locus-tag class description BAX60_00090 ENOG4108PNI recT protein BAX60_00095 ENOG4108NF7 phage-type endonuclease BAX60_00160 ENOG410635T phage-like element pbsx protein BAX60_00165 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BAX60_00175 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAX60_00185 ENOG4105EE0 oxidoreductase BAX60_00190 ENOG4105DKG l-rhamnose isomerase BAX60_00195 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) BAX60_00200 ENOG4105DET Rhamnulokinase BAX60_00205 ENOG4105E98 transcriptional regulator DeoR family BAX60_00215 ENOG4105C8Q Methyl-accepting chemotaxis BAX60_00220 ENOG4105C8Q Methyl-accepting chemotaxis BAX60_00225 ENOG4105C8Q Methyl-accepting chemotaxis BAX60_00230 ENOG4105C8Q Methyl-accepting chemotaxis BAX60_00245 ENOG4105EA8 2-Nitropropane dioxygenase BAX60_00250 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme BAX60_00260 ENOG4105C37 (CBS) domain BAX60_00275 ENOG4107PBV potassium channel BAX60_00280 ENOG4107PBV potassium channel BAX60_00295 ENOG4107QYV phosphohexose isomerase BAX60_00305 ENOG4107QW4 alcohol dehydrogenase BAX60_00310 ENOG4105WG9 Conserved Protein BAX60_00320 ENOG4105CHM Aminotransferase BAX60_00325 ENOG4108ZB6 transcriptional regulator AsnC family BAX60_00330 ENOG4108MUZ hydrolase BAX60_00340 ENOG4105C87 Aminotransferase class I and II BAX60_00345 ENOG4108HGU Histidine kinase BAX60_00350 ENOG4105Y38 Kinase-associated protein B BAX60_00370 ENOG4105BZ4 penicillin-binding protein BAX60_00375 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BAX60_00390 ENOG4108MRH transcriptional regulatory protein BAX60_00395 ENOG4105DIH basic membrane BAX60_00400 ENOG4108JQ9 ABC transporter BAX60_00405 ENOG4105UIB (ABC) transporter BAX60_00425 ENOG4105D65 subunit l BAX60_00430 ENOG4105HC0 Na H antiporter BAX60_00435 ENOG4108ZE9 Monovalent cation H antiporter subunit C BAX60_00440 ENOG4108JPZ Monovalent cation H antiporter subunit D BAX60_00445 ENOG4105SC1 monovalent cation H antiporter subunit E BAX60_00455 ENOG4105KJM monovalent cation h antiporter subunit g BAX60_00460 ENOG4105KA0 thioesterase Superfamily protein BAX60_00470 ENOG4105BZU Histidine kinase BAX60_00495 ENOG4105D58 Diguanylate phosphodiesterase BAX60_00500 ENOG4105DAP Nicotinate phosphoribosyltransferase BAX60_00525 ENOG4105C02 permease BAX60_00545 ENOG410904N short-chain dehydrogenase reductase BAX60_00580 ENOG4108K8K Transcriptional regulator BAX60_00585 ENOG4105DCF alanine dehydrogenase BAX60_00595 ENOG4105WQT MbtH domain protein BAX60_00600 ENOG4105CEY Amp-dependent synthetase and ligase BAX60_00605 ENOG4105WQI isochorismatase BAX60_00610 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BAX60_00615 ENOG4105E4F Isochorismate synthase BAX60_00620 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BAX60_00625 ENOG4105NIV Esterase BAX60_00645 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BAX60_00655 ENOG41069ER domain protein BAX60_00670 ENOG4105CEP NADH dehydrogenase BAX60_00675 ENOG4105CAY ferredoxin--nadp reductase BAX60_00695 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BAX60_00705 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BAX60_00720 ENOG4105ZKE UPF0349 protein BAX60_00740 ENOG41083MR nifu domain-containing protein BAX60_00745 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BAX60_00750 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BAX60_00755 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) BAX60_00760 ENOG4105D6E homoserine dehydrogenase BAX60_00770 ENOG4108W5N phosphatidylglycerophosphatase a BAX60_00775 ENOG4105D4U had-superfamily hydrolase, subfamily iia BAX60_00785 ENOG4105MMD transcriptional regulator BAX60_00790 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BAX60_00795 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BAX60_00800 ENOG4105FAA peptidase M23 BAX60_00805 ENOG4108YTE sporulation protein YunB BAX60_00810 ENOG4105KZD Domain of unknown function (DUF1805) BAX60_00815 ENOG4107R8B 5'-nucleotidase BAX60_00825 ENOG4105I3N Conserved Protein BAX60_00835 ENOG4105CD3 dihydroorotase BAX60_00840 ENOG4105G9B Transcriptional regulator BAX60_00855 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) BAX60_00860 ENOG4105VT2 5-hydroxyisourate hydrolase BAX60_00875 ENOG4107YV9 domain protein BAX60_00880 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding BAX60_00895 ENOG4105XRQ Xanthine dehydrogenase accessory factor BAX60_00900 ENOG4105C5R Aminotransferase BAX60_00915 ENOG4108K8S endonuclease I BAX60_00920 ENOG4108IJ9 (ABC) transporter BAX60_00925 ENOG4105FDP GntR family transcriptional regulator BAX60_00930 ENOG4108KPW sugar kinase BAX60_00935 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BAX60_00940 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BAX60_00945 ENOG4105XN3 extracellular solute-binding protein family 1 BAX60_00950 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine BAX60_00955 ENOG4105PKS Excinuclease abc c subunit domain protein BAX60_00960 ENOG4107VFR oxidoreductase BAX60_00975 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BAX60_00980 ENOG4105NPE arsR family transcriptional regulator BAX60_00985 ENOG4105DIW FeS assembly protein SUFB BAX60_00990 ENOG4108UNV SUF system FeS assembly protein, NifU family BAX60_00995 ENOG4105C9B Cysteine desulfurase BAX60_01000 ENOG4105JRK feS assembly protein SufD BAX60_01005 ENOG4105C3K feS assembly ATPase SufC BAX60_01025 ENOG4105D01 (LipO)protein BAX60_01030 ENOG4108UMI ABC transporter, permease BAX60_01035 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAX60_01060 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BAX60_01065 ENOG41080E8 Transcriptional regulator, Spx MgsR family BAX60_01070 ENOG4105C1G acyl-Coa dehydrogenase BAX60_01075 ENOG4105CHU acetyl-coa acetyltransferase BAX60_01105 ENOG41067TZ transcriptional regulator, MarR family BAX60_01110 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAX60_01115 ENOG4105MDS 4-oxalocrotonate tautomerase BAX60_01125 ENOG4105EGI Transcriptional regulator BAX60_01135 ENOG4105E0A ABC, transporter BAX60_01150 ENOG4105E1F short-chain dehydrogenase reductase BAX60_01155 ENOG4105HUF DNA protection during starvation protein BAX60_01160 ENOG4105C0H protease BAX60_01170 ENOG4105F3H Histidine kinase BAX60_01180 ENOG41067SE Tetr family transcriptional regulator BAX60_01185 ENOG4105C9Q fumarate hydratase class II BAX60_01210 ENOG4105WH1 Two component transcriptional regulator luxr family BAX60_01215 ENOG4105ENE Histidine kinase BAX60_01230 ENOG41087YS Phage shock protein A BAX60_01250 ENOG4108WBT adenosyltransferase BAX60_01255 ENOG4105E0A ABC, transporter BAX60_01260 ENOG4105EHG Permease protein BAX60_01265 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BAX60_01270 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAX60_01275 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BAX60_01285 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAX60_01295 ENOG4106DF4 Sigma-70, region 4 BAX60_01305 ENOG4105F0F Oxalate decarboxylase BAX60_01315 ENOG4107RBB ABC transporter, permease BAX60_01320 ENOG4105C19 ABC transporter BAX60_01325 ENOG4108WMK Efflux transporter RND family MFP subunit BAX60_01330 ENOG4105E0A ABC, transporter BAX60_01335 ENOG4105EHG Permease protein BAX60_01340 ENOG4105DQ5 transport system permease protein BAX60_01355 ENOG4105D5Q Arginine ornithine antiporter BAX60_01365 ENOG4107K5X Membrane-bound metal-dependent hydrolase BAX60_01370 ENOG4107QZ2 Sulfatase BAX60_01375 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BAX60_01380 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAX60_01385 ENOG4105E0C molybdate abc transporter BAX60_01400 ENOG4105EEQ Na H antiporter BAX60_01405 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BAX60_01410 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAX60_01415 ENOG4105EEM helicase BAX60_01420 ENOG4105EN6 Membrane BAX60_01430 ENOG4107ZQN disulfide bond BAX60_01435 ENOG4105C59 p-type ATPase BAX60_01440 ENOG4105C59 p-type ATPase BAX60_01445 ENOG410681U heavy metal transport detoxification protein BAX60_01450 ENOG4105VPX protein, conserved in bacteria BAX60_01455 ENOG4105D9R oxidoreductase BAX60_01460 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAX60_01465 ENOG4105ME7 Membrane BAX60_01470 ENOG4105DRR Transcriptional regulator, GntR family BAX60_01475 ENOG4108UZ3 Transporter BAX60_01480 ENOG4105RXJ BAX60_01485 ENOG4105KPY Small multidrug resistance protein BAX60_01490 ENOG4105KBX Transcriptional regulator, TetR family BAX60_01495 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAX60_01505 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) BAX60_01510 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BAX60_01520 ENOG4105XZU Preprotein translocase, subunit SecG BAX60_01545 ENOG4105KVH Transcriptional regulator BAX60_01550 ENOG4105C8Q Methyl-accepting chemotaxis BAX60_01575 ENOG4105DA5 (ABC) transporter BAX60_01585 ENOG4105R40 Glycine betaine carnitine choline BAX60_01590 ENOG4108HQR Glycine betaine BAX60_01595 ENOG4105E90 ABC transporter BAX60_01600 ENOG4108IJ8 ABC transporter BAX60_01605 ENOG4107HG4 Transcriptional regulator BAX60_01615 ENOG4105DQ6 Transposase BAX60_01620 ENOG4105R40 Glycine betaine carnitine choline BAX60_01625 ENOG4108HQR Glycine betaine BAX60_01630 ENOG4105E90 ABC transporter BAX60_01635 ENOG4108IJ8 ABC transporter BAX60_01640 ENOG4107HG4 Transcriptional regulator BAX60_01660 ENOG4105T65 Membrane-associated protein BAX60_01665 ENOG4108W0I acetyltransferase BAX60_01670 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) BAX60_01675 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BAX60_01680 ENOG4105CP7 Triose-phosphate isomerase BAX60_01685 ENOG4105BZA Phosphoglycerate kinase BAX60_01695 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BAX60_01710 ENOG4105CMD Transcriptional regulator, GntR family BAX60_01720 ENOG4105DEN Luciferase family BAX60_01730 ENOG4105GZI Transcriptional regulator BAX60_01735 ENOG4107RT3 EamA-like transporter family BAX60_01745 ENOG4105VRS hydrolase family 18 BAX60_01750 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BAX60_01755 ENOG4107QR9 Iron-sulfur cluster binding protein BAX60_01760 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAX60_01780 ENOG4105BZU Histidine kinase BAX60_01785 ENOG4105KCT ABC transporter BAX60_01790 ENOG4108M15 ABC transporter BAX60_01795 ENOG4107R6F Alpha Beta Hydrolase Fold protein BAX60_01800 ENOG4108MJI response regulator BAX60_01815 ENOG4105EG2 ABC transporter, permease BAX60_01825 ENOG4107FKK extracellular solute-binding protein family 1 BAX60_01835 ENOG4105JXH GntR family transcriptional regulator BAX60_01840 ENOG4105DAA L-lactate BAX60_01845 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAX60_01855 ENOG4108ZPC Polysaccharide pyruvyl transferase BAX60_01860 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BAX60_01865 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family BAX60_01870 ENOG4105D3Q Sugar transferase BAX60_01880 ENOG4105K64 Glycosyl transferase, family 2 BAX60_01890 ENOG4107QRS glycosyltransferase group 2 family protein BAX60_01895 ENOG41068W6 Capsular polysaccharide biosynthesis protein BAX60_01900 ENOG4108KMV Glycosyl transferase (Group 1 BAX60_01905 ENOG4105K64 Glycosyl transferase, family 2 BAX60_01910 ENOG4108PQP glycosyl transferase group 1 BAX60_01920 ENOG4108QV3 biosynthesis protein BAX60_01925 ENOG4105HTX biosynthesis protein BAX60_01945 ENOG4105PY6 Phenolic acid decarboxylase BAX60_01950 ENOG4105NI3 Protein of unknown function (DUF3237) BAX60_01960 ENOG4105FQP Beta-lactamase BAX60_01970 ENOG4105EDQ levansucrase EC 2.4.1.10 BAX60_01975 ENOG4108HKT sucrose-6-phosphate hydrolase BAX60_01985 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BAX60_02025 ENOG4105BZ1 (ABC) transporter BAX60_02065 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BAX60_02070 ENOG4105DY9 regulatoR BAX60_02075 ENOG4107QTZ amino acid BAX60_02105 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAX60_02110 ENOG4107URF beta-phospho-glucomutase BAX60_02115 ENOG4105CG3 alpha amylase, catalytic region BAX60_02130 ENOG4105EG2 ABC transporter, permease BAX60_02135 ENOG4105D56 permease protein BAX60_02140 ENOG4107FKK extracellular solute-binding protein family 1 BAX60_02145 ENOG4108IUK alpha amylase, catalytic BAX60_02150 ENOG4105FKQ transcriptional regulator BAX60_02155 ENOG4108URH decarboxylase BAX60_02160 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain BAX60_02165 ENOG4105CHH sulfate transporter BAX60_02170 ENOG4108V2W Carbonate dehydratase BAX60_02175 ENOG4105C5I Dehydrogenase BAX60_02185 ENOG4105C19 ABC transporter BAX60_02190 ENOG4105EWM Histidine kinase BAX60_02200 ENOG4107A6P BAX60_02205 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BAX60_02210 ENOG4105KRI phosphocarrier protein (HPr BAX60_02215 ENOG4105CIE May be required for sporulation (By similarity) BAX60_02220 ENOG4105CHW UPF0052 protein BAX60_02225 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BAX60_02230 ENOG4108Z4K mutator MutT protein BAX60_02235 ENOG4105C3M thioredoxin reductase BAX60_02250 ENOG4105BZ1 (ABC) transporter BAX60_02260 ENOG4106FGC BAX60_02270 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BAX60_02275 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BAX60_02280 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BAX60_02285 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BAX60_02290 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BAX60_02295 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BAX60_02300 ENOG4107RN8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BAX60_02305 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) BAX60_02315 ENOG4108E16 pectate lyase BAX60_02320 ENOG4108S4C acetyltransferase BAX60_02325 ENOG4107XGZ Hydrolase BAX60_02330 ENOG4105HKU nucleoside recognition domain-containing protein BAX60_02335 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) BAX60_02340 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) BAX60_02345 ENOG4105CE4 GlcNAc 6-P deacetylase BAX60_02350 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BAX60_02355 ENOG4105FDP GntR family transcriptional regulator BAX60_02360 ENOG41088CQ domain protein BAX60_02370 ENOG4106A3M Cytochrome p-450 BAX60_02375 ENOG410625E BAX60_02390 ENOG41086DT Membrane protein of unknown function BAX60_02395 ENOG41067S9 phage shock protein C, PspC BAX60_02400 ENOG4108PY7 BAX60_02415 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAX60_02420 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BAX60_02440 ENOG4105MKU Transcriptional regulator BAX60_02460 ENOG4105CN1 protease BAX60_02465 ENOG4105CRP Part of the ABC transporter FtsEX involved in BAX60_02470 ENOG4105CAK Cell division ATP-binding protein ftsE BAX60_02485 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BAX60_02490 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BAX60_02500 ENOG4105MS2 ribosomal subunit Interface protein BAX60_02515 ENOG4105MQ3 flagellar protein FliS BAX60_02520 ENOG4107RT6 flagellar hook-associated BAX60_02525 ENOG41083S7 flagellar protein FlaG BAX60_02530 ENOG4105I03 Flagellin BAX60_02535 ENOG41085Y9 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BAX60_02540 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) BAX60_02545 ENOG4105MKD BAX60_02550 ENOG4105DTJ flagellar hook-associated protein BAX60_02555 ENOG4105E1Q flagellar hook-associated protein BAX60_02570 ENOG4105RU3 BAX60_02575 ENOG41081UC Inherit from COG: Competence protein BAX60_02595 ENOG4105WH1 Two component transcriptional regulator luxr family BAX60_02600 ENOG4105BZU Histidine kinase BAX60_02605 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BAX60_02610 ENOG4108KGH TRANSCRIPTIONal BAX60_02615 ENOG4105ESV Glycosyl transferase, family 4 BAX60_02620 ENOG4107EF8 Glycosyl transferase (Group 1 BAX60_02635 ENOG4105QZI O-Antigen Polymerase BAX60_02640 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAX60_02645 ENOG4107RA4 