locus-tag	class	description
D3Z17_00015	COG0516	GMP reductase activity
D3Z17_00015	COG0517	IMP dehydrogenase activity
D3Z17_00020	COG1686	Belongs to the peptidase S11 family
D3Z17_00025	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D3Z17_00030	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D3Z17_00035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D3Z17_00045	COG1428	Deoxynucleoside kinase
D3Z17_00050	COG1428	Deoxynucleoside kinase
D3Z17_00055	COG1388	LysM domain
D3Z17_00055	COG3858	chitin binding
D3Z17_00060	COG1335	isochorismatase
D3Z17_00065	COG0590	tRNA wobble adenosine to inosine editing
D3Z17_00075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D3Z17_00080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D3Z17_00085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D3Z17_00110	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D3Z17_00115	COG3853	Toxic anion resistance protein (TelA)
D3Z17_00120	COG1982	Orn Lys Arg decarboxylase major
D3Z17_00125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3Z17_00130	COG3870	Protein conserved in bacteria
D3Z17_00135	COG1728	Protein conserved in bacteria
D3Z17_00140	COG0470	DNA polymerase III
D3Z17_00145	COG1774	PSP1 C-terminal conserved region
D3Z17_00150	COG4467	Involved in initiation control of chromosome replication
D3Z17_00155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D3Z17_00160	COG2827	Endonuclease containing a URI domain
D3Z17_00165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D3Z17_00170	COG2002	toxin-antitoxin pair type II binding
D3Z17_00175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3Z17_00175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3Z17_00180	COG0084	hydrolase, TatD family'
D3Z17_00185	COG3583	domain protein
D3Z17_00185	COG3584	3D domain protein
D3Z17_00190	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D3Z17_00195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D3Z17_00205	COG4466	Protein conserved in bacteria
D3Z17_00215	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D3Z17_00220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3Z17_00225	COG0251	oxidation-reduction process
D3Z17_00230	COG2088	sporulation resulting in formation of a cellular spore
D3Z17_00235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D3Z17_00240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D3Z17_00245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D3Z17_00250	COG0193	aminoacyl-tRNA hydrolase activity
D3Z17_00260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D3Z17_00265	COG2002	toxin-antitoxin pair type II binding
D3Z17_00270	COG2244	polysaccharide biosynthetic process
D3Z17_00275	COG3956	TIGRFAM MazG family protein
D3Z17_00280	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D3Z17_00295	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D3Z17_00300	COG1098	S1 RNA binding domain
D3Z17_00315	COG2208	phosphoserine phosphatase activity
D3Z17_00320	COG2304	oxidoreductase activity
D3Z17_00325	COG0515	serine threonine protein kinase
D3Z17_00330	COG0037	tRNA processing
D3Z17_00340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3Z17_00345	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D3Z17_00350	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D3Z17_00355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3Z17_00360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3Z17_00365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3Z17_00370	COG0512	Glutamine amidotransferase of anthranilate synthase
D3Z17_00375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3Z17_00380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D3Z17_00385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D3Z17_00390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D3Z17_00395	COG1396	sequence-specific DNA binding
D3Z17_00400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3Z17_00405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D3Z17_00415	COG4463	regulation of RNA biosynthetic process
D3Z17_00420	COG3880	PFAM UvrB UvrC protein
D3Z17_00425	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D3Z17_00430	COG0542	response to heat
D3Z17_00435	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D3Z17_00440	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D3Z17_00445	COG4956	integral membrane protein (PIN domain superfamily)
D3Z17_00450	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D3Z17_00455	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D3Z17_00460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D3Z17_00470	COG1045	serine acetyltransferase
D3Z17_00475	COG0215	cysteine-tRNA ligase activity
D3Z17_00480	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D3Z17_00485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3Z17_00490	COG3688	RNA-binding protein containing a PIN domain
D3Z17_00495	COG1595	DNA-templated transcription, initiation
D3Z17_00500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3Z17_00505	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D3Z17_00510	COG0250	Participates in transcription elongation, termination and antitermination
D3Z17_00515	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D3Z17_00520	COG0081	regulation of translation
D3Z17_00525	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D3Z17_00530	COG0222	ribosome binding
D3Z17_00535	COG2813	Specifically methylates the guanine in position
D3Z17_00540	COG0085	RNA polymerase activity
D3Z17_00545	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D3Z17_00550	COG1358	cellular component organization or biogenesis
D3Z17_00555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D3Z17_00560	COG0049	tRNA binding
D3Z17_00565	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D3Z17_00570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D3Z17_00575	COG0596	Alpha beta hydrolase
D3Z17_00580	COG0051	transcription antitermination factor activity, RNA binding
D3Z17_00585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D3Z17_00590	COG0088	Forms part of the polypeptide exit tunnel
D3Z17_00595	COG0089	rRNA binding
D3Z17_00600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D3Z17_00605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D3Z17_00610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D3Z17_00615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D3Z17_00620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D3Z17_00625	COG0255	Belongs to the universal ribosomal protein uL29 family
D3Z17_00630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D3Z17_00635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D3Z17_00645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D3Z17_00655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D3Z17_00660	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D3Z17_00665	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D3Z17_00670	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D3Z17_00675	COG1841	ribosomal large subunit assembly
D3Z17_00680	COG0200	Binds to the 23S rRNA
D3Z17_00685	COG0201	protein transport
D3Z17_00690	COG0563	adenylate kinase activity
D3Z17_00695	COG0024	Methionine aminopeptidase
D3Z17_00700	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D3Z17_00705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D3Z17_00710	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D3Z17_00715	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D3Z17_00720	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D3Z17_00725	COG0202	RNA polymerase activity
D3Z17_00730	COG0203	ribosomal protein L17
D3Z17_00735	COG1122	ATPase activity
D3Z17_00740	COG1122	ATPase activity
D3Z17_00745	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D3Z17_00750	COG0101	tRNA pseudouridine synthase activity
D3Z17_00755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D3Z17_00760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D3Z17_00765	COG2226	methyltransferase
D3Z17_00775	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z17_00780	COG0489	protein tyrosine kinase activity
D3Z17_00790	COG2194	sulfuric ester hydrolase activity
D3Z17_00795	COG0726	polysaccharide deacetylase
D3Z17_00805	COG0659	secondary active sulfate transmembrane transporter activity
D3Z17_00810	COG0385	Bile acid
D3Z17_00815	COG2819	hydrolase of the alpha beta superfamily
D3Z17_00820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z17_00825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z17_00830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z17_00835	COG2207	Transcriptional regulator
D3Z17_00835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z17_00840	COG3876	Protein conserved in bacteria
D3Z17_00845	COG1472	Belongs to the glycosyl hydrolase 3 family
D3Z17_00850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3Z17_00855	COG1263	PTS System
D3Z17_00855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_00860	COG1737	Transcriptional regulator
D3Z17_00865	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D3Z17_00870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z17_00875	COG1683	Conserved Protein
D3Z17_00905	COG1595	DNA-templated transcription, initiation
D3Z17_00910	COG5662	AntiSigma factor
D3Z17_00915	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D3Z17_00920	COG4856	YbbR-like protein
D3Z17_00925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3Z17_00930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D3Z17_00940	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D3Z17_00945	COG2169	Transcriptional regulator
D3Z17_00950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3Z17_00955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3Z17_00960	COG3002	Belongs to the UPF0753 family
D3Z17_00965	COG0288	reversible hydration of carbon dioxide
D3Z17_00975	COG5609	conserved protein (DUF2294)
D3Z17_00980	COG0640	Transcriptional regulator
D3Z17_00985	COG2814	Major facilitator Superfamily
D3Z17_01000	COG0515	serine threonine protein kinase
D3Z17_01015	COG1113	amino acid transport
D3Z17_01030	COG2602	Beta-lactamase
D3Z17_01035	COG2124	cytochrome p450
D3Z17_01045	COG0531	amino acid
D3Z17_01050	COG0584	glycerophosphoryl diester phosphodiesterase
D3Z17_01055	COG2271	Major facilitator Superfamily
D3Z17_01070	COG1846	Transcriptional regulator
D3Z17_01070	COG0456	acetyltransferase
D3Z17_01075	COG2271	Major facilitator Superfamily
D3Z17_01085	COG3409	Peptidoglycan-binding domain 1 protein
D3Z17_01090	COG0697	spore germination
D3Z17_01095	COG2207	Transcriptional regulator
D3Z17_01095	COG1917	Cupin 2, conserved barrel domain protein
D3Z17_01100	COG1397	ADP-ribosylglycohydrolase
D3Z17_01105	COG5444	nuclease activity
D3Z17_01110	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D3Z17_01115	COG3591	Belongs to the peptidase S1B family
D3Z17_01125	COG0596	Alpha beta hydrolase
D3Z17_01130	COG1183	phosphatidylcholine synthase activity
D3Z17_01135	COG0586	Pfam SNARE associated Golgi protein
D3Z17_01140	COG0688	phosphatidylethanolamine metabolic process
D3Z17_01150	COG2312	Erythromycin esterase
D3Z17_01160	COG1301	dicarboxylic acid transport
D3Z17_01165	COG2190	(PTS) system
D3Z17_01165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_01165	COG1263	PTS System
D3Z17_01170	COG0363	glucosamine-6-phosphate deaminase activity
D3Z17_01185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3Z17_01190	COG0833	amino acid
D3Z17_01195	COG2040	homocysteine
D3Z17_01205	COG1115	amino acid carrier protein
D3Z17_01210	COG2066	Belongs to the glutaminase family
D3Z17_01215	COG4191	Histidine kinase
D3Z17_01220	COG0784	Response regulator, receiver
D3Z17_01230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3Z17_01235	COG1012	belongs to the aldehyde dehydrogenase family
D3Z17_01240	COG2271	Major facilitator Superfamily
D3Z17_01245	COG4948	Mandelate Racemase Muconate Lactonizing
D3Z17_01250	COG2186	Transcriptional regulator
D3Z17_01255	COG2721	sulfolactate sulfo-lyase activity
D3Z17_01260	COG3173	Aminoglycoside phosphotransferase
D3Z17_01270	COG0697	spore germination
D3Z17_01275	COG0745	RESPONSE REGULATOR receiver
D3Z17_01280	COG2205	protein histidine kinase activity
D3Z17_01285	COG1131	(ABC) transporter
D3Z17_01300	COG3773	Cell wall hydrolase
D3Z17_01305	COG2304	oxidoreductase activity
D3Z17_01315	COG3540	Alkaline phosphatase
D3Z17_01320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3Z17_01325	COG0805	protein transport
D3Z17_01330	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D3Z17_01335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3Z17_01340	COG0477	Major facilitator Superfamily
D3Z17_01345	COG1309	transcriptional regulator
D3Z17_01350	COG0252	asparaginase activity
D3Z17_01355	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D3Z17_01360	COG1714	RDD family
D3Z17_01365	COG1405	negative regulation of cell septum assembly
D3Z17_01365	COG3012	SEC-C Motif Domain Protein
D3Z17_01370	COG3290	protein histidine kinase activity
D3Z17_01375	COG3279	Response regulator of the LytR AlgR family
D3Z17_01380	COG4555	ABC transporter
D3Z17_01385	COG1668	transmembrane transport
D3Z17_01390	COG0667	Aldo Keto reductase
D3Z17_01400	COG1595	DNA-templated transcription, initiation
D3Z17_01405	COG1595	DNA-templated transcription, initiation
D3Z17_01410	COG1876	peptidase activity
D3Z17_01415	COG0457	Tetratricopeptide repeat
D3Z17_01420	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_01425	COG0366	Alpha amylase catalytic
D3Z17_01430	COG0803	Belongs to the bacterial solute-binding protein 9 family
D3Z17_01435	COG1121	(ABC) transporter
D3Z17_01440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3Z17_01445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z17_01450	COG2310	stress, protein
D3Z17_01455	COG2310	stress, protein
D3Z17_01460	COG2310	stress, protein
D3Z17_01465	COG0861	Integral membrane protein TerC family
D3Z17_01475	COG3853	Toxic anion resistance protein (TelA)
D3Z17_01480	COG0477	Major facilitator Superfamily
D3Z17_01490	COG2814	Major facilitator Superfamily
D3Z17_01495	COG0640	Transcriptional regulator
D3Z17_01500	COG0517	IMP dehydrogenase activity
D3Z17_01500	COG4175	Glycine betaine
D3Z17_01505	COG4176	ABC-type proline glycine betaine transport system permease component
D3Z17_01510	COG2113	Glycine betaine
D3Z17_01515	COG1473	amidohydrolase
D3Z17_01520	COG1288	antiporter activity
D3Z17_01530	COG0366	Alpha amylase catalytic
D3Z17_01535	COG0039	L-malate dehydrogenase activity
D3Z17_01540	COG1620	l-lactate permease
D3Z17_01545	COG2814	Major facilitator Superfamily
D3Z17_01550	COG1846	Transcriptional regulator
D3Z17_01555	COG1280	lysine exporter protein (LysE YggA)
D3Z17_01560	COG3403	YqcI/YcgG family
D3Z17_01565	COG1113	amino acid transport
D3Z17_01570	COG3665	Urea carboxylase-associated protein
D3Z17_01575	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D3Z17_01585	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D3Z17_01590	COG2226	methyltransferase
D3Z17_01595	COG0583	DNA-binding transcription factor activity
D3Z17_01600	COG3458	cephalosporin-C deacetylase activity
D3Z17_01605	COG3541	Predicted nucleotidyltransferase
D3Z17_01610	COG0506	proline dehydrogenase activity
D3Z17_01615	COG1012	belongs to the aldehyde dehydrogenase family
D3Z17_01620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3Z17_01625	COG2508	Transcriptional regulator
D3Z17_01630	COG3689	TIGRFAM TIGR03943 family protein
D3Z17_01635	COG0701	Predicted permease
D3Z17_01640	COG2267	carboxylic ester hydrolase activity
D3Z17_01645	COG0492	ferredoxin-NADP+ reductase activity
D3Z17_01650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3Z17_01650	COG1587	Uroporphyrinogen-III synthase
D3Z17_01655	COG2146	nitrite reductase [NAD(P)H] activity
D3Z17_01660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3Z17_01665	COG0243	molybdopterin cofactor binding
D3Z17_01670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3Z17_01675	COG2223	nitrite transmembrane transporter activity
D3Z17_01680	COG1469	GTP cyclohydrolase I activity
D3Z17_01685	COG1376	ErfK ybiS ycfS ynhG family protein
D3Z17_01695	COG0523	cobalamin synthesis protein
D3Z17_01700	COG0765	amino acid transport
D3Z17_01705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z17_01715	COG1714	RDD family
D3Z17_01725	COG2723	6-phospho-beta-galactosidase activity
D3Z17_01735	COG3209	COG3209 Rhs family protein
D3Z17_01740	COG0840	transmembrane signaling receptor activity
D3Z17_01740	COG3290	protein histidine kinase activity
D3Z17_01745	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D3Z17_01750	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D3Z17_01755	COG1733	regulation of RNA biosynthetic process
D3Z17_01760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z17_01770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z17_01775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z17_01780	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D3Z17_01785	COG2814	Major facilitator Superfamily
D3Z17_01795	COG0697	spore germination
D3Z17_01800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z17_01810	COG2364	Membrane
D3Z17_01815	COG1126	abc transporter atp-binding protein
D3Z17_01820	COG0765	amino acid transport
D3Z17_01825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z17_01830	COG0583	DNA-binding transcription factor activity
D3Z17_01835	COG0163	prenyltransferase activity
D3Z17_01840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D3Z17_01855	COG0596	Alpha beta hydrolase
D3Z17_01860	COG3104	oligopeptide transport
D3Z17_01865	COG5434	Belongs to the glycosyl hydrolase 28 family
D3Z17_01875	COG0697	spore germination
D3Z17_01885	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D3Z17_01890	COG1136	(ABC) transporter
D3Z17_01895	COG0577	efflux transmembrane transporter activity
D3Z17_01900	COG0745	RESPONSE REGULATOR receiver
D3Z17_01905	COG3850	Histidine kinase
D3Z17_01905	COG5002	protein histidine kinase activity
D3Z17_01910	COG0457	Tetratricopeptide repeat
D3Z17_01930	COG0527	aspartate kinase activity
D3Z17_01935	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z17_01940	COG4605	iron ion homeostasis
D3Z17_01945	COG4604	ABC transporter, ATP-binding protein
D3Z17_01950	COG4607	ABC-type enterochelin transport system periplasmic component
D3Z17_01955	COG2814	Major facilitator Superfamily
D3Z17_01960	COG1309	transcriptional regulator
D3Z17_01965	COG0778	Nitroreductase
D3Z17_01970	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D3Z17_01975	COG0640	Transcriptional regulator
D3Z17_01980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z17_01985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D3Z17_01990	COG1012	belongs to the aldehyde dehydrogenase family
D3Z17_01995	COG4975	Glucose uptake
D3Z17_02000	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_02005	COG4549	nuclear export factor GLE1
D3Z17_02010	COG1276	copper resistance
D3Z17_02010	COG2372	response to copper ion
D3Z17_02015	COG1349	DNA-binding transcription factor activity
D3Z17_02025	COG2213	PTS system mannitol-specific
D3Z17_02030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z17_02035	COG0246	Mannitol dehydrogenase
D3Z17_02040	COG0473	3-isopropylmalate dehydrogenase activity
D3Z17_02045	COG0681	Belongs to the peptidase S26 family
D3Z17_02050	COG0412	Dienelactone hydrolase
D3Z17_02055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D3Z17_02065	COG0561	phosphatase activity
D3Z17_02070	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D3Z17_02075	COG1914	H( )-stimulated, divalent metal cation uptake system
D3Z17_02080	COG4336	lyase activity
D3Z17_02085	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D3Z17_02090	COG1984	allophanate hydrolase subunit 2
D3Z17_02095	COG1414	Transcriptional regulator
D3Z17_02100	COG2755	lipolytic protein G-D-S-L family
D3Z17_02110	COG2329	Antibiotic biosynthesis monooxygenase
D3Z17_02115	COG0768	penicillin binding
D3Z17_02120	COG4989	oxidoreductase activity
D3Z17_02125	COG3711	transcriptional antiterminator
D3Z17_02130	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z17_02135	COG2226	methyltransferase
D3Z17_02140	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_02145	COG1917	Cupin 2, conserved barrel domain protein
D3Z17_02150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z17_02155	COG3871	stress protein (general stress protein 26)
D3Z17_02165	COG2814	Major facilitator Superfamily
D3Z17_02170	COG1522	sequence-specific DNA binding
D3Z17_02175	COG0551	DNA topoisomerase type I activity
D3Z17_02175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3Z17_02180	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D3Z17_02185	COG3706	GGDEF domain
D3Z17_02190	COG5298	Protein conserved in bacteria
D3Z17_02195	COG1215	transferase activity, transferring glycosyl groups
D3Z17_02205	COG0531	amino acid
D3Z17_02210	COG0494	nUDIX hydrolase
D3Z17_02215	COG0028	Belongs to the TPP enzyme family
D3Z17_02225	COG1914	H( )-stimulated, divalent metal cation uptake system
D3Z17_02230	COG2261	transglycosylase associated protein
D3Z17_02235	COG4876	unkown
D3Z17_02240	COG2217	Heavy metal translocating P-type atpase
D3Z17_02245	COG3729	General stress protein
D3Z17_02250	COG0662	Cupin 2, conserved barrel domain protein
D3Z17_02255	COG2329	Antibiotic biosynthesis monooxygenase
D3Z17_02260	COG3546	catalase activity
D3Z17_02265	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3Z17_02270	COG3290	protein histidine kinase activity
D3Z17_02275	COG4565	transcriptional regulatory protein
D3Z17_02280	COG1301	dicarboxylic acid transport
D3Z17_02285	COG0628	permease
D3Z17_02290	COG1131	(ABC) transporter
D3Z17_02295	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D3Z17_02305	COG1960	acyl-CoA dehydrogenase activity
D3Z17_02320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3Z17_02325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_02330	COG1181	Belongs to the D-alanine--D-alanine ligase family
