locus-tag	class	description
CAH07_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CAH07_00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CAH07_00015	COG0594	ribonuclease P activity
CAH07_00020	COG0706	membrane insertase activity
CAH07_00025	COG1847	R3H domain protein
CAH07_00030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CAH07_00035	COG0445	tRNA wobble uridine modification
CAH07_00040	COG0357	Ribosomal RNA small subunit methyltransferase G
CAH07_00045	COG1475	DNA binding
CAH07_00055	COG1192	Involved in chromosome partitioning
CAH07_00060	COG1475	DNA binding
CAH07_00070	COG3949	Membrane
CAH07_00075	COG4481	Protein conserved in bacteria
CAH07_00080	COG0243	molybdopterin cofactor binding
CAH07_00085	COG0012	GTP binding
CAH07_00090	COG0360	Binds together with S18 to 16S ribosomal RNA
CAH07_00095	COG0629	single-stranded DNA binding
CAH07_00100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CAH07_00105	COG0708	Exodeoxyribonuclease III
CAH07_00110	COG1609	Transcriptional regulator
CAH07_00115	COG0346	lactoylglutathione lyase activity
CAH07_00120	COG0110	maltose O-acetyltransferase activity
CAH07_00125	COG2814	Major facilitator Superfamily
CAH07_00125	COG0477	Major facilitator Superfamily
CAH07_00130	COG1266	CAAX protease self-immunity
CAH07_00135	COG1331	Highly conserved protein containing a thioredoxin domain
CAH07_00140	COG2814	Major facilitator Superfamily
CAH07_00150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CAH07_00155	COG2315	Protein conserved in bacteria
CAH07_00160	COG0456	acetyltransferase
CAH07_00165	COG2364	Membrane
CAH07_00170	COG2153	protein acetylation
CAH07_00175	COG1846	Transcriptional regulator
CAH07_00180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAH07_00190	COG2153	protein acetylation
CAH07_00195	COG0583	DNA-binding transcription factor activity
CAH07_00200	COG2814	Major facilitator Superfamily
CAH07_00205	COG1357	PFAM Pentapeptide repeats (8 copies)
CAH07_00210	COG4319	ketosteroid isomerase
CAH07_00220	COG4978	Transcriptional regulator
CAH07_00220	COG0789	Transcriptional regulator
CAH07_00225	COG2271	Major facilitator Superfamily
CAH07_00235	COG1227	inorganic diphosphatase activity
CAH07_00240	COG1733	regulation of RNA biosynthetic process
CAH07_00245	COG5577	PFAM Coat F domain
CAH07_00255	COG4241	membrane
CAH07_00260	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CAH07_00265	COG0359	binds to the 23S rRNA
CAH07_00270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CAH07_00275	COG2807	transmembrane transport
CAH07_00280	COG3093	addiction module antidote protein HigA
CAH07_00295	COG0305	Participates in initiation and elongation during chromosome replication
CAH07_00300	COG0346	lactoylglutathione lyase activity
CAH07_00330	COG0745	RESPONSE REGULATOR receiver
CAH07_00335	COG5002	protein histidine kinase activity
CAH07_00340	COG4863	YycH protein
CAH07_00345	COG4853	Protein conserved in bacteria
CAH07_00350	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CAH07_00355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAH07_00375	COG5002	protein histidine kinase activity
CAH07_00380	COG3829	transcription factor binding
CAH07_00385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CAH07_00390	COG0833	amino acid
CAH07_00395	COG0010	Belongs to the arginase family
CAH07_00405	COG0457	Tetratricopeptide repeat
CAH07_00410	COG0456	acetyltransferase
CAH07_00415	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CAH07_00435	COG1063	alcohol dehydrogenase
CAH07_00450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CAH07_00485	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CAH07_00495	COG2188	Transcriptional regulator
CAH07_00510	COG2723	6-phospho-beta-galactosidase activity
CAH07_00520	COG3634	alkyl hydroperoxide reductase activity
CAH07_00525	COG0450	alkyl hydroperoxide reductase
CAH07_00530	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CAH07_00535	COG2610	gluconate transmembrane transporter activity
CAH07_00540	COG1070	Carbohydrate kinase
CAH07_00545	COG1802	Transcriptional regulator
CAH07_00550	COG1929	Belongs to the glycerate kinase type-1 family
CAH07_00555	COG5039	Polysaccharide pyruvyl transferase
CAH07_00560	COG1346	cytolysis
CAH07_00565	COG1380	Effector of murein hydrolase LrgA
CAH07_00570	COG1846	Transcriptional regulator
CAH07_00575	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_00580	COG1309	transcriptional regulator
CAH07_00585	COG1917	Cupin 2, conserved barrel domain protein
CAH07_00590	COG2311	Membrane
CAH07_00605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAH07_00610	COG2814	Major facilitator Superfamily
CAH07_00615	COG0367	asparagine synthase
CAH07_00630	COG2226	methyltransferase
CAH07_00635	COG2850	peptidyl-arginine hydroxylation
CAH07_00640	COG0456	acetyltransferase
CAH07_00645	COG1012	belongs to the aldehyde dehydrogenase family
CAH07_00650	COG1309	transcriptional regulator
CAH07_00655	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_00665	COG0326	Molecular chaperone. Has ATPase activity
CAH07_00670	COG2814	Major facilitator Superfamily
CAH07_00685	COG0667	Aldo Keto reductase
CAH07_00690	COG1349	DNA-binding transcription factor activity
CAH07_00695	COG1012	belongs to the aldehyde dehydrogenase family
CAH07_00705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAH07_00710	COG3962	Belongs to the TPP enzyme family
CAH07_00715	COG1082	Xylose isomerase domain protein TIM barrel
CAH07_00720	COG2814	Major facilitator Superfamily
CAH07_00725	COG0673	inositol 2-dehydrogenase activity
CAH07_00730	COG1082	Xylose isomerase domain protein TIM barrel
CAH07_00735	COG1082	Xylose isomerase domain protein TIM barrel
CAH07_00740	COG0191	fructose-bisphosphate aldolase activity
CAH07_00745	COG0745	RESPONSE REGULATOR receiver
CAH07_00750	COG2205	protein histidine kinase activity
CAH07_00755	COG1136	(ABC) transporter
CAH07_00760	COG0577	efflux transmembrane transporter activity
CAH07_00765	COG5294	Protein conserved in bacteria
CAH07_00770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CAH07_00800	COG0561	phosphatase activity
CAH07_00805	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CAH07_00820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAH07_00825	COG0765	amino acid transport
CAH07_00830	COG1126	abc transporter atp-binding protein
CAH07_00840	COG2079	MmgE PrpD family protein
CAH07_00845	COG3192	ethanolamine utilization protein
CAH07_00855	COG2390	Transcriptional regulator
CAH07_00860	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CAH07_00865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CAH07_00870	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CAH07_00875	COG0833	amino acid
CAH07_00880	COG0010	Belongs to the arginase family
CAH07_00885	COG1228	amidohydrolase
CAH07_00890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CAH07_00895	COG2986	histidine ammonia-lyase
CAH07_00910	COG3507	Belongs to the glycosyl hydrolase 43 family
CAH07_00915	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CAH07_00920	COG0494	nUDIX hydrolase
CAH07_00940	COG5444	nuclease activity
CAH07_00965	COG1263	PTS System
CAH07_00965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAH07_00965	COG2190	(PTS) system
CAH07_00970	COG2723	6-phospho-beta-galactosidase activity
CAH07_00975	COG0589	response to stress
CAH07_00995	COG0789	Transcriptional regulator
CAH07_01005	COG0697	spore germination
CAH07_01010	COG3209	COG3209 Rhs family protein
CAH07_01060	COG3401	FG-GAP repeat protein
CAH07_01060	COG2755	lipolytic protein G-D-S-L family
CAH07_01065	COG0513	Belongs to the DEAD box helicase family
CAH07_01070	COG2270	Major facilitator Superfamily
CAH07_01080	COG3711	transcriptional antiterminator
CAH07_01085	COG2273	Hydrolase Family 16
CAH07_01090	COG2851	Citrate transporter
CAH07_01095	COG0753	catalase activity
CAH07_01095	COG0693	protein deglycase activity
CAH07_01110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CAH07_01115	COG0500	methyltransferase
CAH07_01120	COG2610	gluconate transmembrane transporter activity
CAH07_01125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CAH07_01130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAH07_01135	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_01140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CAH07_01145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CAH07_01150	COG4894	glucomannan catabolic process
CAH07_01160	COG2195	Cleaves the N-terminal amino acid of tripeptides
CAH07_01165	COG2197	response regulator
CAH07_01170	COG4585	Histidine kinase
CAH07_01180	COG0583	DNA-binding transcription factor activity
CAH07_01185	COG1881	PFAM PEBP family protein
CAH07_01190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CAH07_01200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CAH07_01205	COG1012	belongs to the aldehyde dehydrogenase family
CAH07_01210	COG2508	Transcriptional regulator
CAH07_01215	COG3842	ATPase activity
CAH07_01220	COG0726	polysaccharide deacetylase
CAH07_01230	COG0501	Belongs to the peptidase M48B family
CAH07_01235	COG3493	citrate carrier protein
CAH07_01240	COG1271	oxidase subunit
CAH07_01245	COG1294	oxidase, subunit
CAH07_01250	COG4988	ABC transporter
CAH07_01255	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CAH07_01260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CAH07_01265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CAH07_01270	COG1595	DNA-templated transcription, initiation
CAH07_01290	COG1131	(ABC) transporter
CAH07_01295	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CAH07_01300	COG2814	Major facilitator Superfamily
CAH07_01305	COG0753	catalase activity
CAH07_01310	COG2094	Belongs to the DNA glycosylase MPG family
CAH07_01320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAH07_01320	COG3711	transcriptional antiterminator
CAH07_01325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CAH07_01330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CAH07_01335	COG1447	Phosphotransferase system cellobiose-specific component IIA
CAH07_01340	COG1486	melibiose metabolic process
CAH07_01345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CAH07_01350	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CAH07_01355	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CAH07_01360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAH07_01365	COG1696	Membrane protein involved in D-alanine export
CAH07_01370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_01385	COG1575	Belongs to the MenA family. Type 1 subfamily
CAH07_01390	COG2357	RelA SpoT domain protein
CAH07_01395	COG2814	Major facilitator Superfamily
CAH07_01410	COG2234	aminopeptidase activity
CAH07_01415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CAH07_01420	COG1846	Transcriptional regulator
CAH07_01425	COG5522	Integral membrane protein (intg_mem_TP0381)
CAH07_01430	COG1442	glycosyl transferase family 8
CAH07_01435	COG3711	transcriptional antiterminator
CAH07_01440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAH07_01440	COG1263	PTS System
CAH07_01445	COG1404	Belongs to the peptidase S8 family
CAH07_01450	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CAH07_01455	COG0346	lactoylglutathione lyase activity
CAH07_01460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CAH07_01465	COG4895	conserved protein (DUF2196)
CAH07_01470	COG2814	Major facilitator Superfamily
CAH07_01475	COG1346	cytolysis
CAH07_01480	COG1380	Effector of murein hydrolase LrgA
CAH07_01485	COG0583	DNA-binding transcription factor activity
CAH07_01490	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CAH07_01495	COG0352	thiamine-phosphate diphosphorylase activity
CAH07_01500	COG0672	)-iron permease
CAH07_01505	COG2822	iron ion transport
CAH07_01510	COG2837	iron assimilation
CAH07_01515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CAH07_01520	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAH07_01525	COG3162	membrane
CAH07_01535	COG1309	transcriptional regulator
CAH07_01540	COG2246	polysaccharide biosynthetic process
CAH07_01545	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CAH07_01550	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CAH07_01555	COG2261	transglycosylase associated protein
CAH07_01560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CAH07_01565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAH07_01570	COG1845	cytochrome c oxidase, subunit III
CAH07_01575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CAH07_01585	COG0772	Belongs to the SEDS family
CAH07_01590	COG0778	Nitroreductase
CAH07_01595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAH07_01600	COG1404	Belongs to the peptidase S8 family
CAH07_01610	COG3711	transcriptional antiterminator
CAH07_01615	COG2116	formate transmembrane transporter activity
CAH07_01620	COG1263	PTS System
CAH07_01620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAH07_01625	COG1621	beta-fructofuranosidase activity
CAH07_01635	COG0351	phosphomethylpyrimidine kinase
CAH07_01640	COG1695	Transcriptional regulator
CAH07_01655	COG1216	Glycosyl transferase, family 2
CAH07_01660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CAH07_01665	COG1012	belongs to the aldehyde dehydrogenase family
CAH07_01675	COG2233	PERMEase
CAH07_01680	COG2363	Small membrane protein
CAH07_01695	COG0463	Glycosyl transferase, family 2
CAH07_01700	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CAH07_01705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CAH07_01710	COG0456	acetyltransferase
CAH07_01715	COG2089	acid synthase
CAH07_01720	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CAH07_01725	COG3980	spore coat polysaccharide biosynthesis protein
CAH07_01730	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CAH07_01735	COG1088	dTDP-glucose 4,6-dehydratase activity
CAH07_01740	COG1091	dTDP-4-dehydrorhamnose reductase activity
CAH07_01745	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CAH07_01755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CAH07_01760	COG1012	belongs to the aldehyde dehydrogenase family
CAH07_01765	COG4187	Peptidase family M20/M25/M40
CAH07_01770	COG0833	amino acid
CAH07_01775	COG2814	Major facilitator Superfamily
CAH07_01780	COG0077	Prephenate dehydratase
CAH07_01785	COG1917	Cupin 2, conserved barrel domain protein
CAH07_01790	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_01795	COG0151	Belongs to the GarS family
CAH07_01800	COG2814	Major facilitator Superfamily
CAH07_01805	COG0436	Aminotransferase
CAH07_01810	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_01820	COG0280	phosphate acetyltransferase
CAH07_01825	COG0583	DNA-binding transcription factor activity
CAH07_01830	COG0095	Lipoate-protein ligase
CAH07_01835	COG0697	spore germination
CAH07_01845	COG4844	belongs to the
CAH07_01850	COG1078	dGTPase activity
CAH07_01855	COG3465	dGTPase activity
CAH07_01860	COG1959	2 iron, 2 sulfur cluster binding
CAH07_01865	COG0477	Major facilitator Superfamily
CAH07_01870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CAH07_01875	COG1846	Transcriptional regulator
CAH07_01880	COG1942	4-Oxalocrotonate Tautomerase
CAH07_01885	COG1994	Peptidase M50
CAH07_01900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAH07_01905	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CAH07_01910	COG0010	Belongs to the arginase family
CAH07_01920	COG1131	(ABC) transporter
CAH07_01950	COG0457	Tetratricopeptide repeat
CAH07_01960	COG3391	amine dehydrogenase activity
CAH07_01965	COG3391	amine dehydrogenase activity
CAH07_01975	COG0612	Peptidase, M16
CAH07_01980	COG0612	Peptidase, M16
CAH07_01985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CAH07_01990	COG1131	(ABC) transporter
CAH07_02000	COG0535	radical SAM domain protein
CAH07_02015	COG4506	Protein conserved in bacteria
CAH07_02020	COG0018	arginyl-trna synthetase
CAH07_02025	COG2223	nitrite transmembrane transporter activity
CAH07_02030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAH07_02040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAH07_02045	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CAH07_02050	COG1140	nitrate reductase beta subunit
CAH07_02055	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CAH07_02060	COG2181	nitrate reductase activity
CAH07_02065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAH07_02070	COG1132	(ABC) transporter
CAH07_02075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CAH07_02085	COG4294	response to UV
CAH07_02090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAH07_02095	COG0247	lactate metabolic process
CAH07_02095	COG2181	nitrate reductase activity
CAH07_02100	COG1960	acyl-CoA dehydrogenase activity
CAH07_02105	COG3343	RNA polymerase activity
CAH07_02110	COG0504	CTP synthase activity
CAH07_02115	COG4821	SIS domain
CAH07_02120	COG2204	response regulator
CAH07_02125	COG0191	fructose-bisphosphate aldolase activity
CAH07_02130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CAH07_02135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CAH07_02140	COG1494	fructose-1,6-bisphosphatase
CAH07_02145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CAH07_02150	COG0254	rRNA binding
CAH07_02155	COG1435	thymidine kinase activity
CAH07_02160	COG0281	malic enzyme
CAH07_02165	COG0679	Auxin Efflux Carrier
CAH07_02170	COG0789	Transcriptional regulator
CAH07_02175	COG0346	lactoylglutathione lyase activity
CAH07_02180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CAH07_02185	COG2890	protein-(glutamine-N5) methyltransferase activity
CAH07_02205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CAH07_02210	COG0009	L-threonylcarbamoyladenylate synthase
CAH07_02215	COG1971	Probably functions as a manganese efflux pump
CAH07_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CAH07_02225	COG0698	ribose 5-phosphate isomerase
CAH07_02230	COG4475	Protein of unknown function (DUF436)
CAH07_02235	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CAH07_02240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CAH07_02250	COG0356	it plays a direct role in the translocation of protons across the membrane
CAH07_02255	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CAH07_02260	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CAH07_02265	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CAH07_02270	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CAH07_02275	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CAH07_02280	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CAH07_02285	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CAH07_02295	COG4836	Membrane
CAH07_02305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CAH07_02310	COG2385	sporulation resulting in formation of a cellular spore
CAH07_02315	COG2304	oxidoreductase activity
CAH07_02325	COG2304	oxidoreductase activity
CAH07_02335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CAH07_02340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CAH07_02350	COG0457	Tetratricopeptide repeat
CAH07_02355	COG1994	Peptidase M50
CAH07_02360	COG3237	CsbD-like
CAH07_02375	COG0831	urea catabolic process
CAH07_02380	COG0832	Belongs to the urease beta subunit family
CAH07_02385	COG0804	urea catabolic process
CAH07_02390	COG1959	2 iron, 2 sulfur cluster binding
CAH07_02395	COG2910	NAD(P)H-binding
CAH07_02405	COG0789	Transcriptional regulator
CAH07_02410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAH07_02425	COG1247	-acetyltransferase
CAH07_02430	COG0739	heme binding
CAH07_02440	COG0671	phosphoesterase, PA-phosphatase related
CAH07_02445	COG0347	Belongs to the P(II) protein family
CAH07_02450	COG0004	ammonium transporteR
CAH07_02460	COG1335	isochorismatase
CAH07_02465	COG0477	Major facilitator Superfamily
CAH07_02470	COG1953	Uracil, thiamine, allantoin
CAH07_02475	COG3420	alginic acid biosynthetic process
CAH07_02480	COG2814	Major facilitator Superfamily
CAH07_02485	COG1846	Transcriptional regulator
CAH07_02495	COG1609	Transcriptional regulator
CAH07_02500	COG1077	Cell shape determining protein MreB Mrl
CAH07_02505	COG4786	Flagellar basal body rod
CAH07_02510	COG4786	Flagellar basal body rod
CAH07_02515	COG0457	Tetratricopeptide repeat
CAH07_02520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CAH07_02525	COG1970	mechanosensitive ion channel activity
CAH07_02530	COG2972	Histidine kinase
CAH07_02530	COG0745	RESPONSE REGULATOR receiver
CAH07_02535	COG3764	Sortase (surface protein transpeptidase)
CAH07_02550	COG0629	single-stranded DNA binding
CAH07_02555	COG1349	DNA-binding transcription factor activity
CAH07_02560	COG0561	phosphatase activity
CAH07_02570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CAH07_02575	COG4715	Zinc finger, swim domain protein
CAH07_02585	COG3944	biosynthesis protein
CAH07_02590	COG0489	protein tyrosine kinase activity
CAH07_02595	COG4464	protein tyrosine phosphatase activity
CAH07_02600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CAH07_02605	COG3878	Protein conserved in bacteria
CAH07_02625	COG5444	nuclease activity
CAH07_02640	COG0583	DNA-binding transcription factor activity
CAH07_02645	COG0655	NAD(P)H dehydrogenase (quinone) activity
CAH07_02655	COG2059	Chromate
CAH07_02660	COG2059	Chromate
CAH07_02665	COG1522	sequence-specific DNA binding
CAH07_02670	COG0405	Gamma-glutamyltransferase
CAH07_02680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAH07_02690	COG5337	Spore coat protein CotH
CAH07_02705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CAH07_02710	COG0583	DNA-binding transcription factor activity
CAH07_02715	COG0028	Belongs to the TPP enzyme family
CAH07_02720	COG3527	Alpha-acetolactate decarboxylase
CAH07_02725	COG2249	NAD(P)H dehydrogenase (quinone) activity
CAH07_02735	COG3103	Sh3 type 3 domain protein
CAH07_02740	COG1879	ABC-type sugar transport system periplasmic component
CAH07_02745	COG1172	Belongs to the binding-protein-dependent transport system permease family
