locus-tag	class	description
HWV68_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HWV68_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HWV68_00015	ENOG410848D	S4 domain protein YaaA
HWV68_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HWV68_00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HWV68_00070	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HWV68_00080	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
HWV68_00085	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
HWV68_00090	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HWV68_00100	ENOG4105ZMH	deoxynucleoside kinase
HWV68_00110	ENOG4105VRS	hydrolase family 18
HWV68_00115	ENOG4105GTG	Isochorismatase
HWV68_00120	ENOG4108Z6B	deaminase
HWV68_00130	ENOG4105C6E	dna polymerase iii
HWV68_00135	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HWV68_00140	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HWV68_00150	ENOG41067KS	pro-sigma K processing
HWV68_00190	ENOG4105CDW	Resistance protein
HWV68_00195	ENOG4105CXN	decarboxylase
HWV68_00200	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HWV68_00205	ENOG4105X0R	protein from nitrogen regulatory protein P-II
HWV68_00210	ENOG4105XVJ	Protein of unknown function (DUF327)
HWV68_00215	ENOG4105FA2	dna polymerase iii
HWV68_00220	ENOG4105MA4	psp1 domain protein
HWV68_00225	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
HWV68_00230	ENOG41060K3	Methyltransferase
HWV68_00235	ENOG4105VC4	domain protein
HWV68_00240	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HWV68_00245	ENOG4105KRN	Transcriptional regulator, abrb family
HWV68_00250	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HWV68_00255	ENOG4105F8V	Hydrolase, tatD family
HWV68_00260	ENOG41069ER	domain protein
HWV68_00270	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HWV68_00275	ENOG4105XFA	sporulation peptidase YabG
HWV68_00280	ENOG4105W42	Veg protein
HWV68_00285	ENOG4105XEW	small acid-soluble spore protein
HWV68_00290	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HWV68_00295	ENOG4105DFT	pur operon repressor
HWV68_00300	ENOG4105KME	endoribonuclease L-psp
HWV68_00305	ENOG4105K4W	Could be involved in septation (By similarity)
HWV68_00310	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HWV68_00315	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HWV68_00320	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HWV68_00325	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HWV68_00335	ENOG4108JA2	transcriptioN-repair coupling factor
HWV68_00340	ENOG4108M14	stage v sporulation protein t
HWV68_00350	ENOG4108IY2	MazG family
HWV68_00355	ENOG41082I2	s4 domain protein
HWV68_00360	ENOG4105VYY	sporulation protein yabp
HWV68_00375	ENOG41060GV	RNA binding s1 domain protein
HWV68_00405	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HWV68_00410	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HWV68_00415	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HWV68_00425	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HWV68_00430	ENOG4107U48	ppic-type peptidyL-prolyl cis-trans isomerase
HWV68_00435	ENOG4105C6T	cysteine synthase
HWV68_00440	ENOG4105CRQ	synthase (Component I)
HWV68_00445	ENOG4105DDQ	anthranilate synthase
HWV68_00450	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
HWV68_00455	ENOG4105EEI	dihydropteroate synthase
HWV68_00460	ENOG4105KRF	dihydroneopterin aldolase
HWV68_00465	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HWV68_00475	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HWV68_00480	ENOG4105CRK	lysyL-tRNA synthetase
HWV68_00565	ENOG4108Z0C	Uvrb UvrC protein
HWV68_00570	ENOG41066A3	ATP guanido phosphotransferase
HWV68_00580	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HWV68_00585	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
HWV68_00590	ENOG4105CTP	PilT protein domain protein
HWV68_00595	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HWV68_00600	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HWV68_00605	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HWV68_00610	ENOG4105D7W	serine acetyltransferase
HWV68_00615	ENOG4105C8N	cysteinyl-tRNA synthetase
HWV68_00620	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HWV68_00625	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HWV68_00630	ENOG4105M0M	Tetracycline resistance protein
HWV68_00650	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HWV68_00665	ENOG4108VZM	50s ribosomal protein L10
HWV68_00675	ENOG4107Y49	methyltransferase
HWV68_00680	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HWV68_00685	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HWV68_00690	ENOG4105XPM	ribosomal protein
HWV68_00695	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HWV68_00700	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HWV68_00705	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HWV68_00710	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HWV68_00715	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
HWV68_00720	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HWV68_00725	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HWV68_00730	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HWV68_00740	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HWV68_00755	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HWV68_00760	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HWV68_00770	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HWV68_00775	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HWV68_00785	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HWV68_00795	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HWV68_00800	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HWV68_00805	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HWV68_00810	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HWV68_00820	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HWV68_00825	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HWV68_00835	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HWV68_00850	ENOG41067V7	50S ribosomal protein L36
HWV68_00855	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HWV68_00860	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HWV68_00865	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HWV68_00870	ENOG4108ZT0	50S ribosomal protein l17
HWV68_00875	ENOG4108JJB	ABC transporter
HWV68_00880	ENOG4108JJB	ABC transporter
HWV68_00885	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HWV68_00890	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HWV68_00895	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HWV68_00900	ENOG4108UJD	30S ribosomal protein S9
HWV68_00905	ENOG4108I0C	methyltransferase
HWV68_00920	ENOG4105D1F	ATP-binding protein
HWV68_00935	ENOG4108NMV	polysaccharide deacetylase
HWV68_01015	ENOG4105CHH	sulfate transporter
HWV68_01025	ENOG4108SA1	esterase
HWV68_01045	ENOG410874W	AraC family transcriptional regulator
HWV68_01050	ENOG4105EHZ	conserved protein UCP016719
HWV68_01055	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HWV68_01075	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HWV68_01085	ENOG4105EWC	Purine nucleoside phosphorylase
HWV68_01115	ENOG4105EMN	RNA polymerase sigma factor
HWV68_01125	ENOG4105C8B	TIGR00159 family
HWV68_01130	ENOG4107U5W	ybbr family
HWV68_01135	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HWV68_01140	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HWV68_01150	ENOG4105D03	DNA-3-methyladenine glycosylase II
HWV68_01160	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HWV68_01165	ENOG4108TWJ	NADH dehydrogenase subunit 5
HWV68_01185	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
HWV68_01190	ENOG4105WAB	arsR family transcriptional regulator
HWV68_01195	ENOG4108RWP	Major Facilitator Superfamily protein
HWV68_01210	ENOG4107ZBH	radical SAM domain protein
HWV68_01215	ENOG41066N6	Abortive infection protein
HWV68_01220	ENOG4108WUZ	(ABC) transporter
HWV68_01260	ENOG4105G0J	serine threonine protein kinase
HWV68_01270	ENOG4106K80	
HWV68_01280	ENOG4106DDH	Sporulation-specific SASP protein
HWV68_01290	ENOG4108HWY	Beta-lactamase
HWV68_01295	ENOG4107E6A	Cytochrome p-450
HWV68_01305	ENOG4107QTZ	amino acid
HWV68_01310	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HWV68_01315	ENOG4105CXY	transporter
HWV68_01325	ENOG410645S	MarR family Transcriptional regulator
HWV68_01330	ENOG4105DCM	major facilitator superfamily
HWV68_01345	ENOG410631K	Membrane
HWV68_01350	ENOG4106AXJ	AraC family transcriptional regulator
HWV68_01355	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HWV68_01360	ENOG4108TCS	Glutamyl endopeptidase
HWV68_01370	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
HWV68_01375	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HWV68_01380	ENOG4107ZTW	SNARE associated Golgi
HWV68_01405	ENOG4105C72	UPF0176 protein
HWV68_01415	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
HWV68_01420	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HWV68_01435	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HWV68_01440	ENOG4108IQI	permease
HWV68_01445	ENOG4108J5H	Homocysteine s-methyltransferase
HWV68_01455	ENOG4105CSV	Glutaminase
HWV68_01470	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
HWV68_01475	ENOG4105C26	Dehydrogenase
HWV68_01480	ENOG4105DJB	Major Facilitator Superfamily
HWV68_01485	ENOG4105EQX	glucarate dehydratase
HWV68_01490	ENOG41073TP	transcriptional regulator
HWV68_01495	ENOG4105CTX	dehydratase
HWV68_01510	ENOG4106UX7	integral membrane protein
HWV68_01515	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HWV68_01550	ENOG4105MUA	Resistance protein
HWV68_01560	ENOG4105DGI	Alkaline phosphatase
HWV68_01565	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HWV68_01570	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HWV68_01575	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HWV68_01580	ENOG4107EPV	Aminotransferase class V
HWV68_01585	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HWV68_01590	ENOG4105J7D	transcriptional regulator
HWV68_01595	ENOG4107RB3	L-asparaginase
HWV68_01600	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
HWV68_01610	ENOG41060AI	SEC-C motif
HWV68_01620	ENOG4107Y7X	LytTR
HWV68_01625	ENOG4108IUW	ABC transporter
HWV68_01630	ENOG4108SDH	ABC, transporter
HWV68_01635	ENOG4107SET	aldo keto reductase
HWV68_01670	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HWV68_01680	ENOG4105DSE	periplasmic solute binding protein
HWV68_01685	ENOG4105DIK	(ABC) transporter
HWV68_01695	ENOG4105DEN	Luciferase family
HWV68_01700	ENOG4108N0M	stress protein
HWV68_01705	ENOG4106FN3	tellurium resistance protein
HWV68_01710	ENOG4106FN3	tellurium resistance protein
HWV68_01715	ENOG4107TS3	membrane protein, TerC
HWV68_01720	ENOG4108TTB	tellurium resistance protein
HWV68_01730	ENOG41079KZ	Major Facilitator Superfamily
HWV68_01735	ENOG4107XZQ	multidrug resistance protein
HWV68_01740	ENOG4108A65	Transcriptional regulator
HWV68_01745	ENOG4108IJ7	Glycine betaine
HWV68_01750	ENOG4107SQ8	Glycine betaine
HWV68_01780	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HWV68_01815	ENOG4105EIG	urea carboxylase-associated protein 1
HWV68_01820	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HWV68_01825	ENOG4105I1F	Resistance protein
HWV68_01830	ENOG4107Z3Y	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HWV68_01835	ENOG41089UC	methyltransferase, type 11
HWV68_01840	ENOG4105C5Q	Transcriptional regulator
HWV68_01845	ENOG4105I82	acetyl xylan esterase
HWV68_01850	ENOG410756H	nucleotidyltransferase
HWV68_01860	ENOG4105C26	Dehydrogenase
HWV68_01865	ENOG4105CK7	Sodium proline symporter
HWV68_01870	ENOG4107YHD	transcriptional regulator
HWV68_01880	ENOG4108PJD	permease
HWV68_01885	ENOG4105U6C	Alpha beta hydrolase fold protein
HWV68_01895	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HWV68_01900	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
HWV68_01905	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HWV68_01910	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HWV68_01930	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
HWV68_01940	ENOG4105CKI	cobalamin synthesis protein
HWV68_01945	ENOG4105E5Q	amino acid AbC transporter
HWV68_01950	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
HWV68_01960	ENOG4105HHM	rdd domain containing protein
HWV68_01970	ENOG4105CS2	ec 3.2.1.21
HWV68_01985	ENOG4105C8Q	Methyl-accepting chemotaxis
HWV68_01990	ENOG41080HJ	6-phospho 3-hexuloisomerase
HWV68_01995	ENOG4108VA3	3-hexulose-6-phosphate synthase
HWV68_02000	ENOG4105KVH	Transcriptional regulator
HWV68_02005	ENOG4105CEY	Amp-dependent synthetase and ligase
HWV68_02035	ENOG4105SX7	Transporter
HWV68_02055	ENOG4105CDA	abc transporter atp-binding protein
HWV68_02060	ENOG4105DRP	amino acid AbC transporter
HWV68_02070	ENOG4106P55	Transcriptional regulator
HWV68_02075	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HWV68_02080	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HWV68_02085	ENOG41069ZX	
HWV68_02090	ENOG41069ZX	
HWV68_02100	ENOG4105DUX	Transporter
HWV68_02115	ENOG4105E1K	spore germination protein
HWV68_02135	ENOG4107WD8	ABC transporter, permease
HWV68_02140	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HWV68_02145	ENOG4105BZU	Histidine kinase
HWV68_02170	ENOG4105CFH	Aspartokinase
HWV68_02175	ENOG4105DHS	permease protein
HWV68_02180	ENOG4105CM4	permease protein
HWV68_02185	ENOG4108IPW	abc transporter atp-binding protein
HWV68_02200	ENOG4105R8C	Transcriptional regulator
HWV68_02205	ENOG4108DBC	nitroreductase
HWV68_02210	ENOG41067V3	Antibiotic biosynthesis monooxygenase
HWV68_02215	ENOG4105YVS	arsR family transcriptional regulator
HWV68_02225	ENOG4108JPW	Aminotransferase
HWV68_02230	ENOG4105C26	Dehydrogenase
HWV68_02240	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HWV68_02245	ENOG4105KTB	nuclear export factor GLE1
HWV68_02250	ENOG4108T5E	Copper resistance protein
HWV68_02255	ENOG4108ZYE	Transcriptional regulator
HWV68_02280	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HWV68_02285	ENOG4108ZX0	Signal peptidase I
HWV68_02310	ENOG4105E7W	lamb ycsf family protein
HWV68_02315	ENOG4105C5A	transporter
HWV68_02320	ENOG4105CFM	UPF0317 protein
HWV68_02325	ENOG4105P4J	Allophanate hydrolase, subunit 1
HWV68_02335	ENOG4107258	Transcriptional regulator
HWV68_02340	ENOG4105XJB	lipolytic protein G-D-S-L family
HWV68_02350	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HWV68_02355	ENOG4107RVG	penicillin-binding protein
HWV68_02360	ENOG4107QM2	Aldo Keto reductase
HWV68_02365	ENOG4105ETD	TRANSCRIPTIONal
HWV68_02375	ENOG4105HMZ	Methyltransferase
HWV68_02380	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HWV68_02395	ENOG410606W	general stress protein
HWV68_02405	ENOG4105VCH	membrane
HWV68_02415	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HWV68_02430	ENOG4105I5R	Uncharacterized protein conserved in bacteria (DUF2334)
HWV68_02435	ENOG4107R8N	Glycosyl transferase, family 2
HWV68_02445	ENOG4105C0X	amino acid
HWV68_02470	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HWV68_02480	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
HWV68_02485	ENOG4105EU9	
HWV68_02490	ENOG4105QVS	general stress protein
HWV68_02495	ENOG41082W1	Cupin 2, conserved barrel domain protein
HWV68_02510	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HWV68_02515	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HWV68_02520	ENOG4108MRH	transcriptional regulatory protein
HWV68_02525	ENOG4107QJT	sodium dicarboxylate symporter
HWV68_02530	ENOG4106F5Q	Membrane
HWV68_02535	ENOG4105CJ1	ABC, transporter
HWV68_02550	ENOG4105FDT	acyl-CoA dehydrogenase
HWV68_02570	ENOG4105SZ6	Thioredoxin
HWV68_02575	ENOG4105CPF	Cell wall formation (By similarity)
HWV68_02580	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HWV68_02585	ENOG4105C1J	atp-dependent rna helicase
HWV68_02590	ENOG410905X	membrane-flanked domain protein
HWV68_02595	ENOG4105CKV	Membrane
HWV68_02605	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HWV68_02610	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
HWV68_02615	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HWV68_02625	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
HWV68_02630	ENOG4107MMM	Anti-sigma-factor antagonist
HWV68_02635	ENOG4105FUA	antagonist
HWV68_02640	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
HWV68_02645	ENOG4107SGM	protein serine threonine phosphatase
HWV68_02650	ENOG4105WN5	stage II sporulation protein
HWV68_02655	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
HWV68_02665	ENOG41064BQ	Phosphatase
HWV68_02680	ENOG4105M5P	UPF0310 protein
HWV68_02685	ENOG4105RV9	Transcriptional regulator
HWV68_02740	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
