locus-tag class description DJ572_00020 ENOG4108Z0C Uvrb UvrC protein DJ572_00025 ENOG41066A3 ATP guanido phosphotransferase DJ572_00035 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) DJ572_00040 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) DJ572_00045 ENOG4105CTP PilT protein domain protein DJ572_00050 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) DJ572_00055 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) DJ572_00060 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) DJ572_00070 ENOG4105D7W serine acetyltransferase DJ572_00075 ENOG4105C8N cysteinyl-tRNA synthetase DJ572_00080 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) DJ572_00085 ENOG4105C2N RNA methyltransferase TrmH family group 3 DJ572_00090 ENOG4105M0M Tetracycline resistance protein DJ572_00110 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) DJ572_00115 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) DJ572_00125 ENOG4108VZM 50s ribosomal protein L10 DJ572_00130 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) DJ572_00135 ENOG4107Y49 methyltransferase DJ572_00140 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DJ572_00145 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DJ572_00150 ENOG4105XPM ribosomal protein DJ572_00155 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) DJ572_00160 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) DJ572_00165 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) DJ572_00170 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) DJ572_00175 ENOG4107SKW Inherit from COG: Alpha beta hydrolase DJ572_00180 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) DJ572_00185 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) DJ572_00190 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) DJ572_00195 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) DJ572_00200 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity DJ572_00205 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) DJ572_00210 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) DJ572_00215 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) DJ572_00220 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) DJ572_00225 ENOG41082SA 50s ribosomal protein l29 DJ572_00230 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal DJ572_00235 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) DJ572_00245 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits DJ572_00255 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) DJ572_00260 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) DJ572_00265 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) DJ572_00270 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) DJ572_00275 ENOG4105VPB 50S ribosomal protein L30 DJ572_00280 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) DJ572_00285 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DJ572_00295 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DJ572_00305 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) DJ572_00315 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits DJ572_00320 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) DJ572_00325 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DJ572_00330 ENOG4108ZT0 50S ribosomal protein l17 DJ572_00335 ENOG4108JJB ABC transporter DJ572_00340 ENOG4108JJB ABC transporter DJ572_00345 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) DJ572_00350 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) DJ572_00355 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) DJ572_00360 ENOG4108UJD 30S ribosomal protein S9 DJ572_00365 ENOG4108I0C methyltransferase DJ572_00380 ENOG4105D1F ATP-binding protein DJ572_00395 ENOG4108NMV polysaccharide deacetylase DJ572_00560 ENOG4105CHH sulfate transporter DJ572_00570 ENOG4108SA1 esterase DJ572_00590 ENOG410874W AraC family transcriptional regulator DJ572_00595 ENOG4105EHZ conserved protein UCP016719 DJ572_00600 ENOG4105D17 glycoside hydrolase, family 3 domain protein DJ572_00620 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate DJ572_00630 ENOG4105EWC Purine nucleoside phosphorylase DJ572_00660 ENOG4105EMN RNA polymerase sigma factor DJ572_00670 ENOG4105C8B TIGR00159 family DJ572_00675 ENOG4107U5W ybbr family DJ572_00680 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) DJ572_00685 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) DJ572_00695 ENOG4105D03 DNA-3-methyladenine glycosylase II DJ572_00705 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DJ572_00710 ENOG4108TWJ NADH dehydrogenase subunit 5 DJ572_00730 ENOG4105GPN Uncharacterized conserved protein (DUF2294) DJ572_00735 ENOG4105WAB arsR family transcriptional regulator DJ572_00740 ENOG4108RWP Major Facilitator Superfamily protein DJ572_00755 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DJ572_00780 ENOG4105BZ1 (ABC) transporter DJ572_00805 ENOG4105G0J serine threonine protein kinase DJ572_00815 ENOG4106K80 DJ572_00825 ENOG4106DDH Sporulation-specific SASP protein DJ572_00835 ENOG4108HWY Beta-lactamase DJ572_00840 ENOG4107E6A Cytochrome p-450 DJ572_00850 ENOG4107QTZ amino acid DJ572_00855 ENOG4107VXM glycerophosphoryl diester phosphodiesterase DJ572_00860 ENOG4105CXY transporter DJ572_00875 ENOG410645S MarR family Transcriptional regulator DJ572_00880 ENOG4105DCM major facilitator superfamily DJ572_00895 ENOG410631K Membrane DJ572_00900 ENOG4106AXJ AraC family transcriptional regulator DJ572_00905 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR DJ572_00910 ENOG4108TCS Glutamyl endopeptidase DJ572_00920 ENOG4108WC5 Alpha Beta Hydrolase Fold protein DJ572_00925 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DJ572_00930 ENOG4107ZTW SNARE associated Golgi DJ572_00945 ENOG4105C72 UPF0176 protein DJ572_00955 ENOG4108IIZ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane DJ572_00960 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) DJ572_00965 ENOG4108X79 transcriptional regulator DJ572_00975 ENOG4105CM2 brancheD-chain amino acid aminotransferase DJ572_00980 ENOG4108IQI permease DJ572_00985 ENOG4108J5H Homocysteine s-methyltransferase DJ572_01000 ENOG4105CSV Glutaminase DJ572_01020 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase DJ572_01025 ENOG4105C26 Dehydrogenase DJ572_01030 ENOG4105DJB Major Facilitator Superfamily DJ572_01035 ENOG4105EQX glucarate dehydratase DJ572_01040 ENOG41073TP transcriptional regulator DJ572_01045 ENOG4105CTX dehydratase DJ572_01060 ENOG4106UX7 integral membrane protein DJ572_01065 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ572_01095 ENOG4105MUA Resistance protein DJ572_01105 ENOG4105DGI Alkaline phosphatase DJ572_01110 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) DJ572_01115 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) DJ572_01120 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) DJ572_01125 ENOG4107EPV Aminotransferase class V DJ572_01130 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ572_01135 ENOG4105J7D transcriptional regulator DJ572_01140 ENOG4107RB3 L-asparaginase DJ572_01145 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold DJ572_01155 ENOG41060AI SEC-C motif DJ572_01165 ENOG4107Y7X LytTR DJ572_01170 ENOG4108IUW ABC transporter DJ572_01175 ENOG4108SDH ABC, transporter DJ572_01180 ENOG4107SET aldo keto reductase DJ572_01210 ENOG4105H9W Short-chain dehydrogenase reductase Sdr DJ572_01220 ENOG4105DSE periplasmic solute binding protein DJ572_01225 ENOG4105DIK (ABC) transporter DJ572_01235 ENOG4105DEN Luciferase family DJ572_01240 ENOG4108N0M stress protein DJ572_01245 ENOG4106FN3 tellurium resistance protein DJ572_01250 ENOG4106FN3 tellurium resistance protein DJ572_01255 ENOG4107TS3 membrane protein, TerC DJ572_01260 ENOG4108TTB tellurium resistance protein DJ572_01270 ENOG41079KZ Major Facilitator Superfamily DJ572_01280 ENOG4107XZQ multidrug resistance protein DJ572_01285 ENOG4108A65 Transcriptional regulator DJ572_01290 ENOG4108IJ7 Glycine betaine DJ572_01295 ENOG4107SQ8 Glycine betaine DJ572_01325 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DJ572_01360 ENOG4105EIG urea carboxylase-associated protein 1 DJ572_01365 ENOG4107RA1 nh(3)-dependent nad( ) synthetase DJ572_01370 ENOG4105I1F Resistance protein DJ572_01375 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) DJ572_01380 ENOG41089UC methyltransferase, type 11 DJ572_01385 ENOG4105C5Q Transcriptional regulator DJ572_01390 ENOG4105I82 acetyl xylan esterase DJ572_01395 ENOG410756H nucleotidyltransferase DJ572_01405 ENOG4105C26 Dehydrogenase DJ572_01410 ENOG4105CK7 Sodium proline symporter DJ572_01415 ENOG4107YHD transcriptional regulator DJ572_01425 ENOG4108PJD permease DJ572_01430 ENOG4105U6C Alpha beta hydrolase fold protein DJ572_01440 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DJ572_01445 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit DJ572_01450 ENOG4108IFG nitrite reductase, (NAD(P)H) DJ572_01455 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) DJ572_01475 ENOG4105S7A ErfK ybiS ycfS ynhG family protein DJ572_01485 ENOG4105CKI cobalamin synthesis protein DJ572_01490 ENOG4105E5Q amino acid AbC transporter DJ572_01495 ENOG4107XKZ Amino acid ABC superfamily ATP binding cassette transporter binding protein DJ572_01500 ENOG4105HHM rdd domain containing protein DJ572_01510 ENOG4105CS2 ec 3.2.1.21 DJ572_01525 ENOG4105C8Q Methyl-accepting chemotaxis DJ572_01530 ENOG41080HJ 6-phospho 3-hexuloisomerase DJ572_01535 ENOG4108VA3 3-hexulose-6-phosphate synthase DJ572_01540 ENOG4105KVH Transcriptional regulator DJ572_01545 ENOG4105CEY Amp-dependent synthetase and ligase DJ572_01575 ENOG4105SX7 Transporter DJ572_01585 ENOG4105W8Z 4'-phosphopantetheinyl transferase DJ572_01595 ENOG4105CDA abc transporter atp-binding protein DJ572_01600 ENOG4105DRP amino acid AbC transporter DJ572_01610 ENOG4106P55 Transcriptional regulator DJ572_01615 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DJ572_01620 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) DJ572_01625 ENOG41069ZX DJ572_01630 ENOG41069ZX DJ572_01640 ENOG4105DUX Transporter DJ572_01655 ENOG4105E1K spore germination protein DJ572_01675 ENOG4107WD8 ABC transporter, permease DJ572_01680 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ572_01685 ENOG4105BZU Histidine kinase DJ572_01710 ENOG4105CFH Aspartokinase DJ572_01715 ENOG4105DHS permease protein DJ572_01720 ENOG4105CM4 permease protein DJ572_01725 ENOG4108IPW abc transporter atp-binding protein DJ572_01740 ENOG4105R8C Transcriptional regulator DJ572_01745 ENOG4108DBC nitroreductase DJ572_01750 ENOG41067V3 Antibiotic biosynthesis monooxygenase DJ572_01755 ENOG4105YVS arsR family transcriptional regulator DJ572_01765 ENOG4108JPW Aminotransferase DJ572_01770 ENOG4105C26 Dehydrogenase DJ572_01780 ENOG4105H9W Short-chain dehydrogenase reductase Sdr DJ572_01785 ENOG4105KTB nuclear export factor GLE1 DJ572_01790 ENOG4108T5E Copper resistance protein DJ572_01795 ENOG4108ZYE Transcriptional regulator DJ572_01820 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DJ572_01825 ENOG4108ZX0 Signal peptidase I DJ572_01850 ENOG4105E7W lamb ycsf family protein DJ572_01855 ENOG4105C5A transporter DJ572_01860 ENOG4105CFM UPF0317 protein DJ572_01865 ENOG4105P4J Allophanate hydrolase, subunit 1 DJ572_01875 ENOG4107258 Transcriptional regulator DJ572_01880 ENOG4105XJB lipolytic protein G-D-S-L family DJ572_01890 ENOG41061CK Antibiotic biosynthesis monooxygenase DJ572_01895 ENOG4107RVG penicillin-binding protein DJ572_01900 ENOG4107QM2 Aldo Keto reductase DJ572_01905 ENOG4105ETD TRANSCRIPTIONal DJ572_01915 ENOG4105HMZ Methyltransferase DJ572_01920 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DJ572_01935 ENOG410606W general stress protein DJ572_01945 ENOG4105VCH membrane DJ572_01955 ENOG4105C9U ATP-dependent DNA helicase RecQ DJ572_01970 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) DJ572_01975 ENOG4107R8N Glycosyl transferase, family 2 DJ572_01985 ENOG4105C0X amino acid DJ572_02010 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) DJ572_02020 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) DJ572_02025 ENOG4105EU9 DJ572_02030 ENOG4105QVS general stress protein DJ572_02035 ENOG41082W1 Cupin 2, conserved barrel domain protein DJ572_02050 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit DJ572_02055 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism DJ572_02060 ENOG4108MRH transcriptional regulatory protein DJ572_02065 ENOG4107QJT sodium dicarboxylate symporter DJ572_02070 ENOG4106F5Q Membrane DJ572_02075 ENOG4105CJ1 ABC, transporter DJ572_02090 ENOG4105FDT acyl-CoA dehydrogenase DJ572_02110 ENOG4105SZ6 Thioredoxin DJ572_02115 ENOG4105CPF Cell wall formation (By similarity) DJ572_02120 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) DJ572_02130 ENOG4105C1J atp-dependent rna helicase DJ572_02135 ENOG410905X membrane-flanked domain protein DJ572_02140 ENOG4105CKV Membrane DJ572_02150 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) DJ572_02155 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein DJ572_02160 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DJ572_02170 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) DJ572_02175 ENOG4107MMM Anti-sigma-factor antagonist DJ572_02180 ENOG4105FUA antagonist DJ572_02185 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase DJ572_02190 ENOG4107SGM protein serine threonine phosphatase DJ572_02195 ENOG4105WN5 stage II sporulation protein DJ572_02200 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) DJ572_02210 ENOG41064BQ Phosphatase DJ572_02315 ENOG4105VZ8 Transcriptional regulator DJ572_02340 ENOG4108V4B ThiJ pfpI DJ572_02345 ENOG4105VEQ Cold shock protein DJ572_02350 ENOG4108VJ1 Transcriptional regulator (CarD family DJ572_02365 ENOG4108MCI Transcriptional regulator, ARAC family DJ572_02370 ENOG4108UZ3 Transporter DJ572_02375 ENOG41086D8 Transcriptional regulator DJ572_02380 ENOG4107U9B transcriptional regulator DJ572_02385 ENOG4105DXI Major Facilitator superfamily DJ572_02395 ENOG4105CZ9 Domain of unknown function (DU1801) DJ572_02400 ENOG4105GIG DJ572_02425 ENOG4105KRI phosphocarrier protein (HPr DJ572_02430 ENOG4105ST3 Transcriptional regulator DJ572_02435 ENOG4105T38 integral membrane protein DJ572_02440 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DJ572_02445 ENOG4108ZMQ domain protein DJ572_02450 ENOG4105MJ9 esterase DJ572_02455 ENOG4107Z6X Transcriptional regulator DJ572_02465 ENOG4105EQ0 Major Facilitator superfamily DJ572_02470 ENOG4108JGH Tetr family transcriptional regulator DJ572_02480 ENOG41082YX Transcriptional regulator, arsr family DJ572_02485 ENOG4107R5R arsenical pump membrane protein DJ572_02495 ENOG4105Z7P Acetyltransferase (GNAT) family DJ572_02500 ENOG4107Y9U Membrane DJ572_02510 ENOG4108SQ9 flavin reductase domain protein, FMN-binding DJ572_02515 ENOG4108ZHR arsR family transcriptional regulator DJ572_02520 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) DJ572_02535 ENOG4105ENE Histidine kinase DJ572_02540 ENOG4108VB1 regulatoR DJ572_02545 ENOG4105EYF MMPL domain protein DJ572_02550 ENOG4108WC5 Alpha Beta Hydrolase Fold protein DJ572_02555 ENOG4108UQV Membrane DJ572_02560 ENOG4108Z5V transcriptional regulator, merr family DJ572_02565 ENOG41076HS cation diffusion facilitator family transporter DJ572_02570 ENOG4108TVJ Nitroreductase DJ572_02575 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase DJ572_02580 ENOG4108VGI doxx family DJ572_02585 ENOG4105XXY Thioredoxin DJ572_02600 ENOG410900G Protein of unknown function (DUF421) DJ572_02605 ENOG4108QY0 Membrane DJ572_02625 ENOG4105PF9 Transcriptional regulator DJ572_02635 ENOG4105WQG acetyltransferase DJ572_02645 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) DJ572_02650 ENOG4105ETE Transcriptional regulator (LacI family DJ572_02655 ENOG4105C54 Major Facilitator superfamily DJ572_02660 ENOG4107TRE AP endonuclease, family 2 DJ572_02670 ENOG4105C85 amino acid DJ572_02680 ENOG41062A4 Transcriptional regulator DJ572_02685 ENOG4105EYF MMPL domain protein DJ572_02690 ENOG4108TVJ Nitroreductase DJ572_02695 ENOG4105FS7 Transcriptional regulator DJ572_02700 ENOG4105C2C drug resistance transporter, Bcr CflA DJ572_02710 ENOG4105DRR Transcriptional regulator, GntR family DJ572_02715 ENOG4105VRS hydrolase family 18 DJ572_02730 ENOG4105G6Z alkaline phosphatase