CAH07_02750	COG1129	ABC transporter
CAH07_02755	COG1869	D-ribose catabolic process
CAH07_02760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAH07_02765	COG1609	Transcriptional regulator
CAH07_02775	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CAH07_02785	COG2843	Capsule synthesis protein
CAH07_02795	COG0791	NLP P60 protein
CAH07_02800	COG0561	phosphatase activity
CAH07_02805	COG1316	TRANSCRIPTIONal
CAH07_02810	COG2814	Major facilitator Superfamily
CAH07_02820	COG0814	amino acid
CAH07_02825	COG0697	spore germination
CAH07_02830	COG1482	cell wall glycoprotein biosynthetic process
CAH07_02835	COG4193	domain, Protein
CAH07_02880	COG0463	Glycosyl transferase, family 2
CAH07_02900	COG1682	transport, permease protein
CAH07_02905	COG1134	teichoic acid transport
CAH07_02910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CAH07_02930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CAH07_02935	COG1316	TRANSCRIPTIONal
CAH07_02945	COG2247	cell wall binding repeat
CAH07_02945	COG2385	sporulation resulting in formation of a cellular spore
CAH07_02950	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAH07_02950	COG2247	cell wall binding repeat
CAH07_02965	COG2244	polysaccharide biosynthetic process
CAH07_02970	COG0438	transferase activity, transferring glycosyl groups
CAH07_02970	COG0297	glycogen (starch) synthase activity
CAH07_02975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CAH07_02980	COG3307	-O-antigen
CAH07_02985	COG3206	protein involved in exopolysaccharide biosynthesis
CAH07_02990	COG1215	transferase activity, transferring glycosyl groups
CAH07_02995	COG0438	transferase activity, transferring glycosyl groups
CAH07_03000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAH07_03005	COG1316	TRANSCRIPTIONal
CAH07_03010	COG1739	Uncharacterized protein family UPF0029
CAH07_03015	COG4585	Histidine kinase
CAH07_03020	COG2197	response regulator
CAH07_03025	COG1307	EDD domain protein, DegV family
CAH07_03030	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CAH07_03040	COG1040	competence protein
CAH07_03050	COG2747	anti-sigma28 factor FlgM
CAH07_03055	COG3418	PFAM FlgN family protein
CAH07_03060	COG4786	Flagellar basal body rod
CAH07_03060	COG1256	bacterial-type flagellum assembly
CAH07_03065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAH07_03075	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CAH07_03080	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CAH07_03085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAH07_03090	COG1334	flagellar protein FlaG
CAH07_03095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CAH07_03100	COG1516	flagellar protein fliS
CAH07_03115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CAH07_03120	COG0653	protein targeting
CAH07_03125	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CAH07_03130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CAH07_03135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CAH07_03140	COG2010	Cytochrome c
CAH07_03145	COG2884	Cell division ATP-binding protein ftsE
CAH07_03150	COG2177	Part of the ABC transporter FtsEX involved in
CAH07_03155	COG0793	Belongs to the peptidase S41A family
CAH07_03155	COG3409	Peptidoglycan-binding domain 1 protein
CAH07_03165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAH07_03170	COG2814	Major facilitator Superfamily
CAH07_03175	COG1309	transcriptional regulator
CAH07_03180	COG0574	Belongs to the PEP-utilizing enzyme family
CAH07_03180	COG3848	Pyruvate phosphate dikinase
CAH07_03185	COG4897	Protein conserved in bacteria
CAH07_03195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CAH07_03200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAH07_03215	COG3595	metallopeptidase activity
CAH07_03220	COG1983	PspC domain protein
CAH07_03225	COG1950	PFAM Membrane protein of
CAH07_03230	COG2814	Major facilitator Superfamily
CAH07_03235	COG1846	Transcriptional regulator
CAH07_03245	COG2124	cytochrome p450
CAH07_03250	COG1846	Transcriptional regulator
CAH07_03255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAH07_03265	COG0363	glucosamine-6-phosphate deaminase activity
CAH07_03270	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CAH07_03275	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CAH07_03280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CAH07_03285	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CAH07_03290	COG0546	phosphoglycolate phosphatase activity
CAH07_03295	COG0110	maltose O-acetyltransferase activity
CAH07_03300	COG5297	Belongs to the glycosyl hydrolase family 6
CAH07_03305	COG4990	cell redox homeostasis
CAH07_03310	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CAH07_03315	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CAH07_03320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CAH07_03325	COG0131	Imidazoleglycerol-phosphate dehydratase
CAH07_03330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CAH07_03335	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CAH07_03340	COG0107	imidazoleglycerol-phosphate synthase activity
CAH07_03345	COG0140	phosphoribosyl-ATP diphosphatase activity
CAH07_03345	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CAH07_03370	COG1132	(ABC) transporter
CAH07_03375	COG0457	Tetratricopeptide repeat
CAH07_03380	COG0791	NLP P60 protein
CAH07_03380	COG3883	PFAM NLP P60 protein
CAH07_03385	COG0492	ferredoxin-NADP+ reductase activity
CAH07_03390	COG1051	belongs to the nudix hydrolase family
CAH07_03395	COG1660	Displays ATPase and GTPase activities
CAH07_03400	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CAH07_03405	COG1481	regulation of sporulation
CAH07_03410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAH07_03415	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CAH07_03425	COG0745	RESPONSE REGULATOR receiver
CAH07_03430	COG5002	protein histidine kinase activity
CAH07_03435	COG1136	(ABC) transporter
CAH07_03440	COG0577	efflux transmembrane transporter activity
CAH07_03445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAH07_03450	COG0288	reversible hydration of carbon dioxide
CAH07_03455	COG0659	secondary active sulfate transmembrane transporter activity
CAH07_03460	COG1694	Mazg nucleotide pyrophosphohydrolase
CAH07_03465	COG1611	Belongs to the LOG family
CAH07_03470	COG1609	Transcriptional regulator
CAH07_03480	COG2182	Extracellular solute-binding protein
CAH07_03485	COG1175	transmembrane transport
CAH07_03490	COG3833	ABC-type maltose transport systems, permease component
CAH07_03495	COG5521	maltodextrose utilization protein MalA
CAH07_03500	COG1554	hydrolase, family 65, central catalytic
CAH07_03505	COG0366	Alpha amylase catalytic
CAH07_03510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAH07_03515	COG0740	serine-type endopeptidase activity
CAH07_03525	COG3621	Patatin-like phospholipase
CAH07_03530	COG0277	FAD linked oxidase domain protein
CAH07_03540	COG2076	Multidrug Resistance protein
CAH07_03545	COG2076	Multidrug Resistance protein
CAH07_03550	COG1309	transcriptional regulator
CAH07_03555	COG0531	amino acid
CAH07_03560	COG1621	beta-fructofuranosidase activity
CAH07_03565	COG1621	beta-fructofuranosidase activity
CAH07_03570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CAH07_03575	COG1794	racemase activity, acting on amino acids and derivatives
CAH07_03585	COG3479	Phenolic acid decarboxylase
CAH07_03595	COG2272	Belongs to the type-B carboxylesterase lipase family
CAH07_03600	COG1396	sequence-specific DNA binding
CAH07_03605	COG3944	biosynthesis protein
CAH07_03610	COG0489	protein tyrosine kinase activity
CAH07_03615	COG1086	Polysaccharide biosynthesis protein
CAH07_03620	COG0438	transferase activity, transferring glycosyl groups
CAH07_03625	COG1215	transferase activity, transferring glycosyl groups
CAH07_03630	COG0438	transferase activity, transferring glycosyl groups
CAH07_03640	COG1216	Glycosyl transferase, family 2
CAH07_03645	COG5039	Polysaccharide pyruvyl transferase
CAH07_03650	COG1216	Glycosyl transferase, family 2
CAH07_03655	COG2244	polysaccharide biosynthetic process
CAH07_03660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CAH07_03665	COG0110	maltose O-acetyltransferase activity
CAH07_03670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CAH07_03675	COG5039	Polysaccharide pyruvyl transferase
CAH07_03685	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CAH07_03690	COG1620	l-lactate permease
CAH07_03695	COG2186	Transcriptional regulator
CAH07_03700	COG1609	Transcriptional regulator
CAH07_03705	COG2182	Extracellular solute-binding protein
CAH07_03710	COG1175	transmembrane transport
CAH07_03715	COG3833	ABC-type maltose transport systems, permease component
CAH07_03720	COG1874	Beta-galactosidase
CAH07_03725	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CAH07_03730	COG2208	phosphoserine phosphatase activity
CAH07_03735	COG0596	Alpha beta hydrolase
CAH07_03740	COG1131	(ABC) transporter
CAH07_03745	COG0842	Transport permease protein
CAH07_03750	COG4585	Histidine kinase
CAH07_03755	COG2197	response regulator
CAH07_03760	COG0247	lactate metabolic process
CAH07_03765	COG1139	Iron-sulfur cluster binding protein
CAH07_03770	COG1556	Lactate utilization protein
CAH07_03775	COG3858	chitin binding
CAH07_03780	COG1113	amino acid transport
CAH07_03785	COG0697	spore germination
CAH07_03790	COG0583	DNA-binding transcription factor activity
CAH07_03800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAH07_03805	COG1609	Transcriptional regulator
CAH07_03810	COG2814	Major facilitator Superfamily
CAH07_03815	COG2390	Transcriptional regulator
CAH07_03820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CAH07_03825	COG0126	phosphoglycerate kinase activity
CAH07_03830	COG0149	triose-phosphate isomerase activity
CAH07_03835	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CAH07_03840	COG0148	phosphopyruvate hydratase activity
CAH07_03845	COG0456	acetyltransferase
CAH07_03850	COG4640	response to antibiotic
CAH07_03855	COG3064	Membrane
CAH07_03865	COG2095	MarC family integral membrane protein
CAH07_03870	COG1510	regulation of RNA biosynthetic process
CAH07_03875	COG1125	glycine betaine transport
CAH07_03875	COG0517	IMP dehydrogenase activity
CAH07_03880	COG1174	glycine betaine transport
CAH07_03885	COG1732	Glycine betaine
CAH07_03890	COG1174	glycine betaine transport
CAH07_03895	COG1510	regulation of RNA biosynthetic process
CAH07_03900	COG0517	IMP dehydrogenase activity
CAH07_03900	COG1125	glycine betaine transport
CAH07_03905	COG1174	glycine betaine transport
CAH07_03910	COG1732	Glycine betaine
CAH07_03915	COG1174	glycine betaine transport
CAH07_03920	COG0840	transmembrane signaling receptor activity
CAH07_03925	COG1733	regulation of RNA biosynthetic process
CAH07_03930	COG1396	sequence-specific DNA binding
CAH07_03935	COG1396	sequence-specific DNA binding
CAH07_03940	COG1476	TRANSCRIPTIONal
CAH07_03945	COG0596	Alpha beta hydrolase
CAH07_03950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAH07_03955	COG1647	Serine aminopeptidase, S33
CAH07_03960	COG0557	exoribonuclease II activity
CAH07_03965	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CAH07_03975	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_03980	COG1309	transcriptional regulator
CAH07_03985	COG2076	Multidrug Resistance protein
CAH07_03995	COG1289	transmembrane transporter activity
CAH07_04000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CAH07_04005	COG0673	inositol 2-dehydrogenase activity
CAH07_04010	COG1937	Protein conserved in bacteria
CAH07_04015	COG2608	mercury ion transmembrane transporter activity
CAH07_04020	COG2217	Heavy metal translocating P-type atpase
CAH07_04025	COG2217	Heavy metal translocating P-type atpase
CAH07_04030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CAH07_04035	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CAH07_04040	COG2860	membrane
CAH07_04045	COG3973	AAA domain
CAH07_04050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CAH07_04055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAH07_04060	COG0025	NhaP-type Na H and K H
CAH07_04070	COG0656	L-ascorbic acid biosynthetic process
CAH07_04075	COG4149	molybdate abc transporter
CAH07_04080	COG0725	ABC transporter, periplasmic molybdate-binding protein
CAH07_04085	COG1910	domain protein
CAH07_04090	COG1368	sulfuric ester hydrolase activity
CAH07_04095	COG1988	membrane-bound metal-dependent
CAH07_04110	COG0531	amino acid
CAH07_04120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CAH07_04125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAH07_04130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAH07_04135	COG1120	ATPase activity
CAH07_04140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAH07_04145	COG1136	(ABC) transporter
CAH07_04150	COG0577	efflux transmembrane transporter activity
CAH07_04160	COG2140	Oxalate decarboxylase
CAH07_04170	COG1191	sigma factor activity
CAH07_04180	COG0745	RESPONSE REGULATOR receiver
CAH07_04185	COG2205	protein histidine kinase activity
CAH07_04190	COG3386	PFAM SMP-30 Gluconolaconase
CAH07_04195	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_04200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CAH07_04205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAH07_04210	COG1120	ATPase activity
CAH07_04215	COG2096	Adenosyltransferase
CAH07_04220	COG2814	Major facilitator Superfamily
CAH07_04225	COG4758	membrane
CAH07_04230	COG1842	Phage shock protein A
CAH07_04235	COG3595	metallopeptidase activity
CAH07_04240	COG4758	membrane
CAH07_04245	COG4585	Histidine kinase
CAH07_04250	COG2197	response regulator
CAH07_04260	COG0814	amino acid
CAH07_04265	COG0697	spore germination
CAH07_04275	COG0114	fumarate hydratase activity
CAH07_04280	COG1309	transcriptional regulator
CAH07_04290	COG2205	protein histidine kinase activity
CAH07_04290	COG2770	Histidine kinase
CAH07_04295	COG0745	RESPONSE REGULATOR receiver
CAH07_04300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAH07_04305	COG0783	Belongs to the Dps family
CAH07_04310	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_04325	COG1120	ATPase activity
CAH07_04335	COG0583	DNA-binding transcription factor activity
CAH07_04340	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_04345	COG1942	4-Oxalocrotonate Tautomerase
CAH07_04350	COG0477	Major facilitator Superfamily
CAH07_04355	COG1846	Transcriptional regulator
CAH07_04360	COG5577	PFAM Coat F domain
CAH07_04370	COG0506	proline dehydrogenase activity
CAH07_04380	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAH07_04380	COG1024	Enoyl-CoA hydratase
CAH07_04385	COG0183	Belongs to the thiolase family
CAH07_04390	COG1960	acyl-CoA dehydrogenase activity
CAH07_04395	COG1393	Belongs to the ArsC family
CAH07_04400	COG0509	glycine decarboxylation via glycine cleavage system
CAH07_04410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CAH07_04415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAH07_04425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CAH07_04430	COG2011	ABC-type metal ion transport system permease component
CAH07_04435	COG1464	Belongs to the NlpA lipoprotein family
CAH07_04440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAH07_04455	COG0396	ATPase activity
CAH07_04460	COG0719	Fe-S assembly protein
CAH07_04465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CAH07_04470	COG0822	iron-sulfur transferase activity
CAH07_04475	COG0719	Fe-S assembly protein
CAH07_04480	COG0640	Transcriptional regulator
CAH07_04485	COG0346	lactoylglutathione lyase activity
CAH07_04500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAH07_04505	COG0322	excinuclease ABC activity
CAH07_04510	COG2222	sugar isomerase
CAH07_04515	COG1653	transport
CAH07_04520	COG1175	transmembrane transport
CAH07_04525	COG0395	ABC-type sugar transport system, permease component
CAH07_04530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAH07_04535	COG2188	Transcriptional regulator
CAH07_04540	COG3842	ATPase activity
CAH07_04545	COG2356	endonuclease I
CAH07_04550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAH07_04555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CAH07_04560	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CAH07_04565	COG2068	MobA-Related Protein
CAH07_04570	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CAH07_04575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAH07_04580	COG2080	2 iron, 2 sulfur cluster binding
CAH07_04590	COG2351	hydroxyisourate hydrolase activity
CAH07_04595	COG3648	Uricase
CAH07_04595	COG3195	allantoin biosynthetic process
CAH07_04600	COG2233	PERMEase
CAH07_04605	COG2233	PERMEase
CAH07_04610	COG2508	Transcriptional regulator
CAH07_04615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CAH07_04625	COG1801	Protein of unknown function DUF72
CAH07_04630	COG0730	response to heat
CAH07_04635	COG0737	Belongs to the 5'-nucleotidase family
CAH07_04640	COG3377	Domain of unknown function (DUF1805)
CAH07_04650	COG0739	heme binding
CAH07_04655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CAH07_04665	COG4470	Protein conserved in bacteria
CAH07_04670	COG2445	Protein of unknown function DUF86
CAH07_04675	COG0647	UMP catabolic process
CAH07_04680	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CAH07_04685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CAH07_04690	COG0460	homoserine dehydrogenase
CAH07_04695	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CAH07_04700	COG0083	homoserine kinase activity
CAH07_04705	COG4946	Tricorn protease homolog
CAH07_04705	COG1506	peptidase
CAH07_04705	COG0823	Involved in the tonB-independent uptake of proteins
CAH07_04710	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CAH07_04715	COG4837	Protein of unknown function (DUF1462)
CAH07_04720	COG1252	NADH dehydrogenase
CAH07_04725	COG4844	belongs to the
CAH07_04730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CAH07_04735	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CAH07_04740	COG0316	Belongs to the HesB IscA family
CAH07_04745	COG0456	acetyltransferase
CAH07_04750	COG2808	Putative FMN-binding domain
CAH07_04755	COG0516	GMP reductase activity
CAH07_04765	COG0492	ferredoxin-NADP+ reductase activity
CAH07_04770	COG1252	NADH dehydrogenase
CAH07_04785	COG3584	3D domain protein
CAH07_04790	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CAH07_04795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CAH07_04800	COG2056	Na+-H+ antiporter family
CAH07_04805	COG1268	BioY protein
CAH07_04810	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CAH07_04815	COG2819	hydrolase of the alpha beta superfamily
CAH07_04820	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_04825	COG1169	isochorismate synthase
CAH07_04830	COG1021	2,3-dihydroxybenzoate-AMP ligase
CAH07_04835	COG3433	isochorismatase activity
CAH07_04835	COG1535	isochorismatase
CAH07_04840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_04845	COG3251	PFAM MbtH domain protein
CAH07_04850	COG5634	Uncharacterized conserved protein (DUF2278)
CAH07_04855	COG0686	Belongs to the AlaDH PNT family
CAH07_04860	COG2508	Transcriptional regulator
CAH07_04860	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CAH07_04870	COG4842	Belongs to the WXG100 family
CAH07_04875	COG5417	Belongs to the EsaB family
CAH07_04880	COG4499	WXG100 protein secretion system (Wss), protein YukC
CAH07_04885	COG1674	ftsk spoiiie
CAH07_04885	COG0433	COG0433 Predicted ATPase
CAH07_04890	COG1511	domain protein
CAH07_04900	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_04905	COG1418	mRNA catabolic process
CAH07_04920	COG0628	permease
CAH07_04935	COG5506	Protein of unknown function (DUF1694)
CAH07_04940	COG1335	isochorismatase
CAH07_04945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CAH07_04950	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CAH07_04965	COG0142	geranyltranstransferase activity
CAH07_04975	COG4585	Histidine kinase
CAH07_04980	COG2197	response regulator
CAH07_04985	COG2050	protein possibly involved in aromatic compounds catabolism
CAH07_04990	COG1320	monovalent cation:proton antiporter activity
CAH07_04995	COG2212	antiporter activity
CAH07_05000	COG1863	multisubunit Na H antiporter MnhE subunit
CAH07_05005	COG0651	ATP synthesis coupled electron transport
CAH07_05010	COG1006	Multisubunit Na H antiporter MnhC subunit
CAH07_05015	COG2111	Na H antiporter
CAH07_05020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CAH07_05020	COG2111	Na H antiporter
CAH07_05030	COG3493	citrate carrier protein
CAH07_05055	COG4565	transcriptional regulatory protein
CAH07_05060	COG3290	protein histidine kinase activity
CAH07_05070	COG3011	Protein conserved in bacteria
CAH07_05075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAH07_05080	COG2814	Major facilitator Superfamily
CAH07_05090	COG5018	Exonuclease
CAH07_05100	COG2205	protein histidine kinase activity
CAH07_05105	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CAH07_05115	COG2267	carboxylic ester hydrolase activity
CAH07_05120	COG1522	sequence-specific DNA binding
CAH07_05125	COG0436	Aminotransferase
CAH07_05130	COG1098	S1 RNA binding domain
CAH07_05135	COG2155	Conserved Protein
CAH07_05140	COG1979	alcohol dehydrogenase
CAH07_05145	COG1979	alcohol dehydrogenase
CAH07_05150	COG0166	Belongs to the GPI family
CAH07_05165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAH07_05180	COG2738	Putative neutral zinc metallopeptidase
CAH07_05185	COG1253	flavin adenine dinucleotide binding
CAH07_05190	COG0366	Alpha amylase catalytic
CAH07_05195	COG0432	Pfam Uncharacterised protein family UPF0047
CAH07_05210	COG0840	transmembrane signaling receptor activity
CAH07_05215	COG0840	transmembrane signaling receptor activity
CAH07_05220	COG0840	transmembrane signaling receptor activity
CAH07_05225	COG0840	transmembrane signaling receptor activity
CAH07_05235	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_05235	COG3347	Dehydrogenase
