D0808_02190	COG0501	Belongs to the peptidase M48B family
D0808_02210	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D0808_02225	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D0808_02240	COG1063	alcohol dehydrogenase
D0808_02260	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D0808_02265	COG0456	acetyltransferase
D0808_02270	COG0457	Tetratricopeptide repeat
D0808_02280	COG0010	Belongs to the arginase family
D0808_02285	COG0833	amino acid
D0808_02290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D0808_02295	COG3829	transcription factor binding
D0808_02300	COG5002	protein histidine kinase activity
D0808_02320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0808_02325	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D0808_02330	COG4853	Protein conserved in bacteria
D0808_02335	COG4863	YycH protein
D0808_02340	COG5002	protein histidine kinase activity
D0808_02345	COG0745	RESPONSE REGULATOR receiver
D0808_02375	COG0346	lactoylglutathione lyase activity
D0808_02380	COG0305	Participates in initiation and elongation during chromosome replication
D0808_02395	COG3093	addiction module antidote protein HigA
D0808_02400	COG2807	transmembrane transport
D0808_02405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D0808_02410	COG0359	binds to the 23S rRNA
D0808_02415	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D0808_02420	COG4241	membrane
D0808_02430	COG5577	PFAM Coat F domain
D0808_02435	COG1733	regulation of RNA biosynthetic process
D0808_02440	COG1227	inorganic diphosphatase activity
D0808_02455	COG2271	Major facilitator Superfamily
D0808_02460	COG0789	Transcriptional regulator
D0808_02460	COG4978	Transcriptional regulator
D0808_02470	COG4319	ketosteroid isomerase
D0808_02475	COG1357	PFAM Pentapeptide repeats (8 copies)
D0808_02480	COG2814	Major facilitator Superfamily
D0808_02485	COG0583	DNA-binding transcription factor activity
D0808_02490	COG2153	protein acetylation
D0808_02505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_02510	COG1846	Transcriptional regulator
D0808_02515	COG2153	protein acetylation
D0808_02520	COG2364	Membrane
D0808_02525	COG0456	acetyltransferase
D0808_02530	COG2315	Protein conserved in bacteria
D0808_02535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0808_02545	COG2814	Major facilitator Superfamily
D0808_02555	COG1331	Highly conserved protein containing a thioredoxin domain
D0808_02560	COG1266	CAAX protease self-immunity
D0808_02565	COG0477	Major facilitator Superfamily
D0808_02565	COG2814	Major facilitator Superfamily
D0808_02570	COG0110	maltose O-acetyltransferase activity
D0808_02575	COG0346	lactoylglutathione lyase activity
D0808_02580	COG1609	Transcriptional regulator
D0808_02585	COG0708	Exodeoxyribonuclease III
D0808_02590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D0808_02595	COG0629	single-stranded DNA binding
D0808_02600	COG0360	Binds together with S18 to 16S ribosomal RNA
D0808_02605	COG0012	GTP binding
D0808_02610	COG0243	molybdopterin cofactor binding
D0808_02615	COG4481	Protein conserved in bacteria
D0808_02620	COG3949	Membrane
D0808_02630	COG1475	DNA binding
D0808_02635	COG1192	Involved in chromosome partitioning
D0808_02645	COG1475	DNA binding
D0808_02650	COG0357	Ribosomal RNA small subunit methyltransferase G
D0808_02655	COG0445	tRNA wobble uridine modification
D0808_02660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D0808_02665	COG1847	R3H domain protein
D0808_02670	COG0706	membrane insertase activity
D0808_02675	COG0594	ribonuclease P activity
D0808_02680	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D0808_02685	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D0808_02690	COG0592	DNA-directed DNA polymerase activity
D0808_02695	COG2501	S4 domain
D0808_02700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D0808_02710	COG0187	DNA topoisomerase II activity
D0808_02715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D0808_02740	COG0517	IMP dehydrogenase activity
D0808_02740	COG0516	GMP reductase activity
D0808_02745	COG1686	Belongs to the peptidase S11 family
D0808_02750	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D0808_02755	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D0808_02760	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D0808_02770	COG1428	Deoxynucleoside kinase
D0808_02775	COG1428	Deoxynucleoside kinase
D0808_02780	COG3858	chitin binding
D0808_02780	COG1388	LysM domain
D0808_02785	COG1335	isochorismatase
D0808_02790	COG0590	tRNA wobble adenosine to inosine editing
D0808_02800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D0808_02805	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D0808_02810	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D0808_02845	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D0808_02850	COG3853	Toxic anion resistance protein (TelA)
D0808_02855	COG1982	Orn Lys Arg decarboxylase major
D0808_02860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D0808_02865	COG3870	Protein conserved in bacteria
D0808_02870	COG1728	Protein conserved in bacteria
D0808_02875	COG0470	DNA polymerase III
D0808_02880	COG1774	PSP1 C-terminal conserved region
D0808_02885	COG4467	Involved in initiation control of chromosome replication
D0808_02890	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D0808_02895	COG2827	Endonuclease containing a URI domain
D0808_02900	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D0808_02905	COG2002	toxin-antitoxin pair type II binding
D0808_02910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0808_02910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0808_02915	COG0084	hydrolase, TatD family'
D0808_02920	COG3583	domain protein
D0808_02920	COG3584	3D domain protein
D0808_02925	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D0808_02930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D0808_02940	COG4466	Protein conserved in bacteria
D0808_02950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D0808_02955	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0808_02960	COG0251	oxidation-reduction process
D0808_02965	COG2088	sporulation resulting in formation of a cellular spore
D0808_02970	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D0808_02975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D0808_02980	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D0808_02985	COG0193	aminoacyl-tRNA hydrolase activity
D0808_02995	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D0808_03000	COG2002	toxin-antitoxin pair type II binding
D0808_03005	COG2244	polysaccharide biosynthetic process
D0808_03010	COG3956	TIGRFAM MazG family protein
D0808_03015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D0808_03030	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D0808_03035	COG1098	S1 RNA binding domain
D0808_03050	COG2208	phosphoserine phosphatase activity
D0808_03055	COG2304	oxidoreductase activity
D0808_03060	COG0515	serine threonine protein kinase
D0808_03065	COG0037	tRNA processing
D0808_03075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D0808_03080	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D0808_03085	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D0808_03090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0808_03095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0808_03100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0808_03105	COG0512	Glutamine amidotransferase of anthranilate synthase
D0808_03110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0808_03115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D0808_03120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D0808_03125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0808_03130	COG1396	sequence-specific DNA binding
D0808_03135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0808_03140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D0808_03220	COG4463	regulation of RNA biosynthetic process
D0808_03225	COG3880	PFAM UvrB UvrC protein
D0808_03230	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D0808_03235	COG0542	response to heat
D0808_03240	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D0808_03245	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D0808_03250	COG4956	integral membrane protein (PIN domain superfamily)
D0808_03255	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D0808_03260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D0808_03265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D0808_03275	COG1045	serine acetyltransferase
D0808_03280	COG0215	cysteine-tRNA ligase activity
D0808_03285	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D0808_03290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0808_03295	COG3688	RNA-binding protein containing a PIN domain
D0808_03300	COG1595	DNA-templated transcription, initiation
D0808_03305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D0808_03310	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0808_03315	COG0250	Participates in transcription elongation, termination and antitermination
D0808_03320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D0808_03325	COG0081	regulation of translation
D0808_03330	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D0808_03335	COG0222	ribosome binding
D0808_03340	COG2813	Specifically methylates the guanine in position
D0808_03345	COG0085	RNA polymerase activity
D0808_03350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D0808_03355	COG1358	cellular component organization or biogenesis
D0808_03360	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D0808_03365	COG0049	tRNA binding
D0808_03370	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0808_03375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D0808_03380	COG0596	Alpha beta hydrolase
D0808_03385	COG0051	transcription antitermination factor activity, RNA binding
D0808_03390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D0808_03395	COG0088	Forms part of the polypeptide exit tunnel
D0808_03400	COG0089	rRNA binding
D0808_03405	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D0808_03410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D0808_03415	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D0808_03420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D0808_03425	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D0808_03430	COG0255	Belongs to the universal ribosomal protein uL29 family
D0808_03435	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D0808_03440	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D0808_03450	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D0808_03460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D0808_03465	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D0808_03470	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D0808_03475	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D0808_03480	COG1841	ribosomal large subunit assembly
D0808_03485	COG0200	Binds to the 23S rRNA
D0808_03490	COG0201	protein transport
D0808_03495	COG0563	adenylate kinase activity
D0808_03500	COG0024	Methionine aminopeptidase
D0808_03505	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D0808_03510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D0808_03515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D0808_03520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D0808_03525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D0808_03530	COG0202	RNA polymerase activity
D0808_03535	COG0203	ribosomal protein L17
D0808_03540	COG1122	ATPase activity
D0808_03545	COG1122	ATPase activity
D0808_03550	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D0808_03555	COG0101	tRNA pseudouridine synthase activity
D0808_03560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D0808_03565	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D0808_03570	COG2226	methyltransferase
D0808_03580	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_03585	COG0489	protein tyrosine kinase activity
D0808_03595	COG2194	sulfuric ester hydrolase activity
D0808_03600	COG0726	polysaccharide deacetylase
D0808_03750	COG0659	secondary active sulfate transmembrane transporter activity
D0808_03755	COG0385	Bile acid
D0808_03760	COG2819	hydrolase of the alpha beta superfamily
D0808_03765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_03770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_03775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_03780	COG2207	Transcriptional regulator
D0808_03780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_03785	COG3876	Protein conserved in bacteria
D0808_03790	COG1472	Belongs to the glycosyl hydrolase 3 family
D0808_03795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0808_03800	COG1263	PTS System
D0808_03800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_03805	COG1737	Transcriptional regulator
D0808_03810	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D0808_03815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_03820	COG1683	Conserved Protein
D0808_03850	COG1595	DNA-templated transcription, initiation
D0808_03855	COG5662	AntiSigma factor
D0808_03860	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D0808_03865	COG4856	YbbR-like protein
D0808_03870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0808_03875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D0808_03895	COG0084	hydrolase, TatD family'
D0808_03900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D0808_03905	COG3002	Belongs to the UPF0753 family
D0808_03910	COG0288	reversible hydration of carbon dioxide
D0808_03920	COG5609	conserved protein (DUF2294)
D0808_03925	COG0640	Transcriptional regulator
D0808_03930	COG2814	Major facilitator Superfamily
D0808_03950	COG0596	Alpha beta hydrolase
D0808_03955	COG0745	RESPONSE REGULATOR receiver
D0808_03960	COG0642	Histidine kinase
D0808_03970	COG0515	serine threonine protein kinase
D0808_03985	COG1113	amino acid transport
D0808_04000	COG2602	Beta-lactamase
D0808_04005	COG2124	cytochrome p450
D0808_04015	COG0531	amino acid
D0808_04020	COG0584	glycerophosphoryl diester phosphodiesterase
D0808_04025	COG2271	Major facilitator Superfamily
D0808_04040	COG0456	acetyltransferase
D0808_04040	COG1846	Transcriptional regulator
D0808_04045	COG2271	Major facilitator Superfamily
D0808_04055	COG3409	Peptidoglycan-binding domain 1 protein
D0808_04060	COG0697	spore germination
D0808_04065	COG2207	Transcriptional regulator
D0808_04065	COG1917	Cupin 2, conserved barrel domain protein
D0808_04070	COG1397	ADP-ribosylglycohydrolase
D0808_04075	COG5444	nuclease activity
D0808_04080	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D0808_04085	COG3591	Belongs to the peptidase S1B family
D0808_04095	COG0596	Alpha beta hydrolase
D0808_04100	COG1183	phosphatidylcholine synthase activity
D0808_04105	COG0586	Pfam SNARE associated Golgi protein
D0808_04110	COG0688	phosphatidylethanolamine metabolic process
D0808_04120	COG2312	Erythromycin esterase
D0808_04125	COG2207	Transcriptional regulator
D0808_04135	COG1301	dicarboxylic acid transport
D0808_04140	COG1263	PTS System
D0808_04140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_04140	COG2190	(PTS) system
D0808_04145	COG0363	glucosamine-6-phosphate deaminase activity
D0808_04160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0808_04165	COG0833	amino acid
D0808_04170	COG2040	homocysteine
D0808_04180	COG1115	amino acid carrier protein
D0808_04185	COG2066	Belongs to the glutaminase family
D0808_04190	COG4191	Histidine kinase
D0808_04195	COG0784	Response regulator, receiver
D0808_04205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0808_04210	COG1012	belongs to the aldehyde dehydrogenase family
D0808_04215	COG2271	Major facilitator Superfamily
D0808_04220	COG4948	Mandelate Racemase Muconate Lactonizing
D0808_04225	COG2186	Transcriptional regulator
D0808_04230	COG2721	sulfolactate sulfo-lyase activity
D0808_04235	COG3173	Aminoglycoside phosphotransferase
D0808_04245	COG0697	spore germination
D0808_04250	COG0745	RESPONSE REGULATOR receiver
D0808_04255	COG2205	protein histidine kinase activity
D0808_04260	COG1131	(ABC) transporter
D0808_04275	COG3773	Cell wall hydrolase
D0808_04280	COG2304	oxidoreductase activity
D0808_04290	COG3540	Alkaline phosphatase
D0808_04295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0808_04300	COG0805	protein transport
D0808_04305	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D0808_04310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0808_04315	COG0477	Major facilitator Superfamily
D0808_04320	COG1309	transcriptional regulator
D0808_04330	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D0808_04335	COG1714	RDD family
D0808_04340	COG1405	negative regulation of cell septum assembly
D0808_04340	COG3012	SEC-C Motif Domain Protein
D0808_04345	COG3290	protein histidine kinase activity
D0808_04350	COG3279	Response regulator of the LytR AlgR family
D0808_04355	COG4555	ABC transporter
D0808_04360	COG1668	transmembrane transport
D0808_04365	COG0667	Aldo Keto reductase
D0808_04375	COG1595	DNA-templated transcription, initiation
D0808_04380	COG1595	DNA-templated transcription, initiation
D0808_04385	COG1876	peptidase activity
D0808_04390	COG0457	Tetratricopeptide repeat
D0808_04395	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_04400	COG0366	Alpha amylase catalytic
D0808_04405	COG0803	Belongs to the bacterial solute-binding protein 9 family
D0808_04410	COG1121	(ABC) transporter
D0808_04415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0808_04420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_04425	COG2310	stress, protein
D0808_04430	COG2310	stress, protein
D0808_04435	COG2310	stress, protein
D0808_04440	COG0861	Integral membrane protein TerC family
D0808_04450	COG3853	Toxic anion resistance protein (TelA)
D0808_04455	COG0477	Major facilitator Superfamily
D0808_04465	COG2814	Major facilitator Superfamily
D0808_04470	COG0640	Transcriptional regulator
D0808_04475	COG0517	IMP dehydrogenase activity
D0808_04475	COG4175	Glycine betaine
D0808_04480	COG4176	ABC-type proline glycine betaine transport system permease component
D0808_04485	COG2113	Glycine betaine
D0808_04490	COG1473	amidohydrolase
D0808_04495	COG1288	antiporter activity
D0808_04505	COG0366	Alpha amylase catalytic
D0808_04510	COG0039	L-malate dehydrogenase activity
D0808_04515	COG1620	l-lactate permease
D0808_04520	COG2814	Major facilitator Superfamily
D0808_04525	COG1846	Transcriptional regulator
D0808_04530	COG1280	lysine exporter protein (LysE YggA)
D0808_04535	COG3403	YqcI/YcgG family
D0808_04540	COG1113	amino acid transport
D0808_04545	COG3665	Urea carboxylase-associated protein
D0808_04550	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D0808_04555	COG1660	Displays ATPase and GTPase activities
D0808_04560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D0808_04565	COG2226	methyltransferase
D0808_04570	COG0583	DNA-binding transcription factor activity
D0808_04575	COG3458	cephalosporin-C deacetylase activity
D0808_04580	COG3541	Predicted nucleotidyltransferase
D0808_04585	COG0506	proline dehydrogenase activity
D0808_04590	COG1012	belongs to the aldehyde dehydrogenase family
D0808_04595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0808_04600	COG2508	Transcriptional regulator
D0808_04605	COG3689	TIGRFAM TIGR03943 family protein
D0808_04610	COG0701	Predicted permease
D0808_04615	COG2267	carboxylic ester hydrolase activity
