locus-tag	class	description
GII87_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII87_00010	COG0592	DNA-directed DNA polymerase activity
GII87_00015	COG2501	S4 domain
GII87_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII87_00030	COG0187	DNA topoisomerase II activity
GII87_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII87_00070	COG0517	IMP dehydrogenase activity
GII87_00070	COG0516	GMP reductase activity
GII87_00075	COG1686	Belongs to the peptidase S11 family
GII87_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII87_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII87_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII87_00100	COG1428	Deoxynucleoside kinase
GII87_00105	COG1428	Deoxynucleoside kinase
GII87_00110	COG3858	chitin binding
GII87_00110	COG1388	LysM domain
GII87_00115	COG1335	isochorismatase
GII87_00120	COG0590	tRNA wobble adenosine to inosine editing
GII87_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII87_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII87_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII87_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII87_00190	COG3853	Toxic anion resistance protein (TelA)
GII87_00195	COG1982	Orn Lys Arg decarboxylase major
GII87_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII87_00205	COG3870	Protein conserved in bacteria
GII87_00210	COG1728	Protein conserved in bacteria
GII87_00215	COG0470	DNA polymerase III
GII87_00220	COG1774	PSP1 C-terminal conserved region
GII87_00225	COG4467	Involved in initiation control of chromosome replication
GII87_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII87_00235	COG2827	Endonuclease containing a URI domain
GII87_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII87_00245	COG2002	toxin-antitoxin pair type II binding
GII87_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII87_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII87_00255	COG0084	hydrolase, TatD family'
GII87_00260	COG3583	domain protein
GII87_00260	COG3584	3D domain protein
GII87_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII87_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII87_00280	COG4466	Protein conserved in bacteria
GII87_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII87_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII87_00300	COG0251	oxidation-reduction process
GII87_00305	COG2088	sporulation resulting in formation of a cellular spore
GII87_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII87_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII87_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII87_00325	COG0193	aminoacyl-tRNA hydrolase activity
GII87_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII87_00340	COG2002	toxin-antitoxin pair type II binding
GII87_00345	COG2244	polysaccharide biosynthetic process
GII87_00350	COG3956	TIGRFAM MazG family protein
GII87_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII87_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII87_00375	COG1098	S1 RNA binding domain
GII87_00390	COG2208	phosphoserine phosphatase activity
GII87_00395	COG2304	oxidoreductase activity
GII87_00400	COG0515	serine threonine protein kinase
GII87_00405	COG0037	tRNA processing
GII87_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII87_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII87_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII87_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII87_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII87_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII87_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII87_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII87_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII87_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII87_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII87_00470	COG1396	sequence-specific DNA binding
GII87_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII87_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII87_00560	COG4463	regulation of RNA biosynthetic process
GII87_00565	COG3880	PFAM UvrB UvrC protein
GII87_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII87_00575	COG0542	response to heat
GII87_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII87_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII87_00590	COG4956	integral membrane protein (PIN domain superfamily)
GII87_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII87_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII87_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII87_00610	COG1045	serine acetyltransferase
GII87_00615	COG0215	cysteine-tRNA ligase activity
GII87_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII87_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII87_00630	COG3688	RNA-binding protein containing a PIN domain
GII87_00635	COG1595	DNA-templated transcription, initiation
GII87_00640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII87_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII87_00650	COG0250	Participates in transcription elongation, termination and antitermination
GII87_00655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GII87_00660	COG0081	regulation of translation
GII87_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII87_00670	COG0222	ribosome binding
GII87_00675	COG2813	Specifically methylates the guanine in position
GII87_00680	COG0085	RNA polymerase activity
GII87_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII87_00690	COG1358	cellular component organization or biogenesis
GII87_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII87_00700	COG0049	tRNA binding
GII87_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII87_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII87_00715	COG0596	Alpha beta hydrolase
GII87_00720	COG0051	transcription antitermination factor activity, RNA binding
GII87_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII87_00730	COG0088	Forms part of the polypeptide exit tunnel
GII87_00735	COG0089	rRNA binding
GII87_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII87_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GII87_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GII87_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GII87_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII87_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
GII87_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII87_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII87_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII87_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII87_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII87_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII87_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII87_00815	COG1841	ribosomal large subunit assembly
GII87_00820	COG0200	Binds to the 23S rRNA
GII87_00825	COG0201	protein transport
GII87_00830	COG0563	adenylate kinase activity
GII87_00835	COG0024	Methionine aminopeptidase
GII87_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII87_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GII87_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII87_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII87_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII87_00865	COG0202	RNA polymerase activity
GII87_00870	COG0203	ribosomal protein L17
GII87_00875	COG1122	ATPase activity
GII87_00880	COG1122	ATPase activity
GII87_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII87_00890	COG0101	tRNA pseudouridine synthase activity
GII87_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII87_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII87_00905	COG2226	methyltransferase
GII87_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII87_00920	COG0489	protein tyrosine kinase activity
GII87_00930	COG2194	sulfuric ester hydrolase activity
GII87_00935	COG0726	polysaccharide deacetylase
GII87_01020	COG0659	secondary active sulfate transmembrane transporter activity
GII87_01025	COG0385	Bile acid
GII87_01030	COG2819	hydrolase of the alpha beta superfamily
GII87_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII87_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII87_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII87_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII87_01050	COG2207	Transcriptional regulator
GII87_01055	COG3876	Protein conserved in bacteria
GII87_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
GII87_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII87_01070	COG1263	PTS System
GII87_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_01075	COG1737	Transcriptional regulator
GII87_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII87_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII87_01090	COG1683	Conserved Protein
GII87_01120	COG1595	DNA-templated transcription, initiation
GII87_01125	COG5662	AntiSigma factor
GII87_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII87_01135	COG4856	YbbR-like protein
GII87_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII87_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII87_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII87_01160	COG2169	Transcriptional regulator
GII87_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII87_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII87_01175	COG3002	Belongs to the UPF0753 family
GII87_01180	COG0288	reversible hydration of carbon dioxide
GII87_01190	COG5609	conserved protein (DUF2294)
GII87_01195	COG0640	Transcriptional regulator
GII87_01200	COG2814	Major facilitator Superfamily
GII87_01205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII87_01215	COG0535	radical SAM domain protein
GII87_01220	COG1266	CAAX protease self-immunity
GII87_01225	COG1131	(ABC) transporter
GII87_01235	COG1413	lyase activity
GII87_01240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_01245	COG0596	Alpha beta hydrolase
GII87_01250	COG0745	RESPONSE REGULATOR receiver
GII87_01255	COG0642	Histidine kinase
GII87_01265	COG0515	serine threonine protein kinase
GII87_01280	COG1113	amino acid transport
GII87_01295	COG2602	Beta-lactamase
GII87_01300	COG2124	cytochrome p450
GII87_01310	COG0531	amino acid
GII87_01315	COG0584	glycerophosphoryl diester phosphodiesterase
GII87_01320	COG2271	Major facilitator Superfamily
GII87_01330	COG1846	Transcriptional regulator
GII87_01330	COG0456	acetyltransferase
GII87_01335	COG2271	Major facilitator Superfamily
GII87_01350	COG3409	Peptidoglycan-binding domain 1 protein
GII87_01355	COG0697	spore germination
GII87_01360	COG2207	Transcriptional regulator
GII87_01360	COG1917	Cupin 2, conserved barrel domain protein
GII87_01365	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII87_01370	COG3591	Belongs to the peptidase S1B family
GII87_01380	COG0596	Alpha beta hydrolase
GII87_01385	COG1183	phosphatidylcholine synthase activity
GII87_01390	COG0586	Pfam SNARE associated Golgi protein
GII87_01395	COG0688	phosphatidylethanolamine metabolic process
GII87_01405	COG2312	Erythromycin esterase
GII87_01410	COG2207	Transcriptional regulator
GII87_01420	COG1301	dicarboxylic acid transport
GII87_01425	COG1263	PTS System
GII87_01425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_01425	COG2190	(PTS) system
GII87_01430	COG0363	glucosamine-6-phosphate deaminase activity
GII87_01445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII87_01450	COG0833	amino acid
GII87_01455	COG2040	homocysteine
GII87_01465	COG1115	amino acid carrier protein
GII87_01470	COG2066	Belongs to the glutaminase family
GII87_01475	COG4191	Histidine kinase
GII87_01480	COG0784	Response regulator, receiver
GII87_01485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII87_01490	COG1012	belongs to the aldehyde dehydrogenase family
GII87_01495	COG2271	Major facilitator Superfamily
GII87_01500	COG4948	Mandelate Racemase Muconate Lactonizing
GII87_01505	COG2186	Transcriptional regulator
GII87_01510	COG2721	sulfolactate sulfo-lyase activity
GII87_01515	COG3173	Aminoglycoside phosphotransferase
GII87_01525	COG0697	spore germination
GII87_01530	COG0745	RESPONSE REGULATOR receiver
GII87_01535	COG2205	protein histidine kinase activity
GII87_01540	COG1131	(ABC) transporter
GII87_01560	COG3773	Cell wall hydrolase
GII87_01565	COG2304	oxidoreductase activity
GII87_01575	COG3540	Alkaline phosphatase
GII87_01580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII87_01585	COG0805	protein transport
GII87_01590	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII87_01595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII87_01600	COG0477	Major facilitator Superfamily
GII87_01605	COG1309	transcriptional regulator
GII87_01610	COG0252	asparaginase activity
GII87_01615	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII87_01620	COG1714	RDD family
GII87_01625	COG1405	negative regulation of cell septum assembly
GII87_01625	COG3012	SEC-C Motif Domain Protein
GII87_01630	COG3290	protein histidine kinase activity
GII87_01635	COG3279	Response regulator of the LytR AlgR family
GII87_01640	COG4555	ABC transporter
GII87_01645	COG1668	transmembrane transport
GII87_01650	COG0667	Aldo Keto reductase
GII87_01665	COG1595	DNA-templated transcription, initiation
GII87_01670	COG1595	DNA-templated transcription, initiation
GII87_01675	COG1876	peptidase activity
GII87_01680	COG0457	Tetratricopeptide repeat
GII87_01685	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_01690	COG0366	Alpha amylase catalytic
GII87_01695	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII87_01700	COG1121	(ABC) transporter
GII87_01705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII87_01710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII87_01720	COG2310	stress, protein
GII87_01725	COG2310	stress, protein
GII87_01730	COG0861	Integral membrane protein TerC family
GII87_01740	COG3853	Toxic anion resistance protein (TelA)
GII87_01745	COG0477	Major facilitator Superfamily
GII87_01750	COG2814	Major facilitator Superfamily
GII87_01755	COG0640	Transcriptional regulator
GII87_01760	COG4175	Glycine betaine
GII87_01760	COG0517	IMP dehydrogenase activity
GII87_01765	COG4176	ABC-type proline glycine betaine transport system permease component
GII87_01770	COG2113	Glycine betaine
GII87_01775	COG1473	amidohydrolase
GII87_01780	COG1288	antiporter activity
GII87_01790	COG0366	Alpha amylase catalytic
GII87_01795	COG0039	L-malate dehydrogenase activity
GII87_01800	COG1620	l-lactate permease
GII87_01805	COG2814	Major facilitator Superfamily
GII87_01810	COG1846	Transcriptional regulator
GII87_01815	COG1280	lysine exporter protein (LysE YggA)
GII87_01820	COG3403	YqcI/YcgG family
GII87_01825	COG1113	amino acid transport
GII87_01830	COG3665	Urea carboxylase-associated protein
GII87_01835	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII87_01840	COG1660	Displays ATPase and GTPase activities
GII87_01845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII87_01850	COG2226	methyltransferase
GII87_01855	COG0583	DNA-binding transcription factor activity
GII87_01860	COG3458	cephalosporin-C deacetylase activity
GII87_01865	COG3541	Predicted nucleotidyltransferase
GII87_01870	COG0506	proline dehydrogenase activity
GII87_01875	COG1012	belongs to the aldehyde dehydrogenase family
GII87_01880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII87_01885	COG2508	Transcriptional regulator
GII87_01890	COG3689	TIGRFAM TIGR03943 family protein
GII87_01895	COG0701	Predicted permease
GII87_01900	COG2267	carboxylic ester hydrolase activity
GII87_01905	COG0492	ferredoxin-NADP+ reductase activity
GII87_01910	COG1587	Uroporphyrinogen-III synthase
GII87_01910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII87_01915	COG2146	nitrite reductase [NAD(P)H] activity
GII87_01920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII87_01925	COG0243	molybdopterin cofactor binding
GII87_01930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII87_01935	COG2223	nitrite transmembrane transporter activity
GII87_01940	COG1469	GTP cyclohydrolase I activity
GII87_01945	COG1376	ErfK ybiS ycfS ynhG family protein
GII87_01955	COG0523	cobalamin synthesis protein
GII87_01960	COG0765	amino acid transport
GII87_01965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII87_01975	COG1714	RDD family
GII87_01985	COG2723	6-phospho-beta-galactosidase activity
GII87_01995	COG3209	COG3209 Rhs family protein
GII87_02000	COG3290	protein histidine kinase activity
GII87_02000	COG0840	transmembrane signaling receptor activity
GII87_02005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII87_02010	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII87_02015	COG1733	regulation of RNA biosynthetic process
GII87_02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_02035	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII87_02040	COG2814	Major facilitator Superfamily
GII87_02050	COG0697	spore germination
GII87_02055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII87_02065	COG2364	Membrane
GII87_02070	COG1126	abc transporter atp-binding protein
GII87_02075	COG0765	amino acid transport
GII87_02080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII87_02085	COG0583	DNA-binding transcription factor activity
GII87_02090	COG0163	prenyltransferase activity
GII87_02095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII87_02110	COG0596	Alpha beta hydrolase
GII87_02115	COG3104	oligopeptide transport
GII87_02120	COG5434	Belongs to the glycosyl hydrolase 28 family
GII87_02130	COG0697	spore germination
GII87_02140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII87_02145	COG1136	(ABC) transporter
GII87_02150	COG0577	efflux transmembrane transporter activity
GII87_02155	COG0745	RESPONSE REGULATOR receiver
GII87_02160	COG5002	protein histidine kinase activity
GII87_02160	COG3850	Histidine kinase
GII87_02165	COG0457	Tetratricopeptide repeat
GII87_02185	COG0527	aspartate kinase activity
GII87_02190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII87_02195	COG4605	iron ion homeostasis
GII87_02200	COG4604	ABC transporter, ATP-binding protein
GII87_02205	COG4607	ABC-type enterochelin transport system periplasmic component
GII87_02210	COG2814	Major facilitator Superfamily
GII87_02215	COG1309	transcriptional regulator
GII87_02220	COG0778	Nitroreductase
GII87_02225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII87_02230	COG0640	Transcriptional regulator
GII87_02235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII87_02240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII87_02245	COG1012	belongs to the aldehyde dehydrogenase family
GII87_02250	COG4975	Glucose uptake
GII87_02255	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_02260	COG4549	nuclear export factor GLE1
GII87_02265	COG2372	response to copper ion
GII87_02265	COG1276	copper resistance
GII87_02270	COG1349	DNA-binding transcription factor activity
GII87_02280	COG2213	PTS system mannitol-specific
GII87_02285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII87_02290	COG0246	Mannitol dehydrogenase
GII87_02295	COG0473	3-isopropylmalate dehydrogenase activity
GII87_02300	COG0681	Belongs to the peptidase S26 family
GII87_02305	COG0412	Dienelactone hydrolase
GII87_02310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII87_02320	COG0561	phosphatase activity
GII87_02325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII87_02330	COG1914	H( )-stimulated, divalent metal cation uptake system
GII87_02335	COG4336	lyase activity
GII87_02340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII87_02345	COG1984	allophanate hydrolase subunit 2
GII87_02350	COG1414	Transcriptional regulator
GII87_02355	COG2755	lipolytic protein G-D-S-L family
GII87_02365	COG2329	Antibiotic biosynthesis monooxygenase
GII87_02370	COG0768	penicillin binding
GII87_02375	COG4989	oxidoreductase activity
GII87_02380	COG3711	transcriptional antiterminator
GII87_02385	COG0318	PFAM AMP-dependent synthetase and ligase
GII87_02390	COG2226	methyltransferase
GII87_02395	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_02400	COG1917	Cupin 2, conserved barrel domain protein
GII87_02405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII87_02410	COG3871	stress protein (general stress protein 26)
GII87_02420	COG2814	Major facilitator Superfamily
GII87_02425	COG1522	sequence-specific DNA binding
GII87_02430	COG0551	DNA topoisomerase type I activity
GII87_02430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII87_02435	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII87_02440	COG3706	GGDEF domain
GII87_02445	COG5298	Protein conserved in bacteria
GII87_02450	COG1215	transferase activity, transferring glycosyl groups
GII87_02460	COG0531	amino acid
GII87_02465	COG0494	nUDIX hydrolase
GII87_02470	COG0028	Belongs to the TPP enzyme family
GII87_02485	COG1914	H( )-stimulated, divalent metal cation uptake system
GII87_02490	COG2261	transglycosylase associated protein
GII87_02495	COG4876	unkown
GII87_02500	COG2217	Heavy metal translocating P-type atpase
GII87_02505	COG3729	General stress protein
GII87_02510	COG0662	Cupin 2, conserved barrel domain protein
GII87_02515	COG2329	Antibiotic biosynthesis monooxygenase
GII87_02520	COG3546	catalase activity
GII87_02525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII87_02530	COG3290	protein histidine kinase activity
GII87_02535	COG4565	transcriptional regulatory protein
GII87_02540	COG1301	dicarboxylic acid transport
GII87_02545	COG0628	permease
GII87_02550	COG1131	(ABC) transporter
GII87_02555	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII87_02565	COG1960	acyl-CoA dehydrogenase activity
GII87_02580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII87_02585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_02590	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII87_02595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII87_02600	COG0513	Belongs to the DEAD box helicase family
GII87_02605	COG3402	PFAM membrane-flanked domain
GII87_02610	COG3428	Bacterial PH domain
GII87_02615	COG0705	Rhomboid family
GII87_02620	COG0736	holo-[acyl-carrier-protein] synthase activity
GII87_02625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII87_02630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII87_02635	COG0864	Transcriptional regulator
GII87_02640	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII87_02645	COG1366	Belongs to the anti-sigma-factor antagonist family