CAH07_05240	COG1349	DNA-binding transcription factor activity
CAH07_05245	COG1070	Carbohydrate kinase
CAH07_05250	COG3254	rhamnose metabolic process
CAH07_05255	COG4806	L-rhamnose isomerase
CAH07_05260	COG0673	inositol 2-dehydrogenase activity
CAH07_05265	COG0628	permease
CAH07_05270	COG1968	undecaprenyl-diphosphatase activity
CAH07_05280	COG5553	Cysteine dioxygenase type I
CAH07_05285	COG0477	Major facilitator Superfamily
CAH07_05290	COG1705	Flagellar rod assembly protein muramidase FlgJ
CAH07_05295	COG4682	membrane
CAH07_05300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CAH07_05305	COG0569	domain protein
CAH07_05315	COG1510	regulation of RNA biosynthetic process
CAH07_05325	COG1454	alcohol dehydrogenase
CAH07_05335	COG2318	DinB family
CAH07_05340	COG1585	Membrane protein implicated in regulation of membrane protease activity
CAH07_05345	COG2268	Band 7 protein
CAH07_05350	COG1247	-acetyltransferase
CAH07_05355	COG3859	Proton-coupled thiamine transporter YuaJ
CAH07_05480	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAH07_05485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CAH07_05490	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CAH07_05495	COG0297	glycogen (starch) synthase activity
CAH07_05500	COG0058	SHG alpha-glucan phosphorylase activity
CAH07_05505	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CAH07_05510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CAH07_05515	COG0438	transferase activity, transferring glycosyl groups
CAH07_05520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CAH07_05530	COG0438	transferase activity, transferring glycosyl groups
CAH07_05535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAH07_05540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CAH07_05545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CAH07_05550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CAH07_05555	COG1169	isochorismate synthase
CAH07_05560	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CAH07_05565	COG0596	Alpha beta hydrolase
CAH07_05570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CAH07_05575	COG0318	PFAM AMP-dependent synthetase and ligase
CAH07_05580	COG4948	Mandelate Racemase Muconate Lactonizing
CAH07_05585	COG0803	Belongs to the bacterial solute-binding protein 9 family
CAH07_05590	COG1121	(ABC) transporter
CAH07_05595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CAH07_05595	COG1321	iron dependent repressor
CAH07_05600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CAH07_05610	COG1294	oxidase, subunit
CAH07_05615	COG1271	oxidase subunit
CAH07_05620	COG0254	rRNA binding
CAH07_05625	COG0288	reversible hydration of carbon dioxide
CAH07_05630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CAH07_05635	COG1854	S-ribosylhomocysteine lyase activity
CAH07_05650	COG0783	Belongs to the Dps family
CAH07_05655	COG4824	toxin secretion phage lysis holin
CAH07_05660	COG0494	nUDIX hydrolase
CAH07_05665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAH07_05670	COG1116	anion transmembrane transporter activity
CAH07_05675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAH07_05680	COG1506	peptidase
CAH07_05690	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CAH07_05695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CAH07_05700	COG0367	asparagine synthase
CAH07_05705	COG1113	amino acid transport
CAH07_05710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CAH07_05715	COG2267	carboxylic ester hydrolase activity
CAH07_05725	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CAH07_05730	COG1242	4 iron, 4 sulfur cluster binding
CAH07_05740	COG1725	Transcriptional regulator
CAH07_05745	COG1131	(ABC) transporter
CAH07_05760	COG1136	(ABC) transporter
CAH07_05765	COG0577	efflux transmembrane transporter activity
CAH07_05770	COG0745	RESPONSE REGULATOR receiver
CAH07_05775	COG2205	protein histidine kinase activity
CAH07_05780	COG1136	(ABC) transporter
CAH07_05785	COG0577	efflux transmembrane transporter activity
CAH07_05790	COG2433	Pfam Transposase IS66
CAH07_05795	COG2814	Major facilitator Superfamily
CAH07_05800	COG2202	Pas domain
CAH07_05800	COG1366	Belongs to the anti-sigma-factor antagonist family
CAH07_05810	COG0495	leucyl-tRNA aminoacylation
CAH07_05815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CAH07_05820	COG1486	melibiose metabolic process
CAH07_05845	COG1073	alpha beta
CAH07_05855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAH07_05860	COG0156	8-amino-7-oxononanoate synthase activity
CAH07_05870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CAH07_05875	COG2124	cytochrome p450
CAH07_05880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAH07_05885	COG0395	ABC-type sugar transport system, permease component
CAH07_05890	COG1653	transport
CAH07_05895	COG2207	Transcriptional regulator
CAH07_05900	COG4209	transmembrane transport
CAH07_05905	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CAH07_05910	COG1653	transport
CAH07_05915	COG0673	inositol 2-dehydrogenase activity
CAH07_05920	COG5578	integral membrane protein
CAH07_05930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CAH07_05935	COG2081	HI0933 family
CAH07_05940	COG2244	polysaccharide biosynthetic process
CAH07_05945	COG1187	pseudouridine synthase activity
CAH07_05950	COG1349	DNA-binding transcription factor activity
CAH07_05955	COG1131	(ABC) transporter
CAH07_05960	COG4473	ABC transporter
CAH07_05965	COG2252	PERMEase
CAH07_05970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAH07_05975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CAH07_05980	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CAH07_05990	COG1597	lipid kinase activity
CAH07_05995	COG1523	belongs to the glycosyl hydrolase 13 family
CAH07_06000	COG0510	thiamine kinase activity
CAH07_06010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CAH07_06015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAH07_06020	COG0281	malic enzyme
CAH07_06025	COG5584	Small secreted protein
CAH07_06030	COG1363	Peptidase, m42
CAH07_06040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAH07_06045	COG4848	Belongs to the UPF0354 family
CAH07_06050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAH07_06055	COG1674	ftsk spoiiie
CAH07_06060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CAH07_06065	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CAH07_06070	COG4980	gas vesicle protein
CAH07_06075	COG3118	belongs to the thioredoxin family
CAH07_06080	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CAH07_06080	COG1605	Chorismate mutase
CAH07_06085	COG1609	Transcriptional regulator
CAH07_06090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CAH07_06095	COG1360	Flagellar Motor Protein
CAH07_06100	COG0123	including yeast histone deacetylase and acetoin utilization protein
CAH07_06105	COG0517	IMP dehydrogenase activity
CAH07_06110	COG0454	-acetyltransferase
CAH07_06115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAH07_06125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CAH07_06130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CAH07_06140	COG2203	Gaf domain
CAH07_06140	COG2199	diguanylate cyclase activity
CAH07_06145	COG1956	GAF domain-containing protein
CAH07_06150	COG1309	transcriptional regulator
CAH07_06155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CAH07_06160	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CAH07_06165	COG1114	Component of the transport system for branched-chain amino acids
CAH07_06170	COG1104	cysteine desulfurase activity
CAH07_06175	COG0301	tRNA thio-modification
CAH07_06185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAH07_06190	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CAH07_06195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CAH07_06200	COG0616	signal peptide processing
CAH07_06205	COG1714	RDD family
CAH07_06215	COG3874	Sporulation protein YtfJ
CAH07_06220	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CAH07_06225	COG0827	DNA restriction-modification system
CAH07_06235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CAH07_06240	COG0521	Mo-molybdopterin cofactor biosynthetic process
CAH07_06245	COG0137	argininosuccinate synthase activity
CAH07_06250	COG0165	Argininosuccinate lyase
CAH07_06260	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_06265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CAH07_06270	COG0583	DNA-binding transcription factor activity
CAH07_06275	COG0454	-acetyltransferase
CAH07_06280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAH07_06285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAH07_06290	COG0765	amino acid transport
CAH07_06295	COG0765	amino acid transport
CAH07_06300	COG1126	abc transporter atp-binding protein
CAH07_06305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAH07_06310	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CAH07_06315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAH07_06320	COG0196	riboflavin kinase activity
CAH07_06325	COG1473	amidohydrolase
CAH07_06330	COG0730	response to heat
CAH07_06335	COG4109	DRTGG domain
CAH07_06345	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CAH07_06365	COG0587	DNA-directed DNA polymerase activity
CAH07_06370	COG0281	malic enzyme
CAH07_06375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CAH07_06380	COG0825	malonyl-CoA metabolic process
CAH07_06385	COG0205	6-phosphofructokinase activity
CAH07_06390	COG0469	pyruvate kinase activity
CAH07_06395	COG3030	protein affecting phage T7 exclusion by the F plasmid
CAH07_06400	COG0628	permease
CAH07_06405	COG2707	UPF0756 membrane protein
CAH07_06410	COG0372	Belongs to the citrate synthase family
CAH07_06415	COG0538	isocitrate dehydrogenase activity
CAH07_06420	COG0039	L-malate dehydrogenase activity
CAH07_06425	COG0745	RESPONSE REGULATOR receiver
CAH07_06430	COG5002	protein histidine kinase activity
CAH07_06435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAH07_06435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAH07_06440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CAH07_06445	COG1971	Probably functions as a manganese efflux pump
CAH07_06450	COG0237	dephospho-CoA kinase activity
CAH07_06455	COG0656	L-ascorbic acid biosynthetic process
CAH07_06460	COG2814	Major facilitator Superfamily
CAH07_06465	COG1733	regulation of RNA biosynthetic process
CAH07_06470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CAH07_06475	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CAH07_06480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CAH07_06485	COG3611	Membrane attachment protein
CAH07_06490	COG1484	DNA-dependent DNA replication
CAH07_06495	COG0398	Pfam SNARE associated Golgi protein
CAH07_06505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CAH07_06515	COG3275	phosphorelay sensor kinase activity
CAH07_06520	COG3279	Response regulator of the LytR AlgR family
CAH07_06525	COG1380	Effector of murein hydrolase LrgA
CAH07_06530	COG1346	cytolysis
CAH07_06540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CAH07_06545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CAH07_06550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CAH07_06555	COG3326	Membrane
CAH07_06565	COG1363	Peptidase, m42
CAH07_06570	COG3507	Belongs to the glycosyl hydrolase 43 family
CAH07_06575	COG2160	L-arabinose isomerase activity
CAH07_06580	COG1069	ribulokinase activity
CAH07_06585	COG0235	Class ii aldolase
CAH07_06590	COG0647	UMP catabolic process
CAH07_06595	COG0371	Dehydrogenase
CAH07_06600	COG1653	transport
CAH07_06605	COG1175	transmembrane transport
CAH07_06610	COG0395	ABC-type sugar transport system, permease component
CAH07_06615	COG3534	alpha-L-arabinofuranosidase
CAH07_06620	COG1966	Carbon starvation protein
CAH07_06630	COG0346	lactoylglutathione lyase activity
CAH07_06635	COG0247	lactate metabolic process
CAH07_06640	COG0277	FAD linked oxidase domain protein
CAH07_06645	COG3835	regulator
CAH07_06655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAH07_06665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CAH07_06670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAH07_06670	COG0072	phenylalanine-tRNA ligase activity
CAH07_06675	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CAH07_06680	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CAH07_06685	COG1286	toxin biosynthetic process
CAH07_06690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CAH07_06690	COG1796	DNA polymerase
CAH07_06695	COG1193	negative regulation of DNA recombination
CAH07_06700	COG3766	membrane
CAH07_06705	COG0318	PFAM AMP-dependent synthetase and ligase
CAH07_06710	COG1309	transcriptional regulator
CAH07_06715	COG1024	Enoyl-CoA hydratase
CAH07_06720	COG2086	electron transfer activity
CAH07_06725	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CAH07_06730	COG3534	alpha-L-arabinofuranosidase
CAH07_06740	COG3118	belongs to the thioredoxin family
CAH07_06745	COG0322	excinuclease ABC activity
CAH07_06755	COG0527	aspartate kinase activity
CAH07_06760	COG1719	4-vinyl reductase, 4VR
CAH07_06765	COG2009	succinate dehydrogenase
CAH07_06770	COG1053	succinate dehydrogenase
CAH07_06775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CAH07_06780	COG0824	Thioesterase
CAH07_06785	COG2197	response regulator
CAH07_06790	COG1846	Transcriptional regulator
CAH07_06795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CAH07_06800	COG5401	PFAM Sporulation and spore germination
CAH07_06805	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CAH07_06810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CAH07_06815	COG0622	Phosphoesterase
CAH07_06825	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CAH07_06840	COG0454	-acetyltransferase
CAH07_06855	COG0028	Belongs to the TPP enzyme family
CAH07_06860	COG0440	acetolactate synthase activity
CAH07_06865	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CAH07_06870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAH07_06875	COG0473	3-isopropylmalate dehydrogenase activity
CAH07_06880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CAH07_06885	COG0066	3-isopropylmalate dehydratase activity
CAH07_06890	COG1477	protein flavinylation
CAH07_06890	COG0457	Tetratricopeptide repeat
CAH07_06895	COG0544	peptidyl-prolyl cis-trans isomerase activity
CAH07_06900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CAH07_06905	COG0470	DNA polymerase III
CAH07_06905	COG1067	ATP-dependent peptidase activity
CAH07_06910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CAH07_06915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CAH07_06925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CAH07_06930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAH07_06935	COG0181	hydroxymethylbilane synthase activity
CAH07_06940	COG1587	Uroporphyrinogen-III synthase
CAH07_06945	COG0113	porphobilinogen synthase activity
CAH07_06950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CAH07_06955	COG1388	LysM domain
CAH07_06960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CAH07_06970	COG0525	valine-tRNA ligase activity
CAH07_06975	COG0285	dihydrofolate synthase activity
CAH07_06980	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CAH07_06990	COG0424	maF-like protein
CAH07_06995	COG2003	Belongs to the UPF0758 family
CAH07_07000	COG1077	Cell shape determining protein MreB Mrl
CAH07_07005	COG1792	Involved in formation and maintenance of cell shape
CAH07_07010	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CAH07_07015	COG0850	regulation of cytokinetic process
CAH07_07020	COG2894	cell division
CAH07_07025	COG0739	heme binding
CAH07_07030	COG1994	Peptidase M50
CAH07_07035	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CAH07_07040	COG2868	ribosomal protein
CAH07_07045	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CAH07_07050	COG3290	protein histidine kinase activity
CAH07_07055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CAH07_07060	COG4492	Belongs to the UPF0735 family
CAH07_07065	COG0077	Prephenate dehydratase
CAH07_07070	COG1827	regulation of RNA biosynthetic process
CAH07_07075	COG1104	cysteine desulfurase activity
CAH07_07080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CAH07_07085	COG0157	Belongs to the NadC ModD family
CAH07_07090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CAH07_07095	COG1388	LysM domain
CAH07_07105	COG0217	transcriptional regulatory protein
CAH07_07110	COG1115	amino acid carrier protein
CAH07_07125	COG2112	serine threonine protein kinase
CAH07_07130	COG0673	inositol 2-dehydrogenase activity
CAH07_07135	COG2814	Major facilitator Superfamily
CAH07_07145	COG0632	four-way junction helicase activity
CAH07_07150	COG2255	four-way junction helicase activity
CAH07_07160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CAH07_07165	COG0343	queuine tRNA-ribosyltransferase activity
CAH07_07170	COG1862	Preprotein translocase
CAH07_07180	COG2323	membrane
CAH07_07185	COG2244	polysaccharide biosynthetic process
CAH07_07195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAH07_07195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAH07_07200	COG0490	domain, Protein
CAH07_07205	COG5416	Lipopolysaccharide assembly protein A domain
CAH07_07210	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CAH07_07210	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CAH07_07215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CAH07_07220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAH07_07225	COG1490	D-aminoacyl-tRNA deacylase activity
CAH07_07230	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAH07_07230	COG3103	Sh3 type 3 domain protein
CAH07_07230	COG4991	sh3 domain protein
CAH07_07240	COG0124	histidyl-tRNA synthetase
CAH07_07245	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CAH07_07255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CAH07_07260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CAH07_07265	COG1959	2 iron, 2 sulfur cluster binding
CAH07_07270	COG1104	cysteine desulfurase activity
CAH07_07275	COG0482	sulfurtransferase activity
CAH07_07280	COG0457	Tetratricopeptide repeat
CAH07_07285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CAH07_07290	COG3881	PFAM PRC-barrel domain
CAH07_07305	COG0765	amino acid transport
CAH07_07310	COG0765	amino acid transport
CAH07_07315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAH07_07320	COG1126	abc transporter atp-binding protein
CAH07_07325	COG0628	permease
CAH07_07330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CAH07_07335	COG4472	Bacterial protein of unknown function (DUF965)
CAH07_07340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CAH07_07345	COG3906	Belongs to the UPF0473 family
CAH07_07350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CAH07_07370	COG0572	uridine kinase
CAH07_07375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAH07_07380	COG0768	penicillin binding
CAH07_07395	COG2226	methyltransferase
CAH07_07400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CAH07_07405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CAH07_07410	COG0626	cystathionine gamma-synthase activity
CAH07_07420	COG2427	Protein of unknown function (DUF1641)
CAH07_07425	COG3383	formate dehydrogenase (NAD+) activity
CAH07_07430	COG5609	conserved protein (DUF2294)
CAH07_07435	COG2116	formate transmembrane transporter activity
CAH07_07445	COG2226	methyltransferase
CAH07_07450	COG1309	transcriptional regulator
CAH07_07455	COG2124	cytochrome p450
CAH07_07455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CAH07_07465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CAH07_07465	COG2755	lipolytic protein G-D-S-L family
CAH07_07475	COG1595	DNA-templated transcription, initiation
CAH07_07480	COG1378	Sugar-specific transcriptional regulator TrmB
CAH07_07485	COG1280	lysine exporter protein (LysE YggA)
CAH07_07490	COG1113	amino acid transport
CAH07_07495	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CAH07_07495	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CAH07_07500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAH07_07505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAH07_07510	COG3715	PTS system
CAH07_07515	COG3716	PTS system mannose fructose sorbose family IID component
CAH07_07520	COG1621	beta-fructofuranosidase activity
CAH07_07525	COG0693	protein deglycase activity
CAH07_07530	COG1064	alcohol dehydrogenase
CAH07_07540	COG0789	Transcriptional regulator
CAH07_07545	COG5577	PFAM Coat F domain
CAH07_07555	COG1063	alcohol dehydrogenase
CAH07_07560	COG5577	PFAM Coat F domain
CAH07_07570	COG0346	lactoylglutathione lyase activity
CAH07_07575	COG4991	sh3 domain protein
CAH07_07580	COG4991	sh3 domain protein
CAH07_07585	COG0596	Alpha beta hydrolase
CAH07_07590	COG5566	PFAM Mor transcription activator
CAH07_07595	COG3409	Peptidoglycan-binding domain 1 protein
CAH07_07600	COG2828	Protein conserved in bacteria
CAH07_07605	COG0583	DNA-binding transcription factor activity
CAH07_07610	COG2851	Citrate transporter
CAH07_07615	COG0667	Aldo Keto reductase
CAH07_07620	COG1595	DNA-templated transcription, initiation
CAH07_07625	COG3443	Belongs to the bacterial solute-binding protein 9 family
CAH07_07655	COG2070	2-Nitropropane dioxygenase
CAH07_07665	COG2318	DinB family
CAH07_07675	COG1335	isochorismatase
CAH07_07685	COG2124	cytochrome p450
CAH07_07695	COG1522	sequence-specific DNA binding
CAH07_07700	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CAH07_07705	COG1687	branched-chain amino acid
CAH07_07710	COG1114	Component of the transport system for branched-chain amino acids
CAH07_07720	COG0583	DNA-binding transcription factor activity
CAH07_07725	COG1942	4-Oxalocrotonate Tautomerase
CAH07_07730	COG1230	cation diffusion facilitator family transporter
CAH07_07735	COG2072	flavoprotein involved in K transport
CAH07_07740	COG0583	DNA-binding transcription factor activity