D0808_04620	COG0492	ferredoxin-NADP+ reductase activity
D0808_04625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D0808_04625	COG1587	Uroporphyrinogen-III synthase
D0808_04630	COG2146	nitrite reductase [NAD(P)H] activity
D0808_04635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0808_04640	COG0243	molybdopterin cofactor binding
D0808_04645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0808_04650	COG2223	nitrite transmembrane transporter activity
D0808_04655	COG1469	GTP cyclohydrolase I activity
D0808_04670	COG0523	cobalamin synthesis protein
D0808_04675	COG0765	amino acid transport
D0808_04680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_04690	COG1714	RDD family
D0808_04700	COG1846	Transcriptional regulator
D0808_04725	COG3209	COG3209 Rhs family protein
D0808_04730	COG3290	protein histidine kinase activity
D0808_04730	COG0840	transmembrane signaling receptor activity
D0808_04735	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D0808_04740	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D0808_04745	COG1733	regulation of RNA biosynthetic process
D0808_04750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_04755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_04760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_04765	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D0808_04770	COG2814	Major facilitator Superfamily
D0808_04780	COG0697	spore germination
D0808_04785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_04795	COG2364	Membrane
D0808_04800	COG1126	abc transporter atp-binding protein
D0808_04805	COG0765	amino acid transport
D0808_04810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_04815	COG0583	DNA-binding transcription factor activity
D0808_04820	COG0163	prenyltransferase activity
D0808_04825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D0808_04840	COG0596	Alpha beta hydrolase
D0808_04845	COG3104	oligopeptide transport
D0808_04850	COG5434	Belongs to the glycosyl hydrolase 28 family
D0808_04860	COG0697	spore germination
D0808_04870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D0808_04875	COG1136	(ABC) transporter
D0808_04880	COG0577	efflux transmembrane transporter activity
D0808_04885	COG0745	RESPONSE REGULATOR receiver
D0808_04890	COG5002	protein histidine kinase activity
D0808_04890	COG3850	Histidine kinase
D0808_04895	COG0457	Tetratricopeptide repeat
D0808_04915	COG0527	aspartate kinase activity
D0808_04920	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_04925	COG4605	iron ion homeostasis
D0808_04930	COG4604	ABC transporter, ATP-binding protein
D0808_04935	COG4607	ABC-type enterochelin transport system periplasmic component
D0808_04940	COG2814	Major facilitator Superfamily
D0808_04945	COG1309	transcriptional regulator
D0808_04950	COG0778	Nitroreductase
D0808_04955	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D0808_04960	COG0640	Transcriptional regulator
D0808_04965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_04970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D0808_04975	COG1012	belongs to the aldehyde dehydrogenase family
D0808_04980	COG4975	Glucose uptake
D0808_04985	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_04990	COG4549	nuclear export factor GLE1
D0808_04995	COG1276	copper resistance
D0808_04995	COG2372	response to copper ion
D0808_05000	COG1349	DNA-binding transcription factor activity
D0808_05010	COG2213	PTS system mannitol-specific
D0808_05015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_05020	COG0246	Mannitol dehydrogenase
D0808_05025	COG0473	3-isopropylmalate dehydrogenase activity
D0808_05030	COG0681	Belongs to the peptidase S26 family
D0808_05035	COG0412	Dienelactone hydrolase
D0808_05040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0808_05050	COG0561	phosphatase activity
D0808_05055	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D0808_05060	COG1914	H( )-stimulated, divalent metal cation uptake system
D0808_05065	COG4336	lyase activity
D0808_05070	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D0808_05075	COG1984	allophanate hydrolase subunit 2
D0808_05080	COG1414	Transcriptional regulator
D0808_05085	COG2755	lipolytic protein G-D-S-L family
D0808_05095	COG2329	Antibiotic biosynthesis monooxygenase
D0808_05100	COG0768	penicillin binding
D0808_05105	COG4989	oxidoreductase activity
D0808_05110	COG3711	transcriptional antiterminator
D0808_05115	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_05120	COG2226	methyltransferase
D0808_05125	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_05130	COG1917	Cupin 2, conserved barrel domain protein
D0808_05135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_05140	COG3871	stress protein (general stress protein 26)
D0808_05150	COG2814	Major facilitator Superfamily
D0808_05155	COG1522	sequence-specific DNA binding
D0808_05160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0808_05160	COG0551	DNA topoisomerase type I activity
D0808_05165	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D0808_05170	COG3706	GGDEF domain
D0808_05175	COG5298	Protein conserved in bacteria
D0808_05180	COG1215	transferase activity, transferring glycosyl groups
D0808_05190	COG0531	amino acid
D0808_05195	COG0494	nUDIX hydrolase
D0808_05200	COG0028	Belongs to the TPP enzyme family
D0808_05210	COG1914	H( )-stimulated, divalent metal cation uptake system
D0808_05215	COG2261	transglycosylase associated protein
D0808_05220	COG4876	unkown
D0808_05225	COG2217	Heavy metal translocating P-type atpase
D0808_05230	COG3729	General stress protein
D0808_05235	COG0662	Cupin 2, conserved barrel domain protein
D0808_05240	COG2329	Antibiotic biosynthesis monooxygenase
D0808_05245	COG3546	catalase activity
D0808_05250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D0808_05255	COG3290	protein histidine kinase activity
D0808_05260	COG4565	transcriptional regulatory protein
D0808_05265	COG1301	dicarboxylic acid transport
D0808_05270	COG0628	permease
D0808_05275	COG1131	(ABC) transporter
D0808_05280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D0808_05290	COG1960	acyl-CoA dehydrogenase activity
D0808_05305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0808_05310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_05315	COG1181	Belongs to the D-alanine--D-alanine ligase family
D0808_05320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0808_05330	COG0513	Belongs to the DEAD box helicase family
D0808_05335	COG3402	PFAM membrane-flanked domain
D0808_05340	COG3428	Bacterial PH domain
D0808_05345	COG0705	Rhomboid family
D0808_05350	COG0736	holo-[acyl-carrier-protein] synthase activity
D0808_05355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D0808_05360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D0808_05365	COG0864	Transcriptional regulator
D0808_05370	COG2337	Toxic component of a toxin-antitoxin (TA) module
D0808_05375	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_05380	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_05385	COG2172	sigma factor antagonist activity
D0808_05390	COG2208	phosphoserine phosphatase activity
D0808_05395	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_05400	COG2172	sigma factor antagonist activity
D0808_05405	COG1191	sigma factor activity
D0808_05410	COG2208	phosphoserine phosphatase activity
D0808_05425	COG1673	EVE domain
D0808_05430	COG1846	Transcriptional regulator
D0808_05435	COG2183	response to ionizing radiation
D0808_05445	COG3091	SprT-like family
D0808_05485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_05505	COG1476	TRANSCRIPTIONal
D0808_05515	COG3239	Fatty acid desaturase
D0808_05525	COG1278	Cold shock
D0808_05530	COG1329	Transcriptional regulator
D0808_05540	COG0697	spore germination
D0808_05545	COG1917	Cupin 2, conserved barrel domain protein
D0808_05545	COG2207	Transcriptional regulator
D0808_05550	COG0697	spore germination
D0808_05555	COG2207	Transcriptional regulator
D0808_05555	COG3708	Transcriptional regulator
D0808_05560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_05565	COG0477	Major facilitator Superfamily
D0808_05575	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D0808_05605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_05610	COG1309	transcriptional regulator
D0808_05615	COG0697	spore germination
D0808_05620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_05625	COG2030	dehydratase
D0808_05630	COG3545	Serine hydrolase
D0808_05635	COG1733	regulation of RNA biosynthetic process
D0808_05640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_05645	COG1733	regulation of RNA biosynthetic process
D0808_05650	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0808_05655	COG2814	Major facilitator Superfamily
D0808_05660	COG1309	transcriptional regulator
D0808_05665	COG0640	Transcriptional regulator
D0808_05680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_05685	COG0697	spore germination
D0808_05690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_05695	COG0076	glutamate decarboxylase activity
D0808_05700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D0808_05705	COG0640	Transcriptional regulator
D0808_05710	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D0808_05725	COG4585	Histidine kinase
D0808_05730	COG2197	response regulator
D0808_05735	COG2409	Drug exporters of the RND superfamily
D0808_05740	COG0596	Alpha beta hydrolase
D0808_05745	COG1811	Na channel or pump
D0808_05750	COG0789	Transcriptional regulator
D0808_05750	COG4978	Transcriptional regulator
D0808_05755	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0808_05760	COG0778	Nitroreductase
D0808_05765	COG0346	lactoylglutathione lyase activity
D0808_05770	COG2259	Doxx family
D0808_05775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_05790	COG2323	membrane
D0808_05795	COG2323	membrane
D0808_05800	COG0071	Belongs to the small heat shock protein (HSP20) family
D0808_05815	COG1309	transcriptional regulator
D0808_05825	COG0456	acetyltransferase
D0808_05835	COG1113	amino acid transport
D0808_05840	COG2318	DinB family
D0808_05845	COG1846	Transcriptional regulator
D0808_05850	COG1033	growth of symbiont in host cell
D0808_05850	COG2409	Drug exporters of the RND superfamily
D0808_05855	COG0778	Nitroreductase
D0808_05860	COG1846	Transcriptional regulator
D0808_05865	COG2814	Major facilitator Superfamily
D0808_05870	COG0730	response to heat
D0808_05875	COG1802	Transcriptional regulator
D0808_05880	COG3858	chitin binding
D0808_05880	COG1388	LysM domain
D0808_05885	COG1819	glycosyl
D0808_05895	COG1785	Belongs to the alkaline phosphatase family
D0808_05900	COG5646	InterPro IPR014922
D0808_05910	COG0454	-acetyltransferase
D0808_05915	COG1078	dGTPase activity
D0808_05920	COG1388	LysM domain
D0808_05925	COG2814	Major facilitator Superfamily
D0808_05930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0808_05935	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0808_05940	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0808_05945	COG2723	6-phospho-beta-galactosidase activity
D0808_05950	COG2188	Transcriptional regulator
D0808_05955	COG1940	carbohydrate kinase activity
D0808_05960	COG1482	cell wall glycoprotein biosynthetic process
D0808_05965	COG4124	Belongs to the glycosyl hydrolase 26 family
D0808_06010	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D0808_06015	COG0802	atpase or kinase
D0808_06020	COG1214	PFAM Peptidase M22, glycoprotease
D0808_06025	COG0456	acetyltransferase
D0808_06030	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D0808_06035	COG0488	(ABC) transporter
D0808_06040	COG0315	cyclic pyranopterin monophosphate synthase activity
D0808_06045	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D0808_06050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0808_06055	COG0805	protein transport
D0808_06070	COG1266	CAAX protease self-immunity
D0808_06075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D0808_06080	COG0459	protein refolding
D0808_06105	COG1073	alpha beta
D0808_06110	COG0457	Tetratricopeptide repeat
D0808_06115	COG1063	alcohol dehydrogenase
D0808_06120	COG2211	Major facilitator Superfamily
D0808_06125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0808_06130	COG1842	Phage shock protein A
D0808_06135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D0808_06140	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D0808_06145	COG4260	virion core protein, lumpy skin disease virus
D0808_06155	COG2814	Major facilitator Superfamily
D0808_06160	COG1063	alcohol dehydrogenase
D0808_06165	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D0808_06170	COG0823	Involved in the tonB-independent uptake of proteins
D0808_06185	COG2267	carboxylic ester hydrolase activity
D0808_06195	COG2132	Multicopper oxidase
D0808_06200	COG1113	amino acid transport
D0808_06210	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0808_06215	COG0714	Associated with various cellular activities
D0808_06220	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D0808_06225	COG1305	Transglutaminase-like
D0808_06230	COG0519	Catalyzes the synthesis of GMP from XMP
D0808_06230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D0808_06245	COG2252	PERMEase
D0808_06250	COG3064	Membrane
D0808_06260	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D0808_06270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D0808_06275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D0808_06280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D0808_06285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D0808_06290	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D0808_06295	COG0047	phosphoribosylformylglycinamidine synthase activity
D0808_06300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D0808_06305	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D0808_06310	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D0808_06315	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D0808_06320	COG0138	bifunctional purine biosynthesis protein purh
D0808_06325	COG0151	Belongs to the GarS family
D0808_06330	COG1522	sequence-specific DNA binding
D0808_06335	COG0531	amino acid
D0808_06345	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D0808_06350	COG1470	cell adhesion involved in biofilm formation
D0808_06355	COG4496	protein, YerC YecD
D0808_06360	COG0069	glutamate synthase activity
D0808_06365	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D0808_06370	COG0210	DNA helicase
D0808_06375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D0808_06380	COG4851	CamS sex pheromone cAM373 precursor
D0808_06385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0808_06390	COG1285	pathogenesis
D0808_06395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0808_06400	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D0808_06405	COG0154	amidase activity
D0808_06410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D0808_06415	COG1309	transcriptional regulator
D0808_06420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0808_06425	COG1597	lipid kinase activity
D0808_06430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0808_06455	COG1131	(ABC) transporter
D0808_06475	COG3586	endonuclease activity
D0808_06485	COG0457	Tetratricopeptide repeat
D0808_06495	COG0217	transcriptional regulatory protein
D0808_06505	COG1309	transcriptional regulator
D0808_06510	COG3631	Ketosteroid isomerase-related protein
D0808_06515	COG0702	epimerase
D0808_06530	COG3546	catalase activity
D0808_06535	COG0454	-acetyltransferase
D0808_06545	COG5578	integral membrane protein
D0808_06550	COG2972	Histidine kinase
D0808_06555	COG4753	response regulator
D0808_06555	COG2207	Transcriptional regulator
D0808_06560	COG1653	transport
D0808_06565	COG1175	transmembrane transport
D0808_06570	COG0395	ABC-type sugar transport system, permease component
D0808_06575	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D0808_06580	COG2207	Transcriptional regulator
D0808_06585	COG2755	lipolytic protein G-D-S-L family
D0808_06595	COG5578	integral membrane protein
D0808_06600	COG3401	FG-GAP repeat protein
D0808_06605	COG3401	FG-GAP repeat protein
D0808_06610	COG2755	lipolytic protein G-D-S-L family
D0808_06615	COG1874	Beta-galactosidase
D0808_06625	COG1653	transport
D0808_06630	COG4209	transmembrane transport
D0808_06635	COG0395	ABC-type sugar transport system, permease component
D0808_06640	COG1486	melibiose metabolic process
D0808_06645	COG2323	membrane
D0808_06650	COG2329	Antibiotic biosynthesis monooxygenase
D0808_06655	COG0346	lactoylglutathione lyase activity
D0808_06670	COG5583	Uncharacterized small protein (DUF2292)
D0808_06675	COG0670	Belongs to the BI1 family
D0808_06695	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0808_06695	COG2124	cytochrome p450
D0808_06705	COG1368	sulfuric ester hydrolase activity
D0808_06710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D0808_06715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0808_06720	COG1442	glycosyl transferase family 8
D0808_06725	COG1216	Glycosyl transferase, family 2
D0808_06730	COG1442	glycosyl transferase family 8
D0808_06735	COG2223	nitrite transmembrane transporter activity
D0808_06740	COG1011	Hydrolase
D0808_06745	COG0531	amino acid
D0808_06750	COG1012	belongs to the aldehyde dehydrogenase family
D0808_06755	COG0840	transmembrane signaling receptor activity
D0808_06760	COG0488	(ABC) transporter
D0808_06770	COG0789	Transcriptional regulator
D0808_06775	COG2814	Major facilitator Superfamily
D0808_06790	COG0488	(ABC) transporter
D0808_06795	COG0513	Belongs to the DEAD box helicase family
D0808_06800	COG0456	acetyltransferase
D0808_06805	COG2130	NADP-dependent
D0808_06810	COG1120	ATPase activity
D0808_06815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_06820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_06825	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D0808_06845	COG3866	Pectate lyase
D0808_06850	COG0471	metal ion transport
D0808_06855	COG3290	protein histidine kinase activity
D0808_06860	COG4565	transcriptional regulatory protein
D0808_06865	COG3181	Tripartite tricarboxylate transporter family receptor
D0808_06870	COG2851	Citrate transporter
D0808_06875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_06880	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D0808_06885	COG1254	Belongs to the acylphosphatase family
D0808_06890	COG2258	MOSC domain
D0808_06910	COG0024	Methionine aminopeptidase
D0808_06915	COG1263	PTS System
D0808_06915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_06920	COG1368	sulfuric ester hydrolase activity
D0808_06935	COG1115	amino acid carrier protein
D0808_06950	COG0697	spore germination
D0808_06955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_06955	COG1263	PTS System
D0808_06960	COG0366	Alpha amylase catalytic
D0808_06965	COG2188	Transcriptional regulator
D0808_06970	COG0778	Nitroreductase
D0808_06975	COG0737	Belongs to the 5'-nucleotidase family
D0808_06980	COG0693	protein deglycase activity
D0808_06985	COG2814	Major facilitator Superfamily
D0808_06990	COG4840	Belongs to the UPF0435 family
D0808_06995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0808_07000	COG4980	gas vesicle protein
D0808_07005	COG1295	ribonuclease BN
D0808_07010	COG0477	Major facilitator Superfamily
D0808_07015	COG0387	Pfam Sodium calcium exchanger
D0808_07025	COG0668	transmembrane transport
D0808_07030	COG0535	radical SAM domain protein
D0808_07040	COG0726	polysaccharide deacetylase