D3Z17_02335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D3Z17_02345	COG0513	Belongs to the DEAD box helicase family
D3Z17_02350	COG3402	PFAM membrane-flanked domain
D3Z17_02355	COG3428	Bacterial PH domain
D3Z17_02360	COG0705	Rhomboid family
D3Z17_02365	COG0736	holo-[acyl-carrier-protein] synthase activity
D3Z17_02370	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D3Z17_02375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3Z17_02380	COG0864	Transcriptional regulator
D3Z17_02385	COG2337	Toxic component of a toxin-antitoxin (TA) module
D3Z17_02390	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z17_02395	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z17_02400	COG2172	sigma factor antagonist activity
D3Z17_02405	COG2208	phosphoserine phosphatase activity
D3Z17_02410	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z17_02415	COG2172	sigma factor antagonist activity
D3Z17_02420	COG1191	sigma factor activity
D3Z17_02425	COG2208	phosphoserine phosphatase activity
D3Z17_02430	COG2183	response to ionizing radiation
D3Z17_02440	COG3091	SprT-like family
D3Z17_02535	COG1476	TRANSCRIPTIONal
D3Z17_02545	COG3239	Fatty acid desaturase
D3Z17_02550	COG1278	Cold shock
D3Z17_02555	COG1329	Transcriptional regulator
D3Z17_02565	COG0697	spore germination
D3Z17_02570	COG1917	Cupin 2, conserved barrel domain protein
D3Z17_02570	COG2207	Transcriptional regulator
D3Z17_02575	COG0697	spore germination
D3Z17_02580	COG2207	Transcriptional regulator
D3Z17_02580	COG3708	Transcriptional regulator
D3Z17_02585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z17_02590	COG0477	Major facilitator Superfamily
D3Z17_02600	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D3Z17_02620	COG1309	transcriptional regulator
D3Z17_02625	COG0697	spore germination
D3Z17_02630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z17_02635	COG2030	dehydratase
D3Z17_02640	COG3545	Serine hydrolase
D3Z17_02645	COG1733	regulation of RNA biosynthetic process
D3Z17_02650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z17_02655	COG1733	regulation of RNA biosynthetic process
D3Z17_02660	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3Z17_02665	COG2814	Major facilitator Superfamily
D3Z17_02670	COG1309	transcriptional regulator
D3Z17_02680	COG0640	Transcriptional regulator
D3Z17_02685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3Z17_02695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z17_02700	COG0697	spore germination
D3Z17_02705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z17_02710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3Z17_02715	COG0640	Transcriptional regulator
D3Z17_02720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3Z17_02735	COG4585	Histidine kinase
D3Z17_02740	COG2197	response regulator
D3Z17_02745	COG2409	Drug exporters of the RND superfamily
D3Z17_02750	COG0596	Alpha beta hydrolase
D3Z17_02755	COG1811	Na channel or pump
D3Z17_02760	COG4978	Transcriptional regulator
D3Z17_02760	COG0789	Transcriptional regulator
D3Z17_02765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3Z17_02770	COG0778	Nitroreductase
D3Z17_02775	COG0346	lactoylglutathione lyase activity
D3Z17_02780	COG2259	Doxx family
D3Z17_02785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_02805	COG2323	membrane
D3Z17_02810	COG2323	membrane
D3Z17_02815	COG0071	Belongs to the small heat shock protein (HSP20) family
D3Z17_02830	COG1309	transcriptional regulator
D3Z17_02840	COG0456	acetyltransferase
D3Z17_02850	COG1113	amino acid transport
D3Z17_02855	COG2318	DinB family
D3Z17_02860	COG1846	Transcriptional regulator
D3Z17_02865	COG1033	growth of symbiont in host cell
D3Z17_02865	COG2409	Drug exporters of the RND superfamily
D3Z17_02870	COG0778	Nitroreductase
D3Z17_02875	COG1846	Transcriptional regulator
D3Z17_02880	COG2814	Major facilitator Superfamily
D3Z17_02885	COG0730	response to heat
D3Z17_02890	COG1802	Transcriptional regulator
D3Z17_02895	COG3858	chitin binding
D3Z17_02895	COG1388	LysM domain
D3Z17_02900	COG1819	glycosyl
D3Z17_02910	COG1785	Belongs to the alkaline phosphatase family
D3Z17_02915	COG5646	InterPro IPR014922
D3Z17_02925	COG0454	-acetyltransferase
D3Z17_02930	COG1078	dGTPase activity
D3Z17_02935	COG1388	LysM domain
D3Z17_02940	COG2814	Major facilitator Superfamily
D3Z17_02945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3Z17_02950	COG1447	Phosphotransferase system cellobiose-specific component IIA
D3Z17_02955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3Z17_02960	COG2723	6-phospho-beta-galactosidase activity
D3Z17_02965	COG2188	Transcriptional regulator
D3Z17_02970	COG1940	carbohydrate kinase activity
D3Z17_02975	COG1482	cell wall glycoprotein biosynthetic process
D3Z17_02980	COG4124	Belongs to the glycosyl hydrolase 26 family
D3Z17_03015	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D3Z17_03020	COG0802	atpase or kinase
D3Z17_03025	COG1214	PFAM Peptidase M22, glycoprotease
D3Z17_03030	COG0456	acetyltransferase
D3Z17_03035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D3Z17_03040	COG0488	(ABC) transporter
D3Z17_03045	COG0315	cyclic pyranopterin monophosphate synthase activity
D3Z17_03050	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D3Z17_03055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3Z17_03060	COG0805	protein transport
D3Z17_03070	COG1266	CAAX protease self-immunity
D3Z17_03075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D3Z17_03080	COG0459	protein refolding
D3Z17_03090	COG1073	alpha beta
D3Z17_03095	COG0457	Tetratricopeptide repeat
D3Z17_03100	COG1063	alcohol dehydrogenase
D3Z17_03105	COG2211	Major facilitator Superfamily
D3Z17_03110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3Z17_03115	COG1842	Phage shock protein A
D3Z17_03120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D3Z17_03125	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D3Z17_03130	COG4260	virion core protein, lumpy skin disease virus
D3Z17_03140	COG2814	Major facilitator Superfamily
D3Z17_03145	COG1063	alcohol dehydrogenase
D3Z17_03150	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D3Z17_03155	COG0823	Involved in the tonB-independent uptake of proteins
D3Z17_03170	COG2267	carboxylic ester hydrolase activity
D3Z17_03180	COG2132	Multicopper oxidase
D3Z17_03185	COG1113	amino acid transport
D3Z17_03195	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3Z17_03200	COG0714	Associated with various cellular activities
D3Z17_03205	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D3Z17_03210	COG1305	Transglutaminase-like
D3Z17_03215	COG0519	Catalyzes the synthesis of GMP from XMP
D3Z17_03215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D3Z17_03220	COG2252	PERMEase
D3Z17_03225	COG3064	Membrane
D3Z17_03235	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D3Z17_03245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D3Z17_03250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D3Z17_03255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D3Z17_03260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D3Z17_03265	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3Z17_03270	COG0047	phosphoribosylformylglycinamidine synthase activity
D3Z17_03275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3Z17_03280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D3Z17_03285	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D3Z17_03290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D3Z17_03295	COG0138	bifunctional purine biosynthesis protein purh
D3Z17_03300	COG0151	Belongs to the GarS family
D3Z17_03305	COG1522	sequence-specific DNA binding
D3Z17_03310	COG0531	amino acid
D3Z17_03320	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D3Z17_03325	COG1470	cell adhesion involved in biofilm formation
D3Z17_03330	COG4496	protein, YerC YecD
D3Z17_03335	COG0069	glutamate synthase activity
D3Z17_03340	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D3Z17_03345	COG0210	DNA helicase
D3Z17_03350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D3Z17_03355	COG4851	CamS sex pheromone cAM373 precursor
D3Z17_03360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3Z17_03365	COG1285	pathogenesis
D3Z17_03370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3Z17_03375	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D3Z17_03380	COG0154	amidase activity
D3Z17_03385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D3Z17_03390	COG1309	transcriptional regulator
D3Z17_03395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3Z17_03400	COG1597	lipid kinase activity
D3Z17_03405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3Z17_03430	COG5444	nuclease activity
D3Z17_03450	COG0457	Tetratricopeptide repeat
D3Z17_03460	COG0217	transcriptional regulatory protein
D3Z17_03470	COG1309	transcriptional regulator
D3Z17_03475	COG3631	Ketosteroid isomerase-related protein
D3Z17_03480	COG0702	epimerase
D3Z17_03495	COG3546	catalase activity
D3Z17_03500	COG0454	-acetyltransferase
D3Z17_03510	COG5578	integral membrane protein
D3Z17_03515	COG2972	Histidine kinase
D3Z17_03520	COG4753	response regulator
D3Z17_03520	COG2207	Transcriptional regulator
D3Z17_03525	COG1653	transport
D3Z17_03530	COG1175	transmembrane transport
D3Z17_03535	COG0395	ABC-type sugar transport system, permease component
D3Z17_03540	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D3Z17_03550	COG2755	lipolytic protein G-D-S-L family
D3Z17_03560	COG5578	integral membrane protein
D3Z17_03565	COG3401	FG-GAP repeat protein
D3Z17_03570	COG3401	FG-GAP repeat protein
D3Z17_03575	COG2755	lipolytic protein G-D-S-L family
D3Z17_03580	COG1874	Beta-galactosidase
D3Z17_03590	COG1653	transport
D3Z17_03595	COG4209	transmembrane transport
D3Z17_03600	COG0395	ABC-type sugar transport system, permease component
D3Z17_03605	COG1486	melibiose metabolic process
D3Z17_03610	COG2323	membrane
D3Z17_03615	COG2329	Antibiotic biosynthesis monooxygenase
D3Z17_03620	COG0346	lactoylglutathione lyase activity
D3Z17_03635	COG5583	Uncharacterized small protein (DUF2292)
D3Z17_03640	COG0670	Belongs to the BI1 family
D3Z17_03645	COG0697	spore germination
D3Z17_03650	COG1846	Transcriptional regulator
D3Z17_03655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3Z17_03670	COG2124	cytochrome p450
D3Z17_03670	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3Z17_03675	COG1368	sulfuric ester hydrolase activity
D3Z17_03680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D3Z17_03685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3Z17_03690	COG1442	glycosyl transferase family 8
D3Z17_03695	COG1216	Glycosyl transferase, family 2
D3Z17_03700	COG1442	glycosyl transferase family 8
D3Z17_03705	COG2223	nitrite transmembrane transporter activity
D3Z17_03710	COG1011	Hydrolase
D3Z17_03715	COG0531	amino acid
D3Z17_03720	COG1012	belongs to the aldehyde dehydrogenase family
D3Z17_03725	COG0840	transmembrane signaling receptor activity
D3Z17_03730	COG0488	(ABC) transporter
D3Z17_03740	COG0789	Transcriptional regulator
D3Z17_03745	COG2814	Major facilitator Superfamily
D3Z17_03760	COG0488	(ABC) transporter
D3Z17_03765	COG0513	Belongs to the DEAD box helicase family
D3Z17_03770	COG0456	acetyltransferase
D3Z17_03775	COG2130	NADP-dependent
D3Z17_03785	COG2211	Major facilitator Superfamily
D3Z17_03790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D3Z17_03795	COG1120	ATPase activity
D3Z17_03800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z17_03805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z17_03810	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D3Z17_03830	COG3866	Pectate lyase
D3Z17_03835	COG0471	metal ion transport
D3Z17_03840	COG3290	protein histidine kinase activity
D3Z17_03845	COG4565	transcriptional regulatory protein
D3Z17_03850	COG3181	Tripartite tricarboxylate transporter family receptor
D3Z17_03855	COG2851	Citrate transporter
D3Z17_03860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z17_03865	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D3Z17_03870	COG1254	Belongs to the acylphosphatase family
D3Z17_03875	COG2258	MOSC domain
D3Z17_03895	COG0024	Methionine aminopeptidase
D3Z17_03900	COG1263	PTS System
D3Z17_03900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_03905	COG1368	sulfuric ester hydrolase activity
D3Z17_03920	COG1115	amino acid carrier protein
D3Z17_03925	COG0531	amino acid
D3Z17_03940	COG0697	spore germination
D3Z17_03945	COG1263	PTS System
D3Z17_03945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_03950	COG0366	Alpha amylase catalytic
D3Z17_03955	COG2188	Transcriptional regulator
D3Z17_03960	COG0778	Nitroreductase
D3Z17_03965	COG0737	Belongs to the 5'-nucleotidase family
D3Z17_03970	COG0693	protein deglycase activity
D3Z17_03975	COG2814	Major facilitator Superfamily
D3Z17_03980	COG4840	Belongs to the UPF0435 family
D3Z17_03985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3Z17_03990	COG4980	gas vesicle protein
D3Z17_03995	COG1295	ribonuclease BN
D3Z17_04000	COG0477	Major facilitator Superfamily
D3Z17_04005	COG0387	Pfam Sodium calcium exchanger
D3Z17_04015	COG0668	transmembrane transport
D3Z17_04020	COG0535	radical SAM domain protein
D3Z17_04030	COG0726	polysaccharide deacetylase
D3Z17_04035	COG2084	Dehydrogenase
D3Z17_04040	COG0598	Magnesium transport protein CorA
D3Z17_04045	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D3Z17_04050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3Z17_04060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3Z17_04065	COG4637	Psort location Cytoplasmic, score
D3Z17_04070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3Z17_04075	COG0022	dehydrogenase e1 component
D3Z17_04080	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3Z17_04085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3Z17_04090	COG3284	Transcriptional regulator
D3Z17_04100	COG1742	UPF0060 membrane protein
D3Z17_04125	COG4842	Belongs to the WXG100 family
D3Z17_04130	COG1486	melibiose metabolic process
D3Z17_04135	COG1737	Transcriptional regulator
D3Z17_04140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_04140	COG1263	PTS System
D3Z17_04145	COG5434	Belongs to the glycosyl hydrolase 28 family
D3Z17_04150	COG1132	(ABC) transporter
D3Z17_04155	COG1132	(ABC) transporter
D3Z17_04160	COG2259	Doxx family
D3Z17_04165	COG2514	catechol 2,3-dioxygenase activity
D3Z17_04170	COG4585	Histidine kinase
D3Z17_04175	COG2197	response regulator
D3Z17_04180	COG1131	(ABC) transporter
D3Z17_04185	COG1511	domain protein
D3Z17_04185	COG0842	Transport permease protein
D3Z17_04190	COG0842	Transport permease protein
D3Z17_04195	COG1695	Transcriptional regulator
D3Z17_04200	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D3Z17_04205	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D3Z17_04210	COG2318	DinB family
D3Z17_04215	COG2814	Major facilitator Superfamily
D3Z17_04220	COG1846	Transcriptional regulator
D3Z17_04225	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D3Z17_04225	COG0392	lysyltransferase activity
D3Z17_04230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z17_04235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z17_04240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z17_04245	COG0384	phenazine biosynthesis protein PhzF
D3Z17_04250	COG0778	Nitroreductase
D3Z17_04265	COG1090	epimerase
D3Z17_04270	COG2137	regulation of response to DNA damage stimulus
D3Z17_04280	COG2814	Major facilitator Superfamily
D3Z17_04295	COG3103	Sh3 type 3 domain protein
D3Z17_04300	COG5658	integral membrane protein
D3Z17_04305	COG0596	Alpha beta hydrolase
D3Z17_04310	COG0463	Glycosyl transferase, family 2
D3Z17_04315	COG4485	Bacterial membrane protein, YfhO
D3Z17_04320	COG1988	membrane-bound metal-dependent
D3Z17_04325	COG1194	a g-specific adenine glycosylase
D3Z17_04335	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_04350	COG3557	Belongs to the UPF0374 family
D3Z17_04355	COG1132	(ABC) transporter
D3Z17_04360	COG4129	membrane
D3Z17_04365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D3Z17_04370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3Z17_04375	COG0735	belongs to the Fur family
D3Z17_04475	COG4326	sporulation control protein
D3Z17_04485	COG5577	PFAM Coat F domain
D3Z17_04495	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D3Z17_04510	COG0753	catalase activity
D3Z17_04515	COG1116	anion transmembrane transporter activity
D3Z17_04520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3Z17_04525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3Z17_04530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z17_04540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D3Z17_04550	COG1476	TRANSCRIPTIONal
D3Z17_04560	COG3382	B3 4 domain protein
D3Z17_04565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D3Z17_04575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D3Z17_04580	COG0789	Transcriptional regulator
D3Z17_04585	COG1664	Polymer-forming cytoskeletal
D3Z17_04590	COG1664	Polymer-forming cytoskeletal
D3Z17_04595	COG2766	serine protein kinase
D3Z17_04600	COG2718	Belongs to the UPF0229 family
D3Z17_04605	COG1846	Transcriptional regulator
D3Z17_04610	COG1566	PFAM secretion protein HlyD family protein
D3Z17_04615	COG2814	Major facilitator Superfamily
D3Z17_04620	COG0655	NAD(P)H dehydrogenase (quinone) activity
D3Z17_04640	COG1725	Transcriptional regulator
D3Z17_04645	COG1131	(ABC) transporter
D3Z17_04650	COG1131	(ABC) transporter
D3Z17_04655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D3Z17_04660	COG1278	Cold shock
D3Z17_04670	COG1464	Belongs to the NlpA lipoprotein family
D3Z17_04675	COG3706	GGDEF domain
D3Z17_04680	COG1823	symporter activity
D3Z17_04710	COG5577	PFAM Coat F domain
D3Z17_04715	COG0737	Belongs to the 5'-nucleotidase family
D3Z17_04715	COG1525	nuclease
D3Z17_04715	COG4085	toxin activity
D3Z17_04720	COG3764	Sortase (surface protein transpeptidase)
D3Z17_04725	COG0564	pseudouridine synthase activity
D3Z17_04735	COG0517	IMP dehydrogenase activity
D3Z17_04740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3Z17_04745	COG3153	acetyltransferase
D3Z17_04745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3Z17_04755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3Z17_04760	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D3Z17_04765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D3Z17_04770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D3Z17_04775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D3Z17_04780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3Z17_04785	COG2203	Gaf domain
D3Z17_04785	COG4585	Histidine kinase
D3Z17_04790	COG2197	response regulator
D3Z17_04795	COG0431	NADPH-dependent FMN reductase
D3Z17_04810	COG1388	LysM domain
D3Z17_04810	COG0791	NLP P60 protein
D3Z17_04815	COG1959	2 iron, 2 sulfur cluster binding
D3Z17_04820	COG0668	transmembrane transport
D3Z17_04825	COG2719	SpoVR family
D3Z17_04830	COG1785	Belongs to the alkaline phosphatase family
D3Z17_04835	COG0791	NLP P60 protein
D3Z17_04835	COG1388	LysM domain
D3Z17_04840	COG0583	DNA-binding transcription factor activity
D3Z17_04845	COG0372	Belongs to the citrate synthase family
D3Z17_04850	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_04855	COG0531	amino acid
D3Z17_04860	COG0733	neurotransmitter:sodium symporter activity
D3Z17_04865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z17_04870	COG0456	acetyltransferase
D3Z17_04885	COG1595	DNA-templated transcription, initiation
D3Z17_04890	COG0667	Aldo Keto reductase
D3Z17_04895	COG0204	Acyl-transferase
D3Z17_04900	COG1253	flavin adenine dinucleotide binding
D3Z17_04905	COG0789	Transcriptional regulator
D3Z17_04910	COG0436	Aminotransferase
D3Z17_04915	COG1253	flavin adenine dinucleotide binding
D3Z17_04920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3Z17_04925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3Z17_04930	COG0584	glycerophosphoryl diester phosphodiesterase
D3Z17_04940	COG0668	transmembrane transport
D3Z17_04945	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D3Z17_04950	COG0726	polysaccharide deacetylase
D3Z17_04955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3Z17_04960	COG1757	Na H antiporter
D3Z17_04965	COG0589	response to stress
D3Z17_04975	COG1132	(ABC) transporter
D3Z17_04980	COG1132	(ABC) transporter
D3Z17_04985	COG0702	epimerase
D3Z17_05005	COG0189	ligase activity
D3Z17_05010	COG0189	ligase activity
D3Z17_05015	COG4399	Belongs to the UPF0754 family
D3Z17_05020	COG3679	Belongs to the UPF0342 family
D3Z17_05025	COG4335	DNA alkylation repair
D3Z17_05030	COG0561	phosphatase activity
D3Z17_05035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3Z17_05040	COG0475	glutathione-regulated potassium exporter activity
D3Z17_05045	COG0490	domain, Protein
D3Z17_05055	COG1024	Enoyl-CoA hydratase
D3Z17_05065	COG4152	abc transporter atp-binding protein
D3Z17_05070	COG1668	transmembrane transport
D3Z17_05075	COG0420	3'-5' exonuclease activity
D3Z17_05080	COG4717	serine-type aminopeptidase activity
D3Z17_05085	COG3481	metal-dependent phosphohydrolase, HD sub domain
D3Z17_05095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3Z17_05125	COG1846	Transcriptional regulator
D3Z17_05130	COG4980	gas vesicle protein
D3Z17_05145	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D3Z17_05150	COG0537	adenosine 5'-monophosphoramidase activity
D3Z17_05155	COG1131	(ABC) transporter
D3Z17_05160	COG4473	ABC transporter
D3Z17_05170	COG1473	amidohydrolase
D3Z17_05175	COG3069	C4-dicarboxylate transmembrane transporter activity
D3Z17_05185	COG2329	Antibiotic biosynthesis monooxygenase
D3Z17_05190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3Z17_05195	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D3Z17_05210	COG1309	transcriptional regulator
D3Z17_05215	COG1511	domain protein
D3Z17_05220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3Z17_05225	COG4377	Putative membrane peptidase family (DUF2324)
D3Z17_05235	COG1363	Peptidase, m42
D3Z17_05240	COG4405	Protein conserved in bacteria