CAH07_07745	COG0697	spore germination
CAH07_07755	COG1253	flavin adenine dinucleotide binding
CAH07_07760	COG0456	acetyltransferase
CAH07_07765	COG2814	Major facilitator Superfamily
CAH07_07770	COG0789	Transcriptional regulator
CAH07_07770	COG4978	Transcriptional regulator
CAH07_07785	COG0662	Cupin 2, conserved barrel domain protein
CAH07_07800	COG1937	Protein conserved in bacteria
CAH07_07805	COG2210	Belongs to the sulfur carrier protein TusA family
CAH07_07815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CAH07_07815	COG0425	Belongs to the sulfur carrier protein TusA family
CAH07_07830	COG0425	Belongs to the sulfur carrier protein TusA family
CAH07_07835	COG0730	response to heat
CAH07_07845	COG2249	NAD(P)H dehydrogenase (quinone) activity
CAH07_07850	COG0454	-acetyltransferase
CAH07_07855	COG2311	Membrane
CAH07_07860	COG0745	RESPONSE REGULATOR receiver
CAH07_07865	COG0642	Histidine kinase
CAH07_07865	COG5002	protein histidine kinase activity
CAH07_07870	COG3223	Belongs to the PsiE family
CAH07_07880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CAH07_07890	COG2856	Zn peptidase
CAH07_07895	COG0563	adenylate kinase activity
CAH07_07905	COG3620	sequence-specific DNA binding
CAH07_07910	COG1476	TRANSCRIPTIONal
CAH07_07935	COG5377	YqaJ viral recombinase family
CAH07_07940	COG3723	Recombinational DNA repair protein, rece pathway
CAH07_07945	COG3935	DnaD domain protein
CAH07_07950	COG1484	DNA-dependent DNA replication
CAH07_07960	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CAH07_07975	COG3677	Transposase
CAH07_07985	COG5484	DNA packaging
CAH07_07990	COG1783	phage Terminase large subunit
CAH07_07995	COG5518	Phage portal protein
CAH07_08000	COG2369	cell adhesion
CAH07_08010	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CAH07_08015	COG4653	Phage capsid family
CAH07_08080	COG3953	SLT domain
CAH07_08080	COG5280	Phage tail tape measure protein TP901
CAH07_08085	COG1652	LysM domain
CAH07_08090	COG4193	domain, Protein
CAH07_08100	COG3628	GPW Gp25 family protein
CAH07_08105	COG3299	homolog of phage Mu protein gp47
CAH07_08110	COG3778	Protein conserved in bacteria
CAH07_08140	COG4824	toxin secretion phage lysis holin
CAH07_08145	COG3409	Peptidoglycan-binding domain 1 protein
CAH07_08145	COG5632	N-Acetylmuramoyl-L-alanine amidase
CAH07_08165	COG5444	nuclease activity
CAH07_08180	COG0457	Tetratricopeptide repeat
CAH07_08185	COG3403	YqcI/YcgG family
CAH07_08190	COG0640	Transcriptional regulator
CAH07_08195	COG0346	lactoylglutathione lyase activity
CAH07_08200	COG0798	PFAM Bile acid sodium symporter
CAH07_08205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CAH07_08215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CAH07_08225	COG3209	COG3209 Rhs family protein
CAH07_08235	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CAH07_08240	COG0398	Pfam SNARE associated Golgi protein
CAH07_08245	COG5632	N-Acetylmuramoyl-L-alanine amidase
CAH07_08245	COG3409	Peptidoglycan-binding domain 1 protein
CAH07_08250	COG2755	lipolytic protein G-D-S-L family
CAH07_08260	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CAH07_08265	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CAH07_08270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CAH07_08275	COG1534	Rna-binding protein
CAH07_08280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CAH07_08285	COG1713	HD superfamily hydrolase involved in NAD metabolism
CAH07_08290	COG0799	negative regulation of ribosome biogenesis
CAH07_08295	COG2226	methyltransferase
CAH07_08300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CAH07_08305	COG1596	polysaccharide export
CAH07_08305	COG1555	photosystem II stabilization
CAH07_08310	COG2131	deaminase
CAH07_08315	COG2333	competence protein COMEC
CAH07_08315	COG0658	competence protein
CAH07_08325	COG1466	dna polymerase III delta subunit
CAH07_08330	COG0268	Binds directly to 16S ribosomal RNA
CAH07_08335	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CAH07_08340	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAH07_08350	COG0481	GTPase activity
CAH07_08355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CAH07_08360	COG1420	regulation of RNA biosynthetic process
CAH07_08365	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CAH07_08370	COG0443	Heat shock 70 kDa protein
CAH07_08375	COG0484	heat shock protein binding
CAH07_08380	COG2264	protein methyltransferase activity
CAH07_08385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CAH07_08390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CAH07_08395	COG1283	sodium-dependent phosphate transmembrane transporter activity
CAH07_08400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CAH07_08405	COG1610	YqeY-like protein
CAH07_08410	COG1030	water channel activity
CAH07_08415	COG4864	UPF0365 protein
CAH07_08430	COG0561	phosphatase activity
CAH07_08435	COG1702	phosphate starvation-inducible protein PhoH
CAH07_08440	COG1480	7TM receptor with intracellular HD hydrolase
CAH07_08445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CAH07_08450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CAH07_08455	COG0295	cytidine deaminase activity
CAH07_08460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CAH07_08470	COG1381	Involved in DNA repair and RecF pathway recombination
CAH07_08475	COG0752	glycyl-tRNA synthetase alpha subunit
CAH07_08480	COG0751	glycine-tRNA ligase activity
CAH07_08485	COG0517	IMP dehydrogenase activity
CAH07_08490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CAH07_08495	COG1671	Belongs to the UPF0178 family
CAH07_08500	COG0358	DNA primase activity
CAH07_08505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CAH07_08515	COG2010	Cytochrome c
CAH07_08520	COG2384	SAM-dependent methyltransferase
CAH07_08525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CAH07_08530	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CAH07_08540	COG0513	Belongs to the DEAD box helicase family
CAH07_08545	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CAH07_08555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CAH07_08560	COG0735	belongs to the Fur family
CAH07_08565	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CAH07_08570	COG4709	membrane
CAH07_08575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CAH07_08580	COG1388	LysM domain
CAH07_08585	COG5521	maltodextrose utilization protein MalA
CAH07_08590	COG2839	Protein conserved in bacteria
CAH07_08595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CAH07_08600	COG0477	Major facilitator Superfamily
CAH07_08610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CAH07_08615	COG0573	inorganic phosphate transmembrane transporter activity
CAH07_08620	COG0581	inorganic phosphate transmembrane transporter activity
CAH07_08625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CAH07_08630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CAH07_08635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CAH07_08650	COG0438	transferase activity, transferring glycosyl groups
CAH07_08655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CAH07_08660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CAH07_08670	COG0457	Tetratricopeptide repeat
CAH07_08670	COG0705	Rhomboid family
CAH07_08675	COG4483	Protein conserved in bacteria
CAH07_08680	COG1940	carbohydrate kinase activity
CAH07_08685	COG1368	sulfuric ester hydrolase activity
CAH07_08690	COG2866	Carboxypeptidase
CAH07_08700	COG0011	TIGRFAM Protein of
CAH07_08710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAH07_08720	COG1393	Belongs to the ArsC family
CAH07_08730	COG1366	Belongs to the anti-sigma-factor antagonist family
CAH07_08735	COG1253	flavin adenine dinucleotide binding
CAH07_08740	COG0598	Magnesium transport protein CorA
CAH07_08750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CAH07_08755	COG1459	type II secretion system
CAH07_08760	COG4537	Required for transformation and DNA binding
CAH07_08765	COG4970	Tfp pilus assembly protein FimT
CAH07_08775	COG4940	Competence protein ComGF
CAH07_08800	COG0681	Belongs to the peptidase S26 family
CAH07_08810	COG1396	sequence-specific DNA binding
CAH07_08825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CAH07_08830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CAH07_08835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAH07_08840	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAH07_08845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CAH07_08850	COG0095	Lipoate-protein ligase
CAH07_08855	COG1321	iron dependent repressor
CAH07_08860	COG1752	Esterase of the alpha-beta hydrolase superfamily
CAH07_08870	COG3872	metal-dependent enzyme
CAH07_08880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CAH07_08885	COG0006	proline dipeptidase activity
CAH07_08890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CAH07_08900	COG3854	ATPases associated with a variety of cellular activities
CAH07_08940	COG0511	ligase activity, forming carbon-carbon bonds
CAH07_08945	COG0439	Biotin carboxylase
CAH07_08950	COG1302	Protein conserved in bacteria
CAH07_08955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAH07_08960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CAH07_08965	COG1570	exodeoxyribonuclease VII activity
CAH07_08970	COG1722	exodeoxyribonuclease VII activity
CAH07_08975	COG0142	geranyltranstransferase activity
CAH07_08980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CAH07_08985	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CAH07_08990	COG1438	arginine binding
CAH07_08995	COG0497	DNA recombination
CAH07_09000	COG0750	zinc metalloprotease
CAH07_09005	COG0745	RESPONSE REGULATOR receiver
CAH07_09010	COG1902	pentaerythritol trinitrate reductase activity
CAH07_09020	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAH07_09025	COG0584	glycerophosphoryl diester phosphodiesterase
CAH07_09030	COG0183	Belongs to the thiolase family
CAH07_09035	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAH07_09040	COG1960	acyl-CoA dehydrogenase activity
CAH07_09045	COG0372	Belongs to the citrate synthase family
CAH07_09050	COG2079	MmgE PrpD family protein
CAH07_09055	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CAH07_09065	COG3290	protein histidine kinase activity
CAH07_09065	COG3829	transcription factor binding
CAH07_09070	COG0280	phosphate acetyltransferase
CAH07_09075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CAH07_09080	COG3426	butyrate kinase activity
CAH07_09085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAH07_09090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CAH07_09095	COG0022	dehydrogenase e1 component
CAH07_09100	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAH07_09105	COG4978	Transcriptional regulator
CAH07_09105	COG0789	Transcriptional regulator
CAH07_09110	COG2814	Major facilitator Superfamily
CAH07_09115	COG1597	lipid kinase activity
CAH07_09125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAH07_09130	COG0765	amino acid transport
CAH07_09135	COG1126	abc transporter atp-binding protein
CAH07_09140	COG4129	membrane
CAH07_09145	COG1376	ErfK ybiS ycfS ynhG family protein
CAH07_09150	COG0346	lactoylglutathione lyase activity
CAH07_09155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CAH07_09160	COG2195	Cleaves the N-terminal amino acid of tripeptides
CAH07_09165	COG3361	conserved protein (COG2071)
CAH07_09170	COG0706	membrane insertase activity
CAH07_09180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CAH07_09185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CAH07_09190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CAH07_09195	COG1234	tRNA 3'-trailer cleavage
CAH07_09205	COG0596	Alpha beta hydrolase
CAH07_09210	COG1902	pentaerythritol trinitrate reductase activity
CAH07_09215	COG4187	Peptidase family M20/M25/M40
CAH07_09220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CAH07_09225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAH07_09230	COG0300	oxidoreductase activity
CAH07_09235	COG3048	D-serine ammonia-lyase activity
CAH07_09240	COG1072	(Pantothenic acid kinase))
CAH07_09245	COG0346	lactoylglutathione lyase activity
CAH07_09255	COG2211	Major facilitator Superfamily
CAH07_09265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CAH07_09275	COG0456	acetyltransferase
CAH07_09280	COG2329	Antibiotic biosynthesis monooxygenase
CAH07_09285	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CAH07_09285	COG0456	acetyltransferase
CAH07_09290	COG4918	Iron-sulphur cluster biosynthesis
CAH07_09300	COG1073	alpha beta
CAH07_09310	COG0667	Aldo Keto reductase
CAH07_09320	COG0494	nUDIX hydrolase
CAH07_09325	COG1379	DNA repair
CAH07_09330	COG1396	sequence-specific DNA binding
CAH07_09335	COG0252	asparaginase activity
CAH07_09340	COG1027	Aspartate ammonia-lyase
CAH07_09345	COG1757	Na H antiporter
CAH07_09350	COG0281	malic enzyme
CAH07_09360	COG1300	Membrane
CAH07_09365	COG0735	belongs to the Fur family
CAH07_09375	COG4974	Belongs to the 'phage' integrase family
CAH07_09380	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CAH07_09385	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CAH07_09390	COG1686	Belongs to the peptidase S11 family
CAH07_09395	COG1366	Belongs to the anti-sigma-factor antagonist family
CAH07_09400	COG2172	sigma factor antagonist activity
CAH07_09405	COG1191	sigma factor activity
CAH07_09425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAH07_09440	COG0697	spore germination
CAH07_09445	COG0019	diaminopimelate decarboxylase activity
CAH07_09450	COG4086	secreted protein
CAH07_09460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CAH07_09480	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
CAH07_09490	COG0681	Belongs to the peptidase S26 family
CAH07_09500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAH07_09500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAH07_09505	COG0307	riboflavin synthase, alpha
CAH07_09510	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CAH07_09510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CAH07_09515	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CAH07_09520	COG0456	acetyltransferase
CAH07_09525	COG1547	Domain of unknown function (DUF309)
CAH07_09530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CAH07_09535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CAH07_09545	COG1686	Belongs to the peptidase S11 family
CAH07_09550	COG2715	membrane protein required for spore maturation
CAH07_09555	COG0700	Nucleoside recognition
CAH07_09560	COG1187	pseudouridine synthase activity
CAH07_09565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAH07_09570	COG1333	cytochrome c biogenesis protein
CAH07_09575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAH07_09580	COG0745	RESPONSE REGULATOR receiver
CAH07_09585	COG5002	protein histidine kinase activity
CAH07_09590	COG1595	DNA-templated transcription, initiation
CAH07_09600	COG0710	3-dehydroquinate dehydratase activity
CAH07_09605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAH07_09610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CAH07_09615	COG1141	Ferredoxin
CAH07_09620	COG4955	Helix-turn-helix domain
CAH07_09625	COG0514	ATP-dependent DNA helicase (RecQ)
CAH07_09630	COG1266	CAAX protease self-immunity
CAH07_09635	COG1388	LysM domain
CAH07_09645	COG1408	metallophosphoesterase
CAH07_09650	COG4862	establishment of competence for transformation
CAH07_09655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CAH07_09660	COG0492	ferredoxin-NADP+ reductase activity
CAH07_09665	COG2339	peptidase activity
CAH07_09670	COG3773	Cell wall hydrolase
CAH07_09670	COG3409	Peptidoglycan-binding domain 1 protein
CAH07_09675	COG2959	enzyme of heme biosynthesis
CAH07_09680	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CAH07_09690	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CAH07_09695	COG0539	negative regulation of cytoplasmic translation
CAH07_09700	COG1304	FMN binding
CAH07_09725	COG1160	GTP binding
CAH07_09730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CAH07_09745	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CAH07_09750	COG0776	regulation of translation
CAH07_09755	COG0302	gtp cyclohydrolase
CAH07_09765	COG0142	geranyltranstransferase activity
CAH07_09770	COG2226	methyltransferase
CAH07_09775	COG0142	geranyltranstransferase activity
CAH07_09780	COG0105	UTP biosynthetic process
CAH07_09785	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAH07_09790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CAH07_09795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CAH07_09800	COG4401	Chorismate mutase type I
CAH07_09805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CAH07_09810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CAH07_09820	COG0135	phosphoribosylanthranilate isomerase activity
CAH07_09825	COG0133	tryptophan synthase activity
CAH07_09835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAH07_09840	COG0287	Prephenate dehydrogenase
CAH07_09845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CAH07_09850	COG0457	Tetratricopeptide repeat
CAH07_09855	COG5582	Belongs to the UPF0302 family
CAH07_09865	COG0723	plastoquinol--plastocyanin reductase activity
CAH07_09870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CAH07_09875	COG2010	Cytochrome c
CAH07_09875	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CAH07_09880	COG4347	Protein of unknown function (DUF1405)
CAH07_09890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CAH07_09895	COG1694	Mazg nucleotide pyrophosphohydrolase
CAH07_09900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CAH07_09905	COG1803	Methylglyoxal synthase
CAH07_09910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CAH07_09915	COG0438	transferase activity, transferring glycosyl groups
CAH07_09920	COG0617	tRNA 3'-terminal CCA addition
CAH07_09925	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CAH07_09925	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CAH07_09930	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CAH07_09935	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CAH07_09940	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CAH07_09945	COG1199	ATP-dependent helicase activity
CAH07_09945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CAH07_09955	COG5353	protein conserved in bacteria
CAH07_09960	COG0436	Aminotransferase
CAH07_09965	COG0017	Asparaginyl-tRNA synthetase
CAH07_09970	COG3935	DnaD domain protein
CAH07_09975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CAH07_09985	COG4499	WXG100 protein secretion system (Wss), protein YukC
CAH07_09985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAH07_09990	COG3331	DNA recombination
CAH07_10025	COG0071	Belongs to the small heat shock protein (HSP20) family
CAH07_10030	COG2190	(PTS) system
CAH07_10035	COG1111	helicase
CAH07_10035	COG1205	dead DEAH box helicase
CAH07_10040	COG3359	exonuclease
CAH07_10050	COG4474	Belongs to the UPF0398 family
CAH07_10065	COG0116	Belongs to the methyltransferase superfamily
CAH07_10080	COG1199	ATP-dependent helicase activity
CAH07_10085	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_10090	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CAH07_10095	COG1609	Transcriptional regulator
CAH07_10100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAH07_10105	COG0800	Aldolase
CAH07_10115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CAH07_10120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CAH07_10130	COG3424	synthase
CAH07_10135	COG1755	Isoprenylcysteine carboxyl methyltransferase
CAH07_10140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CAH07_10155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAH07_10165	COG0328	RNA-DNA hybrid ribonuclease activity
CAH07_10170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CAH07_10175	COG0328	RNA-DNA hybrid ribonuclease activity
CAH07_10195	COG1278	Cold shock
CAH07_10200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CAH07_10205	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CAH07_10210	COG0386	Belongs to the glutathione peroxidase family
CAH07_10215	COG1418	mRNA catabolic process
CAH07_10220	COG1413	lyase activity
CAH07_10225	COG0129	dihydroxy-acid dehydratase activity
CAH07_10235	COG2521	methyltransferase
CAH07_10235	COG2136	Putative SAM-dependent methyltransferase
CAH07_10245	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CAH07_10250	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CAH07_10255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CAH07_10260	COG0204	Acyl-transferase
CAH07_10265	COG1272	protein, Hemolysin III
CAH07_10270	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CAH07_10275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CAH07_10285	COG1999	signal sequence binding
CAH07_10290	COG2755	lipolytic protein G-D-S-L family
CAH07_10295	COG4698	Protein conserved in bacteria
CAH07_10305	COG0534	Mate efflux family protein
CAH07_10310	COG1846	Transcriptional regulator
CAH07_10315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAH07_10320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAH07_10325	COG1086	Polysaccharide biosynthesis protein
CAH07_10330	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CAH07_10335	COG4641	Protein conserved in bacteria
CAH07_10350	COG0463	Glycosyl transferase, family 2
CAH07_10355	COG0456	acetyltransferase
CAH07_10365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAH07_10370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CAH07_10375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAH07_10380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAH07_10385	COG0456	acetyltransferase
CAH07_10390	COG1509	lysine 2,3-aminomutase activity
CAH07_10400	COG4479	Belongs to the UPF0346 family
CAH07_10425	COG0671	phosphoesterase, PA-phosphatase related
CAH07_10440	COG0813	purine-nucleoside phosphorylase activity
CAH07_10445	COG1876	peptidase activity