Glycosyl transferase (Group 1 BAX60_02650 ENOG4105PSV Polysaccharide Biosynthesis Protein BAX60_02655 ENOG4105D3Q Sugar transferase BAX60_02665 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAX60_02670 ENOG4105JFG SpoIID LytB domain protein BAX60_02685 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAX60_02705 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAX60_02710 ENOG4105EY8 ABC transporter BAX60_02720 ENOG4107VDP teichoic acid biosynthesis BAX60_02725 ENOG41088M2 Glycosyl transferase family 2 BAX60_02775 ENOG4105DG6 mannose-6-phosphate isomerase BAX60_02795 ENOG4108NHD germination protein BAX60_02800 ENOG4105C54 Major Facilitator superfamily BAX60_02805 ENOG4108KGH TRANSCRIPTIONal BAX60_02810 ENOG4105J7I hydrolase BAX60_02815 ENOG4105K4H Nlp p60 protein BAX60_02825 ENOG4105PNM synthesis protein BAX60_02835 ENOG4105N98 Capsule biosynthesis protein capB BAX60_02840 ENOG4105ETE Transcriptional regulator (LacI family BAX60_02845 ENOG4108RVA ribokinase BAX60_02850 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BAX60_02855 ENOG4105C2J ABC transporter BAX60_02860 ENOG4105CNN ABC, transporter BAX60_02865 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAX60_02880 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BAX60_02885 ENOG4107FQX Alpha-acetolactate decarboxylase BAX60_02895 ENOG4107RSM transcriptional regulator BAX60_02910 ENOG4107XC4 flavin reductase domain protein, FMN-binding BAX60_02920 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BAX60_02930 ENOG4105CAH Chromate BAX60_02935 ENOG4105FGV Chromate BAX60_02945 ENOG4108WS4 fmn reductase BAX60_02950 ENOG4107V2S Transcriptional regulator BAX60_02960 ENOG410874W AraC family transcriptional regulator BAX60_02965 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BAX60_03000 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAX60_03005 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BAX60_03010 ENOG4107YJ4 chain length determinant protein BAX60_03015 ENOG4105HTX biosynthesis protein BAX60_03025 ENOG4105KBK Zinc finger, swim domain protein BAX60_03030 ENOG4105C0D helicase BAX60_03035 ENOG410667J hydrolase BAX60_03040 ENOG4105E98 transcriptional regulator DeoR family BAX60_03045 ENOG4105Z8H single-stranded DNA-binding protein BAX60_03070 ENOG4108VAC response regulator BAX60_03080 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) BAX60_03085 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BAX60_03095 ENOG4105CGA flagellar basal-body rod protein FlgG BAX60_03105 ENOG4105DFF Rod shape-determining protein mreb BAX60_03110 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BAX60_03120 ENOG4107MII Sugar-specific transcriptional regulator TrmB BAX60_03125 ENOG4105CZM Major Facilitator BAX60_03130 ENOG4108M26 parallel beta-helix repeat protein BAX60_03135 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BAX60_03140 ENOG41080V3 Major Facilitator superfamily BAX60_03145 ENOG4105D3W isochorismatase BAX60_03150 ENOG4107P26 BAX60_03155 ENOG4105BZU Histidine kinase BAX60_03165 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAX60_03175 ENOG4105FRN stage II sporulation protein BAX60_03180 ENOG4107TCE N-acetyltransferase BAX60_03200 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAX60_03205 ENOG4107TXC Transcriptional regulator BAX60_03210 ENOG4106BRK BAX60_03215 ENOG4108RYK Nad-dependent epimerase dehydratase BAX60_03220 ENOG4108Z40 Transcriptional regulator BAX60_03225 ENOG4105CQM Urea amidohydrolase subunit alpha BAX60_03230 ENOG4105KI2 Urea amidohydrolase subunit beta BAX60_03235 ENOG4108YZ9 Urea amidohydrolase subunit gamma BAX60_03240 ENOG4108IV0 ABC, transporter BAX60_03245 ENOG4105C0Z ABC transporter BAX60_03255 ENOG4105C32 Amino acid ABC transporter (Permease) BAX60_03260 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein BAX60_03285 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAX60_03295 ENOG4108TF4 von Willebrand factor, type A BAX60_03305 ENOG4105JFG SpoIID LytB domain protein BAX60_03310 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BAX60_03320 ENOG4106778 Protein of unknown function (DUF1146) BAX60_03335 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) BAX60_03340 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) BAX60_03345 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) BAX60_03350 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) BAX60_03375 ENOG4107RB6 it plays a direct role in the translocation of protons across the membrane (By similarity) BAX60_03385 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) BAX60_03390 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BAX60_03395 ENOG4108UIC UPF0340 protein BAX60_03400 ENOG4108YZG isomerase BAX60_03405 ENOG4107WAU Protein tyrosine phosphatase BAX60_03410 ENOG410815N Probably functions as a manganese efflux pump (By similarity) BAX60_03415 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAX60_03425 ENOG4108ZXQ stage ii sporulation protein r BAX60_03440 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BAX60_03445 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BAX60_03450 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BAX60_03460 ENOG4107TT2 Auxin Efflux Carrier BAX60_03465 ENOG4105C6K Malic enzyme BAX60_03470 ENOG4107104 thymidine kinase BAX60_03475 ENOG41082DI 50s ribosomal protein l31 BAX60_03480 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BAX60_03490 ENOG4105CBT Fructose-1,6-bisphosphatase BAX60_03495 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BAX60_03500 ENOG4107XMI Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway BAX60_03505 ENOG4105D2N Aldolase BAX60_03510 ENOG410812K response regulator receiver protein BAX60_03520 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BAX60_03530 ENOG4105C1G acyl-Coa dehydrogenase BAX60_03535 ENOG4105DF6 Fe-S oxidoreductase BAX60_03545 ENOG4105E5J UV damage endonuclease BAX60_03555 ENOG4105NAE bifunctional deaminase-reductase domain protein BAX60_03560 ENOG4105BZ1 (ABC) transporter BAX60_03565 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAX60_03580 ENOG4105R3A Nitrate reductase BAX60_03585 ENOG4108IUE nitrate reductase beta subunit BAX60_03605 ENOG4107V6Q Cyclic nucleotide-binding domain BAX60_03615 ENOG4105C75 arginyL-tRNA synthetase BAX60_03620 ENOG410684U Domain of unknown function (DUF1934) BAX60_03630 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E BAX60_03675 ENOG4107JM4 Tetratricopeptide repeat BAX60_03705 ENOG4108RDQ ABC transporter BAX60_03715 ENOG4105CYW agmatinase BAX60_03720 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BAX60_03725 ENOG4105BZ4 penicillin-binding protein BAX60_03735 ENOG4108XFG YwhD family BAX60_03740 ENOG4108Z4T Peptidase M50 BAX60_03745 ENOG41069HH 4-oxalocrotonate tautomerase BAX60_03750 ENOG41067TZ transcriptional regulator, MarR family BAX60_03755 ENOG4105C22 threonyL-tRNA synthetase BAX60_03770 ENOG4105DCI Phosphohydrolase BAX60_03780 ENOG4108VCI transcription factor, rsfa family BAX60_03785 ENOG4108RNG Permease of the drug metabolite transporter BAX60_03790 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BAX60_03795 ENOG4105DUM transcriptional regulator, lysR family BAX60_03800 ENOG4108IJ2 phosphate acetyltransferase BAX60_03815 ENOG4105CHM Aminotransferase BAX60_03825 ENOG4108V3M Inherit from COG: acetyl-CoA carboxylase biotin carboxylase BAX60_03830 ENOG4105CHR reductase BAX60_03835 ENOG4106CHD Bacilysin biosynthesis protein bacB BAX60_03840 ENOG41061WN bacilysin biosynthesis protein BAX60_03845 ENOG4105FCW Major Facilitator superfamily BAX60_03860 ENOG4105C26 Dehydrogenase BAX60_03865 ENOG4105D82 Glutamate dehydrogenase BAX60_03875 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase BAX60_03880 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BAX60_03885 ENOG4105C1B dTDP-glucose 4-6-dehydratase BAX60_03890 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BAX60_03895 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG BAX60_03900 ENOG4107TY6 Acylneuraminate cytidylyltransferase BAX60_03910 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD BAX60_03915 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BAX60_03955 ENOG4105C26 Dehydrogenase BAX60_03960 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) BAX60_03965 ENOG4108RJ9 Glycosyl transferase, family 2 BAX60_03985 ENOG4105DWF phosphomethylpyrimidine kinase BAX60_04000 ENOG4105C5Y PTS System BAX60_04005 ENOG4108QTI )-transporter BAX60_04020 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BAX60_04025 ENOG4105DEN Luciferase family BAX60_04030 ENOG4108DBC nitroreductase BAX60_04070 ENOG4107BMA Transglycosylase associated protein BAX60_04080 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BAX60_04085 ENOG4105WH5 Teichoic acid glycosylation protein BAX60_04110 ENOG4107ZXU DSBA oxidoreductase BAX60_04115 ENOG4105DBE peroxidase BAX60_04120 ENOG410650H (LipO)protein BAX60_04125 ENOG4107SJW iron permease, FTR1 BAX60_04135 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BAX60_04145 ENOG4105CMU LysR family (Transcriptional regulator BAX60_04150 ENOG4105VAW lrga family BAX60_04155 ENOG41067MG lrgb family BAX60_04160 ENOG4105D8G Major Facilitator superfamily BAX60_04170 ENOG4105DR4 Methyltransferase BAX60_04180 ENOG4108YV3 Protein of unknown function (DUF2711) BAX60_04185 ENOG4105CK1 PTS System BAX60_04195 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin BAX60_04210 ENOG4105X1N Glycosyl transferase family 8 BAX60_04220 ENOG4105GVJ transcriptional regulator BAX60_04225 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAX60_04230 ENOG4105IIU Aminopeptidase BAX60_04240 ENOG4105DQ6 Transposase BAX60_04250 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAX60_04260 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) BAX60_04265 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAX60_04275 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAX60_04280 ENOG4108VHC Short-chain dehydrogenase reductase Sdr BAX60_04285 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAX60_04290 ENOG4105F8D glycoside hydrolase family 4 BAX60_04295 ENOG4105VCP PTS System BAX60_04300 ENOG4105CK1 PTS System BAX60_04305 ENOG4105VZJ PTS System BAX60_04310 ENOG4105EMD TRANSCRIPTIONal BAX60_04320 ENOG4108VX5 3-methyladenine DNA glycosylase BAX60_04325 ENOG4105CH6 catalase BAX60_04340 ENOG4105DA5 (ABC) transporter BAX60_04345 ENOG41069JR BAX60_04365 ENOG4105ETS cytosine purines uracil thiamine allantoin BAX60_04370 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BAX60_04375 ENOG4108JJ8 (ABC) transporter BAX60_04380 ENOG4108JJ9 ABC, transporter BAX60_04385 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAX60_04390 ENOG4105C4M (Ubiquinol oxidase) subunit I BAX60_04395 ENOG4105D2K citrate carrier protein BAX60_04410 ENOG4107BJW polysaccharide deacetylase BAX60_04440 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAX60_04450 ENOG4105CMR udp-glucose 4-epimerase BAX60_04460 ENOG4105BZU Histidine kinase BAX60_04465 ENOG4105WH1 Two component transcriptional regulator luxr family BAX60_04470 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BAX60_04500 ENOG4105DTD Dehydrogenase BAX60_04505 ENOG4108IIH CoA-transferase subunit B BAX60_04510 ENOG4105D6N CoA-transferase, subunit a BAX60_04515 ENOG4105CY2 Citrate transporter BAX60_04525 ENOG4105DHI Methyltransferase BAX60_04550 ENOG4105CH6 catalase BAX60_04555 ENOG4105D4T Citrate transporter BAX60_04560 ENOG410900G Protein of unknown function (DUF421) BAX60_04570 ENOG4105CS2 ec 3.2.1.21 BAX60_04575 ENOG4105C5Y PTS System BAX60_04580 ENOG4105CID antiterminator BAX60_04590 ENOG4105DEU major facilitator superfamily BAX60_04595 ENOG4105C1J atp-dependent rna helicase BAX60_04600 ENOG4107TDE lipolytic protein G-D-S-L family BAX60_04675 ENOG4107YZX Universal stress protein BAX60_04680 ENOG4105CS2 ec 3.2.1.21 BAX60_04685 ENOG4105C5Y PTS System BAX60_04715 ENOG4106Z5D Glycoside Hydrolase Family 43 BAX60_04730 ENOG4105C84 Histidine ammonia-lyase BAX60_04735 ENOG4105CGP Urocanate hydratase BAX60_04740 ENOG4105CI2 imidazolone-5-propionate hydrolase BAX60_04745 ENOG4107W25 arginase agmatinase formiminoglutamase BAX60_04755 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BAX60_04760 ENOG4105D9N nucleoside BAX60_04770 ENOG4107RHR regulatoR BAX60_04775 ENOG4108TM9 integral membrane protein BAX60_04780 ENOG4105ENY Ethanolamine utilization protein eutH BAX60_04785 ENOG4108PGP mmge prpd family protein BAX60_04790 ENOG4105CH2 amidohydrolase BAX60_04800 ENOG4108HW4 amino acid AbC transporter BAX60_04805 ENOG4105EAB amino acid AbC transporter BAX60_04810 ENOG4108XSB acetyltransferase, (GNAT) family BAX60_04815 ENOG4105CPU Monooxygenase BAX60_04820 ENOG4107QHE Choloylglycine hydrolase BAX60_04825 ENOG410667J hydrolase BAX60_04855 ENOG4108V5C ABC transporter BAX60_04885 ENOG4105D2N Aldolase BAX60_04890 ENOG4105WZ4 isomerase BAX60_04895 ENOG4105F0H myo-inositol catabolism protein BAX60_04900 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BAX60_04910 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BAX60_04915 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BAX60_04920 ENOG4105D7K pfkb domain protein BAX60_04930 ENOG4105C26 Dehydrogenase BAX60_04940 ENOG4105CPC Aldo Keto reductase BAX60_04955 ENOG4107QNK )-transporter BAX60_04960 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BAX60_04970 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BAX60_04980 ENOG4105ST3 Transcriptional regulator BAX60_04985 ENOG4105C26 Dehydrogenase BAX60_05000 ENOG41085PJ rdd domain containing protein BAX60_05015 ENOG4105J7D transcriptional regulator BAX60_05020 ENOG4107JEE Short-chain dehydrogenase reductase Sdr BAX60_05025 ENOG41061AU MarR family Transcriptional regulator BAX60_05035 ENOG41067MG lrgb family BAX60_05050 ENOG4105BZW Glycerate kinase BAX60_05055 ENOG4105G3Z GntR family transcriptional regulator BAX60_05060 ENOG4105CMG Carbohydrate kinase BAX60_05065 ENOG4105C6Z Gluconate BAX60_05070 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BAX60_05075 ENOG4105D3R alkyl hydroperoxide reductase BAX60_05080 ENOG4108JU3 Alkyl hydroperoxide reductase BAX60_05085 ENOG4107R3N Filamentation induced by cAMP protein fic BAX60_05095 ENOG4105CS2 ec 3.2.1.21 BAX60_05105 ENOG4108S3Y transcriptional regulator BAX60_05115 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 BAX60_05120 ENOG4107RRE RNA-directed DNA polymerase BAX60_05125 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BAX60_05130 ENOG4105D9P serine threonine protein kinase BAX60_05135 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BAX60_05150 ENOG4105E2A Dehydrogenase BAX60_05170 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BAX60_05175 ENOG4105WQG acetyltransferase BAX60_05180 ENOG410780I phosphoprotein phosphatase activity BAX60_05190 ENOG41066UZ arginase EC 3.5.3.1 BAX60_05195 ENOG4108IQI permease BAX60_05200 ENOG4105C8Y Acetylornithine aminotransferase BAX60_05205 ENOG4108JUB Transcriptional regulator BAX60_05220 ENOG4105C0H protease BAX60_05225 ENOG4105Q2H domain protein BAX60_05240 ENOG4105BZU Histidine kinase BAX60_05245 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAX60_05270 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BAX60_05275 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BAX60_05280 ENOG4105CDU Replicative dna helicase BAX60_05305 ENOG4105DJ2 Major Facilitator Superfamily BAX60_05310 ENOG4105EDW glycosyl transferase, family 39 BAX60_05315 ENOG4105K9Q Binds to the 23S rRNA (By similarity) BAX60_05320 ENOG4105BZR domain protein BAX60_05325 ENOG4108XMW Membrane BAX60_05340 ENOG4105KVH Transcriptional regulator BAX60_05345 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase BAX60_05370 ENOG4108VSZ Inherit from COG: ketosteroid isomerase-like protein BAX60_05375 ENOG4105DDN Pentapeptide repeat-containing protein BAX60_05380 ENOG4105D94 Major Facilitator Superfamily BAX60_05385 ENOG4107RSM transcriptional regulator BAX60_05390 