locus-tag	class	description
OB04_00001	COG1686	Belongs to the peptidase S11 family
OB04_00002	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OB04_00003	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OB04_00004	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OB04_00006	COG1428	Deoxynucleoside kinase
OB04_00007	COG1428	Deoxynucleoside kinase
OB04_00008	COG3858	chitin binding
OB04_00008	COG1388	LysM domain
OB04_00009	COG1335	isochorismatase
OB04_00010	COG0590	tRNA wobble adenosine to inosine editing
OB04_00011	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OB04_00012	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OB04_00013	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OB04_00022	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OB04_00023	COG3853	Toxic anion resistance protein (TelA)
OB04_00024	COG1982	Orn Lys Arg decarboxylase major
OB04_00025	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OB04_00026	COG3870	Protein conserved in bacteria
OB04_00027	COG1728	Protein conserved in bacteria
OB04_00028	COG0470	DNA polymerase III
OB04_00029	COG1774	PSP1 C-terminal conserved region
OB04_00030	COG4467	Involved in initiation control of chromosome replication
OB04_00031	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OB04_00032	COG2827	Endonuclease containing a URI domain
OB04_00033	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OB04_00034	COG2002	toxin-antitoxin pair type II binding
OB04_00035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OB04_00035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OB04_00036	COG0084	hydrolase, TatD family'
OB04_00037	COG3583	domain protein
OB04_00037	COG3584	3D domain protein
OB04_00038	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OB04_00039	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OB04_00041	COG4466	Protein conserved in bacteria
OB04_00042	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OB04_00043	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OB04_00044	COG0251	oxidation-reduction process
OB04_00045	COG2088	sporulation resulting in formation of a cellular spore
OB04_00046	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OB04_00047	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OB04_00048	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OB04_00049	COG0193	aminoacyl-tRNA hydrolase activity
OB04_00051	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OB04_00052	COG2002	toxin-antitoxin pair type II binding
OB04_00053	COG2244	polysaccharide biosynthetic process
OB04_00054	COG3956	TIGRFAM MazG family protein
OB04_00055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OB04_00058	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OB04_00059	COG1098	S1 RNA binding domain
OB04_00062	COG2208	phosphoserine phosphatase activity
OB04_00063	COG2304	oxidoreductase activity
OB04_00064	COG0515	serine threonine protein kinase
OB04_00065	COG0037	tRNA processing
OB04_00067	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OB04_00068	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OB04_00069	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OB04_00070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OB04_00071	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OB04_00072	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OB04_00073	COG0512	Glutamine amidotransferase of anthranilate synthase
OB04_00074	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OB04_00075	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OB04_00076	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OB04_00077	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OB04_00078	COG1396	sequence-specific DNA binding
OB04_00079	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OB04_00080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OB04_00086	COG4463	regulation of RNA biosynthetic process
OB04_00087	COG3880	PFAM UvrB UvrC protein
OB04_00088	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OB04_00089	COG0542	response to heat
OB04_00090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OB04_00091	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OB04_00092	COG4956	integral membrane protein (PIN domain superfamily)
OB04_00093	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OB04_00094	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OB04_00095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OB04_00096	COG1045	serine acetyltransferase
OB04_00097	COG0215	cysteine-tRNA ligase activity
OB04_00098	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OB04_00099	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OB04_00100	COG3688	RNA-binding protein containing a PIN domain
OB04_00101	COG1595	DNA-templated transcription, initiation
OB04_00102	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OB04_00103	COG0250	Participates in transcription elongation, termination and antitermination
OB04_00104	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OB04_00105	COG0081	regulation of translation
OB04_00106	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OB04_00107	COG0222	ribosome binding
OB04_00108	COG2813	Specifically methylates the guanine in position
OB04_00109	COG0085	RNA polymerase activity
OB04_00110	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OB04_00111	COG1358	cellular component organization or biogenesis
OB04_00112	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OB04_00113	COG0049	tRNA binding
OB04_00114	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OB04_00115	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OB04_00116	COG0596	Alpha beta hydrolase
OB04_00117	COG0051	transcription antitermination factor activity, RNA binding
OB04_00118	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OB04_00119	COG0088	Forms part of the polypeptide exit tunnel
OB04_00120	COG0089	rRNA binding
OB04_00121	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OB04_00122	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OB04_00123	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OB04_00124	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OB04_00125	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OB04_00126	COG0255	Belongs to the universal ribosomal protein uL29 family
OB04_00127	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OB04_00128	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OB04_00130	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OB04_00132	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OB04_00133	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OB04_00134	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OB04_00136	COG1841	ribosomal large subunit assembly
OB04_00137	COG0200	Binds to the 23S rRNA
OB04_00138	COG0201	protein transport
OB04_00139	COG0563	adenylate kinase activity
OB04_00140	COG0024	Methionine aminopeptidase
OB04_00141	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OB04_00142	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OB04_00143	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OB04_00144	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OB04_00145	COG0202	RNA polymerase activity
OB04_00146	COG0203	ribosomal protein L17
OB04_00147	COG1122	ATPase activity
OB04_00148	COG1122	ATPase activity
OB04_00149	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OB04_00150	COG0101	tRNA pseudouridine synthase activity
OB04_00151	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OB04_00152	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OB04_00153	COG2226	methyltransferase
OB04_00155	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_00156	COG0489	protein tyrosine kinase activity
OB04_00158	COG2194	sulfuric ester hydrolase activity
OB04_00159	COG0726	polysaccharide deacetylase
OB04_00165	COG0659	secondary active sulfate transmembrane transporter activity
OB04_00167	COG0385	Bile acid
OB04_00168	COG2819	hydrolase of the alpha beta superfamily
OB04_00169	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_00170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_00171	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_00172	COG2207	Transcriptional regulator
OB04_00172	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_00173	COG3876	Protein conserved in bacteria
OB04_00174	COG1472	Belongs to the glycosyl hydrolase 3 family
OB04_00175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OB04_00176	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_00176	COG1263	PTS System
OB04_00177	COG1737	Transcriptional regulator
OB04_00178	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OB04_00179	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_00180	COG1683	Conserved Protein
OB04_00186	COG1595	DNA-templated transcription, initiation
OB04_00187	COG5662	AntiSigma factor
OB04_00188	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OB04_00189	COG4856	YbbR-like protein
OB04_00190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OB04_00191	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OB04_00192	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OB04_00193	COG2169	Transcriptional regulator
OB04_00194	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OB04_00195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OB04_00196	COG3002	Belongs to the UPF0753 family
OB04_00197	COG0288	reversible hydration of carbon dioxide
OB04_00199	COG5609	conserved protein (DUF2294)
OB04_00200	COG0640	Transcriptional regulator
OB04_00201	COG2814	Major facilitator Superfamily
OB04_00203	COG0596	Alpha beta hydrolase
OB04_00204	COG0745	RESPONSE REGULATOR receiver
OB04_00205	COG0642	Histidine kinase
OB04_00207	COG0515	serine threonine protein kinase
OB04_00210	COG1113	amino acid transport
OB04_00213	COG2602	Beta-lactamase
OB04_00214	COG2124	cytochrome p450
OB04_00216	COG0531	amino acid
OB04_00217	COG0584	glycerophosphoryl diester phosphodiesterase
OB04_00218	COG2271	Major facilitator Superfamily
OB04_00220	COG1846	Transcriptional regulator
OB04_00220	COG0456	acetyltransferase
OB04_00221	COG2271	Major facilitator Superfamily
OB04_00223	COG3409	Peptidoglycan-binding domain 1 protein
OB04_00224	COG0697	spore germination
OB04_00225	COG2207	Transcriptional regulator
OB04_00225	COG1917	Cupin 2, conserved barrel domain protein
OB04_00226	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OB04_00227	COG3591	Belongs to the peptidase S1B family
OB04_00229	COG0596	Alpha beta hydrolase
OB04_00230	COG1183	phosphatidylcholine synthase activity
OB04_00231	COG0586	Pfam SNARE associated Golgi protein
OB04_00232	COG0688	phosphatidylethanolamine metabolic process
OB04_00234	COG2312	Erythromycin esterase
OB04_00235	COG2207	Transcriptional regulator
OB04_00237	COG1301	dicarboxylic acid transport
OB04_00238	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_00238	COG2190	(PTS) system
OB04_00238	COG1263	PTS System
OB04_00239	COG0363	glucosamine-6-phosphate deaminase activity
OB04_00242	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OB04_00243	COG0833	amino acid
OB04_00244	COG2040	homocysteine
OB04_00246	COG1115	amino acid carrier protein
OB04_00247	COG2066	Belongs to the glutaminase family
OB04_00248	COG4191	Histidine kinase
OB04_00249	COG0784	Response regulator, receiver
OB04_00250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OB04_00251	COG1012	belongs to the aldehyde dehydrogenase family
OB04_00252	COG2271	Major facilitator Superfamily
OB04_00253	COG4948	Mandelate Racemase Muconate Lactonizing
OB04_00254	COG2186	Transcriptional regulator
OB04_00255	COG2721	sulfolactate sulfo-lyase activity
OB04_00256	COG3173	Aminoglycoside phosphotransferase
OB04_00258	COG0697	spore germination
OB04_00259	COG0745	RESPONSE REGULATOR receiver
OB04_00260	COG2205	protein histidine kinase activity
OB04_00261	COG1131	(ABC) transporter
OB04_00264	COG3773	Cell wall hydrolase
OB04_00265	COG2304	oxidoreductase activity
OB04_00266	COG3540	Alkaline phosphatase
OB04_00267	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OB04_00268	COG0805	protein transport
OB04_00269	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OB04_00270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OB04_00271	COG0477	Major facilitator Superfamily
OB04_00272	COG1309	transcriptional regulator
OB04_00273	COG0252	asparaginase activity
OB04_00274	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OB04_00275	COG1714	RDD family
OB04_00276	COG3012	SEC-C Motif Domain Protein
OB04_00276	COG1405	negative regulation of cell septum assembly
OB04_00277	COG3290	protein histidine kinase activity
OB04_00278	COG3279	Response regulator of the LytR AlgR family
OB04_00279	COG4555	ABC transporter
OB04_00280	COG1668	transmembrane transport
OB04_00281	COG0667	Aldo Keto reductase
OB04_00283	COG1595	DNA-templated transcription, initiation
OB04_00284	COG1595	DNA-templated transcription, initiation
OB04_00285	COG1876	peptidase activity
OB04_00286	COG0457	Tetratricopeptide repeat
OB04_00287	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_00288	COG0366	Alpha amylase catalytic
OB04_00289	COG0803	Belongs to the bacterial solute-binding protein 9 family
OB04_00290	COG1121	(ABC) transporter
OB04_00291	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OB04_00292	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_00293	COG2310	stress, protein
OB04_00294	COG2310	stress, protein
OB04_00295	COG2310	stress, protein
OB04_00296	COG0861	Integral membrane protein TerC family
OB04_00298	COG3853	Toxic anion resistance protein (TelA)
OB04_00299	COG0477	Major facilitator Superfamily
OB04_00300	COG2814	Major facilitator Superfamily
OB04_00301	COG0640	Transcriptional regulator
OB04_00302	COG0517	IMP dehydrogenase activity
OB04_00302	COG4175	Glycine betaine
OB04_00303	COG4176	ABC-type proline glycine betaine transport system permease component
OB04_00304	COG2113	Glycine betaine
OB04_00305	COG1473	amidohydrolase
OB04_00306	COG1288	antiporter activity
OB04_00308	COG0366	Alpha amylase catalytic
OB04_00309	COG0039	L-malate dehydrogenase activity
OB04_00310	COG1620	l-lactate permease
OB04_00311	COG2814	Major facilitator Superfamily
OB04_00312	COG1846	Transcriptional regulator
OB04_00313	COG1280	lysine exporter protein (LysE YggA)
OB04_00314	COG3403	YqcI/YcgG family
OB04_00315	COG1113	amino acid transport
OB04_00316	COG3665	Urea carboxylase-associated protein
OB04_00317	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OB04_00318	COG1660	Displays ATPase and GTPase activities
OB04_00320	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OB04_00321	COG2226	methyltransferase
OB04_00322	COG0583	DNA-binding transcription factor activity
OB04_00323	COG3458	cephalosporin-C deacetylase activity
OB04_00324	COG3541	Predicted nucleotidyltransferase
OB04_00325	COG0506	proline dehydrogenase activity
OB04_00326	COG1012	belongs to the aldehyde dehydrogenase family
OB04_00327	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OB04_00328	COG2508	Transcriptional regulator
OB04_00329	COG3689	TIGRFAM TIGR03943 family protein
OB04_00330	COG0701	Predicted permease
OB04_00331	COG2267	carboxylic ester hydrolase activity
OB04_00332	COG0492	ferredoxin-NADP+ reductase activity
OB04_00333	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OB04_00333	COG1587	Uroporphyrinogen-III synthase
OB04_00334	COG2146	nitrite reductase [NAD(P)H] activity
OB04_00335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OB04_00336	COG0243	molybdopterin cofactor binding
OB04_00337	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OB04_00339	COG2223	nitrite transmembrane transporter activity
OB04_00340	COG1469	GTP cyclohydrolase I activity
OB04_00341	COG1376	ErfK ybiS ycfS ynhG family protein
OB04_00342	COG0523	cobalamin synthesis protein
OB04_00343	COG0765	amino acid transport
OB04_00344	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_00346	COG1714	RDD family
OB04_00348	COG2723	6-phospho-beta-galactosidase activity
OB04_00350	COG3209	COG3209 Rhs family protein
OB04_00351	COG3290	protein histidine kinase activity
OB04_00351	COG0840	transmembrane signaling receptor activity
OB04_00352	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OB04_00353	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
OB04_00354	COG1733	regulation of RNA biosynthetic process
OB04_00355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_00356	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_00357	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_00358	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OB04_00359	COG2814	Major facilitator Superfamily
OB04_00361	COG0697	spore germination
OB04_00362	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_00364	COG2364	Membrane
OB04_00365	COG1126	abc transporter atp-binding protein
OB04_00366	COG0765	amino acid transport
OB04_00367	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_00368	COG0583	DNA-binding transcription factor activity
OB04_00369	COG0163	prenyltransferase activity
OB04_00370	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OB04_00373	COG0596	Alpha beta hydrolase
OB04_00374	COG3104	oligopeptide transport
OB04_00375	COG5434	Belongs to the glycosyl hydrolase 28 family
OB04_00377	COG0697	spore germination
OB04_00379	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OB04_00380	COG1136	(ABC) transporter
OB04_00381	COG0577	efflux transmembrane transporter activity
OB04_00382	COG0745	RESPONSE REGULATOR receiver
OB04_00383	COG3850	Histidine kinase
OB04_00383	COG5002	protein histidine kinase activity
OB04_00384	COG0457	Tetratricopeptide repeat
OB04_00388	COG0527	aspartate kinase activity
OB04_00389	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_00390	COG4605	iron ion homeostasis
OB04_00391	COG4604	ABC transporter, ATP-binding protein
OB04_00392	COG4607	ABC-type enterochelin transport system periplasmic component
OB04_00393	COG2814	Major facilitator Superfamily
OB04_00394	COG1309	transcriptional regulator
OB04_00395	COG0778	Nitroreductase
OB04_00396	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OB04_00397	COG0640	Transcriptional regulator
OB04_00398	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_00399	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OB04_00400	COG1012	belongs to the aldehyde dehydrogenase family
OB04_00401	COG4975	Glucose uptake
OB04_00402	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_00403	COG4549	nuclear export factor GLE1
OB04_00404	COG2372	response to copper ion
OB04_00404	COG1276	copper resistance
OB04_00405	COG1349	DNA-binding transcription factor activity
OB04_00407	COG2213	PTS system mannitol-specific
OB04_00408	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_00409	COG0246	Mannitol dehydrogenase
OB04_00410	COG0473	3-isopropylmalate dehydrogenase activity
OB04_00411	COG0681	Belongs to the peptidase S26 family
OB04_00412	COG0412	Dienelactone hydrolase
OB04_00413	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OB04_00415	COG0561	phosphatase activity
OB04_00416	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OB04_00417	COG1914	H( )-stimulated, divalent metal cation uptake system
OB04_00418	COG4336	lyase activity
OB04_00419	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OB04_00420	COG1984	allophanate hydrolase subunit 2
OB04_00421	COG1414	Transcriptional regulator
OB04_00422	COG2755	lipolytic protein G-D-S-L family
OB04_00424	COG2329	Antibiotic biosynthesis monooxygenase
OB04_00425	COG0768	penicillin binding
OB04_00426	COG4989	oxidoreductase activity
OB04_00427	COG3711	transcriptional antiterminator
OB04_00428	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_00429	COG2226	methyltransferase
OB04_00430	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_00431	COG1917	Cupin 2, conserved barrel domain protein
OB04_00432	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_00433	COG3871	stress protein (general stress protein 26)
OB04_00435	COG2814	Major facilitator Superfamily
OB04_00436	COG1522	sequence-specific DNA binding
OB04_00437	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OB04_00437	COG0551	DNA topoisomerase type I activity
OB04_00438	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OB04_00439	COG3706	GGDEF domain
OB04_00440	COG5298	Protein conserved in bacteria
OB04_00441	COG1215	transferase activity, transferring glycosyl groups
OB04_00443	COG0531	amino acid
OB04_00444	COG0494	nUDIX hydrolase
OB04_00445	COG0028	Belongs to the TPP enzyme family
OB04_00447	COG1914	H( )-stimulated, divalent metal cation uptake system
OB04_00448	COG2261	transglycosylase associated protein
OB04_00449	COG4876	unkown
OB04_00450	COG2217	Heavy metal translocating P-type atpase
OB04_00451	COG3729	General stress protein
OB04_00452	COG0662	Cupin 2, conserved barrel domain protein
OB04_00453	COG2329	Antibiotic biosynthesis monooxygenase
OB04_00454	COG3546	catalase activity
OB04_00455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OB04_00456	COG3290	protein histidine kinase activity
OB04_00457	COG4565	transcriptional regulatory protein
OB04_00458	COG1301	dicarboxylic acid transport
OB04_00459	COG0628	permease
OB04_00461	COG1131	(ABC) transporter
OB04_00462	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OB04_00464	COG1960	acyl-CoA dehydrogenase activity
OB04_00467	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OB04_00468	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_00469	COG1181	Belongs to the D-alanine--D-alanine ligase family