D0808_07045	COG2084	Dehydrogenase
D0808_07050	COG0598	Magnesium transport protein CorA
D0808_07055	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D0808_07060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0808_07070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0808_07075	COG4637	Psort location Cytoplasmic, score
D0808_07085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0808_07090	COG0022	dehydrogenase e1 component
D0808_07095	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0808_07100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0808_07105	COG3284	Transcriptional regulator
D0808_07115	COG1742	UPF0060 membrane protein
D0808_07140	COG4842	Belongs to the WXG100 family
D0808_07145	COG1486	melibiose metabolic process
D0808_07150	COG1737	Transcriptional regulator
D0808_07155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_07155	COG1263	PTS System
D0808_07160	COG1132	(ABC) transporter
D0808_07165	COG1132	(ABC) transporter
D0808_07170	COG2259	Doxx family
D0808_07175	COG2514	catechol 2,3-dioxygenase activity
D0808_07180	COG4585	Histidine kinase
D0808_07185	COG2197	response regulator
D0808_07190	COG1131	(ABC) transporter
D0808_07195	COG1511	domain protein
D0808_07195	COG0842	Transport permease protein
D0808_07200	COG0842	Transport permease protein
D0808_07205	COG1695	Transcriptional regulator
D0808_07210	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D0808_07215	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D0808_07220	COG2318	DinB family
D0808_07225	COG2814	Major facilitator Superfamily
D0808_07230	COG1846	Transcriptional regulator
D0808_07235	COG0392	lysyltransferase activity
D0808_07235	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D0808_07240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_07245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_07250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_07255	COG0384	phenazine biosynthesis protein PhzF
D0808_07260	COG0778	Nitroreductase
D0808_07275	COG1090	epimerase
D0808_07280	COG2137	regulation of response to DNA damage stimulus
D0808_07290	COG2814	Major facilitator Superfamily
D0808_07305	COG3103	Sh3 type 3 domain protein
D0808_07310	COG5658	integral membrane protein
D0808_07315	COG0596	Alpha beta hydrolase
D0808_07320	COG0463	Glycosyl transferase, family 2
D0808_07325	COG4485	Bacterial membrane protein, YfhO
D0808_07330	COG1988	membrane-bound metal-dependent
D0808_07335	COG1194	a g-specific adenine glycosylase
D0808_07345	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_07360	COG3557	Belongs to the UPF0374 family
D0808_07365	COG1132	(ABC) transporter
D0808_07370	COG4129	membrane
D0808_07375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D0808_07380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D0808_07385	COG0735	belongs to the Fur family
D0808_07495	COG4326	sporulation control protein
D0808_07505	COG5577	PFAM Coat F domain
D0808_07510	COG3340	Belongs to the peptidase S51 family
D0808_07515	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D0808_07520	COG0277	FAD linked oxidase domain protein
D0808_07530	COG0753	catalase activity
D0808_07535	COG1116	anion transmembrane transporter activity
D0808_07540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D0808_07545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D0808_07550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_07560	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D0808_07570	COG1476	TRANSCRIPTIONal
D0808_07580	COG3382	B3 4 domain protein
D0808_07585	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D0808_07595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D0808_07600	COG0789	Transcriptional regulator
D0808_07605	COG1664	Polymer-forming cytoskeletal
D0808_07610	COG1664	Polymer-forming cytoskeletal
D0808_07615	COG2766	serine protein kinase
D0808_07620	COG2718	Belongs to the UPF0229 family
D0808_07625	COG1846	Transcriptional regulator
D0808_07630	COG1566	PFAM secretion protein HlyD family protein
D0808_07635	COG2814	Major facilitator Superfamily
D0808_07640	COG0655	NAD(P)H dehydrogenase (quinone) activity
D0808_07660	COG1725	Transcriptional regulator
D0808_07665	COG1131	(ABC) transporter
D0808_07670	COG1131	(ABC) transporter
D0808_07675	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D0808_07680	COG1278	Cold shock
D0808_07690	COG1464	Belongs to the NlpA lipoprotein family
D0808_07695	COG3706	GGDEF domain
D0808_07700	COG1823	symporter activity
D0808_07720	COG5577	PFAM Coat F domain
D0808_07725	COG4085	toxin activity
D0808_07725	COG1525	nuclease
D0808_07725	COG0737	Belongs to the 5'-nucleotidase family
D0808_07730	COG3764	Sortase (surface protein transpeptidase)
D0808_07735	COG0564	pseudouridine synthase activity
D0808_07745	COG0517	IMP dehydrogenase activity
D0808_07750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0808_07755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D0808_07755	COG3153	acetyltransferase
D0808_07765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0808_07770	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D0808_07775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D0808_07780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D0808_07785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D0808_07790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0808_07795	COG2203	Gaf domain
D0808_07795	COG4585	Histidine kinase
D0808_07800	COG2197	response regulator
D0808_07805	COG0431	NADPH-dependent FMN reductase
D0808_07820	COG0791	NLP P60 protein
D0808_07820	COG1388	LysM domain
D0808_07825	COG1959	2 iron, 2 sulfur cluster binding
D0808_07830	COG0668	transmembrane transport
D0808_07835	COG2719	SpoVR family
D0808_07840	COG1785	Belongs to the alkaline phosphatase family
D0808_07845	COG1388	LysM domain
D0808_07845	COG0791	NLP P60 protein
D0808_07850	COG0583	DNA-binding transcription factor activity
D0808_07855	COG0372	Belongs to the citrate synthase family
D0808_07860	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_07865	COG0531	amino acid
D0808_07870	COG0733	neurotransmitter:sodium symporter activity
D0808_07875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_07880	COG0456	acetyltransferase
D0808_07895	COG1595	DNA-templated transcription, initiation
D0808_07900	COG0667	Aldo Keto reductase
D0808_07905	COG0204	Acyl-transferase
D0808_07910	COG1253	flavin adenine dinucleotide binding
D0808_07915	COG0789	Transcriptional regulator
D0808_07920	COG0436	Aminotransferase
D0808_07925	COG1253	flavin adenine dinucleotide binding
D0808_07930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D0808_07935	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D0808_07940	COG0584	glycerophosphoryl diester phosphodiesterase
D0808_07950	COG0668	transmembrane transport
D0808_07955	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D0808_07960	COG0726	polysaccharide deacetylase
D0808_07965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0808_07970	COG1757	Na H antiporter
D0808_07975	COG0589	response to stress
D0808_07985	COG1132	(ABC) transporter
D0808_07990	COG1132	(ABC) transporter
D0808_07995	COG0702	epimerase
D0808_08015	COG0189	ligase activity
D0808_08020	COG0189	ligase activity
D0808_08025	COG4399	Belongs to the UPF0754 family
D0808_08030	COG3679	Belongs to the UPF0342 family
D0808_08035	COG4335	DNA alkylation repair
D0808_08040	COG0561	phosphatase activity
D0808_08045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0808_08050	COG0475	glutathione-regulated potassium exporter activity
D0808_08055	COG0490	domain, Protein
D0808_08065	COG1024	Enoyl-CoA hydratase
D0808_08075	COG4152	abc transporter atp-binding protein
D0808_08080	COG1668	transmembrane transport
D0808_08085	COG0420	3'-5' exonuclease activity
D0808_08090	COG4717	serine-type aminopeptidase activity
D0808_08095	COG3481	metal-dependent phosphohydrolase, HD sub domain
D0808_08105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0808_08135	COG1846	Transcriptional regulator
D0808_08140	COG4980	gas vesicle protein
D0808_08155	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D0808_08160	COG0537	adenosine 5'-monophosphoramidase activity
D0808_08165	COG1131	(ABC) transporter
D0808_08170	COG4473	ABC transporter
D0808_08180	COG1473	amidohydrolase
D0808_08185	COG3069	C4-dicarboxylate transmembrane transporter activity
D0808_08195	COG2329	Antibiotic biosynthesis monooxygenase
D0808_08200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0808_08205	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D0808_08220	COG1309	transcriptional regulator
D0808_08225	COG1511	domain protein
D0808_08230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0808_08235	COG4377	Putative membrane peptidase family (DUF2324)
D0808_08245	COG1363	Peptidase, m42
D0808_08250	COG4405	Protein conserved in bacteria
D0808_08255	COG1301	dicarboxylic acid transport
D0808_08265	COG1234	tRNA 3'-trailer cleavage
D0808_08270	COG0095	Lipoate-protein ligase
D0808_08275	COG0702	epimerase
D0808_08280	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_08290	COG0501	Belongs to the peptidase M48B family
D0808_08295	COG1404	Belongs to the peptidase S8 family
D0808_08300	COG0456	acetyltransferase
D0808_08305	COG0604	alcohol dehydrogenase
D0808_08310	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D0808_08315	COG0406	alpha-ribazole phosphatase activity
D0808_08320	COG0183	Belongs to the thiolase family
D0808_08325	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_08330	COG1268	BioY protein
D0808_08335	COG0840	transmembrane signaling receptor activity
D0808_08340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0808_08340	COG0723	plastoquinol--plastocyanin reductase activity
D0808_08345	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_08355	COG4903	ComK protein
D0808_08360	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_08370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0808_08385	COG0398	Pfam SNARE associated Golgi protein
D0808_08390	COG0681	Belongs to the peptidase S26 family
D0808_08395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0808_08400	COG1846	Transcriptional regulator
D0808_08415	COG0738	Major facilitator superfamily
D0808_08420	COG0673	inositol 2-dehydrogenase activity
D0808_08425	COG0561	phosphatase activity
D0808_08430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0808_08435	COG1609	Transcriptional regulator
D0808_08440	COG3180	Ammonia monooxygenase
D0808_08445	COG2814	Major facilitator Superfamily
D0808_08445	COG0477	Major facilitator Superfamily
D0808_08450	COG4533	DNA binding
D0808_08460	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D0808_08465	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D0808_08470	COG1074	ATP-dependent DNA helicase activity
D0808_08475	COG0420	3'-5' exonuclease activity
D0808_08480	COG0419	ATPase involved in DNA repair
D0808_08485	COG1403	HNH endonuclease
D0808_08525	COG5337	Spore coat protein CotH
D0808_08530	COG0179	Fumarylacetoacetate (FAA) hydrolase
D0808_08540	COG1404	Belongs to the peptidase S8 family
D0808_08550	COG0367	asparagine synthase
D0808_08555	COG1562	ergosterol biosynthetic process
D0808_08560	COG0534	Mate efflux family protein
D0808_08565	COG1917	Cupin 2, conserved barrel domain protein
D0808_08565	COG2207	Transcriptional regulator
D0808_08570	COG1609	Transcriptional regulator
D0808_08575	COG0673	inositol 2-dehydrogenase activity
D0808_08580	COG2318	DinB family
D0808_08585	COG1279	arginine transmembrane transporter activity
D0808_08595	COG1357	PFAM Pentapeptide repeats (8 copies)
D0808_08600	COG2267	carboxylic ester hydrolase activity
D0808_08605	COG0529	Catalyzes the synthesis of activated sulfate
D0808_08610	COG2046	Belongs to the sulfate adenylyltransferase family
D0808_08615	COG0175	sulfate reduction
D0808_08620	COG2045	Belongs to the ComB family
D0808_08625	COG1809	phosphosulfolactate synthase activity
D0808_08630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_08635	COG4948	Mandelate Racemase Muconate Lactonizing
D0808_08640	COG2814	Major facilitator Superfamily
D0808_08645	COG0454	-acetyltransferase
D0808_08650	COG2153	protein acetylation
D0808_08655	COG0646	methionine synthase
D0808_08655	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D0808_08660	COG1666	GTP binding
D0808_08665	COG2996	Protein conserved in bacteria
D0808_08685	COG1695	Transcriptional regulator
D0808_08700	COG3227	Zinc metalloprotease (Elastase)
D0808_08705	COG1307	EDD domain protein, DegV family
D0808_08710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_08725	COG0561	phosphatase activity
D0808_08730	COG1073	alpha beta
D0808_08735	COG2151	metal-sulfur cluster biosynthetic enzyme
D0808_08745	COG0277	FAD linked oxidase domain protein
D0808_08750	COG2271	Major facilitator Superfamily
D0808_08755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D0808_08770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D0808_08775	COG0505	Belongs to the CarA family
D0808_08780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D0808_08785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D0808_08800	COG2267	carboxylic ester hydrolase activity
D0808_08810	COG1744	ABC transporter substrate-binding protein PnrA-like
D0808_08825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0808_08830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0808_08835	COG5504	Zn-dependent protease
D0808_08840	COG0444	Belongs to the ABC transporter superfamily
D0808_08845	COG4608	Belongs to the ABC transporter superfamily
D0808_08855	COG0601	transmembrane transport
D0808_08860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0808_08870	COG0180	Tryptophanyl-tRNA synthetase
D0808_08875	COG4166	transmembrane transport
D0808_08880	COG0601	transmembrane transport
D0808_08885	COG0444	Belongs to the ABC transporter superfamily
D0808_08890	COG4608	Belongs to the ABC transporter superfamily
D0808_08895	COG2814	Major facilitator Superfamily
D0808_08900	COG0456	acetyltransferase
D0808_08905	COG1393	Belongs to the ArsC family
D0808_08910	COG0861	Integral membrane protein TerC family
D0808_08915	COG4862	establishment of competence for transformation
D0808_08920	COG4469	Competence protein
D0808_08925	COG1164	Oligoendopeptidase f
D0808_08945	COG2346	COG2346, Truncated hemoglobins
D0808_08950	COG0741	lytic transglycosylase activity
D0808_08955	COG4116	CYTH
D0808_08965	COG2357	RelA SpoT domain protein
D0808_08970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D0808_08975	COG0564	pseudouridine synthase activity
D0808_08980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D0808_08985	COG0569	domain protein
D0808_08985	COG0475	glutathione-regulated potassium exporter activity
D0808_08990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D0808_08995	COG0352	thiamine-phosphate diphosphorylase activity
D0808_09000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0808_09005	COG2104	thiamine diphosphate biosynthetic process
D0808_09010	COG2022	thiamine diphosphate biosynthetic process
D0808_09015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D0808_09020	COG0351	phosphomethylpyrimidine kinase
D0808_09025	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D0808_09080	COG0210	DNA helicase
D0808_09090	COG2153	protein acetylation
D0808_09095	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D0808_09100	COG2382	esterase
D0808_09105	COG0626	cystathionine gamma-synthase activity
D0808_09110	COG0626	cystathionine gamma-synthase activity
D0808_09115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_09120	COG5505	Protein of unknown function (DUF819)
D0808_09150	COG5444	nuclease activity
D0808_09175	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D0808_09180	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_09190	COG3711	transcriptional antiterminator
D0808_09190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_09195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0808_09195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_09195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0808_09200	COG1482	cell wall glycoprotein biosynthetic process
D0808_09210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_09220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D0808_09240	COG0109	protoheme IX farnesyltransferase activity
D0808_09250	COG0726	polysaccharide deacetylase
D0808_09265	COG5504	Zn-dependent protease
D0808_09270	COG2205	protein histidine kinase activity
D0808_09280	COG3383	formate dehydrogenase (NAD+) activity
D0808_09285	COG2427	Protein of unknown function (DUF1641)
D0808_09295	COG1051	belongs to the nudix hydrolase family
D0808_09305	COG2124	cytochrome p450
D0808_09310	COG1819	glycosyl
D0808_09320	COG1587	Uroporphyrinogen-III synthase
D0808_09325	COG0390	transport system, permease component
D0808_09330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0808_09340	COG4297	protein containing double-stranded beta helix domain
D0808_09350	COG1252	NADH dehydrogenase
D0808_09355	COG1904	glucuronate isomerase
D0808_09360	COG2211	Major facilitator Superfamily
D0808_09365	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D0808_09370	COG1063	alcohol dehydrogenase
D0808_09375	COG1312	Catalyzes the dehydration of D-mannonate
D0808_09380	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_09385	COG2271	Major facilitator Superfamily
D0808_09390	COG1609	Transcriptional regulator
D0808_09395	COG0246	Mannitol dehydrogenase
D0808_09400	COG2721	sulfolactate sulfo-lyase activity
D0808_09405	COG0730	response to heat
D0808_09410	COG2318	DinB family
D0808_09415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D0808_09420	COG0457	Tetratricopeptide repeat
D0808_09430	COG2350	Protein conserved in bacteria
D0808_09435	COG1388	LysM domain
D0808_09435	COG5632	N-Acetylmuramoyl-L-alanine amidase
D0808_09435	COG3409	Peptidoglycan-binding domain 1 protein
D0808_09445	COG4195	phage-related replication protein
D0808_09450	COG3546	catalase activity
D0808_09455	COG2856	Zn peptidase
D0808_09460	COG1396	sequence-specific DNA binding
D0808_09470	COG1522	sequence-specific DNA binding
D0808_09475	COG1484	DNA-dependent DNA replication
D0808_09495	COG1595	DNA-templated transcription, initiation
D0808_09500	COG5484	DNA packaging
D0808_09500	COG3728	DNA packaging
D0808_09505	COG1783	phage Terminase large subunit
D0808_09510	COG5518	Phage portal protein
D0808_09515	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D0808_09520	COG4653	Phage capsid family
D0808_09570	COG5412	phage tail tape measure protein
D0808_09570	COG3953	SLT domain
D0808_09575	COG1652	LysM domain
D0808_09580	COG4193	domain, Protein
D0808_09590	COG3628	GPW Gp25 family protein
D0808_09595	COG3299	homolog of phage Mu protein gp47
D0808_09600	COG3778	Protein conserved in bacteria
D0808_09640	COG3409	Peptidoglycan-binding domain 1 protein
D0808_09640	COG5632	N-Acetylmuramoyl-L-alanine amidase
D0808_09655	COG0306	phosphate transporter
D0808_09660	COG1392	Phosphate transport regulator
D0808_09665	COG0531	amino acid
D0808_09670	COG0346	lactoylglutathione lyase activity
D0808_09675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D0808_09680	COG0463	Glycosyl transferase, family 2
D0808_09685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0808_09690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0808_09695	COG2362	D-Aminopeptidase
D0808_09700	COG0601	transmembrane transport
D0808_09705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0808_09710	COG0444	Belongs to the ABC transporter superfamily