CAH07_10455	COG2226	methyltransferase
CAH07_10460	COG3409	Peptidoglycan-binding domain 1 protein
CAH07_10460	COG0793	Belongs to the peptidase S41A family
CAH07_10465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAH07_10475	COG0346	lactoylglutathione lyase activity
CAH07_10480	COG0400	carboxylic ester hydrolase activity
CAH07_10485	COG0778	Nitroreductase
CAH07_10490	COG1733	regulation of RNA biosynthetic process
CAH07_10495	COG1942	4-Oxalocrotonate Tautomerase
CAH07_10500	COG2610	gluconate transmembrane transporter activity
CAH07_10515	COG2962	Rard protein
CAH07_10525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CAH07_10530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CAH07_10535	COG1366	Belongs to the anti-sigma-factor antagonist family
CAH07_10540	COG0534	Mate efflux family protein
CAH07_10545	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CAH07_10550	COG1819	glycosyl
CAH07_10555	COG1388	LysM domain
CAH07_10555	COG0791	NLP P60 protein
CAH07_10560	COG2032	superoxide dismutase activity
CAH07_10565	COG0714	Associated with various cellular activities
CAH07_10570	COG4548	von Willebrand factor, type A
CAH07_10575	COG0567	Dehydrogenase, E1 component
CAH07_10580	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAH07_10585	COG0385	Bile acid
CAH07_10590	COG0733	neurotransmitter:sodium symporter activity
CAH07_10595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CAH07_10600	COG1657	PFAM Prenyltransferase squalene oxidase
CAH07_10605	COG1012	belongs to the aldehyde dehydrogenase family
CAH07_10635	COG0071	Belongs to the small heat shock protein (HSP20) family
CAH07_10650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CAH07_10655	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CAH07_10670	COG0514	ATP-dependent DNA helicase (RecQ)
CAH07_10675	COG1388	LysM domain
CAH07_10675	COG3584	3D domain protein
CAH07_10680	COG2197	response regulator
CAH07_10685	COG4585	Histidine kinase
CAH07_10690	COG3239	Fatty acid desaturase
CAH07_10695	COG1619	proteins homologs of microcin C7 resistance protein MccF
CAH07_10710	COG2322	membrane
CAH07_10715	COG0741	lytic transglycosylase activity
CAH07_10720	COG0640	Transcriptional regulator
CAH07_10730	COG2378	regulation of single-species biofilm formation
CAH07_10735	COG3708	Transcriptional regulator
CAH07_10740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAH07_10745	COG1309	transcriptional regulator
CAH07_10750	COG0456	acetyltransferase
CAH07_10755	COG0662	Cupin 2, conserved barrel domain protein
CAH07_10755	COG2207	Transcriptional regulator
CAH07_10760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAH07_10765	COG1231	oxidoreductase activity
CAH07_10770	COG4282	regulation of fungal-type cell wall biogenesis
CAH07_10775	COG5444	nuclease activity
CAH07_10785	COG1940	carbohydrate kinase activity
CAH07_10795	COG1175	transmembrane transport
CAH07_10800	COG0395	ABC-type sugar transport system, permease component
CAH07_10815	COG2723	6-phospho-beta-galactosidase activity
CAH07_10845	COG2135	peptidase activity
CAH07_10860	COG1396	sequence-specific DNA binding
CAH07_10865	COG2314	TM2 domain
CAH07_10875	COG0726	polysaccharide deacetylase
CAH07_10880	COG3848	Pyruvate phosphate dikinase
CAH07_10880	COG0574	Belongs to the PEP-utilizing enzyme family
CAH07_10900	COG2367	Beta-lactamase
CAH07_10905	COG0693	protein deglycase activity
CAH07_10915	COG0697	spore germination
CAH07_10920	COG0583	DNA-binding transcription factor activity
CAH07_10925	COG3739	integral membrane protein
CAH07_10930	COG3655	Transcriptional regulator
CAH07_10940	COG2720	vancomycin resistance protein
CAH07_10960	COG0456	acetyltransferase
CAH07_10970	COG2140	Oxalate decarboxylase
CAH07_10980	COG2135	peptidase activity
CAH07_10985	COG3866	Pectate lyase
CAH07_10990	COG3619	membrane
CAH07_10995	COG4305	rare lipoprotein A
CAH07_11000	COG2368	4-hydroxyphenylacetate
CAH07_11005	COG0840	transmembrane signaling receptor activity
CAH07_11005	COG5278	phosphoserine phosphatase activity
CAH07_11030	COG0243	molybdopterin cofactor binding
CAH07_11035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAH07_11040	COG1070	Carbohydrate kinase
CAH07_11045	COG2814	Major facilitator Superfamily
CAH07_11060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAH07_11070	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CAH07_11075	COG0300	oxidoreductase activity
CAH07_11085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CAH07_11090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CAH07_11095	COG0583	DNA-binding transcription factor activity
CAH07_11100	COG0067	glutamate synthase
CAH07_11100	COG0070	glutamate synthase
CAH07_11100	COG0069	glutamate synthase activity
CAH07_11105	COG0493	'glutamate synthase
CAH07_11110	COG0604	alcohol dehydrogenase
CAH07_11115	COG0583	DNA-binding transcription factor activity
CAH07_11120	COG0405	Gamma-glutamyltransferase
CAH07_11125	COG0166	Belongs to the GPI family
CAH07_11130	COG0582	viral genome integration into host DNA
CAH07_11145	COG0534	Mate efflux family protein
CAH07_11150	COG2017	converts alpha-aldose to the beta-anomer
CAH07_11155	COG2027	D-alanyl-D-alanine carboxypeptidase
CAH07_11160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_11165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_11170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_11175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_11180	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CAH07_11180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_11190	COG1649	PFAM Uncharacterised BCR, COG1649
CAH07_11200	COG1960	acyl-CoA dehydrogenase activity
CAH07_11205	COG0318	PFAM AMP-dependent synthetase and ligase
CAH07_11210	COG0439	Biotin carboxylase
CAH07_11215	COG0511	ligase activity, forming carbon-carbon bonds
CAH07_11220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAH07_11225	COG1024	Enoyl-CoA hydratase
CAH07_11230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CAH07_11235	COG2404	hydrolase activity, acting on ester bonds
CAH07_11240	COG0586	Pfam SNARE associated Golgi protein
CAH07_11245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CAH07_11250	COG2246	polysaccharide biosynthetic process
CAH07_11255	COG3507	Belongs to the glycosyl hydrolase 43 family
CAH07_11260	COG5520	Belongs to the glycosyl hydrolase 30 family
CAH07_11270	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CAH07_11275	COG1115	amino acid carrier protein
CAH07_11285	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CAH07_11290	COG0187	DNA topoisomerase II activity
CAH07_11295	COG1832	CoA-binding protein
CAH07_11300	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CAH07_11305	COG4841	protein insertion into membrane
CAH07_11315	COG0824	Thioesterase
CAH07_11335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAH07_11340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CAH07_11355	COG0071	Belongs to the small heat shock protein (HSP20) family
CAH07_11365	COG4846	Membrane protein involved in cytochrome C biogenesis
CAH07_11370	COG2201	protein-glutamate methylesterase activity
CAH07_11375	COG0785	Cytochrome C biogenesis protein
CAH07_11385	COG3763	UPF0154 protein
CAH07_11395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CAH07_11400	COG4224	UPF0291 protein
CAH07_11405	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CAH07_11410	COG1388	LysM domain
CAH07_11415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CAH07_11425	COG0346	lactoylglutathione lyase activity
CAH07_11435	COG4195	phage-related replication protein
CAH07_11465	COG0531	amino acid
CAH07_11470	COG0697	spore germination
CAH07_11485	COG3832	glyoxalase III activity
CAH07_11495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAH07_11530	COG0756	dUTP diphosphatase activity
CAH07_11540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CAH07_11545	COG2814	Major facilitator Superfamily
CAH07_11550	COG1525	nuclease
CAH07_11560	COG1070	Carbohydrate kinase
CAH07_11565	COG2115	Belongs to the xylose isomerase family
CAH07_11570	COG1940	carbohydrate kinase activity
CAH07_11575	COG3507	Belongs to the glycosyl hydrolase 43 family
CAH07_11580	COG2211	Major facilitator Superfamily
CAH07_11585	COG0135	phosphoribosylanthranilate isomerase activity
CAH07_11600	COG3655	Transcriptional regulator
CAH07_11615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAH07_11635	COG0463	Glycosyl transferase, family 2
CAH07_11645	COG4824	toxin secretion phage lysis holin
CAH07_11665	COG0174	glutamine synthetase
CAH07_11670	COG0789	Transcriptional regulator
CAH07_11675	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CAH07_11680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CAH07_11685	COG0464	growth
CAH07_11695	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAH07_11700	COG4112	unkown
CAH07_11705	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAH07_11710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAH07_11715	COG1780	Probably involved in ribonucleotide reductase function
CAH07_11730	COG1923	regulation of RNA biosynthetic process
CAH07_11735	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CAH07_11750	COG2076	Multidrug Resistance protein
CAH07_11755	COG2076	Multidrug Resistance protein
CAH07_11760	COG1764	response to oxidative stress
CAH07_11765	COG4195	phage-related replication protein
CAH07_11775	COG1404	Belongs to the peptidase S8 family
CAH07_11780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAH07_11790	COG2124	cytochrome p450
CAH07_11795	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CAH07_11795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CAH07_11795	COG3321	synthase
CAH07_11795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAH07_11800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_11800	COG3321	synthase
CAH07_11800	COG4221	oxidoreductase activity
CAH07_11800	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_11805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAH07_11805	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_11805	COG3321	synthase
CAH07_11805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAH07_11805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_11810	COG3321	synthase
CAH07_11810	COG4221	oxidoreductase activity
CAH07_11810	COG0300	oxidoreductase activity
CAH07_11810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAH07_11815	COG3321	synthase
CAH07_11815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_11815	COG0318	PFAM AMP-dependent synthetase and ligase
CAH07_11815	COG0300	oxidoreductase activity
CAH07_11815	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_11820	COG1024	Enoyl-CoA hydratase
CAH07_11825	COG1024	Enoyl-CoA hydratase
CAH07_11830	COG3425	synthase
CAH07_11835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CAH07_11840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAH07_11845	COG2070	2-Nitropropane dioxygenase
CAH07_11845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CAH07_11850	COG3321	synthase
CAH07_11855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CAH07_11865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAH07_11870	COG3226	Transcriptional regulator
CAH07_11885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CAH07_11890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CAH07_11900	COG4550	Control of competence regulator ComK, YlbF/YmcA
CAH07_11905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CAH07_11910	COG0156	8-amino-7-oxononanoate synthase activity
CAH07_11915	COG1063	alcohol dehydrogenase
CAH07_11920	COG2359	stage V sporulation protein S
CAH07_11925	COG1692	metallophosphoesterase
CAH07_11930	COG1418	mRNA catabolic process
CAH07_11935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CAH07_11940	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CAH07_11945	COG1058	Belongs to the CinA family
CAH07_11945	COG1546	Belongs to the CinA family
CAH07_11950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CAH07_11955	COG1426	Protein conserved in bacteria
CAH07_11970	COG0300	oxidoreductase activity
CAH07_11975	COG0612	Peptidase, M16
CAH07_11980	COG0612	Peptidase, M16
CAH07_11985	COG2814	Major facilitator Superfamily
CAH07_11990	COG2188	Transcriptional regulator
CAH07_11995	COG4980	gas vesicle protein
CAH07_11995	COG1674	ftsk spoiiie
CAH07_12005	COG0740	serine-type endopeptidase activity
CAH07_12010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CAH07_12015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAH07_12020	COG0527	aspartate kinase activity
CAH07_12025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CAH07_12030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CAH07_12035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAH07_12040	COG1873	PFAM PRC-barrel domain
CAH07_12045	COG0612	Peptidase, M16
CAH07_12050	COG0726	polysaccharide deacetylase
CAH07_12055	COG1185	polyribonucleotide nucleotidyltransferase activity
CAH07_12060	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CAH07_12065	COG0196	riboflavin kinase activity
CAH07_12070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CAH07_12075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CAH07_12080	COG1550	Protein conserved in bacteria
CAH07_12085	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CAH07_12090	COG1358	cellular component organization or biogenesis
CAH07_12095	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CAH07_12100	COG0195	Participates in both transcription termination and antitermination
CAH07_12105	COG0779	Required for maturation of 30S ribosomal subunits
CAH07_12110	COG2176	DNA-directed DNA polymerase activity
CAH07_12115	COG0442	prolyl-tRNA aminoacylation
CAH07_12120	COG0750	zinc metalloprotease
CAH07_12125	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CAH07_12130	COG4589	Belongs to the CDS family
CAH07_12135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CAH07_12140	COG0233	cytoplasmic translational termination
CAH07_12145	COG0528	UMP kinase activity
CAH07_12150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CAH07_12155	COG0052	Belongs to the universal ribosomal protein uS2 family
CAH07_12165	COG1191	sigma factor activity
CAH07_12170	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CAH07_12175	COG1776	CheC inhibitor of MCP methylation
CAH07_12180	COG0835	chemotaxis
CAH07_12185	COG2198	Histidine kinase
CAH07_12185	COG0643	Histidine kinase
CAH07_12190	COG2201	protein-glutamate methylesterase activity
CAH07_12195	COG0455	bacterial-type flagellum organization
CAH07_12200	COG1419	protein localization to endoplasmic reticulum
CAH07_12205	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAH07_12210	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAH07_12215	COG1684	flagellar biosynthetic protein fliR
CAH07_12220	COG1987	bacterial-type flagellum assembly
CAH07_12225	COG1338	Plays a role in the flagellum-specific transport system
CAH07_12230	COG3190	flagellar
CAH07_12235	COG2201	protein-glutamate methylesterase activity
CAH07_12240	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAH07_12240	COG1776	CheC inhibitor of MCP methylation
CAH07_12245	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAH07_12250	COG1580	Controls the rotational direction of flagella during chemotaxis
CAH07_12255	COG1582	Flagellar protein (FlbD)
CAH07_12260	COG4786	Flagellar basal body rod
CAH07_12265	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CAH07_12270	COG3144	bacterial-type flagellum assembly
CAH07_12275	COG3334	PFAM MgtE intracellular
CAH07_12280	COG2882	bacterial-type flagellum organization
CAH07_12285	COG1157	protein secretion by the type III secretion system
CAH07_12290	COG1317	bacterial-type flagellum organization
CAH07_12295	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAH07_12300	COG1766	The M ring may be actively involved in energy transduction
CAH07_12305	COG1677	Flagellar hook-basal body complex protein FliE
CAH07_12310	COG1558	bacterial-type flagellum-dependent cell motility
CAH07_12315	COG1815	bacterial-type flagellum-dependent cell motility
CAH07_12320	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CAH07_12325	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CAH07_12330	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CAH07_12335	COG4974	Belongs to the 'phage' integrase family
CAH07_12340	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CAH07_12345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAH07_12350	COG0758	DNA mediated transformation
CAH07_12355	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CAH07_12360	COG0045	succinate-CoA ligase (ADP-forming) activity
CAH07_12365	COG2257	FlhB HrpN YscU SpaS Family
CAH07_12375	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CAH07_12380	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CAH07_12385	COG0335	large ribosomal subunit rRNA binding
CAH07_12390	COG0336	Belongs to the RNA methyltransferase TrmD family
CAH07_12395	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CAH07_12405	COG1837	Belongs to the UPF0109 family
CAH07_12410	COG0228	four-way junction DNA binding
CAH07_12415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CAH07_12420	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CAH07_12430	COG0552	protein localization to endoplasmic reticulum
CAH07_12435	COG1196	nuclear chromosome segregation
CAH07_12440	COG0571	ribonuclease III activity
CAH07_12445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAH07_12450	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_12455	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CAH07_12460	COG0416	fatty acid biosynthetic process
CAH07_12465	COG2050	protein possibly involved in aromatic compounds catabolism
CAH07_12465	COG1349	DNA-binding transcription factor activity
CAH07_12470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CAH07_12475	COG1760	l-serine dehydratase
CAH07_12480	COG1760	l-serine dehydratase
CAH07_12485	COG1461	Dihydroxyacetone kinase
CAH07_12490	COG1302	Protein conserved in bacteria
CAH07_12495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CAH07_12505	COG1564	THIamine pyrophosphokinase
CAH07_12510	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CAH07_12515	COG1162	GTPase activity
CAH07_12520	COG2815	serine threonine protein kinase
CAH07_12520	COG0515	serine threonine protein kinase
CAH07_12525	COG0631	protein serine/threonine phosphatase activity
CAH07_12530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CAH07_12535	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CAH07_12535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAH07_12540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CAH07_12545	COG0242	peptide deformylase activity
CAH07_12550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CAH07_12555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CAH07_12560	COG1758	RNA polymerase activity
CAH07_12565	COG0194	GDP metabolic process
CAH07_12570	COG2052	Domain of unknown function (DUF370)
CAH07_12575	COG1561	YicC-like family, N-terminal region
CAH07_12580	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CAH07_12590	COG1648	precorrin-2 dehydrogenase activity
CAH07_12595	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CAH07_12600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAH07_12605	COG0529	Catalyzes the synthesis of activated sulfate
CAH07_12610	COG2046	Belongs to the sulfate adenylyltransferase family
CAH07_12615	COG0306	phosphate transporter
CAH07_12620	COG0175	sulfate reduction
CAH07_12625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CAH07_12630	COG0284	orotidine-5'-phosphate decarboxylase activity
CAH07_12635	COG0167	dihydroorotate dehydrogenase activity
CAH07_12640	COG0543	2 iron, 2 sulfur cluster binding
CAH07_12645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CAH07_12650	COG0505	Belongs to the CarA family
CAH07_12655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CAH07_12660	COG0540	Belongs to the ATCase OTCase family
CAH07_12665	COG2233	PERMEase
CAH07_12670	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CAH07_12675	COG0564	pseudouridine synthase activity
CAH07_12680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CAH07_12685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CAH07_12690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CAH07_12695	COG3599	regulation of cell shape
CAH07_12700	COG2302	S4 RNA-binding domain
CAH07_12705	COG0762	integral membrane protein
CAH07_12710	COG1799	cell septum assembly
CAH07_12715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CAH07_12725	COG1873	PFAM PRC-barrel domain
CAH07_12730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAH07_12735	COG1119	ATPase activity
CAH07_12740	COG1191	sigma factor activity
CAH07_12745	COG1191	sigma factor activity
CAH07_12755	COG4412	M6 family metalloprotease domain protein
CAH07_12755	COG1404	Belongs to the peptidase S8 family
CAH07_12760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CAH07_12765	COG0849	cell division
CAH07_12770	COG3856	small basic protein
CAH07_12775	COG3879	Bacterial protein of unknown function (DUF881)
CAH07_12780	COG3879	Bacterial protein of unknown function (DUF881)
CAH07_12785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CAH07_12790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CAH07_12795	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CAH07_12800	COG0772	Belongs to the SEDS family
CAH07_12805	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CAH07_12810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAH07_12815	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAH07_12820	COG0768	penicillin binding
CAH07_12830	COG4839	cell division protein FtsL
CAH07_12835	COG0275	rRNA processing
CAH07_12840	COG2001	Belongs to the MraZ family
CAH07_12845	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CAH07_12850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CAH07_12855	COG0454	-acetyltransferase
CAH07_12865	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CAH07_12870	COG1399	metal-binding, possibly nucleic acid-binding protein
CAH07_12880	COG1323	Belongs to the UPF0348 family
CAH07_12885	COG3480	Lon protease (S16) C-terminal proteolytic domain
CAH07_12890	COG1752	Esterase of the alpha-beta hydrolase superfamily
CAH07_12895	COG3314	Sporulation integral membrane protein YlbJ
CAH07_12900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CAH07_12905	COG0742	ribosomal rna small subunit methyltransferase
CAH07_12910	COG4471	UPF0298 protein
CAH07_12915	COG3679	Belongs to the UPF0342 family
CAH07_12930	COG2340	Cysteine-rich secretory protein family
CAH07_12935	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CAH07_12945	COG3336	cytochrome c oxidase
CAH07_12950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CAH07_12955	COG1845	cytochrome c oxidase, subunit III
CAH07_12960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAH07_12965	COG2010	Cytochrome c
CAH07_12965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CAH07_12970	COG0109	protoheme IX farnesyltransferase activity
CAH07_12975	COG1612	heme a metabolic process
CAH07_12980	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CAH07_12985	COG0772	Belongs to the SEDS family
CAH07_12990	COG4838	Belongs to the UPF0358 family
CAH07_12995	COG2066	Belongs to the glutaminase family
CAH07_13000	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CAH07_13005	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CAH07_13015	COG4896	Protein conserved in bacteria
CAH07_13045	COG1595	DNA-templated transcription, initiation
CAH07_13065	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CAH07_13075	COG0483	inositol monophosphate 1-phosphatase activity
CAH07_13085	COG4493	Belongs to the UPF0637 family
CAH07_13090	COG4476	Belongs to the UPF0223 family
CAH07_13095	COG1982	Orn Lys Arg decarboxylase major
CAH07_13105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAH07_13110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAH07_13115	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAH07_13120	COG0022	dehydrogenase e1 component
CAH07_13125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CAH07_13130	COG0497	DNA recombination
CAH07_13140	COG0242	peptide deformylase activity
CAH07_13145	COG0561	phosphatase activity
CAH07_13155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CAH07_13160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CAH07_13165	COG0569	domain protein
CAH07_13170	COG2105	PFAM AIG2 family protein
CAH07_13170	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CAH07_13175	COG3852	Histidine kinase
CAH07_13180	COG2002	toxin-antitoxin pair type II binding
CAH07_13185	COG1077	Cell shape determining protein MreB Mrl
CAH07_13195	COG2309	aminopeptidase activity
CAH07_13200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CAH07_13205	COG0488	(ABC) transporter
CAH07_13215	COG0681	Belongs to the peptidase S26 family
CAH07_13220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAH07_13220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAH07_13220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAH07_13225	COG1105	Belongs to the carbohydrate kinase PfkB family
CAH07_13230	COG1349	DNA-binding transcription factor activity
CAH07_13235	COG0577	efflux transmembrane transporter activity
CAH07_13240	COG1136	(ABC) transporter
CAH07_13245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAH07_13255	COG1132	(ABC) transporter
CAH07_13260	COG1132	(ABC) transporter
CAH07_13265	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CAH07_13270	COG0314	molybdopterin synthase activity
CAH07_13275	COG1763	Mo-molybdopterin cofactor biosynthetic process
CAH07_13280	COG0303	'Molybdopterin
CAH07_13285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CAH07_13290	COG0746	molybdenum cofactor guanylyltransferase activity
CAH07_13305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAH07_13310	COG0450	alkyl hydroperoxide reductase
CAH07_13315	COG0668	transmembrane transport
CAH07_13325	COG1473	amidohydrolase
CAH07_13330	COG2171	N-acyltransferase activity
CAH07_13335	COG0716	FMN binding
CAH07_13345	COG0716	FMN binding
CAH07_13350	COG0583	DNA-binding transcription factor activity
CAH07_13355	COG0517	IMP dehydrogenase activity
CAH07_13365	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CAH07_13370	COG4703	Protein of unknown function (DUF1797)
CAH07_13375	COG2200	EAL domain
CAH07_13380	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_13385	COG1408	metallophosphoesterase
CAH07_13390	COG1376	ErfK ybiS ycfS ynhG family protein
CAH07_13395	COG2814	Major facilitator Superfamily
CAH07_13405	COG0835	chemotaxis
CAH07_13405	COG0784	Response regulator, receiver
CAH07_13415	COG0436	Aminotransferase
CAH07_13420	COG4191	Histidine kinase
CAH07_13425	COG0768	penicillin binding
CAH07_13430	COG2340	Cysteine-rich secretory protein family
CAH07_13435	COG2084	Dehydrogenase
CAH07_13440	COG0840	transmembrane signaling receptor activity
CAH07_13445	COG0456	acetyltransferase
CAH07_13450	COG1533	DNA photolyase activity
CAH07_13460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CAH07_13465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAH07_13470	COG2190	(PTS) system
CAH07_13470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAH07_13470	COG1263	PTS System
CAH07_13475	COG3711	transcriptional antiterminator
CAH07_13480	COG1609	Transcriptional regulator
CAH07_13485	COG0006	proline dipeptidase activity
CAH07_13495	COG2217	Heavy metal translocating P-type atpase
CAH07_13500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAH07_13505	COG2244	polysaccharide biosynthetic process
CAH07_13510	COG3773	Cell wall hydrolase
CAH07_13520	COG4873	Protein conserved in bacteria
CAH07_13530	COG3858	chitin binding
CAH07_13535	COG1388	LysM domain
CAH07_13540	COG1388	LysM domain
CAH07_13540	COG4641	Protein conserved in bacteria
CAH07_13545	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_13550	COG1733	regulation of RNA biosynthetic process
CAH07_13555	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CAH07_13560	COG0602	queuosine metabolic process
CAH07_13565	COG0720	synthase
CAH07_13570	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CAH07_13575	COG3949	Membrane
CAH07_13580	COG0542	response to heat
CAH07_13590	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CAH07_13595	COG1360	Flagellar Motor Protein
CAH07_13600	COG1846	Transcriptional regulator
CAH07_13605	COG3852	Histidine kinase
CAH07_13620	COG3339	Conserved Protein
CAH07_13625	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CAH07_13630	COG0235	Class ii aldolase
CAH07_13635	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CAH07_13640	COG1850	ribulose-bisphosphate carboxylase activity
CAH07_13645	COG0436	Aminotransferase
CAH07_13650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CAH07_13655	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CAH07_13660	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CAH07_13665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CAH07_13670	COG5002	protein histidine kinase activity
CAH07_13675	COG3594	Acyltransferase
CAH07_13690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CAH07_13695	COG0501	Belongs to the peptidase M48B family
CAH07_13715	COG1191	sigma factor activity
CAH07_13720	COG0861	Integral membrane protein TerC family
CAH07_13725	COG0586	Pfam SNARE associated Golgi protein
CAH07_13730	COG5001	Diguanylate cyclase
CAH07_13730	COG3300	MHYT domain
CAH07_13735	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CAH07_13740	COG3285	dna ligase
CAH07_13740	COG1793	dna ligase
CAH07_13745	COG0463	Glycosyl transferase, family 2
CAH07_13755	COG1408	metallophosphoesterase
CAH07_13760	COG0726	polysaccharide deacetylase
CAH07_13765	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CAH07_13770	COG1846	Transcriptional regulator
CAH07_13785	COG0789	Transcriptional regulator
CAH07_13790	COG2239	Acts as a magnesium transporter
CAH07_13805	COG3212	peptidase
CAH07_13810	COG3212	peptidase
CAH07_13815	COG3850	Histidine kinase
CAH07_13815	COG5002	protein histidine kinase activity
CAH07_13820	COG0745	RESPONSE REGULATOR receiver
CAH07_13830	COG4721	ABC-type cobalt transport system, permease component
CAH07_13835	COG1122	ATPase activity
CAH07_13840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CAH07_13845	COG1366	Belongs to the anti-sigma-factor antagonist family
CAH07_13850	COG1404	Belongs to the peptidase S8 family
CAH07_13855	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CAH07_13860	COG0590	tRNA wobble adenosine to inosine editing
CAH07_13870	COG1764	response to oxidative stress
CAH07_13875	COG1846	Transcriptional regulator
CAH07_13880	COG1764	response to oxidative stress
CAH07_13885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CAH07_13890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CAH07_13895	COG0788	formyltetrahydrofolate deformylase activity
CAH07_13900	COG2076	Multidrug Resistance protein
CAH07_13905	COG2076	Multidrug Resistance protein
CAH07_13910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAH07_13915	COG2318	DinB family
CAH07_13920	COG2323	membrane
CAH07_13930	COG1017	nitric oxide dioxygenase activity
CAH07_13930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAH07_13935	COG1607	acyl-coa hydrolase
CAH07_13940	COG1834	amidinotransferase
CAH07_13945	COG2706	6-phosphogluconolactonase activity
CAH07_13950	COG4608	Belongs to the ABC transporter superfamily
CAH07_13955	COG0791	NLP P60 protein
CAH07_13960	COG4948	Mandelate Racemase Muconate Lactonizing
CAH07_13965	COG1619	proteins homologs of microcin C7 resistance protein MccF
CAH07_13970	COG4166	transmembrane transport
CAH07_13975	COG0444	Belongs to the ABC transporter superfamily
CAH07_13980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAH07_13985	COG0601	transmembrane transport
CAH07_13990	COG2362	D-Aminopeptidase
CAH07_13995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CAH07_14000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAH07_14005	COG0463	Glycosyl transferase, family 2
CAH07_14010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CAH07_14015	COG0346	lactoylglutathione lyase activity
CAH07_14020	COG0531	amino acid
CAH07_14025	COG1392	Phosphate transport regulator
CAH07_14030	COG0306	phosphate transporter
CAH07_14045	COG5632	N-Acetylmuramoyl-L-alanine amidase
CAH07_14045	COG3409	Peptidoglycan-binding domain 1 protein
CAH07_14085	COG3778	Protein conserved in bacteria
CAH07_14090	COG3299	homolog of phage Mu protein gp47
CAH07_14095	COG3628	GPW Gp25 family protein
CAH07_14105	COG4193	domain, Protein
CAH07_14110	COG1652	LysM domain
CAH07_14115	COG3953	SLT domain
CAH07_14115	COG5412	phage tail tape measure protein
CAH07_14165	COG4653	Phage capsid family
CAH07_14170	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CAH07_14175	COG5518	Phage portal protein
CAH07_14180	COG1783	phage Terminase large subunit
CAH07_14185	COG3728	DNA packaging
CAH07_14185	COG5484	DNA packaging
CAH07_14190	COG1595	DNA-templated transcription, initiation
CAH07_14210	COG1484	DNA-dependent DNA replication
CAH07_14215	COG1522	sequence-specific DNA binding
CAH07_14225	COG1396	sequence-specific DNA binding
CAH07_14230	COG2856	Zn peptidase
CAH07_14235	COG3546	catalase activity
CAH07_14240	COG4195	phage-related replication protein
CAH07_14250	COG1388	LysM domain
CAH07_14250	COG5632	N-Acetylmuramoyl-L-alanine amidase
CAH07_14250	COG3409	Peptidoglycan-binding domain 1 protein
CAH07_14255	COG2350	Protein conserved in bacteria
CAH07_14265	COG0457	Tetratricopeptide repeat
CAH07_14270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAH07_14275	COG2318	DinB family
CAH07_14280	COG0730	response to heat
CAH07_14285	COG2721	sulfolactate sulfo-lyase activity
CAH07_14290	COG0246	Mannitol dehydrogenase
CAH07_14295	COG1609	Transcriptional regulator
CAH07_14300	COG2271	Major facilitator Superfamily
CAH07_14305	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_14310	COG1312	Catalyzes the dehydration of D-mannonate
CAH07_14315	COG1063	alcohol dehydrogenase
CAH07_14320	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CAH07_14325	COG2211	Major facilitator Superfamily
CAH07_14330	COG1904	glucuronate isomerase
CAH07_14335	COG1252	NADH dehydrogenase
CAH07_14345	COG4297	protein containing double-stranded beta helix domain
CAH07_14350	COG0697	spore germination
CAH07_14355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CAH07_14360	COG0390	transport system, permease component
CAH07_14365	COG1587	Uroporphyrinogen-III synthase
CAH07_14375	COG1819	glycosyl
CAH07_14380	COG2124	cytochrome p450
CAH07_14390	COG1051	belongs to the nudix hydrolase family
CAH07_14400	COG2427	Protein of unknown function (DUF1641)
CAH07_14405	COG3383	formate dehydrogenase (NAD+) activity
CAH07_14415	COG2205	protein histidine kinase activity
CAH07_14420	COG5504	Zn-dependent protease
CAH07_14435	COG0726	polysaccharide deacetylase
CAH07_14445	COG0109	protoheme IX farnesyltransferase activity
CAH07_14465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CAH07_14475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAH07_14485	COG1482	cell wall glycoprotein biosynthetic process
CAH07_14490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAH07_14490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAH07_14490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAH07_14495	COG3711	transcriptional antiterminator
CAH07_14495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAH07_14505	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_14510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CAH07_14535	COG5444	nuclease activity
CAH07_14590	COG3409	Peptidoglycan-binding domain 1 protein
CAH07_14590	COG5632	N-Acetylmuramoyl-L-alanine amidase
CAH07_14705	COG5484	DNA packaging
CAH07_14720	COG3677	Transposase
CAH07_14790	COG1484	DNA-dependent DNA replication
CAH07_14795	COG3935	DnaD domain protein
CAH07_14840	COG3646	Phage regulatory protein
CAH07_14840	COG3645	SOS response
CAH07_14855	COG1396	sequence-specific DNA binding
CAH07_14865	COG2856	Zn peptidase
CAH07_14870	COG4974	Belongs to the 'phage' integrase family
CAH07_14880	COG5505	Protein of unknown function (DUF819)
CAH07_14885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAH07_14890	COG0626	cystathionine gamma-synthase activity
CAH07_14895	COG0626	cystathionine gamma-synthase activity
CAH07_14900	COG2382	esterase
CAH07_14905	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CAH07_14910	COG2153	protein acetylation
CAH07_14920	COG0210	DNA helicase
CAH07_14975	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CAH07_14980	COG0351	phosphomethylpyrimidine kinase
CAH07_14985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CAH07_14990	COG2022	thiamine diphosphate biosynthetic process
CAH07_14995	COG2104	thiamine diphosphate biosynthetic process
CAH07_15000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAH07_15005	COG0352	thiamine-phosphate diphosphorylase activity
CAH07_15010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CAH07_15015	COG0569	domain protein
CAH07_15015	COG0475	glutathione-regulated potassium exporter activity
CAH07_15020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CAH07_15025	COG0564	pseudouridine synthase activity
CAH07_15030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CAH07_15035	COG2357	RelA SpoT domain protein
CAH07_15045	COG4116	CYTH
CAH07_15050	COG0741	lytic transglycosylase activity
CAH07_15055	COG2346	COG2346, Truncated hemoglobins
CAH07_15075	COG1164	Oligoendopeptidase f
CAH07_15080	COG4469	Competence protein
CAH07_15085	COG4862	establishment of competence for transformation
CAH07_15090	COG0861	Integral membrane protein TerC family
CAH07_15095	COG1393	Belongs to the ArsC family
CAH07_15100	COG0456	acetyltransferase
CAH07_15105	COG2814	Major facilitator Superfamily
CAH07_15110	COG4608	Belongs to the ABC transporter superfamily
CAH07_15115	COG0444	Belongs to the ABC transporter superfamily
CAH07_15120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAH07_15125	COG0601	transmembrane transport
CAH07_15130	COG4166	transmembrane transport
CAH07_15135	COG0180	Tryptophanyl-tRNA synthetase
CAH07_15145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAH07_15150	COG0601	transmembrane transport
CAH07_15160	COG4608	Belongs to the ABC transporter superfamily
CAH07_15165	COG0444	Belongs to the ABC transporter superfamily
CAH07_15170	COG5504	Zn-dependent protease
CAH07_15175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CAH07_15180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAH07_15195	COG1744	ABC transporter substrate-binding protein PnrA-like
CAH07_15205	COG2267	carboxylic ester hydrolase activity
CAH07_15220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CAH07_15225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CAH07_15230	COG0505	Belongs to the CarA family
CAH07_15235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CAH07_15250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CAH07_15255	COG2271	Major facilitator Superfamily
CAH07_15260	COG0277	FAD linked oxidase domain protein
CAH07_15270	COG2151	metal-sulfur cluster biosynthetic enzyme
CAH07_15275	COG1073	alpha beta
CAH07_15280	COG0561	phosphatase activity
CAH07_15295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CAH07_15300	COG1307	EDD domain protein, DegV family
CAH07_15305	COG3227	Zinc metalloprotease (Elastase)
CAH07_15320	COG1695	Transcriptional regulator
CAH07_15340	COG2996	Protein conserved in bacteria
CAH07_15345	COG1666	GTP binding
CAH07_15350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CAH07_15350	COG0646	methionine synthase
CAH07_15355	COG2153	protein acetylation
CAH07_15360	COG0454	-acetyltransferase
CAH07_15365	COG2814	Major facilitator Superfamily
CAH07_15370	COG4948	Mandelate Racemase Muconate Lactonizing
CAH07_15375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CAH07_15380	COG1809	phosphosulfolactate synthase activity
CAH07_15385	COG2045	Belongs to the ComB family
CAH07_15390	COG0175	sulfate reduction
CAH07_15395	COG2046	Belongs to the sulfate adenylyltransferase family
CAH07_15400	COG0529	Catalyzes the synthesis of activated sulfate
CAH07_15405	COG2267	carboxylic ester hydrolase activity
CAH07_15410	COG1357	PFAM Pentapeptide repeats (8 copies)
CAH07_15415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAH07_15420	COG1279	arginine transmembrane transporter activity
CAH07_15425	COG2318	DinB family
CAH07_15430	COG0673	inositol 2-dehydrogenase activity
CAH07_15435	COG1609	Transcriptional regulator
CAH07_15440	COG1917	Cupin 2, conserved barrel domain protein
CAH07_15440	COG2207	Transcriptional regulator
CAH07_15445	COG0534	Mate efflux family protein
CAH07_15450	COG1562	ergosterol biosynthetic process
CAH07_15455	COG2318	DinB family
CAH07_15460	COG0367	asparagine synthase
CAH07_15470	COG1404	Belongs to the peptidase S8 family
CAH07_15480	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAH07_15485	COG5337	Spore coat protein CotH
CAH07_15525	COG1403	HNH endonuclease
CAH07_15530	COG0419	ATPase involved in DNA repair
CAH07_15535	COG0420	3'-5' exonuclease activity
CAH07_15540	COG1074	ATP-dependent DNA helicase activity
CAH07_15545	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CAH07_15550	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CAH07_15560	COG4533	DNA binding
CAH07_15565	COG2814	Major facilitator Superfamily
CAH07_15565	COG0477	Major facilitator Superfamily
CAH07_15570	COG3180	Ammonia monooxygenase
CAH07_15575	COG1609	Transcriptional regulator
CAH07_15580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CAH07_15585	COG0561	phosphatase activity
CAH07_15590	COG0673	inositol 2-dehydrogenase activity
CAH07_15595	COG0738	Major facilitator superfamily
CAH07_15600	COG1846	Transcriptional regulator
CAH07_15605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAH07_15610	COG0681	Belongs to the peptidase S26 family
CAH07_15615	COG0398	Pfam SNARE associated Golgi protein
CAH07_15630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAH07_15640	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_15645	COG4903	ComK protein
CAH07_15655	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_15660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAH07_15660	COG0723	plastoquinol--plastocyanin reductase activity
CAH07_15665	COG0840	transmembrane signaling receptor activity
CAH07_15670	COG1268	BioY protein
CAH07_15675	COG0318	PFAM AMP-dependent synthetase and ligase
CAH07_15680	COG0183	Belongs to the thiolase family
CAH07_15685	COG0406	alpha-ribazole phosphatase activity
CAH07_15690	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CAH07_15695	COG0604	alcohol dehydrogenase
CAH07_15700	COG0456	acetyltransferase
CAH07_15710	COG0501	Belongs to the peptidase M48B family
CAH07_15720	COG0318	PFAM AMP-dependent synthetase and ligase
CAH07_15725	COG0702	epimerase
CAH07_15730	COG0095	Lipoate-protein ligase
CAH07_15735	COG1234	tRNA 3'-trailer cleavage
CAH07_15745	COG1301	dicarboxylic acid transport
CAH07_15750	COG4405	Protein conserved in bacteria
CAH07_15755	COG1363	Peptidase, m42
CAH07_15765	COG4377	Putative membrane peptidase family (DUF2324)
CAH07_15770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAH07_15775	COG1511	domain protein
CAH07_15780	COG1309	transcriptional regulator
CAH07_15795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CAH07_15800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAH07_15805	COG2329	Antibiotic biosynthesis monooxygenase
CAH07_15815	COG3069	C4-dicarboxylate transmembrane transporter activity
CAH07_15820	COG1473	amidohydrolase
CAH07_15830	COG4473	ABC transporter
CAH07_15835	COG1131	(ABC) transporter
CAH07_15840	COG0537	adenosine 5'-monophosphoramidase activity