OB04_00470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OB04_00471	COG0513	Belongs to the DEAD box helicase family
OB04_00472	COG3402	PFAM membrane-flanked domain
OB04_00473	COG3428	Bacterial PH domain
OB04_00474	COG0705	Rhomboid family
OB04_00475	COG0736	holo-[acyl-carrier-protein] synthase activity
OB04_00476	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OB04_00477	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OB04_00478	COG0864	Transcriptional regulator
OB04_00479	COG2337	Toxic component of a toxin-antitoxin (TA) module
OB04_00480	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_00481	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_00482	COG2172	sigma factor antagonist activity
OB04_00483	COG2208	phosphoserine phosphatase activity
OB04_00484	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_00485	COG2172	sigma factor antagonist activity
OB04_00486	COG1191	sigma factor activity
OB04_00487	COG2208	phosphoserine phosphatase activity
OB04_00488	COG2183	response to ionizing radiation
OB04_00489	COG3091	SprT-like family
OB04_00500	COG5444	nuclease activity
OB04_00501	COG1476	TRANSCRIPTIONal
OB04_00503	COG3239	Fatty acid desaturase
OB04_00505	COG1278	Cold shock
OB04_00506	COG1329	Transcriptional regulator
OB04_00507	COG0697	spore germination
OB04_00508	COG2207	Transcriptional regulator
OB04_00508	COG1917	Cupin 2, conserved barrel domain protein
OB04_00509	COG0697	spore germination
OB04_00510	COG3708	Transcriptional regulator
OB04_00510	COG2207	Transcriptional regulator
OB04_00512	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_00513	COG0477	Major facilitator Superfamily
OB04_00515	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
OB04_00521	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_00522	COG1309	transcriptional regulator
OB04_00523	COG0697	spore germination
OB04_00524	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_00525	COG2030	dehydratase
OB04_00526	COG3545	Serine hydrolase
OB04_00527	COG1733	regulation of RNA biosynthetic process
OB04_00528	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_00529	COG1733	regulation of RNA biosynthetic process
OB04_00532	COG2814	Major facilitator Superfamily
OB04_00533	COG1309	transcriptional regulator
OB04_00534	COG0640	Transcriptional regulator
OB04_00535	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OB04_00536	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_00537	COG0697	spore germination
OB04_00538	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_00539	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OB04_00540	COG0640	Transcriptional regulator
OB04_00541	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OB04_00543	COG4585	Histidine kinase
OB04_00544	COG2197	response regulator
OB04_00545	COG2409	Drug exporters of the RND superfamily
OB04_00547	COG0596	Alpha beta hydrolase
OB04_00548	COG1811	Na channel or pump
OB04_00549	COG0789	Transcriptional regulator
OB04_00549	COG4978	Transcriptional regulator
OB04_00550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OB04_00551	COG0778	Nitroreductase
OB04_00552	COG0346	lactoylglutathione lyase activity
OB04_00553	COG2259	Doxx family
OB04_00554	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_00558	COG2323	membrane
OB04_00561	COG0071	Belongs to the small heat shock protein (HSP20) family
OB04_00564	COG1309	transcriptional regulator
OB04_00566	COG0456	acetyltransferase
OB04_00568	COG1113	amino acid transport
OB04_00569	COG2318	DinB family
OB04_00570	COG1846	Transcriptional regulator
OB04_00571	COG1033	growth of symbiont in host cell
OB04_00571	COG2409	Drug exporters of the RND superfamily
OB04_00572	COG0778	Nitroreductase
OB04_00573	COG1846	Transcriptional regulator
OB04_00574	COG2814	Major facilitator Superfamily
OB04_00575	COG0730	response to heat
OB04_00576	COG1802	Transcriptional regulator
OB04_00577	COG3858	chitin binding
OB04_00577	COG1388	LysM domain
OB04_00578	COG1819	glycosyl
OB04_00580	COG1785	Belongs to the alkaline phosphatase family
OB04_00581	COG5646	InterPro IPR014922
OB04_00583	COG0454	-acetyltransferase
OB04_00584	COG1078	dGTPase activity
OB04_00585	COG1388	LysM domain
OB04_00586	COG2814	Major facilitator Superfamily
OB04_00587	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OB04_00588	COG1447	Phosphotransferase system cellobiose-specific component IIA
OB04_00589	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OB04_00590	COG2723	6-phospho-beta-galactosidase activity
OB04_00591	COG2188	Transcriptional regulator
OB04_00592	COG1940	carbohydrate kinase activity
OB04_00593	COG1482	cell wall glycoprotein biosynthetic process
OB04_00594	COG4124	Belongs to the glycosyl hydrolase 26 family
OB04_00605	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OB04_00606	COG0802	atpase or kinase
OB04_00607	COG1214	PFAM Peptidase M22, glycoprotease
OB04_00608	COG0456	acetyltransferase
OB04_00609	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OB04_00610	COG0488	(ABC) transporter
OB04_00611	COG0315	cyclic pyranopterin monophosphate synthase activity
OB04_00612	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OB04_00613	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OB04_00614	COG0805	protein transport
OB04_00616	COG1266	CAAX protease self-immunity
OB04_00617	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OB04_00618	COG0459	protein refolding
OB04_00619	COG4974	Belongs to the 'phage' integrase family
OB04_00620	COG2856	Zn peptidase
OB04_00622	COG1396	sequence-specific DNA binding
OB04_00635	COG3935	DnaD domain protein
OB04_00636	COG1484	DNA-dependent DNA replication
OB04_00658	COG3677	Transposase
OB04_00661	COG5484	DNA packaging
OB04_00662	COG1783	phage Terminase large subunit
OB04_00686	COG5632	N-Acetylmuramoyl-L-alanine amidase
OB04_00686	COG3409	Peptidoglycan-binding domain 1 protein
OB04_00692	COG1073	alpha beta
OB04_00693	COG0457	Tetratricopeptide repeat
OB04_00694	COG1063	alcohol dehydrogenase
OB04_00695	COG2211	Major facilitator Superfamily
OB04_00696	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OB04_00697	COG1842	Phage shock protein A
OB04_00698	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OB04_00699	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OB04_00700	COG4260	virion core protein, lumpy skin disease virus
OB04_00702	COG2814	Major facilitator Superfamily
OB04_00703	COG1063	alcohol dehydrogenase
OB04_00704	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OB04_00705	COG0823	Involved in the tonB-independent uptake of proteins
OB04_00708	COG2267	carboxylic ester hydrolase activity
OB04_00710	COG2132	Multicopper oxidase
OB04_00711	COG1113	amino acid transport
OB04_00712	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OB04_00713	COG0714	Associated with various cellular activities
OB04_00714	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OB04_00715	COG1305	Transglutaminase-like
OB04_00716	COG0519	Catalyzes the synthesis of GMP from XMP
OB04_00716	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OB04_00717	COG2252	PERMEase
OB04_00718	COG3064	Membrane
OB04_00720	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
OB04_00722	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OB04_00723	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OB04_00724	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OB04_00725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OB04_00726	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OB04_00727	COG0047	phosphoribosylformylglycinamidine synthase activity
OB04_00728	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OB04_00729	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OB04_00730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OB04_00731	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OB04_00732	COG0138	bifunctional purine biosynthesis protein purh
OB04_00733	COG0151	Belongs to the GarS family
OB04_00734	COG1522	sequence-specific DNA binding
OB04_00735	COG0531	amino acid
OB04_00737	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OB04_00738	COG1470	cell adhesion involved in biofilm formation
OB04_00739	COG4496	protein, YerC YecD
OB04_00740	COG0069	glutamate synthase activity
OB04_00742	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OB04_00743	COG0210	DNA helicase
OB04_00744	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OB04_00745	COG4851	CamS sex pheromone cAM373 precursor
OB04_00746	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OB04_00747	COG1285	pathogenesis
OB04_00748	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OB04_00749	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OB04_00750	COG0154	amidase activity
OB04_00751	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OB04_00752	COG1309	transcriptional regulator
OB04_00753	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OB04_00754	COG1597	lipid kinase activity
OB04_00755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OB04_00757	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OB04_00759	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OB04_00763	COG5444	nuclease activity
OB04_00764	COG3391	amine dehydrogenase activity
OB04_00765	COG0457	Tetratricopeptide repeat
OB04_00767	COG0217	transcriptional regulatory protein
OB04_00769	COG1309	transcriptional regulator
OB04_00770	COG3631	Ketosteroid isomerase-related protein
OB04_00771	COG0702	epimerase
OB04_00774	COG3546	catalase activity
OB04_00775	COG0454	-acetyltransferase
OB04_00777	COG5578	integral membrane protein
OB04_00778	COG2972	Histidine kinase
OB04_00779	COG2207	Transcriptional regulator
OB04_00779	COG4753	response regulator
OB04_00780	COG1653	transport
OB04_00781	COG1175	transmembrane transport
OB04_00782	COG0395	ABC-type sugar transport system, permease component
OB04_00783	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OB04_00784	COG2207	Transcriptional regulator
OB04_00785	COG2755	lipolytic protein G-D-S-L family
OB04_00787	COG5578	integral membrane protein
OB04_00788	COG3401	FG-GAP repeat protein
OB04_00789	COG3401	FG-GAP repeat protein
OB04_00790	COG2755	lipolytic protein G-D-S-L family
OB04_00791	COG1874	Beta-galactosidase
OB04_00793	COG1653	transport
OB04_00794	COG4209	transmembrane transport
OB04_00795	COG0395	ABC-type sugar transport system, permease component
OB04_00796	COG1486	melibiose metabolic process
OB04_00797	COG2323	membrane
OB04_00798	COG2329	Antibiotic biosynthesis monooxygenase
OB04_00799	COG0346	lactoylglutathione lyase activity
OB04_00802	COG5583	Uncharacterized small protein (DUF2292)
OB04_00803	COG0670	Belongs to the BI1 family
OB04_00804	COG1846	Transcriptional regulator
OB04_00805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OB04_00807	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OB04_00807	COG2124	cytochrome p450
OB04_00808	COG1368	sulfuric ester hydrolase activity
OB04_00809	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OB04_00810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OB04_00811	COG1442	glycosyl transferase family 8
OB04_00812	COG1216	Glycosyl transferase, family 2
OB04_00813	COG1442	glycosyl transferase family 8
OB04_00814	COG2223	nitrite transmembrane transporter activity
OB04_00815	COG1011	Hydrolase
OB04_00816	COG0531	amino acid
OB04_00817	COG1012	belongs to the aldehyde dehydrogenase family
OB04_00818	COG0840	transmembrane signaling receptor activity
OB04_00819	COG0488	(ABC) transporter
OB04_00821	COG0789	Transcriptional regulator
OB04_00822	COG2814	Major facilitator Superfamily
OB04_00824	COG0488	(ABC) transporter
OB04_00825	COG0513	Belongs to the DEAD box helicase family
OB04_00826	COG0456	acetyltransferase
OB04_00827	COG2130	NADP-dependent
OB04_00828	COG1120	ATPase activity
OB04_00829	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_00830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_00831	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OB04_00834	COG3866	Pectate lyase
OB04_00835	COG0471	metal ion transport
OB04_00836	COG3290	protein histidine kinase activity
OB04_00837	COG4565	transcriptional regulatory protein
OB04_00838	COG3181	Tripartite tricarboxylate transporter family receptor
OB04_00839	COG2851	Citrate transporter
OB04_00840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_00841	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OB04_00842	COG1254	Belongs to the acylphosphatase family
OB04_00843	COG2258	MOSC domain
OB04_00847	COG0024	Methionine aminopeptidase
OB04_00848	COG1263	PTS System
OB04_00848	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_00849	COG1368	sulfuric ester hydrolase activity
OB04_00851	COG1115	amino acid carrier protein
OB04_00852	COG0531	amino acid
OB04_00855	COG0697	spore germination
OB04_00856	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_00856	COG1263	PTS System
OB04_00857	COG0366	Alpha amylase catalytic
OB04_00858	COG2188	Transcriptional regulator
OB04_00859	COG0778	Nitroreductase
OB04_00860	COG0737	Belongs to the 5'-nucleotidase family
OB04_00861	COG0693	protein deglycase activity
OB04_00862	COG2814	Major facilitator Superfamily
OB04_00863	COG4840	Belongs to the UPF0435 family
OB04_00864	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OB04_00865	COG4980	gas vesicle protein
OB04_00866	COG1295	ribonuclease BN
OB04_00868	COG0477	Major facilitator Superfamily
OB04_00869	COG0387	Pfam Sodium calcium exchanger
OB04_00871	COG0668	transmembrane transport
OB04_00872	COG0535	radical SAM domain protein
OB04_00874	COG0726	polysaccharide deacetylase
OB04_00875	COG2084	Dehydrogenase
OB04_00876	COG0598	Magnesium transport protein CorA
OB04_00877	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OB04_00878	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OB04_00880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OB04_00881	COG4637	Psort location Cytoplasmic, score
OB04_00882	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OB04_00883	COG0022	dehydrogenase e1 component
OB04_00884	COG0508	dehydrogenase complex catalyzes the overall conversion of
OB04_00885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OB04_00886	COG3284	Transcriptional regulator
OB04_00888	COG1742	UPF0060 membrane protein
OB04_00892	COG4842	Belongs to the WXG100 family
OB04_00893	COG1486	melibiose metabolic process
OB04_00894	COG1737	Transcriptional regulator
OB04_00895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_00895	COG1263	PTS System
OB04_00896	COG1132	(ABC) transporter
OB04_00897	COG1132	(ABC) transporter
OB04_00898	COG2259	Doxx family
OB04_00899	COG2514	catechol 2,3-dioxygenase activity
OB04_00901	COG4585	Histidine kinase
OB04_00902	COG2197	response regulator
OB04_00903	COG1131	(ABC) transporter
OB04_00904	COG0842	Transport permease protein
OB04_00904	COG1511	domain protein
OB04_00905	COG0842	Transport permease protein
OB04_00906	COG1695	Transcriptional regulator
OB04_00907	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OB04_00908	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OB04_00909	COG1309	transcriptional regulator
OB04_00910	COG2814	Major facilitator Superfamily
OB04_00911	COG2318	DinB family
OB04_00912	COG2814	Major facilitator Superfamily
OB04_00913	COG1846	Transcriptional regulator
OB04_00914	COG0392	lysyltransferase activity
OB04_00914	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OB04_00915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_00916	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_00917	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_00918	COG0384	phenazine biosynthesis protein PhzF
OB04_00919	COG0778	Nitroreductase
OB04_00922	COG1090	epimerase
OB04_00923	COG2137	regulation of response to DNA damage stimulus
OB04_00925	COG2814	Major facilitator Superfamily
OB04_00928	COG3103	Sh3 type 3 domain protein
OB04_00929	COG5658	integral membrane protein
OB04_00930	COG0596	Alpha beta hydrolase
OB04_00931	COG0463	Glycosyl transferase, family 2
OB04_00932	COG4485	Bacterial membrane protein, YfhO
OB04_00933	COG1988	membrane-bound metal-dependent
OB04_00934	COG1194	a g-specific adenine glycosylase
OB04_00936	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_00939	COG3557	Belongs to the UPF0374 family
OB04_00940	COG1132	(ABC) transporter
OB04_00941	COG4129	membrane
OB04_00942	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OB04_00943	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OB04_00944	COG0735	belongs to the Fur family
OB04_00966	COG4326	sporulation control protein
OB04_00968	COG3340	Belongs to the peptidase S51 family
OB04_00969	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OB04_00970	COG0277	FAD linked oxidase domain protein
OB04_00972	COG0753	catalase activity
OB04_00973	COG1116	anion transmembrane transporter activity
OB04_00974	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OB04_00975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OB04_00976	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_00978	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OB04_00980	COG1476	TRANSCRIPTIONal
OB04_00982	COG3382	B3 4 domain protein
OB04_00983	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OB04_00985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OB04_00986	COG0789	Transcriptional regulator
OB04_00987	COG1664	Polymer-forming cytoskeletal
OB04_00988	COG1664	Polymer-forming cytoskeletal
OB04_00989	COG2766	serine protein kinase
OB04_00990	COG2718	Belongs to the UPF0229 family
OB04_00991	COG1846	Transcriptional regulator
OB04_00992	COG1566	PFAM secretion protein HlyD family protein
OB04_00993	COG2814	Major facilitator Superfamily
OB04_00994	COG0655	NAD(P)H dehydrogenase (quinone) activity
OB04_00997	COG1725	Transcriptional regulator
OB04_00998	COG1131	(ABC) transporter
OB04_00999	COG1131	(ABC) transporter
OB04_01000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OB04_01001	COG1278	Cold shock
OB04_01002	COG1464	Belongs to the NlpA lipoprotein family
OB04_01003	COG3706	GGDEF domain
OB04_01004	COG1823	symporter activity
OB04_01008	COG5577	PFAM Coat F domain
OB04_01009	COG4085	toxin activity
OB04_01009	COG0737	Belongs to the 5'-nucleotidase family
OB04_01009	COG1525	nuclease
OB04_01010	COG3764	Sortase (surface protein transpeptidase)
OB04_01011	COG0564	pseudouridine synthase activity
OB04_01013	COG0517	IMP dehydrogenase activity
OB04_01014	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OB04_01015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OB04_01015	COG3153	acetyltransferase
OB04_01016	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OB04_01017	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OB04_01018	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OB04_01019	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OB04_01020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OB04_01021	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OB04_01022	COG2203	Gaf domain
OB04_01022	COG4585	Histidine kinase
OB04_01023	COG2197	response regulator
OB04_01024	COG0431	NADPH-dependent FMN reductase
OB04_01027	COG0791	NLP P60 protein
OB04_01027	COG1388	LysM domain
OB04_01028	COG1959	2 iron, 2 sulfur cluster binding
OB04_01029	COG0668	transmembrane transport
OB04_01030	COG2719	SpoVR family
OB04_01031	COG1785	Belongs to the alkaline phosphatase family
OB04_01032	COG0791	NLP P60 protein
OB04_01032	COG1388	LysM domain
OB04_01033	COG0583	DNA-binding transcription factor activity
OB04_01034	COG0372	Belongs to the citrate synthase family
OB04_01035	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01036	COG0531	amino acid
OB04_01037	COG0733	neurotransmitter:sodium symporter activity
OB04_01038	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_01039	COG0456	acetyltransferase
OB04_01042	COG1595	DNA-templated transcription, initiation
OB04_01043	COG0667	Aldo Keto reductase
OB04_01044	COG0204	Acyl-transferase
OB04_01045	COG1253	flavin adenine dinucleotide binding
OB04_01046	COG0789	Transcriptional regulator
OB04_01047	COG0436	Aminotransferase
OB04_01048	COG1253	flavin adenine dinucleotide binding
OB04_01049	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OB04_01050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OB04_01051	COG0584	glycerophosphoryl diester phosphodiesterase
OB04_01053	COG0668	transmembrane transport
OB04_01054	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OB04_01055	COG0726	polysaccharide deacetylase
OB04_01056	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OB04_01057	COG1757	Na H antiporter
OB04_01058	COG0589	response to stress
OB04_01059	COG1132	(ABC) transporter
OB04_01060	COG1132	(ABC) transporter
OB04_01061	COG0702	epimerase
OB04_01064	COG0189	ligase activity
OB04_01065	COG0189	ligase activity
OB04_01066	COG4399	Belongs to the UPF0754 family
OB04_01067	COG3679	Belongs to the UPF0342 family
OB04_01068	COG4335	DNA alkylation repair
OB04_01069	COG0561	phosphatase activity
OB04_01070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OB04_01071	COG0475	glutathione-regulated potassium exporter activity
OB04_01072	COG0490	domain, Protein
OB04_01074	COG1024	Enoyl-CoA hydratase
OB04_01076	COG4152	abc transporter atp-binding protein
OB04_01077	COG1668	transmembrane transport
OB04_01078	COG0420	3'-5' exonuclease activity
OB04_01079	COG4717	serine-type aminopeptidase activity
OB04_01080	COG3481	metal-dependent phosphohydrolase, HD sub domain
OB04_01082	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OB04_01085	COG1846	Transcriptional regulator