ENOG41082BV acetyltransferase BAX60_05395 ENOG41081I9 integral membrane protein BAX60_05410 ENOG4105KVH Transcriptional regulator BAX60_05415 ENOG4108U05 Transcriptional regulator BAX60_05420 ENOG41082BV acetyltransferase BAX60_05440 ENOG4105WAB arsR family transcriptional regulator BAX60_05480 ENOG41067SE Tetr family transcriptional regulator BAX60_05495 ENOG4105C7Z Conserved Protein BAX60_05500 ENOG4107FCW Abortive infection protein BAX60_05510 ENOG4108UW5 maltose o-acetyltransferase BAX60_05515 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BAX60_05525 ENOG4105CGK Exodeoxyribonuclease III BAX60_05530 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BAX60_05535 ENOG4108UUM single-stranded DNA-binding protein BAX60_05540 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BAX60_05545 ENOG4105C3G gtp-binding protein BAX60_05550 ENOG4108J2R molybdopterin oxidoreductase BAX60_05555 ENOG4105VDK protein, conserved in bacteria BAX60_05565 ENOG4108ZDA Sporulation protein YyaC BAX60_05570 ENOG4105FA0 parb-like partition protein BAX60_05575 ENOG4107QJE Chromosome Partitioning Protein BAX60_05590 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) BAX60_05595 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BAX60_05600 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BAX60_05615 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) BAX60_05625 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) BAX60_05630 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAX60_05635 ENOG410848D S4 domain protein YaaA BAX60_05650 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAX60_05655 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAX60_05690 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BAX60_05700 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) BAX60_05705 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) BAX60_05710 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BAX60_05720 ENOG4105ZMH deoxynucleoside kinase BAX60_05730 ENOG4105VRS hydrolase family 18 BAX60_05735 ENOG4105GTG Isochorismatase BAX60_05740 ENOG4108Z6B deaminase BAX60_05750 ENOG4105C6E dna polymerase iii BAX60_05755 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) BAX60_05760 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BAX60_05770 ENOG41067KS pro-sigma K processing BAX60_05810 ENOG4105CDW Resistance protein BAX60_05815 ENOG4105CXN decarboxylase BAX60_05820 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) BAX60_05825 ENOG4105X0R protein from nitrogen regulatory protein P-II BAX60_05830 ENOG4105XVJ Protein of unknown function (DUF327) BAX60_05835 ENOG4105FA2 dna polymerase iii BAX60_05840 ENOG4105MA4 psp1 domain protein BAX60_05845 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) BAX60_05850 ENOG41060K3 Methyltransferase BAX60_05855 ENOG4105VC4 domain protein BAX60_05860 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BAX60_05865 ENOG4105KRN Transcriptional regulator, abrb family BAX60_05870 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BAX60_05875 ENOG4105F8V Hydrolase, tatD family BAX60_05880 ENOG41069ER domain protein BAX60_05890 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BAX60_05895 ENOG4105XFA sporulation peptidase YabG BAX60_05900 ENOG4105W42 Veg protein BAX60_05905 ENOG4105XEW small acid-soluble spore protein BAX60_05910 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) BAX60_05915 ENOG4105DFT pur operon repressor BAX60_05920 ENOG4105KME endoribonuclease L-psp BAX60_05925 ENOG4105K4W Could be involved in septation (By similarity) BAX60_05935 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BAX60_05940 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BAX60_05945 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) BAX60_05950 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BAX60_05960 ENOG4108JA2 transcriptioN-repair coupling factor BAX60_05965 ENOG4108M14 stage v sporulation protein t BAX60_05975 ENOG4108IY2 MazG family BAX60_05980 ENOG41082I2 s4 domain protein BAX60_05985 ENOG4105VYY sporulation protein yabp BAX60_06000 ENOG41060GV RNA binding s1 domain protein BAX60_06030 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BAX60_06035 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAX60_06040 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BAX60_06050 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BAX60_06055 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase BAX60_06060 ENOG4105C6T cysteine synthase BAX60_06065 ENOG4105CRQ synthase (Component I) BAX60_06070 ENOG4105DDQ anthranilate synthase BAX60_06075 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BAX60_06080 ENOG4105EEI dihydropteroate synthase BAX60_06085 ENOG4105KRF dihydroneopterin aldolase BAX60_06090 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BAX60_06100 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BAX60_06105 ENOG4105CRK lysyL-tRNA synthetase BAX60_06195 ENOG4108Z0C Uvrb UvrC protein BAX60_06200 ENOG41066A3 ATP guanido phosphotransferase BAX60_06210 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BAX60_06215 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) BAX60_06220 ENOG4105CTP PilT protein domain protein BAX60_06225 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BAX60_06230 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) BAX60_06235 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) BAX60_06245 ENOG4105D7W serine acetyltransferase BAX60_06250 ENOG4105C8N cysteinyl-tRNA synthetase BAX60_06255 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) BAX60_06260 ENOG4105C2N RNA methyltransferase TrmH family group 3 BAX60_06265 ENOG4105M0M Tetracycline resistance protein BAX60_06285 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BAX60_06290 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) BAX60_06300 ENOG4108VZM 50s ribosomal protein L10 BAX60_06305 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) BAX60_06310 ENOG4107Y49 methyltransferase BAX60_06315 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAX60_06320 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAX60_06325 ENOG4105XPM ribosomal protein BAX60_06330 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) BAX60_06335 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BAX60_06340 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BAX60_06345 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BAX60_06350 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAX60_06355 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) BAX60_06360 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) BAX60_06365 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BAX60_06370 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BAX60_06375 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BAX60_06380 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BAX60_06385 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) BAX60_06390 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BAX60_06395 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BAX60_06400 ENOG41082SA 50s ribosomal protein l29 BAX60_06405 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BAX60_06410 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) BAX60_06420 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits BAX60_06430 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BAX60_06435 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BAX60_06440 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) BAX60_06445 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BAX60_06450 ENOG4105VPB 50S ribosomal protein L30 BAX60_06455 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) BAX60_06460 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAX60_06470 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAX60_06480 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BAX60_06490 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BAX60_06495 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) BAX60_06500 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAX60_06505 ENOG4108ZT0 50S ribosomal protein l17 BAX60_06510 ENOG4108JJB ABC transporter BAX60_06515 ENOG4108JJB ABC transporter BAX60_06520 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAX60_06525 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAX60_06530 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) BAX60_06535 ENOG4108UJD 30S ribosomal protein S9 BAX60_06545 ENOG4108I0C methyltransferase BAX60_06560 ENOG4105D1F ATP-binding protein BAX60_06575 ENOG4108NMV polysaccharide deacetylase BAX60_06660 ENOG4108JPW Aminotransferase BAX60_06670 ENOG4105CPQ Dehydrogenase BAX60_06675 ENOG4105CHH sulfate transporter BAX60_06685 ENOG4108SA1 esterase BAX60_06705 ENOG410874W AraC family transcriptional regulator BAX60_06710 ENOG4105EHZ conserved protein UCP016719 BAX60_06715 ENOG4105D17 glycoside hydrolase, family 3 domain protein BAX60_06735 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BAX60_06745 ENOG4105EWC Purine nucleoside phosphorylase BAX60_06775 ENOG4105EMN RNA polymerase sigma factor BAX60_06785 ENOG4105C8B TIGR00159 family BAX60_06790 ENOG4107U5W ybbr family BAX60_06795 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) BAX60_06810 ENOG4108TWJ NADH dehydrogenase subunit 5 BAX60_06830 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BAX60_06835 ENOG4105WAB arsR family transcriptional regulator BAX60_06840 ENOG4108RWP Major Facilitator Superfamily protein BAX60_06875 ENOG4105G0J serine threonine protein kinase BAX60_06885 ENOG4106K80 BAX60_06895 ENOG4106DDH Sporulation-specific SASP protein BAX60_06905 ENOG4108HWY Beta-lactamase BAX60_06910 ENOG4107E6A Cytochrome p-450 BAX60_06925 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAX60_06930 ENOG4105CXY transporter BAX60_06945 ENOG410645S MarR family Transcriptional regulator BAX60_06950 ENOG4105DCM major facilitator superfamily BAX60_06965 ENOG410631K Membrane BAX60_06970 ENOG4106AXJ AraC family transcriptional regulator BAX60_06975 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BAX60_06980 ENOG4108TCS Glutamyl endopeptidase BAX60_06990 ENOG4108WC5 Alpha Beta Hydrolase Fold protein BAX60_06995 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAX60_07000 ENOG4107ZTW SNARE associated Golgi BAX60_07020 ENOG4105C72 UPF0176 protein BAX60_07030 ENOG4108IIZ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane BAX60_07035 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BAX60_07040 ENOG4108X79 transcriptional regulator BAX60_07050 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAX60_07055 ENOG4108IQI permease BAX60_07060 ENOG4108J5H Homocysteine s-methyltransferase BAX60_07075 ENOG4105CSV Glutaminase BAX60_07090 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase BAX60_07095 ENOG4105C26 Dehydrogenase BAX60_07100 ENOG4105DJB Major Facilitator Superfamily BAX60_07105 ENOG4105EQX glucarate dehydratase BAX60_07110 ENOG41073TP transcriptional regulator BAX60_07115 ENOG4105CTX dehydratase BAX60_07130 ENOG4106UX7 integral membrane protein BAX60_07135 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAX60_07170 ENOG4105MUA Resistance protein BAX60_07180 ENOG4105DGI Alkaline phosphatase BAX60_07185 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BAX60_07190 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAX60_07195 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) BAX60_07200 ENOG4107EPV Aminotransferase class V BAX60_07205 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAX60_07210 ENOG4105J7D transcriptional regulator BAX60_07215 ENOG4107RB3 L-asparaginase BAX60_07220 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold BAX60_07230 ENOG41060AI SEC-C motif BAX60_07240 ENOG4107Y7X LytTR BAX60_07245 ENOG4108IUW ABC transporter BAX60_07250 ENOG4108SDH ABC, transporter BAX60_07255 ENOG4107SET aldo keto reductase BAX60_07285 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BAX60_07295 ENOG4105DSE periplasmic solute binding protein BAX60_07300 ENOG4105DIK (ABC) transporter BAX60_07310 ENOG4105DEN Luciferase family BAX60_07315 ENOG4108N0M stress protein BAX60_07320 ENOG4106FN3 tellurium resistance protein BAX60_07325 ENOG4106FN3 tellurium resistance protein BAX60_07330 ENOG4107TS3 membrane protein, TerC BAX60_07335 ENOG4108TTB tellurium resistance protein BAX60_07345 ENOG41079KZ Major Facilitator Superfamily BAX60_07350 ENOG4107XZQ multidrug resistance protein BAX60_07355 ENOG4108A65 Transcriptional regulator BAX60_07360 ENOG4108IJ7 Glycine betaine BAX60_07365 ENOG4107SQ8 Glycine betaine BAX60_07400 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAX60_07435 ENOG4105EIG urea carboxylase-associated protein 1 BAX60_07440 ENOG4107RA1 nh(3)-dependent nad( ) synthetase BAX60_07450 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BAX60_07455 ENOG41089UC methyltransferase, type 11 BAX60_07460 ENOG4105C5Q Transcriptional regulator BAX60_07465 ENOG4105I82 acetyl xylan esterase BAX60_07470 ENOG410756H nucleotidyltransferase BAX60_07480 ENOG4105C26 Dehydrogenase BAX60_07485 ENOG4105CK7 Sodium proline symporter BAX60_07490 ENOG4107YHD transcriptional regulator BAX60_07500 ENOG4108PJD permease BAX60_07505 ENOG4105U6C Alpha beta hydrolase fold protein BAX60_07515 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAX60_07520 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BAX60_07525 ENOG4108IFG nitrite reductase, (NAD(P)H) BAX60_07530 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BAX60_07550 ENOG4105S7A ErfK ybiS ycfS ynhG family protein BAX60_07560 ENOG4105CKI cobalamin synthesis protein BAX60_07565 ENOG4105E5Q amino acid AbC transporter BAX60_07570 ENOG4107XKZ Amino acid ABC superfamily ATP binding cassette transporter binding protein BAX60_07590 ENOG4105K56 Transcriptional regulator BAX60_07600 ENOG4108VEN abc transporter atp-binding protein BAX60_07620 ENOG4105C8Q Methyl-accepting chemotaxis BAX60_07625 ENOG41080HJ 6-phospho 3-hexuloisomerase BAX60_07630 ENOG4108VA3 3-hexulose-6-phosphate synthase BAX60_07635 ENOG4105KVH Transcriptional regulator BAX60_07645 ENOG4105CEY Amp-dependent synthetase and ligase BAX60_07675 ENOG4105SX7 Transporter BAX60_07685 ENOG4105W8Z 4'-phosphopantetheinyl transferase BAX60_07700 ENOG4105CDA abc transporter atp-binding protein BAX60_07705 ENOG4105DRP amino acid AbC transporter BAX60_07715 ENOG4106P55 Transcriptional regulator BAX60_07720 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BAX60_07725 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) BAX60_07730 ENOG41069ZX BAX60_07735 ENOG41069ZX BAX60_07745 ENOG4105DUX Transporter BAX60_07760 ENOG4105E1K spore germination protein BAX60_07780 ENOG4107WD8 ABC transporter, permease BAX60_07785 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAX60_07790 ENOG4105BZU Histidine kinase BAX60_07810 ENOG4105CFH Aspartokinase BAX60_07815 ENOG4105DHS permease protein BAX60_07820 ENOG4105CM4 permease protein BAX60_07825 ENOG4108IPW abc transporter atp-binding protein BAX60_07840 ENOG4105R8C Transcriptional regulator BAX60_07845 ENOG4108DBC nitroreductase BAX60_07850 ENOG41067V3 Antibiotic biosynthesis monooxygenase BAX60_07855 ENOG4105YVS arsR family transcriptional regulator BAX60_07865 ENOG4108JPW Aminotransferase BAX60_07870 ENOG4105C26 Dehydrogenase BAX60_07880 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BAX60_07885 ENOG4105KTB nuclear export factor GLE1 BAX60_07890 ENOG4108T5E Copper resistance protein BAX60_07895 ENOG4108ZYE Transcriptional regulator BAX60_07920 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAX60_07945 ENOG4105E7W lamb ycsf family protein BAX60_07950 ENOG4105C5A transporter BAX60_07955 ENOG4105CFM UPF0317 protein BAX60_07960 ENOG4105P4J Allophanate hydrolase, subunit 1 BAX60_07970 ENOG4107258 Transcriptional regulator BAX60_07975 ENOG4105XJB lipolytic protein G-D-S-L family BAX60_07985 ENOG41061CK Antibiotic biosynthesis monooxygenase