HWV68_02745	ENOG41068WC	Domain of unknown function (DUF955)
HWV68_02750	ENOG4108IMY	Transcriptional regulator
HWV68_02775	ENOG4108RYM	conjugative transposon protein
HWV68_02780	ENOG4106BHR	ftsk SpoIIIE family protein
HWV68_02785	ENOG4106128	DNA-binding helix-turn-helix protein
HWV68_02825	ENOG4105P1M	Domain of unknown function (DUF1874)
HWV68_02835	ENOG4105K4H	Nlp p60 protein
HWV68_02850	ENOG4108U3J	
HWV68_02865	ENOG41078D9	
HWV68_02870	ENOG4105DEN	Luciferase family
HWV68_02885	ENOG4108W2Y	isochorismatase
HWV68_02890	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
HWV68_02895	ENOG4108HH4	Major Facilitator Superfamily
HWV68_02915	ENOG4108V4B	ThiJ pfpI
HWV68_02920	ENOG4105VEQ	Cold shock protein
HWV68_02925	ENOG4108VJ1	Transcriptional regulator (CarD family
HWV68_02935	ENOG4108MCI	Transcriptional regulator, ARAC family
HWV68_02940	ENOG4108UZ3	Transporter
HWV68_02945	ENOG41086D8	Transcriptional regulator
HWV68_02950	ENOG4107U9B	transcriptional regulator
HWV68_02955	ENOG4105DXI	Major Facilitator superfamily
HWV68_02965	ENOG4105CZ9	Domain of unknown function (DU1801)
HWV68_02970	ENOG4105GIG	
HWV68_02975	ENOG4105T38	integral membrane protein
HWV68_02980	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HWV68_02985	ENOG4108ZMQ	domain protein
HWV68_02990	ENOG4105MJ9	esterase
HWV68_02995	ENOG4107Z6X	Transcriptional regulator
HWV68_03005	ENOG4105KVH	Transcriptional regulator
HWV68_03010	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HWV68_03015	ENOG4105EQ0	Major Facilitator superfamily
HWV68_03020	ENOG4108JGH	Tetr family transcriptional regulator
HWV68_03025	ENOG41082YX	Transcriptional regulator, arsr family
HWV68_03030	ENOG4107R5R	arsenical pump membrane protein
HWV68_03040	ENOG4105Z7P	Acetyltransferase (GNAT) family
HWV68_03045	ENOG4107Y9U	Membrane
HWV68_03055	ENOG4108SQ9	flavin reductase domain protein, FMN-binding
HWV68_03060	ENOG4108ZHR	arsR family transcriptional regulator
HWV68_03065	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HWV68_03080	ENOG4105ENE	Histidine kinase
HWV68_03085	ENOG4108VB1	regulatoR
HWV68_03090	ENOG4105EYF	MMPL domain protein
HWV68_03095	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
HWV68_03100	ENOG4108UQV	Membrane
HWV68_03105	ENOG4108Z5V	transcriptional regulator, merr family
HWV68_03110	ENOG41076HS	cation diffusion facilitator family transporter
HWV68_03115	ENOG4108TVJ	Nitroreductase
HWV68_03120	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
HWV68_03125	ENOG4108VGI	doxx family
HWV68_03130	ENOG4105XXY	Thioredoxin
HWV68_03145	ENOG410900G	Protein of unknown function (DUF421)
HWV68_03150	ENOG4108QY0	Membrane
HWV68_03170	ENOG4105PF9	Transcriptional regulator
HWV68_03180	ENOG4105WQG	acetyltransferase
HWV68_03190	ENOG4105C85	amino acid
HWV68_03200	ENOG41062A4	Transcriptional regulator
HWV68_03205	ENOG4105EYF	MMPL domain protein
HWV68_03210	ENOG4108TVJ	Nitroreductase
HWV68_03215	ENOG4105FS7	Transcriptional regulator
HWV68_03220	ENOG4105C2C	drug resistance transporter, Bcr CflA
HWV68_03230	ENOG4105DRR	Transcriptional regulator, GntR family
HWV68_03235	ENOG4105VRS	hydrolase family 18
HWV68_03250	ENOG4105G6Z	alkaline phosphatase
HWV68_03255	ENOG4108ZMX	Domain of unknown function (DU1801)
HWV68_03265	ENOG4108YM7	Gcn5-related n-acetyltransferase
HWV68_03270	ENOG4107TVP	HD domain protein
HWV68_03275	ENOG41090UD	(LipO)protein
HWV68_03280	ENOG4105F27	Major Facilitator
HWV68_03285	ENOG4105VZJ	PTS System
HWV68_03290	ENOG4105VCP	PTS System
HWV68_03295	ENOG4105CK1	PTS System
HWV68_03300	ENOG4105CS2	ec 3.2.1.21
HWV68_03305	ENOG4108TZY	GntR Family Transcriptional Regulator
HWV68_03310	ENOG4105EVU	fructokinase
HWV68_03315	ENOG4105DG6	mannose-6-phosphate isomerase
HWV68_03320	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
HWV68_03365	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HWV68_03370	ENOG4105K8N	protein family UPF0079, ATPase
HWV68_03375	ENOG41072GX	Peptidase M22 Glycoprotease
HWV68_03380	ENOG410801F	ribosomal-protein-alanine acetyltransferase
HWV68_03385	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HWV68_03390	ENOG4105C5H	ABC transporter
HWV68_03395	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HWV68_03400	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HWV68_03405	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HWV68_03410	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HWV68_03420	ENOG4108TYN	CAAX amino terminal protease family protein
HWV68_03430	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HWV68_03455	ENOG4105DVF	Cytosine-specific methyltransferase
HWV68_03460	ENOG4107RHI	Cytosine-specific methyltransferase
HWV68_03495	ENOG4105PGZ	NB-ARC domain
HWV68_03500	ENOG4105CPQ	Dehydrogenase
HWV68_03505	ENOG4105CT4	transporter
HWV68_03515	ENOG41087YS	Phage shock protein A
HWV68_03520	ENOG4105DQX	Zinc finger domain
HWV68_03525	ENOG4108WV1	Pfam:DUF477
HWV68_03535	ENOG4108ZMR	Ion transport 2 domain-containing protein
HWV68_03540	ENOG4107QNK	)-transporter
HWV68_03570	ENOG4107YUH	hydrolase
HWV68_03580	ENOG4107STQ	Multicopper oxidase
HWV68_03585	ENOG4105C85	amino acid
HWV68_03600	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HWV68_03620	ENOG4105C7N	Xanthine uracil vitamin C permease
HWV68_03645	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HWV68_03650	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HWV68_03655	ENOG4105C83	adenylosuccinate lyase
HWV68_03660	ENOG4105C8V	SAICAR synthetase
HWV68_03665	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
HWV68_03670	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HWV68_03675	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
HWV68_03685	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HWV68_03690	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HWV68_03695	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HWV68_03700	ENOG4105C12	Phosphoribosylglycinamide synthetase
HWV68_03710	ENOG4105DVH	amino acid
HWV68_03725	ENOG4108R5T	secreted protein
HWV68_03730	ENOG4105KGF	protein, YerC YecD
HWV68_03735	ENOG4105CBC	glutamate synthase
HWV68_03740	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
HWV68_03745	ENOG4105C4R	Atp-dependent dna helicase
HWV68_03750	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HWV68_03760	ENOG4105CRN	Aminoglycoside phosphotransferase
HWV68_03765	ENOG4105KT7	mgtC SapB transporter
HWV68_03770	ENOG4105CK7	Sodium proline symporter
HWV68_03775	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HWV68_03780	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HWV68_03785	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HWV68_03790	ENOG4108IG5	Transcriptional regulator
HWV68_03800	ENOG4105CBD	Diacylglycerol kinase
HWV68_03805	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HWV68_03820	ENOG4105D85	methylase
HWV68_03825	ENOG4105F6A	helicase
HWV68_03830	ENOG4105ECI	YeeC-like protein
HWV68_03870	ENOG4105CDY	transcriptional regulatory protein
HWV68_03880	ENOG4105M4P	Tetr family transcriptional regulator
HWV68_03885	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
HWV68_03890	ENOG4107S9F	NmrA family
HWV68_03905	ENOG4105WEF	catalase
HWV68_03910	ENOG4105M18	-acetyltransferase
HWV68_03925	ENOG4105C2F	Histidine kinase
HWV68_03930	ENOG4105EQD	regulatoR
HWV68_03935	ENOG410769Z	extracellular solute-binding protein family 1
HWV68_03940	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HWV68_03945	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HWV68_03950	ENOG4105F5H	Glycosyl Hydrolase Family 88
HWV68_03955	ENOG41075H3	AraC family transcriptional regulator
HWV68_03960	ENOG4107TDE	lipolytic protein G-D-S-L family
HWV68_03975	ENOG4105CX8	fg-gap repeat protein
HWV68_03980	ENOG4105CX8	fg-gap repeat protein
HWV68_03985	ENOG4107TDE	lipolytic protein G-D-S-L family
HWV68_03995	ENOG4105EKC	
HWV68_04000	ENOG4105E0S	extracellular solute-binding protein family 1
HWV68_04010	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HWV68_04015	ENOG4105F8D	glycoside hydrolase family 4
HWV68_04020	ENOG4105H67	Protein of unknown function (DUF421)
HWV68_04025	ENOG4105Z26	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
HWV68_04030	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HWV68_04050	ENOG4106I4J	membrane
HWV68_04055	ENOG4108PCN	EamA-like transporter family
HWV68_04060	ENOG41082F9	transcriptional regulator
HWV68_04065	ENOG41061H0	Monooxygenase
HWV68_04070	ENOG4108R1P	
HWV68_04075	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HWV68_04080	ENOG4105E0M	Sulfatase
HWV68_04085	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
HWV68_04095	ENOG41090R9	glycosyltransferase
HWV68_04100	ENOG4107R51	Glycosyl transferase, family 2
HWV68_04105	ENOG41090R9	glycosyltransferase
HWV68_04110	ENOG4105EU0	Major facilitator Superfamily
HWV68_04120	ENOG4105CUB	amino acid
HWV68_04125	ENOG4105C26	Dehydrogenase
HWV68_04130	ENOG4105FKZ	Methyl-accepting chemotaxis
HWV68_04135	ENOG4105C5H	ABC transporter
HWV68_04145	ENOG4107SWG	transcriptional regulator MERR family
HWV68_04150	ENOG4105DXB	Major Facilitator superfamily
HWV68_04160	ENOG4105C5H	ABC transporter
HWV68_04165	ENOG4105FDU	atp-dependent rna helicase
HWV68_04175	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HWV68_04185	ENOG4105E6M	Sulphatase-modifying factor protein
HWV68_04190	ENOG4105E0A	ABC, transporter
HWV68_04195	ENOG4108U1V	ABC transporter, permease
HWV68_04200	ENOG4105DQ5	transport system permease protein
HWV68_04205	ENOG4108HUF	Transporter
HWV68_04220	ENOG4108J20	pectate lyase
HWV68_04225	ENOG4107QPK	)-transporter
HWV68_04235	ENOG4108MRH	transcriptional regulatory protein
HWV68_04260	ENOG410855V	Acylphosphatase
HWV68_04265	ENOG4108RPX	mosc domain containing protein
HWV68_04285	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
HWV68_04315	ENOG4105GEU	Spore germination protein
HWV68_04325	ENOG4108Q5U	germination protein, ger(x)c family
HWV68_04330	ENOG4105E1K	spore germination protein
HWV68_04335	ENOG4105C5Y	PTS System
HWV68_04340	ENOG4105CG3	alpha amylase, catalytic region
HWV68_04345	ENOG4107414	GntR family transcriptional regulator
HWV68_04350	ENOG4108RCM	Nitroreductase
HWV68_04355	ENOG4105CGH	5'-nucleotidase
HWV68_04360	ENOG4107RKG	DJ-1/PfpI family
HWV68_04375	ENOG4105KJF	protein tyrosine phosphatase
HWV68_04385	ENOG4107U9T	Pfam:Ribonuclease_BN
HWV68_04390	ENOG4108ISG	Major Facilitator
HWV68_04395	ENOG4105UPD	Calcium Proton
HWV68_04405	ENOG4105D8X	mechanosensitive ion channel
HWV68_04425	ENOG4106KE4	Dehydrogenase
HWV68_04430	ENOG4105D7N	magnesium and cobalt transport protein CorA
HWV68_04440	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HWV68_04465	ENOG4107RUY	(E1 component), alpha subunit
HWV68_04475	ENOG4107QKR	Dehydrogenase
HWV68_04485	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HWV68_04490	ENOG41069DP	small acid-soluble spore protein
HWV68_04495	ENOG4105KK4	UPF0060 membrane protein
HWV68_04525	ENOG4105F8D	glycoside hydrolase family 4
HWV68_04530	ENOG4108Q3X	Transcriptional regulator
HWV68_04535	ENOG4105CI1	PTS System
HWV68_04540	ENOG4105BZ1	(ABC) transporter
HWV68_04545	ENOG4105BZ1	(ABC) transporter
HWV68_04555	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HWV68_04560	ENOG4105ID8	Transcriptional regulator, ARAC family
HWV68_04565	ENOG4107QNK	)-transporter
HWV68_04570	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
HWV68_04575	ENOG4105CIB	oxidoreductase Domain protein
HWV68_04580	ENOG4105BZU	Histidine kinase
HWV68_04585	ENOG4105WH1	Two component transcriptional regulator luxr family
HWV68_04590	ENOG4105CJ1	ABC, transporter
HWV68_04595	ENOG41090VJ	ABC-2 type transporter
HWV68_04600	ENOG4108KYE	ABC-2 type transporter
HWV68_04605	ENOG4105U3E	Transcriptional regulator
HWV68_04610	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
HWV68_04615	ENOG4105H93	Acyltransferase family
HWV68_04620	ENOG4105YA8	Transcriptional regulator
HWV68_04625	ENOG4107Y80	Major Facilitator superfamily
HWV68_04630	ENOG4108YYS	metal-dependent hydrolase (By similarity)
HWV68_04635	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HWV68_04640	ENOG410834F	Transcriptional regulator
HWV68_04650	ENOG4108MES	Periplasmic binding protein
HWV68_04655	ENOG4105DQ5	transport system permease protein
HWV68_04660	ENOG4108IHU	transport system permease protein
HWV68_04665	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HWV68_04670	ENOG4107Y03	Nitroreductase
HWV68_04685	ENOG4105ECP	epimerase
HWV68_04700	ENOG4105F27	Major Facilitator
HWV68_04720	ENOG4106AKJ	
HWV68_04725	ENOG4105D74	hydrolase
HWV68_04730	ENOG4105CKK	Glycosyl transferase, family 2
HWV68_04735	ENOG4105EJV	Membrane
HWV68_04740	ENOG41067AE	Membrane-bound metal-dependent hydrolase
HWV68_04745	ENOG4105CEN	a g-specific adenine glycosylase
HWV68_04750	ENOG4106BXE	
HWV68_04755	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
HWV68_04770	ENOG4105EVI	UPF0374 protein
HWV68_04775	ENOG4105BZ1	(ABC) transporter
HWV68_04780	ENOG4107NBY	Membrane
HWV68_04790	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HWV68_04795	ENOG4105G5W	regulator Fur family
HWV68_04905	ENOG4108N23	SpoOM-related protein
HWV68_04920	ENOG4105EC3	peptidase S51, dipeptidase E
HWV68_04925	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HWV68_04930	ENOG4105DNP	FAD linked oxidase domain protein
HWV68_04945	ENOG4105E2Y	ABC, transporter
HWV68_04950	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
HWV68_04955	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HWV68_04960	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HWV68_04970	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HWV68_04975	ENOG4107D63	
HWV68_04980	ENOG4105VZ8	Transcriptional regulator
HWV68_04995	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HWV68_05005	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HWV68_05025	ENOG4105CYN	Serine protein kinase
HWV68_05030	ENOG4106AKX	UPF0229 protein
HWV68_05035	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HWV68_05040	ENOG4105CW7	secretion protein, HlyD family
HWV68_05045	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HWV68_05050	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HWV68_05070	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
HWV68_05075	ENOG4105CZV	ABC transporter
HWV68_05080	ENOG4105CJ1	ABC, transporter
HWV68_05085	ENOG4108TU7	Inherit from COG: (ABC) transporter
HWV68_05090	ENOG4105VEQ	Cold shock protein
HWV68_05100	ENOG4105BZU	Histidine kinase
HWV68_05140	ENOG4108YBP	pseudouridine synthase
HWV68_05150	ENOG41080XP	Cbs domain
HWV68_05155	ENOG4107YBY	Hydrolase
HWV68_05160	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HWV68_05165	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HWV68_05170	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
HWV68_05180	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HWV68_05185	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HWV68_05195	ENOG4105BZU	Histidine kinase
HWV68_05200	ENOG4105WH1	Two component transcriptional regulator luxr family
HWV68_05235	ENOG4105ED1	spovr family
HWV68_05240	ENOG4105G6Z	alkaline phosphatase
HWV68_05255	ENOG4105BZN	citrate synthase
HWV68_05260	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HWV68_05265	ENOG4105CUB	amino acid
HWV68_05270	ENOG4105C8J	)-transporter
HWV68_05275	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HWV68_05290	ENOG4105J37	
HWV68_05295	ENOG4108AEY	RNA polymerase sigma factor
HWV68_05300	ENOG4108FN7	Aldo keto reductase
HWV68_05305	ENOG4105F6E	Acyl-transferase
HWV68_05310	ENOG4105C37	(CBS) domain
HWV68_05320	ENOG4105CHM	Aminotransferase
HWV68_05325	ENOG4105C37	(CBS) domain
HWV68_05335	ENOG4105WMR	Protein CrcB homolog
HWV68_05340	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HWV68_05350	ENOG4105D64	Mechanosensitive ion channel
HWV68_05355	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HWV68_05360	ENOG4107VMI	polysaccharide deacetylase
HWV68_05365	ENOG4105F0I	Aminotransferase
HWV68_05385	ENOG4105BZ1	(ABC) transporter
HWV68_05390	ENOG4105BZ1	(ABC) transporter
HWV68_05415	ENOG410839P	
HWV68_05425	ENOG4106MP8	UPF0754 membrane protein
HWV68_05430	ENOG4105WZB	UPF0342 protein
HWV68_05435	ENOG4105F1N	DNA alkylation repair
HWV68_05445	ENOG4105D4P	Coproporphyrinogen iii oxidase
HWV68_05450	ENOG4107S91	Sodium hydrogen exchanger
HWV68_05455	ENOG4105NCW	Trka-c domain protein
HWV68_05465	ENOG4105CGU	Enoyl-CoA hydratase
HWV68_05475	ENOG4108IUX	(ABC) transporter
HWV68_05480	ENOG4105RHA	ABC transporter, permease
HWV68_05485	ENOG4107VRP	DNA repair exonuclease
HWV68_05490	ENOG4106D4I	domain protein
HWV68_05495	ENOG4105EQI	Metal Dependent Phosphohydrolase
HWV68_05505	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HWV68_05550	ENOG4105NBU	tryptophan transport protein