OB04_01086	COG4980	gas vesicle protein
OB04_01089	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OB04_01090	COG0537	adenosine 5'-monophosphoramidase activity
OB04_01091	COG1131	(ABC) transporter
OB04_01092	COG4473	ABC transporter
OB04_01094	COG1473	amidohydrolase
OB04_01095	COG3069	C4-dicarboxylate transmembrane transporter activity
OB04_01097	COG2329	Antibiotic biosynthesis monooxygenase
OB04_01098	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OB04_01099	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OB04_01102	COG1309	transcriptional regulator
OB04_01103	COG1511	domain protein
OB04_01104	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OB04_01105	COG4377	Putative membrane peptidase family (DUF2324)
OB04_01106	COG1363	Peptidase, m42
OB04_01107	COG4405	Protein conserved in bacteria
OB04_01108	COG1301	dicarboxylic acid transport
OB04_01109	COG1234	tRNA 3'-trailer cleavage
OB04_01110	COG0095	Lipoate-protein ligase
OB04_01111	COG0702	epimerase
OB04_01112	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_01114	COG0501	Belongs to the peptidase M48B family
OB04_01116	COG0456	acetyltransferase
OB04_01117	COG0604	alcohol dehydrogenase
OB04_01118	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OB04_01119	COG0406	alpha-ribazole phosphatase activity
OB04_01120	COG0183	Belongs to the thiolase family
OB04_01121	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_01122	COG1268	BioY protein
OB04_01123	COG0840	transmembrane signaling receptor activity
OB04_01124	COG0723	plastoquinol--plastocyanin reductase activity
OB04_01124	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OB04_01125	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01127	COG4903	ComK protein
OB04_01128	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OB04_01133	COG0398	Pfam SNARE associated Golgi protein
OB04_01134	COG0681	Belongs to the peptidase S26 family
OB04_01135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OB04_01136	COG1846	Transcriptional regulator
OB04_01137	COG0738	Major facilitator superfamily
OB04_01138	COG0673	inositol 2-dehydrogenase activity
OB04_01139	COG0561	phosphatase activity
OB04_01140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OB04_01141	COG1609	Transcriptional regulator
OB04_01142	COG3180	Ammonia monooxygenase
OB04_01143	COG2814	Major facilitator Superfamily
OB04_01143	COG0477	Major facilitator Superfamily
OB04_01144	COG4533	DNA binding
OB04_01146	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
OB04_01147	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OB04_01148	COG1074	ATP-dependent DNA helicase activity
OB04_01149	COG0420	3'-5' exonuclease activity
OB04_01150	COG0419	ATPase involved in DNA repair
OB04_01151	COG1403	HNH endonuclease
OB04_01159	COG5337	Spore coat protein CotH
OB04_01160	COG0179	Fumarylacetoacetate (FAA) hydrolase
OB04_01162	COG1404	Belongs to the peptidase S8 family
OB04_01164	COG0367	asparagine synthase
OB04_01165	COG2318	DinB family
OB04_01166	COG1562	ergosterol biosynthetic process
OB04_01167	COG0534	Mate efflux family protein
OB04_01168	COG2207	Transcriptional regulator
OB04_01168	COG1917	Cupin 2, conserved barrel domain protein
OB04_01169	COG1609	Transcriptional regulator
OB04_01170	COG0673	inositol 2-dehydrogenase activity
OB04_01171	COG2318	DinB family
OB04_01174	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_01175	COG1357	PFAM Pentapeptide repeats (8 copies)
OB04_01176	COG2267	carboxylic ester hydrolase activity
OB04_01177	COG0529	Catalyzes the synthesis of activated sulfate
OB04_01178	COG2046	Belongs to the sulfate adenylyltransferase family
OB04_01179	COG0175	sulfate reduction
OB04_01180	COG2045	Belongs to the ComB family
OB04_01181	COG1809	phosphosulfolactate synthase activity
OB04_01182	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_01183	COG4948	Mandelate Racemase Muconate Lactonizing
OB04_01184	COG2814	Major facilitator Superfamily
OB04_01185	COG0454	-acetyltransferase
OB04_01186	COG2153	protein acetylation
OB04_01187	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OB04_01187	COG0646	methionine synthase
OB04_01188	COG1666	GTP binding
OB04_01189	COG2996	Protein conserved in bacteria
OB04_01193	COG1695	Transcriptional regulator
OB04_01196	COG3227	Zinc metalloprotease (Elastase)
OB04_01197	COG1307	EDD domain protein, DegV family
OB04_01198	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_01202	COG0561	phosphatase activity
OB04_01203	COG1073	alpha beta
OB04_01204	COG2151	metal-sulfur cluster biosynthetic enzyme
OB04_01206	COG0277	FAD linked oxidase domain protein
OB04_01207	COG2271	Major facilitator Superfamily
OB04_01208	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OB04_01211	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OB04_01212	COG0505	Belongs to the CarA family
OB04_01213	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OB04_01214	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OB04_01217	COG2267	carboxylic ester hydrolase activity
OB04_01219	COG1744	ABC transporter substrate-binding protein PnrA-like
OB04_01222	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OB04_01223	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OB04_01224	COG5504	Zn-dependent protease
OB04_01225	COG0444	Belongs to the ABC transporter superfamily
OB04_01226	COG4608	Belongs to the ABC transporter superfamily
OB04_01228	COG0601	transmembrane transport
OB04_01229	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OB04_01231	COG0180	Tryptophanyl-tRNA synthetase
OB04_01232	COG4166	transmembrane transport
OB04_01233	COG0601	transmembrane transport
OB04_01234	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OB04_01235	COG0444	Belongs to the ABC transporter superfamily
OB04_01236	COG4608	Belongs to the ABC transporter superfamily
OB04_01237	COG2814	Major facilitator Superfamily
OB04_01238	COG0456	acetyltransferase
OB04_01239	COG1393	Belongs to the ArsC family
OB04_01240	COG0861	Integral membrane protein TerC family
OB04_01241	COG4862	establishment of competence for transformation
OB04_01242	COG4469	Competence protein
OB04_01243	COG1164	Oligoendopeptidase f
OB04_01247	COG2346	COG2346, Truncated hemoglobins
OB04_01248	COG0741	lytic transglycosylase activity
OB04_01249	COG4116	CYTH
OB04_01251	COG2357	RelA SpoT domain protein
OB04_01252	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OB04_01253	COG0564	pseudouridine synthase activity
OB04_01254	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OB04_01255	COG0475	glutathione-regulated potassium exporter activity
OB04_01255	COG0569	domain protein
OB04_01256	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OB04_01257	COG0352	thiamine-phosphate diphosphorylase activity
OB04_01258	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OB04_01259	COG2104	thiamine diphosphate biosynthetic process
OB04_01260	COG2022	thiamine diphosphate biosynthetic process
OB04_01261	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OB04_01262	COG0351	phosphomethylpyrimidine kinase
OB04_01263	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OB04_01274	COG0210	DNA helicase
OB04_01276	COG2153	protein acetylation
OB04_01277	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OB04_01278	COG2382	esterase
OB04_01279	COG0626	cystathionine gamma-synthase activity
OB04_01280	COG0626	cystathionine gamma-synthase activity
OB04_01281	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_01282	COG5505	Protein of unknown function (DUF819)
OB04_01286	COG5444	nuclease activity
OB04_01290	COG0457	Tetratricopeptide repeat
OB04_01291	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OB04_01292	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01294	COG3711	transcriptional antiterminator
OB04_01294	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_01295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_01295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OB04_01295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OB04_01296	COG1482	cell wall glycoprotein biosynthetic process
OB04_01298	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_01300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OB04_01303	COG0109	protoheme IX farnesyltransferase activity
OB04_01305	COG0726	polysaccharide deacetylase
OB04_01308	COG5504	Zn-dependent protease
OB04_01309	COG2205	protein histidine kinase activity
OB04_01311	COG3383	formate dehydrogenase (NAD+) activity
OB04_01312	COG2427	Protein of unknown function (DUF1641)
OB04_01314	COG1051	belongs to the nudix hydrolase family
OB04_01316	COG2124	cytochrome p450
OB04_01317	COG1819	glycosyl
OB04_01319	COG1587	Uroporphyrinogen-III synthase
OB04_01320	COG0390	transport system, permease component
OB04_01321	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OB04_01322	COG0697	spore germination
OB04_01323	COG4297	protein containing double-stranded beta helix domain
OB04_01325	COG1252	NADH dehydrogenase
OB04_01326	COG1904	glucuronate isomerase
OB04_01327	COG2211	Major facilitator Superfamily
OB04_01328	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
OB04_01329	COG1063	alcohol dehydrogenase
OB04_01330	COG1312	Catalyzes the dehydration of D-mannonate
OB04_01331	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01332	COG2271	Major facilitator Superfamily
OB04_01333	COG1609	Transcriptional regulator
OB04_01334	COG0246	Mannitol dehydrogenase
OB04_01335	COG2721	sulfolactate sulfo-lyase activity
OB04_01336	COG0730	response to heat
OB04_01337	COG2318	DinB family
OB04_01338	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OB04_01339	COG0457	Tetratricopeptide repeat
OB04_01341	COG2350	Protein conserved in bacteria
OB04_01342	COG1388	LysM domain
OB04_01342	COG3409	Peptidoglycan-binding domain 1 protein
OB04_01342	COG5632	N-Acetylmuramoyl-L-alanine amidase
OB04_01344	COG4195	phage-related replication protein
OB04_01345	COG3546	catalase activity
OB04_01346	COG2856	Zn peptidase
OB04_01347	COG1396	sequence-specific DNA binding
OB04_01349	COG1522	sequence-specific DNA binding
OB04_01350	COG1484	DNA-dependent DNA replication
OB04_01354	COG1595	DNA-templated transcription, initiation
OB04_01355	COG5484	DNA packaging
OB04_01355	COG3728	DNA packaging
OB04_01356	COG1783	phage Terminase large subunit
OB04_01357	COG5518	Phage portal protein
OB04_01358	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OB04_01359	COG4653	Phage capsid family
OB04_01367	COG5412	phage tail tape measure protein
OB04_01367	COG3953	SLT domain
OB04_01368	COG1652	LysM domain
OB04_01369	COG4193	domain, Protein
OB04_01371	COG3628	GPW Gp25 family protein
OB04_01372	COG3299	homolog of phage Mu protein gp47
OB04_01373	COG3778	Protein conserved in bacteria
OB04_01381	COG3409	Peptidoglycan-binding domain 1 protein
OB04_01381	COG5632	N-Acetylmuramoyl-L-alanine amidase
OB04_01384	COG0306	phosphate transporter
OB04_01385	COG1392	Phosphate transport regulator
OB04_01386	COG0531	amino acid
OB04_01387	COG0346	lactoylglutathione lyase activity
OB04_01388	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OB04_01389	COG0463	Glycosyl transferase, family 2
OB04_01391	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OB04_01392	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OB04_01393	COG2362	D-Aminopeptidase
OB04_01394	COG0601	transmembrane transport
OB04_01395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OB04_01396	COG0444	Belongs to the ABC transporter superfamily
OB04_01397	COG4166	transmembrane transport
OB04_01399	COG1619	proteins homologs of microcin C7 resistance protein MccF
OB04_01400	COG4948	Mandelate Racemase Muconate Lactonizing
OB04_01401	COG0791	NLP P60 protein
OB04_01402	COG4608	Belongs to the ABC transporter superfamily
OB04_01403	COG2706	6-phosphogluconolactonase activity
OB04_01404	COG1834	amidinotransferase
OB04_01405	COG1607	acyl-coa hydrolase
OB04_01406	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OB04_01406	COG1017	nitric oxide dioxygenase activity
OB04_01408	COG2323	membrane
OB04_01409	COG2318	DinB family
OB04_01410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_01411	COG2076	Multidrug Resistance protein
OB04_01412	COG2076	Multidrug Resistance protein
OB04_01413	COG0788	formyltetrahydrofolate deformylase activity
OB04_01414	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OB04_01415	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OB04_01417	COG1764	response to oxidative stress
OB04_01418	COG1846	Transcriptional regulator
OB04_01419	COG1764	response to oxidative stress
OB04_01420	COG0590	tRNA wobble adenosine to inosine editing
OB04_01421	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OB04_01422	COG1404	Belongs to the peptidase S8 family
OB04_01423	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_01424	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OB04_01425	COG1122	ATPase activity
OB04_01426	COG4721	ABC-type cobalt transport system, permease component
OB04_01428	COG0745	RESPONSE REGULATOR receiver
OB04_01429	COG5002	protein histidine kinase activity
OB04_01429	COG3850	Histidine kinase
OB04_01430	COG3212	peptidase
OB04_01431	COG3212	peptidase
OB04_01434	COG2239	Acts as a magnesium transporter
OB04_01435	COG0789	Transcriptional regulator
OB04_01438	COG1846	Transcriptional regulator
OB04_01439	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OB04_01440	COG0726	polysaccharide deacetylase
OB04_01441	COG1408	metallophosphoesterase
OB04_01443	COG0463	Glycosyl transferase, family 2
OB04_01444	COG3285	dna ligase
OB04_01444	COG1793	dna ligase
OB04_01445	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OB04_01446	COG5001	Diguanylate cyclase
OB04_01446	COG3300	MHYT domain
OB04_01447	COG0586	Pfam SNARE associated Golgi protein
OB04_01448	COG0861	Integral membrane protein TerC family
OB04_01449	COG1191	sigma factor activity
OB04_01453	COG0501	Belongs to the peptidase M48B family
OB04_01454	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OB04_01457	COG3594	Acyltransferase
OB04_01458	COG5002	protein histidine kinase activity
OB04_01459	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OB04_01461	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OB04_01462	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OB04_01463	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OB04_01464	COG0436	Aminotransferase
OB04_01465	COG1850	ribulose-bisphosphate carboxylase activity
OB04_01466	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OB04_01467	COG0235	Class ii aldolase
OB04_01468	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OB04_01469	COG3339	Conserved Protein
OB04_01472	COG3852	Histidine kinase
OB04_01473	COG1846	Transcriptional regulator
OB04_01474	COG1360	Flagellar Motor Protein
OB04_01475	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OB04_01476	COG0542	response to heat
OB04_01477	COG3949	Membrane
OB04_01478	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OB04_01479	COG0720	synthase
OB04_01480	COG0602	queuosine metabolic process
OB04_01481	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OB04_01482	COG1733	regulation of RNA biosynthetic process
OB04_01483	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01484	COG4641	Protein conserved in bacteria
OB04_01484	COG1388	LysM domain
OB04_01485	COG1388	LysM domain
OB04_01486	COG3858	chitin binding
OB04_01488	COG4873	Protein conserved in bacteria
OB04_01490	COG3773	Cell wall hydrolase
OB04_01491	COG2244	polysaccharide biosynthetic process
OB04_01492	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_01493	COG2217	Heavy metal translocating P-type atpase
OB04_01495	COG0006	proline dipeptidase activity
OB04_01496	COG1609	Transcriptional regulator
OB04_01497	COG3711	transcriptional antiterminator
OB04_01498	COG2190	(PTS) system
OB04_01498	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_01498	COG1263	PTS System
OB04_01499	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_01500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OB04_01502	COG1533	DNA photolyase activity
OB04_01503	COG0456	acetyltransferase
OB04_01504	COG0840	transmembrane signaling receptor activity
OB04_01505	COG2084	Dehydrogenase
OB04_01506	COG2340	Cysteine-rich secretory protein family
OB04_01507	COG0768	penicillin binding
OB04_01508	COG4191	Histidine kinase
OB04_01509	COG0436	Aminotransferase
OB04_01511	COG0835	chemotaxis
OB04_01511	COG0784	Response regulator, receiver
OB04_01513	COG2814	Major facilitator Superfamily
OB04_01514	COG1376	ErfK ybiS ycfS ynhG family protein
OB04_01515	COG1408	metallophosphoesterase
OB04_01516	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01517	COG2200	EAL domain
OB04_01518	COG4703	Protein of unknown function (DUF1797)
OB04_01519	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
OB04_01521	COG0517	IMP dehydrogenase activity
OB04_01522	COG0583	DNA-binding transcription factor activity
OB04_01523	COG0716	FMN binding
OB04_01525	COG0716	FMN binding
OB04_01526	COG2171	N-acyltransferase activity
OB04_01527	COG1473	amidohydrolase
OB04_01529	COG0668	transmembrane transport
OB04_01530	COG0450	alkyl hydroperoxide reductase
OB04_01531	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_01534	COG0746	molybdenum cofactor guanylyltransferase activity
OB04_01535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OB04_01536	COG0303	'Molybdopterin
OB04_01537	COG1763	Mo-molybdopterin cofactor biosynthetic process
OB04_01538	COG0314	molybdopterin synthase activity
OB04_01539	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OB04_01540	COG1132	(ABC) transporter
OB04_01541	COG1132	(ABC) transporter
OB04_01543	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OB04_01544	COG1136	(ABC) transporter
OB04_01545	COG0577	efflux transmembrane transporter activity
OB04_01546	COG1349	DNA-binding transcription factor activity
OB04_01547	COG1105	Belongs to the carbohydrate kinase PfkB family
OB04_01548	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_01548	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OB04_01548	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OB04_01549	COG0681	Belongs to the peptidase S26 family
OB04_01551	COG0488	(ABC) transporter
OB04_01552	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OB04_01553	COG2309	aminopeptidase activity
OB04_01555	COG1077	Cell shape determining protein MreB Mrl
OB04_01556	COG2002	toxin-antitoxin pair type II binding
OB04_01557	COG3852	Histidine kinase
OB04_01558	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
OB04_01558	COG2105	PFAM AIG2 family protein
OB04_01559	COG0569	domain protein
OB04_01560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OB04_01561	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OB04_01563	COG0561	phosphatase activity
OB04_01564	COG0242	peptide deformylase activity
OB04_01566	COG0497	DNA recombination
OB04_01567	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OB04_01568	COG0022	dehydrogenase e1 component
OB04_01569	COG0508	dehydrogenase complex catalyzes the overall conversion of
OB04_01570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OB04_01571	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_01573	COG1982	Orn Lys Arg decarboxylase major
OB04_01574	COG4476	Belongs to the UPF0223 family
OB04_01575	COG4493	Belongs to the UPF0637 family
OB04_01577	COG0483	inositol monophosphate 1-phosphatase activity
OB04_01579	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OB04_01583	COG1595	DNA-templated transcription, initiation
OB04_01589	COG4896	Protein conserved in bacteria
OB04_01591	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OB04_01592	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OB04_01593	COG2066	Belongs to the glutaminase family
OB04_01594	COG4838	Belongs to the UPF0358 family
OB04_01595	COG0772	Belongs to the SEDS family
OB04_01596	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OB04_01597	COG1612	heme a metabolic process
OB04_01598	COG0109	protoheme IX farnesyltransferase activity
OB04_01599	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OB04_01599	COG2010	Cytochrome c
OB04_01600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OB04_01601	COG1845	cytochrome c oxidase, subunit III
OB04_01602	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OB04_01603	COG3336	cytochrome c oxidase
OB04_01605	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OB04_01606	COG2340	Cysteine-rich secretory protein family
OB04_01609	COG3679	Belongs to the UPF0342 family
OB04_01610	COG4471	UPF0298 protein
OB04_01611	COG0742	ribosomal rna small subunit methyltransferase
OB04_01612	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OB04_01613	COG3314	Sporulation integral membrane protein YlbJ
OB04_01614	COG1752	Esterase of the alpha-beta hydrolase superfamily
OB04_01615	COG3480	Lon protease (S16) C-terminal proteolytic domain
OB04_01616	COG1323	Belongs to the UPF0348 family
OB04_01618	COG1399	metal-binding, possibly nucleic acid-binding protein
OB04_01619	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OB04_01621	COG0454	-acetyltransferase
OB04_01622	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OB04_01623	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OB04_01624	COG2001	Belongs to the MraZ family
OB04_01625	COG0275	rRNA processing
OB04_01626	COG4839	cell division protein FtsL
OB04_01628	COG0768	penicillin binding
OB04_01629	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OB04_01630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OB04_01631	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OB04_01632	COG0772	Belongs to the SEDS family
