locus-tag	class	description
GII90_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII90_00010	COG0592	DNA-directed DNA polymerase activity
GII90_00015	COG2501	S4 domain
GII90_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII90_00030	COG0187	DNA topoisomerase II activity
GII90_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII90_00070	COG0516	GMP reductase activity
GII90_00070	COG0517	IMP dehydrogenase activity
GII90_00075	COG1686	Belongs to the peptidase S11 family
GII90_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII90_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII90_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII90_00100	COG1428	Deoxynucleoside kinase
GII90_00105	COG1428	Deoxynucleoside kinase
GII90_00110	COG3858	chitin binding
GII90_00110	COG1388	LysM domain
GII90_00115	COG1335	isochorismatase
GII90_00120	COG0590	tRNA wobble adenosine to inosine editing
GII90_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII90_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII90_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII90_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII90_00190	COG3853	Toxic anion resistance protein (TelA)
GII90_00195	COG1982	Orn Lys Arg decarboxylase major
GII90_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII90_00205	COG3870	Protein conserved in bacteria
GII90_00210	COG1728	Protein conserved in bacteria
GII90_00215	COG0470	DNA polymerase III
GII90_00220	COG1774	PSP1 C-terminal conserved region
GII90_00225	COG4467	Involved in initiation control of chromosome replication
GII90_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII90_00235	COG2827	Endonuclease containing a URI domain
GII90_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII90_00245	COG2002	toxin-antitoxin pair type II binding
GII90_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII90_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII90_00255	COG0084	hydrolase, TatD family'
GII90_00260	COG3584	3D domain protein
GII90_00260	COG3583	domain protein
GII90_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII90_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII90_00280	COG4466	Protein conserved in bacteria
GII90_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII90_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII90_00300	COG0251	oxidation-reduction process
GII90_00305	COG2088	sporulation resulting in formation of a cellular spore
GII90_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII90_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII90_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII90_00325	COG0193	aminoacyl-tRNA hydrolase activity
GII90_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII90_00340	COG2002	toxin-antitoxin pair type II binding
GII90_00345	COG2244	polysaccharide biosynthetic process
GII90_00350	COG3956	TIGRFAM MazG family protein
GII90_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII90_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII90_00375	COG1098	S1 RNA binding domain
GII90_00390	COG2208	phosphoserine phosphatase activity
GII90_00395	COG2304	oxidoreductase activity
GII90_00400	COG0515	serine threonine protein kinase
GII90_00405	COG0037	tRNA processing
GII90_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII90_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII90_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII90_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII90_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII90_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII90_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII90_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII90_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII90_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII90_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII90_00470	COG1396	sequence-specific DNA binding
GII90_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII90_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII90_00560	COG4463	regulation of RNA biosynthetic process
GII90_00565	COG3880	PFAM UvrB UvrC protein
GII90_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII90_00575	COG0542	response to heat
GII90_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII90_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII90_00590	COG4956	integral membrane protein (PIN domain superfamily)
GII90_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII90_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII90_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII90_00610	COG1045	serine acetyltransferase
GII90_00615	COG0215	cysteine-tRNA ligase activity
GII90_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII90_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII90_00630	COG3688	RNA-binding protein containing a PIN domain
GII90_00635	COG1595	DNA-templated transcription, initiation
GII90_00640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII90_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII90_00650	COG0250	Participates in transcription elongation, termination and antitermination
GII90_00655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GII90_00660	COG0081	regulation of translation
GII90_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII90_00670	COG0222	ribosome binding
GII90_00675	COG2813	Specifically methylates the guanine in position
GII90_00680	COG0085	RNA polymerase activity
GII90_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII90_00690	COG1358	cellular component organization or biogenesis
GII90_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII90_00700	COG0049	tRNA binding
GII90_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII90_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII90_00715	COG0596	Alpha beta hydrolase
GII90_00720	COG0051	transcription antitermination factor activity, RNA binding
GII90_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII90_00730	COG0088	Forms part of the polypeptide exit tunnel
GII90_00735	COG0089	rRNA binding
GII90_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII90_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GII90_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GII90_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GII90_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII90_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
GII90_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII90_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII90_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII90_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII90_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII90_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII90_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII90_00815	COG1841	ribosomal large subunit assembly
GII90_00820	COG0200	Binds to the 23S rRNA
GII90_00825	COG0201	protein transport
GII90_00830	COG0563	adenylate kinase activity
GII90_00835	COG0024	Methionine aminopeptidase
GII90_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII90_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GII90_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII90_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII90_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII90_00865	COG0202	RNA polymerase activity
GII90_00870	COG0203	ribosomal protein L17
GII90_00875	COG1122	ATPase activity
GII90_00880	COG1122	ATPase activity
GII90_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII90_00890	COG0101	tRNA pseudouridine synthase activity
GII90_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII90_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII90_00905	COG2226	methyltransferase
GII90_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII90_00920	COG0489	protein tyrosine kinase activity
GII90_00930	COG2194	sulfuric ester hydrolase activity
GII90_00935	COG0726	polysaccharide deacetylase
GII90_01020	COG0659	secondary active sulfate transmembrane transporter activity
GII90_01025	COG0385	Bile acid
GII90_01030	COG2819	hydrolase of the alpha beta superfamily
GII90_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII90_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII90_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII90_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII90_01050	COG2207	Transcriptional regulator
GII90_01055	COG3876	Protein conserved in bacteria
GII90_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
GII90_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII90_01070	COG1263	PTS System
GII90_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_01075	COG1737	Transcriptional regulator
GII90_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII90_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII90_01090	COG1683	Conserved Protein
GII90_01120	COG1595	DNA-templated transcription, initiation
GII90_01125	COG5662	AntiSigma factor
GII90_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII90_01135	COG4856	YbbR-like protein
GII90_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII90_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII90_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII90_01160	COG2169	Transcriptional regulator
GII90_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII90_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII90_01175	COG3002	Belongs to the UPF0753 family
GII90_01180	COG0288	reversible hydration of carbon dioxide
GII90_01190	COG5609	conserved protein (DUF2294)
GII90_01195	COG0640	Transcriptional regulator
GII90_01200	COG2814	Major facilitator Superfamily
GII90_01205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII90_01215	COG0535	radical SAM domain protein
GII90_01220	COG1266	CAAX protease self-immunity
GII90_01225	COG1131	(ABC) transporter
GII90_01235	COG1413	lyase activity
GII90_01240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII90_01245	COG0596	Alpha beta hydrolase
GII90_01250	COG0745	RESPONSE REGULATOR receiver
GII90_01255	COG0642	Histidine kinase
GII90_01265	COG0515	serine threonine protein kinase
GII90_01280	COG1113	amino acid transport
GII90_01295	COG2602	Beta-lactamase
GII90_01300	COG2124	cytochrome p450
GII90_01310	COG0531	amino acid
GII90_01315	COG0584	glycerophosphoryl diester phosphodiesterase
GII90_01320	COG2271	Major facilitator Superfamily
GII90_01330	COG1846	Transcriptional regulator
GII90_01330	COG0456	acetyltransferase
GII90_01335	COG2271	Major facilitator Superfamily
GII90_01345	COG3409	Peptidoglycan-binding domain 1 protein
GII90_01350	COG0697	spore germination
GII90_01355	COG2207	Transcriptional regulator
GII90_01355	COG1917	Cupin 2, conserved barrel domain protein
GII90_01360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII90_01365	COG3591	Belongs to the peptidase S1B family
GII90_01375	COG0596	Alpha beta hydrolase
GII90_01380	COG1183	phosphatidylcholine synthase activity
GII90_01385	COG0586	Pfam SNARE associated Golgi protein
GII90_01390	COG0688	phosphatidylethanolamine metabolic process
GII90_01400	COG2312	Erythromycin esterase
GII90_01405	COG2207	Transcriptional regulator
GII90_01415	COG1301	dicarboxylic acid transport
GII90_01420	COG2190	(PTS) system
GII90_01420	COG1263	PTS System
GII90_01420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_01425	COG0363	glucosamine-6-phosphate deaminase activity
GII90_01440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII90_01445	COG0833	amino acid
GII90_01450	COG2040	homocysteine
GII90_01460	COG1115	amino acid carrier protein
GII90_01465	COG2066	Belongs to the glutaminase family
GII90_01470	COG4191	Histidine kinase
GII90_01475	COG0784	Response regulator, receiver
GII90_01480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII90_01485	COG1012	belongs to the aldehyde dehydrogenase family
GII90_01490	COG2271	Major facilitator Superfamily
GII90_01495	COG4948	Mandelate Racemase Muconate Lactonizing
GII90_01500	COG2186	Transcriptional regulator
GII90_01505	COG2721	sulfolactate sulfo-lyase activity
GII90_01510	COG3173	Aminoglycoside phosphotransferase
GII90_01520	COG0697	spore germination
GII90_01525	COG0745	RESPONSE REGULATOR receiver
GII90_01530	COG2205	protein histidine kinase activity
GII90_01535	COG1131	(ABC) transporter
GII90_01555	COG3773	Cell wall hydrolase
GII90_01560	COG2304	oxidoreductase activity
GII90_01570	COG3540	Alkaline phosphatase
GII90_01575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII90_01580	COG0805	protein transport
GII90_01585	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII90_01590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII90_01595	COG0477	Major facilitator Superfamily
GII90_01600	COG1309	transcriptional regulator
GII90_01605	COG0252	asparaginase activity
GII90_01610	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII90_01615	COG1714	RDD family
GII90_01620	COG1405	negative regulation of cell septum assembly
GII90_01620	COG3012	SEC-C Motif Domain Protein
GII90_01625	COG3290	protein histidine kinase activity
GII90_01630	COG3279	Response regulator of the LytR AlgR family
GII90_01635	COG4555	ABC transporter
GII90_01640	COG1668	transmembrane transport
GII90_01645	COG0667	Aldo Keto reductase
GII90_01660	COG1595	DNA-templated transcription, initiation
GII90_01665	COG1595	DNA-templated transcription, initiation
GII90_01670	COG1876	peptidase activity
GII90_01675	COG0457	Tetratricopeptide repeat
GII90_01680	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_01685	COG0366	Alpha amylase catalytic
GII90_01690	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII90_01695	COG1121	(ABC) transporter
GII90_01700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII90_01705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII90_01710	COG2310	stress, protein
GII90_01715	COG2310	stress, protein
GII90_01720	COG2310	stress, protein
GII90_01725	COG0861	Integral membrane protein TerC family
GII90_01735	COG3853	Toxic anion resistance protein (TelA)
GII90_01740	COG0477	Major facilitator Superfamily
GII90_01745	COG2814	Major facilitator Superfamily
GII90_01750	COG0640	Transcriptional regulator
GII90_01755	COG0517	IMP dehydrogenase activity
GII90_01755	COG4175	Glycine betaine
GII90_01760	COG4176	ABC-type proline glycine betaine transport system permease component
GII90_01765	COG2113	Glycine betaine
GII90_01770	COG1473	amidohydrolase
GII90_01775	COG1288	antiporter activity
GII90_01785	COG0366	Alpha amylase catalytic
GII90_01790	COG0039	L-malate dehydrogenase activity
GII90_01795	COG1620	l-lactate permease
GII90_01800	COG2814	Major facilitator Superfamily
GII90_01805	COG1846	Transcriptional regulator
GII90_01810	COG1280	lysine exporter protein (LysE YggA)
GII90_01815	COG3403	YqcI/YcgG family
GII90_01820	COG1113	amino acid transport
GII90_01825	COG3665	Urea carboxylase-associated protein
GII90_01830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII90_01835	COG1660	Displays ATPase and GTPase activities
GII90_01840	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII90_01845	COG2226	methyltransferase
GII90_01850	COG0583	DNA-binding transcription factor activity
GII90_01855	COG3458	cephalosporin-C deacetylase activity
GII90_01860	COG3541	Predicted nucleotidyltransferase
GII90_01865	COG0506	proline dehydrogenase activity
GII90_01870	COG1012	belongs to the aldehyde dehydrogenase family
GII90_01875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII90_01880	COG2508	Transcriptional regulator
GII90_01885	COG3689	TIGRFAM TIGR03943 family protein
GII90_01890	COG0701	Predicted permease
GII90_01895	COG2267	carboxylic ester hydrolase activity
GII90_01900	COG0492	ferredoxin-NADP+ reductase activity
GII90_01905	COG1587	Uroporphyrinogen-III synthase
GII90_01905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII90_01910	COG2146	nitrite reductase [NAD(P)H] activity
GII90_01915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII90_01920	COG0243	molybdopterin cofactor binding
GII90_01925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII90_01930	COG2223	nitrite transmembrane transporter activity
GII90_01935	COG1469	GTP cyclohydrolase I activity
GII90_01940	COG1376	ErfK ybiS ycfS ynhG family protein
GII90_01950	COG0523	cobalamin synthesis protein
GII90_01955	COG0765	amino acid transport
GII90_01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII90_01970	COG1714	RDD family
GII90_01980	COG2723	6-phospho-beta-galactosidase activity
GII90_01990	COG3209	COG3209 Rhs family protein
GII90_01995	COG0840	transmembrane signaling receptor activity
GII90_01995	COG3290	protein histidine kinase activity
GII90_02000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII90_02005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII90_02010	COG1733	regulation of RNA biosynthetic process
GII90_02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_02030	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII90_02035	COG2814	Major facilitator Superfamily
GII90_02045	COG0697	spore germination
GII90_02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII90_02060	COG2364	Membrane
GII90_02065	COG1126	abc transporter atp-binding protein
GII90_02070	COG0765	amino acid transport
GII90_02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII90_02080	COG0583	DNA-binding transcription factor activity
GII90_02085	COG0163	prenyltransferase activity
GII90_02090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII90_02105	COG0596	Alpha beta hydrolase
GII90_02110	COG3104	oligopeptide transport
GII90_02115	COG5434	Belongs to the glycosyl hydrolase 28 family
GII90_02125	COG0697	spore germination
GII90_02135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII90_02140	COG1136	(ABC) transporter
GII90_02145	COG0577	efflux transmembrane transporter activity
GII90_02150	COG0745	RESPONSE REGULATOR receiver
GII90_02155	COG5002	protein histidine kinase activity
GII90_02155	COG3850	Histidine kinase
GII90_02160	COG0457	Tetratricopeptide repeat
GII90_02180	COG0527	aspartate kinase activity
GII90_02185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII90_02190	COG4605	iron ion homeostasis
GII90_02195	COG4604	ABC transporter, ATP-binding protein
GII90_02200	COG4607	ABC-type enterochelin transport system periplasmic component
GII90_02205	COG2814	Major facilitator Superfamily
GII90_02210	COG1309	transcriptional regulator
GII90_02215	COG0778	Nitroreductase
GII90_02220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII90_02225	COG0640	Transcriptional regulator
GII90_02230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII90_02235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII90_02240	COG1012	belongs to the aldehyde dehydrogenase family
GII90_02245	COG4975	Glucose uptake
GII90_02250	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_02255	COG4549	nuclear export factor GLE1
GII90_02260	COG1276	copper resistance
GII90_02260	COG2372	response to copper ion
GII90_02265	COG1349	DNA-binding transcription factor activity
GII90_02275	COG2213	PTS system mannitol-specific
GII90_02280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII90_02285	COG0246	Mannitol dehydrogenase
GII90_02290	COG0473	3-isopropylmalate dehydrogenase activity
GII90_02295	COG0681	Belongs to the peptidase S26 family
GII90_02300	COG0412	Dienelactone hydrolase
GII90_02305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII90_02315	COG0561	phosphatase activity
GII90_02320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII90_02325	COG1914	H( )-stimulated, divalent metal cation uptake system
GII90_02330	COG4336	lyase activity
GII90_02335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII90_02340	COG1984	allophanate hydrolase subunit 2
GII90_02345	COG1414	Transcriptional regulator
GII90_02350	COG2755	lipolytic protein G-D-S-L family
GII90_02360	COG2329	Antibiotic biosynthesis monooxygenase
GII90_02365	COG0768	penicillin binding
GII90_02370	COG4989	oxidoreductase activity
GII90_02375	COG3711	transcriptional antiterminator
GII90_02380	COG0318	PFAM AMP-dependent synthetase and ligase
GII90_02385	COG2226	methyltransferase
GII90_02390	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_02395	COG1917	Cupin 2, conserved barrel domain protein
GII90_02400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII90_02405	COG3871	stress protein (general stress protein 26)
GII90_02415	COG2814	Major facilitator Superfamily
GII90_02420	COG1522	sequence-specific DNA binding
GII90_02425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII90_02425	COG0551	DNA topoisomerase type I activity
GII90_02430	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII90_02435	COG3706	GGDEF domain
GII90_02440	COG5298	Protein conserved in bacteria
GII90_02445	COG1215	transferase activity, transferring glycosyl groups
GII90_02455	COG0531	amino acid
GII90_02460	COG0494	nUDIX hydrolase
GII90_02465	COG0028	Belongs to the TPP enzyme family
GII90_02480	COG1914	H( )-stimulated, divalent metal cation uptake system
GII90_02485	COG2261	transglycosylase associated protein
GII90_02490	COG4876	unkown
GII90_02495	COG2217	Heavy metal translocating P-type atpase
GII90_02500	COG3729	General stress protein
GII90_02505	COG0662	Cupin 2, conserved barrel domain protein
GII90_02510	COG2329	Antibiotic biosynthesis monooxygenase
GII90_02515	COG3546	catalase activity
GII90_02520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII90_02525	COG3290	protein histidine kinase activity
GII90_02530	COG4565	transcriptional regulatory protein
GII90_02535	COG1301	dicarboxylic acid transport
GII90_02540	COG0628	permease
GII90_02545	COG1131	(ABC) transporter
GII90_02550	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII90_02560	COG1960	acyl-CoA dehydrogenase activity
GII90_02575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII90_02580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII90_02585	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII90_02590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII90_02595	COG0513	Belongs to the DEAD box helicase family