BAX60_07990 ENOG4107RVG penicillin-binding protein BAX60_07995 ENOG4107QM2 Aldo Keto reductase BAX60_08000 ENOG4105ETD TRANSCRIPTIONal BAX60_08010 ENOG4105HMZ Methyltransferase BAX60_08015 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BAX60_08030 ENOG410606W general stress protein BAX60_08040 ENOG4105VCH membrane BAX60_08050 ENOG4105C9U ATP-dependent DNA helicase RecQ BAX60_08065 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BAX60_08070 ENOG4107R8N Glycosyl transferase, family 2 BAX60_08080 ENOG4105C0X amino acid BAX60_08105 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BAX60_08115 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) BAX60_08120 ENOG4105EU9 BAX60_08125 ENOG4105QVS general stress protein BAX60_08130 ENOG41082W1 Cupin 2, conserved barrel domain protein BAX60_08145 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BAX60_08150 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BAX60_08155 ENOG4108MRH transcriptional regulatory protein BAX60_08160 ENOG4107QJT sodium dicarboxylate symporter BAX60_08165 ENOG4106F5Q Membrane BAX60_08175 ENOG4105CJ1 ABC, transporter BAX60_08190 ENOG4105FDT acyl-CoA dehydrogenase BAX60_08210 ENOG4105SZ6 Thioredoxin BAX60_08215 ENOG4105CPF Cell wall formation (By similarity) BAX60_08220 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAX60_08230 ENOG4105C1J atp-dependent rna helicase BAX60_08235 ENOG410905X membrane-flanked domain protein BAX60_08240 ENOG4105CKV Membrane BAX60_08250 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) BAX60_08255 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BAX60_08260 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAX60_08270 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BAX60_08275 ENOG4107MMM Anti-sigma-factor antagonist BAX60_08280 ENOG4105FUA antagonist BAX60_08285 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase BAX60_08290 ENOG4107SGM protein serine threonine phosphatase BAX60_08295 ENOG4105WN5 stage II sporulation protein BAX60_08300 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BAX60_08310 ENOG41064BQ Phosphatase BAX60_08365 ENOG4105VZ8 Transcriptional regulator BAX60_08375 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAX60_08380 ENOG4105DJ2 Major Facilitator Superfamily BAX60_08385 ENOG4107RSM transcriptional regulator BAX60_08390 ENOG4108RPX mosc domain containing protein BAX60_08395 ENOG4105N14 lysine exporter protein LysE YggA BAX60_08405 ENOG4105ECK Fatty Acid Desaturase BAX60_08415 ENOG4105VEQ Cold shock protein BAX60_08420 ENOG4108VJ1 Transcriptional regulator (CarD family BAX60_08430 ENOG4105DJ2 Major Facilitator Superfamily BAX60_08435 ENOG4108IMY Transcriptional regulator BAX60_08440 ENOG41086D8 Transcriptional regulator BAX60_08450 ENOG4105CZ9 Domain of unknown function (DU1801) BAX60_08465 ENOG4105GIG BAX60_08470 ENOG4105DTD Dehydrogenase BAX60_08475 ENOG4105KRI phosphocarrier protein (HPr BAX60_08480 ENOG4105ST3 Transcriptional regulator BAX60_08490 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein BAX60_08500 ENOG4105T38 integral membrane protein BAX60_08505 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAX60_08510 ENOG4108ZMQ domain protein BAX60_08515 ENOG4105MJ9 esterase BAX60_08520 ENOG4107Z6X Transcriptional regulator BAX60_08530 ENOG4105KVH Transcriptional regulator BAX60_08535 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BAX60_08540 ENOG41082YX Transcriptional regulator, arsr family BAX60_08545 ENOG4107R5R arsenical pump membrane protein BAX60_08550 ENOG4108UXE Protein tyrosine phosphatase BAX60_08555 ENOG4105Z7P Acetyltransferase (GNAT) family BAX60_08560 ENOG4108KGH TRANSCRIPTIONal BAX60_08565 ENOG4108ZJ4 polysaccharide deacetylase BAX60_08575 ENOG4105BZU Histidine kinase BAX60_08580 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAX60_08585 ENOG4107Y9U Membrane BAX60_08595 ENOG4108SQ9 flavin reductase domain protein, FMN-binding BAX60_08600 ENOG4108ZHR arsR family transcriptional regulator BAX60_08605 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BAX60_08615 ENOG4105ENE Histidine kinase BAX60_08620 ENOG4108VB1 regulatoR BAX60_08625 ENOG4105EYF MMPL domain protein BAX60_08630 ENOG4107U9B transcriptional regulator BAX60_08635 ENOG4108UMN azlc family BAX60_08640 ENOG4105KMT branched-chain amino acid BAX60_08655 ENOG4108UQV Membrane BAX60_08660 ENOG4108Z5V transcriptional regulator, merr family BAX60_08665 ENOG41076HS cation diffusion facilitator family transporter BAX60_08670 ENOG4108TVJ Nitroreductase BAX60_08675 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BAX60_08680 ENOG4108VGI doxx family BAX60_08685 ENOG4105XXY Thioredoxin BAX60_08695 ENOG4108VQJ O-methyltransferase BAX60_08735 ENOG4105WQG acetyltransferase BAX60_08745 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BAX60_08750 ENOG4105ETE Transcriptional regulator (LacI family BAX60_08755 ENOG4105C54 Major Facilitator superfamily BAX60_08760 ENOG4107TRE AP endonuclease, family 2 BAX60_08765 ENOG4105F27 Major Facilitator BAX60_08780 ENOG4105C85 amino acid BAX60_08790 ENOG41062A4 Transcriptional regulator BAX60_08795 ENOG4105EYF MMPL domain protein BAX60_08800 ENOG4108TVJ Nitroreductase BAX60_08805 ENOG4105FS7 Transcriptional regulator BAX60_08810 ENOG4108JCI Transcriptional regulator BAX60_08825 ENOG4105C2C drug resistance transporter, Bcr CflA BAX60_08835 ENOG4105DRR Transcriptional regulator, GntR family BAX60_08840 ENOG4105VRS hydrolase family 18 BAX60_08855 ENOG4105G6Z alkaline phosphatase BAX60_08875 ENOG4107TVP HD domain protein BAX60_08880 ENOG41090UD (LipO)protein BAX60_08885 ENOG4105F27 Major Facilitator BAX60_08890 ENOG4105VZJ PTS System BAX60_08895 ENOG4105VCP PTS System BAX60_08900 ENOG4105CK1 PTS System BAX60_08905 ENOG4105CS2 ec 3.2.1.21 BAX60_08910 ENOG4108TZY GntR Family Transcriptional Regulator BAX60_08915 ENOG4105EVU fructokinase BAX60_08920 ENOG4105DG6 mannose-6-phosphate isomerase BAX60_08925 ENOG4105D3P Mannan endo-1,4-beta-mannosidase BAX60_08970 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BAX60_08975 ENOG4105K8N protein family UPF0079, ATPase BAX60_08980 ENOG41072GX Peptidase M22 Glycoprotease BAX60_08985 ENOG410801F ribosomal-protein-alanine acetyltransferase BAX60_08990 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAX60_08995 ENOG4105C5H ABC transporter BAX60_09000 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAX60_09005 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) BAX60_09010 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BAX60_09015 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAX60_09025 ENOG4108TYN CAAX amino terminal protease family protein BAX60_09030 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BAX60_09035 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BAX60_09040 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAX60_09075 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAX60_09080 ENOG4105PGZ NB-ARC domain BAX60_09085 ENOG4105CPQ Dehydrogenase BAX60_09090 ENOG4105CT4 transporter BAX60_09100 ENOG41087YS Phage shock protein A BAX60_09105 ENOG4105DQX Zinc finger domain BAX60_09110 ENOG4108WV1 Pfam:DUF477 BAX60_09120 ENOG4108ZMR Ion transport 2 domain-containing protein BAX60_09125 ENOG4107QNK )-transporter BAX60_09155 ENOG4107YUH hydrolase BAX60_09165 ENOG4107STQ Multicopper oxidase BAX60_09170 ENOG4105C85 amino acid BAX60_09185 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAX60_09205 ENOG4105C7N Xanthine uracil vitamin C permease BAX60_09230 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BAX60_09235 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BAX60_09240 ENOG4105C83 adenylosuccinate lyase BAX60_09245 ENOG4105C8V SAICAR synthetase BAX60_09250 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BAX60_09255 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I BAX60_09260 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii BAX60_09270 ENOG4105CXB phosphoribosylaminoimidazole synthetase BAX60_09275 ENOG4108V3E phosphoribosylglycinamide formyltransferase BAX60_09280 ENOG4105DC1 bifunctional purine biosynthesis protein purh BAX60_09285 ENOG4105C12 Phosphoribosylglycinamide synthetase BAX60_09295 ENOG4105DVH amino acid BAX60_09310 ENOG4108R5T secreted protein BAX60_09315 ENOG4105KGF protein, YerC YecD BAX60_09320 ENOG4105CBC glutamate synthase BAX60_09325 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) BAX60_09330 ENOG4105C4R Atp-dependent dna helicase BAX60_09335 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BAX60_09345 ENOG4105CRN Aminoglycoside phosphotransferase BAX60_09350 ENOG4105KT7 mgtC SapB transporter BAX60_09355 ENOG4105CK7 Sodium proline symporter BAX60_09360 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BAX60_09365 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAX60_09370 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BAX60_09375 ENOG4108IG5 Transcriptional regulator BAX60_09385 ENOG4105CBD Diacylglycerol kinase BAX60_09390 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAX60_09420 ENOG4105CNU cell division protein FtsK BAX60_09465 ENOG4105CDY transcriptional regulatory protein BAX60_09475 ENOG4105M4P Tetr family transcriptional regulator BAX60_09480 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein BAX60_09485 ENOG4107S9F NmrA family BAX60_09500 ENOG4105WEF catalase BAX60_09505 ENOG4105M18 -acetyltransferase BAX60_09515 ENOG4105C2F Histidine kinase BAX60_09520 ENOG4105EQD regulatoR BAX60_09525 ENOG410769Z extracellular solute-binding protein family 1 BAX60_09530 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BAX60_09535 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BAX60_09540 ENOG4105F5H Glycosyl Hydrolase Family 88 BAX60_09545 ENOG41075H3 AraC family transcriptional regulator BAX60_09550 ENOG4107TDE lipolytic protein G-D-S-L family BAX60_09565 ENOG4105CX8 fg-gap repeat protein BAX60_09570 ENOG4105CX8 fg-gap repeat protein BAX60_09575 ENOG4107TDE lipolytic protein G-D-S-L family BAX60_09585 ENOG4105EKC BAX60_09590 ENOG4105E0S extracellular solute-binding protein family 1 BAX60_09600 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component BAX60_09605 ENOG4105F8D glycoside hydrolase family 4 BAX60_09610 ENOG4105H67 Protein of unknown function (DUF421) BAX60_09615 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BAX60_09620 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BAX60_09640 ENOG4106I4J membrane BAX60_09650 ENOG41082F9 transcriptional regulator BAX60_09655 ENOG41061H0 Monooxygenase BAX60_09660 ENOG4108R1P BAX60_09665 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAX60_09670 ENOG4105E0M Sulfatase BAX60_09675 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BAX60_09685 ENOG41090R9 glycosyltransferase BAX60_09690 ENOG4107R51 Glycosyl transferase, family 2 BAX60_09695 ENOG41090R9 glycosyltransferase BAX60_09700 ENOG4105EU0 Major facilitator Superfamily BAX60_09710 ENOG4105CUB amino acid BAX60_09715 ENOG4105C26 Dehydrogenase BAX60_09720 ENOG4105FKZ Methyl-accepting chemotaxis BAX60_09725 ENOG4105C5H ABC transporter BAX60_09735 ENOG4107SWG transcriptional regulator MERR family BAX60_09740 ENOG4105DXB Major Facilitator superfamily BAX60_09755 ENOG4105C5H ABC transporter BAX60_09760 ENOG4105FDU atp-dependent rna helicase BAX60_09770 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BAX60_09775 ENOG4105E0A ABC, transporter BAX60_09780 ENOG4108U1V ABC transporter, permease BAX60_09785 ENOG4105DQ5 transport system permease protein BAX60_09790 ENOG4108HUF Transporter BAX60_09805 ENOG4108J20 pectate lyase BAX60_09810 ENOG4107QPK )-transporter BAX60_09820 ENOG4108MRH transcriptional regulatory protein BAX60_09850 ENOG410855V Acylphosphatase BAX60_09855 ENOG4108RPX mosc domain containing protein BAX60_09875 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BAX60_09910 ENOG4105E1K spore germination protein BAX60_09915 ENOG4105C5Y PTS System BAX60_09920 ENOG4105CG3 alpha amylase, catalytic region BAX60_09925 ENOG4107414 GntR family transcriptional regulator BAX60_09930 ENOG4108RCM Nitroreductase BAX60_09935 ENOG4105CGH 5'-nucleotidase BAX60_09940 ENOG4107RKG DJ-1/PfpI family BAX60_09955 ENOG4105KJF protein tyrosine phosphatase BAX60_09965 ENOG4107U9T Pfam:Ribonuclease_BN BAX60_09975 ENOG4108ISG Major Facilitator BAX60_09985 ENOG4105UPD Calcium Proton BAX60_09995 ENOG4105D8X mechanosensitive ion channel BAX60_10015 ENOG4106KE4 Dehydrogenase BAX60_10020 ENOG4105D7N magnesium and cobalt transport protein CorA BAX60_10030 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAX60_10040 ENOG4105BZ1 (ABC) transporter BAX60_10050 ENOG4105KNA -acetyltransferase BAX60_10065 ENOG4107RUY (E1 component), alpha subunit BAX60_10075 ENOG4107QKR Dehydrogenase BAX60_10085 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BAX60_10090 ENOG41069DP small acid-soluble spore protein BAX60_10095 ENOG4105KK4 UPF0060 membrane protein BAX60_10120 ENOG4105F8D glycoside hydrolase family 4 BAX60_10125 ENOG4108Q3X Transcriptional regulator BAX60_10130 ENOG4105CI1 PTS System BAX60_10135 ENOG4105BZ1 (ABC) transporter BAX60_10140 ENOG4105BZ1 (ABC) transporter BAX60_10150 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAX60_10155 ENOG4105BZU Histidine kinase BAX60_10160 ENOG4105WH1 Two component transcriptional regulator luxr family BAX60_10165 ENOG4105CJ1 ABC, transporter BAX60_10170 ENOG41090VJ ABC-2 type transporter BAX60_10175 ENOG4108KYE ABC-2 type transporter BAX60_10185 ENOG4105U3E Transcriptional regulator BAX60_10190 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold BAX60_10195 ENOG4105H93 Acyltransferase family BAX60_10200 ENOG4108YYS metal-dependent hydrolase (By similarity) BAX60_10205 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAX60_10210 ENOG410834F Transcriptional regulator BAX60_10220 ENOG4108MES Periplasmic binding protein BAX60_10225 ENOG4105DQ5 transport system permease protein BAX60_10230 ENOG4108IHU transport system permease protein BAX60_10235 ENOG4105JAB phenazine biosynthesis protein, phzf family BAX60_10240 ENOG4107Y03 Nitroreductase BAX60_10255 ENOG4105ECP epimerase BAX60_10275 ENOG4105F27 Major Facilitator BAX60_10295 ENOG4106AKJ BAX60_10300 ENOG4105D74 hydrolase BAX60_10305 ENOG4105CKK Glycosyl transferase, family 2 BAX60_10310 ENOG4105EJV Membrane BAX60_10315 ENOG41067AE Membrane-bound metal-dependent hydrolase BAX60_10320 ENOG4105CEN a g-specific adenine glycosylase BAX60_10325 ENOG4106BXE BAX60_10330 ENOG4105CAN Short-chain dehydrogenase reductase Sdr BAX60_10345 ENOG4105EVI UPF0374 protein BAX60_10350 ENOG4105BZ1 (ABC) transporter BAX60_10355 ENOG4107NBY Membrane BAX60_10365 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAX60_10370 ENOG4105G5W regulator Fur family BAX60_10485 ENOG4108N23 SpoOM-related protein BAX60_10505 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BAX60_10520 ENOG4105E2Y ABC, transporter BAX60_10525 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BAX60_10530 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BAX60_10535 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BAX60_10545 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BAX60_10550 ENOG4107D63 BAX60_10555 ENOG4105VZ8 Transcriptional regulator BAX60_10570 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BAX60_10580 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BAX60_10600 ENOG4105CYN Serine protein kinase BAX60_10605 ENOG4106AKX UPF0229 protein BAX60_10615 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BAX60_10620 ENOG4105CW7 secretion protein, HlyD family BAX60_10625 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAX60_10630 ENOG4105CS1 NAD(P)H quinone oxidoreductase BAX60_10645 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAX60_10650 ENOG4105CZV ABC transporter BAX60_10655 ENOG4105CJ1 ABC, transporter BAX60_10660 ENOG4108TU7 Inherit from COG: (ABC) transporter BAX60_10665 ENOG4105VEQ Cold shock protein BAX60_10680 ENOG4105BZU Histidine kinase