OB04_01633	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OB04_01634	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OB04_01635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OB04_01636	COG3879	Bacterial protein of unknown function (DUF881)
OB04_01637	COG3879	Bacterial protein of unknown function (DUF881)
OB04_01638	COG3856	small basic protein
OB04_01639	COG0849	cell division
OB04_01640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OB04_01641	COG4412	M6 family metalloprotease domain protein
OB04_01641	COG1404	Belongs to the peptidase S8 family
OB04_01643	COG1191	sigma factor activity
OB04_01644	COG1191	sigma factor activity
OB04_01645	COG1119	ATPase activity
OB04_01646	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OB04_01647	COG1873	PFAM PRC-barrel domain
OB04_01649	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OB04_01650	COG1799	cell septum assembly
OB04_01651	COG0762	integral membrane protein
OB04_01652	COG2302	S4 RNA-binding domain
OB04_01653	COG3599	regulation of cell shape
OB04_01654	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OB04_01655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OB04_01656	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OB04_01657	COG0564	pseudouridine synthase activity
OB04_01658	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OB04_01659	COG2233	PERMEase
OB04_01660	COG0540	Belongs to the ATCase OTCase family
OB04_01661	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OB04_01662	COG0505	Belongs to the CarA family
OB04_01663	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OB04_01664	COG0543	2 iron, 2 sulfur cluster binding
OB04_01665	COG0167	dihydroorotate dehydrogenase activity
OB04_01666	COG0284	orotidine-5'-phosphate decarboxylase activity
OB04_01667	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OB04_01669	COG0175	sulfate reduction
OB04_01670	COG0306	phosphate transporter
OB04_01671	COG2046	Belongs to the sulfate adenylyltransferase family
OB04_01672	COG0529	Catalyzes the synthesis of activated sulfate
OB04_01673	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OB04_01674	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
OB04_01675	COG1648	precorrin-2 dehydrogenase activity
OB04_01677	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OB04_01678	COG1561	YicC-like family, N-terminal region
OB04_01679	COG2052	Domain of unknown function (DUF370)
OB04_01680	COG0194	GDP metabolic process
OB04_01681	COG1758	RNA polymerase activity
OB04_01682	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OB04_01683	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OB04_01684	COG0242	peptide deformylase activity
OB04_01685	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OB04_01686	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OB04_01686	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OB04_01687	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OB04_01688	COG0631	protein serine/threonine phosphatase activity
OB04_01689	COG0515	serine threonine protein kinase
OB04_01689	COG2815	serine threonine protein kinase
OB04_01690	COG1162	GTPase activity
OB04_01691	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OB04_01692	COG1564	THIamine pyrophosphokinase
OB04_01693	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OB04_01694	COG1302	Protein conserved in bacteria
OB04_01695	COG1461	Dihydroxyacetone kinase
OB04_01696	COG1760	l-serine dehydratase
OB04_01697	COG1760	l-serine dehydratase
OB04_01698	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OB04_01699	COG2050	protein possibly involved in aromatic compounds catabolism
OB04_01699	COG1349	DNA-binding transcription factor activity
OB04_01700	COG0416	fatty acid biosynthetic process
OB04_01701	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OB04_01702	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01703	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_01704	COG0571	ribonuclease III activity
OB04_01705	COG1196	nuclear chromosome segregation
OB04_01706	COG0552	protein localization to endoplasmic reticulum
OB04_01708	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OB04_01709	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OB04_01710	COG0228	four-way junction DNA binding
OB04_01711	COG1837	Belongs to the UPF0109 family
OB04_01713	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OB04_01714	COG0336	Belongs to the RNA methyltransferase TrmD family
OB04_01715	COG0335	large ribosomal subunit rRNA binding
OB04_01716	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OB04_01717	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OB04_01719	COG2257	FlhB HrpN YscU SpaS Family
OB04_01720	COG0045	succinate-CoA ligase (ADP-forming) activity
OB04_01721	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OB04_01722	COG0758	DNA mediated transformation
OB04_01723	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OB04_01724	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OB04_01725	COG4974	Belongs to the 'phage' integrase family
OB04_01726	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OB04_01727	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OB04_01728	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OB04_01729	COG1815	bacterial-type flagellum-dependent cell motility
OB04_01730	COG1558	bacterial-type flagellum-dependent cell motility
OB04_01731	COG1677	Flagellar hook-basal body complex protein FliE
OB04_01732	COG1766	The M ring may be actively involved in energy transduction
OB04_01733	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OB04_01734	COG1317	bacterial-type flagellum organization
OB04_01735	COG1157	protein secretion by the type III secretion system
OB04_01736	COG2882	bacterial-type flagellum organization
OB04_01737	COG3334	PFAM MgtE intracellular
OB04_01738	COG3144	bacterial-type flagellum assembly
OB04_01739	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OB04_01740	COG4786	Flagellar basal body rod
OB04_01741	COG1580	Controls the rotational direction of flagella during chemotaxis
OB04_01742	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OB04_01743	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OB04_01743	COG1776	CheC inhibitor of MCP methylation
OB04_01744	COG2201	protein-glutamate methylesterase activity
OB04_01745	COG3190	flagellar
OB04_01746	COG1338	Plays a role in the flagellum-specific transport system
OB04_01747	COG1987	bacterial-type flagellum assembly
OB04_01748	COG1684	flagellar biosynthetic protein fliR
OB04_01749	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OB04_01750	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OB04_01751	COG1419	protein localization to endoplasmic reticulum
OB04_01752	COG0455	bacterial-type flagellum organization
OB04_01753	COG2201	protein-glutamate methylesterase activity
OB04_01754	COG0643	Histidine kinase
OB04_01754	COG2198	Histidine kinase
OB04_01755	COG0835	chemotaxis
OB04_01756	COG1776	CheC inhibitor of MCP methylation
OB04_01757	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OB04_01758	COG1191	sigma factor activity
OB04_01760	COG0052	Belongs to the universal ribosomal protein uS2 family
OB04_01761	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OB04_01762	COG0528	UMP kinase activity
OB04_01763	COG0233	cytoplasmic translational termination
OB04_01764	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OB04_01765	COG4589	Belongs to the CDS family
OB04_01766	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OB04_01767	COG0750	zinc metalloprotease
OB04_01768	COG0442	prolyl-tRNA aminoacylation
OB04_01769	COG2176	DNA-directed DNA polymerase activity
OB04_01770	COG0779	Required for maturation of 30S ribosomal subunits
OB04_01771	COG0195	Participates in both transcription termination and antitermination
OB04_01772	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OB04_01773	COG1358	cellular component organization or biogenesis
OB04_01774	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OB04_01775	COG1550	Protein conserved in bacteria
OB04_01776	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OB04_01777	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OB04_01778	COG0196	riboflavin kinase activity
OB04_01779	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OB04_01780	COG1185	polyribonucleotide nucleotidyltransferase activity
OB04_01781	COG0726	polysaccharide deacetylase
OB04_01782	COG0612	Peptidase, M16
OB04_01783	COG1873	PFAM PRC-barrel domain
OB04_01784	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OB04_01785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OB04_01786	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OB04_01787	COG0527	aspartate kinase activity
OB04_01788	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OB04_01789	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OB04_01790	COG0740	serine-type endopeptidase activity
OB04_01792	COG4980	gas vesicle protein
OB04_01792	COG1674	ftsk spoiiie
OB04_01793	COG2188	Transcriptional regulator
OB04_01794	COG2814	Major facilitator Superfamily
OB04_01795	COG0612	Peptidase, M16
OB04_01796	COG0612	Peptidase, M16
OB04_01797	COG0300	oxidoreductase activity
OB04_01800	COG1426	Protein conserved in bacteria
OB04_01801	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OB04_01802	COG1546	Belongs to the CinA family
OB04_01802	COG1058	Belongs to the CinA family
OB04_01803	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OB04_01804	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OB04_01805	COG1418	mRNA catabolic process
OB04_01806	COG1692	metallophosphoesterase
OB04_01807	COG2359	stage V sporulation protein S
OB04_01808	COG1063	alcohol dehydrogenase
OB04_01809	COG0156	8-amino-7-oxononanoate synthase activity
OB04_01810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OB04_01811	COG4550	Control of competence regulator ComK, YlbF/YmcA
OB04_01813	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OB04_01814	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OB04_01817	COG3226	Transcriptional regulator
OB04_01818	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_01819	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OB04_01821	COG3321	synthase
OB04_01822	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OB04_01822	COG2070	2-Nitropropane dioxygenase
OB04_01823	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_01824	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OB04_01825	COG3425	synthase
OB04_01826	COG1024	Enoyl-CoA hydratase
OB04_01827	COG1024	Enoyl-CoA hydratase
OB04_01828	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_01828	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01828	COG0300	oxidoreductase activity
OB04_01828	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_01828	COG3321	synthase
OB04_01829	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_01829	COG3321	synthase
OB04_01829	COG0300	oxidoreductase activity
OB04_01829	COG4221	oxidoreductase activity
OB04_01830	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_01830	COG3321	synthase
OB04_01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_01830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OB04_01831	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_01831	COG3321	synthase
OB04_01831	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_01831	COG4221	oxidoreductase activity
OB04_01832	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OB04_01832	COG3321	synthase
OB04_01832	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OB04_01832	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_01833	COG2124	cytochrome p450
OB04_01835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_01836	COG1404	Belongs to the peptidase S8 family
OB04_01838	COG4195	phage-related replication protein
OB04_01839	COG1764	response to oxidative stress
OB04_01840	COG2076	Multidrug Resistance protein
OB04_01841	COG2076	Multidrug Resistance protein
OB04_01844	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OB04_01845	COG1923	regulation of RNA biosynthetic process
OB04_01848	COG1780	Probably involved in ribonucleotide reductase function
OB04_01849	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OB04_01850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OB04_01851	COG4112	unkown
OB04_01852	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_01853	COG0464	growth
OB04_01854	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OB04_01855	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OB04_01856	COG0789	Transcriptional regulator
OB04_01857	COG0174	glutamine synthetase
OB04_01862	COG0463	Glycosyl transferase, family 2
OB04_01864	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_01868	COG3655	Transcriptional regulator
OB04_01872	COG0135	phosphoribosylanthranilate isomerase activity
OB04_01874	COG2211	Major facilitator Superfamily
OB04_01875	COG3507	Belongs to the glycosyl hydrolase 43 family
OB04_01876	COG1940	carbohydrate kinase activity
OB04_01877	COG2115	Belongs to the xylose isomerase family
OB04_01878	COG1070	Carbohydrate kinase
OB04_01879	COG1525	nuclease
OB04_01880	COG2814	Major facilitator Superfamily
OB04_01881	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OB04_01883	COG0756	dUTP diphosphatase activity
OB04_01887	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OB04_01893	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OB04_01895	COG3832	glyoxalase III activity
OB04_01899	COG0697	spore germination
OB04_01900	COG0531	amino acid
OB04_01906	COG4195	phage-related replication protein
OB04_01908	COG0346	lactoylglutathione lyase activity
OB04_01909	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OB04_01910	COG1388	LysM domain
OB04_01911	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OB04_01912	COG4224	UPF0291 protein
OB04_01913	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OB04_01915	COG3763	UPF0154 protein
OB04_01917	COG0785	Cytochrome C biogenesis protein
OB04_01918	COG2201	protein-glutamate methylesterase activity
OB04_01919	COG4846	Membrane protein involved in cytochrome C biogenesis
OB04_01921	COG0071	Belongs to the small heat shock protein (HSP20) family
OB04_01924	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OB04_01925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_01929	COG0824	Thioesterase
OB04_01931	COG4841	protein insertion into membrane
OB04_01932	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OB04_01933	COG1832	CoA-binding protein
OB04_01934	COG0187	DNA topoisomerase II activity
OB04_01935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OB04_01938	COG1115	amino acid carrier protein
OB04_01939	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OB04_01941	COG5520	Belongs to the glycosyl hydrolase 30 family
OB04_01942	COG3507	Belongs to the glycosyl hydrolase 43 family
OB04_01943	COG2246	polysaccharide biosynthetic process
OB04_01944	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OB04_01945	COG0586	Pfam SNARE associated Golgi protein
OB04_01946	COG2404	hydrolase activity, acting on ester bonds
OB04_01947	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OB04_01948	COG1024	Enoyl-CoA hydratase
OB04_01949	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OB04_01950	COG0511	ligase activity, forming carbon-carbon bonds
OB04_01951	COG0439	Biotin carboxylase
OB04_01952	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_01953	COG1960	acyl-CoA dehydrogenase activity
OB04_01955	COG1649	PFAM Uncharacterised BCR, COG1649
OB04_01957	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OB04_01957	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_01958	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_01959	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_01960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_01961	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_01962	COG2027	D-alanyl-D-alanine carboxypeptidase
OB04_01963	COG2017	converts alpha-aldose to the beta-anomer
OB04_01964	COG0534	Mate efflux family protein
OB04_01967	COG0582	viral genome integration into host DNA
OB04_01968	COG0166	Belongs to the GPI family
OB04_01969	COG0405	Gamma-glutamyltransferase
OB04_01970	COG0583	DNA-binding transcription factor activity
OB04_01971	COG0604	alcohol dehydrogenase
OB04_01972	COG0493	'glutamate synthase
OB04_01973	COG0070	glutamate synthase
OB04_01973	COG0069	glutamate synthase activity
OB04_01973	COG0067	glutamate synthase
OB04_01974	COG0583	DNA-binding transcription factor activity
OB04_01975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OB04_01976	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OB04_01978	COG0300	oxidoreductase activity
OB04_01979	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OB04_01981	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_01982	COG2814	Major facilitator Superfamily
OB04_01983	COG1070	Carbohydrate kinase
OB04_01984	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OB04_01985	COG0243	molybdopterin cofactor binding
OB04_01990	COG0840	transmembrane signaling receptor activity
OB04_01990	COG5278	phosphoserine phosphatase activity
OB04_01991	COG2368	4-hydroxyphenylacetate
OB04_01992	COG4305	rare lipoprotein A
OB04_01993	COG3619	membrane
OB04_01994	COG3866	Pectate lyase
OB04_01995	COG2135	peptidase activity
OB04_01997	COG2140	Oxalate decarboxylase
OB04_01999	COG0456	acetyltransferase
OB04_02003	COG2720	vancomycin resistance protein
OB04_02005	COG3655	Transcriptional regulator
OB04_02006	COG3739	integral membrane protein
OB04_02007	COG0583	DNA-binding transcription factor activity
OB04_02008	COG0697	spore germination
OB04_02010	COG0693	protein deglycase activity
OB04_02011	COG2367	Beta-lactamase
OB04_02015	COG0574	Belongs to the PEP-utilizing enzyme family
OB04_02015	COG3848	Pyruvate phosphate dikinase
OB04_02016	COG0726	polysaccharide deacetylase
OB04_02017	COG2314	TM2 domain
OB04_02018	COG1396	sequence-specific DNA binding
OB04_02020	COG2135	peptidase activity
OB04_02021	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OB04_02024	COG2723	6-phospho-beta-galactosidase activity
OB04_02027	COG0395	ABC-type sugar transport system, permease component
OB04_02028	COG1175	transmembrane transport
OB04_02030	COG1940	carbohydrate kinase activity
OB04_02032	COG5444	nuclease activity
OB04_02033	COG4282	regulation of fungal-type cell wall biogenesis
OB04_02034	COG1231	oxidoreductase activity
OB04_02035	COG5434	Belongs to the glycosyl hydrolase 28 family
OB04_02036	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OB04_02037	COG2207	Transcriptional regulator
OB04_02037	COG0662	Cupin 2, conserved barrel domain protein
OB04_02038	COG0456	acetyltransferase
OB04_02039	COG1309	transcriptional regulator
OB04_02040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_02041	COG3708	Transcriptional regulator
OB04_02042	COG2378	regulation of single-species biofilm formation
OB04_02044	COG0640	Transcriptional regulator
OB04_02045	COG0741	lytic transglycosylase activity
OB04_02046	COG2322	membrane
OB04_02049	COG1619	proteins homologs of microcin C7 resistance protein MccF
OB04_02050	COG3239	Fatty acid desaturase
OB04_02051	COG4585	Histidine kinase
OB04_02052	COG2197	response regulator
OB04_02053	COG3584	3D domain protein
OB04_02053	COG1388	LysM domain
OB04_02054	COG0514	ATP-dependent DNA helicase (RecQ)
OB04_02055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OB04_02056	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OB04_02059	COG0071	Belongs to the small heat shock protein (HSP20) family
OB04_02064	COG1012	belongs to the aldehyde dehydrogenase family
OB04_02065	COG1657	PFAM Prenyltransferase squalene oxidase
OB04_02066	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OB04_02067	COG0733	neurotransmitter:sodium symporter activity
OB04_02068	COG0385	Bile acid
OB04_02069	COG0508	dehydrogenase complex catalyzes the overall conversion of
OB04_02070	COG0567	Dehydrogenase, E1 component
OB04_02071	COG4548	von Willebrand factor, type A
OB04_02072	COG0714	Associated with various cellular activities
OB04_02073	COG2032	superoxide dismutase activity
OB04_02074	COG1388	LysM domain
OB04_02074	COG0791	NLP P60 protein
OB04_02075	COG1819	glycosyl
OB04_02076	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OB04_02078	COG0534	Mate efflux family protein
OB04_02079	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_02080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OB04_02081	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OB04_02083	COG2962	Rard protein
OB04_02086	COG2610	gluconate transmembrane transporter activity
OB04_02087	COG1942	4-Oxalocrotonate Tautomerase
OB04_02088	COG1733	regulation of RNA biosynthetic process
OB04_02089	COG0778	Nitroreductase
OB04_02090	COG0400	carboxylic ester hydrolase activity
OB04_02091	COG0346	lactoylglutathione lyase activity
OB04_02093	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OB04_02094	COG3409	Peptidoglycan-binding domain 1 protein
OB04_02094	COG0793	Belongs to the peptidase S41A family
OB04_02095	COG2226	methyltransferase
OB04_02097	COG1876	peptidase activity
OB04_02098	COG0813	purine-nucleoside phosphorylase activity
OB04_02101	COG0671	phosphoesterase, PA-phosphatase related
OB04_02105	COG4479	Belongs to the UPF0346 family
OB04_02107	COG1509	lysine 2,3-aminomutase activity