CAH07_15845	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CAH07_15860	COG4980	gas vesicle protein
CAH07_15865	COG1846	Transcriptional regulator
CAH07_15895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAH07_15905	COG3481	metal-dependent phosphohydrolase, HD sub domain
CAH07_15910	COG4717	serine-type aminopeptidase activity
CAH07_15915	COG0420	3'-5' exonuclease activity
CAH07_15920	COG1668	transmembrane transport
CAH07_15925	COG4152	abc transporter atp-binding protein
CAH07_15935	COG1024	Enoyl-CoA hydratase
CAH07_15945	COG0490	domain, Protein
CAH07_15950	COG0475	glutathione-regulated potassium exporter activity
CAH07_15955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CAH07_15960	COG0561	phosphatase activity
CAH07_15965	COG4335	DNA alkylation repair
CAH07_15970	COG3679	Belongs to the UPF0342 family
CAH07_15975	COG4399	Belongs to the UPF0754 family
CAH07_15980	COG0189	ligase activity
CAH07_15985	COG0189	ligase activity
CAH07_16005	COG0702	epimerase
CAH07_16010	COG1132	(ABC) transporter
CAH07_16015	COG1132	(ABC) transporter
CAH07_16025	COG0589	response to stress
CAH07_16030	COG1757	Na H antiporter
CAH07_16035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CAH07_16040	COG0726	polysaccharide deacetylase
CAH07_16045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CAH07_16050	COG0668	transmembrane transport
CAH07_16060	COG0584	glycerophosphoryl diester phosphodiesterase
CAH07_16065	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CAH07_16070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CAH07_16075	COG1253	flavin adenine dinucleotide binding
CAH07_16080	COG0436	Aminotransferase
CAH07_16085	COG0789	Transcriptional regulator
CAH07_16090	COG1253	flavin adenine dinucleotide binding
CAH07_16095	COG0204	Acyl-transferase
CAH07_16100	COG0667	Aldo Keto reductase
CAH07_16105	COG1595	DNA-templated transcription, initiation
CAH07_16120	COG0456	acetyltransferase
CAH07_16125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAH07_16130	COG0733	neurotransmitter:sodium symporter activity
CAH07_16135	COG0531	amino acid
CAH07_16140	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_16145	COG0372	Belongs to the citrate synthase family
CAH07_16150	COG0583	DNA-binding transcription factor activity
CAH07_16155	COG1388	LysM domain
CAH07_16155	COG0791	NLP P60 protein
CAH07_16160	COG1785	Belongs to the alkaline phosphatase family
CAH07_16165	COG2719	SpoVR family
CAH07_16170	COG0668	transmembrane transport
CAH07_16175	COG1959	2 iron, 2 sulfur cluster binding
CAH07_16180	COG1388	LysM domain
CAH07_16180	COG0791	NLP P60 protein
CAH07_16195	COG0431	NADPH-dependent FMN reductase
CAH07_16200	COG2197	response regulator
CAH07_16205	COG4585	Histidine kinase
CAH07_16205	COG2203	Gaf domain
CAH07_16210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CAH07_16215	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CAH07_16220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CAH07_16225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CAH07_16230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CAH07_16235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAH07_16240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CAH07_16240	COG3153	acetyltransferase
CAH07_16245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAH07_16250	COG0517	IMP dehydrogenase activity
CAH07_16260	COG0564	pseudouridine synthase activity
CAH07_16265	COG3764	Sortase (surface protein transpeptidase)
CAH07_16270	COG0737	Belongs to the 5'-nucleotidase family
CAH07_16270	COG4085	toxin activity
CAH07_16270	COG1525	nuclease
CAH07_16275	COG5577	PFAM Coat F domain
CAH07_16295	COG1823	symporter activity
CAH07_16300	COG3706	GGDEF domain
CAH07_16305	COG1464	Belongs to the NlpA lipoprotein family
CAH07_16315	COG1278	Cold shock
CAH07_16320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CAH07_16325	COG1131	(ABC) transporter
CAH07_16330	COG1131	(ABC) transporter
CAH07_16335	COG1725	Transcriptional regulator
CAH07_16355	COG0655	NAD(P)H dehydrogenase (quinone) activity
CAH07_16360	COG2814	Major facilitator Superfamily
CAH07_16365	COG1566	PFAM secretion protein HlyD family protein
CAH07_16370	COG1846	Transcriptional regulator
CAH07_16375	COG2718	Belongs to the UPF0229 family
CAH07_16380	COG2766	serine protein kinase
CAH07_16385	COG1664	Polymer-forming cytoskeletal
CAH07_16390	COG1664	Polymer-forming cytoskeletal
CAH07_16395	COG0789	Transcriptional regulator
CAH07_16400	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CAH07_16410	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CAH07_16415	COG3382	B3 4 domain protein
CAH07_16425	COG1476	TRANSCRIPTIONal
CAH07_16435	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CAH07_16445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAH07_16450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAH07_16455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAH07_16460	COG1116	anion transmembrane transporter activity
CAH07_16465	COG0753	catalase activity
CAH07_16475	COG0277	FAD linked oxidase domain protein
CAH07_16480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CAH07_16485	COG3340	Belongs to the peptidase S51 family
CAH07_16490	COG5577	PFAM Coat F domain
CAH07_16500	COG4326	sporulation control protein
CAH07_16610	COG0735	belongs to the Fur family
CAH07_16615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CAH07_16620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CAH07_16625	COG4129	membrane
CAH07_16630	COG1132	(ABC) transporter
CAH07_16635	COG3557	Belongs to the UPF0374 family
CAH07_16650	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_16660	COG1194	a g-specific adenine glycosylase
CAH07_16665	COG1988	membrane-bound metal-dependent
CAH07_16670	COG4485	Bacterial membrane protein, YfhO
CAH07_16675	COG0463	Glycosyl transferase, family 2
CAH07_16680	COG0596	Alpha beta hydrolase
CAH07_16685	COG5658	integral membrane protein
CAH07_16690	COG3103	Sh3 type 3 domain protein
CAH07_16705	COG2814	Major facilitator Superfamily
CAH07_16715	COG2137	regulation of response to DNA damage stimulus
CAH07_16720	COG1090	epimerase
CAH07_16735	COG0778	Nitroreductase
CAH07_16740	COG0384	phenazine biosynthesis protein PhzF
CAH07_16745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAH07_16750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAH07_16755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CAH07_16760	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CAH07_16760	COG0392	lysyltransferase activity
CAH07_16765	COG1846	Transcriptional regulator
CAH07_16770	COG2814	Major facilitator Superfamily
CAH07_16775	COG2318	DinB family
CAH07_16780	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CAH07_16785	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CAH07_16790	COG1695	Transcriptional regulator
CAH07_16795	COG0842	Transport permease protein
CAH07_16800	COG0842	Transport permease protein
CAH07_16800	COG1511	domain protein
CAH07_16805	COG1131	(ABC) transporter
CAH07_16810	COG2197	response regulator
CAH07_16815	COG4585	Histidine kinase
CAH07_16820	COG2514	catechol 2,3-dioxygenase activity
CAH07_16825	COG2259	Doxx family
CAH07_16830	COG1132	(ABC) transporter
CAH07_16835	COG1132	(ABC) transporter
CAH07_16840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAH07_16840	COG1263	PTS System
CAH07_16845	COG1737	Transcriptional regulator
CAH07_16850	COG1486	melibiose metabolic process
CAH07_16855	COG4842	Belongs to the WXG100 family
CAH07_16880	COG1742	UPF0060 membrane protein
CAH07_16890	COG3284	Transcriptional regulator
CAH07_16895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAH07_16900	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAH07_16905	COG0022	dehydrogenase e1 component
CAH07_16910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CAH07_16920	COG4637	Psort location Cytoplasmic, score
CAH07_16925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CAH07_16935	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CAH07_16940	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CAH07_16945	COG0598	Magnesium transport protein CorA
CAH07_16950	COG2084	Dehydrogenase
CAH07_16955	COG0726	polysaccharide deacetylase
CAH07_16965	COG0535	radical SAM domain protein
CAH07_16970	COG0668	transmembrane transport
CAH07_16980	COG0387	Pfam Sodium calcium exchanger
CAH07_16985	COG0477	Major facilitator Superfamily
CAH07_16990	COG1295	ribonuclease BN
CAH07_16995	COG4980	gas vesicle protein
CAH07_17000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CAH07_17005	COG4840	Belongs to the UPF0435 family
CAH07_17010	COG2814	Major facilitator Superfamily
CAH07_17015	COG0693	protein deglycase activity
CAH07_17020	COG0737	Belongs to the 5'-nucleotidase family
CAH07_17025	COG0778	Nitroreductase
CAH07_17030	COG2188	Transcriptional regulator
CAH07_17035	COG0366	Alpha amylase catalytic
CAH07_17040	COG1263	PTS System
CAH07_17040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAH07_17045	COG0697	spore germination
CAH07_17060	COG0531	amino acid
CAH07_17065	COG1115	amino acid carrier protein
CAH07_17080	COG1368	sulfuric ester hydrolase activity
CAH07_17085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAH07_17085	COG1263	PTS System
CAH07_17090	COG0024	Methionine aminopeptidase
CAH07_17110	COG2258	MOSC domain
CAH07_17115	COG1254	Belongs to the acylphosphatase family
CAH07_17120	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CAH07_17125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAH07_17130	COG2851	Citrate transporter
CAH07_17135	COG3181	Tripartite tricarboxylate transporter family receptor
CAH07_17140	COG4565	transcriptional regulatory protein
CAH07_17145	COG3290	protein histidine kinase activity
CAH07_17150	COG0471	metal ion transport
CAH07_17155	COG3866	Pectate lyase
CAH07_17175	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CAH07_17180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAH07_17185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAH07_17190	COG1120	ATPase activity
CAH07_17195	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CAH07_17200	COG2211	Major facilitator Superfamily
CAH07_17210	COG2130	NADP-dependent
CAH07_17215	COG0456	acetyltransferase
CAH07_17220	COG0513	Belongs to the DEAD box helicase family
CAH07_17225	COG0488	(ABC) transporter
CAH07_17240	COG2814	Major facilitator Superfamily
CAH07_17245	COG0789	Transcriptional regulator
CAH07_17255	COG0488	(ABC) transporter
CAH07_17260	COG0840	transmembrane signaling receptor activity
CAH07_17265	COG1012	belongs to the aldehyde dehydrogenase family
CAH07_17270	COG0531	amino acid
CAH07_17280	COG2223	nitrite transmembrane transporter activity
CAH07_17285	COG1442	glycosyl transferase family 8
CAH07_17290	COG1216	Glycosyl transferase, family 2
CAH07_17295	COG1442	glycosyl transferase family 8
CAH07_17300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAH07_17305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CAH07_17310	COG1368	sulfuric ester hydrolase activity
CAH07_17315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CAH07_17315	COG2124	cytochrome p450
CAH07_17340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAH07_17345	COG0670	Belongs to the BI1 family
CAH07_17350	COG5583	Uncharacterized small protein (DUF2292)
CAH07_17365	COG0346	lactoylglutathione lyase activity
CAH07_17370	COG2329	Antibiotic biosynthesis monooxygenase
CAH07_17375	COG2323	membrane
CAH07_17380	COG1486	melibiose metabolic process
CAH07_17385	COG0395	ABC-type sugar transport system, permease component
CAH07_17390	COG4209	transmembrane transport
CAH07_17395	COG1653	transport
CAH07_17405	COG1874	Beta-galactosidase
CAH07_17410	COG2755	lipolytic protein G-D-S-L family
CAH07_17415	COG3401	FG-GAP repeat protein
CAH07_17420	COG3401	FG-GAP repeat protein
CAH07_17425	COG5578	integral membrane protein
CAH07_17435	COG2755	lipolytic protein G-D-S-L family
CAH07_17440	COG2207	Transcriptional regulator
CAH07_17445	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CAH07_17450	COG0395	ABC-type sugar transport system, permease component
CAH07_17455	COG1175	transmembrane transport
CAH07_17460	COG1653	transport
CAH07_17465	COG2207	Transcriptional regulator
CAH07_17465	COG4753	response regulator
CAH07_17470	COG2972	Histidine kinase
CAH07_17475	COG5578	integral membrane protein
CAH07_17485	COG0454	-acetyltransferase
CAH07_17490	COG3546	catalase activity
CAH07_17510	COG3631	Ketosteroid isomerase-related protein
CAH07_17515	COG1309	transcriptional regulator
CAH07_17525	COG0217	transcriptional regulatory protein
CAH07_17535	COG0457	Tetratricopeptide repeat
CAH07_17545	COG3391	amine dehydrogenase activity
CAH07_17550	COG5444	nuclease activity
CAH07_17565	COG0457	Tetratricopeptide repeat
CAH07_17585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CAH07_17595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CAH07_17600	COG1597	lipid kinase activity
CAH07_17605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAH07_17615	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CAH07_17620	COG0154	amidase activity
CAH07_17625	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CAH07_17630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAH07_17635	COG1285	pathogenesis
CAH07_17640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CAH07_17645	COG4851	CamS sex pheromone cAM373 precursor
CAH07_17650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CAH07_17655	COG0210	DNA helicase
CAH07_17660	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CAH07_17665	COG0069	glutamate synthase activity
CAH07_17670	COG4496	protein, YerC YecD
CAH07_17675	COG1470	cell adhesion involved in biofilm formation
CAH07_17680	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CAH07_17690	COG0531	amino acid
CAH07_17695	COG1522	sequence-specific DNA binding
CAH07_17700	COG0151	Belongs to the GarS family
CAH07_17705	COG0138	bifunctional purine biosynthesis protein purh
CAH07_17710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CAH07_17715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CAH07_17720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CAH07_17725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CAH07_17730	COG0047	phosphoribosylformylglycinamidine synthase activity
CAH07_17735	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CAH07_17740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CAH07_17745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CAH07_17750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CAH07_17755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CAH07_17765	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CAH07_17775	COG3064	Membrane
CAH07_17780	COG2252	PERMEase
CAH07_17795	COG0519	Catalyzes the synthesis of GMP from XMP
CAH07_17795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CAH07_17800	COG1305	Transglutaminase-like
CAH07_17805	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CAH07_17810	COG0714	Associated with various cellular activities
CAH07_17815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CAH07_17825	COG1113	amino acid transport
CAH07_17830	COG2132	Multicopper oxidase
CAH07_17840	COG2267	carboxylic ester hydrolase activity
CAH07_17855	COG0823	Involved in the tonB-independent uptake of proteins
CAH07_17860	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CAH07_17865	COG1063	alcohol dehydrogenase
CAH07_17870	COG2814	Major facilitator Superfamily
CAH07_17880	COG4260	virion core protein, lumpy skin disease virus
CAH07_17885	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CAH07_17890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CAH07_17895	COG1842	Phage shock protein A
CAH07_17900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAH07_17905	COG2211	Major facilitator Superfamily
CAH07_17910	COG1063	alcohol dehydrogenase
CAH07_17915	COG0457	Tetratricopeptide repeat
CAH07_17920	COG1073	alpha beta
CAH07_17930	COG0459	protein refolding
CAH07_17935	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CAH07_17940	COG1266	CAAX protease self-immunity
CAH07_17955	COG0805	protein transport
CAH07_17960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAH07_17965	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CAH07_17970	COG0315	cyclic pyranopterin monophosphate synthase activity
CAH07_17975	COG0488	(ABC) transporter
CAH07_17980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CAH07_17985	COG0456	acetyltransferase
CAH07_17990	COG1214	PFAM Peptidase M22, glycoprotease
CAH07_17995	COG0802	atpase or kinase
CAH07_18000	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CAH07_18045	COG4124	Belongs to the glycosyl hydrolase 26 family
CAH07_18050	COG1482	cell wall glycoprotein biosynthetic process
CAH07_18055	COG1940	carbohydrate kinase activity
CAH07_18060	COG2188	Transcriptional regulator
CAH07_18065	COG2723	6-phospho-beta-galactosidase activity
CAH07_18070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CAH07_18075	COG1447	Phosphotransferase system cellobiose-specific component IIA
CAH07_18080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CAH07_18085	COG2814	Major facilitator Superfamily
CAH07_18090	COG1388	LysM domain
CAH07_18095	COG1078	dGTPase activity
CAH07_18100	COG0454	-acetyltransferase
CAH07_18110	COG5646	InterPro IPR014922
CAH07_18115	COG1785	Belongs to the alkaline phosphatase family
CAH07_18125	COG1819	glycosyl
CAH07_18130	COG3858	chitin binding
CAH07_18130	COG1388	LysM domain
CAH07_18135	COG1802	Transcriptional regulator
CAH07_18140	COG0730	response to heat
CAH07_18145	COG2814	Major facilitator Superfamily
CAH07_18150	COG1846	Transcriptional regulator
CAH07_18155	COG0778	Nitroreductase
CAH07_18160	COG2409	Drug exporters of the RND superfamily
CAH07_18160	COG1033	growth of symbiont in host cell
CAH07_18165	COG1846	Transcriptional regulator
CAH07_18170	COG2318	DinB family
CAH07_18175	COG1113	amino acid transport
CAH07_18185	COG0456	acetyltransferase
CAH07_18195	COG1309	transcriptional regulator
CAH07_18210	COG0071	Belongs to the small heat shock protein (HSP20) family
CAH07_18215	COG2323	membrane
CAH07_18220	COG2323	membrane
CAH07_18240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAH07_18245	COG2259	Doxx family
CAH07_18250	COG0346	lactoylglutathione lyase activity
CAH07_18255	COG0778	Nitroreductase
CAH07_18260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CAH07_18265	COG4978	Transcriptional regulator
CAH07_18265	COG0789	Transcriptional regulator
CAH07_18270	COG1811	Na channel or pump
CAH07_18275	COG0596	Alpha beta hydrolase
CAH07_18280	COG2409	Drug exporters of the RND superfamily
CAH07_18285	COG2197	response regulator
CAH07_18290	COG4585	Histidine kinase
CAH07_18305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAH07_18310	COG0640	Transcriptional regulator
CAH07_18315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAH07_18320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAH07_18325	COG0697	spore germination
CAH07_18330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAH07_18340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CAH07_18345	COG0640	Transcriptional regulator
CAH07_18350	COG1309	transcriptional regulator
CAH07_18355	COG2814	Major facilitator Superfamily
CAH07_18360	COG2249	NAD(P)H dehydrogenase (quinone) activity
CAH07_18365	COG1733	regulation of RNA biosynthetic process
CAH07_18370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CAH07_18375	COG1733	regulation of RNA biosynthetic process
CAH07_18380	COG3545	Serine hydrolase
CAH07_18385	COG2030	dehydratase
CAH07_18390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAH07_18395	COG0697	spore germination
CAH07_18400	COG1309	transcriptional regulator
CAH07_18405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAH07_18420	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CAH07_18430	COG0477	Major facilitator Superfamily
CAH07_18435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAH07_18440	COG2207	Transcriptional regulator
CAH07_18440	COG3708	Transcriptional regulator
CAH07_18445	COG0697	spore germination
CAH07_18450	COG2207	Transcriptional regulator
CAH07_18450	COG1917	Cupin 2, conserved barrel domain protein
CAH07_18455	COG0697	spore germination
CAH07_18465	COG1329	Transcriptional regulator
CAH07_18470	COG1278	Cold shock
CAH07_18475	COG3239	Fatty acid desaturase
CAH07_18485	COG1476	TRANSCRIPTIONal
CAH07_18500	COG1132	(ABC) transporter
CAH07_18505	COG0515	serine threonine protein kinase
CAH07_18515	COG0515	serine threonine protein kinase
CAH07_18565	COG3091	SprT-like family
CAH07_18575	COG2183	response to ionizing radiation
CAH07_18580	COG2208	phosphoserine phosphatase activity
CAH07_18585	COG1191	sigma factor activity
CAH07_18590	COG2172	sigma factor antagonist activity
CAH07_18595	COG1366	Belongs to the anti-sigma-factor antagonist family
CAH07_18600	COG2208	phosphoserine phosphatase activity
CAH07_18605	COG2172	sigma factor antagonist activity
CAH07_18610	COG1366	Belongs to the anti-sigma-factor antagonist family
CAH07_18615	COG1366	Belongs to the anti-sigma-factor antagonist family
CAH07_18620	COG2337	Toxic component of a toxin-antitoxin (TA) module
CAH07_18625	COG0864	Transcriptional regulator
CAH07_18630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CAH07_18635	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CAH07_18640	COG0736	holo-[acyl-carrier-protein] synthase activity
CAH07_18645	COG0705	Rhomboid family
CAH07_18650	COG3428	Bacterial PH domain
CAH07_18655	COG3402	PFAM membrane-flanked domain
CAH07_18660	COG0513	Belongs to the DEAD box helicase family
CAH07_18670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CAH07_18675	COG1181	Belongs to the D-alanine--D-alanine ligase family
CAH07_18680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAH07_18685	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CAH07_18700	COG1960	acyl-CoA dehydrogenase activity