BAX60_10720 ENOG4108YBP pseudouridine synthase BAX60_10730 ENOG41080XP Cbs domain BAX60_10735 ENOG4107YBY Hydrolase BAX60_10740 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BAX60_10750 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAX60_10755 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAX60_10765 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BAX60_10770 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BAX60_10780 ENOG4105BZU Histidine kinase BAX60_10785 ENOG4105WH1 Two component transcriptional regulator luxr family BAX60_10820 ENOG4105ED1 spovr family BAX60_10825 ENOG4105G6Z alkaline phosphatase BAX60_10840 ENOG4105BZN citrate synthase BAX60_10845 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BAX60_10850 ENOG4105CUB amino acid BAX60_10855 ENOG4105C8J )-transporter BAX60_10860 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAX60_10875 ENOG4105J37 BAX60_10880 ENOG4108AEY RNA polymerase sigma factor BAX60_10885 ENOG4108FN7 Aldo keto reductase BAX60_10890 ENOG4105F6E Acyl-transferase BAX60_10895 ENOG4107VFR oxidoreductase BAX60_10905 ENOG4105C37 (CBS) domain BAX60_10915 ENOG4105CHM Aminotransferase BAX60_10920 ENOG4105C37 (CBS) domain BAX60_10930 ENOG4105WMR Protein CrcB homolog BAX60_10935 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAX60_10945 ENOG4105D64 Mechanosensitive ion channel BAX60_10950 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BAX60_10955 ENOG4107VMI polysaccharide deacetylase BAX60_10960 ENOG4105F0I Aminotransferase BAX60_10980 ENOG4105BZ1 (ABC) transporter BAX60_10985 ENOG4105BZ1 (ABC) transporter BAX60_11010 ENOG410839P BAX60_11020 ENOG4106MP8 UPF0754 membrane protein BAX60_11025 ENOG4105WZB UPF0342 protein BAX60_11030 ENOG4105F1N DNA alkylation repair BAX60_11040 ENOG4105D4P Coproporphyrinogen iii oxidase BAX60_11045 ENOG4107S91 Sodium hydrogen exchanger BAX60_11050 ENOG4105NCW Trka-c domain protein BAX60_11060 ENOG4105CGU Enoyl-CoA hydratase BAX60_11070 ENOG4108IUX (ABC) transporter BAX60_11075 ENOG4105RHA ABC transporter, permease BAX60_11080 ENOG4107VRP DNA repair exonuclease BAX60_11085 ENOG4106D4I domain protein BAX60_11090 ENOG4105EQI Metal Dependent Phosphohydrolase BAX60_11100 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAX60_11145 ENOG4105NBU tryptophan transport protein BAX60_11150 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BAX60_11155 ENOG4105K59 histidine triad (HIT) protein BAX60_11190 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BAX60_11195 ENOG4105BZ4 penicillin-binding protein BAX60_11200 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BAX60_11205 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BAX60_11210 ENOG4105C1Q protoporphyrinogen oxidase BAX60_11220 ENOG4105ECB domain protein BAX60_11230 ENOG41090T1 Membrane BAX60_11240 ENOG4105DER m42 family BAX60_11255 ENOG4106AXD BAX60_11260 ENOG4108RQ5 Beta-lactamase domain-containing protein BAX60_11265 ENOG4105DF9 Lipoate-protein, ligase BAX60_11275 ENOG4105CEY Amp-dependent synthetase and ligase BAX60_11285 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BAX60_11290 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BAX60_11295 ENOG4105KD7 acetyltransferase BAX60_11305 ENOG4108HUF Transporter BAX60_11310 ENOG4107TB6 phosphoglycerate mutase BAX60_11320 ENOG4107F3J Amp-dependent synthetase and ligase BAX60_11325 ENOG4107ZYJ bioY protein BAX60_11330 ENOG4106YBV Methyl-accepting chemotaxis BAX60_11350 ENOG4105XVF Competence transcription factor BAX60_11355 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BAX60_11360 ENOG4105X3H Excalibur domain protein BAX60_11365 ENOG4105E1V na solute symporter BAX60_11370 ENOG4106CAD Protein of unknown function (DUF3311) BAX60_11375 ENOG41060YP BAX60_11390 ENOG4107SCK Monooxygenase BAX60_11395 ENOG4108INS Transcriptional regulator BAX60_11415 ENOG4105TRI Hydrolase BAX60_11430 ENOG4108KK1 membrane protein AbrB duplication BAX60_11435 ENOG4106K7D Major facilitator family transporter BAX60_11440 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BAX60_11445 ENOG4105VWP Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding BAX60_11460 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BAX60_11470 ENOG4105EYH Exonuclease BAX60_11520 ENOG4105ERH Fumarylacetoacetate hydrolase BAX60_11530 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BAX60_11540 ENOG4105CAQ asparagine synthetase BAX60_11550 ENOG4105UQX Mate efflux family protein BAX60_11555 ENOG4106HBX Transcriptional Regulator AraC Family BAX60_11560 ENOG4105ETE Transcriptional regulator (LacI family BAX60_11565 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BAX60_11570 ENOG4105SF0 DinB family BAX60_11575 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BAX60_11580 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAX60_11585 ENOG4105MYW Pentapeptide repeat protein BAX60_11590 ENOG4107S9D Alpha beta hydrolase BAX60_11595 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BAX60_11600 ENOG4107RIQ Sulfate adenylate transferase BAX60_11605 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) BAX60_11610 ENOG4108N5B 2-phosphosulfolactate phosphatase BAX60_11615 ENOG41061P3 phosphosulfolactate synthase BAX60_11625 ENOG4105DIA mandelate racemase muconate lactonizing BAX60_11630 ENOG4107RCC Major Facilitator Superfamily BAX60_11635 ENOG4108SZE gCN5-related N-acetyltransferase BAX60_11640 ENOG4105MA6 gCN5-related N-acetyltransferase BAX60_11650 ENOG4108VPT UPF0234 protein BAX60_11655 ENOG4105QNR S1 RNA binding domain protein BAX60_11660 ENOG410751J BAX60_11665 ENOG4105EPR degv family BAX60_11670 ENOG4107AYK membrAne BAX60_11680 ENOG41073B9 BAX60_11690 ENOG4108KP7 hydrolase BAX60_11695 ENOG4108MXZ Esterase BAX60_11700 ENOG4105VG1 fes assembly suf system protein BAX60_11710 ENOG4105IQ5 FAD linked oxidase domain protein BAX60_11720 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BAX60_11735 ENOG4105C8Y Acetylornithine aminotransferase BAX60_11740 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAX60_11750 ENOG4105DBV ornithine carbamoyltransferase BAX60_11775 ENOG4107RMD Basic membrane lipoprotein BAX60_11790 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAX60_11795 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAX60_11805 ENOG4105C3U ABC transporter BAX60_11810 ENOG4108JQ7 (ABC) transporter BAX60_11825 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAX60_11835 ENOG4105C31 Tryptophanyl-tRNA synthetase BAX60_11845 ENOG4108J59 Extracellular solute-binding protein, family 5 BAX60_11850 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAX60_11855 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAX60_11865 ENOG4108JQ7 (ABC) transporter BAX60_11880 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) BAX60_11890 ENOG4108ZCF integral membrane protein BAX60_11895 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis BAX60_11905 ENOG4105DPN Oligoendopeptidase f BAX60_11920 ENOG4105T58 Dithiol-disulfide isomerase BAX60_11925 ENOG4108Z18 K06886 hemoglobin BAX60_11930 ENOG4105E4C Lytic transglycosylase catalytic BAX60_11935 ENOG4105MIX Adenylate cyclase BAX60_11950 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAX60_11955 ENOG4105EMS pseudouridine synthase BAX60_11970 ENOG4105ETU transcriptional activator (TenA BAX60_11975 ENOG4108VEU Thiamine monophosphate synthase BAX60_11990 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) BAX60_11995 ENOG4105D06 uba thif-type nad fad binding protein BAX60_12000 ENOG4105DWF phosphomethylpyrimidine kinase BAX60_12005 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BAX60_12010 ENOG4107A88 BAX60_12065 ENOG4105ENA helicase BAX60_12080 ENOG4108ZMI UPF0477 protein BAX60_12090 ENOG4105C28 cystathionine BAX60_12095 ENOG4105C28 cystathionine BAX60_12100 ENOG4105D9U N-acetyltransferase BAX60_12105 ENOG4105JHY Membrane BAX60_12170 ENOG4105DM4 PTS System BAX60_12175 ENOG4105DG6 mannose-6-phosphate isomerase BAX60_12185 ENOG4105VMI -acetyltransferase BAX60_12195 ENOG4108Z66 YbaK ebsC protein BAX60_12210 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BAX60_12220 ENOG4108ZJ4 polysaccharide deacetylase BAX60_12225 ENOG4107CUJ Protein of unknown function (DUF2690) BAX60_12255 ENOG4108IEG Formate dehydrogenase Alpha subunit BAX60_12280 ENOG4106A3M Cytochrome p-450 BAX60_12285 ENOG41087PP glycosyltransferase MGT family BAX60_12295 ENOG4105EXQ uroporphyrinogen iii synthase hem4 BAX60_12300 ENOG4105C4B ABC transporter, permease BAX60_12305 ENOG4108IXI (ABC) transporter BAX60_12315 ENOG4105Q95 Cupin 2, conserved barrel domain protein BAX60_12330 ENOG4105D2H Uronic isomerase BAX60_12335 ENOG4105CT4 transporter BAX60_12340 ENOG4105DG4 malate L-lactate dehydrogenase BAX60_12345 ENOG4105CPQ Dehydrogenase BAX60_12350 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) BAX60_12355 ENOG4105DMW Dehydrogenase reductase BAX60_12360 ENOG4108I5G Major Facilitator superfamily BAX60_12365 ENOG4107KJX Transcriptional regulator BAX60_12370 ENOG4107QZW Altronate oxidoreductase BAX60_12375 ENOG4105CTX dehydratase BAX60_12380 ENOG4107TSN permease BAX60_12390 ENOG4105JD4 ATPase yjob BAX60_12405 ENOG41068K0 YCII-related domain BAX60_12410 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAX60_12415 ENOG4105KWG Pfam:DUF1696 BAX60_12420 ENOG4105K7W phage-related replication protein BAX60_12425 ENOG4105WEF catalase BAX60_12430 ENOG410635T phage-like element pbsx protein BAX60_12480 ENOG4108TFU terminase (Small subunit) BAX60_12485 ENOG4105IG6 Phage terminase, large subunit BAX60_12490 ENOG4108MDF Phage Portal Protein BAX60_12515 ENOG41060SN BAX60_12530 ENOG4105PQS phage protein BAX60_12535 ENOG4105FR7 XkdM protein, phage-like element PBSX BAX60_12540 ENOG4105MTC XkdN-like protein BAX60_12550 ENOG4108FKH Transglycosylase SLT domain BAX60_12555 ENOG4108WZM domain protein BAX60_12560 ENOG4105X7F BAX60_12570 ENOG4105MFU Protein of unknown function (DUF2634) BAX60_12575 ENOG41066EA baseplate J family protein BAX60_12580 ENOG410906S phage-like element pbsx protein xkdt BAX60_12590 ENOG41068G1 BAX60_12620 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAX60_12635 ENOG4105CJ3 phosphate transporter BAX60_12640 ENOG4107GRR phosphate transport regulator BAX60_12645 ENOG4107R7I amino acid BAX60_12655 ENOG4105EDW glycosyl transferase, family 39 BAX60_12660 ENOG4105CKK Glycosyl transferase, family 2 BAX60_12670 ENOG4105C0H protease BAX60_12680 ENOG4108ME1 Peptidase M55 D-aminopeptidase BAX60_12685 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAX60_12690 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAX60_12695 ENOG4105C3U ABC transporter BAX60_12705 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAX60_12710 ENOG4105DTQ mandelate racemase muconate lactonizing BAX60_12715 ENOG4107SN7 NLP P60 protein BAX60_12720 ENOG4108JQ7 (ABC) transporter BAX60_12725 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BAX60_12730 ENOG4107TUM Amidinotransferase BAX60_12735 ENOG4108S4H thioesterase Superfamily protein BAX60_12740 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAX60_12760 ENOG4108428 Inherit from COG: -acetyltransferase BAX60_12770 ENOG41080TC multidrug resistance protein BAX60_12775 ENOG4105CIY formyltetrahydrofolate deformylase BAX60_12780 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BAX60_12795 ENOG4105K56 Transcriptional regulator BAX60_12800 ENOG4108ZHJ Organic hydroperoxide resistance protein BAX60_12805 ENOG4107TVC Glycosyl transferase, family 2 BAX60_12810 ENOG4107Y2X deaminase BAX60_12820 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BAX60_12825 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BAX60_12835 ENOG4108W7F transporter, permease BAX60_12840 ENOG4108JJB ABC transporter BAX60_12845 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein BAX60_12850 ENOG4108X43 YKOF domain protein BAX60_12855 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAX60_12860 ENOG41062D9 Histidine kinase BAX60_12870 ENOG4106849 propeptide, pepSY amd peptidase M4 BAX60_12885 ENOG4105CJW magnesium transporter BAX60_12890 ENOG4105V75 Transcriptional regulator BAX60_12935 ENOG4105DQE DNA ligase BAX60_12940 ENOG4105FDF Could be involved in DNA repair (By similarity) BAX60_12950 ENOG4107T5V SNARE associated Golgi BAX60_12955 ENOG4107TS3 membrane protein, TerC BAX60_12960 ENOG4108WZW RNA polymerase sigma BAX60_12970 ENOG410681C small acid-soluble spore protein BAX60_12980 ENOG4105D0M Protease HtpX homolog BAX60_13000 ENOG4108TGC Acyltransferase BAX60_13005 ENOG4105BZU Histidine kinase BAX60_13010 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAX60_13020 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BAX60_13025 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BAX60_13030 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BAX60_13040 ENOG4107T6J Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit BAX60_13045 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) BAX60_13050 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAX60_13055 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BAX60_13075 ENOG4105BZU Histidine kinase BAX60_13085 ENOG41090MY MarR family Transcriptional regulator BAX60_13090 ENOG4105ER2 Ompa motb domain protein BAX60_13095 ENOG4105E14 MotA TolQ exbB proton channel BAX60_13105 ENOG4108K88 Membrane BAX60_13110 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BAX60_13115 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase BAX60_13120 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BAX60_13125 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) BAX60_13130 ENOG4105FEA Spore maturation protein BAX60_13165 ENOG4105F0V Cell wall hydrolase BAX60_13180 ENOG4105C59 p-type ATPase BAX60_13190 ENOG4105DC7 peptidase M24 BAX60_13205 ENOG4105CID antiterminator BAX60_13215 ENOG4105KRI phosphocarrier protein (HPr BAX60_13220 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BAX60_13230 ENOG4105F6S Spore photoproduct lyase BAX60_13240 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAX60_13245 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAX60_13250 ENOG4105K4I Scp-like extracellular BAX60_13260 ENOG4105BZU Histidine kinase BAX60_13265 ENOG4105CHM Aminotransferase BAX60_13275 ENOG4107R88 Chemotaxis protein (CheV) BAX60_13280 ENOG4105UIN BAX60_13290 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein BAX60_13300 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BAX60_13305 ENOG4105EPM Diguanylate phosphodiesterase BAX60_13310 ENOG4107IN1 Protein of unknown function (DUF1797) BAX60_13315 ENOG4108XRC Protein of unknown function (DUF458) BAX60_13345 ENOG4105NQC Flavodoxin BAX60_13355 ENOG4105CH2 amidohydrolase BAX60_13365 ENOG4105D8X mechanosensitive ion channel BAX60_13370 ENOG4105D3R alkyl hydroperoxide reductase BAX60_13375 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAX60_13390 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) BAX60_13395 ENOG4105D06 uba thif-type nad fad binding protein BAX60_13400 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAX60_13405 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BAX60_13410 ENOG4108ZAF Molybdopterin BAX60_13415 ENOG41067WU Molybdopterin converting factor (Subunit 1) BAX60_13420 ENOG4105BZ1 (ABC) transporter BAX60_13425 ENOG4105BZ1 (ABC) transporter BAX60_13435 ENOG4107X8C Efflux transporter RND family MFP subunit BAX60_13440 ENOG4105C19 ABC transporter BAX60_13445 ENOG4107RBB ABC transporter, permease BAX60_13450 ENOG4105E98 transcriptional regulator DeoR family BAX60_13455 ENOG4105DE4 1-phosphofructokinase BAX60_13460 ENOG4105DM4 PTS System BAX60_13465 ENOG4105C3F Signal peptidase i BAX60_13475 ENOG4105C5H ABC transporter BAX60_13480 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BAX60_13505 ENOG4105BZU Histidine kinase BAX60_13515 ENOG4107ZYR domain protein BAX60_13525 ENOG4105CN5 Metallo-Beta-Lactamase BAX60_13535 ENOG4108X4Q Hydrolase BAX60_13540 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAX60_13560 ENOG4105CPP Dehydrogenase, E1 component BAX60_13565 ENOG4105C7S Dehydrogenase BAX60_13570 ENOG4107QN2 dihydrolipoyl dehydrogenase BAX60_13585 ENOG4105CXN decarboxylase BAX60_13590 ENOG4105WBI UPF0223 protein BAX60_13605 ENOG4105ECY inositol monophosphatase BAX60_13615 ENOG4105JQZ Methyltransferase BAX60_13655 ENOG4105CI3 gtp-binding protein typa BAX60_13660 ENOG4105QA2 BAX60_13675 ENOG4108IAB Phoh family BAX60_13685 ENOG4105CSV Glutaminase BAX60_13690 ENOG4105ZPI UPF0358 protein BAX60_13695 ENOG4105CNI cell division protein FtsW BAX60_13700 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BAX60_13715 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BAX60_13725 ENOG4105BZ9 Cytochrome C oxidase, subunit I BAX60_13730 ENOG4105CCU oxidase (Subunit III) BAX60_13735 ENOG41064X9 cytochrome C oxidase subunit IV BAX60_13750 ENOG41080XQ Signal transduction protein with cbs domains BAX60_13755 ENOG4106UY4 Inherit from COG: Scp-like extracellular BAX60_13775 ENOG4105WUC UPF0298 protein BAX60_13780 ENOG4106H78 methyltransferase BAX60_13785 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) BAX60_13790 ENOG4105H20 Sporulation integral membrane protein YlbJ BAX60_13795 ENOG4105D78 K07001 NTE family protein BAX60_13800 ENOG41063PX domain protein BAX60_13805 ENOG4105CDE UPF0348 protein BAX60_13815 ENOG4105KNH Nucleic acid-binding protein BAX60_13820 ENOG41067VY 50S ribosomal protein L32 BAX60_13845 ENOG4108V6E Cell division protein mraZ BAX60_13850 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) BAX60_13860 ENOG4105CJN penicillin-binding protein BAX60_13870 ENOG4105CJN penicillin-binding protein BAX60_13875 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAX60_13885 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) BAX60_13890 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BAX60_13895 ENOG4105CNI cell division protein FtsW BAX60_13900 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAX60_13905 ENOG4105D4A Cell wall formation (By similarity) BAX60_13910 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BAX60_13915 ENOG4108R2U division initiation protein BAX60_13925 ENOG4105K67 small basic protein BAX60_13930 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BAX60_13935 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BAX60_13945 ENOG4105FFI sigma-e processing peptidase spoiiga BAX60_13950 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAX60_13960 ENOG4105DKW ABC transporter BAX60_13970 ENOG4105WR5 sporulation protein, YlmC YmxH family BAX60_13975 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BAX60_13980 ENOG4105DFA alanine racemase domain protein BAX60_13985 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) BAX60_13990 ENOG41067XK integral membrane protein BAX60_13995 ENOG4105DBK s4 domain protein BAX60_14005 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAX60_14015 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) BAX60_14020 ENOG4105C34 Pseudouridine synthase BAX60_14025 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) BAX60_14035 ENOG4105CXT aspartate transcarbamylase BAX60_14045 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAX60_14050 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BAX60_14055 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BAX60_14060 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) BAX60_14065 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) BAX60_14070 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BAX60_14075 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) BAX60_14085 ENOG4107S4M Sulfate adenylate transferase BAX60_14090 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BAX60_14095 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAX60_14100 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAX60_14105 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAX60_14110 ENOG4105F23 Fibronectin-binding protein BAX60_14120 ENOG4105DSJ YicC domain protein BAX60_14125 ENOG4105KC4 UPF0296 protein BAX60_14130 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BAX60_14140 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BAX60_14145 ENOG4105C25 Primosomal protein n' BAX60_14150 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAX60_14155 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BAX60_14160 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BAX60_14165 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BAX60_14170 ENOG4108ZF3 Phosphatase BAX60_14175 ENOG4105D9P serine threonine protein kinase BAX60_14180 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BAX60_14185 ENOG4105DJV ribulose-phosphate 3-epimerase BAX60_14190 ENOG4105FJ0 thiamine BAX60_14200 ENOG4105VB9 50S ribosomal protein l28 BAX60_14205 ENOG4108ZAA Alkaline-shock protein BAX60_14210 ENOG4105DP4 dak2 domain fusion protein ylov BAX60_14220 ENOG4105EJQ L-serine dehydratase BAX60_14225 ENOG4105CB5 ATP-dependent DNA helicase recG BAX60_14230 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) BAX60_14240 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAX60_14245 ENOG4105CHR reductase BAX60_14250 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BAX60_14255 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BAX60_14260 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BAX60_14265 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BAX60_14275 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) BAX60_14285 ENOG4105K5M 30s ribosomal protein S16 BAX60_14290 ENOG4108BW8 UPF0109 protein BAX60_14300 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) BAX60_14305 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) BAX60_14310 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) BAX60_14315 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BAX60_14320 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BAX60_14330 ENOG4105VM1 flagellar BAX60_14335 ENOG4105CMV Succinyl-CoA synthetase subunit beta BAX60_14340 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BAX60_14345 ENOG4105C79 DNA protecting protein DprA BAX60_14350 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAX60_14355 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) BAX60_14360 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAX60_14365 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) BAX60_14370 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) BAX60_14380 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BAX60_14385 ENOG4108ZC9 flagellar basal-body rod protein flgc BAX60_14390 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BAX60_14395 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BAX60_14400 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAX60_14415 ENOG4106YF4 Flagellar biosynthesis chaperone BAX60_14425 ENOG410696Y Flagellar hook-length control protein BAX60_14430 ENOG410822I Flagellar hook capping protein BAX60_14435 ENOG4108JQA flagellar BAX60_14440 ENOG41068WV flagellar FlbD family protein BAX60_14450 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAX60_14455 ENOG4105DD5 Flagellar motor switch protein BAX60_14460 ENOG4107YTP response regulator receiver protein BAX60_14470 ENOG4105CN7 Flagellar biosynthetic protein FliP BAX60_14475 ENOG4105VS8 Flagellar biosynthetic protein fliq BAX60_14480 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BAX60_14485 ENOG4105D00 flagellar biosynthetic protein flhB BAX60_14490 ENOG4105D7B Flagellar biosynthesis protein flha BAX60_14495 ENOG4105FZW flagellar biosynthesis regulator FlhF BAX60_14505 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BAX60_14510 ENOG4105CBS Chea signal transduction histidine kinase BAX60_14515 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis BAX60_14530 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAX60_14540 ENOG4105CE9 30S ribosomal protein S2 BAX60_14545 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) BAX60_14555 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) BAX60_14560 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BAX60_14565 ENOG4105KNE Phosphatidate cytidylyltransferase BAX60_14575 ENOG4105DZP Membrane-associated zinc metalloprotease BAX60_14580 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BAX60_14585 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAX60_14590 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) BAX60_14595 ENOG4105CHV Transcription elongation factor NusA BAX60_14600 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BAX60_14605 ENOG4105VHM ribosomal protein BAX60_14610 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) BAX60_14615 ENOG4105W7A Protein of unknown function (DUF503) BAX60_14620 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) BAX60_14625 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BAX60_14630 ENOG4105DTN riboflavin biosynthesis protein ribF BAX60_14635 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) BAX60_14640 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) BAX60_14650 ENOG4105C1V Peptidase, M16 BAX60_14660 ENOG4105E35 Dipicolinate synthase subunit A BAX60_14665 ENOG4108S0H Dipicolinic acid synthetase, b subunit BAX60_14670 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAX60_14680 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAX60_14690 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BAX60_14700 ENOG4105CNU cell division protein FtsK BAX60_14705 ENOG4105FDP GntR family transcriptional regulator BAX60_14725 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BAX60_14730 ENOG4105XZV Protein of unknown function (DUF3243) BAX60_14745 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BAX60_14750 ENOG4105CEV competence damage-inducible protein BAX60_14760 ENOG4108A04 Beta-lactamase BAX60_14765 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) BAX60_14770 ENOG4105D48 metallophosphoesterase BAX60_14775 ENOG4105MCT stage V sporulation protein S BAX60_14785 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAX60_14790 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAX60_14805 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) BAX60_14810 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BAX60_14825 ENOG4105IIP Membrane BAX60_14830 ENOG4105W1N transcriptional regulator BAX60_14835 ENOG4108151 Beta-lactamase domain protein BAX60_14845 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAX60_14855 ENOG4107QKG PfaD family BAX60_14860 ENOG41062T2 Acyl carrier protein BAX60_14865 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase BAX60_14870 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BAX60_14875 ENOG4108MGH Enoyl-CoA hydratase BAX60_14880 ENOG4108KQ6 Enoyl-CoA hydratase BAX60_14885 ENOG4105C0W non-ribosomal peptide synthetase BAX60_14890 ENOG4107SQU synthase BAX60_14900 ENOG4105C0W non-ribosomal peptide synthetase BAX60_14910 ENOG4106A3M Cytochrome p-450 BAX60_14925 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BAX60_14935 ENOG4105K7W phage-related replication protein BAX60_14940 ENOG4108X3M OsmC Ohr family protein BAX60_14965 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) BAX60_14970 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BAX60_14985 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BAX60_14990 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAX60_14995 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAX60_15000 ENOG4105U6W MutT NUDIX family protein BAX60_15005 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAX60_15010 ENOG4106F1P AAA ATPase, central domain protein BAX60_15020 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAX60_15025 ENOG4105CXI aluminum resistance protein BAX60_15030 ENOG4105KV4 Transcriptional regulator BAX60_15035 ENOG4105C5F glutamine synthetase BAX60_15045 ENOG410907G BAX60_15065 ENOG4105CT4 transporter BAX60_15070 ENOG4105DSG hydrolase family 43 BAX60_15085 ENOG4105CMG Carbohydrate kinase BAX60_15100 ENOG4105C54 Major Facilitator superfamily BAX60_15105 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAX60_15115 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BAX60_15180 ENOG4105CAH Chromate BAX60_15190 ENOG4108Q8B Spore germination protein BAX60_15195 ENOG4108NHD germination protein BAX60_15210 ENOG4105FVX BAX60_15220 ENOG4105K7W phage-related replication protein BAX60_15230 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BAX60_15245 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BAX60_15255 ENOG4108SVB resolvase BAX60_15260 ENOG4105VPS UPF0291 protein BAX60_15265 ENOG4105CV1 Transketolase (EC 2.2.1.1) BAX60_15285 ENOG4107QIV Cytochrome c biogenesis protein BAX60_15310 ENOG4107DZX Small, acid-soluble spore protein P BAX60_15320 ENOG4108I0Z Aconitate hydratase BAX60_15325 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAX60_15340 ENOG41067CD Small, acid-soluble spore protein Tlp BAX60_15350 ENOG4105MI2 BAX60_15355 ENOG4105W8X HesB YadR YfhF-family protein BAX60_15360 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BAX60_15365 ENOG4105K4P CoA-binding domain protein BAX60_15370 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAX60_15395 ENOG4107QWR cellulase (EC 3.2.1.4) BAX60_15405 ENOG4108MYR Secreted protein BAX60_15410 ENOG4107SYN Glycosyl hydrolases family 43 BAX60_15420 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAX60_15425 ENOG4107T5V SNARE associated Golgi BAX60_15435 ENOG4107QX3 carboxylase BAX60_15440 ENOG4105E39 Enoyl-CoA hydratase BAX60_15445 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BAX60_15450 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BAX60_15455 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAX60_15460 ENOG4105CEY Amp-dependent synthetase and ligase BAX60_15465 ENOG4105C1G acyl-Coa dehydrogenase BAX60_15475 ENOG41062JF Transcriptional regulator BAX60_15485 ENOG4105F32 YngK protein BAX60_15490 ENOG4106U2H Protein of unknown function (DUF1360) BAX60_15515 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family BAX60_15520 ENOG4108N2V aldose 1-epimerase BAX60_15525 ENOG4107QJQ Mate efflux family protein BAX60_15550 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BAX60_15555 ENOG4105SKE transcriptional Regulator LysR family BAX60_15560 ENOG4105CB2 alcohol dehydrogenase BAX60_15565 ENOG4105BZ8 glutamate synthase BAX60_15570 ENOG4105CBC glutamate synthase BAX60_15575 ENOG4105C5Q Transcriptional regulator BAX60_15580 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BAX60_15605 ENOG4105DQ6 Transposase BAX60_15620 ENOG4108UB7 BAX60_15625 ENOG41068WN BAX60_15650 ENOG4105IE8 Alpha-ketoglutarate permease BAX60_15655 ENOG4107U6E carbohydrate kinase FGGY BAX60_15660 ENOG4108M3J Dehydrogenase BAX60_15665 ENOG4108J2R molybdopterin oxidoreductase BAX60_15695 ENOG4105EC8 Methyl-accepting chemotaxis BAX60_15705 ENOG4108YQE rare lipoprotein a BAX60_15710 ENOG4105XPP Protein of unknown function (DUF1275) BAX60_15715 ENOG4108NR7 pectate lyase BAX60_15720 ENOG4105CHR reductase BAX60_15735 ENOG4108RAV Conserved protein BAX60_15745 ENOG4105F0F Oxalate decarboxylase BAX60_15775 ENOG41073R8 VanW family BAX60_15785 ENOG4105VMP Transcriptional regulator BAX60_15790 ENOG4105NX3 Membrane BAX60_15800 ENOG4108Q5Y Membrane BAX60_15825 ENOG4108V4B ThiJ pfpI BAX60_15830 ENOG4108J4B Beta-lactamase BAX60_15840 ENOG4108M1A Chitin-binding protein BAX60_15855 ENOG4107T94 Endo-14-beta-xylanase BAX60_15865 ENOG4108RZ2 Glycoside hydrolase family 16 BAX60_15870 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAX60_15890 ENOG4105ST3 Transcriptional regulator BAX60_15900 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) BAX60_15905 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) BAX60_15910 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAX60_15925 ENOG4105ETE Transcriptional regulator (LacI family BAX60_15935 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BAX60_15940 ENOG4105DRS transport system, permease BAX60_15950 ENOG4108HKT sucrose-6-phosphate hydrolase BAX60_15960 