GII87_02650	COG1366	Belongs to the anti-sigma-factor antagonist family
GII87_02655	COG2172	sigma factor antagonist activity
GII87_02660	COG2208	phosphoserine phosphatase activity
GII87_02665	COG1366	Belongs to the anti-sigma-factor antagonist family
GII87_02670	COG2172	sigma factor antagonist activity
GII87_02675	COG1191	sigma factor activity
GII87_02680	COG2208	phosphoserine phosphatase activity
GII87_02695	COG1673	EVE domain
GII87_02700	COG1846	Transcriptional regulator
GII87_02705	COG2183	response to ionizing radiation
GII87_02715	COG3091	SprT-like family
GII87_02755	COG0582	viral genome integration into host DNA
GII87_02760	COG2856	Zn peptidase
GII87_02765	COG1396	sequence-specific DNA binding
GII87_02795	COG1674	ftsk spoiiie
GII87_02800	COG2946	Replication initiation factor
GII87_02835	COG0433	COG0433 Predicted ATPase
GII87_02845	COG5644	endopeptidase inhibitor activity
GII87_02850	COG0791	NLP P60 protein
GII87_02850	COG0741	lytic transglycosylase activity
GII87_02870	COG0457	Tetratricopeptide repeat
GII87_02885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII87_02890	COG1522	sequence-specific DNA binding
GII87_02895	COG1522	sequence-specific DNA binding
GII87_02900	COG1335	isochorismatase
GII87_02905	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII87_02910	COG2814	Major facilitator Superfamily
GII87_02930	COG0693	protein deglycase activity
GII87_02935	COG1278	Cold shock
GII87_02940	COG1329	Transcriptional regulator
GII87_02950	COG2207	Transcriptional regulator
GII87_02950	COG1917	Cupin 2, conserved barrel domain protein
GII87_02955	COG0697	spore germination
GII87_02960	COG2207	Transcriptional regulator
GII87_02960	COG3708	Transcriptional regulator
GII87_02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII87_02970	COG0477	Major facilitator Superfamily
GII87_02980	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII87_02990	COG0697	spore germination
GII87_02995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII87_03000	COG2030	dehydratase
GII87_03005	COG3545	Serine hydrolase
GII87_03010	COG1733	regulation of RNA biosynthetic process
GII87_03015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII87_03020	COG1733	regulation of RNA biosynthetic process
GII87_03025	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII87_03030	COG2814	Major facilitator Superfamily
GII87_03035	COG1309	transcriptional regulator
GII87_03045	COG0640	Transcriptional regulator
GII87_03050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII87_03060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII87_03065	COG0697	spore germination
GII87_03070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII87_03075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII87_03080	COG0640	Transcriptional regulator
GII87_03085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII87_03100	COG4585	Histidine kinase
GII87_03105	COG2197	response regulator
GII87_03110	COG2409	Drug exporters of the RND superfamily
GII87_03115	COG0596	Alpha beta hydrolase
GII87_03120	COG1811	Na channel or pump
GII87_03125	COG4978	Transcriptional regulator
GII87_03125	COG0789	Transcriptional regulator
GII87_03130	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII87_03135	COG0778	Nitroreductase
GII87_03140	COG0346	lactoylglutathione lyase activity
GII87_03145	COG2259	Doxx family
GII87_03150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_03165	COG2323	membrane
GII87_03170	COG2323	membrane
GII87_03175	COG0071	Belongs to the small heat shock protein (HSP20) family
GII87_03190	COG1309	transcriptional regulator
GII87_03200	COG0456	acetyltransferase
GII87_03210	COG1113	amino acid transport
GII87_03215	COG2318	DinB family
GII87_03220	COG1846	Transcriptional regulator
GII87_03225	COG1033	growth of symbiont in host cell
GII87_03225	COG2409	Drug exporters of the RND superfamily
GII87_03230	COG0778	Nitroreductase
GII87_03235	COG1846	Transcriptional regulator
GII87_03240	COG2814	Major facilitator Superfamily
GII87_03245	COG0730	response to heat
GII87_03250	COG1802	Transcriptional regulator
GII87_03255	COG1388	LysM domain
GII87_03255	COG3858	chitin binding
GII87_03260	COG1819	glycosyl
GII87_03270	COG1785	Belongs to the alkaline phosphatase family
GII87_03275	COG5646	InterPro IPR014922
GII87_03285	COG0454	-acetyltransferase
GII87_03290	COG1078	dGTPase activity
GII87_03295	COG1388	LysM domain
GII87_03300	COG2814	Major facilitator Superfamily
GII87_03305	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII87_03310	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII87_03315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII87_03320	COG2723	6-phospho-beta-galactosidase activity
GII87_03325	COG2188	Transcriptional regulator
GII87_03330	COG1940	carbohydrate kinase activity
GII87_03335	COG1482	cell wall glycoprotein biosynthetic process
GII87_03340	COG4124	Belongs to the glycosyl hydrolase 26 family
GII87_03385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII87_03390	COG0802	atpase or kinase
GII87_03395	COG1214	PFAM Peptidase M22, glycoprotease
GII87_03400	COG0456	acetyltransferase
GII87_03405	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII87_03410	COG0488	(ABC) transporter
GII87_03415	COG0315	cyclic pyranopterin monophosphate synthase activity
GII87_03420	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII87_03425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII87_03430	COG0805	protein transport
GII87_03440	COG1266	CAAX protease self-immunity
GII87_03445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GII87_03450	COG0459	protein refolding
GII87_03460	COG3378	Phage plasmid primase P4 family
GII87_03475	COG0270	DNA (cytosine-5-)-methyltransferase activity
GII87_03480	COG0270	DNA (cytosine-5-)-methyltransferase activity
GII87_03500	COG1401	restriction endodeoxyribonuclease activity
GII87_03520	COG1073	alpha beta
GII87_03525	COG0457	Tetratricopeptide repeat
GII87_03530	COG1063	alcohol dehydrogenase
GII87_03535	COG2211	Major facilitator Superfamily
GII87_03540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII87_03545	COG1842	Phage shock protein A
GII87_03550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII87_03555	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII87_03560	COG4260	virion core protein, lumpy skin disease virus
GII87_03570	COG2814	Major facilitator Superfamily
GII87_03575	COG1063	alcohol dehydrogenase
GII87_03580	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII87_03585	COG0823	Involved in the tonB-independent uptake of proteins
GII87_03600	COG2267	carboxylic ester hydrolase activity
GII87_03610	COG2132	Multicopper oxidase
GII87_03615	COG1113	amino acid transport
GII87_03625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII87_03630	COG0714	Associated with various cellular activities
GII87_03635	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII87_03640	COG1305	Transglutaminase-like
GII87_03645	COG0519	Catalyzes the synthesis of GMP from XMP
GII87_03645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII87_03650	COG2252	PERMEase
GII87_03655	COG3064	Membrane
GII87_03665	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII87_03675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII87_03680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII87_03685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII87_03690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII87_03695	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII87_03700	COG0047	phosphoribosylformylglycinamidine synthase activity
GII87_03705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII87_03710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII87_03715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII87_03720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII87_03725	COG0138	bifunctional purine biosynthesis protein purh
GII87_03730	COG0151	Belongs to the GarS family
GII87_03735	COG1522	sequence-specific DNA binding
GII87_03740	COG0531	amino acid
GII87_03750	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII87_03755	COG1470	cell adhesion involved in biofilm formation
GII87_03760	COG4496	protein, YerC YecD
GII87_03765	COG0069	glutamate synthase activity
GII87_03770	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII87_03775	COG0210	DNA helicase
GII87_03780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII87_03785	COG4851	CamS sex pheromone cAM373 precursor
GII87_03790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII87_03795	COG1285	pathogenesis
GII87_03800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII87_03805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII87_03810	COG0154	amidase activity
GII87_03815	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII87_03820	COG1309	transcriptional regulator
GII87_03825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII87_03830	COG1597	lipid kinase activity
GII87_03835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII87_03840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII87_03845	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII87_03850	COG1002	Type II restriction enzyme, methylase subunits
GII87_03855	COG1061	Type III restriction enzyme res subunit
GII87_03860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII87_03880	COG5444	nuclease activity
GII87_03885	COG3391	amine dehydrogenase activity
GII87_03890	COG0457	Tetratricopeptide repeat
GII87_03900	COG0217	transcriptional regulatory protein
GII87_03910	COG1309	transcriptional regulator
GII87_03915	COG3631	Ketosteroid isomerase-related protein
GII87_03920	COG0702	epimerase
GII87_03935	COG3546	catalase activity
GII87_03940	COG0454	-acetyltransferase
GII87_03950	COG5578	integral membrane protein
GII87_03955	COG2972	Histidine kinase
GII87_03960	COG4753	response regulator
GII87_03960	COG2207	Transcriptional regulator
GII87_03965	COG1653	transport
GII87_03970	COG1175	transmembrane transport
GII87_03975	COG0395	ABC-type sugar transport system, permease component
GII87_03980	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII87_03985	COG2207	Transcriptional regulator
GII87_03990	COG2755	lipolytic protein G-D-S-L family
GII87_04000	COG5578	integral membrane protein
GII87_04005	COG3401	FG-GAP repeat protein
GII87_04010	COG3401	FG-GAP repeat protein
GII87_04015	COG2755	lipolytic protein G-D-S-L family
GII87_04020	COG1874	Beta-galactosidase
GII87_04030	COG1653	transport
GII87_04035	COG4209	transmembrane transport
GII87_04040	COG0395	ABC-type sugar transport system, permease component
GII87_04045	COG1486	melibiose metabolic process
GII87_04050	COG2323	membrane
GII87_04055	COG2329	Antibiotic biosynthesis monooxygenase
GII87_04060	COG0346	lactoylglutathione lyase activity
GII87_04075	COG5583	Uncharacterized small protein (DUF2292)
GII87_04080	COG0670	Belongs to the BI1 family
GII87_04085	COG0697	spore germination
GII87_04090	COG1846	Transcriptional regulator
GII87_04095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII87_04105	COG2124	cytochrome p450
GII87_04105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII87_04110	COG1368	sulfuric ester hydrolase activity
GII87_04115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII87_04120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII87_04125	COG1442	glycosyl transferase family 8
GII87_04130	COG1216	Glycosyl transferase, family 2
GII87_04135	COG1442	glycosyl transferase family 8
GII87_04140	COG2223	nitrite transmembrane transporter activity
GII87_04145	COG1011	Hydrolase
GII87_04150	COG0531	amino acid
GII87_04155	COG1012	belongs to the aldehyde dehydrogenase family
GII87_04160	COG0840	transmembrane signaling receptor activity
GII87_04165	COG0488	(ABC) transporter
GII87_04175	COG0789	Transcriptional regulator
GII87_04180	COG2814	Major facilitator Superfamily
GII87_04190	COG0488	(ABC) transporter
GII87_04195	COG0513	Belongs to the DEAD box helicase family
GII87_04200	COG0456	acetyltransferase
GII87_04205	COG2130	NADP-dependent
GII87_04210	COG2211	Major facilitator Superfamily
GII87_04215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GII87_04220	COG1120	ATPase activity
GII87_04225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII87_04230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII87_04235	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII87_04250	COG3866	Pectate lyase
GII87_04255	COG0471	metal ion transport
GII87_04260	COG3290	protein histidine kinase activity
GII87_04265	COG4565	transcriptional regulatory protein
GII87_04270	COG3181	Tripartite tricarboxylate transporter family receptor
GII87_04275	COG2851	Citrate transporter
GII87_04280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII87_04285	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII87_04290	COG1254	Belongs to the acylphosphatase family
GII87_04295	COG2258	MOSC domain
GII87_04315	COG0024	Methionine aminopeptidase
GII87_04320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_04320	COG1263	PTS System
GII87_04325	COG1368	sulfuric ester hydrolase activity
GII87_04340	COG1115	amino acid carrier protein
GII87_04345	COG0531	amino acid
GII87_04360	COG0697	spore germination
GII87_04365	COG1263	PTS System
GII87_04365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_04370	COG0366	Alpha amylase catalytic
GII87_04375	COG2188	Transcriptional regulator
GII87_04380	COG0778	Nitroreductase
GII87_04385	COG0737	Belongs to the 5'-nucleotidase family
GII87_04390	COG0693	protein deglycase activity
GII87_04395	COG2814	Major facilitator Superfamily
GII87_04400	COG4840	Belongs to the UPF0435 family
GII87_04405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII87_04410	COG4980	gas vesicle protein
GII87_04415	COG1295	ribonuclease BN
GII87_04420	COG0477	Major facilitator Superfamily
GII87_04430	COG0387	Pfam Sodium calcium exchanger
GII87_04440	COG0668	transmembrane transport
GII87_04445	COG0535	radical SAM domain protein
GII87_04455	COG0726	polysaccharide deacetylase
GII87_04460	COG2084	Dehydrogenase
GII87_04465	COG0598	Magnesium transport protein CorA
GII87_04470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII87_04475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII87_04485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII87_04490	COG4637	Psort location Cytoplasmic, score
GII87_04500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII87_04505	COG0022	dehydrogenase e1 component
GII87_04510	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII87_04515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII87_04520	COG3284	Transcriptional regulator
GII87_04530	COG1742	UPF0060 membrane protein
GII87_04555	COG4842	Belongs to the WXG100 family
GII87_04560	COG1486	melibiose metabolic process
GII87_04565	COG1737	Transcriptional regulator
GII87_04570	COG1263	PTS System
GII87_04570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_04575	COG1132	(ABC) transporter
GII87_04580	COG1132	(ABC) transporter
GII87_04585	COG2259	Doxx family
GII87_04590	COG2514	catechol 2,3-dioxygenase activity
GII87_04595	COG4977	sequence-specific DNA binding
GII87_04595	COG1917	Cupin 2, conserved barrel domain protein
GII87_04600	COG2814	Major facilitator Superfamily
GII87_04605	COG1082	Xylose isomerase domain protein TIM barrel
GII87_04610	COG0673	inositol 2-dehydrogenase activity
GII87_04615	COG4585	Histidine kinase
GII87_04620	COG2197	response regulator
GII87_04625	COG1131	(ABC) transporter
GII87_04630	COG1511	domain protein
GII87_04630	COG0842	Transport permease protein
GII87_04635	COG0842	Transport permease protein
GII87_04640	COG1695	Transcriptional regulator
GII87_04645	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII87_04650	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII87_04655	COG1309	transcriptional regulator
GII87_04660	COG2814	Major facilitator Superfamily
GII87_04665	COG2318	DinB family
GII87_04670	COG2814	Major facilitator Superfamily
GII87_04675	COG1846	Transcriptional regulator
GII87_04680	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII87_04680	COG0392	lysyltransferase activity
GII87_04685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII87_04690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII87_04695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII87_04700	COG0384	phenazine biosynthesis protein PhzF
GII87_04705	COG0778	Nitroreductase
GII87_04720	COG1090	epimerase
GII87_04725	COG2137	regulation of response to DNA damage stimulus
GII87_04735	COG2814	Major facilitator Superfamily
GII87_04750	COG3103	Sh3 type 3 domain protein
GII87_04755	COG5658	integral membrane protein
GII87_04760	COG0596	Alpha beta hydrolase
GII87_04765	COG0463	Glycosyl transferase, family 2
GII87_04770	COG4485	Bacterial membrane protein, YfhO
GII87_04775	COG1988	membrane-bound metal-dependent
GII87_04780	COG1194	a g-specific adenine glycosylase
GII87_04790	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_04805	COG3557	Belongs to the UPF0374 family
GII87_04810	COG1132	(ABC) transporter
GII87_04815	COG4129	membrane
GII87_04820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII87_04825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII87_04830	COG0735	belongs to the Fur family
GII87_04940	COG4326	sporulation control protein
GII87_04950	COG5577	PFAM Coat F domain
GII87_04955	COG3340	Belongs to the peptidase S51 family
GII87_04960	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII87_04965	COG0277	FAD linked oxidase domain protein
GII87_04975	COG0753	catalase activity
GII87_04980	COG1116	anion transmembrane transporter activity
GII87_04985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII87_04990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII87_04995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII87_05005	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII87_05015	COG1476	TRANSCRIPTIONal
GII87_05025	COG3382	B3 4 domain protein
GII87_05030	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII87_05040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII87_05045	COG0789	Transcriptional regulator
GII87_05050	COG1664	Polymer-forming cytoskeletal
GII87_05055	COG1664	Polymer-forming cytoskeletal
GII87_05060	COG2766	serine protein kinase
GII87_05065	COG2718	Belongs to the UPF0229 family
GII87_05070	COG1846	Transcriptional regulator
GII87_05075	COG1566	PFAM secretion protein HlyD family protein
GII87_05080	COG2814	Major facilitator Superfamily
GII87_05085	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII87_05105	COG1725	Transcriptional regulator
GII87_05110	COG1131	(ABC) transporter
GII87_05115	COG1131	(ABC) transporter
GII87_05120	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII87_05125	COG1278	Cold shock
GII87_05130	COG1464	Belongs to the NlpA lipoprotein family
GII87_05135	COG3706	GGDEF domain
GII87_05140	COG1823	symporter activity
GII87_05160	COG5577	PFAM Coat F domain
GII87_05165	COG0737	Belongs to the 5'-nucleotidase family
GII87_05165	COG4085	toxin activity
GII87_05165	COG1525	nuclease
GII87_05170	COG3764	Sortase (surface protein transpeptidase)
GII87_05175	COG0564	pseudouridine synthase activity
GII87_05185	COG0517	IMP dehydrogenase activity
GII87_05190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII87_05195	COG3153	acetyltransferase
GII87_05195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII87_05200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII87_05205	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII87_05210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII87_05215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII87_05220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII87_05225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII87_05230	COG4585	Histidine kinase
GII87_05230	COG2203	Gaf domain
GII87_05235	COG2197	response regulator
GII87_05240	COG0431	NADPH-dependent FMN reductase
GII87_05255	COG0791	NLP P60 protein
GII87_05255	COG1388	LysM domain
GII87_05260	COG1959	2 iron, 2 sulfur cluster binding
GII87_05265	COG0668	transmembrane transport
GII87_05270	COG2719	SpoVR family
GII87_05275	COG1785	Belongs to the alkaline phosphatase family
GII87_05280	COG1388	LysM domain
GII87_05280	COG0791	NLP P60 protein
GII87_05285	COG0583	DNA-binding transcription factor activity
GII87_05290	COG0372	Belongs to the citrate synthase family
GII87_05295	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_05300	COG0531	amino acid
GII87_05305	COG0733	neurotransmitter:sodium symporter activity
GII87_05310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII87_05315	COG0456	acetyltransferase
GII87_05330	COG1595	DNA-templated transcription, initiation
GII87_05335	COG0667	Aldo Keto reductase
GII87_05340	COG0204	Acyl-transferase
GII87_05345	COG1253	flavin adenine dinucleotide binding
GII87_05350	COG0789	Transcriptional regulator
GII87_05355	COG0436	Aminotransferase
GII87_05360	COG1253	flavin adenine dinucleotide binding
GII87_05365	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII87_05370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII87_05375	COG0584	glycerophosphoryl diester phosphodiesterase
GII87_05385	COG0668	transmembrane transport
GII87_05390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII87_05395	COG0726	polysaccharide deacetylase
GII87_05400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII87_05405	COG1757	Na H antiporter
GII87_05410	COG0589	response to stress
GII87_05420	COG1132	(ABC) transporter
GII87_05425	COG1132	(ABC) transporter
GII87_05430	COG0702	epimerase
GII87_05450	COG0189	ligase activity
GII87_05455	COG0189	ligase activity
GII87_05460	COG4399	Belongs to the UPF0754 family
GII87_05465	COG3679	Belongs to the UPF0342 family
GII87_05470	COG4335	DNA alkylation repair
GII87_05475	COG0561	phosphatase activity
GII87_05480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII87_05485	COG0475	glutathione-regulated potassium exporter activity
GII87_05490	COG0490	domain, Protein
GII87_05500	COG1024	Enoyl-CoA hydratase
GII87_05510	COG4152	abc transporter atp-binding protein
GII87_05515	COG1668	transmembrane transport
GII87_05520	COG0420	3'-5' exonuclease activity
GII87_05525	COG4717	serine-type aminopeptidase activity
GII87_05530	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII87_05540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII87_05570	COG1846	Transcriptional regulator
GII87_05575	COG4980	gas vesicle protein
GII87_05590	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII87_05595	COG0537	adenosine 5'-monophosphoramidase activity
GII87_05600	COG1131	(ABC) transporter