DJ572_02735 ENOG4108ZMX Domain of unknown function (DU1801) DJ572_02745 ENOG4108YM7 Gcn5-related n-acetyltransferase DJ572_02750 ENOG4107TVP HD domain protein DJ572_02755 ENOG41090UD (LipO)protein DJ572_02760 ENOG4105F27 Major Facilitator DJ572_02765 ENOG4105VZJ PTS System DJ572_02770 ENOG4105VCP PTS System DJ572_02775 ENOG4105CK1 PTS System DJ572_02780 ENOG4105CS2 ec 3.2.1.21 DJ572_02785 ENOG4108TZY GntR Family Transcriptional Regulator DJ572_02790 ENOG4105EVU fructokinase DJ572_02795 ENOG4105DG6 mannose-6-phosphate isomerase DJ572_02800 ENOG4105D3P Mannan endo-1,4-beta-mannosidase DJ572_02845 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) DJ572_02850 ENOG4105K8N protein family UPF0079, ATPase DJ572_02855 ENOG41072GX Peptidase M22 Glycoprotease DJ572_02860 ENOG410801F ribosomal-protein-alanine acetyltransferase DJ572_02865 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DJ572_02870 ENOG4105C5H ABC transporter DJ572_02875 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) DJ572_02880 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) DJ572_02885 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) DJ572_02890 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) DJ572_02905 ENOG4108TYN CAAX amino terminal protease family protein DJ572_02910 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) DJ572_02915 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) DJ572_02930 ENOG4105PGZ NB-ARC domain DJ572_02935 ENOG4105CPQ Dehydrogenase DJ572_02940 ENOG4105CT4 transporter DJ572_02950 ENOG41087YS Phage shock protein A DJ572_02955 ENOG4105DQX Zinc finger domain DJ572_02960 ENOG4108WV1 Pfam:DUF477 DJ572_02970 ENOG4108ZMR Ion transport 2 domain-containing protein DJ572_02975 ENOG4107QNK )-transporter DJ572_03005 ENOG4107YUH hydrolase DJ572_03015 ENOG4107STQ Multicopper oxidase DJ572_03020 ENOG4105C85 amino acid DJ572_03035 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DJ572_03055 ENOG4105C7N Xanthine uracil vitamin C permease DJ572_03080 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) DJ572_03085 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit DJ572_03090 ENOG4105C83 adenylosuccinate lyase DJ572_03095 ENOG4105C8V SAICAR synthetase DJ572_03100 ENOG4105VR9 phosphoribosylformylglycinamidine synthase DJ572_03105 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I DJ572_03110 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii DJ572_03120 ENOG4105CXB phosphoribosylaminoimidazole synthetase DJ572_03125 ENOG4108V3E phosphoribosylglycinamide formyltransferase DJ572_03130 ENOG4105DC1 bifunctional purine biosynthesis protein purh DJ572_03135 ENOG4105C12 Phosphoribosylglycinamide synthetase DJ572_03145 ENOG4105DVH amino acid DJ572_03160 ENOG4108R5T secreted protein DJ572_03165 ENOG4105KGF protein, YerC YecD DJ572_03170 ENOG4105CBC glutamate synthase DJ572_03175 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) DJ572_03180 ENOG4105C4R Atp-dependent dna helicase DJ572_03185 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) DJ572_03195 ENOG4105CRN Aminoglycoside phosphotransferase DJ572_03200 ENOG4105KT7 mgtC SapB transporter DJ572_03205 ENOG4105CK7 Sodium proline symporter DJ572_03210 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) DJ572_03215 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DJ572_03220 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) DJ572_03225 ENOG4108IG5 Transcriptional regulator DJ572_03235 ENOG4105CBD Diacylglycerol kinase DJ572_03240 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) DJ572_03315 ENOG4105CDY transcriptional regulatory protein DJ572_03325 ENOG4105M4P Tetr family transcriptional regulator DJ572_03330 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein DJ572_03335 ENOG4107S9F NmrA family DJ572_03350 ENOG4105WEF catalase DJ572_03355 ENOG4105M18 -acetyltransferase DJ572_03370 ENOG4105C2F Histidine kinase DJ572_03375 ENOG4105EQD regulatoR DJ572_03380 ENOG410769Z extracellular solute-binding protein family 1 DJ572_03385 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component DJ572_03390 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component DJ572_03395 ENOG4105F5H Glycosyl Hydrolase Family 88 DJ572_03400 ENOG41075H3 AraC family transcriptional regulator DJ572_03405 ENOG4107TDE lipolytic protein G-D-S-L family DJ572_03420 ENOG4105CX8 fg-gap repeat protein DJ572_03425 ENOG4105CX8 fg-gap repeat protein DJ572_03430 ENOG4107TDE lipolytic protein G-D-S-L family DJ572_03440 ENOG4105EKC DJ572_03445 ENOG4105E0S extracellular solute-binding protein family 1 DJ572_03455 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component DJ572_03460 ENOG4105F8D glycoside hydrolase family 4 DJ572_03465 ENOG4105H67 Protein of unknown function (DUF421) DJ572_03470 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) DJ572_03475 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DJ572_03495 ENOG4106I4J membrane DJ572_03500 ENOG4108PCN EamA-like transporter family DJ572_03505 ENOG41082F9 transcriptional regulator DJ572_03510 ENOG41061H0 Monooxygenase DJ572_03520 ENOG4108R1P DJ572_03525 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DJ572_03540 ENOG4105E0M Sulfatase DJ572_03545 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase DJ572_03555 ENOG41090R9 glycosyltransferase DJ572_03560 ENOG4107R51 Glycosyl transferase, family 2 DJ572_03565 ENOG41090R9 glycosyltransferase DJ572_03570 ENOG4105EU0 Major facilitator Superfamily DJ572_03580 ENOG4105CUB amino acid DJ572_03585 ENOG4105C26 Dehydrogenase DJ572_03590 ENOG4105FKZ Methyl-accepting chemotaxis DJ572_03595 ENOG4105C5H ABC transporter DJ572_03605 ENOG4107SWG transcriptional regulator MERR family DJ572_03610 ENOG4105DXB Major Facilitator superfamily DJ572_03625 ENOG4105C5H ABC transporter DJ572_03630 ENOG4105FDU atp-dependent rna helicase DJ572_03640 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein DJ572_03655 ENOG4105E6M Sulphatase-modifying factor protein DJ572_03660 ENOG4105E0A ABC, transporter DJ572_03665 ENOG4108U1V ABC transporter, permease DJ572_03670 ENOG4105DQ5 transport system permease protein DJ572_03675 ENOG4108HUF Transporter DJ572_03695 ENOG4108J20 pectate lyase DJ572_03700 ENOG4107QPK )-transporter DJ572_03710 ENOG4108MRH transcriptional regulatory protein DJ572_03735 ENOG410855V Acylphosphatase DJ572_03740 ENOG4108RPX mosc domain containing protein DJ572_03760 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) DJ572_03790 ENOG4105GEU Spore germination protein DJ572_03800 ENOG4108Q5U germination protein, ger(x)c family DJ572_03805 ENOG4105E1K spore germination protein DJ572_03810 ENOG4105C5Y PTS System DJ572_03815 ENOG4105CG3 alpha amylase, catalytic region DJ572_03820 ENOG4107414 GntR family transcriptional regulator DJ572_03825 ENOG4108RCM Nitroreductase DJ572_03830 ENOG4105CGH 5'-nucleotidase DJ572_03835 ENOG4107RKG DJ-1/PfpI family DJ572_03850 ENOG4105KJF protein tyrosine phosphatase DJ572_03860 ENOG4107U9T Pfam:Ribonuclease_BN DJ572_03865 ENOG4108ISG Major Facilitator DJ572_03870 ENOG4105UPD Calcium Proton DJ572_03880 ENOG4105D8X mechanosensitive ion channel DJ572_03900 ENOG4106KE4 Dehydrogenase DJ572_03905 ENOG4105D7N magnesium and cobalt transport protein CorA DJ572_03915 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) DJ572_03940 ENOG4107RUY (E1 component), alpha subunit DJ572_03950 ENOG4107QKR Dehydrogenase DJ572_03960 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family DJ572_03965 ENOG41069DP small acid-soluble spore protein DJ572_03970 ENOG4105KK4 UPF0060 membrane protein DJ572_03995 ENOG4105F8D glycoside hydrolase family 4 DJ572_04000 ENOG4108Q3X Transcriptional regulator DJ572_04005 ENOG4105CI1 PTS System DJ572_04015 ENOG4105BZ1 (ABC) transporter DJ572_04020 ENOG4105BZ1 (ABC) transporter DJ572_04030 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase DJ572_04035 ENOG4105BZU Histidine kinase DJ572_04040 ENOG4105WH1 Two component transcriptional regulator luxr family DJ572_04050 ENOG4105CJ1 ABC, transporter DJ572_04055 ENOG41090VJ ABC-2 type transporter DJ572_04060 ENOG4108KYE ABC-2 type transporter DJ572_04065 ENOG4105U3E Transcriptional regulator DJ572_04070 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold DJ572_04075 ENOG4105H93 Acyltransferase family DJ572_04080 ENOG4108YYS metal-dependent hydrolase (By similarity) DJ572_04085 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ572_04090 ENOG410834F Transcriptional regulator DJ572_04100 ENOG4108MES Periplasmic binding protein DJ572_04105 ENOG4105DQ5 transport system permease protein DJ572_04110 ENOG4108IHU transport system permease protein DJ572_04115 ENOG4105JAB phenazine biosynthesis protein, phzf family DJ572_04120 ENOG4107Y03 Nitroreductase DJ572_04135 ENOG4105ECP epimerase DJ572_04150 ENOG4105F27 Major Facilitator DJ572_04170 ENOG4106AKJ DJ572_04175 ENOG4105D74 hydrolase DJ572_04180 ENOG4105CKK Glycosyl transferase, family 2 DJ572_04185 ENOG4105EJV Membrane DJ572_04190 ENOG41067AE Membrane-bound metal-dependent hydrolase DJ572_04195 ENOG4105CEN a g-specific adenine glycosylase DJ572_04200 ENOG4106BXE DJ572_04205 ENOG4105CAN Short-chain dehydrogenase reductase Sdr DJ572_04220 ENOG4105EVI UPF0374 protein DJ572_04225 ENOG4105BZ1 (ABC) transporter DJ572_04230 ENOG4107NBY Membrane DJ572_04240 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DJ572_04245 ENOG4105G5W regulator Fur family DJ572_04355 ENOG4108N23 SpoOM-related protein DJ572_04370 ENOG4105EC3 peptidase S51, dipeptidase E DJ572_04375 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) DJ572_04380 ENOG4105DNP FAD linked oxidase domain protein DJ572_04395 ENOG4105E2Y ABC, transporter DJ572_04400 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein DJ572_04405 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DJ572_04410 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) DJ572_04420 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) DJ572_04425 ENOG4107D63 DJ572_04430 ENOG4105VZ8 Transcriptional regulator DJ572_04445 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) DJ572_04455 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) DJ572_04475 ENOG4105CYN Serine protein kinase DJ572_04480 ENOG4106AKX UPF0229 protein DJ572_04485 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes DJ572_04490 ENOG4105CW7 secretion protein, HlyD family DJ572_04495 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ572_04500 ENOG4105CS1 NAD(P)H quinone oxidoreductase DJ572_04520 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family DJ572_04525 ENOG4105CZV ABC transporter DJ572_04530 ENOG4105CJ1 ABC, transporter DJ572_04535 ENOG4108TU7 Inherit from COG: (ABC) transporter DJ572_04540 ENOG4105VEQ Cold shock protein DJ572_04555 ENOG4105BZU Histidine kinase DJ572_04595 ENOG4108YBP pseudouridine synthase DJ572_04605 ENOG41080XP Cbs domain DJ572_04610 ENOG4107YBY Hydrolase DJ572_04615 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase DJ572_04625 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DJ572_04630 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator DJ572_04640 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) DJ572_04645 ENOG4105C6V Glycerol-3-phosphate dehydrogenase DJ572_04655 ENOG4105BZU Histidine kinase DJ572_04660 ENOG4105WH1 Two component transcriptional regulator luxr family DJ572_04695 ENOG4105ED1 spovr family DJ572_04700 ENOG4105G6Z alkaline phosphatase DJ572_04715 ENOG4105BZN citrate synthase DJ572_04720 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DJ572_04725 ENOG4105CUB amino acid DJ572_04730 ENOG4105C8J )-transporter DJ572_04735 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DJ572_04750 ENOG4105J37 DJ572_04755 ENOG4108AEY RNA polymerase sigma factor DJ572_04760 ENOG4108FN7 Aldo keto reductase DJ572_04765 ENOG4105F6E Acyl-transferase DJ572_04770 ENOG4105C37 (CBS) domain DJ572_04780 ENOG4105CHM Aminotransferase DJ572_04785 ENOG4105C37 (CBS) domain DJ572_04795 ENOG4105WMR Protein CrcB homolog DJ572_04800 ENOG4108QXE glycerophosphoryl diester phosphodiesterase DJ572_04810 ENOG4105D64 Mechanosensitive ion channel DJ572_04815 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) DJ572_04820 ENOG4107VMI polysaccharide deacetylase DJ572_04825 ENOG4105F0I Aminotransferase DJ572_04845 ENOG4105BZ1 (ABC) transporter DJ572_04850 ENOG4105BZ1 (ABC) transporter DJ572_04875 ENOG410839P DJ572_04885 ENOG4106MP8 UPF0754 membrane protein DJ572_04890 ENOG4105WZB UPF0342 protein DJ572_04895 ENOG4105F1N DNA alkylation repair DJ572_04905 ENOG4105D4P Coproporphyrinogen iii oxidase DJ572_04910 ENOG4107S91 Sodium hydrogen exchanger DJ572_04915 ENOG4105NCW Trka-c domain protein DJ572_04925 ENOG4105CGU Enoyl-CoA hydratase DJ572_04935 ENOG4108IUX (ABC) transporter DJ572_04940 ENOG4105RHA ABC transporter, permease DJ572_04945 ENOG4107VRP DNA repair exonuclease DJ572_04950 ENOG4106D4I domain protein DJ572_04955 ENOG4105EQI Metal Dependent Phosphohydrolase DJ572_04965 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DJ572_05010 ENOG4105NBU tryptophan transport protein DJ572_05015 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) DJ572_05020 ENOG4105K59 histidine triad (HIT) protein DJ572_05055 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation DJ572_05060 ENOG4105BZ4 penicillin-binding protein DJ572_05065 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) DJ572_05070 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) DJ572_05075 ENOG4105C1Q protoporphyrinogen oxidase DJ572_05085 ENOG4105ECB domain protein DJ572_05095 ENOG41090T1 Membrane DJ572_05105 ENOG4105DER m42 family DJ572_05120 ENOG4106AXD DJ572_05125 ENOG4108RQ5 Beta-lactamase domain-containing protein DJ572_05130 ENOG4105DF9 Lipoate-protein, ligase DJ572_05140 ENOG4105CEY Amp-dependent synthetase and ligase DJ572_05150 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 DJ572_05155 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DJ572_05160 ENOG4105KD7 acetyltransferase DJ572_05170 ENOG4108HUF Transporter DJ572_05175 ENOG4107TB6 phosphoglycerate mutase DJ572_05185 ENOG4107F3J Amp-dependent synthetase and ligase DJ572_05190 ENOG4107ZYJ bioY protein DJ572_05195 ENOG4106YBV Methyl-accepting chemotaxis DJ572_05215 ENOG4105XVF Competence transcription factor DJ572_05220 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DJ572_05225 ENOG4105X3H Excalibur domain protein DJ572_05230 ENOG4105E1V na solute symporter DJ572_05235 ENOG4106CAD Protein of unknown function (DUF3311) DJ572_05240 ENOG41060YP DJ572_05255 ENOG4107SCK Monooxygenase DJ572_05260 ENOG4108INS Transcriptional regulator DJ572_05275 ENOG4105TRI Hydrolase DJ572_05290 ENOG4108KK1 membrane protein AbrB duplication DJ572_05300 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) DJ572_05305 ENOG4105VWP Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding DJ572_05320 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation DJ572_05330 ENOG4105EYH Exonuclease DJ572_05380 ENOG4105ERH Fumarylacetoacetate hydrolase DJ572_05390 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DJ572_05400 ENOG4105CAQ asparagine synthetase DJ572_05415 ENOG4105UQX Mate efflux family protein DJ572_05420 ENOG4106HBX Transcriptional Regulator AraC Family DJ572_05425 ENOG4105ETE Transcriptional regulator (LacI family DJ572_05430 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) DJ572_05435 ENOG4105SF0 DinB family DJ572_05440 ENOG4108ZUB Lysine exporter protein (Lyse ygga) DJ572_05445 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DJ572_05450 ENOG4105MYW Pentapeptide repeat protein DJ572_05455 ENOG4107S9D Alpha beta hydrolase DJ572_05460 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) DJ572_05465 ENOG4107RIQ Sulfate adenylate transferase DJ572_05470 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) DJ572_05475 ENOG4108N5B 2-phosphosulfolactate phosphatase DJ572_05480 ENOG41061P3 phosphosulfolactate synthase DJ572_05490 ENOG4105DIA mandelate racemase muconate lactonizing DJ572_05495 ENOG4107RCC Major Facilitator Superfamily DJ572_05500 ENOG4108SZE gCN5-related N-acetyltransferase DJ572_05505 ENOG4105MA6 gCN5-related N-acetyltransferase DJ572_05515 ENOG4108VPT UPF0234 protein DJ572_05520 ENOG4105QNR S1 RNA binding domain protein DJ572_05540 ENOG4105K7K Transcriptional regulator DJ572_05550 ENOG410751J DJ572_05555 ENOG4105D4Y metalloprotease DJ572_05560 ENOG4105EPR degv family