OB04_02108	COG0456	acetyltransferase
OB04_02109	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OB04_02110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OB04_02111	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OB04_02112	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OB04_02114	COG0456	acetyltransferase
OB04_02115	COG0463	Glycosyl transferase, family 2
OB04_02118	COG4641	Protein conserved in bacteria
OB04_02119	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
OB04_02120	COG1086	Polysaccharide biosynthesis protein
OB04_02121	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OB04_02122	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OB04_02123	COG1846	Transcriptional regulator
OB04_02124	COG0534	Mate efflux family protein
OB04_02126	COG4698	Protein conserved in bacteria
OB04_02127	COG2755	lipolytic protein G-D-S-L family
OB04_02128	COG1999	signal sequence binding
OB04_02130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OB04_02131	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OB04_02132	COG1272	protein, Hemolysin III
OB04_02133	COG0204	Acyl-transferase
OB04_02134	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OB04_02135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OB04_02136	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OB04_02138	COG2136	Putative SAM-dependent methyltransferase
OB04_02138	COG2521	methyltransferase
OB04_02140	COG0129	dihydroxy-acid dehydratase activity
OB04_02141	COG1413	lyase activity
OB04_02142	COG1418	mRNA catabolic process
OB04_02143	COG0386	Belongs to the glutathione peroxidase family
OB04_02144	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OB04_02146	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OB04_02147	COG1278	Cold shock
OB04_02151	COG0328	RNA-DNA hybrid ribonuclease activity
OB04_02152	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OB04_02153	COG0328	RNA-DNA hybrid ribonuclease activity
OB04_02155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OB04_02158	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OB04_02159	COG1755	Isoprenylcysteine carboxyl methyltransferase
OB04_02160	COG3424	synthase
OB04_02161	COG2233	PERMEase
OB04_02162	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OB04_02163	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OB04_02165	COG0800	Aldolase
OB04_02166	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OB04_02167	COG1609	Transcriptional regulator
OB04_02168	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OB04_02169	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_02170	COG1199	ATP-dependent helicase activity
OB04_02172	COG0116	Belongs to the methyltransferase superfamily
OB04_02174	COG4474	Belongs to the UPF0398 family
OB04_02175	COG3359	exonuclease
OB04_02176	COG1111	helicase
OB04_02176	COG1205	dead DEAH box helicase
OB04_02177	COG2190	(PTS) system
OB04_02178	COG0071	Belongs to the small heat shock protein (HSP20) family
OB04_02185	COG3331	DNA recombination
OB04_02186	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OB04_02186	COG4499	WXG100 protein secretion system (Wss), protein YukC
OB04_02188	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OB04_02189	COG3935	DnaD domain protein
OB04_02190	COG0017	Asparaginyl-tRNA synthetase
OB04_02191	COG0436	Aminotransferase
OB04_02192	COG5353	protein conserved in bacteria
OB04_02194	COG1199	ATP-dependent helicase activity
OB04_02194	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OB04_02195	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OB04_02196	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OB04_02197	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OB04_02198	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OB04_02198	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OB04_02199	COG0617	tRNA 3'-terminal CCA addition
OB04_02200	COG0438	transferase activity, transferring glycosyl groups
OB04_02201	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OB04_02202	COG1803	Methylglyoxal synthase
OB04_02203	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OB04_02204	COG1694	Mazg nucleotide pyrophosphohydrolase
OB04_02205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_02207	COG4347	Protein of unknown function (DUF1405)
OB04_02208	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OB04_02208	COG2010	Cytochrome c
OB04_02209	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OB04_02210	COG0723	plastoquinol--plastocyanin reductase activity
OB04_02212	COG5582	Belongs to the UPF0302 family
OB04_02213	COG0457	Tetratricopeptide repeat
OB04_02214	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OB04_02215	COG0287	Prephenate dehydrogenase
OB04_02217	COG0159	tryptophan synthase activity
OB04_02218	COG0133	tryptophan synthase activity
OB04_02219	COG0135	phosphoribosylanthranilate isomerase activity
OB04_02221	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OB04_02222	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OB04_02223	COG4401	Chorismate mutase type I
OB04_02224	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OB04_02225	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OB04_02226	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OB04_02227	COG0105	UTP biosynthetic process
OB04_02228	COG0142	geranyltranstransferase activity
OB04_02229	COG2226	methyltransferase
OB04_02230	COG0142	geranyltranstransferase activity
OB04_02232	COG0302	gtp cyclohydrolase
OB04_02233	COG0776	regulation of translation
OB04_02234	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OB04_02237	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OB04_02238	COG1160	GTP binding
OB04_02243	COG1304	FMN binding
OB04_02244	COG0539	negative regulation of cytoplasmic translation
OB04_02245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OB04_02247	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
OB04_02248	COG2959	enzyme of heme biosynthesis
OB04_02249	COG3409	Peptidoglycan-binding domain 1 protein
OB04_02249	COG3773	Cell wall hydrolase
OB04_02250	COG2339	peptidase activity
OB04_02251	COG0492	ferredoxin-NADP+ reductase activity
OB04_02252	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OB04_02253	COG4862	establishment of competence for transformation
OB04_02254	COG1408	metallophosphoesterase
OB04_02256	COG1388	LysM domain
OB04_02257	COG1266	CAAX protease self-immunity
OB04_02258	COG0514	ATP-dependent DNA helicase (RecQ)
OB04_02259	COG4955	Helix-turn-helix domain
OB04_02260	COG1141	Ferredoxin
OB04_02261	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OB04_02262	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OB04_02263	COG0710	3-dehydroquinate dehydratase activity
OB04_02265	COG1595	DNA-templated transcription, initiation
OB04_02266	COG5002	protein histidine kinase activity
OB04_02267	COG0745	RESPONSE REGULATOR receiver
OB04_02268	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OB04_02269	COG1333	cytochrome c biogenesis protein
OB04_02270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_02271	COG1187	pseudouridine synthase activity
OB04_02272	COG0700	Nucleoside recognition
OB04_02273	COG2715	membrane protein required for spore maturation
OB04_02274	COG1686	Belongs to the peptidase S11 family
OB04_02276	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OB04_02277	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OB04_02278	COG1547	Domain of unknown function (DUF309)
OB04_02279	COG0456	acetyltransferase
OB04_02280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OB04_02281	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OB04_02281	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OB04_02282	COG0307	riboflavin synthase, alpha
OB04_02283	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OB04_02283	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OB04_02285	COG0681	Belongs to the peptidase S26 family
OB04_02286	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
OB04_02289	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OB04_02290	COG4086	secreted protein
OB04_02291	COG0019	diaminopimelate decarboxylase activity
OB04_02292	COG0697	spore germination
OB04_02295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OB04_02299	COG1191	sigma factor activity
OB04_02300	COG2172	sigma factor antagonist activity
OB04_02301	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_02302	COG1686	Belongs to the peptidase S11 family
OB04_02303	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OB04_02304	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OB04_02305	COG4974	Belongs to the 'phage' integrase family
OB04_02307	COG0735	belongs to the Fur family
OB04_02308	COG1300	Membrane
OB04_02310	COG0281	malic enzyme
OB04_02311	COG1757	Na H antiporter
OB04_02312	COG1027	Aspartate ammonia-lyase
OB04_02313	COG0252	asparaginase activity
OB04_02314	COG1396	sequence-specific DNA binding
OB04_02315	COG1379	DNA repair
OB04_02316	COG0494	nUDIX hydrolase
OB04_02318	COG0667	Aldo Keto reductase
OB04_02320	COG1073	alpha beta
OB04_02322	COG4918	Iron-sulphur cluster biosynthesis
OB04_02323	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OB04_02323	COG0456	acetyltransferase
OB04_02324	COG2329	Antibiotic biosynthesis monooxygenase
OB04_02325	COG0456	acetyltransferase
OB04_02327	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OB04_02332	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_02333	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OB04_02337	COG0492	ferredoxin-NADP+ reductase activity
OB04_02338	COG3118	belongs to the thioredoxin family
OB04_02340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_02342	COG0509	glycine decarboxylation via glycine cleavage system
OB04_02344	COG1309	transcriptional regulator
OB04_02345	COG1609	Transcriptional regulator
OB04_02347	COG1175	transmembrane transport
OB04_02348	COG0395	ABC-type sugar transport system, permease component
OB04_02350	COG1621	beta-fructofuranosidase activity
OB04_02352	COG0110	maltose O-acetyltransferase activity
OB04_02360	COG0210	DNA helicase
OB04_02362	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OB04_02368	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OB04_02370	COG2211	Major facilitator Superfamily
OB04_02372	COG0346	lactoylglutathione lyase activity
OB04_02373	COG1072	(Pantothenic acid kinase))
OB04_02374	COG3048	D-serine ammonia-lyase activity
OB04_02375	COG0300	oxidoreductase activity
OB04_02376	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_02377	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OB04_02378	COG4187	Peptidase family M20/M25/M40
OB04_02379	COG1902	pentaerythritol trinitrate reductase activity
OB04_02380	COG0596	Alpha beta hydrolase
OB04_02382	COG1234	tRNA 3'-trailer cleavage
OB04_02383	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OB04_02384	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OB04_02385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OB04_02387	COG0706	membrane insertase activity
OB04_02388	COG3361	conserved protein (COG2071)
OB04_02389	COG2195	Cleaves the N-terminal amino acid of tripeptides
OB04_02390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OB04_02391	COG0346	lactoylglutathione lyase activity
OB04_02393	COG1376	ErfK ybiS ycfS ynhG family protein
OB04_02394	COG4129	membrane
OB04_02395	COG1126	abc transporter atp-binding protein
OB04_02396	COG0765	amino acid transport
OB04_02397	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_02399	COG1597	lipid kinase activity
OB04_02400	COG2814	Major facilitator Superfamily
OB04_02401	COG4978	Transcriptional regulator
OB04_02401	COG0789	Transcriptional regulator
OB04_02402	COG0508	dehydrogenase complex catalyzes the overall conversion of
OB04_02403	COG0022	dehydrogenase e1 component
OB04_02404	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OB04_02405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OB04_02406	COG3426	butyrate kinase activity
OB04_02407	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OB04_02408	COG0280	phosphate acetyltransferase
OB04_02409	COG3290	protein histidine kinase activity
OB04_02409	COG3829	transcription factor binding
OB04_02410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OB04_02411	COG2079	MmgE PrpD family protein
OB04_02412	COG0372	Belongs to the citrate synthase family
OB04_02413	COG1960	acyl-CoA dehydrogenase activity
OB04_02414	COG1250	3-hydroxyacyl-CoA dehydrogenase
OB04_02415	COG0183	Belongs to the thiolase family
OB04_02416	COG0584	glycerophosphoryl diester phosphodiesterase
OB04_02417	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_02419	COG1902	pentaerythritol trinitrate reductase activity
OB04_02420	COG0745	RESPONSE REGULATOR receiver
OB04_02421	COG0750	zinc metalloprotease
OB04_02422	COG0497	DNA recombination
OB04_02423	COG1438	arginine binding
OB04_02424	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OB04_02425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OB04_02426	COG0142	geranyltranstransferase activity
OB04_02427	COG1722	exodeoxyribonuclease VII activity
OB04_02428	COG1570	exodeoxyribonuclease VII activity
OB04_02429	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OB04_02430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OB04_02431	COG1302	Protein conserved in bacteria
OB04_02432	COG0439	Biotin carboxylase
OB04_02433	COG0511	ligase activity, forming carbon-carbon bonds
OB04_02441	COG3854	ATPases associated with a variety of cellular activities
OB04_02443	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OB04_02444	COG0006	proline dipeptidase activity
OB04_02445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OB04_02447	COG3872	metal-dependent enzyme
OB04_02449	COG1752	Esterase of the alpha-beta hydrolase superfamily
OB04_02450	COG1321	iron dependent repressor
OB04_02451	COG0095	Lipoate-protein ligase
OB04_02452	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OB04_02453	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OB04_02454	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OB04_02455	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OB04_02456	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OB04_02459	COG1396	sequence-specific DNA binding
OB04_02461	COG0681	Belongs to the peptidase S26 family
OB04_02466	COG4940	Competence protein ComGF
OB04_02468	COG4970	Tfp pilus assembly protein FimT
OB04_02469	COG4537	Required for transformation and DNA binding
OB04_02470	COG1459	type II secretion system
OB04_02471	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OB04_02474	COG0598	Magnesium transport protein CorA
OB04_02475	COG1253	flavin adenine dinucleotide binding
OB04_02476	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_02478	COG1393	Belongs to the ArsC family
OB04_02480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_02482	COG0011	TIGRFAM Protein of
OB04_02484	COG2866	Carboxypeptidase
OB04_02485	COG1368	sulfuric ester hydrolase activity
OB04_02486	COG1940	carbohydrate kinase activity
OB04_02487	COG4483	Protein conserved in bacteria
OB04_02488	COG0705	Rhomboid family
OB04_02488	COG0457	Tetratricopeptide repeat
OB04_02490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OB04_02491	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OB04_02492	COG0438	transferase activity, transferring glycosyl groups
OB04_02495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OB04_02496	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OB04_02497	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OB04_02498	COG0581	inorganic phosphate transmembrane transporter activity
OB04_02499	COG0573	inorganic phosphate transmembrane transporter activity
OB04_02500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OB04_02502	COG0477	Major facilitator Superfamily
OB04_02503	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OB04_02504	COG2839	Protein conserved in bacteria
OB04_02505	COG5521	maltodextrose utilization protein MalA
OB04_02506	COG1388	LysM domain
OB04_02507	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OB04_02508	COG4709	membrane
OB04_02509	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
OB04_02510	COG0735	belongs to the Fur family
OB04_02511	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_02513	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OB04_02514	COG0513	Belongs to the DEAD box helicase family
OB04_02516	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OB04_02517	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OB04_02518	COG2384	SAM-dependent methyltransferase
OB04_02519	COG2010	Cytochrome c
OB04_02520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OB04_02521	COG0358	DNA primase activity
OB04_02522	COG1671	Belongs to the UPF0178 family
OB04_02523	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OB04_02524	COG0517	IMP dehydrogenase activity
OB04_02525	COG0751	glycine-tRNA ligase activity
OB04_02526	COG0752	glycyl-tRNA synthetase alpha subunit
OB04_02527	COG1381	Involved in DNA repair and RecF pathway recombination
OB04_02529	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OB04_02530	COG0295	cytidine deaminase activity
OB04_02531	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OB04_02532	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OB04_02533	COG1480	7TM receptor with intracellular HD hydrolase
OB04_02535	COG1702	phosphate starvation-inducible protein PhoH
OB04_02536	COG0561	phosphatase activity
OB04_02539	COG4864	UPF0365 protein
OB04_02540	COG1030	water channel activity
OB04_02541	COG1610	YqeY-like protein
OB04_02542	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OB04_02543	COG1283	sodium-dependent phosphate transmembrane transporter activity
OB04_02544	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OB04_02545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OB04_02546	COG2264	protein methyltransferase activity
OB04_02547	COG0484	heat shock protein binding
OB04_02548	COG0443	Heat shock 70 kDa protein
OB04_02549	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OB04_02550	COG1420	regulation of RNA biosynthetic process
OB04_02551	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OB04_02552	COG0481	GTPase activity
OB04_02554	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_02555	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OB04_02556	COG0268	Binds directly to 16S ribosomal RNA
OB04_02557	COG1466	dna polymerase III delta subunit
OB04_02558	COG0658	competence protein
OB04_02558	COG2333	competence protein COMEC
OB04_02559	COG2131	deaminase
OB04_02560	COG1555	photosystem II stabilization
OB04_02560	COG1596	polysaccharide export
OB04_02561	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OB04_02562	COG2226	methyltransferase
OB04_02563	COG0799	negative regulation of ribosome biogenesis
OB04_02564	COG1713	HD superfamily hydrolase involved in NAD metabolism
OB04_02565	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OB04_02566	COG1534	Rna-binding protein
OB04_02567	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OB04_02568	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OB04_02569	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OB04_02571	COG2755	lipolytic protein G-D-S-L family
OB04_02572	COG3409	Peptidoglycan-binding domain 1 protein
OB04_02572	COG5632	N-Acetylmuramoyl-L-alanine amidase
OB04_02573	COG0398	Pfam SNARE associated Golgi protein
OB04_02574	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OB04_02576	COG3209	COG3209 Rhs family protein
OB04_02578	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OB04_02579	COG2249	NAD(P)H dehydrogenase (quinone) activity
OB04_02581	COG0745	RESPONSE REGULATOR receiver
OB04_02582	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OB04_02584	COG2315	Protein conserved in bacteria
OB04_02585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OB04_02589	COG2272	Belongs to the type-B carboxylesterase lipase family
OB04_02591	COG0457	Tetratricopeptide repeat
OB04_02592	COG5444	nuclease activity
OB04_02599	COG3409	Peptidoglycan-binding domain 1 protein
OB04_02599	COG5632	N-Acetylmuramoyl-L-alanine amidase
OB04_02600	COG1783	phage Terminase large subunit
OB04_02605	COG3677	Transposase
OB04_02609	COG0563	adenylate kinase activity
OB04_02611	COG2856	Zn peptidase
OB04_02615	COG4124	Belongs to the glycosyl hydrolase 26 family
OB04_02616	COG0730	response to heat
OB04_02617	COG0425	Belongs to the sulfur carrier protein TusA family
OB04_02618	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_02618	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OB04_02620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OB04_02620	COG0425	Belongs to the sulfur carrier protein TusA family
OB04_02621	COG2210	Belongs to the sulfur carrier protein TusA family
OB04_02622	COG1937	Protein conserved in bacteria
OB04_02623	COG0662	Cupin 2, conserved barrel domain protein
OB04_02624	COG4978	Transcriptional regulator
OB04_02624	COG0789	Transcriptional regulator
OB04_02625	COG2814	Major facilitator Superfamily
OB04_02626	COG0456	acetyltransferase
OB04_02627	COG1253	flavin adenine dinucleotide binding
OB04_02629	COG0697	spore germination
OB04_02630	COG0583	DNA-binding transcription factor activity
OB04_02631	COG2072	flavoprotein involved in K transport
OB04_02632	COG1230	cation diffusion facilitator family transporter
OB04_02633	COG1942	4-Oxalocrotonate Tautomerase
OB04_02634	COG0583	DNA-binding transcription factor activity
OB04_02635	COG1114	Component of the transport system for branched-chain amino acids