D3Z17_05245	COG1301	dicarboxylic acid transport
D3Z17_05255	COG1234	tRNA 3'-trailer cleavage
D3Z17_05260	COG0095	Lipoate-protein ligase
D3Z17_05265	COG0702	epimerase
D3Z17_05270	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z17_05280	COG0501	Belongs to the peptidase M48B family
D3Z17_05290	COG0456	acetyltransferase
D3Z17_05295	COG0604	alcohol dehydrogenase
D3Z17_05300	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D3Z17_05305	COG0406	alpha-ribazole phosphatase activity
D3Z17_05310	COG0183	Belongs to the thiolase family
D3Z17_05315	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z17_05320	COG1268	BioY protein
D3Z17_05325	COG0840	transmembrane signaling receptor activity
D3Z17_05330	COG0723	plastoquinol--plastocyanin reductase activity
D3Z17_05330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3Z17_05335	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_05345	COG4903	ComK protein
D3Z17_05350	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_05360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3Z17_05375	COG0398	Pfam SNARE associated Golgi protein
D3Z17_05380	COG0681	Belongs to the peptidase S26 family
D3Z17_05385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3Z17_05390	COG1846	Transcriptional regulator
D3Z17_05405	COG0738	Major facilitator superfamily
D3Z17_05410	COG0673	inositol 2-dehydrogenase activity
D3Z17_05415	COG0561	phosphatase activity
D3Z17_05420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3Z17_05425	COG1609	Transcriptional regulator
D3Z17_05430	COG3180	Ammonia monooxygenase
D3Z17_05435	COG0477	Major facilitator Superfamily
D3Z17_05435	COG2814	Major facilitator Superfamily
D3Z17_05440	COG4533	DNA binding
D3Z17_05450	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D3Z17_05455	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D3Z17_05460	COG1074	ATP-dependent DNA helicase activity
D3Z17_05465	COG0420	3'-5' exonuclease activity
D3Z17_05470	COG0419	ATPase involved in DNA repair
D3Z17_05475	COG1403	HNH endonuclease
D3Z17_05515	COG5337	Spore coat protein CotH
D3Z17_05520	COG0179	Fumarylacetoacetate (FAA) hydrolase
D3Z17_05530	COG1404	Belongs to the peptidase S8 family
D3Z17_05540	COG0367	asparagine synthase
D3Z17_05545	COG2318	DinB family
D3Z17_05550	COG1562	ergosterol biosynthetic process
D3Z17_05555	COG0534	Mate efflux family protein
D3Z17_05560	COG1917	Cupin 2, conserved barrel domain protein
D3Z17_05560	COG2207	Transcriptional regulator
D3Z17_05565	COG1609	Transcriptional regulator
D3Z17_05570	COG0673	inositol 2-dehydrogenase activity
D3Z17_05575	COG2318	DinB family
D3Z17_05580	COG1279	arginine transmembrane transporter activity
D3Z17_05585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z17_05590	COG1357	PFAM Pentapeptide repeats (8 copies)
D3Z17_05595	COG2267	carboxylic ester hydrolase activity
D3Z17_05600	COG0529	Catalyzes the synthesis of activated sulfate
D3Z17_05605	COG2046	Belongs to the sulfate adenylyltransferase family
D3Z17_05610	COG0175	sulfate reduction
D3Z17_05615	COG2045	Belongs to the ComB family
D3Z17_05620	COG1809	phosphosulfolactate synthase activity
D3Z17_05625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z17_05630	COG4948	Mandelate Racemase Muconate Lactonizing
D3Z17_05635	COG2814	Major facilitator Superfamily
D3Z17_05640	COG0454	-acetyltransferase
D3Z17_05645	COG2153	protein acetylation
D3Z17_05650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D3Z17_05650	COG0646	methionine synthase
D3Z17_05655	COG1666	GTP binding
D3Z17_05660	COG2996	Protein conserved in bacteria
D3Z17_05680	COG1695	Transcriptional regulator
D3Z17_05695	COG3227	Zinc metalloprotease (Elastase)
D3Z17_05700	COG1307	EDD domain protein, DegV family
D3Z17_05705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z17_05720	COG0561	phosphatase activity
D3Z17_05725	COG1073	alpha beta
D3Z17_05730	COG2151	metal-sulfur cluster biosynthetic enzyme
D3Z17_05740	COG0277	FAD linked oxidase domain protein
D3Z17_05745	COG2271	Major facilitator Superfamily
D3Z17_05750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D3Z17_05765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3Z17_05770	COG0505	Belongs to the CarA family
D3Z17_05775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3Z17_05780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D3Z17_05795	COG2267	carboxylic ester hydrolase activity
D3Z17_05805	COG1744	ABC transporter substrate-binding protein PnrA-like
D3Z17_05820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3Z17_05825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3Z17_05830	COG5504	Zn-dependent protease
D3Z17_05835	COG0444	Belongs to the ABC transporter superfamily
D3Z17_05840	COG4608	Belongs to the ABC transporter superfamily
D3Z17_05850	COG0601	transmembrane transport
D3Z17_05855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3Z17_05865	COG0180	Tryptophanyl-tRNA synthetase
D3Z17_05870	COG4166	transmembrane transport
D3Z17_05875	COG0601	transmembrane transport
D3Z17_05880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3Z17_05885	COG0444	Belongs to the ABC transporter superfamily
D3Z17_05890	COG4608	Belongs to the ABC transporter superfamily
D3Z17_05895	COG2814	Major facilitator Superfamily
D3Z17_05905	COG1393	Belongs to the ArsC family
D3Z17_05910	COG0861	Integral membrane protein TerC family
D3Z17_05915	COG4862	establishment of competence for transformation
D3Z17_05920	COG4469	Competence protein
D3Z17_05925	COG1164	Oligoendopeptidase f
D3Z17_05945	COG2346	COG2346, Truncated hemoglobins
D3Z17_05950	COG0741	lytic transglycosylase activity
D3Z17_05955	COG4116	CYTH
D3Z17_05965	COG2357	RelA SpoT domain protein
D3Z17_05970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D3Z17_05975	COG0564	pseudouridine synthase activity
D3Z17_05980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D3Z17_05985	COG0569	domain protein
D3Z17_05985	COG0475	glutathione-regulated potassium exporter activity
D3Z17_05990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D3Z17_05995	COG0352	thiamine-phosphate diphosphorylase activity
D3Z17_06000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3Z17_06005	COG2104	thiamine diphosphate biosynthetic process
D3Z17_06010	COG2022	thiamine diphosphate biosynthetic process
D3Z17_06015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3Z17_06020	COG0351	phosphomethylpyrimidine kinase
D3Z17_06025	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D3Z17_06080	COG0210	DNA helicase
D3Z17_06090	COG2153	protein acetylation
D3Z17_06095	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D3Z17_06100	COG2382	esterase
D3Z17_06105	COG0626	cystathionine gamma-synthase activity
D3Z17_06110	COG0626	cystathionine gamma-synthase activity
D3Z17_06115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z17_06120	COG5505	Protein of unknown function (DUF819)
D3Z17_06155	COG5444	nuclease activity
D3Z17_06180	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D3Z17_06185	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_06195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z17_06195	COG3711	transcriptional antiterminator
D3Z17_06200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z17_06200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3Z17_06200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3Z17_06205	COG1482	cell wall glycoprotein biosynthetic process
D3Z17_06215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z17_06225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D3Z17_06245	COG0109	protoheme IX farnesyltransferase activity
D3Z17_06255	COG0726	polysaccharide deacetylase
D3Z17_06270	COG5504	Zn-dependent protease
D3Z17_06275	COG2205	protein histidine kinase activity
D3Z17_06290	COG2427	Protein of unknown function (DUF1641)
D3Z17_06300	COG1051	belongs to the nudix hydrolase family
D3Z17_06310	COG2124	cytochrome p450
D3Z17_06315	COG1819	glycosyl
D3Z17_06325	COG1587	Uroporphyrinogen-III synthase
D3Z17_06330	COG0390	transport system, permease component
D3Z17_06335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3Z17_06340	COG0697	spore germination
D3Z17_06345	COG4297	protein containing double-stranded beta helix domain
D3Z17_06355	COG1252	NADH dehydrogenase
D3Z17_06360	COG1904	glucuronate isomerase
D3Z17_06365	COG2211	Major facilitator Superfamily
D3Z17_06370	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D3Z17_06375	COG1063	alcohol dehydrogenase
D3Z17_06380	COG1312	Catalyzes the dehydration of D-mannonate
D3Z17_06385	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_06390	COG2271	Major facilitator Superfamily
D3Z17_06395	COG1609	Transcriptional regulator
D3Z17_06400	COG0246	Mannitol dehydrogenase
D3Z17_06405	COG2721	sulfolactate sulfo-lyase activity
D3Z17_06410	COG0730	response to heat
D3Z17_06415	COG2318	DinB family
D3Z17_06420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3Z17_06425	COG0457	Tetratricopeptide repeat
D3Z17_06435	COG2350	Protein conserved in bacteria
D3Z17_06440	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3Z17_06440	COG3409	Peptidoglycan-binding domain 1 protein
D3Z17_06440	COG1388	LysM domain
D3Z17_06450	COG4195	phage-related replication protein
D3Z17_06455	COG3546	catalase activity
D3Z17_06460	COG2856	Zn peptidase
D3Z17_06465	COG1396	sequence-specific DNA binding
D3Z17_06475	COG1522	sequence-specific DNA binding
D3Z17_06480	COG1484	DNA-dependent DNA replication
D3Z17_06500	COG1595	DNA-templated transcription, initiation
D3Z17_06505	COG3728	DNA packaging
D3Z17_06505	COG5484	DNA packaging
D3Z17_06510	COG1783	phage Terminase large subunit
D3Z17_06515	COG5518	Phage portal protein
D3Z17_06520	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D3Z17_06525	COG4653	Phage capsid family
D3Z17_06575	COG5412	phage tail tape measure protein
D3Z17_06575	COG3953	SLT domain
D3Z17_06580	COG1652	LysM domain
D3Z17_06585	COG4193	domain, Protein
D3Z17_06595	COG3628	GPW Gp25 family protein
D3Z17_06600	COG3299	homolog of phage Mu protein gp47
D3Z17_06605	COG3778	Protein conserved in bacteria
D3Z17_06645	COG3409	Peptidoglycan-binding domain 1 protein
D3Z17_06645	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3Z17_06660	COG0306	phosphate transporter
D3Z17_06665	COG1392	Phosphate transport regulator
D3Z17_06670	COG0531	amino acid
D3Z17_06675	COG0346	lactoylglutathione lyase activity
D3Z17_06680	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D3Z17_06685	COG0463	Glycosyl transferase, family 2
D3Z17_06690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3Z17_06695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3Z17_06700	COG2362	D-Aminopeptidase
D3Z17_06705	COG0601	transmembrane transport
D3Z17_06710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3Z17_06715	COG0444	Belongs to the ABC transporter superfamily
D3Z17_06720	COG4166	transmembrane transport
D3Z17_06725	COG1619	proteins homologs of microcin C7 resistance protein MccF
D3Z17_06730	COG4948	Mandelate Racemase Muconate Lactonizing
D3Z17_06735	COG0791	NLP P60 protein
D3Z17_06740	COG4608	Belongs to the ABC transporter superfamily
D3Z17_06745	COG2706	6-phosphogluconolactonase activity
D3Z17_06750	COG1834	amidinotransferase
D3Z17_06755	COG1607	acyl-coa hydrolase
D3Z17_06760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3Z17_06760	COG1017	nitric oxide dioxygenase activity
D3Z17_06770	COG2323	membrane
D3Z17_06775	COG2318	DinB family
D3Z17_06780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z17_06785	COG2076	Multidrug Resistance protein
D3Z17_06790	COG2076	Multidrug Resistance protein
D3Z17_06795	COG0788	formyltetrahydrofolate deformylase activity
D3Z17_06800	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D3Z17_06805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D3Z17_06810	COG1764	response to oxidative stress
D3Z17_06815	COG1846	Transcriptional regulator
D3Z17_06820	COG1764	response to oxidative stress
D3Z17_06830	COG0590	tRNA wobble adenosine to inosine editing
D3Z17_06835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D3Z17_06840	COG1404	Belongs to the peptidase S8 family
D3Z17_06845	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z17_06850	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D3Z17_06855	COG1122	ATPase activity
D3Z17_06860	COG4721	ABC-type cobalt transport system, permease component
D3Z17_06870	COG0745	RESPONSE REGULATOR receiver
D3Z17_06875	COG3850	Histidine kinase
D3Z17_06875	COG5002	protein histidine kinase activity
D3Z17_06880	COG3212	peptidase
D3Z17_06885	COG3212	peptidase
D3Z17_06900	COG2239	Acts as a magnesium transporter
D3Z17_06905	COG0789	Transcriptional regulator
D3Z17_06920	COG1846	Transcriptional regulator
D3Z17_06925	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3Z17_06930	COG0726	polysaccharide deacetylase
D3Z17_06935	COG1408	metallophosphoesterase
D3Z17_06945	COG0463	Glycosyl transferase, family 2
D3Z17_06950	COG3285	dna ligase
D3Z17_06950	COG1793	dna ligase
D3Z17_06955	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D3Z17_06960	COG5001	Diguanylate cyclase
D3Z17_06960	COG3300	MHYT domain
D3Z17_06965	COG0586	Pfam SNARE associated Golgi protein
D3Z17_06970	COG0861	Integral membrane protein TerC family
D3Z17_06975	COG1191	sigma factor activity
D3Z17_06995	COG0501	Belongs to the peptidase M48B family
D3Z17_07000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3Z17_07015	COG3594	Acyltransferase
D3Z17_07020	COG5002	protein histidine kinase activity
D3Z17_07025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3Z17_07030	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D3Z17_07035	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D3Z17_07040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3Z17_07045	COG0436	Aminotransferase
D3Z17_07050	COG1850	ribulose-bisphosphate carboxylase activity
D3Z17_07055	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D3Z17_07060	COG0235	Class ii aldolase
D3Z17_07065	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D3Z17_07070	COG3339	Conserved Protein
D3Z17_07085	COG3852	Histidine kinase
D3Z17_07090	COG1846	Transcriptional regulator
D3Z17_07095	COG1360	Flagellar Motor Protein
D3Z17_07100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D3Z17_07110	COG0542	response to heat
D3Z17_07115	COG3949	Membrane
D3Z17_07120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D3Z17_07125	COG0720	synthase
D3Z17_07130	COG0602	queuosine metabolic process
D3Z17_07135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D3Z17_07140	COG1733	regulation of RNA biosynthetic process
D3Z17_07145	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_07150	COG1388	LysM domain
D3Z17_07150	COG4641	Protein conserved in bacteria
D3Z17_07155	COG1388	LysM domain
D3Z17_07160	COG3858	chitin binding
D3Z17_07165	COG3858	chitin binding
D3Z17_07175	COG4873	Protein conserved in bacteria
D3Z17_07185	COG3773	Cell wall hydrolase
D3Z17_07190	COG2244	polysaccharide biosynthetic process
D3Z17_07195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_07200	COG2217	Heavy metal translocating P-type atpase
D3Z17_07210	COG0006	proline dipeptidase activity
D3Z17_07215	COG1609	Transcriptional regulator
D3Z17_07220	COG3711	transcriptional antiterminator
D3Z17_07225	COG2190	(PTS) system
D3Z17_07225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_07225	COG1263	PTS System
D3Z17_07230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z17_07235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3Z17_07245	COG1533	DNA photolyase activity
D3Z17_07250	COG0456	acetyltransferase
D3Z17_07255	COG0840	transmembrane signaling receptor activity
D3Z17_07260	COG2084	Dehydrogenase
D3Z17_07265	COG4257	antibiotic catabolic process
D3Z17_07270	COG2340	Cysteine-rich secretory protein family
D3Z17_07275	COG0768	penicillin binding
D3Z17_07280	COG4191	Histidine kinase
D3Z17_07295	COG0784	Response regulator, receiver
D3Z17_07295	COG0835	chemotaxis
D3Z17_07305	COG2814	Major facilitator Superfamily
D3Z17_07310	COG1376	ErfK ybiS ycfS ynhG family protein
D3Z17_07315	COG1408	metallophosphoesterase
D3Z17_07320	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_07325	COG2200	EAL domain
D3Z17_07330	COG4703	Protein of unknown function (DUF1797)
D3Z17_07335	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D3Z17_07345	COG0517	IMP dehydrogenase activity
D3Z17_07350	COG0583	DNA-binding transcription factor activity
D3Z17_07355	COG0716	FMN binding
D3Z17_07365	COG0716	FMN binding
D3Z17_07370	COG2171	N-acyltransferase activity
D3Z17_07375	COG1473	amidohydrolase
D3Z17_07385	COG0668	transmembrane transport
D3Z17_07390	COG0450	alkyl hydroperoxide reductase
D3Z17_07395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_07410	COG0746	molybdenum cofactor guanylyltransferase activity
D3Z17_07415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3Z17_07420	COG0303	'Molybdopterin
D3Z17_07425	COG1763	Mo-molybdopterin cofactor biosynthetic process
D3Z17_07430	COG0314	molybdopterin synthase activity
D3Z17_07435	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D3Z17_07440	COG1132	(ABC) transporter
D3Z17_07445	COG1132	(ABC) transporter
D3Z17_07455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3Z17_07460	COG1136	(ABC) transporter
D3Z17_07465	COG0577	efflux transmembrane transporter activity
D3Z17_07470	COG1349	DNA-binding transcription factor activity
D3Z17_07475	COG1105	Belongs to the carbohydrate kinase PfkB family
D3Z17_07480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3Z17_07480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3Z17_07480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z17_07485	COG0681	Belongs to the peptidase S26 family
D3Z17_07495	COG0488	(ABC) transporter
D3Z17_07500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3Z17_07505	COG2309	aminopeptidase activity
D3Z17_07515	COG1077	Cell shape determining protein MreB Mrl
D3Z17_07520	COG2002	toxin-antitoxin pair type II binding
D3Z17_07525	COG3852	Histidine kinase
D3Z17_07530	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D3Z17_07530	COG2105	PFAM AIG2 family protein
D3Z17_07535	COG0569	domain protein
D3Z17_07540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D3Z17_07545	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D3Z17_07555	COG0561	phosphatase activity
D3Z17_07560	COG0242	peptide deformylase activity
D3Z17_07570	COG0497	DNA recombination
D3Z17_07575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3Z17_07580	COG0022	dehydrogenase e1 component
D3Z17_07585	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3Z17_07590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3Z17_07595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_07605	COG1982	Orn Lys Arg decarboxylase major
D3Z17_07610	COG4476	Belongs to the UPF0223 family
D3Z17_07615	COG4493	Belongs to the UPF0637 family
D3Z17_07625	COG0483	inositol monophosphate 1-phosphatase activity
D3Z17_07635	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D3Z17_07655	COG1595	DNA-templated transcription, initiation
D3Z17_07685	COG4896	Protein conserved in bacteria
D3Z17_07695	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D3Z17_07700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D3Z17_07705	COG2066	Belongs to the glutaminase family
D3Z17_07710	COG4838	Belongs to the UPF0358 family
D3Z17_07715	COG0772	Belongs to the SEDS family
D3Z17_07720	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D3Z17_07725	COG1612	heme a metabolic process
D3Z17_07730	COG0109	protoheme IX farnesyltransferase activity
D3Z17_07735	COG2010	Cytochrome c
D3Z17_07735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3Z17_07740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3Z17_07745	COG1845	cytochrome c oxidase, subunit III
D3Z17_07750	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D3Z17_07755	COG3336	cytochrome c oxidase
D3Z17_07765	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D3Z17_07770	COG2340	Cysteine-rich secretory protein family
D3Z17_07785	COG3679	Belongs to the UPF0342 family
D3Z17_07790	COG4471	UPF0298 protein
D3Z17_07795	COG0742	ribosomal rna small subunit methyltransferase
D3Z17_07800	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D3Z17_07805	COG3314	Sporulation integral membrane protein YlbJ
D3Z17_07810	COG1752	Esterase of the alpha-beta hydrolase superfamily
D3Z17_07815	COG3480	Lon protease (S16) C-terminal proteolytic domain
D3Z17_07820	COG1323	Belongs to the UPF0348 family
D3Z17_07830	COG1399	metal-binding, possibly nucleic acid-binding protein
D3Z17_07835	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D3Z17_07845	COG0454	-acetyltransferase
D3Z17_07850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3Z17_07855	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D3Z17_07860	COG2001	Belongs to the MraZ family
D3Z17_07865	COG0275	rRNA processing
D3Z17_07870	COG4839	cell division protein FtsL
D3Z17_07880	COG0768	penicillin binding
D3Z17_07885	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D3Z17_07890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3Z17_07895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D3Z17_07900	COG0772	Belongs to the SEDS family
D3Z17_07905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3Z17_07910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D3Z17_07915	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D3Z17_07920	COG3879	Bacterial protein of unknown function (DUF881)
D3Z17_07925	COG3879	Bacterial protein of unknown function (DUF881)
D3Z17_07930	COG3856	small basic protein
D3Z17_07935	COG0849	cell division
D3Z17_07940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D3Z17_07945	COG1404	Belongs to the peptidase S8 family
D3Z17_07945	COG4412	M6 family metalloprotease domain protein
D3Z17_07955	COG1191	sigma factor activity
D3Z17_07960	COG1191	sigma factor activity
D3Z17_07965	COG1119	ATPase activity
D3Z17_07970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3Z17_07975	COG1873	PFAM PRC-barrel domain