HWV68_05555	ENOG4105DXJ	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HWV68_05560	ENOG4105K59	histidine triad (HIT) protein
HWV68_05595	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
HWV68_05600	ENOG4105BZ4	penicillin-binding protein
HWV68_05605	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HWV68_05610	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HWV68_05615	ENOG4105C1Q	protoporphyrinogen oxidase
HWV68_05625	ENOG4105ECB	domain protein
HWV68_05635	ENOG41090T1	Membrane
HWV68_05645	ENOG4105DER	m42 family
HWV68_05660	ENOG4106AXD	
HWV68_05665	ENOG4108RQ5	Beta-lactamase domain-containing protein
HWV68_05670	ENOG4105DF9	Lipoate-protein, ligase
HWV68_05680	ENOG4105CEY	Amp-dependent synthetase and ligase
HWV68_05690	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
HWV68_05695	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HWV68_05700	ENOG4105KD7	acetyltransferase
HWV68_05710	ENOG4108HUF	Transporter
HWV68_05715	ENOG4107TB6	phosphoglycerate mutase
HWV68_05725	ENOG4107F3J	Amp-dependent synthetase and ligase
HWV68_05730	ENOG4107ZYJ	bioY protein
HWV68_05735	ENOG4106YBV	Methyl-accepting chemotaxis
HWV68_05755	ENOG4105XVF	Competence transcription factor
HWV68_05760	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HWV68_05765	ENOG4105X3H	Excalibur domain protein
HWV68_05770	ENOG4105E1V	na solute symporter
HWV68_05775	ENOG4106CAD	Protein of unknown function (DUF3311)
HWV68_05780	ENOG41060YP	
HWV68_05795	ENOG4107SCK	Monooxygenase
HWV68_05800	ENOG4108INS	Transcriptional regulator
HWV68_05815	ENOG4105TRI	Hydrolase
HWV68_05830	ENOG4108KK1	membrane protein AbrB duplication
HWV68_05835	ENOG4106K7D	Major facilitator family transporter
HWV68_05840	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
HWV68_05845	ENOG4105VWP	Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding
HWV68_05860	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HWV68_05870	ENOG4105EYH	Exonuclease
HWV68_05920	ENOG4105ERH	Fumarylacetoacetate hydrolase
HWV68_05930	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HWV68_05940	ENOG4105CAQ	asparagine synthetase
HWV68_05955	ENOG4105UQX	Mate efflux family protein
HWV68_05960	ENOG4106HBX	Transcriptional Regulator AraC Family
HWV68_05965	ENOG4105ETE	Transcriptional regulator (LacI family
HWV68_05970	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HWV68_05975	ENOG4105SF0	DinB family
HWV68_05980	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HWV68_05985	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HWV68_05990	ENOG4105MYW	Pentapeptide repeat protein
HWV68_05995	ENOG4107S9D	Alpha beta hydrolase
HWV68_06000	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HWV68_06005	ENOG4107RIQ	Sulfate adenylate transferase
HWV68_06010	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HWV68_06015	ENOG4108N5B	2-phosphosulfolactate phosphatase
HWV68_06020	ENOG41061P3	phosphosulfolactate synthase
HWV68_06030	ENOG4105DIA	mandelate racemase muconate lactonizing
HWV68_06035	ENOG4107RCC	Major Facilitator Superfamily
HWV68_06040	ENOG4108SZE	gCN5-related N-acetyltransferase
HWV68_06045	ENOG4105MA6	gCN5-related N-acetyltransferase
HWV68_06055	ENOG4108VPT	UPF0234 protein
HWV68_06060	ENOG4105QNR	S1 RNA binding domain protein
HWV68_06080	ENOG4105K7K	Transcriptional regulator
HWV68_06090	ENOG410751J	
HWV68_06095	ENOG4105D4Y	metalloprotease
HWV68_06100	ENOG4105EPR	degv family
HWV68_06105	ENOG4107AYK	membrAne
HWV68_06115	ENOG41073B9	
HWV68_06125	ENOG4108KP7	hydrolase
HWV68_06130	ENOG4108MXZ	Esterase
HWV68_06135	ENOG4105VG1	fes assembly suf system protein
HWV68_06145	ENOG4105IQ5	FAD linked oxidase domain protein
HWV68_06155	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HWV68_06160	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HWV68_06170	ENOG4105C8Y	Acetylornithine aminotransferase
HWV68_06175	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HWV68_06185	ENOG4105DBV	ornithine carbamoyltransferase
HWV68_06210	ENOG4107RMD	Basic membrane lipoprotein
HWV68_06225	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HWV68_06230	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HWV68_06240	ENOG4105C3U	ABC transporter
HWV68_06245	ENOG4108JQ7	(ABC) transporter
HWV68_06260	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HWV68_06270	ENOG4105C31	Tryptophanyl-tRNA synthetase
HWV68_06275	ENOG4108J59	Extracellular solute-binding protein, family 5
HWV68_06280	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HWV68_06285	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HWV68_06295	ENOG4108JQ7	(ABC) transporter
HWV68_06310	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HWV68_06315	ENOG4108ZCF	integral membrane protein
HWV68_06325	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HWV68_06340	ENOG4105DPN	Oligoendopeptidase f
HWV68_06350	ENOG4105T58	Dithiol-disulfide isomerase
HWV68_06355	ENOG4108Z18	K06886 hemoglobin
HWV68_06360	ENOG4105E4C	Lytic transglycosylase catalytic
HWV68_06365	ENOG4105MIX	Adenylate cyclase
HWV68_06380	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HWV68_06385	ENOG4105EMS	pseudouridine synthase
HWV68_06400	ENOG4105ETU	transcriptional activator (TenA
HWV68_06405	ENOG4108VEU	Thiamine monophosphate synthase
HWV68_06420	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HWV68_06425	ENOG4105D06	uba thif-type nad fad binding protein
HWV68_06430	ENOG4105DWF	phosphomethylpyrimidine kinase
HWV68_06435	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HWV68_06440	ENOG4107A88	
HWV68_06490	ENOG4105ENA	helicase
HWV68_06505	ENOG4108ZMI	UPF0477 protein
HWV68_06515	ENOG4105C28	cystathionine
HWV68_06520	ENOG4105C28	cystathionine
HWV68_06525	ENOG4105D9U	N-acetyltransferase
HWV68_06530	ENOG4105JHY	Membrane
HWV68_06545	ENOG41068SY	
HWV68_06565	ENOG4107KNS	
HWV68_06590	ENOG4108PSK	reductase
HWV68_06605	ENOG4105DM4	PTS System
HWV68_06610	ENOG4105DG6	mannose-6-phosphate isomerase
HWV68_06615	ENOG4105G7B	Protein of unknown function (DUF2992)
HWV68_06620	ENOG4105VMI	-acetyltransferase
HWV68_06630	ENOG4108Z66	YbaK ebsC protein
HWV68_06645	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HWV68_06655	ENOG4108ZJ4	polysaccharide deacetylase
HWV68_06660	ENOG4107CUJ	Protein of unknown function (DUF2690)
HWV68_06685	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HWV68_06710	ENOG4106A3M	Cytochrome p-450
HWV68_06715	ENOG41087PP	glycosyltransferase MGT family
HWV68_06725	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
HWV68_06730	ENOG4105C4B	ABC transporter, permease
HWV68_06735	ENOG4108IXI	(ABC) transporter
HWV68_06745	ENOG4105Q95	Cupin 2, conserved barrel domain protein
HWV68_06760	ENOG4105D2H	Uronic isomerase
HWV68_06765	ENOG4105CT4	transporter
HWV68_06770	ENOG4105DG4	malate L-lactate dehydrogenase
HWV68_06775	ENOG4105CPQ	Dehydrogenase
HWV68_06780	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HWV68_06785	ENOG4105DMW	Dehydrogenase reductase
HWV68_06790	ENOG4108I5G	Major Facilitator superfamily
HWV68_06795	ENOG4107KJX	Transcriptional regulator
HWV68_06800	ENOG4107QZW	Altronate oxidoreductase
HWV68_06805	ENOG4105CTX	dehydratase
HWV68_06810	ENOG4107TSN	permease
HWV68_06820	ENOG4105JD4	ATPase yjob
HWV68_06835	ENOG41068K0	YCII-related domain
HWV68_06840	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
HWV68_06845	ENOG4105KWG	Pfam:DUF1696
HWV68_06850	ENOG4105K7W	phage-related replication protein
HWV68_06855	ENOG4105WEF	catalase
HWV68_06860	ENOG410635T	phage-like element pbsx protein
HWV68_06905	ENOG4108TFU	terminase (Small subunit)
HWV68_06910	ENOG4105IG6	Phage terminase, large subunit
HWV68_06915	ENOG4108MDF	Phage Portal Protein
HWV68_06940	ENOG41060SN	
HWV68_06955	ENOG4105PQS	phage protein
HWV68_06960	ENOG4105FR7	XkdM protein, phage-like element PBSX
HWV68_06965	ENOG4105MTC	XkdN-like protein
HWV68_06975	ENOG4108FKH	Transglycosylase SLT domain
HWV68_06980	ENOG4108WZM	domain protein
HWV68_06985	ENOG4105X7F	
HWV68_06995	ENOG4105MFU	Protein of unknown function (DUF2634)
HWV68_07000	ENOG41066EA	baseplate J family protein
HWV68_07005	ENOG410906S	phage-like element pbsx protein xkdt
HWV68_07015	ENOG41068G1	
HWV68_07045	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
HWV68_07065	ENOG4105CJ3	phosphate transporter
HWV68_07070	ENOG4107GRR	phosphate transport regulator
HWV68_07075	ENOG4107R7I	amino acid
HWV68_07090	ENOG4105EDW	glycosyl transferase, family 39
HWV68_07095	ENOG4105CKK	Glycosyl transferase, family 2
HWV68_07105	ENOG4105C0H	protease
HWV68_07115	ENOG4108ME1	Peptidase M55 D-aminopeptidase
HWV68_07120	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HWV68_07125	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HWV68_07130	ENOG4105C3U	ABC transporter
HWV68_07140	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HWV68_07145	ENOG4105DTQ	mandelate racemase muconate lactonizing
HWV68_07150	ENOG4107SN7	NLP P60 protein
HWV68_07155	ENOG4108JQ7	(ABC) transporter
HWV68_07160	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HWV68_07165	ENOG4107TUM	Amidinotransferase
HWV68_07170	ENOG4108S4H	thioesterase Superfamily protein
HWV68_07175	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HWV68_07195	ENOG4108428	Inherit from COG: -acetyltransferase
HWV68_07205	ENOG41080TC	multidrug resistance protein
HWV68_07210	ENOG4105CIY	formyltetrahydrofolate deformylase
HWV68_07215	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HWV68_07230	ENOG4105K56	Transcriptional regulator
HWV68_07235	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HWV68_07245	ENOG4107Y2X	deaminase
HWV68_07250	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HWV68_07255	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HWV68_07265	ENOG4108W7F	transporter, permease
HWV68_07270	ENOG4108JJB	ABC transporter
HWV68_07275	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
HWV68_07280	ENOG4108X43	YKOF domain protein
HWV68_07285	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HWV68_07290	ENOG41062D9	Histidine kinase
HWV68_07300	ENOG4106849	propeptide, pepSY amd peptidase M4
HWV68_07310	ENOG4105CJW	magnesium transporter
HWV68_07315	ENOG4105V75	Transcriptional regulator
HWV68_07360	ENOG4105DQE	DNA ligase
HWV68_07365	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HWV68_07370	ENOG4105BZU	Histidine kinase
HWV68_07375	ENOG4107T5V	SNARE associated Golgi
HWV68_07380	ENOG4107TS3	membrane protein, TerC
HWV68_07385	ENOG4108WZW	RNA polymerase sigma
HWV68_07395	ENOG410681C	small acid-soluble spore protein
HWV68_07405	ENOG4105D0M	Protease HtpX homolog
HWV68_07425	ENOG4108TGC	Acyltransferase
HWV68_07430	ENOG4105BZU	Histidine kinase
HWV68_07435	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HWV68_07445	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HWV68_07450	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
HWV68_07455	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HWV68_07465	ENOG4107T6J	Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit
HWV68_07470	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
HWV68_07475	ENOG4107V49	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
HWV68_07480	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
HWV68_07500	ENOG4105BZU	Histidine kinase
HWV68_07505	ENOG41090MY	MarR family Transcriptional regulator
HWV68_07510	ENOG4105ER2	Ompa motb domain protein
HWV68_07515	ENOG4105E14	MotA TolQ exbB proton channel
HWV68_07525	ENOG4108K88	Membrane
HWV68_07530	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HWV68_07535	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
HWV68_07540	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HWV68_07545	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HWV68_07555	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HWV68_07560	ENOG4105FEA	Spore maturation protein
HWV68_07590	ENOG4105F0V	Cell wall hydrolase
HWV68_07605	ENOG4105C59	p-type ATPase
HWV68_07615	ENOG4105DC7	peptidase M24
HWV68_07625	ENOG4105CID	antiterminator
HWV68_07635	ENOG4105KRI	phosphocarrier protein (HPr
HWV68_07640	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HWV68_07650	ENOG4105F6S	Spore photoproduct lyase
HWV68_07660	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
HWV68_07665	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HWV68_07670	ENOG4105K4I	Scp-like extracellular
HWV68_07680	ENOG4105BZU	Histidine kinase
HWV68_07685	ENOG4105CHM	Aminotransferase
HWV68_07695	ENOG4107R88	Chemotaxis protein (CheV)
HWV68_07700	ENOG4105UIN	
HWV68_07710	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
HWV68_07720	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HWV68_07725	ENOG4105ESF	Peptidoglycan binding domain protein
HWV68_07730	ENOG4105ESF	Peptidoglycan binding domain protein
HWV68_07740	ENOG4105EPM	Diguanylate phosphodiesterase
HWV68_07745	ENOG4107IN1	Protein of unknown function (DUF1797)
HWV68_07750	ENOG4108XRC	Protein of unknown function (DUF458) 
HWV68_07780	ENOG4105NQC	Flavodoxin
HWV68_07790	ENOG4105CH2	amidohydrolase
HWV68_07800	ENOG4105D8X	mechanosensitive ion channel
HWV68_07805	ENOG4105D3R	alkyl hydroperoxide reductase
HWV68_07810	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HWV68_07825	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HWV68_07830	ENOG4105D06	uba thif-type nad fad binding protein
HWV68_07835	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HWV68_07840	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
HWV68_07845	ENOG4108ZAF	Molybdopterin
HWV68_07850	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
HWV68_07855	ENOG4105BZ1	(ABC) transporter
HWV68_07860	ENOG4105BZ1	(ABC) transporter
HWV68_07870	ENOG4107X8C	Efflux transporter RND family MFP subunit
HWV68_07875	ENOG4105C19	ABC transporter
HWV68_07880	ENOG4107RBB	ABC transporter, permease
HWV68_07885	ENOG4105E98	transcriptional regulator DeoR family
HWV68_07890	ENOG4105DE4	1-phosphofructokinase
HWV68_07895	ENOG4105DM4	PTS System
HWV68_07900	ENOG4105C3F	Signal peptidase i
HWV68_07910	ENOG4105C5H	ABC transporter
HWV68_07915	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HWV68_07940	ENOG4105BZU	Histidine kinase
HWV68_07950	ENOG4107ZYR	domain protein
HWV68_07960	ENOG4105CN5	Metallo-Beta-Lactamase
HWV68_07970	ENOG4108X4Q	Hydrolase
HWV68_07975	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HWV68_07995	ENOG4105CPP	Dehydrogenase, E1 component
HWV68_08000	ENOG4105C7S	Dehydrogenase
HWV68_08005	ENOG4107QN2	dihydrolipoyl dehydrogenase
HWV68_08020	ENOG4105CXN	decarboxylase
HWV68_08025	ENOG4105WBI	UPF0223 protein
HWV68_08040	ENOG4105ECY	inositol monophosphatase
HWV68_08050	ENOG4105JQZ	Methyltransferase
HWV68_08090	ENOG4105CI3	gtp-binding protein typa
HWV68_08095	ENOG4105QA2	
HWV68_08110	ENOG4108IAB	Phoh family
HWV68_08120	ENOG4105CSV	Glutaminase
HWV68_08125	ENOG4105ZPI	UPF0358 protein
HWV68_08130	ENOG4105CNI	cell division protein FtsW
HWV68_08135	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HWV68_08145	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HWV68_08155	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HWV68_08160	ENOG4105CCU	oxidase (Subunit III)
HWV68_08165	ENOG41064X9	cytochrome C oxidase subunit IV
HWV68_08180	ENOG41080XQ	Signal transduction protein with cbs domains
HWV68_08185	ENOG4106UY4	Inherit from COG: Scp-like extracellular
HWV68_08205	ENOG4105WUC	UPF0298 protein
HWV68_08210	ENOG4106H78	methyltransferase
HWV68_08215	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HWV68_08220	ENOG4105H20	Sporulation integral membrane protein YlbJ
HWV68_08225	ENOG4105D78	K07001 NTE family protein
HWV68_08230	ENOG41063PX	domain protein
HWV68_08235	ENOG4105CDE	UPF0348 protein
HWV68_08245	ENOG4105KNH	Nucleic acid-binding protein
HWV68_08275	ENOG4108V6E	Cell division protein mraZ
HWV68_08280	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HWV68_08290	ENOG4105CJN	penicillin-binding protein
HWV68_08295	ENOG4105CJN	penicillin-binding protein
HWV68_08300	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HWV68_08305	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HWV68_08310	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HWV68_08315	ENOG4105CNI	cell division protein FtsW
HWV68_08320	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HWV68_08325	ENOG4105D4A	Cell wall formation (By similarity)
HWV68_08330	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
HWV68_08335	ENOG4108R2U	division initiation protein
HWV68_08345	ENOG4105K67	small basic protein
HWV68_08350	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HWV68_08355	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HWV68_08365	ENOG4105FFI	sigma-e processing peptidase spoiiga
HWV68_08370	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HWV68_08380	ENOG4105DKW	ABC transporter
HWV68_08390	ENOG4105WR5	sporulation protein, YlmC YmxH family
HWV68_08395	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HWV68_08400	ENOG4105DFA	alanine racemase domain protein