GII87_05605	COG4473	ABC transporter
GII87_05615	COG1473	amidohydrolase
GII87_05620	COG3069	C4-dicarboxylate transmembrane transporter activity
GII87_05630	COG2329	Antibiotic biosynthesis monooxygenase
GII87_05635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII87_05640	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII87_05655	COG1309	transcriptional regulator
GII87_05660	COG1511	domain protein
GII87_05665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII87_05670	COG4377	Putative membrane peptidase family (DUF2324)
GII87_05680	COG1363	Peptidase, m42
GII87_05685	COG4405	Protein conserved in bacteria
GII87_05690	COG1301	dicarboxylic acid transport
GII87_05700	COG1234	tRNA 3'-trailer cleavage
GII87_05705	COG0095	Lipoate-protein ligase
GII87_05710	COG0702	epimerase
GII87_05715	COG0318	PFAM AMP-dependent synthetase and ligase
GII87_05725	COG0501	Belongs to the peptidase M48B family
GII87_05730	COG1404	Belongs to the peptidase S8 family
GII87_05735	COG0456	acetyltransferase
GII87_05740	COG0604	alcohol dehydrogenase
GII87_05745	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII87_05750	COG0406	alpha-ribazole phosphatase activity
GII87_05755	COG0183	Belongs to the thiolase family
GII87_05760	COG0318	PFAM AMP-dependent synthetase and ligase
GII87_05765	COG1268	BioY protein
GII87_05770	COG0840	transmembrane signaling receptor activity
GII87_05775	COG0723	plastoquinol--plastocyanin reductase activity
GII87_05775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII87_05780	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_05790	COG4903	ComK protein
GII87_05795	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_05805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII87_05820	COG0398	Pfam SNARE associated Golgi protein
GII87_05825	COG0681	Belongs to the peptidase S26 family
GII87_05830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII87_05835	COG1846	Transcriptional regulator
GII87_05840	COG0738	Major facilitator superfamily
GII87_05845	COG0673	inositol 2-dehydrogenase activity
GII87_05850	COG0561	phosphatase activity
GII87_05855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII87_05860	COG1609	Transcriptional regulator
GII87_05865	COG3180	Ammonia monooxygenase
GII87_05870	COG0477	Major facilitator Superfamily
GII87_05870	COG2814	Major facilitator Superfamily
GII87_05875	COG4533	DNA binding
GII87_05885	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII87_05890	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII87_05895	COG1074	ATP-dependent DNA helicase activity
GII87_05900	COG0420	3'-5' exonuclease activity
GII87_05905	COG0419	ATPase involved in DNA repair
GII87_05910	COG1403	HNH endonuclease
GII87_05950	COG5337	Spore coat protein CotH
GII87_05955	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII87_05965	COG1404	Belongs to the peptidase S8 family
GII87_05975	COG0367	asparagine synthase
GII87_05980	COG2318	DinB family
GII87_05985	COG1562	ergosterol biosynthetic process
GII87_05990	COG0534	Mate efflux family protein
GII87_05995	COG2207	Transcriptional regulator
GII87_05995	COG1917	Cupin 2, conserved barrel domain protein
GII87_06000	COG1609	Transcriptional regulator
GII87_06005	COG0673	inositol 2-dehydrogenase activity
GII87_06010	COG2318	DinB family
GII87_06015	COG1279	arginine transmembrane transporter activity
GII87_06020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII87_06025	COG1357	PFAM Pentapeptide repeats (8 copies)
GII87_06030	COG2267	carboxylic ester hydrolase activity
GII87_06035	COG0529	Catalyzes the synthesis of activated sulfate
GII87_06040	COG2046	Belongs to the sulfate adenylyltransferase family
GII87_06045	COG0175	sulfate reduction
GII87_06050	COG2045	Belongs to the ComB family
GII87_06055	COG1809	phosphosulfolactate synthase activity
GII87_06060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII87_06065	COG4948	Mandelate Racemase Muconate Lactonizing
GII87_06070	COG2814	Major facilitator Superfamily
GII87_06075	COG0454	-acetyltransferase
GII87_06080	COG2153	protein acetylation
GII87_06085	COG0646	methionine synthase
GII87_06085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII87_06090	COG1666	GTP binding
GII87_06095	COG2996	Protein conserved in bacteria
GII87_06115	COG1695	Transcriptional regulator
GII87_06130	COG3227	Zinc metalloprotease (Elastase)
GII87_06135	COG1307	EDD domain protein, DegV family
GII87_06140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII87_06155	COG0561	phosphatase activity
GII87_06160	COG1073	alpha beta
GII87_06165	COG2151	metal-sulfur cluster biosynthetic enzyme
GII87_06175	COG0277	FAD linked oxidase domain protein
GII87_06180	COG2271	Major facilitator Superfamily
GII87_06185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII87_06200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII87_06205	COG0505	Belongs to the CarA family
GII87_06210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII87_06215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII87_06230	COG2267	carboxylic ester hydrolase activity
GII87_06240	COG1744	ABC transporter substrate-binding protein PnrA-like
GII87_06255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII87_06260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII87_06265	COG5504	Zn-dependent protease
GII87_06270	COG0444	Belongs to the ABC transporter superfamily
GII87_06275	COG4608	Belongs to the ABC transporter superfamily
GII87_06285	COG0601	transmembrane transport
GII87_06290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII87_06300	COG0180	Tryptophanyl-tRNA synthetase
GII87_06305	COG4166	transmembrane transport
GII87_06310	COG0601	transmembrane transport
GII87_06315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII87_06320	COG0444	Belongs to the ABC transporter superfamily
GII87_06325	COG4608	Belongs to the ABC transporter superfamily
GII87_06330	COG2814	Major facilitator Superfamily
GII87_06335	COG0456	acetyltransferase
GII87_06340	COG1393	Belongs to the ArsC family
GII87_06345	COG0861	Integral membrane protein TerC family
GII87_06355	COG4862	establishment of competence for transformation
GII87_06365	COG4469	Competence protein
GII87_06370	COG1164	Oligoendopeptidase f
GII87_06385	COG2346	COG2346, Truncated hemoglobins
GII87_06390	COG0741	lytic transglycosylase activity
GII87_06395	COG4116	CYTH
GII87_06405	COG2357	RelA SpoT domain protein
GII87_06410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII87_06415	COG0564	pseudouridine synthase activity
GII87_06420	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII87_06425	COG0569	domain protein
GII87_06425	COG0475	glutathione-regulated potassium exporter activity
GII87_06430	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII87_06435	COG0352	thiamine-phosphate diphosphorylase activity
GII87_06440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII87_06445	COG2104	thiamine diphosphate biosynthetic process
GII87_06450	COG2022	thiamine diphosphate biosynthetic process
GII87_06455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII87_06460	COG0351	phosphomethylpyrimidine kinase
GII87_06465	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII87_06520	COG0210	DNA helicase
GII87_06530	COG2153	protein acetylation
GII87_06535	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII87_06540	COG2382	esterase
GII87_06545	COG0626	cystathionine gamma-synthase activity
GII87_06550	COG0626	cystathionine gamma-synthase activity
GII87_06555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII87_06560	COG5505	Protein of unknown function (DUF819)
GII87_06590	COG3677	Transposase
GII87_06605	COG5484	DNA packaging
GII87_06610	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII87_06615	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_06625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII87_06625	COG3711	transcriptional antiterminator
GII87_06630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII87_06630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII87_06630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII87_06635	COG1482	cell wall glycoprotein biosynthetic process
GII87_06645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII87_06655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII87_06670	COG0109	protoheme IX farnesyltransferase activity
GII87_06680	COG0726	polysaccharide deacetylase
GII87_06695	COG5504	Zn-dependent protease
GII87_06700	COG2205	protein histidine kinase activity
GII87_06710	COG3383	formate dehydrogenase (NAD+) activity
GII87_06715	COG2427	Protein of unknown function (DUF1641)
GII87_06725	COG1051	belongs to the nudix hydrolase family
GII87_06735	COG2124	cytochrome p450
GII87_06740	COG1819	glycosyl
GII87_06750	COG1587	Uroporphyrinogen-III synthase
GII87_06755	COG0390	transport system, permease component
GII87_06760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII87_06765	COG0697	spore germination
GII87_06770	COG4297	protein containing double-stranded beta helix domain
GII87_06780	COG1252	NADH dehydrogenase
GII87_06785	COG1904	glucuronate isomerase
GII87_06790	COG2211	Major facilitator Superfamily
GII87_06795	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII87_06800	COG1063	alcohol dehydrogenase
GII87_06805	COG1312	Catalyzes the dehydration of D-mannonate
GII87_06810	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_06815	COG2271	Major facilitator Superfamily
GII87_06820	COG1609	Transcriptional regulator
GII87_06825	COG0246	Mannitol dehydrogenase
GII87_06830	COG2721	sulfolactate sulfo-lyase activity
GII87_06835	COG0730	response to heat
GII87_06840	COG2318	DinB family
GII87_06845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII87_06850	COG0457	Tetratricopeptide repeat
GII87_06860	COG2350	Protein conserved in bacteria
GII87_06865	COG1388	LysM domain
GII87_06865	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII87_06865	COG3409	Peptidoglycan-binding domain 1 protein
GII87_06875	COG4195	phage-related replication protein
GII87_06880	COG3546	catalase activity
GII87_06885	COG2856	Zn peptidase
GII87_06890	COG1396	sequence-specific DNA binding
GII87_06900	COG1522	sequence-specific DNA binding
GII87_06905	COG1484	DNA-dependent DNA replication
GII87_06925	COG1595	DNA-templated transcription, initiation
GII87_06930	COG3728	DNA packaging
GII87_06930	COG5484	DNA packaging
GII87_06935	COG1783	phage Terminase large subunit
GII87_06940	COG5518	Phage portal protein
GII87_06945	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII87_06950	COG4653	Phage capsid family
GII87_07000	COG3953	SLT domain
GII87_07000	COG5412	phage tail tape measure protein
GII87_07005	COG1652	LysM domain
GII87_07010	COG4193	domain, Protein
GII87_07020	COG3628	GPW Gp25 family protein
GII87_07025	COG3299	homolog of phage Mu protein gp47
GII87_07030	COG3778	Protein conserved in bacteria
GII87_07070	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII87_07070	COG3409	Peptidoglycan-binding domain 1 protein
GII87_07090	COG0306	phosphate transporter
GII87_07095	COG1392	Phosphate transport regulator
GII87_07100	COG0531	amino acid
GII87_07105	COG0346	lactoylglutathione lyase activity
GII87_07115	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII87_07120	COG0463	Glycosyl transferase, family 2
GII87_07125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII87_07130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII87_07135	COG2362	D-Aminopeptidase
GII87_07140	COG0601	transmembrane transport
GII87_07145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII87_07150	COG0444	Belongs to the ABC transporter superfamily
GII87_07155	COG4166	transmembrane transport
GII87_07160	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII87_07165	COG4948	Mandelate Racemase Muconate Lactonizing
GII87_07170	COG0791	NLP P60 protein
GII87_07175	COG4608	Belongs to the ABC transporter superfamily
GII87_07180	COG2706	6-phosphogluconolactonase activity
GII87_07185	COG1834	amidinotransferase
GII87_07190	COG1607	acyl-coa hydrolase
GII87_07195	COG1017	nitric oxide dioxygenase activity
GII87_07195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII87_07205	COG2323	membrane
GII87_07210	COG2318	DinB family
GII87_07215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII87_07220	COG2076	Multidrug Resistance protein
GII87_07225	COG2076	Multidrug Resistance protein
GII87_07230	COG0788	formyltetrahydrofolate deformylase activity
GII87_07235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII87_07240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII87_07245	COG1764	response to oxidative stress
GII87_07250	COG1846	Transcriptional regulator
GII87_07255	COG1764	response to oxidative stress
GII87_07265	COG0590	tRNA wobble adenosine to inosine editing
GII87_07270	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII87_07275	COG1404	Belongs to the peptidase S8 family
GII87_07280	COG1366	Belongs to the anti-sigma-factor antagonist family
GII87_07285	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII87_07290	COG1122	ATPase activity
GII87_07295	COG4721	ABC-type cobalt transport system, permease component
GII87_07305	COG0745	RESPONSE REGULATOR receiver
GII87_07310	COG3850	Histidine kinase
GII87_07310	COG5002	protein histidine kinase activity
GII87_07315	COG3212	peptidase
GII87_07320	COG3212	peptidase
GII87_07330	COG2239	Acts as a magnesium transporter
GII87_07335	COG0789	Transcriptional regulator
GII87_07350	COG1846	Transcriptional regulator
GII87_07355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII87_07360	COG0726	polysaccharide deacetylase
GII87_07365	COG1408	metallophosphoesterase
GII87_07375	COG0463	Glycosyl transferase, family 2
GII87_07380	COG3285	dna ligase
GII87_07380	COG1793	dna ligase
GII87_07385	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII87_07390	COG5001	Diguanylate cyclase
GII87_07390	COG3300	MHYT domain
GII87_07395	COG0586	Pfam SNARE associated Golgi protein
GII87_07400	COG0861	Integral membrane protein TerC family
GII87_07405	COG1191	sigma factor activity
GII87_07425	COG0501	Belongs to the peptidase M48B family
GII87_07430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII87_07445	COG3594	Acyltransferase
GII87_07450	COG5002	protein histidine kinase activity
GII87_07455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII87_07465	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII87_07470	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII87_07475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII87_07480	COG0436	Aminotransferase
GII87_07485	COG1850	ribulose-bisphosphate carboxylase activity
GII87_07490	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII87_07495	COG0235	Class ii aldolase
GII87_07500	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII87_07505	COG3339	Conserved Protein
GII87_07520	COG3852	Histidine kinase
GII87_07525	COG1846	Transcriptional regulator
GII87_07530	COG1360	Flagellar Motor Protein
GII87_07535	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII87_07540	COG0542	response to heat
GII87_07545	COG3949	Membrane
GII87_07550	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII87_07555	COG0720	synthase
GII87_07560	COG0602	queuosine metabolic process
GII87_07565	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII87_07570	COG1733	regulation of RNA biosynthetic process
GII87_07575	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_07580	COG4641	Protein conserved in bacteria
GII87_07580	COG1388	LysM domain
GII87_07585	COG1388	LysM domain
GII87_07600	COG4873	Protein conserved in bacteria
GII87_07610	COG3773	Cell wall hydrolase
GII87_07615	COG2244	polysaccharide biosynthetic process
GII87_07620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_07625	COG2217	Heavy metal translocating P-type atpase
GII87_07635	COG0006	proline dipeptidase activity
GII87_07640	COG1609	Transcriptional regulator
GII87_07645	COG3711	transcriptional antiterminator
GII87_07650	COG1263	PTS System
GII87_07650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_07650	COG2190	(PTS) system
GII87_07655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII87_07660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII87_07670	COG1533	DNA photolyase activity
GII87_07675	COG0456	acetyltransferase
GII87_07680	COG0840	transmembrane signaling receptor activity
GII87_07685	COG2084	Dehydrogenase
GII87_07690	COG2340	Cysteine-rich secretory protein family
GII87_07695	COG0768	penicillin binding
GII87_07700	COG4191	Histidine kinase
GII87_07705	COG0436	Aminotransferase
GII87_07715	COG0835	chemotaxis
GII87_07715	COG0784	Response regulator, receiver
GII87_07725	COG2814	Major facilitator Superfamily
GII87_07730	COG1376	ErfK ybiS ycfS ynhG family protein
GII87_07735	COG1408	metallophosphoesterase
GII87_07740	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_07745	COG3409	Peptidoglycan-binding domain 1 protein
GII87_07750	COG3409	Peptidoglycan-binding domain 1 protein
GII87_07760	COG2200	EAL domain
GII87_07770	COG4703	Protein of unknown function (DUF1797)
GII87_07775	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII87_07785	COG0517	IMP dehydrogenase activity
GII87_07790	COG0583	DNA-binding transcription factor activity
GII87_07795	COG0716	FMN binding
GII87_07805	COG0716	FMN binding
GII87_07810	COG2171	N-acyltransferase activity
GII87_07815	COG1473	amidohydrolase
GII87_07825	COG0668	transmembrane transport
GII87_07830	COG0450	alkyl hydroperoxide reductase
GII87_07835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_07850	COG0746	molybdenum cofactor guanylyltransferase activity
GII87_07855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII87_07860	COG0303	'Molybdopterin
GII87_07865	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII87_07870	COG0314	molybdopterin synthase activity
GII87_07875	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII87_07880	COG1132	(ABC) transporter
GII87_07885	COG1132	(ABC) transporter
GII87_07895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII87_07900	COG1136	(ABC) transporter
GII87_07905	COG0577	efflux transmembrane transporter activity
GII87_07910	COG1349	DNA-binding transcription factor activity
GII87_07915	COG1105	Belongs to the carbohydrate kinase PfkB family
GII87_07920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII87_07920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII87_07920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII87_07925	COG0681	Belongs to the peptidase S26 family
GII87_07935	COG0488	(ABC) transporter
GII87_07940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII87_07945	COG2309	aminopeptidase activity
GII87_07955	COG1077	Cell shape determining protein MreB Mrl
GII87_07960	COG2002	toxin-antitoxin pair type II binding
GII87_07965	COG3852	Histidine kinase
GII87_07970	COG2105	PFAM AIG2 family protein
GII87_07970	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII87_07975	COG0569	domain protein
GII87_07980	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII87_07985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII87_07995	COG0561	phosphatase activity
GII87_08000	COG0242	peptide deformylase activity
GII87_08010	COG0497	DNA recombination
GII87_08015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII87_08020	COG0022	dehydrogenase e1 component
GII87_08025	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII87_08030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII87_08035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_08045	COG1982	Orn Lys Arg decarboxylase major
GII87_08050	COG4476	Belongs to the UPF0223 family
GII87_08055	COG4493	Belongs to the UPF0637 family
GII87_08065	COG0483	inositol monophosphate 1-phosphatase activity
GII87_08075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII87_08095	COG1595	DNA-templated transcription, initiation
GII87_08125	COG4896	Protein conserved in bacteria
GII87_08135	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII87_08140	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII87_08145	COG2066	Belongs to the glutaminase family
GII87_08150	COG4838	Belongs to the UPF0358 family
GII87_08155	COG0772	Belongs to the SEDS family
GII87_08160	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII87_08165	COG1612	heme a metabolic process
GII87_08170	COG0109	protoheme IX farnesyltransferase activity
GII87_08175	COG2010	Cytochrome c
GII87_08175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII87_08180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII87_08185	COG1845	cytochrome c oxidase, subunit III
GII87_08190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII87_08195	COG3336	cytochrome c oxidase
GII87_08205	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII87_08210	COG2340	Cysteine-rich secretory protein family
GII87_08225	COG3679	Belongs to the UPF0342 family
GII87_08230	COG4471	UPF0298 protein
GII87_08235	COG0742	ribosomal rna small subunit methyltransferase
GII87_08240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII87_08245	COG3314	Sporulation integral membrane protein YlbJ
GII87_08250	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII87_08255	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII87_08260	COG1323	Belongs to the UPF0348 family
GII87_08270	COG1399	metal-binding, possibly nucleic acid-binding protein
GII87_08275	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GII87_08285	COG0454	-acetyltransferase
GII87_08290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII87_08295	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII87_08300	COG2001	Belongs to the MraZ family
GII87_08305	COG0275	rRNA processing
GII87_08310	COG4839	cell division protein FtsL
GII87_08320	COG0768	penicillin binding
GII87_08325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII87_08330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII87_08335	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII87_08340	COG0772	Belongs to the SEDS family
GII87_08345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII87_08350	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII87_08355	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII87_08360	COG3879	Bacterial protein of unknown function (DUF881)
GII87_08365	COG3879	Bacterial protein of unknown function (DUF881)
GII87_08370	COG3856	small basic protein
GII87_08375	COG0849	cell division
GII87_08380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII87_08385	COG1404	Belongs to the peptidase S8 family
GII87_08385	COG4412	M6 family metalloprotease domain protein
GII87_08395	COG1191	sigma factor activity
GII87_08400	COG1191	sigma factor activity