D3Z17_07985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D3Z17_07990	COG1799	cell septum assembly
D3Z17_07995	COG0762	integral membrane protein
D3Z17_08000	COG2302	S4 RNA-binding domain
D3Z17_08005	COG3599	regulation of cell shape
D3Z17_08010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D3Z17_08015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3Z17_08020	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D3Z17_08025	COG0564	pseudouridine synthase activity
D3Z17_08030	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D3Z17_08035	COG2233	PERMEase
D3Z17_08040	COG0540	Belongs to the ATCase OTCase family
D3Z17_08045	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3Z17_08050	COG0505	Belongs to the CarA family
D3Z17_08055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3Z17_08060	COG0543	2 iron, 2 sulfur cluster binding
D3Z17_08065	COG0167	dihydroorotate dehydrogenase activity
D3Z17_08070	COG0284	orotidine-5'-phosphate decarboxylase activity
D3Z17_08075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D3Z17_08080	COG0175	sulfate reduction
D3Z17_08085	COG0306	phosphate transporter
D3Z17_08090	COG2046	Belongs to the sulfate adenylyltransferase family
D3Z17_08095	COG0529	Catalyzes the synthesis of activated sulfate
D3Z17_08100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3Z17_08105	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D3Z17_08110	COG1648	precorrin-2 dehydrogenase activity
D3Z17_08120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D3Z17_08125	COG1561	YicC-like family, N-terminal region
D3Z17_08130	COG2052	Domain of unknown function (DUF370)
D3Z17_08135	COG0194	GDP metabolic process
D3Z17_08140	COG1758	RNA polymerase activity
D3Z17_08145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3Z17_08150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D3Z17_08155	COG0242	peptide deformylase activity
D3Z17_08160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D3Z17_08165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D3Z17_08165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3Z17_08170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D3Z17_08175	COG0631	protein serine/threonine phosphatase activity
D3Z17_08180	COG2815	serine threonine protein kinase
D3Z17_08180	COG0515	serine threonine protein kinase
D3Z17_08185	COG1162	GTPase activity
D3Z17_08190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D3Z17_08195	COG1564	THIamine pyrophosphokinase
D3Z17_08205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D3Z17_08210	COG1302	Protein conserved in bacteria
D3Z17_08215	COG1461	Dihydroxyacetone kinase
D3Z17_08220	COG1760	l-serine dehydratase
D3Z17_08225	COG1760	l-serine dehydratase
D3Z17_08230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D3Z17_08235	COG1349	DNA-binding transcription factor activity
D3Z17_08235	COG2050	protein possibly involved in aromatic compounds catabolism
D3Z17_08240	COG0416	fatty acid biosynthetic process
D3Z17_08245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3Z17_08250	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_08255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z17_08260	COG0571	ribonuclease III activity
D3Z17_08265	COG1196	nuclear chromosome segregation
D3Z17_08270	COG0552	protein localization to endoplasmic reticulum
D3Z17_08280	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D3Z17_08285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D3Z17_08290	COG0228	four-way junction DNA binding
D3Z17_08295	COG1837	Belongs to the UPF0109 family
D3Z17_08305	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D3Z17_08310	COG0336	Belongs to the RNA methyltransferase TrmD family
D3Z17_08315	COG0335	large ribosomal subunit rRNA binding
D3Z17_08320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D3Z17_08325	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D3Z17_08335	COG2257	FlhB HrpN YscU SpaS Family
D3Z17_08340	COG0045	succinate-CoA ligase (ADP-forming) activity
D3Z17_08345	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D3Z17_08350	COG0758	DNA mediated transformation
D3Z17_08355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3Z17_08360	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D3Z17_08365	COG4974	Belongs to the 'phage' integrase family
D3Z17_08370	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D3Z17_08375	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D3Z17_08380	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D3Z17_08385	COG1815	bacterial-type flagellum-dependent cell motility
D3Z17_08390	COG1558	bacterial-type flagellum-dependent cell motility
D3Z17_08395	COG1677	Flagellar hook-basal body complex protein FliE
D3Z17_08400	COG1766	The M ring may be actively involved in energy transduction
D3Z17_08405	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3Z17_08410	COG1317	bacterial-type flagellum organization
D3Z17_08415	COG1157	protein secretion by the type III secretion system
D3Z17_08420	COG2882	bacterial-type flagellum organization
D3Z17_08425	COG3334	PFAM MgtE intracellular
D3Z17_08430	COG3144	bacterial-type flagellum assembly
D3Z17_08435	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D3Z17_08440	COG4786	Flagellar basal body rod
D3Z17_08445	COG1582	Flagellar protein (FlbD)
D3Z17_08450	COG1580	Controls the rotational direction of flagella during chemotaxis
D3Z17_08455	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3Z17_08460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3Z17_08460	COG1776	CheC inhibitor of MCP methylation
D3Z17_08465	COG2201	protein-glutamate methylesterase activity
D3Z17_08475	COG1338	Plays a role in the flagellum-specific transport system
D3Z17_08480	COG1987	bacterial-type flagellum assembly
D3Z17_08485	COG1684	flagellar biosynthetic protein fliR
D3Z17_08490	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3Z17_08495	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3Z17_08500	COG1419	protein localization to endoplasmic reticulum
D3Z17_08505	COG0455	bacterial-type flagellum organization
D3Z17_08510	COG2201	protein-glutamate methylesterase activity
D3Z17_08515	COG2198	Histidine kinase
D3Z17_08515	COG0643	Histidine kinase
D3Z17_08520	COG0835	chemotaxis
D3Z17_08525	COG1776	CheC inhibitor of MCP methylation
D3Z17_08530	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D3Z17_08535	COG1191	sigma factor activity
D3Z17_08545	COG0052	Belongs to the universal ribosomal protein uS2 family
D3Z17_08550	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D3Z17_08555	COG0528	UMP kinase activity
D3Z17_08560	COG0233	cytoplasmic translational termination
D3Z17_08565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D3Z17_08570	COG4589	Belongs to the CDS family
D3Z17_08575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D3Z17_08580	COG0750	zinc metalloprotease
D3Z17_08585	COG0442	prolyl-tRNA aminoacylation
D3Z17_08590	COG2176	DNA-directed DNA polymerase activity
D3Z17_08615	COG0779	Required for maturation of 30S ribosomal subunits
D3Z17_08620	COG0195	Participates in both transcription termination and antitermination
D3Z17_08625	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D3Z17_08630	COG1358	cellular component organization or biogenesis
D3Z17_08635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D3Z17_08640	COG1550	Protein conserved in bacteria
D3Z17_08645	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D3Z17_08650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D3Z17_08655	COG0196	riboflavin kinase activity
D3Z17_08660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D3Z17_08665	COG1185	polyribonucleotide nucleotidyltransferase activity
D3Z17_08670	COG0726	polysaccharide deacetylase
D3Z17_08675	COG0612	Peptidase, M16
D3Z17_08680	COG1873	PFAM PRC-barrel domain
D3Z17_08685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3Z17_08690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3Z17_08695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3Z17_08700	COG0527	aspartate kinase activity
D3Z17_08705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3Z17_08710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D3Z17_08715	COG0740	serine-type endopeptidase activity
D3Z17_08725	COG1674	ftsk spoiiie
D3Z17_08725	COG4980	gas vesicle protein
D3Z17_08730	COG2188	Transcriptional regulator
D3Z17_08735	COG2814	Major facilitator Superfamily
D3Z17_08740	COG0612	Peptidase, M16
D3Z17_08745	COG0612	Peptidase, M16
D3Z17_08750	COG0300	oxidoreductase activity
D3Z17_08765	COG1426	Protein conserved in bacteria
D3Z17_08770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D3Z17_08775	COG1546	Belongs to the CinA family
D3Z17_08775	COG1058	Belongs to the CinA family
D3Z17_08780	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D3Z17_08785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3Z17_08790	COG1418	mRNA catabolic process
D3Z17_08795	COG1692	metallophosphoesterase
D3Z17_08800	COG2359	stage V sporulation protein S
D3Z17_08805	COG1063	alcohol dehydrogenase
D3Z17_08810	COG0156	8-amino-7-oxononanoate synthase activity
D3Z17_08815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3Z17_08820	COG4550	Control of competence regulator ComK, YlbF/YmcA
D3Z17_08830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D3Z17_08835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D3Z17_08850	COG3226	Transcriptional regulator
D3Z17_08855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z17_08865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3Z17_08870	COG3321	synthase
D3Z17_08875	COG2070	2-Nitropropane dioxygenase
D3Z17_08875	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3Z17_08880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z17_08885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3Z17_08890	COG3425	synthase
D3Z17_08895	COG1024	Enoyl-CoA hydratase
D3Z17_08900	COG1024	Enoyl-CoA hydratase
D3Z17_08905	COG0300	oxidoreductase activity
D3Z17_08905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z17_08905	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_08905	COG3321	synthase
D3Z17_08905	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z17_08910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z17_08910	COG0300	oxidoreductase activity
D3Z17_08910	COG4221	oxidoreductase activity
D3Z17_08910	COG3321	synthase
D3Z17_08915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3Z17_08915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z17_08915	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_08915	COG3321	synthase
D3Z17_08915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z17_08920	COG3321	synthase
D3Z17_08920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z17_08920	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_08920	COG4221	oxidoreductase activity
D3Z17_08925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3Z17_08925	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D3Z17_08925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z17_08925	COG3321	synthase
D3Z17_08930	COG2124	cytochrome p450
D3Z17_08940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z17_08945	COG1404	Belongs to the peptidase S8 family
D3Z17_08955	COG4195	phage-related replication protein
D3Z17_08960	COG1764	response to oxidative stress
D3Z17_08965	COG2076	Multidrug Resistance protein
D3Z17_08970	COG2076	Multidrug Resistance protein
D3Z17_08985	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D3Z17_08990	COG1923	regulation of RNA biosynthetic process
D3Z17_09005	COG1780	Probably involved in ribonucleotide reductase function
D3Z17_09010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3Z17_09015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3Z17_09020	COG4112	unkown
D3Z17_09025	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z17_09035	COG0464	growth
D3Z17_09050	COG1525	nuclease
D3Z17_09060	COG4282	regulation of fungal-type cell wall biogenesis
D3Z17_09065	COG5444	nuclease activity
D3Z17_09080	COG0457	Tetratricopeptide repeat
D3Z17_09095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3Z17_09110	COG3271	cysteine-type peptidase activity
D3Z17_09110	COG2274	protein secretion by the type I secretion system
D3Z17_09115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_09120	COG0463	Glycosyl transferase, family 2
D3Z17_09125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D3Z17_09140	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3Z17_09140	COG3409	Peptidoglycan-binding domain 1 protein
D3Z17_09145	COG4632	Exopolysaccharide biosynthesis protein
D3Z17_09145	COG5434	Belongs to the glycosyl hydrolase 28 family
D3Z17_09155	COG2433	Pfam Transposase IS66
D3Z17_09165	COG1196	nuclear chromosome segregation
D3Z17_09165	COG0739	heme binding
D3Z17_09165	COG0741	lytic transglycosylase activity
D3Z17_09190	COG0582	viral genome integration into host DNA
D3Z17_09290	COG4373	Mu-like prophage FluMu protein gp28
D3Z17_09325	COG0776	regulation of translation
D3Z17_09390	COG3655	Transcriptional regulator
D3Z17_09455	COG0582	viral genome integration into host DNA
D3Z17_09470	COG3655	Transcriptional regulator
D3Z17_09575	COG1793	dna ligase
D3Z17_09580	COG2135	peptidase activity
D3Z17_09600	COG4195	phage-related replication protein
D3Z17_09605	COG3420	alginic acid biosynthetic process
D3Z17_09605	COG5434	Belongs to the glycosyl hydrolase 28 family
D3Z17_09630	COG2887	Belongs to the helicase family. UvrD subfamily
D3Z17_09640	COG0305	Participates in initiation and elongation during chromosome replication
D3Z17_09645	COG0358	DNA primase activity
D3Z17_09650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3Z17_09655	COG0587	DNA-directed DNA polymerase activity
D3Z17_09660	COG3584	3D domain protein
D3Z17_09685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3Z17_09700	COG0270	DNA (cytosine-5-)-methyltransferase activity
D3Z17_09800	COG1780	Probably involved in ribonucleotide reductase function
D3Z17_09805	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3Z17_09805	COG1372	Participates in initiation and elongation during chromosome replication
D3Z17_09815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3Z17_09835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_09845	COG0756	dUTP diphosphatase activity
D3Z17_09880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3Z17_09910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3Z17_09955	COG3331	DNA recombination
D3Z17_09970	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D3Z17_09975	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D3Z17_09980	COG0789	Transcriptional regulator
D3Z17_09985	COG0174	glutamine synthetase
D3Z17_10010	COG4282	regulation of fungal-type cell wall biogenesis
D3Z17_10020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z17_10050	COG0135	phosphoribosylanthranilate isomerase activity
D3Z17_10055	COG2211	Major facilitator Superfamily
D3Z17_10060	COG3507	Belongs to the glycosyl hydrolase 43 family
D3Z17_10065	COG1940	carbohydrate kinase activity
D3Z17_10070	COG2115	Belongs to the xylose isomerase family
D3Z17_10075	COG1070	Carbohydrate kinase
D3Z17_10085	COG1525	nuclease
D3Z17_10090	COG2814	Major facilitator Superfamily
D3Z17_10095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3Z17_10110	COG0756	dUTP diphosphatase activity
D3Z17_10150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3Z17_10160	COG3832	glyoxalase III activity
D3Z17_10175	COG0697	spore germination
D3Z17_10180	COG0531	amino acid
D3Z17_10210	COG4195	phage-related replication protein
D3Z17_10220	COG0346	lactoylglutathione lyase activity
D3Z17_10230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D3Z17_10235	COG1388	LysM domain
D3Z17_10240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3Z17_10245	COG4224	UPF0291 protein
D3Z17_10250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D3Z17_10260	COG3763	UPF0154 protein
D3Z17_10270	COG0785	Cytochrome C biogenesis protein
D3Z17_10275	COG2201	protein-glutamate methylesterase activity
D3Z17_10280	COG4846	Membrane protein involved in cytochrome C biogenesis
D3Z17_10290	COG0071	Belongs to the small heat shock protein (HSP20) family
D3Z17_10305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D3Z17_10310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_10330	COG0824	Thioesterase
D3Z17_10340	COG4841	protein insertion into membrane
D3Z17_10345	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D3Z17_10350	COG1832	CoA-binding protein
D3Z17_10355	COG0187	DNA topoisomerase II activity
D3Z17_10360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3Z17_10370	COG1115	amino acid carrier protein
D3Z17_10375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D3Z17_10385	COG5520	Belongs to the glycosyl hydrolase 30 family
D3Z17_10390	COG3507	Belongs to the glycosyl hydrolase 43 family
D3Z17_10395	COG2246	polysaccharide biosynthetic process
D3Z17_10400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3Z17_10405	COG0586	Pfam SNARE associated Golgi protein
D3Z17_10410	COG2404	hydrolase activity, acting on ester bonds
D3Z17_10415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D3Z17_10420	COG1024	Enoyl-CoA hydratase
D3Z17_10425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D3Z17_10430	COG0511	ligase activity, forming carbon-carbon bonds
D3Z17_10435	COG0439	Biotin carboxylase
D3Z17_10440	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z17_10445	COG1960	acyl-CoA dehydrogenase activity
D3Z17_10455	COG1649	PFAM Uncharacterised BCR, COG1649
D3Z17_10465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z17_10465	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D3Z17_10490	COG2027	D-alanyl-D-alanine carboxypeptidase
D3Z17_10495	COG2017	converts alpha-aldose to the beta-anomer
D3Z17_10500	COG0534	Mate efflux family protein
D3Z17_10515	COG0582	viral genome integration into host DNA
D3Z17_10520	COG0166	Belongs to the GPI family
D3Z17_10525	COG0405	Gamma-glutamyltransferase
D3Z17_10530	COG0583	DNA-binding transcription factor activity
D3Z17_10535	COG0604	alcohol dehydrogenase
D3Z17_10540	COG0493	'glutamate synthase
D3Z17_10545	COG0067	glutamate synthase
D3Z17_10545	COG0069	glutamate synthase activity
D3Z17_10545	COG0070	glutamate synthase
D3Z17_10550	COG0583	DNA-binding transcription factor activity
D3Z17_10555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D3Z17_10560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3Z17_10570	COG0300	oxidoreductase activity
D3Z17_10575	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D3Z17_10585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z17_10600	COG1131	(ABC) transporter
D3Z17_10610	COG2814	Major facilitator Superfamily
D3Z17_10615	COG1070	Carbohydrate kinase
D3Z17_10620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3Z17_10625	COG0243	molybdopterin cofactor binding
D3Z17_10650	COG0840	transmembrane signaling receptor activity
D3Z17_10650	COG5278	phosphoserine phosphatase activity
D3Z17_10655	COG2368	4-hydroxyphenylacetate
D3Z17_10660	COG4305	rare lipoprotein A
D3Z17_10665	COG3619	membrane
D3Z17_10670	COG3866	Pectate lyase
D3Z17_10675	COG2135	peptidase activity
D3Z17_10685	COG2140	Oxalate decarboxylase
D3Z17_10705	COG2720	vancomycin resistance protein
D3Z17_10720	COG3739	integral membrane protein
D3Z17_10725	COG0583	DNA-binding transcription factor activity
D3Z17_10730	COG0697	spore germination
D3Z17_10740	COG0693	protein deglycase activity
D3Z17_10745	COG2367	Beta-lactamase
D3Z17_10765	COG3848	Pyruvate phosphate dikinase
D3Z17_10765	COG0574	Belongs to the PEP-utilizing enzyme family
D3Z17_10770	COG0726	polysaccharide deacetylase
D3Z17_10780	COG2314	TM2 domain
D3Z17_10810	COG3655	Transcriptional regulator
D3Z17_10845	COG0457	Tetratricopeptide repeat
D3Z17_10855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3Z17_10865	COG4282	regulation of fungal-type cell wall biogenesis
D3Z17_10870	COG1231	oxidoreductase activity
D3Z17_10875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3Z17_10880	COG0662	Cupin 2, conserved barrel domain protein
D3Z17_10880	COG2207	Transcriptional regulator
D3Z17_10885	COG0456	acetyltransferase
D3Z17_10890	COG1309	transcriptional regulator
D3Z17_10895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z17_10900	COG3708	Transcriptional regulator
D3Z17_10905	COG2378	regulation of single-species biofilm formation
D3Z17_10915	COG0640	Transcriptional regulator
D3Z17_10920	COG0741	lytic transglycosylase activity
D3Z17_10925	COG2322	membrane
D3Z17_10940	COG1619	proteins homologs of microcin C7 resistance protein MccF
D3Z17_10945	COG3239	Fatty acid desaturase
D3Z17_10950	COG4585	Histidine kinase
D3Z17_10955	COG2197	response regulator
D3Z17_10960	COG1388	LysM domain
D3Z17_10960	COG3584	3D domain protein
D3Z17_10965	COG0514	ATP-dependent DNA helicase (RecQ)
D3Z17_10980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D3Z17_10985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3Z17_11000	COG0071	Belongs to the small heat shock protein (HSP20) family
D3Z17_11025	COG1012	belongs to the aldehyde dehydrogenase family
D3Z17_11030	COG1657	PFAM Prenyltransferase squalene oxidase
D3Z17_11035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D3Z17_11040	COG0733	neurotransmitter:sodium symporter activity
D3Z17_11045	COG0385	Bile acid
D3Z17_11050	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3Z17_11055	COG0567	Dehydrogenase, E1 component
D3Z17_11060	COG4548	von Willebrand factor, type A
D3Z17_11065	COG0714	Associated with various cellular activities
D3Z17_11070	COG2032	superoxide dismutase activity
D3Z17_11075	COG1388	LysM domain
D3Z17_11075	COG0791	NLP P60 protein
D3Z17_11080	COG1819	glycosyl
D3Z17_11085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D3Z17_11090	COG0534	Mate efflux family protein
D3Z17_11095	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z17_11100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3Z17_11105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3Z17_11115	COG2962	Rard protein
D3Z17_11130	COG2610	gluconate transmembrane transporter activity