HWV68_08405	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HWV68_08410	ENOG41067XK	integral membrane protein
HWV68_08415	ENOG4105DBK	s4 domain protein
HWV68_08425	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HWV68_08435	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HWV68_08440	ENOG4105C34	Pseudouridine synthase
HWV68_08445	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HWV68_08455	ENOG4105CXT	aspartate transcarbamylase
HWV68_08465	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HWV68_08470	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HWV68_08475	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
HWV68_08480	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
HWV68_08485	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HWV68_08490	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HWV68_08495	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HWV68_08505	ENOG4107S4M	Sulfate adenylate transferase
HWV68_08510	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HWV68_08515	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HWV68_08520	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
HWV68_08525	ENOG41087GM	Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein
HWV68_08540	ENOG4105DSJ	YicC domain protein
HWV68_08545	ENOG4105KC4	UPF0296 protein
HWV68_08550	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HWV68_08560	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HWV68_08565	ENOG4105C25	Primosomal protein n'
HWV68_08570	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HWV68_08575	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HWV68_08580	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HWV68_08585	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HWV68_08590	ENOG4108ZF3	Phosphatase
HWV68_08595	ENOG4105D9P	serine threonine protein kinase
HWV68_08600	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HWV68_08605	ENOG4105DJV	ribulose-phosphate 3-epimerase
HWV68_08610	ENOG4105FJ0	thiamine
HWV68_08620	ENOG4105VB9	50S ribosomal protein l28
HWV68_08625	ENOG4108ZAA	Alkaline-shock protein
HWV68_08630	ENOG4105DP4	dak2 domain fusion protein ylov
HWV68_08640	ENOG4105EJQ	L-serine dehydratase
HWV68_08645	ENOG4105CB5	ATP-dependent DNA helicase recG
HWV68_08650	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
HWV68_08660	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HWV68_08665	ENOG4105CHR	reductase
HWV68_08675	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HWV68_08680	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HWV68_08685	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HWV68_08695	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
HWV68_08705	ENOG4105K5M	30s ribosomal protein S16
HWV68_08710	ENOG4108BW8	UPF0109 protein
HWV68_08720	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HWV68_08725	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HWV68_08730	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HWV68_08735	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HWV68_08740	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HWV68_08750	ENOG4105VM1	flagellar
HWV68_08755	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HWV68_08760	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HWV68_08765	ENOG4105C79	DNA protecting protein DprA
HWV68_08770	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HWV68_08775	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
HWV68_08780	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HWV68_08785	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HWV68_08790	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HWV68_08800	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HWV68_08805	ENOG4108ZC9	flagellar basal-body rod protein flgc
HWV68_08810	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HWV68_08815	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HWV68_08820	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HWV68_08835	ENOG4106YF4	Flagellar biosynthesis chaperone
HWV68_08845	ENOG410696Y	Flagellar hook-length control protein
HWV68_08850	ENOG410822I	Flagellar hook capping protein
HWV68_08855	ENOG4108JQA	flagellar
HWV68_08860	ENOG41068WV	flagellar FlbD family protein
HWV68_08870	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HWV68_08875	ENOG4105DD5	Flagellar motor switch protein
HWV68_08880	ENOG4107YTP	response regulator receiver protein
HWV68_08890	ENOG4105CN7	Flagellar biosynthetic protein FliP
HWV68_08895	ENOG4105VS8	Flagellar biosynthetic protein fliq
HWV68_08900	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HWV68_08905	ENOG4105D00	flagellar biosynthetic protein flhB
HWV68_08910	ENOG4105D7B	Flagellar biosynthesis protein flha
HWV68_08915	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HWV68_08925	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HWV68_08930	ENOG4105CBS	Chea signal transduction histidine kinase
HWV68_08935	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
HWV68_08950	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HWV68_08960	ENOG4105CE9	30S ribosomal protein S2
HWV68_08965	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HWV68_08975	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HWV68_08980	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HWV68_08985	ENOG4105KNE	Phosphatidate cytidylyltransferase
HWV68_08995	ENOG4105DZP	Membrane-associated zinc metalloprotease
HWV68_09000	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HWV68_09005	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HWV68_09010	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HWV68_09015	ENOG4105CHV	Transcription elongation factor NusA
HWV68_09020	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
HWV68_09025	ENOG4105VHM	ribosomal protein
HWV68_09030	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HWV68_09035	ENOG4105W7A	Protein of unknown function (DUF503)
HWV68_09040	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HWV68_09045	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HWV68_09050	ENOG4105DTN	riboflavin biosynthesis protein ribF
HWV68_09055	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HWV68_09060	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HWV68_09070	ENOG4105C1V	Peptidase, M16
HWV68_09080	ENOG4105E35	Dipicolinate synthase subunit A
HWV68_09085	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
HWV68_09090	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HWV68_09100	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HWV68_09110	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
HWV68_09120	ENOG4105CNU	cell division protein FtsK
HWV68_09125	ENOG4105FDP	GntR family transcriptional regulator
HWV68_09145	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
HWV68_09150	ENOG4105XZV	Protein of unknown function (DUF3243)
HWV68_09165	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HWV68_09170	ENOG4105CEV	competence damage-inducible protein
HWV68_09180	ENOG4108A04	Beta-lactamase
HWV68_09185	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HWV68_09190	ENOG4105D48	metallophosphoesterase
HWV68_09195	ENOG4105MCT	stage V sporulation protein S
HWV68_09205	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HWV68_09210	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HWV68_09225	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HWV68_09230	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HWV68_09240	ENOG4105IIP	Membrane
HWV68_09245	ENOG4105W1N	transcriptional regulator
HWV68_09250	ENOG4108151	Beta-lactamase domain protein
HWV68_09260	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HWV68_09270	ENOG4107QKG	PfaD family
HWV68_09275	ENOG41062T2	Acyl carrier protein
HWV68_09280	ENOG4108MH3	Polyketide beta-ketoacyl acyl carrier protein synthase
HWV68_09285	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
HWV68_09290	ENOG4108MGH	Enoyl-CoA hydratase
HWV68_09295	ENOG4108KQ6	Enoyl-CoA hydratase
HWV68_09300	ENOG4105C0W	non-ribosomal peptide synthetase
HWV68_09305	ENOG4107SQU	synthase
HWV68_09315	ENOG4105C0W	non-ribosomal peptide synthetase
HWV68_09325	ENOG4106A3M	Cytochrome p-450
HWV68_09340	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HWV68_09345	ENOG4105K7W	phage-related replication protein
HWV68_09350	ENOG4108X3M	OsmC Ohr family protein
HWV68_09355	ENOG410814C	multidrug resistance protein
HWV68_09375	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HWV68_09380	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HWV68_09395	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HWV68_09400	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HWV68_09405	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HWV68_09410	ENOG4105U6W	MutT NUDIX family protein
HWV68_09415	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HWV68_09420	ENOG4106F1P	AAA ATPase, central domain protein
HWV68_09425	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HWV68_09430	ENOG4105CXI	aluminum resistance protein
HWV68_09435	ENOG4105KV4	Transcriptional regulator
HWV68_09440	ENOG4105C5F	glutamine synthetase
HWV68_09445	ENOG41079P0	
HWV68_09465	ENOG4107AUC	
HWV68_09500	ENOG410907G	
HWV68_09505	ENOG4105CT4	transporter
HWV68_09510	ENOG4105DSG	hydrolase family 43
HWV68_09515	ENOG4105E2R	ROK family
HWV68_09520	ENOG4105C93	Xylose Isomerase
HWV68_09525	ENOG4105CMG	Carbohydrate kinase
HWV68_09535	ENOG4107Y9E	nuclease
HWV68_09540	ENOG4105C54	Major Facilitator superfamily
HWV68_09545	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HWV68_09555	ENOG4107YUK	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HWV68_09570	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HWV68_09625	ENOG4108Q8B	Spore germination protein
HWV68_09630	ENOG4108NHD	germination protein
HWV68_09645	ENOG4105FVX	
HWV68_09655	ENOG4105K7W	phage-related replication protein
HWV68_09665	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
HWV68_09670	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HWV68_09680	ENOG4108SVB	resolvase
HWV68_09685	ENOG4105VPS	UPF0291 protein
HWV68_09690	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HWV68_09710	ENOG4107QIV	Cytochrome c biogenesis protein
HWV68_09735	ENOG4107DZX	Small, acid-soluble spore protein P
HWV68_09745	ENOG4108I0Z	Aconitate hydratase
HWV68_09750	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HWV68_09765	ENOG41067CD	Small, acid-soluble spore protein Tlp
HWV68_09775	ENOG4105MI2	
HWV68_09780	ENOG4105W8X	HesB YadR YfhF-family protein
HWV68_09785	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HWV68_09790	ENOG4105K4P	CoA-binding domain protein
HWV68_09795	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HWV68_09815	ENOG4107QWR	cellulase (EC 3.2.1.4)
HWV68_09825	ENOG4108MYR	Secreted protein
HWV68_09830	ENOG4107SYN	Glycosyl hydrolases family 43
HWV68_09840	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HWV68_09845	ENOG4107T5V	SNARE associated Golgi
HWV68_09855	ENOG4107QX3	carboxylase
HWV68_09860	ENOG4105E39	Enoyl-CoA hydratase
HWV68_09865	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HWV68_09870	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
HWV68_09875	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HWV68_09880	ENOG4105CEY	Amp-dependent synthetase and ligase
HWV68_09885	ENOG4105C1G	acyl-Coa dehydrogenase
HWV68_09900	ENOG4105F32	YngK protein
HWV68_09905	ENOG4106U2H	Protein of unknown function (DUF1360)
HWV68_09915	ENOG4105CEY	Amp-dependent synthetase and ligase
HWV68_09920	ENOG4105C0W	non-ribosomal peptide synthetase
HWV68_09930	ENOG4105C0W	non-ribosomal peptide synthetase
HWV68_09935	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HWV68_09940	ENOG4108N2V	aldose 1-epimerase
HWV68_09945	ENOG4107QJQ	Mate efflux family protein
HWV68_09970	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HWV68_09975	ENOG4105SKE	transcriptional Regulator LysR family
HWV68_09980	ENOG4105CB2	alcohol dehydrogenase
HWV68_09985	ENOG4105BZ8	glutamate synthase
HWV68_09990	ENOG4105CBC	glutamate synthase
HWV68_09995	ENOG4105C5Q	Transcriptional regulator
HWV68_10000	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HWV68_10005	ENOG4105II7	pyrroline-5-carboxylate reductase
HWV68_10025	ENOG4108UB7	
HWV68_10030	ENOG41068WN	
HWV68_10035	ENOG4105IE8	Alpha-ketoglutarate permease
HWV68_10040	ENOG4107U6E	carbohydrate kinase FGGY
HWV68_10045	ENOG4108M3J	Dehydrogenase
HWV68_10050	ENOG4108J2R	molybdopterin oxidoreductase
HWV68_10080	ENOG4105EC8	Methyl-accepting chemotaxis
HWV68_10090	ENOG4108YQE	rare lipoprotein a
HWV68_10095	ENOG4105XPP	Protein of unknown function (DUF1275)
HWV68_10100	ENOG4108NR7	pectate lyase
HWV68_10105	ENOG4108RAV	Conserved protein
HWV68_10115	ENOG4105F0F	Oxalate decarboxylase
HWV68_10130	ENOG4105EPI	acetyltransferase, (GNAT) family
HWV68_10150	ENOG41073R8	VanW family
HWV68_10160	ENOG4105VMP	Transcriptional regulator
HWV68_10165	ENOG4105NX3	Membrane
HWV68_10175	ENOG4108Q5Y	Membrane
HWV68_10185	ENOG4108V4B	ThiJ pfpI
HWV68_10190	ENOG4108J4B	Beta-lactamase
HWV68_10205	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HWV68_10210	ENOG4107T94	Endo-14-beta-xylanase
HWV68_10215	ENOG4105YB8	TM2 domain containing protein
HWV68_10220	ENOG4108IMY	Transcriptional regulator
HWV68_10235	ENOG4108RAV	Conserved protein
HWV68_10240	ENOG41079CX	
HWV68_10270	ENOG410780I	phosphoprotein phosphatase activity
HWV68_10295	ENOG4105DB4	
HWV68_10315	ENOG4106ANW	SMI1_KNR4
HWV68_10320	ENOG4106BHF	
HWV68_10340	ENOG4108Z7R	Chaperone CsaA
HWV68_10345	ENOG4105FTV	AraC Family Transcriptional Regulator
HWV68_10350	ENOG4108HJF	gCN5-related N-acetyltransferase
HWV68_10360	ENOG4108W8B	Beta-lactamase domain protein
HWV68_10370	ENOG4105D29	Helix-turn-helix type 11 domain protein
HWV68_10380	ENOG4105KTU	Transcriptional regulator, arsr family
HWV68_10390	ENOG4108SJC	Membrane
HWV68_10410	ENOG4105ECK	Fatty Acid Desaturase
HWV68_10415	ENOG4108ZGX	Histidine kinase
HWV68_10420	ENOG4108S01	response regulator
HWV68_10425	ENOG41069ER	domain protein
HWV68_10430	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HWV68_10440	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HWV68_10445	ENOG4105SCY	DNAK suppressor
HWV68_10485	ENOG4105C26	Dehydrogenase
HWV68_10490	ENOG4105EWU	Squalene--hopene cyclase
HWV68_10495	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HWV68_10500	ENOG4105C8J	)-transporter
HWV68_10505	ENOG4105C09	Bile acid
HWV68_10510	ENOG4105C7S	Dehydrogenase
HWV68_10520	ENOG4107T89	von Willebrand factor, type A
HWV68_10525	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
HWV68_10535	ENOG4105K4H	Nlp p60 protein
HWV68_10540	ENOG41087PP	glycosyltransferase MGT family
HWV68_10550	ENOG4107QMU	Mate efflux family protein
HWV68_10555	ENOG4106SCS	STAS domain
HWV68_10575	ENOG4105FR1	rard protein
HWV68_10590	ENOG4105C6Z	Gluconate
HWV68_10595	ENOG41090U3	tautomerase
HWV68_10610	ENOG4105FBA	Phospholipase Carboxylesterase
HWV68_10625	ENOG4105E1V	na solute symporter
HWV68_10645	ENOG4108VXD	carboxy-peptidase
HWV68_10650	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HWV68_10660	ENOG4106Z5R	
HWV68_10665	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HWV68_10695	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HWV68_10700	ENOG4108TSC	N-acetyltransferase
HWV68_10705	ENOG4107S4Y	M20 DapE family protein YgeY
HWV68_10720	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HWV68_10760	ENOG4107T32	3-phytase (EC 3.1.3.8)
HWV68_10765	ENOG4105C5E	polysaccharide biosynthesis protein
HWV68_10775	ENOG4106Y37	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
HWV68_10865	ENOG4105FTQ	Dna gyrase
HWV68_10870	ENOG4107YUK	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HWV68_10875	ENOG4106ITI	Glutaredoxin
HWV68_10895	ENOG4107S45	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HWV68_10900	ENOG4107S45	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HWV68_10905	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HWV68_10995	ENOG4105DVF	Cytosine-specific methyltransferase
HWV68_11005	ENOG4106210	phosphatase activity
HWV68_11040	ENOG4106J9J	DNA polymerase
HWV68_11050	ENOG4106IVX	
HWV68_11055	ENOG4106PTB	DnaB-like helicase C terminal domain
HWV68_11065	ENOG41088HM	
HWV68_11070	ENOG4106YR8	
HWV68_11100	ENOG4105K7W	phage-related replication protein
HWV68_11115	ENOG4108RAV	Conserved protein
HWV68_11120	ENOG4108J9Q	DNA ligase
HWV68_11175	ENOG4105GJD	protein, conserved in bacteria
HWV68_11205	ENOG4108ZUE	Phage regulatory protein rha
HWV68_11300	ENOG4107D0N	
HWV68_11315	ENOG4106HHG	
HWV68_11350	ENOG4106J6E	
HWV68_11355	ENOG4107NTZ	
HWV68_11360	ENOG41063R6	
HWV68_11370	ENOG4108NE4	
HWV68_11395	ENOG41067QW	Transcriptional regulator