DJ572_05565 ENOG4107AYK membrAne DJ572_05575 ENOG41073B9 DJ572_05580 ENOG4108KP7 hydrolase DJ572_05585 ENOG4108MXZ Esterase DJ572_05590 ENOG4105VG1 fes assembly suf system protein DJ572_05600 ENOG4105IQ5 FAD linked oxidase domain protein DJ572_05610 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase DJ572_05625 ENOG4105C8Y Acetylornithine aminotransferase DJ572_05630 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain DJ572_05640 ENOG4105DBV ornithine carbamoyltransferase DJ572_05665 ENOG4107RMD Basic membrane lipoprotein DJ572_05680 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DJ572_05685 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DJ572_05695 ENOG4105C3U ABC transporter DJ572_05700 ENOG4108JQ7 (ABC) transporter DJ572_05715 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DJ572_05725 ENOG4105C31 Tryptophanyl-tRNA synthetase DJ572_05730 ENOG4108J59 Extracellular solute-binding protein, family 5 DJ572_05735 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DJ572_05740 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DJ572_05750 ENOG4108JQ7 (ABC) transporter DJ572_05765 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) DJ572_05770 ENOG4108ZCF integral membrane protein DJ572_05775 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis DJ572_05785 ENOG4105DPN Oligoendopeptidase f DJ572_05800 ENOG4105T58 Dithiol-disulfide isomerase DJ572_05805 ENOG4108Z18 K06886 hemoglobin DJ572_05810 ENOG4105E4C Lytic transglycosylase catalytic DJ572_05815 ENOG4105MIX Adenylate cyclase DJ572_05830 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) DJ572_05835 ENOG4105EMS pseudouridine synthase DJ572_05850 ENOG4105ETU transcriptional activator (TenA DJ572_05855 ENOG4108VEU Thiamine monophosphate synthase DJ572_05870 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) DJ572_05875 ENOG4105D06 uba thif-type nad fad binding protein DJ572_05880 ENOG4105DWF phosphomethylpyrimidine kinase DJ572_05885 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH DJ572_05890 ENOG4107A88 DJ572_05940 ENOG4105ENA helicase DJ572_05955 ENOG4108ZMI UPF0477 protein DJ572_05965 ENOG4105C28 cystathionine DJ572_05970 ENOG4105C28 cystathionine DJ572_05975 ENOG4105D9U N-acetyltransferase DJ572_05980 ENOG4105JHY Membrane DJ572_06005 ENOG4106BHF DJ572_06055 ENOG4108PSK reductase DJ572_06070 ENOG4105DM4 PTS System DJ572_06075 ENOG4105DG6 mannose-6-phosphate isomerase DJ572_06080 ENOG4105G7B Protein of unknown function (DUF2992) DJ572_06085 ENOG4105VMI -acetyltransferase DJ572_06095 ENOG4108Z66 YbaK ebsC protein DJ572_06115 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) DJ572_06125 ENOG4108ZJ4 polysaccharide deacetylase DJ572_06130 ENOG4107CUJ Protein of unknown function (DUF2690) DJ572_06155 ENOG4108IEG Formate dehydrogenase Alpha subunit DJ572_06180 ENOG4106A3M Cytochrome p-450 DJ572_06185 ENOG41087PP glycosyltransferase MGT family DJ572_06195 ENOG4105EXQ uroporphyrinogen iii synthase hem4 DJ572_06200 ENOG4105C4B ABC transporter, permease DJ572_06205 ENOG4108IXI (ABC) transporter DJ572_06215 ENOG4105Q95 Cupin 2, conserved barrel domain protein DJ572_06230 ENOG4105D2H Uronic isomerase DJ572_06235 ENOG4105CT4 transporter DJ572_06240 ENOG4105DG4 malate L-lactate dehydrogenase DJ572_06245 ENOG4105CPQ Dehydrogenase DJ572_06250 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) DJ572_06255 ENOG4105DMW Dehydrogenase reductase DJ572_06260 ENOG4108I5G Major Facilitator superfamily DJ572_06265 ENOG4107KJX Transcriptional regulator DJ572_06270 ENOG4107QZW Altronate oxidoreductase DJ572_06275 ENOG4105CTX dehydratase DJ572_06280 ENOG4107TSN permease DJ572_06290 ENOG4105JD4 ATPase yjob DJ572_06305 ENOG41068K0 YCII-related domain DJ572_06310 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase DJ572_06315 ENOG4105KWG Pfam:DUF1696 DJ572_06320 ENOG4105K7W phage-related replication protein DJ572_06325 ENOG4105WEF catalase DJ572_06330 ENOG410635T phage-like element pbsx protein DJ572_06375 ENOG4108TFU terminase (Small subunit) DJ572_06380 ENOG4105IG6 Phage terminase, large subunit DJ572_06385 ENOG4108MDF Phage Portal Protein DJ572_06410 ENOG41060SN DJ572_06425 ENOG4105PQS phage protein DJ572_06430 ENOG4105FR7 XkdM protein, phage-like element PBSX DJ572_06435 ENOG4105MTC XkdN-like protein DJ572_06445 ENOG4108FKH Transglycosylase SLT domain DJ572_06445 ENOG4108FKH Transglycosylase SLT domain DJ572_06450 ENOG4108WZM domain protein DJ572_06455 ENOG4105X7F DJ572_06465 ENOG4105MFU Protein of unknown function (DUF2634) DJ572_06470 ENOG41066EA baseplate J family protein DJ572_06475 ENOG410906S phage-like element pbsx protein xkdt DJ572_06485 ENOG41068G1 DJ572_06515 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ572_06530 ENOG4105CJ3 phosphate transporter DJ572_06535 ENOG4107GRR phosphate transport regulator DJ572_06540 ENOG4107R7I amino acid DJ572_06550 ENOG4105EDW glycosyl transferase, family 39 DJ572_06555 ENOG4105CKK Glycosyl transferase, family 2 DJ572_06560 ENOG4105C0H protease DJ572_06570 ENOG4108ME1 Peptidase M55 D-aminopeptidase DJ572_06575 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DJ572_06580 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DJ572_06585 ENOG4105C3U ABC transporter DJ572_06595 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A DJ572_06600 ENOG4105DTQ mandelate racemase muconate lactonizing DJ572_06605 ENOG4107SN7 NLP P60 protein DJ572_06610 ENOG4108JQ7 (ABC) transporter DJ572_06615 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) DJ572_06620 ENOG4107TUM Amidinotransferase DJ572_06625 ENOG4108S4H thioesterase Superfamily protein DJ572_06630 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) DJ572_06650 ENOG4108428 Inherit from COG: -acetyltransferase DJ572_06660 ENOG41080TC multidrug resistance protein DJ572_06665 ENOG4105CIY formyltetrahydrofolate deformylase DJ572_06670 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) DJ572_06685 ENOG4105K56 Transcriptional regulator DJ572_06690 ENOG4108ZHJ Organic hydroperoxide resistance protein DJ572_06700 ENOG4107Y2X deaminase DJ572_06705 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) DJ572_06710 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DJ572_06720 ENOG4108W7F transporter, permease DJ572_06725 ENOG4108JJB ABC transporter DJ572_06730 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein DJ572_06735 ENOG4108X43 YKOF domain protein DJ572_06740 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ572_06745 ENOG41062D9 Histidine kinase DJ572_06755 ENOG4106849 propeptide, pepSY amd peptidase M4 DJ572_06770 ENOG4105CJW magnesium transporter DJ572_06775 ENOG4105V75 Transcriptional regulator DJ572_06820 ENOG4105DQE DNA ligase DJ572_06825 ENOG4105FDF Could be involved in DNA repair (By similarity) DJ572_06830 ENOG4105BZU Histidine kinase DJ572_06835 ENOG4107T5V SNARE associated Golgi DJ572_06840 ENOG4107TS3 membrane protein, TerC DJ572_06845 ENOG4108WZW RNA polymerase sigma DJ572_06855 ENOG410681C small acid-soluble spore protein DJ572_06865 ENOG4105D0M Protease HtpX homolog DJ572_06885 ENOG4108TGC Acyltransferase DJ572_06890 ENOG4105BZU Histidine kinase DJ572_06895 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DJ572_06900 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) DJ572_06905 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) DJ572_06910 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase DJ572_06920 ENOG4107T6J Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit DJ572_06925 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) DJ572_06930 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) DJ572_06935 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) DJ572_06955 ENOG4105BZU Histidine kinase DJ572_06960 ENOG41090MY MarR family Transcriptional regulator DJ572_06965 ENOG4105ER2 Ompa motb domain protein DJ572_06970 ENOG4105E14 MotA TolQ exbB proton channel DJ572_06985 ENOG4108K88 Membrane DJ572_06990 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) DJ572_06995 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase DJ572_07000 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DJ572_07005 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) DJ572_07015 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr DJ572_07020 ENOG4105FEA Spore maturation protein DJ572_07050 ENOG4105F0V Cell wall hydrolase DJ572_07065 ENOG4105C59 p-type ATPase DJ572_07075 ENOG4105DC7 peptidase M24 DJ572_07085 ENOG4105CID antiterminator DJ572_07095 ENOG4105KRI phosphocarrier protein (HPr DJ572_07100 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) DJ572_07110 ENOG4105F6S Spore photoproduct lyase DJ572_07120 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer DJ572_07125 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DJ572_07130 ENOG4105K4I Scp-like extracellular DJ572_07140 ENOG4105BZU Histidine kinase DJ572_07145 ENOG4105CHM Aminotransferase DJ572_07155 ENOG4107R88 Chemotaxis protein (CheV) DJ572_07160 ENOG4105UIN DJ572_07170 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein DJ572_07180 ENOG4105K6S Short-chain dehydrogenase reductase Sdr DJ572_07185 ENOG4105EPM Diguanylate phosphodiesterase DJ572_07190 ENOG4107IN1 Protein of unknown function (DUF1797) DJ572_07195 ENOG4108XRC Protein of unknown function (DUF458) DJ572_07225 ENOG4105NQC Flavodoxin DJ572_07235 ENOG4105CH2 amidohydrolase DJ572_07245 ENOG4105D8X mechanosensitive ion channel DJ572_07250 ENOG4105D3R alkyl hydroperoxide reductase DJ572_07255 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DJ572_07270 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) DJ572_07275 ENOG4105D06 uba thif-type nad fad binding protein DJ572_07280 ENOG4105CVM Molybdenum cofactor synthesis domain protein DJ572_07285 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein DJ572_07290 ENOG4108ZAF Molybdopterin DJ572_07295 ENOG41067WU Molybdopterin converting factor (Subunit 1) DJ572_07300 ENOG4105BZ1 (ABC) transporter DJ572_07305 ENOG4105BZ1 (ABC) transporter DJ572_07315 ENOG4107X8C Efflux transporter RND family MFP subunit DJ572_07320 ENOG4105C19 ABC transporter DJ572_07325 ENOG4107RBB ABC transporter, permease DJ572_07330 ENOG4105E98 transcriptional regulator DeoR family DJ572_07335 ENOG4105DE4 1-phosphofructokinase DJ572_07340 ENOG4105DM4 PTS System DJ572_07345 ENOG4105C3F Signal peptidase i DJ572_07355 ENOG4105C5H ABC transporter DJ572_07360 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) DJ572_07385 ENOG4105BZU Histidine kinase DJ572_07395 ENOG4107ZYR domain protein DJ572_07405 ENOG4105CN5 Metallo-Beta-Lactamase DJ572_07415 ENOG4108X4Q Hydrolase DJ572_07420 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DJ572_07440 ENOG4105CPP Dehydrogenase, E1 component DJ572_07445 ENOG4105C7S Dehydrogenase DJ572_07450 ENOG4107QN2 dihydrolipoyl dehydrogenase DJ572_07465 ENOG4105CXN decarboxylase DJ572_07470 ENOG4105WBI UPF0223 protein DJ572_07485 ENOG4105ECY inositol monophosphatase DJ572_07495 ENOG4105JQZ Methyltransferase DJ572_07535 ENOG4105CI3 gtp-binding protein typa DJ572_07540 ENOG4105QA2 DJ572_07555 ENOG4108IAB Phoh family DJ572_07565 ENOG4105CSV Glutaminase DJ572_07570 ENOG4105ZPI UPF0358 protein DJ572_07575 ENOG4105CNI cell division protein FtsW DJ572_07580 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) DJ572_07590 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) DJ572_07600 ENOG4105BZ9 Cytochrome C oxidase, subunit I DJ572_07605 ENOG4105CCU oxidase (Subunit III) DJ572_07610 ENOG41064X9 cytochrome C oxidase subunit IV DJ572_07625 ENOG41080XQ Signal transduction protein with cbs domains DJ572_07630 ENOG4106UY4 Inherit from COG: Scp-like extracellular DJ572_07650 ENOG4105WUC UPF0298 protein DJ572_07655 ENOG4106H78 methyltransferase DJ572_07660 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) DJ572_07665 ENOG4105H20 Sporulation integral membrane protein YlbJ DJ572_07670 ENOG4105D78 K07001 NTE family protein DJ572_07675 ENOG41063PX domain protein DJ572_07680 ENOG4105CDE UPF0348 protein DJ572_07690 ENOG4105KNH Nucleic acid-binding protein DJ572_07695 ENOG41067VY 50S ribosomal protein L32 DJ572_07720 ENOG4108V6E Cell division protein mraZ DJ572_07725 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) DJ572_07735 ENOG4105CJN penicillin-binding protein DJ572_07740 ENOG4105CJN penicillin-binding protein DJ572_07745 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) DJ572_07750 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) DJ572_07755 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) DJ572_07760 ENOG4105CNI cell division protein FtsW DJ572_07765 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) DJ572_07770 ENOG4105D4A Cell wall formation (By similarity) DJ572_07775 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) DJ572_07780 ENOG4108R2U division initiation protein DJ572_07790 ENOG4105K67 small basic protein DJ572_07795 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) DJ572_07800 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) DJ572_07810 ENOG4105FFI sigma-e processing peptidase spoiiga DJ572_07815 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ572_07825 ENOG4105DKW ABC transporter DJ572_07835 ENOG4105WR5 sporulation protein, YlmC YmxH family DJ572_07840 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase DJ572_07845 ENOG4105DFA alanine racemase domain protein DJ572_07850 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) DJ572_07855 ENOG41067XK integral membrane protein DJ572_07860 ENOG4105DBK s4 domain protein DJ572_07870 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) DJ572_07880 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) DJ572_07885 ENOG4105C34 Pseudouridine synthase DJ572_07890 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) DJ572_07900 ENOG4105CXT aspartate transcarbamylase DJ572_07910 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain DJ572_07915 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain DJ572_07920 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) DJ572_07925 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) DJ572_07930 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) DJ572_07935 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) DJ572_07940 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) DJ572_07950 ENOG4107S4M Sulfate adenylate transferase DJ572_07955 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) DJ572_07960 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DJ572_07965 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein DJ572_07970 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein DJ572_07975 ENOG4105F23 Fibronectin-binding protein DJ572_07985 ENOG4105DSJ YicC domain protein DJ572_07990 ENOG4105KC4 UPF0296 protein DJ572_07995 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) DJ572_08005 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase DJ572_08010 ENOG4105C25 Primosomal protein n' DJ572_08015 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DJ572_08020 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) DJ572_08025 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B DJ572_08030 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs DJ572_08035 ENOG4108ZF3 Phosphatase DJ572_08040 ENOG4105D9P serine threonine protein kinase DJ572_08045 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) DJ572_08050 ENOG4105DJV ribulose-phosphate 3-epimerase DJ572_08055 ENOG4105FJ0 thiamine DJ572_08065 ENOG4105VB9 50S ribosomal protein l28 DJ572_08070 ENOG4108ZAA Alkaline-shock protein DJ572_08075 ENOG4105DP4 dak2 domain fusion protein ylov DJ572_08085 ENOG4105EJQ L-serine dehydratase DJ572_08090 ENOG4105CB5 ATP-dependent DNA helicase recG DJ572_08095 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) DJ572_08110 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DJ572_08115 ENOG4105CHR reductase DJ572_08120 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) DJ572_08125 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) DJ572_08130 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) DJ572_08135 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) DJ572_08145 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) DJ572_08155 ENOG4105K5M 30s ribosomal protein S16 DJ572_08160 ENOG4108BW8 UPF0109 protein DJ572_08170 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) DJ572_08175 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) DJ572_08180 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) DJ572_08185 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) DJ572_08190 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) DJ572_08200 ENOG4105VM1 flagellar DJ572_08205 ENOG4105CMV Succinyl-CoA synthetase subunit beta DJ572_08210 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha DJ572_08215 ENOG4105C79 DNA protecting protein DprA DJ572_08220 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DJ572_08225 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) DJ572_08230 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DJ572_08235 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) DJ572_08240 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) DJ572_08250 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) DJ572_08255 ENOG4108ZC9 flagellar basal-body rod protein flgc DJ572_08260 ENOG4105VQ0 flagellar hook-basal body complex protein fliE DJ572_08265 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) DJ572_08270 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) DJ572_08285 ENOG4106YF4 Flagellar biosynthesis chaperone DJ572_08295 ENOG410696Y Flagellar hook-length control protein DJ572_08300 ENOG410822I Flagellar hook capping protein DJ572_08305 ENOG4108JQA flagellar DJ572_08310 ENOG41068WV flagellar FlbD family protein DJ572_08320 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) DJ572_08325 ENOG4105DD5 Flagellar motor switch protein DJ572_08330 ENOG4107YTP response regulator receiver protein DJ572_08340 ENOG4105CN7 Flagellar biosynthetic protein FliP DJ572_08345 ENOG4105VS8 Flagellar biosynthetic protein fliq DJ572_08350 ENOG4105D19 Role in flagellar biosynthesis (By similarity) DJ572_08355 ENOG4105D00 flagellar biosynthetic protein flhB DJ572_08360 ENOG4105D7B Flagellar biosynthesis protein flha DJ572_08365 ENOG4105FZW flagellar biosynthesis regulator FlhF DJ572_08375 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) DJ572_08380 ENOG4105CBS Chea signal transduction histidine kinase DJ572_08385 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis DJ572_08400 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ572_08410 ENOG4105CE9 30S ribosomal protein S2 DJ572_08415 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) DJ572_08425 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) DJ572_08430 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) DJ572_08435 ENOG4105KNE Phosphatidate cytidylyltransferase DJ572_08445 ENOG4105DZP Membrane-associated zinc metalloprotease DJ572_08450 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) DJ572_08455 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) DJ572_08460 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) DJ572_08465 ENOG4105CHV Transcription elongation factor NusA DJ572_08470 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination DJ572_08475 ENOG4105VHM ribosomal protein DJ572_08480 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) DJ572_08485 ENOG4105W7A Protein of unknown function (DUF503) DJ572_08490 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) DJ572_08495 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) DJ572_08500 ENOG4105DTN riboflavin biosynthesis protein ribF DJ572_08505 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) DJ572_08510 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) DJ572_08520 ENOG4105C1V Peptidase, M16 DJ572_08530 ENOG4105E35 Dipicolinate synthase subunit A DJ572_08535 ENOG4108S0H Dipicolinic acid synthetase, b subunit DJ572_08540 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) DJ572_08550 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DJ572_08560 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit DJ572_08570 ENOG4105CNU cell division protein FtsK DJ572_08575 ENOG4105FDP GntR family transcriptional regulator DJ572_08595 ENOG4108RKS Short-chain dehydrogenase reductase Sdr DJ572_08600 ENOG4105XZV Protein of unknown function (DUF3243) DJ572_08615 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase DJ572_08620 ENOG4105CEV competence damage-inducible protein DJ572_08630 ENOG4108A04 Beta-lactamase DJ572_08635 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) DJ572_08640 ENOG4105D48 metallophosphoesterase DJ572_08645 ENOG4105MCT stage V sporulation protein S DJ572_08655 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DJ572_08660 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DJ572_08675 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) DJ572_08680 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) DJ572_08690 ENOG4105IIP Membrane DJ572_08695 ENOG4105W1N transcriptional regulator DJ572_08700 ENOG4108151 Beta-lactamase domain protein DJ572_08710 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DJ572_08720 ENOG4107QKG PfaD family DJ572_08725 ENOG41062T2 Acyl carrier protein DJ572_08730 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase DJ572_08735 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase DJ572_08740 ENOG4108MGH Enoyl-CoA hydratase DJ572_08745 ENOG4108KQ6 Enoyl-CoA hydratase DJ572_08750 ENOG4105C0W non-ribosomal peptide synthetase DJ572_08755 ENOG4107SQU synthase DJ572_08765 ENOG4105C0W non-ribosomal peptide synthetase DJ572_08775 ENOG4106A3M Cytochrome p-450 DJ572_08790 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DJ572_08800 ENOG4105K7W phage-related replication protein DJ572_08805 ENOG4108X3M OsmC Ohr family protein DJ572_08810 ENOG410814C multidrug resistance protein DJ572_08830 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) DJ572_08835 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DJ572_08850 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) DJ572_08855 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DJ572_08860 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DJ572_08865 ENOG4105U6W MutT NUDIX family protein DJ572_08870 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DJ572_08875 ENOG4106F1P AAA ATPase, central domain protein DJ572_08880 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DJ572_08885 ENOG4105CXI aluminum resistance protein DJ572_08890 ENOG4105KV4 Transcriptional regulator DJ572_08895 ENOG4105C5F glutamine synthetase DJ572_08900 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DJ572_08910 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase DJ572_09090 ENOG4108FKH Transglycosylase SLT domain DJ572_09100 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj DJ572_09105 ENOG410651K Teichoic acid biosynthesis protein C DJ572_09115 ENOG41068G1 DJ572_09140 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase DJ572_09150 ENOG4106BHF DJ572_09160 ENOG41079P0 DJ572_09190 ENOG4106WTF Glycosyl transferase, family 2 DJ572_09195 ENOG4107RGC Glycosyl transferase, family 2 DJ572_09225 ENOG4107NTZ DJ572_09240 ENOG410907G DJ572_09260 ENOG4105CT4 transporter DJ572_09265 ENOG4105DSG hydrolase family 43 DJ572_09270 ENOG4105E2R ROK family DJ572_09275 ENOG4105C93 Xylose Isomerase DJ572_09280 ENOG4105CMG Carbohydrate kinase DJ572_09290 ENOG4107Y9E nuclease DJ572_09295 ENOG4105C54 Major Facilitator superfamily DJ572_09300 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DJ572_09310 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) DJ572_09375 ENOG4108Q8B Spore germination protein DJ572_09395 ENOG4105FVX DJ572_09405 ENOG4105K7W phage-related replication protein DJ572_09415 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) DJ572_09425 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) DJ572_09435 ENOG4108SVB resolvase DJ572_09440 ENOG4105VPS UPF0291 protein DJ572_09445 ENOG4105CV1 Transketolase (EC 2.2.1.1) DJ572_09465 ENOG4107QIV Cytochrome c biogenesis protein DJ572_09490 ENOG4107DZX Small, acid-soluble spore protein P DJ572_09500 ENOG4108I0Z Aconitate hydratase DJ572_09505 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DJ572_09520 ENOG41067CD Small, acid-soluble spore protein Tlp DJ572_09530 ENOG4105MI2 DJ572_09535 ENOG4105W8X HesB YadR YfhF-family protein DJ572_09540 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) DJ572_09545 ENOG4105K4P CoA-binding domain protein DJ572_09550 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DJ572_09570 ENOG4107QWR cellulase (EC 3.2.1.4) DJ572_09580 ENOG4108MYR Secreted protein DJ572_09585 ENOG4107SYN Glycosyl hydrolases family 43 DJ572_09595 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DJ572_09600 ENOG4107T5V SNARE associated Golgi DJ572_09610 ENOG4107QX3 carboxylase DJ572_09615 ENOG4105E39 Enoyl-CoA hydratase DJ572_09620 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase DJ572_09625 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit DJ572_09630 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DJ572_09635 ENOG4105CEY Amp-dependent synthetase and ligase DJ572_09640 ENOG4105C1G acyl-Coa dehydrogenase DJ572_09650 ENOG4105F32 YngK protein DJ572_09655 ENOG4106U2H Protein of unknown function (DUF1360) DJ572_09665 ENOG4105CEY Amp-dependent synthetase and ligase DJ572_09670 ENOG4105C0W non-ribosomal peptide synthetase DJ572_09680 ENOG4105C0W non-ribosomal peptide synthetase DJ572_09685 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family DJ572_09690 ENOG4108N2V aldose 1-epimerase DJ572_09695 ENOG4107QJQ Mate efflux family protein DJ572_09720 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DJ572_09725 ENOG4105SKE transcriptional Regulator LysR family DJ572_09730 ENOG4105CB2 alcohol dehydrogenase DJ572_09735 ENOG4105BZ8 glutamate synthase DJ572_09740 ENOG4105CBC glutamate synthase DJ572_09745 ENOG4105C5Q Transcriptional regulator DJ572_09750 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) DJ572_09755 ENOG4105II7 pyrroline-5-carboxylate reductase DJ572_09780 ENOG41068WN DJ572_09795 ENOG4105IE8 Alpha-ketoglutarate permease DJ572_09800 ENOG4107U6E carbohydrate kinase FGGY DJ572_09805 ENOG4108M3J Dehydrogenase DJ572_09810 ENOG4108J2R molybdopterin oxidoreductase DJ572_09835 ENOG4105EC8 Methyl-accepting chemotaxis DJ572_09845 ENOG4108YQE rare lipoprotein a DJ572_09850 ENOG4105XPP Protein of unknown function (DUF1275) DJ572_09855 ENOG4108NR7 pectate lyase DJ572_09860 ENOG4108RAV Conserved protein DJ572_09870 ENOG4105F0F Oxalate decarboxylase DJ572_09880 ENOG4105EPI acetyltransferase, (GNAT) family DJ572_09900 ENOG41073R8 VanW family DJ572_09915 ENOG4105NX3 Membrane DJ572_09925 ENOG4108Q5Y Membrane DJ572_09935 ENOG4108V4B ThiJ pfpI DJ572_09940 ENOG4108J4B Beta-lactamase DJ572_09960 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) DJ572_09965 ENOG4107T94 Endo-14-beta-xylanase DJ572_09975 ENOG4105YB8 TM2 domain containing protein DJ572_09980 ENOG4108IMY Transcriptional regulator DJ572_10100 ENOG410780I phosphoprotein phosphatase activity DJ572_10160 ENOG4108Z7R Chaperone CsaA DJ572_10165 ENOG4105FTV AraC Family Transcriptional Regulator DJ572_10170 ENOG4108HJF gCN5-related N-acetyltransferase DJ572_10180 ENOG4108W8B Beta-lactamase domain protein DJ572_10190 ENOG4105D29 Helix-turn-helix type 11 domain protein DJ572_10200 ENOG4105KTU Transcriptional regulator, arsr family DJ572_10210 ENOG4108SJC Membrane DJ572_10230 ENOG4105ECK Fatty Acid Desaturase DJ572_10235 ENOG4108ZGX Histidine kinase DJ572_10240 ENOG4108S01 response regulator DJ572_10250 ENOG41069ER domain protein DJ572_10255 ENOG4105C9U ATP-dependent DNA helicase RecQ DJ572_10270 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DJ572_10275 ENOG4105SCY DNAK suppressor DJ572_10315 ENOG4105C26 Dehydrogenase DJ572_10320 ENOG4105EWU Squalene--hopene cyclase DJ572_10325 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DJ572_10330 ENOG4105C8J )-transporter DJ572_10335 ENOG4105C09 Bile acid DJ572_10340 ENOG4105C7S Dehydrogenase DJ572_10350 ENOG4107T89 von Willebrand factor, type A DJ572_10355 ENOG4105GMT ATPase associated with various cellular activities aaa_5 DJ572_10365 ENOG4105K4H Nlp p60 protein DJ572_10370 ENOG41087PP glycosyltransferase MGT family DJ572_10380 ENOG4107QMU Mate efflux family protein DJ572_10385 ENOG4106SCS STAS domain DJ572_10405 ENOG4105FR1 rard protein DJ572_10420 ENOG4105C6Z Gluconate DJ572_10425 ENOG41090U3 tautomerase DJ572_10440 ENOG4105FBA Phospholipase Carboxylesterase DJ572_10455 ENOG4105E1V na solute symporter DJ572_10475 ENOG4108VXD carboxy-peptidase DJ572_10480 ENOG4105D3A purine nucleoside phosphorylase DeoD-type DJ572_10490 ENOG4106Z5R DJ572_10495 ENOG410841Q phosphoesterase PA-phosphatase related protein DJ572_10530 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein DJ572_10535 ENOG4108TSC N-acetyltransferase DJ572_10540 ENOG4107S4Y M20 DapE family protein YgeY DJ572_10555 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DJ572_10590 ENOG4107T32 3-phytase (EC 3.1.3.8) DJ572_10595 ENOG4105C5E polysaccharide biosynthesis protein DJ572_10600 ENOG4105E0X reductase DJ572_10605 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) DJ572_10625 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) DJ572_10630 ENOG41090WU lipolytic protein G-D-S-L family DJ572_10635 ENOG4108KF3 Electron transport protein SCO1 SenC DJ572_10645 ENOG4105C7B Threonine dehydratase DJ572_10655 ENOG4108UT2 hemolysin iii DJ572_10665 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) DJ572_10670 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) DJ572_10685 ENOG4107YX5 Pfam:DUF548 DJ572_10690 ENOG4108Y6J UPF0403 protein DJ572_10695 ENOG4105C01 Dihydroxy-acid dehydratase DJ572_10710 ENOG4108V06 Glutathione peroxidase DJ572_10715 ENOG4105CVG Homoserine O-transsuccinylase DJ572_10755 ENOG41081VK Ribonuclease DJ572_10780 ENOG410890F Dynamin family DJ572_10795 ENOG41065KQ synthase DJ572_10800 ENOG4105C2W permease DJ572_10805 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) DJ572_10810 ENOG4105CTD carboxy-peptidase DJ572_10815 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) DJ572_10820 ENOG4108UHU Aldolase DJ572_10825 ENOG4105D7K pfkb domain protein DJ572_10830 ENOG4108M60 Transcriptional regulator DJ572_10840 ENOG4105CHR reductase DJ572_10845 ENOG4105DVT helicase DJ572_10860 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) DJ572_10875 ENOG4108UKS UPF0398 protein DJ572_10885 ENOG4107X2U Inherit from COG: Exonuclease-like protein DJ572_10890 ENOG4108I5C dEAD DEAH box helicase DJ572_10940 ENOG4105BZ4 penicillin-binding protein DJ572_10950 ENOG4105CSM endonuclease III DJ572_10960 ENOG4105C5S asparaginyl-tRNA synthetase DJ572_10965 ENOG4105CHM Aminotransferase DJ572_10975 ENOG4105YAC DJ572_10980 ENOG4105DVT helicase DJ572_10985 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) DJ572_10995 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase DJ572_11000 ENOG4105DJ0 Poly(A) Polymerase DJ572_11005 ENOG4105CPK Glycosyl transferase (Group 1 DJ572_11010 ENOG4105FJR Lmbe family DJ572_11015 ENOG4108Z5K methylglyoxal synthase DJ572_11020 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) DJ572_11025 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase DJ572_11030 ENOG4108JYZ YitT family DJ572_11050 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) DJ572_11070 ENOG41068YB TPR repeat-containing protein DJ572_11075 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase DJ572_11085 ENOG4105CIH Imidazole acetol-phosphate transaminase DJ572_11095 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) DJ572_11100 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase DJ572_11110 ENOG4108I0Q anthranilate phosphoribosyltransferase DJ572_11115 ENOG4105CRQ synthase (Component I) DJ572_11120 ENOG4105KHN chorismate mutase DJ572_11125 ENOG4105D49 3-dehydroquinate synthase DJ572_11130 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase DJ572_11135 ENOG4105BZU Histidine kinase DJ572_11140 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) DJ572_11145 ENOG4105EAH synthase DJ572_11150 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DJ572_11155 ENOG4105XXQ heptaprenyl diphosphate synthase component I DJ572_11165 ENOG4105EUJ GTP cyclohydrolase i DJ572_11170 ENOG4105K70 DNA-binding protein DJ572_11175 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) DJ572_11190 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase DJ572_11195 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) DJ572_11200 ENOG41065D1 DJ572_11205 ENOG4105S2F DJ572_11220 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) DJ572_11225 