D3Z17_11135	COG1942	4-Oxalocrotonate Tautomerase
D3Z17_11140	COG1733	regulation of RNA biosynthetic process
D3Z17_11145	COG0778	Nitroreductase
D3Z17_11150	COG0400	carboxylic ester hydrolase activity
D3Z17_11155	COG0346	lactoylglutathione lyase activity
D3Z17_11165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3Z17_11170	COG0793	Belongs to the peptidase S41A family
D3Z17_11170	COG3409	Peptidoglycan-binding domain 1 protein
D3Z17_11175	COG2226	methyltransferase
D3Z17_11185	COG1876	peptidase activity
D3Z17_11190	COG0813	purine-nucleoside phosphorylase activity
D3Z17_11205	COG0671	phosphoesterase, PA-phosphatase related
D3Z17_11225	COG4479	Belongs to the UPF0346 family
D3Z17_11235	COG1509	lysine 2,3-aminomutase activity
D3Z17_11240	COG0456	acetyltransferase
D3Z17_11245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3Z17_11250	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D3Z17_11255	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D3Z17_11260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3Z17_11270	COG0456	acetyltransferase
D3Z17_11275	COG0463	Glycosyl transferase, family 2
D3Z17_11290	COG4641	Protein conserved in bacteria
D3Z17_11295	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D3Z17_11300	COG1086	Polysaccharide biosynthesis protein
D3Z17_11305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D3Z17_11310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D3Z17_11315	COG1846	Transcriptional regulator
D3Z17_11320	COG0534	Mate efflux family protein
D3Z17_11330	COG4698	Protein conserved in bacteria
D3Z17_11335	COG2755	lipolytic protein G-D-S-L family
D3Z17_11340	COG1999	signal sequence binding
D3Z17_11350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D3Z17_11355	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D3Z17_11360	COG1272	protein, Hemolysin III
D3Z17_11365	COG0204	Acyl-transferase
D3Z17_11370	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3Z17_11375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D3Z17_11380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D3Z17_11390	COG2136	Putative SAM-dependent methyltransferase
D3Z17_11390	COG2521	methyltransferase
D3Z17_11400	COG0129	dihydroxy-acid dehydratase activity
D3Z17_11405	COG1413	lyase activity
D3Z17_11410	COG1418	mRNA catabolic process
D3Z17_11415	COG0386	Belongs to the glutathione peroxidase family
D3Z17_11420	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D3Z17_11425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3Z17_11430	COG1278	Cold shock
D3Z17_11450	COG0328	RNA-DNA hybrid ribonuclease activity
D3Z17_11455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D3Z17_11460	COG0328	RNA-DNA hybrid ribonuclease activity
D3Z17_11470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3Z17_11485	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D3Z17_11495	COG1755	Isoprenylcysteine carboxyl methyltransferase
D3Z17_11500	COG3424	synthase
D3Z17_11505	COG2233	PERMEase
D3Z17_11510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3Z17_11515	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D3Z17_11525	COG0800	Aldolase
D3Z17_11530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3Z17_11535	COG1609	Transcriptional regulator
D3Z17_11540	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D3Z17_11545	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_11550	COG1199	ATP-dependent helicase activity
D3Z17_11565	COG0116	Belongs to the methyltransferase superfamily
D3Z17_11580	COG4474	Belongs to the UPF0398 family
D3Z17_11590	COG3359	exonuclease
D3Z17_11595	COG1111	helicase
D3Z17_11595	COG1205	dead DEAH box helicase
D3Z17_11600	COG2190	(PTS) system
D3Z17_11605	COG0071	Belongs to the small heat shock protein (HSP20) family
D3Z17_11640	COG3331	DNA recombination
D3Z17_11645	COG4499	WXG100 protein secretion system (Wss), protein YukC
D3Z17_11645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3Z17_11655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D3Z17_11660	COG3935	DnaD domain protein
D3Z17_11670	COG0436	Aminotransferase
D3Z17_11675	COG5353	protein conserved in bacteria
D3Z17_11685	COG1199	ATP-dependent helicase activity
D3Z17_11685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3Z17_11690	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D3Z17_11695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D3Z17_11700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D3Z17_11705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D3Z17_11705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D3Z17_11710	COG0617	tRNA 3'-terminal CCA addition
D3Z17_11715	COG0438	transferase activity, transferring glycosyl groups
D3Z17_11720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3Z17_11725	COG1803	Methylglyoxal synthase
D3Z17_11730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D3Z17_11735	COG1694	Mazg nucleotide pyrophosphohydrolase
D3Z17_11740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z17_11750	COG4347	Protein of unknown function (DUF1405)
D3Z17_11755	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D3Z17_11755	COG2010	Cytochrome c
D3Z17_11760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D3Z17_11765	COG0723	plastoquinol--plastocyanin reductase activity
D3Z17_11775	COG5582	Belongs to the UPF0302 family
D3Z17_11780	COG0457	Tetratricopeptide repeat
D3Z17_11785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D3Z17_11790	COG0287	Prephenate dehydrogenase
D3Z17_11795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3Z17_11805	COG0133	tryptophan synthase activity
D3Z17_11810	COG0135	phosphoribosylanthranilate isomerase activity
D3Z17_11820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D3Z17_11825	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3Z17_11830	COG4401	Chorismate mutase type I
D3Z17_11835	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D3Z17_11840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D3Z17_11845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D3Z17_11850	COG0105	UTP biosynthetic process
D3Z17_11855	COG0142	geranyltranstransferase activity
D3Z17_11860	COG2226	methyltransferase
D3Z17_11865	COG0142	geranyltranstransferase activity
D3Z17_11875	COG0302	gtp cyclohydrolase
D3Z17_11880	COG0776	regulation of translation
D3Z17_11885	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D3Z17_11900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D3Z17_11905	COG1160	GTP binding
D3Z17_11930	COG1304	FMN binding
D3Z17_11935	COG0539	negative regulation of cytoplasmic translation
D3Z17_11940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D3Z17_11950	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D3Z17_11955	COG2959	enzyme of heme biosynthesis
D3Z17_11960	COG3773	Cell wall hydrolase
D3Z17_11960	COG3409	Peptidoglycan-binding domain 1 protein
D3Z17_11965	COG2339	peptidase activity
D3Z17_11970	COG0492	ferredoxin-NADP+ reductase activity
D3Z17_11975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3Z17_11980	COG4862	establishment of competence for transformation
D3Z17_11985	COG1408	metallophosphoesterase
D3Z17_11995	COG1388	LysM domain
D3Z17_12000	COG1266	CAAX protease self-immunity
D3Z17_12005	COG0514	ATP-dependent DNA helicase (RecQ)
D3Z17_12010	COG4955	Helix-turn-helix domain
D3Z17_12015	COG1141	Ferredoxin
D3Z17_12020	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D3Z17_12025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3Z17_12030	COG0710	3-dehydroquinate dehydratase activity
D3Z17_12040	COG1595	DNA-templated transcription, initiation
D3Z17_12045	COG5002	protein histidine kinase activity
D3Z17_12050	COG0745	RESPONSE REGULATOR receiver
D3Z17_12055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3Z17_12060	COG1333	cytochrome c biogenesis protein
D3Z17_12065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_12070	COG1187	pseudouridine synthase activity
D3Z17_12075	COG0700	Nucleoside recognition
D3Z17_12080	COG2715	membrane protein required for spore maturation
D3Z17_12085	COG1686	Belongs to the peptidase S11 family
D3Z17_12095	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D3Z17_12100	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D3Z17_12105	COG1547	Domain of unknown function (DUF309)
D3Z17_12110	COG0456	acetyltransferase
D3Z17_12115	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D3Z17_12120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3Z17_12120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3Z17_12125	COG0307	riboflavin synthase, alpha
D3Z17_12130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3Z17_12130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3Z17_12140	COG0681	Belongs to the peptidase S26 family
D3Z17_12155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D3Z17_12165	COG4086	secreted protein
D3Z17_12170	COG0019	diaminopimelate decarboxylase activity
D3Z17_12175	COG0697	spore germination
D3Z17_12190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3Z17_12210	COG1191	sigma factor activity
D3Z17_12215	COG2172	sigma factor antagonist activity
D3Z17_12220	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z17_12225	COG1686	Belongs to the peptidase S11 family
D3Z17_12230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D3Z17_12235	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D3Z17_12240	COG4974	Belongs to the 'phage' integrase family
D3Z17_12250	COG0735	belongs to the Fur family
D3Z17_12255	COG1300	Membrane
D3Z17_12265	COG0281	malic enzyme
D3Z17_12270	COG1757	Na H antiporter
D3Z17_12275	COG1027	Aspartate ammonia-lyase
D3Z17_12280	COG0252	asparaginase activity
D3Z17_12285	COG1396	sequence-specific DNA binding
D3Z17_12290	COG1379	DNA repair
D3Z17_12305	COG0667	Aldo Keto reductase
D3Z17_12315	COG1073	alpha beta
D3Z17_12325	COG4918	Iron-sulphur cluster biosynthesis
D3Z17_12330	COG0456	acetyltransferase
D3Z17_12330	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D3Z17_12335	COG2329	Antibiotic biosynthesis monooxygenase
D3Z17_12340	COG0456	acetyltransferase
D3Z17_12350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3Z17_12360	COG2211	Major facilitator Superfamily
D3Z17_12370	COG0346	lactoylglutathione lyase activity
D3Z17_12375	COG1072	(Pantothenic acid kinase))
D3Z17_12380	COG3048	D-serine ammonia-lyase activity
D3Z17_12385	COG0300	oxidoreductase activity
D3Z17_12390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z17_12395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3Z17_12400	COG4187	Peptidase family M20/M25/M40
D3Z17_12405	COG1902	pentaerythritol trinitrate reductase activity
D3Z17_12410	COG0596	Alpha beta hydrolase
D3Z17_12420	COG1234	tRNA 3'-trailer cleavage
D3Z17_12425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D3Z17_12430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D3Z17_12435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3Z17_12445	COG0706	membrane insertase activity
D3Z17_12450	COG3361	conserved protein (COG2071)
D3Z17_12455	COG2195	Cleaves the N-terminal amino acid of tripeptides
D3Z17_12460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D3Z17_12465	COG0346	lactoylglutathione lyase activity
D3Z17_12470	COG1376	ErfK ybiS ycfS ynhG family protein
D3Z17_12475	COG4129	membrane
D3Z17_12480	COG1126	abc transporter atp-binding protein
D3Z17_12485	COG0765	amino acid transport
D3Z17_12490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z17_12500	COG1597	lipid kinase activity
D3Z17_12505	COG2814	Major facilitator Superfamily
D3Z17_12515	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3Z17_12520	COG0022	dehydrogenase e1 component
D3Z17_12525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3Z17_12530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3Z17_12535	COG3426	butyrate kinase activity
D3Z17_12540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3Z17_12545	COG0280	phosphate acetyltransferase
D3Z17_12550	COG3829	transcription factor binding
D3Z17_12550	COG3290	protein histidine kinase activity
D3Z17_12560	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D3Z17_12565	COG2079	MmgE PrpD family protein
D3Z17_12570	COG0372	Belongs to the citrate synthase family
D3Z17_12575	COG1960	acyl-CoA dehydrogenase activity
D3Z17_12580	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3Z17_12585	COG0183	Belongs to the thiolase family
D3Z17_12590	COG0584	glycerophosphoryl diester phosphodiesterase
D3Z17_12595	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z17_12605	COG1902	pentaerythritol trinitrate reductase activity
D3Z17_12610	COG0745	RESPONSE REGULATOR receiver
D3Z17_12615	COG0750	zinc metalloprotease
D3Z17_12620	COG0497	DNA recombination
D3Z17_12625	COG1438	arginine binding
D3Z17_12630	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D3Z17_12635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D3Z17_12640	COG0142	geranyltranstransferase activity
D3Z17_12645	COG1722	exodeoxyribonuclease VII activity
D3Z17_12650	COG1570	exodeoxyribonuclease VII activity
D3Z17_12655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D3Z17_12660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3Z17_12665	COG1302	Protein conserved in bacteria
D3Z17_12670	COG0439	Biotin carboxylase
D3Z17_12675	COG0511	ligase activity, forming carbon-carbon bonds
D3Z17_12715	COG3854	ATPases associated with a variety of cellular activities
D3Z17_12725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D3Z17_12730	COG0006	proline dipeptidase activity
D3Z17_12735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D3Z17_12745	COG3872	metal-dependent enzyme
D3Z17_12755	COG1752	Esterase of the alpha-beta hydrolase superfamily
D3Z17_12760	COG1321	iron dependent repressor
D3Z17_12765	COG0095	Lipoate-protein ligase
D3Z17_12770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3Z17_12775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D3Z17_12780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D3Z17_12785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D3Z17_12790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D3Z17_12805	COG1396	sequence-specific DNA binding
D3Z17_12815	COG0681	Belongs to the peptidase S26 family
D3Z17_12840	COG4940	Competence protein ComGF
D3Z17_12850	COG4970	Tfp pilus assembly protein FimT
D3Z17_12855	COG4537	Required for transformation and DNA binding
D3Z17_12860	COG1459	type II secretion system
D3Z17_12865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D3Z17_12875	COG0598	Magnesium transport protein CorA
D3Z17_12880	COG1253	flavin adenine dinucleotide binding
D3Z17_12885	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z17_12895	COG1393	Belongs to the ArsC family
D3Z17_12905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z17_12915	COG0011	TIGRFAM Protein of
D3Z17_12925	COG2866	Carboxypeptidase
D3Z17_12930	COG1368	sulfuric ester hydrolase activity
D3Z17_12935	COG1940	carbohydrate kinase activity
D3Z17_12940	COG4483	Protein conserved in bacteria
D3Z17_12945	COG0705	Rhomboid family
D3Z17_12945	COG0457	Tetratricopeptide repeat
D3Z17_12955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D3Z17_12960	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3Z17_12965	COG0438	transferase activity, transferring glycosyl groups
D3Z17_12980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D3Z17_12985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3Z17_12990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3Z17_12995	COG0581	inorganic phosphate transmembrane transporter activity
D3Z17_13000	COG0573	inorganic phosphate transmembrane transporter activity
D3Z17_13005	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3Z17_13015	COG0477	Major facilitator Superfamily
D3Z17_13020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D3Z17_13025	COG2839	Protein conserved in bacteria
D3Z17_13030	COG5521	maltodextrose utilization protein MalA
D3Z17_13035	COG1388	LysM domain
D3Z17_13040	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D3Z17_13045	COG4709	membrane
D3Z17_13050	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D3Z17_13055	COG0735	belongs to the Fur family
D3Z17_13060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z17_13070	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D3Z17_13075	COG0513	Belongs to the DEAD box helicase family
D3Z17_13085	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D3Z17_13090	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D3Z17_13095	COG2384	SAM-dependent methyltransferase
D3Z17_13100	COG2010	Cytochrome c
D3Z17_13110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3Z17_13115	COG0358	DNA primase activity
D3Z17_13120	COG1671	Belongs to the UPF0178 family
D3Z17_13125	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D3Z17_13130	COG0517	IMP dehydrogenase activity
D3Z17_13135	COG0751	glycine-tRNA ligase activity
D3Z17_13140	COG0752	glycyl-tRNA synthetase alpha subunit
D3Z17_13145	COG1381	Involved in DNA repair and RecF pathway recombination
D3Z17_13155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D3Z17_13160	COG0295	cytidine deaminase activity
D3Z17_13165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D3Z17_13170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D3Z17_13175	COG1480	7TM receptor with intracellular HD hydrolase
D3Z17_13180	COG1702	phosphate starvation-inducible protein PhoH
D3Z17_13185	COG0561	phosphatase activity
D3Z17_13200	COG4864	UPF0365 protein
D3Z17_13205	COG1030	water channel activity
D3Z17_13210	COG1610	YqeY-like protein
D3Z17_13215	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D3Z17_13220	COG1283	sodium-dependent phosphate transmembrane transporter activity
D3Z17_13225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3Z17_13230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D3Z17_13235	COG2264	protein methyltransferase activity
D3Z17_13240	COG0484	heat shock protein binding
D3Z17_13245	COG0443	Heat shock 70 kDa protein
D3Z17_13250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D3Z17_13255	COG1420	regulation of RNA biosynthetic process
D3Z17_13260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3Z17_13265	COG0481	GTPase activity
D3Z17_13275	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z17_13280	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D3Z17_13285	COG0268	Binds directly to 16S ribosomal RNA
D3Z17_13290	COG1466	dna polymerase III delta subunit
D3Z17_13300	COG0658	competence protein
D3Z17_13300	COG2333	competence protein COMEC
D3Z17_13305	COG2131	deaminase
D3Z17_13310	COG1555	photosystem II stabilization
D3Z17_13310	COG1596	polysaccharide export
D3Z17_13315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3Z17_13320	COG2226	methyltransferase
D3Z17_13325	COG0799	negative regulation of ribosome biogenesis
D3Z17_13330	COG1713	HD superfamily hydrolase involved in NAD metabolism
D3Z17_13335	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D3Z17_13340	COG1534	Rna-binding protein
D3Z17_13345	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D3Z17_13350	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D3Z17_13355	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D3Z17_13365	COG2755	lipolytic protein G-D-S-L family
D3Z17_13370	COG3409	Peptidoglycan-binding domain 1 protein
D3Z17_13370	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3Z17_13375	COG0398	Pfam SNARE associated Golgi protein
D3Z17_13380	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D3Z17_13390	COG3209	COG3209 Rhs family protein
D3Z17_13400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3Z17_13410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3Z17_13415	COG0798	PFAM Bile acid sodium symporter
D3Z17_13420	COG0346	lactoylglutathione lyase activity
D3Z17_13425	COG0640	Transcriptional regulator
D3Z17_13430	COG3403	YqcI/YcgG family
D3Z17_13435	COG0457	Tetratricopeptide repeat
D3Z17_13450	COG5444	nuclease activity
D3Z17_13470	COG3409	Peptidoglycan-binding domain 1 protein
D3Z17_13470	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3Z17_13475	COG4824	toxin secretion phage lysis holin
D3Z17_13505	COG3778	Protein conserved in bacteria
D3Z17_13510	COG3299	homolog of phage Mu protein gp47
D3Z17_13515	COG3628	GPW Gp25 family protein
D3Z17_13525	COG4193	domain, Protein
D3Z17_13530	COG1652	LysM domain
D3Z17_13535	COG5280	Phage tail tape measure protein TP901
D3Z17_13535	COG3953	SLT domain
D3Z17_13600	COG4653	Phage capsid family
D3Z17_13605	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D3Z17_13615	COG2369	cell adhesion
D3Z17_13620	COG5518	Phage portal protein
D3Z17_13625	COG1783	phage Terminase large subunit
D3Z17_13630	COG5484	DNA packaging
D3Z17_13640	COG3677	Transposase
D3Z17_13655	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D3Z17_13665	COG1484	DNA-dependent DNA replication
D3Z17_13670	COG3935	DnaD domain protein
D3Z17_13675	COG3723	Recombinational DNA repair protein, rece pathway
D3Z17_13680	COG5377	YqaJ viral recombinase family
D3Z17_13705	COG1476	TRANSCRIPTIONal
D3Z17_13710	COG3620	sequence-specific DNA binding
D3Z17_13720	COG0563	adenylate kinase activity
D3Z17_13725	COG2856	Zn peptidase
D3Z17_13735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3Z17_13745	COG3223	Belongs to the PsiE family
D3Z17_13750	COG5002	protein histidine kinase activity
D3Z17_13750	COG0642	Histidine kinase
D3Z17_13755	COG0745	RESPONSE REGULATOR receiver
D3Z17_13760	COG2311	Membrane
D3Z17_13765	COG0454	-acetyltransferase
D3Z17_13770	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3Z17_13780	COG0730	response to heat
D3Z17_13785	COG0425	Belongs to the sulfur carrier protein TusA family
D3Z17_13790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3Z17_13790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z17_13800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3Z17_13800	COG0425	Belongs to the sulfur carrier protein TusA family
D3Z17_13810	COG2210	Belongs to the sulfur carrier protein TusA family
D3Z17_13815	COG1937	Protein conserved in bacteria