GII87_08405	COG1119	ATPase activity
GII87_08410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII87_08415	COG1873	PFAM PRC-barrel domain
GII87_08425	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII87_08430	COG1799	cell septum assembly
GII87_08435	COG0762	integral membrane protein
GII87_08440	COG2302	S4 RNA-binding domain
GII87_08445	COG3599	regulation of cell shape
GII87_08450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII87_08455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII87_08460	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII87_08465	COG0564	pseudouridine synthase activity
GII87_08470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII87_08475	COG2233	PERMEase
GII87_08480	COG0540	Belongs to the ATCase OTCase family
GII87_08485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII87_08490	COG0505	Belongs to the CarA family
GII87_08495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII87_08500	COG0543	2 iron, 2 sulfur cluster binding
GII87_08505	COG0167	dihydroorotate dehydrogenase activity
GII87_08510	COG0284	orotidine-5'-phosphate decarboxylase activity
GII87_08515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII87_08520	COG0175	sulfate reduction
GII87_08525	COG0306	phosphate transporter
GII87_08530	COG2046	Belongs to the sulfate adenylyltransferase family
GII87_08535	COG0529	Catalyzes the synthesis of activated sulfate
GII87_08540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII87_08545	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII87_08550	COG1648	precorrin-2 dehydrogenase activity
GII87_08560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII87_08565	COG1561	YicC-like family, N-terminal region
GII87_08570	COG2052	Domain of unknown function (DUF370)
GII87_08575	COG0194	GDP metabolic process
GII87_08580	COG1758	RNA polymerase activity
GII87_08585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII87_08590	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII87_08595	COG0242	peptide deformylase activity
GII87_08600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII87_08605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII87_08605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII87_08610	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII87_08615	COG0631	protein serine/threonine phosphatase activity
GII87_08620	COG0515	serine threonine protein kinase
GII87_08620	COG2815	serine threonine protein kinase
GII87_08625	COG1162	GTPase activity
GII87_08630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII87_08635	COG1564	THIamine pyrophosphokinase
GII87_08645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII87_08650	COG1302	Protein conserved in bacteria
GII87_08655	COG1461	Dihydroxyacetone kinase
GII87_08660	COG1760	l-serine dehydratase
GII87_08665	COG1760	l-serine dehydratase
GII87_08670	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII87_08675	COG1349	DNA-binding transcription factor activity
GII87_08675	COG2050	protein possibly involved in aromatic compounds catabolism
GII87_08680	COG0416	fatty acid biosynthetic process
GII87_08685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII87_08690	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_08695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII87_08700	COG0571	ribonuclease III activity
GII87_08705	COG1196	nuclear chromosome segregation
GII87_08710	COG0552	protein localization to endoplasmic reticulum
GII87_08720	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII87_08725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII87_08730	COG0228	four-way junction DNA binding
GII87_08735	COG1837	Belongs to the UPF0109 family
GII87_08745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII87_08750	COG0336	Belongs to the RNA methyltransferase TrmD family
GII87_08755	COG0335	large ribosomal subunit rRNA binding
GII87_08760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII87_08765	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII87_08775	COG2257	FlhB HrpN YscU SpaS Family
GII87_08780	COG0045	succinate-CoA ligase (ADP-forming) activity
GII87_08785	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII87_08790	COG0758	DNA mediated transformation
GII87_08795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII87_08800	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII87_08805	COG4974	Belongs to the 'phage' integrase family
GII87_08810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII87_08815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII87_08820	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII87_08825	COG1815	bacterial-type flagellum-dependent cell motility
GII87_08830	COG1558	bacterial-type flagellum-dependent cell motility
GII87_08835	COG1677	Flagellar hook-basal body complex protein FliE
GII87_08840	COG1766	The M ring may be actively involved in energy transduction
GII87_08845	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII87_08850	COG1317	bacterial-type flagellum organization
GII87_08855	COG1157	protein secretion by the type III secretion system
GII87_08860	COG2882	bacterial-type flagellum organization
GII87_08865	COG3334	PFAM MgtE intracellular
GII87_08870	COG3144	bacterial-type flagellum assembly
GII87_08875	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII87_08880	COG4786	Flagellar basal body rod
GII87_08885	COG1582	Flagellar protein (FlbD)
GII87_08890	COG1580	Controls the rotational direction of flagella during chemotaxis
GII87_08895	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII87_08900	COG1776	CheC inhibitor of MCP methylation
GII87_08900	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII87_08905	COG2201	protein-glutamate methylesterase activity
GII87_08910	COG3190	flagellar
GII87_08915	COG1338	Plays a role in the flagellum-specific transport system
GII87_08920	COG1987	bacterial-type flagellum assembly
GII87_08925	COG1684	flagellar biosynthetic protein fliR
GII87_08930	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII87_08935	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII87_08940	COG1419	protein localization to endoplasmic reticulum
GII87_08945	COG0455	bacterial-type flagellum organization
GII87_08950	COG2201	protein-glutamate methylesterase activity
GII87_08955	COG2198	Histidine kinase
GII87_08955	COG0643	Histidine kinase
GII87_08960	COG0835	chemotaxis
GII87_08965	COG1776	CheC inhibitor of MCP methylation
GII87_08970	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII87_08975	COG1191	sigma factor activity
GII87_08985	COG0052	Belongs to the universal ribosomal protein uS2 family
GII87_08990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII87_08995	COG0528	UMP kinase activity
GII87_09000	COG0233	cytoplasmic translational termination
GII87_09005	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII87_09010	COG4589	Belongs to the CDS family
GII87_09015	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII87_09020	COG0750	zinc metalloprotease
GII87_09025	COG0442	prolyl-tRNA aminoacylation
GII87_09030	COG2176	DNA-directed DNA polymerase activity
GII87_09035	COG0779	Required for maturation of 30S ribosomal subunits
GII87_09040	COG0195	Participates in both transcription termination and antitermination
GII87_09045	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII87_09050	COG1358	cellular component organization or biogenesis
GII87_09055	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII87_09060	COG1550	Protein conserved in bacteria
GII87_09065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII87_09070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII87_09075	COG0196	riboflavin kinase activity
GII87_09080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII87_09085	COG1185	polyribonucleotide nucleotidyltransferase activity
GII87_09090	COG0726	polysaccharide deacetylase
GII87_09095	COG0612	Peptidase, M16
GII87_09100	COG1873	PFAM PRC-barrel domain
GII87_09105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII87_09110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII87_09115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII87_09120	COG0527	aspartate kinase activity
GII87_09125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII87_09130	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII87_09135	COG0740	serine-type endopeptidase activity
GII87_09145	COG1674	ftsk spoiiie
GII87_09145	COG4980	gas vesicle protein
GII87_09150	COG2188	Transcriptional regulator
GII87_09155	COG2814	Major facilitator Superfamily
GII87_09160	COG0612	Peptidase, M16
GII87_09165	COG0612	Peptidase, M16
GII87_09170	COG0300	oxidoreductase activity
GII87_09185	COG1426	Protein conserved in bacteria
GII87_09190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII87_09195	COG1058	Belongs to the CinA family
GII87_09195	COG1546	Belongs to the CinA family
GII87_09200	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII87_09205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII87_09210	COG1418	mRNA catabolic process
GII87_09215	COG1692	metallophosphoesterase
GII87_09220	COG2359	stage V sporulation protein S
GII87_09225	COG1063	alcohol dehydrogenase
GII87_09230	COG0156	8-amino-7-oxononanoate synthase activity
GII87_09235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII87_09240	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII87_09250	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII87_09255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII87_09270	COG3226	Transcriptional regulator
GII87_09275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII87_09285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII87_09290	COG3321	synthase
GII87_09295	COG2070	2-Nitropropane dioxygenase
GII87_09295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII87_09300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII87_09305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII87_09310	COG3425	synthase
GII87_09315	COG1024	Enoyl-CoA hydratase
GII87_09320	COG1024	Enoyl-CoA hydratase
GII87_09325	COG0300	oxidoreductase activity
GII87_09325	COG3321	synthase
GII87_09325	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_09325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_09325	COG0318	PFAM AMP-dependent synthetase and ligase
GII87_09330	COG3321	synthase
GII87_09330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII87_09330	COG4221	oxidoreductase activity
GII87_09330	COG0300	oxidoreductase activity
GII87_09335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII87_09335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII87_09335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_09335	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_09335	COG3321	synthase
GII87_09340	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_09340	COG3321	synthase
GII87_09340	COG4221	oxidoreductase activity
GII87_09340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_09345	COG3321	synthase
GII87_09345	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII87_09345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GII87_09345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII87_09350	COG2124	cytochrome p450
GII87_09360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII87_09365	COG1404	Belongs to the peptidase S8 family
GII87_09370	COG4195	phage-related replication protein
GII87_09375	COG1764	response to oxidative stress
GII87_09380	COG2076	Multidrug Resistance protein
GII87_09385	COG2076	Multidrug Resistance protein
GII87_09400	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII87_09405	COG1923	regulation of RNA biosynthetic process
GII87_09420	COG1780	Probably involved in ribonucleotide reductase function
GII87_09425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII87_09430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII87_09435	COG4112	unkown
GII87_09440	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII87_09445	COG0464	growth
GII87_09450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII87_09455	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII87_09460	COG0789	Transcriptional regulator
GII87_09465	COG0174	glutamine synthetase
GII87_09485	COG4282	regulation of fungal-type cell wall biogenesis
GII87_09495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII87_09525	COG0135	phosphoribosylanthranilate isomerase activity
GII87_09530	COG2211	Major facilitator Superfamily
GII87_09535	COG3507	Belongs to the glycosyl hydrolase 43 family
GII87_09540	COG1940	carbohydrate kinase activity
GII87_09545	COG2115	Belongs to the xylose isomerase family
GII87_09550	COG1070	Carbohydrate kinase
GII87_09560	COG1525	nuclease
GII87_09565	COG2814	Major facilitator Superfamily
GII87_09570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII87_09580	COG0756	dUTP diphosphatase activity
GII87_09595	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII87_09620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII87_09635	COG3832	glyoxalase III activity
GII87_09645	COG0697	spore germination
GII87_09650	COG0531	amino acid
GII87_09680	COG4195	phage-related replication protein
GII87_09690	COG0346	lactoylglutathione lyase activity
GII87_09695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII87_09700	COG1388	LysM domain
GII87_09705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII87_09710	COG4224	UPF0291 protein
GII87_09715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII87_09725	COG3763	UPF0154 protein
GII87_09735	COG0785	Cytochrome C biogenesis protein
GII87_09740	COG2201	protein-glutamate methylesterase activity
GII87_09745	COG4846	Membrane protein involved in cytochrome C biogenesis
GII87_09755	COG0071	Belongs to the small heat shock protein (HSP20) family
GII87_09770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII87_09775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_09795	COG0824	Thioesterase
GII87_09805	COG4841	protein insertion into membrane
GII87_09810	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII87_09815	COG1832	CoA-binding protein
GII87_09820	COG0187	DNA topoisomerase II activity
GII87_09825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII87_09835	COG1115	amino acid carrier protein
GII87_09840	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GII87_09850	COG5520	Belongs to the glycosyl hydrolase 30 family
GII87_09855	COG3507	Belongs to the glycosyl hydrolase 43 family
GII87_09860	COG2246	polysaccharide biosynthetic process
GII87_09865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII87_09870	COG0586	Pfam SNARE associated Golgi protein
GII87_09875	COG2404	hydrolase activity, acting on ester bonds
GII87_09880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII87_09885	COG1024	Enoyl-CoA hydratase
GII87_09890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII87_09895	COG0511	ligase activity, forming carbon-carbon bonds
GII87_09900	COG0439	Biotin carboxylase
GII87_09905	COG0318	PFAM AMP-dependent synthetase and ligase
GII87_09910	COG1960	acyl-CoA dehydrogenase activity
GII87_09925	COG1649	PFAM Uncharacterised BCR, COG1649
GII87_09935	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII87_09935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_09940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_09945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_09950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_09955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_09960	COG2027	D-alanyl-D-alanine carboxypeptidase
GII87_09965	COG2017	converts alpha-aldose to the beta-anomer
GII87_09970	COG0534	Mate efflux family protein
GII87_09985	COG0582	viral genome integration into host DNA
GII87_09990	COG0166	Belongs to the GPI family
GII87_09995	COG0405	Gamma-glutamyltransferase
GII87_10000	COG0583	DNA-binding transcription factor activity
GII87_10005	COG0604	alcohol dehydrogenase
GII87_10010	COG0493	'glutamate synthase
GII87_10015	COG0067	glutamate synthase
GII87_10015	COG0070	glutamate synthase
GII87_10015	COG0069	glutamate synthase activity
GII87_10020	COG0583	DNA-binding transcription factor activity
GII87_10025	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII87_10030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII87_10040	COG0300	oxidoreductase activity
GII87_10045	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII87_10055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII87_10060	COG2814	Major facilitator Superfamily
GII87_10065	COG1070	Carbohydrate kinase
GII87_10070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII87_10075	COG0243	molybdopterin cofactor binding
GII87_10105	COG5278	phosphoserine phosphatase activity
GII87_10105	COG0840	transmembrane signaling receptor activity
GII87_10110	COG2368	4-hydroxyphenylacetate
GII87_10115	COG4305	rare lipoprotein A
GII87_10120	COG3619	membrane
GII87_10125	COG3866	Pectate lyase
GII87_10130	COG2135	peptidase activity
GII87_10140	COG2140	Oxalate decarboxylase
GII87_10155	COG0456	acetyltransferase
GII87_10175	COG2720	vancomycin resistance protein
GII87_10185	COG3655	Transcriptional regulator
GII87_10190	COG3739	integral membrane protein
GII87_10195	COG0583	DNA-binding transcription factor activity
GII87_10200	COG0697	spore germination
GII87_10210	COG0693	protein deglycase activity
GII87_10215	COG2367	Beta-lactamase
GII87_10240	COG3848	Pyruvate phosphate dikinase
GII87_10240	COG0574	Belongs to the PEP-utilizing enzyme family
GII87_10245	COG0726	polysaccharide deacetylase
GII87_10250	COG2314	TM2 domain
GII87_10255	COG1396	sequence-specific DNA binding
GII87_10270	COG2135	peptidase activity
GII87_10305	COG0457	Tetratricopeptide repeat
GII87_10330	COG5290	Psort location Cytoplasmic, score
GII87_10355	COG5444	nuclease activity
GII87_10360	COG4282	regulation of fungal-type cell wall biogenesis
GII87_10365	COG1231	oxidoreductase activity
GII87_10370	COG5434	Belongs to the glycosyl hydrolase 28 family
GII87_10375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII87_10380	COG0662	Cupin 2, conserved barrel domain protein
GII87_10380	COG2207	Transcriptional regulator
GII87_10385	COG0456	acetyltransferase
GII87_10390	COG1309	transcriptional regulator
GII87_10395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII87_10400	COG3708	Transcriptional regulator
GII87_10405	COG2378	regulation of single-species biofilm formation
GII87_10415	COG0640	Transcriptional regulator
GII87_10420	COG0741	lytic transglycosylase activity
GII87_10425	COG2322	membrane
GII87_10440	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII87_10445	COG3239	Fatty acid desaturase
GII87_10450	COG4585	Histidine kinase
GII87_10455	COG2197	response regulator
GII87_10460	COG1388	LysM domain
GII87_10460	COG3584	3D domain protein
GII87_10465	COG0514	ATP-dependent DNA helicase (RecQ)
GII87_10475	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII87_10480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII87_10495	COG0071	Belongs to the small heat shock protein (HSP20) family
GII87_10520	COG1012	belongs to the aldehyde dehydrogenase family
GII87_10525	COG1657	PFAM Prenyltransferase squalene oxidase
GII87_10530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII87_10535	COG0733	neurotransmitter:sodium symporter activity
GII87_10540	COG0385	Bile acid
GII87_10545	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII87_10550	COG0567	Dehydrogenase, E1 component
GII87_10555	COG4548	von Willebrand factor, type A
GII87_10560	COG0714	Associated with various cellular activities
GII87_10565	COG2032	superoxide dismutase activity
GII87_10570	COG1388	LysM domain
GII87_10570	COG0791	NLP P60 protein
GII87_10575	COG1819	glycosyl
GII87_10580	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII87_10585	COG0534	Mate efflux family protein
GII87_10590	COG1366	Belongs to the anti-sigma-factor antagonist family
GII87_10595	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII87_10600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII87_10610	COG2962	Rard protein
GII87_10625	COG2610	gluconate transmembrane transporter activity
GII87_10630	COG1942	4-Oxalocrotonate Tautomerase
GII87_10635	COG1733	regulation of RNA biosynthetic process
GII87_10640	COG0778	Nitroreductase
GII87_10645	COG0400	carboxylic ester hydrolase activity
GII87_10650	COG0346	lactoylglutathione lyase activity
GII87_10660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII87_10665	COG3409	Peptidoglycan-binding domain 1 protein
GII87_10665	COG0793	Belongs to the peptidase S41A family
GII87_10670	COG2226	methyltransferase
GII87_10680	COG1876	peptidase activity
GII87_10685	COG0813	purine-nucleoside phosphorylase activity
GII87_10700	COG0671	phosphoesterase, PA-phosphatase related
GII87_10720	COG4479	Belongs to the UPF0346 family
GII87_10730	COG1509	lysine 2,3-aminomutase activity
GII87_10735	COG0456	acetyltransferase
GII87_10740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII87_10745	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII87_10750	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII87_10755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII87_10770	COG0456	acetyltransferase
GII87_10775	COG0463	Glycosyl transferase, family 2
GII87_10790	COG4641	Protein conserved in bacteria
GII87_10795	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII87_10800	COG1086	Polysaccharide biosynthesis protein
GII87_10810	COG3331	DNA recombination
GII87_10865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII87_10900	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GII87_10905	COG0756	dUTP diphosphatase activity
GII87_10910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_10930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII87_10930	COG1372	Participates in initiation and elongation during chromosome replication
GII87_10935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII87_10935	COG1372	Participates in initiation and elongation during chromosome replication
GII87_10940	COG1780	Probably involved in ribonucleotide reductase function
GII87_11030	COG0270	DNA (cytosine-5-)-methyltransferase activity
GII87_11040	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GII87_11045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII87_11070	COG3584	3D domain protein
GII87_11075	COG0587	DNA-directed DNA polymerase activity
GII87_11080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII87_11085	COG0358	DNA primase activity
GII87_11090	COG0305	Participates in initiation and elongation during chromosome replication
GII87_11100	COG2887	Belongs to the helicase family. UvrD subfamily