HWV68_11405	ENOG4105ZUG	
HWV68_11410	ENOG4105K70	DNA-binding protein
HWV68_11425	ENOG4106QVS	
HWV68_11520	ENOG41068G1	
HWV68_11575	ENOG4105E4C	Lytic transglycosylase catalytic
HWV68_11595	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
HWV68_11600	ENOG4105MYH	
HWV68_11610	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
HWV68_11630	ENOG4107R0E	Glycosyl transferase, family 2
HWV68_11655	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HWV68_11685	ENOG4105UA4	acetyltransferase
HWV68_11695	ENOG41090AA	
HWV68_11700	ENOG4106BHF	
HWV68_11720	ENOG4107Y9E	nuclease
HWV68_11730	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
HWV68_11745	ENOG4106RPI	
HWV68_11760	ENOG4105C5E	polysaccharide biosynthesis protein
HWV68_11765	ENOG4105E0X	reductase
HWV68_11770	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HWV68_11790	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
HWV68_11795	ENOG41090WU	lipolytic protein G-D-S-L family
HWV68_11800	ENOG4108KF3	Electron transport protein SCO1 SenC
HWV68_11810	ENOG4105C7B	Threonine dehydratase
HWV68_11820	ENOG4108UT2	hemolysin iii
HWV68_11830	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HWV68_11835	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HWV68_11850	ENOG4107YX5	Pfam:DUF548
HWV68_11855	ENOG4108Y6J	UPF0403 protein
HWV68_11860	ENOG4105C01	Dihydroxy-acid dehydratase
HWV68_11875	ENOG4108V06	Glutathione peroxidase
HWV68_11880	ENOG4105CVG	Homoserine O-transsuccinylase
HWV68_11925	ENOG41081VK	Ribonuclease
HWV68_11950	ENOG410890F	Dynamin family
HWV68_11965	ENOG41065KQ	synthase
HWV68_11970	ENOG4105C2W	permease
HWV68_11975	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
HWV68_11980	ENOG4105CTD	carboxy-peptidase
HWV68_11985	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
HWV68_11990	ENOG4108UHU	Aldolase
HWV68_11995	ENOG4105D7K	pfkb domain protein
HWV68_12000	ENOG4108M60	Transcriptional regulator
HWV68_12010	ENOG4105CHR	reductase
HWV68_12015	ENOG4105DVT	helicase
HWV68_12030	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HWV68_12045	ENOG4108UKS	UPF0398 protein
HWV68_12060	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
HWV68_12065	ENOG4108I5C	dEAD DEAH box helicase
HWV68_12115	ENOG4105BZ4	penicillin-binding protein
HWV68_12125	ENOG4105CSM	endonuclease III
HWV68_12135	ENOG4105C5S	asparaginyl-tRNA synthetase
HWV68_12140	ENOG4105CHM	Aminotransferase
HWV68_12150	ENOG4105YAC	
HWV68_12155	ENOG4105DVT	helicase
HWV68_12160	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HWV68_12165	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HWV68_12170	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HWV68_12175	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HWV68_12180	ENOG4105DJ0	Poly(A) Polymerase
HWV68_12185	ENOG4105CPK	Glycosyl transferase (Group 1
HWV68_12190	ENOG4105FJR	Lmbe family
HWV68_12195	ENOG4108Z5K	methylglyoxal synthase
HWV68_12200	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HWV68_12205	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
HWV68_12210	ENOG4108JYZ	YitT family
HWV68_12230	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HWV68_12250	ENOG41068YB	TPR repeat-containing protein
HWV68_12255	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HWV68_12265	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HWV68_12275	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HWV68_12280	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HWV68_12290	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HWV68_12295	ENOG4105CRQ	synthase (Component I)
HWV68_12300	ENOG4105KHN	chorismate mutase
HWV68_12305	ENOG4105D49	3-dehydroquinate synthase
HWV68_12310	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HWV68_12315	ENOG4105BZU	Histidine kinase
HWV68_12320	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HWV68_12325	ENOG4105EAH	synthase
HWV68_12330	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HWV68_12335	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
HWV68_12345	ENOG4105EUJ	GTP cyclohydrolase i
HWV68_12350	ENOG4105K70	DNA-binding protein
HWV68_12355	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
HWV68_12370	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HWV68_12375	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HWV68_12380	ENOG41065D1	
HWV68_12385	ENOG4105S2F	
HWV68_12400	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HWV68_12405	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HWV68_12410	ENOG4105CAT	Cytidine monophosphate kinase
HWV68_12425	ENOG4105MSI	germination protein ypeb
HWV68_12435	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
HWV68_12440	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
HWV68_12455	ENOG4107RGJ	metallophosphoesterase
HWV68_12470	ENOG4105I7S	Abortive infection protein
HWV68_12475	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HWV68_12480	ENOG4105T7X	
HWV68_12490	ENOG4108SAX	Membrane
HWV68_12495	ENOG4108JQ1	Dehydrogenase
HWV68_12500	ENOG4105FF2	Type I DHQase
HWV68_12515	ENOG4105BZU	Histidine kinase
HWV68_12520	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HWV68_12525	ENOG4105CRE	cytochrome C
HWV68_12530	ENOG4107TWT	Cytochrome c biogenesis protein
HWV68_12540	ENOG4105FE9	pseudouridine synthase
HWV68_12550	ENOG4108JIC	nucleoside recognition domain protein
HWV68_12555	ENOG4105DZ1	carboxypeptidase
HWV68_12565	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HWV68_12570	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HWV68_12585	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HWV68_12590	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HWV68_12595	ENOG4108R6K	riboflavin synthase, subunit alpha
HWV68_12600	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HWV68_12610	ENOG4105C3F	Signal peptidase i
HWV68_12620	ENOG4105VES	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HWV68_12635	ENOG4107ZE5	PPIases accelerate the folding of proteins
HWV68_12640	ENOG4105PTM	secreted protein
HWV68_12645	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HWV68_12655	ENOG4105G6R	Stage v sporulation protein ae
HWV68_12665	ENOG4105CZ3	stage V sporulation protein ad
HWV68_12670	ENOG41090VF	Stage v sporulation protein ac
HWV68_12685	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HWV68_12690	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
HWV68_12695	ENOG41082AN	stage II sporulation protein
HWV68_12700	ENOG4105DZ1	carboxypeptidase
HWV68_12705	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
HWV68_12710	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HWV68_12715	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HWV68_12725	ENOG4105I3K	Ferric uptake regulator, Fur family
HWV68_12730	ENOG4105MZ9	stage II sporulation protein m
HWV68_12745	ENOG4105DFD	Na H antiporter
HWV68_12750	ENOG4108IJ0	Aspartate ammonia-lyase
HWV68_12755	ENOG4105HDK	L-asparaginase
HWV68_12760	ENOG4108IMY	Transcriptional regulator
HWV68_12770	ENOG4108YZ4	nudix hydrolase
HWV68_12780	ENOG4105CPC	Aldo Keto reductase
HWV68_12800	ENOG4106HZJ	
HWV68_12805	ENOG4105RHY	Pfam:UPF0157
HWV68_12810	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
HWV68_12815	ENOG4108XET	gCN5-related N-acetyltransferase
HWV68_12825	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HWV68_12835	ENOG4105E5W	Transporter
HWV68_12845	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
HWV68_12860	ENOG4108IXY	short-chain dehydrogenase reductase
HWV68_12865	ENOG41069FQ	Metallo-beta-lactamase superfamily
HWV68_12870	ENOG4105II7	pyrroline-5-carboxylate reductase
HWV68_12880	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HWV68_12895	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HWV68_12900	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HWV68_12905	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HWV68_12910	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HWV68_12920	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
HWV68_12925	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
HWV68_12930	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HWV68_12935	ENOG4108HNZ	carboxyl transferase
HWV68_12940	ENOG4108ZVT	methylmalonyl-coA epimerase
HWV68_12950	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
HWV68_12955	ENOG4108QEG	Membrane
HWV68_12960	ENOG4105CDA	abc transporter atp-binding protein
HWV68_12965	ENOG4105E5Q	amino acid AbC transporter
HWV68_12970	ENOG4108HW3	(ABC) transporter
HWV68_12975	ENOG4108Y6J	UPF0403 protein
HWV68_12980	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
HWV68_12995	ENOG4105C7S	Dehydrogenase
HWV68_13000	ENOG4105CPP	Dehydrogenase, E1 component
HWV68_13015	ENOG4105CKM	Branched-chain carboxylic acid kinase
HWV68_13020	ENOG4107RDP	Dehydrogenase
HWV68_13030	ENOG4108JUB	Transcriptional regulator
HWV68_13035	ENOG4106CCJ	Protein of unknown function (DUF2627)
HWV68_13040	ENOG4105CR4	methylisocitrate lyase
HWV68_13045	ENOG4105DXD	2-methylcitrate dehydratase
HWV68_13055	ENOG4105C1G	acyl-Coa dehydrogenase
HWV68_13060	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HWV68_13070	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HWV68_13075	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HWV68_13090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HWV68_13095	ENOG4107QQR	Sporulation
HWV68_13100	ENOG4105S1Z	Stage IV sporulation protein B
HWV68_13105	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HWV68_13110	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HWV68_13115	ENOG4105DX0	Hemolysin A
HWV68_13125	ENOG4105CTB	Polyprenyl synthetase
HWV68_13130	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HWV68_13135	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HWV68_13140	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HWV68_13145	ENOG4105M7K	Involved in the transcription termination process (By similarity)
HWV68_13150	ENOG4108ZSR	alkaline shock protein
HWV68_13155	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HWV68_13175	ENOG410644B	Stage III sporulation protein af
HWV68_13185	ENOG4105KQ4	Stage iii sporulation protein ad
HWV68_13190	ENOG4108CQH	stage III sporulation protein AC
HWV68_13195	ENOG4105KR5	Stage iii sporulation protein
HWV68_13200	ENOG4105CD2	stage iii sporulation protein aa
HWV68_13210	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HWV68_13215	ENOG4105DC7	peptidase M24
HWV68_13220	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HWV68_13230	ENOG4105CBJ	Metal-dependent enzyme
HWV68_13245	ENOG4105KST	dependent repressor
HWV68_13250	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
HWV68_13255	ENOG4105WZW	rhodanese family
HWV68_13260	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HWV68_13265	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HWV68_13270	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HWV68_13275	ENOG4105C0D	helicase
HWV68_13290	ENOG4108IMY	Transcriptional regulator
HWV68_13300	ENOG4105VFR	signal peptidase
HWV68_13360	ENOG4105C37	(CBS) domain
HWV68_13385	ENOG4105C5X	domain protein
HWV68_13410	ENOG4105E0M	Sulfatase
HWV68_13425	ENOG4107ZXI	Rhomboid family
HWV68_13435	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HWV68_13460	ENOG41068DG	YceG-like family
HWV68_13465	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HWV68_13470	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HWV68_13475	ENOG4105E2Z	phosphate ABC transporter (Permease
HWV68_13480	ENOG4105C8U	phosphate abc transporter
HWV68_13485	ENOG4105CVA	phosphate
HWV68_13490	ENOG4107RF6	penicillin-binding protein
HWV68_13500	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HWV68_13505	ENOG4105SXS	Protein of unknown function (DUF456)
HWV68_13525	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HWV68_13530	ENOG41063Y9	
HWV68_13535	ENOG4108U5J	'-nucleotidase
HWV68_13540	ENOG4105N80	Ferric uptake regulator, Fur family
HWV68_13545	ENOG4108JYZ	YitT family
HWV68_13550	ENOG41069ZM	Protein of unknown function (DUF2624)
HWV68_13555	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HWV68_13570	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HWV68_13575	ENOG4105EGD	dinuclear metal center protein, YbgI family
HWV68_13590	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HWV68_13595	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HWV68_13600	ENOG41082VT	Uncharacterized BCR, YaiI/YqxD family COG1671
HWV68_13605	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HWV68_13615	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HWV68_13620	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HWV68_13625	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
HWV68_13635	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HWV68_13640	ENOG4105KG3	cytidine deaminase
HWV68_13645	ENOG4107YR5	Diacylglycerol kinase
HWV68_13650	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HWV68_13655	ENOG4105CTJ	Metal Dependent Phosphohydrolase
HWV68_13660	ENOG4105C9A	Phoh family
HWV68_13665	ENOG4105EI1	sporulation protein yqfd
HWV68_13670	ENOG41068P3	sporulation protein YqfC
HWV68_13680	ENOG4105DI5	UPF0365 protein
HWV68_13685	ENOG4105F7J	membrane-bound serine protease
HWV68_13690	ENOG4105KTH	gatB Yqey
HWV68_13705	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HWV68_13710	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HWV68_13715	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HWV68_13725	ENOG4105CFG	Acts as a chaperone (By similarity)
HWV68_13730	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HWV68_13735	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HWV68_13740	ENOG4105CSA	Coproporphyrinogen iii oxidase
HWV68_13745	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HWV68_13755	ENOG4108ZRV	stage ii sporulation protein p
HWV68_13760	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
HWV68_13765	ENOG41082YS	Binds directly to 16S ribosomal RNA
HWV68_13770	ENOG4105TQK	DNA polymerase iii, delta' subunit
HWV68_13785	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HWV68_13790	ENOG4108UK2	deaminase
HWV68_13795	ENOG4105KQC	Competence protein
HWV68_13805	ENOG4108D32	Methyltransferase
HWV68_13815	ENOG4108WF2	Metal Dependent Phosphohydrolase
HWV68_13820	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HWV68_13825	ENOG410812S	Rna-binding protein
HWV68_13830	ENOG4105E2X	shikimate dehydrogenase
HWV68_13835	ENOG4105CQW	ribosome biogenesis GTPase YqeH
HWV68_13840	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HWV68_13855	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
HWV68_13860	ENOG41080BT	SNARE associated Golgi
HWV68_13875	ENOG4105WFK	nuclease
HWV68_13885	ENOG4107Y5K	Resolvase
HWV68_13890	ENOG4108UXE	Protein tyrosine phosphatase
HWV68_13895	ENOG4105D6J	arsenicaL-resistance protein
HWV68_13900	ENOG4108YZ3	Glyoxalase Bleomycin resistance protein (Dioxygenase
HWV68_13905	ENOG41085FC	arsR family transcriptional regulator
HWV68_13935	ENOG41064HX	Suppressor of fused protein (SUFU)
HWV68_13955	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
HWV68_13990	ENOG410906S	phage-like element pbsx protein xkdt
HWV68_13995	ENOG41066EA	baseplate J family protein
HWV68_14000	ENOG4105MFU	Protein of unknown function (DUF2634)
HWV68_14010	ENOG4105X7F	
HWV68_14015	ENOG4108WZM	domain protein
HWV68_14020	ENOG4108FKH	Transglycosylase SLT domain
HWV68_14030	ENOG4105MTC	XkdN-like protein
HWV68_14045	ENOG4105FR7	XkdM protein, phage-like element PBSX
HWV68_14050	ENOG4105PQS	phage protein
HWV68_14065	ENOG41060SN	
HWV68_14100	ENOG4106CGH	Phage Mu protein F like protein
HWV68_14105	ENOG4108MDF	Phage Portal Protein
HWV68_14110	ENOG4105IG6	Phage terminase, large subunit
HWV68_14130	ENOG4106129	
HWV68_14140	ENOG4105QBX	endodeoxyribonuclease RusA
HWV68_14160	ENOG4108PNI	recT protein
HWV68_14165	ENOG4108NF7	phage-type endonuclease
HWV68_14195	ENOG4106A7E	Transcriptional regulator
HWV68_14200	ENOG41067QW	Transcriptional regulator
HWV68_14210	ENOG4105KR8	Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HWV68_14245	ENOG4108SWU	Histidine kinase
HWV68_14250	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HWV68_14255	ENOG4105DHF	Membrane
HWV68_14265	ENOG4108UYN	gCN5-related N-acetyltransferase
HWV68_14270	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HWV68_14275	ENOG41068VA	
HWV68_14280	ENOG41087NI	Sulfite exporter TauE/SafE
HWV68_14285	ENOG4105VFE	sira family
HWV68_14290	ENOG4107TPS	domain protein
HWV68_14300	ENOG4105VFE	sira family
HWV68_14305	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
HWV68_14310	ENOG4105XTG	Pfam:DUF156
HWV68_14315	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
HWV68_14325	ENOG41090E6	transcriptional regulator MERR family
HWV68_14340	ENOG4105C37	(CBS) domain
HWV68_14355	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
HWV68_14360	ENOG4105H3G	oxidoreductase