CAH07_18710	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CAH07_18715	COG1131	(ABC) transporter
CAH07_18720	COG0628	permease
CAH07_18725	COG1301	dicarboxylic acid transport
CAH07_18730	COG4565	transcriptional regulatory protein
CAH07_18735	COG3290	protein histidine kinase activity
CAH07_18740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAH07_18745	COG3546	catalase activity
CAH07_18750	COG2329	Antibiotic biosynthesis monooxygenase
CAH07_18755	COG0662	Cupin 2, conserved barrel domain protein
CAH07_18760	COG3729	General stress protein
CAH07_18765	COG2217	Heavy metal translocating P-type atpase
CAH07_18770	COG4876	unkown
CAH07_18775	COG2261	transglycosylase associated protein
CAH07_18780	COG1914	H( )-stimulated, divalent metal cation uptake system
CAH07_18790	COG0028	Belongs to the TPP enzyme family
CAH07_18795	COG0494	nUDIX hydrolase
CAH07_18800	COG0531	amino acid
CAH07_18810	COG1215	transferase activity, transferring glycosyl groups
CAH07_18815	COG5298	Protein conserved in bacteria
CAH07_18820	COG3706	GGDEF domain
CAH07_18825	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CAH07_18830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAH07_18830	COG0551	DNA topoisomerase type I activity
CAH07_18835	COG1522	sequence-specific DNA binding
CAH07_18840	COG2814	Major facilitator Superfamily
CAH07_18850	COG3871	stress protein (general stress protein 26)
CAH07_18855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAH07_18860	COG1917	Cupin 2, conserved barrel domain protein
CAH07_18865	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_18870	COG2226	methyltransferase
CAH07_18875	COG0318	PFAM AMP-dependent synthetase and ligase
CAH07_18880	COG3711	transcriptional antiterminator
CAH07_18885	COG4989	oxidoreductase activity
CAH07_18890	COG0768	penicillin binding
CAH07_18895	COG2329	Antibiotic biosynthesis monooxygenase
CAH07_18905	COG2755	lipolytic protein G-D-S-L family
CAH07_18910	COG1414	Transcriptional regulator
CAH07_18915	COG1984	allophanate hydrolase subunit 2
CAH07_18920	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CAH07_18925	COG4336	lyase activity
CAH07_18930	COG1914	H( )-stimulated, divalent metal cation uptake system
CAH07_18935	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CAH07_18940	COG0561	phosphatase activity
CAH07_18950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CAH07_18955	COG0412	Dienelactone hydrolase
CAH07_18960	COG0681	Belongs to the peptidase S26 family
CAH07_18965	COG0473	3-isopropylmalate dehydrogenase activity
CAH07_18970	COG0246	Mannitol dehydrogenase
CAH07_18975	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAH07_18980	COG2213	PTS system mannitol-specific
CAH07_18990	COG1349	DNA-binding transcription factor activity
CAH07_18995	COG2372	response to copper ion
CAH07_18995	COG1276	copper resistance
CAH07_19000	COG4549	nuclear export factor GLE1
CAH07_19005	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_19010	COG4975	Glucose uptake
CAH07_19015	COG1012	belongs to the aldehyde dehydrogenase family
CAH07_19020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CAH07_19025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAH07_19030	COG0640	Transcriptional regulator
CAH07_19035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CAH07_19040	COG0778	Nitroreductase
CAH07_19045	COG1309	transcriptional regulator
CAH07_19050	COG2814	Major facilitator Superfamily
CAH07_19055	COG4607	ABC-type enterochelin transport system periplasmic component
CAH07_19060	COG4604	ABC transporter, ATP-binding protein
CAH07_19065	COG4605	iron ion homeostasis
CAH07_19070	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAH07_19075	COG0527	aspartate kinase activity
CAH07_19095	COG0457	Tetratricopeptide repeat
CAH07_19100	COG5002	protein histidine kinase activity
CAH07_19100	COG3850	Histidine kinase
CAH07_19105	COG0745	RESPONSE REGULATOR receiver
CAH07_19110	COG0577	efflux transmembrane transporter activity
CAH07_19115	COG1136	(ABC) transporter
CAH07_19120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CAH07_19130	COG0697	spore germination
CAH07_19140	COG5434	Belongs to the glycosyl hydrolase 28 family
CAH07_19145	COG3104	oligopeptide transport
CAH07_19150	COG0596	Alpha beta hydrolase
CAH07_19165	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CAH07_19170	COG0163	prenyltransferase activity
CAH07_19175	COG0583	DNA-binding transcription factor activity
CAH07_19180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAH07_19185	COG0765	amino acid transport
CAH07_19190	COG1126	abc transporter atp-binding protein
CAH07_19195	COG2364	Membrane
CAH07_19205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAH07_19210	COG0697	spore germination
CAH07_19220	COG2814	Major facilitator Superfamily
CAH07_19225	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CAH07_19230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_19235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_19240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAH07_19245	COG1733	regulation of RNA biosynthetic process
CAH07_19250	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CAH07_19255	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CAH07_19260	COG0840	transmembrane signaling receptor activity
CAH07_19260	COG3290	protein histidine kinase activity
CAH07_19265	COG3209	COG3209 Rhs family protein
CAH07_19275	COG2723	6-phospho-beta-galactosidase activity
CAH07_19285	COG1714	RDD family
CAH07_19290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAH07_19295	COG0765	amino acid transport
CAH07_19300	COG0523	cobalamin synthesis protein
CAH07_19310	COG1376	ErfK ybiS ycfS ynhG family protein
CAH07_19315	COG1469	GTP cyclohydrolase I activity
CAH07_19320	COG2223	nitrite transmembrane transporter activity
CAH07_19325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAH07_19330	COG0243	molybdopterin cofactor binding
CAH07_19335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAH07_19340	COG2146	nitrite reductase [NAD(P)H] activity
CAH07_19345	COG1587	Uroporphyrinogen-III synthase
CAH07_19345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAH07_19350	COG0492	ferredoxin-NADP+ reductase activity
CAH07_19355	COG2267	carboxylic ester hydrolase activity
CAH07_19360	COG0701	Predicted permease
CAH07_19365	COG3689	TIGRFAM TIGR03943 family protein
CAH07_19370	COG2508	Transcriptional regulator
CAH07_19375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAH07_19380	COG1012	belongs to the aldehyde dehydrogenase family
CAH07_19385	COG0506	proline dehydrogenase activity
CAH07_19390	COG3541	Predicted nucleotidyltransferase
CAH07_19395	COG3458	cephalosporin-C deacetylase activity
CAH07_19400	COG0583	DNA-binding transcription factor activity
CAH07_19405	COG2226	methyltransferase
CAH07_19410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CAH07_19415	COG1660	Displays ATPase and GTPase activities
CAH07_19420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CAH07_19425	COG3665	Urea carboxylase-associated protein
CAH07_19430	COG1113	amino acid transport
CAH07_19435	COG3403	YqcI/YcgG family
CAH07_19440	COG1280	lysine exporter protein (LysE YggA)
CAH07_19445	COG1846	Transcriptional regulator
CAH07_19450	COG2814	Major facilitator Superfamily
CAH07_19455	COG1620	l-lactate permease
CAH07_19460	COG0039	L-malate dehydrogenase activity
CAH07_19465	COG0366	Alpha amylase catalytic
CAH07_19475	COG1288	antiporter activity
CAH07_19480	COG1473	amidohydrolase
CAH07_19485	COG2113	Glycine betaine
CAH07_19490	COG4176	ABC-type proline glycine betaine transport system permease component
CAH07_19495	COG0517	IMP dehydrogenase activity
CAH07_19495	COG4175	Glycine betaine
CAH07_19500	COG0640	Transcriptional regulator
CAH07_19505	COG2814	Major facilitator Superfamily
CAH07_19515	COG0477	Major facilitator Superfamily
CAH07_19520	COG3853	Toxic anion resistance protein (TelA)
CAH07_19530	COG0861	Integral membrane protein TerC family
CAH07_19535	COG2310	stress, protein
CAH07_19540	COG2310	stress, protein
CAH07_19545	COG2310	stress, protein
CAH07_19550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAH07_19555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CAH07_19560	COG1121	(ABC) transporter
CAH07_19565	COG0803	Belongs to the bacterial solute-binding protein 9 family
CAH07_19570	COG0366	Alpha amylase catalytic
CAH07_19575	COG1028	Short-chain dehydrogenase reductase Sdr
CAH07_19580	COG0457	Tetratricopeptide repeat
CAH07_19585	COG1876	peptidase activity
CAH07_19590	COG1595	DNA-templated transcription, initiation
CAH07_19600	COG1595	DNA-templated transcription, initiation
CAH07_19615	COG1668	transmembrane transport
CAH07_19620	COG4555	ABC transporter
CAH07_19625	COG3279	Response regulator of the LytR AlgR family
CAH07_19630	COG3290	protein histidine kinase activity
CAH07_19635	COG1405	negative regulation of cell septum assembly
CAH07_19635	COG3012	SEC-C Motif Domain Protein
CAH07_19640	COG1714	RDD family
CAH07_19645	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CAH07_19650	COG0252	asparaginase activity
CAH07_19655	COG1309	transcriptional regulator
CAH07_19660	COG0477	Major facilitator Superfamily
CAH07_19665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CAH07_19670	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CAH07_19675	COG0805	protein transport
CAH07_19680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAH07_19685	COG3540	Alkaline phosphatase
CAH07_19695	COG2304	oxidoreductase activity
CAH07_19700	COG3773	Cell wall hydrolase
CAH07_19715	COG1131	(ABC) transporter
CAH07_19720	COG2205	protein histidine kinase activity
CAH07_19725	COG0745	RESPONSE REGULATOR receiver
CAH07_19740	COG3173	Aminoglycoside phosphotransferase
CAH07_19745	COG2721	sulfolactate sulfo-lyase activity
CAH07_19750	COG2186	Transcriptional regulator
CAH07_19755	COG4948	Mandelate Racemase Muconate Lactonizing
CAH07_19760	COG2271	Major facilitator Superfamily
CAH07_19765	COG1012	belongs to the aldehyde dehydrogenase family
CAH07_19770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAH07_19780	COG0784	Response regulator, receiver
CAH07_19785	COG4191	Histidine kinase
CAH07_19790	COG2066	Belongs to the glutaminase family
CAH07_19795	COG1115	amino acid carrier protein
CAH07_19805	COG2040	homocysteine
CAH07_19810	COG0833	amino acid
CAH07_19815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CAH07_19830	COG0363	glucosamine-6-phosphate deaminase activity
CAH07_19835	COG2190	(PTS) system
CAH07_19835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAH07_19835	COG1263	PTS System
CAH07_19840	COG1301	dicarboxylic acid transport
CAH07_19855	COG0688	phosphatidylethanolamine metabolic process
CAH07_19860	COG0586	Pfam SNARE associated Golgi protein
CAH07_19865	COG1183	phosphatidylcholine synthase activity
CAH07_19870	COG0596	Alpha beta hydrolase
CAH07_19880	COG3591	Belongs to the peptidase S1B family
CAH07_19885	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CAH07_19890	COG1917	Cupin 2, conserved barrel domain protein
CAH07_19890	COG2207	Transcriptional regulator
CAH07_19895	COG0697	spore germination
CAH07_19900	COG3409	Peptidoglycan-binding domain 1 protein
CAH07_19910	COG2271	Major facilitator Superfamily
CAH07_19915	COG1846	Transcriptional regulator
CAH07_19915	COG0456	acetyltransferase
CAH07_19930	COG2271	Major facilitator Superfamily
CAH07_19935	COG0584	glycerophosphoryl diester phosphodiesterase
CAH07_19940	COG0531	amino acid
CAH07_19950	COG2124	cytochrome p450
CAH07_19970	COG1113	amino acid transport
CAH07_19985	COG0515	serine threonine protein kinase
CAH07_19995	COG0642	Histidine kinase
CAH07_20000	COG0745	RESPONSE REGULATOR receiver
CAH07_20005	COG0596	Alpha beta hydrolase
CAH07_20020	COG2814	Major facilitator Superfamily
CAH07_20025	COG0640	Transcriptional regulator
CAH07_20030	COG5609	conserved protein (DUF2294)
CAH07_20040	COG0288	reversible hydration of carbon dioxide
CAH07_20045	COG3002	Belongs to the UPF0753 family
CAH07_20050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CAH07_20055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CAH07_20060	COG2169	Transcriptional regulator
CAH07_20065	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CAH07_20075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CAH07_20080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CAH07_20085	COG4856	YbbR-like protein
CAH07_20090	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CAH07_20095	COG5662	AntiSigma factor
CAH07_20100	COG1595	DNA-templated transcription, initiation
CAH07_20130	COG1683	Conserved Protein
CAH07_20135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAH07_20140	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CAH07_20145	COG1737	Transcriptional regulator
CAH07_20150	COG1263	PTS System
CAH07_20150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAH07_20155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CAH07_20160	COG1472	Belongs to the glycosyl hydrolase 3 family
CAH07_20165	COG3876	Protein conserved in bacteria
CAH07_20170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CAH07_20170	COG2207	Transcriptional regulator
CAH07_20175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CAH07_20180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAH07_20185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAH07_20190	COG2819	hydrolase of the alpha beta superfamily
CAH07_20195	COG0385	Bile acid
CAH07_20200	COG0659	secondary active sulfate transmembrane transporter activity
CAH07_20375	COG0726	polysaccharide deacetylase
CAH07_20380	COG2194	sulfuric ester hydrolase activity
CAH07_20390	COG0489	protein tyrosine kinase activity
CAH07_20395	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAH07_20405	COG2226	methyltransferase
CAH07_20410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CAH07_20415	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CAH07_20420	COG0101	tRNA pseudouridine synthase activity
CAH07_20425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CAH07_20430	COG1122	ATPase activity
CAH07_20435	COG1122	ATPase activity
CAH07_20440	COG0203	ribosomal protein L17
CAH07_20445	COG0202	RNA polymerase activity
CAH07_20450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CAH07_20455	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CAH07_20460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CAH07_20465	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CAH07_20470	COG2163	COG2163 Ribosomal protein L14E L6E L27E
CAH07_20475	COG0024	Methionine aminopeptidase
CAH07_20480	COG0563	adenylate kinase activity
CAH07_20485	COG0201	protein transport
CAH07_20490	COG0200	Binds to the 23S rRNA
CAH07_20495	COG1841	ribosomal large subunit assembly
CAH07_20500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CAH07_20505	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CAH07_20510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CAH07_20515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CAH07_20525	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CAH07_20535	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CAH07_20540	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CAH07_20545	COG0255	Belongs to the universal ribosomal protein uL29 family
CAH07_20550	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CAH07_20555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CAH07_20560	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CAH07_20565	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CAH07_20570	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CAH07_20575	COG0089	rRNA binding
CAH07_20580	COG0088	Forms part of the polypeptide exit tunnel
CAH07_20585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CAH07_20590	COG0051	transcription antitermination factor activity, RNA binding
CAH07_20595	COG0596	Alpha beta hydrolase
CAH07_20600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CAH07_20605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAH07_20610	COG0049	tRNA binding
CAH07_20615	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CAH07_20620	COG1358	cellular component organization or biogenesis
CAH07_20625	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CAH07_20630	COG0085	RNA polymerase activity
CAH07_20635	COG2813	Specifically methylates the guanine in position
CAH07_20640	COG0222	ribosome binding
CAH07_20645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CAH07_20650	COG0081	regulation of translation
CAH07_20655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CAH07_20660	COG0250	Participates in transcription elongation, termination and antitermination
CAH07_20665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAH07_20670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CAH07_20675	COG1595	DNA-templated transcription, initiation
CAH07_20680	COG3688	RNA-binding protein containing a PIN domain
CAH07_20685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAH07_20690	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CAH07_20695	COG0215	cysteine-tRNA ligase activity
CAH07_20700	COG1045	serine acetyltransferase
CAH07_20710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAH07_20715	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CAH07_20720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CAH07_20725	COG4956	integral membrane protein (PIN domain superfamily)
CAH07_20730	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CAH07_20735	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CAH07_20740	COG0542	response to heat
CAH07_20745	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CAH07_20750	COG3880	PFAM UvrB UvrC protein
CAH07_20755	COG4463	regulation of RNA biosynthetic process
CAH07_20835	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CAH07_20840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CAH07_20845	COG1396	sequence-specific DNA binding
CAH07_20850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CAH07_20855	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CAH07_20860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CAH07_20865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CAH07_20870	COG0512	Glutamine amidotransferase of anthranilate synthase
CAH07_20875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CAH07_20880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CAH07_20885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAH07_20890	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CAH07_20895	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CAH07_20900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAH07_20910	COG0037	tRNA processing
CAH07_20915	COG0515	serine threonine protein kinase
CAH07_20920	COG2304	oxidoreductase activity
CAH07_20925	COG2208	phosphoserine phosphatase activity
CAH07_20940	COG1098	S1 RNA binding domain
CAH07_20945	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CAH07_20960	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CAH07_20965	COG3956	TIGRFAM MazG family protein
CAH07_20970	COG2244	polysaccharide biosynthetic process
CAH07_20975	COG2002	toxin-antitoxin pair type II binding
CAH07_20980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CAH07_20990	COG0193	aminoacyl-tRNA hydrolase activity
CAH07_20995	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CAH07_21000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CAH07_21005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CAH07_21010	COG2088	sporulation resulting in formation of a cellular spore
CAH07_21015	COG0251	oxidation-reduction process
CAH07_21020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CAH07_21025	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CAH07_21035	COG4466	Protein conserved in bacteria
CAH07_21045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CAH07_21050	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CAH07_21055	COG3584	3D domain protein
CAH07_21055	COG3583	domain protein
CAH07_21060	COG0084	hydrolase, TatD family'
CAH07_21065	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAH07_21065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAH07_21070	COG2002	toxin-antitoxin pair type II binding
CAH07_21075	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CAH07_21080	COG2827	Endonuclease containing a URI domain
CAH07_21085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CAH07_21090	COG4467	Involved in initiation control of chromosome replication
CAH07_21095	COG1774	PSP1 C-terminal conserved region
CAH07_21100	COG0470	DNA polymerase III
CAH07_21105	COG1728	Protein conserved in bacteria
CAH07_21110	COG3870	Protein conserved in bacteria
CAH07_21115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CAH07_21120	COG1982	Orn Lys Arg decarboxylase major
CAH07_21125	COG3853	Toxic anion resistance protein (TelA)
CAH07_21130	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CAH07_21175	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CAH07_21180	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CAH07_21185	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CAH07_21195	COG0590	tRNA wobble adenosine to inosine editing
CAH07_21200	COG1335	isochorismatase
CAH07_21205	COG3858	chitin binding
CAH07_21205	COG1388	LysM domain
CAH07_21210	COG1428	Deoxynucleoside kinase
CAH07_21215	COG1428	Deoxynucleoside kinase
CAH07_21225	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CAH07_21230	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CAH07_21235	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CAH07_21240	COG1686	Belongs to the peptidase S11 family
CAH07_21245	COG0516	GMP reductase activity
CAH07_21245	COG0517	IMP dehydrogenase activity
CAH07_21280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CAH07_21285	COG0187	DNA topoisomerase II activity
CAH07_21295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CAH07_21300	COG2501	S4 domain
CAH07_21305	COG0592	DNA-directed DNA polymerase activity