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) DJ572_11230 ENOG4105CAT Cytidine monophosphate kinase DJ572_11245 ENOG4105MSI germination protein ypeb DJ572_11255 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) DJ572_11260 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase DJ572_11275 ENOG4107RGJ metallophosphoesterase DJ572_11290 ENOG4105I7S Abortive infection protein DJ572_11295 ENOG4105C9U ATP-dependent DNA helicase RecQ DJ572_11300 ENOG4105T7X DJ572_11310 ENOG4108SAX Membrane DJ572_11315 ENOG4108JQ1 Dehydrogenase DJ572_11320 ENOG4105FF2 Type I DHQase DJ572_11335 ENOG4105BZU Histidine kinase DJ572_11340 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ572_11345 ENOG4105CRE cytochrome C DJ572_11350 ENOG4107TWT Cytochrome c biogenesis protein DJ572_11360 ENOG4105FE9 pseudouridine synthase DJ572_11370 ENOG4108JIC nucleoside recognition domain protein DJ572_11375 ENOG4105DZ1 carboxypeptidase DJ572_11385 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) DJ572_11390 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) DJ572_11405 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) DJ572_11410 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) DJ572_11415 ENOG4108R6K riboflavin synthase, subunit alpha DJ572_11420 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) DJ572_11430 ENOG4105C3F Signal peptidase i DJ572_11440 ENOG4105VES Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DJ572_11465 ENOG4107ZE5 PPIases accelerate the folding of proteins DJ572_11475 ENOG4105PTM secreted protein DJ572_11480 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) DJ572_11490 ENOG4105G6R Stage v sporulation protein ae DJ572_11500 ENOG4105CZ3 stage V sporulation protein ad DJ572_11505 ENOG41090VF Stage v sporulation protein ac DJ572_11520 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ572_11525 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) DJ572_11530 ENOG41082AN stage II sporulation protein DJ572_11535 ENOG4105DZ1 carboxypeptidase DJ572_11540 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) DJ572_11545 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) DJ572_11550 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DJ572_11560 ENOG4105I3K Ferric uptake regulator, Fur family DJ572_11565 ENOG4105MZ9 stage II sporulation protein m DJ572_11580 ENOG4105DFD Na H antiporter DJ572_11585 ENOG4108IJ0 Aspartate ammonia-lyase DJ572_11590 ENOG4105HDK L-asparaginase DJ572_11595 ENOG4108IMY Transcriptional regulator DJ572_11605 ENOG4108YZ4 nudix hydrolase DJ572_11615 ENOG4105CPC Aldo Keto reductase DJ572_11635 ENOG4106HZJ DJ572_11640 ENOG4105RHY Pfam:UPF0157 DJ572_11645 ENOG4105KAC Antibiotic biosynthesis monooxygenase DJ572_11650 ENOG4108XET gCN5-related N-acetyltransferase DJ572_11660 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DJ572_11670 ENOG4105E5W Transporter DJ572_11680 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase DJ572_11695 ENOG4108IXY short-chain dehydrogenase reductase DJ572_11700 ENOG41069FQ Metallo-beta-lactamase superfamily DJ572_11705 ENOG4105II7 pyrroline-5-carboxylate reductase DJ572_11715 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DJ572_11725 ENOG410861F 50S ribosomal protein L33 DJ572_11730 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) DJ572_11735 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase DJ572_11740 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) DJ572_11745 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DJ572_11755 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) DJ572_11760 ENOG4108NA0 Uncharacterized conserved protein (COG2071) DJ572_11765 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) DJ572_11770 ENOG4108HNZ carboxyl transferase DJ572_11775 ENOG4108ZVT methylmalonyl-coA epimerase DJ572_11780 ENOG4108VZI ErfK ybiS ycfS ynhG family protein DJ572_11785 ENOG4108QEG Membrane DJ572_11790 ENOG4105CDA abc transporter atp-binding protein DJ572_11795 ENOG4105E5Q amino acid AbC transporter DJ572_11800 ENOG4108HW3 (ABC) transporter DJ572_11805 ENOG4108Y6J UPF0403 protein DJ572_11810 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) DJ572_11825 ENOG4105C7S Dehydrogenase DJ572_11830 ENOG4105CPP Dehydrogenase, E1 component DJ572_11845 ENOG4105CKM Branched-chain carboxylic acid kinase DJ572_11850 ENOG4107RDP Dehydrogenase DJ572_11860 ENOG4108JUB Transcriptional regulator DJ572_11865 ENOG4106CCJ Protein of unknown function (DUF2627) DJ572_11870 ENOG4105CR4 methylisocitrate lyase DJ572_11875 ENOG4105DXD 2-methylcitrate dehydratase DJ572_11885 ENOG4105C1G acyl-Coa dehydrogenase DJ572_11890 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DJ572_11900 ENOG4108QXE glycerophosphoryl diester phosphodiesterase DJ572_11905 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DJ572_11915 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DJ572_11920 ENOG4107QQR Sporulation DJ572_11925 ENOG4105S1Z Stage IV sporulation protein B DJ572_11930 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) DJ572_11935 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) DJ572_11940 ENOG4105DX0 Hemolysin A DJ572_11950 ENOG4105CTB Polyprenyl synthetase DJ572_11955 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) DJ572_11960 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) DJ572_11965 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) DJ572_11970 ENOG4105M7K Involved in the transcription termination process (By similarity) DJ572_11975 ENOG4108ZSR alkaline shock protein DJ572_11980 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DJ572_12000 ENOG410644B Stage III sporulation protein af DJ572_12010 ENOG4105KQ4 Stage iii sporulation protein ad DJ572_12015 ENOG4108CQH stage III sporulation protein AC DJ572_12020 ENOG4105KR5 Stage iii sporulation protein DJ572_12025 ENOG4105CD2 stage iii sporulation protein aa DJ572_12035 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) DJ572_12040 ENOG4105DC7 peptidase M24 DJ572_12045 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) DJ572_12055 ENOG4105CBJ Metal-dependent enzyme DJ572_12070 ENOG4105KST dependent repressor DJ572_12075 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) DJ572_12080 ENOG4105WZW rhodanese family DJ572_12085 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor DJ572_12090 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor DJ572_12095 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) DJ572_12100 ENOG4105C0D helicase DJ572_12115 ENOG4108IMY Transcriptional regulator DJ572_12125 ENOG4105VFR signal peptidase DJ572_12180 ENOG41080XP Cbs domain DJ572_12190 ENOG4105C37 (CBS) domain DJ572_12215 ENOG4105C5X domain protein DJ572_12240 ENOG4105E0M Sulfatase DJ572_12255 ENOG4107ZXI Rhomboid family DJ572_12265 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase DJ572_12270 ENOG4105WDJ 50S ribosomal protein L33 DJ572_12290 ENOG41068DG YceG-like family DJ572_12295 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) DJ572_12300 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) DJ572_12305 ENOG4105E2Z phosphate ABC transporter (Permease DJ572_12310 ENOG4105C8U phosphate abc transporter DJ572_12315 ENOG4105CVA phosphate DJ572_12320 ENOG4107RF6 penicillin-binding protein DJ572_12330 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DJ572_12335 ENOG4105SXS Protein of unknown function (DUF456) DJ572_12350 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) DJ572_12355 ENOG41063Y9 DJ572_12360 ENOG4108U5J '-nucleotidase DJ572_12365 ENOG4105N80 Ferric uptake regulator, Fur family DJ572_12370 ENOG4108JYZ YitT family DJ572_12375 ENOG41069ZM Protein of unknown function (DUF2624) DJ572_12380 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) DJ572_12395 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) DJ572_12400 ENOG4105EGD dinuclear metal center protein, YbgI family DJ572_12420 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ572_12425 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) DJ572_12430 ENOG41082VT Uncharacterized BCR, YaiI/YqxD family COG1671 DJ572_12435 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) DJ572_12445 ENOG4105C38 Glycyl-tRNA synthetase beta subunit DJ572_12450 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit DJ572_12455 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) DJ572_12465 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) DJ572_12470 ENOG4105KG3 cytidine deaminase DJ572_12475 ENOG4107YR5 Diacylglycerol kinase DJ572_12480 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) DJ572_12485 ENOG4105CTJ Metal Dependent Phosphohydrolase DJ572_12490 ENOG4105C9A Phoh family DJ572_12495 ENOG4105EI1 sporulation protein yqfd DJ572_12500 ENOG41068P3 sporulation protein YqfC DJ572_12510 ENOG4105DI5 UPF0365 protein DJ572_12515 ENOG4105F7J membrane-bound serine protease DJ572_12520 ENOG4105KTH gatB Yqey DJ572_12535 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DJ572_12540 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) DJ572_12545 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) DJ572_12555 ENOG4105CFG Acts as a chaperone (By similarity) DJ572_12560 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ DJ572_12565 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) DJ572_12570 ENOG4105CSA Coproporphyrinogen iii oxidase DJ572_12575 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) DJ572_12585 ENOG4108ZRV stage ii sporulation protein p DJ572_12590 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) DJ572_12595 ENOG41082YS Binds directly to 16S ribosomal RNA DJ572_12600 ENOG4105TQK DNA polymerase iii, delta' subunit DJ572_12610 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 DJ572_12615 ENOG4108UK2 deaminase DJ572_12620 ENOG4105KQC Competence protein DJ572_12630 ENOG4108D32 Methyltransferase DJ572_12640 ENOG4108WF2 Metal Dependent Phosphohydrolase DJ572_12645 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) DJ572_12650 ENOG410812S Rna-binding protein DJ572_12655 ENOG4105E2X shikimate dehydrogenase DJ572_12660 ENOG4105CQW ribosome biogenesis GTPase YqeH DJ572_12665 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase DJ572_12680 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ572_12685 ENOG41080BT SNARE associated Golgi DJ572_12700 ENOG4105WFK nuclease DJ572_12705 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ572_12710 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ572_12715 ENOG4107Y5K Resolvase DJ572_12750 ENOG4105KVH Transcriptional regulator DJ572_12755 ENOG4108DBC nitroreductase DJ572_12775 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase DJ572_12840 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) DJ572_12855 ENOG4108SWU Histidine kinase DJ572_12860 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ572_12865 ENOG4105DHF Membrane DJ572_12870 ENOG4108UYN gCN5-related N-acetyltransferase DJ572_12875 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein DJ572_12880 ENOG41068VA DJ572_12885 ENOG41087NI Sulfite exporter TauE/SafE DJ572_12890 ENOG4105VFE sira family DJ572_12895 ENOG4107TPS domain protein DJ572_12905 ENOG4105VFE sira family DJ572_12910 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase DJ572_12915 ENOG4105XTG Pfam:DUF156 DJ572_12930 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein DJ572_12945 ENOG41090E6 transcriptional regulator MERR family DJ572_12960 ENOG4105C37 (CBS) domain DJ572_12975 ENOG410825D TRANSCRIPTIONal REGULATOR, LysR family DJ572_12980 ENOG4105H3G oxidoreductase DJ572_12985 ENOG4105PGM cation diffusion facilitator family transporter DJ572_12990 ENOG41090U3 tautomerase DJ572_13010 ENOG4105KMT branched-chain amino acid DJ572_13015 ENOG4108UMN azlc family DJ572_13020 ENOG4108ZRZ Transcriptional regulator (AsnC family) DJ572_13045 ENOG41064BW Protein of unknown function (DUF2568) DJ572_13060 ENOG41075D4 Aminoglycoside 6-adenylyltransferase DJ572_13065 ENOG4105EA8 2-Nitropropane dioxygenase DJ572_13080 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) DJ572_13095 ENOG4108MEK Metal-binding protein YodA DJ572_13100 ENOG410904A RNA polymerase DJ572_13105 ENOG4105CPC Aldo Keto reductase DJ572_13115 ENOG4108KAM Transcriptional regulator DJ572_13120 ENOG4105C7F AcnD-accessory protein PrpF DJ572_13125 ENOG41083Q9 chitosanase DJ572_13130 ENOG4105X5K response regulator receiver protein DJ572_13135 ENOG4108VQT Alpha beta hydrolase fold protein DJ572_13140 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein DJ572_13145 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein DJ572_13150 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase DJ572_13160 ENOG4105PGS Spore coat protein DJ572_13165 ENOG4105E2A Dehydrogenase DJ572_13180 ENOG4105VUF Transcriptional regulator DJ572_13190 ENOG4105DQ4 alcohol dehydrogenase DJ572_13195 ENOG4108Z0Z intracellular protease Pfpi family DJ572_13200 ENOG4108HKT sucrose-6-phosphate hydrolase DJ572_13205 ENOG4105F3R pts system mannose fructose sorbose family iid DJ572_13210 ENOG4105ETZ PTS System DJ572_13215 ENOG4108IQ3 PTS system DJ572_13220 ENOG4105YHU PTS system DJ572_13225 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DJ572_13230 ENOG4105C85 amino acid DJ572_13235 ENOG4105N14 lysine exporter protein LysE YggA DJ572_13240 ENOG4108NGU Transcriptional regulator DJ572_13245 ENOG4105JVQ RNA Polymerase DJ572_13250 ENOG4108P49 AntiSigma factor DJ572_13255 ENOG4105EXC Acyl-transferase DJ572_13260 ENOG4105WDR DJ572_13265 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DJ572_13270 ENOG41082JN Transcriptional regulator DJ572_13285 ENOG4105TMB Formate nitrite transporter DJ572_13290 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) DJ572_13295 ENOG4108JB9 formate dehydrogenase DJ572_13310 ENOG4105C28 cystathionine DJ572_13325 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) DJ572_13340 ENOG4107XRG penicillin-binding protein DJ572_13345 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) DJ572_13350 ENOG4105DBI uridine monophosphokinase DJ572_13355 ENOG4105CFP Peptidase U32 DJ572_13360 ENOG4105XYU peptidase (U32 family) DJ572_13365 ENOG4108VQJ O-methyltransferase DJ572_13370 ENOG4105HHA aminodeoxychorismate lyase DJ572_13375 ENOG4105VPH UPF0473 protein DJ572_13380 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) DJ572_13385 ENOG4105VBH UPF0297 protein DJ572_13390 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DJ572_13395 ENOG4105C02 permease DJ572_13400 ENOG4105CDA abc transporter atp-binding protein DJ572_13405 ENOG4105CT1 (ABC) transporter DJ572_13410 ENOG4105EAD ABC transporter DJ572_13415 ENOG4105DRP amino acid AbC transporter DJ572_13425 ENOG41060CR DJ572_13435 ENOG4105C7H Helicase, RecD TraA family DJ572_13445 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) DJ572_13450 ENOG4105C3J Cysteine desulfurase DJ572_13460 ENOG4105D1H recombination factor protein RarA DJ572_13465 ENOG4105CUZ uba thif-type nad fad binding protein DJ572_13475 ENOG4105C9M aspartyl-trna synthetase DJ572_13480 ENOG4105CUT histidyl-tRNA synthetase DJ572_13490 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DJ572_13500 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DJ572_13505 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) DJ572_13510 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) DJ572_13515 ENOG41067VP Protein of unknown function (DUF1049) DJ572_13520 ENOG4105NCW Trka-c domain protein DJ572_13525 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) DJ572_13535 ENOG4105CKP Polysaccharide Biosynthesis Protein DJ572_13540 ENOG4108QG2 Membrane DJ572_13545 ENOG4105NAP DJ572_13550 ENOG4105VIE preprotein translocase, subunit YajC DJ572_13555 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) DJ572_13560 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) DJ572_13565 ENOG41061AI Protein of unknown function (DUF2905) DJ572_13570 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) DJ572_13575 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) DJ572_13585 ENOG4105IE8 Alpha-ketoglutarate permease DJ572_13590 ENOG4105CK5 oxidoreductase DJ572_13610 ENOG4105BZG amino acid carrier protein DJ572_13625 ENOG4106678 morphogenetic protein associated with SpoVID DJ572_13630 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) DJ572_13635 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase DJ572_13640 ENOG4108IYU L-aspartate oxidase DJ572_13655 ENOG4105CQC Prephenate dehydratase DJ572_13660 ENOG41090I5 UPF0735 ACT domain-containing protein DJ572_13665 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control DJ572_13675 ENOG4105K46 50S ribosomal protein l27 DJ572_13680 ENOG4105X36 (ribosomal) protein DJ572_13685 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) DJ572_13700 ENOG4107QMS site-determining protein DJ572_13705 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) DJ572_13710 ENOG4105YHC Rod shape-determining protein MreD DJ572_13715 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) DJ572_13720 ENOG4105DFF Rod shape-determining protein mreb DJ572_13725 ENOG4105W5Q DNA repair protein (RadC DJ572_13730 ENOG4108Z03 MAF-like protein DJ572_13740 ENOG4106A3R peptidase DJ572_13745 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase DJ572_13750 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) DJ572_13760 ENOG4106AR7 Spore coat protein DJ572_13765 ENOG41068KH stage VI sporulation protein D DJ572_13770 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase DJ572_13775 ENOG4105D52 delta-aminolevulinic acid dehydratase DJ572_13785 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) DJ572_13795 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) DJ572_13805 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) DJ572_13810 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) DJ572_13815 ENOG4108IUQ atp-dependent protease DJ572_13820 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) DJ572_13825 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation DJ572_13835 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) DJ572_13840 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) DJ572_13845 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DJ572_13850 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) DJ572_13855 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase DJ572_13860 ENOG4108ZP8 Acetolactate synthase small subunit DJ572_13865 ENOG4105C7K acetolactate synthase DJ572_13875 ENOG4105I4A GCN5-related N-acetyltransferase DJ572_13880 ENOG4107KM7 Heat induced stress protein YflT DJ572_13890 ENOG4105M59 Phosphodiesterase, mj0936 family DJ572_13895 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) DJ572_13900 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) DJ572_13905 ENOG4108XJQ germination protein DJ572_13910 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) DJ572_13915 ENOG41067TZ transcriptional regulator, MarR family DJ572_13920 ENOG4105PFC Transcriptional regulator DJ572_13930 ENOG4105E33 succinate dehydrogenase DJ572_13940 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit DJ572_13950 ENOG4105CFH Aspartokinase DJ572_13960 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) DJ572_13965 ENOG4105K63 Thioredoxin DJ572_13975 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) DJ572_13980 ENOG4105C10 Electron transfer flavoprotein DJ572_13985 ENOG4105BZJ Electron transfer flavoprotein DJ572_13990 ENOG41060WC Enoyl-CoA hydratase DJ572_13995 ENOG4107Z3H Transcriptional regulator, TetR family DJ572_14000 ENOG4105CEY Amp-dependent synthetase and ligase DJ572_14010 ENOG4105C98 muts2 protein DJ572_14015 ENOG4105DCG PHP domain protein DJ572_14030 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) DJ572_14035 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) DJ572_14040 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) DJ572_14050 ENOG4108RWN rrna methyltransferase DJ572_14055 ENOG41067MF small acid-soluble spore protein DJ572_14065 ENOG4105CQB FAD linked oxidase domain protein DJ572_14070 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) DJ572_14090 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) DJ572_14095 ENOG4105DRS transport system, permease DJ572_14110 ENOG4108MDK Dehydrogenase DJ572_14120 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase DJ572_14125 ENOG4105EF1 ribulokinase DJ572_14135 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase DJ572_14140 ENOG4105CN9 Peptidase m42 family protein DJ572_14150 ENOG410696E Membrane DJ572_14155 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) DJ572_14160 ENOG4105VJV 50s ribosomal protein L35 DJ572_14165 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) DJ572_14175 ENOG41067MG lrgb family DJ572_14185 ENOG4105DY9 regulatoR DJ572_14190 ENOG4108HRK Histidine kinase DJ572_14195 ENOG4105U0R haloacid dehalogenase-like hydrolase DJ572_14200 ENOG4105C22 threonyL-tRNA synthetase DJ572_14205 ENOG4108TDW sporulation protein YtxC DJ572_14225 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) DJ572_14230 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) DJ572_14235 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase DJ572_14240 ENOG4105KVH Transcriptional regulator DJ572_14245 ENOG4105F27 Major Facilitator DJ572_14250 ENOG4105CV8 reductase DJ572_14255 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) DJ572_14265 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) DJ572_14270 ENOG4105C2M dna polymerase I DJ572_14275 ENOG4105BZU Histidine kinase DJ572_14280 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ572_14290 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DJ572_14295 ENOG4108HMX isocitrate dehydrogenase (NADP) DJ572_14300 ENOG4105BZN citrate synthase DJ572_14310 ENOG4108REF Sporulation integral membrane protein ytvi DJ572_14315 ENOG4105FS0 cytoplasmic membrane protein DJ572_14320 ENOG4105CA9 Pyruvate kinase DJ572_14325 ENOG4105CTQ phosphohexokinase DJ572_14335 ENOG4108IEY Carboxyl transferase domain DJ572_14340 ENOG4105C6K Malic enzyme DJ572_14345 ENOG4105C0B DNA polymerase III (alpha subunit) DJ572_14350 ENOG4105VV2 DJ572_14360 ENOG4106EVM DJ572_14365 ENOG4105SFS phosphoesterase RecJ domain protein DJ572_14380 ENOG410635A Membrane DJ572_14385 ENOG4105CH2 amidohydrolase DJ572_14405 ENOG4105DEN Luciferase family DJ572_14410 ENOG4105CDA abc transporter atp-binding protein DJ572_14435 ENOG4108XSB acetyltransferase, (GNAT) family DJ572_14440 ENOG4108KSA LysR family transcriptional regulator DJ572_14445 ENOG4105E8R UPF0173 metal-dependent hydrolase DJ572_14460 ENOG4105CH7 arginosuccinase DJ572_14465 ENOG4105CDH Citrulline--aspartate ligase DJ572_14470 ENOG4105EPU Molybdenum cofactor synthesis domain protein DJ572_14475 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) DJ572_14490 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) DJ572_14495 ENOG4105KBJ sporulation protein ytfj DJ572_14505 ENOG4105VK3 rdd domain containing protein DJ572_14510 ENOG4105D07 Signal peptide peptidase, SppA DJ572_14515 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) DJ572_14520 ENOG4105EFZ amidohydrolase DJ572_14525 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DJ572_14560 ENOG4105U5Y Transcriptional regulator DJ572_14570 ENOG4105BZU Histidine kinase DJ572_14580 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) DJ572_14585 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) DJ572_14600 ENOG4105F1V Acetoin utilization protein DJ572_14605 ENOG4105W87 Cbs domain DJ572_14610 ENOG4105DGU Histone deacetylase DJ572_14615 ENOG4105ER2 Ompa motb domain protein DJ572_14620 ENOG4107R0U MotA TolQ exbB proton channel DJ572_14625 ENOG4105ETE Transcriptional regulator (LacI family DJ572_14630 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase DJ572_14650 ENOG4105DFU Cell wall formation (By similarity) DJ572_14660 ENOG4108VDD TRNA binding domain protein DJ572_14675 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ DJ572_14690 ENOG4105C6K Malic enzyme DJ572_14695 ENOG4105C8F Beta-lactamase domain protein DJ572_14700 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) DJ572_14710 ENOG4108V15 phosphotransferase enzyme family DJ572_14715 ENOG4108IUM Glycogen debranching enzyme DJ572_14730 ENOG4107F58 2'-5' rna ligase DJ572_14735 ENOG4105C6T cysteine synthase DJ572_14740 ENOG4107QSE Dipeptidase DJ572_14745 ENOG4105C7N Xanthine uracil vitamin C permease DJ572_14760 ENOG4105YW5 deoR family transcriptional regulator DJ572_14775 ENOG4105CBX hi0933 family DJ572_14780 ENOG4105C94 Transporter DJ572_14790 ENOG4105MU9 integral membrane protein DJ572_14795 ENOG4105DDC Oxidoreductase domain protein DJ572_14805 ENOG4105F5H Glycosyl Hydrolase Family 88 DJ572_14815 ENOG41075H3 AraC family transcriptional regulator DJ572_14825 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component DJ572_14835 ENOG4106A3M Cytochrome p-450 DJ572_14840 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) DJ572_14850 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DJ572_14855 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DJ572_14865 ENOG4105NTD Inherit from COG: Hydrolase DJ572_14880 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component DJ572_14885 ENOG4105I1K ABC transporter DJ572_14895 ENOG41085GJ domain protein DJ572_14900 ENOG4105C8T Leucyl-tRNA synthetase DJ572_14910 ENOG4105BZU Histidine kinase DJ572_14915 ENOG410605W Major Facilitator DJ572_14920 ENOG4106UBQ DJ572_14930 ENOG4105C19 ABC transporter DJ572_14935 ENOG4105EWM Histidine kinase DJ572_14945 ENOG4107R34 abc transporter permease protein DJ572_14950 ENOG4105C19 ABC transporter DJ572_14965 ENOG4105DVE abc transporter atp-binding protein DJ572_14970 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DJ572_14980 ENOG4105N5T Radical SAM Protein DJ572_14995 ENOG4105E8V Alpha Beta Hydrolase Fold protein DJ572_15000 ENOG4108Z0R Transferase DJ572_15005 ENOG4105C85 amino acid DJ572_15010 ENOG4105CAQ asparagine synthetase DJ572_15015 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP DJ572_15020 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase DJ572_15035 ENOG4105D2X ABC transporter substrate-binding protein DJ572_15045 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component DJ572_15060 ENOG4108RMU ferritin dps family protein DJ572_15075 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) DJ572_15080 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) DJ572_15085 ENOG4108V2W Carbonate dehydratase DJ572_15110 ENOG4105CC5 ABC transporter DJ572_15115 ENOG4105CC5 ABC transporter DJ572_15120 ENOG4105DIK (ABC) transporter DJ572_15125 ENOG4105DSE periplasmic solute binding protein DJ572_15130 ENOG4105DTQ mandelate racemase muconate lactonizing DJ572_15135 ENOG4105CEY Amp-dependent synthetase and ligase DJ572_15140 ENOG4108IPT Naphthoate synthase DJ572_15145 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) DJ572_15150 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) DJ572_15155 ENOG4105E4F Isochorismate synthase DJ572_15175 ENOG4108IAJ Nad-dependent epimerase dehydratase DJ572_15180 ENOG4107SBE Glycosyl transferase (Group 1 DJ572_15195 ENOG4107SBE Glycosyl transferase (Group 1 DJ572_15200 ENOG4108KS4 Spore coat protein DJ572_15215 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) DJ572_15225 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) DJ572_15355 ENOG4105N67 Proton-coupled thiamine transporter YuaJ DJ572_15360 ENOG4105VRR gCN5-related N-acetyltransferase DJ572_15365 ENOG4105DZ6 Band 7 protein DJ572_15375 ENOG4106DF1 DJ572_15380 ENOG4108VNY MOSC domain protein DJ572_15385 ENOG4108JB8 alcohol dehydrogenase DJ572_15390 ENOG4105C26 Dehydrogenase DJ572_15395 ENOG4105TRT Transcriptional regulator DJ572_15410 ENOG4105CZN Potassium uptake protein DJ572_15415 ENOG4107I77 yiaA/B two helix domain DJ572_15420 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj DJ572_15440 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DJ572_15450 ENOG4105EE0 oxidoreductase DJ572_15455 ENOG4105DKG l-rhamnose isomerase DJ572_15460 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) DJ572_15465 ENOG4105DET Rhamnulokinase DJ572_15470 ENOG4105E98 transcriptional regulator DeoR family DJ572_15485 ENOG4105C8Q Methyl-accepting chemotaxis DJ572_15490 ENOG4105C8Q Methyl-accepting chemotaxis DJ572_15495 ENOG4105C8Q Methyl-accepting chemotaxis DJ572_15500 ENOG4105C8Q Methyl-accepting chemotaxis DJ572_15515 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme DJ572_15525 ENOG4105C37 (CBS) domain DJ572_15540 ENOG4107PBV potassium channel DJ572_15545 ENOG4107PBV potassium channel DJ572_15560 ENOG4107QYV phosphohexose isomerase DJ572_15570 ENOG4107QW4 alcohol dehydrogenase DJ572_15575 ENOG4105WG9 Conserved Protein DJ572_15585 ENOG4105CHM Aminotransferase DJ572_15590 ENOG4108ZB6 transcriptional regulator AsnC family DJ572_15595 ENOG4108MUZ hydrolase DJ572_15605 ENOG4105C87 Aminotransferase class I and II DJ572_15610 ENOG4108HGU Histidine kinase DJ572_15615 ENOG4105Y38 Kinase-associated protein B DJ572_15635 ENOG4105BZ4 penicillin-binding protein DJ572_15640 ENOG4105KIR Thiol-disulfide oxidoreductase dcc DJ572_15655 ENOG4108MRH transcriptional regulatory protein DJ572_15660 ENOG4105DIH basic membrane DJ572_15665 ENOG4108JQ9 ABC transporter DJ572_15670 ENOG4105UIB (ABC) transporter DJ572_15690 ENOG4105D65 subunit l DJ572_15695 ENOG4105HC0 Na H antiporter DJ572_15700 ENOG4108ZE9 Monovalent cation H antiporter subunit C DJ572_15705 ENOG4108JPZ Monovalent cation H antiporter subunit D DJ572_15710 ENOG4105SC1 monovalent cation H antiporter subunit E DJ572_15720 ENOG4105KJM monovalent cation h antiporter subunit g DJ572_15725 ENOG4105KA0 thioesterase Superfamily protein DJ572_15735 ENOG4105BZU Histidine kinase DJ572_15760 ENOG4105D58 Diguanylate phosphodiesterase DJ572_15765 ENOG4105DAP Nicotinate phosphoribosyltransferase DJ572_15790 ENOG4105C02 permease DJ572_15810 ENOG410904N short-chain dehydrogenase reductase DJ572_15845 ENOG4108K8K Transcriptional regulator DJ572_15850 ENOG4105DCF alanine dehydrogenase DJ572_15860 ENOG4105WQT MbtH domain protein DJ572_15865 ENOG4105CEY Amp-dependent synthetase and ligase DJ572_15870 ENOG4105WQI isochorismatase DJ572_15875 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase DJ572_15880 ENOG4105E4F Isochorismate synthase DJ572_15885 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase DJ572_15890 ENOG4105NIV Esterase DJ572_15910 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) DJ572_15920 ENOG41069ER domain protein DJ572_15935 ENOG4105CEP NADH dehydrogenase DJ572_15940 ENOG4105CAY ferredoxin--nadp reductase DJ572_15960 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 DJ572_15965 ENOG4108YX9 iron--sulfur cluster insertion protein erpA DJ572_15980 ENOG4105ZKE UPF0349 protein DJ572_15995 ENOG41083MR nifu domain-containing protein DJ572_16000 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein DJ572_16005 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) DJ572_16010 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) DJ572_16015 ENOG4105D6E homoserine dehydrogenase DJ572_16025 ENOG4108W5N phosphatidylglycerophosphatase a DJ572_16030 ENOG4105D4U had-superfamily hydrolase, subfamily iia DJ572_16040 ENOG4105MMD transcriptional regulator DJ572_16045 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DJ572_16050 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) DJ572_16055 ENOG4105FAA peptidase M23 DJ572_16060 ENOG4108YTE sporulation protein YunB DJ572_16065 ENOG4105KZD Domain of unknown function (DUF1805) DJ572_16070 ENOG4107R8B 5'-nucleotidase DJ572_16080 ENOG4105I3N Conserved Protein DJ572_16090 ENOG4105CD3 dihydroorotase DJ572_16095 ENOG4105G9B Transcriptional regulator DJ572_16110 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) DJ572_16115 ENOG4105VT2 5-hydroxyisourate hydrolase DJ572_16125 ENOG4107YV9 domain protein DJ572_16130 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding DJ572_16145 ENOG4105XRQ Xanthine dehydrogenase accessory factor DJ572_16150 ENOG4105C5R Aminotransferase DJ572_16160 ENOG4108K8S endonuclease I DJ572_16165 ENOG4108IJ9 (ABC) transporter DJ572_16170 ENOG4105FDP GntR family transcriptional regulator DJ572_16175 ENOG4108KPW sugar kinase DJ572_16180 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component DJ572_16185 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component DJ572_16190 ENOG4105XN3 extracellular solute-binding protein family 1 DJ572_16195 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine DJ572_16200 ENOG4105PKS Excinuclease abc c subunit domain protein DJ572_16205 ENOG4107VFR oxidoreductase DJ572_16220 ENOG4105DIW FeS assembly protein SUFB DJ572_16225 ENOG4108UNV SUF system FeS assembly protein, NifU family DJ572_16230 ENOG4105C9B Cysteine desulfurase DJ572_16235 ENOG4105JRK feS assembly protein SufD DJ572_16240 ENOG4105C3K feS assembly ATPase SufC DJ572_16260 ENOG4105D01 (LipO)protein DJ572_16265 ENOG4108UMI ABC transporter, permease DJ572_16270 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DJ572_16295 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) DJ572_16300 ENOG41080E8 Transcriptional regulator, Spx MgsR family DJ572_16305 ENOG4105C1G acyl-Coa dehydrogenase DJ572_16310 ENOG4105CHU acetyl-coa acetyltransferase DJ572_16340 ENOG41067TZ transcriptional regulator, MarR family DJ572_16345 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ572_16350 ENOG4105MDS 4-oxalocrotonate tautomerase DJ572_16360 ENOG4105EGI Transcriptional regulator DJ572_16370 ENOG4105E0A ABC, transporter DJ572_16385 ENOG4105E1F short-chain dehydrogenase reductase DJ572_16390 ENOG4105HUF DNA protection during starvation protein DJ572_16395 ENOG4105C0H protease DJ572_16405 ENOG4105F3H Histidine kinase DJ572_16415 ENOG41067SE Tetr family transcriptional regulator DJ572_16420 ENOG4105C9Q fumarate hydratase class II DJ572_16445 ENOG4105WH1 Two component transcriptional regulator luxr family DJ572_16450 ENOG4105ENE Histidine kinase DJ572_16465 ENOG41087YS Phage shock protein A DJ572_16480 ENOG4108WBT adenosyltransferase DJ572_16485 ENOG4105E0A ABC, transporter DJ572_16490 ENOG4105EHG Permease protein DJ572_16495 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) DJ572_16500 ENOG4105EWI Short-chain dehydrogenase reductase Sdr DJ572_16505 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein DJ572_16515 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ572_16525 ENOG4106DF4 Sigma-70, region 4 DJ572_16535 ENOG4105F0F Oxalate decarboxylase DJ572_16545 ENOG4107RBB ABC transporter, permease DJ572_16550 ENOG4105C19 ABC transporter DJ572_16555 ENOG4108WMK Efflux transporter RND family MFP subunit DJ572_16560 ENOG4105E0A ABC, transporter DJ572_16565 ENOG4105EHG Permease protein DJ572_16570 ENOG4105DQ5 transport system permease protein DJ572_16580 ENOG4105D5Q Arginine ornithine antiporter DJ572_16595 ENOG4107K5X Membrane-bound metal-dependent hydrolase DJ572_16600 ENOG4107QZ2 Sulfatase DJ572_16605 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family DJ572_16610 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DJ572_16615 ENOG4105E0C molybdate abc transporter DJ572_16630 ENOG4105EEQ Na H antiporter DJ572_16635 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) DJ572_16640 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DJ572_16645 ENOG4105EEM helicase DJ572_16650 ENOG4105EN6 Membrane DJ572_16660 ENOG4107ZQN disulfide bond DJ572_16665 ENOG4105C59 p-type ATPase DJ572_16670 ENOG4105C59 p-type ATPase DJ572_16675 ENOG410681U heavy metal transport detoxification protein DJ572_16680 ENOG4105VPX protein, conserved in bacteria DJ572_16685 ENOG4105D9R oxidoreductase DJ572_16690 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DJ572_16695 ENOG4105ME7 Membrane DJ572_16700 ENOG4105RXJ DJ572_16705 ENOG4105KPY Small multidrug resistance protein DJ572_16710 ENOG4105KBX Transcriptional regulator, TetR family DJ572_16715 ENOG4105EWI Short-chain dehydrogenase reductase Sdr DJ572_16725 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) DJ572_16730 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) DJ572_16740 ENOG4105XZU Preprotein translocase, subunit SecG DJ572_16765 ENOG4105KVH Transcriptional regulator DJ572_16770 ENOG4105C8Q Methyl-accepting chemotaxis DJ572_16775 ENOG4105R40 Glycine betaine carnitine choline DJ572_16780 ENOG4108HQR Glycine betaine DJ572_16785 ENOG4105E90 ABC transporter DJ572_16790 ENOG4108IJ8 ABC transporter DJ572_16795 ENOG4107HG4 Transcriptional regulator DJ572_16800 ENOG4105R40 Glycine betaine carnitine choline DJ572_16805 ENOG4108HQR Glycine betaine DJ572_16810 ENOG4105E90 ABC transporter DJ572_16815 ENOG4108IJ8 ABC transporter DJ572_16820 ENOG4107HG4 Transcriptional regulator DJ572_16825 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein DJ572_16830 ENOG4108QCI YvbH-like oligomerisation region DJ572_16840 ENOG4105T65 Membrane-associated protein DJ572_16845 ENOG4108W0I acetyltransferase DJ572_16850 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) DJ572_16855 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DJ572_16860 ENOG4105CP7 Triose-phosphate isomerase DJ572_16865 ENOG4105BZA Phosphoglycerate kinase DJ572_16870 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase DJ572_16885 ENOG4105CMD Transcriptional regulator, GntR family DJ572_16890 ENOG4105DEN Luciferase family DJ572_16900 ENOG4105GZI Transcriptional regulator DJ572_16905 ENOG4107RT3 EamA-like transporter family DJ572_16915 ENOG4105VRS hydrolase family 18 DJ572_16920 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) DJ572_16925 ENOG4107QR9 Iron-sulfur cluster binding protein DJ572_16930 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) DJ572_16940 ENOG4105BZU Histidine kinase DJ572_16945 ENOG4105KCT ABC transporter DJ572_16950 ENOG4108M15 ABC transporter DJ572_16955 ENOG4107R6F Alpha Beta Hydrolase Fold protein DJ572_16960 ENOG4108MJI response regulator DJ572_16975 ENOG4105EG2 ABC transporter, permease DJ572_16985 ENOG4107FKK extracellular solute-binding protein family 1 DJ572_16995 ENOG4105JXH GntR family transcriptional regulator DJ572_17000 ENOG4105DAA L-lactate DJ572_17005 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ572_17015 ENOG4108ZPC Polysaccharide pyruvyl transferase DJ572_17020 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase DJ572_17025 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family DJ572_17030 ENOG4105D3Q Sugar transferase DJ572_17040 ENOG4105K64 Glycosyl transferase, family 2 DJ572_17050 ENOG4107QRS glycosyltransferase group 2 family protein DJ572_17055 ENOG41068W6 Capsular polysaccharide biosynthesis protein DJ572_17060 ENOG4108KMV Glycosyl transferase (Group 1 DJ572_17065 ENOG4105K64 Glycosyl transferase, family 2 DJ572_17070 ENOG4108PQP glycosyl transferase group 1 DJ572_17080 ENOG4108QV3 biosynthesis protein DJ572_17085 ENOG4105HTX biosynthesis protein DJ572_17105 ENOG4105PY6 Phenolic acid decarboxylase DJ572_17110 ENOG4105NI3 Protein of unknown function (DUF3237) DJ572_17120 ENOG4105FQP Beta-lactamase DJ572_17125 ENOG4105EDQ levansucrase EC 2.4.1.10 DJ572_17130 ENOG4108HKT sucrose-6-phosphate hydrolase DJ572_17135 ENOG4107QTZ amino acid DJ572_17160 ENOG4105DNP FAD linked oxidase domain protein DJ572_17165 ENOG4105IRW patatin-like phospholipase family protein DJ572_17175 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DJ572_17180 ENOG4107URF beta-phospho-glucomutase DJ572_17185 ENOG4105CG3 alpha amylase, catalytic region DJ572_17200 ENOG4105EG2 ABC transporter, permease DJ572_17205 ENOG4105D56 permease protein DJ572_17210 ENOG4107FKK extracellular solute-binding protein family 1 DJ572_17215 ENOG4108IUK alpha amylase, catalytic DJ572_17220 ENOG4105FKQ transcriptional regulator DJ572_17225 ENOG4108URH decarboxylase DJ572_17230 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain DJ572_17235 ENOG4105CHH sulfate transporter DJ572_17240 ENOG4108V2W Carbonate dehydratase DJ572_17245 ENOG4105C5I Dehydrogenase DJ572_17255 ENOG4105C19 ABC transporter DJ572_17260 ENOG4105EWM Histidine kinase DJ572_17270 ENOG4107A6P DJ572_17275 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase DJ572_17280 ENOG4105KRI phosphocarrier protein (HPr DJ572_17285 ENOG4105CIE May be required for sporulation (By similarity) DJ572_17290 ENOG4105CHW UPF0052 protein DJ572_17295 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) DJ572_17300 ENOG4108Z4K mutator MutT protein DJ572_17305 ENOG4105C3M thioredoxin reductase DJ572_17320 ENOG4105BZ1 (ABC) transporter DJ572_17330 ENOG4106FGC DJ572_17340 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase DJ572_17345 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) DJ572_17350 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase DJ572_17355 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) DJ572_17360 ENOG4105ECC imidazole-glycerol-phosphate dehydratase DJ572_17365 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) DJ572_17370 ENOG4107RN8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) DJ572_17375 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) DJ572_17385 ENOG4108E16 pectate lyase DJ572_17390 ENOG4108S4C acetyltransferase DJ572_17395 ENOG4107XGZ Hydrolase DJ572_17400 ENOG4105HKU nucleoside recognition domain-containing protein DJ572_17405 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) DJ572_17410 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) DJ572_17415 ENOG4105CE4 GlcNAc 6-P deacetylase DJ572_17420 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) DJ572_17425 ENOG4105FDP GntR family transcriptional regulator DJ572_17430 ENOG41088CQ domain protein DJ572_17445 ENOG410625E DJ572_17460 ENOG41086DT Membrane protein of unknown function DJ572_17465 ENOG41067S9 phage shock protein C, PspC DJ572_17470 ENOG4108PY7 DJ572_17485 ENOG4105I03 Flagellin DJ572_17490 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DJ572_17495 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) DJ572_17510 ENOG4105MKU Transcriptional regulator DJ572_17530 ENOG4105CN1 protease DJ572_17535 ENOG4105CRP Part of the ABC transporter FtsEX involved in DJ572_17540 ENOG4105CAK Cell division ATP-binding protein ftsE DJ572_17565 ENOG4105MS2 ribosomal subunit Interface protein DJ572_17580 ENOG4105MQ3 flagellar protein FliS DJ572_17585 ENOG4107RT6 flagellar hook-associated DJ572_17590 ENOG41083S7 flagellar protein FlaG DJ572_17595 ENOG4105I03 Flagellin DJ572_17600 ENOG41085Y9 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) DJ572_17605 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) DJ572_17610 ENOG4105MKD DJ572_17615 ENOG4105DTJ flagellar hook-associated protein DJ572_17620 ENOG4105E1Q flagellar hook-associated protein DJ572_17635 ENOG4105RU3 DJ572_17640 ENOG41081UC Inherit from COG: Competence protein DJ572_17660 ENOG4105WH1 Two component transcriptional regulator luxr family DJ572_17665 ENOG4105BZU Histidine kinase DJ572_17670 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein DJ572_17675 ENOG4108KGH TRANSCRIPTIONal DJ572_17680 ENOG4105ESV Glycosyl transferase, family 4 DJ572_17685 ENOG4107EF8 Glycosyl transferase (Group 1 DJ572_17700 ENOG4105QZI O-Antigen Polymerase DJ572_17705 ENOG4105C6Y Udp-glucose 6-dehydrogenase DJ572_17710 ENOG4107RA4 Glycosyl transferase (Group 1 DJ572_17715 ENOG4105PSV Polysaccharide Biosynthesis Protein DJ572_17720 ENOG4105D3Q Sugar transferase DJ572_17730 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DJ572_17735 ENOG4105JFG SpoIID LytB domain protein DJ572_17750 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DJ572_17770 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DJ572_17775 ENOG4105EY8 ABC transporter DJ572_17795 ENOG4107VDP teichoic acid biosynthesis DJ572_17800 ENOG41088M2 Glycosyl transferase family 2 DJ572_17850 ENOG4105DG6 mannose-6-phosphate isomerase DJ572_17865 ENOG4108NHD germination protein DJ572_17870 ENOG4105C54 Major Facilitator superfamily DJ572_17875 ENOG4108KGH TRANSCRIPTIONal DJ572_17880 ENOG4105J7I hydrolase DJ572_17885 ENOG4105K4H Nlp p60 protein DJ572_17895 ENOG4105PNM synthesis protein DJ572_17905 ENOG4105N98 Capsule biosynthesis protein capB DJ572_17915 ENOG4105ETE Transcriptional regulator (LacI family DJ572_17920 ENOG4108RVA ribokinase DJ572_17925 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) DJ572_17930 ENOG4105C2J ABC transporter DJ572_17935 ENOG4105CNN ABC, transporter DJ572_17940 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator DJ572_17955 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein DJ572_17960 ENOG4107FQX Alpha-acetolactate decarboxylase DJ572_17970 ENOG4107RSM transcriptional regulator DJ572_17985 ENOG4106UIA DJ572_18000 ENOG4107XC4 flavin reductase domain protein, FMN-binding DJ572_18010 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DJ572_18020 ENOG4105CAH Chromate DJ572_18025 ENOG4105FGV Chromate DJ572_18035 ENOG4108WS4 fmn reductase DJ572_18040 ENOG4107V2S Transcriptional regulator DJ572_18045 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) DJ572_18075 ENOG4108XI2 Domain of unknown function (DUF1963) DJ572_18080 ENOG4105C6Y Udp-glucose 6-dehydrogenase DJ572_18085 ENOG4108RB3 Capsular polysaccharide biosynthesis protein DJ572_18090 ENOG4107YJ4 chain length determinant protein DJ572_18095 ENOG4105HTX biosynthesis protein DJ572_18105 ENOG4105KBK Zinc finger, swim domain protein DJ572_18110 ENOG4105C0D helicase DJ572_18120 ENOG410667J hydrolase DJ572_18125 ENOG4105E98 transcriptional regulator DeoR family DJ572_18130 ENOG4105Z8H single-stranded DNA-binding protein DJ572_18155 ENOG4108VAC response regulator DJ572_18165 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) DJ572_18170 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) DJ572_18180 ENOG4105CGA flagellar basal-body rod protein FlgG DJ572_18190 ENOG4105DFF Rod shape-determining protein mreb DJ572_18195 ENOG4105MT0 Sporulation transcriptional regulator spoiiid DJ572_18205 ENOG4107MII Sugar-specific transcriptional regulator TrmB DJ572_18210 ENOG4105CZM Major Facilitator DJ572_18215 ENOG4108M26 parallel beta-helix repeat protein DJ572_18220 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease DJ572_18225 ENOG41080V3 Major Facilitator superfamily DJ572_18230 ENOG4105D3W isochorismatase DJ572_18235 ENOG4107P26 DJ572_18240 ENOG4105BZU Histidine kinase DJ572_18250 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase DJ572_18260 ENOG4105FRN stage II sporulation protein DJ572_18265 ENOG4107TCE N-acetyltransferase DJ572_18280 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DJ572_18285 ENOG4107TXC Transcriptional regulator DJ572_18290 ENOG4106BRK DJ572_18295 ENOG4108RYK Nad-dependent epimerase dehydratase DJ572_18300 ENOG4108Z40 Transcriptional regulator DJ572_18305 ENOG4105CQM Urea amidohydrolase subunit alpha DJ572_18310 ENOG4105KI2 Urea amidohydrolase subunit beta DJ572_18315 ENOG4108YZ9 Urea amidohydrolase subunit gamma DJ572_18360 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DJ572_18370 ENOG4108TF4 von Willebrand factor, type A DJ572_18385 ENOG4105JFG SpoIID LytB domain protein DJ572_18390 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) DJ572_18400 ENOG4106778 Protein of unknown function (DUF1146) DJ572_18410 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) DJ572_18415 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) DJ572_18420 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) DJ572_18425 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) DJ572_18445 ENOG4107RB6 it plays a direct role in the translocation of protons across the membrane (By similarity) DJ572_18455 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) DJ572_18460 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) DJ572_18465 ENOG4108UIC UPF0340 protein DJ572_18470 ENOG4108YZG isomerase DJ572_18475 ENOG4107WAU Protein tyrosine phosphatase DJ572_18480 ENOG410815N Probably functions as a manganese efflux pump (By similarity) DJ572_18485 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DJ572_18495 ENOG4108ZXQ stage ii sporulation protein r DJ572_18510 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) DJ572_18515 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) DJ572_18520 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase DJ572_18530 ENOG4107TT2 Auxin Efflux Carrier DJ572_18535 ENOG4105C6K Malic enzyme DJ572_18540 ENOG4107104 thymidine kinase DJ572_18545 ENOG41082DI 50s ribosomal protein l31 DJ572_18550 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) DJ572_18555 ENOG4105CBT Fructose-1,6-bisphosphatase DJ572_18560 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) DJ572_18565 ENOG4107XMI Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway DJ572_18570 ENOG4105D2N Aldolase DJ572_18575 ENOG410812K response regulator receiver protein DJ572_18585 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) DJ572_18595 ENOG4105C1G acyl-Coa dehydrogenase DJ572_18600 ENOG4105DF6 Fe-S oxidoreductase DJ572_18610 ENOG4105E5J UV damage endonuclease DJ572_18620 ENOG4105NAE bifunctional deaminase-reductase domain protein DJ572_18625 ENOG4105BZ1 (ABC) transporter DJ572_18630 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DJ572_18645 ENOG4105R3A Nitrate reductase DJ572_18650 ENOG4108IUE nitrate reductase beta subunit DJ572_18670 ENOG4107V6Q Cyclic nucleotide-binding domain DJ572_18680 ENOG4105C75 arginyL-tRNA synthetase DJ572_18685 ENOG410684U Domain of unknown function (DUF1934) DJ572_18700 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E DJ572_18750 ENOG4107JM4 Tetratricopeptide repeat DJ572_18780 ENOG4108RDQ ABC transporter DJ572_18790 ENOG4105CYW agmatinase DJ572_18795 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) DJ572_18800 ENOG4105BZ4 penicillin-binding protein DJ572_18810 ENOG4108XFG YwhD family DJ572_18815 ENOG4108Z4T Peptidase M50 DJ572_18820 ENOG41069HH 4-oxalocrotonate tautomerase DJ572_18825 ENOG41067TZ transcriptional regulator, MarR family DJ572_18830 ENOG4105C22 threonyL-tRNA synthetase DJ572_18835 ENOG4105C57 major facilitator superfamily DJ572_18840 ENOG41062ES Transcriptional regulator DJ572_18850 ENOG4105DCI Phosphohydrolase DJ572_18860 ENOG4108VCI transcription factor, rsfa family DJ572_18865 ENOG4108RNG Permease of the drug metabolite transporter DJ572_18870 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) DJ572_18875 ENOG4105DUM transcriptional regulator, lysR family DJ572_18880 ENOG4108IJ2 phosphate acetyltransferase DJ572_18895 ENOG4105CHM Aminotransferase DJ572_18905 ENOG4108V3M Inherit from COG: acetyl-CoA carboxylase biotin carboxylase DJ572_18910 ENOG4105CHR reductase DJ572_18915 ENOG4106CHD Bacilysin biosynthesis protein bacB DJ572_18920 ENOG41061WN bacilysin biosynthesis protein DJ572_18925 ENOG4105FCW Major Facilitator superfamily DJ572_18940 ENOG4105C26 Dehydrogenase DJ572_18945 ENOG4105D82 Glutamate dehydrogenase DJ572_18955 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase DJ572_18960 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase DJ572_18965 ENOG4105C1B dTDP-glucose 4-6-dehydratase DJ572_18970 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) DJ572_18975 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG DJ572_18980 ENOG4107TY6 Acylneuraminate cytidylyltransferase DJ572_18990 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD DJ572_18995 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase DJ572_19035 ENOG4105C26 Dehydrogenase DJ572_19040 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) DJ572_19045 ENOG4108RJ9 Glycosyl transferase, family 2 DJ572_19050 ENOG4105DWF phosphomethylpyrimidine kinase DJ572_19065 ENOG4105C5Y PTS System DJ572_19070 ENOG4108QTI )-transporter DJ572_19085 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin DJ572_19090 ENOG4105DEN Luciferase family DJ572_19095 ENOG4108DBC nitroreductase DJ572_19110 ENOG41060D1 Quinol oxidase DJ572_19115 ENOG4105CCU oxidase (Subunit III) DJ572_19120 ENOG4105BZ9 Cytochrome C oxidase, subunit I DJ572_19125 ENOG4105E2S oxidase) subunit II DJ572_19130 ENOG4107BMA Transglycosylase associated protein DJ572_19140 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) DJ572_19145 ENOG4105WH5 Teichoic acid glycosylation protein DJ572_19170 ENOG4107ZXU DSBA oxidoreductase DJ572_19175 ENOG4105DBE peroxidase DJ572_19180 ENOG410650H (LipO)protein DJ572_19185 ENOG4107SJW iron permease, FTR1 DJ572_19190 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) DJ572_19200 ENOG4105CMU LysR family (Transcriptional regulator DJ572_19205 ENOG4105VAW lrga family DJ572_19210 ENOG41067MG lrgb family DJ572_19215 ENOG4105D8G Major Facilitator superfamily DJ572_19225 ENOG4105DR4 Methyltransferase DJ572_19235 ENOG4105CK1 PTS System DJ572_19240 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin DJ572_19255 ENOG4105X1N Glycosyl transferase family 8 DJ572_19265 ENOG4105GVJ transcriptional regulator DJ572_19270 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) DJ572_19275 ENOG4105IIU Aminopeptidase DJ572_19300 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase DJ572_19315 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) DJ572_19320 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DJ572_19330 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD DJ572_19335 ENOG4108VHC Short-chain dehydrogenase reductase Sdr DJ572_19340 ENOG4105CM2 brancheD-chain amino acid aminotransferase DJ572_19345 ENOG4105F8D glycoside hydrolase family 4 DJ572_19350 ENOG4105VCP PTS System DJ572_19355 ENOG4105CK1 PTS System DJ572_19360 ENOG4105VZJ PTS System DJ572_19365 ENOG4105EMD TRANSCRIPTIONal DJ572_19375 ENOG4108VX5 3-methyladenine DNA glycosylase DJ572_19380 ENOG4105CH6 catalase DJ572_19395 ENOG4105DA5 (ABC) transporter DJ572_19400 ENOG41069JR DJ572_19420 ENOG4105ETS cytosine purines uracil thiamine allantoin DJ572_19425 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) DJ572_19430 ENOG4108JJ8 (ABC) transporter DJ572_19435 ENOG4108JJ9 ABC, transporter DJ572_19440 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DJ572_19445 ENOG4105C4M (Ubiquinol oxidase) subunit I DJ572_19450 ENOG4105D2K citrate carrier protein DJ572_19465 ENOG4107BJW polysaccharide deacetylase DJ572_19485 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) DJ572_19495 ENOG4105CMR udp-glucose 4-epimerase DJ572_19500 ENOG4105KIS phospholipid-binding protein DJ572_19505 ENOG4108WAV Transcriptional regulator DJ572_19515 ENOG4105BZU Histidine kinase DJ572_19520 ENOG4105WH1 Two component transcriptional regulator luxr family DJ572_19525 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) DJ572_19550 ENOG4105DTD Dehydrogenase DJ572_19555 ENOG4108IIH CoA-transferase subunit B DJ572_19560 ENOG4105D6N CoA-transferase, subunit a DJ572_19565 ENOG4105CY2 Citrate transporter DJ572_19570 ENOG4105DHI Methyltransferase DJ572_19590 ENOG4105CH6 catalase DJ572_19595 ENOG4105D4T Citrate transporter DJ572_19600 ENOG4108RZ2 Glycoside hydrolase family 16 DJ572_19605 ENOG4105CID antiterminator DJ572_19615 ENOG4105DEU major facilitator superfamily DJ572_19620 ENOG4105C1J atp-dependent rna helicase DJ572_19625 ENOG4107TDE lipolytic protein G-D-S-L family DJ572_19660 ENOG4107YZX Universal stress protein DJ572_19665 ENOG4105CS2 ec 3.2.1.21 DJ572_19670 ENOG4105C5Y PTS System DJ572_19685 ENOG4107EV6 Inherit from COG: YD repeat protein DJ572_19700 ENOG4106Z5D Glycoside Hydrolase Family 43 DJ572_19715 ENOG4105C84 Histidine ammonia-lyase DJ572_19720 ENOG4105CGP Urocanate hydratase DJ572_19725 ENOG4105CI2 imidazolone-5-propionate hydrolase DJ572_19730 ENOG4107W25 arginase agmatinase formiminoglutamase DJ572_19740 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) DJ572_19745 ENOG4105D9N nucleoside DJ572_19755 ENOG4107RHR regulatoR DJ572_19760 ENOG4108TM9 integral membrane protein DJ572_19765 ENOG4105ENY Ethanolamine utilization protein eutH DJ572_19770 ENOG4108PGP mmge prpd family protein DJ572_19775 ENOG4105CH2 amidohydrolase DJ572_19785 ENOG4108HW4 amino acid AbC transporter DJ572_19790 ENOG4105EAB amino acid AbC transporter DJ572_19795 ENOG4108XSB acetyltransferase, (GNAT) family DJ572_19800 ENOG4105CPU Monooxygenase DJ572_19810 ENOG4107QHE Choloylglycine hydrolase DJ572_19815 ENOG410667J hydrolase DJ572_19845 ENOG4108V5C ABC transporter DJ572_19875 ENOG4105D2N Aldolase DJ572_19880 ENOG4107TRN Xylose isomerase domain protein TIM barrel DJ572_19885 ENOG4105F0H myo-inositol catabolism protein DJ572_19890 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) DJ572_19900 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) DJ572_19905 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) DJ572_19910 ENOG4105D7K pfkb domain protein DJ572_19920 ENOG4105C26 Dehydrogenase DJ572_19930 ENOG4105CPC Aldo Keto reductase DJ572_19945 ENOG4107QNK )-transporter DJ572_19950 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) DJ572_19960 ENOG41061TZ Short-chain dehydrogenase reductase Sdr DJ572_19965 ENOG4105ST3 Transcriptional regulator DJ572_19970 ENOG4105C26 Dehydrogenase DJ572_19975 ENOG4108YM7 Gcn5-related n-acetyltransferase DJ572_19980 ENOG4105N1N Cupin superfamily protein DJ572_19985 ENOG4107Y1Y Methyltransferase DJ572_20000 ENOG4105CAQ asparagine synthetase DJ572_20005 ENOG4105F22 Major Facilitator Superfamily DJ572_20010 ENOG4108ITS PQQ enzyme repeat DJ572_20020 ENOG41085PJ rdd domain containing protein DJ572_20035 ENOG4105J7D transcriptional regulator DJ572_20040 ENOG4107JEE Short-chain dehydrogenase reductase Sdr DJ572_20045 ENOG41061AU MarR family Transcriptional regulator DJ572_20055 ENOG41067MG lrgb family DJ572_20065 ENOG4105BZW Glycerate kinase DJ572_20070 ENOG4105G3Z GntR family transcriptional regulator DJ572_20075 ENOG4105CMG Carbohydrate kinase DJ572_20080 ENOG4105C6Z Gluconate DJ572_20085 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) DJ572_20090 ENOG4105D3R alkyl hydroperoxide reductase DJ572_20095 ENOG4108JU3 Alkyl hydroperoxide reductase DJ572_20105 ENOG4105CS2 ec 3.2.1.21 DJ572_20115 ENOG4105C5Y PTS System DJ572_20120 ENOG4108S3Y transcriptional regulator DJ572_20130 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 DJ572_20165 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) DJ572_20180 ENOG4105E2A Dehydrogenase DJ572_20200 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) DJ572_20205 ENOG4105WQG acetyltransferase DJ572_20210 ENOG410780I phosphoprotein phosphatase activity DJ572_20220 ENOG41066UZ arginase EC 3.5.3.1 DJ572_20225 ENOG4108IQI permease DJ572_20230 ENOG4105C8Y Acetylornithine aminotransferase DJ572_20235 ENOG4108JUB Transcriptional regulator DJ572_20240 ENOG4105BZU Histidine kinase DJ572_20260 ENOG4105C0H protease DJ572_20265 ENOG4105Q2H domain protein DJ572_20280 ENOG4105BZU Histidine kinase DJ572_20285 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ572_20310 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis DJ572_20315 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase DJ572_20320 ENOG4105CDU Replicative dna helicase DJ572_20340 ENOG4105DJ2 Major Facilitator Superfamily DJ572_20345 ENOG4105EDW glycosyl transferase, family 39 DJ572_20350 ENOG4105K9Q Binds to the 23S rRNA (By similarity) DJ572_20355 ENOG4105BZR domain protein DJ572_20360 ENOG4108XMW Membrane DJ572_20375 ENOG4105KVH Transcriptional regulator DJ572_20380 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase DJ572_20400 ENOG41090E6 transcriptional regulator MERR family DJ572_20410 ENOG4108VSZ Inherit from COG: ketosteroid isomerase-like protein DJ572_20415 ENOG4105DDN Pentapeptide repeat-containing protein DJ572_20420 ENOG4105D94 Major Facilitator Superfamily DJ572_20425 ENOG4107RSM transcriptional regulator DJ572_20430 ENOG41082BV acetyltransferase DJ572_20435 ENOG41081I9 integral membrane protein DJ572_20450 ENOG4108U05 Transcriptional regulator DJ572_20455 ENOG41082BV acetyltransferase DJ572_20465 ENOG4108U7W acetyltransferase DJ572_20470 ENOG4105UNS Pfam:DUF419 DJ572_20475 ENOG4105NAE bifunctional deaminase-reductase domain protein DJ572_20485 ENOG4108J8C transporter major facilitator family protein DJ572_20495 ENOG4105C7Z Conserved Protein DJ572_20500 ENOG4108UXE Protein tyrosine phosphatase DJ572_20505 ENOG4105D6J arsenicaL-resistance protein DJ572_20510 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase DJ572_20515 ENOG41085FC arsR family transcriptional regulator DJ572_20540 ENOG4105K4H Nlp p60 protein DJ572_20550 ENOG4105P1M Domain of unknown function (DUF1874) DJ572_20585 ENOG4106128 DNA-binding helix-turn-helix protein DJ572_20590 ENOG4106BHR ftsk SpoIIIE family protein DJ572_20595 ENOG4108RYM conjugative transposon protein DJ572_20615 ENOG4108IMY Transcriptional regulator DJ572_20620 ENOG41068WC Domain of unknown function (DUF955) DJ572_20640 ENOG4105C7Z Conserved Protein DJ572_20645 ENOG4105C7Z Conserved Protein DJ572_20650 ENOG4107FCW Abortive infection protein DJ572_20660 ENOG4108UW5 maltose o-acetyltransferase DJ572_20665 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase DJ572_20675 ENOG4105CGK Exodeoxyribonuclease III DJ572_20680 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) DJ572_20685 ENOG4108UUM single-stranded DNA-binding protein DJ572_20690 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) DJ572_20695 ENOG4105C3G gtp-binding protein DJ572_20700 ENOG4108J2R molybdopterin oxidoreductase DJ572_20705 ENOG4105VDK protein, conserved in bacteria DJ572_20715 ENOG4108ZDA Sporulation protein YyaC DJ572_20720 ENOG4105FA0 parb-like partition protein DJ572_20725 ENOG4107QJE Chromosome Partitioning Protein DJ572_20740 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) DJ572_20745 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) DJ572_20750 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) DJ572_20765 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) DJ572_20775 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) DJ572_20780 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) DJ572_20785 ENOG410848D S4 domain protein YaaA DJ572_20800 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DJ572_20805 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DJ572_20840 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) DJ572_20850 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) DJ572_20855 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) DJ572_20865 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) DJ572_20875 ENOG4105ZMH deoxynucleoside kinase DJ572_20885 ENOG4105VRS hydrolase family 18 DJ572_20890 ENOG4105GTG Isochorismatase DJ572_20895 ENOG4108Z6B deaminase DJ572_20905 ENOG4105C6E dna polymerase iii DJ572_20910 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) DJ572_20915 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) DJ572_20925 ENOG41067KS pro-sigma K processing DJ572_20965 ENOG4105CDW Resistance protein DJ572_20970 ENOG4105CXN decarboxylase DJ572_20975 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) DJ572_20980 ENOG4105X0R protein from nitrogen regulatory protein P-II DJ572_20985 ENOG4105XVJ Protein of unknown function (DUF327) DJ572_20990 ENOG4105FA2 dna polymerase iii DJ572_20995 ENOG4105MA4 psp1 domain protein DJ572_21000 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) DJ572_21005 ENOG41060K3 Methyltransferase DJ572_21010 ENOG4105VC4 domain protein DJ572_21015 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) DJ572_21020 ENOG4105KRN Transcriptional regulator, abrb family DJ572_21025 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) DJ572_21030 ENOG4105F8V Hydrolase, tatD family DJ572_21035 ENOG41069ER domain protein DJ572_21045 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) DJ572_21050 ENOG4105XFA sporulation peptidase YabG DJ572_21055 ENOG4105W42 Veg protein DJ572_21060 ENOG4105XEW small acid-soluble spore protein DJ572_21065 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) DJ572_21070 ENOG4105DFT pur operon repressor DJ572_21075 ENOG4105KME endoribonuclease L-psp DJ572_21080 ENOG4105K4W Could be involved in septation (By similarity) DJ572_21085 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) DJ572_21090 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DJ572_21095 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) DJ572_21100 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) DJ572_21110 ENOG4108JA2 transcriptioN-repair coupling factor DJ572_21115 ENOG4108M14 stage v sporulation protein t DJ572_21125 ENOG4108IY2 MazG family DJ572_21130 ENOG41082I2 s4 domain protein DJ572_21135 ENOG4105VYY sporulation protein yabp DJ572_21150 ENOG41060GV RNA binding s1 domain protein DJ572_21180 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) DJ572_21185 ENOG4108UGV hypoxanthine phosphoribosyltransferase DJ572_21190 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) DJ572_21200 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) DJ572_21205 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase DJ572_21210 ENOG4105C6T cysteine synthase DJ572_21215 ENOG4105CRQ synthase (Component I) DJ572_21220 ENOG4105DDQ anthranilate synthase DJ572_21225 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 DJ572_21230 ENOG4105EEI dihydropteroate synthase DJ572_21235 ENOG4105KRF dihydroneopterin aldolase DJ572_21240 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase DJ572_21250 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DJ572_21255 ENOG4105CRK lysyL-tRNA synthetase DJ572_21410 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) DJ572_21415 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)