HWV68_14365	ENOG4105PGM	cation diffusion facilitator family transporter
HWV68_14370	ENOG41090U3	tautomerase
HWV68_14390	ENOG4105KMT	branched-chain amino acid
HWV68_14395	ENOG4108UMN	azlc family
HWV68_14400	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
HWV68_14405	ENOG41067XF	inhibitor
HWV68_14425	ENOG41064BW	Protein of unknown function (DUF2568)
HWV68_14440	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
HWV68_14445	ENOG4105EA8	2-Nitropropane dioxygenase
HWV68_14450	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HWV68_14470	ENOG4108MEK	Metal-binding protein YodA
HWV68_14475	ENOG410904A	RNA polymerase
HWV68_14480	ENOG4105CPC	Aldo Keto reductase
HWV68_14490	ENOG4108KAM	Transcriptional regulator
HWV68_14495	ENOG4105C7F	AcnD-accessory protein PrpF
HWV68_14500	ENOG41083Q9	chitosanase
HWV68_14505	ENOG4105X5K	response regulator receiver protein
HWV68_14510	ENOG4108VQT	Alpha beta hydrolase fold protein
HWV68_14515	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
HWV68_14520	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
HWV68_14530	ENOG4105Z0X	Glyoxalase Bleomycin resistance protein (Dioxygenase
HWV68_14540	ENOG4105PGS	Spore coat protein
HWV68_14545	ENOG4105E2A	Dehydrogenase
HWV68_14560	ENOG4105VUF	Transcriptional regulator
HWV68_14570	ENOG4105DQ4	alcohol dehydrogenase
HWV68_14575	ENOG4108Z0Z	intracellular protease Pfpi family
HWV68_14580	ENOG4108HKT	sucrose-6-phosphate hydrolase
HWV68_14585	ENOG4105F3R	pts system mannose fructose sorbose family iid
HWV68_14590	ENOG4105ETZ	PTS System
HWV68_14595	ENOG4108IQ3	PTS system
HWV68_14600	ENOG4105YHU	PTS system
HWV68_14605	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HWV68_14615	ENOG4105C85	amino acid
HWV68_14620	ENOG4105N14	lysine exporter protein LysE YggA
HWV68_14625	ENOG4108NGU	Transcriptional regulator
HWV68_14630	ENOG4105JVQ	RNA Polymerase
HWV68_14635	ENOG4108P49	AntiSigma factor
HWV68_14640	ENOG4105EXC	Acyl-transferase
HWV68_14645	ENOG4105WDR	
HWV68_14650	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HWV68_14655	ENOG41082JN	Transcriptional regulator
HWV68_14675	ENOG4105TMB	Formate nitrite transporter
HWV68_14680	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
HWV68_14685	ENOG4108JB9	formate dehydrogenase
HWV68_14700	ENOG4105C28	cystathionine
HWV68_14715	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
HWV68_14730	ENOG4107XRG	penicillin-binding protein
HWV68_14735	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HWV68_14740	ENOG4105DBI	uridine monophosphokinase
HWV68_14745	ENOG4105CFP	Peptidase U32
HWV68_14750	ENOG4105XYU	peptidase (U32 family)
HWV68_14760	ENOG4105HHA	aminodeoxychorismate lyase
HWV68_14765	ENOG4105VPH	UPF0473 protein
HWV68_14770	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HWV68_14775	ENOG4105VBH	UPF0297 protein
HWV68_14780	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HWV68_14785	ENOG4105C02	permease
HWV68_14790	ENOG4105CDA	abc transporter atp-binding protein
HWV68_14795	ENOG4105CT1	(ABC) transporter
HWV68_14800	ENOG4105EAD	ABC transporter
HWV68_14805	ENOG4105DRP	amino acid AbC transporter
HWV68_14815	ENOG41060CR	
HWV68_14825	ENOG4105C7H	Helicase, RecD TraA family
HWV68_14835	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HWV68_14840	ENOG4105C3J	Cysteine desulfurase
HWV68_14850	ENOG4105D1H	recombination factor protein RarA
HWV68_14855	ENOG4105CUZ	uba thif-type nad fad binding protein
HWV68_14865	ENOG4105C9M	aspartyl-trna synthetase
HWV68_14870	ENOG4105CUT	histidyl-tRNA synthetase
HWV68_14880	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HWV68_14890	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HWV68_14895	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HWV68_14900	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HWV68_14905	ENOG41067VP	Protein of unknown function (DUF1049)
HWV68_14910	ENOG4105NCW	Trka-c domain protein
HWV68_14915	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HWV68_14925	ENOG4105CKP	Polysaccharide Biosynthesis Protein
HWV68_14930	ENOG4108QG2	Membrane
HWV68_14935	ENOG4105NAP	
HWV68_14940	ENOG4105VIE	preprotein translocase, subunit YajC
HWV68_14945	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HWV68_14950	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HWV68_14955	ENOG41061AI	Protein of unknown function (DUF2905)
HWV68_14960	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HWV68_14965	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HWV68_14975	ENOG4105IE8	Alpha-ketoglutarate permease
HWV68_14980	ENOG4105CK5	oxidoreductase
HWV68_15005	ENOG4105BZG	amino acid carrier protein
HWV68_15010	ENOG4105CDY	transcriptional regulatory protein
HWV68_15020	ENOG4106678	morphogenetic protein associated with SpoVID
HWV68_15025	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HWV68_15030	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HWV68_15035	ENOG4108IYU	L-aspartate oxidase
HWV68_15050	ENOG4105CQC	Prephenate dehydratase
HWV68_15055	ENOG41090I5	UPF0735 ACT domain-containing protein
HWV68_15060	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HWV68_15075	ENOG4105K46	50S ribosomal protein l27
HWV68_15080	ENOG4105X36	(ribosomal) protein
HWV68_15085	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HWV68_15100	ENOG4107QMS	site-determining protein
HWV68_15105	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HWV68_15110	ENOG4105YHC	Rod shape-determining protein MreD
HWV68_15120	ENOG4105DFF	Rod shape-determining protein mreb
HWV68_15125	ENOG4105W5Q	DNA repair protein (RadC
HWV68_15130	ENOG4108Z03	MAF-like protein
HWV68_15140	ENOG4106A3R	peptidase
HWV68_15145	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HWV68_15150	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HWV68_15160	ENOG4106AR7	Spore coat protein
HWV68_15165	ENOG41068KH	stage VI sporulation protein D
HWV68_15170	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HWV68_15175	ENOG4105D52	delta-aminolevulinic acid dehydratase
HWV68_15185	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HWV68_15195	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HWV68_15205	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HWV68_15210	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HWV68_15215	ENOG4108IUQ	atp-dependent protease
HWV68_15220	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HWV68_15225	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HWV68_15235	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HWV68_15240	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HWV68_15245	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HWV68_15250	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HWV68_15255	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HWV68_15260	ENOG4108ZP8	Acetolactate synthase small subunit
HWV68_15265	ENOG4105C7K	acetolactate synthase
HWV68_15275	ENOG4105I4A	GCN5-related N-acetyltransferase
HWV68_15280	ENOG4107KM7	Heat induced stress protein YflT
HWV68_15290	ENOG4105M59	Phosphodiesterase, mj0936 family
HWV68_15295	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HWV68_15300	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HWV68_15305	ENOG4108XJQ	germination protein
HWV68_15310	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HWV68_15315	ENOG41067TZ	transcriptional regulator, MarR family
HWV68_15320	ENOG4105PFC	Transcriptional regulator
HWV68_15330	ENOG4105E33	succinate dehydrogenase
HWV68_15340	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
HWV68_15350	ENOG4105CFH	Aspartokinase
HWV68_15355	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HWV68_15360	ENOG4105K63	Thioredoxin
HWV68_15365	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HWV68_15370	ENOG4105C10	Electron transfer flavoprotein
HWV68_15375	ENOG4105BZJ	Electron transfer flavoprotein
HWV68_15380	ENOG41060WC	Enoyl-CoA hydratase
HWV68_15385	ENOG4107Z3H	Transcriptional regulator, TetR family
HWV68_15390	ENOG4105CEY	Amp-dependent synthetase and ligase
HWV68_15400	ENOG4105C98	muts2 protein
HWV68_15405	ENOG4105DCG	PHP domain protein
HWV68_15420	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HWV68_15425	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HWV68_15430	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HWV68_15440	ENOG4108RWN	rrna methyltransferase
HWV68_15445	ENOG41067MF	small acid-soluble spore protein
HWV68_15455	ENOG4105CQB	FAD linked oxidase domain protein
HWV68_15460	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HWV68_15480	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HWV68_15485	ENOG4105DRS	transport system, permease
HWV68_15500	ENOG4108MDK	Dehydrogenase
HWV68_15510	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
HWV68_15515	ENOG4105EF1	ribulokinase
HWV68_15525	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
HWV68_15530	ENOG4105CN9	Peptidase m42 family protein
HWV68_15540	ENOG410696E	Membrane
HWV68_15545	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HWV68_15550	ENOG4105VJV	50s ribosomal protein L35
HWV68_15555	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HWV68_15565	ENOG41067MG	lrgb family
HWV68_15575	ENOG4105DY9	regulatoR
HWV68_15580	ENOG4108HRK	Histidine kinase
HWV68_15590	ENOG4105C22	threonyL-tRNA synthetase
HWV68_15595	ENOG4108TDW	sporulation protein YtxC
HWV68_15615	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HWV68_15620	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HWV68_15625	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HWV68_15630	ENOG4105KVH	Transcriptional regulator
HWV68_15635	ENOG4105F27	Major Facilitator
HWV68_15640	ENOG4105CV8	reductase
HWV68_15645	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HWV68_15655	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HWV68_15660	ENOG4105C2M	dna polymerase I
HWV68_15665	ENOG4105BZU	Histidine kinase
HWV68_15670	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HWV68_15675	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HWV68_15680	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HWV68_15685	ENOG4105BZN	citrate synthase
HWV68_15695	ENOG4108REF	Sporulation integral membrane protein ytvi
HWV68_15700	ENOG4105FS0	cytoplasmic membrane protein
HWV68_15705	ENOG4105CA9	Pyruvate kinase
HWV68_15710	ENOG4105CTQ	phosphohexokinase
HWV68_15720	ENOG4108IEY	Carboxyl transferase domain
HWV68_15725	ENOG4105C6K	Malic enzyme
HWV68_15730	ENOG4105C0B	DNA polymerase III (alpha subunit)
HWV68_15735	ENOG4105VV2	
HWV68_15745	ENOG4106EVM	
HWV68_15750	ENOG4105SFS	phosphoesterase RecJ domain protein
HWV68_15765	ENOG410635A	Membrane
HWV68_15770	ENOG4105CH2	amidohydrolase
HWV68_15790	ENOG4105DEN	Luciferase family
HWV68_15795	ENOG4105CDA	abc transporter atp-binding protein
HWV68_15820	ENOG4108XSB	acetyltransferase, (GNAT) family
HWV68_15825	ENOG4108KSA	LysR family transcriptional regulator
HWV68_15830	ENOG4105E8R	UPF0173 metal-dependent hydrolase
HWV68_15840	ENOG4105CH7	arginosuccinase
HWV68_15845	ENOG4105CDH	Citrulline--aspartate ligase
HWV68_15850	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
HWV68_15855	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HWV68_15870	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HWV68_15875	ENOG4105KBJ	sporulation protein ytfj
HWV68_15885	ENOG4105VK3	rdd domain containing protein
HWV68_15890	ENOG4105D07	Signal peptide peptidase, SppA
HWV68_15895	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HWV68_15900	ENOG4105EFZ	amidohydrolase
HWV68_15905	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HWV68_15940	ENOG4105U5Y	Transcriptional regulator
HWV68_15950	ENOG4105BZU	Histidine kinase
HWV68_15955	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HWV68_15960	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HWV68_15970	ENOG4105F1V	Acetoin utilization protein
HWV68_15975	ENOG4105W87	Cbs domain
HWV68_15980	ENOG4105DGU	Histone deacetylase
HWV68_15985	ENOG4105ER2	Ompa motb domain protein
HWV68_15990	ENOG4107R0U	MotA TolQ exbB proton channel
HWV68_15995	ENOG4105ETE	Transcriptional regulator (LacI family
HWV68_16000	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HWV68_16020	ENOG4105DFU	Cell wall formation (By similarity)
HWV68_16030	ENOG4108VDD	TRNA binding domain protein
HWV68_16050	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
HWV68_16065	ENOG4105C6K	Malic enzyme
HWV68_16070	ENOG4105C8F	Beta-lactamase domain protein
HWV68_16075	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HWV68_16085	ENOG4108V15	phosphotransferase enzyme family
HWV68_16090	ENOG4108IUM	Glycogen debranching enzyme
HWV68_16105	ENOG4107F58	2'-5' rna ligase
HWV68_16110	ENOG4105C6T	cysteine synthase
HWV68_16115	ENOG4107QSE	Dipeptidase
HWV68_16120	ENOG4105C7N	Xanthine uracil vitamin C permease
HWV68_16135	ENOG4105YW5	deoR family transcriptional regulator
HWV68_16150	ENOG4105CBX	hi0933 family
HWV68_16155	ENOG4105C94	Transporter
HWV68_16165	ENOG4105MU9	integral membrane protein
HWV68_16170	ENOG4105DDC	Oxidoreductase domain protein
HWV68_16180	ENOG4105F5H	Glycosyl Hydrolase Family 88
HWV68_16190	ENOG41075H3	AraC family transcriptional regulator
HWV68_16200	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HWV68_16210	ENOG4106A3M	Cytochrome p-450
HWV68_16215	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HWV68_16220	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HWV68_16225	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HWV68_16230	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HWV68_16235	ENOG4108W8G	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity)
HWV68_16240	ENOG4105NTD	Inherit from COG: Hydrolase
HWV68_16270	ENOG41085GJ	domain protein
HWV68_16275	ENOG4105C8T	Leucyl-tRNA synthetase
HWV68_16285	ENOG4105BZU	Histidine kinase
HWV68_16290	ENOG410605W	Major Facilitator
HWV68_16295	ENOG4106UBQ	
HWV68_16305	ENOG4105C19	ABC transporter
HWV68_16310	ENOG4105EWM	Histidine kinase
HWV68_16320	ENOG4107R34	abc transporter permease protein
HWV68_16325	ENOG4105C19	ABC transporter
HWV68_16340	ENOG4105DVE	abc transporter atp-binding protein
HWV68_16345	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HWV68_16360	ENOG4105N5T	Radical SAM Protein
HWV68_16375	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
HWV68_16380	ENOG4108Z0R	Transferase
HWV68_16385	ENOG4105C85	amino acid
HWV68_16390	ENOG4105CAQ	asparagine synthetase
HWV68_16395	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HWV68_16400	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HWV68_16415	ENOG4105D2X	ABC transporter substrate-binding protein
HWV68_16425	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
HWV68_16440	ENOG4108RMU	ferritin dps family protein
HWV68_16455	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HWV68_16460	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HWV68_16465	ENOG4108V2W	Carbonate dehydratase
HWV68_16490	ENOG4105CC5	ABC transporter
HWV68_16495	ENOG4105CC5	ABC transporter
HWV68_16500	ENOG4105DIK	(ABC) transporter
HWV68_16505	ENOG4105DSE	periplasmic solute binding protein
HWV68_16510	ENOG4105DTQ	mandelate racemase muconate lactonizing
HWV68_16515	ENOG4105CEY	Amp-dependent synthetase and ligase
HWV68_16520	ENOG4108IPT	Naphthoate synthase
HWV68_16525	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HWV68_16530	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HWV68_16535	ENOG4105E4F	Isochorismate synthase
HWV68_16555	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HWV68_16560	ENOG4107SBE	Glycosyl transferase (Group 1
HWV68_16575	ENOG4107SBE	Glycosyl transferase (Group 1
HWV68_16580	ENOG4108KS4	Spore coat protein
HWV68_16595	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HWV68_16605	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HWV68_16735	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
HWV68_16740	ENOG4105VRR	gCN5-related N-acetyltransferase
HWV68_16745	ENOG4105DZ6	Band 7 protein
HWV68_16755	ENOG4106DF1	
HWV68_16760	ENOG4108VNY	MOSC domain protein
HWV68_16765	ENOG4108JB8	alcohol dehydrogenase
HWV68_16775	ENOG4105TRT	Transcriptional regulator
HWV68_16790	ENOG4105CZN	Potassium uptake protein
HWV68_16795	ENOG4107I77	yiaA/B two helix domain
HWV68_16800	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HWV68_16820	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HWV68_16830	ENOG4105EE0	oxidoreductase
HWV68_16835	ENOG4105DKG	l-rhamnose isomerase
HWV68_16840	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
HWV68_16845	ENOG4105DET	Rhamnulokinase
HWV68_16850	ENOG4105E98	transcriptional regulator DeoR family
HWV68_16860	ENOG4105C8Q	Methyl-accepting chemotaxis
HWV68_16865	ENOG4105C8Q	Methyl-accepting chemotaxis
HWV68_16870	ENOG4105C8Q	Methyl-accepting chemotaxis
HWV68_16875	ENOG4105C8Q	Methyl-accepting chemotaxis
HWV68_16890	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HWV68_16905	ENOG4105C37	(CBS) domain