D0808_09715	COG4166	transmembrane transport
D0808_09720	COG1619	proteins homologs of microcin C7 resistance protein MccF
D0808_09725	COG4948	Mandelate Racemase Muconate Lactonizing
D0808_09730	COG0791	NLP P60 protein
D0808_09735	COG4608	Belongs to the ABC transporter superfamily
D0808_09740	COG2706	6-phosphogluconolactonase activity
D0808_09745	COG1834	amidinotransferase
D0808_09750	COG1607	acyl-coa hydrolase
D0808_09755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0808_09755	COG1017	nitric oxide dioxygenase activity
D0808_09765	COG2323	membrane
D0808_09770	COG2318	DinB family
D0808_09775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_09780	COG2076	Multidrug Resistance protein
D0808_09785	COG2076	Multidrug Resistance protein
D0808_09790	COG0788	formyltetrahydrofolate deformylase activity
D0808_09795	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D0808_09800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D0808_09805	COG1764	response to oxidative stress
D0808_09810	COG1846	Transcriptional regulator
D0808_09815	COG1764	response to oxidative stress
D0808_09820	COG0590	tRNA wobble adenosine to inosine editing
D0808_09825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0808_09830	COG1404	Belongs to the peptidase S8 family
D0808_09835	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_09840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D0808_09845	COG1122	ATPase activity
D0808_09850	COG4721	ABC-type cobalt transport system, permease component
D0808_09860	COG0745	RESPONSE REGULATOR receiver
D0808_09865	COG5002	protein histidine kinase activity
D0808_09865	COG3850	Histidine kinase
D0808_09870	COG3212	peptidase
D0808_09875	COG3212	peptidase
D0808_09890	COG2239	Acts as a magnesium transporter
D0808_09895	COG0789	Transcriptional regulator
D0808_09910	COG1846	Transcriptional regulator
D0808_09915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0808_09920	COG0726	polysaccharide deacetylase
D0808_09925	COG1408	metallophosphoesterase
D0808_09935	COG0463	Glycosyl transferase, family 2
D0808_09940	COG3285	dna ligase
D0808_09940	COG1793	dna ligase
D0808_09945	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D0808_09950	COG3300	MHYT domain
D0808_09950	COG5001	Diguanylate cyclase
D0808_09955	COG0586	Pfam SNARE associated Golgi protein
D0808_09960	COG0861	Integral membrane protein TerC family
D0808_09965	COG1191	sigma factor activity
D0808_09985	COG0501	Belongs to the peptidase M48B family
D0808_09990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0808_10005	COG3594	Acyltransferase
D0808_10010	COG5002	protein histidine kinase activity
D0808_10015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D0808_10020	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D0808_10025	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D0808_10030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D0808_10035	COG0436	Aminotransferase
D0808_10040	COG1850	ribulose-bisphosphate carboxylase activity
D0808_10045	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D0808_10050	COG0235	Class ii aldolase
D0808_10055	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D0808_10060	COG3339	Conserved Protein
D0808_10075	COG3852	Histidine kinase
D0808_10080	COG1846	Transcriptional regulator
D0808_10085	COG1360	Flagellar Motor Protein
D0808_10090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0808_10095	COG0542	response to heat
D0808_10100	COG3949	Membrane
D0808_10105	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D0808_10110	COG0720	synthase
D0808_10115	COG0602	queuosine metabolic process
D0808_10120	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D0808_10125	COG1733	regulation of RNA biosynthetic process
D0808_10130	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_10135	COG4641	Protein conserved in bacteria
D0808_10135	COG1388	LysM domain
D0808_10140	COG1388	LysM domain
D0808_10145	COG3858	chitin binding
D0808_10155	COG4873	Protein conserved in bacteria
D0808_10165	COG3773	Cell wall hydrolase
D0808_10170	COG2244	polysaccharide biosynthetic process
D0808_10175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_10180	COG2217	Heavy metal translocating P-type atpase
D0808_10190	COG0006	proline dipeptidase activity
D0808_10195	COG1609	Transcriptional regulator
D0808_10200	COG3711	transcriptional antiterminator
D0808_10205	COG2190	(PTS) system
D0808_10205	COG1263	PTS System
D0808_10205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_10210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_10215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D0808_10225	COG1533	DNA photolyase activity
D0808_10230	COG0456	acetyltransferase
D0808_10235	COG0840	transmembrane signaling receptor activity
D0808_10240	COG2084	Dehydrogenase
D0808_10245	COG2340	Cysteine-rich secretory protein family
D0808_10250	COG0768	penicillin binding
D0808_10255	COG4191	Histidine kinase
D0808_10260	COG0436	Aminotransferase
D0808_10270	COG0784	Response regulator, receiver
D0808_10270	COG0835	chemotaxis
D0808_10280	COG2814	Major facilitator Superfamily
D0808_10285	COG1376	ErfK ybiS ycfS ynhG family protein
D0808_10290	COG1408	metallophosphoesterase
D0808_10295	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_10300	COG2200	EAL domain
D0808_10310	COG4703	Protein of unknown function (DUF1797)
D0808_10315	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D0808_10325	COG0517	IMP dehydrogenase activity
D0808_10330	COG0583	DNA-binding transcription factor activity
D0808_10335	COG0716	FMN binding
D0808_10345	COG0716	FMN binding
D0808_10350	COG2171	N-acyltransferase activity
D0808_10355	COG1473	amidohydrolase
D0808_10365	COG0668	transmembrane transport
D0808_10370	COG0450	alkyl hydroperoxide reductase
D0808_10375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_10390	COG0746	molybdenum cofactor guanylyltransferase activity
D0808_10395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D0808_10400	COG0303	'Molybdopterin
D0808_10405	COG1763	Mo-molybdopterin cofactor biosynthetic process
D0808_10410	COG0314	molybdopterin synthase activity
D0808_10415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D0808_10420	COG1132	(ABC) transporter
D0808_10425	COG1132	(ABC) transporter
D0808_10435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0808_10440	COG1136	(ABC) transporter
D0808_10445	COG0577	efflux transmembrane transporter activity
D0808_10450	COG1349	DNA-binding transcription factor activity
D0808_10455	COG1105	Belongs to the carbohydrate kinase PfkB family
D0808_10460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0808_10460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0808_10460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_10465	COG0681	Belongs to the peptidase S26 family
D0808_10475	COG0488	(ABC) transporter
D0808_10480	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D0808_10485	COG2309	aminopeptidase activity
D0808_10495	COG1077	Cell shape determining protein MreB Mrl
D0808_10500	COG2002	toxin-antitoxin pair type II binding
D0808_10505	COG3852	Histidine kinase
D0808_10510	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D0808_10510	COG2105	PFAM AIG2 family protein
D0808_10515	COG0569	domain protein
D0808_10520	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D0808_10525	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D0808_10535	COG0561	phosphatase activity
D0808_10540	COG0242	peptide deformylase activity
D0808_10550	COG0497	DNA recombination
D0808_10555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0808_10560	COG0022	dehydrogenase e1 component
D0808_10565	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0808_10570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0808_10575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_10585	COG1982	Orn Lys Arg decarboxylase major
D0808_10590	COG4476	Belongs to the UPF0223 family
D0808_10595	COG4493	Belongs to the UPF0637 family
D0808_10605	COG0483	inositol monophosphate 1-phosphatase activity
D0808_10615	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D0808_10635	COG1595	DNA-templated transcription, initiation
D0808_10665	COG4896	Protein conserved in bacteria
D0808_10675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D0808_10680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D0808_10685	COG2066	Belongs to the glutaminase family
D0808_10690	COG4838	Belongs to the UPF0358 family
D0808_10695	COG0772	Belongs to the SEDS family
D0808_10700	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D0808_10705	COG1612	heme a metabolic process
D0808_10710	COG0109	protoheme IX farnesyltransferase activity
D0808_10715	COG2010	Cytochrome c
D0808_10715	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0808_10720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D0808_10725	COG1845	cytochrome c oxidase, subunit III
D0808_10730	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D0808_10735	COG3336	cytochrome c oxidase
D0808_10745	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D0808_10750	COG2340	Cysteine-rich secretory protein family
D0808_10765	COG3679	Belongs to the UPF0342 family
D0808_10770	COG4471	UPF0298 protein
D0808_10775	COG0742	ribosomal rna small subunit methyltransferase
D0808_10780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D0808_10785	COG3314	Sporulation integral membrane protein YlbJ
D0808_10790	COG1752	Esterase of the alpha-beta hydrolase superfamily
D0808_10795	COG3480	Lon protease (S16) C-terminal proteolytic domain
D0808_10815	COG1399	metal-binding, possibly nucleic acid-binding protein
D0808_10820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D0808_10830	COG0454	-acetyltransferase
D0808_10835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D0808_10840	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D0808_10845	COG2001	Belongs to the MraZ family
D0808_10850	COG0275	rRNA processing
D0808_10855	COG4839	cell division protein FtsL
D0808_10865	COG0768	penicillin binding
D0808_10870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D0808_10875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D0808_10880	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D0808_10885	COG0772	Belongs to the SEDS family
D0808_10890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0808_10895	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D0808_10900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D0808_10905	COG3879	Bacterial protein of unknown function (DUF881)
D0808_10910	COG3879	Bacterial protein of unknown function (DUF881)
D0808_10915	COG3856	small basic protein
D0808_10920	COG0849	cell division
D0808_10925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D0808_10930	COG4412	M6 family metalloprotease domain protein
D0808_10930	COG1404	Belongs to the peptidase S8 family
D0808_10940	COG1191	sigma factor activity
D0808_10945	COG1191	sigma factor activity
D0808_10950	COG1119	ATPase activity
D0808_10955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0808_10960	COG1873	PFAM PRC-barrel domain
D0808_10970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D0808_10975	COG1799	cell septum assembly
D0808_10980	COG0762	integral membrane protein
D0808_10985	COG2302	S4 RNA-binding domain
D0808_10990	COG3599	regulation of cell shape
D0808_10995	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D0808_11000	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0808_11005	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D0808_11010	COG0564	pseudouridine synthase activity
D0808_11015	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D0808_11020	COG2233	PERMEase
D0808_11025	COG0540	Belongs to the ATCase OTCase family
D0808_11030	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D0808_11035	COG0505	Belongs to the CarA family
D0808_11040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D0808_11045	COG0543	2 iron, 2 sulfur cluster binding
D0808_11050	COG0167	dihydroorotate dehydrogenase activity
D0808_11055	COG0284	orotidine-5'-phosphate decarboxylase activity
D0808_11060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D0808_11065	COG0175	sulfate reduction
D0808_11070	COG0306	phosphate transporter
D0808_11075	COG2046	Belongs to the sulfate adenylyltransferase family
D0808_11080	COG0529	Catalyzes the synthesis of activated sulfate
D0808_11085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D0808_11090	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D0808_11095	COG1648	precorrin-2 dehydrogenase activity
D0808_11105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0808_11110	COG1561	YicC-like family, N-terminal region
D0808_11115	COG2052	Domain of unknown function (DUF370)
D0808_11120	COG0194	GDP metabolic process
D0808_11125	COG1758	RNA polymerase activity
D0808_11130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0808_11135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D0808_11140	COG0242	peptide deformylase activity
D0808_11145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D0808_11150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0808_11150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0808_11155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D0808_11160	COG0631	protein serine/threonine phosphatase activity
D0808_11165	COG0515	serine threonine protein kinase
D0808_11165	COG2815	serine threonine protein kinase
D0808_11170	COG1162	GTPase activity
D0808_11175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D0808_11180	COG1564	THIamine pyrophosphokinase
D0808_11190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D0808_11195	COG1302	Protein conserved in bacteria
D0808_11200	COG1461	Dihydroxyacetone kinase
D0808_11205	COG1760	l-serine dehydratase
D0808_11210	COG1760	l-serine dehydratase
D0808_11215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D0808_11220	COG1349	DNA-binding transcription factor activity
D0808_11220	COG2050	protein possibly involved in aromatic compounds catabolism
D0808_11225	COG0416	fatty acid biosynthetic process
D0808_11230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D0808_11235	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_11240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_11245	COG0571	ribonuclease III activity
D0808_11250	COG1196	nuclear chromosome segregation
D0808_11255	COG0552	protein localization to endoplasmic reticulum
D0808_11265	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D0808_11270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D0808_11275	COG0228	four-way junction DNA binding
D0808_11280	COG1837	Belongs to the UPF0109 family
D0808_11290	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D0808_11295	COG0336	Belongs to the RNA methyltransferase TrmD family
D0808_11300	COG0335	large ribosomal subunit rRNA binding
D0808_11305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0808_11310	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D0808_11320	COG2257	FlhB HrpN YscU SpaS Family
D0808_11325	COG0045	succinate-CoA ligase (ADP-forming) activity
D0808_11330	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D0808_11335	COG0758	DNA mediated transformation
D0808_11340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0808_11345	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D0808_11350	COG4974	Belongs to the 'phage' integrase family
D0808_11355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D0808_11360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D0808_11365	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D0808_11370	COG1815	bacterial-type flagellum-dependent cell motility
D0808_11375	COG1558	bacterial-type flagellum-dependent cell motility
D0808_11380	COG1677	Flagellar hook-basal body complex protein FliE
D0808_11385	COG1766	The M ring may be actively involved in energy transduction
D0808_11390	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0808_11395	COG1317	bacterial-type flagellum organization
D0808_11400	COG1157	protein secretion by the type III secretion system
D0808_11405	COG2882	bacterial-type flagellum organization
D0808_11410	COG3334	PFAM MgtE intracellular
D0808_11415	COG3144	bacterial-type flagellum assembly
D0808_11420	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D0808_11425	COG4786	Flagellar basal body rod
D0808_11430	COG1582	Flagellar protein (FlbD)
D0808_11435	COG1580	Controls the rotational direction of flagella during chemotaxis
D0808_11440	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0808_11445	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0808_11445	COG1776	CheC inhibitor of MCP methylation
D0808_11450	COG2201	protein-glutamate methylesterase activity
D0808_11455	COG3190	flagellar
D0808_11460	COG1338	Plays a role in the flagellum-specific transport system
D0808_11465	COG1987	bacterial-type flagellum assembly
D0808_11470	COG1684	flagellar biosynthetic protein fliR
D0808_11475	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D0808_11480	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D0808_11485	COG1419	protein localization to endoplasmic reticulum
D0808_11490	COG0455	bacterial-type flagellum organization
D0808_11495	COG2201	protein-glutamate methylesterase activity
D0808_11500	COG2198	Histidine kinase
D0808_11500	COG0643	Histidine kinase
D0808_11505	COG0835	chemotaxis
D0808_11510	COG1776	CheC inhibitor of MCP methylation
D0808_11515	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D0808_11520	COG1191	sigma factor activity
D0808_11530	COG0052	Belongs to the universal ribosomal protein uS2 family
D0808_11535	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D0808_11540	COG0528	UMP kinase activity
D0808_11545	COG0233	cytoplasmic translational termination
D0808_11550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D0808_11555	COG4589	Belongs to the CDS family
D0808_11560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D0808_11565	COG0750	zinc metalloprotease
D0808_11570	COG0442	prolyl-tRNA aminoacylation
D0808_11575	COG2176	DNA-directed DNA polymerase activity
D0808_11580	COG0779	Required for maturation of 30S ribosomal subunits
D0808_11585	COG0195	Participates in both transcription termination and antitermination
D0808_11590	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D0808_11595	COG1358	cellular component organization or biogenesis
D0808_11600	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D0808_11605	COG1550	Protein conserved in bacteria
D0808_11610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D0808_11615	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D0808_11620	COG0196	riboflavin kinase activity
D0808_11625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D0808_11630	COG1185	polyribonucleotide nucleotidyltransferase activity
D0808_11635	COG0726	polysaccharide deacetylase
D0808_11640	COG0612	Peptidase, M16
D0808_11645	COG1873	PFAM PRC-barrel domain
D0808_11650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0808_11655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0808_11660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D0808_11665	COG0527	aspartate kinase activity
D0808_11670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0808_11675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D0808_11680	COG0740	serine-type endopeptidase activity
D0808_11690	COG4980	gas vesicle protein
D0808_11690	COG1674	ftsk spoiiie
D0808_11695	COG2188	Transcriptional regulator
D0808_11700	COG2814	Major facilitator Superfamily