GII87_11130	COG5434	Belongs to the glycosyl hydrolase 28 family
GII87_11130	COG3420	alginic acid biosynthetic process
GII87_11135	COG4195	phage-related replication protein
GII87_11150	COG2135	peptidase activity
GII87_11155	COG1793	dna ligase
GII87_11210	COG4474	Belongs to the UPF0398 family
GII87_11220	COG1388	LysM domain
GII87_11240	COG3645	SOS response
GII87_11240	COG3646	Phage regulatory protein
GII87_11295	COG3655	Transcriptional regulator
GII87_11310	COG0582	viral genome integration into host DNA
GII87_11390	COG3655	Transcriptional regulator
GII87_11430	COG1395	domain, Protein
GII87_11445	COG0776	regulation of translation
GII87_11480	COG4373	Mu-like prophage FluMu protein gp28
GII87_11580	COG0582	viral genome integration into host DNA
GII87_11610	COG1196	nuclear chromosome segregation
GII87_11610	COG0741	lytic transglycosylase activity
GII87_11610	COG0739	heme binding
GII87_11620	COG2433	Pfam Transposase IS66
GII87_11630	COG4632	Exopolysaccharide biosynthesis protein
GII87_11630	COG5434	Belongs to the glycosyl hydrolase 28 family
GII87_11645	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII87_11660	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII87_11665	COG0463	Glycosyl transferase, family 2
GII87_11670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_11675	COG2274	protein secretion by the type I secretion system
GII87_11675	COG3271	cysteine-type peptidase activity
GII87_11690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII87_11720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII87_11735	COG5444	nuclease activity
GII87_11740	COG4282	regulation of fungal-type cell wall biogenesis
GII87_11755	COG1525	nuclease
GII87_11765	COG2746	aminoglycoside 3-N-acetyltransferase activity
GII87_11790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII87_11795	COG1086	Polysaccharide biosynthesis protein
GII87_11800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII87_11805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII87_11810	COG1846	Transcriptional regulator
GII87_11815	COG0534	Mate efflux family protein
GII87_11825	COG4698	Protein conserved in bacteria
GII87_11830	COG2755	lipolytic protein G-D-S-L family
GII87_11835	COG1999	signal sequence binding
GII87_11845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII87_11850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII87_11855	COG1272	protein, Hemolysin III
GII87_11860	COG0204	Acyl-transferase
GII87_11865	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII87_11870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII87_11875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII87_11885	COG2136	Putative SAM-dependent methyltransferase
GII87_11885	COG2521	methyltransferase
GII87_11895	COG0129	dihydroxy-acid dehydratase activity
GII87_11900	COG1413	lyase activity
GII87_11905	COG1418	mRNA catabolic process
GII87_11910	COG0386	Belongs to the glutathione peroxidase family
GII87_11915	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII87_11920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII87_11930	COG1278	Cold shock
GII87_11950	COG0328	RNA-DNA hybrid ribonuclease activity
GII87_11955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII87_11960	COG0328	RNA-DNA hybrid ribonuclease activity
GII87_11970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII87_11985	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII87_11995	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII87_12000	COG3424	synthase
GII87_12005	COG2233	PERMEase
GII87_12010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII87_12015	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII87_12025	COG0800	Aldolase
GII87_12030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII87_12035	COG1609	Transcriptional regulator
GII87_12040	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII87_12045	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_12050	COG1199	ATP-dependent helicase activity
GII87_12065	COG0116	Belongs to the methyltransferase superfamily
GII87_12080	COG4474	Belongs to the UPF0398 family
GII87_12095	COG3359	exonuclease
GII87_12100	COG1111	helicase
GII87_12100	COG1205	dead DEAH box helicase
GII87_12105	COG2190	(PTS) system
GII87_12110	COG0071	Belongs to the small heat shock protein (HSP20) family
GII87_12145	COG3331	DNA recombination
GII87_12150	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII87_12150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII87_12160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII87_12165	COG3935	DnaD domain protein
GII87_12170	COG0017	Asparaginyl-tRNA synthetase
GII87_12175	COG0436	Aminotransferase
GII87_12180	COG5353	protein conserved in bacteria
GII87_12190	COG1199	ATP-dependent helicase activity
GII87_12190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII87_12195	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII87_12200	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII87_12205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII87_12210	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII87_12210	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII87_12215	COG0617	tRNA 3'-terminal CCA addition
GII87_12220	COG0438	transferase activity, transferring glycosyl groups
GII87_12225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII87_12230	COG1803	Methylglyoxal synthase
GII87_12235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII87_12240	COG1694	Mazg nucleotide pyrophosphohydrolase
GII87_12245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII87_12255	COG4347	Protein of unknown function (DUF1405)
GII87_12260	COG2010	Cytochrome c
GII87_12260	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII87_12265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII87_12270	COG0723	plastoquinol--plastocyanin reductase activity
GII87_12280	COG5582	Belongs to the UPF0302 family
GII87_12285	COG0457	Tetratricopeptide repeat
GII87_12290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII87_12295	COG0287	Prephenate dehydrogenase
GII87_12300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GII87_12305	COG0159	tryptophan synthase activity
GII87_12310	COG0133	tryptophan synthase activity
GII87_12315	COG0135	phosphoribosylanthranilate isomerase activity
GII87_12325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII87_12330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII87_12335	COG4401	Chorismate mutase type I
GII87_12340	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII87_12345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII87_12350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII87_12355	COG0105	UTP biosynthetic process
GII87_12360	COG0142	geranyltranstransferase activity
GII87_12365	COG2226	methyltransferase
GII87_12370	COG0142	geranyltranstransferase activity
GII87_12380	COG0302	gtp cyclohydrolase
GII87_12385	COG0776	regulation of translation
GII87_12390	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII87_12405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII87_12410	COG1160	GTP binding
GII87_12435	COG1304	FMN binding
GII87_12440	COG0539	negative regulation of cytoplasmic translation
GII87_12445	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII87_12455	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII87_12460	COG2959	enzyme of heme biosynthesis
GII87_12465	COG3409	Peptidoglycan-binding domain 1 protein
GII87_12465	COG3773	Cell wall hydrolase
GII87_12470	COG2339	peptidase activity
GII87_12475	COG0492	ferredoxin-NADP+ reductase activity
GII87_12480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII87_12485	COG4862	establishment of competence for transformation
GII87_12490	COG1408	metallophosphoesterase
GII87_12500	COG1388	LysM domain
GII87_12505	COG1266	CAAX protease self-immunity
GII87_12510	COG0514	ATP-dependent DNA helicase (RecQ)
GII87_12515	COG4955	Helix-turn-helix domain
GII87_12520	COG1141	Ferredoxin
GII87_12525	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII87_12530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII87_12535	COG0710	3-dehydroquinate dehydratase activity
GII87_12545	COG1595	DNA-templated transcription, initiation
GII87_12550	COG5002	protein histidine kinase activity
GII87_12555	COG0745	RESPONSE REGULATOR receiver
GII87_12560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII87_12565	COG1333	cytochrome c biogenesis protein
GII87_12570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_12575	COG1187	pseudouridine synthase activity
GII87_12580	COG0700	Nucleoside recognition
GII87_12585	COG2715	membrane protein required for spore maturation
GII87_12590	COG1686	Belongs to the peptidase S11 family
GII87_12600	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII87_12605	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII87_12610	COG1547	Domain of unknown function (DUF309)
GII87_12615	COG0456	acetyltransferase
GII87_12620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII87_12625	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII87_12625	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII87_12630	COG0307	riboflavin synthase, alpha
GII87_12635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII87_12635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII87_12645	COG0681	Belongs to the peptidase S26 family
GII87_12655	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII87_12670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII87_12675	COG4086	secreted protein
GII87_12680	COG0019	diaminopimelate decarboxylase activity
GII87_12685	COG0697	spore germination
GII87_12700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII87_12720	COG1191	sigma factor activity
GII87_12725	COG2172	sigma factor antagonist activity
GII87_12730	COG1366	Belongs to the anti-sigma-factor antagonist family
GII87_12735	COG1686	Belongs to the peptidase S11 family
GII87_12740	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII87_12745	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII87_12750	COG4974	Belongs to the 'phage' integrase family
GII87_12760	COG0735	belongs to the Fur family
GII87_12765	COG1300	Membrane
GII87_12775	COG0281	malic enzyme
GII87_12780	COG1757	Na H antiporter
GII87_12785	COG1027	Aspartate ammonia-lyase
GII87_12790	COG0252	asparaginase activity
GII87_12795	COG1396	sequence-specific DNA binding
GII87_12800	COG1379	DNA repair
GII87_12805	COG0494	nUDIX hydrolase
GII87_12815	COG0667	Aldo Keto reductase
GII87_12825	COG1073	alpha beta
GII87_12835	COG4918	Iron-sulphur cluster biosynthesis
GII87_12840	COG0456	acetyltransferase
GII87_12840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII87_12845	COG2329	Antibiotic biosynthesis monooxygenase
GII87_12850	COG0456	acetyltransferase
GII87_12860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII87_12870	COG2211	Major facilitator Superfamily
GII87_12875	COG0346	lactoylglutathione lyase activity
GII87_12880	COG1072	(Pantothenic acid kinase))
GII87_12885	COG3048	D-serine ammonia-lyase activity
GII87_12890	COG0300	oxidoreductase activity
GII87_12895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII87_12900	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII87_12905	COG4187	Peptidase family M20/M25/M40
GII87_12910	COG1902	pentaerythritol trinitrate reductase activity
GII87_12915	COG0596	Alpha beta hydrolase
GII87_12925	COG1234	tRNA 3'-trailer cleavage
GII87_12930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII87_12935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII87_12940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII87_12950	COG0706	membrane insertase activity
GII87_12955	COG3361	conserved protein (COG2071)
GII87_12960	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII87_12965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII87_12970	COG0346	lactoylglutathione lyase activity
GII87_12980	COG1376	ErfK ybiS ycfS ynhG family protein
GII87_12985	COG4129	membrane
GII87_12990	COG1126	abc transporter atp-binding protein
GII87_12995	COG0765	amino acid transport
GII87_13000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII87_13010	COG1597	lipid kinase activity
GII87_13015	COG2814	Major facilitator Superfamily
GII87_13020	COG0789	Transcriptional regulator
GII87_13020	COG4978	Transcriptional regulator
GII87_13025	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII87_13030	COG0022	dehydrogenase e1 component
GII87_13035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII87_13040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII87_13045	COG3426	butyrate kinase activity
GII87_13050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII87_13055	COG0280	phosphate acetyltransferase
GII87_13060	COG3290	protein histidine kinase activity
GII87_13060	COG3829	transcription factor binding
GII87_13070	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII87_13075	COG2079	MmgE PrpD family protein
GII87_13080	COG0372	Belongs to the citrate synthase family
GII87_13085	COG1960	acyl-CoA dehydrogenase activity
GII87_13090	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII87_13095	COG0183	Belongs to the thiolase family
GII87_13100	COG0584	glycerophosphoryl diester phosphodiesterase
GII87_13105	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII87_13120	COG1902	pentaerythritol trinitrate reductase activity
GII87_13125	COG0745	RESPONSE REGULATOR receiver
GII87_13130	COG0750	zinc metalloprotease
GII87_13135	COG0497	DNA recombination
GII87_13140	COG1438	arginine binding
GII87_13145	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII87_13150	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII87_13155	COG0142	geranyltranstransferase activity
GII87_13160	COG1722	exodeoxyribonuclease VII activity
GII87_13165	COG1570	exodeoxyribonuclease VII activity
GII87_13170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII87_13175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII87_13180	COG1302	Protein conserved in bacteria
GII87_13185	COG0439	Biotin carboxylase
GII87_13190	COG0511	ligase activity, forming carbon-carbon bonds
GII87_13230	COG3854	ATPases associated with a variety of cellular activities
GII87_13240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII87_13245	COG0006	proline dipeptidase activity
GII87_13250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII87_13260	COG3872	metal-dependent enzyme
GII87_13270	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII87_13275	COG1321	iron dependent repressor
GII87_13280	COG0095	Lipoate-protein ligase
GII87_13285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII87_13290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII87_13295	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII87_13300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII87_13305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII87_13320	COG1396	sequence-specific DNA binding
GII87_13330	COG0681	Belongs to the peptidase S26 family
GII87_13355	COG4940	Competence protein ComGF
GII87_13365	COG4970	Tfp pilus assembly protein FimT
GII87_13370	COG4537	Required for transformation and DNA binding
GII87_13375	COG1459	type II secretion system
GII87_13380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII87_13385	COG0598	Magnesium transport protein CorA
GII87_13390	COG1253	flavin adenine dinucleotide binding
GII87_13395	COG1366	Belongs to the anti-sigma-factor antagonist family
GII87_13405	COG1393	Belongs to the ArsC family
GII87_13415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII87_13425	COG0011	TIGRFAM Protein of
GII87_13435	COG2866	Carboxypeptidase
GII87_13440	COG1368	sulfuric ester hydrolase activity
GII87_13445	COG1940	carbohydrate kinase activity
GII87_13450	COG4483	Protein conserved in bacteria
GII87_13455	COG0457	Tetratricopeptide repeat
GII87_13455	COG0705	Rhomboid family
GII87_13465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII87_13470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII87_13475	COG0438	transferase activity, transferring glycosyl groups
GII87_13490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII87_13495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII87_13500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII87_13505	COG0581	inorganic phosphate transmembrane transporter activity
GII87_13510	COG0573	inorganic phosphate transmembrane transporter activity
GII87_13515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII87_13525	COG0477	Major facilitator Superfamily
GII87_13530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII87_13535	COG2839	Protein conserved in bacteria
GII87_13540	COG5521	maltodextrose utilization protein MalA
GII87_13550	COG1388	LysM domain
GII87_13555	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII87_13560	COG4709	membrane
GII87_13565	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII87_13570	COG0735	belongs to the Fur family
GII87_13575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII87_13585	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII87_13590	COG0513	Belongs to the DEAD box helicase family
GII87_13600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII87_13605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII87_13610	COG2384	SAM-dependent methyltransferase
GII87_13615	COG2010	Cytochrome c
GII87_13620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII87_13625	COG0358	DNA primase activity
GII87_13630	COG1671	Belongs to the UPF0178 family
GII87_13635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII87_13640	COG0517	IMP dehydrogenase activity
GII87_13645	COG0751	glycine-tRNA ligase activity
GII87_13650	COG0752	glycyl-tRNA synthetase alpha subunit
GII87_13655	COG1381	Involved in DNA repair and RecF pathway recombination
GII87_13665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII87_13670	COG0295	cytidine deaminase activity
GII87_13675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII87_13680	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII87_13685	COG1480	7TM receptor with intracellular HD hydrolase
GII87_13690	COG1702	phosphate starvation-inducible protein PhoH
GII87_13695	COG0561	phosphatase activity
GII87_13710	COG4864	UPF0365 protein
GII87_13715	COG1030	water channel activity
GII87_13720	COG1610	YqeY-like protein
GII87_13725	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GII87_13730	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII87_13735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII87_13740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII87_13745	COG2264	protein methyltransferase activity
GII87_13750	COG0484	heat shock protein binding
GII87_13755	COG0443	Heat shock 70 kDa protein
GII87_13760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII87_13765	COG1420	regulation of RNA biosynthetic process
GII87_13770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII87_13775	COG0481	GTPase activity
GII87_13785	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII87_13790	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII87_13795	COG0268	Binds directly to 16S ribosomal RNA
GII87_13800	COG1466	dna polymerase III delta subunit
GII87_13815	COG2333	competence protein COMEC
GII87_13815	COG0658	competence protein
GII87_13820	COG2131	deaminase
GII87_13825	COG1555	photosystem II stabilization
GII87_13825	COG1596	polysaccharide export
GII87_13830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII87_13835	COG2226	methyltransferase
GII87_13840	COG0799	negative regulation of ribosome biogenesis
GII87_13845	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII87_13850	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII87_13855	COG1534	Rna-binding protein
GII87_13860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII87_13865	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII87_13870	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII87_13880	COG2755	lipolytic protein G-D-S-L family
GII87_13885	COG3409	Peptidoglycan-binding domain 1 protein
GII87_13885	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII87_13890	COG0398	Pfam SNARE associated Golgi protein
GII87_13895	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GII87_13905	COG3209	COG3209 Rhs family protein
GII87_13915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII87_13920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII87_13925	COG0798	PFAM Bile acid sodium symporter
GII87_13930	COG0346	lactoylglutathione lyase activity
GII87_13935	COG0640	Transcriptional regulator
GII87_13940	COG3403	YqcI/YcgG family
GII87_13945	COG0457	Tetratricopeptide repeat
GII87_13960	COG5444	nuclease activity
GII87_13985	COG3409	Peptidoglycan-binding domain 1 protein
GII87_13985	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII87_13990	COG4824	toxin secretion phage lysis holin
GII87_14020	COG3778	Protein conserved in bacteria
GII87_14025	COG3299	homolog of phage Mu protein gp47
GII87_14030	COG3628	GPW Gp25 family protein
GII87_14040	COG4193	domain, Protein
GII87_14045	COG1652	LysM domain
GII87_14050	COG5280	Phage tail tape measure protein TP901
GII87_14050	COG3953	SLT domain
GII87_14115	COG4653	Phage capsid family
GII87_14120	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII87_14130	COG2369	cell adhesion
GII87_14135	COG5518	Phage portal protein
GII87_14140	COG1783	phage Terminase large subunit
GII87_14145	COG5484	DNA packaging
GII87_14155	COG3677	Transposase
GII87_14170	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GII87_14180	COG1484	DNA-dependent DNA replication
GII87_14185	COG3935	DnaD domain protein
GII87_14190	COG3723	Recombinational DNA repair protein, rece pathway
GII87_14195	COG5377	YqaJ viral recombinase family
GII87_14225	COG1476	TRANSCRIPTIONal
GII87_14230	COG3620	sequence-specific DNA binding
GII87_14240	COG0563	adenylate kinase activity
GII87_14245	COG2856	Zn peptidase
GII87_14270	COG3223	Belongs to the PsiE family
GII87_14275	COG0642	Histidine kinase
GII87_14275	COG5002	protein histidine kinase activity
GII87_14280	COG0745	RESPONSE REGULATOR receiver
GII87_14285	COG2311	Membrane
GII87_14295	COG0454	-acetyltransferase
GII87_14300	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII87_14310	COG0730	response to heat
GII87_14315	COG0425	Belongs to the sulfur carrier protein TusA family
GII87_14320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII87_14320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII87_14330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII87_14330	COG0425	Belongs to the sulfur carrier protein TusA family