OB04_02636	COG1687	branched-chain amino acid
OB04_02637	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OB04_02638	COG1522	sequence-specific DNA binding
OB04_02639	COG2732	(Barnase) inhibitor
OB04_02640	COG2124	cytochrome p450
OB04_02641	COG1335	isochorismatase
OB04_02643	COG2318	DinB family
OB04_02645	COG2070	2-Nitropropane dioxygenase
OB04_02647	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OB04_02650	COG3443	Belongs to the bacterial solute-binding protein 9 family
OB04_02651	COG1595	DNA-templated transcription, initiation
OB04_02652	COG0667	Aldo Keto reductase
OB04_02653	COG2851	Citrate transporter
OB04_02654	COG0583	DNA-binding transcription factor activity
OB04_02655	COG2828	Protein conserved in bacteria
OB04_02656	COG3409	Peptidoglycan-binding domain 1 protein
OB04_02657	COG5566	PFAM Mor transcription activator
OB04_02658	COG0596	Alpha beta hydrolase
OB04_02659	COG4991	sh3 domain protein
OB04_02660	COG4991	sh3 domain protein
OB04_02661	COG0346	lactoylglutathione lyase activity
OB04_02663	COG5577	PFAM Coat F domain
OB04_02664	COG1063	alcohol dehydrogenase
OB04_02666	COG5577	PFAM Coat F domain
OB04_02667	COG0789	Transcriptional regulator
OB04_02669	COG1064	alcohol dehydrogenase
OB04_02670	COG0693	protein deglycase activity
OB04_02671	COG1621	beta-fructofuranosidase activity
OB04_02672	COG3716	PTS system mannose fructose sorbose family IID component
OB04_02673	COG3715	PTS system
OB04_02674	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_02675	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_02676	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OB04_02676	COG3933	PFAM sigma-54 factor interaction domain-containing protein
OB04_02677	COG1113	amino acid transport
OB04_02678	COG1280	lysine exporter protein (LysE YggA)
OB04_02679	COG1378	Sugar-specific transcriptional regulator TrmB
OB04_02680	COG1595	DNA-templated transcription, initiation
OB04_02682	COG2755	lipolytic protein G-D-S-L family
OB04_02682	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OB04_02684	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OB04_02684	COG2124	cytochrome p450
OB04_02685	COG1309	transcriptional regulator
OB04_02686	COG2226	methyltransferase
OB04_02689	COG2116	formate transmembrane transporter activity
OB04_02691	COG5609	conserved protein (DUF2294)
OB04_02692	COG3383	formate dehydrogenase (NAD+) activity
OB04_02693	COG2427	Protein of unknown function (DUF1641)
OB04_02695	COG0626	cystathionine gamma-synthase activity
OB04_02696	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OB04_02697	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OB04_02698	COG2226	methyltransferase
OB04_02701	COG0768	penicillin binding
OB04_02702	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OB04_02703	COG0572	uridine kinase
OB04_02707	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OB04_02708	COG3906	Belongs to the UPF0473 family
OB04_02709	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OB04_02710	COG4472	Bacterial protein of unknown function (DUF965)
OB04_02711	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OB04_02712	COG0628	permease
OB04_02713	COG1126	abc transporter atp-binding protein
OB04_02714	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_02715	COG0765	amino acid transport
OB04_02716	COG0765	amino acid transport
OB04_02719	COG3881	PFAM PRC-barrel domain
OB04_02720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OB04_02721	COG0457	Tetratricopeptide repeat
OB04_02722	COG0482	sulfurtransferase activity
OB04_02723	COG1104	cysteine desulfurase activity
OB04_02724	COG1959	2 iron, 2 sulfur cluster binding
OB04_02725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OB04_02726	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OB04_02727	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OB04_02728	COG0124	histidyl-tRNA synthetase
OB04_02730	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_02730	COG4991	sh3 domain protein
OB04_02730	COG3103	Sh3 type 3 domain protein
OB04_02731	COG1490	D-aminoacyl-tRNA deacylase activity
OB04_02732	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OB04_02733	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OB04_02734	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OB04_02734	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OB04_02735	COG5416	Lipopolysaccharide assembly protein A domain
OB04_02736	COG0490	domain, Protein
OB04_02737	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OB04_02737	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OB04_02739	COG2244	polysaccharide biosynthetic process
OB04_02740	COG2323	membrane
OB04_02742	COG1862	Preprotein translocase
OB04_02743	COG0343	queuine tRNA-ribosyltransferase activity
OB04_02744	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OB04_02746	COG2255	four-way junction helicase activity
OB04_02747	COG0632	four-way junction helicase activity
OB04_02749	COG2814	Major facilitator Superfamily
OB04_02750	COG0673	inositol 2-dehydrogenase activity
OB04_02751	COG2112	serine threonine protein kinase
OB04_02754	COG1115	amino acid carrier protein
OB04_02755	COG0217	transcriptional regulatory protein
OB04_02757	COG1388	LysM domain
OB04_02758	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OB04_02759	COG0157	Belongs to the NadC ModD family
OB04_02760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OB04_02761	COG1104	cysteine desulfurase activity
OB04_02762	COG1827	regulation of RNA biosynthetic process
OB04_02763	COG0077	Prephenate dehydratase
OB04_02764	COG4492	Belongs to the UPF0735 family
OB04_02765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OB04_02766	COG3290	protein histidine kinase activity
OB04_02767	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OB04_02768	COG2868	ribosomal protein
OB04_02769	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OB04_02770	COG1994	Peptidase M50
OB04_02771	COG0739	heme binding
OB04_02772	COG2894	cell division
OB04_02773	COG0850	regulation of cytokinetic process
OB04_02774	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OB04_02775	COG1792	Involved in formation and maintenance of cell shape
OB04_02776	COG1077	Cell shape determining protein MreB Mrl
OB04_02777	COG2003	Belongs to the UPF0758 family
OB04_02778	COG0424	maF-like protein
OB04_02780	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OB04_02781	COG0285	dihydrofolate synthase activity
OB04_02782	COG0525	valine-tRNA ligase activity
OB04_02784	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OB04_02785	COG1388	LysM domain
OB04_02786	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OB04_02787	COG0113	porphobilinogen synthase activity
OB04_02788	COG1587	Uroporphyrinogen-III synthase
OB04_02789	COG0181	hydroxymethylbilane synthase activity
OB04_02790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OB04_02791	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OB04_02793	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OB04_02794	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OB04_02795	COG0470	DNA polymerase III
OB04_02795	COG1067	ATP-dependent peptidase activity
OB04_02796	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OB04_02797	COG0544	peptidyl-prolyl cis-trans isomerase activity
OB04_02798	COG1477	protein flavinylation
OB04_02798	COG0457	Tetratricopeptide repeat
OB04_02799	COG0066	3-isopropylmalate dehydratase activity
OB04_02800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OB04_02801	COG0473	3-isopropylmalate dehydrogenase activity
OB04_02802	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OB04_02803	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OB04_02804	COG0440	acetolactate synthase activity
OB04_02805	COG0028	Belongs to the TPP enzyme family
OB04_02807	COG0454	-acetyltransferase
OB04_02809	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
OB04_02811	COG0622	Phosphoesterase
OB04_02812	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OB04_02813	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OB04_02814	COG5401	PFAM Sporulation and spore germination
OB04_02815	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OB04_02816	COG1846	Transcriptional regulator
OB04_02817	COG2197	response regulator
OB04_02818	COG0824	Thioesterase
OB04_02819	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OB04_02820	COG1053	succinate dehydrogenase
OB04_02821	COG2009	succinate dehydrogenase
OB04_02822	COG1719	4-vinyl reductase, 4VR
OB04_02823	COG0527	aspartate kinase activity
OB04_02824	COG0322	excinuclease ABC activity
OB04_02825	COG3118	belongs to the thioredoxin family
OB04_02826	COG3534	alpha-L-arabinofuranosidase
OB04_02828	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OB04_02829	COG2086	electron transfer activity
OB04_02830	COG1024	Enoyl-CoA hydratase
OB04_02831	COG1309	transcriptional regulator
OB04_02832	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_02833	COG3766	membrane
OB04_02834	COG1193	negative regulation of DNA recombination
OB04_02835	COG1796	DNA polymerase
OB04_02835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OB04_02836	COG1286	toxin biosynthetic process
OB04_02837	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OB04_02838	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OB04_02839	COG0072	phenylalanine-tRNA ligase activity
OB04_02839	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OB04_02840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OB04_02841	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OB04_02843	COG3835	regulator
OB04_02844	COG0277	FAD linked oxidase domain protein
OB04_02845	COG0247	lactate metabolic process
OB04_02846	COG0346	lactoylglutathione lyase activity
OB04_02848	COG1966	Carbon starvation protein
OB04_02849	COG3534	alpha-L-arabinofuranosidase
OB04_02850	COG0395	ABC-type sugar transport system, permease component
OB04_02851	COG1175	transmembrane transport
OB04_02852	COG1653	transport
OB04_02853	COG0371	Dehydrogenase
OB04_02854	COG0647	UMP catabolic process
OB04_02855	COG0235	Class ii aldolase
OB04_02856	COG1069	ribulokinase activity
OB04_02857	COG2160	L-arabinose isomerase activity
OB04_02858	COG3507	Belongs to the glycosyl hydrolase 43 family
OB04_02859	COG1363	Peptidase, m42
OB04_02861	COG3326	Membrane
OB04_02862	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OB04_02863	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OB04_02864	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OB04_02866	COG1346	cytolysis
OB04_02867	COG1380	Effector of murein hydrolase LrgA
OB04_02868	COG3279	Response regulator of the LytR AlgR family
OB04_02869	COG3275	phosphorelay sensor kinase activity
OB04_02871	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OB04_02873	COG0398	Pfam SNARE associated Golgi protein
OB04_02874	COG1484	DNA-dependent DNA replication
OB04_02875	COG3611	Membrane attachment protein
OB04_02876	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OB04_02877	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OB04_02878	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OB04_02879	COG1733	regulation of RNA biosynthetic process
OB04_02880	COG2814	Major facilitator Superfamily
OB04_02881	COG0656	L-ascorbic acid biosynthetic process
OB04_02882	COG0237	dephospho-CoA kinase activity
OB04_02883	COG1971	Probably functions as a manganese efflux pump
OB04_02884	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OB04_02885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OB04_02885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OB04_02886	COG5002	protein histidine kinase activity
OB04_02887	COG0745	RESPONSE REGULATOR receiver
OB04_02888	COG0039	L-malate dehydrogenase activity
OB04_02889	COG0538	isocitrate dehydrogenase activity
OB04_02890	COG0372	Belongs to the citrate synthase family
OB04_02891	COG2707	UPF0756 membrane protein
OB04_02892	COG0628	permease
OB04_02893	COG3030	protein affecting phage T7 exclusion by the F plasmid
OB04_02894	COG0469	pyruvate kinase activity
OB04_02895	COG0205	6-phosphofructokinase activity
OB04_02896	COG0825	malonyl-CoA metabolic process
OB04_02897	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OB04_02898	COG0281	malic enzyme
OB04_02899	COG0587	DNA-directed DNA polymerase activity
OB04_02903	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OB04_02905	COG4109	DRTGG domain
OB04_02906	COG0730	response to heat
OB04_02907	COG1473	amidohydrolase
OB04_02908	COG0196	riboflavin kinase activity
OB04_02909	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_02910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OB04_02911	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_02912	COG1126	abc transporter atp-binding protein
OB04_02913	COG0765	amino acid transport
OB04_02914	COG0765	amino acid transport
OB04_02915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_02916	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_02917	COG0454	-acetyltransferase
OB04_02918	COG0583	DNA-binding transcription factor activity
OB04_02919	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OB04_02920	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_02922	COG0165	Argininosuccinate lyase
OB04_02923	COG0137	argininosuccinate synthase activity
OB04_02924	COG0521	Mo-molybdopterin cofactor biosynthetic process
OB04_02925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OB04_02926	COG0827	DNA restriction-modification system
OB04_02927	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OB04_02928	COG3874	Sporulation protein YtfJ
OB04_02930	COG1714	RDD family
OB04_02931	COG0616	signal peptide processing
OB04_02932	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OB04_02933	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OB04_02934	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OB04_02936	COG0301	tRNA thio-modification
OB04_02937	COG1104	cysteine desulfurase activity
OB04_02938	COG1114	Component of the transport system for branched-chain amino acids
OB04_02939	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OB04_02940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OB04_02941	COG1309	transcriptional regulator
OB04_02942	COG1956	GAF domain-containing protein
OB04_02943	COG2199	diguanylate cyclase activity
OB04_02943	COG2203	Gaf domain
OB04_02944	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OB04_02946	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OB04_02947	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OB04_02948	COG0454	-acetyltransferase
OB04_02949	COG0517	IMP dehydrogenase activity
OB04_02950	COG0123	including yeast histone deacetylase and acetoin utilization protein
OB04_02951	COG1360	Flagellar Motor Protein
OB04_02952	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OB04_02953	COG1609	Transcriptional regulator
OB04_02954	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OB04_02954	COG1605	Chorismate mutase
OB04_02955	COG3118	belongs to the thioredoxin family
OB04_02956	COG4980	gas vesicle protein
OB04_02957	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OB04_02958	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OB04_02959	COG1674	ftsk spoiiie
OB04_02960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OB04_02961	COG4848	Belongs to the UPF0354 family
OB04_02962	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_02964	COG1363	Peptidase, m42
OB04_02965	COG5584	Small secreted protein
OB04_02966	COG0281	malic enzyme
OB04_02967	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_02968	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OB04_02970	COG0510	thiamine kinase activity
OB04_02971	COG1523	belongs to the glycosyl hydrolase 13 family
OB04_02972	COG1597	lipid kinase activity
OB04_02974	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OB04_02975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OB04_02976	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OB04_02977	COG2252	PERMEase
OB04_02978	COG4473	ABC transporter
OB04_02979	COG1131	(ABC) transporter
OB04_02980	COG1349	DNA-binding transcription factor activity
OB04_02981	COG1187	pseudouridine synthase activity
OB04_02982	COG2244	polysaccharide biosynthetic process
OB04_02983	COG2081	HI0933 family
OB04_02984	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OB04_02986	COG5578	integral membrane protein
OB04_02987	COG0673	inositol 2-dehydrogenase activity
OB04_02988	COG1653	transport
OB04_02989	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OB04_02990	COG4209	transmembrane transport
OB04_02991	COG2207	Transcriptional regulator
OB04_02992	COG1653	transport
OB04_02993	COG0395	ABC-type sugar transport system, permease component
OB04_02994	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OB04_02995	COG2124	cytochrome p450
OB04_02996	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OB04_02998	COG0156	8-amino-7-oxononanoate synthase activity
OB04_02999	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OB04_03001	COG1073	alpha beta
OB04_03006	COG1486	melibiose metabolic process
OB04_03007	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OB04_03008	COG0495	leucyl-tRNA aminoacylation
OB04_03010	COG2202	Pas domain
OB04_03010	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_03011	COG2814	Major facilitator Superfamily
OB04_03012	COG2433	Pfam Transposase IS66
OB04_03013	COG0577	efflux transmembrane transporter activity
OB04_03014	COG1136	(ABC) transporter
OB04_03015	COG2205	protein histidine kinase activity
OB04_03016	COG0745	RESPONSE REGULATOR receiver
OB04_03017	COG0577	efflux transmembrane transporter activity
OB04_03018	COG1136	(ABC) transporter
OB04_03021	COG1131	(ABC) transporter
OB04_03022	COG1725	Transcriptional regulator
OB04_03025	COG1242	4 iron, 4 sulfur cluster binding
OB04_03026	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OB04_03028	COG2267	carboxylic ester hydrolase activity
OB04_03029	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OB04_03030	COG1113	amino acid transport
OB04_03031	COG0367	asparagine synthase
OB04_03032	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OB04_03033	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OB04_03035	COG1506	peptidase
OB04_03036	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OB04_03037	COG1116	anion transmembrane transporter activity
OB04_03038	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OB04_03039	COG0494	nUDIX hydrolase
OB04_03040	COG4824	toxin secretion phage lysis holin
OB04_03041	COG0783	Belongs to the Dps family
OB04_03044	COG1854	S-ribosylhomocysteine lyase activity
OB04_03045	COG0288	reversible hydration of carbon dioxide
OB04_03046	COG0254	rRNA binding
OB04_03047	COG1271	oxidase subunit
OB04_03048	COG1294	oxidase, subunit
OB04_03050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OB04_03051	COG1321	iron dependent repressor
OB04_03051	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OB04_03052	COG1121	(ABC) transporter
OB04_03053	COG0803	Belongs to the bacterial solute-binding protein 9 family
OB04_03054	COG4948	Mandelate Racemase Muconate Lactonizing
OB04_03055	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_03056	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OB04_03057	COG0596	Alpha beta hydrolase
OB04_03058	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OB04_03059	COG1169	isochorismate synthase
OB04_03060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OB04_03061	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OB04_03062	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OB04_03063	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OB04_03064	COG0438	transferase activity, transferring glycosyl groups
OB04_03066	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OB04_03067	COG0438	transferase activity, transferring glycosyl groups
OB04_03068	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OB04_03069	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OB04_03070	COG0058	SHG alpha-glucan phosphorylase activity
OB04_03071	COG0297	glycogen (starch) synthase activity
OB04_03072	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OB04_03073	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OB04_03074	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OB04_03106	COG3859	Proton-coupled thiamine transporter YuaJ
OB04_03107	COG1247	-acetyltransferase
OB04_03108	COG2268	Band 7 protein
OB04_03109	COG1585	Membrane protein implicated in regulation of membrane protease activity
OB04_03110	COG2318	DinB family
OB04_03112	COG1454	alcohol dehydrogenase
OB04_03114	COG1510	regulation of RNA biosynthetic process
OB04_03116	COG0569	domain protein
OB04_03117	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OB04_03118	COG4682	membrane
OB04_03119	COG1705	Flagellar rod assembly protein muramidase FlgJ
OB04_03120	COG0477	Major facilitator Superfamily
OB04_03121	COG5553	Cysteine dioxygenase type I
OB04_03123	COG1968	undecaprenyl-diphosphatase activity
OB04_03124	COG0628	permease
OB04_03125	COG0673	inositol 2-dehydrogenase activity
OB04_03126	COG4806	L-rhamnose isomerase
OB04_03127	COG3254	rhamnose metabolic process
OB04_03128	COG1070	Carbohydrate kinase
OB04_03129	COG1349	DNA-binding transcription factor activity
OB04_03130	COG3347	Dehydrogenase
OB04_03130	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03131	COG0840	transmembrane signaling receptor activity
OB04_03132	COG0840	transmembrane signaling receptor activity
OB04_03133	COG0840	transmembrane signaling receptor activity
OB04_03134	COG0840	transmembrane signaling receptor activity
OB04_03137	COG0432	Pfam Uncharacterised protein family UPF0047
OB04_03138	COG0366	Alpha amylase catalytic
OB04_03139	COG1253	flavin adenine dinucleotide binding
OB04_03140	COG2738	Putative neutral zinc metallopeptidase
OB04_03143	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OB04_03146	COG0166	Belongs to the GPI family
OB04_03147	COG1979	alcohol dehydrogenase
OB04_03148	COG1979	alcohol dehydrogenase
OB04_03149	COG2155	Conserved Protein
OB04_03150	COG1098	S1 RNA binding domain
OB04_03151	COG0436	Aminotransferase
OB04_03152	COG1522	sequence-specific DNA binding
OB04_03153	COG2267	carboxylic ester hydrolase activity
OB04_03155	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OB04_03156	COG2205	protein histidine kinase activity
OB04_03158	COG5018	Exonuclease
OB04_03160	COG2814	Major facilitator Superfamily
OB04_03161	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OB04_03162	COG3011	Protein conserved in bacteria
OB04_03164	COG3290	protein histidine kinase activity
OB04_03165	COG4565	transcriptional regulatory protein
OB04_03170	COG3493	citrate carrier protein
OB04_03172	COG2111	Na H antiporter
OB04_03172	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OB04_03173	COG2111	Na H antiporter
OB04_03174	COG1006	Multisubunit Na H antiporter MnhC subunit
OB04_03175	COG0651	ATP synthesis coupled electron transport
OB04_03176	COG1863	multisubunit Na H antiporter MnhE subunit
OB04_03177	COG2212	antiporter activity
OB04_03178	COG1320	monovalent cation:proton antiporter activity
OB04_03179	COG2050	protein possibly involved in aromatic compounds catabolism
OB04_03180	COG2197	response regulator
OB04_03181	COG4585	Histidine kinase
OB04_03183	COG0142	geranyltranstransferase activity
OB04_03186	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OB04_03187	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OB04_03188	COG1335	isochorismatase
OB04_03189	COG5506	Protein of unknown function (DUF1694)
OB04_03192	COG0628	permease
OB04_03195	COG1418	mRNA catabolic process
OB04_03196	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03198	COG1511	domain protein
OB04_03199	COG0433	COG0433 Predicted ATPase
OB04_03199	COG1674	ftsk spoiiie
OB04_03200	COG4499	WXG100 protein secretion system (Wss), protein YukC
OB04_03201	COG5417	Belongs to the EsaB family
OB04_03202	COG4842	Belongs to the WXG100 family
OB04_03203	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OB04_03203	COG2508	Transcriptional regulator
OB04_03204	COG0686	Belongs to the AlaDH PNT family
OB04_03205	COG5634	Uncharacterized conserved protein (DUF2278)
OB04_03206	COG3251	PFAM MbtH domain protein
OB04_03207	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_03208	COG3433	isochorismatase activity
OB04_03208	COG1535	isochorismatase
OB04_03209	COG1021	2,3-dihydroxybenzoate-AMP ligase
OB04_03210	COG1169	isochorismate synthase
OB04_03211	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03212	COG2819	hydrolase of the alpha beta superfamily
OB04_03213	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OB04_03214	COG1268	BioY protein
OB04_03215	COG2056	Na+-H+ antiporter family
OB04_03216	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OB04_03217	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
OB04_03218	COG3584	3D domain protein
OB04_03220	COG1252	NADH dehydrogenase
OB04_03221	COG0492	ferredoxin-NADP+ reductase activity
OB04_03223	COG0516	GMP reductase activity
OB04_03224	COG2808	Putative FMN-binding domain
OB04_03225	COG0456	acetyltransferase
OB04_03227	COG0316	Belongs to the HesB IscA family
OB04_03228	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OB04_03229	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OB04_03230	COG4844	belongs to the
OB04_03231	COG1252	NADH dehydrogenase
OB04_03232	COG4837	Protein of unknown function (DUF1462)
OB04_03233	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OB04_03234	COG4946	Tricorn protease homolog
OB04_03234	COG1506	peptidase
OB04_03234	COG0823	Involved in the tonB-independent uptake of proteins
OB04_03235	COG0083	homoserine kinase activity
OB04_03236	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OB04_03237	COG0460	homoserine dehydrogenase
OB04_03238	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OB04_03239	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OB04_03240	COG0647	UMP catabolic process
OB04_03241	COG2445	Protein of unknown function DUF86
OB04_03242	COG4470	Protein conserved in bacteria
OB04_03244	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OB04_03245	COG0739	heme binding
OB04_03247	COG3377	Domain of unknown function (DUF1805)
OB04_03248	COG0737	Belongs to the 5'-nucleotidase family
OB04_03249	COG0730	response to heat
OB04_03250	COG1801	Protein of unknown function DUF72
OB04_03252	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OB04_03253	COG2508	Transcriptional regulator
OB04_03254	COG2233	PERMEase
OB04_03255	COG2233	PERMEase
OB04_03256	COG3648	Uricase
OB04_03256	COG3195	allantoin biosynthetic process
OB04_03257	COG2351	hydroxyisourate hydrolase activity
OB04_03258	COG2080	2 iron, 2 sulfur cluster binding
OB04_03259	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OB04_03260	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OB04_03261	COG2068	MobA-Related Protein
OB04_03262	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OB04_03263	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OB04_03264	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OB04_03265	COG2356	endonuclease I
OB04_03266	COG3842	ATPase activity
OB04_03267	COG2188	Transcriptional regulator
OB04_03268	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OB04_03269	COG0395	ABC-type sugar transport system, permease component
OB04_03270	COG1175	transmembrane transport
OB04_03271	COG1653	transport
OB04_03272	COG2222	sugar isomerase
OB04_03273	COG0322	excinuclease ABC activity
OB04_03274	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OB04_03277	COG0719	Fe-S assembly protein
OB04_03278	COG0822	iron-sulfur transferase activity
OB04_03279	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OB04_03280	COG0719	Fe-S assembly protein
OB04_03281	COG0396	ATPase activity
OB04_03282	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OB04_03283	COG1464	Belongs to the NlpA lipoprotein family
OB04_03284	COG2011	ABC-type metal ion transport system permease component
OB04_03285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OB04_03287	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_03288	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OB04_03290	COG0509	glycine decarboxylation via glycine cleavage system
OB04_03291	COG1393	Belongs to the ArsC family
OB04_03292	COG1960	acyl-CoA dehydrogenase activity
OB04_03293	COG0183	Belongs to the thiolase family
OB04_03294	COG1250	3-hydroxyacyl-CoA dehydrogenase
OB04_03294	COG1024	Enoyl-CoA hydratase
OB04_03298	COG5577	PFAM Coat F domain
OB04_03299	COG1846	Transcriptional regulator
OB04_03300	COG0477	Major facilitator Superfamily
OB04_03301	COG1942	4-Oxalocrotonate Tautomerase
OB04_03302	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03303	COG0583	DNA-binding transcription factor activity
OB04_03305	COG1120	ATPase activity
OB04_03308	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03309	COG0783	Belongs to the Dps family
OB04_03310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OB04_03311	COG0745	RESPONSE REGULATOR receiver
OB04_03312	COG2770	Histidine kinase
OB04_03312	COG2205	protein histidine kinase activity
OB04_03313	COG1309	transcriptional regulator
OB04_03314	COG0114	fumarate hydratase activity
OB04_03316	COG0697	spore germination
OB04_03317	COG0814	amino acid
OB04_03319	COG2197	response regulator
OB04_03320	COG4585	Histidine kinase
OB04_03321	COG4758	membrane
OB04_03322	COG3595	metallopeptidase activity
OB04_03323	COG1842	Phage shock protein A
OB04_03324	COG4758	membrane
OB04_03325	COG2814	Major facilitator Superfamily
OB04_03326	COG2096	Adenosyltransferase
OB04_03327	COG1120	ATPase activity
OB04_03328	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_03329	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_03330	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03331	COG3386	PFAM SMP-30 Gluconolaconase
OB04_03332	COG2205	protein histidine kinase activity
OB04_03333	COG0745	RESPONSE REGULATOR receiver
OB04_03335	COG1191	sigma factor activity
OB04_03337	COG2140	Oxalate decarboxylase
OB04_03339	COG0577	efflux transmembrane transporter activity
OB04_03340	COG1136	(ABC) transporter
OB04_03341	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OB04_03342	COG1120	ATPase activity
OB04_03343	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_03344	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_03345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_03346	COG0531	amino acid
OB04_03348	COG1988	membrane-bound metal-dependent
OB04_03349	COG1368	sulfuric ester hydrolase activity
OB04_03350	COG1910	domain protein
OB04_03351	COG0725	ABC transporter, periplasmic molybdate-binding protein
OB04_03352	COG4149	molybdate abc transporter
OB04_03353	COG0656	L-ascorbic acid biosynthetic process
OB04_03355	COG0025	NhaP-type Na H and K H
OB04_03356	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OB04_03357	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OB04_03358	COG3973	AAA domain
OB04_03360	COG2860	membrane
OB04_03361	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OB04_03362	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OB04_03363	COG2217	Heavy metal translocating P-type atpase
OB04_03364	COG2217	Heavy metal translocating P-type atpase
OB04_03365	COG2608	mercury ion transmembrane transporter activity
OB04_03366	COG1937	Protein conserved in bacteria
OB04_03367	COG0673	inositol 2-dehydrogenase activity
OB04_03368	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OB04_03369	COG1289	transmembrane transporter activity
OB04_03371	COG2076	Multidrug Resistance protein
OB04_03372	COG1309	transcriptional regulator
OB04_03373	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OB04_03376	COG0557	exoribonuclease II activity
OB04_03377	COG1647	Serine aminopeptidase, S33
OB04_03378	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OB04_03379	COG0596	Alpha beta hydrolase
OB04_03380	COG1476	TRANSCRIPTIONal
OB04_03381	COG1396	sequence-specific DNA binding
OB04_03382	COG1396	sequence-specific DNA binding
OB04_03383	COG1733	regulation of RNA biosynthetic process
OB04_03384	COG0840	transmembrane signaling receptor activity
OB04_03385	COG1174	glycine betaine transport
OB04_03386	COG1732	Glycine betaine
OB04_03387	COG1174	glycine betaine transport
OB04_03388	COG0517	IMP dehydrogenase activity
OB04_03388	COG1125	glycine betaine transport
OB04_03389	COG1510	regulation of RNA biosynthetic process
OB04_03393	COG5658	integral membrane protein
OB04_03394	COG0640	Transcriptional regulator
OB04_03395	COG1174	glycine betaine transport
OB04_03396	COG1732	Glycine betaine
OB04_03397	COG1174	glycine betaine transport
OB04_03398	COG0517	IMP dehydrogenase activity
OB04_03398	COG1125	glycine betaine transport
OB04_03399	COG1510	regulation of RNA biosynthetic process
OB04_03400	COG2095	MarC family integral membrane protein
OB04_03402	COG3064	Membrane
OB04_03403	COG4640	response to antibiotic
OB04_03404	COG0456	acetyltransferase
OB04_03405	COG0148	phosphopyruvate hydratase activity
OB04_03406	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OB04_03407	COG0149	triose-phosphate isomerase activity
OB04_03408	COG0126	phosphoglycerate kinase activity
OB04_03409	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OB04_03410	COG2390	Transcriptional regulator
OB04_03411	COG2814	Major facilitator Superfamily
OB04_03412	COG1609	Transcriptional regulator
OB04_03413	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_03414	COG0583	DNA-binding transcription factor activity
OB04_03415	COG0697	spore germination
OB04_03416	COG1113	amino acid transport
OB04_03417	COG3858	chitin binding
OB04_03418	COG1556	Lactate utilization protein
OB04_03419	COG1139	Iron-sulfur cluster binding protein
OB04_03420	COG0247	lactate metabolic process
OB04_03421	COG2197	response regulator
OB04_03422	COG4585	Histidine kinase
OB04_03423	COG0842	Transport permease protein
OB04_03424	COG1131	(ABC) transporter
OB04_03425	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OB04_03426	COG1874	Beta-galactosidase
OB04_03427	COG3833	ABC-type maltose transport systems, permease component
OB04_03428	COG1175	transmembrane transport
OB04_03429	COG2182	Extracellular solute-binding protein
OB04_03430	COG1609	Transcriptional regulator
OB04_03431	COG2186	Transcriptional regulator
OB04_03432	COG1620	l-lactate permease
OB04_03433	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OB04_03435	COG5039	Polysaccharide pyruvyl transferase
OB04_03436	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OB04_03437	COG0110	maltose O-acetyltransferase activity
OB04_03438	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OB04_03439	COG2244	polysaccharide biosynthetic process
OB04_03440	COG1216	Glycosyl transferase, family 2
OB04_03441	COG5039	Polysaccharide pyruvyl transferase
OB04_03442	COG1216	Glycosyl transferase, family 2
OB04_03444	COG0438	transferase activity, transferring glycosyl groups
OB04_03445	COG1215	transferase activity, transferring glycosyl groups
OB04_03446	COG0438	transferase activity, transferring glycosyl groups
OB04_03447	COG1086	Polysaccharide biosynthesis protein
OB04_03448	COG0489	protein tyrosine kinase activity
OB04_03449	COG3944	biosynthesis protein
OB04_03450	COG1396	sequence-specific DNA binding
OB04_03451	COG2272	Belongs to the type-B carboxylesterase lipase family
OB04_03453	COG3479	Phenolic acid decarboxylase
OB04_03455	COG1794	racemase activity, acting on amino acids and derivatives
OB04_03456	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OB04_03457	COG1621	beta-fructofuranosidase activity
OB04_03458	COG1621	beta-fructofuranosidase activity
OB04_03459	COG0531	amino acid
OB04_03460	COG1309	transcriptional regulator
OB04_03461	COG2076	Multidrug Resistance protein
OB04_03462	COG2076	Multidrug Resistance protein
OB04_03464	COG0277	FAD linked oxidase domain protein
OB04_03465	COG3621	Patatin-like phospholipase
OB04_03467	COG0740	serine-type endopeptidase activity
OB04_03468	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OB04_03469	COG0366	Alpha amylase catalytic
OB04_03470	COG1554	hydrolase, family 65, central catalytic
OB04_03471	COG5521	maltodextrose utilization protein MalA
OB04_03472	COG3833	ABC-type maltose transport systems, permease component
OB04_03473	COG1175	transmembrane transport
OB04_03474	COG2182	Extracellular solute-binding protein
OB04_03476	COG1609	Transcriptional regulator
OB04_03477	COG1611	Belongs to the LOG family
OB04_03478	COG1694	Mazg nucleotide pyrophosphohydrolase
OB04_03479	COG0659	secondary active sulfate transmembrane transporter activity
OB04_03480	COG0288	reversible hydration of carbon dioxide
OB04_03481	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OB04_03482	COG0577	efflux transmembrane transporter activity
OB04_03483	COG1136	(ABC) transporter
OB04_03484	COG5002	protein histidine kinase activity
OB04_03485	COG0745	RESPONSE REGULATOR receiver
OB04_03487	COG2162	N-hydroxyarylamine O-acetyltransferase activity
OB04_03488	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_03489	COG1481	regulation of sporulation
OB04_03490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OB04_03491	COG1660	Displays ATPase and GTPase activities
OB04_03492	COG1051	belongs to the nudix hydrolase family
OB04_03493	COG0492	ferredoxin-NADP+ reductase activity
OB04_03494	COG0791	NLP P60 protein
OB04_03494	COG3883	PFAM NLP P60 protein
OB04_03495	COG0457	Tetratricopeptide repeat
OB04_03496	COG1132	(ABC) transporter
OB04_03500	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OB04_03500	COG0140	phosphoribosyl-ATP diphosphatase activity
OB04_03501	COG0107	imidazoleglycerol-phosphate synthase activity
OB04_03502	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OB04_03503	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OB04_03504	COG0131	Imidazoleglycerol-phosphate dehydratase
OB04_03505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OB04_03506	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OB04_03507	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OB04_03508	COG4990	cell redox homeostasis
OB04_03509	COG5297	Belongs to the glycosyl hydrolase family 6
OB04_03510	COG0110	maltose O-acetyltransferase activity
OB04_03511	COG0546	phosphoglycolate phosphatase activity
OB04_03512	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OB04_03513	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OB04_03514	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OB04_03515	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OB04_03516	COG0363	glucosamine-6-phosphate deaminase activity
OB04_03518	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OB04_03519	COG1950	PFAM Membrane protein of
OB04_03520	COG1983	PspC domain protein
OB04_03521	COG3595	metallopeptidase activity
OB04_03524	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OB04_03525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OB04_03526	COG0556	nucleotide-excision repair
OB04_03527	COG4897	Protein conserved in bacteria
OB04_03528	COG3848	Pyruvate phosphate dikinase
OB04_03528	COG0574	Belongs to the PEP-utilizing enzyme family
OB04_03529	COG1309	transcriptional regulator
OB04_03530	COG2814	Major facilitator Superfamily
OB04_03531	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OB04_03533	COG3409	Peptidoglycan-binding domain 1 protein
OB04_03533	COG0793	Belongs to the peptidase S41A family
OB04_03534	COG2177	Part of the ABC transporter FtsEX involved in
OB04_03535	COG2884	Cell division ATP-binding protein ftsE
OB04_03536	COG2010	Cytochrome c
OB04_03537	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_03538	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OB04_03539	COG0653	protein targeting
OB04_03540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OB04_03543	COG1516	flagellar protein fliS
OB04_03544	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OB04_03545	COG1334	flagellar protein FlaG
OB04_03546	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OB04_03547	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OB04_03548	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OB04_03550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OB04_03551	COG4786	Flagellar basal body rod
OB04_03551	COG1256	bacterial-type flagellum assembly
OB04_03552	COG3418	PFAM FlgN family protein
OB04_03553	COG2747	anti-sigma28 factor FlgM
OB04_03555	COG1040	competence protein
OB04_03557	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OB04_03558	COG1307	EDD domain protein, DegV family
OB04_03559	COG2197	response regulator
OB04_03560	COG4585	Histidine kinase
OB04_03561	COG1739	Uncharacterized protein family UPF0029
OB04_03562	COG1316	TRANSCRIPTIONal
OB04_03563	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OB04_03564	COG0438	transferase activity, transferring glycosyl groups
OB04_03565	COG1215	transferase activity, transferring glycosyl groups
OB04_03566	COG3206	protein involved in exopolysaccharide biosynthesis
OB04_03567	COG3307	-O-antigen
OB04_03568	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OB04_03569	COG0297	glycogen (starch) synthase activity
OB04_03569	COG0438	transferase activity, transferring glycosyl groups
OB04_03570	COG2244	polysaccharide biosynthetic process
OB04_03572	COG2247	cell wall binding repeat
OB04_03572	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_03573	COG2385	sporulation resulting in formation of a cellular spore
OB04_03573	COG2247	cell wall binding repeat
OB04_03575	COG1316	TRANSCRIPTIONal
OB04_03576	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OB04_03577	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OB04_03578	COG1134	teichoic acid transport
OB04_03579	COG1682	transport, permease protein
OB04_03580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OB04_03581	COG0438	transferase activity, transferring glycosyl groups
OB04_03582	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OB04_03583	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
OB04_03584	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OB04_03586	COG4193	domain, Protein
OB04_03587	COG1482	cell wall glycoprotein biosynthetic process
OB04_03588	COG0697	spore germination
OB04_03589	COG0814	amino acid
OB04_03591	COG2814	Major facilitator Superfamily
OB04_03592	COG1316	TRANSCRIPTIONal
OB04_03593	COG0561	phosphatase activity
OB04_03594	COG0791	NLP P60 protein
OB04_03596	COG2843	Capsule synthesis protein
OB04_03598	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OB04_03599	COG1609	Transcriptional regulator
OB04_03600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OB04_03601	COG1869	D-ribose catabolic process
OB04_03602	COG1129	ABC transporter
OB04_03603	COG1172	Belongs to the binding-protein-dependent transport system permease family
OB04_03604	COG1879	ABC-type sugar transport system periplasmic component
OB04_03605	COG3103	Sh3 type 3 domain protein
OB04_03607	COG2249	NAD(P)H dehydrogenase (quinone) activity
OB04_03608	COG3527	Alpha-acetolactate decarboxylase
OB04_03609	COG0028	Belongs to the TPP enzyme family
OB04_03610	COG0583	DNA-binding transcription factor activity
OB04_03611	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OB04_03614	COG5337	Spore coat protein CotH
OB04_03616	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OB04_03618	COG0405	Gamma-glutamyltransferase
OB04_03619	COG1522	sequence-specific DNA binding
OB04_03620	COG2059	Chromate
OB04_03621	COG2059	Chromate
OB04_03623	COG0655	NAD(P)H dehydrogenase (quinone) activity
OB04_03624	COG0583	DNA-binding transcription factor activity
OB04_03627	COG5444	nuclease activity
OB04_03630	COG5444	nuclease activity
OB04_03633	COG3878	Protein conserved in bacteria
OB04_03634	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OB04_03635	COG4464	protein tyrosine phosphatase activity
OB04_03636	COG0489	protein tyrosine kinase activity
OB04_03637	COG3944	biosynthesis protein
OB04_03639	COG4715	Zinc finger, swim domain protein
OB04_03640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OB04_03641	COG0561	phosphatase activity
OB04_03642	COG1349	DNA-binding transcription factor activity
OB04_03643	COG0629	single-stranded DNA binding
OB04_03646	COG3764	Sortase (surface protein transpeptidase)
OB04_03647	COG2972	Histidine kinase
OB04_03647	COG0745	RESPONSE REGULATOR receiver
OB04_03648	COG1970	mechanosensitive ion channel activity
OB04_03649	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OB04_03650	COG0457	Tetratricopeptide repeat
OB04_03651	COG4786	Flagellar basal body rod
OB04_03652	COG4786	Flagellar basal body rod
OB04_03653	COG1077	Cell shape determining protein MreB Mrl
OB04_03654	COG1609	Transcriptional regulator
OB04_03655	COG1846	Transcriptional regulator
OB04_03656	COG2814	Major facilitator Superfamily
OB04_03657	COG3420	alginic acid biosynthetic process
OB04_03658	COG1953	Uracil, thiamine, allantoin
OB04_03659	COG0477	Major facilitator Superfamily
OB04_03660	COG1335	isochorismatase
OB04_03662	COG0004	ammonium transporteR
OB04_03663	COG0347	Belongs to the P(II) protein family
OB04_03664	COG0671	phosphoesterase, PA-phosphatase related
OB04_03666	COG0739	heme binding
OB04_03667	COG1247	-acetyltransferase
OB04_03670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OB04_03671	COG0789	Transcriptional regulator
OB04_03673	COG2910	NAD(P)H-binding
OB04_03674	COG1959	2 iron, 2 sulfur cluster binding
OB04_03675	COG0804	urea catabolic process
OB04_03676	COG0832	Belongs to the urease beta subunit family
OB04_03677	COG0831	urea catabolic process
OB04_03679	COG3237	CsbD-like
OB04_03680	COG1994	Peptidase M50
OB04_03682	COG0457	Tetratricopeptide repeat
OB04_03683	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OB04_03684	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OB04_03686	COG2304	oxidoreductase activity
OB04_03687	COG2304	oxidoreductase activity
OB04_03688	COG2385	sporulation resulting in formation of a cellular spore
OB04_03689	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OB04_03691	COG4836	Membrane
OB04_03693	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OB04_03694	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OB04_03695	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OB04_03696	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OB04_03697	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OB04_03698	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OB04_03699	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OB04_03700	COG0356	it plays a direct role in the translocation of protons across the membrane
OB04_03702	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OB04_03703	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OB04_03704	COG4475	Protein of unknown function (DUF436)
OB04_03705	COG0698	ribose 5-phosphate isomerase
OB04_03706	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OB04_03707	COG1971	Probably functions as a manganese efflux pump
OB04_03708	COG0009	L-threonylcarbamoyladenylate synthase
OB04_03709	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OB04_03713	COG2890	protein-(glutamine-N5) methyltransferase activity
OB04_03714	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OB04_03715	COG0346	lactoylglutathione lyase activity
OB04_03716	COG0789	Transcriptional regulator
OB04_03717	COG0679	Auxin Efflux Carrier
OB04_03718	COG0281	malic enzyme
OB04_03719	COG1435	thymidine kinase activity
OB04_03720	COG0254	rRNA binding
OB04_03721	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OB04_03722	COG1494	fructose-1,6-bisphosphatase
OB04_03723	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OB04_03724	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OB04_03725	COG0191	fructose-bisphosphate aldolase activity
OB04_03726	COG2204	response regulator
OB04_03727	COG4821	SIS domain
OB04_03728	COG0504	CTP synthase activity
OB04_03729	COG3343	RNA polymerase activity
OB04_03730	COG1960	acyl-CoA dehydrogenase activity
OB04_03731	COG2181	nitrate reductase activity
OB04_03731	COG0247	lactate metabolic process
OB04_03732	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OB04_03733	COG4294	response to UV
OB04_03735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OB04_03736	COG1132	(ABC) transporter
OB04_03737	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OB04_03738	COG2181	nitrate reductase activity
OB04_03739	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OB04_03740	COG1140	nitrate reductase beta subunit
OB04_03741	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OB04_03742	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OB04_03744	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OB04_03745	COG2223	nitrite transmembrane transporter activity
OB04_03746	COG0018	arginyl-trna synthetase
OB04_03747	COG4506	Protein conserved in bacteria
OB04_03749	COG0535	radical SAM domain protein
OB04_03751	COG1131	(ABC) transporter
OB04_03752	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OB04_03753	COG0612	Peptidase, M16
OB04_03754	COG0612	Peptidase, M16
OB04_03756	COG3391	amine dehydrogenase activity
OB04_03757	COG3391	amine dehydrogenase activity
OB04_03758	COG0457	Tetratricopeptide repeat
OB04_03765	COG1131	(ABC) transporter
OB04_03767	COG0010	Belongs to the arginase family
OB04_03768	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OB04_03769	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OB04_03771	COG1994	Peptidase M50
OB04_03772	COG1942	4-Oxalocrotonate Tautomerase
OB04_03773	COG1846	Transcriptional regulator
OB04_03774	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OB04_03776	COG0477	Major facilitator Superfamily
OB04_03777	COG1959	2 iron, 2 sulfur cluster binding
OB04_03778	COG3465	dGTPase activity
OB04_03779	COG1078	dGTPase activity
OB04_03780	COG4844	belongs to the
OB04_03782	COG0697	spore germination
OB04_03783	COG0095	Lipoate-protein ligase
OB04_03784	COG0583	DNA-binding transcription factor activity
OB04_03785	COG0280	phosphate acetyltransferase
OB04_03787	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03788	COG0436	Aminotransferase
OB04_03789	COG2814	Major facilitator Superfamily
OB04_03790	COG0151	Belongs to the GarS family
OB04_03791	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03792	COG1917	Cupin 2, conserved barrel domain protein
OB04_03793	COG0077	Prephenate dehydratase
OB04_03794	COG2814	Major facilitator Superfamily
OB04_03795	COG0833	amino acid
OB04_03796	COG4187	Peptidase family M20/M25/M40
OB04_03797	COG1012	belongs to the aldehyde dehydrogenase family
OB04_03798	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OB04_03800	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
OB04_03801	COG1091	dTDP-4-dehydrorhamnose reductase activity
OB04_03802	COG1088	dTDP-glucose 4,6-dehydratase activity
OB04_03803	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OB04_03804	COG3980	spore coat polysaccharide biosynthesis protein
OB04_03805	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
OB04_03806	COG2089	acid synthase
OB04_03807	COG0456	acetyltransferase
OB04_03808	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OB04_03809	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OB04_03810	COG0463	Glycosyl transferase, family 2
OB04_03812	COG2363	Small membrane protein
OB04_03813	COG2233	PERMEase
OB04_03815	COG1012	belongs to the aldehyde dehydrogenase family
OB04_03816	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OB04_03817	COG1216	Glycosyl transferase, family 2
OB04_03820	COG1695	Transcriptional regulator
OB04_03821	COG0351	phosphomethylpyrimidine kinase
OB04_03823	COG1621	beta-fructofuranosidase activity
OB04_03824	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_03824	COG1263	PTS System
OB04_03825	COG2116	formate transmembrane transporter activity
OB04_03826	COG3711	transcriptional antiterminator
OB04_03828	COG1404	Belongs to the peptidase S8 family
OB04_03829	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_03830	COG0778	Nitroreductase
OB04_03831	COG0772	Belongs to the SEDS family
OB04_03833	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OB04_03834	COG1845	cytochrome c oxidase, subunit III
OB04_03835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OB04_03836	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OB04_03837	COG2261	transglycosylase associated protein
OB04_03838	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OB04_03839	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OB04_03840	COG2246	polysaccharide biosynthetic process
OB04_03841	COG1309	transcriptional regulator
OB04_03843	COG3162	membrane
OB04_03844	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OB04_03845	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OB04_03846	COG2837	iron assimilation
OB04_03847	COG2822	iron ion transport
OB04_03848	COG0672	)-iron permease
OB04_03849	COG0352	thiamine-phosphate diphosphorylase activity
OB04_03850	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OB04_03851	COG0583	DNA-binding transcription factor activity
OB04_03852	COG1380	Effector of murein hydrolase LrgA
OB04_03853	COG1346	cytolysis
OB04_03854	COG2814	Major facilitator Superfamily
OB04_03855	COG4895	conserved protein (DUF2196)
OB04_03856	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OB04_03857	COG0346	lactoylglutathione lyase activity
OB04_03859	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OB04_03860	COG1404	Belongs to the peptidase S8 family
OB04_03861	COG1263	PTS System
OB04_03861	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_03862	COG3711	transcriptional antiterminator
OB04_03863	COG1442	glycosyl transferase family 8
OB04_03864	COG5522	Integral membrane protein (intg_mem_TP0381)
OB04_03865	COG1846	Transcriptional regulator
OB04_03866	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OB04_03867	COG2234	aminopeptidase activity
OB04_03870	COG2814	Major facilitator Superfamily
OB04_03871	COG2357	RelA SpoT domain protein
OB04_03872	COG1575	Belongs to the MenA family. Type 1 subfamily
OB04_03874	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_03875	COG1696	Membrane protein involved in D-alanine export
OB04_03876	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_03877	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OB04_03878	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
OB04_03879	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OB04_03880	COG1486	melibiose metabolic process
OB04_03881	COG1447	Phosphotransferase system cellobiose-specific component IIA
OB04_03882	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OB04_03883	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OB04_03884	COG3711	transcriptional antiterminator
OB04_03884	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_03886	COG2094	Belongs to the DNA glycosylase MPG family
OB04_03887	COG0753	catalase activity
OB04_03888	COG2814	Major facilitator Superfamily
OB04_03889	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OB04_03890	COG1131	(ABC) transporter
OB04_03894	COG1595	DNA-templated transcription, initiation
OB04_03895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OB04_03896	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OB04_03897	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OB04_03898	COG4988	ABC transporter
OB04_03899	COG1294	oxidase, subunit
OB04_03900	COG1271	oxidase subunit
OB04_03901	COG3493	citrate carrier protein
OB04_03902	COG0501	Belongs to the peptidase M48B family
OB04_03904	COG0726	polysaccharide deacetylase
OB04_03905	COG3842	ATPase activity
OB04_03906	COG2508	Transcriptional regulator
OB04_03907	COG1012	belongs to the aldehyde dehydrogenase family
OB04_03908	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_03910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OB04_03912	COG4585	Histidine kinase
OB04_03913	COG2197	response regulator
OB04_03914	COG2195	Cleaves the N-terminal amino acid of tripeptides
OB04_03917	COG4894	glucomannan catabolic process
OB04_03918	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OB04_03919	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OB04_03920	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03921	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OB04_03922	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OB04_03923	COG2610	gluconate transmembrane transporter activity
OB04_03924	COG0500	methyltransferase
OB04_03925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OB04_03928	COG0693	protein deglycase activity
OB04_03928	COG0753	catalase activity
OB04_03929	COG2851	Citrate transporter
OB04_03930	COG2273	Hydrolase Family 16
OB04_03931	COG3711	transcriptional antiterminator
OB04_03933	COG2270	Major facilitator Superfamily
OB04_03934	COG0513	Belongs to the DEAD box helicase family
OB04_03935	COG3401	FG-GAP repeat protein
OB04_03935	COG2755	lipolytic protein G-D-S-L family
OB04_03946	COG3209	COG3209 Rhs family protein
OB04_03947	COG0697	spore germination
OB04_03948	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_03950	COG0589	response to stress
OB04_03951	COG2723	6-phospho-beta-galactosidase activity
OB04_03952	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_03952	COG1263	PTS System
OB04_03952	COG2190	(PTS) system
OB04_03955	COG5444	nuclease activity
OB04_03958	COG3507	Belongs to the glycosyl hydrolase 43 family
OB04_03960	COG2986	histidine ammonia-lyase
OB04_03961	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OB04_03962	COG1228	amidohydrolase
OB04_03963	COG0010	Belongs to the arginase family
OB04_03964	COG0833	amino acid
OB04_03965	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OB04_03966	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OB04_03967	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OB04_03968	COG2390	Transcriptional regulator
OB04_03970	COG3192	ethanolamine utilization protein
OB04_03971	COG2079	MmgE PrpD family protein
OB04_03973	COG1126	abc transporter atp-binding protein
OB04_03974	COG0765	amino acid transport
OB04_03975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_03978	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
OB04_03979	COG0561	phosphatase activity
OB04_03985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_03986	COG5294	Protein conserved in bacteria
OB04_03987	COG0577	efflux transmembrane transporter activity
OB04_03988	COG1136	(ABC) transporter
OB04_03989	COG2205	protein histidine kinase activity
OB04_03990	COG0745	RESPONSE REGULATOR receiver
OB04_03991	COG0191	fructose-bisphosphate aldolase activity
OB04_03992	COG1082	Xylose isomerase domain protein TIM barrel
OB04_03993	COG1082	Xylose isomerase domain protein TIM barrel
OB04_03994	COG0673	inositol 2-dehydrogenase activity
OB04_03995	COG2814	Major facilitator Superfamily
OB04_03996	COG1082	Xylose isomerase domain protein TIM barrel
OB04_03997	COG3962	Belongs to the TPP enzyme family
OB04_03998	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OB04_04000	COG1012	belongs to the aldehyde dehydrogenase family
OB04_04001	COG1349	DNA-binding transcription factor activity
OB04_04002	COG0667	Aldo Keto reductase
OB04_04005	COG2814	Major facilitator Superfamily
OB04_04006	COG0326	Molecular chaperone. Has ATPase activity
OB04_04008	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_04009	COG1309	transcriptional regulator
OB04_04010	COG1012	belongs to the aldehyde dehydrogenase family
OB04_04011	COG0456	acetyltransferase
OB04_04012	COG2850	peptidyl-arginine hydroxylation
OB04_04013	COG2226	methyltransferase
OB04_04016	COG0367	asparagine synthase
OB04_04017	COG2814	Major facilitator Superfamily
OB04_04018	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OB04_04020	COG1714	RDD family
OB04_04021	COG2311	Membrane
OB04_04022	COG1917	Cupin 2, conserved barrel domain protein
OB04_04023	COG1309	transcriptional regulator
OB04_04024	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_04025	COG1846	Transcriptional regulator
OB04_04026	COG1380	Effector of murein hydrolase LrgA
OB04_04027	COG1346	cytolysis
OB04_04028	COG5039	Polysaccharide pyruvyl transferase
OB04_04029	COG1929	Belongs to the glycerate kinase type-1 family
OB04_04030	COG1802	Transcriptional regulator
OB04_04031	COG1070	Carbohydrate kinase
OB04_04032	COG2610	gluconate transmembrane transporter activity
OB04_04033	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OB04_04034	COG0450	alkyl hydroperoxide reductase
OB04_04035	COG3634	alkyl hydroperoxide reductase activity
OB04_04036	COG2723	6-phospho-beta-galactosidase activity
OB04_04037	COG2190	(PTS) system
OB04_04038	COG2188	Transcriptional regulator
OB04_04041	COG1131	(ABC) transporter
OB04_04042	COG1994	Peptidase M50
OB04_04043	COG0535	radical SAM domain protein
OB04_04045	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
OB04_04048	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OB04_04051	COG1063	alcohol dehydrogenase
OB04_04055	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OB04_04056	COG0456	acetyltransferase
OB04_04057	COG0457	Tetratricopeptide repeat
OB04_04059	COG0010	Belongs to the arginase family
OB04_04060	COG0833	amino acid
OB04_04061	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OB04_04062	COG3829	transcription factor binding
OB04_04063	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OB04_04064	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OB04_04065	COG4853	Protein conserved in bacteria
OB04_04066	COG4863	YycH protein
OB04_04067	COG5002	protein histidine kinase activity
OB04_04068	COG0745	RESPONSE REGULATOR receiver
OB04_04074	COG0346	lactoylglutathione lyase activity
OB04_04075	COG0305	Participates in initiation and elongation during chromosome replication
OB04_04078	COG3093	addiction module antidote protein HigA
OB04_04079	COG2807	transmembrane transport
OB04_04080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OB04_04081	COG0359	binds to the 23S rRNA
OB04_04082	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OB04_04083	COG4241	membrane
OB04_04085	COG5577	PFAM Coat F domain
OB04_04086	COG1733	regulation of RNA biosynthetic process
OB04_04087	COG1227	inorganic diphosphatase activity
OB04_04090	COG2271	Major facilitator Superfamily
OB04_04091	COG0789	Transcriptional regulator
OB04_04091	COG4978	Transcriptional regulator
OB04_04093	COG4319	ketosteroid isomerase
OB04_04094	COG1357	PFAM Pentapeptide repeats (8 copies)
OB04_04095	COG2814	Major facilitator Superfamily
OB04_04096	COG0583	DNA-binding transcription factor activity
OB04_04097	COG2153	protein acetylation
OB04_04099	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_04100	COG1846	Transcriptional regulator
OB04_04101	COG2153	protein acetylation
OB04_04102	COG2364	Membrane
OB04_04103	COG0456	acetyltransferase
OB04_04104	COG2315	Protein conserved in bacteria
OB04_04105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OB04_04106	COG2814	Major facilitator Superfamily
OB04_04107	COG1331	Highly conserved protein containing a thioredoxin domain
OB04_04108	COG1266	CAAX protease self-immunity
OB04_04109	COG2814	Major facilitator Superfamily
OB04_04109	COG0477	Major facilitator Superfamily
OB04_04110	COG0110	maltose O-acetyltransferase activity
OB04_04111	COG0346	lactoylglutathione lyase activity
OB04_04112	COG1609	Transcriptional regulator
OB04_04113	COG0708	Exodeoxyribonuclease III
OB04_04114	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OB04_04115	COG0629	single-stranded DNA binding
OB04_04116	COG0360	Binds together with S18 to 16S ribosomal RNA
OB04_04117	COG0012	GTP binding
OB04_04118	COG0243	molybdopterin cofactor binding
OB04_04119	COG4481	Protein conserved in bacteria
OB04_04120	COG3949	Membrane
OB04_04122	COG1475	DNA binding
OB04_04123	COG1192	Involved in chromosome partitioning
OB04_04125	COG1475	DNA binding
OB04_04126	COG0357	Ribosomal RNA small subunit methyltransferase G
OB04_04127	COG0445	tRNA wobble uridine modification
OB04_04128	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OB04_04129	COG1847	R3H domain protein
OB04_04130	COG0706	membrane insertase activity
OB04_04131	COG0594	ribonuclease P activity
OB04_04132	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OB04_04133	COG0592	DNA-directed DNA polymerase activity
OB04_04134	COG2501	S4 domain
OB04_04135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OB04_04137	COG0187	DNA topoisomerase II activity
OB04_04138	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OB04_04145	COG0516	GMP reductase activity
OB04_04145	COG0517	IMP dehydrogenase activity