D3Z17_13830	COG0662	Cupin 2, conserved barrel domain protein
D3Z17_13850	COG4978	Transcriptional regulator
D3Z17_13850	COG0789	Transcriptional regulator
D3Z17_13855	COG2814	Major facilitator Superfamily
D3Z17_13860	COG0456	acetyltransferase
D3Z17_13865	COG1253	flavin adenine dinucleotide binding
D3Z17_13875	COG0697	spore germination
D3Z17_13880	COG0583	DNA-binding transcription factor activity
D3Z17_13885	COG2072	flavoprotein involved in K transport
D3Z17_13890	COG1230	cation diffusion facilitator family transporter
D3Z17_13895	COG1942	4-Oxalocrotonate Tautomerase
D3Z17_13900	COG0583	DNA-binding transcription factor activity
D3Z17_13910	COG1114	Component of the transport system for branched-chain amino acids
D3Z17_13915	COG1687	branched-chain amino acid
D3Z17_13920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D3Z17_13925	COG1522	sequence-specific DNA binding
D3Z17_13930	COG2732	(Barnase) inhibitor
D3Z17_13935	COG2124	cytochrome p450
D3Z17_13945	COG1335	isochorismatase
D3Z17_13960	COG2318	DinB family
D3Z17_13970	COG2070	2-Nitropropane dioxygenase
D3Z17_13995	COG2186	Transcriptional regulator
D3Z17_14010	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_14015	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D3Z17_14020	COG3959	Transketolase, thiamine diphosphate binding domain
D3Z17_14035	COG4978	Transcriptional regulator
D3Z17_14035	COG0789	Transcriptional regulator
D3Z17_14040	COG2315	Protein conserved in bacteria
D3Z17_14050	COG3443	Belongs to the bacterial solute-binding protein 9 family
D3Z17_14055	COG1595	DNA-templated transcription, initiation
D3Z17_14060	COG0667	Aldo Keto reductase
D3Z17_14065	COG2851	Citrate transporter
D3Z17_14070	COG0583	DNA-binding transcription factor activity
D3Z17_14075	COG2828	Protein conserved in bacteria
D3Z17_14080	COG3409	Peptidoglycan-binding domain 1 protein
D3Z17_14085	COG5566	PFAM Mor transcription activator
D3Z17_14090	COG0596	Alpha beta hydrolase
D3Z17_14095	COG4991	sh3 domain protein
D3Z17_14100	COG4991	sh3 domain protein
D3Z17_14105	COG0346	lactoylglutathione lyase activity
D3Z17_14115	COG5577	PFAM Coat F domain
D3Z17_14120	COG1063	alcohol dehydrogenase
D3Z17_14130	COG5577	PFAM Coat F domain
D3Z17_14135	COG0789	Transcriptional regulator
D3Z17_14145	COG1064	alcohol dehydrogenase
D3Z17_14150	COG0693	protein deglycase activity
D3Z17_14155	COG1621	beta-fructofuranosidase activity
D3Z17_14160	COG3716	PTS system mannose fructose sorbose family IID component
D3Z17_14165	COG3715	PTS system
D3Z17_14170	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_14175	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z17_14180	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D3Z17_14180	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D3Z17_14185	COG1113	amino acid transport
D3Z17_14190	COG1280	lysine exporter protein (LysE YggA)
D3Z17_14195	COG1378	Sugar-specific transcriptional regulator TrmB
D3Z17_14200	COG1595	DNA-templated transcription, initiation
D3Z17_14220	COG2124	cytochrome p450
D3Z17_14220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3Z17_14225	COG1309	transcriptional regulator
D3Z17_14230	COG2226	methyltransferase
D3Z17_14240	COG2116	formate transmembrane transporter activity
D3Z17_14245	COG5609	conserved protein (DUF2294)
D3Z17_14250	COG3383	formate dehydrogenase (NAD+) activity
D3Z17_14255	COG2427	Protein of unknown function (DUF1641)
D3Z17_14265	COG0626	cystathionine gamma-synthase activity
D3Z17_14270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3Z17_14275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D3Z17_14280	COG2226	methyltransferase
D3Z17_14295	COG0768	penicillin binding
D3Z17_14300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D3Z17_14305	COG0572	uridine kinase
D3Z17_14325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D3Z17_14330	COG3906	Belongs to the UPF0473 family
D3Z17_14335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D3Z17_14340	COG4472	Bacterial protein of unknown function (DUF965)
D3Z17_14345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D3Z17_14350	COG0628	permease
D3Z17_14355	COG1126	abc transporter atp-binding protein
D3Z17_14360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z17_14365	COG0765	amino acid transport
D3Z17_14370	COG0765	amino acid transport
D3Z17_14385	COG3881	PFAM PRC-barrel domain
D3Z17_14390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D3Z17_14395	COG0457	Tetratricopeptide repeat
D3Z17_14400	COG0482	sulfurtransferase activity
D3Z17_14405	COG1104	cysteine desulfurase activity
D3Z17_14410	COG1959	2 iron, 2 sulfur cluster binding
D3Z17_14415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D3Z17_14420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D3Z17_14430	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D3Z17_14435	COG0124	histidyl-tRNA synthetase
D3Z17_14445	COG4991	sh3 domain protein
D3Z17_14445	COG3103	Sh3 type 3 domain protein
D3Z17_14445	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z17_14450	COG1490	D-aminoacyl-tRNA deacylase activity
D3Z17_14455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D3Z17_14460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3Z17_14465	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D3Z17_14465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3Z17_14470	COG5416	Lipopolysaccharide assembly protein A domain
D3Z17_14475	COG0490	domain, Protein
D3Z17_14480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3Z17_14480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3Z17_14490	COG2244	polysaccharide biosynthetic process
D3Z17_14495	COG2323	membrane
D3Z17_14505	COG1862	Preprotein translocase
D3Z17_14510	COG0343	queuine tRNA-ribosyltransferase activity
D3Z17_14515	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D3Z17_14525	COG2255	four-way junction helicase activity
D3Z17_14530	COG0632	four-way junction helicase activity
D3Z17_14540	COG2814	Major facilitator Superfamily
D3Z17_14545	COG0673	inositol 2-dehydrogenase activity
D3Z17_14550	COG2112	serine threonine protein kinase
D3Z17_14565	COG1115	amino acid carrier protein
D3Z17_14570	COG0217	transcriptional regulatory protein
D3Z17_14580	COG1388	LysM domain
D3Z17_14585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D3Z17_14590	COG0157	Belongs to the NadC ModD family
D3Z17_14595	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D3Z17_14600	COG1104	cysteine desulfurase activity
D3Z17_14605	COG1827	regulation of RNA biosynthetic process
D3Z17_14610	COG0077	Prephenate dehydratase
D3Z17_14615	COG4492	Belongs to the UPF0735 family
D3Z17_14620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D3Z17_14625	COG3290	protein histidine kinase activity
D3Z17_14630	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D3Z17_14635	COG2868	ribosomal protein
D3Z17_14640	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D3Z17_14645	COG1994	Peptidase M50
D3Z17_14650	COG0739	heme binding
D3Z17_14655	COG2894	cell division
D3Z17_14660	COG0850	regulation of cytokinetic process
D3Z17_14665	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D3Z17_14670	COG1792	Involved in formation and maintenance of cell shape
D3Z17_14675	COG1077	Cell shape determining protein MreB Mrl
D3Z17_14680	COG2003	Belongs to the UPF0758 family
D3Z17_14685	COG0424	maF-like protein
D3Z17_14695	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D3Z17_14700	COG0285	dihydrofolate synthase activity
D3Z17_14705	COG0525	valine-tRNA ligase activity
D3Z17_14715	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3Z17_14720	COG1388	LysM domain
D3Z17_14725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D3Z17_14730	COG0113	porphobilinogen synthase activity
D3Z17_14735	COG1587	Uroporphyrinogen-III synthase
D3Z17_14740	COG0181	hydroxymethylbilane synthase activity
D3Z17_14745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3Z17_14750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D3Z17_14760	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D3Z17_14765	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D3Z17_14770	COG1067	ATP-dependent peptidase activity
D3Z17_14770	COG0470	DNA polymerase III
D3Z17_14775	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D3Z17_14780	COG0544	peptidyl-prolyl cis-trans isomerase activity
D3Z17_14785	COG0457	Tetratricopeptide repeat
D3Z17_14785	COG1477	protein flavinylation
D3Z17_14790	COG0066	3-isopropylmalate dehydratase activity
D3Z17_14795	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D3Z17_14800	COG0473	3-isopropylmalate dehydrogenase activity
D3Z17_14805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D3Z17_14810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D3Z17_14815	COG0440	acetolactate synthase activity
D3Z17_14820	COG0028	Belongs to the TPP enzyme family
D3Z17_14835	COG0454	-acetyltransferase
D3Z17_14840	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D3Z17_14850	COG0622	Phosphoesterase
D3Z17_14855	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D3Z17_14860	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D3Z17_14865	COG5401	PFAM Sporulation and spore germination
D3Z17_14870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D3Z17_14875	COG1846	Transcriptional regulator
D3Z17_14880	COG2197	response regulator
D3Z17_14885	COG0824	Thioesterase
D3Z17_14890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D3Z17_14895	COG1053	succinate dehydrogenase
D3Z17_14900	COG2009	succinate dehydrogenase
D3Z17_14905	COG1719	4-vinyl reductase, 4VR
D3Z17_14910	COG0527	aspartate kinase activity
D3Z17_14920	COG0322	excinuclease ABC activity
D3Z17_14925	COG3118	belongs to the thioredoxin family
D3Z17_14935	COG3534	alpha-L-arabinofuranosidase
D3Z17_14940	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D3Z17_14945	COG2086	electron transfer activity
D3Z17_14950	COG1024	Enoyl-CoA hydratase
D3Z17_14955	COG1309	transcriptional regulator
D3Z17_14960	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z17_14965	COG3766	membrane
D3Z17_14970	COG1193	negative regulation of DNA recombination
D3Z17_14975	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D3Z17_14975	COG1796	DNA polymerase
D3Z17_14980	COG1286	toxin biosynthetic process
D3Z17_14985	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D3Z17_14990	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D3Z17_14995	COG0072	phenylalanine-tRNA ligase activity
D3Z17_14995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3Z17_15000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D3Z17_15010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3Z17_15020	COG3835	regulator
D3Z17_15025	COG0277	FAD linked oxidase domain protein
D3Z17_15030	COG0247	lactate metabolic process
D3Z17_15035	COG0346	lactoylglutathione lyase activity
D3Z17_15045	COG1966	Carbon starvation protein
D3Z17_15050	COG3534	alpha-L-arabinofuranosidase
D3Z17_15055	COG0395	ABC-type sugar transport system, permease component
D3Z17_15060	COG1175	transmembrane transport
D3Z17_15065	COG1653	transport
D3Z17_15070	COG0371	Dehydrogenase
D3Z17_15075	COG0647	UMP catabolic process
D3Z17_15080	COG0235	Class ii aldolase
D3Z17_15085	COG1069	ribulokinase activity
D3Z17_15090	COG2160	L-arabinose isomerase activity
D3Z17_15095	COG3507	Belongs to the glycosyl hydrolase 43 family
D3Z17_15100	COG1363	Peptidase, m42
D3Z17_15110	COG3326	Membrane
D3Z17_15115	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D3Z17_15120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D3Z17_15125	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D3Z17_15135	COG1346	cytolysis
D3Z17_15140	COG1380	Effector of murein hydrolase LrgA
D3Z17_15145	COG3279	Response regulator of the LytR AlgR family
D3Z17_15150	COG3275	phosphorelay sensor kinase activity
D3Z17_15160	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D3Z17_15170	COG0398	Pfam SNARE associated Golgi protein
D3Z17_15175	COG1484	DNA-dependent DNA replication
D3Z17_15180	COG3611	Membrane attachment protein
D3Z17_15185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D3Z17_15190	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D3Z17_15195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3Z17_15200	COG1733	regulation of RNA biosynthetic process
D3Z17_15205	COG2814	Major facilitator Superfamily
D3Z17_15210	COG0656	L-ascorbic acid biosynthetic process
D3Z17_15215	COG0237	dephospho-CoA kinase activity
D3Z17_15220	COG1971	Probably functions as a manganese efflux pump
D3Z17_15225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D3Z17_15230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3Z17_15230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3Z17_15235	COG5002	protein histidine kinase activity
D3Z17_15240	COG0745	RESPONSE REGULATOR receiver
D3Z17_15245	COG0039	L-malate dehydrogenase activity
D3Z17_15250	COG0538	isocitrate dehydrogenase activity
D3Z17_15255	COG0372	Belongs to the citrate synthase family
D3Z17_15260	COG2707	UPF0756 membrane protein
D3Z17_15265	COG0628	permease
D3Z17_15270	COG3030	protein affecting phage T7 exclusion by the F plasmid
D3Z17_15275	COG0469	pyruvate kinase activity
D3Z17_15280	COG0205	6-phosphofructokinase activity
D3Z17_15285	COG0825	malonyl-CoA metabolic process
D3Z17_15290	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D3Z17_15295	COG0281	malic enzyme
D3Z17_15300	COG0587	DNA-directed DNA polymerase activity
D3Z17_15320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D3Z17_15330	COG4109	DRTGG domain
D3Z17_15335	COG0730	response to heat
D3Z17_15340	COG1473	amidohydrolase
D3Z17_15345	COG0196	riboflavin kinase activity
D3Z17_15350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z17_15355	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D3Z17_15360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z17_15365	COG1126	abc transporter atp-binding protein
D3Z17_15370	COG0765	amino acid transport
D3Z17_15375	COG0765	amino acid transport
D3Z17_15380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z17_15385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z17_15390	COG0454	-acetyltransferase
D3Z17_15395	COG0583	DNA-binding transcription factor activity
D3Z17_15400	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D3Z17_15405	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_15415	COG0165	Argininosuccinate lyase
D3Z17_15420	COG0137	argininosuccinate synthase activity
D3Z17_15425	COG0521	Mo-molybdopterin cofactor biosynthetic process
D3Z17_15430	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D3Z17_15440	COG0827	DNA restriction-modification system
D3Z17_15445	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D3Z17_15450	COG3874	Sporulation protein YtfJ
D3Z17_15460	COG1714	RDD family
D3Z17_15465	COG0616	signal peptide processing
D3Z17_15470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D3Z17_15475	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D3Z17_15480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3Z17_15490	COG0301	tRNA thio-modification
D3Z17_15495	COG1104	cysteine desulfurase activity
D3Z17_15500	COG1114	Component of the transport system for branched-chain amino acids
D3Z17_15505	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D3Z17_15510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D3Z17_15515	COG1309	transcriptional regulator
D3Z17_15520	COG1956	GAF domain-containing protein
D3Z17_15525	COG2203	Gaf domain
D3Z17_15525	COG2199	diguanylate cyclase activity
D3Z17_15535	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D3Z17_15540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D3Z17_15550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3Z17_15555	COG0454	-acetyltransferase
D3Z17_15560	COG0517	IMP dehydrogenase activity
D3Z17_15565	COG0123	including yeast histone deacetylase and acetoin utilization protein
D3Z17_15570	COG1360	Flagellar Motor Protein
D3Z17_15575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D3Z17_15580	COG1609	Transcriptional regulator
D3Z17_15585	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D3Z17_15585	COG1605	Chorismate mutase
D3Z17_15590	COG3118	belongs to the thioredoxin family
D3Z17_15595	COG4980	gas vesicle protein
D3Z17_15600	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D3Z17_15605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D3Z17_15610	COG1674	ftsk spoiiie
D3Z17_15615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3Z17_15620	COG4848	Belongs to the UPF0354 family
D3Z17_15625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_15635	COG1363	Peptidase, m42
D3Z17_15640	COG5584	Small secreted protein
D3Z17_15645	COG0281	malic enzyme
D3Z17_15650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z17_15655	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D3Z17_15665	COG0510	thiamine kinase activity
D3Z17_15670	COG1523	belongs to the glycosyl hydrolase 13 family
D3Z17_15675	COG1597	lipid kinase activity
D3Z17_15685	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D3Z17_15690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3Z17_15695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3Z17_15700	COG2252	PERMEase
D3Z17_15705	COG4473	ABC transporter
D3Z17_15710	COG1131	(ABC) transporter
D3Z17_15715	COG1349	DNA-binding transcription factor activity
D3Z17_15720	COG1187	pseudouridine synthase activity
D3Z17_15725	COG2244	polysaccharide biosynthetic process
D3Z17_15730	COG2081	HI0933 family
D3Z17_15735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3Z17_15745	COG5578	integral membrane protein
D3Z17_15750	COG0673	inositol 2-dehydrogenase activity
D3Z17_15755	COG1653	transport
D3Z17_15760	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D3Z17_15765	COG4209	transmembrane transport
D3Z17_15770	COG2207	Transcriptional regulator
D3Z17_15775	COG1653	transport
D3Z17_15780	COG0395	ABC-type sugar transport system, permease component
D3Z17_15785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3Z17_15790	COG2124	cytochrome p450
D3Z17_15795	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D3Z17_15805	COG0156	8-amino-7-oxononanoate synthase activity
D3Z17_15810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3Z17_15820	COG1073	alpha beta
D3Z17_15845	COG1486	melibiose metabolic process
D3Z17_15850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3Z17_15855	COG0495	leucyl-tRNA aminoacylation
D3Z17_15865	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z17_15865	COG2202	Pas domain
D3Z17_15870	COG2814	Major facilitator Superfamily
D3Z17_15875	COG2433	Pfam Transposase IS66
D3Z17_15880	COG0577	efflux transmembrane transporter activity
D3Z17_15885	COG1136	(ABC) transporter
D3Z17_15890	COG2205	protein histidine kinase activity
D3Z17_15895	COG0745	RESPONSE REGULATOR receiver
D3Z17_15900	COG0577	efflux transmembrane transporter activity
D3Z17_15905	COG1136	(ABC) transporter
D3Z17_15920	COG1131	(ABC) transporter
D3Z17_15925	COG1725	Transcriptional regulator
D3Z17_15935	COG1242	4 iron, 4 sulfur cluster binding
D3Z17_15940	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D3Z17_15950	COG2267	carboxylic ester hydrolase activity
D3Z17_15955	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D3Z17_15960	COG1113	amino acid transport
D3Z17_15965	COG0367	asparagine synthase
D3Z17_15970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D3Z17_15975	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D3Z17_15985	COG1506	peptidase
D3Z17_15990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3Z17_15995	COG1116	anion transmembrane transporter activity
D3Z17_16000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3Z17_16005	COG0494	nUDIX hydrolase
D3Z17_16010	COG4824	toxin secretion phage lysis holin
D3Z17_16015	COG0783	Belongs to the Dps family
D3Z17_16030	COG1854	S-ribosylhomocysteine lyase activity
D3Z17_16035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D3Z17_16040	COG0288	reversible hydration of carbon dioxide
D3Z17_16045	COG0254	rRNA binding
D3Z17_16050	COG1271	oxidase subunit
D3Z17_16055	COG1294	oxidase, subunit
D3Z17_16065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3Z17_16070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3Z17_16070	COG1321	iron dependent repressor
D3Z17_16075	COG1121	(ABC) transporter
D3Z17_16080	COG0803	Belongs to the bacterial solute-binding protein 9 family
D3Z17_16085	COG4948	Mandelate Racemase Muconate Lactonizing
D3Z17_16090	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z17_16095	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D3Z17_16100	COG0596	Alpha beta hydrolase
D3Z17_16105	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D3Z17_16110	COG1169	isochorismate synthase
D3Z17_16120	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3Z17_16125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3Z17_16130	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3Z17_16135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3Z17_16140	COG0438	transferase activity, transferring glycosyl groups
D3Z17_16150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3Z17_16155	COG0438	transferase activity, transferring glycosyl groups
D3Z17_16160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3Z17_16165	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D3Z17_16170	COG0058	SHG alpha-glucan phosphorylase activity
D3Z17_16175	COG0297	glycogen (starch) synthase activity
D3Z17_16180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D3Z17_16185	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D3Z17_16190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D3Z17_16305	COG3859	Proton-coupled thiamine transporter YuaJ
D3Z17_16310	COG1247	-acetyltransferase
D3Z17_16315	COG2268	Band 7 protein
D3Z17_16320	COG1585	Membrane protein implicated in regulation of membrane protease activity
D3Z17_16325	COG2318	DinB family
D3Z17_16335	COG1454	alcohol dehydrogenase
D3Z17_16345	COG1510	regulation of RNA biosynthetic process
D3Z17_16355	COG0569	domain protein
D3Z17_16360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3Z17_16365	COG4682	membrane