GII90_02600	COG3402	PFAM membrane-flanked domain
GII90_02605	COG3428	Bacterial PH domain
GII90_02610	COG0705	Rhomboid family
GII90_02615	COG0736	holo-[acyl-carrier-protein] synthase activity
GII90_02620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII90_02625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII90_02630	COG0864	Transcriptional regulator
GII90_02635	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII90_02640	COG1366	Belongs to the anti-sigma-factor antagonist family
GII90_02645	COG1366	Belongs to the anti-sigma-factor antagonist family
GII90_02650	COG2172	sigma factor antagonist activity
GII90_02655	COG2208	phosphoserine phosphatase activity
GII90_02660	COG1366	Belongs to the anti-sigma-factor antagonist family
GII90_02665	COG2172	sigma factor antagonist activity
GII90_02670	COG1191	sigma factor activity
GII90_02675	COG2208	phosphoserine phosphatase activity
GII90_02690	COG1673	EVE domain
GII90_02695	COG1846	Transcriptional regulator
GII90_02700	COG2183	response to ionizing radiation
GII90_02710	COG3091	SprT-like family
GII90_02750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII90_02755	COG1522	sequence-specific DNA binding
GII90_02760	COG1522	sequence-specific DNA binding
GII90_02765	COG1335	isochorismatase
GII90_02770	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII90_02775	COG2814	Major facilitator Superfamily
GII90_02795	COG0693	protein deglycase activity
GII90_02800	COG1278	Cold shock
GII90_02805	COG1329	Transcriptional regulator
GII90_02815	COG1917	Cupin 2, conserved barrel domain protein
GII90_02815	COG2207	Transcriptional regulator
GII90_02820	COG0697	spore germination
GII90_02825	COG2207	Transcriptional regulator
GII90_02825	COG3708	Transcriptional regulator
GII90_02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII90_02835	COG0477	Major facilitator Superfamily
GII90_02845	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII90_02855	COG0697	spore germination
GII90_02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII90_02865	COG2030	dehydratase
GII90_02870	COG3545	Serine hydrolase
GII90_02875	COG1733	regulation of RNA biosynthetic process
GII90_02880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII90_02885	COG1733	regulation of RNA biosynthetic process
GII90_02890	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII90_02895	COG2814	Major facilitator Superfamily
GII90_02900	COG1309	transcriptional regulator
GII90_02910	COG0640	Transcriptional regulator
GII90_02915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII90_02925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII90_02930	COG0697	spore germination
GII90_02935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII90_02940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII90_02945	COG0640	Transcriptional regulator
GII90_02950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII90_02965	COG4585	Histidine kinase
GII90_02970	COG2197	response regulator
GII90_02975	COG2409	Drug exporters of the RND superfamily
GII90_02980	COG0596	Alpha beta hydrolase
GII90_02985	COG1811	Na channel or pump
GII90_02990	COG0789	Transcriptional regulator
GII90_02990	COG4978	Transcriptional regulator
GII90_02995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII90_03000	COG0778	Nitroreductase
GII90_03005	COG0346	lactoylglutathione lyase activity
GII90_03010	COG2259	Doxx family
GII90_03015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII90_03030	COG2323	membrane
GII90_03035	COG2323	membrane
GII90_03040	COG0071	Belongs to the small heat shock protein (HSP20) family
GII90_03055	COG1309	transcriptional regulator
GII90_03065	COG0456	acetyltransferase
GII90_03075	COG1113	amino acid transport
GII90_03080	COG2318	DinB family
GII90_03085	COG1846	Transcriptional regulator
GII90_03090	COG1033	growth of symbiont in host cell
GII90_03090	COG2409	Drug exporters of the RND superfamily
GII90_03095	COG0778	Nitroreductase
GII90_03100	COG1846	Transcriptional regulator
GII90_03105	COG2814	Major facilitator Superfamily
GII90_03110	COG0730	response to heat
GII90_03115	COG1802	Transcriptional regulator
GII90_03120	COG3858	chitin binding
GII90_03120	COG1388	LysM domain
GII90_03125	COG1819	glycosyl
GII90_03135	COG1785	Belongs to the alkaline phosphatase family
GII90_03140	COG5646	InterPro IPR014922
GII90_03150	COG0454	-acetyltransferase
GII90_03155	COG1078	dGTPase activity
GII90_03160	COG1388	LysM domain
GII90_03165	COG2814	Major facilitator Superfamily
GII90_03170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII90_03175	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII90_03180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII90_03185	COG2723	6-phospho-beta-galactosidase activity
GII90_03190	COG2188	Transcriptional regulator
GII90_03195	COG1940	carbohydrate kinase activity
GII90_03200	COG1482	cell wall glycoprotein biosynthetic process
GII90_03205	COG4124	Belongs to the glycosyl hydrolase 26 family
GII90_03250	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII90_03255	COG0802	atpase or kinase
GII90_03260	COG1214	PFAM Peptidase M22, glycoprotease
GII90_03265	COG0456	acetyltransferase
GII90_03270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII90_03275	COG0488	(ABC) transporter
GII90_03280	COG0315	cyclic pyranopterin monophosphate synthase activity
GII90_03285	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII90_03290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII90_03295	COG0805	protein transport
GII90_03305	COG1266	CAAX protease self-immunity
GII90_03310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GII90_03315	COG0459	protein refolding
GII90_03325	COG3378	Phage plasmid primase P4 family
GII90_03340	COG0270	DNA (cytosine-5-)-methyltransferase activity
GII90_03345	COG0270	DNA (cytosine-5-)-methyltransferase activity
GII90_03365	COG1401	restriction endodeoxyribonuclease activity
GII90_03380	COG1073	alpha beta
GII90_03385	COG0457	Tetratricopeptide repeat
GII90_03390	COG1063	alcohol dehydrogenase
GII90_03395	COG2211	Major facilitator Superfamily
GII90_03400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII90_03405	COG1842	Phage shock protein A
GII90_03410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII90_03415	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII90_03420	COG4260	virion core protein, lumpy skin disease virus
GII90_03430	COG2814	Major facilitator Superfamily
GII90_03435	COG1063	alcohol dehydrogenase
GII90_03440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII90_03445	COG0823	Involved in the tonB-independent uptake of proteins
GII90_03460	COG2267	carboxylic ester hydrolase activity
GII90_03470	COG2132	Multicopper oxidase
GII90_03475	COG1113	amino acid transport
GII90_03485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII90_03490	COG0714	Associated with various cellular activities
GII90_03495	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII90_03500	COG1305	Transglutaminase-like
GII90_03505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII90_03505	COG0519	Catalyzes the synthesis of GMP from XMP
GII90_03510	COG2252	PERMEase
GII90_03515	COG3064	Membrane
GII90_03525	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII90_03535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII90_03540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII90_03545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII90_03550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII90_03555	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII90_03560	COG0047	phosphoribosylformylglycinamidine synthase activity
GII90_03565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII90_03570	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII90_03575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII90_03580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII90_03585	COG0138	bifunctional purine biosynthesis protein purh
GII90_03590	COG0151	Belongs to the GarS family
GII90_03595	COG1522	sequence-specific DNA binding
GII90_03600	COG0531	amino acid
GII90_03610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII90_03615	COG1470	cell adhesion involved in biofilm formation
GII90_03620	COG4496	protein, YerC YecD
GII90_03625	COG0069	glutamate synthase activity
GII90_03630	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII90_03635	COG0210	DNA helicase
GII90_03640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII90_03645	COG4851	CamS sex pheromone cAM373 precursor
GII90_03650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII90_03655	COG1285	pathogenesis
GII90_03660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII90_03665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII90_03670	COG0154	amidase activity
GII90_03675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII90_03680	COG1309	transcriptional regulator
GII90_03685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII90_03690	COG1597	lipid kinase activity
GII90_03695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII90_03700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII90_03705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII90_03710	COG1002	Type II restriction enzyme, methylase subunits
GII90_03715	COG1061	Type III restriction enzyme res subunit
GII90_03720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII90_03740	COG5444	nuclease activity
GII90_03745	COG3391	amine dehydrogenase activity
GII90_03750	COG0457	Tetratricopeptide repeat
GII90_03760	COG0217	transcriptional regulatory protein
GII90_03770	COG1309	transcriptional regulator
GII90_03775	COG3631	Ketosteroid isomerase-related protein
GII90_03780	COG0702	epimerase
GII90_03795	COG3546	catalase activity
GII90_03800	COG0454	-acetyltransferase
GII90_03810	COG5578	integral membrane protein
GII90_03815	COG2972	Histidine kinase
GII90_03820	COG4753	response regulator
GII90_03820	COG2207	Transcriptional regulator
GII90_03825	COG1653	transport
GII90_03830	COG1175	transmembrane transport
GII90_03835	COG0395	ABC-type sugar transport system, permease component
GII90_03840	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII90_03845	COG2207	Transcriptional regulator
GII90_03850	COG2755	lipolytic protein G-D-S-L family
GII90_03860	COG5578	integral membrane protein
GII90_03865	COG3401	FG-GAP repeat protein
GII90_03870	COG3401	FG-GAP repeat protein
GII90_03875	COG2755	lipolytic protein G-D-S-L family
GII90_03880	COG1874	Beta-galactosidase
GII90_03890	COG1653	transport
GII90_03895	COG4209	transmembrane transport
GII90_03900	COG0395	ABC-type sugar transport system, permease component
GII90_03905	COG1486	melibiose metabolic process
GII90_03910	COG2323	membrane
GII90_03915	COG2329	Antibiotic biosynthesis monooxygenase
GII90_03920	COG0346	lactoylglutathione lyase activity
GII90_03935	COG5583	Uncharacterized small protein (DUF2292)
GII90_03940	COG0670	Belongs to the BI1 family
GII90_03945	COG0697	spore germination
GII90_03950	COG1846	Transcriptional regulator
GII90_03955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII90_03965	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII90_03965	COG2124	cytochrome p450
GII90_03970	COG1368	sulfuric ester hydrolase activity
GII90_03975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII90_03980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII90_03985	COG1442	glycosyl transferase family 8
GII90_03990	COG1216	Glycosyl transferase, family 2
GII90_03995	COG1442	glycosyl transferase family 8
GII90_04000	COG2223	nitrite transmembrane transporter activity
GII90_04005	COG1011	Hydrolase
GII90_04010	COG0531	amino acid
GII90_04015	COG1012	belongs to the aldehyde dehydrogenase family
GII90_04020	COG0840	transmembrane signaling receptor activity
GII90_04025	COG0488	(ABC) transporter
GII90_04035	COG0789	Transcriptional regulator
GII90_04040	COG2814	Major facilitator Superfamily
GII90_04050	COG0488	(ABC) transporter
GII90_04055	COG0513	Belongs to the DEAD box helicase family
GII90_04060	COG0456	acetyltransferase
GII90_04065	COG2130	NADP-dependent
GII90_04070	COG2211	Major facilitator Superfamily
GII90_04075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GII90_04080	COG1120	ATPase activity
GII90_04085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII90_04090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII90_04095	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII90_04110	COG3866	Pectate lyase
GII90_04115	COG0471	metal ion transport
GII90_04120	COG3290	protein histidine kinase activity
GII90_04125	COG4565	transcriptional regulatory protein
GII90_04130	COG3181	Tripartite tricarboxylate transporter family receptor
GII90_04135	COG2851	Citrate transporter
GII90_04140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII90_04145	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII90_04150	COG1254	Belongs to the acylphosphatase family
GII90_04155	COG2258	MOSC domain
GII90_04175	COG0024	Methionine aminopeptidase
GII90_04180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_04180	COG1263	PTS System
GII90_04185	COG1368	sulfuric ester hydrolase activity
GII90_04200	COG1115	amino acid carrier protein
GII90_04205	COG0531	amino acid
GII90_04220	COG0697	spore germination
GII90_04225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_04225	COG1263	PTS System
GII90_04230	COG0366	Alpha amylase catalytic
GII90_04235	COG2188	Transcriptional regulator
GII90_04240	COG0778	Nitroreductase
GII90_04245	COG0737	Belongs to the 5'-nucleotidase family
GII90_04250	COG0693	protein deglycase activity
GII90_04255	COG2814	Major facilitator Superfamily
GII90_04260	COG4840	Belongs to the UPF0435 family
GII90_04265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII90_04270	COG4980	gas vesicle protein
GII90_04275	COG1295	ribonuclease BN
GII90_04280	COG0477	Major facilitator Superfamily
GII90_04290	COG0387	Pfam Sodium calcium exchanger
GII90_04300	COG0668	transmembrane transport
GII90_04305	COG0535	radical SAM domain protein
GII90_04315	COG0726	polysaccharide deacetylase
GII90_04320	COG2084	Dehydrogenase
GII90_04325	COG0598	Magnesium transport protein CorA
GII90_04330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII90_04335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII90_04345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII90_04350	COG4637	Psort location Cytoplasmic, score
GII90_04360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII90_04365	COG0022	dehydrogenase e1 component
GII90_04370	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII90_04375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII90_04380	COG3284	Transcriptional regulator
GII90_04390	COG1742	UPF0060 membrane protein
GII90_04415	COG4842	Belongs to the WXG100 family
GII90_04420	COG1486	melibiose metabolic process
GII90_04425	COG1737	Transcriptional regulator
GII90_04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_04430	COG1263	PTS System
GII90_04435	COG1132	(ABC) transporter
GII90_04440	COG1132	(ABC) transporter
GII90_04445	COG2259	Doxx family
GII90_04450	COG2514	catechol 2,3-dioxygenase activity
GII90_04455	COG4977	sequence-specific DNA binding
GII90_04455	COG1917	Cupin 2, conserved barrel domain protein
GII90_04460	COG2814	Major facilitator Superfamily
GII90_04465	COG1082	Xylose isomerase domain protein TIM barrel
GII90_04470	COG0673	inositol 2-dehydrogenase activity
GII90_04475	COG4585	Histidine kinase
GII90_04480	COG2197	response regulator
GII90_04485	COG1131	(ABC) transporter
GII90_04490	COG0842	Transport permease protein
GII90_04490	COG1511	domain protein
GII90_04495	COG0842	Transport permease protein
GII90_04500	COG1695	Transcriptional regulator
GII90_04505	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII90_04510	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII90_04515	COG1309	transcriptional regulator
GII90_04520	COG2814	Major facilitator Superfamily
GII90_04525	COG2318	DinB family
GII90_04530	COG2814	Major facilitator Superfamily
GII90_04535	COG1846	Transcriptional regulator
GII90_04540	COG0392	lysyltransferase activity
GII90_04540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII90_04545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII90_04550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII90_04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII90_04560	COG0384	phenazine biosynthesis protein PhzF
GII90_04565	COG0778	Nitroreductase
GII90_04580	COG1090	epimerase
GII90_04585	COG2137	regulation of response to DNA damage stimulus
GII90_04595	COG2814	Major facilitator Superfamily
GII90_04610	COG3103	Sh3 type 3 domain protein
GII90_04615	COG5658	integral membrane protein
GII90_04620	COG0596	Alpha beta hydrolase
GII90_04625	COG0463	Glycosyl transferase, family 2
GII90_04630	COG4485	Bacterial membrane protein, YfhO
GII90_04635	COG1988	membrane-bound metal-dependent
GII90_04640	COG1194	a g-specific adenine glycosylase
GII90_04650	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_04665	COG3557	Belongs to the UPF0374 family
GII90_04670	COG1132	(ABC) transporter
GII90_04675	COG4129	membrane
GII90_04680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII90_04685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII90_04690	COG0735	belongs to the Fur family
GII90_04800	COG4326	sporulation control protein
GII90_04810	COG5577	PFAM Coat F domain
GII90_04815	COG3340	Belongs to the peptidase S51 family
GII90_04820	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII90_04825	COG0277	FAD linked oxidase domain protein
GII90_04835	COG0753	catalase activity
GII90_04840	COG1116	anion transmembrane transporter activity
GII90_04845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII90_04850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII90_04855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII90_04865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII90_04875	COG1476	TRANSCRIPTIONal
GII90_04885	COG3382	B3 4 domain protein
GII90_04890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII90_04900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII90_04905	COG0789	Transcriptional regulator
GII90_04910	COG1664	Polymer-forming cytoskeletal
GII90_04915	COG1664	Polymer-forming cytoskeletal
GII90_04920	COG2766	serine protein kinase
GII90_04925	COG2718	Belongs to the UPF0229 family
GII90_04930	COG1846	Transcriptional regulator
GII90_04935	COG1566	PFAM secretion protein HlyD family protein
GII90_04940	COG2814	Major facilitator Superfamily
GII90_04945	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII90_04965	COG1725	Transcriptional regulator
GII90_04970	COG1131	(ABC) transporter
GII90_04975	COG1131	(ABC) transporter
GII90_04980	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII90_04985	COG1278	Cold shock
GII90_04990	COG1464	Belongs to the NlpA lipoprotein family
GII90_04995	COG3706	GGDEF domain
GII90_05000	COG1823	symporter activity
GII90_05020	COG5577	PFAM Coat F domain
GII90_05025	COG4085	toxin activity
GII90_05025	COG1525	nuclease
GII90_05025	COG0737	Belongs to the 5'-nucleotidase family
GII90_05030	COG3764	Sortase (surface protein transpeptidase)
GII90_05035	COG0564	pseudouridine synthase activity
GII90_05045	COG0517	IMP dehydrogenase activity
GII90_05050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII90_05055	COG3153	acetyltransferase
GII90_05055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII90_05060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII90_05065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII90_05070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII90_05075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII90_05080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII90_05085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII90_05090	COG2203	Gaf domain
GII90_05090	COG4585	Histidine kinase
GII90_05095	COG2197	response regulator
GII90_05100	COG0431	NADPH-dependent FMN reductase
GII90_05115	COG1388	LysM domain
GII90_05115	COG0791	NLP P60 protein
GII90_05120	COG1959	2 iron, 2 sulfur cluster binding
GII90_05125	COG0668	transmembrane transport
GII90_05130	COG2719	SpoVR family
GII90_05135	COG1785	Belongs to the alkaline phosphatase family
GII90_05140	COG0791	NLP P60 protein
GII90_05140	COG1388	LysM domain
GII90_05145	COG0583	DNA-binding transcription factor activity
GII90_05150	COG0372	Belongs to the citrate synthase family
GII90_05155	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_05160	COG0531	amino acid
GII90_05165	COG0733	neurotransmitter:sodium symporter activity
GII90_05170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII90_05175	COG0456	acetyltransferase
GII90_05190	COG1595	DNA-templated transcription, initiation
GII90_05195	COG0667	Aldo Keto reductase
GII90_05200	COG0204	Acyl-transferase
GII90_05205	COG1253	flavin adenine dinucleotide binding
GII90_05210	COG0789	Transcriptional regulator
GII90_05215	COG0436	Aminotransferase
GII90_05220	COG1253	flavin adenine dinucleotide binding
GII90_05225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII90_05230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII90_05235	COG0584	glycerophosphoryl diester phosphodiesterase
GII90_05245	COG0668	transmembrane transport
GII90_05250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII90_05255	COG0726	polysaccharide deacetylase
GII90_05260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII90_05265	COG1757	Na H antiporter
GII90_05270	COG0589	response to stress
GII90_05280	COG1132	(ABC) transporter
GII90_05285	COG1132	(ABC) transporter
GII90_05290	COG0702	epimerase
GII90_05310	COG0189	ligase activity
GII90_05315	COG0189	ligase activity
GII90_05320	COG4399	Belongs to the UPF0754 family
GII90_05325	COG3679	Belongs to the UPF0342 family
GII90_05330	COG4335	DNA alkylation repair
GII90_05335	COG0561	phosphatase activity
GII90_05340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII90_05345	COG0475	glutathione-regulated potassium exporter activity
GII90_05350	COG0490	domain, Protein
GII90_05360	COG1024	Enoyl-CoA hydratase
GII90_05370	COG4152	abc transporter atp-binding protein
GII90_05375	COG1668	transmembrane transport
GII90_05380	COG0420	3'-5' exonuclease activity
GII90_05385	COG4717	serine-type aminopeptidase activity
GII90_05390	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII90_05400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII90_05430	COG1846	Transcriptional regulator
GII90_05435	COG4980	gas vesicle protein
GII90_05450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII90_05455	COG0537	adenosine 5'-monophosphoramidase activity
GII90_05460	COG1131	(ABC) transporter
GII90_05465	COG4473	ABC transporter
GII90_05475	COG1473	amidohydrolase
GII90_05480	COG3069	C4-dicarboxylate transmembrane transporter activity
GII90_05490	COG2329	Antibiotic biosynthesis monooxygenase
GII90_05495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII90_05500	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII90_05515	COG1309	transcriptional regulator
GII90_05520	COG1511	domain protein
GII90_05525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII90_05530	COG4377	Putative membrane peptidase family (DUF2324)
GII90_05540	COG1363	Peptidase, m42
GII90_05545	COG4405	Protein conserved in bacteria
GII90_05550	COG1301	dicarboxylic acid transport
GII90_05560	COG1234	tRNA 3'-trailer cleavage
GII90_05565	COG0095	Lipoate-protein ligase
GII90_05570	COG0702	epimerase
GII90_05575	COG0318	PFAM AMP-dependent synthetase and ligase
GII90_05585	COG0501	Belongs to the peptidase M48B family
GII90_05590	COG1404	Belongs to the peptidase S8 family
GII90_05595	COG0456	acetyltransferase
GII90_05600	COG0604	alcohol dehydrogenase
GII90_05605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII90_05610	COG0406	alpha-ribazole phosphatase activity
GII90_05615	COG0183	Belongs to the thiolase family
GII90_05620	COG0318	PFAM AMP-dependent synthetase and ligase
GII90_05625	COG1268	BioY protein
GII90_05630	COG0840	transmembrane signaling receptor activity
GII90_05635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII90_05635	COG0723	plastoquinol--plastocyanin reductase activity
GII90_05640	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_05650	COG4903	ComK protein
GII90_05655	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_05665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII90_05680	COG0398	Pfam SNARE associated Golgi protein
GII90_05685	COG0681	Belongs to the peptidase S26 family
GII90_05690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII90_05695	COG1846	Transcriptional regulator
GII90_05700	COG0738	Major facilitator superfamily
GII90_05705	COG0673	inositol 2-dehydrogenase activity
GII90_05710	COG0561	phosphatase activity
GII90_05715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII90_05720	COG1609	Transcriptional regulator
GII90_05725	COG3180	Ammonia monooxygenase
GII90_05730	COG2814	Major facilitator Superfamily
GII90_05730	COG0477	Major facilitator Superfamily
GII90_05735	COG4533	DNA binding
GII90_05750	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII90_05755	COG1074	ATP-dependent DNA helicase activity
GII90_05760	COG0420	3'-5' exonuclease activity
GII90_05765	COG0419	ATPase involved in DNA repair
GII90_05770	COG1403	HNH endonuclease
GII90_05810	COG5337	Spore coat protein CotH
GII90_05815	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII90_05825	COG1404	Belongs to the peptidase S8 family
GII90_05835	COG0367	asparagine synthase
GII90_05840	COG2318	DinB family
GII90_05845	COG1562	ergosterol biosynthetic process
GII90_05850	COG0534	Mate efflux family protein
GII90_05855	COG2207	Transcriptional regulator
GII90_05855	COG1917	Cupin 2, conserved barrel domain protein
GII90_05860	COG1609	Transcriptional regulator
GII90_05865	COG0673	inositol 2-dehydrogenase activity
GII90_05870	COG2318	DinB family
GII90_05875	COG1279	arginine transmembrane transporter activity
GII90_05880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII90_05885	COG1357	PFAM Pentapeptide repeats (8 copies)
GII90_05890	COG2267	carboxylic ester hydrolase activity
GII90_05895	COG0529	Catalyzes the synthesis of activated sulfate
GII90_05900	COG2046	Belongs to the sulfate adenylyltransferase family
GII90_05905	COG0175	sulfate reduction
GII90_05910	COG2045	Belongs to the ComB family
GII90_05915	COG1809	phosphosulfolactate synthase activity
GII90_05920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII90_05925	COG4948	Mandelate Racemase Muconate Lactonizing
GII90_05930	COG2814	Major facilitator Superfamily
GII90_05935	COG0454	-acetyltransferase
GII90_05940	COG2153	protein acetylation
GII90_05945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII90_05945	COG0646	methionine synthase
GII90_05955	COG2996	Protein conserved in bacteria
GII90_05975	COG1695	Transcriptional regulator
GII90_05990	COG3227	Zinc metalloprotease (Elastase)
GII90_05995	COG1307	EDD domain protein, DegV family
GII90_06000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII90_06015	COG0561	phosphatase activity
GII90_06020	COG1073	alpha beta
GII90_06025	COG2151	metal-sulfur cluster biosynthetic enzyme
GII90_06035	COG0277	FAD linked oxidase domain protein
GII90_06040	COG2271	Major facilitator Superfamily
GII90_06045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII90_06060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII90_06065	COG0505	Belongs to the CarA family
GII90_06070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII90_06075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII90_06090	COG2267	carboxylic ester hydrolase activity
GII90_06100	COG1744	ABC transporter substrate-binding protein PnrA-like
GII90_06115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII90_06120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII90_06125	COG5504	Zn-dependent protease
GII90_06130	COG0444	Belongs to the ABC transporter superfamily
GII90_06135	COG4608	Belongs to the ABC transporter superfamily
GII90_06145	COG0601	transmembrane transport
GII90_06150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII90_06160	COG0180	Tryptophanyl-tRNA synthetase
GII90_06165	COG4166	transmembrane transport
GII90_06170	COG0601	transmembrane transport
GII90_06175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII90_06180	COG0444	Belongs to the ABC transporter superfamily
GII90_06185	COG4608	Belongs to the ABC transporter superfamily
GII90_06190	COG2814	Major facilitator Superfamily
GII90_06195	COG0456	acetyltransferase
GII90_06200	COG1393	Belongs to the ArsC family
GII90_06205	COG0861	Integral membrane protein TerC family
GII90_06215	COG4862	establishment of competence for transformation
GII90_06225	COG4469	Competence protein
GII90_06230	COG1164	Oligoendopeptidase f
GII90_06245	COG2346	COG2346, Truncated hemoglobins
GII90_06250	COG0741	lytic transglycosylase activity
GII90_06255	COG4116	CYTH
GII90_06265	COG2357	RelA SpoT domain protein
GII90_06270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII90_06275	COG0564	pseudouridine synthase activity
GII90_06280	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII90_06285	COG0475	glutathione-regulated potassium exporter activity
GII90_06285	COG0569	domain protein
GII90_06290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII90_06295	COG0352	thiamine-phosphate diphosphorylase activity
GII90_06300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII90_06305	COG2104	thiamine diphosphate biosynthetic process
GII90_06310	COG2022	thiamine diphosphate biosynthetic process
GII90_06315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII90_06320	COG0351	phosphomethylpyrimidine kinase
GII90_06325	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII90_06380	COG0210	DNA helicase
GII90_06390	COG2153	protein acetylation
GII90_06395	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII90_06400	COG2382	esterase
GII90_06405	COG0626	cystathionine gamma-synthase activity
GII90_06410	COG0626	cystathionine gamma-synthase activity
GII90_06415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII90_06420	COG5505	Protein of unknown function (DUF819)
GII90_06450	COG3677	Transposase
GII90_06465	COG5484	DNA packaging
GII90_06470	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII90_06475	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_06485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII90_06485	COG3711	transcriptional antiterminator
GII90_06490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII90_06490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII90_06490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII90_06495	COG1482	cell wall glycoprotein biosynthetic process
GII90_06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII90_06515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII90_06530	COG0109	protoheme IX farnesyltransferase activity
GII90_06540	COG0726	polysaccharide deacetylase
GII90_06555	COG5504	Zn-dependent protease
GII90_06560	COG2205	protein histidine kinase activity
GII90_06570	COG3383	formate dehydrogenase (NAD+) activity
GII90_06575	COG2427	Protein of unknown function (DUF1641)
GII90_06585	COG1051	belongs to the nudix hydrolase family
GII90_06595	COG2124	cytochrome p450
GII90_06600	COG1819	glycosyl
GII90_06610	COG1587	Uroporphyrinogen-III synthase
GII90_06615	COG0390	transport system, permease component
GII90_06620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII90_06625	COG0697	spore germination
GII90_06630	COG4297	protein containing double-stranded beta helix domain
GII90_06640	COG1252	NADH dehydrogenase
GII90_06645	COG1904	glucuronate isomerase
GII90_06650	COG2211	Major facilitator Superfamily
GII90_06655	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII90_06660	COG1063	alcohol dehydrogenase
GII90_06665	COG1312	Catalyzes the dehydration of D-mannonate
GII90_06670	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_06675	COG2271	Major facilitator Superfamily
GII90_06680	COG1609	Transcriptional regulator
GII90_06685	COG0246	Mannitol dehydrogenase
GII90_06690	COG2721	sulfolactate sulfo-lyase activity
GII90_06695	COG0730	response to heat
GII90_06700	COG2318	DinB family
GII90_06705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII90_06710	COG0457	Tetratricopeptide repeat
GII90_06720	COG2350	Protein conserved in bacteria
GII90_06725	COG1388	LysM domain
GII90_06725	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII90_06725	COG3409	Peptidoglycan-binding domain 1 protein
GII90_06735	COG4195	phage-related replication protein
GII90_06740	COG3546	catalase activity
GII90_06745	COG2856	Zn peptidase
GII90_06750	COG1396	sequence-specific DNA binding
GII90_06760	COG1522	sequence-specific DNA binding
GII90_06765	COG1484	DNA-dependent DNA replication
GII90_06785	COG1595	DNA-templated transcription, initiation
GII90_06790	COG3728	DNA packaging
GII90_06790	COG5484	DNA packaging
GII90_06795	COG1783	phage Terminase large subunit
GII90_06800	COG5518	Phage portal protein
GII90_06805	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII90_06810	COG4653	Phage capsid family
GII90_06860	COG5412	phage tail tape measure protein
GII90_06860	COG3953	SLT domain
GII90_06865	COG1652	LysM domain
GII90_06870	COG4193	domain, Protein
GII90_06880	COG3628	GPW Gp25 family protein
GII90_06885	COG3299	homolog of phage Mu protein gp47
GII90_06890	COG3778	Protein conserved in bacteria
GII90_06930	COG3409	Peptidoglycan-binding domain 1 protein
GII90_06930	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII90_06950	COG0306	phosphate transporter
GII90_06955	COG1392	Phosphate transport regulator
GII90_06960	COG0531	amino acid
GII90_06965	COG0346	lactoylglutathione lyase activity
GII90_06975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII90_06980	COG0463	Glycosyl transferase, family 2
GII90_06985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII90_06990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII90_06995	COG2362	D-Aminopeptidase
GII90_07000	COG0601	transmembrane transport
GII90_07005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII90_07010	COG0444	Belongs to the ABC transporter superfamily
GII90_07015	COG4166	transmembrane transport
GII90_07020	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII90_07025	COG4948	Mandelate Racemase Muconate Lactonizing
GII90_07030	COG0791	NLP P60 protein
GII90_07035	COG4608	Belongs to the ABC transporter superfamily
GII90_07040	COG2706	6-phosphogluconolactonase activity
GII90_07045	COG1834	amidinotransferase
GII90_07050	COG1607	acyl-coa hydrolase
GII90_07055	COG1017	nitric oxide dioxygenase activity
GII90_07055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII90_07065	COG2323	membrane
GII90_07070	COG2318	DinB family
GII90_07075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII90_07080	COG2076	Multidrug Resistance protein
GII90_07085	COG2076	Multidrug Resistance protein
GII90_07090	COG0788	formyltetrahydrofolate deformylase activity
GII90_07095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII90_07100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII90_07105	COG1764	response to oxidative stress
GII90_07110	COG1846	Transcriptional regulator
GII90_07115	COG1764	response to oxidative stress
GII90_07125	COG0590	tRNA wobble adenosine to inosine editing
GII90_07130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII90_07135	COG1404	Belongs to the peptidase S8 family
GII90_07140	COG1366	Belongs to the anti-sigma-factor antagonist family
GII90_07145	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII90_07150	COG1122	ATPase activity
GII90_07155	COG4721	ABC-type cobalt transport system, permease component
GII90_07165	COG0745	RESPONSE REGULATOR receiver
GII90_07170	COG5002	protein histidine kinase activity
GII90_07170	COG3850	Histidine kinase
GII90_07175	COG3212	peptidase
GII90_07180	COG3212	peptidase
GII90_07190	COG2239	Acts as a magnesium transporter
GII90_07195	COG0789	Transcriptional regulator
GII90_07210	COG1846	Transcriptional regulator
GII90_07215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII90_07220	COG0726	polysaccharide deacetylase
GII90_07225	COG1408	metallophosphoesterase
GII90_07235	COG0463	Glycosyl transferase, family 2
GII90_07240	COG1793	dna ligase
GII90_07240	COG3285	dna ligase
GII90_07245	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII90_07250	COG5001	Diguanylate cyclase
GII90_07250	COG3300	MHYT domain
GII90_07255	COG0586	Pfam SNARE associated Golgi protein
GII90_07260	COG0861	Integral membrane protein TerC family
GII90_07265	COG1191	sigma factor activity
GII90_07285	COG0501	Belongs to the peptidase M48B family
GII90_07290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII90_07305	COG3594	Acyltransferase
GII90_07310	COG5002	protein histidine kinase activity
GII90_07315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII90_07325	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII90_07330	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII90_07335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII90_07340	COG0436	Aminotransferase
GII90_07350	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII90_07355	COG0235	Class ii aldolase
GII90_07360	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII90_07365	COG3339	Conserved Protein
GII90_07380	COG3852	Histidine kinase
GII90_07385	COG1846	Transcriptional regulator
GII90_07390	COG1360	Flagellar Motor Protein
GII90_07395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII90_07400	COG0542	response to heat
GII90_07405	COG3949	Membrane
GII90_07410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII90_07415	COG0720	synthase
GII90_07420	COG0602	queuosine metabolic process
GII90_07425	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII90_07430	COG1733	regulation of RNA biosynthetic process
GII90_07435	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_07440	COG4641	Protein conserved in bacteria
GII90_07440	COG1388	LysM domain
GII90_07445	COG1388	LysM domain
GII90_07460	COG4873	Protein conserved in bacteria
GII90_07470	COG3773	Cell wall hydrolase
GII90_07475	COG2244	polysaccharide biosynthetic process
GII90_07480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII90_07485	COG2217	Heavy metal translocating P-type atpase
GII90_07495	COG0006	proline dipeptidase activity
GII90_07500	COG1609	Transcriptional regulator
GII90_07505	COG3711	transcriptional antiterminator
GII90_07510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_07510	COG2190	(PTS) system
GII90_07510	COG1263	PTS System
GII90_07515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII90_07520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII90_07530	COG1533	DNA photolyase activity
GII90_07535	COG0456	acetyltransferase
GII90_07540	COG0840	transmembrane signaling receptor activity
GII90_07545	COG2084	Dehydrogenase
GII90_07550	COG2340	Cysteine-rich secretory protein family
GII90_07555	COG0768	penicillin binding
GII90_07560	COG4191	Histidine kinase
GII90_07565	COG0436	Aminotransferase
GII90_07575	COG0835	chemotaxis
GII90_07575	COG0784	Response regulator, receiver
GII90_07585	COG2814	Major facilitator Superfamily
GII90_07590	COG1376	ErfK ybiS ycfS ynhG family protein
GII90_07595	COG1408	metallophosphoesterase
GII90_07600	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_07605	COG3409	Peptidoglycan-binding domain 1 protein
GII90_07610	COG3409	Peptidoglycan-binding domain 1 protein
GII90_07620	COG2200	EAL domain
GII90_07630	COG4703	Protein of unknown function (DUF1797)
GII90_07635	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII90_07645	COG0517	IMP dehydrogenase activity
GII90_07650	COG0583	DNA-binding transcription factor activity
GII90_07655	COG0716	FMN binding
GII90_07665	COG0716	FMN binding
GII90_07670	COG2171	N-acyltransferase activity
GII90_07675	COG1473	amidohydrolase
GII90_07685	COG0668	transmembrane transport
GII90_07690	COG0450	alkyl hydroperoxide reductase
GII90_07695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII90_07710	COG0746	molybdenum cofactor guanylyltransferase activity
GII90_07715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII90_07720	COG0303	'Molybdopterin
GII90_07725	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII90_07730	COG0314	molybdopterin synthase activity
GII90_07735	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII90_07740	COG1132	(ABC) transporter
GII90_07745	COG1132	(ABC) transporter
GII90_07755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII90_07760	COG1136	(ABC) transporter
GII90_07765	COG0577	efflux transmembrane transporter activity
GII90_07770	COG1349	DNA-binding transcription factor activity
GII90_07775	COG1105	Belongs to the carbohydrate kinase PfkB family
GII90_07780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII90_07780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII90_07780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII90_07785	COG0681	Belongs to the peptidase S26 family
GII90_07795	COG0488	(ABC) transporter
GII90_07800	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII90_07805	COG2309	aminopeptidase activity
GII90_07815	COG1077	Cell shape determining protein MreB Mrl
GII90_07820	COG2002	toxin-antitoxin pair type II binding
GII90_07825	COG3852	Histidine kinase
GII90_07830	COG2105	PFAM AIG2 family protein
GII90_07830	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII90_07835	COG0569	domain protein
GII90_07840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII90_07845	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII90_07855	COG0561	phosphatase activity
GII90_07860	COG0242	peptide deformylase activity
GII90_07870	COG0497	DNA recombination
GII90_07875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII90_07880	COG0022	dehydrogenase e1 component
GII90_07885	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII90_07890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII90_07895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII90_07905	COG1982	Orn Lys Arg decarboxylase major
GII90_07910	COG4476	Belongs to the UPF0223 family
GII90_07915	COG4493	Belongs to the UPF0637 family
GII90_07925	COG0483	inositol monophosphate 1-phosphatase activity
GII90_07935	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII90_07955	COG1595	DNA-templated transcription, initiation
GII90_07985	COG4896	Protein conserved in bacteria
GII90_07995	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII90_08000	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII90_08005	COG2066	Belongs to the glutaminase family
GII90_08010	COG4838	Belongs to the UPF0358 family
GII90_08015	COG0772	Belongs to the SEDS family
GII90_08020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII90_08025	COG1612	heme a metabolic process
GII90_08030	COG0109	protoheme IX farnesyltransferase activity
GII90_08035	COG2010	Cytochrome c
GII90_08035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII90_08040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII90_08045	COG1845	cytochrome c oxidase, subunit III
GII90_08050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII90_08055	COG3336	cytochrome c oxidase
GII90_08065	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII90_08070	COG2340	Cysteine-rich secretory protein family
GII90_08085	COG3679	Belongs to the UPF0342 family
GII90_08090	COG4471	UPF0298 protein
GII90_08095	COG0742	ribosomal rna small subunit methyltransferase
GII90_08100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII90_08105	COG3314	Sporulation integral membrane protein YlbJ
GII90_08110	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII90_08115	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII90_08120	COG1323	Belongs to the UPF0348 family
GII90_08130	COG1399	metal-binding, possibly nucleic acid-binding protein
GII90_08135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GII90_08145	COG0454	-acetyltransferase
GII90_08150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII90_08155	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII90_08160	COG2001	Belongs to the MraZ family
GII90_08165	COG0275	rRNA processing
GII90_08170	COG4839	cell division protein FtsL
GII90_08180	COG0768	penicillin binding
GII90_08185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII90_08190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII90_08195	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII90_08200	COG0772	Belongs to the SEDS family
GII90_08205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII90_08210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII90_08215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII90_08220	COG3879	Bacterial protein of unknown function (DUF881)
GII90_08225	COG3879	Bacterial protein of unknown function (DUF881)
GII90_08230	COG3856	small basic protein
GII90_08235	COG0849	cell division
GII90_08240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII90_08245	COG4412	M6 family metalloprotease domain protein
GII90_08245	COG1404	Belongs to the peptidase S8 family
GII90_08255	COG1191	sigma factor activity
GII90_08260	COG1191	sigma factor activity
GII90_08265	COG1119	ATPase activity
GII90_08270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII90_08275	COG1873	PFAM PRC-barrel domain
GII90_08285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII90_08290	COG1799	cell septum assembly
GII90_08295	COG0762	integral membrane protein
GII90_08300	COG2302	S4 RNA-binding domain
GII90_08305	COG3599	regulation of cell shape
GII90_08310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII90_08315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII90_08320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII90_08325	COG0564	pseudouridine synthase activity
GII90_08330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII90_08335	COG2233	PERMEase
GII90_08340	COG0540	Belongs to the ATCase OTCase family
GII90_08345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII90_08350	COG0505	Belongs to the CarA family
GII90_08355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII90_08360	COG0543	2 iron, 2 sulfur cluster binding
GII90_08365	COG0167	dihydroorotate dehydrogenase activity
GII90_08370	COG0284	orotidine-5'-phosphate decarboxylase activity
GII90_08375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII90_08380	COG0175	sulfate reduction
GII90_08385	COG0306	phosphate transporter
GII90_08390	COG2046	Belongs to the sulfate adenylyltransferase family
GII90_08395	COG0529	Catalyzes the synthesis of activated sulfate
GII90_08400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII90_08405	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII90_08410	COG1648	precorrin-2 dehydrogenase activity
GII90_08420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII90_08425	COG1561	YicC-like family, N-terminal region
GII90_08430	COG2052	Domain of unknown function (DUF370)
GII90_08435	COG0194	GDP metabolic process
GII90_08440	COG1758	RNA polymerase activity
GII90_08445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII90_08450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII90_08455	COG0242	peptide deformylase activity
GII90_08460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII90_08465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII90_08465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII90_08470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII90_08475	COG0631	protein serine/threonine phosphatase activity
GII90_08480	COG0515	serine threonine protein kinase
GII90_08480	COG2815	serine threonine protein kinase
GII90_08485	COG1162	GTPase activity
GII90_08490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII90_08495	COG1564	THIamine pyrophosphokinase
GII90_08505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII90_08510	COG1302	Protein conserved in bacteria
GII90_08515	COG1461	Dihydroxyacetone kinase
GII90_08520	COG1760	l-serine dehydratase
GII90_08525	COG1760	l-serine dehydratase
GII90_08530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII90_08535	COG1349	DNA-binding transcription factor activity
GII90_08535	COG2050	protein possibly involved in aromatic compounds catabolism
GII90_08540	COG0416	fatty acid biosynthetic process
GII90_08545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII90_08550	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII90_08560	COG0571	ribonuclease III activity
GII90_08565	COG1196	nuclear chromosome segregation
GII90_08570	COG0552	protein localization to endoplasmic reticulum
GII90_08580	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII90_08585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII90_08590	COG0228	four-way junction DNA binding
GII90_08595	COG1837	Belongs to the UPF0109 family
GII90_08605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII90_08610	COG0336	Belongs to the RNA methyltransferase TrmD family
GII90_08615	COG0335	large ribosomal subunit rRNA binding
GII90_08620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII90_08625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII90_08635	COG2257	FlhB HrpN YscU SpaS Family
GII90_08640	COG0045	succinate-CoA ligase (ADP-forming) activity
GII90_08645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII90_08650	COG0758	DNA mediated transformation
GII90_08655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII90_08660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII90_08665	COG4974	Belongs to the 'phage' integrase family
GII90_08670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII90_08675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII90_08680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII90_08685	COG1815	bacterial-type flagellum-dependent cell motility
GII90_08690	COG1558	bacterial-type flagellum-dependent cell motility
GII90_08695	COG1677	Flagellar hook-basal body complex protein FliE
GII90_08700	COG1766	The M ring may be actively involved in energy transduction
GII90_08705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII90_08710	COG1317	bacterial-type flagellum organization
GII90_08715	COG1157	protein secretion by the type III secretion system
GII90_08720	COG2882	bacterial-type flagellum organization
GII90_08725	COG3334	PFAM MgtE intracellular
GII90_08730	COG3144	bacterial-type flagellum assembly
GII90_08735	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII90_08740	COG4786	Flagellar basal body rod
GII90_08745	COG1582	Flagellar protein (FlbD)
GII90_08750	COG1580	Controls the rotational direction of flagella during chemotaxis
GII90_08755	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII90_08760	COG1776	CheC inhibitor of MCP methylation
GII90_08760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII90_08765	COG2201	protein-glutamate methylesterase activity
GII90_08770	COG3190	flagellar
GII90_08775	COG1338	Plays a role in the flagellum-specific transport system
GII90_08780	COG1987	bacterial-type flagellum assembly
GII90_08785	COG1684	flagellar biosynthetic protein fliR
GII90_08790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII90_08795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII90_08800	COG1419	protein localization to endoplasmic reticulum
GII90_08805	COG0455	bacterial-type flagellum organization
GII90_08810	COG2201	protein-glutamate methylesterase activity
GII90_08815	COG2198	Histidine kinase
GII90_08815	COG0643	Histidine kinase
GII90_08820	COG0835	chemotaxis
GII90_08825	COG1776	CheC inhibitor of MCP methylation
GII90_08830	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII90_08835	COG1191	sigma factor activity
GII90_08845	COG0052	Belongs to the universal ribosomal protein uS2 family
GII90_08850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII90_08855	COG0528	UMP kinase activity
GII90_08860	COG0233	cytoplasmic translational termination
GII90_08865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII90_08870	COG4589	Belongs to the CDS family
GII90_08875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII90_08880	COG0750	zinc metalloprotease
GII90_08885	COG0442	prolyl-tRNA aminoacylation
GII90_08890	COG2176	DNA-directed DNA polymerase activity
GII90_08895	COG0779	Required for maturation of 30S ribosomal subunits
GII90_08900	COG0195	Participates in both transcription termination and antitermination
GII90_08905	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII90_08910	COG1358	cellular component organization or biogenesis
GII90_08915	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII90_08920	COG1550	Protein conserved in bacteria
GII90_08925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII90_08930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII90_08935	COG0196	riboflavin kinase activity
GII90_08940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII90_08945	COG1185	polyribonucleotide nucleotidyltransferase activity
GII90_08950	COG0726	polysaccharide deacetylase
GII90_08955	COG0612	Peptidase, M16
GII90_08960	COG1873	PFAM PRC-barrel domain
GII90_08965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII90_08970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII90_08975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII90_08980	COG0527	aspartate kinase activity
GII90_08985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII90_08990	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII90_08995	COG0740	serine-type endopeptidase activity
GII90_09005	COG1674	ftsk spoiiie
GII90_09005	COG4980	gas vesicle protein
GII90_09010	COG2188	Transcriptional regulator
GII90_09015	COG2814	Major facilitator Superfamily
GII90_09020	COG0612	Peptidase, M16
GII90_09025	COG0612	Peptidase, M16
GII90_09030	COG0300	oxidoreductase activity
GII90_09045	COG1426	Protein conserved in bacteria
GII90_09050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII90_09055	COG1546	Belongs to the CinA family
GII90_09055	COG1058	Belongs to the CinA family
GII90_09060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII90_09065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII90_09070	COG1418	mRNA catabolic process
GII90_09075	COG1692	metallophosphoesterase
GII90_09080	COG2359	stage V sporulation protein S
GII90_09085	COG1063	alcohol dehydrogenase
GII90_09090	COG0156	8-amino-7-oxononanoate synthase activity
GII90_09095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII90_09100	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII90_09110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII90_09115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII90_09130	COG3226	Transcriptional regulator
GII90_09135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII90_09145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII90_09150	COG3321	synthase
GII90_09155	COG2070	2-Nitropropane dioxygenase
GII90_09155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII90_09160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII90_09165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII90_09170	COG3425	synthase
GII90_09175	COG1024	Enoyl-CoA hydratase
GII90_09180	COG1024	Enoyl-CoA hydratase
GII90_09185	COG3321	synthase
GII90_09185	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_09185	COG0318	PFAM AMP-dependent synthetase and ligase
GII90_09185	COG0300	oxidoreductase activity
GII90_09190	COG4221	oxidoreductase activity
GII90_09190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII90_09190	COG3321	synthase
GII90_09190	COG0300	oxidoreductase activity
GII90_09195	COG3321	synthase
GII90_09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_09195	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_09195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII90_09195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII90_09200	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_09200	COG4221	oxidoreductase activity
GII90_09200	COG3321	synthase
GII90_09200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_09205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GII90_09205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII90_09205	COG3321	synthase
GII90_09205	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII90_09210	COG2124	cytochrome p450
GII90_09220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII90_09225	COG1404	Belongs to the peptidase S8 family
GII90_09230	COG4195	phage-related replication protein
GII90_09235	COG1764	response to oxidative stress
GII90_09240	COG2076	Multidrug Resistance protein
GII90_09245	COG2076	Multidrug Resistance protein
GII90_09260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII90_09265	COG1923	regulation of RNA biosynthetic process
GII90_09280	COG1780	Probably involved in ribonucleotide reductase function
GII90_09285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII90_09290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII90_09295	COG4112	unkown
GII90_09300	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII90_09305	COG0464	growth
GII90_09310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII90_09315	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII90_09320	COG0789	Transcriptional regulator
GII90_09325	COG0174	glutamine synthetase
GII90_09345	COG4282	regulation of fungal-type cell wall biogenesis
GII90_09355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII90_09385	COG0135	phosphoribosylanthranilate isomerase activity
GII90_09390	COG2211	Major facilitator Superfamily
GII90_09395	COG3507	Belongs to the glycosyl hydrolase 43 family
GII90_09400	COG1940	carbohydrate kinase activity
GII90_09405	COG2115	Belongs to the xylose isomerase family
GII90_09410	COG1070	Carbohydrate kinase
GII90_09420	COG1525	nuclease
GII90_09425	COG2814	Major facilitator Superfamily
GII90_09430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII90_09440	COG0756	dUTP diphosphatase activity
GII90_09455	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII90_09480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII90_09495	COG3832	glyoxalase III activity
GII90_09505	COG0697	spore germination
GII90_09510	COG0531	amino acid
GII90_09540	COG4195	phage-related replication protein
GII90_09550	COG0346	lactoylglutathione lyase activity
GII90_09555	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII90_09560	COG1388	LysM domain
GII90_09565	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII90_09570	COG4224	UPF0291 protein
GII90_09575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII90_09585	COG3763	UPF0154 protein
GII90_09595	COG0785	Cytochrome C biogenesis protein
GII90_09600	COG2201	protein-glutamate methylesterase activity
GII90_09605	COG4846	Membrane protein involved in cytochrome C biogenesis
GII90_09615	COG0071	Belongs to the small heat shock protein (HSP20) family
GII90_09630	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII90_09635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII90_09655	COG0824	Thioesterase
GII90_09665	COG4841	protein insertion into membrane
GII90_09670	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII90_09675	COG1832	CoA-binding protein
GII90_09680	COG0187	DNA topoisomerase II activity
GII90_09685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII90_09695	COG1115	amino acid carrier protein
GII90_09700	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GII90_09710	COG5520	Belongs to the glycosyl hydrolase 30 family
GII90_09715	COG3507	Belongs to the glycosyl hydrolase 43 family
GII90_09720	COG2246	polysaccharide biosynthetic process
GII90_09725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII90_09730	COG0586	Pfam SNARE associated Golgi protein
GII90_09735	COG2404	hydrolase activity, acting on ester bonds
GII90_09740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII90_09745	COG1024	Enoyl-CoA hydratase
GII90_09750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII90_09755	COG0511	ligase activity, forming carbon-carbon bonds
GII90_09760	COG0439	Biotin carboxylase
GII90_09765	COG0318	PFAM AMP-dependent synthetase and ligase
GII90_09770	COG1960	acyl-CoA dehydrogenase activity
GII90_09785	COG1649	PFAM Uncharacterised BCR, COG1649
GII90_09795	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII90_09795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_09810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_09815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_09820	COG2027	D-alanyl-D-alanine carboxypeptidase
GII90_09825	COG2017	converts alpha-aldose to the beta-anomer
GII90_09830	COG0534	Mate efflux family protein
GII90_09845	COG0582	viral genome integration into host DNA
GII90_09850	COG0166	Belongs to the GPI family
GII90_09855	COG0405	Gamma-glutamyltransferase
GII90_09860	COG0583	DNA-binding transcription factor activity
GII90_09865	COG0604	alcohol dehydrogenase
GII90_09870	COG0493	'glutamate synthase
GII90_09875	COG0070	glutamate synthase
GII90_09875	COG0069	glutamate synthase activity
GII90_09875	COG0067	glutamate synthase
GII90_09880	COG0583	DNA-binding transcription factor activity
GII90_09885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII90_09890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII90_09900	COG0300	oxidoreductase activity
GII90_09905	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII90_09915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII90_09920	COG2814	Major facilitator Superfamily
GII90_09925	COG1070	Carbohydrate kinase
GII90_09930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII90_09935	COG0243	molybdopterin cofactor binding
GII90_09965	COG5278	phosphoserine phosphatase activity
GII90_09965	COG0840	transmembrane signaling receptor activity
GII90_09970	COG2368	4-hydroxyphenylacetate
GII90_09975	COG4305	rare lipoprotein A
GII90_09980	COG3619	membrane
GII90_09985	COG3866	Pectate lyase
GII90_09990	COG2135	peptidase activity
GII90_10000	COG2140	Oxalate decarboxylase
GII90_10015	COG0456	acetyltransferase
GII90_10035	COG2720	vancomycin resistance protein
GII90_10045	COG3655	Transcriptional regulator
GII90_10050	COG3739	integral membrane protein
GII90_10055	COG0583	DNA-binding transcription factor activity
GII90_10060	COG0697	spore germination
GII90_10070	COG0693	protein deglycase activity
GII90_10075	COG2367	Beta-lactamase
GII90_10100	COG0574	Belongs to the PEP-utilizing enzyme family
GII90_10100	COG3848	Pyruvate phosphate dikinase
GII90_10105	COG0726	polysaccharide deacetylase
GII90_10110	COG2314	TM2 domain
GII90_10115	COG1396	sequence-specific DNA binding
GII90_10130	COG2135	peptidase activity
GII90_10165	COG0457	Tetratricopeptide repeat
GII90_10190	COG5290	Psort location Cytoplasmic, score
GII90_10215	COG5444	nuclease activity
GII90_10220	COG4282	regulation of fungal-type cell wall biogenesis
GII90_10225	COG1231	oxidoreductase activity
GII90_10230	COG5434	Belongs to the glycosyl hydrolase 28 family
GII90_10235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII90_10240	COG0662	Cupin 2, conserved barrel domain protein
GII90_10240	COG2207	Transcriptional regulator
GII90_10245	COG0456	acetyltransferase
GII90_10250	COG1309	transcriptional regulator
GII90_10255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII90_10260	COG3708	Transcriptional regulator
GII90_10265	COG2378	regulation of single-species biofilm formation
GII90_10275	COG0640	Transcriptional regulator
GII90_10280	COG0741	lytic transglycosylase activity
GII90_10285	COG2322	membrane
GII90_10300	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII90_10305	COG3239	Fatty acid desaturase
GII90_10310	COG4585	Histidine kinase
GII90_10315	COG2197	response regulator
GII90_10320	COG1388	LysM domain
GII90_10320	COG3584	3D domain protein
GII90_10325	COG0514	ATP-dependent DNA helicase (RecQ)
GII90_10335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII90_10340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII90_10355	COG0071	Belongs to the small heat shock protein (HSP20) family
GII90_10380	COG1012	belongs to the aldehyde dehydrogenase family
GII90_10385	COG1657	PFAM Prenyltransferase squalene oxidase
GII90_10390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII90_10395	COG0733	neurotransmitter:sodium symporter activity
GII90_10400	COG0385	Bile acid
GII90_10405	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII90_10410	COG0567	Dehydrogenase, E1 component
GII90_10415	COG4548	von Willebrand factor, type A
GII90_10420	COG0714	Associated with various cellular activities
GII90_10425	COG2032	superoxide dismutase activity
GII90_10430	COG0791	NLP P60 protein
GII90_10430	COG1388	LysM domain
GII90_10435	COG1819	glycosyl
GII90_10440	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII90_10445	COG0534	Mate efflux family protein
GII90_10450	COG1366	Belongs to the anti-sigma-factor antagonist family
GII90_10455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII90_10460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII90_10470	COG2962	Rard protein
GII90_10485	COG2610	gluconate transmembrane transporter activity
GII90_10490	COG1942	4-Oxalocrotonate Tautomerase
GII90_10495	COG1733	regulation of RNA biosynthetic process
GII90_10500	COG0778	Nitroreductase
GII90_10505	COG0400	carboxylic ester hydrolase activity
GII90_10510	COG0346	lactoylglutathione lyase activity
GII90_10520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII90_10525	COG3409	Peptidoglycan-binding domain 1 protein
GII90_10525	COG0793	Belongs to the peptidase S41A family
GII90_10530	COG2226	methyltransferase
GII90_10540	COG1876	peptidase activity
GII90_10545	COG0813	purine-nucleoside phosphorylase activity
GII90_10560	COG0671	phosphoesterase, PA-phosphatase related
GII90_10580	COG4479	Belongs to the UPF0346 family
GII90_10590	COG1509	lysine 2,3-aminomutase activity
GII90_10595	COG0456	acetyltransferase
GII90_10600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII90_10605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII90_10610	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII90_10615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII90_10630	COG0456	acetyltransferase
GII90_10635	COG0463	Glycosyl transferase, family 2
GII90_10650	COG4641	Protein conserved in bacteria
GII90_10655	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII90_10660	COG1086	Polysaccharide biosynthesis protein
GII90_10665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII90_10670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII90_10675	COG1846	Transcriptional regulator
GII90_10680	COG0534	Mate efflux family protein
GII90_10690	COG4698	Protein conserved in bacteria
GII90_10695	COG2755	lipolytic protein G-D-S-L family
GII90_10700	COG1999	signal sequence binding
GII90_10710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII90_10715	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII90_10720	COG1272	protein, Hemolysin III
GII90_10725	COG0204	Acyl-transferase
GII90_10730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII90_10735	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII90_10740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII90_10750	COG2136	Putative SAM-dependent methyltransferase
GII90_10750	COG2521	methyltransferase
GII90_10760	COG0129	dihydroxy-acid dehydratase activity
GII90_10765	COG1413	lyase activity
GII90_10770	COG1418	mRNA catabolic process
GII90_10775	COG0386	Belongs to the glutathione peroxidase family
GII90_10780	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII90_10785	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII90_10795	COG1278	Cold shock
GII90_10815	COG0328	RNA-DNA hybrid ribonuclease activity
GII90_10820	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII90_10825	COG0328	RNA-DNA hybrid ribonuclease activity
GII90_10835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII90_10850	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII90_10860	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII90_10865	COG3424	synthase
GII90_10870	COG2233	PERMEase
GII90_10875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII90_10880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII90_10890	COG0800	Aldolase
GII90_10895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII90_10900	COG1609	Transcriptional regulator
GII90_10905	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII90_10910	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_10915	COG1199	ATP-dependent helicase activity
GII90_10930	COG0116	Belongs to the methyltransferase superfamily
GII90_10945	COG4474	Belongs to the UPF0398 family
GII90_10960	COG3359	exonuclease
GII90_10965	COG1205	dead DEAH box helicase
GII90_10965	COG1111	helicase
GII90_10970	COG2190	(PTS) system
GII90_10975	COG0071	Belongs to the small heat shock protein (HSP20) family
GII90_11010	COG3331	DNA recombination
GII90_11015	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII90_11015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII90_11025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII90_11030	COG3935	DnaD domain protein
GII90_11035	COG0017	Asparaginyl-tRNA synthetase
GII90_11040	COG0436	Aminotransferase
GII90_11045	COG5353	protein conserved in bacteria
GII90_11055	COG1199	ATP-dependent helicase activity
GII90_11055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII90_11060	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII90_11065	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII90_11070	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII90_11075	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII90_11075	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII90_11080	COG0617	tRNA 3'-terminal CCA addition
GII90_11085	COG0438	transferase activity, transferring glycosyl groups
GII90_11090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII90_11095	COG1803	Methylglyoxal synthase
GII90_11100	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII90_11105	COG1694	Mazg nucleotide pyrophosphohydrolase
GII90_11110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII90_11120	COG4347	Protein of unknown function (DUF1405)
GII90_11125	COG2010	Cytochrome c
GII90_11125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII90_11130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII90_11135	COG0723	plastoquinol--plastocyanin reductase activity
GII90_11145	COG5582	Belongs to the UPF0302 family
GII90_11150	COG0457	Tetratricopeptide repeat
GII90_11155	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII90_11160	COG0287	Prephenate dehydrogenase
GII90_11165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GII90_11170	COG0159	tryptophan synthase activity
GII90_11175	COG0133	tryptophan synthase activity
GII90_11180	COG0135	phosphoribosylanthranilate isomerase activity
GII90_11190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII90_11195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII90_11200	COG4401	Chorismate mutase type I
GII90_11205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII90_11210	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII90_11215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII90_11220	COG0105	UTP biosynthetic process
GII90_11225	COG0142	geranyltranstransferase activity
GII90_11230	COG2226	methyltransferase
GII90_11235	COG0142	geranyltranstransferase activity
GII90_11245	COG0302	gtp cyclohydrolase
GII90_11250	COG0776	regulation of translation
GII90_11255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII90_11270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII90_11275	COG1160	GTP binding
GII90_11300	COG1304	FMN binding
GII90_11305	COG0539	negative regulation of cytoplasmic translation
GII90_11310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII90_11320	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII90_11325	COG2959	enzyme of heme biosynthesis
GII90_11330	COG3773	Cell wall hydrolase
GII90_11330	COG3409	Peptidoglycan-binding domain 1 protein
GII90_11335	COG2339	peptidase activity
GII90_11340	COG0492	ferredoxin-NADP+ reductase activity
GII90_11345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII90_11350	COG4862	establishment of competence for transformation
GII90_11355	COG1408	metallophosphoesterase
GII90_11365	COG1388	LysM domain
GII90_11370	COG1266	CAAX protease self-immunity
GII90_11375	COG0514	ATP-dependent DNA helicase (RecQ)
GII90_11380	COG4955	Helix-turn-helix domain
GII90_11385	COG1141	Ferredoxin
GII90_11390	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII90_11395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII90_11400	COG0710	3-dehydroquinate dehydratase activity
GII90_11410	COG1595	DNA-templated transcription, initiation
GII90_11415	COG5002	protein histidine kinase activity
GII90_11420	COG0745	RESPONSE REGULATOR receiver
GII90_11425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII90_11430	COG1333	cytochrome c biogenesis protein
GII90_11435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII90_11440	COG1187	pseudouridine synthase activity
GII90_11445	COG0700	Nucleoside recognition
GII90_11450	COG2715	membrane protein required for spore maturation
GII90_11455	COG1686	Belongs to the peptidase S11 family
GII90_11465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII90_11470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII90_11475	COG1547	Domain of unknown function (DUF309)
GII90_11480	COG0456	acetyltransferase
GII90_11485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII90_11490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII90_11490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII90_11495	COG0307	riboflavin synthase, alpha
GII90_11500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII90_11500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII90_11510	COG0681	Belongs to the peptidase S26 family
GII90_11520	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII90_11535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII90_11540	COG4086	secreted protein
GII90_11545	COG0019	diaminopimelate decarboxylase activity
GII90_11550	COG0697	spore germination
GII90_11565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII90_11585	COG1191	sigma factor activity
GII90_11590	COG2172	sigma factor antagonist activity
GII90_11595	COG1366	Belongs to the anti-sigma-factor antagonist family
GII90_11600	COG1686	Belongs to the peptidase S11 family
GII90_11605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII90_11610	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII90_11615	COG4974	Belongs to the 'phage' integrase family
GII90_11625	COG0735	belongs to the Fur family
GII90_11630	COG1300	Membrane
GII90_11640	COG0281	malic enzyme
GII90_11645	COG1757	Na H antiporter
GII90_11650	COG1027	Aspartate ammonia-lyase
GII90_11655	COG0252	asparaginase activity
GII90_11660	COG1396	sequence-specific DNA binding
GII90_11665	COG1379	DNA repair
GII90_11670	COG0494	nUDIX hydrolase
GII90_11680	COG0667	Aldo Keto reductase
GII90_11690	COG1073	alpha beta
GII90_11700	COG4918	Iron-sulphur cluster biosynthesis
GII90_11705	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII90_11705	COG0456	acetyltransferase
GII90_11710	COG2329	Antibiotic biosynthesis monooxygenase
GII90_11715	COG0456	acetyltransferase
GII90_11725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII90_11735	COG2211	Major facilitator Superfamily
GII90_11740	COG0346	lactoylglutathione lyase activity
GII90_11745	COG1072	(Pantothenic acid kinase))
GII90_11750	COG3048	D-serine ammonia-lyase activity
GII90_11755	COG0300	oxidoreductase activity
GII90_11760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII90_11765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII90_11770	COG4187	Peptidase family M20/M25/M40
GII90_11775	COG1902	pentaerythritol trinitrate reductase activity
GII90_11780	COG0596	Alpha beta hydrolase
GII90_11790	COG1234	tRNA 3'-trailer cleavage
GII90_11795	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII90_11800	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII90_11805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII90_11815	COG0706	membrane insertase activity
GII90_11820	COG3361	conserved protein (COG2071)
GII90_11825	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII90_11830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII90_11835	COG0346	lactoylglutathione lyase activity
GII90_11845	COG1376	ErfK ybiS ycfS ynhG family protein
GII90_11850	COG4129	membrane
GII90_11855	COG1126	abc transporter atp-binding protein
GII90_11860	COG0765	amino acid transport
GII90_11865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII90_11875	COG1597	lipid kinase activity
GII90_11880	COG2814	Major facilitator Superfamily
GII90_11885	COG0789	Transcriptional regulator
GII90_11885	COG4978	Transcriptional regulator
GII90_11890	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII90_11895	COG0022	dehydrogenase e1 component
GII90_11900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII90_11905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII90_11910	COG3426	butyrate kinase activity
GII90_11915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII90_11920	COG0280	phosphate acetyltransferase
GII90_11925	COG3829	transcription factor binding
GII90_11925	COG3290	protein histidine kinase activity
GII90_11935	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII90_11940	COG2079	MmgE PrpD family protein
GII90_11945	COG0372	Belongs to the citrate synthase family
GII90_11950	COG1960	acyl-CoA dehydrogenase activity
GII90_11955	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII90_11960	COG0183	Belongs to the thiolase family
GII90_11965	COG0584	glycerophosphoryl diester phosphodiesterase
GII90_11970	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII90_11985	COG1902	pentaerythritol trinitrate reductase activity
GII90_11990	COG0745	RESPONSE REGULATOR receiver
GII90_11995	COG0750	zinc metalloprotease
GII90_12000	COG0497	DNA recombination
GII90_12005	COG1438	arginine binding
GII90_12010	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII90_12015	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII90_12020	COG0142	geranyltranstransferase activity
GII90_12025	COG1722	exodeoxyribonuclease VII activity
GII90_12030	COG1570	exodeoxyribonuclease VII activity
GII90_12035	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII90_12040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII90_12045	COG1302	Protein conserved in bacteria
GII90_12050	COG0439	Biotin carboxylase
GII90_12055	COG0511	ligase activity, forming carbon-carbon bonds
GII90_12095	COG3854	ATPases associated with a variety of cellular activities
GII90_12105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII90_12110	COG0006	proline dipeptidase activity
GII90_12115	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII90_12125	COG3872	metal-dependent enzyme
GII90_12135	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII90_12140	COG1321	iron dependent repressor
GII90_12145	COG0095	Lipoate-protein ligase
GII90_12150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII90_12155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII90_12160	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII90_12165	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII90_12170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII90_12185	COG1396	sequence-specific DNA binding
GII90_12195	COG0681	Belongs to the peptidase S26 family
GII90_12220	COG4940	Competence protein ComGF
GII90_12230	COG4970	Tfp pilus assembly protein FimT
GII90_12235	COG4537	Required for transformation and DNA binding
GII90_12240	COG1459	type II secretion system
GII90_12245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII90_12250	COG0598	Magnesium transport protein CorA
GII90_12255	COG1253	flavin adenine dinucleotide binding
GII90_12260	COG1366	Belongs to the anti-sigma-factor antagonist family
GII90_12270	COG1393	Belongs to the ArsC family
GII90_12280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII90_12290	COG0011	TIGRFAM Protein of
GII90_12300	COG2866	Carboxypeptidase
GII90_12305	COG1368	sulfuric ester hydrolase activity
GII90_12310	COG1940	carbohydrate kinase activity
GII90_12315	COG4483	Protein conserved in bacteria
GII90_12320	COG0457	Tetratricopeptide repeat
GII90_12320	COG0705	Rhomboid family
GII90_12330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII90_12335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GII90_12340	COG0438	transferase activity, transferring glycosyl groups
GII90_12355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII90_12360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII90_12365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII90_12370	COG0581	inorganic phosphate transmembrane transporter activity
GII90_12375	COG0573	inorganic phosphate transmembrane transporter activity
GII90_12380	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII90_12390	COG0477	Major facilitator Superfamily
GII90_12395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII90_12400	COG2839	Protein conserved in bacteria
GII90_12405	COG5521	maltodextrose utilization protein MalA
GII90_12415	COG1388	LysM domain
GII90_12420	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII90_12425	COG4709	membrane
GII90_12430	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII90_12435	COG0735	belongs to the Fur family
GII90_12440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII90_12450	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII90_12455	COG0513	Belongs to the DEAD box helicase family
GII90_12465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII90_12470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII90_12475	COG2384	SAM-dependent methyltransferase
GII90_12480	COG2010	Cytochrome c
GII90_12485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII90_12490	COG0358	DNA primase activity
GII90_12495	COG1671	Belongs to the UPF0178 family
GII90_12500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII90_12505	COG0517	IMP dehydrogenase activity
GII90_12510	COG0751	glycine-tRNA ligase activity
GII90_12515	COG0752	glycyl-tRNA synthetase alpha subunit
GII90_12520	COG1381	Involved in DNA repair and RecF pathway recombination
GII90_12530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII90_12535	COG0295	cytidine deaminase activity
GII90_12540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII90_12545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII90_12550	COG1480	7TM receptor with intracellular HD hydrolase
GII90_12555	COG1702	phosphate starvation-inducible protein PhoH
GII90_12560	COG0561	phosphatase activity
GII90_12575	COG4864	UPF0365 protein
GII90_12580	COG1030	water channel activity
GII90_12585	COG1610	YqeY-like protein
GII90_12590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GII90_12595	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII90_12600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII90_12605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII90_12610	COG2264	protein methyltransferase activity
GII90_12615	COG0484	heat shock protein binding
GII90_12620	COG0443	Heat shock 70 kDa protein
GII90_12625	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII90_12630	COG1420	regulation of RNA biosynthetic process
GII90_12635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII90_12640	COG0481	GTPase activity
GII90_12650	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII90_12655	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII90_12660	COG0268	Binds directly to 16S ribosomal RNA
GII90_12665	COG1466	dna polymerase III delta subunit
GII90_12680	COG2333	competence protein COMEC
GII90_12680	COG0658	competence protein
GII90_12685	COG2131	deaminase
GII90_12690	COG1596	polysaccharide export
GII90_12690	COG1555	photosystem II stabilization
GII90_12695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII90_12700	COG2226	methyltransferase
GII90_12705	COG0799	negative regulation of ribosome biogenesis
GII90_12710	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII90_12715	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII90_12720	COG1534	Rna-binding protein
GII90_12725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII90_12730	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII90_12735	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII90_12745	COG2755	lipolytic protein G-D-S-L family
GII90_12750	COG3409	Peptidoglycan-binding domain 1 protein
GII90_12750	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII90_12755	COG0398	Pfam SNARE associated Golgi protein
GII90_12760	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GII90_12770	COG3209	COG3209 Rhs family protein
GII90_12780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII90_12785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII90_12790	COG0798	PFAM Bile acid sodium symporter
GII90_12795	COG0346	lactoylglutathione lyase activity
GII90_12800	COG0640	Transcriptional regulator
GII90_12805	COG3403	YqcI/YcgG family
GII90_12810	COG0457	Tetratricopeptide repeat
GII90_12825	COG5444	nuclease activity
GII90_12850	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII90_12850	COG3409	Peptidoglycan-binding domain 1 protein
GII90_12855	COG4824	toxin secretion phage lysis holin
GII90_12885	COG3778	Protein conserved in bacteria
GII90_12890	COG3299	homolog of phage Mu protein gp47
GII90_12895	COG3628	GPW Gp25 family protein
GII90_12905	COG4193	domain, Protein
GII90_12915	COG1652	LysM domain
GII90_12920	COG3953	SLT domain
GII90_12920	COG5280	Phage tail tape measure protein TP901
GII90_12980	COG4653	Phage capsid family
GII90_12985	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII90_12995	COG2369	cell adhesion
GII90_13000	COG5518	Phage portal protein
GII90_13005	COG1783	phage Terminase large subunit
GII90_13010	COG5484	DNA packaging
GII90_13020	COG1335	isochorismatase
GII90_13055	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GII90_13065	COG1484	DNA-dependent DNA replication
GII90_13070	COG3935	DnaD domain protein
GII90_13075	COG3723	Recombinational DNA repair protein, rece pathway
GII90_13080	COG5377	YqaJ viral recombinase family
GII90_13110	COG1476	TRANSCRIPTIONal
GII90_13115	COG3620	sequence-specific DNA binding
GII90_13125	COG0563	adenylate kinase activity
GII90_13130	COG2856	Zn peptidase
GII90_13155	COG3223	Belongs to the PsiE family
GII90_13160	COG5002	protein histidine kinase activity
GII90_13160	COG0642	Histidine kinase
GII90_13165	COG0745	RESPONSE REGULATOR receiver
GII90_13170	COG2311	Membrane
GII90_13180	COG0454	-acetyltransferase
GII90_13185	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII90_13195	COG0730	response to heat
GII90_13200	COG0425	Belongs to the sulfur carrier protein TusA family
GII90_13205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII90_13205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII90_13215	COG0425	Belongs to the sulfur carrier protein TusA family
GII90_13215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII90_13225	COG2210	Belongs to the sulfur carrier protein TusA family
GII90_13230	COG1937	Protein conserved in bacteria
GII90_13240	COG0662	Cupin 2, conserved barrel domain protein
GII90_13250	COG0789	Transcriptional regulator
GII90_13250	COG4978	Transcriptional regulator
GII90_13255	COG2814	Major facilitator Superfamily
GII90_13260	COG0456	acetyltransferase
GII90_13265	COG1253	flavin adenine dinucleotide binding
GII90_13275	COG0697	spore germination
GII90_13280	COG0583	DNA-binding transcription factor activity
GII90_13285	COG2072	flavoprotein involved in K transport
GII90_13290	COG1230	cation diffusion facilitator family transporter
GII90_13295	COG1942	4-Oxalocrotonate Tautomerase
GII90_13300	COG0583	DNA-binding transcription factor activity
GII90_13310	COG1114	Component of the transport system for branched-chain amino acids
GII90_13315	COG1687	branched-chain amino acid
GII90_13320	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII90_13325	COG1522	sequence-specific DNA binding
GII90_13330	COG2732	(Barnase) inhibitor
GII90_13335	COG2124	cytochrome p450
GII90_13345	COG1335	isochorismatase
GII90_13355	COG2318	DinB family
GII90_13365	COG2070	2-Nitropropane dioxygenase
GII90_13370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII90_13390	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII90_13395	COG1595	DNA-templated transcription, initiation
GII90_13400	COG0667	Aldo Keto reductase
GII90_13405	COG2851	Citrate transporter
GII90_13410	COG0583	DNA-binding transcription factor activity
GII90_13415	COG2828	Protein conserved in bacteria
GII90_13420	COG3409	Peptidoglycan-binding domain 1 protein
GII90_13425	COG5566	PFAM Mor transcription activator
GII90_13430	COG0596	Alpha beta hydrolase
GII90_13435	COG4991	sh3 domain protein
GII90_13440	COG4991	sh3 domain protein
GII90_13450	COG0346	lactoylglutathione lyase activity
GII90_13460	COG5577	PFAM Coat F domain
GII90_13465	COG1063	alcohol dehydrogenase
GII90_13475	COG5577	PFAM Coat F domain
GII90_13480	COG0789	Transcriptional regulator
GII90_13490	COG1064	alcohol dehydrogenase
GII90_13495	COG0693	protein deglycase activity
GII90_13500	COG1621	beta-fructofuranosidase activity
GII90_13505	COG3716	PTS system mannose fructose sorbose family IID component
GII90_13510	COG3715	PTS system
GII90_13515	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_13520	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII90_13525	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII90_13525	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII90_13535	COG1113	amino acid transport
GII90_13540	COG1280	lysine exporter protein (LysE YggA)
GII90_13545	COG1378	Sugar-specific transcriptional regulator TrmB
GII90_13550	COG1595	DNA-templated transcription, initiation
GII90_13560	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GII90_13560	COG2755	lipolytic protein G-D-S-L family
GII90_13570	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII90_13570	COG2124	cytochrome p450
GII90_13575	COG1309	transcriptional regulator
GII90_13580	COG2226	methyltransferase
GII90_13595	COG2116	formate transmembrane transporter activity
GII90_13600	COG5609	conserved protein (DUF2294)
GII90_13605	COG3383	formate dehydrogenase (NAD+) activity
GII90_13610	COG2427	Protein of unknown function (DUF1641)
GII90_13620	COG0626	cystathionine gamma-synthase activity
GII90_13625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII90_13630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII90_13635	COG2226	methyltransferase
GII90_13650	COG0768	penicillin binding
GII90_13655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII90_13660	COG0572	uridine kinase
GII90_13680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII90_13685	COG3906	Belongs to the UPF0473 family
GII90_13690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII90_13695	COG4472	Bacterial protein of unknown function (DUF965)
GII90_13700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII90_13705	COG0628	permease
GII90_13710	COG1126	abc transporter atp-binding protein
GII90_13715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII90_13720	COG0765	amino acid transport
GII90_13725	COG0765	amino acid transport
GII90_13740	COG3881	PFAM PRC-barrel domain
GII90_13745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII90_13750	COG0457	Tetratricopeptide repeat
GII90_13755	COG0482	sulfurtransferase activity
GII90_13760	COG1104	cysteine desulfurase activity
GII90_13765	COG1959	2 iron, 2 sulfur cluster binding
GII90_13770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII90_13775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII90_13785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII90_13790	COG0124	histidyl-tRNA synthetase
GII90_13800	COG4991	sh3 domain protein
GII90_13800	COG3103	Sh3 type 3 domain protein
GII90_13800	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII90_13805	COG1490	D-aminoacyl-tRNA deacylase activity
GII90_13810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII90_13815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII90_13820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII90_13820	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII90_13825	COG5416	Lipopolysaccharide assembly protein A domain
GII90_13830	COG0490	domain, Protein
GII90_13835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII90_13835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII90_13845	COG2244	polysaccharide biosynthetic process
GII90_13850	COG2323	membrane
GII90_13860	COG1862	Preprotein translocase
GII90_13865	COG0343	queuine tRNA-ribosyltransferase activity
GII90_13870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII90_13880	COG2255	four-way junction helicase activity
GII90_13885	COG0632	four-way junction helicase activity
GII90_13895	COG2814	Major facilitator Superfamily
GII90_13900	COG0673	inositol 2-dehydrogenase activity
GII90_13905	COG2112	serine threonine protein kinase
GII90_13925	COG1115	amino acid carrier protein
GII90_13930	COG0217	transcriptional regulatory protein
GII90_13940	COG1388	LysM domain
GII90_13945	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII90_13950	COG0157	Belongs to the NadC ModD family
GII90_13955	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII90_13960	COG1104	cysteine desulfurase activity
GII90_13965	COG1827	regulation of RNA biosynthetic process
GII90_13970	COG0077	Prephenate dehydratase
GII90_13975	COG4492	Belongs to the UPF0735 family
GII90_13980	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII90_13985	COG3290	protein histidine kinase activity
GII90_13995	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII90_14000	COG2868	ribosomal protein
GII90_14005	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII90_14010	COG1994	Peptidase M50
GII90_14015	COG0739	heme binding
GII90_14020	COG2894	cell division
GII90_14025	COG0850	regulation of cytokinetic process
GII90_14030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII90_14035	COG1792	Involved in formation and maintenance of cell shape
GII90_14040	COG1077	Cell shape determining protein MreB Mrl
GII90_14045	COG2003	Belongs to the UPF0758 family
GII90_14050	COG0424	maF-like protein
GII90_14060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII90_14065	COG0285	dihydrofolate synthase activity
GII90_14070	COG0525	valine-tRNA ligase activity
GII90_14080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII90_14085	COG1388	LysM domain
GII90_14090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII90_14095	COG0113	porphobilinogen synthase activity
GII90_14100	COG1587	Uroporphyrinogen-III synthase
GII90_14105	COG0181	hydroxymethylbilane synthase activity
GII90_14110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII90_14115	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII90_14125	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII90_14130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII90_14135	COG1067	ATP-dependent peptidase activity
GII90_14135	COG0470	DNA polymerase III
GII90_14140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII90_14145	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII90_14150	COG0457	Tetratricopeptide repeat
GII90_14150	COG1477	protein flavinylation
GII90_14155	COG0066	3-isopropylmalate dehydratase activity
GII90_14160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII90_14165	COG0473	3-isopropylmalate dehydrogenase activity
GII90_14170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII90_14175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII90_14180	COG0440	acetolactate synthase activity
GII90_14185	COG0028	Belongs to the TPP enzyme family
GII90_14195	COG0454	-acetyltransferase
GII90_14200	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII90_14210	COG0622	Phosphoesterase
GII90_14215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII90_14220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII90_14225	COG5401	PFAM Sporulation and spore germination
GII90_14230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII90_14235	COG1846	Transcriptional regulator
GII90_14240	COG2197	response regulator
GII90_14245	COG0824	Thioesterase
GII90_14250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII90_14255	COG1053	succinate dehydrogenase
GII90_14260	COG2009	succinate dehydrogenase
GII90_14265	COG1719	4-vinyl reductase, 4VR
GII90_14270	COG0527	aspartate kinase activity
GII90_14275	COG0322	excinuclease ABC activity
GII90_14280	COG3118	belongs to the thioredoxin family
GII90_14290	COG3534	alpha-L-arabinofuranosidase
GII90_14295	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII90_14300	COG2086	electron transfer activity
GII90_14305	COG1024	Enoyl-CoA hydratase
GII90_14310	COG1309	transcriptional regulator
GII90_14315	COG0318	PFAM AMP-dependent synthetase and ligase
GII90_14320	COG3766	membrane
GII90_14325	COG1193	negative regulation of DNA recombination
GII90_14330	COG1796	DNA polymerase
GII90_14330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII90_14335	COG1286	toxin biosynthetic process
GII90_14340	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII90_14345	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII90_14350	COG0072	phenylalanine-tRNA ligase activity
GII90_14350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII90_14355	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII90_14365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII90_14375	COG3835	regulator
GII90_14380	COG0277	FAD linked oxidase domain protein
GII90_14385	COG0247	lactate metabolic process
GII90_14390	COG0346	lactoylglutathione lyase activity
GII90_14400	COG1966	Carbon starvation protein
GII90_14405	COG3534	alpha-L-arabinofuranosidase
GII90_14410	COG0395	ABC-type sugar transport system, permease component
GII90_14415	COG1175	transmembrane transport
GII90_14420	COG1653	transport
GII90_14425	COG0371	Dehydrogenase
GII90_14430	COG0647	UMP catabolic process
GII90_14435	COG0235	Class ii aldolase
GII90_14440	COG1069	ribulokinase activity
GII90_14445	COG2160	L-arabinose isomerase activity
GII90_14450	COG3507	Belongs to the glycosyl hydrolase 43 family
GII90_14455	COG1363	Peptidase, m42
GII90_14465	COG3326	Membrane
GII90_14470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII90_14475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII90_14480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII90_14490	COG1346	cytolysis
GII90_14495	COG1380	Effector of murein hydrolase LrgA
GII90_14500	COG3279	Response regulator of the LytR AlgR family
GII90_14505	COG3275	phosphorelay sensor kinase activity
GII90_14515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII90_14525	COG0398	Pfam SNARE associated Golgi protein
GII90_14530	COG1484	DNA-dependent DNA replication
GII90_14535	COG3611	Membrane attachment protein
GII90_14540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII90_14545	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII90_14550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII90_14555	COG1733	regulation of RNA biosynthetic process
GII90_14560	COG2814	Major facilitator Superfamily
GII90_14565	COG0656	L-ascorbic acid biosynthetic process
GII90_14570	COG0237	dephospho-CoA kinase activity
GII90_14575	COG1971	Probably functions as a manganese efflux pump
GII90_14580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII90_14585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII90_14585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII90_14590	COG5002	protein histidine kinase activity
GII90_14595	COG0745	RESPONSE REGULATOR receiver
GII90_14600	COG0039	L-malate dehydrogenase activity
GII90_14605	COG0538	isocitrate dehydrogenase activity
GII90_14610	COG0372	Belongs to the citrate synthase family
GII90_14615	COG2707	UPF0756 membrane protein
GII90_14620	COG0628	permease
GII90_14625	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII90_14630	COG0469	pyruvate kinase activity
GII90_14635	COG0205	6-phosphofructokinase activity
GII90_14640	COG0825	malonyl-CoA metabolic process
GII90_14645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII90_14650	COG0281	malic enzyme
GII90_14655	COG0587	DNA-directed DNA polymerase activity
GII90_14675	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII90_14685	COG4109	DRTGG domain
GII90_14690	COG0730	response to heat
GII90_14695	COG1473	amidohydrolase
GII90_14700	COG0196	riboflavin kinase activity
GII90_14705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII90_14710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII90_14715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII90_14720	COG1126	abc transporter atp-binding protein
GII90_14725	COG0765	amino acid transport
GII90_14730	COG0765	amino acid transport
GII90_14735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII90_14740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII90_14745	COG0454	-acetyltransferase
GII90_14750	COG0583	DNA-binding transcription factor activity
GII90_14755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII90_14760	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_14770	COG0165	Argininosuccinate lyase
GII90_14775	COG0137	argininosuccinate synthase activity
GII90_14780	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII90_14785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII90_14795	COG0827	DNA restriction-modification system
GII90_14800	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII90_14805	COG3874	Sporulation protein YtfJ
GII90_14815	COG1714	RDD family
GII90_14820	COG0616	signal peptide processing
GII90_14825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII90_14830	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII90_14835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII90_14845	COG0301	tRNA thio-modification
GII90_14850	COG1104	cysteine desulfurase activity
GII90_14855	COG1114	Component of the transport system for branched-chain amino acids
GII90_14860	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII90_14865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII90_14870	COG1309	transcriptional regulator
GII90_14875	COG1956	GAF domain-containing protein
GII90_14880	COG2203	Gaf domain
GII90_14880	COG2199	diguanylate cyclase activity
GII90_14890	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII90_14895	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII90_14900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII90_14905	COG0454	-acetyltransferase
GII90_14910	COG0517	IMP dehydrogenase activity
GII90_14915	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII90_14920	COG1360	Flagellar Motor Protein
GII90_14925	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII90_14930	COG1609	Transcriptional regulator
GII90_14935	COG1605	Chorismate mutase
GII90_14935	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII90_14940	COG3118	belongs to the thioredoxin family
GII90_14945	COG4980	gas vesicle protein
GII90_14950	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII90_14955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII90_14960	COG1674	ftsk spoiiie
GII90_14965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII90_14970	COG4848	Belongs to the UPF0354 family
GII90_14975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII90_14990	COG1363	Peptidase, m42
GII90_14995	COG5584	Small secreted protein
GII90_15000	COG0281	malic enzyme
GII90_15005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII90_15010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII90_15020	COG0510	thiamine kinase activity
GII90_15025	COG1523	belongs to the glycosyl hydrolase 13 family
GII90_15030	COG1597	lipid kinase activity
GII90_15040	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII90_15045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII90_15050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII90_15055	COG2252	PERMEase
GII90_15060	COG4473	ABC transporter
GII90_15065	COG1131	(ABC) transporter
GII90_15070	COG1349	DNA-binding transcription factor activity
GII90_15075	COG1187	pseudouridine synthase activity
GII90_15080	COG2244	polysaccharide biosynthetic process
GII90_15085	COG2081	HI0933 family
GII90_15090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII90_15100	COG5578	integral membrane protein
GII90_15105	COG0673	inositol 2-dehydrogenase activity
GII90_15110	COG1653	transport
GII90_15115	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII90_15120	COG4209	transmembrane transport
GII90_15125	COG2207	Transcriptional regulator
GII90_15130	COG1653	transport
GII90_15135	COG0395	ABC-type sugar transport system, permease component
GII90_15140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII90_15145	COG2124	cytochrome p450
GII90_15150	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII90_15155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GII90_15160	COG0156	8-amino-7-oxononanoate synthase activity
GII90_15165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII90_15170	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GII90_15175	COG1073	alpha beta
GII90_15200	COG1486	melibiose metabolic process
GII90_15205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII90_15210	COG0495	leucyl-tRNA aminoacylation
GII90_15220	COG2202	Pas domain
GII90_15220	COG1366	Belongs to the anti-sigma-factor antagonist family
GII90_15225	COG2814	Major facilitator Superfamily
GII90_15230	COG2433	Pfam Transposase IS66
GII90_15235	COG0577	efflux transmembrane transporter activity
GII90_15240	COG1136	(ABC) transporter
GII90_15245	COG2205	protein histidine kinase activity
GII90_15250	COG0745	RESPONSE REGULATOR receiver
GII90_15255	COG0577	efflux transmembrane transporter activity
GII90_15260	COG1136	(ABC) transporter
GII90_15275	COG1131	(ABC) transporter
GII90_15280	COG1725	Transcriptional regulator
GII90_15295	COG1242	4 iron, 4 sulfur cluster binding
GII90_15300	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII90_15310	COG2267	carboxylic ester hydrolase activity
GII90_15315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII90_15320	COG1113	amino acid transport
GII90_15325	COG0367	asparagine synthase
GII90_15330	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII90_15335	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII90_15345	COG1506	peptidase
GII90_15350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII90_15355	COG1116	anion transmembrane transporter activity
GII90_15360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII90_15365	COG0494	nUDIX hydrolase
GII90_15370	COG4824	toxin secretion phage lysis holin
GII90_15375	COG0783	Belongs to the Dps family
GII90_15390	COG1854	S-ribosylhomocysteine lyase activity
GII90_15395	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII90_15400	COG0288	reversible hydration of carbon dioxide
GII90_15405	COG0254	rRNA binding
GII90_15410	COG1271	oxidase subunit
GII90_15415	COG1294	oxidase, subunit
GII90_15425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII90_15430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII90_15430	COG1321	iron dependent repressor
GII90_15435	COG1121	(ABC) transporter
GII90_15440	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII90_15445	COG4948	Mandelate Racemase Muconate Lactonizing
GII90_15450	COG0318	PFAM AMP-dependent synthetase and ligase
GII90_15455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII90_15460	COG0596	Alpha beta hydrolase
GII90_15465	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII90_15470	COG1169	isochorismate synthase
GII90_15475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII90_15480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII90_15485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII90_15490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII90_15495	COG0438	transferase activity, transferring glycosyl groups
GII90_15505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII90_15510	COG0438	transferase activity, transferring glycosyl groups
GII90_15515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII90_15520	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GII90_15525	COG0058	SHG alpha-glucan phosphorylase activity
GII90_15530	COG0297	glycogen (starch) synthase activity
GII90_15535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII90_15540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII90_15545	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII90_15670	COG3859	Proton-coupled thiamine transporter YuaJ
GII90_15675	COG1247	-acetyltransferase
GII90_15680	COG2268	Band 7 protein
GII90_15685	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII90_15690	COG2318	DinB family
GII90_15700	COG1454	alcohol dehydrogenase
GII90_15710	COG1510	regulation of RNA biosynthetic process
GII90_15720	COG0569	domain protein
GII90_15725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII90_15730	COG4682	membrane
GII90_15735	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII90_15740	COG0477	Major facilitator Superfamily
GII90_15745	COG5553	Cysteine dioxygenase type I
GII90_15755	COG1968	undecaprenyl-diphosphatase activity
GII90_15760	COG0628	permease
GII90_15765	COG0673	inositol 2-dehydrogenase activity
GII90_15770	COG4806	L-rhamnose isomerase
GII90_15775	COG3254	rhamnose metabolic process
GII90_15780	COG1070	Carbohydrate kinase
GII90_15785	COG1349	DNA-binding transcription factor activity
GII90_15790	COG3347	Dehydrogenase
GII90_15790	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_15795	COG0840	transmembrane signaling receptor activity
GII90_15800	COG0840	transmembrane signaling receptor activity
GII90_15805	COG0840	transmembrane signaling receptor activity
GII90_15810	COG0840	transmembrane signaling receptor activity
GII90_15825	COG0432	Pfam Uncharacterised protein family UPF0047
GII90_15835	COG0366	Alpha amylase catalytic
GII90_15840	COG1253	flavin adenine dinucleotide binding
GII90_15845	COG2738	Putative neutral zinc metallopeptidase
GII90_15860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII90_15875	COG0166	Belongs to the GPI family
GII90_15880	COG1979	alcohol dehydrogenase
GII90_15885	COG1979	alcohol dehydrogenase
GII90_15890	COG2155	Conserved Protein
GII90_15895	COG1098	S1 RNA binding domain
GII90_15900	COG0436	Aminotransferase
GII90_15905	COG1522	sequence-specific DNA binding
GII90_15910	COG2267	carboxylic ester hydrolase activity
GII90_15920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII90_15925	COG2205	protein histidine kinase activity
GII90_15935	COG5018	Exonuclease
GII90_15945	COG2814	Major facilitator Superfamily
GII90_15950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII90_15955	COG3011	Protein conserved in bacteria
GII90_15965	COG3290	protein histidine kinase activity
GII90_15970	COG4565	transcriptional regulatory protein
GII90_15995	COG3493	citrate carrier protein
GII90_16005	COG2111	Na H antiporter
GII90_16005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII90_16010	COG2111	Na H antiporter
GII90_16015	COG1006	Multisubunit Na H antiporter MnhC subunit
GII90_16020	COG0651	ATP synthesis coupled electron transport
GII90_16025	COG1863	multisubunit Na H antiporter MnhE subunit
GII90_16030	COG2212	antiporter activity
GII90_16035	COG1320	monovalent cation:proton antiporter activity
GII90_16040	COG2050	protein possibly involved in aromatic compounds catabolism
GII90_16045	COG2197	response regulator
GII90_16050	COG4585	Histidine kinase
GII90_16060	COG0142	geranyltranstransferase activity
GII90_16080	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII90_16085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII90_16090	COG1335	isochorismatase
GII90_16095	COG5506	Protein of unknown function (DUF1694)
GII90_16110	COG0628	permease
GII90_16125	COG1418	mRNA catabolic process
GII90_16130	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_16140	COG1511	domain protein
GII90_16145	COG0433	COG0433 Predicted ATPase
GII90_16145	COG1674	ftsk spoiiie
GII90_16150	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII90_16155	COG5417	Belongs to the EsaB family
GII90_16160	COG4842	Belongs to the WXG100 family
GII90_16165	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII90_16165	COG2508	Transcriptional regulator
GII90_16170	COG0686	Belongs to the AlaDH PNT family
GII90_16175	COG5634	Uncharacterized conserved protein (DUF2278)
GII90_16180	COG3251	PFAM MbtH domain protein
GII90_16185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_16190	COG1535	isochorismatase
GII90_16190	COG3433	isochorismatase activity
GII90_16195	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII90_16200	COG1169	isochorismate synthase
GII90_16205	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_16210	COG2819	hydrolase of the alpha beta superfamily
GII90_16215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII90_16220	COG1268	BioY protein
GII90_16225	COG2056	Na+-H+ antiporter family
GII90_16230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII90_16235	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII90_16240	COG3584	3D domain protein
GII90_16255	COG1252	NADH dehydrogenase
GII90_16260	COG0492	ferredoxin-NADP+ reductase activity
GII90_16270	COG0516	GMP reductase activity
GII90_16275	COG2808	Putative FMN-binding domain
GII90_16280	COG0456	acetyltransferase
GII90_16285	COG0316	Belongs to the HesB IscA family
GII90_16290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII90_16295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII90_16300	COG4844	belongs to the
GII90_16305	COG1252	NADH dehydrogenase
GII90_16310	COG4837	Protein of unknown function (DUF1462)
GII90_16315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII90_16320	COG4946	Tricorn protease homolog
GII90_16320	COG1506	peptidase
GII90_16320	COG0823	Involved in the tonB-independent uptake of proteins
GII90_16325	COG0083	homoserine kinase activity
GII90_16330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII90_16335	COG0460	homoserine dehydrogenase
GII90_16340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII90_16345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII90_16350	COG0647	UMP catabolic process
GII90_16355	COG2445	Protein of unknown function DUF86
GII90_16360	COG4470	Protein conserved in bacteria
GII90_16370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII90_16375	COG0739	heme binding
GII90_16385	COG3377	Domain of unknown function (DUF1805)
GII90_16390	COG0737	Belongs to the 5'-nucleotidase family
GII90_16395	COG0730	response to heat
GII90_16400	COG1801	Protein of unknown function DUF72
GII90_16410	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII90_16415	COG2508	Transcriptional regulator
GII90_16420	COG2233	PERMEase
GII90_16425	COG2233	PERMEase
GII90_16430	COG3648	Uricase
GII90_16430	COG3195	allantoin biosynthetic process
GII90_16435	COG2351	hydroxyisourate hydrolase activity
GII90_16445	COG2080	2 iron, 2 sulfur cluster binding
GII90_16450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII90_16455	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII90_16460	COG2068	MobA-Related Protein
GII90_16465	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII90_16470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII90_16475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII90_16485	COG2356	endonuclease I
GII90_16490	COG3842	ATPase activity
GII90_16495	COG2188	Transcriptional regulator
GII90_16500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII90_16505	COG0395	ABC-type sugar transport system, permease component
GII90_16510	COG1175	transmembrane transport
GII90_16515	COG1653	transport
GII90_16520	COG2222	sugar isomerase
GII90_16525	COG0322	excinuclease ABC activity
GII90_16530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII90_16545	COG0346	lactoylglutathione lyase activity
GII90_16550	COG0640	Transcriptional regulator
GII90_16555	COG0719	Fe-S assembly protein
GII90_16560	COG0822	iron-sulfur transferase activity
GII90_16565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII90_16570	COG0719	Fe-S assembly protein
GII90_16575	COG0396	ATPase activity
GII90_16585	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII90_16590	COG1464	Belongs to the NlpA lipoprotein family
GII90_16595	COG2011	ABC-type metal ion transport system permease component
GII90_16600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII90_16610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII90_16615	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII90_16625	COG0509	glycine decarboxylation via glycine cleavage system
GII90_16630	COG1393	Belongs to the ArsC family
GII90_16635	COG1960	acyl-CoA dehydrogenase activity
GII90_16640	COG0183	Belongs to the thiolase family
GII90_16645	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII90_16645	COG1024	Enoyl-CoA hydratase
GII90_16655	COG0506	proline dehydrogenase activity
GII90_16665	COG5577	PFAM Coat F domain
GII90_16670	COG1846	Transcriptional regulator
GII90_16675	COG0477	Major facilitator Superfamily
GII90_16680	COG1942	4-Oxalocrotonate Tautomerase
GII90_16690	COG0583	DNA-binding transcription factor activity
GII90_16700	COG1120	ATPase activity
GII90_16715	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_16720	COG0783	Belongs to the Dps family
GII90_16725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII90_16730	COG0745	RESPONSE REGULATOR receiver
GII90_16735	COG2205	protein histidine kinase activity
GII90_16735	COG2770	Histidine kinase
GII90_16745	COG1309	transcriptional regulator
GII90_16750	COG0114	fumarate hydratase activity
GII90_16760	COG0697	spore germination
GII90_16765	COG0814	amino acid
GII90_16775	COG2197	response regulator
GII90_16780	COG4585	Histidine kinase
GII90_16785	COG4758	membrane
GII90_16790	COG3595	metallopeptidase activity
GII90_16795	COG1842	Phage shock protein A
GII90_16800	COG4758	membrane
GII90_16805	COG2814	Major facilitator Superfamily
GII90_16810	COG2096	Adenosyltransferase
GII90_16815	COG1120	ATPase activity
GII90_16820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII90_16825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII90_16830	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_16835	COG3386	PFAM SMP-30 Gluconolaconase
GII90_16840	COG2205	protein histidine kinase activity
GII90_16845	COG0745	RESPONSE REGULATOR receiver
GII90_16855	COG1191	sigma factor activity
GII90_16865	COG2140	Oxalate decarboxylase
GII90_16875	COG0577	efflux transmembrane transporter activity
GII90_16880	COG1136	(ABC) transporter
GII90_16885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII90_16890	COG1120	ATPase activity
GII90_16895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII90_16900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII90_16905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII90_16910	COG0531	amino acid
GII90_16920	COG1988	membrane-bound metal-dependent
GII90_16925	COG1368	sulfuric ester hydrolase activity
GII90_16930	COG1910	domain protein
GII90_16935	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII90_16940	COG4149	molybdate abc transporter
GII90_16945	COG0656	L-ascorbic acid biosynthetic process
GII90_16955	COG0025	NhaP-type Na H and K H
GII90_16960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII90_16965	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII90_16970	COG3973	AAA domain
GII90_16975	COG2860	membrane
GII90_16980	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII90_16985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII90_16990	COG2217	Heavy metal translocating P-type atpase
GII90_16995	COG2217	Heavy metal translocating P-type atpase
GII90_17000	COG2608	mercury ion transmembrane transporter activity
GII90_17005	COG1937	Protein conserved in bacteria
GII90_17010	COG0673	inositol 2-dehydrogenase activity
GII90_17015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII90_17020	COG1289	transmembrane transporter activity
GII90_17030	COG2076	Multidrug Resistance protein
GII90_17035	COG1309	transcriptional regulator
GII90_17040	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_17050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII90_17055	COG0557	exoribonuclease II activity
GII90_17060	COG1647	Serine aminopeptidase, S33
GII90_17065	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII90_17070	COG0596	Alpha beta hydrolase
GII90_17075	COG1476	TRANSCRIPTIONal
GII90_17080	COG1396	sequence-specific DNA binding
GII90_17085	COG1396	sequence-specific DNA binding
GII90_17090	COG1733	regulation of RNA biosynthetic process
GII90_17095	COG0840	transmembrane signaling receptor activity
GII90_17100	COG1174	glycine betaine transport
GII90_17105	COG1732	Glycine betaine
GII90_17110	COG1174	glycine betaine transport
GII90_17115	COG1125	glycine betaine transport
GII90_17115	COG0517	IMP dehydrogenase activity
GII90_17120	COG1510	regulation of RNA biosynthetic process
GII90_17140	COG5658	integral membrane protein
GII90_17145	COG0640	Transcriptional regulator
GII90_17150	COG1174	glycine betaine transport
GII90_17155	COG1732	Glycine betaine
GII90_17160	COG1174	glycine betaine transport
GII90_17165	COG0517	IMP dehydrogenase activity
GII90_17165	COG1125	glycine betaine transport
GII90_17170	COG1510	regulation of RNA biosynthetic process
GII90_17175	COG2095	MarC family integral membrane protein
GII90_17185	COG3064	Membrane
GII90_17190	COG4640	response to antibiotic
GII90_17195	COG0456	acetyltransferase
GII90_17200	COG0148	phosphopyruvate hydratase activity
GII90_17205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII90_17210	COG0149	triose-phosphate isomerase activity
GII90_17215	COG0126	phosphoglycerate kinase activity
GII90_17220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII90_17225	COG2390	Transcriptional regulator
GII90_17230	COG2814	Major facilitator Superfamily
GII90_17235	COG1609	Transcriptional regulator
GII90_17240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII90_17245	COG0583	DNA-binding transcription factor activity
GII90_17250	COG0697	spore germination
GII90_17255	COG1113	amino acid transport
GII90_17260	COG3858	chitin binding
GII90_17265	COG1556	Lactate utilization protein
GII90_17270	COG1139	Iron-sulfur cluster binding protein
GII90_17275	COG0247	lactate metabolic process
GII90_17280	COG2197	response regulator
GII90_17285	COG4585	Histidine kinase
GII90_17290	COG0842	Transport permease protein
GII90_17295	COG1131	(ABC) transporter
GII90_17300	COG0596	Alpha beta hydrolase
GII90_17305	COG2208	phosphoserine phosphatase activity
GII90_17310	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII90_17315	COG1874	Beta-galactosidase
GII90_17320	COG3833	ABC-type maltose transport systems, permease component
GII90_17325	COG1175	transmembrane transport
GII90_17330	COG2182	Extracellular solute-binding protein
GII90_17335	COG1609	Transcriptional regulator
GII90_17340	COG2186	Transcriptional regulator
GII90_17345	COG1620	l-lactate permease
GII90_17350	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII90_17360	COG5039	Polysaccharide pyruvyl transferase
GII90_17365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII90_17370	COG0110	maltose O-acetyltransferase activity
GII90_17375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII90_17380	COG2244	polysaccharide biosynthetic process
GII90_17385	COG1216	Glycosyl transferase, family 2
GII90_17390	COG5039	Polysaccharide pyruvyl transferase
GII90_17395	COG1216	Glycosyl transferase, family 2
GII90_17405	COG0438	transferase activity, transferring glycosyl groups
GII90_17410	COG1215	transferase activity, transferring glycosyl groups
GII90_17415	COG0438	transferase activity, transferring glycosyl groups
GII90_17420	COG1086	Polysaccharide biosynthesis protein
GII90_17425	COG0489	protein tyrosine kinase activity
GII90_17430	COG3944	biosynthesis protein
GII90_17435	COG1396	sequence-specific DNA binding
GII90_17440	COG2272	Belongs to the type-B carboxylesterase lipase family
GII90_17450	COG3479	Phenolic acid decarboxylase
GII90_17460	COG1794	racemase activity, acting on amino acids and derivatives
GII90_17465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII90_17470	COG1621	beta-fructofuranosidase activity
GII90_17475	COG1621	beta-fructofuranosidase activity
GII90_17480	COG0531	amino acid
GII90_17485	COG1309	transcriptional regulator
GII90_17490	COG2076	Multidrug Resistance protein
GII90_17495	COG2076	Multidrug Resistance protein
GII90_17505	COG0277	FAD linked oxidase domain protein
GII90_17510	COG3621	Patatin-like phospholipase
GII90_17520	COG0740	serine-type endopeptidase activity
GII90_17525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII90_17530	COG0366	Alpha amylase catalytic
GII90_17535	COG1554	hydrolase, family 65, central catalytic
GII90_17540	COG5521	maltodextrose utilization protein MalA
GII90_17545	COG3833	ABC-type maltose transport systems, permease component
GII90_17550	COG1175	transmembrane transport
GII90_17555	COG2182	Extracellular solute-binding protein
GII90_17560	COG0366	Alpha amylase catalytic
GII90_17565	COG1609	Transcriptional regulator
GII90_17570	COG1611	Belongs to the LOG family
GII90_17575	COG1694	Mazg nucleotide pyrophosphohydrolase
GII90_17580	COG0659	secondary active sulfate transmembrane transporter activity
GII90_17585	COG0288	reversible hydration of carbon dioxide
GII90_17590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII90_17595	COG0577	efflux transmembrane transporter activity
GII90_17600	COG1136	(ABC) transporter
GII90_17605	COG5002	protein histidine kinase activity
GII90_17610	COG0745	RESPONSE REGULATOR receiver
GII90_17620	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII90_17625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII90_17630	COG1481	regulation of sporulation
GII90_17635	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII90_17640	COG1660	Displays ATPase and GTPase activities
GII90_17645	COG1051	belongs to the nudix hydrolase family
GII90_17650	COG0492	ferredoxin-NADP+ reductase activity
GII90_17655	COG3883	PFAM NLP P60 protein
GII90_17655	COG0791	NLP P60 protein
GII90_17660	COG0457	Tetratricopeptide repeat
GII90_17665	COG1132	(ABC) transporter
GII90_17685	COG0140	phosphoribosyl-ATP diphosphatase activity
GII90_17685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII90_17690	COG0107	imidazoleglycerol-phosphate synthase activity
GII90_17695	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII90_17700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII90_17705	COG0131	Imidazoleglycerol-phosphate dehydratase
GII90_17710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII90_17715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII90_17720	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII90_17725	COG4990	cell redox homeostasis
GII90_17730	COG5297	Belongs to the glycosyl hydrolase family 6
GII90_17735	COG0110	maltose O-acetyltransferase activity
GII90_17740	COG0546	phosphoglycolate phosphatase activity
GII90_17745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII90_17750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII90_17755	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII90_17760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII90_17765	COG0363	glucosamine-6-phosphate deaminase activity
GII90_17775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII90_17780	COG1846	Transcriptional regulator
GII90_17785	COG2124	cytochrome p450
GII90_17795	COG1846	Transcriptional regulator
GII90_17800	COG2814	Major facilitator Superfamily
GII90_17805	COG1950	PFAM Membrane protein of
GII90_17810	COG1983	PspC domain protein
GII90_17815	COG3595	metallopeptidase activity
GII90_17835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII90_17840	COG0556	nucleotide-excision repair
GII90_17845	COG4897	Protein conserved in bacteria
GII90_17850	COG3848	Pyruvate phosphate dikinase
GII90_17850	COG0574	Belongs to the PEP-utilizing enzyme family
GII90_17855	COG1309	transcriptional regulator
GII90_17860	COG2814	Major facilitator Superfamily
GII90_17865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII90_17875	COG0793	Belongs to the peptidase S41A family
GII90_17875	COG3409	Peptidoglycan-binding domain 1 protein
GII90_17880	COG2177	Part of the ABC transporter FtsEX involved in
GII90_17885	COG2884	Cell division ATP-binding protein ftsE
GII90_17890	COG2010	Cytochrome c
GII90_17895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII90_17905	COG0653	protein targeting
GII90_17910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII90_17925	COG1516	flagellar protein fliS
GII90_17930	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII90_17935	COG1334	flagellar protein FlaG
GII90_17940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII90_17945	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII90_17950	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII90_17960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII90_17965	COG4786	Flagellar basal body rod
GII90_17965	COG1256	bacterial-type flagellum assembly
GII90_17970	COG3418	PFAM FlgN family protein
GII90_17975	COG2747	anti-sigma28 factor FlgM
GII90_17985	COG1040	competence protein
GII90_17995	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII90_18000	COG1307	EDD domain protein, DegV family
GII90_18005	COG2197	response regulator
GII90_18010	COG4585	Histidine kinase
GII90_18015	COG1739	Uncharacterized protein family UPF0029
GII90_18020	COG1316	TRANSCRIPTIONal
GII90_18025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII90_18030	COG0438	transferase activity, transferring glycosyl groups
GII90_18035	COG1215	transferase activity, transferring glycosyl groups
GII90_18040	COG3206	protein involved in exopolysaccharide biosynthesis
GII90_18045	COG3307	-O-antigen
GII90_18050	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII90_18055	COG0297	glycogen (starch) synthase activity
GII90_18055	COG0438	transferase activity, transferring glycosyl groups
GII90_18060	COG2244	polysaccharide biosynthetic process
GII90_18070	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII90_18070	COG2247	cell wall binding repeat
GII90_18075	COG2247	cell wall binding repeat
GII90_18075	COG2385	sporulation resulting in formation of a cellular spore
GII90_18085	COG1316	TRANSCRIPTIONal
GII90_18090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII90_18095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII90_18105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII90_18105	COG1215	transferase activity, transferring glycosyl groups
GII90_18110	COG0463	Glycosyl transferase, family 2
GII90_18120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII90_18130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII90_18135	COG1134	teichoic acid transport
GII90_18140	COG1682	transport, permease protein
GII90_18145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII90_18150	COG0438	transferase activity, transferring glycosyl groups
GII90_18155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GII90_18160	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GII90_18165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII90_18175	COG4193	domain, Protein
GII90_18180	COG1482	cell wall glycoprotein biosynthetic process
GII90_18185	COG0697	spore germination
GII90_18190	COG0814	amino acid
GII90_18200	COG2814	Major facilitator Superfamily
GII90_18205	COG1316	TRANSCRIPTIONal
GII90_18210	COG0561	phosphatase activity
GII90_18215	COG0791	NLP P60 protein
GII90_18225	COG2843	Capsule synthesis protein
GII90_18235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII90_18240	COG1609	Transcriptional regulator
GII90_18245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII90_18250	COG1869	D-ribose catabolic process
GII90_18260	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII90_18265	COG1879	ABC-type sugar transport system periplasmic component
GII90_18270	COG3103	Sh3 type 3 domain protein
GII90_18280	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII90_18285	COG3527	Alpha-acetolactate decarboxylase
GII90_18290	COG0028	Belongs to the TPP enzyme family
GII90_18295	COG0583	DNA-binding transcription factor activity
GII90_18300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII90_18315	COG5337	Spore coat protein CotH
GII90_18325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII90_18335	COG0405	Gamma-glutamyltransferase
GII90_18340	COG1522	sequence-specific DNA binding
GII90_18345	COG2059	Chromate
GII90_18350	COG2059	Chromate
GII90_18360	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII90_18365	COG0583	DNA-binding transcription factor activity
GII90_18370	COG1515	deoxyribonuclease V activity
GII90_18375	COG2849	repeat protein
GII90_18380	COG5444	nuclease activity
GII90_18400	COG3878	Protein conserved in bacteria
GII90_18405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII90_18410	COG4464	protein tyrosine phosphatase activity
GII90_18415	COG0489	protein tyrosine kinase activity
GII90_18420	COG3944	biosynthesis protein
GII90_18430	COG4715	Zinc finger, swim domain protein
GII90_18435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII90_18440	COG0561	phosphatase activity
GII90_18445	COG1349	DNA-binding transcription factor activity
GII90_18450	COG0629	single-stranded DNA binding
GII90_18465	COG3764	Sortase (surface protein transpeptidase)
GII90_18475	COG2972	Histidine kinase
GII90_18475	COG0745	RESPONSE REGULATOR receiver
GII90_18480	COG1970	mechanosensitive ion channel activity
GII90_18485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII90_18490	COG0457	Tetratricopeptide repeat
GII90_18495	COG4786	Flagellar basal body rod
GII90_18500	COG4786	Flagellar basal body rod
GII90_18505	COG1077	Cell shape determining protein MreB Mrl
GII90_18510	COG1609	Transcriptional regulator
GII90_18520	COG1846	Transcriptional regulator
GII90_18525	COG2814	Major facilitator Superfamily
GII90_18530	COG3420	alginic acid biosynthetic process
GII90_18535	COG1953	Uracil, thiamine, allantoin
GII90_18540	COG0477	Major facilitator Superfamily
GII90_18545	COG1335	isochorismatase
GII90_18555	COG0004	ammonium transporteR
GII90_18560	COG0347	Belongs to the P(II) protein family
GII90_18565	COG0671	phosphoesterase, PA-phosphatase related
GII90_18575	COG0739	heme binding
GII90_18580	COG1247	-acetyltransferase
GII90_18600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII90_18605	COG0789	Transcriptional regulator
GII90_18615	COG2910	NAD(P)H-binding
GII90_18620	COG1959	2 iron, 2 sulfur cluster binding
GII90_18625	COG0804	urea catabolic process
GII90_18630	COG0832	Belongs to the urease beta subunit family
GII90_18635	COG0831	urea catabolic process
GII90_18650	COG3237	CsbD-like
GII90_18655	COG1994	Peptidase M50
GII90_18660	COG0457	Tetratricopeptide repeat
GII90_18665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII90_18670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII90_18680	COG2304	oxidoreductase activity
GII90_18690	COG2304	oxidoreductase activity
GII90_18695	COG2385	sporulation resulting in formation of a cellular spore
GII90_18700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII90_18710	COG4836	Membrane
GII90_18720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII90_18725	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII90_18730	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII90_18735	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII90_18740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII90_18745	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII90_18750	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII90_18755	COG0356	it plays a direct role in the translocation of protons across the membrane
GII90_18765	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII90_18770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII90_18775	COG4475	Protein of unknown function (DUF436)
GII90_18780	COG0698	ribose 5-phosphate isomerase
GII90_18785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII90_18790	COG1971	Probably functions as a manganese efflux pump
GII90_18795	COG0009	L-threonylcarbamoyladenylate synthase
GII90_18800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII90_18820	COG2890	protein-(glutamine-N5) methyltransferase activity
GII90_18825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII90_18830	COG0346	lactoylglutathione lyase activity
GII90_18835	COG0789	Transcriptional regulator
GII90_18840	COG0679	Auxin Efflux Carrier
GII90_18845	COG0281	malic enzyme
GII90_18850	COG1435	thymidine kinase activity
GII90_18855	COG0254	rRNA binding
GII90_18860	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII90_18870	COG1494	fructose-1,6-bisphosphatase
GII90_18875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII90_18880	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII90_18885	COG0191	fructose-bisphosphate aldolase activity
GII90_18890	COG2204	response regulator
GII90_18895	COG4821	SIS domain
GII90_18900	COG0504	CTP synthase activity
GII90_18905	COG3343	RNA polymerase activity
GII90_18910	COG1960	acyl-CoA dehydrogenase activity
GII90_18915	COG0247	lactate metabolic process
GII90_18915	COG2181	nitrate reductase activity
GII90_18920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII90_18925	COG4294	response to UV
GII90_18935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII90_18940	COG1132	(ABC) transporter
GII90_18945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII90_18955	COG2181	nitrate reductase activity
GII90_18960	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GII90_18965	COG1140	nitrate reductase beta subunit
GII90_18970	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII90_18975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII90_18985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII90_18990	COG2223	nitrite transmembrane transporter activity
GII90_18995	COG0018	arginyl-trna synthetase
GII90_19000	COG4506	Protein conserved in bacteria
GII90_19015	COG0535	radical SAM domain protein
GII90_19025	COG1131	(ABC) transporter
GII90_19030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII90_19035	COG0612	Peptidase, M16
GII90_19040	COG0612	Peptidase, M16
GII90_19050	COG3391	amine dehydrogenase activity
GII90_19055	COG3391	amine dehydrogenase activity
GII90_19065	COG0457	Tetratricopeptide repeat
GII90_19075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII90_19080	COG0010	Belongs to the arginase family
GII90_19085	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII90_19090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII90_19100	COG1994	Peptidase M50
GII90_19105	COG1942	4-Oxalocrotonate Tautomerase
GII90_19110	COG1846	Transcriptional regulator
GII90_19115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII90_19120	COG0477	Major facilitator Superfamily
GII90_19125	COG1959	2 iron, 2 sulfur cluster binding
GII90_19130	COG3465	dGTPase activity
GII90_19135	COG1078	dGTPase activity
GII90_19140	COG4844	belongs to the
GII90_19150	COG0697	spore germination
GII90_19155	COG0095	Lipoate-protein ligase
GII90_19160	COG0583	DNA-binding transcription factor activity
GII90_19165	COG0280	phosphate acetyltransferase
GII90_19175	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_19180	COG0436	Aminotransferase
GII90_19185	COG2814	Major facilitator Superfamily
GII90_19190	COG0151	Belongs to the GarS family
GII90_19195	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_19200	COG1917	Cupin 2, conserved barrel domain protein
GII90_19205	COG0077	Prephenate dehydratase
GII90_19210	COG2814	Major facilitator Superfamily
GII90_19215	COG0833	amino acid
GII90_19220	COG4187	Peptidase family M20/M25/M40
GII90_19225	COG1012	belongs to the aldehyde dehydrogenase family
GII90_19230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII90_19240	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII90_19245	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII90_19250	COG1088	dTDP-glucose 4,6-dehydratase activity
GII90_19255	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII90_19260	COG3980	spore coat polysaccharide biosynthesis protein
GII90_19265	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII90_19270	COG2089	acid synthase
GII90_19275	COG0456	acetyltransferase
GII90_19280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII90_19285	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII90_19290	COG0463	Glycosyl transferase, family 2
GII90_19300	COG2363	Small membrane protein
GII90_19305	COG2233	PERMEase
GII90_19315	COG1012	belongs to the aldehyde dehydrogenase family
GII90_19320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII90_19325	COG1216	Glycosyl transferase, family 2
GII90_19340	COG1695	Transcriptional regulator
GII90_19345	COG0351	phosphomethylpyrimidine kinase
GII90_19355	COG1621	beta-fructofuranosidase activity
GII90_19360	COG1263	PTS System
GII90_19360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_19365	COG2116	formate transmembrane transporter activity
GII90_19370	COG3711	transcriptional antiterminator
GII90_19380	COG1404	Belongs to the peptidase S8 family
GII90_19385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII90_19390	COG0778	Nitroreductase
GII90_19395	COG0772	Belongs to the SEDS family
GII90_19405	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII90_19410	COG1845	cytochrome c oxidase, subunit III
GII90_19415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII90_19420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII90_19425	COG2261	transglycosylase associated protein
GII90_19430	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII90_19435	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII90_19440	COG2246	polysaccharide biosynthetic process
GII90_19445	COG1309	transcriptional regulator
GII90_19455	COG3162	membrane
GII90_19460	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII90_19465	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII90_19470	COG2837	iron assimilation
GII90_19475	COG2822	iron ion transport
GII90_19480	COG0672	)-iron permease
GII90_19485	COG0352	thiamine-phosphate diphosphorylase activity
GII90_19490	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII90_19495	COG0583	DNA-binding transcription factor activity
GII90_19500	COG1380	Effector of murein hydrolase LrgA
GII90_19505	COG1346	cytolysis
GII90_19510	COG2814	Major facilitator Superfamily
GII90_19515	COG4895	conserved protein (DUF2196)
GII90_19520	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII90_19525	COG0346	lactoylglutathione lyase activity
GII90_19535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII90_19540	COG1404	Belongs to the peptidase S8 family
GII90_19545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_19545	COG1263	PTS System
GII90_19550	COG3711	transcriptional antiterminator
GII90_19555	COG1442	glycosyl transferase family 8
GII90_19560	COG5522	Integral membrane protein (intg_mem_TP0381)
GII90_19565	COG1846	Transcriptional regulator
GII90_19570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII90_19575	COG2234	aminopeptidase activity
GII90_19580	COG2357	RelA SpoT domain protein
GII90_19585	COG1575	Belongs to the MenA family. Type 1 subfamily
GII90_19600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII90_19605	COG1696	Membrane protein involved in D-alanine export
GII90_19610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII90_19615	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII90_19620	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII90_19625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII90_19630	COG1486	melibiose metabolic process
GII90_19635	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII90_19640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII90_19645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII90_19650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII90_19650	COG3711	transcriptional antiterminator
GII90_19660	COG2094	Belongs to the DNA glycosylase MPG family
GII90_19665	COG0753	catalase activity
GII90_19670	COG2814	Major facilitator Superfamily
GII90_19675	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII90_19680	COG1131	(ABC) transporter
GII90_19700	COG1595	DNA-templated transcription, initiation
GII90_19705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII90_19710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII90_19715	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII90_19720	COG4988	ABC transporter
GII90_19725	COG1294	oxidase, subunit
GII90_19730	COG1271	oxidase subunit
GII90_19735	COG3493	citrate carrier protein
GII90_19740	COG0501	Belongs to the peptidase M48B family
GII90_19750	COG0726	polysaccharide deacetylase
GII90_19755	COG3842	ATPase activity
GII90_19760	COG2508	Transcriptional regulator
GII90_19765	COG1012	belongs to the aldehyde dehydrogenase family
GII90_19770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII90_19780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII90_19785	COG1881	PFAM PEBP family protein
GII90_19790	COG0583	DNA-binding transcription factor activity
GII90_19800	COG4585	Histidine kinase
GII90_19805	COG2197	response regulator
GII90_19810	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII90_19820	COG4894	glucomannan catabolic process
GII90_19825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII90_19830	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII90_19835	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_19840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII90_19845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII90_19850	COG2610	gluconate transmembrane transporter activity
GII90_19855	COG0500	methyltransferase
GII90_19860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII90_19875	COG0693	protein deglycase activity
GII90_19875	COG0753	catalase activity
GII90_19880	COG2851	Citrate transporter
GII90_19885	COG2273	Hydrolase Family 16
GII90_19890	COG3711	transcriptional antiterminator
GII90_19900	COG2270	Major facilitator Superfamily
GII90_19905	COG0513	Belongs to the DEAD box helicase family
GII90_19910	COG2755	lipolytic protein G-D-S-L family
GII90_19910	COG3401	FG-GAP repeat protein
GII90_19970	COG3209	COG3209 Rhs family protein
GII90_19975	COG0697	spore germination
GII90_19980	COG0589	response to stress
GII90_19985	COG2723	6-phospho-beta-galactosidase activity
GII90_19990	COG1263	PTS System
GII90_19990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_19990	COG2190	(PTS) system
GII90_20005	COG5444	nuclease activity
GII90_20020	COG3507	Belongs to the glycosyl hydrolase 43 family
GII90_20035	COG2986	histidine ammonia-lyase
GII90_20040	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII90_20045	COG1228	amidohydrolase
GII90_20050	COG0010	Belongs to the arginase family
GII90_20055	COG0833	amino acid
GII90_20060	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII90_20065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII90_20070	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII90_20075	COG2390	Transcriptional regulator
GII90_20085	COG3192	ethanolamine utilization protein
GII90_20090	COG2079	MmgE PrpD family protein
GII90_20100	COG1126	abc transporter atp-binding protein
GII90_20105	COG0765	amino acid transport
GII90_20110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII90_20130	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII90_20135	COG0561	phosphatase activity
GII90_20165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII90_20170	COG5294	Protein conserved in bacteria
GII90_20175	COG0577	efflux transmembrane transporter activity
GII90_20180	COG1136	(ABC) transporter
GII90_20185	COG2205	protein histidine kinase activity
GII90_20190	COG0745	RESPONSE REGULATOR receiver
GII90_20195	COG0191	fructose-bisphosphate aldolase activity
GII90_20200	COG1082	Xylose isomerase domain protein TIM barrel
GII90_20205	COG1082	Xylose isomerase domain protein TIM barrel
GII90_20210	COG0673	inositol 2-dehydrogenase activity
GII90_20215	COG2814	Major facilitator Superfamily
GII90_20220	COG1082	Xylose isomerase domain protein TIM barrel
GII90_20225	COG3962	Belongs to the TPP enzyme family
GII90_20230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII90_20235	COG3718	enzyme involved in inositol metabolism
GII90_20240	COG1012	belongs to the aldehyde dehydrogenase family
GII90_20245	COG1349	DNA-binding transcription factor activity
GII90_20250	COG0667	Aldo Keto reductase
GII90_20265	COG2814	Major facilitator Superfamily
GII90_20270	COG0326	Molecular chaperone. Has ATPase activity
GII90_20280	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_20285	COG1309	transcriptional regulator
GII90_20290	COG1012	belongs to the aldehyde dehydrogenase family
GII90_20295	COG0456	acetyltransferase
GII90_20300	COG2850	peptidyl-arginine hydroxylation
GII90_20305	COG2226	methyltransferase
GII90_20320	COG0367	asparagine synthase
GII90_20325	COG2814	Major facilitator Superfamily
GII90_20330	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GII90_20340	COG1714	RDD family
GII90_20345	COG2311	Membrane
GII90_20350	COG1917	Cupin 2, conserved barrel domain protein
GII90_20355	COG1309	transcriptional regulator
GII90_20360	COG1028	Short-chain dehydrogenase reductase Sdr
GII90_20365	COG1846	Transcriptional regulator
GII90_20370	COG1380	Effector of murein hydrolase LrgA
GII90_20375	COG1346	cytolysis
GII90_20380	COG5039	Polysaccharide pyruvyl transferase
GII90_20385	COG1929	Belongs to the glycerate kinase type-1 family
GII90_20390	COG1802	Transcriptional regulator
GII90_20395	COG1070	Carbohydrate kinase
GII90_20400	COG2610	gluconate transmembrane transporter activity
GII90_20405	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII90_20410	COG0450	alkyl hydroperoxide reductase
GII90_20415	COG3634	alkyl hydroperoxide reductase activity
GII90_20420	COG2723	6-phospho-beta-galactosidase activity
GII90_20425	COG2190	(PTS) system
GII90_20430	COG2190	(PTS) system
GII90_20430	COG1263	PTS System
GII90_20430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII90_20435	COG2188	Transcriptional regulator
GII90_20450	COG1131	(ABC) transporter
GII90_20455	COG1994	Peptidase M50
GII90_20460	COG0535	radical SAM domain protein
GII90_20470	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII90_20475	COG5293	efflux transmembrane transporter activity
GII90_20485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII90_20490	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII90_20505	COG1063	alcohol dehydrogenase
GII90_20525	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII90_20530	COG0456	acetyltransferase
GII90_20535	COG0457	Tetratricopeptide repeat
GII90_20545	COG0010	Belongs to the arginase family
GII90_20550	COG0833	amino acid
GII90_20555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII90_20560	COG3829	transcription factor binding
GII90_20575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII90_20580	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII90_20585	COG4853	Protein conserved in bacteria
GII90_20590	COG4863	YycH protein
GII90_20595	COG5002	protein histidine kinase activity
GII90_20600	COG0745	RESPONSE REGULATOR receiver
GII90_20630	COG0346	lactoylglutathione lyase activity
GII90_20635	COG0305	Participates in initiation and elongation during chromosome replication
GII90_20650	COG3093	addiction module antidote protein HigA
GII90_20655	COG2807	transmembrane transport
GII90_20660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII90_20665	COG0359	binds to the 23S rRNA
GII90_20670	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII90_20675	COG4241	membrane
GII90_20685	COG5577	PFAM Coat F domain
GII90_20690	COG1733	regulation of RNA biosynthetic process
GII90_20695	COG1227	inorganic diphosphatase activity
GII90_20710	COG2271	Major facilitator Superfamily
GII90_20745	COG1131	(ABC) transporter
GII90_20760	COG4319	ketosteroid isomerase
GII90_20765	COG1357	PFAM Pentapeptide repeats (8 copies)
GII90_20770	COG2814	Major facilitator Superfamily
GII90_20775	COG0583	DNA-binding transcription factor activity
GII90_20780	COG2153	protein acetylation
GII90_20790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII90_20795	COG1846	Transcriptional regulator
GII90_20800	COG2153	protein acetylation
GII90_20805	COG2364	Membrane
GII90_20810	COG0456	acetyltransferase
GII90_20815	COG2315	Protein conserved in bacteria
GII90_20820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII90_20830	COG2814	Major facilitator Superfamily
GII90_20840	COG1331	Highly conserved protein containing a thioredoxin domain
GII90_20845	COG0789	Transcriptional regulator
GII90_20850	COG0697	spore germination
GII90_20855	COG1331	Highly conserved protein containing a thioredoxin domain
GII90_20860	COG1266	CAAX protease self-immunity
GII90_20865	COG2814	Major facilitator Superfamily
GII90_20865	COG0477	Major facilitator Superfamily
GII90_20870	COG0110	maltose O-acetyltransferase activity
GII90_20875	COG0346	lactoylglutathione lyase activity
GII90_20880	COG1609	Transcriptional regulator
GII90_20885	COG0708	Exodeoxyribonuclease III
GII90_20890	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII90_20895	COG0629	single-stranded DNA binding
GII90_20900	COG0360	Binds together with S18 to 16S ribosomal RNA
GII90_20905	COG0012	GTP binding
GII90_20910	COG0243	molybdopterin cofactor binding
GII90_20915	COG4481	Protein conserved in bacteria
GII90_20920	COG3949	Membrane
GII90_20930	COG1475	DNA binding
GII90_20935	COG1192	Involved in chromosome partitioning
GII90_20945	COG1475	DNA binding
GII90_20950	COG0357	Ribosomal RNA small subunit methyltransferase G
GII90_20955	COG0445	tRNA wobble uridine modification
GII90_20960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII90_20965	COG1847	R3H domain protein
GII90_20970	COG0706	membrane insertase activity
GII90_20975	COG0594	ribonuclease P activity
GII90_20980	COG0230	Belongs to the bacterial ribosomal protein bL34 family