ENOG4108UW5 maltose o-acetyltransferase BAX60_16025 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAX60_16065 ENOG4106ANW SMI1_KNR4 BAX60_16070 ENOG4106BHF BAX60_16085 ENOG4108Z7R Chaperone CsaA BAX60_16090 ENOG4105FTV AraC Family Transcriptional Regulator BAX60_16095 ENOG4108HJF gCN5-related N-acetyltransferase BAX60_16105 ENOG4108W8B Beta-lactamase domain protein BAX60_16115 ENOG4105D29 Helix-turn-helix type 11 domain protein BAX60_16125 ENOG4105KTU Transcriptional regulator, arsr family BAX60_16135 ENOG4108SJC Membrane BAX60_16155 ENOG4105ECK Fatty Acid Desaturase BAX60_16160 ENOG4108ZGX Histidine kinase BAX60_16165 ENOG4108S01 response regulator BAX60_16170 ENOG4107RUZ Sss sodium solute transporter superfamily BAX60_16175 ENOG41069ER domain protein BAX60_16180 ENOG4105C9U ATP-dependent DNA helicase RecQ BAX60_16190 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAX60_16195 ENOG4105SCY DNAK suppressor BAX60_16210 ENOG4105C26 Dehydrogenase BAX60_16215 ENOG4105EWU Squalene--hopene cyclase BAX60_16220 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAX60_16225 ENOG4105C8J )-transporter BAX60_16230 ENOG4105C09 Bile acid BAX60_16235 ENOG4105C7S Dehydrogenase BAX60_16245 ENOG4107T89 von Willebrand factor, type A BAX60_16250 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BAX60_16260 ENOG4105K4H Nlp p60 protein BAX60_16265 ENOG41087PP glycosyltransferase MGT family BAX60_16275 ENOG4107QMU Mate efflux family protein BAX60_16280 ENOG4106SCS STAS domain BAX60_16300 ENOG4105FR1 rard protein BAX60_16315 ENOG4105C6Z Gluconate BAX60_16320 ENOG41090U3 tautomerase BAX60_16340 ENOG4105FBA Phospholipase Carboxylesterase BAX60_16355 ENOG4105E1V na solute symporter BAX60_16375 ENOG4108VXD carboxy-peptidase BAX60_16380 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BAX60_16390 ENOG4106Z5R BAX60_16395 ENOG410841Q phosphoesterase PA-phosphatase related protein BAX60_16430 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BAX60_16435 ENOG4108TSC N-acetyltransferase BAX60_16440 ENOG4107S4Y M20 DapE family protein YgeY BAX60_16455 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAX60_16495 ENOG4107T32 3-phytase (EC 3.1.3.8) BAX60_16500 ENOG4105C5E polysaccharide biosynthesis protein BAX60_16505 ENOG4105E0X reductase BAX60_16510 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BAX60_16530 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) BAX60_16535 ENOG41090WU lipolytic protein G-D-S-L family BAX60_16540 ENOG4108KF3 Electron transport protein SCO1 SenC BAX60_16555 ENOG4105C7B Threonine dehydratase BAX60_16565 ENOG4108UT2 hemolysin iii BAX60_16575 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BAX60_16595 ENOG4107YX5 Pfam:DUF548 BAX60_16600 ENOG4108Y6J UPF0403 protein BAX60_16605 ENOG4105C01 Dihydroxy-acid dehydratase BAX60_16620 ENOG4108V06 Glutathione peroxidase BAX60_16625 ENOG4105CVG Homoserine O-transsuccinylase BAX60_16665 ENOG41081VK Ribonuclease BAX60_16690 ENOG410890F Dynamin family BAX60_16705 ENOG41065KQ synthase BAX60_16710 ENOG4105C2W permease BAX60_16715 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) BAX60_16720 ENOG4105CTD carboxy-peptidase BAX60_16725 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) BAX60_16730 ENOG4108UHU Aldolase BAX60_16735 ENOG4105D7K pfkb domain protein BAX60_16740 ENOG4108M60 Transcriptional regulator BAX60_16750 ENOG4105CHR reductase BAX60_16755 ENOG4105DVT helicase BAX60_16775 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BAX60_16790 ENOG4108UKS UPF0398 protein BAX60_16805 ENOG4107X2U Inherit from COG: Exonuclease-like protein BAX60_16810 ENOG4108I5C dEAD DEAH box helicase BAX60_16860 ENOG4105BZ4 penicillin-binding protein BAX60_16870 ENOG4105CSM endonuclease III BAX60_16880 ENOG4105C5S asparaginyl-tRNA synthetase BAX60_16885 ENOG4105CHM Aminotransferase BAX60_16895 ENOG4105YAC BAX60_16900 ENOG4105DVT helicase BAX60_16905 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) BAX60_16910 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) BAX60_16915 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BAX60_16925 ENOG4105DJ0 Poly(A) Polymerase BAX60_16930 ENOG4105CPK Glycosyl transferase (Group 1 BAX60_16935 ENOG4105FJR Lmbe family BAX60_16940 ENOG4108Z5K methylglyoxal synthase BAX60_16945 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BAX60_16950 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BAX60_16955 ENOG4108JYZ YitT family BAX60_16975 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BAX60_16995 ENOG41068YB TPR repeat-containing protein BAX60_17000 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BAX60_17010 ENOG4105CIH Imidazole acetol-phosphate transaminase BAX60_17020 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BAX60_17025 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase BAX60_17035 ENOG4108I0Q anthranilate phosphoribosyltransferase BAX60_17040 ENOG4105CRQ synthase (Component I) BAX60_17045 ENOG4105KHN chorismate mutase BAX60_17050 ENOG4105D49 3-dehydroquinate synthase BAX60_17055 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BAX60_17060 ENOG4105BZU Histidine kinase BAX60_17070 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BAX60_17075 ENOG4105EAH synthase BAX60_17080 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BAX60_17085 ENOG4105XXQ heptaprenyl diphosphate synthase component I BAX60_17095 ENOG4105EUJ GTP cyclohydrolase i BAX60_17100 ENOG4105K70 DNA-binding protein BAX60_17105 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BAX60_17120 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase BAX60_17125 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) BAX60_17130 ENOG41065D1 BAX60_17135 ENOG4105S2F BAX60_17150 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) BAX60_17155 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BAX60_17160 ENOG4105CAT Cytidine monophosphate kinase BAX60_17175 ENOG4105MSI germination protein ypeb BAX60_17185 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) BAX60_17190 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BAX60_17205 ENOG4107RGJ metallophosphoesterase BAX60_17220 ENOG4105I7S Abortive infection protein BAX60_17225 ENOG4105C9U ATP-dependent DNA helicase RecQ BAX60_17230 ENOG4105T7X BAX60_17240 ENOG4108SAX Membrane BAX60_17245 ENOG4108JQ1 Dehydrogenase BAX60_17250 ENOG4105FF2 Type I DHQase BAX60_17265 ENOG4105BZU Histidine kinase BAX60_17270 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAX60_17275 ENOG4105CRE cytochrome C BAX60_17280 ENOG4107TWT Cytochrome c biogenesis protein BAX60_17290 ENOG4105FE9 pseudouridine synthase BAX60_17300 ENOG4108JIC nucleoside recognition domain protein BAX60_17305 ENOG4105DZ1 carboxypeptidase BAX60_17315 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) BAX60_17320 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) BAX60_17335 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BAX60_17340 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BAX60_17345 ENOG4108R6K riboflavin synthase, subunit alpha BAX60_17350 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BAX60_17360 ENOG4105C3F Signal peptidase i BAX60_17375 ENOG4105VES Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) BAX60_17385 ENOG4107ZE5 PPIases accelerate the folding of proteins BAX60_17395 ENOG4105PTM secreted protein BAX60_17400 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BAX60_17410 ENOG4105G6R Stage v sporulation protein ae BAX60_17420 ENOG4105CZ3 stage V sporulation protein ad BAX60_17425 ENOG41090VF Stage v sporulation protein ac BAX60_17440 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAX60_17445 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BAX60_17450 ENOG41082AN stage II sporulation protein BAX60_17455 ENOG4105DZ1 carboxypeptidase BAX60_17460 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BAX60_17465 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BAX60_17470 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAX60_17480 ENOG4105I3K Ferric uptake regulator, Fur family BAX60_17485 ENOG4105MZ9 stage II sporulation protein m BAX60_17500 ENOG4105DFD Na H antiporter BAX60_17505 ENOG4108IJ0 Aspartate ammonia-lyase BAX60_17510 ENOG4105HDK L-asparaginase BAX60_17515 ENOG4108IMY Transcriptional regulator BAX60_17525 ENOG4108YZ4 nudix hydrolase BAX60_17535 ENOG4105CPC Aldo Keto reductase BAX60_17550 ENOG4105CNI cell division protein FtsW BAX60_17555 ENOG4105CNI cell division protein FtsW BAX60_17570 ENOG4106HZJ BAX60_17575 ENOG4105RHY Pfam:UPF0157 BAX60_17580 ENOG4105KAC Antibiotic biosynthesis monooxygenase BAX60_17585 ENOG4108XET gCN5-related N-acetyltransferase BAX60_17595 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAX60_17610 ENOG4105E5W Transporter BAX60_17620 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase BAX60_17635 ENOG4108IXY short-chain dehydrogenase reductase BAX60_17640 ENOG41069FQ Metallo-beta-lactamase superfamily BAX60_17645 ENOG4105II7 pyrroline-5-carboxylate reductase BAX60_17655 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAX60_17665 ENOG410861F 50S ribosomal protein L33 BAX60_17670 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BAX60_17675 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAX60_17680 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BAX60_17685 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAX60_17695 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) BAX60_17700 ENOG4108NA0 Uncharacterized conserved protein (COG2071) BAX60_17705 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BAX60_17710 ENOG4108HNZ carboxyl transferase BAX60_17715 ENOG4108ZVT methylmalonyl-coA epimerase BAX60_17725 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BAX60_17730 ENOG4108QEG Membrane BAX60_17735 ENOG4105CDA abc transporter atp-binding protein BAX60_17740 ENOG4105E5Q amino acid AbC transporter BAX60_17745 ENOG4108HW3 (ABC) transporter BAX60_17750 ENOG4108Y6J UPF0403 protein BAX60_17755 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BAX60_17770 ENOG4105C7S Dehydrogenase BAX60_17775 ENOG4105CPP Dehydrogenase, E1 component BAX60_17785 ENOG4105CKM Branched-chain carboxylic acid kinase BAX60_17790 ENOG4107RDP Dehydrogenase BAX60_17800 ENOG4108JUB Transcriptional regulator BAX60_17805 ENOG4106CCJ Protein of unknown function (DUF2627) BAX60_17810 ENOG4105CR4 methylisocitrate lyase BAX60_17815 ENOG4105DXD 2-methylcitrate dehydratase BAX60_17825 ENOG4105C1G acyl-Coa dehydrogenase BAX60_17830 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BAX60_17840 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAX60_17845 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAX60_17860 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAX60_17875 ENOG4107QQR Sporulation BAX60_17885 ENOG4105S1Z Stage IV sporulation protein B BAX60_17890 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BAX60_17895 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BAX60_17900 ENOG4105DX0 Hemolysin A BAX60_17910 ENOG4105CTB Polyprenyl synthetase BAX60_17915 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BAX60_17920 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BAX60_17925 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BAX60_17930 ENOG4105M7K Involved in the transcription termination process (By similarity) BAX60_17935 ENOG4108ZSR alkaline shock protein BAX60_17940 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAX60_17960 ENOG410644B Stage III sporulation protein af BAX60_17970 ENOG4105KQ4 Stage iii sporulation protein ad BAX60_17975 ENOG4108CQH stage III sporulation protein AC BAX60_17980 ENOG4105KR5 Stage iii sporulation protein BAX60_17985 ENOG4105CD2 stage iii sporulation protein aa BAX60_17995 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BAX60_18000 ENOG4105DC7 peptidase M24 BAX60_18005 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BAX60_18015 ENOG4105CBJ Metal-dependent enzyme BAX60_18030 ENOG4105KST dependent repressor BAX60_18035 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BAX60_18040 ENOG4105WZW rhodanese family BAX60_18045 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BAX60_18050 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BAX60_18055 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) BAX60_18060 ENOG4105C0D helicase BAX60_18075 ENOG4108IMY Transcriptional regulator BAX60_18085 ENOG4105VFR signal peptidase BAX60_18145 ENOG41080XP Cbs domain BAX60_18155 ENOG4105C37 (CBS) domain BAX60_18180 ENOG4105C5X domain protein BAX60_18205 ENOG4105E0M Sulfatase BAX60_18220 ENOG4107ZXI Rhomboid family BAX60_18230 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BAX60_18235 ENOG4105WDJ 50S ribosomal protein L33 BAX60_18255 ENOG41068DG YceG-like family BAX60_18260 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BAX60_18265 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BAX60_18270 ENOG4105E2Z phosphate ABC transporter (Permease BAX60_18275 ENOG4105C8U phosphate abc transporter BAX60_18280 ENOG4105CVA phosphate BAX60_18285 ENOG4107RF6 penicillin-binding protein BAX60_18295 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAX60_18300 ENOG4105SXS Protein of unknown function (DUF456) BAX60_18315 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) BAX60_18320 ENOG41063Y9 BAX60_18325 ENOG4108U5J '-nucleotidase BAX60_18330 ENOG4105N80 Ferric uptake regulator, Fur family BAX60_18335 ENOG4108JYZ YitT family BAX60_18340 ENOG41069ZM Protein of unknown function (DUF2624) BAX60_18345 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) BAX60_18360 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) BAX60_18365 ENOG4105EGD dinuclear metal center protein, YbgI family BAX60_18380 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAX60_18385 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BAX60_18390 ENOG41082VT Uncharacterized BCR, YaiI/YqxD family COG1671 BAX60_18395 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) BAX60_18405 ENOG4105C38 Glycyl-tRNA synthetase beta subunit BAX60_18410 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BAX60_18415 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) BAX60_18425 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BAX60_18430 ENOG4105KG3 cytidine deaminase BAX60_18435 ENOG4107YR5 Diacylglycerol kinase BAX60_18440 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BAX60_18445 ENOG4105CTJ Metal Dependent Phosphohydrolase BAX60_18455 ENOG4105C9A Phoh family BAX60_18460 ENOG4105EI1 sporulation protein yqfd BAX60_18465 ENOG41068P3 sporulation protein YqfC BAX60_18475 ENOG4105DI5 UPF0365 protein BAX60_18480 ENOG4105F7J membrane-bound serine protease BAX60_18485 ENOG4105KTH gatB Yqey BAX60_18500 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAX60_18505 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BAX60_18510 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BAX60_18520 ENOG4105CFG Acts as a chaperone (By similarity) BAX60_18525 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BAX60_18530 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) BAX60_18535 ENOG4105CSA Coproporphyrinogen iii oxidase BAX60_18540 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) BAX60_18550 ENOG4108ZRV stage ii sporulation protein p BAX60_18555 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) BAX60_18560 ENOG41082YS Binds directly to 16S ribosomal RNA BAX60_18565 ENOG4105TQK DNA polymerase iii, delta' subunit BAX60_18575 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAX60_18580 ENOG4108UK2 deaminase BAX60_18585 ENOG4105KQC Competence protein BAX60_18595 ENOG4108D32 Methyltransferase BAX60_18605 ENOG4108WF2 Metal Dependent Phosphohydrolase BAX60_18610 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) BAX60_18615 ENOG410812S Rna-binding protein BAX60_18620 ENOG4105E2X shikimate dehydrogenase BAX60_18625 ENOG4105CQW ribosome biogenesis GTPase YqeH BAX60_18630 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAX60_18655 