GII87_14340	COG2210	Belongs to the sulfur carrier protein TusA family
GII87_14345	COG1937	Protein conserved in bacteria
GII87_14355	COG0662	Cupin 2, conserved barrel domain protein
GII87_14365	COG0789	Transcriptional regulator
GII87_14365	COG4978	Transcriptional regulator
GII87_14370	COG2814	Major facilitator Superfamily
GII87_14375	COG0456	acetyltransferase
GII87_14380	COG1253	flavin adenine dinucleotide binding
GII87_14390	COG0697	spore germination
GII87_14395	COG0583	DNA-binding transcription factor activity
GII87_14400	COG2072	flavoprotein involved in K transport
GII87_14405	COG1230	cation diffusion facilitator family transporter
GII87_14410	COG1942	4-Oxalocrotonate Tautomerase
GII87_14415	COG0583	DNA-binding transcription factor activity
GII87_14425	COG1114	Component of the transport system for branched-chain amino acids
GII87_14430	COG1687	branched-chain amino acid
GII87_14435	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII87_14440	COG1522	sequence-specific DNA binding
GII87_14445	COG2732	(Barnase) inhibitor
GII87_14450	COG2124	cytochrome p450
GII87_14460	COG1335	isochorismatase
GII87_14470	COG2318	DinB family
GII87_14480	COG2070	2-Nitropropane dioxygenase
GII87_14485	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII87_14510	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII87_14520	COG0667	Aldo Keto reductase
GII87_14525	COG2851	Citrate transporter
GII87_14530	COG0583	DNA-binding transcription factor activity
GII87_14535	COG2828	Protein conserved in bacteria
GII87_14540	COG3409	Peptidoglycan-binding domain 1 protein
GII87_14545	COG5566	PFAM Mor transcription activator
GII87_14550	COG0596	Alpha beta hydrolase
GII87_14555	COG4991	sh3 domain protein
GII87_14560	COG4991	sh3 domain protein
GII87_14570	COG0346	lactoylglutathione lyase activity
GII87_14580	COG5577	PFAM Coat F domain
GII87_14585	COG1063	alcohol dehydrogenase
GII87_14595	COG5577	PFAM Coat F domain
GII87_14600	COG0789	Transcriptional regulator
GII87_14610	COG1064	alcohol dehydrogenase
GII87_14615	COG0693	protein deglycase activity
GII87_14620	COG1621	beta-fructofuranosidase activity
GII87_14625	COG3716	PTS system mannose fructose sorbose family IID component
GII87_14630	COG3715	PTS system
GII87_14635	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_14640	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII87_14645	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII87_14645	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII87_14655	COG1113	amino acid transport
GII87_14660	COG1280	lysine exporter protein (LysE YggA)
GII87_14665	COG1378	Sugar-specific transcriptional regulator TrmB
GII87_14670	COG1595	DNA-templated transcription, initiation
GII87_14680	COG2755	lipolytic protein G-D-S-L family
GII87_14680	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GII87_14690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII87_14690	COG2124	cytochrome p450
GII87_14695	COG1309	transcriptional regulator
GII87_14700	COG2226	methyltransferase
GII87_14715	COG2116	formate transmembrane transporter activity
GII87_14720	COG5609	conserved protein (DUF2294)
GII87_14725	COG3383	formate dehydrogenase (NAD+) activity
GII87_14730	COG2427	Protein of unknown function (DUF1641)
GII87_14740	COG0626	cystathionine gamma-synthase activity
GII87_14745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII87_14750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII87_14755	COG2226	methyltransferase
GII87_14770	COG0768	penicillin binding
GII87_14775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII87_14780	COG0572	uridine kinase
GII87_14800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII87_14805	COG3906	Belongs to the UPF0473 family
GII87_14810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII87_14815	COG4472	Bacterial protein of unknown function (DUF965)
GII87_14820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII87_14825	COG0628	permease
GII87_14830	COG1126	abc transporter atp-binding protein
GII87_14835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII87_14840	COG0765	amino acid transport
GII87_14845	COG0765	amino acid transport
GII87_14860	COG3881	PFAM PRC-barrel domain
GII87_14865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII87_14870	COG0457	Tetratricopeptide repeat
GII87_14875	COG0482	sulfurtransferase activity
GII87_14880	COG1104	cysteine desulfurase activity
GII87_14885	COG1959	2 iron, 2 sulfur cluster binding
GII87_14890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII87_14895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII87_14905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII87_14910	COG0124	histidyl-tRNA synthetase
GII87_14920	COG4991	sh3 domain protein
GII87_14920	COG3103	Sh3 type 3 domain protein
GII87_14920	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII87_14925	COG1490	D-aminoacyl-tRNA deacylase activity
GII87_14930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII87_14935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII87_14940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII87_14940	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII87_14945	COG5416	Lipopolysaccharide assembly protein A domain
GII87_14950	COG0490	domain, Protein
GII87_14955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII87_14955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII87_14965	COG2244	polysaccharide biosynthetic process
GII87_14970	COG2323	membrane
GII87_14980	COG1862	Preprotein translocase
GII87_14985	COG0343	queuine tRNA-ribosyltransferase activity
GII87_14990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII87_15000	COG2255	four-way junction helicase activity
GII87_15005	COG0632	four-way junction helicase activity
GII87_15015	COG2814	Major facilitator Superfamily
GII87_15020	COG0673	inositol 2-dehydrogenase activity
GII87_15025	COG2112	serine threonine protein kinase
GII87_15045	COG1115	amino acid carrier protein
GII87_15050	COG0217	transcriptional regulatory protein
GII87_15060	COG1388	LysM domain
GII87_15065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII87_15070	COG0157	Belongs to the NadC ModD family
GII87_15075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII87_15080	COG1104	cysteine desulfurase activity
GII87_15085	COG1827	regulation of RNA biosynthetic process
GII87_15090	COG0077	Prephenate dehydratase
GII87_15095	COG4492	Belongs to the UPF0735 family
GII87_15100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII87_15105	COG3290	protein histidine kinase activity
GII87_15115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII87_15120	COG2868	ribosomal protein
GII87_15125	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII87_15130	COG1994	Peptidase M50
GII87_15135	COG0739	heme binding
GII87_15140	COG2894	cell division
GII87_15145	COG0850	regulation of cytokinetic process
GII87_15150	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII87_15155	COG1792	Involved in formation and maintenance of cell shape
GII87_15160	COG1077	Cell shape determining protein MreB Mrl
GII87_15165	COG2003	Belongs to the UPF0758 family
GII87_15170	COG0424	maF-like protein
GII87_15180	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII87_15185	COG0285	dihydrofolate synthase activity
GII87_15190	COG0525	valine-tRNA ligase activity
GII87_15200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII87_15205	COG1388	LysM domain
GII87_15210	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII87_15215	COG0113	porphobilinogen synthase activity
GII87_15220	COG1587	Uroporphyrinogen-III synthase
GII87_15225	COG0181	hydroxymethylbilane synthase activity
GII87_15230	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII87_15235	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII87_15245	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII87_15250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII87_15255	COG0470	DNA polymerase III
GII87_15255	COG1067	ATP-dependent peptidase activity
GII87_15260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII87_15265	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII87_15270	COG1477	protein flavinylation
GII87_15270	COG0457	Tetratricopeptide repeat
GII87_15275	COG0066	3-isopropylmalate dehydratase activity
GII87_15280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII87_15285	COG0473	3-isopropylmalate dehydrogenase activity
GII87_15290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII87_15295	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII87_15300	COG0440	acetolactate synthase activity
GII87_15305	COG0028	Belongs to the TPP enzyme family
GII87_15315	COG0454	-acetyltransferase
GII87_15320	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII87_15330	COG0622	Phosphoesterase
GII87_15335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII87_15340	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII87_15345	COG5401	PFAM Sporulation and spore germination
GII87_15350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII87_15355	COG1846	Transcriptional regulator
GII87_15360	COG2197	response regulator
GII87_15365	COG0824	Thioesterase
GII87_15370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII87_15375	COG1053	succinate dehydrogenase
GII87_15380	COG2009	succinate dehydrogenase
GII87_15385	COG1719	4-vinyl reductase, 4VR
GII87_15390	COG0527	aspartate kinase activity
GII87_15395	COG0322	excinuclease ABC activity
GII87_15400	COG3118	belongs to the thioredoxin family
GII87_15405	COG3534	alpha-L-arabinofuranosidase
GII87_15410	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII87_15415	COG2086	electron transfer activity
GII87_15420	COG1024	Enoyl-CoA hydratase
GII87_15425	COG1309	transcriptional regulator
GII87_15430	COG0318	PFAM AMP-dependent synthetase and ligase
GII87_15435	COG3766	membrane
GII87_15440	COG1193	negative regulation of DNA recombination
GII87_15445	COG1796	DNA polymerase
GII87_15445	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII87_15450	COG1286	toxin biosynthetic process
GII87_15455	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII87_15460	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII87_15465	COG0072	phenylalanine-tRNA ligase activity
GII87_15465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII87_15470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII87_15480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII87_15490	COG3835	regulator
GII87_15495	COG0277	FAD linked oxidase domain protein
GII87_15500	COG0247	lactate metabolic process
GII87_15505	COG0346	lactoylglutathione lyase activity
GII87_15515	COG1966	Carbon starvation protein
GII87_15520	COG3534	alpha-L-arabinofuranosidase
GII87_15525	COG0395	ABC-type sugar transport system, permease component
GII87_15530	COG1175	transmembrane transport
GII87_15535	COG1653	transport
GII87_15540	COG0371	Dehydrogenase
GII87_15545	COG0647	UMP catabolic process
GII87_15550	COG0235	Class ii aldolase
GII87_15555	COG1069	ribulokinase activity
GII87_15560	COG2160	L-arabinose isomerase activity
GII87_15565	COG3507	Belongs to the glycosyl hydrolase 43 family
GII87_15570	COG1363	Peptidase, m42
GII87_15580	COG3326	Membrane
GII87_15585	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII87_15590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII87_15595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII87_15605	COG1346	cytolysis
GII87_15610	COG1380	Effector of murein hydrolase LrgA
GII87_15615	COG3279	Response regulator of the LytR AlgR family
GII87_15620	COG3275	phosphorelay sensor kinase activity
GII87_15630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII87_15640	COG0398	Pfam SNARE associated Golgi protein
GII87_15645	COG1484	DNA-dependent DNA replication
GII87_15650	COG3611	Membrane attachment protein
GII87_15655	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII87_15660	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII87_15665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII87_15670	COG1733	regulation of RNA biosynthetic process
GII87_15675	COG2814	Major facilitator Superfamily
GII87_15680	COG0656	L-ascorbic acid biosynthetic process
GII87_15685	COG0237	dephospho-CoA kinase activity
GII87_15690	COG1971	Probably functions as a manganese efflux pump
GII87_15695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII87_15700	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII87_15700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII87_15705	COG5002	protein histidine kinase activity
GII87_15710	COG0745	RESPONSE REGULATOR receiver
GII87_15715	COG0039	L-malate dehydrogenase activity
GII87_15720	COG0538	isocitrate dehydrogenase activity
GII87_15725	COG0372	Belongs to the citrate synthase family
GII87_15730	COG2707	UPF0756 membrane protein
GII87_15735	COG0628	permease
GII87_15740	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII87_15745	COG0469	pyruvate kinase activity
GII87_15750	COG0205	6-phosphofructokinase activity
GII87_15755	COG0825	malonyl-CoA metabolic process
GII87_15760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII87_15765	COG0281	malic enzyme
GII87_15770	COG0587	DNA-directed DNA polymerase activity
GII87_15790	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII87_15800	COG4109	DRTGG domain
GII87_15805	COG0730	response to heat
GII87_15810	COG1473	amidohydrolase
GII87_15815	COG0196	riboflavin kinase activity
GII87_15820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII87_15825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII87_15830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII87_15835	COG1126	abc transporter atp-binding protein
GII87_15840	COG0765	amino acid transport
GII87_15845	COG0765	amino acid transport
GII87_15850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII87_15855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII87_15860	COG0454	-acetyltransferase
GII87_15865	COG0583	DNA-binding transcription factor activity
GII87_15870	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII87_15875	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_15885	COG0165	Argininosuccinate lyase
GII87_15890	COG0137	argininosuccinate synthase activity
GII87_15895	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII87_15900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII87_15910	COG0827	DNA restriction-modification system
GII87_15915	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII87_15920	COG3874	Sporulation protein YtfJ
GII87_15930	COG1714	RDD family
GII87_15935	COG0616	signal peptide processing
GII87_15940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII87_15945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII87_15950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII87_15960	COG0301	tRNA thio-modification
GII87_15965	COG1104	cysteine desulfurase activity
GII87_15970	COG1114	Component of the transport system for branched-chain amino acids
GII87_15975	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII87_15980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII87_15985	COG1309	transcriptional regulator
GII87_15990	COG1956	GAF domain-containing protein
GII87_15995	COG2203	Gaf domain
GII87_15995	COG2199	diguanylate cyclase activity
GII87_16005	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII87_16010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII87_16015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII87_16020	COG0454	-acetyltransferase
GII87_16025	COG0517	IMP dehydrogenase activity
GII87_16030	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII87_16035	COG1360	Flagellar Motor Protein
GII87_16040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII87_16045	COG1609	Transcriptional regulator
GII87_16050	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII87_16050	COG1605	Chorismate mutase
GII87_16055	COG3118	belongs to the thioredoxin family
GII87_16060	COG4980	gas vesicle protein
GII87_16065	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII87_16070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII87_16075	COG1674	ftsk spoiiie
GII87_16080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII87_16085	COG4848	Belongs to the UPF0354 family
GII87_16090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_16105	COG1363	Peptidase, m42
GII87_16110	COG5584	Small secreted protein
GII87_16115	COG0281	malic enzyme
GII87_16120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII87_16125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII87_16135	COG0510	thiamine kinase activity
GII87_16140	COG1523	belongs to the glycosyl hydrolase 13 family
GII87_16145	COG1597	lipid kinase activity
GII87_16155	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII87_16160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII87_16165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII87_16170	COG2252	PERMEase
GII87_16175	COG4473	ABC transporter
GII87_16180	COG1131	(ABC) transporter
GII87_16185	COG1349	DNA-binding transcription factor activity
GII87_16190	COG1187	pseudouridine synthase activity
GII87_16195	COG2244	polysaccharide biosynthetic process
GII87_16200	COG2081	HI0933 family
GII87_16205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII87_16215	COG5578	integral membrane protein
GII87_16220	COG0673	inositol 2-dehydrogenase activity
GII87_16225	COG1653	transport
GII87_16230	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII87_16235	COG4209	transmembrane transport
GII87_16240	COG2207	Transcriptional regulator
GII87_16245	COG1653	transport
GII87_16250	COG0395	ABC-type sugar transport system, permease component
GII87_16255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII87_16260	COG2124	cytochrome p450
GII87_16265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII87_16270	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GII87_16275	COG0156	8-amino-7-oxononanoate synthase activity
GII87_16280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII87_16285	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GII87_16290	COG1073	alpha beta
GII87_16315	COG1486	melibiose metabolic process
GII87_16320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII87_16325	COG0495	leucyl-tRNA aminoacylation
GII87_16335	COG2202	Pas domain
GII87_16335	COG1366	Belongs to the anti-sigma-factor antagonist family
GII87_16340	COG2814	Major facilitator Superfamily
GII87_16345	COG2433	Pfam Transposase IS66
GII87_16350	COG0577	efflux transmembrane transporter activity
GII87_16355	COG1136	(ABC) transporter
GII87_16360	COG2205	protein histidine kinase activity
GII87_16365	COG0745	RESPONSE REGULATOR receiver
GII87_16370	COG0577	efflux transmembrane transporter activity
GII87_16375	COG1136	(ABC) transporter
GII87_16390	COG1131	(ABC) transporter
GII87_16395	COG1725	Transcriptional regulator
GII87_16410	COG1242	4 iron, 4 sulfur cluster binding
GII87_16415	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII87_16425	COG2267	carboxylic ester hydrolase activity
GII87_16430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII87_16435	COG1113	amino acid transport
GII87_16440	COG0367	asparagine synthase
GII87_16445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII87_16450	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII87_16460	COG1506	peptidase
GII87_16465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII87_16470	COG1116	anion transmembrane transporter activity
GII87_16475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII87_16480	COG0494	nUDIX hydrolase
GII87_16485	COG4824	toxin secretion phage lysis holin
GII87_16490	COG0783	Belongs to the Dps family
GII87_16505	COG1854	S-ribosylhomocysteine lyase activity
GII87_16510	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII87_16515	COG0288	reversible hydration of carbon dioxide
GII87_16520	COG0254	rRNA binding
GII87_16525	COG1271	oxidase subunit
GII87_16530	COG1294	oxidase, subunit
GII87_16540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII87_16545	COG1321	iron dependent repressor
GII87_16545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII87_16550	COG1121	(ABC) transporter
GII87_16555	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII87_16560	COG4948	Mandelate Racemase Muconate Lactonizing
GII87_16565	COG0318	PFAM AMP-dependent synthetase and ligase
GII87_16570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII87_16575	COG0596	Alpha beta hydrolase
GII87_16580	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII87_16585	COG1169	isochorismate synthase
GII87_16590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII87_16595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII87_16600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII87_16605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII87_16610	COG0438	transferase activity, transferring glycosyl groups
GII87_16620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII87_16625	COG0438	transferase activity, transferring glycosyl groups
GII87_16630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII87_16635	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GII87_16640	COG0058	SHG alpha-glucan phosphorylase activity
GII87_16645	COG0297	glycogen (starch) synthase activity
GII87_16650	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII87_16655	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII87_16660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII87_16785	COG3859	Proton-coupled thiamine transporter YuaJ
GII87_16790	COG1247	-acetyltransferase
GII87_16795	COG2268	Band 7 protein
GII87_16800	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII87_16805	COG2318	DinB family
GII87_16815	COG1454	alcohol dehydrogenase
GII87_16825	COG1510	regulation of RNA biosynthetic process
GII87_16835	COG0569	domain protein
GII87_16840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII87_16845	COG4682	membrane
GII87_16850	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII87_16855	COG0477	Major facilitator Superfamily
GII87_16860	COG5553	Cysteine dioxygenase type I
GII87_16870	COG1968	undecaprenyl-diphosphatase activity
GII87_16875	COG0628	permease
GII87_16880	COG0673	inositol 2-dehydrogenase activity
GII87_16885	COG4806	L-rhamnose isomerase
GII87_16890	COG3254	rhamnose metabolic process
GII87_16895	COG1070	Carbohydrate kinase
GII87_16900	COG1349	DNA-binding transcription factor activity
GII87_16905	COG3347	Dehydrogenase
GII87_16905	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_16910	COG0840	transmembrane signaling receptor activity
GII87_16915	COG0840	transmembrane signaling receptor activity
GII87_16920	COG0840	transmembrane signaling receptor activity
GII87_16925	COG0840	transmembrane signaling receptor activity
GII87_16940	COG0432	Pfam Uncharacterised protein family UPF0047
GII87_16950	COG0366	Alpha amylase catalytic
GII87_16955	COG1253	flavin adenine dinucleotide binding
GII87_16960	COG2738	Putative neutral zinc metallopeptidase
GII87_16975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII87_16990	COG0166	Belongs to the GPI family
GII87_16995	COG1979	alcohol dehydrogenase
GII87_17000	COG1979	alcohol dehydrogenase
GII87_17005	COG2155	Conserved Protein
GII87_17010	COG1098	S1 RNA binding domain
GII87_17015	COG0436	Aminotransferase
GII87_17020	COG1522	sequence-specific DNA binding
GII87_17025	COG2267	carboxylic ester hydrolase activity
GII87_17035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII87_17040	COG2205	protein histidine kinase activity
GII87_17050	COG5018	Exonuclease
GII87_17060	COG2814	Major facilitator Superfamily
GII87_17065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII87_17070	COG3011	Protein conserved in bacteria
GII87_17080	COG3290	protein histidine kinase activity
GII87_17085	COG4565	transcriptional regulatory protein
GII87_17110	COG3493	citrate carrier protein
GII87_17120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII87_17120	COG2111	Na H antiporter
GII87_17125	COG2111	Na H antiporter
GII87_17130	COG1006	Multisubunit Na H antiporter MnhC subunit
GII87_17135	COG0651	ATP synthesis coupled electron transport
GII87_17140	COG1863	multisubunit Na H antiporter MnhE subunit
GII87_17145	COG2212	antiporter activity
GII87_17150	COG1320	monovalent cation:proton antiporter activity
GII87_17155	COG2050	protein possibly involved in aromatic compounds catabolism
GII87_17160	COG2197	response regulator
GII87_17165	COG4585	Histidine kinase
GII87_17175	COG0142	geranyltranstransferase activity
GII87_17195	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII87_17200	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII87_17205	COG1335	isochorismatase
GII87_17210	COG5506	Protein of unknown function (DUF1694)
GII87_17225	COG0628	permease
GII87_17240	COG1418	mRNA catabolic process
GII87_17245	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_17255	COG1511	domain protein
GII87_17260	COG0433	COG0433 Predicted ATPase
GII87_17260	COG1674	ftsk spoiiie
GII87_17265	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII87_17270	COG5417	Belongs to the EsaB family
GII87_17275	COG4842	Belongs to the WXG100 family
GII87_17280	COG2508	Transcriptional regulator
GII87_17280	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII87_17285	COG0686	Belongs to the AlaDH PNT family
GII87_17290	COG5634	Uncharacterized conserved protein (DUF2278)
GII87_17295	COG3251	PFAM MbtH domain protein
GII87_17300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_17305	COG1535	isochorismatase
GII87_17305	COG3433	isochorismatase activity
GII87_17310	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII87_17315	COG1169	isochorismate synthase
GII87_17320	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_17325	COG2819	hydrolase of the alpha beta superfamily
GII87_17330	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII87_17335	COG1268	BioY protein
GII87_17340	COG2056	Na+-H+ antiporter family
GII87_17345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII87_17350	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII87_17355	COG3584	3D domain protein
GII87_17370	COG1252	NADH dehydrogenase
GII87_17375	COG0492	ferredoxin-NADP+ reductase activity
GII87_17385	COG0516	GMP reductase activity
GII87_17390	COG2808	Putative FMN-binding domain
GII87_17395	COG0456	acetyltransferase
GII87_17400	COG0316	Belongs to the HesB IscA family
GII87_17405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII87_17410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII87_17415	COG4844	belongs to the
GII87_17420	COG1252	NADH dehydrogenase
GII87_17425	COG4837	Protein of unknown function (DUF1462)
GII87_17430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII87_17435	COG0823	Involved in the tonB-independent uptake of proteins
GII87_17435	COG1506	peptidase
GII87_17435	COG4946	Tricorn protease homolog
GII87_17440	COG0083	homoserine kinase activity
GII87_17445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII87_17450	COG0460	homoserine dehydrogenase
GII87_17455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII87_17460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII87_17465	COG0647	UMP catabolic process
GII87_17470	COG2445	Protein of unknown function DUF86
GII87_17475	COG4470	Protein conserved in bacteria
GII87_17485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII87_17490	COG0739	heme binding
GII87_17500	COG3377	Domain of unknown function (DUF1805)
GII87_17505	COG0737	Belongs to the 5'-nucleotidase family
GII87_17510	COG0730	response to heat
GII87_17515	COG1801	Protein of unknown function DUF72
GII87_17525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII87_17530	COG2508	Transcriptional regulator
GII87_17535	COG2233	PERMEase
GII87_17540	COG2233	PERMEase
GII87_17545	COG3195	allantoin biosynthetic process
GII87_17545	COG3648	Uricase
GII87_17550	COG2351	hydroxyisourate hydrolase activity
GII87_17560	COG2080	2 iron, 2 sulfur cluster binding
GII87_17565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII87_17570	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII87_17575	COG2068	MobA-Related Protein
GII87_17580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII87_17585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII87_17590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII87_17600	COG2356	endonuclease I
GII87_17605	COG3842	ATPase activity
GII87_17610	COG2188	Transcriptional regulator
GII87_17615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII87_17620	COG0395	ABC-type sugar transport system, permease component
GII87_17625	COG1175	transmembrane transport
GII87_17630	COG1653	transport
GII87_17635	COG2222	sugar isomerase
GII87_17640	COG0322	excinuclease ABC activity
GII87_17645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII87_17660	COG0346	lactoylglutathione lyase activity
GII87_17665	COG0640	Transcriptional regulator
GII87_17670	COG0719	Fe-S assembly protein
GII87_17675	COG0822	iron-sulfur transferase activity
GII87_17680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII87_17685	COG0719	Fe-S assembly protein
GII87_17690	COG0396	ATPase activity
GII87_17700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII87_17705	COG1464	Belongs to the NlpA lipoprotein family
GII87_17710	COG2011	ABC-type metal ion transport system permease component
GII87_17715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII87_17725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII87_17730	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII87_17740	COG0509	glycine decarboxylation via glycine cleavage system
GII87_17745	COG1393	Belongs to the ArsC family
GII87_17750	COG1960	acyl-CoA dehydrogenase activity
GII87_17755	COG0183	Belongs to the thiolase family
GII87_17760	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII87_17760	COG1024	Enoyl-CoA hydratase
GII87_17770	COG0506	proline dehydrogenase activity
GII87_17780	COG5577	PFAM Coat F domain
GII87_17785	COG1846	Transcriptional regulator
GII87_17790	COG0477	Major facilitator Superfamily
GII87_17795	COG1942	4-Oxalocrotonate Tautomerase
GII87_17805	COG0583	DNA-binding transcription factor activity
GII87_17815	COG1120	ATPase activity
GII87_17830	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_17835	COG0783	Belongs to the Dps family
GII87_17840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII87_17845	COG0745	RESPONSE REGULATOR receiver
GII87_17850	COG2770	Histidine kinase
GII87_17850	COG2205	protein histidine kinase activity
GII87_17860	COG1309	transcriptional regulator
GII87_17865	COG0114	fumarate hydratase activity
GII87_17875	COG0697	spore germination
GII87_17880	COG0814	amino acid
GII87_17890	COG2197	response regulator
GII87_17895	COG4585	Histidine kinase
GII87_17900	COG4758	membrane
GII87_17905	COG3595	metallopeptidase activity
GII87_17910	COG1842	Phage shock protein A
GII87_17915	COG4758	membrane
GII87_17920	COG2814	Major facilitator Superfamily
GII87_17925	COG2096	Adenosyltransferase
GII87_17930	COG1120	ATPase activity
GII87_17935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII87_17940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII87_17945	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_17950	COG3386	PFAM SMP-30 Gluconolaconase
GII87_17955	COG2205	protein histidine kinase activity
GII87_17960	COG0745	RESPONSE REGULATOR receiver
GII87_17970	COG1191	sigma factor activity
GII87_17980	COG2140	Oxalate decarboxylase
GII87_17990	COG0577	efflux transmembrane transporter activity
GII87_17995	COG1136	(ABC) transporter
GII87_18000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII87_18005	COG1120	ATPase activity
GII87_18010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII87_18015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII87_18020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII87_18025	COG0531	amino acid
GII87_18035	COG1988	membrane-bound metal-dependent
GII87_18040	COG1368	sulfuric ester hydrolase activity
GII87_18045	COG1910	domain protein
GII87_18050	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII87_18055	COG4149	molybdate abc transporter
GII87_18060	COG0656	L-ascorbic acid biosynthetic process
GII87_18070	COG0025	NhaP-type Na H and K H
GII87_18075	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII87_18080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII87_18085	COG3973	AAA domain
GII87_18090	COG2860	membrane
GII87_18095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII87_18100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII87_18105	COG2217	Heavy metal translocating P-type atpase
GII87_18110	COG2217	Heavy metal translocating P-type atpase
GII87_18115	COG2608	mercury ion transmembrane transporter activity
GII87_18120	COG1937	Protein conserved in bacteria
GII87_18125	COG0673	inositol 2-dehydrogenase activity
GII87_18130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII87_18135	COG1289	transmembrane transporter activity
GII87_18145	COG2076	Multidrug Resistance protein
GII87_18150	COG1309	transcriptional regulator
GII87_18155	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_18165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII87_18170	COG0557	exoribonuclease II activity
GII87_18175	COG1647	Serine aminopeptidase, S33
GII87_18180	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII87_18185	COG0596	Alpha beta hydrolase
GII87_18190	COG1476	TRANSCRIPTIONal
GII87_18195	COG1396	sequence-specific DNA binding
GII87_18200	COG1396	sequence-specific DNA binding
GII87_18205	COG1733	regulation of RNA biosynthetic process
GII87_18210	COG0840	transmembrane signaling receptor activity
GII87_18215	COG1174	glycine betaine transport
GII87_18220	COG1732	Glycine betaine
GII87_18225	COG1174	glycine betaine transport
GII87_18230	COG1125	glycine betaine transport
GII87_18230	COG0517	IMP dehydrogenase activity
GII87_18235	COG1510	regulation of RNA biosynthetic process
GII87_18255	COG5658	integral membrane protein
GII87_18260	COG0640	Transcriptional regulator
GII87_18265	COG1174	glycine betaine transport
GII87_18270	COG1732	Glycine betaine
GII87_18275	COG1174	glycine betaine transport
GII87_18280	COG1125	glycine betaine transport
GII87_18280	COG0517	IMP dehydrogenase activity
GII87_18285	COG1510	regulation of RNA biosynthetic process
GII87_18290	COG2095	MarC family integral membrane protein
GII87_18300	COG3064	Membrane
GII87_18305	COG4640	response to antibiotic
GII87_18310	COG0456	acetyltransferase
GII87_18315	COG0148	phosphopyruvate hydratase activity
GII87_18320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII87_18325	COG0149	triose-phosphate isomerase activity
GII87_18330	COG0126	phosphoglycerate kinase activity
GII87_18335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII87_18340	COG2390	Transcriptional regulator
GII87_18345	COG2814	Major facilitator Superfamily
GII87_18350	COG1609	Transcriptional regulator
GII87_18355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII87_18360	COG0583	DNA-binding transcription factor activity
GII87_18365	COG0697	spore germination
GII87_18370	COG1113	amino acid transport
GII87_18375	COG3858	chitin binding
GII87_18380	COG1556	Lactate utilization protein
GII87_18385	COG1139	Iron-sulfur cluster binding protein
GII87_18390	COG0247	lactate metabolic process
GII87_18395	COG2197	response regulator
GII87_18400	COG4585	Histidine kinase
GII87_18405	COG0842	Transport permease protein
GII87_18410	COG1131	(ABC) transporter
GII87_18415	COG0596	Alpha beta hydrolase
GII87_18420	COG2208	phosphoserine phosphatase activity
GII87_18425	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII87_18430	COG1874	Beta-galactosidase
GII87_18435	COG3833	ABC-type maltose transport systems, permease component
GII87_18440	COG1175	transmembrane transport
GII87_18445	COG2182	Extracellular solute-binding protein
GII87_18450	COG1609	Transcriptional regulator
GII87_18455	COG2186	Transcriptional regulator
GII87_18460	COG1620	l-lactate permease
GII87_18465	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII87_18475	COG5039	Polysaccharide pyruvyl transferase
GII87_18480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII87_18485	COG0110	maltose O-acetyltransferase activity
GII87_18490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII87_18495	COG2244	polysaccharide biosynthetic process
GII87_18500	COG1216	Glycosyl transferase, family 2
GII87_18505	COG5039	Polysaccharide pyruvyl transferase
GII87_18510	COG1216	Glycosyl transferase, family 2
GII87_18520	COG0438	transferase activity, transferring glycosyl groups
GII87_18525	COG1215	transferase activity, transferring glycosyl groups
GII87_18530	COG0438	transferase activity, transferring glycosyl groups
GII87_18535	COG1086	Polysaccharide biosynthesis protein
GII87_18540	COG0489	protein tyrosine kinase activity
GII87_18545	COG3944	biosynthesis protein
GII87_18550	COG1396	sequence-specific DNA binding
GII87_18555	COG2272	Belongs to the type-B carboxylesterase lipase family
GII87_18565	COG3479	Phenolic acid decarboxylase
GII87_18575	COG1794	racemase activity, acting on amino acids and derivatives
GII87_18580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII87_18585	COG1621	beta-fructofuranosidase activity
GII87_18590	COG1621	beta-fructofuranosidase activity
GII87_18595	COG0531	amino acid
GII87_18600	COG1309	transcriptional regulator
GII87_18605	COG2076	Multidrug Resistance protein
GII87_18610	COG2076	Multidrug Resistance protein
GII87_18620	COG0277	FAD linked oxidase domain protein
GII87_18625	COG3621	Patatin-like phospholipase
GII87_18635	COG0740	serine-type endopeptidase activity
GII87_18640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII87_18645	COG0366	Alpha amylase catalytic
GII87_18650	COG1554	hydrolase, family 65, central catalytic
GII87_18655	COG5521	maltodextrose utilization protein MalA
GII87_18660	COG3833	ABC-type maltose transport systems, permease component
GII87_18665	COG1175	transmembrane transport
GII87_18670	COG2182	Extracellular solute-binding protein
GII87_18675	COG0366	Alpha amylase catalytic
GII87_18680	COG1609	Transcriptional regulator
GII87_18685	COG1611	Belongs to the LOG family
GII87_18690	COG1694	Mazg nucleotide pyrophosphohydrolase
GII87_18695	COG0659	secondary active sulfate transmembrane transporter activity
GII87_18700	COG0288	reversible hydration of carbon dioxide
GII87_18705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII87_18710	COG0577	efflux transmembrane transporter activity
GII87_18715	COG1136	(ABC) transporter
GII87_18720	COG5002	protein histidine kinase activity
GII87_18725	COG0745	RESPONSE REGULATOR receiver
GII87_18735	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII87_18740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII87_18745	COG1481	regulation of sporulation
GII87_18750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII87_18755	COG1660	Displays ATPase and GTPase activities
GII87_18760	COG1051	belongs to the nudix hydrolase family
GII87_18765	COG0492	ferredoxin-NADP+ reductase activity
GII87_18770	COG0791	NLP P60 protein
GII87_18770	COG3883	PFAM NLP P60 protein
GII87_18775	COG0457	Tetratricopeptide repeat
GII87_18780	COG1132	(ABC) transporter
GII87_18800	COG0140	phosphoribosyl-ATP diphosphatase activity
GII87_18800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII87_18805	COG0107	imidazoleglycerol-phosphate synthase activity
GII87_18810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII87_18815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII87_18820	COG0131	Imidazoleglycerol-phosphate dehydratase
GII87_18825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII87_18830	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII87_18835	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII87_18840	COG4990	cell redox homeostasis
GII87_18845	COG5297	Belongs to the glycosyl hydrolase family 6
GII87_18850	COG0110	maltose O-acetyltransferase activity
GII87_18855	COG0546	phosphoglycolate phosphatase activity
GII87_18860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII87_18865	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII87_18870	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII87_18875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII87_18880	COG0363	glucosamine-6-phosphate deaminase activity
GII87_18890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII87_18895	COG1846	Transcriptional regulator
GII87_18900	COG2124	cytochrome p450
GII87_18910	COG1846	Transcriptional regulator
GII87_18915	COG2814	Major facilitator Superfamily
GII87_18920	COG1950	PFAM Membrane protein of
GII87_18925	COG1983	PspC domain protein
GII87_18930	COG3595	metallopeptidase activity
GII87_18950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII87_18955	COG0556	nucleotide-excision repair
GII87_18960	COG4897	Protein conserved in bacteria
GII87_18965	COG3848	Pyruvate phosphate dikinase
GII87_18965	COG0574	Belongs to the PEP-utilizing enzyme family
GII87_18970	COG1309	transcriptional regulator
GII87_18975	COG2814	Major facilitator Superfamily
GII87_18980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII87_18990	COG3409	Peptidoglycan-binding domain 1 protein
GII87_18990	COG0793	Belongs to the peptidase S41A family
GII87_18995	COG2177	Part of the ABC transporter FtsEX involved in
GII87_19000	COG2884	Cell division ATP-binding protein ftsE
GII87_19005	COG2010	Cytochrome c
GII87_19010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII87_19020	COG0653	protein targeting
GII87_19025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII87_19040	COG1516	flagellar protein fliS
GII87_19045	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII87_19050	COG1334	flagellar protein FlaG
GII87_19055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII87_19060	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII87_19065	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII87_19075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII87_19080	COG4786	Flagellar basal body rod
GII87_19080	COG1256	bacterial-type flagellum assembly
GII87_19085	COG3418	PFAM FlgN family protein
GII87_19090	COG2747	anti-sigma28 factor FlgM
GII87_19100	COG1040	competence protein
GII87_19110	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII87_19115	COG1307	EDD domain protein, DegV family
GII87_19120	COG2197	response regulator
GII87_19125	COG4585	Histidine kinase
GII87_19130	COG1739	Uncharacterized protein family UPF0029
GII87_19135	COG1316	TRANSCRIPTIONal
GII87_19140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII87_19145	COG0438	transferase activity, transferring glycosyl groups
GII87_19150	COG1215	transferase activity, transferring glycosyl groups
GII87_19155	COG3206	protein involved in exopolysaccharide biosynthesis
GII87_19160	COG3307	-O-antigen
GII87_19165	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII87_19170	COG0297	glycogen (starch) synthase activity
GII87_19170	COG0438	transferase activity, transferring glycosyl groups
GII87_19175	COG2244	polysaccharide biosynthetic process
GII87_19185	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII87_19185	COG2247	cell wall binding repeat
GII87_19190	COG2385	sporulation resulting in formation of a cellular spore
GII87_19190	COG2247	cell wall binding repeat
GII87_19200	COG1316	TRANSCRIPTIONal
GII87_19205	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII87_19210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII87_19220	COG1215	transferase activity, transferring glycosyl groups
GII87_19220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII87_19225	COG0463	Glycosyl transferase, family 2
GII87_19235	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII87_19245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII87_19250	COG1134	teichoic acid transport
GII87_19255	COG1682	transport, permease protein
GII87_19260	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII87_19265	COG0438	transferase activity, transferring glycosyl groups
GII87_19270	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GII87_19275	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GII87_19280	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII87_19290	COG4193	domain, Protein
GII87_19295	COG1482	cell wall glycoprotein biosynthetic process
GII87_19300	COG0697	spore germination
GII87_19305	COG0814	amino acid
GII87_19315	COG2814	Major facilitator Superfamily
GII87_19320	COG1316	TRANSCRIPTIONal
GII87_19325	COG0561	phosphatase activity
GII87_19330	COG0791	NLP P60 protein
GII87_19340	COG2843	Capsule synthesis protein
GII87_19350	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII87_19355	COG1609	Transcriptional regulator
GII87_19360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII87_19365	COG1869	D-ribose catabolic process
GII87_19370	COG1129	ABC transporter
GII87_19375	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII87_19380	COG1879	ABC-type sugar transport system periplasmic component
GII87_19385	COG3103	Sh3 type 3 domain protein
GII87_19395	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII87_19400	COG3527	Alpha-acetolactate decarboxylase
GII87_19405	COG0028	Belongs to the TPP enzyme family
GII87_19410	COG0583	DNA-binding transcription factor activity
GII87_19415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII87_19430	COG5337	Spore coat protein CotH
GII87_19440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII87_19450	COG0405	Gamma-glutamyltransferase
GII87_19455	COG1522	sequence-specific DNA binding
GII87_19460	COG2059	Chromate
GII87_19465	COG2059	Chromate
GII87_19475	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII87_19480	COG0583	DNA-binding transcription factor activity
GII87_19485	COG1515	deoxyribonuclease V activity
GII87_19490	COG2849	repeat protein
GII87_19495	COG5444	nuclease activity
GII87_19515	COG3878	Protein conserved in bacteria
GII87_19520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII87_19525	COG4464	protein tyrosine phosphatase activity
GII87_19530	COG0489	protein tyrosine kinase activity
GII87_19535	COG3944	biosynthesis protein
GII87_19545	COG4715	Zinc finger, swim domain protein
GII87_19550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII87_19555	COG0561	phosphatase activity
GII87_19560	COG1349	DNA-binding transcription factor activity
GII87_19565	COG0629	single-stranded DNA binding
GII87_19580	COG3764	Sortase (surface protein transpeptidase)
GII87_19590	COG0745	RESPONSE REGULATOR receiver
GII87_19590	COG2972	Histidine kinase
GII87_19595	COG1970	mechanosensitive ion channel activity
GII87_19600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII87_19605	COG0457	Tetratricopeptide repeat
GII87_19610	COG4786	Flagellar basal body rod
GII87_19615	COG4786	Flagellar basal body rod
GII87_19620	COG1077	Cell shape determining protein MreB Mrl
GII87_19625	COG1609	Transcriptional regulator
GII87_19635	COG1846	Transcriptional regulator
GII87_19640	COG2814	Major facilitator Superfamily
GII87_19645	COG3420	alginic acid biosynthetic process
GII87_19650	COG1953	Uracil, thiamine, allantoin
GII87_19655	COG0477	Major facilitator Superfamily
GII87_19660	COG1335	isochorismatase
GII87_19670	COG0004	ammonium transporteR
GII87_19675	COG0347	Belongs to the P(II) protein family
GII87_19680	COG0671	phosphoesterase, PA-phosphatase related
GII87_19690	COG0739	heme binding
GII87_19695	COG1247	-acetyltransferase
GII87_19715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII87_19720	COG0789	Transcriptional regulator
GII87_19730	COG2910	NAD(P)H-binding
GII87_19735	COG1959	2 iron, 2 sulfur cluster binding
GII87_19740	COG0804	urea catabolic process
GII87_19745	COG0832	Belongs to the urease beta subunit family
GII87_19750	COG0831	urea catabolic process
GII87_19765	COG3237	CsbD-like
GII87_19770	COG1994	Peptidase M50
GII87_19775	COG0457	Tetratricopeptide repeat
GII87_19780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII87_19785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII87_19795	COG2304	oxidoreductase activity
GII87_19805	COG2304	oxidoreductase activity
GII87_19810	COG2385	sporulation resulting in formation of a cellular spore
GII87_19815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII87_19825	COG4836	Membrane
GII87_19835	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII87_19840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII87_19845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII87_19850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII87_19855	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII87_19860	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII87_19865	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII87_19870	COG0356	it plays a direct role in the translocation of protons across the membrane
GII87_19880	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII87_19885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII87_19890	COG4475	Protein of unknown function (DUF436)
GII87_19895	COG0698	ribose 5-phosphate isomerase
GII87_19900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII87_19905	COG1971	Probably functions as a manganese efflux pump
GII87_19910	COG0009	L-threonylcarbamoyladenylate synthase
GII87_19915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII87_19935	COG2890	protein-(glutamine-N5) methyltransferase activity
GII87_19940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII87_19945	COG0346	lactoylglutathione lyase activity
GII87_19950	COG0789	Transcriptional regulator
GII87_19955	COG0679	Auxin Efflux Carrier
GII87_19960	COG0281	malic enzyme
GII87_19965	COG1435	thymidine kinase activity
GII87_19970	COG0254	rRNA binding
GII87_19975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII87_19985	COG1494	fructose-1,6-bisphosphatase
GII87_19990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII87_19995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII87_20000	COG0191	fructose-bisphosphate aldolase activity
GII87_20005	COG2204	response regulator
GII87_20010	COG4821	SIS domain
GII87_20015	COG0504	CTP synthase activity
GII87_20020	COG3343	RNA polymerase activity
GII87_20025	COG1960	acyl-CoA dehydrogenase activity
GII87_20030	COG2181	nitrate reductase activity
GII87_20030	COG0247	lactate metabolic process
GII87_20035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII87_20040	COG4294	response to UV
GII87_20050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII87_20055	COG1132	(ABC) transporter
GII87_20060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII87_20070	COG2181	nitrate reductase activity
GII87_20075	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GII87_20080	COG1140	nitrate reductase beta subunit
GII87_20085	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII87_20090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII87_20100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII87_20105	COG2223	nitrite transmembrane transporter activity
GII87_20110	COG0018	arginyl-trna synthetase
GII87_20115	COG4506	Protein conserved in bacteria
GII87_20130	COG0535	radical SAM domain protein
GII87_20140	COG1131	(ABC) transporter
GII87_20145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII87_20150	COG0612	Peptidase, M16
GII87_20155	COG0612	Peptidase, M16
GII87_20165	COG3391	amine dehydrogenase activity
GII87_20170	COG3391	amine dehydrogenase activity
GII87_20180	COG0457	Tetratricopeptide repeat
GII87_20190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII87_20195	COG0010	Belongs to the arginase family
GII87_20200	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII87_20205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII87_20215	COG1994	Peptidase M50
GII87_20220	COG1942	4-Oxalocrotonate Tautomerase
GII87_20225	COG1846	Transcriptional regulator
GII87_20230	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII87_20235	COG0477	Major facilitator Superfamily
GII87_20240	COG1959	2 iron, 2 sulfur cluster binding
GII87_20245	COG3465	dGTPase activity
GII87_20250	COG1078	dGTPase activity
GII87_20255	COG4844	belongs to the
GII87_20265	COG0697	spore germination
GII87_20270	COG0095	Lipoate-protein ligase
GII87_20275	COG0583	DNA-binding transcription factor activity
GII87_20280	COG0280	phosphate acetyltransferase
GII87_20290	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_20295	COG0436	Aminotransferase
GII87_20300	COG2814	Major facilitator Superfamily
GII87_20305	COG0151	Belongs to the GarS family
GII87_20310	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_20315	COG1917	Cupin 2, conserved barrel domain protein
GII87_20320	COG0077	Prephenate dehydratase
GII87_20325	COG2814	Major facilitator Superfamily
GII87_20330	COG0833	amino acid
GII87_20335	COG4187	Peptidase family M20/M25/M40
GII87_20340	COG1012	belongs to the aldehyde dehydrogenase family
GII87_20345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII87_20355	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII87_20360	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII87_20365	COG1088	dTDP-glucose 4,6-dehydratase activity
GII87_20370	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII87_20375	COG3980	spore coat polysaccharide biosynthesis protein
GII87_20380	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII87_20385	COG2089	acid synthase
GII87_20390	COG0456	acetyltransferase
GII87_20395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII87_20400	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII87_20405	COG0463	Glycosyl transferase, family 2
GII87_20415	COG2363	Small membrane protein
GII87_20420	COG2233	PERMEase
GII87_20430	COG1012	belongs to the aldehyde dehydrogenase family
GII87_20435	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII87_20440	COG1216	Glycosyl transferase, family 2
GII87_20455	COG1695	Transcriptional regulator
GII87_20460	COG0351	phosphomethylpyrimidine kinase
GII87_20470	COG1621	beta-fructofuranosidase activity
GII87_20475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_20475	COG1263	PTS System
GII87_20480	COG2116	formate transmembrane transporter activity
GII87_20485	COG3711	transcriptional antiterminator
GII87_20495	COG1404	Belongs to the peptidase S8 family
GII87_20500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII87_20505	COG0778	Nitroreductase
GII87_20510	COG0772	Belongs to the SEDS family
GII87_20520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII87_20525	COG1845	cytochrome c oxidase, subunit III
GII87_20530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII87_20535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII87_20540	COG2261	transglycosylase associated protein
GII87_20545	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII87_20550	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII87_20555	COG2246	polysaccharide biosynthetic process
GII87_20560	COG1309	transcriptional regulator
GII87_20570	COG3162	membrane
GII87_20575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII87_20580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII87_20585	COG2837	iron assimilation
GII87_20590	COG2822	iron ion transport
GII87_20595	COG0672	)-iron permease
GII87_20600	COG0352	thiamine-phosphate diphosphorylase activity
GII87_20605	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII87_20610	COG0583	DNA-binding transcription factor activity
GII87_20615	COG1380	Effector of murein hydrolase LrgA
GII87_20620	COG1346	cytolysis
GII87_20625	COG2814	Major facilitator Superfamily
GII87_20630	COG4895	conserved protein (DUF2196)
GII87_20635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII87_20640	COG0346	lactoylglutathione lyase activity
GII87_20650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII87_20655	COG1404	Belongs to the peptidase S8 family
GII87_20660	COG1263	PTS System
GII87_20660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_20665	COG3711	transcriptional antiterminator
GII87_20670	COG1442	glycosyl transferase family 8
GII87_20675	COG5522	Integral membrane protein (intg_mem_TP0381)
GII87_20680	COG1846	Transcriptional regulator
GII87_20685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII87_20690	COG2234	aminopeptidase activity
GII87_20695	COG2357	RelA SpoT domain protein
GII87_20700	COG1575	Belongs to the MenA family. Type 1 subfamily
GII87_20715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII87_20720	COG1696	Membrane protein involved in D-alanine export
GII87_20725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII87_20730	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII87_20735	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII87_20740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII87_20745	COG1486	melibiose metabolic process
GII87_20750	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII87_20755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII87_20760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII87_20765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII87_20765	COG3711	transcriptional antiterminator
GII87_20775	COG2094	Belongs to the DNA glycosylase MPG family
GII87_20780	COG0753	catalase activity
GII87_20785	COG2814	Major facilitator Superfamily
GII87_20790	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII87_20795	COG1131	(ABC) transporter
GII87_20815	COG1595	DNA-templated transcription, initiation
GII87_20820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII87_20825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII87_20830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII87_20835	COG4988	ABC transporter
GII87_20840	COG1294	oxidase, subunit
GII87_20845	COG1271	oxidase subunit
GII87_20850	COG3493	citrate carrier protein
GII87_20855	COG0501	Belongs to the peptidase M48B family
GII87_20865	COG0726	polysaccharide deacetylase
GII87_20870	COG3842	ATPase activity
GII87_20875	COG2508	Transcriptional regulator
GII87_20880	COG1012	belongs to the aldehyde dehydrogenase family
GII87_20885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII87_20895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII87_20900	COG1881	PFAM PEBP family protein
GII87_20905	COG0583	DNA-binding transcription factor activity
GII87_20915	COG4585	Histidine kinase
GII87_20920	COG2197	response regulator
GII87_20925	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII87_20935	COG4894	glucomannan catabolic process
GII87_20940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII87_20945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII87_20950	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_20955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII87_20960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII87_20965	COG2610	gluconate transmembrane transporter activity
GII87_20970	COG0500	methyltransferase
GII87_20975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII87_20990	COG0693	protein deglycase activity
GII87_20990	COG0753	catalase activity
GII87_20995	COG2851	Citrate transporter
GII87_21000	COG2273	Hydrolase Family 16
GII87_21005	COG3711	transcriptional antiterminator
GII87_21015	COG2270	Major facilitator Superfamily
GII87_21020	COG0513	Belongs to the DEAD box helicase family
GII87_21025	COG2755	lipolytic protein G-D-S-L family
GII87_21025	COG3401	FG-GAP repeat protein
GII87_21085	COG3209	COG3209 Rhs family protein
GII87_21090	COG0697	spore germination
GII87_21095	COG0589	response to stress
GII87_21100	COG2723	6-phospho-beta-galactosidase activity
GII87_21105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_21105	COG1263	PTS System
GII87_21105	COG2190	(PTS) system
GII87_21120	COG5444	nuclease activity
GII87_21135	COG3507	Belongs to the glycosyl hydrolase 43 family
GII87_21150	COG2986	histidine ammonia-lyase
GII87_21155	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII87_21160	COG1228	amidohydrolase
GII87_21165	COG0010	Belongs to the arginase family
GII87_21170	COG0833	amino acid
GII87_21175	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII87_21180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII87_21185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII87_21190	COG2390	Transcriptional regulator
GII87_21200	COG3192	ethanolamine utilization protein
GII87_21205	COG2079	MmgE PrpD family protein
GII87_21215	COG1126	abc transporter atp-binding protein
GII87_21220	COG0765	amino acid transport
GII87_21225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII87_21245	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII87_21250	COG0561	phosphatase activity
GII87_21280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII87_21285	COG5294	Protein conserved in bacteria
GII87_21290	COG0577	efflux transmembrane transporter activity
GII87_21295	COG1136	(ABC) transporter
GII87_21300	COG2205	protein histidine kinase activity
GII87_21305	COG0745	RESPONSE REGULATOR receiver
GII87_21310	COG0191	fructose-bisphosphate aldolase activity
GII87_21315	COG1082	Xylose isomerase domain protein TIM barrel
GII87_21320	COG1082	Xylose isomerase domain protein TIM barrel
GII87_21325	COG0673	inositol 2-dehydrogenase activity
GII87_21330	COG2814	Major facilitator Superfamily
GII87_21335	COG1082	Xylose isomerase domain protein TIM barrel
GII87_21340	COG3962	Belongs to the TPP enzyme family
GII87_21345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII87_21350	COG3718	enzyme involved in inositol metabolism
GII87_21355	COG1012	belongs to the aldehyde dehydrogenase family
GII87_21360	COG1349	DNA-binding transcription factor activity
GII87_21365	COG0667	Aldo Keto reductase
GII87_21380	COG2814	Major facilitator Superfamily
GII87_21385	COG0326	Molecular chaperone. Has ATPase activity
GII87_21395	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_21400	COG1309	transcriptional regulator
GII87_21405	COG1012	belongs to the aldehyde dehydrogenase family
GII87_21410	COG0456	acetyltransferase
GII87_21415	COG2850	peptidyl-arginine hydroxylation
GII87_21420	COG2226	methyltransferase
GII87_21435	COG0367	asparagine synthase
GII87_21440	COG2814	Major facilitator Superfamily
GII87_21445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GII87_21455	COG1714	RDD family
GII87_21460	COG2311	Membrane
GII87_21465	COG1917	Cupin 2, conserved barrel domain protein
GII87_21470	COG1309	transcriptional regulator
GII87_21475	COG1028	Short-chain dehydrogenase reductase Sdr
GII87_21480	COG1846	Transcriptional regulator
GII87_21485	COG1380	Effector of murein hydrolase LrgA
GII87_21490	COG1346	cytolysis
GII87_21495	COG5039	Polysaccharide pyruvyl transferase
GII87_21500	COG1929	Belongs to the glycerate kinase type-1 family
GII87_21505	COG1802	Transcriptional regulator
GII87_21510	COG1070	Carbohydrate kinase
GII87_21515	COG2610	gluconate transmembrane transporter activity
GII87_21520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII87_21525	COG0450	alkyl hydroperoxide reductase
GII87_21530	COG3634	alkyl hydroperoxide reductase activity
GII87_21535	COG2723	6-phospho-beta-galactosidase activity
GII87_21540	COG2190	(PTS) system
GII87_21545	COG2190	(PTS) system
GII87_21545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII87_21545	COG1263	PTS System
GII87_21550	COG2188	Transcriptional regulator
GII87_21565	COG1131	(ABC) transporter
GII87_21570	COG1994	Peptidase M50
GII87_21575	COG0535	radical SAM domain protein
GII87_21585	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII87_21590	COG5293	efflux transmembrane transporter activity
GII87_21600	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII87_21605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII87_21620	COG1063	alcohol dehydrogenase
GII87_21640	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII87_21645	COG0456	acetyltransferase
GII87_21650	COG0457	Tetratricopeptide repeat
GII87_21660	COG0010	Belongs to the arginase family
GII87_21665	COG0833	amino acid
GII87_21670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII87_21675	COG3829	transcription factor binding
GII87_21690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII87_21695	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII87_21700	COG4853	Protein conserved in bacteria
GII87_21705	COG4863	YycH protein
GII87_21710	COG5002	protein histidine kinase activity
GII87_21715	COG0745	RESPONSE REGULATOR receiver
GII87_21745	COG0346	lactoylglutathione lyase activity
GII87_21750	COG0305	Participates in initiation and elongation during chromosome replication
GII87_21765	COG3093	addiction module antidote protein HigA
GII87_21770	COG2807	transmembrane transport
GII87_21775	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII87_21780	COG0359	binds to the 23S rRNA
GII87_21785	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII87_21790	COG4241	membrane
GII87_21800	COG5577	PFAM Coat F domain
GII87_21805	COG1733	regulation of RNA biosynthetic process
GII87_21810	COG1227	inorganic diphosphatase activity
GII87_21825	COG2271	Major facilitator Superfamily
GII87_21860	COG1131	(ABC) transporter
GII87_21875	COG4319	ketosteroid isomerase
GII87_21880	COG1357	PFAM Pentapeptide repeats (8 copies)
GII87_21885	COG2814	Major facilitator Superfamily
GII87_21890	COG0583	DNA-binding transcription factor activity
GII87_21895	COG2153	protein acetylation
GII87_21905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII87_21910	COG1846	Transcriptional regulator
GII87_21915	COG2153	protein acetylation
GII87_21920	COG2364	Membrane
GII87_21925	COG0456	acetyltransferase
GII87_21930	COG2315	Protein conserved in bacteria
GII87_21935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII87_21945	COG2814	Major facilitator Superfamily
GII87_21955	COG1331	Highly conserved protein containing a thioredoxin domain
GII87_21960	COG0789	Transcriptional regulator
GII87_21965	COG0697	spore germination
GII87_21970	COG1331	Highly conserved protein containing a thioredoxin domain
GII87_21975	COG1266	CAAX protease self-immunity
GII87_21980	COG2814	Major facilitator Superfamily
GII87_21980	COG0477	Major facilitator Superfamily
GII87_21985	COG0110	maltose O-acetyltransferase activity
GII87_21990	COG0346	lactoylglutathione lyase activity
GII87_21995	COG1609	Transcriptional regulator
GII87_22000	COG0708	Exodeoxyribonuclease III
GII87_22005	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII87_22010	COG0629	single-stranded DNA binding
GII87_22015	COG0360	Binds together with S18 to 16S ribosomal RNA
GII87_22020	COG0012	GTP binding
GII87_22025	COG0243	molybdopterin cofactor binding
GII87_22030	COG4481	Protein conserved in bacteria
GII87_22035	COG3949	Membrane
GII87_22045	COG1475	DNA binding
GII87_22050	COG1192	Involved in chromosome partitioning
GII87_22060	COG1475	DNA binding
GII87_22065	COG0357	Ribosomal RNA small subunit methyltransferase G
GII87_22070	COG0445	tRNA wobble uridine modification
GII87_22075	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII87_22080	COG1847	R3H domain protein
GII87_22085	COG0706	membrane insertase activity
GII87_22090	COG0594	ribonuclease P activity
GII87_22095	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GII87_22100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII87_22155	COG5444	nuclease activity
GII87_22210	COG3953	SLT domain
GII87_22210	COG5280	Phage tail tape measure protein TP901
GII87_22300	COG0457	Tetratricopeptide repeat
GII87_22320	COG3584	3D domain protein
GII87_22320	COG1388	LysM domain
GII87_22330	COG0582	viral genome integration into host DNA
GII87_22400	COG2887	Belongs to the helicase family. UvrD subfamily
GII87_22405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII87_22410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII87_22415	COG0716	FMN binding
GII87_22455	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII87_22490	COG0328	RNA-DNA hybrid ribonuclease activity
GII87_22510	COG0587	DNA-directed DNA polymerase activity
GII87_22530	COG0194	GDP metabolic process
GII87_22580	COG0187	DNA topoisomerase II activity