D3Z17_16370	COG1705	Flagellar rod assembly protein muramidase FlgJ
D3Z17_16375	COG0477	Major facilitator Superfamily
D3Z17_16380	COG5553	Cysteine dioxygenase type I
D3Z17_16390	COG1968	undecaprenyl-diphosphatase activity
D3Z17_16395	COG0628	permease
D3Z17_16400	COG0673	inositol 2-dehydrogenase activity
D3Z17_16405	COG4806	L-rhamnose isomerase
D3Z17_16410	COG3254	rhamnose metabolic process
D3Z17_16415	COG1070	Carbohydrate kinase
D3Z17_16420	COG1349	DNA-binding transcription factor activity
D3Z17_16425	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_16425	COG3347	Dehydrogenase
D3Z17_16435	COG0840	transmembrane signaling receptor activity
D3Z17_16440	COG0840	transmembrane signaling receptor activity
D3Z17_16445	COG0840	transmembrane signaling receptor activity
D3Z17_16450	COG0840	transmembrane signaling receptor activity
D3Z17_16465	COG0432	Pfam Uncharacterised protein family UPF0047
D3Z17_16470	COG0366	Alpha amylase catalytic
D3Z17_16475	COG1253	flavin adenine dinucleotide binding
D3Z17_16480	COG2738	Putative neutral zinc metallopeptidase
D3Z17_16495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3Z17_16510	COG0166	Belongs to the GPI family
D3Z17_16515	COG1979	alcohol dehydrogenase
D3Z17_16520	COG1979	alcohol dehydrogenase
D3Z17_16525	COG2155	Conserved Protein
D3Z17_16530	COG1098	S1 RNA binding domain
D3Z17_16535	COG0436	Aminotransferase
D3Z17_16540	COG1522	sequence-specific DNA binding
D3Z17_16545	COG2267	carboxylic ester hydrolase activity
D3Z17_16555	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D3Z17_16560	COG2205	protein histidine kinase activity
D3Z17_16570	COG5018	Exonuclease
D3Z17_16580	COG2814	Major facilitator Superfamily
D3Z17_16585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3Z17_16590	COG3011	Protein conserved in bacteria
D3Z17_16600	COG3290	protein histidine kinase activity
D3Z17_16605	COG4565	transcriptional regulatory protein
D3Z17_16630	COG3493	citrate carrier protein
D3Z17_16640	COG2111	Na H antiporter
D3Z17_16640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3Z17_16645	COG2111	Na H antiporter
D3Z17_16650	COG1006	Multisubunit Na H antiporter MnhC subunit
D3Z17_16655	COG0651	ATP synthesis coupled electron transport
D3Z17_16660	COG1863	multisubunit Na H antiporter MnhE subunit
D3Z17_16665	COG2212	antiporter activity
D3Z17_16670	COG1320	monovalent cation:proton antiporter activity
D3Z17_16675	COG2050	protein possibly involved in aromatic compounds catabolism
D3Z17_16680	COG2197	response regulator
D3Z17_16685	COG4585	Histidine kinase
D3Z17_16695	COG0142	geranyltranstransferase activity
D3Z17_16710	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D3Z17_16715	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D3Z17_16720	COG1335	isochorismatase
D3Z17_16725	COG5506	Protein of unknown function (DUF1694)
D3Z17_16740	COG0628	permease
D3Z17_16755	COG1418	mRNA catabolic process
D3Z17_16760	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_16770	COG1511	domain protein
D3Z17_16775	COG0433	COG0433 Predicted ATPase
D3Z17_16775	COG1674	ftsk spoiiie
D3Z17_16780	COG4499	WXG100 protein secretion system (Wss), protein YukC
D3Z17_16785	COG5417	Belongs to the EsaB family
D3Z17_16790	COG4842	Belongs to the WXG100 family
D3Z17_16795	COG2508	Transcriptional regulator
D3Z17_16795	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D3Z17_16800	COG0686	Belongs to the AlaDH PNT family
D3Z17_16805	COG5634	Uncharacterized conserved protein (DUF2278)
D3Z17_16810	COG3251	PFAM MbtH domain protein
D3Z17_16815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z17_16820	COG1535	isochorismatase
D3Z17_16820	COG3433	isochorismatase activity
D3Z17_16825	COG1021	2,3-dihydroxybenzoate-AMP ligase
D3Z17_16830	COG1169	isochorismate synthase
D3Z17_16835	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_16840	COG2819	hydrolase of the alpha beta superfamily
D3Z17_16845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D3Z17_16850	COG1268	BioY protein
D3Z17_16855	COG2056	Na+-H+ antiporter family
D3Z17_16860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D3Z17_16865	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D3Z17_16870	COG3584	3D domain protein
D3Z17_16885	COG1252	NADH dehydrogenase
D3Z17_16890	COG0492	ferredoxin-NADP+ reductase activity
D3Z17_16900	COG0516	GMP reductase activity
D3Z17_16905	COG2808	Putative FMN-binding domain
D3Z17_16910	COG0456	acetyltransferase
D3Z17_16915	COG0316	Belongs to the HesB IscA family
D3Z17_16920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D3Z17_16925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3Z17_16930	COG4844	belongs to the
D3Z17_16935	COG1252	NADH dehydrogenase
D3Z17_16940	COG4837	Protein of unknown function (DUF1462)
D3Z17_16945	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D3Z17_16950	COG4946	Tricorn protease homolog
D3Z17_16950	COG1506	peptidase
D3Z17_16950	COG0823	Involved in the tonB-independent uptake of proteins
D3Z17_16955	COG0083	homoserine kinase activity
D3Z17_16960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D3Z17_16965	COG0460	homoserine dehydrogenase
D3Z17_16970	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3Z17_16975	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D3Z17_16980	COG0647	UMP catabolic process
D3Z17_16985	COG2445	Protein of unknown function DUF86
D3Z17_16990	COG4470	Protein conserved in bacteria
D3Z17_17000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D3Z17_17005	COG0739	heme binding
D3Z17_17015	COG3377	Domain of unknown function (DUF1805)
D3Z17_17020	COG0737	Belongs to the 5'-nucleotidase family
D3Z17_17025	COG0730	response to heat
D3Z17_17030	COG1801	Protein of unknown function DUF72
D3Z17_17040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3Z17_17045	COG2508	Transcriptional regulator
D3Z17_17050	COG2233	PERMEase
D3Z17_17055	COG2233	PERMEase
D3Z17_17060	COG3195	allantoin biosynthetic process
D3Z17_17060	COG3648	Uricase
D3Z17_17065	COG2351	hydroxyisourate hydrolase activity
D3Z17_17075	COG2080	2 iron, 2 sulfur cluster binding
D3Z17_17080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D3Z17_17085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D3Z17_17090	COG2068	MobA-Related Protein
D3Z17_17095	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D3Z17_17100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D3Z17_17105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3Z17_17110	COG2356	endonuclease I
D3Z17_17115	COG3842	ATPase activity
D3Z17_17120	COG2188	Transcriptional regulator
D3Z17_17125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3Z17_17130	COG0395	ABC-type sugar transport system, permease component
D3Z17_17135	COG1175	transmembrane transport
D3Z17_17140	COG1653	transport
D3Z17_17145	COG2222	sugar isomerase
D3Z17_17150	COG0322	excinuclease ABC activity
D3Z17_17155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3Z17_17170	COG0346	lactoylglutathione lyase activity
D3Z17_17175	COG0640	Transcriptional regulator
D3Z17_17180	COG0719	Fe-S assembly protein
D3Z17_17185	COG0822	iron-sulfur transferase activity
D3Z17_17190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3Z17_17195	COG0719	Fe-S assembly protein
D3Z17_17200	COG0396	ATPase activity
D3Z17_17215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3Z17_17220	COG1464	Belongs to the NlpA lipoprotein family
D3Z17_17225	COG2011	ABC-type metal ion transport system permease component
D3Z17_17230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D3Z17_17240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z17_17245	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D3Z17_17255	COG0509	glycine decarboxylation via glycine cleavage system
D3Z17_17260	COG1393	Belongs to the ArsC family
D3Z17_17265	COG1960	acyl-CoA dehydrogenase activity
D3Z17_17270	COG0183	Belongs to the thiolase family
D3Z17_17275	COG1024	Enoyl-CoA hydratase
D3Z17_17275	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3Z17_17285	COG0506	proline dehydrogenase activity
D3Z17_17295	COG5577	PFAM Coat F domain
D3Z17_17300	COG1846	Transcriptional regulator
D3Z17_17305	COG0477	Major facilitator Superfamily
D3Z17_17310	COG1942	4-Oxalocrotonate Tautomerase
D3Z17_17320	COG0583	DNA-binding transcription factor activity
D3Z17_17330	COG1120	ATPase activity
D3Z17_17345	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_17350	COG0783	Belongs to the Dps family
D3Z17_17355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3Z17_17360	COG0745	RESPONSE REGULATOR receiver
D3Z17_17365	COG2770	Histidine kinase
D3Z17_17365	COG2205	protein histidine kinase activity
D3Z17_17375	COG1309	transcriptional regulator
D3Z17_17380	COG0114	fumarate hydratase activity
D3Z17_17390	COG0697	spore germination
D3Z17_17395	COG0814	amino acid
D3Z17_17405	COG2197	response regulator
D3Z17_17410	COG4585	Histidine kinase
D3Z17_17415	COG4758	membrane
D3Z17_17420	COG3595	metallopeptidase activity
D3Z17_17425	COG1842	Phage shock protein A
D3Z17_17430	COG4758	membrane
D3Z17_17435	COG2814	Major facilitator Superfamily
D3Z17_17440	COG2096	Adenosyltransferase
D3Z17_17445	COG1120	ATPase activity
D3Z17_17450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z17_17455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z17_17460	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_17465	COG3386	PFAM SMP-30 Gluconolaconase
D3Z17_17470	COG2205	protein histidine kinase activity
D3Z17_17475	COG0745	RESPONSE REGULATOR receiver
D3Z17_17485	COG1191	sigma factor activity
D3Z17_17495	COG2140	Oxalate decarboxylase
D3Z17_17505	COG0577	efflux transmembrane transporter activity
D3Z17_17510	COG1136	(ABC) transporter
D3Z17_17515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3Z17_17520	COG1120	ATPase activity
D3Z17_17525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z17_17530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z17_17535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z17_17545	COG0531	amino acid
D3Z17_17560	COG1988	membrane-bound metal-dependent
D3Z17_17565	COG1368	sulfuric ester hydrolase activity
D3Z17_17570	COG1910	domain protein
D3Z17_17575	COG0725	ABC transporter, periplasmic molybdate-binding protein
D3Z17_17580	COG4149	molybdate abc transporter
D3Z17_17585	COG0656	L-ascorbic acid biosynthetic process
D3Z17_17595	COG0025	NhaP-type Na H and K H
D3Z17_17600	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3Z17_17605	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3Z17_17610	COG3973	AAA domain
D3Z17_17620	COG2860	membrane
D3Z17_17625	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D3Z17_17630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D3Z17_17635	COG2217	Heavy metal translocating P-type atpase
D3Z17_17640	COG2217	Heavy metal translocating P-type atpase
D3Z17_17645	COG2608	mercury ion transmembrane transporter activity
D3Z17_17650	COG1937	Protein conserved in bacteria
D3Z17_17655	COG0673	inositol 2-dehydrogenase activity
D3Z17_17660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D3Z17_17665	COG1289	transmembrane transporter activity
D3Z17_17675	COG2076	Multidrug Resistance protein
D3Z17_17680	COG1309	transcriptional regulator
D3Z17_17685	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_17710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D3Z17_17715	COG0557	exoribonuclease II activity
D3Z17_17720	COG1647	Serine aminopeptidase, S33
D3Z17_17725	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D3Z17_17730	COG0596	Alpha beta hydrolase
D3Z17_17735	COG1476	TRANSCRIPTIONal
D3Z17_17740	COG1396	sequence-specific DNA binding
D3Z17_17745	COG1396	sequence-specific DNA binding
D3Z17_17750	COG1733	regulation of RNA biosynthetic process
D3Z17_17755	COG0840	transmembrane signaling receptor activity
D3Z17_17810	COG1174	glycine betaine transport
D3Z17_17815	COG1732	Glycine betaine
D3Z17_17820	COG1174	glycine betaine transport
D3Z17_17825	COG1125	glycine betaine transport
D3Z17_17825	COG0517	IMP dehydrogenase activity
D3Z17_17830	COG1510	regulation of RNA biosynthetic process
D3Z17_17835	COG1174	glycine betaine transport
D3Z17_17840	COG1732	Glycine betaine
D3Z17_17845	COG1174	glycine betaine transport
D3Z17_17850	COG0517	IMP dehydrogenase activity
D3Z17_17850	COG1125	glycine betaine transport
D3Z17_17855	COG1510	regulation of RNA biosynthetic process
D3Z17_17860	COG2095	MarC family integral membrane protein
D3Z17_17870	COG3064	Membrane
D3Z17_17875	COG4640	response to antibiotic
D3Z17_17880	COG0456	acetyltransferase
D3Z17_17885	COG0148	phosphopyruvate hydratase activity
D3Z17_17890	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D3Z17_17895	COG0149	triose-phosphate isomerase activity
D3Z17_17900	COG0126	phosphoglycerate kinase activity
D3Z17_17905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3Z17_17910	COG2390	Transcriptional regulator
D3Z17_17915	COG2814	Major facilitator Superfamily
D3Z17_17920	COG1609	Transcriptional regulator
D3Z17_17925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z17_17935	COG0583	DNA-binding transcription factor activity
D3Z17_17940	COG0697	spore germination
D3Z17_17945	COG1113	amino acid transport
D3Z17_17950	COG3858	chitin binding
D3Z17_17955	COG1556	Lactate utilization protein
D3Z17_17960	COG1139	Iron-sulfur cluster binding protein
D3Z17_17965	COG0247	lactate metabolic process
D3Z17_17970	COG2197	response regulator
D3Z17_17975	COG4585	Histidine kinase
D3Z17_17980	COG0842	Transport permease protein
D3Z17_17985	COG1131	(ABC) transporter
D3Z17_17990	COG0596	Alpha beta hydrolase
D3Z17_17995	COG2208	phosphoserine phosphatase activity
D3Z17_18000	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D3Z17_18005	COG1874	Beta-galactosidase
D3Z17_18010	COG3833	ABC-type maltose transport systems, permease component
D3Z17_18015	COG1175	transmembrane transport
D3Z17_18020	COG2182	Extracellular solute-binding protein
D3Z17_18025	COG1609	Transcriptional regulator
D3Z17_18030	COG2186	Transcriptional regulator
D3Z17_18035	COG1620	l-lactate permease
D3Z17_18040	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D3Z17_18050	COG5039	Polysaccharide pyruvyl transferase
D3Z17_18055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3Z17_18060	COG0110	maltose O-acetyltransferase activity
D3Z17_18065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D3Z17_18070	COG2244	polysaccharide biosynthetic process
D3Z17_18075	COG1216	Glycosyl transferase, family 2
D3Z17_18080	COG5039	Polysaccharide pyruvyl transferase
D3Z17_18085	COG1216	Glycosyl transferase, family 2
D3Z17_18095	COG0438	transferase activity, transferring glycosyl groups
D3Z17_18100	COG1215	transferase activity, transferring glycosyl groups
D3Z17_18105	COG0438	transferase activity, transferring glycosyl groups
D3Z17_18110	COG1086	Polysaccharide biosynthesis protein
D3Z17_18115	COG0489	protein tyrosine kinase activity
D3Z17_18120	COG3944	biosynthesis protein
D3Z17_18125	COG1396	sequence-specific DNA binding
D3Z17_18130	COG2272	Belongs to the type-B carboxylesterase lipase family
D3Z17_18140	COG3479	Phenolic acid decarboxylase
D3Z17_18150	COG1794	racemase activity, acting on amino acids and derivatives
D3Z17_18155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3Z17_18160	COG1621	beta-fructofuranosidase activity
D3Z17_18165	COG1621	beta-fructofuranosidase activity
D3Z17_18170	COG0531	amino acid
D3Z17_18175	COG1309	transcriptional regulator
D3Z17_18180	COG2076	Multidrug Resistance protein
D3Z17_18185	COG2076	Multidrug Resistance protein
D3Z17_18200	COG0740	serine-type endopeptidase activity
D3Z17_18205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3Z17_18210	COG0366	Alpha amylase catalytic
D3Z17_18215	COG1554	hydrolase, family 65, central catalytic
D3Z17_18220	COG5521	maltodextrose utilization protein MalA
D3Z17_18225	COG3833	ABC-type maltose transport systems, permease component
D3Z17_18230	COG1175	transmembrane transport
D3Z17_18235	COG2182	Extracellular solute-binding protein
D3Z17_18240	COG0366	Alpha amylase catalytic
D3Z17_18245	COG1609	Transcriptional regulator
D3Z17_18250	COG1611	Belongs to the LOG family
D3Z17_18255	COG1694	Mazg nucleotide pyrophosphohydrolase
D3Z17_18260	COG0659	secondary active sulfate transmembrane transporter activity
D3Z17_18265	COG0288	reversible hydration of carbon dioxide
D3Z17_18270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3Z17_18275	COG0577	efflux transmembrane transporter activity
D3Z17_18280	COG1136	(ABC) transporter
D3Z17_18285	COG5002	protein histidine kinase activity
D3Z17_18290	COG0745	RESPONSE REGULATOR receiver
D3Z17_18300	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D3Z17_18305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z17_18310	COG1481	regulation of sporulation
D3Z17_18315	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D3Z17_18320	COG1660	Displays ATPase and GTPase activities
D3Z17_18325	COG1051	belongs to the nudix hydrolase family
D3Z17_18330	COG0492	ferredoxin-NADP+ reductase activity
D3Z17_18335	COG3883	PFAM NLP P60 protein
D3Z17_18335	COG0791	NLP P60 protein
D3Z17_18340	COG0457	Tetratricopeptide repeat
D3Z17_18345	COG1132	(ABC) transporter
D3Z17_18365	COG0140	phosphoribosyl-ATP diphosphatase activity
D3Z17_18365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D3Z17_18370	COG0107	imidazoleglycerol-phosphate synthase activity
D3Z17_18375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D3Z17_18380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D3Z17_18385	COG0131	Imidazoleglycerol-phosphate dehydratase
D3Z17_18390	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D3Z17_18395	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D3Z17_18400	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D3Z17_18405	COG4990	cell redox homeostasis
D3Z17_18410	COG5297	Belongs to the glycosyl hydrolase family 6
D3Z17_18415	COG0110	maltose O-acetyltransferase activity
D3Z17_18420	COG0546	phosphoglycolate phosphatase activity
D3Z17_18425	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D3Z17_18430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D3Z17_18435	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D3Z17_18440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D3Z17_18445	COG0363	glucosamine-6-phosphate deaminase activity
D3Z17_18455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3Z17_18460	COG1846	Transcriptional regulator
D3Z17_18475	COG1846	Transcriptional regulator
D3Z17_18480	COG2814	Major facilitator Superfamily
D3Z17_18485	COG1950	PFAM Membrane protein of
D3Z17_18490	COG1983	PspC domain protein
D3Z17_18495	COG3595	metallopeptidase activity
D3Z17_18515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D3Z17_18520	COG0556	nucleotide-excision repair
D3Z17_18525	COG4897	Protein conserved in bacteria
D3Z17_18530	COG0574	Belongs to the PEP-utilizing enzyme family
D3Z17_18530	COG3848	Pyruvate phosphate dikinase
D3Z17_18535	COG1309	transcriptional regulator
D3Z17_18540	COG2814	Major facilitator Superfamily
D3Z17_18545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3Z17_18555	COG3409	Peptidoglycan-binding domain 1 protein
D3Z17_18555	COG0793	Belongs to the peptidase S41A family
D3Z17_18560	COG2177	Part of the ABC transporter FtsEX involved in
D3Z17_18565	COG2884	Cell division ATP-binding protein ftsE
D3Z17_18570	COG2010	Cytochrome c
D3Z17_18575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z17_18585	COG0653	protein targeting
D3Z17_18590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D3Z17_18605	COG1516	flagellar protein fliS
D3Z17_18610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D3Z17_18615	COG1334	flagellar protein FlaG
D3Z17_18620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3Z17_18625	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D3Z17_18630	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D3Z17_18640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3Z17_18645	COG4786	Flagellar basal body rod
D3Z17_18645	COG1256	bacterial-type flagellum assembly
D3Z17_18650	COG3418	PFAM FlgN family protein
D3Z17_18655	COG2747	anti-sigma28 factor FlgM
D3Z17_18665	COG1040	competence protein
D3Z17_18675	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D3Z17_18680	COG1307	EDD domain protein, DegV family
D3Z17_18685	COG2197	response regulator
D3Z17_18690	COG4585	Histidine kinase
D3Z17_18695	COG1739	Uncharacterized protein family UPF0029
D3Z17_18700	COG1316	TRANSCRIPTIONal
D3Z17_18705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3Z17_18710	COG0438	transferase activity, transferring glycosyl groups
D3Z17_18715	COG1215	transferase activity, transferring glycosyl groups
D3Z17_18720	COG3206	protein involved in exopolysaccharide biosynthesis
D3Z17_18725	COG3307	-O-antigen
D3Z17_18730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3Z17_18735	COG0438	transferase activity, transferring glycosyl groups
D3Z17_18735	COG0297	glycogen (starch) synthase activity
D3Z17_18740	COG2244	polysaccharide biosynthetic process
D3Z17_18755	COG2247	cell wall binding repeat
D3Z17_18755	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z17_18760	COG2247	cell wall binding repeat
D3Z17_18760	COG2385	sporulation resulting in formation of a cellular spore
D3Z17_18770	COG1316	TRANSCRIPTIONal
D3Z17_18775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D3Z17_18795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3Z17_18800	COG1134	teichoic acid transport
D3Z17_18805	COG1682	transport, permease protein
D3Z17_18810	COG1215	transferase activity, transferring glycosyl groups
D3Z17_18810	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3Z17_18815	COG0463	Glycosyl transferase, family 2
D3Z17_18860	COG4193	domain, Protein
D3Z17_18865	COG1482	cell wall glycoprotein biosynthetic process
D3Z17_18870	COG0697	spore germination
D3Z17_18875	COG0814	amino acid
D3Z17_18885	COG2814	Major facilitator Superfamily
D3Z17_18890	COG1316	TRANSCRIPTIONal
D3Z17_18895	COG0561	phosphatase activity
D3Z17_18900	COG0791	NLP P60 protein
D3Z17_18910	COG2843	Capsule synthesis protein