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAX60_18660 ENOG41080BT SNARE associated Golgi BAX60_18675 ENOG4105WFK nuclease BAX60_18680 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAX60_18705 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr BAX60_18715 ENOG4105RV9 Transcriptional regulator BAX60_18720 ENOG41082J7 Rhodanese domain protein BAX60_18740 ENOG4108R6W Transcriptional regulator, ARAC family BAX60_18750 ENOG4105EMU Dehydrogenase BAX60_18810 ENOG4105KVH Transcriptional regulator BAX60_18815 ENOG4108DBC nitroreductase BAX60_18820 ENOG41067XF inhibitor BAX60_18830 ENOG41090E6 transcriptional regulator MERR family BAX60_18865 ENOG4105UNS Pfam:DUF419 BAX60_18875 ENOG4108MEK Metal-binding protein YodA BAX60_18880 ENOG410904A RNA polymerase BAX60_18885 ENOG4105CPC Aldo Keto reductase BAX60_18890 ENOG41083Q9 chitosanase BAX60_18895 ENOG4105X5K response regulator receiver protein BAX60_18900 ENOG4108VQT Alpha beta hydrolase fold protein BAX60_18905 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein BAX60_18910 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein BAX60_18920 ENOG4105PGS Spore coat protein BAX60_18925 ENOG4105E2A Dehydrogenase BAX60_18950 ENOG4105VUF Transcriptional regulator BAX60_18965 ENOG4105DQ4 alcohol dehydrogenase BAX60_18970 ENOG4108Z0Z intracellular protease Pfpi family BAX60_18975 ENOG4108HKT sucrose-6-phosphate hydrolase BAX60_18980 ENOG4105F3R pts system mannose fructose sorbose family iid BAX60_18985 ENOG4105ETZ PTS System BAX60_18990 ENOG4108IQ3 PTS system BAX60_18995 ENOG4105YHU PTS system BAX60_19000 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BAX60_19010 ENOG4105C85 amino acid BAX60_19015 ENOG4105N14 lysine exporter protein LysE YggA BAX60_19020 ENOG4108NGU Transcriptional regulator BAX60_19025 ENOG4105JVQ RNA Polymerase BAX60_19030 ENOG4108P49 AntiSigma factor BAX60_19035 ENOG4105EXC Acyl-transferase BAX60_19040 ENOG4105WDR BAX60_19045 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAX60_19050 ENOG41082JN Transcriptional regulator BAX60_19065 ENOG4105TMB Formate nitrite transporter BAX60_19070 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BAX60_19075 ENOG4108JB9 formate dehydrogenase BAX60_19090 ENOG4105C28 cystathionine BAX60_19105 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BAX60_19120 ENOG4107XRG penicillin-binding protein BAX60_19125 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BAX60_19130 ENOG4105DBI uridine monophosphokinase BAX60_19135 ENOG4105CFP Peptidase U32 BAX60_19140 ENOG4105XYU peptidase (U32 family) BAX60_19145 ENOG4108VQJ O-methyltransferase BAX60_19150 ENOG4105HHA aminodeoxychorismate lyase BAX60_19155 ENOG4105VPH UPF0473 protein BAX60_19160 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) BAX60_19165 ENOG4105VBH UPF0297 protein BAX60_19170 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAX60_19175 ENOG4105C02 permease BAX60_19185 ENOG41060CR BAX60_19195 ENOG4105C7H Helicase, RecD TraA family BAX60_19205 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BAX60_19210 ENOG4105C3J Cysteine desulfurase BAX60_19220 ENOG4105D1H recombination factor protein RarA BAX60_19225 ENOG4105CUZ uba thif-type nad fad binding protein BAX60_19235 ENOG4105C9M aspartyl-trna synthetase BAX60_19240 ENOG4105CUT histidyl-tRNA synthetase BAX60_19250 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAX60_19260 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BAX60_19265 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BAX60_19270 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BAX60_19275 ENOG41067VP Protein of unknown function (DUF1049) BAX60_19280 ENOG4105NCW Trka-c domain protein BAX60_19285 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BAX60_19295 ENOG4105CKP Polysaccharide Biosynthesis Protein BAX60_19300 ENOG4108QG2 Membrane BAX60_19305 ENOG4105NAP BAX60_19310 ENOG4105VIE preprotein translocase, subunit YajC BAX60_19315 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) BAX60_19320 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BAX60_19325 ENOG41061AI Protein of unknown function (DUF2905) BAX60_19330 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) BAX60_19335 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) BAX60_19345 ENOG4105IE8 Alpha-ketoglutarate permease BAX60_19350 ENOG4105CK5 oxidoreductase BAX60_19365 ENOG4105BZG amino acid carrier protein BAX60_19370 ENOG4105CDY transcriptional regulatory protein BAX60_19380 ENOG4106678 morphogenetic protein associated with SpoVID BAX60_19385 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BAX60_19390 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BAX60_19395 ENOG4108IYU L-aspartate oxidase BAX60_19410 ENOG4105CQC Prephenate dehydratase BAX60_19415 ENOG41090I5 UPF0735 ACT domain-containing protein BAX60_19420 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BAX60_19430 ENOG4105K46 50S ribosomal protein l27 BAX60_19435 ENOG4105X36 (ribosomal) protein BAX60_19440 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) BAX60_19455 ENOG4107QMS site-determining protein BAX60_19460 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) BAX60_19465 ENOG4105YHC Rod shape-determining protein MreD BAX60_19470 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BAX60_19475 ENOG4105DFF Rod shape-determining protein mreb BAX60_19480 ENOG4105W5Q DNA repair protein (RadC BAX60_19485 ENOG4108Z03 MAF-like protein BAX60_19495 ENOG4106A3R peptidase BAX60_19500 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BAX60_19505 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BAX60_19515 ENOG4106AR7 Spore coat protein BAX60_19520 ENOG41068KH stage VI sporulation protein D BAX60_19525 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BAX60_19530 ENOG4105D52 delta-aminolevulinic acid dehydratase BAX60_19540 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BAX60_19550 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) BAX60_19560 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) BAX60_19565 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BAX60_19570 ENOG4108IUQ atp-dependent protease BAX60_19575 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) BAX60_19580 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BAX60_19590 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BAX60_19595 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BAX60_19600 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAX60_19605 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) BAX60_19610 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAX60_19615 ENOG4108ZP8 Acetolactate synthase small subunit BAX60_19620 ENOG4105C7K acetolactate synthase BAX60_19630 ENOG4105I4A GCN5-related N-acetyltransferase BAX60_19640 ENOG4107KM7 Heat induced stress protein YflT BAX60_19650 ENOG4105M59 Phosphodiesterase, mj0936 family BAX60_19655 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BAX60_19660 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) BAX60_19665 ENOG4108XJQ germination protein BAX60_19670 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BAX60_19675 ENOG41067TZ transcriptional regulator, MarR family BAX60_19680 ENOG4105PFC Transcriptional regulator BAX60_19690 ENOG4105E33 succinate dehydrogenase BAX60_19700 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BAX60_19715 ENOG4105CFH Aspartokinase BAX60_19725 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BAX60_19730 ENOG4105K63 Thioredoxin BAX60_19740 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BAX60_19745 ENOG4105C10 Electron transfer flavoprotein BAX60_19750 ENOG4105BZJ Electron transfer flavoprotein BAX60_19755 ENOG41060WC Enoyl-CoA hydratase BAX60_19760 ENOG4107Z3H Transcriptional regulator, TetR family BAX60_19765 ENOG4105CEY Amp-dependent synthetase and ligase BAX60_19775 ENOG4105C98 muts2 protein BAX60_19780 ENOG4105DCG PHP domain protein BAX60_19795 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BAX60_19805 ENOG4105DQ6 Transposase BAX60_19810 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BAX60_19815 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) BAX60_19825 ENOG4108RWN rrna methyltransferase BAX60_19830 ENOG41067MF small acid-soluble spore protein BAX60_19840 ENOG4105CQB FAD linked oxidase domain protein BAX60_19845 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAX60_19875 ENOG4105K7K Transcriptional regulator BAX60_19880 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BAX60_19885 ENOG4105DRS transport system, permease BAX60_19900 ENOG4108MDK Dehydrogenase BAX60_19910 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BAX60_19915 ENOG4105EF1 ribulokinase BAX60_19925 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase BAX60_19930 ENOG4105CN9 Peptidase m42 family protein BAX60_19940 ENOG410696E Membrane BAX60_19945 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BAX60_19950 ENOG4105VJV 50s ribosomal protein L35 BAX60_19955 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BAX60_19970 ENOG41067MG lrgb family BAX60_19980 ENOG4105DY9 regulatoR BAX60_19985 ENOG4108HRK Histidine kinase BAX60_19990 ENOG4105U0R haloacid dehalogenase-like hydrolase BAX60_19995 ENOG4105C22 threonyL-tRNA synthetase BAX60_20000 ENOG4108TDW sporulation protein YtxC BAX60_20020 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) BAX60_20025 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAX60_20030 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BAX60_20035 ENOG4105KVH Transcriptional regulator BAX60_20040 ENOG4105F27 Major Facilitator BAX60_20045 ENOG4105CV8 reductase BAX60_20050 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BAX60_20060 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BAX60_20065 ENOG4105C2M dna polymerase I BAX60_20070 ENOG4105BZU Histidine kinase BAX60_20075 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAX60_20080 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAX60_20085 ENOG4108HMX isocitrate dehydrogenase (NADP) BAX60_20090 ENOG4105BZN citrate synthase BAX60_20100 ENOG4108REF Sporulation integral membrane protein ytvi BAX60_20105 ENOG4105FS0 cytoplasmic membrane protein BAX60_20110 ENOG4105CA9 Pyruvate kinase BAX60_20115 ENOG4105CTQ phosphohexokinase BAX60_20125 ENOG4108IEY Carboxyl transferase domain BAX60_20130 ENOG4105C6K Malic enzyme BAX60_20135 ENOG4105C0B DNA polymerase III (alpha subunit) BAX60_20140 ENOG4105VV2 BAX60_20150 ENOG4106EVM BAX60_20155 ENOG4105SFS phosphoesterase RecJ domain protein BAX60_20170 ENOG4105E8R UPF0173 metal-dependent hydrolase BAX60_20185 ENOG4105CH7 arginosuccinase BAX60_20190 ENOG4105CDH Citrulline--aspartate ligase BAX60_20195 ENOG4105EPU Molybdenum cofactor synthesis domain protein BAX60_20200 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BAX60_20210 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BAX60_20215 ENOG4105KBJ sporulation protein ytfj BAX60_20225 ENOG4105VK3 rdd domain containing protein BAX60_20230 ENOG4105D07 Signal peptide peptidase, SppA BAX60_20235 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAX60_20240 ENOG4105EFZ amidohydrolase BAX60_20245 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAX60_20280 ENOG4105U5Y Transcriptional regulator BAX60_20290 ENOG4105BZU Histidine kinase BAX60_20300 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BAX60_20310 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAX60_20320 ENOG4105F1V Acetoin utilization protein BAX60_20325 ENOG4105W87 Cbs domain BAX60_20330 ENOG4105DGU Histone deacetylase BAX60_20335 ENOG4105ER2 Ompa motb domain protein BAX60_20340 ENOG4107R0U MotA TolQ exbB proton channel BAX60_20345 ENOG4105ETE Transcriptional regulator (LacI family BAX60_20350 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BAX60_20370 ENOG4105DFU Cell wall formation (By similarity) BAX60_20380 ENOG4108VDD TRNA binding domain protein BAX60_20395 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ BAX60_20410 ENOG4105C6K Malic enzyme BAX60_20415 ENOG4105C8F Beta-lactamase domain protein BAX60_20420 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BAX60_20430 ENOG4108V15 phosphotransferase enzyme family BAX60_20435 ENOG4108IUM Glycogen debranching enzyme BAX60_20450 ENOG4107F58 2'-5' rna ligase BAX60_20455 ENOG4105C6T cysteine synthase BAX60_20460 ENOG4107QSE Dipeptidase BAX60_20465 ENOG4105C7N Xanthine uracil vitamin C permease BAX60_20480 ENOG4105YW5 deoR family transcriptional regulator BAX60_20495 ENOG4105CBX hi0933 family BAX60_20500 ENOG4105C94 Transporter BAX60_20510 ENOG4105MU9 integral membrane protein BAX60_20515 ENOG4105DDC Oxidoreductase domain protein BAX60_20525 ENOG4105F5H Glycosyl Hydrolase Family 88 BAX60_20535 ENOG41075H3 AraC family transcriptional regulator BAX60_20545 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component BAX60_20555 ENOG4106A3M Cytochrome p-450 BAX60_20560 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BAX60_20570 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAX60_20575 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAX60_20580 ENOG4108W8G Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity) BAX60_20590 ENOG4105NTD Inherit from COG: Hydrolase BAX60_20605 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BAX60_20610 ENOG4105I1K ABC transporter BAX60_20620 ENOG41085GJ domain protein BAX60_20625 ENOG4105C8T Leucyl-tRNA synthetase BAX60_20635 ENOG4105BZU Histidine kinase BAX60_20640 ENOG410605W Major Facilitator BAX60_20645 ENOG4106UBQ BAX60_20655 ENOG4105C19 ABC transporter BAX60_20660 ENOG4105EWM Histidine kinase BAX60_20670 ENOG4107R34 abc transporter permease protein BAX60_20675 ENOG4105C19 ABC transporter BAX60_20690 ENOG4105DVE abc transporter atp-binding protein BAX60_20695 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAX60_20710 ENOG4105N5T Radical SAM Protein BAX60_20725 ENOG4105E8V Alpha Beta Hydrolase Fold protein BAX60_20730 ENOG4108Z0R Transferase BAX60_20735 ENOG4105C85 amino acid BAX60_20740 ENOG4105CAQ asparagine synthetase BAX60_20745 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP BAX60_20750 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase BAX60_20765 ENOG4105D2X ABC transporter substrate-binding protein BAX60_20775 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BAX60_20790 ENOG4108RMU ferritin dps family protein BAX60_20805 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) BAX60_20810 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) BAX60_20815 ENOG4108V2W Carbonate dehydratase BAX60_20840 ENOG4105CC5 ABC transporter BAX60_20845 ENOG4105CC5 ABC transporter BAX60_20850 ENOG4105DIK (ABC) transporter BAX60_20855 ENOG4105DSE periplasmic solute binding protein BAX60_20860 ENOG4105DTQ mandelate racemase muconate lactonizing BAX60_20865 ENOG4105CEY Amp-dependent synthetase and ligase BAX60_20870 ENOG4108IPT Naphthoate synthase BAX60_20875 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BAX60_20880 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BAX60_20885 ENOG4105E4F Isochorismate synthase BAX60_20905 ENOG4108IAJ Nad-dependent epimerase dehydratase BAX60_20910 ENOG4107SBE Glycosyl transferase (Group 1 BAX60_20925 ENOG4107SBE Glycosyl transferase (Group 1 BAX60_20930 ENOG4108KS4 Spore coat protein BAX60_20945 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BAX60_20955 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BAX60_21090 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BAX60_21095 ENOG4105VRR gCN5-related N-acetyltransferase BAX60_21100 ENOG4105DZ6 Band 7 protein BAX60_21110 ENOG4106DF1 BAX60_21115 ENOG4108VNY MOSC domain protein BAX60_21120 ENOG4108JB8 alcohol dehydrogenase BAX60_21125 ENOG4105C26 Dehydrogenase BAX60_21130 ENOG4105TRT Transcriptional regulator BAX60_21145 ENOG4105CZN Potassium uptake protein BAX60_21150 ENOG4107I77 yiaA/B two helix domain BAX60_21155 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BAX60_21195 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase