locus-tag	class	description
GII85_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII85_00010	COG0592	DNA-directed DNA polymerase activity
GII85_00015	COG2501	S4 domain
GII85_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII85_00030	COG0187	DNA topoisomerase II activity
GII85_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII85_00070	COG0516	GMP reductase activity
GII85_00070	COG0517	IMP dehydrogenase activity
GII85_00075	COG1686	Belongs to the peptidase S11 family
GII85_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII85_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII85_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII85_00100	COG1428	Deoxynucleoside kinase
GII85_00105	COG1428	Deoxynucleoside kinase
GII85_00110	COG1388	LysM domain
GII85_00110	COG3858	chitin binding
GII85_00115	COG1335	isochorismatase
GII85_00120	COG0590	tRNA wobble adenosine to inosine editing
GII85_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII85_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII85_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII85_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII85_00190	COG3853	Toxic anion resistance protein (TelA)
GII85_00195	COG1982	Orn Lys Arg decarboxylase major
GII85_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII85_00205	COG3870	Protein conserved in bacteria
GII85_00210	COG1728	Protein conserved in bacteria
GII85_00215	COG0470	DNA polymerase III
GII85_00220	COG1774	PSP1 C-terminal conserved region
GII85_00225	COG4467	Involved in initiation control of chromosome replication
GII85_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII85_00235	COG2827	Endonuclease containing a URI domain
GII85_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII85_00245	COG2002	toxin-antitoxin pair type II binding
GII85_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII85_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII85_00255	COG0084	hydrolase, TatD family'
GII85_00260	COG3584	3D domain protein
GII85_00260	COG3583	domain protein
GII85_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII85_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII85_00280	COG4466	Protein conserved in bacteria
GII85_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII85_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII85_00300	COG0251	oxidation-reduction process
GII85_00305	COG2088	sporulation resulting in formation of a cellular spore
GII85_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII85_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII85_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII85_00325	COG0193	aminoacyl-tRNA hydrolase activity
GII85_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII85_00340	COG2002	toxin-antitoxin pair type II binding
GII85_00345	COG2244	polysaccharide biosynthetic process
GII85_00350	COG3956	TIGRFAM MazG family protein
GII85_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII85_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII85_00375	COG1098	S1 RNA binding domain
GII85_00390	COG2208	phosphoserine phosphatase activity
GII85_00395	COG2304	oxidoreductase activity
GII85_00400	COG0515	serine threonine protein kinase
GII85_00405	COG0037	tRNA processing
GII85_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII85_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII85_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII85_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII85_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII85_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII85_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII85_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII85_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII85_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII85_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII85_00470	COG1396	sequence-specific DNA binding
GII85_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII85_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII85_00560	COG4463	regulation of RNA biosynthetic process
GII85_00565	COG3880	PFAM UvrB UvrC protein
GII85_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII85_00575	COG0542	response to heat
GII85_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII85_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII85_00590	COG4956	integral membrane protein (PIN domain superfamily)
GII85_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII85_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII85_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII85_00610	COG1045	serine acetyltransferase
GII85_00615	COG0215	cysteine-tRNA ligase activity
GII85_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII85_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII85_00630	COG3688	RNA-binding protein containing a PIN domain
GII85_00635	COG1595	DNA-templated transcription, initiation
GII85_00640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII85_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII85_00650	COG0250	Participates in transcription elongation, termination and antitermination
GII85_00655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GII85_00660	COG0081	regulation of translation
GII85_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII85_00670	COG0222	ribosome binding
GII85_00675	COG2813	Specifically methylates the guanine in position
GII85_00680	COG0085	RNA polymerase activity
GII85_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII85_00690	COG1358	cellular component organization or biogenesis
GII85_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII85_00700	COG0049	tRNA binding
GII85_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII85_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII85_00715	COG0596	Alpha beta hydrolase
GII85_00720	COG0051	transcription antitermination factor activity, RNA binding
GII85_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII85_00730	COG0088	Forms part of the polypeptide exit tunnel
GII85_00735	COG0089	rRNA binding
GII85_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII85_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GII85_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GII85_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GII85_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII85_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
GII85_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII85_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII85_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII85_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII85_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII85_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII85_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII85_00815	COG1841	ribosomal large subunit assembly
GII85_00820	COG0200	Binds to the 23S rRNA
GII85_00825	COG0201	protein transport
GII85_00830	COG0563	adenylate kinase activity
GII85_00835	COG0024	Methionine aminopeptidase
GII85_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII85_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GII85_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII85_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII85_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII85_00865	COG0202	RNA polymerase activity
GII85_00870	COG0203	ribosomal protein L17
GII85_00875	COG1122	ATPase activity
GII85_00880	COG1122	ATPase activity
GII85_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII85_00890	COG0101	tRNA pseudouridine synthase activity
GII85_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII85_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII85_00905	COG2226	methyltransferase
GII85_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII85_00920	COG0489	protein tyrosine kinase activity
GII85_00930	COG2194	sulfuric ester hydrolase activity
GII85_00935	COG0726	polysaccharide deacetylase
GII85_01020	COG0659	secondary active sulfate transmembrane transporter activity
GII85_01025	COG0385	Bile acid
GII85_01030	COG2819	hydrolase of the alpha beta superfamily
GII85_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII85_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII85_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII85_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII85_01050	COG2207	Transcriptional regulator
GII85_01055	COG3876	Protein conserved in bacteria
GII85_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
GII85_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII85_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII85_01070	COG1263	PTS System
GII85_01075	COG1737	Transcriptional regulator
GII85_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII85_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII85_01090	COG1683	Conserved Protein
GII85_01120	COG1595	DNA-templated transcription, initiation
GII85_01125	COG5662	AntiSigma factor
GII85_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII85_01135	COG4856	YbbR-like protein
GII85_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII85_01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII85_01160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII85_01165	COG2169	Transcriptional regulator
GII85_01170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII85_01175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII85_01180	COG3002	Belongs to the UPF0753 family
GII85_01185	COG0288	reversible hydration of carbon dioxide
GII85_01195	COG5609	conserved protein (DUF2294)
GII85_01200	COG0640	Transcriptional regulator
GII85_01205	COG2814	Major facilitator Superfamily
GII85_01220	COG0515	serine threonine protein kinase
GII85_01235	COG1113	amino acid transport
GII85_01250	COG2602	Beta-lactamase
GII85_01255	COG2124	cytochrome p450
GII85_01265	COG0531	amino acid
GII85_01270	COG0584	glycerophosphoryl diester phosphodiesterase
GII85_01275	COG2271	Major facilitator Superfamily
GII85_01285	COG0456	acetyltransferase
GII85_01285	COG1846	Transcriptional regulator
GII85_01290	COG2271	Major facilitator Superfamily
GII85_01300	COG3409	Peptidoglycan-binding domain 1 protein
GII85_01305	COG0697	spore germination
GII85_01310	COG2207	Transcriptional regulator
GII85_01310	COG1917	Cupin 2, conserved barrel domain protein
GII85_01315	COG1397	ADP-ribosylglycohydrolase
GII85_01320	COG5444	nuclease activity
GII85_01325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII85_01330	COG3591	Belongs to the peptidase S1B family
GII85_01340	COG0596	Alpha beta hydrolase
GII85_01345	COG1183	phosphatidylcholine synthase activity
GII85_01350	COG0586	Pfam SNARE associated Golgi protein
GII85_01355	COG0688	phosphatidylethanolamine metabolic process
GII85_01365	COG2312	Erythromycin esterase
GII85_01375	COG1301	dicarboxylic acid transport
GII85_01380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII85_01380	COG2190	(PTS) system
GII85_01380	COG1263	PTS System
GII85_01385	COG0363	glucosamine-6-phosphate deaminase activity
GII85_01400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII85_01405	COG0833	amino acid
GII85_01410	COG2040	homocysteine
GII85_01420	COG1115	amino acid carrier protein
GII85_01425	COG2066	Belongs to the glutaminase family
GII85_01430	COG4191	Histidine kinase
GII85_01435	COG0784	Response regulator, receiver
GII85_01440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII85_01445	COG1012	belongs to the aldehyde dehydrogenase family
GII85_01450	COG2271	Major facilitator Superfamily
GII85_01455	COG4948	Mandelate Racemase Muconate Lactonizing
GII85_01460	COG2186	Transcriptional regulator
GII85_01465	COG2721	sulfolactate sulfo-lyase activity
GII85_01470	COG3173	Aminoglycoside phosphotransferase
GII85_01480	COG0697	spore germination
GII85_01485	COG0745	RESPONSE REGULATOR receiver
GII85_01490	COG2205	protein histidine kinase activity
GII85_01495	COG1131	(ABC) transporter
GII85_01515	COG3773	Cell wall hydrolase
GII85_01520	COG2304	oxidoreductase activity
GII85_01530	COG3540	Alkaline phosphatase
GII85_01535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII85_01540	COG0805	protein transport
GII85_01545	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII85_01550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII85_01555	COG0477	Major facilitator Superfamily
GII85_01560	COG1309	transcriptional regulator
GII85_01565	COG0252	asparaginase activity
GII85_01570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII85_01575	COG1714	RDD family
GII85_01580	COG3012	SEC-C Motif Domain Protein
GII85_01580	COG1405	negative regulation of cell septum assembly
GII85_01585	COG3290	protein histidine kinase activity
GII85_01590	COG3279	Response regulator of the LytR AlgR family
GII85_01595	COG4555	ABC transporter
GII85_01600	COG1668	transmembrane transport
GII85_01605	COG0667	Aldo Keto reductase
GII85_01620	COG1595	DNA-templated transcription, initiation
GII85_01625	COG1595	DNA-templated transcription, initiation
GII85_01630	COG1876	peptidase activity
GII85_01635	COG0457	Tetratricopeptide repeat
GII85_01640	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_01645	COG0366	Alpha amylase catalytic
GII85_01650	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII85_01655	COG1121	(ABC) transporter
GII85_01660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII85_01665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII85_01670	COG2310	stress, protein
GII85_01675	COG2310	stress, protein
GII85_01680	COG2310	stress, protein
GII85_01685	COG0861	Integral membrane protein TerC family
GII85_01695	COG3853	Toxic anion resistance protein (TelA)
GII85_01700	COG0477	Major facilitator Superfamily
GII85_01705	COG2814	Major facilitator Superfamily
GII85_01710	COG0640	Transcriptional regulator
GII85_01715	COG0517	IMP dehydrogenase activity
GII85_01715	COG4175	Glycine betaine
GII85_01720	COG4176	ABC-type proline glycine betaine transport system permease component
GII85_01725	COG2113	Glycine betaine
GII85_01730	COG1473	amidohydrolase
GII85_01735	COG1288	antiporter activity
GII85_01745	COG0366	Alpha amylase catalytic
GII85_01750	COG0039	L-malate dehydrogenase activity
GII85_01755	COG1620	l-lactate permease
GII85_01760	COG2814	Major facilitator Superfamily
GII85_01765	COG1846	Transcriptional regulator
GII85_01770	COG1280	lysine exporter protein (LysE YggA)
GII85_01775	COG3403	YqcI/YcgG family
GII85_01780	COG1113	amino acid transport
GII85_01785	COG3665	Urea carboxylase-associated protein
GII85_01790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII85_01795	COG1660	Displays ATPase and GTPase activities
GII85_01800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII85_01805	COG2226	methyltransferase
GII85_01810	COG0583	DNA-binding transcription factor activity
GII85_01815	COG3458	cephalosporin-C deacetylase activity
GII85_01820	COG3541	Predicted nucleotidyltransferase
GII85_01825	COG0506	proline dehydrogenase activity
GII85_01830	COG1012	belongs to the aldehyde dehydrogenase family
GII85_01835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII85_01840	COG2508	Transcriptional regulator
GII85_01845	COG3689	TIGRFAM TIGR03943 family protein
GII85_01850	COG0701	Predicted permease
GII85_01855	COG2267	carboxylic ester hydrolase activity
GII85_01860	COG0492	ferredoxin-NADP+ reductase activity
GII85_01865	COG1587	Uroporphyrinogen-III synthase
GII85_01865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII85_01870	COG2146	nitrite reductase [NAD(P)H] activity
GII85_01875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII85_01880	COG0243	molybdopterin cofactor binding
GII85_01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII85_01890	COG2223	nitrite transmembrane transporter activity
GII85_01895	COG1469	GTP cyclohydrolase I activity
GII85_01900	COG1376	ErfK ybiS ycfS ynhG family protein
GII85_01910	COG0523	cobalamin synthesis protein
GII85_01915	COG0765	amino acid transport
GII85_01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII85_01930	COG1714	RDD family
GII85_01940	COG2723	6-phospho-beta-galactosidase activity
GII85_01950	COG3209	COG3209 Rhs family protein
GII85_01955	COG0840	transmembrane signaling receptor activity
GII85_01955	COG3290	protein histidine kinase activity
GII85_01960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII85_01965	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII85_01970	COG1733	regulation of RNA biosynthetic process
GII85_01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_01990	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII85_01995	COG2814	Major facilitator Superfamily
GII85_02005	COG0697	spore germination
GII85_02010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII85_02020	COG2364	Membrane
GII85_02025	COG1126	abc transporter atp-binding protein
GII85_02030	COG0765	amino acid transport
GII85_02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII85_02040	COG0583	DNA-binding transcription factor activity
GII85_02045	COG0163	prenyltransferase activity
GII85_02050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII85_02065	COG0596	Alpha beta hydrolase
GII85_02070	COG3104	oligopeptide transport
GII85_02075	COG5434	Belongs to the glycosyl hydrolase 28 family
GII85_02085	COG0697	spore germination
GII85_02095	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII85_02100	COG1136	(ABC) transporter
GII85_02105	COG0577	efflux transmembrane transporter activity
GII85_02110	COG0745	RESPONSE REGULATOR receiver
GII85_02115	COG3850	Histidine kinase
GII85_02115	COG5002	protein histidine kinase activity
GII85_02120	COG0457	Tetratricopeptide repeat
GII85_02140	COG0527	aspartate kinase activity
GII85_02145	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII85_02150	COG4605	iron ion homeostasis
GII85_02155	COG4604	ABC transporter, ATP-binding protein
GII85_02160	COG4607	ABC-type enterochelin transport system periplasmic component
GII85_02165	COG2814	Major facilitator Superfamily
GII85_02170	COG1309	transcriptional regulator
GII85_02175	COG0778	Nitroreductase
GII85_02180	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII85_02185	COG0640	Transcriptional regulator
GII85_02190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII85_02195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII85_02200	COG1012	belongs to the aldehyde dehydrogenase family
GII85_02205	COG4975	Glucose uptake
GII85_02210	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_02215	COG4549	nuclear export factor GLE1
GII85_02220	COG1276	copper resistance
GII85_02220	COG2372	response to copper ion
GII85_02225	COG1349	DNA-binding transcription factor activity
GII85_02235	COG2213	PTS system mannitol-specific
GII85_02240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII85_02245	COG0246	Mannitol dehydrogenase
GII85_02250	COG0473	3-isopropylmalate dehydrogenase activity
GII85_02255	COG0681	Belongs to the peptidase S26 family
GII85_02260	COG0412	Dienelactone hydrolase
GII85_02265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII85_02275	COG0561	phosphatase activity
GII85_02280	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII85_02285	COG1914	H( )-stimulated, divalent metal cation uptake system
GII85_02290	COG4336	lyase activity
GII85_02295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII85_02300	COG1984	allophanate hydrolase subunit 2
GII85_02305	COG1414	Transcriptional regulator
GII85_02310	COG2755	lipolytic protein G-D-S-L family
GII85_02320	COG2329	Antibiotic biosynthesis monooxygenase
GII85_02325	COG0768	penicillin binding
GII85_02330	COG4989	oxidoreductase activity
GII85_02335	COG3711	transcriptional antiterminator
GII85_02340	COG0318	PFAM AMP-dependent synthetase and ligase
GII85_02345	COG2226	methyltransferase
GII85_02350	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_02355	COG1917	Cupin 2, conserved barrel domain protein
GII85_02360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII85_02365	COG3871	stress protein (general stress protein 26)
GII85_02375	COG2814	Major facilitator Superfamily
GII85_02380	COG1522	sequence-specific DNA binding
GII85_02385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII85_02385	COG0551	DNA topoisomerase type I activity
GII85_02390	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII85_02395	COG3706	GGDEF domain
GII85_02400	COG5298	Protein conserved in bacteria
GII85_02405	COG1215	transferase activity, transferring glycosyl groups
GII85_02415	COG0531	amino acid
GII85_02420	COG0494	nUDIX hydrolase
GII85_02425	COG0028	Belongs to the TPP enzyme family
GII85_02440	COG1914	H( )-stimulated, divalent metal cation uptake system
GII85_02445	COG2261	transglycosylase associated protein
GII85_02450	COG4876	unkown
GII85_02455	COG2217	Heavy metal translocating P-type atpase
GII85_02460	COG3729	General stress protein
GII85_02465	COG0662	Cupin 2, conserved barrel domain protein
GII85_02470	COG2329	Antibiotic biosynthesis monooxygenase
GII85_02475	COG3546	catalase activity
GII85_02480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII85_02485	COG3290	protein histidine kinase activity
GII85_02490	COG4565	transcriptional regulatory protein
GII85_02495	COG1301	dicarboxylic acid transport
GII85_02500	COG0628	permease
GII85_02505	COG1131	(ABC) transporter
GII85_02510	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII85_02520	COG1960	acyl-CoA dehydrogenase activity
GII85_02535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII85_02540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII85_02545	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII85_02550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII85_02555	COG0513	Belongs to the DEAD box helicase family
GII85_02560	COG3402	PFAM membrane-flanked domain
GII85_02565	COG3428	Bacterial PH domain
GII85_02570	COG0705	Rhomboid family
GII85_02575	COG0736	holo-[acyl-carrier-protein] synthase activity
GII85_02580	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII85_02585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII85_02590	COG0864	Transcriptional regulator
GII85_02595	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII85_02600	COG1366	Belongs to the anti-sigma-factor antagonist family
GII85_02605	COG1366	Belongs to the anti-sigma-factor antagonist family
GII85_02610	COG2172	sigma factor antagonist activity
GII85_02615	COG2208	phosphoserine phosphatase activity
GII85_02620	COG1366	Belongs to the anti-sigma-factor antagonist family
GII85_02625	COG2172	sigma factor antagonist activity
GII85_02630	COG1191	sigma factor activity
GII85_02635	COG2208	phosphoserine phosphatase activity
GII85_02640	COG2183	response to ionizing radiation
GII85_02650	COG3091	SprT-like family
GII85_02730	COG5444	nuclease activity
GII85_02740	COG1476	TRANSCRIPTIONal
GII85_02750	COG3239	Fatty acid desaturase
GII85_02755	COG1278	Cold shock
GII85_02760	COG1329	Transcriptional regulator
GII85_02765	COG0697	spore germination
GII85_02770	COG2207	Transcriptional regulator
GII85_02770	COG1917	Cupin 2, conserved barrel domain protein
GII85_02775	COG0697	spore germination
GII85_02780	COG3708	Transcriptional regulator
GII85_02780	COG2207	Transcriptional regulator
GII85_02785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII85_02790	COG0477	Major facilitator Superfamily
GII85_02800	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII85_02815	COG1309	transcriptional regulator
GII85_02820	COG0697	spore germination
GII85_02825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII85_02830	COG2030	dehydratase
GII85_02835	COG3545	Serine hydrolase
GII85_02840	COG1733	regulation of RNA biosynthetic process
GII85_02845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII85_02850	COG1733	regulation of RNA biosynthetic process
GII85_02855	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII85_02860	COG2814	Major facilitator Superfamily
GII85_02865	COG1309	transcriptional regulator
GII85_02870	COG0640	Transcriptional regulator
GII85_02875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII85_02885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII85_02890	COG0697	spore germination
GII85_02895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII85_02900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII85_02905	COG0640	Transcriptional regulator
GII85_02910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII85_02925	COG4585	Histidine kinase
GII85_02930	COG2197	response regulator
GII85_02935	COG2409	Drug exporters of the RND superfamily
GII85_02940	COG0596	Alpha beta hydrolase
GII85_02945	COG1811	Na channel or pump
GII85_02950	COG4978	Transcriptional regulator
GII85_02950	COG0789	Transcriptional regulator
GII85_02955	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII85_02960	COG0778	Nitroreductase
GII85_02965	COG0346	lactoylglutathione lyase activity
GII85_02970	COG2259	Doxx family
GII85_02975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII85_02990	COG2323	membrane
GII85_02995	COG2323	membrane
GII85_03000	COG0071	Belongs to the small heat shock protein (HSP20) family
GII85_03015	COG1309	transcriptional regulator
GII85_03025	COG0456	acetyltransferase
GII85_03035	COG1113	amino acid transport
GII85_03040	COG2318	DinB family
GII85_03045	COG1846	Transcriptional regulator
GII85_03050	COG2409	Drug exporters of the RND superfamily
GII85_03050	COG1033	growth of symbiont in host cell
GII85_03055	COG0778	Nitroreductase
GII85_03060	COG1846	Transcriptional regulator
GII85_03065	COG2814	Major facilitator Superfamily
GII85_03070	COG0730	response to heat
GII85_03075	COG1802	Transcriptional regulator
GII85_03080	COG1388	LysM domain
GII85_03080	COG3858	chitin binding
GII85_03085	COG1819	glycosyl
GII85_03095	COG1785	Belongs to the alkaline phosphatase family
GII85_03100	COG5646	InterPro IPR014922
GII85_03110	COG0454	-acetyltransferase
GII85_03115	COG1078	dGTPase activity
GII85_03120	COG1388	LysM domain
GII85_03125	COG2814	Major facilitator Superfamily
GII85_03130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII85_03135	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII85_03140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII85_03145	COG2723	6-phospho-beta-galactosidase activity
GII85_03150	COG2188	Transcriptional regulator
GII85_03155	COG1940	carbohydrate kinase activity
GII85_03160	COG1482	cell wall glycoprotein biosynthetic process
GII85_03165	COG4124	Belongs to the glycosyl hydrolase 26 family
GII85_03210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII85_03215	COG0802	atpase or kinase
GII85_03220	COG1214	PFAM Peptidase M22, glycoprotease
GII85_03225	COG0456	acetyltransferase
GII85_03230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII85_03235	COG0488	(ABC) transporter
GII85_03240	COG0315	cyclic pyranopterin monophosphate synthase activity
GII85_03245	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII85_03250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII85_03255	COG0805	protein transport
GII85_03265	COG1266	CAAX protease self-immunity
GII85_03270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GII85_03275	COG0459	protein refolding
GII85_03285	COG1073	alpha beta
GII85_03290	COG0457	Tetratricopeptide repeat
GII85_03295	COG1063	alcohol dehydrogenase
GII85_03300	COG2211	Major facilitator Superfamily
GII85_03305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII85_03310	COG1842	Phage shock protein A
GII85_03315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII85_03320	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII85_03325	COG4260	virion core protein, lumpy skin disease virus
GII85_03335	COG2814	Major facilitator Superfamily
GII85_03340	COG1063	alcohol dehydrogenase
GII85_03345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII85_03350	COG0823	Involved in the tonB-independent uptake of proteins
GII85_03365	COG2267	carboxylic ester hydrolase activity
GII85_03375	COG2132	Multicopper oxidase
GII85_03380	COG1113	amino acid transport
GII85_03390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII85_03395	COG0714	Associated with various cellular activities
GII85_03400	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII85_03405	COG1305	Transglutaminase-like
GII85_03410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII85_03410	COG0519	Catalyzes the synthesis of GMP from XMP
GII85_03425	COG2252	PERMEase
GII85_03430	COG3064	Membrane
GII85_03440	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII85_03450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII85_03455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII85_03460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII85_03465	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII85_03470	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII85_03475	COG0047	phosphoribosylformylglycinamidine synthase activity
GII85_03480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII85_03485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII85_03490	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII85_03495	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII85_03500	COG0138	bifunctional purine biosynthesis protein purh
GII85_03505	COG0151	Belongs to the GarS family
GII85_03510	COG1522	sequence-specific DNA binding
GII85_03515	COG0531	amino acid
GII85_03525	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII85_03530	COG1470	cell adhesion involved in biofilm formation
GII85_03535	COG4496	protein, YerC YecD
GII85_03540	COG0069	glutamate synthase activity
GII85_03545	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII85_03550	COG0210	DNA helicase
GII85_03555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII85_03560	COG4851	CamS sex pheromone cAM373 precursor
GII85_03565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII85_03570	COG1285	pathogenesis
GII85_03575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII85_03580	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII85_03585	COG0154	amidase activity
GII85_03590	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII85_03595	COG1309	transcriptional regulator
GII85_03600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII85_03605	COG1597	lipid kinase activity
GII85_03610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII85_03625	COG5444	nuclease activity
GII85_03630	COG3391	amine dehydrogenase activity
GII85_03635	COG0457	Tetratricopeptide repeat
GII85_03645	COG0217	transcriptional regulatory protein
GII85_03655	COG1309	transcriptional regulator
GII85_03660	COG3631	Ketosteroid isomerase-related protein
GII85_03665	COG0702	epimerase
GII85_03680	COG3546	catalase activity
GII85_03685	COG0454	-acetyltransferase
GII85_03695	COG5578	integral membrane protein
GII85_03700	COG2972	Histidine kinase
GII85_03705	COG4753	response regulator
GII85_03705	COG2207	Transcriptional regulator
GII85_03710	COG1653	transport
GII85_03715	COG1175	transmembrane transport
GII85_03720	COG0395	ABC-type sugar transport system, permease component
GII85_03725	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII85_03730	COG2207	Transcriptional regulator
GII85_03735	COG2755	lipolytic protein G-D-S-L family
GII85_03745	COG5578	integral membrane protein
GII85_03750	COG3401	FG-GAP repeat protein
GII85_03755	COG3401	FG-GAP repeat protein
GII85_03760	COG2755	lipolytic protein G-D-S-L family
GII85_03765	COG1874	Beta-galactosidase
GII85_03775	COG1653	transport
GII85_03780	COG4209	transmembrane transport
GII85_03785	COG0395	ABC-type sugar transport system, permease component
GII85_03790	COG1486	melibiose metabolic process
GII85_03795	COG2323	membrane
GII85_03800	COG2329	Antibiotic biosynthesis monooxygenase
GII85_03805	COG0346	lactoylglutathione lyase activity
GII85_03820	COG5583	Uncharacterized small protein (DUF2292)
GII85_03825	COG0670	Belongs to the BI1 family
GII85_03830	COG0697	spore germination
GII85_03835	COG1846	Transcriptional regulator
GII85_03840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII85_03855	COG2124	cytochrome p450
GII85_03855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII85_03860	COG1368	sulfuric ester hydrolase activity
GII85_03865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII85_03870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII85_03875	COG1442	glycosyl transferase family 8
GII85_03880	COG1216	Glycosyl transferase, family 2
GII85_03885	COG1442	glycosyl transferase family 8
GII85_03890	COG2223	nitrite transmembrane transporter activity
GII85_03895	COG1011	Hydrolase
GII85_03900	COG0531	amino acid
GII85_03905	COG1012	belongs to the aldehyde dehydrogenase family
GII85_03910	COG0840	transmembrane signaling receptor activity
GII85_03915	COG0488	(ABC) transporter
GII85_03925	COG0789	Transcriptional regulator
GII85_03930	COG2814	Major facilitator Superfamily
GII85_03935	COG1404	Belongs to the peptidase S8 family
GII85_03955	COG0488	(ABC) transporter
GII85_03960	COG0513	Belongs to the DEAD box helicase family
GII85_03965	COG0456	acetyltransferase
GII85_03970	COG2130	NADP-dependent
GII85_03975	COG1120	ATPase activity
GII85_03980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII85_03985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII85_03990	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII85_04005	COG3866	Pectate lyase
GII85_04010	COG0471	metal ion transport
GII85_04015	COG3290	protein histidine kinase activity
GII85_04020	COG4565	transcriptional regulatory protein
GII85_04025	COG3181	Tripartite tricarboxylate transporter family receptor
GII85_04030	COG2851	Citrate transporter
GII85_04035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII85_04040	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII85_04045	COG1254	Belongs to the acylphosphatase family
GII85_04050	COG2258	MOSC domain
GII85_04070	COG0024	Methionine aminopeptidase
GII85_04075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII85_04075	COG1263	PTS System
GII85_04080	COG1368	sulfuric ester hydrolase activity
GII85_04100	COG0531	amino acid
GII85_04115	COG0697	spore germination
GII85_04120	COG1263	PTS System
GII85_04120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII85_04125	COG0366	Alpha amylase catalytic
GII85_04130	COG2188	Transcriptional regulator
GII85_04135	COG0778	Nitroreductase
GII85_04140	COG0737	Belongs to the 5'-nucleotidase family
GII85_04145	COG0693	protein deglycase activity
GII85_04150	COG2814	Major facilitator Superfamily
GII85_04155	COG4840	Belongs to the UPF0435 family
GII85_04160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII85_04165	COG4980	gas vesicle protein
GII85_04170	COG1295	ribonuclease BN
GII85_04175	COG0477	Major facilitator Superfamily
GII85_04180	COG0387	Pfam Sodium calcium exchanger
GII85_04190	COG0668	transmembrane transport
GII85_04195	COG0535	radical SAM domain protein
GII85_04205	COG0726	polysaccharide deacetylase
GII85_04210	COG2084	Dehydrogenase
GII85_04215	COG0598	Magnesium transport protein CorA
GII85_04220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII85_04225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII85_04235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII85_04240	COG4637	Psort location Cytoplasmic, score
GII85_04250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII85_04255	COG0022	dehydrogenase e1 component
GII85_04260	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII85_04265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII85_04270	COG3284	Transcriptional regulator
GII85_04280	COG1742	UPF0060 membrane protein
GII85_04305	COG4842	Belongs to the WXG100 family
GII85_04310	COG1486	melibiose metabolic process
GII85_04315	COG1737	Transcriptional regulator
GII85_04320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII85_04320	COG1263	PTS System
GII85_04325	COG5434	Belongs to the glycosyl hydrolase 28 family
GII85_04330	COG1132	(ABC) transporter
GII85_04335	COG1132	(ABC) transporter
GII85_04340	COG2259	Doxx family
GII85_04345	COG2514	catechol 2,3-dioxygenase activity
GII85_04350	COG4977	sequence-specific DNA binding
GII85_04350	COG1917	Cupin 2, conserved barrel domain protein
GII85_04355	COG2814	Major facilitator Superfamily
GII85_04360	COG1082	Xylose isomerase domain protein TIM barrel
GII85_04365	COG0673	inositol 2-dehydrogenase activity
GII85_04370	COG4585	Histidine kinase
GII85_04375	COG2197	response regulator
GII85_04380	COG1131	(ABC) transporter
GII85_04385	COG0842	Transport permease protein
GII85_04385	COG1511	domain protein
GII85_04390	COG0842	Transport permease protein
GII85_04395	COG1695	Transcriptional regulator
GII85_04400	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII85_04405	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII85_04410	COG1309	transcriptional regulator
GII85_04415	COG2814	Major facilitator Superfamily
GII85_04420	COG2318	DinB family
GII85_04425	COG2814	Major facilitator Superfamily
GII85_04430	COG1846	Transcriptional regulator
GII85_04435	COG0392	lysyltransferase activity
GII85_04435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII85_04440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII85_04445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII85_04450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII85_04455	COG0384	phenazine biosynthesis protein PhzF
GII85_04460	COG0778	Nitroreductase
GII85_04475	COG1090	epimerase
GII85_04480	COG2137	regulation of response to DNA damage stimulus
GII85_04490	COG2814	Major facilitator Superfamily
GII85_04505	COG3103	Sh3 type 3 domain protein
GII85_04510	COG5658	integral membrane protein
GII85_04515	COG0596	Alpha beta hydrolase
GII85_04520	COG0463	Glycosyl transferase, family 2
GII85_04525	COG4485	Bacterial membrane protein, YfhO
GII85_04530	COG1988	membrane-bound metal-dependent
GII85_04535	COG1194	a g-specific adenine glycosylase
GII85_04545	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_04560	COG3557	Belongs to the UPF0374 family
GII85_04565	COG1132	(ABC) transporter
GII85_04570	COG4129	membrane
GII85_04575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII85_04580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII85_04585	COG0735	belongs to the Fur family
GII85_04695	COG4326	sporulation control protein
GII85_04705	COG5577	PFAM Coat F domain
GII85_04715	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII85_04730	COG0753	catalase activity
GII85_04735	COG1116	anion transmembrane transporter activity
GII85_04740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII85_04745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII85_04750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII85_04760	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII85_04770	COG1476	TRANSCRIPTIONal
GII85_04780	COG3382	B3 4 domain protein
GII85_04785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII85_04795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII85_04800	COG0789	Transcriptional regulator
GII85_04805	COG1664	Polymer-forming cytoskeletal
GII85_04810	COG1664	Polymer-forming cytoskeletal
GII85_04815	COG2766	serine protein kinase
GII85_04820	COG2718	Belongs to the UPF0229 family
GII85_04825	COG1846	Transcriptional regulator
GII85_04830	COG1566	PFAM secretion protein HlyD family protein
GII85_04835	COG2814	Major facilitator Superfamily
GII85_04840	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII85_04860	COG1725	Transcriptional regulator
GII85_04865	COG1131	(ABC) transporter
GII85_04870	COG1131	(ABC) transporter
GII85_04875	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII85_04880	COG1278	Cold shock
GII85_04885	COG1464	Belongs to the NlpA lipoprotein family
GII85_04890	COG3706	GGDEF domain
GII85_04895	COG1823	symporter activity
GII85_04925	COG5577	PFAM Coat F domain
GII85_04930	COG1525	nuclease
GII85_04930	COG4085	toxin activity
GII85_04930	COG0737	Belongs to the 5'-nucleotidase family
GII85_04935	COG3764	Sortase (surface protein transpeptidase)
GII85_04940	COG0564	pseudouridine synthase activity
GII85_04950	COG0517	IMP dehydrogenase activity
GII85_04955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII85_04960	COG3153	acetyltransferase
GII85_04960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII85_04965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII85_04970	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII85_04975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII85_04980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII85_04985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII85_04990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII85_04995	COG4585	Histidine kinase
GII85_04995	COG2203	Gaf domain
GII85_05000	COG2197	response regulator
GII85_05005	COG0431	NADPH-dependent FMN reductase
GII85_05020	COG0791	NLP P60 protein
GII85_05020	COG1388	LysM domain
GII85_05025	COG1959	2 iron, 2 sulfur cluster binding
GII85_05030	COG0668	transmembrane transport
GII85_05035	COG2719	SpoVR family
GII85_05040	COG1785	Belongs to the alkaline phosphatase family
GII85_05045	COG0791	NLP P60 protein
GII85_05045	COG1388	LysM domain
GII85_05050	COG0583	DNA-binding transcription factor activity
GII85_05055	COG0372	Belongs to the citrate synthase family
GII85_05060	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_05065	COG0531	amino acid
GII85_05070	COG0733	neurotransmitter:sodium symporter activity
GII85_05075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII85_05080	COG0456	acetyltransferase
GII85_05095	COG1595	DNA-templated transcription, initiation
GII85_05100	COG0667	Aldo Keto reductase
GII85_05105	COG0204	Acyl-transferase
GII85_05110	COG1253	flavin adenine dinucleotide binding
GII85_05115	COG0789	Transcriptional regulator
GII85_05120	COG0436	Aminotransferase
GII85_05125	COG1253	flavin adenine dinucleotide binding
GII85_05130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII85_05135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII85_05140	COG0584	glycerophosphoryl diester phosphodiesterase
GII85_05150	COG0668	transmembrane transport
GII85_05155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII85_05160	COG0726	polysaccharide deacetylase
GII85_05165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII85_05170	COG1757	Na H antiporter
GII85_05175	COG0589	response to stress
GII85_05185	COG1132	(ABC) transporter
GII85_05190	COG1132	(ABC) transporter
GII85_05195	COG0702	epimerase
GII85_05215	COG0189	ligase activity
GII85_05220	COG0189	ligase activity
GII85_05225	COG4399	Belongs to the UPF0754 family
GII85_05230	COG3679	Belongs to the UPF0342 family
GII85_05235	COG4335	DNA alkylation repair
GII85_05240	COG0561	phosphatase activity
GII85_05245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII85_05250	COG0475	glutathione-regulated potassium exporter activity
GII85_05255	COG0490	domain, Protein
GII85_05265	COG1024	Enoyl-CoA hydratase
GII85_05275	COG4152	abc transporter atp-binding protein
GII85_05280	COG1668	transmembrane transport
GII85_05285	COG0420	3'-5' exonuclease activity
GII85_05290	COG4717	serine-type aminopeptidase activity
GII85_05295	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII85_05305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII85_05335	COG1846	Transcriptional regulator
GII85_05340	COG4980	gas vesicle protein
GII85_05355	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII85_05360	COG0537	adenosine 5'-monophosphoramidase activity
GII85_05365	COG1131	(ABC) transporter
GII85_05370	COG4473	ABC transporter
GII85_05380	COG1473	amidohydrolase
GII85_05385	COG3069	C4-dicarboxylate transmembrane transporter activity
GII85_05395	COG2329	Antibiotic biosynthesis monooxygenase
GII85_05400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII85_05405	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII85_05420	COG1309	transcriptional regulator
GII85_05425	COG1511	domain protein
GII85_05430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII85_05435	COG4377	Putative membrane peptidase family (DUF2324)
GII85_05445	COG1363	Peptidase, m42
GII85_05450	COG4405	Protein conserved in bacteria
GII85_05455	COG1301	dicarboxylic acid transport
GII85_05465	COG1234	tRNA 3'-trailer cleavage
GII85_05470	COG0095	Lipoate-protein ligase
GII85_05475	COG0702	epimerase
GII85_05480	COG0318	PFAM AMP-dependent synthetase and ligase
GII85_05490	COG0501	Belongs to the peptidase M48B family
GII85_05500	COG0456	acetyltransferase
GII85_05505	COG0604	alcohol dehydrogenase
GII85_05510	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII85_05515	COG0406	alpha-ribazole phosphatase activity
GII85_05520	COG0183	Belongs to the thiolase family
GII85_05525	COG0318	PFAM AMP-dependent synthetase and ligase
GII85_05530	COG1268	BioY protein
GII85_05535	COG0840	transmembrane signaling receptor activity
GII85_05540	COG0723	plastoquinol--plastocyanin reductase activity
GII85_05540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII85_05545	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_05555	COG4903	ComK protein
GII85_05560	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_05570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII85_05585	COG0398	Pfam SNARE associated Golgi protein
GII85_05590	COG0681	Belongs to the peptidase S26 family
GII85_05595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII85_05600	COG1846	Transcriptional regulator
GII85_05610	COG0738	Major facilitator superfamily
GII85_05615	COG0673	inositol 2-dehydrogenase activity
GII85_05620	COG0561	phosphatase activity
GII85_05625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII85_05630	COG1609	Transcriptional regulator
GII85_05635	COG3180	Ammonia monooxygenase
GII85_05640	COG0477	Major facilitator Superfamily
GII85_05640	COG2814	Major facilitator Superfamily
GII85_05645	COG4533	DNA binding
GII85_05655	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII85_05660	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII85_05665	COG1074	ATP-dependent DNA helicase activity
GII85_05670	COG0420	3'-5' exonuclease activity
GII85_05675	COG0419	ATPase involved in DNA repair
GII85_05680	COG1403	HNH endonuclease
GII85_05720	COG5337	Spore coat protein CotH
GII85_05725	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII85_05735	COG1404	Belongs to the peptidase S8 family
GII85_05745	COG0367	asparagine synthase
GII85_05750	COG2318	DinB family
GII85_05755	COG1562	ergosterol biosynthetic process
GII85_05760	COG0534	Mate efflux family protein
GII85_05765	COG1917	Cupin 2, conserved barrel domain protein
GII85_05765	COG2207	Transcriptional regulator
GII85_05770	COG1609	Transcriptional regulator
GII85_05775	COG0673	inositol 2-dehydrogenase activity
GII85_05780	COG2318	DinB family
GII85_05785	COG1279	arginine transmembrane transporter activity
GII85_05790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII85_05795	COG1357	PFAM Pentapeptide repeats (8 copies)
GII85_05800	COG2267	carboxylic ester hydrolase activity
GII85_05805	COG0529	Catalyzes the synthesis of activated sulfate
GII85_05810	COG2046	Belongs to the sulfate adenylyltransferase family
GII85_05815	COG0175	sulfate reduction
GII85_05820	COG2045	Belongs to the ComB family
GII85_05825	COG1809	phosphosulfolactate synthase activity
GII85_05830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII85_05835	COG4948	Mandelate Racemase Muconate Lactonizing
GII85_05840	COG2814	Major facilitator Superfamily
GII85_05845	COG0454	-acetyltransferase
GII85_05850	COG2153	protein acetylation
GII85_05855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII85_05855	COG0646	methionine synthase
GII85_05860	COG1666	GTP binding
GII85_05865	COG2996	Protein conserved in bacteria
GII85_05885	COG1695	Transcriptional regulator
GII85_05900	COG3227	Zinc metalloprotease (Elastase)
GII85_05905	COG1307	EDD domain protein, DegV family
GII85_05910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII85_05925	COG0561	phosphatase activity
GII85_05930	COG1073	alpha beta
GII85_05935	COG2151	metal-sulfur cluster biosynthetic enzyme
GII85_05945	COG0277	FAD linked oxidase domain protein
GII85_05950	COG2271	Major facilitator Superfamily
GII85_05955	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII85_05970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII85_05975	COG0505	Belongs to the CarA family
GII85_05980	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII85_05985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII85_06000	COG2267	carboxylic ester hydrolase activity
GII85_06010	COG1744	ABC transporter substrate-binding protein PnrA-like
GII85_06025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII85_06030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII85_06035	COG5504	Zn-dependent protease
GII85_06040	COG0444	Belongs to the ABC transporter superfamily
GII85_06045	COG4608	Belongs to the ABC transporter superfamily
GII85_06055	COG0601	transmembrane transport
GII85_06060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII85_06070	COG0180	Tryptophanyl-tRNA synthetase
GII85_06075	COG4166	transmembrane transport
GII85_06080	COG0601	transmembrane transport
GII85_06085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII85_06090	COG0444	Belongs to the ABC transporter superfamily
GII85_06095	COG4608	Belongs to the ABC transporter superfamily
GII85_06100	COG2814	Major facilitator Superfamily
GII85_06105	COG0456	acetyltransferase
GII85_06110	COG1393	Belongs to the ArsC family
GII85_06115	COG0861	Integral membrane protein TerC family
GII85_06125	COG4862	establishment of competence for transformation
GII85_06135	COG4469	Competence protein
GII85_06140	COG1164	Oligoendopeptidase f
GII85_06155	COG2346	COG2346, Truncated hemoglobins
GII85_06160	COG0741	lytic transglycosylase activity
GII85_06165	COG4116	CYTH
GII85_06175	COG2357	RelA SpoT domain protein
GII85_06180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII85_06185	COG0564	pseudouridine synthase activity
GII85_06190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII85_06195	COG0569	domain protein
GII85_06195	COG0475	glutathione-regulated potassium exporter activity
GII85_06200	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII85_06205	COG0352	thiamine-phosphate diphosphorylase activity
GII85_06210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII85_06215	COG2104	thiamine diphosphate biosynthetic process
GII85_06220	COG2022	thiamine diphosphate biosynthetic process
GII85_06225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII85_06230	COG0351	phosphomethylpyrimidine kinase
GII85_06235	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII85_06290	COG0210	DNA helicase
GII85_06300	COG2153	protein acetylation
GII85_06305	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII85_06310	COG2382	esterase
GII85_06315	COG0626	cystathionine gamma-synthase activity
GII85_06320	COG0626	cystathionine gamma-synthase activity
GII85_06325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII85_06330	COG5505	Protein of unknown function (DUF819)
GII85_06385	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII85_06390	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_06400	COG3711	transcriptional antiterminator
GII85_06400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII85_06405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII85_06405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII85_06405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII85_06410	COG1482	cell wall glycoprotein biosynthetic process
GII85_06420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII85_06430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII85_06445	COG0109	protoheme IX farnesyltransferase activity
GII85_06455	COG0726	polysaccharide deacetylase
GII85_06475	COG2205	protein histidine kinase activity
GII85_06485	COG3383	formate dehydrogenase (NAD+) activity
GII85_06490	COG2427	Protein of unknown function (DUF1641)
GII85_06500	COG1051	belongs to the nudix hydrolase family
GII85_06510	COG2124	cytochrome p450
GII85_06515	COG1819	glycosyl
GII85_06525	COG1587	Uroporphyrinogen-III synthase
GII85_06530	COG0390	transport system, permease component
GII85_06535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII85_06540	COG0697	spore germination
GII85_06545	COG4297	protein containing double-stranded beta helix domain
GII85_06555	COG1252	NADH dehydrogenase
GII85_06560	COG1904	glucuronate isomerase
GII85_06565	COG2211	Major facilitator Superfamily
GII85_06570	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII85_06575	COG1063	alcohol dehydrogenase
GII85_06580	COG1312	Catalyzes the dehydration of D-mannonate
GII85_06585	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_06590	COG2271	Major facilitator Superfamily
GII85_06595	COG1609	Transcriptional regulator
GII85_06600	COG0246	Mannitol dehydrogenase
GII85_06605	COG2721	sulfolactate sulfo-lyase activity
GII85_06610	COG0730	response to heat
GII85_06615	COG2318	DinB family
GII85_06620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII85_06625	COG0457	Tetratricopeptide repeat
GII85_06635	COG2350	Protein conserved in bacteria
GII85_06640	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII85_06640	COG1388	LysM domain
GII85_06640	COG3409	Peptidoglycan-binding domain 1 protein
GII85_06650	COG4195	phage-related replication protein
GII85_06655	COG3546	catalase activity
GII85_06660	COG2856	Zn peptidase
GII85_06665	COG1396	sequence-specific DNA binding
GII85_06675	COG1522	sequence-specific DNA binding
GII85_06680	COG1484	DNA-dependent DNA replication
GII85_06700	COG1595	DNA-templated transcription, initiation
GII85_06705	COG3728	DNA packaging
GII85_06705	COG5484	DNA packaging
GII85_06710	COG1783	phage Terminase large subunit
GII85_06715	COG5518	Phage portal protein
GII85_06720	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII85_06725	COG4653	Phage capsid family
GII85_06775	COG3953	SLT domain
GII85_06775	COG5412	phage tail tape measure protein
GII85_06780	COG1652	LysM domain
GII85_06785	COG4193	domain, Protein
GII85_06795	COG3628	GPW Gp25 family protein
GII85_06800	COG3299	homolog of phage Mu protein gp47
GII85_06805	COG3778	Protein conserved in bacteria
GII85_06845	COG3409	Peptidoglycan-binding domain 1 protein
GII85_06845	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII85_06865	COG0306	phosphate transporter
GII85_06870	COG1392	Phosphate transport regulator
GII85_06875	COG0531	amino acid
GII85_06880	COG0346	lactoylglutathione lyase activity
GII85_06890	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII85_06895	COG0463	Glycosyl transferase, family 2
GII85_06900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII85_06905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII85_06910	COG2362	D-Aminopeptidase
GII85_06915	COG0601	transmembrane transport
GII85_06920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII85_06925	COG0444	Belongs to the ABC transporter superfamily
GII85_06930	COG4166	transmembrane transport
GII85_06935	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII85_06940	COG4948	Mandelate Racemase Muconate Lactonizing
GII85_06945	COG0791	NLP P60 protein
GII85_06950	COG4608	Belongs to the ABC transporter superfamily
GII85_06955	COG2706	6-phosphogluconolactonase activity
GII85_06960	COG1834	amidinotransferase
GII85_06965	COG1607	acyl-coa hydrolase
GII85_06970	COG1017	nitric oxide dioxygenase activity
GII85_06970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII85_06980	COG2323	membrane
GII85_06985	COG2318	DinB family
GII85_06990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII85_06995	COG2076	Multidrug Resistance protein
GII85_07000	COG2076	Multidrug Resistance protein
GII85_07005	COG0788	formyltetrahydrofolate deformylase activity
GII85_07010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII85_07015	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII85_07020	COG1764	response to oxidative stress
GII85_07025	COG1846	Transcriptional regulator
GII85_07030	COG1764	response to oxidative stress
GII85_07040	COG0590	tRNA wobble adenosine to inosine editing
GII85_07045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII85_07050	COG1404	Belongs to the peptidase S8 family
GII85_07055	COG1366	Belongs to the anti-sigma-factor antagonist family
GII85_07060	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII85_07065	COG1122	ATPase activity
GII85_07070	COG4721	ABC-type cobalt transport system, permease component
GII85_07080	COG0745	RESPONSE REGULATOR receiver
GII85_07085	COG3850	Histidine kinase
GII85_07085	COG5002	protein histidine kinase activity
GII85_07090	COG3212	peptidase
GII85_07095	COG3212	peptidase
GII85_07110	COG2239	Acts as a magnesium transporter
GII85_07115	COG0789	Transcriptional regulator
GII85_07130	COG1846	Transcriptional regulator
GII85_07135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII85_07140	COG0726	polysaccharide deacetylase
GII85_07145	COG1408	metallophosphoesterase
GII85_07155	COG0463	Glycosyl transferase, family 2
GII85_07160	COG1793	dna ligase
GII85_07160	COG3285	dna ligase
GII85_07165	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII85_07170	COG5001	Diguanylate cyclase
GII85_07170	COG3300	MHYT domain
GII85_07175	COG0586	Pfam SNARE associated Golgi protein
GII85_07180	COG0861	Integral membrane protein TerC family
GII85_07185	COG1191	sigma factor activity
GII85_07205	COG0501	Belongs to the peptidase M48B family
GII85_07210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII85_07225	COG3594	Acyltransferase
GII85_07230	COG5002	protein histidine kinase activity
GII85_07235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII85_07245	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII85_07250	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII85_07255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII85_07260	COG0436	Aminotransferase
GII85_07265	COG1850	ribulose-bisphosphate carboxylase activity
GII85_07270	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII85_07275	COG0235	Class ii aldolase
GII85_07280	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII85_07285	COG3339	Conserved Protein
GII85_07300	COG3852	Histidine kinase
GII85_07305	COG1846	Transcriptional regulator
GII85_07310	COG1360	Flagellar Motor Protein
GII85_07315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII85_07320	COG0542	response to heat
GII85_07325	COG3949	Membrane
GII85_07330	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII85_07335	COG0720	synthase
GII85_07340	COG0602	queuosine metabolic process
GII85_07345	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII85_07350	COG1733	regulation of RNA biosynthetic process
GII85_07355	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_07360	COG1388	LysM domain
GII85_07360	COG4641	Protein conserved in bacteria
GII85_07365	COG1388	LysM domain
GII85_07370	COG3858	chitin binding
GII85_07380	COG4873	Protein conserved in bacteria
GII85_07390	COG3773	Cell wall hydrolase
GII85_07395	COG2244	polysaccharide biosynthetic process
GII85_07400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII85_07405	COG2217	Heavy metal translocating P-type atpase
GII85_07415	COG0006	proline dipeptidase activity
GII85_07420	COG1609	Transcriptional regulator
GII85_07425	COG3711	transcriptional antiterminator
GII85_07430	COG1263	PTS System
GII85_07430	COG2190	(PTS) system
GII85_07430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII85_07435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII85_07440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII85_07450	COG1533	DNA photolyase activity
GII85_07455	COG0456	acetyltransferase
GII85_07460	COG0840	transmembrane signaling receptor activity
GII85_07465	COG2084	Dehydrogenase
GII85_07470	COG4257	antibiotic catabolic process
GII85_07475	COG2340	Cysteine-rich secretory protein family
GII85_07480	COG0768	penicillin binding
GII85_07485	COG4191	Histidine kinase
GII85_07490	COG0436	Aminotransferase
GII85_07500	COG0835	chemotaxis
GII85_07500	COG0784	Response regulator, receiver
GII85_07510	COG2814	Major facilitator Superfamily
GII85_07515	COG1376	ErfK ybiS ycfS ynhG family protein
GII85_07520	COG1408	metallophosphoesterase
GII85_07525	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_07530	COG2200	EAL domain
GII85_07535	COG4703	Protein of unknown function (DUF1797)
GII85_07540	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII85_07550	COG0517	IMP dehydrogenase activity
GII85_07555	COG0583	DNA-binding transcription factor activity
GII85_07560	COG0716	FMN binding
GII85_07570	COG0716	FMN binding
GII85_07575	COG2171	N-acyltransferase activity
GII85_07580	COG1473	amidohydrolase
GII85_07590	COG0668	transmembrane transport
GII85_07595	COG0450	alkyl hydroperoxide reductase
GII85_07600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII85_07615	COG0746	molybdenum cofactor guanylyltransferase activity
GII85_07620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII85_07625	COG0303	'Molybdopterin
GII85_07630	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII85_07635	COG0314	molybdopterin synthase activity
GII85_07640	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII85_07645	COG1132	(ABC) transporter
GII85_07650	COG1132	(ABC) transporter
GII85_07660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII85_07665	COG1136	(ABC) transporter
GII85_07670	COG0577	efflux transmembrane transporter activity
GII85_07675	COG1349	DNA-binding transcription factor activity
GII85_07680	COG1105	Belongs to the carbohydrate kinase PfkB family
GII85_07685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII85_07685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII85_07685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII85_07690	COG0681	Belongs to the peptidase S26 family
GII85_07700	COG0488	(ABC) transporter
GII85_07705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII85_07710	COG2309	aminopeptidase activity
GII85_07720	COG1077	Cell shape determining protein MreB Mrl
GII85_07725	COG2002	toxin-antitoxin pair type II binding
GII85_07730	COG3852	Histidine kinase
GII85_07735	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII85_07735	COG2105	PFAM AIG2 family protein
GII85_07740	COG0569	domain protein
GII85_07745	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII85_07750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII85_07760	COG0561	phosphatase activity
GII85_07765	COG0242	peptide deformylase activity
GII85_07775	COG0497	DNA recombination
GII85_07780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII85_07785	COG0022	dehydrogenase e1 component
GII85_07790	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII85_07795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII85_07800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII85_07810	COG1982	Orn Lys Arg decarboxylase major
GII85_07815	COG4476	Belongs to the UPF0223 family
GII85_07820	COG4493	Belongs to the UPF0637 family
GII85_07830	COG0483	inositol monophosphate 1-phosphatase activity
GII85_07840	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII85_07890	COG4896	Protein conserved in bacteria
GII85_07900	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII85_07905	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII85_07910	COG2066	Belongs to the glutaminase family
GII85_07915	COG4838	Belongs to the UPF0358 family
GII85_07920	COG0772	Belongs to the SEDS family
GII85_07925	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII85_07930	COG1612	heme a metabolic process
GII85_07935	COG0109	protoheme IX farnesyltransferase activity
GII85_07940	COG2010	Cytochrome c
GII85_07940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII85_07945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII85_07950	COG1845	cytochrome c oxidase, subunit III
GII85_07955	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII85_07960	COG3336	cytochrome c oxidase
GII85_07970	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII85_07975	COG2340	Cysteine-rich secretory protein family
GII85_07990	COG3679	Belongs to the UPF0342 family
GII85_07995	COG4471	UPF0298 protein
GII85_08000	COG0742	ribosomal rna small subunit methyltransferase
GII85_08005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII85_08010	COG3314	Sporulation integral membrane protein YlbJ
GII85_08015	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII85_08020	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII85_08025	COG1323	Belongs to the UPF0348 family
GII85_08035	COG1399	metal-binding, possibly nucleic acid-binding protein
GII85_08040	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GII85_08050	COG0454	-acetyltransferase
GII85_08055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII85_08060	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII85_08065	COG2001	Belongs to the MraZ family
GII85_08070	COG0275	rRNA processing
GII85_08075	COG4839	cell division protein FtsL
GII85_08085	COG0768	penicillin binding
GII85_08090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII85_08095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII85_08100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII85_08105	COG0772	Belongs to the SEDS family
GII85_08110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII85_08115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII85_08120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII85_08125	COG3879	Bacterial protein of unknown function (DUF881)
GII85_08130	COG3879	Bacterial protein of unknown function (DUF881)
GII85_08135	COG3856	small basic protein
GII85_08140	COG0849	cell division
GII85_08145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII85_08150	COG4412	M6 family metalloprotease domain protein
GII85_08150	COG1404	Belongs to the peptidase S8 family
GII85_08160	COG1191	sigma factor activity
GII85_08165	COG1191	sigma factor activity
GII85_08170	COG1119	ATPase activity
GII85_08175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII85_08180	COG1873	PFAM PRC-barrel domain
GII85_08190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII85_08195	COG1799	cell septum assembly
GII85_08200	COG0762	integral membrane protein
GII85_08205	COG2302	S4 RNA-binding domain
GII85_08210	COG3599	regulation of cell shape
GII85_08215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII85_08220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII85_08225	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII85_08230	COG0564	pseudouridine synthase activity
GII85_08235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII85_08240	COG2233	PERMEase
GII85_08245	COG0540	Belongs to the ATCase OTCase family
GII85_08250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII85_08255	COG0505	Belongs to the CarA family
GII85_08260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII85_08265	COG0543	2 iron, 2 sulfur cluster binding
GII85_08270	COG0167	dihydroorotate dehydrogenase activity
GII85_08275	COG0284	orotidine-5'-phosphate decarboxylase activity
GII85_08280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII85_08285	COG0175	sulfate reduction
GII85_08290	COG0306	phosphate transporter
GII85_08295	COG2046	Belongs to the sulfate adenylyltransferase family
GII85_08300	COG0529	Catalyzes the synthesis of activated sulfate
GII85_08305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII85_08310	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII85_08315	COG1648	precorrin-2 dehydrogenase activity
GII85_08325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII85_08330	COG1561	YicC-like family, N-terminal region
GII85_08335	COG2052	Domain of unknown function (DUF370)
GII85_08340	COG0194	GDP metabolic process
GII85_08345	COG1758	RNA polymerase activity
GII85_08350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII85_08355	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII85_08360	COG0242	peptide deformylase activity
GII85_08365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII85_08370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII85_08370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII85_08375	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII85_08380	COG0631	protein serine/threonine phosphatase activity
GII85_08385	COG2815	serine threonine protein kinase
GII85_08385	COG0515	serine threonine protein kinase
GII85_08390	COG1162	GTPase activity
GII85_08395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII85_08400	COG1564	THIamine pyrophosphokinase
GII85_08410	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII85_08415	COG1302	Protein conserved in bacteria
GII85_08420	COG1461	Dihydroxyacetone kinase
GII85_08425	COG1760	l-serine dehydratase
GII85_08430	COG1760	l-serine dehydratase
GII85_08435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII85_08440	COG1349	DNA-binding transcription factor activity
GII85_08440	COG2050	protein possibly involved in aromatic compounds catabolism
GII85_08445	COG0416	fatty acid biosynthetic process
GII85_08450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII85_08455	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_08460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII85_08465	COG0571	ribonuclease III activity
GII85_08470	COG1196	nuclear chromosome segregation
GII85_08475	COG0552	protein localization to endoplasmic reticulum
GII85_08485	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII85_08490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII85_08495	COG0228	four-way junction DNA binding
GII85_08500	COG1837	Belongs to the UPF0109 family
GII85_08510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII85_08515	COG0336	Belongs to the RNA methyltransferase TrmD family
GII85_08520	COG0335	large ribosomal subunit rRNA binding
GII85_08525	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII85_08530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII85_08540	COG2257	FlhB HrpN YscU SpaS Family
GII85_08545	COG0045	succinate-CoA ligase (ADP-forming) activity
GII85_08550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII85_08555	COG0758	DNA mediated transformation
GII85_08560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII85_08565	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII85_08570	COG4974	Belongs to the 'phage' integrase family
GII85_08575	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII85_08580	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII85_08585	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII85_08590	COG1815	bacterial-type flagellum-dependent cell motility
GII85_08595	COG1558	bacterial-type flagellum-dependent cell motility
GII85_08600	COG1677	Flagellar hook-basal body complex protein FliE
GII85_08605	COG1766	The M ring may be actively involved in energy transduction
GII85_08610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII85_08615	COG1317	bacterial-type flagellum organization
GII85_08620	COG1157	protein secretion by the type III secretion system
GII85_08625	COG2882	bacterial-type flagellum organization
GII85_08630	COG3334	PFAM MgtE intracellular
GII85_08635	COG3144	bacterial-type flagellum assembly
GII85_08640	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII85_08645	COG4786	Flagellar basal body rod
GII85_08650	COG1582	Flagellar protein (FlbD)
GII85_08655	COG1580	Controls the rotational direction of flagella during chemotaxis
GII85_08660	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII85_08665	COG1776	CheC inhibitor of MCP methylation
GII85_08665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII85_08670	COG2201	protein-glutamate methylesterase activity
GII85_08675	COG3190	flagellar
GII85_08680	COG1338	Plays a role in the flagellum-specific transport system
GII85_08685	COG1987	bacterial-type flagellum assembly
GII85_08690	COG1684	flagellar biosynthetic protein fliR
GII85_08695	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII85_08700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII85_08705	COG1419	protein localization to endoplasmic reticulum
GII85_08710	COG0455	bacterial-type flagellum organization
GII85_08715	COG2201	protein-glutamate methylesterase activity
GII85_08720	COG0643	Histidine kinase
GII85_08720	COG2198	Histidine kinase
GII85_08725	COG0835	chemotaxis
GII85_08730	COG1776	CheC inhibitor of MCP methylation
GII85_08735	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII85_08740	COG1191	sigma factor activity
GII85_08750	COG0052	Belongs to the universal ribosomal protein uS2 family
GII85_08755	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII85_08760	COG0528	UMP kinase activity
GII85_08765	COG0233	cytoplasmic translational termination
GII85_08770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII85_08775	COG4589	Belongs to the CDS family
GII85_08780	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII85_08785	COG0750	zinc metalloprotease
GII85_08790	COG0442	prolyl-tRNA aminoacylation
GII85_08795	COG2176	DNA-directed DNA polymerase activity
GII85_08820	COG0779	Required for maturation of 30S ribosomal subunits
GII85_08825	COG0195	Participates in both transcription termination and antitermination
GII85_08830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII85_08835	COG1358	cellular component organization or biogenesis
GII85_08840	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII85_08845	COG1550	Protein conserved in bacteria
GII85_08850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII85_08855	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII85_08860	COG0196	riboflavin kinase activity
GII85_08865	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII85_08870	COG1185	polyribonucleotide nucleotidyltransferase activity
GII85_08875	COG0726	polysaccharide deacetylase
GII85_08880	COG0612	Peptidase, M16
GII85_08885	COG1873	PFAM PRC-barrel domain
GII85_08890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII85_08895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII85_08900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII85_08905	COG0527	aspartate kinase activity
GII85_08910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII85_08915	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII85_08920	COG0740	serine-type endopeptidase activity
GII85_08930	COG1674	ftsk spoiiie
GII85_08930	COG4980	gas vesicle protein
GII85_08935	COG2188	Transcriptional regulator
GII85_08940	COG2814	Major facilitator Superfamily
GII85_08945	COG0612	Peptidase, M16
GII85_08950	COG0612	Peptidase, M16
GII85_08955	COG0300	oxidoreductase activity
GII85_08970	COG1426	Protein conserved in bacteria
GII85_08975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII85_08980	COG1546	Belongs to the CinA family
GII85_08980	COG1058	Belongs to the CinA family
GII85_08985	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII85_08990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII85_08995	COG1418	mRNA catabolic process
GII85_09000	COG1692	metallophosphoesterase
GII85_09005	COG2359	stage V sporulation protein S
GII85_09010	COG1063	alcohol dehydrogenase
GII85_09015	COG0156	8-amino-7-oxononanoate synthase activity
GII85_09020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII85_09025	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII85_09035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII85_09040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII85_09055	COG3226	Transcriptional regulator
GII85_09060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII85_09070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII85_09075	COG3321	synthase
GII85_09080	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII85_09080	COG2070	2-Nitropropane dioxygenase
GII85_09085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII85_09090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII85_09095	COG3425	synthase
GII85_09100	COG1024	Enoyl-CoA hydratase
GII85_09105	COG1024	Enoyl-CoA hydratase
GII85_09110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_09110	COG0318	PFAM AMP-dependent synthetase and ligase
GII85_09110	COG0300	oxidoreductase activity
GII85_09110	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_09110	COG3321	synthase
GII85_09115	COG4221	oxidoreductase activity
GII85_09115	COG0300	oxidoreductase activity
GII85_09115	COG3321	synthase
GII85_09115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII85_09120	COG3321	synthase
GII85_09120	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_09120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII85_09120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_09120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII85_09125	COG4221	oxidoreductase activity
GII85_09125	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_09125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_09125	COG3321	synthase
GII85_09130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GII85_09130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII85_09130	COG3321	synthase
GII85_09130	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII85_09135	COG2124	cytochrome p450
GII85_09145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII85_09150	COG1404	Belongs to the peptidase S8 family
GII85_09160	COG4195	phage-related replication protein
GII85_09165	COG1764	response to oxidative stress
GII85_09170	COG2076	Multidrug Resistance protein
GII85_09175	COG2076	Multidrug Resistance protein
GII85_09190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII85_09195	COG1923	regulation of RNA biosynthetic process
GII85_09210	COG1780	Probably involved in ribonucleotide reductase function
GII85_09215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII85_09220	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII85_09225	COG4112	unkown
GII85_09230	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII85_09235	COG0464	growth
GII85_09240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII85_09245	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII85_09250	COG0789	Transcriptional regulator
GII85_09255	COG0174	glutamine synthetase
GII85_09280	COG4282	regulation of fungal-type cell wall biogenesis
GII85_09290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII85_09320	COG0135	phosphoribosylanthranilate isomerase activity
GII85_09325	COG2211	Major facilitator Superfamily
GII85_09330	COG3507	Belongs to the glycosyl hydrolase 43 family
GII85_09335	COG1940	carbohydrate kinase activity
GII85_09340	COG2115	Belongs to the xylose isomerase family
GII85_09345	COG1070	Carbohydrate kinase
GII85_09360	COG2814	Major facilitator Superfamily
GII85_09365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII85_09380	COG0756	dUTP diphosphatase activity
GII85_09420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII85_09435	COG3832	glyoxalase III activity
GII85_09445	COG0697	spore germination
GII85_09450	COG0531	amino acid
GII85_09480	COG4195	phage-related replication protein
GII85_09490	COG0346	lactoylglutathione lyase activity
GII85_09495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII85_09500	COG1388	LysM domain
GII85_09505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII85_09510	COG4224	UPF0291 protein
GII85_09515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII85_09525	COG3763	UPF0154 protein
GII85_09535	COG0785	Cytochrome C biogenesis protein
GII85_09540	COG2201	protein-glutamate methylesterase activity
GII85_09545	COG4846	Membrane protein involved in cytochrome C biogenesis
GII85_09555	COG0071	Belongs to the small heat shock protein (HSP20) family
GII85_09570	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII85_09575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII85_09595	COG0824	Thioesterase
GII85_09605	COG4841	protein insertion into membrane
GII85_09610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII85_09615	COG1832	CoA-binding protein
GII85_09620	COG0187	DNA topoisomerase II activity
GII85_09625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII85_09635	COG1115	amino acid carrier protein
GII85_09640	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GII85_09650	COG5520	Belongs to the glycosyl hydrolase 30 family
GII85_09655	COG3507	Belongs to the glycosyl hydrolase 43 family
GII85_09660	COG2246	polysaccharide biosynthetic process
GII85_09665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII85_09670	COG0586	Pfam SNARE associated Golgi protein
GII85_09675	COG2404	hydrolase activity, acting on ester bonds
GII85_09680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII85_09685	COG1024	Enoyl-CoA hydratase
GII85_09690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII85_09695	COG0511	ligase activity, forming carbon-carbon bonds
GII85_09700	COG0439	Biotin carboxylase
GII85_09705	COG0318	PFAM AMP-dependent synthetase and ligase
GII85_09710	COG1960	acyl-CoA dehydrogenase activity
GII85_09720	COG1649	PFAM Uncharacterised BCR, COG1649
GII85_09730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_09730	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII85_09735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_09740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_09745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_09750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_09755	COG2027	D-alanyl-D-alanine carboxypeptidase
GII85_09760	COG2017	converts alpha-aldose to the beta-anomer
GII85_09765	COG0534	Mate efflux family protein
GII85_09780	COG0582	viral genome integration into host DNA
GII85_09785	COG0166	Belongs to the GPI family
GII85_09790	COG0405	Gamma-glutamyltransferase
GII85_09795	COG0583	DNA-binding transcription factor activity
GII85_09805	COG0493	'glutamate synthase
GII85_09810	COG0067	glutamate synthase
GII85_09810	COG0070	glutamate synthase
GII85_09810	COG0069	glutamate synthase activity
GII85_09815	COG0583	DNA-binding transcription factor activity
GII85_09820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII85_09825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII85_09835	COG0300	oxidoreductase activity
GII85_09840	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII85_09850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII85_09865	COG1131	(ABC) transporter
GII85_09875	COG2814	Major facilitator Superfamily
GII85_09880	COG1070	Carbohydrate kinase
GII85_09885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII85_09890	COG0243	molybdopterin cofactor binding
GII85_09900	COG2814	Major facilitator Superfamily
GII85_09905	COG0673	inositol 2-dehydrogenase activity
GII85_09910	COG1082	Xylose isomerase domain protein TIM barrel
GII85_09915	COG1609	Transcriptional regulator
GII85_09935	COG0840	transmembrane signaling receptor activity
GII85_09935	COG5278	phosphoserine phosphatase activity
GII85_09940	COG2368	4-hydroxyphenylacetate
GII85_09945	COG4305	rare lipoprotein A
GII85_09950	COG3619	membrane
GII85_09955	COG3866	Pectate lyase
GII85_09960	COG2135	peptidase activity
GII85_09970	COG2140	Oxalate decarboxylase
GII85_09990	COG2720	vancomycin resistance protein
GII85_10005	COG3739	integral membrane protein
GII85_10010	COG0583	DNA-binding transcription factor activity
GII85_10015	COG0697	spore germination
GII85_10025	COG0693	protein deglycase activity
GII85_10030	COG2367	Beta-lactamase
GII85_10045	COG3848	Pyruvate phosphate dikinase
GII85_10045	COG0574	Belongs to the PEP-utilizing enzyme family
GII85_10050	COG0726	polysaccharide deacetylase
GII85_10055	COG2314	TM2 domain
GII85_10080	COG3655	Transcriptional regulator
GII85_10110	COG0457	Tetratricopeptide repeat
GII85_10120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII85_10130	COG4282	regulation of fungal-type cell wall biogenesis
GII85_10135	COG1231	oxidoreductase activity
GII85_10140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII85_10145	COG0662	Cupin 2, conserved barrel domain protein
GII85_10145	COG2207	Transcriptional regulator
GII85_10150	COG0456	acetyltransferase
GII85_10155	COG1309	transcriptional regulator
GII85_10160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII85_10165	COG3708	Transcriptional regulator
GII85_10170	COG2378	regulation of single-species biofilm formation
GII85_10180	COG0640	Transcriptional regulator
GII85_10185	COG0741	lytic transglycosylase activity
GII85_10190	COG2322	membrane
GII85_10205	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII85_10210	COG3239	Fatty acid desaturase
GII85_10215	COG4585	Histidine kinase
GII85_10220	COG2197	response regulator
GII85_10225	COG3584	3D domain protein
GII85_10225	COG1388	LysM domain
GII85_10230	COG0514	ATP-dependent DNA helicase (RecQ)
GII85_10240	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII85_10245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII85_10260	COG0071	Belongs to the small heat shock protein (HSP20) family
GII85_10285	COG1012	belongs to the aldehyde dehydrogenase family
GII85_10290	COG1657	PFAM Prenyltransferase squalene oxidase
GII85_10295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII85_10300	COG0733	neurotransmitter:sodium symporter activity
GII85_10305	COG0385	Bile acid
GII85_10310	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII85_10315	COG0567	Dehydrogenase, E1 component
GII85_10320	COG4548	von Willebrand factor, type A
GII85_10325	COG0714	Associated with various cellular activities
GII85_10330	COG2032	superoxide dismutase activity
GII85_10335	COG1388	LysM domain
GII85_10335	COG0791	NLP P60 protein
GII85_10340	COG1819	glycosyl
GII85_10345	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII85_10350	COG0534	Mate efflux family protein
GII85_10355	COG1366	Belongs to the anti-sigma-factor antagonist family
GII85_10360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII85_10365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII85_10375	COG2962	Rard protein
GII85_10390	COG2610	gluconate transmembrane transporter activity
GII85_10395	COG1942	4-Oxalocrotonate Tautomerase
GII85_10400	COG1733	regulation of RNA biosynthetic process
GII85_10405	COG0778	Nitroreductase
GII85_10410	COG0400	carboxylic ester hydrolase activity
GII85_10415	COG0346	lactoylglutathione lyase activity
GII85_10425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII85_10430	COG0793	Belongs to the peptidase S41A family
GII85_10430	COG3409	Peptidoglycan-binding domain 1 protein
GII85_10435	COG2226	methyltransferase
GII85_10445	COG1876	peptidase activity
GII85_10450	COG0813	purine-nucleoside phosphorylase activity
GII85_10465	COG0671	phosphoesterase, PA-phosphatase related
GII85_10485	COG4479	Belongs to the UPF0346 family
GII85_10495	COG1509	lysine 2,3-aminomutase activity
GII85_10500	COG0456	acetyltransferase
GII85_10505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII85_10510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII85_10515	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII85_10520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII85_10535	COG0456	acetyltransferase
GII85_10540	COG0463	Glycosyl transferase, family 2
GII85_10555	COG4641	Protein conserved in bacteria
GII85_10560	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII85_10565	COG1086	Polysaccharide biosynthesis protein
GII85_10570	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII85_10575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII85_10580	COG1846	Transcriptional regulator
GII85_10585	COG0534	Mate efflux family protein
GII85_10595	COG4698	Protein conserved in bacteria
GII85_10600	COG2755	lipolytic protein G-D-S-L family
GII85_10605	COG1999	signal sequence binding
GII85_10615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII85_10620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII85_10625	COG1272	protein, Hemolysin III
GII85_10630	COG0204	Acyl-transferase
GII85_10635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII85_10640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII85_10650	COG2136	Putative SAM-dependent methyltransferase
GII85_10650	COG2521	methyltransferase
GII85_10660	COG0129	dihydroxy-acid dehydratase activity
GII85_10665	COG1413	lyase activity
GII85_10670	COG1418	mRNA catabolic process
GII85_10675	COG0386	Belongs to the glutathione peroxidase family
GII85_10680	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII85_10685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII85_10695	COG1278	Cold shock
GII85_10715	COG0328	RNA-DNA hybrid ribonuclease activity
GII85_10720	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII85_10725	COG0328	RNA-DNA hybrid ribonuclease activity
GII85_10735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII85_10750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII85_10760	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII85_10765	COG3424	synthase
GII85_10770	COG2233	PERMEase
GII85_10775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII85_10780	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII85_10790	COG0800	Aldolase
GII85_10795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII85_10800	COG1609	Transcriptional regulator
GII85_10805	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII85_10810	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_10815	COG1199	ATP-dependent helicase activity
GII85_10830	COG0116	Belongs to the methyltransferase superfamily
GII85_10845	COG4474	Belongs to the UPF0398 family
GII85_10860	COG3359	exonuclease
GII85_10865	COG1205	dead DEAH box helicase
GII85_10865	COG1111	helicase
GII85_10870	COG2190	(PTS) system
GII85_10875	COG0071	Belongs to the small heat shock protein (HSP20) family
GII85_10910	COG3331	DNA recombination
GII85_10915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII85_10915	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII85_10925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII85_10930	COG3935	DnaD domain protein
GII85_10935	COG0017	Asparaginyl-tRNA synthetase
GII85_10940	COG0436	Aminotransferase
GII85_10945	COG5353	protein conserved in bacteria
GII85_10955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII85_10955	COG1199	ATP-dependent helicase activity
GII85_10960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII85_10965	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII85_10970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII85_10975	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII85_10975	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII85_10980	COG0617	tRNA 3'-terminal CCA addition
GII85_10985	COG0438	transferase activity, transferring glycosyl groups
GII85_10990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII85_10995	COG1803	Methylglyoxal synthase
GII85_11000	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII85_11005	COG1694	Mazg nucleotide pyrophosphohydrolase
GII85_11010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII85_11020	COG4347	Protein of unknown function (DUF1405)
GII85_11025	COG2010	Cytochrome c
GII85_11025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII85_11030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII85_11035	COG0723	plastoquinol--plastocyanin reductase activity
GII85_11045	COG5582	Belongs to the UPF0302 family
GII85_11050	COG0457	Tetratricopeptide repeat
GII85_11055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII85_11060	COG0287	Prephenate dehydrogenase
GII85_11065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GII85_11075	COG0133	tryptophan synthase activity
GII85_11080	COG0135	phosphoribosylanthranilate isomerase activity
GII85_11090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII85_11095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII85_11100	COG4401	Chorismate mutase type I
GII85_11105	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII85_11110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII85_11115	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII85_11120	COG0105	UTP biosynthetic process
GII85_11125	COG0142	geranyltranstransferase activity
GII85_11130	COG2226	methyltransferase
GII85_11135	COG0142	geranyltranstransferase activity
GII85_11145	COG0302	gtp cyclohydrolase
GII85_11150	COG0776	regulation of translation
GII85_11155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII85_11170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII85_11175	COG1160	GTP binding
GII85_11200	COG1304	FMN binding
GII85_11205	COG0539	negative regulation of cytoplasmic translation
GII85_11210	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII85_11220	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII85_11225	COG2959	enzyme of heme biosynthesis
GII85_11230	COG3773	Cell wall hydrolase
GII85_11230	COG3409	Peptidoglycan-binding domain 1 protein
GII85_11235	COG2339	peptidase activity
GII85_11240	COG0492	ferredoxin-NADP+ reductase activity
GII85_11245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII85_11250	COG4862	establishment of competence for transformation
GII85_11255	COG1408	metallophosphoesterase
GII85_11265	COG1388	LysM domain
GII85_11270	COG1266	CAAX protease self-immunity
GII85_11275	COG0514	ATP-dependent DNA helicase (RecQ)
GII85_11280	COG4955	Helix-turn-helix domain
GII85_11285	COG1141	Ferredoxin
GII85_11290	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII85_11295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII85_11300	COG0710	3-dehydroquinate dehydratase activity
GII85_11310	COG1595	DNA-templated transcription, initiation
GII85_11315	COG5002	protein histidine kinase activity
GII85_11320	COG0745	RESPONSE REGULATOR receiver
GII85_11325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII85_11330	COG1333	cytochrome c biogenesis protein
GII85_11335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII85_11340	COG1187	pseudouridine synthase activity
GII85_11345	COG0700	Nucleoside recognition
GII85_11350	COG2715	membrane protein required for spore maturation
GII85_11355	COG1686	Belongs to the peptidase S11 family
GII85_11365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII85_11370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII85_11375	COG1547	Domain of unknown function (DUF309)
GII85_11380	COG0456	acetyltransferase
GII85_11385	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII85_11390	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII85_11390	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII85_11395	COG0307	riboflavin synthase, alpha
GII85_11400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII85_11400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII85_11410	COG0681	Belongs to the peptidase S26 family
GII85_11425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII85_11435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII85_11470	COG0322	excinuclease ABC activity
GII85_11475	COG3584	3D domain protein
GII85_11520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII85_11545	COG1428	Deoxynucleoside kinase
GII85_11555	COG1435	thymidine kinase activity
GII85_11570	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GII85_11775	COG1598	PFAM Uncharacterised protein family UPF0150
GII85_11785	COG0457	Tetratricopeptide repeat
GII85_11795	COG4086	secreted protein
GII85_11800	COG0019	diaminopimelate decarboxylase activity
GII85_11805	COG0697	spore germination
GII85_11820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII85_11840	COG1191	sigma factor activity
GII85_11845	COG2172	sigma factor antagonist activity
GII85_11850	COG1366	Belongs to the anti-sigma-factor antagonist family
GII85_11855	COG1686	Belongs to the peptidase S11 family
GII85_11860	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII85_11865	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII85_11870	COG4974	Belongs to the 'phage' integrase family
GII85_11880	COG0735	belongs to the Fur family
GII85_11885	COG1300	Membrane
GII85_11895	COG0281	malic enzyme
GII85_11900	COG1757	Na H antiporter
GII85_11905	COG1027	Aspartate ammonia-lyase
GII85_11910	COG0252	asparaginase activity
GII85_11915	COG1396	sequence-specific DNA binding
GII85_11920	COG1379	DNA repair
GII85_11925	COG0494	nUDIX hydrolase
GII85_11935	COG0667	Aldo Keto reductase
GII85_11945	COG1073	alpha beta
GII85_11955	COG4918	Iron-sulphur cluster biosynthesis
GII85_11960	COG0456	acetyltransferase
GII85_11960	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII85_11965	COG2329	Antibiotic biosynthesis monooxygenase
GII85_11970	COG0456	acetyltransferase
GII85_11980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII85_11990	COG2211	Major facilitator Superfamily
GII85_11995	COG0346	lactoylglutathione lyase activity
GII85_12000	COG1072	(Pantothenic acid kinase))
GII85_12005	COG3048	D-serine ammonia-lyase activity
GII85_12010	COG0300	oxidoreductase activity
GII85_12015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII85_12020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII85_12025	COG4187	Peptidase family M20/M25/M40
GII85_12030	COG1902	pentaerythritol trinitrate reductase activity
GII85_12035	COG0596	Alpha beta hydrolase
GII85_12045	COG1234	tRNA 3'-trailer cleavage
GII85_12050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII85_12055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII85_12060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII85_12070	COG0706	membrane insertase activity
GII85_12075	COG3361	conserved protein (COG2071)
GII85_12080	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII85_12085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII85_12090	COG0346	lactoylglutathione lyase activity
GII85_12100	COG1376	ErfK ybiS ycfS ynhG family protein
GII85_12105	COG4129	membrane
GII85_12110	COG1126	abc transporter atp-binding protein
GII85_12115	COG0765	amino acid transport
GII85_12120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII85_12130	COG1597	lipid kinase activity
GII85_12135	COG2814	Major facilitator Superfamily
GII85_12140	COG4978	Transcriptional regulator
GII85_12140	COG0789	Transcriptional regulator
GII85_12145	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII85_12150	COG0022	dehydrogenase e1 component
GII85_12155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII85_12160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII85_12165	COG3426	butyrate kinase activity
GII85_12170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII85_12175	COG0280	phosphate acetyltransferase
GII85_12180	COG3290	protein histidine kinase activity
GII85_12180	COG3829	transcription factor binding
GII85_12190	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII85_12195	COG2079	MmgE PrpD family protein
GII85_12200	COG0372	Belongs to the citrate synthase family
GII85_12205	COG1960	acyl-CoA dehydrogenase activity
GII85_12210	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII85_12215	COG0183	Belongs to the thiolase family
GII85_12220	COG0584	glycerophosphoryl diester phosphodiesterase
GII85_12225	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII85_12240	COG1902	pentaerythritol trinitrate reductase activity
GII85_12245	COG0745	RESPONSE REGULATOR receiver
GII85_12250	COG0750	zinc metalloprotease
GII85_12255	COG0497	DNA recombination
GII85_12260	COG1438	arginine binding
GII85_12265	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII85_12270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII85_12275	COG0142	geranyltranstransferase activity
GII85_12280	COG1722	exodeoxyribonuclease VII activity
GII85_12285	COG1570	exodeoxyribonuclease VII activity
GII85_12290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII85_12295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII85_12300	COG1302	Protein conserved in bacteria
GII85_12305	COG0439	Biotin carboxylase
GII85_12310	COG0511	ligase activity, forming carbon-carbon bonds
GII85_12350	COG3854	ATPases associated with a variety of cellular activities
GII85_12360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII85_12365	COG0006	proline dipeptidase activity
GII85_12370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII85_12380	COG3872	metal-dependent enzyme
GII85_12390	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII85_12395	COG1321	iron dependent repressor
GII85_12400	COG0095	Lipoate-protein ligase
GII85_12405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII85_12410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII85_12415	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII85_12420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII85_12425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII85_12440	COG1396	sequence-specific DNA binding
GII85_12450	COG0681	Belongs to the peptidase S26 family
GII85_12475	COG4940	Competence protein ComGF
GII85_12485	COG4970	Tfp pilus assembly protein FimT
GII85_12490	COG4537	Required for transformation and DNA binding
GII85_12495	COG1459	type II secretion system
GII85_12500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII85_12505	COG0598	Magnesium transport protein CorA
GII85_12510	COG1253	flavin adenine dinucleotide binding
GII85_12515	COG1366	Belongs to the anti-sigma-factor antagonist family
GII85_12525	COG1393	Belongs to the ArsC family
GII85_12535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII85_12545	COG0011	TIGRFAM Protein of
GII85_12555	COG2866	Carboxypeptidase
GII85_12560	COG1368	sulfuric ester hydrolase activity
GII85_12565	COG1940	carbohydrate kinase activity
GII85_12570	COG4483	Protein conserved in bacteria
GII85_12575	COG0457	Tetratricopeptide repeat
GII85_12575	COG0705	Rhomboid family
GII85_12585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII85_12590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII85_12595	COG0438	transferase activity, transferring glycosyl groups
GII85_12610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII85_12615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII85_12620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII85_12625	COG0581	inorganic phosphate transmembrane transporter activity
GII85_12630	COG0573	inorganic phosphate transmembrane transporter activity
GII85_12635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII85_12645	COG0477	Major facilitator Superfamily
GII85_12650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII85_12655	COG2839	Protein conserved in bacteria
GII85_12660	COG5521	maltodextrose utilization protein MalA
GII85_12665	COG1388	LysM domain
GII85_12670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII85_12675	COG4709	membrane
GII85_12680	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII85_12685	COG0735	belongs to the Fur family
GII85_12690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII85_12700	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII85_12705	COG0513	Belongs to the DEAD box helicase family
GII85_12715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII85_12720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII85_12725	COG2384	SAM-dependent methyltransferase
GII85_12730	COG2010	Cytochrome c
GII85_12735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII85_12740	COG0358	DNA primase activity
GII85_12745	COG1671	Belongs to the UPF0178 family
GII85_12750	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII85_12755	COG0517	IMP dehydrogenase activity
GII85_12760	COG0751	glycine-tRNA ligase activity
GII85_12765	COG0752	glycyl-tRNA synthetase alpha subunit
GII85_12770	COG1381	Involved in DNA repair and RecF pathway recombination
GII85_12780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII85_12785	COG0295	cytidine deaminase activity
GII85_12790	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII85_12795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII85_12800	COG1480	7TM receptor with intracellular HD hydrolase
GII85_12805	COG1702	phosphate starvation-inducible protein PhoH
GII85_12810	COG0561	phosphatase activity
GII85_12825	COG4864	UPF0365 protein
GII85_12830	COG1030	water channel activity
GII85_12835	COG1610	YqeY-like protein
GII85_12840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GII85_12845	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII85_12850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII85_12855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII85_12860	COG2264	protein methyltransferase activity
GII85_12865	COG0484	heat shock protein binding
GII85_12870	COG0443	Heat shock 70 kDa protein
GII85_12875	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII85_12880	COG1420	regulation of RNA biosynthetic process
GII85_12885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII85_12890	COG0481	GTPase activity
GII85_12900	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII85_12905	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII85_12910	COG0268	Binds directly to 16S ribosomal RNA
GII85_12915	COG1466	dna polymerase III delta subunit
GII85_12930	COG2333	competence protein COMEC
GII85_12930	COG0658	competence protein
GII85_12935	COG2131	deaminase
GII85_12940	COG1596	polysaccharide export
GII85_12940	COG1555	photosystem II stabilization
GII85_12945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII85_12950	COG2226	methyltransferase
GII85_12955	COG0799	negative regulation of ribosome biogenesis
GII85_12960	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII85_12965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII85_12970	COG1534	Rna-binding protein
GII85_12975	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII85_12980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII85_12985	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII85_12995	COG2755	lipolytic protein G-D-S-L family
GII85_13000	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII85_13000	COG3409	Peptidoglycan-binding domain 1 protein
GII85_13005	COG0398	Pfam SNARE associated Golgi protein
GII85_13010	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GII85_13020	COG3209	COG3209 Rhs family protein
GII85_13035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII85_13045	COG3223	Belongs to the PsiE family
GII85_13050	COG5002	protein histidine kinase activity
GII85_13050	COG0642	Histidine kinase
GII85_13055	COG0745	RESPONSE REGULATOR receiver
GII85_13060	COG2311	Membrane
GII85_13070	COG0454	-acetyltransferase
GII85_13075	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII85_13085	COG0730	response to heat
GII85_13090	COG0425	Belongs to the sulfur carrier protein TusA family
GII85_13095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII85_13095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII85_13105	COG0425	Belongs to the sulfur carrier protein TusA family
GII85_13105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII85_13110	COG2210	Belongs to the sulfur carrier protein TusA family
GII85_13115	COG1937	Protein conserved in bacteria
GII85_13120	COG0662	Cupin 2, conserved barrel domain protein
GII85_13130	COG0789	Transcriptional regulator
GII85_13130	COG4978	Transcriptional regulator
GII85_13135	COG2814	Major facilitator Superfamily
GII85_13140	COG0456	acetyltransferase
GII85_13145	COG1253	flavin adenine dinucleotide binding
GII85_13155	COG0697	spore germination
GII85_13160	COG0583	DNA-binding transcription factor activity
GII85_13165	COG2072	flavoprotein involved in K transport
GII85_13170	COG1230	cation diffusion facilitator family transporter
GII85_13180	COG1114	Component of the transport system for branched-chain amino acids
GII85_13185	COG1687	branched-chain amino acid
GII85_13190	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII85_13195	COG1522	sequence-specific DNA binding
GII85_13200	COG2732	(Barnase) inhibitor
GII85_13205	COG2124	cytochrome p450
GII85_13215	COG1335	isochorismatase
GII85_13230	COG2318	DinB family
GII85_13240	COG2070	2-Nitropropane dioxygenase
GII85_13245	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII85_13255	COG2186	Transcriptional regulator
GII85_13270	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_13275	COG3958	Transketolase
GII85_13280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII85_13285	COG0477	Major facilitator Superfamily
GII85_13290	COG1846	Transcriptional regulator
GII85_13295	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII85_13300	COG1595	DNA-templated transcription, initiation
GII85_13305	COG0667	Aldo Keto reductase
GII85_13310	COG3409	Peptidoglycan-binding domain 1 protein
GII85_13315	COG5566	PFAM Mor transcription activator
GII85_13320	COG0596	Alpha beta hydrolase
GII85_13325	COG4991	sh3 domain protein
GII85_13330	COG4991	sh3 domain protein
GII85_13340	COG0346	lactoylglutathione lyase activity
GII85_13350	COG5577	PFAM Coat F domain
GII85_13355	COG1063	alcohol dehydrogenase
GII85_13365	COG5577	PFAM Coat F domain
GII85_13370	COG0789	Transcriptional regulator
GII85_13380	COG1064	alcohol dehydrogenase
GII85_13385	COG0693	protein deglycase activity
GII85_13390	COG1621	beta-fructofuranosidase activity
GII85_13395	COG3716	PTS system mannose fructose sorbose family IID component
GII85_13400	COG3715	PTS system
GII85_13405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII85_13410	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII85_13415	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII85_13415	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII85_13425	COG1113	amino acid transport
GII85_13430	COG1280	lysine exporter protein (LysE YggA)
GII85_13435	COG1378	Sugar-specific transcriptional regulator TrmB
GII85_13440	COG1595	DNA-templated transcription, initiation
GII85_13450	COG2755	lipolytic protein G-D-S-L family
GII85_13450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GII85_13460	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII85_13460	COG2124	cytochrome p450
GII85_13465	COG1309	transcriptional regulator
GII85_13470	COG2226	methyltransferase
GII85_13485	COG2116	formate transmembrane transporter activity
GII85_13490	COG5609	conserved protein (DUF2294)
GII85_13495	COG3383	formate dehydrogenase (NAD+) activity
GII85_13500	COG2427	Protein of unknown function (DUF1641)
GII85_13510	COG0626	cystathionine gamma-synthase activity
GII85_13515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII85_13520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII85_13525	COG2226	methyltransferase
GII85_13540	COG0768	penicillin binding
GII85_13545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII85_13550	COG0572	uridine kinase
GII85_13570	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII85_13575	COG3906	Belongs to the UPF0473 family
GII85_13580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII85_13585	COG4472	Bacterial protein of unknown function (DUF965)
GII85_13590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII85_13595	COG0628	permease
GII85_13600	COG1126	abc transporter atp-binding protein
GII85_13605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII85_13610	COG0765	amino acid transport
GII85_13615	COG0765	amino acid transport
GII85_13630	COG3881	PFAM PRC-barrel domain
GII85_13635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII85_13640	COG0457	Tetratricopeptide repeat
GII85_13645	COG0482	sulfurtransferase activity
GII85_13650	COG1104	cysteine desulfurase activity
GII85_13655	COG1959	2 iron, 2 sulfur cluster binding
GII85_13660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII85_13665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII85_13675	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII85_13680	COG0124	histidyl-tRNA synthetase
GII85_13690	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII85_13690	COG4991	sh3 domain protein
GII85_13690	COG3103	Sh3 type 3 domain protein
GII85_13695	COG1490	D-aminoacyl-tRNA deacylase activity
GII85_13700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII85_13705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII85_13710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII85_13710	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII85_13715	COG5416	Lipopolysaccharide assembly protein A domain
GII85_13720	COG0490	domain, Protein
GII85_13725	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII85_13725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII85_13735	COG2244	polysaccharide biosynthetic process
GII85_13740	COG2323	membrane
GII85_13750	COG1862	Preprotein translocase
GII85_13755	COG0343	queuine tRNA-ribosyltransferase activity
GII85_13760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII85_13770	COG2255	four-way junction helicase activity
GII85_13775	COG0632	four-way junction helicase activity
GII85_13785	COG2814	Major facilitator Superfamily
GII85_13790	COG0673	inositol 2-dehydrogenase activity
GII85_13795	COG2112	serine threonine protein kinase
GII85_13815	COG1115	amino acid carrier protein
GII85_13820	COG0217	transcriptional regulatory protein
GII85_13830	COG1388	LysM domain
GII85_13835	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII85_13840	COG0157	Belongs to the NadC ModD family
GII85_13845	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII85_13850	COG1104	cysteine desulfurase activity
GII85_13855	COG1827	regulation of RNA biosynthetic process
GII85_13860	COG0077	Prephenate dehydratase
GII85_13865	COG4492	Belongs to the UPF0735 family
GII85_13870	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII85_13875	COG3290	protein histidine kinase activity
GII85_13885	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII85_13890	COG2868	ribosomal protein
GII85_13895	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII85_13900	COG1994	Peptidase M50
GII85_13905	COG0739	heme binding
GII85_13910	COG2894	cell division
GII85_13915	COG0850	regulation of cytokinetic process
GII85_13920	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII85_13925	COG1792	Involved in formation and maintenance of cell shape
GII85_13930	COG1077	Cell shape determining protein MreB Mrl
GII85_13935	COG2003	Belongs to the UPF0758 family
GII85_13940	COG0424	maF-like protein
GII85_13950	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII85_13955	COG0285	dihydrofolate synthase activity
GII85_13960	COG0525	valine-tRNA ligase activity
GII85_13970	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII85_13975	COG1388	LysM domain
GII85_13980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII85_13985	COG0113	porphobilinogen synthase activity
GII85_13990	COG1587	Uroporphyrinogen-III synthase
GII85_13995	COG0181	hydroxymethylbilane synthase activity
GII85_14000	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII85_14005	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII85_14015	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII85_14020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII85_14025	COG0470	DNA polymerase III
GII85_14025	COG1067	ATP-dependent peptidase activity
GII85_14030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII85_14035	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII85_14040	COG1477	protein flavinylation
GII85_14040	COG0457	Tetratricopeptide repeat
GII85_14045	COG0066	3-isopropylmalate dehydratase activity
GII85_14050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII85_14055	COG0473	3-isopropylmalate dehydrogenase activity
GII85_14060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII85_14065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII85_14070	COG0440	acetolactate synthase activity
GII85_14075	COG0028	Belongs to the TPP enzyme family
GII85_14085	COG0454	-acetyltransferase
GII85_14090	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII85_14100	COG0622	Phosphoesterase
GII85_14105	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII85_14110	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII85_14115	COG5401	PFAM Sporulation and spore germination
GII85_14120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII85_14125	COG1846	Transcriptional regulator
GII85_14130	COG2197	response regulator
GII85_14135	COG0824	Thioesterase
GII85_14140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII85_14145	COG1053	succinate dehydrogenase
GII85_14150	COG2009	succinate dehydrogenase
GII85_14155	COG1719	4-vinyl reductase, 4VR
GII85_14160	COG0527	aspartate kinase activity
GII85_14165	COG0322	excinuclease ABC activity
GII85_14170	COG3118	belongs to the thioredoxin family
GII85_14175	COG3534	alpha-L-arabinofuranosidase
GII85_14180	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII85_14185	COG2086	electron transfer activity
GII85_14190	COG1024	Enoyl-CoA hydratase
GII85_14195	COG1309	transcriptional regulator
GII85_14200	COG0318	PFAM AMP-dependent synthetase and ligase
GII85_14205	COG3766	membrane
GII85_14210	COG1193	negative regulation of DNA recombination
GII85_14215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII85_14215	COG1796	DNA polymerase
GII85_14220	COG1286	toxin biosynthetic process
GII85_14225	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII85_14230	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII85_14235	COG0072	phenylalanine-tRNA ligase activity
GII85_14235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII85_14240	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII85_14250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII85_14260	COG3835	regulator
GII85_14265	COG0277	FAD linked oxidase domain protein
GII85_14270	COG0247	lactate metabolic process
GII85_14275	COG0346	lactoylglutathione lyase activity
GII85_14285	COG1966	Carbon starvation protein
GII85_14290	COG3534	alpha-L-arabinofuranosidase
GII85_14295	COG0395	ABC-type sugar transport system, permease component
GII85_14300	COG1175	transmembrane transport
GII85_14305	COG1653	transport
GII85_14310	COG0371	Dehydrogenase
GII85_14315	COG0647	UMP catabolic process
GII85_14320	COG0235	Class ii aldolase
GII85_14325	COG1069	ribulokinase activity
GII85_14330	COG2160	L-arabinose isomerase activity
GII85_14335	COG3507	Belongs to the glycosyl hydrolase 43 family
GII85_14340	COG1363	Peptidase, m42
GII85_14350	COG3326	Membrane
GII85_14355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII85_14360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII85_14365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII85_14375	COG1346	cytolysis
GII85_14380	COG1380	Effector of murein hydrolase LrgA
GII85_14385	COG3279	Response regulator of the LytR AlgR family
GII85_14390	COG3275	phosphorelay sensor kinase activity
GII85_14400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII85_14410	COG0398	Pfam SNARE associated Golgi protein
GII85_14415	COG1484	DNA-dependent DNA replication
GII85_14420	COG3611	Membrane attachment protein
GII85_14425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII85_14430	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII85_14435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII85_14440	COG1733	regulation of RNA biosynthetic process
GII85_14445	COG2814	Major facilitator Superfamily
GII85_14450	COG0656	L-ascorbic acid biosynthetic process
GII85_14455	COG0237	dephospho-CoA kinase activity
GII85_14460	COG1971	Probably functions as a manganese efflux pump
GII85_14465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII85_14470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII85_14470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII85_14475	COG5002	protein histidine kinase activity
GII85_14480	COG0745	RESPONSE REGULATOR receiver
GII85_14485	COG0039	L-malate dehydrogenase activity
GII85_14490	COG0538	isocitrate dehydrogenase activity
GII85_14495	COG0372	Belongs to the citrate synthase family
GII85_14500	COG2707	UPF0756 membrane protein
GII85_14505	COG0628	permease
GII85_14510	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII85_14515	COG0469	pyruvate kinase activity
GII85_14520	COG0205	6-phosphofructokinase activity
GII85_14525	COG0825	malonyl-CoA metabolic process
GII85_14530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII85_14535	COG0281	malic enzyme
GII85_14540	COG0587	DNA-directed DNA polymerase activity
GII85_14560	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII85_14570	COG4109	DRTGG domain
GII85_14575	COG0730	response to heat
GII85_14580	COG1473	amidohydrolase
GII85_14585	COG0196	riboflavin kinase activity
GII85_14590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII85_14595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII85_14600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII85_14605	COG1126	abc transporter atp-binding protein
GII85_14610	COG0765	amino acid transport
GII85_14615	COG0765	amino acid transport
GII85_14620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII85_14625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII85_14630	COG0454	-acetyltransferase
GII85_14635	COG0583	DNA-binding transcription factor activity
GII85_14640	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII85_14645	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_14655	COG0165	Argininosuccinate lyase
GII85_14660	COG0137	argininosuccinate synthase activity
GII85_14665	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII85_14670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII85_14680	COG0827	DNA restriction-modification system
GII85_14685	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII85_14690	COG3874	Sporulation protein YtfJ
GII85_14700	COG1714	RDD family
GII85_14705	COG0616	signal peptide processing
GII85_14710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII85_14715	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII85_14720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII85_14730	COG0301	tRNA thio-modification
GII85_14735	COG1104	cysteine desulfurase activity
GII85_14740	COG1114	Component of the transport system for branched-chain amino acids
GII85_14745	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII85_14750	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII85_14755	COG1309	transcriptional regulator
GII85_14760	COG1956	GAF domain-containing protein
GII85_14765	COG2199	diguanylate cyclase activity
GII85_14765	COG2203	Gaf domain
GII85_14775	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII85_14780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII85_14785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII85_14790	COG0454	-acetyltransferase
GII85_14795	COG0517	IMP dehydrogenase activity
GII85_14800	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII85_14805	COG1360	Flagellar Motor Protein
GII85_14810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII85_14815	COG1609	Transcriptional regulator
GII85_14820	COG1605	Chorismate mutase
GII85_14820	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII85_14825	COG3118	belongs to the thioredoxin family
GII85_14830	COG4980	gas vesicle protein
GII85_14835	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII85_14840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII85_14845	COG1674	ftsk spoiiie
GII85_14850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII85_14855	COG4848	Belongs to the UPF0354 family
GII85_14860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII85_14875	COG1363	Peptidase, m42
GII85_14880	COG5584	Small secreted protein
GII85_14885	COG0281	malic enzyme
GII85_14890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII85_14895	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII85_14905	COG0510	thiamine kinase activity
GII85_14910	COG1523	belongs to the glycosyl hydrolase 13 family
GII85_14915	COG1597	lipid kinase activity
GII85_14925	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII85_14930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII85_14935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII85_14940	COG2252	PERMEase
GII85_14945	COG4473	ABC transporter
GII85_14950	COG1131	(ABC) transporter
GII85_14955	COG1349	DNA-binding transcription factor activity
GII85_14960	COG1187	pseudouridine synthase activity
GII85_14965	COG2244	polysaccharide biosynthetic process
GII85_14970	COG2081	HI0933 family
GII85_14975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII85_14985	COG5578	integral membrane protein
GII85_14990	COG0673	inositol 2-dehydrogenase activity
GII85_14995	COG1653	transport
GII85_15000	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII85_15005	COG4209	transmembrane transport
GII85_15010	COG2207	Transcriptional regulator
GII85_15015	COG1653	transport
GII85_15020	COG0395	ABC-type sugar transport system, permease component
GII85_15025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII85_15030	COG2124	cytochrome p450
GII85_15035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII85_15045	COG0156	8-amino-7-oxononanoate synthase activity
GII85_15050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII85_15060	COG1073	alpha beta
GII85_15085	COG1486	melibiose metabolic process
GII85_15090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII85_15095	COG0495	leucyl-tRNA aminoacylation
GII85_15105	COG2202	Pas domain
GII85_15105	COG1366	Belongs to the anti-sigma-factor antagonist family
GII85_15110	COG2814	Major facilitator Superfamily
GII85_15115	COG2433	Pfam Transposase IS66
GII85_15120	COG0577	efflux transmembrane transporter activity
GII85_15125	COG1136	(ABC) transporter
GII85_15130	COG2205	protein histidine kinase activity
GII85_15135	COG0745	RESPONSE REGULATOR receiver
GII85_15140	COG0577	efflux transmembrane transporter activity
GII85_15145	COG1136	(ABC) transporter
GII85_15160	COG1131	(ABC) transporter
GII85_15165	COG1725	Transcriptional regulator
GII85_15180	COG1242	4 iron, 4 sulfur cluster binding
GII85_15185	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII85_15195	COG2267	carboxylic ester hydrolase activity
GII85_15200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII85_15205	COG1113	amino acid transport
GII85_15210	COG0367	asparagine synthase
GII85_15215	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII85_15220	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII85_15230	COG1506	peptidase
GII85_15235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII85_15240	COG1116	anion transmembrane transporter activity
GII85_15245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII85_15250	COG0494	nUDIX hydrolase
GII85_15255	COG4824	toxin secretion phage lysis holin
GII85_15260	COG0783	Belongs to the Dps family
GII85_15275	COG1854	S-ribosylhomocysteine lyase activity
GII85_15280	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII85_15285	COG0288	reversible hydration of carbon dioxide
GII85_15290	COG0254	rRNA binding
GII85_15295	COG1271	oxidase subunit
GII85_15300	COG1294	oxidase, subunit
GII85_15310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII85_15315	COG1321	iron dependent repressor
GII85_15315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII85_15320	COG1121	(ABC) transporter
GII85_15325	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII85_15330	COG4948	Mandelate Racemase Muconate Lactonizing
GII85_15335	COG0318	PFAM AMP-dependent synthetase and ligase
GII85_15340	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII85_15345	COG0596	Alpha beta hydrolase
GII85_15350	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII85_15355	COG1169	isochorismate synthase
GII85_15360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII85_15365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII85_15370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII85_15375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII85_15380	COG0438	transferase activity, transferring glycosyl groups
GII85_15390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII85_15395	COG0438	transferase activity, transferring glycosyl groups
GII85_15400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII85_15405	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GII85_15410	COG0058	SHG alpha-glucan phosphorylase activity
GII85_15415	COG0297	glycogen (starch) synthase activity
GII85_15420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII85_15425	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII85_15430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII85_15555	COG3859	Proton-coupled thiamine transporter YuaJ
GII85_15560	COG1247	-acetyltransferase
GII85_15565	COG2268	Band 7 protein
GII85_15570	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII85_15575	COG2318	DinB family
GII85_15585	COG1454	alcohol dehydrogenase
GII85_15595	COG1510	regulation of RNA biosynthetic process
GII85_15605	COG0569	domain protein
GII85_15610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII85_15615	COG4682	membrane
GII85_15620	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII85_15625	COG0477	Major facilitator Superfamily
GII85_15630	COG5553	Cysteine dioxygenase type I
GII85_15640	COG1968	undecaprenyl-diphosphatase activity
GII85_15645	COG0628	permease
GII85_15650	COG0673	inositol 2-dehydrogenase activity
GII85_15655	COG4806	L-rhamnose isomerase
GII85_15660	COG3254	rhamnose metabolic process
GII85_15665	COG1070	Carbohydrate kinase
GII85_15670	COG1349	DNA-binding transcription factor activity
GII85_15675	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_15675	COG3347	Dehydrogenase
GII85_15680	COG0840	transmembrane signaling receptor activity
GII85_15685	COG0840	transmembrane signaling receptor activity
GII85_15690	COG0840	transmembrane signaling receptor activity
GII85_15695	COG0840	transmembrane signaling receptor activity
GII85_15710	COG0432	Pfam Uncharacterised protein family UPF0047
GII85_15720	COG0366	Alpha amylase catalytic
GII85_15725	COG1253	flavin adenine dinucleotide binding
GII85_15730	COG2738	Putative neutral zinc metallopeptidase
GII85_15745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII85_15760	COG0166	Belongs to the GPI family
GII85_15765	COG1979	alcohol dehydrogenase
GII85_15770	COG1979	alcohol dehydrogenase
GII85_15775	COG2155	Conserved Protein
GII85_15780	COG1098	S1 RNA binding domain
GII85_15785	COG0436	Aminotransferase
GII85_15790	COG1522	sequence-specific DNA binding
GII85_15795	COG2267	carboxylic ester hydrolase activity
GII85_15805	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII85_15810	COG2205	protein histidine kinase activity
GII85_15820	COG5018	Exonuclease
GII85_15830	COG2814	Major facilitator Superfamily
GII85_15835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII85_15840	COG3011	Protein conserved in bacteria
GII85_15850	COG3290	protein histidine kinase activity
GII85_15855	COG4565	transcriptional regulatory protein
GII85_15880	COG3493	citrate carrier protein
GII85_15890	COG2111	Na H antiporter
GII85_15890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII85_15895	COG2111	Na H antiporter
GII85_15900	COG1006	Multisubunit Na H antiporter MnhC subunit
GII85_15905	COG0651	ATP synthesis coupled electron transport
GII85_15910	COG1863	multisubunit Na H antiporter MnhE subunit
GII85_15915	COG2212	antiporter activity
GII85_15920	COG1320	monovalent cation:proton antiporter activity
GII85_15925	COG2050	protein possibly involved in aromatic compounds catabolism
GII85_15930	COG2197	response regulator
GII85_15935	COG4585	Histidine kinase
GII85_15945	COG0142	geranyltranstransferase activity
GII85_15960	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII85_15965	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII85_15970	COG1335	isochorismatase
GII85_15975	COG5506	Protein of unknown function (DUF1694)
GII85_15990	COG0628	permease
GII85_16005	COG1418	mRNA catabolic process
GII85_16010	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_16020	COG1511	domain protein
GII85_16025	COG1674	ftsk spoiiie
GII85_16025	COG0433	COG0433 Predicted ATPase
GII85_16030	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII85_16035	COG5417	Belongs to the EsaB family
GII85_16040	COG4842	Belongs to the WXG100 family
GII85_16045	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII85_16045	COG2508	Transcriptional regulator
GII85_16050	COG0686	Belongs to the AlaDH PNT family
GII85_16055	COG5634	Uncharacterized conserved protein (DUF2278)
GII85_16060	COG3251	PFAM MbtH domain protein
GII85_16065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_16070	COG3433	isochorismatase activity
GII85_16070	COG1535	isochorismatase
GII85_16075	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII85_16080	COG1169	isochorismate synthase
GII85_16085	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_16090	COG2819	hydrolase of the alpha beta superfamily
GII85_16095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII85_16100	COG1268	BioY protein
GII85_16105	COG2056	Na+-H+ antiporter family
GII85_16110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII85_16115	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII85_16120	COG3584	3D domain protein
GII85_16135	COG1252	NADH dehydrogenase
GII85_16140	COG0492	ferredoxin-NADP+ reductase activity
GII85_16150	COG0516	GMP reductase activity
GII85_16155	COG2808	Putative FMN-binding domain
GII85_16160	COG0456	acetyltransferase
GII85_16165	COG0316	Belongs to the HesB IscA family
GII85_16170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII85_16175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII85_16180	COG4844	belongs to the
GII85_16185	COG1252	NADH dehydrogenase
GII85_16190	COG4837	Protein of unknown function (DUF1462)
GII85_16195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII85_16200	COG4946	Tricorn protease homolog
GII85_16200	COG0823	Involved in the tonB-independent uptake of proteins
GII85_16200	COG1506	peptidase
GII85_16205	COG0083	homoserine kinase activity
GII85_16210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII85_16215	COG0460	homoserine dehydrogenase
GII85_16220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII85_16225	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII85_16230	COG0647	UMP catabolic process
GII85_16235	COG2445	Protein of unknown function DUF86
GII85_16240	COG4470	Protein conserved in bacteria
GII85_16250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII85_16255	COG0739	heme binding
GII85_16265	COG3377	Domain of unknown function (DUF1805)
GII85_16270	COG0737	Belongs to the 5'-nucleotidase family
GII85_16275	COG0730	response to heat
GII85_16280	COG1801	Protein of unknown function DUF72
GII85_16290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII85_16295	COG2508	Transcriptional regulator
GII85_16300	COG2233	PERMEase
GII85_16305	COG2233	PERMEase
GII85_16310	COG3195	allantoin biosynthetic process
GII85_16310	COG3648	Uricase
GII85_16315	COG2351	hydroxyisourate hydrolase activity
GII85_16325	COG2080	2 iron, 2 sulfur cluster binding
GII85_16330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII85_16335	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII85_16340	COG2068	MobA-Related Protein
GII85_16345	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII85_16350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII85_16355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII85_16365	COG2356	endonuclease I
GII85_16370	COG3842	ATPase activity
GII85_16375	COG2188	Transcriptional regulator
GII85_16385	COG0395	ABC-type sugar transport system, permease component
GII85_16390	COG1175	transmembrane transport
GII85_16395	COG1653	transport
GII85_16400	COG2222	sugar isomerase
GII85_16405	COG0322	excinuclease ABC activity
GII85_16410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII85_16425	COG0346	lactoylglutathione lyase activity
GII85_16430	COG0640	Transcriptional regulator
GII85_16435	COG0719	Fe-S assembly protein
GII85_16440	COG0822	iron-sulfur transferase activity
GII85_16445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII85_16450	COG0719	Fe-S assembly protein
GII85_16455	COG0396	ATPase activity
GII85_16465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII85_16470	COG1464	Belongs to the NlpA lipoprotein family
GII85_16475	COG2011	ABC-type metal ion transport system permease component
GII85_16480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII85_16490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII85_16495	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII85_16505	COG0509	glycine decarboxylation via glycine cleavage system
GII85_16510	COG1393	Belongs to the ArsC family
GII85_16515	COG1960	acyl-CoA dehydrogenase activity
GII85_16520	COG0183	Belongs to the thiolase family
GII85_16525	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII85_16525	COG1024	Enoyl-CoA hydratase
GII85_16535	COG0506	proline dehydrogenase activity
GII85_16545	COG5577	PFAM Coat F domain
GII85_16550	COG1846	Transcriptional regulator
GII85_16555	COG0477	Major facilitator Superfamily
GII85_16560	COG1942	4-Oxalocrotonate Tautomerase
GII85_16565	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_16570	COG0583	DNA-binding transcription factor activity
GII85_16580	COG1120	ATPase activity
GII85_16595	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_16600	COG0783	Belongs to the Dps family
GII85_16605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII85_16610	COG0745	RESPONSE REGULATOR receiver
GII85_16615	COG2205	protein histidine kinase activity
GII85_16615	COG2770	Histidine kinase
GII85_16625	COG1309	transcriptional regulator
GII85_16630	COG0114	fumarate hydratase activity
GII85_16640	COG0697	spore germination
GII85_16645	COG0814	amino acid
GII85_16655	COG2197	response regulator
GII85_16660	COG4585	Histidine kinase
GII85_16665	COG4758	membrane
GII85_16670	COG3595	metallopeptidase activity
GII85_16675	COG1842	Phage shock protein A
GII85_16680	COG4758	membrane
GII85_16685	COG2814	Major facilitator Superfamily
GII85_16690	COG2096	Adenosyltransferase
GII85_16695	COG1120	ATPase activity
GII85_16700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII85_16705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII85_16710	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_16715	COG3386	PFAM SMP-30 Gluconolaconase
GII85_16720	COG2205	protein histidine kinase activity
GII85_16725	COG0745	RESPONSE REGULATOR receiver
GII85_16735	COG1191	sigma factor activity
GII85_16745	COG2140	Oxalate decarboxylase
GII85_16755	COG0577	efflux transmembrane transporter activity
GII85_16760	COG1136	(ABC) transporter
GII85_16765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII85_16770	COG1120	ATPase activity
GII85_16775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII85_16780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII85_16785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII85_16790	COG0531	amino acid
GII85_16800	COG1988	membrane-bound metal-dependent
GII85_16805	COG1368	sulfuric ester hydrolase activity
GII85_16810	COG1910	domain protein
GII85_16815	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII85_16820	COG4149	molybdate abc transporter
GII85_16825	COG0656	L-ascorbic acid biosynthetic process
GII85_16835	COG0025	NhaP-type Na H and K H
GII85_16840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII85_16845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII85_16850	COG3973	AAA domain
GII85_16860	COG2860	membrane
GII85_16865	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII85_16870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII85_16875	COG2217	Heavy metal translocating P-type atpase
GII85_16880	COG2217	Heavy metal translocating P-type atpase
GII85_16885	COG2608	mercury ion transmembrane transporter activity
GII85_16890	COG1937	Protein conserved in bacteria
GII85_16895	COG0673	inositol 2-dehydrogenase activity
GII85_16900	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII85_16905	COG1289	transmembrane transporter activity
GII85_16915	COG2076	Multidrug Resistance protein
GII85_16920	COG1309	transcriptional regulator
GII85_16925	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_16950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII85_16955	COG0557	exoribonuclease II activity
GII85_16960	COG1647	Serine aminopeptidase, S33
GII85_16965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII85_16970	COG0596	Alpha beta hydrolase
GII85_16975	COG1476	TRANSCRIPTIONal
GII85_16980	COG1396	sequence-specific DNA binding
GII85_16985	COG1396	sequence-specific DNA binding
GII85_16990	COG1733	regulation of RNA biosynthetic process
GII85_16995	COG0840	transmembrane signaling receptor activity
GII85_17050	COG1174	glycine betaine transport
GII85_17055	COG1732	Glycine betaine
GII85_17060	COG1174	glycine betaine transport
GII85_17065	COG1125	glycine betaine transport
GII85_17065	COG0517	IMP dehydrogenase activity
GII85_17070	COG1510	regulation of RNA biosynthetic process
GII85_17075	COG1174	glycine betaine transport
GII85_17080	COG1732	Glycine betaine
GII85_17085	COG1174	glycine betaine transport
GII85_17090	COG1125	glycine betaine transport
GII85_17090	COG0517	IMP dehydrogenase activity
GII85_17095	COG1510	regulation of RNA biosynthetic process
GII85_17100	COG2095	MarC family integral membrane protein
GII85_17110	COG3064	Membrane
GII85_17115	COG4640	response to antibiotic
GII85_17120	COG0456	acetyltransferase
GII85_17125	COG0148	phosphopyruvate hydratase activity
GII85_17130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII85_17135	COG0149	triose-phosphate isomerase activity
GII85_17140	COG0126	phosphoglycerate kinase activity
GII85_17145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII85_17150	COG2390	Transcriptional regulator
GII85_17155	COG2814	Major facilitator Superfamily
GII85_17160	COG1609	Transcriptional regulator
GII85_17165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII85_17170	COG0583	DNA-binding transcription factor activity
GII85_17175	COG0697	spore germination
GII85_17180	COG1113	amino acid transport
GII85_17185	COG3858	chitin binding
GII85_17190	COG1556	Lactate utilization protein
GII85_17195	COG1139	Iron-sulfur cluster binding protein
GII85_17200	COG0247	lactate metabolic process
GII85_17205	COG2197	response regulator
GII85_17210	COG4585	Histidine kinase
GII85_17215	COG0842	Transport permease protein
GII85_17220	COG1131	(ABC) transporter
GII85_17225	COG0596	Alpha beta hydrolase
GII85_17230	COG2208	phosphoserine phosphatase activity
GII85_17235	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII85_17240	COG1874	Beta-galactosidase
GII85_17245	COG3833	ABC-type maltose transport systems, permease component
GII85_17250	COG1175	transmembrane transport
GII85_17255	COG2182	Extracellular solute-binding protein
GII85_17260	COG1609	Transcriptional regulator
GII85_17265	COG2186	Transcriptional regulator
GII85_17270	COG1620	l-lactate permease
GII85_17275	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII85_17285	COG5039	Polysaccharide pyruvyl transferase
GII85_17290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII85_17295	COG0110	maltose O-acetyltransferase activity
GII85_17300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII85_17305	COG2244	polysaccharide biosynthetic process
GII85_17310	COG1216	Glycosyl transferase, family 2
GII85_17315	COG5039	Polysaccharide pyruvyl transferase
GII85_17320	COG1216	Glycosyl transferase, family 2
GII85_17330	COG0438	transferase activity, transferring glycosyl groups
GII85_17335	COG1215	transferase activity, transferring glycosyl groups
GII85_17340	COG0438	transferase activity, transferring glycosyl groups
GII85_17345	COG1086	Polysaccharide biosynthesis protein
GII85_17350	COG0489	protein tyrosine kinase activity
GII85_17355	COG3944	biosynthesis protein
GII85_17360	COG1396	sequence-specific DNA binding
GII85_17365	COG2272	Belongs to the type-B carboxylesterase lipase family
GII85_17375	COG3479	Phenolic acid decarboxylase
GII85_17385	COG1794	racemase activity, acting on amino acids and derivatives
GII85_17390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII85_17395	COG1621	beta-fructofuranosidase activity
GII85_17400	COG1621	beta-fructofuranosidase activity
GII85_17405	COG0531	amino acid
GII85_17410	COG1309	transcriptional regulator
GII85_17415	COG2076	Multidrug Resistance protein
GII85_17420	COG2076	Multidrug Resistance protein
GII85_17435	COG0740	serine-type endopeptidase activity
GII85_17440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII85_17445	COG0366	Alpha amylase catalytic
GII85_17450	COG1554	hydrolase, family 65, central catalytic
GII85_17455	COG5521	maltodextrose utilization protein MalA
GII85_17460	COG3833	ABC-type maltose transport systems, permease component
GII85_17465	COG1175	transmembrane transport
GII85_17470	COG2182	Extracellular solute-binding protein
GII85_17475	COG0366	Alpha amylase catalytic
GII85_17480	COG1609	Transcriptional regulator
GII85_17485	COG1611	Belongs to the LOG family
GII85_17490	COG1694	Mazg nucleotide pyrophosphohydrolase
GII85_17495	COG0659	secondary active sulfate transmembrane transporter activity
GII85_17500	COG0288	reversible hydration of carbon dioxide
GII85_17505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII85_17510	COG0577	efflux transmembrane transporter activity
GII85_17515	COG1136	(ABC) transporter
GII85_17520	COG5002	protein histidine kinase activity
GII85_17525	COG0745	RESPONSE REGULATOR receiver
GII85_17540	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII85_17545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII85_17550	COG1481	regulation of sporulation
GII85_17555	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII85_17560	COG1660	Displays ATPase and GTPase activities
GII85_17565	COG1051	belongs to the nudix hydrolase family
GII85_17570	COG0492	ferredoxin-NADP+ reductase activity
GII85_17575	COG0791	NLP P60 protein
GII85_17575	COG3883	PFAM NLP P60 protein
GII85_17580	COG0457	Tetratricopeptide repeat
GII85_17585	COG1132	(ABC) transporter
GII85_17605	COG0140	phosphoribosyl-ATP diphosphatase activity
GII85_17605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII85_17610	COG0107	imidazoleglycerol-phosphate synthase activity
GII85_17615	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII85_17620	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII85_17625	COG0131	Imidazoleglycerol-phosphate dehydratase
GII85_17630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII85_17635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII85_17640	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII85_17645	COG4990	cell redox homeostasis
GII85_17650	COG5297	Belongs to the glycosyl hydrolase family 6
GII85_17655	COG0110	maltose O-acetyltransferase activity
GII85_17660	COG0546	phosphoglycolate phosphatase activity
GII85_17665	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII85_17670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII85_17675	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII85_17680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII85_17685	COG0363	glucosamine-6-phosphate deaminase activity
GII85_17695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII85_17700	COG1846	Transcriptional regulator
GII85_17715	COG1846	Transcriptional regulator
GII85_17720	COG2814	Major facilitator Superfamily
GII85_17725	COG1950	PFAM Membrane protein of
GII85_17730	COG1983	PspC domain protein
GII85_17735	COG3595	metallopeptidase activity
GII85_17755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII85_17760	COG0556	nucleotide-excision repair
GII85_17765	COG4897	Protein conserved in bacteria
GII85_17770	COG0574	Belongs to the PEP-utilizing enzyme family
GII85_17770	COG3848	Pyruvate phosphate dikinase
GII85_17775	COG1309	transcriptional regulator
GII85_17780	COG2814	Major facilitator Superfamily
GII85_17785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII85_17795	COG0793	Belongs to the peptidase S41A family
GII85_17795	COG3409	Peptidoglycan-binding domain 1 protein
GII85_17800	COG2177	Part of the ABC transporter FtsEX involved in
GII85_17805	COG2884	Cell division ATP-binding protein ftsE
GII85_17810	COG2010	Cytochrome c
GII85_17815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII85_17825	COG0653	protein targeting
GII85_17830	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII85_17845	COG1516	flagellar protein fliS
GII85_17850	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII85_17855	COG1334	flagellar protein FlaG
GII85_17860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII85_17865	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII85_17870	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII85_17880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII85_17885	COG1256	bacterial-type flagellum assembly
GII85_17885	COG4786	Flagellar basal body rod
GII85_17890	COG3418	PFAM FlgN family protein
GII85_17895	COG2747	anti-sigma28 factor FlgM
GII85_17905	COG1040	competence protein
GII85_17915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII85_17920	COG1307	EDD domain protein, DegV family
GII85_17925	COG2197	response regulator
GII85_17930	COG4585	Histidine kinase
GII85_17935	COG1739	Uncharacterized protein family UPF0029
GII85_17940	COG1316	TRANSCRIPTIONal
GII85_17945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII85_17950	COG0438	transferase activity, transferring glycosyl groups
GII85_17955	COG1215	transferase activity, transferring glycosyl groups
GII85_17960	COG3206	protein involved in exopolysaccharide biosynthesis
GII85_17965	COG3307	-O-antigen
GII85_17970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII85_17975	COG0297	glycogen (starch) synthase activity
GII85_17975	COG0438	transferase activity, transferring glycosyl groups
GII85_17980	COG2244	polysaccharide biosynthetic process
GII85_17995	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII85_17995	COG2247	cell wall binding repeat
GII85_18000	COG2247	cell wall binding repeat
GII85_18000	COG2385	sporulation resulting in formation of a cellular spore
GII85_18010	COG1316	TRANSCRIPTIONal
GII85_18015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII85_18035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII85_18040	COG1134	teichoic acid transport
GII85_18045	COG1682	transport, permease protein
GII85_18050	COG1215	transferase activity, transferring glycosyl groups
GII85_18050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII85_18055	COG0463	Glycosyl transferase, family 2
GII85_18100	COG4193	domain, Protein
GII85_18105	COG1482	cell wall glycoprotein biosynthetic process
GII85_18110	COG0697	spore germination
GII85_18115	COG0814	amino acid
GII85_18125	COG2814	Major facilitator Superfamily
GII85_18130	COG1316	TRANSCRIPTIONal
GII85_18135	COG0561	phosphatase activity
GII85_18140	COG0791	NLP P60 protein
GII85_18150	COG2843	Capsule synthesis protein
GII85_18160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII85_18165	COG1609	Transcriptional regulator
GII85_18170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII85_18175	COG1869	D-ribose catabolic process
GII85_18180	COG1129	ABC transporter
GII85_18185	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII85_18190	COG1879	ABC-type sugar transport system periplasmic component
GII85_18195	COG3103	Sh3 type 3 domain protein
GII85_18205	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII85_18210	COG3527	Alpha-acetolactate decarboxylase
GII85_18215	COG0028	Belongs to the TPP enzyme family
GII85_18220	COG0583	DNA-binding transcription factor activity
GII85_18225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII85_18240	COG5337	Spore coat protein CotH
GII85_18250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII85_18260	COG0405	Gamma-glutamyltransferase
GII85_18265	COG1522	sequence-specific DNA binding
GII85_18270	COG2059	Chromate
GII85_18275	COG2059	Chromate
GII85_18290	COG5444	nuclease activity
GII85_18310	COG3878	Protein conserved in bacteria
GII85_18315	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII85_18320	COG4464	protein tyrosine phosphatase activity
GII85_18325	COG0489	protein tyrosine kinase activity
GII85_18330	COG3944	biosynthesis protein
GII85_18340	COG4715	Zinc finger, swim domain protein
GII85_18345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII85_18350	COG0561	phosphatase activity
GII85_18355	COG1349	DNA-binding transcription factor activity
GII85_18360	COG0629	single-stranded DNA binding
GII85_18375	COG3764	Sortase (surface protein transpeptidase)
GII85_18385	COG3279	Response regulator of the LytR AlgR family
GII85_18390	COG2972	Histidine kinase
GII85_18390	COG0745	RESPONSE REGULATOR receiver
GII85_18395	COG1970	mechanosensitive ion channel activity
GII85_18400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII85_18405	COG0457	Tetratricopeptide repeat
GII85_18410	COG4786	Flagellar basal body rod
GII85_18415	COG4786	Flagellar basal body rod
GII85_18420	COG1077	Cell shape determining protein MreB Mrl
GII85_18425	COG1609	Transcriptional regulator
GII85_18435	COG1846	Transcriptional regulator
GII85_18440	COG2814	Major facilitator Superfamily
GII85_18445	COG3420	alginic acid biosynthetic process
GII85_18450	COG1953	Uracil, thiamine, allantoin
GII85_18455	COG0477	Major facilitator Superfamily
GII85_18460	COG1335	isochorismatase
GII85_18470	COG0004	ammonium transporteR
GII85_18475	COG0347	Belongs to the P(II) protein family
GII85_18480	COG0671	phosphoesterase, PA-phosphatase related
GII85_18490	COG0739	heme binding
GII85_18495	COG1247	-acetyltransferase
GII85_18515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII85_18520	COG0789	Transcriptional regulator
GII85_18530	COG2910	NAD(P)H-binding
GII85_18535	COG1959	2 iron, 2 sulfur cluster binding
GII85_18540	COG0804	urea catabolic process
GII85_18545	COG0832	Belongs to the urease beta subunit family
GII85_18550	COG0831	urea catabolic process
GII85_18565	COG3237	CsbD-like
GII85_18570	COG1994	Peptidase M50
GII85_18575	COG0457	Tetratricopeptide repeat
GII85_18580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII85_18585	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII85_18595	COG2304	oxidoreductase activity
GII85_18605	COG2304	oxidoreductase activity
GII85_18610	COG2385	sporulation resulting in formation of a cellular spore
GII85_18615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII85_18625	COG4836	Membrane
GII85_18635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII85_18640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII85_18645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII85_18650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII85_18655	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII85_18660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII85_18665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII85_18670	COG0356	it plays a direct role in the translocation of protons across the membrane
GII85_18680	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII85_18685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII85_18690	COG4475	Protein of unknown function (DUF436)
GII85_18695	COG0698	ribose 5-phosphate isomerase
GII85_18700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII85_18705	COG1971	Probably functions as a manganese efflux pump
GII85_18710	COG0009	L-threonylcarbamoyladenylate synthase
GII85_18715	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII85_18735	COG2890	protein-(glutamine-N5) methyltransferase activity
GII85_18740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII85_18745	COG0346	lactoylglutathione lyase activity
GII85_18750	COG0789	Transcriptional regulator
GII85_18755	COG0679	Auxin Efflux Carrier
GII85_18760	COG0281	malic enzyme
GII85_18765	COG1435	thymidine kinase activity
GII85_18770	COG0254	rRNA binding
GII85_18775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII85_18785	COG1494	fructose-1,6-bisphosphatase
GII85_18790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII85_18795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII85_18800	COG0191	fructose-bisphosphate aldolase activity
GII85_18805	COG2204	response regulator
GII85_18810	COG4821	SIS domain
GII85_18815	COG0504	CTP synthase activity
GII85_18820	COG3343	RNA polymerase activity
GII85_18825	COG1960	acyl-CoA dehydrogenase activity
GII85_18830	COG2181	nitrate reductase activity
GII85_18830	COG0247	lactate metabolic process
GII85_18835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII85_18840	COG4294	response to UV
GII85_18850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII85_18855	COG1132	(ABC) transporter
GII85_18860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII85_18870	COG2181	nitrate reductase activity
GII85_18875	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GII85_18880	COG1140	nitrate reductase beta subunit
GII85_18885	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII85_18890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII85_18900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII85_18905	COG2223	nitrite transmembrane transporter activity
GII85_18910	COG0018	arginyl-trna synthetase
GII85_18915	COG4506	Protein conserved in bacteria
GII85_18930	COG0535	radical SAM domain protein
GII85_18940	COG1131	(ABC) transporter
GII85_18945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII85_18950	COG0612	Peptidase, M16
GII85_18955	COG0612	Peptidase, M16
GII85_18965	COG3391	amine dehydrogenase activity
GII85_18970	COG3391	amine dehydrogenase activity
GII85_18980	COG0457	Tetratricopeptide repeat
GII85_18995	COG0010	Belongs to the arginase family
GII85_19000	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII85_19005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII85_19020	COG1994	Peptidase M50
GII85_19025	COG1942	4-Oxalocrotonate Tautomerase
GII85_19030	COG1846	Transcriptional regulator
GII85_19035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII85_19040	COG0477	Major facilitator Superfamily
GII85_19045	COG1959	2 iron, 2 sulfur cluster binding
GII85_19050	COG3465	dGTPase activity
GII85_19055	COG1078	dGTPase activity
GII85_19060	COG4844	belongs to the
GII85_19070	COG0697	spore germination
GII85_19075	COG0095	Lipoate-protein ligase
GII85_19080	COG0583	DNA-binding transcription factor activity
GII85_19085	COG0280	phosphate acetyltransferase
GII85_19095	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_19100	COG0436	Aminotransferase
GII85_19105	COG2814	Major facilitator Superfamily
GII85_19110	COG0151	Belongs to the GarS family
GII85_19115	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_19120	COG1917	Cupin 2, conserved barrel domain protein
GII85_19125	COG0077	Prephenate dehydratase
GII85_19130	COG2814	Major facilitator Superfamily
GII85_19135	COG0833	amino acid
GII85_19140	COG4187	Peptidase family M20/M25/M40
GII85_19145	COG1012	belongs to the aldehyde dehydrogenase family
GII85_19150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII85_19160	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII85_19165	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII85_19170	COG1088	dTDP-glucose 4,6-dehydratase activity
GII85_19175	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII85_19180	COG3980	spore coat polysaccharide biosynthesis protein
GII85_19185	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII85_19190	COG2089	acid synthase
GII85_19195	COG0456	acetyltransferase
GII85_19200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII85_19205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII85_19210	COG0463	Glycosyl transferase, family 2
GII85_19220	COG2363	Small membrane protein
GII85_19225	COG2233	PERMEase
GII85_19235	COG1012	belongs to the aldehyde dehydrogenase family
GII85_19240	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII85_19245	COG1216	Glycosyl transferase, family 2
GII85_19260	COG1695	Transcriptional regulator
GII85_19265	COG0351	phosphomethylpyrimidine kinase
GII85_19275	COG1621	beta-fructofuranosidase activity
GII85_19280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII85_19280	COG1263	PTS System
GII85_19285	COG2116	formate transmembrane transporter activity
GII85_19290	COG3711	transcriptional antiterminator
GII85_19300	COG1404	Belongs to the peptidase S8 family
GII85_19305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII85_19310	COG0778	Nitroreductase
GII85_19315	COG0772	Belongs to the SEDS family
GII85_19325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII85_19330	COG1845	cytochrome c oxidase, subunit III
GII85_19335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII85_19340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII85_19345	COG2261	transglycosylase associated protein
GII85_19350	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII85_19355	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII85_19360	COG2246	polysaccharide biosynthetic process
GII85_19365	COG1309	transcriptional regulator
GII85_19375	COG3162	membrane
GII85_19380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII85_19385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII85_19390	COG2837	iron assimilation
GII85_19395	COG2822	iron ion transport
GII85_19400	COG0672	)-iron permease
GII85_19405	COG0352	thiamine-phosphate diphosphorylase activity
GII85_19410	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII85_19415	COG0583	DNA-binding transcription factor activity
GII85_19420	COG1380	Effector of murein hydrolase LrgA
GII85_19425	COG1346	cytolysis
GII85_19430	COG2814	Major facilitator Superfamily
GII85_19435	COG4895	conserved protein (DUF2196)
GII85_19440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII85_19445	COG0346	lactoylglutathione lyase activity
GII85_19460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII85_19465	COG1404	Belongs to the peptidase S8 family
GII85_19470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII85_19470	COG1263	PTS System
GII85_19475	COG3711	transcriptional antiterminator
GII85_19480	COG1442	glycosyl transferase family 8
GII85_19485	COG5522	Integral membrane protein (intg_mem_TP0381)
GII85_19490	COG1846	Transcriptional regulator
GII85_19495	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII85_19500	COG2234	aminopeptidase activity
GII85_19515	COG2814	Major facilitator Superfamily
GII85_19520	COG2357	RelA SpoT domain protein
GII85_19525	COG1575	Belongs to the MenA family. Type 1 subfamily
GII85_19540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII85_19545	COG1696	Membrane protein involved in D-alanine export
GII85_19550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII85_19555	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII85_19560	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII85_19565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII85_19570	COG1486	melibiose metabolic process
GII85_19575	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII85_19580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII85_19585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII85_19590	COG3711	transcriptional antiterminator
GII85_19590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII85_19600	COG2094	Belongs to the DNA glycosylase MPG family
GII85_19605	COG0753	catalase activity
GII85_19610	COG2814	Major facilitator Superfamily
GII85_19615	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII85_19620	COG1131	(ABC) transporter
GII85_19640	COG1595	DNA-templated transcription, initiation
GII85_19645	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII85_19650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII85_19655	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII85_19660	COG4988	ABC transporter
GII85_19665	COG1294	oxidase, subunit
GII85_19670	COG1271	oxidase subunit
GII85_19675	COG3493	citrate carrier protein
GII85_19680	COG0501	Belongs to the peptidase M48B family
GII85_19690	COG0726	polysaccharide deacetylase
GII85_19705	COG3842	ATPase activity
GII85_19710	COG2508	Transcriptional regulator
GII85_19715	COG1012	belongs to the aldehyde dehydrogenase family
GII85_19720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII85_19730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII85_19735	COG1881	PFAM PEBP family protein
GII85_19740	COG0583	DNA-binding transcription factor activity
GII85_19750	COG4585	Histidine kinase
GII85_19755	COG2197	response regulator
GII85_19760	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII85_19770	COG4894	glucomannan catabolic process
GII85_19775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII85_19780	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII85_19785	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_19790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII85_19795	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII85_19800	COG2610	gluconate transmembrane transporter activity
GII85_19805	COG0500	methyltransferase
GII85_19810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII85_19825	COG0693	protein deglycase activity
GII85_19825	COG0753	catalase activity
GII85_19830	COG2851	Citrate transporter
GII85_19835	COG2273	Hydrolase Family 16
GII85_19840	COG3711	transcriptional antiterminator
GII85_19850	COG2270	Major facilitator Superfamily
GII85_19855	COG0513	Belongs to the DEAD box helicase family
GII85_19860	COG3401	FG-GAP repeat protein
GII85_19860	COG2755	lipolytic protein G-D-S-L family
GII85_19905	COG3209	COG3209 Rhs family protein
GII85_19910	COG0697	spore germination
GII85_19915	COG0589	response to stress
GII85_19920	COG2723	6-phospho-beta-galactosidase activity
GII85_19925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII85_19925	COG1263	PTS System
GII85_19925	COG2190	(PTS) system
GII85_19970	COG3507	Belongs to the glycosyl hydrolase 43 family
GII85_19985	COG2986	histidine ammonia-lyase
GII85_19990	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII85_19995	COG1228	amidohydrolase
GII85_20000	COG0010	Belongs to the arginase family
GII85_20005	COG0833	amino acid
GII85_20010	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII85_20015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII85_20020	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII85_20025	COG2390	Transcriptional regulator
GII85_20035	COG3192	ethanolamine utilization protein
GII85_20040	COG2079	MmgE PrpD family protein
GII85_20050	COG1126	abc transporter atp-binding protein
GII85_20055	COG0765	amino acid transport
GII85_20060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII85_20075	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII85_20080	COG0561	phosphatase activity
GII85_20110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII85_20115	COG5294	Protein conserved in bacteria
GII85_20120	COG0577	efflux transmembrane transporter activity
GII85_20125	COG1136	(ABC) transporter
GII85_20130	COG2205	protein histidine kinase activity
GII85_20135	COG0745	RESPONSE REGULATOR receiver
GII85_20140	COG0191	fructose-bisphosphate aldolase activity
GII85_20145	COG1082	Xylose isomerase domain protein TIM barrel
GII85_20150	COG1082	Xylose isomerase domain protein TIM barrel
GII85_20155	COG0673	inositol 2-dehydrogenase activity
GII85_20160	COG2814	Major facilitator Superfamily
GII85_20165	COG1082	Xylose isomerase domain protein TIM barrel
GII85_20170	COG3962	Belongs to the TPP enzyme family
GII85_20175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII85_20185	COG1012	belongs to the aldehyde dehydrogenase family
GII85_20190	COG1349	DNA-binding transcription factor activity
GII85_20195	COG0667	Aldo Keto reductase
GII85_20210	COG2814	Major facilitator Superfamily
GII85_20215	COG0326	Molecular chaperone. Has ATPase activity
GII85_20225	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_20250	COG1309	transcriptional regulator
GII85_20255	COG1012	belongs to the aldehyde dehydrogenase family
GII85_20260	COG1714	RDD family
GII85_20265	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GII85_20275	COG1714	RDD family
GII85_20280	COG2311	Membrane
GII85_20285	COG1917	Cupin 2, conserved barrel domain protein
GII85_20290	COG1309	transcriptional regulator
GII85_20295	COG1028	Short-chain dehydrogenase reductase Sdr
GII85_20300	COG1846	Transcriptional regulator
GII85_20305	COG1380	Effector of murein hydrolase LrgA
GII85_20310	COG1346	cytolysis
GII85_20315	COG5039	Polysaccharide pyruvyl transferase
GII85_20320	COG1929	Belongs to the glycerate kinase type-1 family
GII85_20325	COG1802	Transcriptional regulator
GII85_20330	COG1070	Carbohydrate kinase
GII85_20335	COG2610	gluconate transmembrane transporter activity
GII85_20340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII85_20345	COG0450	alkyl hydroperoxide reductase
GII85_20350	COG3634	alkyl hydroperoxide reductase activity
GII85_20360	COG2723	6-phospho-beta-galactosidase activity
GII85_20375	COG2188	Transcriptional regulator
GII85_20390	COG1131	(ABC) transporter
GII85_20395	COG1994	Peptidase M50
GII85_20400	COG0535	radical SAM domain protein
GII85_20410	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII85_20435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII85_20450	COG1063	alcohol dehydrogenase
GII85_20470	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII85_20475	COG0456	acetyltransferase
GII85_20480	COG0457	Tetratricopeptide repeat
GII85_20490	COG0010	Belongs to the arginase family
GII85_20495	COG0833	amino acid
GII85_20500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII85_20505	COG3829	transcription factor binding
GII85_20520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII85_20525	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII85_20530	COG4853	Protein conserved in bacteria
GII85_20535	COG4863	YycH protein
GII85_20540	COG5002	protein histidine kinase activity
GII85_20545	COG0745	RESPONSE REGULATOR receiver
GII85_20575	COG0346	lactoylglutathione lyase activity
GII85_20580	COG0305	Participates in initiation and elongation during chromosome replication
GII85_20595	COG3093	addiction module antidote protein HigA
GII85_20600	COG2807	transmembrane transport
GII85_20605	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII85_20610	COG0359	binds to the 23S rRNA
GII85_20615	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII85_20620	COG4241	membrane
GII85_20630	COG5577	PFAM Coat F domain
GII85_20635	COG1733	regulation of RNA biosynthetic process
GII85_20640	COG1227	inorganic diphosphatase activity
GII85_20650	COG2271	Major facilitator Superfamily
GII85_20655	COG0789	Transcriptional regulator
GII85_20655	COG4978	Transcriptional regulator
GII85_20665	COG4319	ketosteroid isomerase
GII85_20670	COG1357	PFAM Pentapeptide repeats (8 copies)
GII85_20675	COG2814	Major facilitator Superfamily
GII85_20680	COG0583	DNA-binding transcription factor activity
GII85_20685	COG2153	protein acetylation
GII85_20695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII85_20700	COG1846	Transcriptional regulator
GII85_20705	COG2153	protein acetylation
GII85_20710	COG2364	Membrane
GII85_20715	COG0456	acetyltransferase
GII85_20720	COG2315	Protein conserved in bacteria
GII85_20725	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII85_20745	COG0789	Transcriptional regulator
GII85_20750	COG0697	spore germination
GII85_20755	COG1331	Highly conserved protein containing a thioredoxin domain
GII85_20760	COG1266	CAAX protease self-immunity
GII85_20765	COG0477	Major facilitator Superfamily
GII85_20765	COG2814	Major facilitator Superfamily
GII85_20770	COG0110	maltose O-acetyltransferase activity
GII85_20775	COG0346	lactoylglutathione lyase activity
GII85_20780	COG1609	Transcriptional regulator
GII85_20785	COG0708	Exodeoxyribonuclease III
GII85_20790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII85_20795	COG0629	single-stranded DNA binding
GII85_20800	COG0360	Binds together with S18 to 16S ribosomal RNA
GII85_20805	COG0012	GTP binding
GII85_20810	COG0243	molybdopterin cofactor binding
GII85_20815	COG4481	Protein conserved in bacteria
GII85_20820	COG3949	Membrane
GII85_20830	COG1475	DNA binding
GII85_20835	COG1192	Involved in chromosome partitioning
GII85_20845	COG1475	DNA binding
GII85_20850	COG0357	Ribosomal RNA small subunit methyltransferase G
GII85_20855	COG0445	tRNA wobble uridine modification
GII85_20860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII85_20865	COG1847	R3H domain protein
GII85_20870	COG0706	membrane insertase activity
GII85_20875	COG0594	ribonuclease P activity
GII85_20880	COG0230	Belongs to the bacterial ribosomal protein bL34 family