D0808_11705	COG0612	Peptidase, M16
D0808_11710	COG0612	Peptidase, M16
D0808_11715	COG0300	oxidoreductase activity
D0808_11730	COG1426	Protein conserved in bacteria
D0808_11735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D0808_11740	COG1546	Belongs to the CinA family
D0808_11740	COG1058	Belongs to the CinA family
D0808_11745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D0808_11750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0808_11755	COG1418	mRNA catabolic process
D0808_11760	COG1692	metallophosphoesterase
D0808_11765	COG2359	stage V sporulation protein S
D0808_11770	COG1063	alcohol dehydrogenase
D0808_11775	COG0156	8-amino-7-oxononanoate synthase activity
D0808_11780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D0808_11785	COG4550	Control of competence regulator ComK, YlbF/YmcA
D0808_11795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D0808_11800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D0808_11815	COG3226	Transcriptional regulator
D0808_11820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_11830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D0808_11835	COG3321	synthase
D0808_11840	COG2070	2-Nitropropane dioxygenase
D0808_11840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D0808_11845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_11850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0808_11855	COG3425	synthase
D0808_11860	COG1024	Enoyl-CoA hydratase
D0808_11865	COG1024	Enoyl-CoA hydratase
D0808_11870	COG3321	synthase
D0808_11870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_11870	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_11870	COG0300	oxidoreductase activity
D0808_11870	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_11875	COG3321	synthase
D0808_11875	COG4221	oxidoreductase activity
D0808_11875	COG0300	oxidoreductase activity
D0808_11875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_11880	COG3321	synthase
D0808_11880	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_11880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_11880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0808_11880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_11885	COG4221	oxidoreductase activity
D0808_11885	COG3321	synthase
D0808_11885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_11885	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_11890	COG3321	synthase
D0808_11890	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D0808_11890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0808_11890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_11895	COG2124	cytochrome p450
D0808_11905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_11910	COG1404	Belongs to the peptidase S8 family
D0808_11920	COG4195	phage-related replication protein
D0808_11925	COG1764	response to oxidative stress
D0808_11930	COG2076	Multidrug Resistance protein
D0808_11935	COG2076	Multidrug Resistance protein
D0808_11950	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D0808_11955	COG1923	regulation of RNA biosynthetic process
D0808_11970	COG1780	Probably involved in ribonucleotide reductase function
D0808_11975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0808_11980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0808_11985	COG4112	unkown
D0808_11990	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_12000	COG0464	growth
D0808_12005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D0808_12010	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D0808_12015	COG0789	Transcriptional regulator
D0808_12020	COG0174	glutamine synthetase
D0808_12040	COG4282	regulation of fungal-type cell wall biogenesis
D0808_12055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_12070	COG3655	Transcriptional regulator
D0808_12095	COG0135	phosphoribosylanthranilate isomerase activity
D0808_12100	COG2211	Major facilitator Superfamily
D0808_12105	COG3507	Belongs to the glycosyl hydrolase 43 family
D0808_12110	COG1940	carbohydrate kinase activity
D0808_12115	COG2115	Belongs to the xylose isomerase family
D0808_12120	COG1070	Carbohydrate kinase
D0808_12130	COG1525	nuclease
D0808_12135	COG2814	Major facilitator Superfamily
D0808_12140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D0808_12150	COG0756	dUTP diphosphatase activity
D0808_12160	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D0808_12185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0808_12195	COG3832	glyoxalase III activity
D0808_12205	COG0697	spore germination
D0808_12210	COG0531	amino acid
D0808_12240	COG4195	phage-related replication protein
D0808_12250	COG0346	lactoylglutathione lyase activity
D0808_12260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D0808_12265	COG1388	LysM domain
D0808_12270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0808_12275	COG4224	UPF0291 protein
D0808_12280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D0808_12290	COG3763	UPF0154 protein
D0808_12300	COG0785	Cytochrome C biogenesis protein
D0808_12305	COG2201	protein-glutamate methylesterase activity
D0808_12310	COG4846	Membrane protein involved in cytochrome C biogenesis
D0808_12320	COG0071	Belongs to the small heat shock protein (HSP20) family
D0808_12335	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D0808_12340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_12360	COG0824	Thioesterase
D0808_12370	COG4841	protein insertion into membrane
D0808_12375	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D0808_12380	COG1832	CoA-binding protein
D0808_12385	COG0187	DNA topoisomerase II activity
D0808_12390	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D0808_12400	COG1115	amino acid carrier protein
D0808_12405	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D0808_12415	COG5520	Belongs to the glycosyl hydrolase 30 family
D0808_12420	COG3507	Belongs to the glycosyl hydrolase 43 family
D0808_12430	COG2246	polysaccharide biosynthetic process
D0808_12435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0808_12440	COG0586	Pfam SNARE associated Golgi protein
D0808_12445	COG2404	hydrolase activity, acting on ester bonds
D0808_12450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D0808_12455	COG1024	Enoyl-CoA hydratase
D0808_12460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D0808_12465	COG0511	ligase activity, forming carbon-carbon bonds
D0808_12470	COG0439	Biotin carboxylase
D0808_12475	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_12480	COG1960	acyl-CoA dehydrogenase activity
D0808_12490	COG1649	PFAM Uncharacterised BCR, COG1649
D0808_12500	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D0808_12500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_12510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_12515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_12520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_12525	COG2027	D-alanyl-D-alanine carboxypeptidase
D0808_12530	COG2017	converts alpha-aldose to the beta-anomer
D0808_12535	COG0534	Mate efflux family protein
D0808_12550	COG0582	viral genome integration into host DNA
D0808_12555	COG0166	Belongs to the GPI family
D0808_12560	COG0405	Gamma-glutamyltransferase
D0808_12565	COG0583	DNA-binding transcription factor activity
D0808_12570	COG0604	alcohol dehydrogenase
D0808_12575	COG0493	'glutamate synthase
D0808_12580	COG0070	glutamate synthase
D0808_12580	COG0067	glutamate synthase
D0808_12580	COG0069	glutamate synthase activity
D0808_12585	COG0583	DNA-binding transcription factor activity
D0808_12590	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D0808_12595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0808_12605	COG0300	oxidoreductase activity
D0808_12610	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D0808_12620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_12635	COG1131	(ABC) transporter
D0808_12645	COG2814	Major facilitator Superfamily
D0808_12650	COG1070	Carbohydrate kinase
D0808_12655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0808_12660	COG0243	molybdopterin cofactor binding
D0808_12690	COG2368	4-hydroxyphenylacetate
D0808_12695	COG4305	rare lipoprotein A
D0808_12700	COG3619	membrane
D0808_12705	COG3866	Pectate lyase
D0808_12710	COG2135	peptidase activity
D0808_12720	COG2140	Oxalate decarboxylase
D0808_12745	COG2720	vancomycin resistance protein
D0808_12760	COG3739	integral membrane protein
D0808_12765	COG0583	DNA-binding transcription factor activity
D0808_12770	COG0697	spore germination
D0808_12780	COG0693	protein deglycase activity
D0808_12785	COG2367	Beta-lactamase
D0808_12805	COG3848	Pyruvate phosphate dikinase
D0808_12805	COG0574	Belongs to the PEP-utilizing enzyme family
D0808_12810	COG0726	polysaccharide deacetylase
D0808_12815	COG2314	TM2 domain
D0808_12865	COG1231	oxidoreductase activity
D0808_12870	COG5434	Belongs to the glycosyl hydrolase 28 family
D0808_12875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0808_12880	COG2207	Transcriptional regulator
D0808_12880	COG0662	Cupin 2, conserved barrel domain protein
D0808_12885	COG0456	acetyltransferase
D0808_12890	COG1309	transcriptional regulator
D0808_12895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_12900	COG3708	Transcriptional regulator
D0808_12905	COG2378	regulation of single-species biofilm formation
D0808_12915	COG0640	Transcriptional regulator
D0808_12920	COG0741	lytic transglycosylase activity
D0808_12925	COG2322	membrane
D0808_12940	COG1619	proteins homologs of microcin C7 resistance protein MccF
D0808_12945	COG3239	Fatty acid desaturase
D0808_12950	COG4585	Histidine kinase
D0808_12955	COG2197	response regulator
D0808_12960	COG3584	3D domain protein
D0808_12960	COG1388	LysM domain
D0808_12965	COG0514	ATP-dependent DNA helicase (RecQ)
D0808_12980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D0808_12985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0808_13000	COG0071	Belongs to the small heat shock protein (HSP20) family
D0808_13025	COG1012	belongs to the aldehyde dehydrogenase family
D0808_13030	COG1657	PFAM Prenyltransferase squalene oxidase
D0808_13035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D0808_13040	COG0733	neurotransmitter:sodium symporter activity
D0808_13045	COG0385	Bile acid
D0808_13050	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0808_13055	COG0567	Dehydrogenase, E1 component
D0808_13060	COG4548	von Willebrand factor, type A
D0808_13065	COG0714	Associated with various cellular activities
D0808_13070	COG2032	superoxide dismutase activity
D0808_13075	COG1388	LysM domain
D0808_13075	COG0791	NLP P60 protein
D0808_13080	COG1819	glycosyl
D0808_13085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D0808_13090	COG0534	Mate efflux family protein
D0808_13095	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_13100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D0808_13105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D0808_13115	COG2962	Rard protein
D0808_13130	COG2610	gluconate transmembrane transporter activity
D0808_13135	COG1942	4-Oxalocrotonate Tautomerase
D0808_13140	COG1733	regulation of RNA biosynthetic process
D0808_13145	COG0778	Nitroreductase
D0808_13150	COG0400	carboxylic ester hydrolase activity
D0808_13155	COG0346	lactoylglutathione lyase activity
D0808_13165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0808_13170	COG3409	Peptidoglycan-binding domain 1 protein
D0808_13170	COG0793	Belongs to the peptidase S41A family
D0808_13175	COG2226	methyltransferase
D0808_13185	COG1876	peptidase activity
D0808_13190	COG0813	purine-nucleoside phosphorylase activity
D0808_13205	COG0671	phosphoesterase, PA-phosphatase related
D0808_13230	COG4479	Belongs to the UPF0346 family
D0808_13240	COG1509	lysine 2,3-aminomutase activity
D0808_13245	COG0456	acetyltransferase
D0808_13250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0808_13255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D0808_13260	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D0808_13265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0808_13275	COG0456	acetyltransferase
D0808_13280	COG0463	Glycosyl transferase, family 2
D0808_13295	COG4641	Protein conserved in bacteria
D0808_13300	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D0808_13305	COG1086	Polysaccharide biosynthesis protein
D0808_13310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0808_13315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0808_13320	COG1846	Transcriptional regulator
D0808_13325	COG0534	Mate efflux family protein
D0808_13335	COG4698	Protein conserved in bacteria
D0808_13340	COG2755	lipolytic protein G-D-S-L family
D0808_13345	COG1999	signal sequence binding
D0808_13355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D0808_13360	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D0808_13365	COG1272	protein, Hemolysin III
D0808_13370	COG0204	Acyl-transferase
D0808_13375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0808_13380	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D0808_13385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0808_13395	COG2136	Putative SAM-dependent methyltransferase
D0808_13395	COG2521	methyltransferase
D0808_13405	COG0129	dihydroxy-acid dehydratase activity
D0808_13410	COG1413	lyase activity
D0808_13415	COG1418	mRNA catabolic process
D0808_13420	COG0386	Belongs to the glutathione peroxidase family
D0808_13425	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D0808_13430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0808_13435	COG1278	Cold shock
D0808_13455	COG0328	RNA-DNA hybrid ribonuclease activity
D0808_13460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D0808_13465	COG0328	RNA-DNA hybrid ribonuclease activity
D0808_13475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0808_13490	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D0808_13500	COG1755	Isoprenylcysteine carboxyl methyltransferase
D0808_13505	COG3424	synthase
D0808_13510	COG2233	PERMEase
D0808_13515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0808_13520	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D0808_13530	COG0800	Aldolase
D0808_13535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0808_13540	COG1609	Transcriptional regulator
D0808_13545	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D0808_13550	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_13555	COG1199	ATP-dependent helicase activity
D0808_13570	COG0116	Belongs to the methyltransferase superfamily
D0808_13585	COG4474	Belongs to the UPF0398 family
D0808_13595	COG3359	exonuclease
D0808_13600	COG1111	helicase
D0808_13600	COG1205	dead DEAH box helicase
D0808_13605	COG2190	(PTS) system
D0808_13610	COG0071	Belongs to the small heat shock protein (HSP20) family
D0808_13645	COG3331	DNA recombination
D0808_13650	COG4499	WXG100 protein secretion system (Wss), protein YukC
D0808_13650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0808_13660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D0808_13665	COG3935	DnaD domain protein
D0808_13670	COG0017	Asparaginyl-tRNA synthetase
D0808_13675	COG0436	Aminotransferase
D0808_13680	COG5353	protein conserved in bacteria
D0808_13690	COG1199	ATP-dependent helicase activity
D0808_13690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D0808_13695	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D0808_13700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D0808_13705	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D0808_13710	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D0808_13710	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D0808_13715	COG0617	tRNA 3'-terminal CCA addition
D0808_13720	COG0438	transferase activity, transferring glycosyl groups
D0808_13725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D0808_13730	COG1803	Methylglyoxal synthase
D0808_13735	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D0808_13740	COG1694	Mazg nucleotide pyrophosphohydrolase
D0808_13745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_13755	COG4347	Protein of unknown function (DUF1405)
D0808_13760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D0808_13760	COG2010	Cytochrome c
D0808_13765	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D0808_13770	COG0723	plastoquinol--plastocyanin reductase activity
D0808_13780	COG5582	Belongs to the UPF0302 family
D0808_13785	COG0457	Tetratricopeptide repeat
D0808_13790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D0808_13795	COG0287	Prephenate dehydrogenase
D0808_13800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D0808_13805	COG0159	tryptophan synthase activity
D0808_13810	COG0133	tryptophan synthase activity
D0808_13815	COG0135	phosphoribosylanthranilate isomerase activity
D0808_13825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D0808_13830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0808_13835	COG4401	Chorismate mutase type I
D0808_13840	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D0808_13845	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D0808_13850	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D0808_13855	COG0105	UTP biosynthetic process
D0808_13860	COG0142	geranyltranstransferase activity
D0808_13865	COG2226	methyltransferase
D0808_13870	COG0142	geranyltranstransferase activity
D0808_13880	COG0302	gtp cyclohydrolase
D0808_13885	COG0776	regulation of translation
D0808_13890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D0808_13905	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D0808_13910	COG1160	GTP binding
D0808_13935	COG1304	FMN binding
D0808_13940	COG0539	negative regulation of cytoplasmic translation
D0808_13945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D0808_13955	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D0808_13960	COG2959	enzyme of heme biosynthesis
D0808_13965	COG3409	Peptidoglycan-binding domain 1 protein
D0808_13965	COG3773	Cell wall hydrolase
D0808_13970	COG2339	peptidase activity
D0808_13975	COG0492	ferredoxin-NADP+ reductase activity
D0808_13980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D0808_13985	COG4862	establishment of competence for transformation
D0808_13990	COG1408	metallophosphoesterase
D0808_14000	COG1388	LysM domain
D0808_14005	COG1266	CAAX protease self-immunity
D0808_14010	COG0514	ATP-dependent DNA helicase (RecQ)
D0808_14015	COG4955	Helix-turn-helix domain
D0808_14020	COG1141	Ferredoxin
D0808_14025	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D0808_14030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0808_14035	COG0710	3-dehydroquinate dehydratase activity
D0808_14045	COG1595	DNA-templated transcription, initiation
D0808_14050	COG5002	protein histidine kinase activity
D0808_14055	COG0745	RESPONSE REGULATOR receiver
D0808_14060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0808_14065	COG1333	cytochrome c biogenesis protein
D0808_14070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_14075	COG1187	pseudouridine synthase activity
D0808_14080	COG0700	Nucleoside recognition
D0808_14085	COG2715	membrane protein required for spore maturation
D0808_14090	COG1686	Belongs to the peptidase S11 family
D0808_14100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D0808_14105	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D0808_14110	COG1547	Domain of unknown function (DUF309)
D0808_14115	COG0456	acetyltransferase
D0808_14120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D0808_14125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0808_14125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0808_14130	COG0307	riboflavin synthase, alpha
D0808_14135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0808_14135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0808_14145	COG0681	Belongs to the peptidase S26 family
D0808_14155	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D0808_14210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D0808_14220	COG4086	secreted protein
D0808_14225	COG0019	diaminopimelate decarboxylase activity
D0808_14230	COG0697	spore germination
D0808_14245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0808_14265	COG1191	sigma factor activity
D0808_14270	COG2172	sigma factor antagonist activity
D0808_14275	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_14280	COG1686	Belongs to the peptidase S11 family
D0808_14285	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D0808_14290	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D0808_14295	COG4974	Belongs to the 'phage' integrase family
D0808_14305	COG0735	belongs to the Fur family
D0808_14310	COG1300	Membrane
D0808_14320	COG0281	malic enzyme
D0808_14325	COG1757	Na H antiporter
D0808_14330	COG1027	Aspartate ammonia-lyase
D0808_14335	COG0252	asparaginase activity
D0808_14340	COG1396	sequence-specific DNA binding
D0808_14345	COG1379	DNA repair
D0808_14350	COG0494	nUDIX hydrolase
D0808_14360	COG0667	Aldo Keto reductase
D0808_14370	COG1073	alpha beta
D0808_14380	COG4918	Iron-sulphur cluster biosynthesis
D0808_14385	COG0456	acetyltransferase
D0808_14385	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D0808_14390	COG2329	Antibiotic biosynthesis monooxygenase
D0808_14395	COG0456	acetyltransferase
D0808_14405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0808_14415	COG2211	Major facilitator Superfamily
D0808_14425	COG0346	lactoylglutathione lyase activity
D0808_14430	COG1072	(Pantothenic acid kinase))
D0808_14435	COG3048	D-serine ammonia-lyase activity
D0808_14440	COG0300	oxidoreductase activity
D0808_14445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_14450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0808_14455	COG4187	Peptidase family M20/M25/M40
D0808_14460	COG1902	pentaerythritol trinitrate reductase activity
D0808_14465	COG0596	Alpha beta hydrolase
D0808_14475	COG1234	tRNA 3'-trailer cleavage
D0808_14480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D0808_14485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D0808_14490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0808_14500	COG0706	membrane insertase activity
D0808_14505	COG3361	conserved protein (COG2071)
D0808_14510	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0808_14515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D0808_14520	COG0346	lactoylglutathione lyase activity
D0808_14525	COG1376	ErfK ybiS ycfS ynhG family protein
D0808_14530	COG4129	membrane
D0808_14535	COG1126	abc transporter atp-binding protein
D0808_14540	COG0765	amino acid transport
D0808_14545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_14555	COG1597	lipid kinase activity
D0808_14560	COG2814	Major facilitator Superfamily
D0808_14565	COG0789	Transcriptional regulator
D0808_14565	COG4978	Transcriptional regulator
D0808_14570	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0808_14575	COG0022	dehydrogenase e1 component
D0808_14580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0808_14585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0808_14590	COG3426	butyrate kinase activity
D0808_14595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D0808_14600	COG0280	phosphate acetyltransferase
D0808_14605	COG3829	transcription factor binding
D0808_14605	COG3290	protein histidine kinase activity
D0808_14615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D0808_14620	COG2079	MmgE PrpD family protein
D0808_14625	COG0372	Belongs to the citrate synthase family
D0808_14630	COG1960	acyl-CoA dehydrogenase activity
D0808_14635	COG1250	3-hydroxyacyl-CoA dehydrogenase
D0808_14640	COG0183	Belongs to the thiolase family
D0808_14645	COG0584	glycerophosphoryl diester phosphodiesterase
D0808_14650	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_14660	COG1902	pentaerythritol trinitrate reductase activity
D0808_14665	COG0745	RESPONSE REGULATOR receiver
D0808_14670	COG0750	zinc metalloprotease
D0808_14675	COG0497	DNA recombination
D0808_14680	COG1438	arginine binding
D0808_14685	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D0808_14690	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D0808_14695	COG0142	geranyltranstransferase activity
D0808_14700	COG1722	exodeoxyribonuclease VII activity
D0808_14705	COG1570	exodeoxyribonuclease VII activity
D0808_14710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D0808_14715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0808_14720	COG1302	Protein conserved in bacteria
D0808_14725	COG0439	Biotin carboxylase
D0808_14730	COG0511	ligase activity, forming carbon-carbon bonds
D0808_14770	COG3854	ATPases associated with a variety of cellular activities
D0808_14780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D0808_14785	COG0006	proline dipeptidase activity
D0808_14790	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D0808_14800	COG3872	metal-dependent enzyme
D0808_14810	COG1752	Esterase of the alpha-beta hydrolase superfamily
D0808_14815	COG1321	iron dependent repressor
D0808_14820	COG0095	Lipoate-protein ligase
D0808_14825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0808_14830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0808_14835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0808_14840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D0808_14845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0808_14860	COG1396	sequence-specific DNA binding
D0808_14870	COG0681	Belongs to the peptidase S26 family
D0808_14895	COG4940	Competence protein ComGF
D0808_14905	COG4970	Tfp pilus assembly protein FimT
D0808_14910	COG4537	Required for transformation and DNA binding
D0808_14915	COG1459	type II secretion system
D0808_14920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0808_14930	COG0598	Magnesium transport protein CorA
D0808_14935	COG1253	flavin adenine dinucleotide binding
D0808_14940	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_14950	COG1393	Belongs to the ArsC family
D0808_14960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_14970	COG0011	TIGRFAM Protein of
D0808_14980	COG2866	Carboxypeptidase
D0808_14985	COG1368	sulfuric ester hydrolase activity
D0808_14990	COG1940	carbohydrate kinase activity
D0808_14995	COG4483	Protein conserved in bacteria
D0808_15000	COG0457	Tetratricopeptide repeat
D0808_15000	COG0705	Rhomboid family
D0808_15010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D0808_15015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D0808_15020	COG0438	transferase activity, transferring glycosyl groups
D0808_15035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0808_15040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0808_15045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0808_15050	COG0581	inorganic phosphate transmembrane transporter activity
D0808_15055	COG0573	inorganic phosphate transmembrane transporter activity
D0808_15060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D0808_15070	COG0477	Major facilitator Superfamily
D0808_15075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D0808_15080	COG2839	Protein conserved in bacteria
D0808_15085	COG5521	maltodextrose utilization protein MalA
D0808_15090	COG1388	LysM domain
D0808_15095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D0808_15100	COG4709	membrane
D0808_15105	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D0808_15110	COG0735	belongs to the Fur family
D0808_15115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_15125	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D0808_15130	COG0513	Belongs to the DEAD box helicase family
D0808_15140	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D0808_15145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D0808_15150	COG2384	SAM-dependent methyltransferase
D0808_15155	COG2010	Cytochrome c
D0808_15165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D0808_15170	COG0358	DNA primase activity
D0808_15175	COG1671	Belongs to the UPF0178 family
D0808_15180	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D0808_15185	COG0517	IMP dehydrogenase activity
D0808_15190	COG0751	glycine-tRNA ligase activity
D0808_15195	COG0752	glycyl-tRNA synthetase alpha subunit
D0808_15200	COG1381	Involved in DNA repair and RecF pathway recombination
D0808_15210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D0808_15215	COG0295	cytidine deaminase activity
D0808_15220	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D0808_15225	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D0808_15230	COG1480	7TM receptor with intracellular HD hydrolase
D0808_15235	COG1702	phosphate starvation-inducible protein PhoH
D0808_15240	COG0561	phosphatase activity
D0808_15255	COG4864	UPF0365 protein
D0808_15260	COG1030	water channel activity
D0808_15265	COG1610	YqeY-like protein
D0808_15270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D0808_15275	COG1283	sodium-dependent phosphate transmembrane transporter activity
D0808_15280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D0808_15285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D0808_15290	COG2264	protein methyltransferase activity
D0808_15295	COG0484	heat shock protein binding
D0808_15300	COG0443	Heat shock 70 kDa protein
D0808_15305	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D0808_15310	COG1420	regulation of RNA biosynthetic process
D0808_15315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0808_15320	COG0481	GTPase activity
D0808_15330	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_15335	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D0808_15340	COG0268	Binds directly to 16S ribosomal RNA
D0808_15345	COG1466	dna polymerase III delta subunit
D0808_15355	COG2333	competence protein COMEC
D0808_15355	COG0658	competence protein
D0808_15360	COG2131	deaminase
D0808_15365	COG1555	photosystem II stabilization
D0808_15365	COG1596	polysaccharide export
D0808_15370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0808_15375	COG2226	methyltransferase
D0808_15380	COG0799	negative regulation of ribosome biogenesis
D0808_15385	COG1713	HD superfamily hydrolase involved in NAD metabolism
D0808_15390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D0808_15395	COG1534	Rna-binding protein
D0808_15400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D0808_15405	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0808_15410	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D0808_15420	COG2755	lipolytic protein G-D-S-L family
D0808_15425	COG5632	N-Acetylmuramoyl-L-alanine amidase
D0808_15425	COG3409	Peptidoglycan-binding domain 1 protein
D0808_15430	COG0398	Pfam SNARE associated Golgi protein
D0808_15435	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D0808_15445	COG3209	COG3209 Rhs family protein
D0808_15455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0808_15465	COG1063	alcohol dehydrogenase
D0808_15475	COG4221	oxidoreductase activity
D0808_15495	COG0702	epimerase
D0808_15505	COG0457	Tetratricopeptide repeat
D0808_15515	COG5444	nuclease activity
D0808_15580	COG3778	Protein conserved in bacteria
D0808_15585	COG3299	homolog of phage Mu protein gp47
D0808_15590	COG3628	GPW Gp25 family protein
D0808_15600	COG4193	domain, Protein
D0808_15605	COG1652	LysM domain
D0808_15610	COG3953	SLT domain
D0808_15610	COG5280	Phage tail tape measure protein TP901
D0808_15670	COG4653	Phage capsid family
D0808_15675	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D0808_15685	COG2369	cell adhesion
D0808_15690	COG5518	Phage portal protein
D0808_15695	COG1783	phage Terminase large subunit
D0808_15700	COG5484	DNA packaging
D0808_15720	COG3677	Transposase
D0808_15735	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D0808_15745	COG1484	DNA-dependent DNA replication
D0808_15750	COG3935	DnaD domain protein
D0808_15755	COG3723	Recombinational DNA repair protein, rece pathway
D0808_15760	COG5377	YqaJ viral recombinase family
D0808_15790	COG3620	sequence-specific DNA binding
D0808_15800	COG2856	Zn peptidase
D0808_15810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0808_15820	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0808_15830	COG0697	spore germination
D0808_15835	COG1802	Transcriptional regulator
D0808_15840	COG0730	response to heat
D0808_15845	COG0425	Belongs to the sulfur carrier protein TusA family
D0808_15850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_15850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0808_15860	COG0425	Belongs to the sulfur carrier protein TusA family
D0808_15860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0808_15870	COG2210	Belongs to the sulfur carrier protein TusA family
D0808_15875	COG1937	Protein conserved in bacteria
D0808_15890	COG0662	Cupin 2, conserved barrel domain protein
D0808_15905	COG0789	Transcriptional regulator
D0808_15905	COG4978	Transcriptional regulator
D0808_15910	COG2814	Major facilitator Superfamily
D0808_15915	COG0456	acetyltransferase
D0808_15920	COG1253	flavin adenine dinucleotide binding
D0808_15930	COG0697	spore germination
D0808_15935	COG0583	DNA-binding transcription factor activity
D0808_15940	COG2072	flavoprotein involved in K transport
D0808_15945	COG1230	cation diffusion facilitator family transporter
D0808_15950	COG1942	4-Oxalocrotonate Tautomerase
D0808_15955	COG0583	DNA-binding transcription factor activity
D0808_15965	COG1114	Component of the transport system for branched-chain amino acids
D0808_15970	COG1687	branched-chain amino acid
D0808_15975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D0808_15980	COG1522	sequence-specific DNA binding
D0808_15985	COG2732	(Barnase) inhibitor
D0808_15990	COG2124	cytochrome p450
D0808_16005	COG1609	Transcriptional regulator
D0808_16015	COG1175	transmembrane transport
D0808_16020	COG0395	ABC-type sugar transport system, permease component
D0808_16040	COG0110	maltose O-acetyltransferase activity
D0808_16050	COG1335	isochorismatase
D0808_16065	COG2318	DinB family
D0808_16075	COG2070	2-Nitropropane dioxygenase
D0808_16090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D0808_16100	COG2186	Transcriptional regulator
D0808_16115	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_16120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D0808_16125	COG3959	Transketolase, thiamine diphosphate binding domain
D0808_16140	COG4978	Transcriptional regulator
D0808_16140	COG0789	Transcriptional regulator
D0808_16145	COG2315	Protein conserved in bacteria
D0808_16155	COG3443	Belongs to the bacterial solute-binding protein 9 family
D0808_16160	COG1595	DNA-templated transcription, initiation
D0808_16165	COG0667	Aldo Keto reductase
D0808_16170	COG3409	Peptidoglycan-binding domain 1 protein
D0808_16175	COG5566	PFAM Mor transcription activator
D0808_16180	COG0596	Alpha beta hydrolase
D0808_16185	COG4991	sh3 domain protein
D0808_16190	COG4991	sh3 domain protein
D0808_16195	COG0346	lactoylglutathione lyase activity
D0808_16205	COG5577	PFAM Coat F domain
D0808_16210	COG1063	alcohol dehydrogenase
D0808_16220	COG5577	PFAM Coat F domain
D0808_16225	COG0789	Transcriptional regulator
D0808_16235	COG1064	alcohol dehydrogenase
D0808_16240	COG0693	protein deglycase activity
D0808_16245	COG1621	beta-fructofuranosidase activity
D0808_16250	COG3716	PTS system mannose fructose sorbose family IID component
D0808_16255	COG3715	PTS system
D0808_16260	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_16265	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_16270	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D0808_16270	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D0808_16275	COG1113	amino acid transport
D0808_16280	COG1280	lysine exporter protein (LysE YggA)
D0808_16285	COG1378	Sugar-specific transcriptional regulator TrmB
D0808_16290	COG1595	DNA-templated transcription, initiation
D0808_16300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D0808_16300	COG2755	lipolytic protein G-D-S-L family
D0808_16310	COG2124	cytochrome p450
D0808_16310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0808_16315	COG1309	transcriptional regulator
D0808_16320	COG2226	methyltransferase
D0808_16330	COG2116	formate transmembrane transporter activity
D0808_16335	COG5609	conserved protein (DUF2294)
D0808_16340	COG3383	formate dehydrogenase (NAD+) activity
D0808_16345	COG2427	Protein of unknown function (DUF1641)
D0808_16355	COG0626	cystathionine gamma-synthase activity
D0808_16360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0808_16365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D0808_16370	COG2226	methyltransferase
D0808_16385	COG0768	penicillin binding
D0808_16390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0808_16395	COG0572	uridine kinase
D0808_16415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0808_16420	COG3906	Belongs to the UPF0473 family
D0808_16425	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D0808_16430	COG4472	Bacterial protein of unknown function (DUF965)
D0808_16435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D0808_16440	COG0628	permease
D0808_16445	COG1126	abc transporter atp-binding protein
D0808_16450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_16455	COG0765	amino acid transport
D0808_16460	COG0765	amino acid transport
D0808_16475	COG3881	PFAM PRC-barrel domain
D0808_16480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D0808_16485	COG0457	Tetratricopeptide repeat
D0808_16490	COG0482	sulfurtransferase activity
D0808_16495	COG1104	cysteine desulfurase activity
D0808_16500	COG1959	2 iron, 2 sulfur cluster binding
D0808_16505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D0808_16510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D0808_16520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D0808_16525	COG0124	histidyl-tRNA synthetase
D0808_16535	COG4991	sh3 domain protein
D0808_16535	COG3103	Sh3 type 3 domain protein
D0808_16535	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_16540	COG1490	D-aminoacyl-tRNA deacylase activity
D0808_16545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D0808_16550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0808_16555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D0808_16555	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D0808_16560	COG5416	Lipopolysaccharide assembly protein A domain
D0808_16565	COG0490	domain, Protein
D0808_16570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0808_16570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0808_16580	COG2244	polysaccharide biosynthetic process
D0808_16585	COG2323	membrane
D0808_16595	COG1862	Preprotein translocase
D0808_16600	COG0343	queuine tRNA-ribosyltransferase activity
D0808_16605	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D0808_16615	COG2255	four-way junction helicase activity
D0808_16620	COG0632	four-way junction helicase activity
D0808_16630	COG2814	Major facilitator Superfamily
D0808_16635	COG0673	inositol 2-dehydrogenase activity
D0808_16640	COG2112	serine threonine protein kinase
D0808_16655	COG1115	amino acid carrier protein
D0808_16660	COG0217	transcriptional regulatory protein
D0808_16670	COG1388	LysM domain
D0808_16675	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D0808_16680	COG0157	Belongs to the NadC ModD family
D0808_16685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D0808_16690	COG1104	cysteine desulfurase activity
D0808_16695	COG1827	regulation of RNA biosynthetic process
D0808_16700	COG0077	Prephenate dehydratase
D0808_16705	COG4492	Belongs to the UPF0735 family
D0808_16710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D0808_16715	COG3290	protein histidine kinase activity
D0808_16720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D0808_16725	COG2868	ribosomal protein
D0808_16730	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D0808_16735	COG1994	Peptidase M50
D0808_16740	COG0739	heme binding
D0808_16745	COG2894	cell division
D0808_16750	COG0850	regulation of cytokinetic process
D0808_16755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D0808_16760	COG1792	Involved in formation and maintenance of cell shape
D0808_16765	COG1077	Cell shape determining protein MreB Mrl
D0808_16770	COG2003	Belongs to the UPF0758 family
D0808_16775	COG0424	maF-like protein
D0808_16785	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D0808_16790	COG0285	dihydrofolate synthase activity
D0808_16795	COG0525	valine-tRNA ligase activity
D0808_16805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0808_16810	COG1388	LysM domain
D0808_16815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D0808_16820	COG0113	porphobilinogen synthase activity
D0808_16825	COG1587	Uroporphyrinogen-III synthase
D0808_16830	COG0181	hydroxymethylbilane synthase activity
D0808_16835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0808_16840	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D0808_16850	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D0808_16855	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D0808_16860	COG0470	DNA polymerase III
D0808_16860	COG1067	ATP-dependent peptidase activity
D0808_16865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D0808_16870	COG0544	peptidyl-prolyl cis-trans isomerase activity
D0808_16875	COG1477	protein flavinylation
D0808_16875	COG0457	Tetratricopeptide repeat
D0808_16880	COG0066	3-isopropylmalate dehydratase activity
D0808_16885	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D0808_16890	COG0473	3-isopropylmalate dehydrogenase activity
D0808_16895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D0808_16900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D0808_16905	COG0440	acetolactate synthase activity
D0808_16910	COG0028	Belongs to the TPP enzyme family
D0808_16925	COG0454	-acetyltransferase
D0808_16935	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D0808_16945	COG0622	Phosphoesterase
D0808_16950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D0808_16955	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D0808_16960	COG5401	PFAM Sporulation and spore germination
D0808_16965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D0808_16970	COG1846	Transcriptional regulator
D0808_16975	COG2197	response regulator
D0808_16980	COG0824	Thioesterase
D0808_16985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D0808_16990	COG1053	succinate dehydrogenase
D0808_16995	COG2009	succinate dehydrogenase
D0808_17000	COG1719	4-vinyl reductase, 4VR
D0808_17005	COG0527	aspartate kinase activity
D0808_17015	COG0322	excinuclease ABC activity
D0808_17020	COG3118	belongs to the thioredoxin family
D0808_17030	COG3534	alpha-L-arabinofuranosidase
D0808_17035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D0808_17040	COG2086	electron transfer activity
D0808_17045	COG1024	Enoyl-CoA hydratase
D0808_17050	COG1309	transcriptional regulator
D0808_17055	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_17060	COG3766	membrane
D0808_17065	COG1193	negative regulation of DNA recombination
D0808_17070	COG1796	DNA polymerase
D0808_17070	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D0808_17075	COG1286	toxin biosynthetic process
D0808_17080	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D0808_17085	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D0808_17090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0808_17090	COG0072	phenylalanine-tRNA ligase activity
D0808_17095	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D0808_17105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0808_17115	COG3835	regulator
D0808_17120	COG0277	FAD linked oxidase domain protein
D0808_17125	COG0247	lactate metabolic process
D0808_17130	COG0346	lactoylglutathione lyase activity
D0808_17135	COG1966	Carbon starvation protein
D0808_17140	COG3534	alpha-L-arabinofuranosidase
D0808_17145	COG0395	ABC-type sugar transport system, permease component
D0808_17150	COG1175	transmembrane transport
D0808_17155	COG1653	transport
D0808_17160	COG0371	Dehydrogenase
D0808_17165	COG0647	UMP catabolic process
D0808_17170	COG0235	Class ii aldolase
D0808_17175	COG1069	ribulokinase activity
D0808_17180	COG2160	L-arabinose isomerase activity
D0808_17185	COG3507	Belongs to the glycosyl hydrolase 43 family
D0808_17190	COG1363	Peptidase, m42
D0808_17200	COG3326	Membrane
D0808_17205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D0808_17210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D0808_17215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D0808_17225	COG1346	cytolysis
D0808_17230	COG1380	Effector of murein hydrolase LrgA
D0808_17235	COG3279	Response regulator of the LytR AlgR family
D0808_17240	COG3275	phosphorelay sensor kinase activity
D0808_17250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D0808_17260	COG0398	Pfam SNARE associated Golgi protein
D0808_17265	COG1484	DNA-dependent DNA replication
D0808_17270	COG3611	Membrane attachment protein
D0808_17275	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D0808_17280	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D0808_17285	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0808_17290	COG1733	regulation of RNA biosynthetic process
D0808_17295	COG2814	Major facilitator Superfamily
D0808_17300	COG0656	L-ascorbic acid biosynthetic process
D0808_17305	COG0237	dephospho-CoA kinase activity
D0808_17310	COG1971	Probably functions as a manganese efflux pump
D0808_17315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D0808_17320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0808_17320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0808_17325	COG5002	protein histidine kinase activity
D0808_17330	COG0745	RESPONSE REGULATOR receiver
D0808_17335	COG0039	L-malate dehydrogenase activity
D0808_17340	COG0538	isocitrate dehydrogenase activity
D0808_17345	COG0372	Belongs to the citrate synthase family
D0808_17350	COG2707	UPF0756 membrane protein
D0808_17355	COG0628	permease
D0808_17360	COG3030	protein affecting phage T7 exclusion by the F plasmid
D0808_17365	COG0469	pyruvate kinase activity
D0808_17370	COG0205	6-phosphofructokinase activity
D0808_17375	COG0825	malonyl-CoA metabolic process
D0808_17380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D0808_17385	COG0281	malic enzyme
D0808_17390	COG0587	DNA-directed DNA polymerase activity
D0808_17410	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D0808_17420	COG4109	DRTGG domain
D0808_17425	COG0730	response to heat
D0808_17430	COG1473	amidohydrolase
D0808_17435	COG0196	riboflavin kinase activity
D0808_17440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_17445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D0808_17450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_17455	COG1126	abc transporter atp-binding protein
D0808_17460	COG0765	amino acid transport
D0808_17465	COG0765	amino acid transport
D0808_17470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_17475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_17480	COG0454	-acetyltransferase
D0808_17485	COG0583	DNA-binding transcription factor activity
D0808_17490	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D0808_17495	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_17505	COG0165	Argininosuccinate lyase
D0808_17510	COG0137	argininosuccinate synthase activity
D0808_17515	COG0521	Mo-molybdopterin cofactor biosynthetic process
D0808_17520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D0808_17525	COG0827	DNA restriction-modification system
D0808_17530	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D0808_17535	COG3874	Sporulation protein YtfJ
D0808_17545	COG1714	RDD family
D0808_17550	COG0616	signal peptide processing
D0808_17555	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D0808_17560	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D0808_17565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0808_17575	COG0301	tRNA thio-modification
D0808_17580	COG1104	cysteine desulfurase activity
D0808_17585	COG1114	Component of the transport system for branched-chain amino acids
D0808_17590	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D0808_17595	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D0808_17600	COG1309	transcriptional regulator
D0808_17605	COG1956	GAF domain-containing protein
D0808_17610	COG2199	diguanylate cyclase activity
D0808_17610	COG2203	Gaf domain
D0808_17620	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D0808_17625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0808_17635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0808_17640	COG0454	-acetyltransferase
D0808_17645	COG0517	IMP dehydrogenase activity
D0808_17650	COG0123	including yeast histone deacetylase and acetoin utilization protein
D0808_17655	COG1360	Flagellar Motor Protein
D0808_17660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0808_17665	COG1609	Transcriptional regulator
D0808_17670	COG1605	Chorismate mutase
D0808_17670	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D0808_17675	COG3118	belongs to the thioredoxin family
D0808_17680	COG4980	gas vesicle protein
D0808_17685	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D0808_17690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D0808_17695	COG1674	ftsk spoiiie
D0808_17700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0808_17705	COG4848	Belongs to the UPF0354 family
D0808_17710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_17720	COG1363	Peptidase, m42
D0808_17725	COG5584	Small secreted protein
D0808_17730	COG0281	malic enzyme
D0808_17735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_17740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D0808_17750	COG0510	thiamine kinase activity
D0808_17755	COG1523	belongs to the glycosyl hydrolase 13 family
D0808_17760	COG1597	lipid kinase activity
D0808_17770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D0808_17775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0808_17780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0808_17785	COG2252	PERMEase
D0808_17790	COG4473	ABC transporter
D0808_17795	COG1131	(ABC) transporter
D0808_17800	COG1349	DNA-binding transcription factor activity
D0808_17805	COG1187	pseudouridine synthase activity
D0808_17810	COG2244	polysaccharide biosynthetic process
D0808_17815	COG2081	HI0933 family
D0808_17820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0808_17830	COG5578	integral membrane protein
D0808_17835	COG0673	inositol 2-dehydrogenase activity
D0808_17840	COG1653	transport
D0808_17845	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D0808_17850	COG4209	transmembrane transport
D0808_17855	COG2207	Transcriptional regulator
D0808_17860	COG1653	transport
D0808_17865	COG0395	ABC-type sugar transport system, permease component
D0808_17870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0808_17875	COG2124	cytochrome p450
D0808_17880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D0808_17890	COG0156	8-amino-7-oxononanoate synthase activity
D0808_17895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0808_17905	COG1073	alpha beta
D0808_17930	COG1486	melibiose metabolic process
D0808_17935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0808_17940	COG0495	leucyl-tRNA aminoacylation
D0808_17950	COG2202	Pas domain
D0808_17950	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_17955	COG2814	Major facilitator Superfamily
D0808_17960	COG2433	Pfam Transposase IS66
D0808_17965	COG0577	efflux transmembrane transporter activity
D0808_17970	COG1136	(ABC) transporter
D0808_17975	COG2205	protein histidine kinase activity
D0808_17980	COG0745	RESPONSE REGULATOR receiver
D0808_17985	COG0577	efflux transmembrane transporter activity
D0808_17990	COG1136	(ABC) transporter
D0808_18005	COG1131	(ABC) transporter
D0808_18010	COG1725	Transcriptional regulator
D0808_18020	COG1242	4 iron, 4 sulfur cluster binding
D0808_18025	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D0808_18035	COG2267	carboxylic ester hydrolase activity
D0808_18040	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D0808_18045	COG1113	amino acid transport
D0808_18050	COG0367	asparagine synthase
D0808_18055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D0808_18060	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D0808_18070	COG1506	peptidase
D0808_18075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D0808_18080	COG1116	anion transmembrane transporter activity
D0808_18085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D0808_18090	COG0494	nUDIX hydrolase
D0808_18095	COG4824	toxin secretion phage lysis holin
D0808_18100	COG0783	Belongs to the Dps family
D0808_18115	COG1854	S-ribosylhomocysteine lyase activity
D0808_18120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D0808_18125	COG0288	reversible hydration of carbon dioxide
D0808_18130	COG0254	rRNA binding
D0808_18135	COG1271	oxidase subunit
D0808_18140	COG1294	oxidase, subunit
D0808_18150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0808_18155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0808_18155	COG1321	iron dependent repressor
D0808_18160	COG1121	(ABC) transporter
D0808_18165	COG0803	Belongs to the bacterial solute-binding protein 9 family
D0808_18170	COG4948	Mandelate Racemase Muconate Lactonizing
D0808_18175	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_18180	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D0808_18185	COG0596	Alpha beta hydrolase
D0808_18190	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D0808_18195	COG1169	isochorismate synthase
D0808_18205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0808_18210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0808_18215	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D0808_18220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0808_18225	COG0438	transferase activity, transferring glycosyl groups
D0808_18235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0808_18240	COG0438	transferase activity, transferring glycosyl groups
D0808_18245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0808_18250	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D0808_18255	COG0058	SHG alpha-glucan phosphorylase activity
D0808_18260	COG0297	glycogen (starch) synthase activity
D0808_18265	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0808_18270	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0808_18275	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D0808_18400	COG3859	Proton-coupled thiamine transporter YuaJ
D0808_18405	COG1247	-acetyltransferase
D0808_18410	COG2268	Band 7 protein
D0808_18415	COG1585	Membrane protein implicated in regulation of membrane protease activity
D0808_18420	COG2318	DinB family
D0808_18430	COG1454	alcohol dehydrogenase
D0808_18440	COG1510	regulation of RNA biosynthetic process
D0808_18450	COG0569	domain protein
D0808_18455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0808_18460	COG4682	membrane
D0808_18465	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0808_18470	COG0477	Major facilitator Superfamily
D0808_18475	COG5553	Cysteine dioxygenase type I
D0808_18485	COG1968	undecaprenyl-diphosphatase activity
D0808_18490	COG0628	permease
D0808_18495	COG0673	inositol 2-dehydrogenase activity
D0808_18500	COG4806	L-rhamnose isomerase
D0808_18505	COG3254	rhamnose metabolic process
D0808_18510	COG1070	Carbohydrate kinase
D0808_18515	COG1349	DNA-binding transcription factor activity
D0808_18520	COG3347	Dehydrogenase
D0808_18520	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_18530	COG0840	transmembrane signaling receptor activity
D0808_18535	COG0840	transmembrane signaling receptor activity
D0808_18540	COG0840	transmembrane signaling receptor activity
D0808_18545	COG0840	transmembrane signaling receptor activity
D0808_18560	COG0432	Pfam Uncharacterised protein family UPF0047
D0808_18565	COG0366	Alpha amylase catalytic
D0808_18570	COG1253	flavin adenine dinucleotide binding
D0808_18575	COG2738	Putative neutral zinc metallopeptidase
D0808_18590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D0808_18605	COG0166	Belongs to the GPI family
D0808_18610	COG1979	alcohol dehydrogenase
D0808_18615	COG1979	alcohol dehydrogenase
D0808_18620	COG2155	Conserved Protein
D0808_18625	COG1098	S1 RNA binding domain
D0808_18630	COG0436	Aminotransferase
D0808_18635	COG1522	sequence-specific DNA binding
D0808_18640	COG2267	carboxylic ester hydrolase activity
D0808_18650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D0808_18655	COG2205	protein histidine kinase activity
D0808_18665	COG5018	Exonuclease
D0808_18675	COG2814	Major facilitator Superfamily
D0808_18680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0808_18685	COG3011	Protein conserved in bacteria
D0808_18695	COG3290	protein histidine kinase activity
D0808_18700	COG4565	transcriptional regulatory protein
D0808_18725	COG3493	citrate carrier protein
D0808_18735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D0808_18735	COG2111	Na H antiporter
D0808_18740	COG2111	Na H antiporter
D0808_18745	COG1006	Multisubunit Na H antiporter MnhC subunit
D0808_18750	COG0651	ATP synthesis coupled electron transport
D0808_18755	COG1863	multisubunit Na H antiporter MnhE subunit
D0808_18760	COG2212	antiporter activity
D0808_18765	COG1320	monovalent cation:proton antiporter activity
D0808_18770	COG2050	protein possibly involved in aromatic compounds catabolism
D0808_18775	COG2197	response regulator
D0808_18780	COG4585	Histidine kinase
D0808_18790	COG0142	geranyltranstransferase activity
D0808_18805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D0808_18810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D0808_18815	COG1335	isochorismatase
D0808_18820	COG5506	Protein of unknown function (DUF1694)
D0808_18835	COG0628	permease
D0808_18850	COG1418	mRNA catabolic process
D0808_18855	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_18865	COG1511	domain protein
D0808_18870	COG0433	COG0433 Predicted ATPase
D0808_18870	COG1674	ftsk spoiiie
D0808_18875	COG4499	WXG100 protein secretion system (Wss), protein YukC
D0808_18880	COG5417	Belongs to the EsaB family
D0808_18885	COG4842	Belongs to the WXG100 family
D0808_18895	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D0808_18895	COG2508	Transcriptional regulator
D0808_18900	COG0686	Belongs to the AlaDH PNT family
D0808_18905	COG5634	Uncharacterized conserved protein (DUF2278)
D0808_18910	COG3251	PFAM MbtH domain protein
D0808_18915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_18920	COG3433	isochorismatase activity
D0808_18920	COG1535	isochorismatase
D0808_18925	COG1021	2,3-dihydroxybenzoate-AMP ligase
D0808_18930	COG1169	isochorismate synthase
D0808_18935	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_18940	COG2819	hydrolase of the alpha beta superfamily
D0808_18945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D0808_18950	COG1268	BioY protein
D0808_18955	COG2056	Na+-H+ antiporter family
D0808_18960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D0808_18965	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D0808_18970	COG3584	3D domain protein
D0808_18985	COG1252	NADH dehydrogenase
D0808_18990	COG0492	ferredoxin-NADP+ reductase activity
D0808_19000	COG0516	GMP reductase activity
D0808_19005	COG2808	Putative FMN-binding domain
D0808_19010	COG0456	acetyltransferase
D0808_19015	COG0316	Belongs to the HesB IscA family
D0808_19020	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D0808_19025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0808_19030	COG4844	belongs to the
D0808_19035	COG1252	NADH dehydrogenase
D0808_19040	COG4837	Protein of unknown function (DUF1462)
D0808_19045	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D0808_19050	COG0823	Involved in the tonB-independent uptake of proteins
D0808_19050	COG1506	peptidase
D0808_19050	COG4946	Tricorn protease homolog
D0808_19055	COG0083	homoserine kinase activity
D0808_19060	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D0808_19065	COG0460	homoserine dehydrogenase
D0808_19070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0808_19075	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0808_19080	COG0647	UMP catabolic process
D0808_19085	COG2445	Protein of unknown function DUF86
D0808_19090	COG4470	Protein conserved in bacteria
D0808_19100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D0808_19105	COG0739	heme binding
D0808_19115	COG3377	Domain of unknown function (DUF1805)
D0808_19120	COG0737	Belongs to the 5'-nucleotidase family
D0808_19125	COG0730	response to heat
D0808_19130	COG1801	Protein of unknown function DUF72
D0808_19140	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D0808_19145	COG2508	Transcriptional regulator
D0808_19150	COG2233	PERMEase
D0808_19155	COG2233	PERMEase
D0808_19160	COG3648	Uricase
D0808_19160	COG3195	allantoin biosynthetic process
D0808_19165	COG2351	hydroxyisourate hydrolase activity
D0808_19180	COG2080	2 iron, 2 sulfur cluster binding
D0808_19185	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D0808_19190	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D0808_19195	COG2068	MobA-Related Protein
D0808_19200	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D0808_19205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D0808_19210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0808_19215	COG2356	endonuclease I
D0808_19220	COG3842	ATPase activity
D0808_19225	COG2188	Transcriptional regulator
D0808_19230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0808_19235	COG0395	ABC-type sugar transport system, permease component
D0808_19240	COG1175	transmembrane transport
D0808_19245	COG1653	transport
D0808_19250	COG2222	sugar isomerase
D0808_19255	COG0322	excinuclease ABC activity
D0808_19260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0808_19275	COG0346	lactoylglutathione lyase activity
D0808_19280	COG0640	Transcriptional regulator
D0808_19285	COG0719	Fe-S assembly protein
D0808_19290	COG0822	iron-sulfur transferase activity
D0808_19295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0808_19300	COG0719	Fe-S assembly protein
D0808_19305	COG0396	ATPase activity
D0808_19320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D0808_19325	COG1464	Belongs to the NlpA lipoprotein family
D0808_19330	COG2011	ABC-type metal ion transport system permease component
D0808_19335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D0808_19345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_19350	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D0808_19360	COG0509	glycine decarboxylation via glycine cleavage system
D0808_19365	COG1393	Belongs to the ArsC family
D0808_19370	COG1960	acyl-CoA dehydrogenase activity
D0808_19375	COG0183	Belongs to the thiolase family
D0808_19380	COG1250	3-hydroxyacyl-CoA dehydrogenase
D0808_19380	COG1024	Enoyl-CoA hydratase
D0808_19400	COG5577	PFAM Coat F domain
D0808_19410	COG0477	Major facilitator Superfamily
D0808_19415	COG1942	4-Oxalocrotonate Tautomerase
D0808_19420	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_19425	COG0583	DNA-binding transcription factor activity
D0808_19435	COG1120	ATPase activity
D0808_19450	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_19455	COG0783	Belongs to the Dps family
D0808_19460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0808_19465	COG0745	RESPONSE REGULATOR receiver
D0808_19470	COG2205	protein histidine kinase activity
D0808_19470	COG2770	Histidine kinase
D0808_19480	COG1309	transcriptional regulator
D0808_19485	COG0114	fumarate hydratase activity
D0808_19495	COG0697	spore germination
D0808_19500	COG0814	amino acid
D0808_19510	COG2197	response regulator
D0808_19515	COG4585	Histidine kinase
D0808_19520	COG4758	membrane
D0808_19525	COG3595	metallopeptidase activity
D0808_19530	COG1842	Phage shock protein A
D0808_19535	COG4758	membrane
D0808_19540	COG2814	Major facilitator Superfamily
D0808_19545	COG2096	Adenosyltransferase
D0808_19550	COG1120	ATPase activity
D0808_19555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_19560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_19565	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_19570	COG3386	PFAM SMP-30 Gluconolaconase
D0808_19575	COG2205	protein histidine kinase activity
D0808_19580	COG0745	RESPONSE REGULATOR receiver
D0808_19590	COG1191	sigma factor activity
D0808_19600	COG2140	Oxalate decarboxylase
D0808_19610	COG0577	efflux transmembrane transporter activity
D0808_19615	COG1136	(ABC) transporter
D0808_19620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0808_19625	COG1120	ATPase activity
D0808_19630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_19635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_19640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_19650	COG0531	amino acid
D0808_19665	COG1988	membrane-bound metal-dependent
D0808_19670	COG1368	sulfuric ester hydrolase activity
D0808_19675	COG1910	domain protein
D0808_19680	COG0725	ABC transporter, periplasmic molybdate-binding protein
D0808_19685	COG4149	molybdate abc transporter
D0808_19690	COG0656	L-ascorbic acid biosynthetic process
D0808_19700	COG0025	NhaP-type Na H and K H
D0808_19705	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0808_19710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0808_19715	COG3973	AAA domain
D0808_19725	COG2860	membrane
D0808_19730	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D0808_19735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0808_19740	COG2217	Heavy metal translocating P-type atpase
D0808_19745	COG2217	Heavy metal translocating P-type atpase
D0808_19750	COG2608	mercury ion transmembrane transporter activity
D0808_19755	COG1937	Protein conserved in bacteria
D0808_19760	COG0673	inositol 2-dehydrogenase activity
D0808_19765	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D0808_19770	COG1289	transmembrane transporter activity
D0808_19780	COG2076	Multidrug Resistance protein
D0808_19785	COG1309	transcriptional regulator
D0808_19790	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_19800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D0808_19805	COG0557	exoribonuclease II activity
D0808_19810	COG1647	Serine aminopeptidase, S33
D0808_19815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0808_19820	COG0596	Alpha beta hydrolase
D0808_19825	COG1476	TRANSCRIPTIONal
D0808_19830	COG1396	sequence-specific DNA binding
D0808_19835	COG1396	sequence-specific DNA binding
D0808_19840	COG1733	regulation of RNA biosynthetic process
D0808_19845	COG0840	transmembrane signaling receptor activity
D0808_19850	COG1174	glycine betaine transport
D0808_19855	COG1732	Glycine betaine
D0808_19860	COG1174	glycine betaine transport
D0808_19865	COG1125	glycine betaine transport
D0808_19865	COG0517	IMP dehydrogenase activity
D0808_19870	COG1510	regulation of RNA biosynthetic process
D0808_19875	COG1174	glycine betaine transport
D0808_19880	COG1732	Glycine betaine
D0808_19885	COG1174	glycine betaine transport
D0808_19890	COG0517	IMP dehydrogenase activity
D0808_19890	COG1125	glycine betaine transport
D0808_19895	COG1510	regulation of RNA biosynthetic process
D0808_19900	COG2095	MarC family integral membrane protein
D0808_19910	COG3064	Membrane
D0808_19915	COG4640	response to antibiotic
D0808_19920	COG0456	acetyltransferase
D0808_19925	COG0148	phosphopyruvate hydratase activity
D0808_19930	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D0808_19935	COG0149	triose-phosphate isomerase activity
D0808_19940	COG0126	phosphoglycerate kinase activity
D0808_19945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0808_19950	COG2390	Transcriptional regulator
D0808_19955	COG2814	Major facilitator Superfamily
D0808_19960	COG1609	Transcriptional regulator
D0808_19965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_19975	COG0583	DNA-binding transcription factor activity
D0808_19980	COG0697	spore germination
D0808_19985	COG1113	amino acid transport
D0808_19990	COG3858	chitin binding
D0808_19995	COG1556	Lactate utilization protein
D0808_20000	COG1139	Iron-sulfur cluster binding protein
D0808_20005	COG0247	lactate metabolic process
D0808_20010	COG2197	response regulator
D0808_20015	COG4585	Histidine kinase
D0808_20020	COG0842	Transport permease protein
D0808_20025	COG1131	(ABC) transporter
D0808_20030	COG0596	Alpha beta hydrolase
D0808_20035	COG2208	phosphoserine phosphatase activity
D0808_20040	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D0808_20045	COG1874	Beta-galactosidase
D0808_20050	COG3833	ABC-type maltose transport systems, permease component
D0808_20055	COG1175	transmembrane transport
D0808_20060	COG2182	Extracellular solute-binding protein
D0808_20065	COG1609	Transcriptional regulator
D0808_20070	COG2186	Transcriptional regulator
D0808_20075	COG1620	l-lactate permease
D0808_20080	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D0808_20090	COG5039	Polysaccharide pyruvyl transferase
D0808_20095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0808_20100	COG0110	maltose O-acetyltransferase activity
D0808_20105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0808_20110	COG2244	polysaccharide biosynthetic process
D0808_20115	COG1216	Glycosyl transferase, family 2
D0808_20120	COG5039	Polysaccharide pyruvyl transferase
D0808_20125	COG1216	Glycosyl transferase, family 2
D0808_20135	COG0438	transferase activity, transferring glycosyl groups
D0808_20140	COG1215	transferase activity, transferring glycosyl groups
D0808_20145	COG0438	transferase activity, transferring glycosyl groups
D0808_20150	COG1086	Polysaccharide biosynthesis protein
D0808_20155	COG0489	protein tyrosine kinase activity
D0808_20160	COG3944	biosynthesis protein
D0808_20165	COG1396	sequence-specific DNA binding
D0808_20170	COG2272	Belongs to the type-B carboxylesterase lipase family
D0808_20180	COG3479	Phenolic acid decarboxylase
D0808_20190	COG1794	racemase activity, acting on amino acids and derivatives
D0808_20195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0808_20205	COG1621	beta-fructofuranosidase activity
D0808_20210	COG1621	beta-fructofuranosidase activity
D0808_20215	COG0531	amino acid
D0808_20220	COG1309	transcriptional regulator
D0808_20225	COG2076	Multidrug Resistance protein
D0808_20230	COG2076	Multidrug Resistance protein
D0808_20240	COG3621	Patatin-like phospholipase
D0808_20250	COG0740	serine-type endopeptidase activity
D0808_20255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0808_20260	COG0366	Alpha amylase catalytic
D0808_20265	COG1554	hydrolase, family 65, central catalytic
D0808_20270	COG5521	maltodextrose utilization protein MalA
D0808_20275	COG3833	ABC-type maltose transport systems, permease component
D0808_20280	COG1175	transmembrane transport
D0808_20285	COG2182	Extracellular solute-binding protein
D0808_20290	COG0366	Alpha amylase catalytic
D0808_20295	COG1609	Transcriptional regulator
D0808_20300	COG1611	Belongs to the LOG family
D0808_20305	COG1694	Mazg nucleotide pyrophosphohydrolase
D0808_20310	COG0659	secondary active sulfate transmembrane transporter activity
D0808_20315	COG0288	reversible hydration of carbon dioxide
D0808_20325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0808_20330	COG0577	efflux transmembrane transporter activity
D0808_20335	COG1136	(ABC) transporter
D0808_20340	COG5002	protein histidine kinase activity
D0808_20345	COG0745	RESPONSE REGULATOR receiver
D0808_20355	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D0808_20360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_20365	COG1481	regulation of sporulation
D0808_20370	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D0808_20375	COG1660	Displays ATPase and GTPase activities
D0808_20380	COG1051	belongs to the nudix hydrolase family
D0808_20385	COG0492	ferredoxin-NADP+ reductase activity
D0808_20390	COG3883	PFAM NLP P60 protein
D0808_20390	COG0791	NLP P60 protein
D0808_20395	COG0457	Tetratricopeptide repeat
D0808_20400	COG1132	(ABC) transporter
D0808_20435	COG0140	phosphoribosyl-ATP diphosphatase activity
D0808_20435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D0808_20440	COG0107	imidazoleglycerol-phosphate synthase activity
D0808_20445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D0808_20450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D0808_20455	COG0131	Imidazoleglycerol-phosphate dehydratase
D0808_20460	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D0808_20465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D0808_20470	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D0808_20475	COG4990	cell redox homeostasis
D0808_20480	COG5297	Belongs to the glycosyl hydrolase family 6
D0808_20485	COG0110	maltose O-acetyltransferase activity
D0808_20490	COG0546	phosphoglycolate phosphatase activity
D0808_20495	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D0808_20500	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D0808_20505	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D0808_20510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D0808_20515	COG0363	glucosamine-6-phosphate deaminase activity
D0808_20525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D0808_20530	COG1950	PFAM Membrane protein of
D0808_20535	COG1983	PspC domain protein
D0808_20540	COG3595	metallopeptidase activity
D0808_20555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0808_20560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D0808_20565	COG0556	nucleotide-excision repair
D0808_20570	COG4897	Protein conserved in bacteria
D0808_20575	COG3848	Pyruvate phosphate dikinase
D0808_20575	COG0574	Belongs to the PEP-utilizing enzyme family
D0808_20580	COG1309	transcriptional regulator
D0808_20585	COG2814	Major facilitator Superfamily
D0808_20590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0808_20600	COG3409	Peptidoglycan-binding domain 1 protein
D0808_20600	COG0793	Belongs to the peptidase S41A family
D0808_20605	COG2177	Part of the ABC transporter FtsEX involved in
D0808_20610	COG2884	Cell division ATP-binding protein ftsE
D0808_20615	COG2010	Cytochrome c
D0808_20620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_20630	COG0653	protein targeting
D0808_20635	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D0808_20650	COG1516	flagellar protein fliS
D0808_20655	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D0808_20660	COG1334	flagellar protein FlaG
D0808_20665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0808_20670	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D0808_20675	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D0808_20685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0808_20690	COG1256	bacterial-type flagellum assembly
D0808_20690	COG4786	Flagellar basal body rod
D0808_20695	COG3418	PFAM FlgN family protein
D0808_20700	COG2747	anti-sigma28 factor FlgM
D0808_20710	COG1040	competence protein
D0808_20720	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D0808_20725	COG1307	EDD domain protein, DegV family
D0808_20730	COG2197	response regulator
D0808_20735	COG4585	Histidine kinase
D0808_20740	COG1739	Uncharacterized protein family UPF0029
D0808_20745	COG1316	TRANSCRIPTIONal
D0808_20750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D0808_20755	COG0438	transferase activity, transferring glycosyl groups
D0808_20760	COG1215	transferase activity, transferring glycosyl groups
D0808_20765	COG3206	protein involved in exopolysaccharide biosynthesis
D0808_20770	COG3307	-O-antigen
D0808_20775	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D0808_20780	COG0438	transferase activity, transferring glycosyl groups
D0808_20780	COG0297	glycogen (starch) synthase activity
D0808_20785	COG2244	polysaccharide biosynthetic process
D0808_20795	COG2247	cell wall binding repeat
D0808_20795	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_20800	COG2247	cell wall binding repeat
D0808_20800	COG2385	sporulation resulting in formation of a cellular spore
D0808_20810	COG1316	TRANSCRIPTIONal
D0808_20815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D0808_20820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0808_20840	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D0808_20840	COG1215	transferase activity, transferring glycosyl groups
D0808_20845	COG0463	Glycosyl transferase, family 2
D0808_20860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0808_20865	COG1134	teichoic acid transport
D0808_20870	COG1682	transport, permease protein
D0808_20875	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D0808_20880	COG0438	transferase activity, transferring glycosyl groups
D0808_20885	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D0808_20890	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D0808_20895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D0808_20905	COG4193	domain, Protein
D0808_20910	COG1482	cell wall glycoprotein biosynthetic process
D0808_20915	COG0697	spore germination
D0808_20920	COG0814	amino acid
D0808_20930	COG2814	Major facilitator Superfamily
D0808_20935	COG1316	TRANSCRIPTIONal
D0808_20940	COG0561	phosphatase activity
D0808_20945	COG0791	NLP P60 protein
D0808_20955	COG2843	Capsule synthesis protein
D0808_20965	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D0808_20975	COG1609	Transcriptional regulator
D0808_20980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0808_20985	COG1869	D-ribose catabolic process
D0808_20990	COG1129	ABC transporter
D0808_20995	COG1172	Belongs to the binding-protein-dependent transport system permease family
D0808_21000	COG1879	ABC-type sugar transport system periplasmic component
D0808_21005	COG3103	Sh3 type 3 domain protein
D0808_21015	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0808_21020	COG3527	Alpha-acetolactate decarboxylase
D0808_21025	COG0028	Belongs to the TPP enzyme family
D0808_21030	COG0583	DNA-binding transcription factor activity
D0808_21035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D0808_21050	COG5337	Spore coat protein CotH