HWV68_16920	ENOG4107PBV	potassium channel
HWV68_16925	ENOG4107PBV	potassium channel
HWV68_16940	ENOG4107QYV	phosphohexose isomerase
HWV68_16950	ENOG4107QW4	alcohol dehydrogenase
HWV68_16955	ENOG4105WG9	Conserved Protein
HWV68_16965	ENOG4105CHM	Aminotransferase
HWV68_16970	ENOG4108ZB6	transcriptional regulator AsnC family
HWV68_16975	ENOG4108MUZ	hydrolase
HWV68_16985	ENOG4105C87	Aminotransferase class I and II
HWV68_16990	ENOG4108HGU	Histidine kinase
HWV68_16995	ENOG4105Y38	Kinase-associated protein B
HWV68_17010	ENOG4105BZ4	penicillin-binding protein
HWV68_17015	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
HWV68_17030	ENOG4108MRH	transcriptional regulatory protein
HWV68_17035	ENOG4105DIH	basic membrane
HWV68_17040	ENOG4108JQ9	ABC transporter
HWV68_17045	ENOG4105UIB	(ABC) transporter
HWV68_17065	ENOG4105D65	subunit l
HWV68_17070	ENOG4105HC0	Na H antiporter
HWV68_17075	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HWV68_17080	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HWV68_17085	ENOG4105SC1	monovalent cation H antiporter subunit E
HWV68_17095	ENOG4105KJM	monovalent cation h antiporter subunit g
HWV68_17100	ENOG4105KA0	thioesterase Superfamily protein
HWV68_17110	ENOG4105BZU	Histidine kinase
HWV68_17140	ENOG4105D58	Diguanylate phosphodiesterase
HWV68_17145	ENOG4105DAP	Nicotinate phosphoribosyltransferase
HWV68_17170	ENOG4105C02	permease
HWV68_17190	ENOG410904N	short-chain dehydrogenase reductase
HWV68_17225	ENOG4108K8K	Transcriptional regulator
HWV68_17230	ENOG4105DCF	alanine dehydrogenase
HWV68_17240	ENOG4105WQT	MbtH domain protein
HWV68_17245	ENOG4105CEY	Amp-dependent synthetase and ligase
HWV68_17250	ENOG4105WQI	isochorismatase
HWV68_17255	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HWV68_17260	ENOG4105E4F	Isochorismate synthase
HWV68_17265	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HWV68_17270	ENOG4105NIV	Esterase
HWV68_17290	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HWV68_17300	ENOG41069ER	domain protein
HWV68_17315	ENOG4105CEP	NADH dehydrogenase
HWV68_17320	ENOG4105CAY	ferredoxin--nadp reductase
HWV68_17340	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
HWV68_17345	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HWV68_17360	ENOG4105ZKE	UPF0349 protein
HWV68_17375	ENOG41083MR	nifu domain-containing protein
HWV68_17380	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HWV68_17385	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HWV68_17390	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
HWV68_17395	ENOG4105D6E	homoserine dehydrogenase
HWV68_17405	ENOG4108W5N	phosphatidylglycerophosphatase a
HWV68_17410	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HWV68_17420	ENOG4105MMD	transcriptional regulator
HWV68_17425	ENOG4106EGE	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HWV68_17430	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HWV68_17435	ENOG4105FAA	peptidase M23
HWV68_17440	ENOG4108YTE	sporulation protein YunB
HWV68_17445	ENOG4105KZD	Domain of unknown function (DUF1805)
HWV68_17450	ENOG4107R8B	5'-nucleotidase
HWV68_17460	ENOG4105I3N	Conserved Protein
HWV68_17470	ENOG4105CD3	dihydroorotase
HWV68_17475	ENOG4105G9B	Transcriptional regulator
HWV68_17490	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
HWV68_17495	ENOG4105VT2	5-hydroxyisourate hydrolase
HWV68_17505	ENOG4107YV9	domain protein
HWV68_17510	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HWV68_17525	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
HWV68_17530	ENOG4105C5R	Aminotransferase
HWV68_17545	ENOG4108K8S	endonuclease I
HWV68_17550	ENOG4108IJ9	(ABC) transporter
HWV68_17555	ENOG4105FDP	GntR family transcriptional regulator
HWV68_17560	ENOG4108KPW	sugar kinase
HWV68_17565	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
HWV68_17570	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HWV68_17575	ENOG4105XN3	extracellular solute-binding protein family 1
HWV68_17580	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
HWV68_17585	ENOG4105PKS	Excinuclease abc c subunit domain protein
HWV68_17590	ENOG4107VFR	oxidoreductase
HWV68_17605	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
HWV68_17610	ENOG4105NPE	arsR family transcriptional regulator
HWV68_17615	ENOG4105DIW	FeS assembly protein SUFB
HWV68_17620	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HWV68_17625	ENOG4105C9B	Cysteine desulfurase
HWV68_17630	ENOG4105JRK	feS assembly protein SufD
HWV68_17635	ENOG4105C3K	feS assembly ATPase SufC
HWV68_17650	ENOG4105D01	(LipO)protein
HWV68_17655	ENOG4108UMI	ABC transporter, permease
HWV68_17660	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HWV68_17685	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HWV68_17690	ENOG41080E8	Transcriptional regulator, Spx MgsR family
HWV68_17695	ENOG4105C1G	acyl-Coa dehydrogenase
HWV68_17700	ENOG4105CHU	acetyl-coa acetyltransferase
HWV68_17730	ENOG41067TZ	transcriptional regulator, MarR family
HWV68_17735	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HWV68_17740	ENOG4105MDS	4-oxalocrotonate tautomerase
HWV68_17750	ENOG4105EGI	Transcriptional regulator
HWV68_17760	ENOG4105E0A	ABC, transporter
HWV68_17775	ENOG4105E1F	short-chain dehydrogenase reductase
HWV68_17780	ENOG4105HUF	DNA protection during starvation protein
HWV68_17785	ENOG4105C0H	protease
HWV68_17795	ENOG4105F3H	Histidine kinase
HWV68_17805	ENOG41067SE	Tetr family transcriptional regulator
HWV68_17810	ENOG4105C9Q	fumarate hydratase class II
HWV68_17835	ENOG4105WH1	Two component transcriptional regulator luxr family
HWV68_17840	ENOG4105ENE	Histidine kinase
HWV68_17855	ENOG41087YS	Phage shock protein A
HWV68_17870	ENOG4108WBT	adenosyltransferase
HWV68_17875	ENOG4105E0A	ABC, transporter
HWV68_17880	ENOG4105EHG	Permease protein
HWV68_17885	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HWV68_17890	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HWV68_17895	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
HWV68_17905	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HWV68_17915	ENOG4106DF4	Sigma-70, region 4
HWV68_17925	ENOG4105F0F	Oxalate decarboxylase
HWV68_17935	ENOG4107RBB	ABC transporter, permease
HWV68_17940	ENOG4105C19	ABC transporter
HWV68_17945	ENOG4108WMK	Efflux transporter RND family MFP subunit
HWV68_17950	ENOG4105E0A	ABC, transporter
HWV68_17955	ENOG4105EHG	Permease protein
HWV68_17960	ENOG4105DQ5	transport system permease protein
HWV68_17970	ENOG4105D5Q	Arginine ornithine antiporter
HWV68_17980	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
HWV68_17985	ENOG4107QZ2	Sulfatase
HWV68_17990	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
HWV68_17995	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HWV68_18000	ENOG4105E0C	molybdate abc transporter
HWV68_18015	ENOG4105EEQ	Na H antiporter
HWV68_18020	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HWV68_18025	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HWV68_18030	ENOG4105EEM	helicase
HWV68_18035	ENOG4105EN6	Membrane
HWV68_18045	ENOG4107ZQN	disulfide bond
HWV68_18050	ENOG4105C59	p-type ATPase
HWV68_18055	ENOG4105C59	p-type ATPase
HWV68_18060	ENOG410681U	heavy metal transport detoxification protein
HWV68_18065	ENOG4105VPX	protein, conserved in bacteria
HWV68_18070	ENOG4105D9R	oxidoreductase
HWV68_18075	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HWV68_18080	ENOG4105ME7	Membrane
HWV68_18085	ENOG4105RXJ	
HWV68_18090	ENOG4105KPY	Small multidrug resistance protein
HWV68_18095	ENOG4105KBX	Transcriptional regulator, TetR family
HWV68_18100	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HWV68_18110	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HWV68_18115	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HWV68_18125	ENOG4105XZU	Preprotein translocase, subunit SecG
HWV68_18150	ENOG4105KVH	Transcriptional regulator
HWV68_18155	ENOG4105C8Q	Methyl-accepting chemotaxis
HWV68_18160	ENOG4105R40	Glycine betaine carnitine choline
HWV68_18165	ENOG4108HQR	Glycine betaine
HWV68_18170	ENOG4105E90	ABC transporter
HWV68_18175	ENOG4108IJ8	ABC transporter
HWV68_18180	ENOG4107HG4	Transcriptional regulator
HWV68_18190	ENOG4105H5S	
HWV68_18205	ENOG41082BM	Transcriptional regulator, arsr family
HWV68_18210	ENOG4105R40	Glycine betaine carnitine choline
HWV68_18215	ENOG4108HQR	Glycine betaine
HWV68_18220	ENOG4105E90	ABC transporter
HWV68_18225	ENOG4108IJ8	ABC transporter
HWV68_18230	ENOG4107HG4	Transcriptional regulator
HWV68_18235	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HWV68_18240	ENOG4108QCI	YvbH-like oligomerisation region
HWV68_18250	ENOG4105T65	Membrane-associated protein
HWV68_18255	ENOG4108W0I	acetyltransferase
HWV68_18260	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HWV68_18265	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HWV68_18270	ENOG4105CP7	Triose-phosphate isomerase
HWV68_18275	ENOG4105BZA	Phosphoglycerate kinase
HWV68_18280	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HWV68_18295	ENOG4105CMD	Transcriptional regulator, GntR family
HWV68_18300	ENOG4105DEN	Luciferase family
HWV68_18305	ENOG4105GZI	Transcriptional regulator
HWV68_18310	ENOG4107RT3	EamA-like transporter family
HWV68_18320	ENOG4105VRS	hydrolase family 18
HWV68_18325	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
HWV68_18330	ENOG4107QR9	Iron-sulfur cluster binding protein
HWV68_18335	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HWV68_18345	ENOG4105BZU	Histidine kinase
HWV68_18350	ENOG4105KCT	ABC transporter
HWV68_18355	ENOG4108M15	ABC transporter
HWV68_18360	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HWV68_18365	ENOG4108MJI	response regulator
HWV68_18380	ENOG4105EG2	ABC transporter, permease
HWV68_18390	ENOG4107FKK	extracellular solute-binding protein family 1
HWV68_18400	ENOG4105JXH	GntR family transcriptional regulator
HWV68_18405	ENOG4105DAA	L-lactate
HWV68_18410	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HWV68_18420	ENOG4108ZPC	Polysaccharide pyruvyl transferase
HWV68_18425	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HWV68_18430	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
HWV68_18435	ENOG4105D3Q	Sugar transferase
HWV68_18445	ENOG4105K64	Glycosyl transferase, family 2
HWV68_18455	ENOG4107QRS	glycosyltransferase group 2 family protein
HWV68_18460	ENOG41068W6	Capsular polysaccharide biosynthesis protein
HWV68_18465	ENOG4108KMV	Glycosyl transferase (Group 1
HWV68_18470	ENOG4105K64	Glycosyl transferase, family 2
HWV68_18475	ENOG4108PQP	glycosyl transferase group 1
HWV68_18485	ENOG4108QV3	biosynthesis protein
HWV68_18490	ENOG4105HTX	biosynthesis protein
HWV68_18500	ENOG4105EBR	Carboxylesterase
HWV68_18510	ENOG4105PY6	Phenolic acid decarboxylase
HWV68_18515	ENOG4105NI3	Protein of unknown function (DUF3237)
HWV68_18525	ENOG4105FQP	Beta-lactamase
HWV68_18530	ENOG4105EDQ	levansucrase EC 2.4.1.10
HWV68_18535	ENOG4108HKT	sucrose-6-phosphate hydrolase
HWV68_18540	ENOG4107QTZ	amino acid
HWV68_18565	ENOG4105DNP	FAD linked oxidase domain protein
HWV68_18570	ENOG4105IRW	patatin-like phospholipase family protein
HWV68_18580	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HWV68_18585	ENOG4107URF	beta-phospho-glucomutase
HWV68_18590	ENOG4105CG3	alpha amylase, catalytic region
HWV68_18605	ENOG4105EG2	ABC transporter, permease
HWV68_18610	ENOG4105D56	permease protein
HWV68_18615	ENOG4107FKK	extracellular solute-binding protein family 1
HWV68_18620	ENOG4108IUK	alpha amylase, catalytic
HWV68_18625	ENOG4105FKQ	transcriptional regulator
HWV68_18630	ENOG4108URH	decarboxylase
HWV68_18635	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
HWV68_18640	ENOG4105CHH	sulfate transporter
HWV68_18645	ENOG4108V2W	Carbonate dehydratase
HWV68_18650	ENOG4105C5I	Dehydrogenase
HWV68_18660	ENOG4105C19	ABC transporter
HWV68_18665	ENOG4105EWM	Histidine kinase
HWV68_18675	ENOG4107A6P	
HWV68_18680	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
HWV68_18685	ENOG4105KRI	phosphocarrier protein (HPr
HWV68_18690	ENOG4105CIE	May be required for sporulation (By similarity)
HWV68_18695	ENOG4105CHW	UPF0052 protein
HWV68_18700	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HWV68_18705	ENOG4108Z4K	mutator MutT protein
HWV68_18710	ENOG4105C3M	thioredoxin reductase
HWV68_18725	ENOG4105BZ1	(ABC) transporter
HWV68_18735	ENOG4106FGC	
HWV68_18745	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HWV68_18750	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HWV68_18755	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HWV68_18760	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HWV68_18765	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HWV68_18770	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HWV68_18775	ENOG4107RN8	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HWV68_18780	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HWV68_18790	ENOG4108E16	pectate lyase
HWV68_18795	ENOG4108S4C	acetyltransferase
HWV68_18800	ENOG4107XGZ	Hydrolase
HWV68_18805	ENOG4105HKU	nucleoside recognition domain-containing protein
HWV68_18810	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HWV68_18815	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HWV68_18820	ENOG4105CE4	GlcNAc 6-P deacetylase
HWV68_18825	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HWV68_18835	ENOG41088CQ	domain protein
HWV68_18845	ENOG4106A3M	Cytochrome p-450
HWV68_18850	ENOG410625E	
HWV68_18865	ENOG41086DT	Membrane protein of unknown function
HWV68_18870	ENOG41067S9	phage shock protein C, PspC
HWV68_18875	ENOG4108PY7	
HWV68_18895	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HWV68_18900	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HWV68_18915	ENOG4105MKU	Transcriptional regulator
HWV68_18935	ENOG4105CN1	protease
HWV68_18940	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HWV68_18945	ENOG4105CAK	Cell division ATP-binding protein ftsE
HWV68_18970	ENOG4105MS2	ribosomal subunit Interface protein
HWV68_18985	ENOG4105MQ3	flagellar protein FliS
HWV68_18990	ENOG4107RT6	flagellar hook-associated
HWV68_18995	ENOG41083S7	flagellar protein FlaG
HWV68_19000	ENOG4105I03	Flagellin
HWV68_19005	ENOG41085Y9	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HWV68_19010	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
HWV68_19015	ENOG4105MKD	
HWV68_19020	ENOG4105DTJ	flagellar hook-associated protein
HWV68_19025	ENOG4105E1Q	flagellar hook-associated protein
HWV68_19040	ENOG4105RU3	
HWV68_19045	ENOG41081UC	Inherit from COG: Competence protein
HWV68_19065	ENOG4105WH1	Two component transcriptional regulator luxr family
HWV68_19070	ENOG4105BZU	Histidine kinase
HWV68_19075	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HWV68_19080	ENOG4108KGH	TRANSCRIPTIONal
HWV68_19085	ENOG4105ESV	Glycosyl transferase, family 4
HWV68_19090	ENOG4107EF8	Glycosyl transferase (Group 1
HWV68_19105	ENOG4105QZI	O-Antigen Polymerase
HWV68_19110	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HWV68_19115	ENOG4107RA4	Glycosyl transferase (Group 1
HWV68_19120	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HWV68_19130	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HWV68_19135	ENOG4105JFG	SpoIID LytB domain protein
HWV68_19150	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HWV68_19155	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HWV68_19165	ENOG4107VDP	teichoic acid biosynthesis
HWV68_19170	ENOG41088M2	Glycosyl transferase family 2
HWV68_19180	ENOG4107SJB	teichoic acid biosynthesis
HWV68_19190	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HWV68_19195	ENOG4105EY8	ABC transporter
HWV68_19205	ENOG4107SJB	teichoic acid biosynthesis
HWV68_19210	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
HWV68_19215	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
HWV68_19225	ENOG4107RZX	Teichoic acid biosynthesis protein
HWV68_19230	ENOG410651K	Teichoic acid biosynthesis protein C
HWV68_19240	ENOG4105DG6	mannose-6-phosphate isomerase
HWV68_19255	ENOG4108NHD	germination protein
HWV68_19260	ENOG4105C54	Major Facilitator superfamily
HWV68_19265	ENOG4108KGH	TRANSCRIPTIONal
HWV68_19270	ENOG4105J7I	hydrolase
HWV68_19275	ENOG4105K4H	Nlp p60 protein
HWV68_19285	ENOG4105PNM	synthesis protein
HWV68_19295	ENOG4105N98	Capsule biosynthesis protein capB
HWV68_19300	ENOG4105ETE	Transcriptional regulator (LacI family
HWV68_19305	ENOG4108RVA	ribokinase
HWV68_19310	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HWV68_19315	ENOG4105C2J	ABC transporter
HWV68_19320	ENOG4105CNN	ABC, transporter
HWV68_19325	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HWV68_19340	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HWV68_19345	ENOG4107FQX	Alpha-acetolactate decarboxylase
HWV68_19355	ENOG4107RSM	transcriptional regulator
HWV68_19370	ENOG4106UIA	
HWV68_19385	ENOG4107XC4	flavin reductase domain protein, FMN-binding
HWV68_19395	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HWV68_19405	ENOG4105CAH	Chromate
HWV68_19410	ENOG4105FGV	Chromate
HWV68_19420	ENOG4108WS4	fmn reductase
HWV68_19425	ENOG4107V2S	Transcriptional regulator
HWV68_19430	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HWV68_19435	ENOG4106YAD	MORN repeat variant
HWV68_19460	ENOG4108XI2	Domain of unknown function (DUF1963)
HWV68_19465	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HWV68_19470	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
HWV68_19475	ENOG4107YJ4	chain length determinant protein
HWV68_19480	ENOG4105HTX	biosynthesis protein
HWV68_19490	ENOG4105KBK	Zinc finger, swim domain protein
HWV68_19495	ENOG4105C0D	helicase
HWV68_19500	ENOG410667J	hydrolase
HWV68_19505	ENOG4105E98	transcriptional regulator DeoR family
HWV68_19510	ENOG4105Z8H	single-stranded DNA-binding protein
HWV68_19540	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HWV68_19545	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HWV68_19555	ENOG4105CGA	flagellar basal-body rod protein FlgG
HWV68_19565	ENOG4105DFF	Rod shape-determining protein mreb
HWV68_19570	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
HWV68_19580	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
HWV68_19585	ENOG4105CZM	Major Facilitator
HWV68_19590	ENOG4108M26	parallel beta-helix repeat protein
HWV68_19595	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HWV68_19600	ENOG41080V3	Major Facilitator superfamily
HWV68_19605	ENOG4105D3W	isochorismatase
HWV68_19610	ENOG4107P26	
HWV68_19615	ENOG4105BZU	Histidine kinase
HWV68_19625	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HWV68_19635	ENOG4105FRN	stage II sporulation protein
HWV68_19640	ENOG4107TCE	N-acetyltransferase
HWV68_19660	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HWV68_19665	ENOG4107TXC	Transcriptional regulator
HWV68_19670	ENOG4106BRK	
HWV68_19675	ENOG4108RYK	Nad-dependent epimerase dehydratase
HWV68_19680	ENOG4108Z40	Transcriptional regulator
HWV68_19685	ENOG4105CQM	Urea amidohydrolase subunit alpha
HWV68_19690	ENOG4105KI2	Urea amidohydrolase subunit beta
HWV68_19695	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HWV68_19735	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HWV68_19745	ENOG4108TF4	von Willebrand factor, type A
HWV68_19760	ENOG4105JFG	SpoIID LytB domain protein
HWV68_19765	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HWV68_19775	ENOG4106778	Protein of unknown function (DUF1146)
HWV68_19785	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HWV68_19790	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HWV68_19795	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HWV68_19800	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HWV68_19820	ENOG4107RB6	it plays a direct role in the translocation of protons across the membrane (By similarity)
HWV68_19830	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HWV68_19835	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HWV68_19840	ENOG4108UIC	UPF0340 protein
HWV68_19845	ENOG4108YZG	isomerase
HWV68_19850	ENOG4107WAU	Protein tyrosine phosphatase
HWV68_19855	ENOG410815N	Probably functions as a manganese efflux pump (By similarity)
HWV68_19860	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HWV68_19870	ENOG4108ZXQ	stage ii sporulation protein r
HWV68_19885	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HWV68_19890	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HWV68_19895	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HWV68_19905	ENOG4107TT2	Auxin Efflux Carrier
HWV68_19910	ENOG4105C6K	Malic enzyme
HWV68_19915	ENOG4107104	thymidine kinase
HWV68_19925	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HWV68_19935	ENOG4105CBT	Fructose-1,6-bisphosphatase
HWV68_19940	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HWV68_19945	ENOG4107XMI	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HWV68_19950	ENOG4105D2N	Aldolase
HWV68_19955	ENOG410812K	response regulator receiver protein
HWV68_19965	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HWV68_19975	ENOG4105C1G	acyl-Coa dehydrogenase
HWV68_19980	ENOG4105DF6	Fe-S oxidoreductase
HWV68_19990	ENOG4105E5J	UV damage endonuclease
HWV68_20000	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HWV68_20005	ENOG4105BZ1	(ABC) transporter
HWV68_20010	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HWV68_20020	ENOG4105R3A	Nitrate reductase
HWV68_20025	ENOG4108IUE	nitrate reductase beta subunit
HWV68_20045	ENOG4107V6Q	Cyclic nucleotide-binding domain
HWV68_20055	ENOG4105C75	arginyL-tRNA synthetase
HWV68_20060	ENOG410684U	Domain of unknown function (DUF1934)
HWV68_20075	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
HWV68_20120	ENOG4107JM4	Tetratricopeptide repeat
HWV68_20130	ENOG4108UIN	ybak prolyl-trna synthetase associated region
HWV68_20135	ENOG4105CYW	agmatinase
HWV68_20140	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HWV68_20145	ENOG4105BZ4	penicillin-binding protein
HWV68_20150	ENOG4108XFG	YwhD family
HWV68_20155	ENOG4108Z4T	Peptidase M50
HWV68_20160	ENOG41069HH	4-oxalocrotonate tautomerase
HWV68_20165	ENOG41067TZ	transcriptional regulator, MarR family
HWV68_20170	ENOG4105C22	threonyL-tRNA synthetase
HWV68_20175	ENOG4105C57	major facilitator superfamily
HWV68_20180	ENOG41062ES	Transcriptional regulator
HWV68_20190	ENOG4105DCI	Phosphohydrolase
HWV68_20200	ENOG4108VCI	transcription factor, rsfa family
HWV68_20205	ENOG4108RNG	Permease of the drug metabolite transporter
HWV68_20210	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
HWV68_20215	ENOG4105DUM	transcriptional regulator, lysR family
HWV68_20220	ENOG4108IJ2	phosphate acetyltransferase
HWV68_20235	ENOG4105CHM	Aminotransferase
HWV68_20245	ENOG4108V3M	Inherit from COG: acetyl-CoA carboxylase biotin carboxylase
HWV68_20250	ENOG4105CHR	reductase
HWV68_20255	ENOG4106CHD	Bacilysin biosynthesis protein bacB
HWV68_20260	ENOG41061WN	bacilysin biosynthesis protein
HWV68_20265	ENOG4105FCW	Major Facilitator superfamily
HWV68_20280	ENOG4105C26	Dehydrogenase
HWV68_20285	ENOG4105D82	Glutamate dehydrogenase
HWV68_20295	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
HWV68_20300	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HWV68_20305	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HWV68_20310	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HWV68_20315	ENOG4107P9E	Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG
HWV68_20320	ENOG4107TY6	Acylneuraminate cytidylyltransferase
HWV68_20330	ENOG41067MN	Spore coat polysaccharide biosynthesis protein spsD
HWV68_20335	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HWV68_20370	ENOG4105C26	Dehydrogenase
HWV68_20375	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HWV68_20380	ENOG4108RJ9	Glycosyl transferase, family 2
HWV68_20400	ENOG4105DWF	phosphomethylpyrimidine kinase
HWV68_20415	ENOG4105C5Y	PTS System
HWV68_20420	ENOG4108QTI	)-transporter
HWV68_20435	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
HWV68_20440	ENOG4105DEN	Luciferase family
HWV68_20445	ENOG4108DBC	nitroreductase
HWV68_20460	ENOG41060D1	Quinol oxidase
HWV68_20465	ENOG4105CCU	oxidase (Subunit III)
HWV68_20470	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HWV68_20475	ENOG4105E2S	oxidase) subunit II
HWV68_20480	ENOG4107BMA	Transglycosylase associated protein
HWV68_20490	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HWV68_20495	ENOG4105WH5	Teichoic acid glycosylation protein
HWV68_20520	ENOG4107ZXU	DSBA oxidoreductase
HWV68_20525	ENOG4105DBE	peroxidase
HWV68_20530	ENOG410650H	(LipO)protein
HWV68_20535	ENOG4107SJW	iron permease, FTR1
HWV68_20540	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HWV68_20550	ENOG4105CMU	LysR family (Transcriptional regulator
HWV68_20555	ENOG4105VAW	lrga family
HWV68_20560	ENOG41067MG	lrgb family
HWV68_20565	ENOG4105D8G	Major Facilitator superfamily
HWV68_20575	ENOG4105DR4	Methyltransferase
HWV68_20585	ENOG4108YV3	Protein of unknown function (DUF2711)
HWV68_20590	ENOG4105CK1	PTS System
HWV68_20595	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
HWV68_20610	ENOG4105X1N	Glycosyl transferase family 8
HWV68_20620	ENOG4105GVJ	transcriptional regulator
HWV68_20625	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HWV68_20630	ENOG4105IIU	Aminopeptidase
HWV68_20640	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HWV68_20655	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
HWV68_20660	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HWV68_20670	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
HWV68_20675	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
HWV68_20680	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HWV68_20685	ENOG4105F8D	glycoside hydrolase family 4
HWV68_20690	ENOG4105VCP	PTS System
HWV68_20695	ENOG4105CK1	PTS System
HWV68_20700	ENOG4105VZJ	PTS System
HWV68_20705	ENOG4105EMD	TRANSCRIPTIONal
HWV68_20715	ENOG4108VX5	3-methyladenine DNA glycosylase
HWV68_20720	ENOG4105CH6	catalase
HWV68_20735	ENOG4105DA5	(ABC) transporter
HWV68_20740	ENOG41069JR	
HWV68_20760	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HWV68_20765	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HWV68_20770	ENOG4108JJ8	(ABC) transporter
HWV68_20775	ENOG4108JJ9	ABC, transporter
HWV68_20780	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HWV68_20785	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HWV68_20790	ENOG4105D2K	citrate carrier protein
HWV68_20805	ENOG4107BJW	polysaccharide deacetylase
HWV68_20825	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
HWV68_20835	ENOG4105CMR	udp-glucose 4-epimerase
HWV68_20840	ENOG4105KIS	phospholipid-binding protein
HWV68_20845	ENOG4108WAV	Transcriptional regulator
HWV68_20855	ENOG4105BZU	Histidine kinase
HWV68_20860	ENOG4105WH1	Two component transcriptional regulator luxr family
HWV68_20865	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HWV68_20890	ENOG4105DTD	Dehydrogenase
HWV68_20895	ENOG4108IIH	CoA-transferase subunit B
HWV68_20900	ENOG4105D6N	CoA-transferase, subunit a
HWV68_20905	ENOG4105CY2	Citrate transporter
HWV68_20910	ENOG4105DHI	Methyltransferase
HWV68_20930	ENOG4105CH6	catalase
HWV68_20935	ENOG4105D4T	Citrate transporter
HWV68_20940	ENOG4108RZ2	Glycoside hydrolase family 16
HWV68_20945	ENOG4105CID	antiterminator
HWV68_20955	ENOG4105DEU	major facilitator superfamily
HWV68_20960	ENOG4105C1J	atp-dependent rna helicase
HWV68_20965	ENOG4107TDE	lipolytic protein G-D-S-L family
HWV68_21020	ENOG4105CNA	YD repeat protein
HWV68_21030	ENOG4107YZX	Universal stress protein
HWV68_21035	ENOG4105CS2	ec 3.2.1.21
HWV68_21040	ENOG4105C5Y	PTS System
HWV68_21055	ENOG4107EV6	Inherit from COG: YD repeat protein
HWV68_21070	ENOG4106Z5D	Glycoside Hydrolase Family 43
HWV68_21085	ENOG4105C84	Histidine ammonia-lyase
HWV68_21090	ENOG4105CGP	Urocanate hydratase
HWV68_21095	ENOG4105CI2	imidazolone-5-propionate hydrolase
HWV68_21100	ENOG4107W25	arginase agmatinase formiminoglutamase
HWV68_21110	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HWV68_21115	ENOG4105D9N	nucleoside
HWV68_21125	ENOG4107RHR	regulatoR
HWV68_21130	ENOG4108TM9	integral membrane protein
HWV68_21135	ENOG4105ENY	Ethanolamine utilization protein eutH
HWV68_21140	ENOG4108PGP	mmge prpd family protein
HWV68_21155	ENOG4108HW4	amino acid AbC transporter
HWV68_21160	ENOG4105EAB	amino acid AbC transporter
HWV68_21180	ENOG4107QHE	Choloylglycine hydrolase
HWV68_21185	ENOG410667J	hydrolase
HWV68_21215	ENOG4108V5C	ABC transporter
HWV68_21245	ENOG4105D2N	Aldolase
HWV68_21250	ENOG4107TRN	Xylose isomerase domain protein TIM barrel
HWV68_21255	ENOG4105F0H	myo-inositol catabolism protein
HWV68_21260	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HWV68_21270	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
HWV68_21275	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
HWV68_21280	ENOG4105D7K	pfkb domain protein
HWV68_21285	ENOG4105DH8	myo-inositol catabolism
HWV68_21290	ENOG4105C26	Dehydrogenase
HWV68_21300	ENOG4105CPC	Aldo Keto reductase
HWV68_21315	ENOG4107QNK	)-transporter
HWV68_21320	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HWV68_21330	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HWV68_21335	ENOG4105ST3	Transcriptional regulator
HWV68_21340	ENOG4105C26	Dehydrogenase
HWV68_21345	ENOG4108YM7	Gcn5-related n-acetyltransferase
HWV68_21350	ENOG4105N1N	Cupin superfamily protein
HWV68_21355	ENOG4107Y1Y	Methyltransferase
HWV68_21370	ENOG4105CAQ	asparagine synthetase
HWV68_21375	ENOG4105F22	Major Facilitator Superfamily
HWV68_21380	ENOG4108ITS	PQQ enzyme repeat
HWV68_21390	ENOG41085PJ	rdd domain containing protein
HWV68_21405	ENOG4105J7D	transcriptional regulator
HWV68_21410	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
HWV68_21415	ENOG41061AU	MarR family Transcriptional regulator
HWV68_21425	ENOG41067MG	lrgb family
HWV68_21435	ENOG4105BZW	Glycerate kinase
HWV68_21440	ENOG4105G3Z	GntR family transcriptional regulator
HWV68_21445	ENOG4105CMG	Carbohydrate kinase
HWV68_21450	ENOG4105C6Z	Gluconate
HWV68_21455	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HWV68_21460	ENOG4105D3R	alkyl hydroperoxide reductase
HWV68_21465	ENOG4108JU3	Alkyl hydroperoxide reductase
HWV68_21470	ENOG4105CS2	ec 3.2.1.21
HWV68_21480	ENOG4108S3Y	transcriptional regulator
HWV68_21490	ENOG4106KKU	
HWV68_21495	ENOG4108Z15	abc transporter atp-binding protein
HWV68_21505	ENOG4105Y2Z	radical SAM domain protein
HWV68_21515	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HWV68_21530	ENOG41069I7	
HWV68_21535	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HWV68_21550	ENOG4105E2A	Dehydrogenase
HWV68_21570	ENOG4105NUN	Orthopoxvirus protein of unknown function (DUF830)
HWV68_21575	ENOG4105WQG	acetyltransferase
HWV68_21580	ENOG410780I	phosphoprotein phosphatase activity
HWV68_21590	ENOG41066UZ	arginase EC 3.5.3.1
HWV68_21595	ENOG4108IQI	permease
HWV68_21600	ENOG4105C8Y	Acetylornithine aminotransferase
HWV68_21605	ENOG4108JUB	Transcriptional regulator
HWV68_21620	ENOG4105C0H	protease
HWV68_21625	ENOG4105Q2H	domain protein
HWV68_21640	ENOG4105BZU	Histidine kinase
HWV68_21645	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HWV68_21670	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HWV68_21675	ENOG4105HB7	Glyoxalase Bleomycin resistance protein (Dioxygenase
HWV68_21680	ENOG4105CDU	Replicative dna helicase
HWV68_21700	ENOG4105DJ2	Major Facilitator Superfamily
HWV68_21705	ENOG4105EDW	glycosyl transferase, family 39
HWV68_21710	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HWV68_21715	ENOG4105BZR	domain protein
HWV68_21720	ENOG4108XMW	Membrane
HWV68_21735	ENOG4105KVH	Transcriptional regulator
HWV68_21740	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HWV68_21770	ENOG41060CM	Protein of unknown function (DUF2712)
HWV68_21775	ENOG4106NWU	
HWV68_21780	ENOG41064J9	
HWV68_21785	ENOG41064SH	Protein of unknown function (DUF2705)
HWV68_21790	ENOG4108RDQ	ABC transporter
HWV68_21805	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
HWV68_21810	ENOG4105DDN	Pentapeptide repeat-containing protein
HWV68_21815	ENOG4105D94	Major Facilitator Superfamily
HWV68_21820	ENOG4107RSM	transcriptional regulator
HWV68_21825	ENOG41082BV	acetyltransferase
HWV68_21830	ENOG41081I9	integral membrane protein
HWV68_21840	ENOG4108U05	Transcriptional regulator
HWV68_21845	ENOG41082BV	acetyltransferase
HWV68_21855	ENOG4108U7W	acetyltransferase
HWV68_21860	ENOG4105UNS	Pfam:DUF419
HWV68_21865	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HWV68_21875	ENOG4108J8C	transporter major facilitator family protein
HWV68_21895	ENOG4108IPJ	Membrane
HWV68_21900	ENOG4105C7Z	Conserved Protein
HWV68_21905	ENOG4107FCW	Abortive infection protein
HWV68_21915	ENOG4108UW5	maltose o-acetyltransferase
HWV68_21920	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
HWV68_21930	ENOG4105CGK	Exodeoxyribonuclease III
HWV68_21935	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HWV68_21940	ENOG4108UUM	single-stranded DNA-binding protein
HWV68_21945	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HWV68_21950	ENOG4105C3G	gtp-binding protein
HWV68_21955	ENOG4108J2R	molybdopterin oxidoreductase
HWV68_21960	ENOG4105VDK	protein, conserved in bacteria
HWV68_21970	ENOG4108ZDA	Sporulation protein YyaC
HWV68_21975	ENOG4105FA0	parb-like partition protein
HWV68_21980	ENOG4107QJE	Chromosome Partitioning Protein
HWV68_21995	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HWV68_22000	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HWV68_22005	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HWV68_22020	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)