D3Z17_18920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D3Z17_18925	COG1609	Transcriptional regulator
D3Z17_18930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3Z17_18935	COG1869	D-ribose catabolic process
D3Z17_18940	COG1129	ABC transporter
D3Z17_18945	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3Z17_18950	COG1879	ABC-type sugar transport system periplasmic component
D3Z17_18955	COG3103	Sh3 type 3 domain protein
D3Z17_18965	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3Z17_18970	COG3527	Alpha-acetolactate decarboxylase
D3Z17_18975	COG0028	Belongs to the TPP enzyme family
D3Z17_18985	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3Z17_19000	COG5337	Spore coat protein CotH
D3Z17_19010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3Z17_19020	COG0405	Gamma-glutamyltransferase
D3Z17_19025	COG1522	sequence-specific DNA binding
D3Z17_19030	COG2059	Chromate
D3Z17_19035	COG2059	Chromate
D3Z17_19050	COG5444	nuclease activity
D3Z17_19065	COG3878	Protein conserved in bacteria
D3Z17_19070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3Z17_19075	COG4464	protein tyrosine phosphatase activity
D3Z17_19080	COG0489	protein tyrosine kinase activity
D3Z17_19085	COG3944	biosynthesis protein
D3Z17_19095	COG4715	Zinc finger, swim domain protein
D3Z17_19100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D3Z17_19110	COG0561	phosphatase activity
D3Z17_19115	COG1349	DNA-binding transcription factor activity
D3Z17_19120	COG0629	single-stranded DNA binding
D3Z17_19135	COG3764	Sortase (surface protein transpeptidase)
D3Z17_19145	COG3279	Response regulator of the LytR AlgR family
D3Z17_19150	COG2972	Histidine kinase
D3Z17_19150	COG0745	RESPONSE REGULATOR receiver
D3Z17_19155	COG1970	mechanosensitive ion channel activity
D3Z17_19160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D3Z17_19165	COG0457	Tetratricopeptide repeat
D3Z17_19170	COG4786	Flagellar basal body rod
D3Z17_19175	COG4786	Flagellar basal body rod
D3Z17_19180	COG1077	Cell shape determining protein MreB Mrl
D3Z17_19185	COG1609	Transcriptional regulator
D3Z17_19195	COG1846	Transcriptional regulator
D3Z17_19200	COG2814	Major facilitator Superfamily
D3Z17_19205	COG3420	alginic acid biosynthetic process
D3Z17_19210	COG1953	Uracil, thiamine, allantoin
D3Z17_19215	COG0477	Major facilitator Superfamily
D3Z17_19220	COG1335	isochorismatase
D3Z17_19230	COG0004	ammonium transporteR
D3Z17_19235	COG0347	Belongs to the P(II) protein family
D3Z17_19240	COG0671	phosphoesterase, PA-phosphatase related
D3Z17_19250	COG0739	heme binding
D3Z17_19255	COG1247	-acetyltransferase
D3Z17_19270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3Z17_19275	COG0789	Transcriptional regulator
D3Z17_19285	COG2910	NAD(P)H-binding
D3Z17_19290	COG1959	2 iron, 2 sulfur cluster binding
D3Z17_19295	COG0804	urea catabolic process
D3Z17_19300	COG0832	Belongs to the urease beta subunit family
D3Z17_19305	COG0831	urea catabolic process
D3Z17_19320	COG3237	CsbD-like
D3Z17_19325	COG1994	Peptidase M50
D3Z17_19330	COG0457	Tetratricopeptide repeat
D3Z17_19340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D3Z17_19345	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D3Z17_19355	COG2304	oxidoreductase activity
D3Z17_19365	COG2304	oxidoreductase activity
D3Z17_19370	COG2385	sporulation resulting in formation of a cellular spore
D3Z17_19375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D3Z17_19385	COG4836	Membrane
D3Z17_19395	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D3Z17_19400	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D3Z17_19405	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D3Z17_19410	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D3Z17_19415	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D3Z17_19420	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D3Z17_19425	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D3Z17_19430	COG0356	it plays a direct role in the translocation of protons across the membrane
D3Z17_19440	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D3Z17_19445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D3Z17_19450	COG4475	Protein of unknown function (DUF436)
D3Z17_19455	COG0698	ribose 5-phosphate isomerase
D3Z17_19460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3Z17_19465	COG1971	Probably functions as a manganese efflux pump
D3Z17_19470	COG0009	L-threonylcarbamoyladenylate synthase
D3Z17_19475	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D3Z17_19495	COG2890	protein-(glutamine-N5) methyltransferase activity
D3Z17_19500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D3Z17_19505	COG0346	lactoylglutathione lyase activity
D3Z17_19510	COG0789	Transcriptional regulator
D3Z17_19515	COG0679	Auxin Efflux Carrier
D3Z17_19520	COG0281	malic enzyme
D3Z17_19525	COG1435	thymidine kinase activity
D3Z17_19530	COG0254	rRNA binding
D3Z17_19535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D3Z17_19540	COG1494	fructose-1,6-bisphosphatase
D3Z17_19550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D3Z17_19555	COG0191	fructose-bisphosphate aldolase activity
D3Z17_19560	COG2204	response regulator
D3Z17_19565	COG4821	SIS domain
D3Z17_19570	COG0504	CTP synthase activity
D3Z17_19575	COG3343	RNA polymerase activity
D3Z17_19580	COG1960	acyl-CoA dehydrogenase activity
D3Z17_19585	COG0247	lactate metabolic process
D3Z17_19585	COG2181	nitrate reductase activity
D3Z17_19590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3Z17_19595	COG4294	response to UV
D3Z17_19605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3Z17_19610	COG1132	(ABC) transporter
D3Z17_19615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3Z17_19625	COG2181	nitrate reductase activity
D3Z17_19630	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D3Z17_19635	COG1140	nitrate reductase beta subunit
D3Z17_19640	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D3Z17_19645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3Z17_19655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3Z17_19660	COG2223	nitrite transmembrane transporter activity
D3Z17_19665	COG0018	arginyl-trna synthetase
D3Z17_19670	COG4506	Protein conserved in bacteria
D3Z17_19685	COG0535	radical SAM domain protein
D3Z17_19695	COG1131	(ABC) transporter
D3Z17_19700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D3Z17_19705	COG0612	Peptidase, M16
D3Z17_19710	COG0612	Peptidase, M16
D3Z17_19720	COG3391	amine dehydrogenase activity
D3Z17_19725	COG3391	amine dehydrogenase activity
D3Z17_19735	COG0457	Tetratricopeptide repeat
D3Z17_19765	COG1131	(ABC) transporter
D3Z17_19775	COG0010	Belongs to the arginase family
D3Z17_19780	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D3Z17_19785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3Z17_19800	COG1994	Peptidase M50
D3Z17_19805	COG1942	4-Oxalocrotonate Tautomerase
D3Z17_19810	COG1846	Transcriptional regulator
D3Z17_19815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D3Z17_19820	COG0477	Major facilitator Superfamily
D3Z17_19825	COG1959	2 iron, 2 sulfur cluster binding
D3Z17_19830	COG3465	dGTPase activity
D3Z17_19835	COG1078	dGTPase activity
D3Z17_19840	COG4844	belongs to the
D3Z17_19850	COG0697	spore germination
D3Z17_19855	COG0095	Lipoate-protein ligase
D3Z17_19860	COG0583	DNA-binding transcription factor activity
D3Z17_19865	COG0280	phosphate acetyltransferase
D3Z17_19875	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_19880	COG0436	Aminotransferase
D3Z17_19885	COG2814	Major facilitator Superfamily
D3Z17_19890	COG0151	Belongs to the GarS family
D3Z17_19895	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_19900	COG1917	Cupin 2, conserved barrel domain protein
D3Z17_19905	COG0077	Prephenate dehydratase
D3Z17_19910	COG2814	Major facilitator Superfamily
D3Z17_19915	COG0833	amino acid
D3Z17_19920	COG4187	Peptidase family M20/M25/M40
D3Z17_19925	COG1012	belongs to the aldehyde dehydrogenase family
D3Z17_19930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3Z17_19940	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D3Z17_19945	COG1091	dTDP-4-dehydrorhamnose reductase activity
D3Z17_19950	COG1088	dTDP-glucose 4,6-dehydratase activity
D3Z17_19955	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D3Z17_19960	COG3980	spore coat polysaccharide biosynthesis protein
D3Z17_19965	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D3Z17_19970	COG2089	acid synthase
D3Z17_19975	COG0456	acetyltransferase
D3Z17_19980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3Z17_19985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3Z17_19990	COG0463	Glycosyl transferase, family 2
D3Z17_20005	COG2363	Small membrane protein
D3Z17_20010	COG2233	PERMEase
D3Z17_20020	COG1012	belongs to the aldehyde dehydrogenase family
D3Z17_20025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D3Z17_20030	COG1216	Glycosyl transferase, family 2
D3Z17_20045	COG1695	Transcriptional regulator
D3Z17_20050	COG0351	phosphomethylpyrimidine kinase
D3Z17_20060	COG1621	beta-fructofuranosidase activity
D3Z17_20065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_20065	COG1263	PTS System
D3Z17_20070	COG2116	formate transmembrane transporter activity
D3Z17_20075	COG3711	transcriptional antiterminator
D3Z17_20085	COG1404	Belongs to the peptidase S8 family
D3Z17_20090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z17_20095	COG0778	Nitroreductase
D3Z17_20100	COG0772	Belongs to the SEDS family
D3Z17_20110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D3Z17_20115	COG1845	cytochrome c oxidase, subunit III
D3Z17_20120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3Z17_20125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3Z17_20130	COG2261	transglycosylase associated protein
D3Z17_20135	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D3Z17_20140	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D3Z17_20145	COG2246	polysaccharide biosynthetic process
D3Z17_20150	COG1309	transcriptional regulator
D3Z17_20160	COG3162	membrane
D3Z17_20165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3Z17_20170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D3Z17_20175	COG2837	iron assimilation
D3Z17_20180	COG2822	iron ion transport
D3Z17_20185	COG0672	)-iron permease
D3Z17_20190	COG0352	thiamine-phosphate diphosphorylase activity
D3Z17_20195	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D3Z17_20200	COG0583	DNA-binding transcription factor activity
D3Z17_20205	COG1380	Effector of murein hydrolase LrgA
D3Z17_20210	COG1346	cytolysis
D3Z17_20215	COG2814	Major facilitator Superfamily
D3Z17_20220	COG4895	conserved protein (DUF2196)
D3Z17_20225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D3Z17_20230	COG0346	lactoylglutathione lyase activity
D3Z17_20235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3Z17_20240	COG1404	Belongs to the peptidase S8 family
D3Z17_20245	COG1263	PTS System
D3Z17_20245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_20250	COG3711	transcriptional antiterminator
D3Z17_20255	COG1442	glycosyl transferase family 8
D3Z17_20260	COG5522	Integral membrane protein (intg_mem_TP0381)
D3Z17_20265	COG1846	Transcriptional regulator
D3Z17_20270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D3Z17_20275	COG2234	aminopeptidase activity
D3Z17_20290	COG2814	Major facilitator Superfamily
D3Z17_20295	COG2357	RelA SpoT domain protein
D3Z17_20300	COG1575	Belongs to the MenA family. Type 1 subfamily
D3Z17_20315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z17_20320	COG1696	Membrane protein involved in D-alanine export
D3Z17_20325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z17_20330	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D3Z17_20335	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D3Z17_20340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3Z17_20345	COG1486	melibiose metabolic process
D3Z17_20350	COG1447	Phosphotransferase system cellobiose-specific component IIA
D3Z17_20355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3Z17_20360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3Z17_20365	COG3711	transcriptional antiterminator
D3Z17_20365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z17_20375	COG2094	Belongs to the DNA glycosylase MPG family
D3Z17_20380	COG0753	catalase activity
D3Z17_20385	COG2814	Major facilitator Superfamily
D3Z17_20390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D3Z17_20395	COG1131	(ABC) transporter
D3Z17_20415	COG1595	DNA-templated transcription, initiation
D3Z17_20420	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D3Z17_20425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D3Z17_20430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D3Z17_20435	COG4988	ABC transporter
D3Z17_20440	COG1294	oxidase, subunit
D3Z17_20445	COG1271	oxidase subunit
D3Z17_20450	COG3493	citrate carrier protein
D3Z17_20455	COG0501	Belongs to the peptidase M48B family
D3Z17_20465	COG0726	polysaccharide deacetylase
D3Z17_20470	COG3842	ATPase activity
D3Z17_20475	COG2508	Transcriptional regulator
D3Z17_20480	COG1012	belongs to the aldehyde dehydrogenase family
D3Z17_20485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z17_20500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D3Z17_20505	COG1881	PFAM PEBP family protein
D3Z17_20510	COG0583	DNA-binding transcription factor activity
D3Z17_20520	COG4585	Histidine kinase
D3Z17_20525	COG2197	response regulator
D3Z17_20530	COG2195	Cleaves the N-terminal amino acid of tripeptides
D3Z17_20540	COG4894	glucomannan catabolic process
D3Z17_20545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D3Z17_20550	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D3Z17_20555	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_20560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D3Z17_20565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D3Z17_20570	COG2610	gluconate transmembrane transporter activity
D3Z17_20575	COG0500	methyltransferase
D3Z17_20580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3Z17_20595	COG0693	protein deglycase activity
D3Z17_20595	COG0753	catalase activity
D3Z17_20600	COG2851	Citrate transporter
D3Z17_20605	COG2273	Hydrolase Family 16
D3Z17_20610	COG3711	transcriptional antiterminator
D3Z17_20620	COG2270	Major facilitator Superfamily
D3Z17_20625	COG0513	Belongs to the DEAD box helicase family
D3Z17_20630	COG2755	lipolytic protein G-D-S-L family
D3Z17_20630	COG3401	FG-GAP repeat protein
D3Z17_20675	COG3209	COG3209 Rhs family protein
D3Z17_20680	COG0697	spore germination
D3Z17_20685	COG0589	response to stress
D3Z17_20690	COG2723	6-phospho-beta-galactosidase activity
D3Z17_20695	COG2190	(PTS) system
D3Z17_20695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_20695	COG1263	PTS System
D3Z17_20740	COG3507	Belongs to the glycosyl hydrolase 43 family
D3Z17_20755	COG2986	histidine ammonia-lyase
D3Z17_20760	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D3Z17_20765	COG1228	amidohydrolase
D3Z17_20770	COG0010	Belongs to the arginase family
D3Z17_20775	COG0833	amino acid
D3Z17_20780	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D3Z17_20785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3Z17_20790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D3Z17_20795	COG2390	Transcriptional regulator
D3Z17_20805	COG3192	ethanolamine utilization protein
D3Z17_20810	COG2079	MmgE PrpD family protein
D3Z17_20820	COG1126	abc transporter atp-binding protein
D3Z17_20825	COG0765	amino acid transport
D3Z17_20830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z17_20845	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D3Z17_20850	COG0561	phosphatase activity
D3Z17_20880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z17_20885	COG5294	Protein conserved in bacteria
D3Z17_20890	COG0577	efflux transmembrane transporter activity
D3Z17_20895	COG1136	(ABC) transporter
D3Z17_20900	COG2205	protein histidine kinase activity
D3Z17_20905	COG0745	RESPONSE REGULATOR receiver
D3Z17_20910	COG0191	fructose-bisphosphate aldolase activity
D3Z17_20915	COG1082	Xylose isomerase domain protein TIM barrel
D3Z17_20920	COG1082	Xylose isomerase domain protein TIM barrel
D3Z17_20925	COG0673	inositol 2-dehydrogenase activity
D3Z17_20930	COG2814	Major facilitator Superfamily
D3Z17_20935	COG1082	Xylose isomerase domain protein TIM barrel
D3Z17_20940	COG3962	Belongs to the TPP enzyme family
D3Z17_20945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3Z17_20950	COG3718	enzyme involved in inositol metabolism
D3Z17_20955	COG1012	belongs to the aldehyde dehydrogenase family
D3Z17_20960	COG1349	DNA-binding transcription factor activity
D3Z17_20965	COG0667	Aldo Keto reductase
D3Z17_20980	COG2814	Major facilitator Superfamily
D3Z17_20985	COG0326	Molecular chaperone. Has ATPase activity
D3Z17_20995	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_21000	COG1309	transcriptional regulator
D3Z17_21005	COG1012	belongs to the aldehyde dehydrogenase family
D3Z17_21015	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3Z17_21025	COG1714	RDD family
D3Z17_21030	COG2311	Membrane
D3Z17_21035	COG1917	Cupin 2, conserved barrel domain protein
D3Z17_21040	COG1309	transcriptional regulator
D3Z17_21045	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z17_21050	COG1846	Transcriptional regulator
D3Z17_21055	COG1380	Effector of murein hydrolase LrgA
D3Z17_21060	COG1346	cytolysis
D3Z17_21065	COG5039	Polysaccharide pyruvyl transferase
D3Z17_21070	COG1929	Belongs to the glycerate kinase type-1 family
D3Z17_21075	COG1802	Transcriptional regulator
D3Z17_21080	COG1070	Carbohydrate kinase
D3Z17_21085	COG2610	gluconate transmembrane transporter activity
D3Z17_21090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D3Z17_21095	COG0450	alkyl hydroperoxide reductase
D3Z17_21100	COG3634	alkyl hydroperoxide reductase activity
D3Z17_21110	COG2723	6-phospho-beta-galactosidase activity
D3Z17_21115	COG2190	(PTS) system
D3Z17_21120	COG2190	(PTS) system
D3Z17_21120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z17_21120	COG1263	PTS System
D3Z17_21125	COG2188	Transcriptional regulator
D3Z17_21140	COG1131	(ABC) transporter
D3Z17_21145	COG1994	Peptidase M50
D3Z17_21150	COG0535	radical SAM domain protein
D3Z17_21160	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D3Z17_21170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D3Z17_21185	COG1063	alcohol dehydrogenase
D3Z17_21205	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D3Z17_21210	COG0456	acetyltransferase
D3Z17_21215	COG0457	Tetratricopeptide repeat
D3Z17_21225	COG0010	Belongs to the arginase family
D3Z17_21230	COG0833	amino acid
D3Z17_21235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3Z17_21240	COG3829	transcription factor binding
D3Z17_21250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3Z17_21255	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D3Z17_21260	COG4853	Protein conserved in bacteria
D3Z17_21265	COG4863	YycH protein
D3Z17_21270	COG5002	protein histidine kinase activity
D3Z17_21275	COG0745	RESPONSE REGULATOR receiver
D3Z17_21305	COG0346	lactoylglutathione lyase activity
D3Z17_21310	COG0305	Participates in initiation and elongation during chromosome replication
D3Z17_21325	COG3093	addiction module antidote protein HigA
D3Z17_21330	COG2807	transmembrane transport
D3Z17_21335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D3Z17_21340	COG0359	binds to the 23S rRNA
D3Z17_21345	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D3Z17_21350	COG4241	membrane
D3Z17_21360	COG5577	PFAM Coat F domain
D3Z17_21365	COG1733	regulation of RNA biosynthetic process
D3Z17_21370	COG1227	inorganic diphosphatase activity
D3Z17_21385	COG2271	Major facilitator Superfamily
D3Z17_21390	COG0789	Transcriptional regulator
D3Z17_21390	COG4978	Transcriptional regulator
D3Z17_21400	COG4319	ketosteroid isomerase
D3Z17_21410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z17_21415	COG1846	Transcriptional regulator
D3Z17_21420	COG2153	protein acetylation
D3Z17_21425	COG2364	Membrane
D3Z17_21430	COG0456	acetyltransferase
D3Z17_21435	COG2315	Protein conserved in bacteria
D3Z17_21440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3Z17_21460	COG0789	Transcriptional regulator
D3Z17_21465	COG0697	spore germination
D3Z17_21470	COG1331	Highly conserved protein containing a thioredoxin domain
D3Z17_21475	COG1266	CAAX protease self-immunity
D3Z17_21480	COG2814	Major facilitator Superfamily
D3Z17_21480	COG0477	Major facilitator Superfamily
D3Z17_21485	COG0110	maltose O-acetyltransferase activity
D3Z17_21490	COG0346	lactoylglutathione lyase activity
D3Z17_21495	COG1609	Transcriptional regulator
D3Z17_21500	COG0708	Exodeoxyribonuclease III
D3Z17_21505	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D3Z17_21510	COG0629	single-stranded DNA binding
D3Z17_21515	COG0360	Binds together with S18 to 16S ribosomal RNA
D3Z17_21520	COG0012	GTP binding
D3Z17_21525	COG0243	molybdopterin cofactor binding
D3Z17_21530	COG4481	Protein conserved in bacteria
D3Z17_21535	COG3949	Membrane
D3Z17_21545	COG1475	DNA binding
D3Z17_21550	COG1192	Involved in chromosome partitioning
D3Z17_21560	COG1475	DNA binding
D3Z17_21565	COG0357	Ribosomal RNA small subunit methyltransferase G
D3Z17_21570	COG0445	tRNA wobble uridine modification
D3Z17_21575	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D3Z17_21580	COG1847	R3H domain protein
D3Z17_21585	COG0706	membrane insertase activity
D3Z17_21590	COG0594	ribonuclease P activity
D3Z17_21595	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D3Z17_21600	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D3Z17_21605	COG0592	DNA-directed DNA polymerase activity
D3Z17_21610	COG2501	S4 domain
D3Z17_21615	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D3Z17_21625	COG0187	DNA topoisomerase II activity
D3Z17_21630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3Z17_21640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity