locus-tag	class	description
C7M23_00001	COG2211	Major facilitator Superfamily
C7M23_00002	COG1063	alcohol dehydrogenase
C7M23_00003	COG0457	Tetratricopeptide repeat
C7M23_00004	COG1073	alpha beta
C7M23_00005	COG0459	protein refolding
C7M23_00007	COG1266	CAAX protease self-immunity
C7M23_00009	COG0805	protein transport
C7M23_00010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M23_00011	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7M23_00012	COG0315	cyclic pyranopterin monophosphate synthase activity
C7M23_00013	COG0488	(ABC) transporter
C7M23_00014	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M23_00015	COG0456	acetyltransferase
C7M23_00016	COG1214	PFAM Peptidase M22, glycoprotease
C7M23_00017	COG0802	atpase or kinase
C7M23_00018	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7M23_00027	COG4124	Belongs to the glycosyl hydrolase 26 family
C7M23_00028	COG1482	cell wall glycoprotein biosynthetic process
C7M23_00029	COG1940	carbohydrate kinase activity
C7M23_00030	COG2188	Transcriptional regulator
C7M23_00031	COG2723	6-phospho-beta-galactosidase activity
C7M23_00032	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M23_00033	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M23_00034	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M23_00035	COG2814	Major facilitator Superfamily
C7M23_00036	COG1388	LysM domain
C7M23_00037	COG1078	dGTPase activity
C7M23_00038	COG0454	-acetyltransferase
C7M23_00040	COG5646	InterPro IPR014922
C7M23_00041	COG1785	Belongs to the alkaline phosphatase family
C7M23_00043	COG1819	glycosyl
C7M23_00044	COG3858	chitin binding
C7M23_00044	COG1388	LysM domain
C7M23_00045	COG1802	Transcriptional regulator
C7M23_00046	COG0730	response to heat
C7M23_00047	COG2814	Major facilitator Superfamily
C7M23_00048	COG1846	Transcriptional regulator
C7M23_00049	COG0778	Nitroreductase
C7M23_00050	COG2409	Drug exporters of the RND superfamily
C7M23_00050	COG1033	growth of symbiont in host cell
C7M23_00051	COG1846	Transcriptional regulator
C7M23_00052	COG2318	DinB family
C7M23_00053	COG1113	amino acid transport
C7M23_00055	COG0456	acetyltransferase
C7M23_00057	COG1309	transcriptional regulator
C7M23_00060	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M23_00061	COG2323	membrane
C7M23_00062	COG2323	membrane
C7M23_00066	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M23_00067	COG2259	Doxx family
C7M23_00068	COG0346	lactoylglutathione lyase activity
C7M23_00069	COG0778	Nitroreductase
C7M23_00070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M23_00071	COG0789	Transcriptional regulator
C7M23_00071	COG4978	Transcriptional regulator
C7M23_00072	COG1811	Na channel or pump
C7M23_00073	COG0596	Alpha beta hydrolase
C7M23_00074	COG2409	Drug exporters of the RND superfamily
C7M23_00075	COG2197	response regulator
C7M23_00076	COG4585	Histidine kinase
C7M23_00078	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M23_00079	COG0640	Transcriptional regulator
C7M23_00080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M23_00081	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M23_00082	COG0697	spore germination
C7M23_00083	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M23_00084	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M23_00085	COG0640	Transcriptional regulator
C7M23_00086	COG1309	transcriptional regulator
C7M23_00087	COG2814	Major facilitator Superfamily
C7M23_00088	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M23_00089	COG1733	regulation of RNA biosynthetic process
C7M23_00090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M23_00091	COG1733	regulation of RNA biosynthetic process
C7M23_00092	COG3545	Serine hydrolase
C7M23_00093	COG2030	dehydratase
C7M23_00094	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M23_00095	COG0697	spore germination
C7M23_00096	COG1309	transcriptional regulator
C7M23_00100	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C7M23_00101	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C7M23_00103	COG0477	Major facilitator Superfamily
C7M23_00104	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M23_00105	COG3708	Transcriptional regulator
C7M23_00105	COG2207	Transcriptional regulator
C7M23_00106	COG0697	spore germination
C7M23_00107	COG2207	Transcriptional regulator
C7M23_00107	COG1917	Cupin 2, conserved barrel domain protein
C7M23_00108	COG0697	spore germination
C7M23_00109	COG1329	Transcriptional regulator
C7M23_00110	COG1278	Cold shock
C7M23_00111	COG0693	protein deglycase activity
C7M23_00116	COG1476	TRANSCRIPTIONal
C7M23_00119	COG5444	nuclease activity
C7M23_00123	COG0457	Tetratricopeptide repeat
C7M23_00124	COG0210	DNA helicase
C7M23_00128	COG0741	lytic transglycosylase activity
C7M23_00128	COG0791	NLP P60 protein
C7M23_00129	COG5644	endopeptidase inhibitor activity
C7M23_00131	COG0433	COG0433 Predicted ATPase
C7M23_00139	COG2946	Replication initiation factor
C7M23_00140	COG1674	ftsk spoiiie
C7M23_00146	COG1396	sequence-specific DNA binding
C7M23_00147	COG2856	Zn peptidase
C7M23_00148	COG0582	viral genome integration into host DNA
C7M23_00156	COG3091	SprT-like family
C7M23_00157	COG2183	response to ionizing radiation
C7M23_00158	COG2208	phosphoserine phosphatase activity
C7M23_00159	COG1191	sigma factor activity
C7M23_00160	COG2172	sigma factor antagonist activity
C7M23_00161	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M23_00162	COG2208	phosphoserine phosphatase activity
C7M23_00163	COG2172	sigma factor antagonist activity
C7M23_00164	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M23_00165	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M23_00166	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M23_00167	COG0864	Transcriptional regulator
C7M23_00168	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M23_00169	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7M23_00170	COG0736	holo-[acyl-carrier-protein] synthase activity
C7M23_00171	COG0705	Rhomboid family
C7M23_00172	COG3428	Bacterial PH domain
C7M23_00173	COG3402	PFAM membrane-flanked domain
C7M23_00174	COG0513	Belongs to the DEAD box helicase family
C7M23_00175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M23_00176	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M23_00177	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M23_00178	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M23_00181	COG1960	acyl-CoA dehydrogenase activity
C7M23_00183	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M23_00184	COG1131	(ABC) transporter
C7M23_00185	COG0628	permease
C7M23_00186	COG1301	dicarboxylic acid transport
C7M23_00187	COG4565	transcriptional regulatory protein
C7M23_00188	COG3290	protein histidine kinase activity
C7M23_00189	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7M23_00190	COG3546	catalase activity
C7M23_00191	COG2329	Antibiotic biosynthesis monooxygenase
C7M23_00192	COG0662	Cupin 2, conserved barrel domain protein
C7M23_00193	COG3729	General stress protein
C7M23_00194	COG2217	Heavy metal translocating P-type atpase
C7M23_00195	COG4876	unkown
C7M23_00196	COG2261	transglycosylase associated protein
C7M23_00197	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M23_00199	COG0028	Belongs to the TPP enzyme family
C7M23_00200	COG0494	nUDIX hydrolase
C7M23_00201	COG0531	amino acid
C7M23_00203	COG1215	transferase activity, transferring glycosyl groups
C7M23_00204	COG5298	Protein conserved in bacteria
C7M23_00205	COG3706	GGDEF domain
C7M23_00206	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C7M23_00207	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M23_00207	COG0551	DNA topoisomerase type I activity
C7M23_00208	COG1522	sequence-specific DNA binding
C7M23_00209	COG2814	Major facilitator Superfamily
C7M23_00211	COG3871	stress protein (general stress protein 26)
C7M23_00212	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M23_00213	COG1917	Cupin 2, conserved barrel domain protein
C7M23_00214	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_00215	COG2226	methyltransferase
C7M23_00216	COG0318	PFAM AMP-dependent synthetase and ligase
C7M23_00217	COG3711	transcriptional antiterminator
C7M23_00218	COG4989	oxidoreductase activity
C7M23_00219	COG0768	penicillin binding
C7M23_00220	COG2329	Antibiotic biosynthesis monooxygenase
C7M23_00222	COG2755	lipolytic protein G-D-S-L family
C7M23_00223	COG1414	Transcriptional regulator
C7M23_00224	COG1984	allophanate hydrolase subunit 2
C7M23_00225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7M23_00226	COG4336	lyase activity
C7M23_00227	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M23_00228	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C7M23_00229	COG0561	phosphatase activity
C7M23_00231	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M23_00232	COG0412	Dienelactone hydrolase
C7M23_00233	COG0681	Belongs to the peptidase S26 family
C7M23_00234	COG0473	3-isopropylmalate dehydrogenase activity
C7M23_00235	COG0246	Mannitol dehydrogenase
C7M23_00236	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M23_00237	COG2213	PTS system mannitol-specific
C7M23_00239	COG1349	DNA-binding transcription factor activity
C7M23_00240	COG1276	copper resistance
C7M23_00240	COG2372	response to copper ion
C7M23_00241	COG4549	nuclear export factor GLE1
C7M23_00242	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_00243	COG4975	Glucose uptake
C7M23_00244	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_00245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M23_00246	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M23_00247	COG0640	Transcriptional regulator
C7M23_00248	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M23_00249	COG0778	Nitroreductase
C7M23_00250	COG1309	transcriptional regulator
C7M23_00251	COG2814	Major facilitator Superfamily
C7M23_00252	COG4607	ABC-type enterochelin transport system periplasmic component
C7M23_00253	COG4604	ABC transporter, ATP-binding protein
C7M23_00254	COG4605	iron ion homeostasis
C7M23_00255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M23_00256	COG0527	aspartate kinase activity
C7M23_00260	COG0457	Tetratricopeptide repeat
C7M23_00261	COG3850	Histidine kinase
C7M23_00261	COG5002	protein histidine kinase activity
C7M23_00262	COG0745	RESPONSE REGULATOR receiver
C7M23_00263	COG0577	efflux transmembrane transporter activity
C7M23_00264	COG1136	(ABC) transporter
C7M23_00265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M23_00267	COG0697	spore germination
C7M23_00269	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M23_00270	COG3104	oligopeptide transport
C7M23_00271	COG0596	Alpha beta hydrolase
C7M23_00274	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M23_00275	COG0163	prenyltransferase activity
C7M23_00276	COG0583	DNA-binding transcription factor activity
C7M23_00277	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M23_00278	COG0765	amino acid transport
C7M23_00279	COG1126	abc transporter atp-binding protein
C7M23_00280	COG2364	Membrane
C7M23_00282	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M23_00283	COG0697	spore germination
C7M23_00285	COG2814	Major facilitator Superfamily
C7M23_00286	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7M23_00287	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_00288	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_00289	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_00290	COG1733	regulation of RNA biosynthetic process
C7M23_00291	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7M23_00292	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M23_00293	COG0840	transmembrane signaling receptor activity
C7M23_00293	COG3290	protein histidine kinase activity
C7M23_00294	COG3209	COG3209 Rhs family protein
C7M23_00296	COG2723	6-phospho-beta-galactosidase activity
C7M23_00298	COG1714	RDD family
C7M23_00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M23_00301	COG0765	amino acid transport
C7M23_00302	COG0523	cobalamin synthesis protein
C7M23_00303	COG1376	ErfK ybiS ycfS ynhG family protein
C7M23_00304	COG1469	GTP cyclohydrolase I activity
C7M23_00305	COG2223	nitrite transmembrane transporter activity
C7M23_00306	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M23_00307	COG0243	molybdopterin cofactor binding
C7M23_00308	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M23_00309	COG2146	nitrite reductase [NAD(P)H] activity
C7M23_00310	COG1587	Uroporphyrinogen-III synthase
C7M23_00310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M23_00311	COG0492	ferredoxin-NADP+ reductase activity
C7M23_00312	COG2267	carboxylic ester hydrolase activity
C7M23_00313	COG0701	Predicted permease
C7M23_00314	COG3689	TIGRFAM TIGR03943 family protein
C7M23_00315	COG2508	Transcriptional regulator
C7M23_00316	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M23_00317	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_00318	COG0506	proline dehydrogenase activity
C7M23_00319	COG3541	Predicted nucleotidyltransferase
C7M23_00320	COG3458	cephalosporin-C deacetylase activity
C7M23_00321	COG0583	DNA-binding transcription factor activity
C7M23_00322	COG2226	methyltransferase
C7M23_00323	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M23_00324	COG1660	Displays ATPase and GTPase activities
C7M23_00325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7M23_00326	COG3665	Urea carboxylase-associated protein
C7M23_00327	COG1113	amino acid transport
C7M23_00328	COG3403	YqcI/YcgG family
C7M23_00329	COG1280	lysine exporter protein (LysE YggA)
C7M23_00330	COG1846	Transcriptional regulator
C7M23_00331	COG2814	Major facilitator Superfamily
C7M23_00332	COG1620	l-lactate permease
C7M23_00333	COG0039	L-malate dehydrogenase activity
C7M23_00334	COG0366	Alpha amylase catalytic
C7M23_00336	COG1288	antiporter activity
C7M23_00337	COG1473	amidohydrolase
C7M23_00338	COG2113	Glycine betaine
C7M23_00339	COG4176	ABC-type proline glycine betaine transport system permease component
C7M23_00340	COG0517	IMP dehydrogenase activity
C7M23_00340	COG4175	Glycine betaine
C7M23_00341	COG0640	Transcriptional regulator
C7M23_00342	COG2814	Major facilitator Superfamily
C7M23_00343	COG0477	Major facilitator Superfamily
C7M23_00344	COG3853	Toxic anion resistance protein (TelA)
C7M23_00346	COG0861	Integral membrane protein TerC family
C7M23_00347	COG2310	stress, protein
C7M23_00348	COG2310	stress, protein
C7M23_00349	COG2310	stress, protein
C7M23_00350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M23_00351	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M23_00352	COG1121	(ABC) transporter
C7M23_00353	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M23_00354	COG0366	Alpha amylase catalytic
C7M23_00355	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_00356	COG0457	Tetratricopeptide repeat
C7M23_00357	COG1876	peptidase activity
C7M23_00358	COG1595	DNA-templated transcription, initiation
C7M23_00359	COG1595	DNA-templated transcription, initiation
C7M23_00361	COG0667	Aldo Keto reductase
C7M23_00362	COG1668	transmembrane transport
C7M23_00363	COG4555	ABC transporter
C7M23_00364	COG3279	Response regulator of the LytR AlgR family
C7M23_00365	COG3290	protein histidine kinase activity
C7M23_00366	COG1405	negative regulation of cell septum assembly
C7M23_00366	COG3012	SEC-C Motif Domain Protein
C7M23_00367	COG1714	RDD family
C7M23_00368	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M23_00369	COG0252	asparaginase activity
C7M23_00370	COG1309	transcriptional regulator
C7M23_00371	COG0477	Major facilitator Superfamily
C7M23_00372	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M23_00373	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7M23_00374	COG0805	protein transport
C7M23_00375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M23_00376	COG3540	Alkaline phosphatase
C7M23_00377	COG2304	oxidoreductase activity
C7M23_00378	COG3773	Cell wall hydrolase
C7M23_00381	COG1131	(ABC) transporter
C7M23_00382	COG2205	protein histidine kinase activity
C7M23_00383	COG0745	RESPONSE REGULATOR receiver
C7M23_00384	COG0697	spore germination
C7M23_00386	COG3173	Aminoglycoside phosphotransferase
C7M23_00387	COG2721	sulfolactate sulfo-lyase activity
C7M23_00388	COG2186	Transcriptional regulator
C7M23_00389	COG4948	Mandelate Racemase Muconate Lactonizing
C7M23_00390	COG2271	Major facilitator Superfamily
C7M23_00391	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_00392	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M23_00393	COG0784	Response regulator, receiver
C7M23_00394	COG4191	Histidine kinase
C7M23_00395	COG2066	Belongs to the glutaminase family
C7M23_00396	COG1115	amino acid carrier protein
C7M23_00397	COG2040	homocysteine
C7M23_00398	COG0833	amino acid
C7M23_00399	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M23_00401	COG2188	Transcriptional regulator
C7M23_00402	COG0363	glucosamine-6-phosphate deaminase activity
C7M23_00403	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M23_00403	COG2190	(PTS) system
C7M23_00403	COG1263	PTS System
C7M23_00404	COG1301	dicarboxylic acid transport
C7M23_00406	COG2207	Transcriptional regulator
C7M23_00407	COG2312	Erythromycin esterase
C7M23_00409	COG0688	phosphatidylethanolamine metabolic process
C7M23_00410	COG0586	Pfam SNARE associated Golgi protein
C7M23_00411	COG1183	phosphatidylcholine synthase activity
C7M23_00412	COG0596	Alpha beta hydrolase
C7M23_00414	COG3591	Belongs to the peptidase S1B family
C7M23_00415	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7M23_00416	COG1917	Cupin 2, conserved barrel domain protein
C7M23_00416	COG2207	Transcriptional regulator
C7M23_00417	COG0697	spore germination
C7M23_00418	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_00420	COG2271	Major facilitator Superfamily
C7M23_00421	COG0456	acetyltransferase
C7M23_00421	COG1846	Transcriptional regulator
C7M23_00423	COG2271	Major facilitator Superfamily
C7M23_00424	COG0584	glycerophosphoryl diester phosphodiesterase
C7M23_00425	COG0531	amino acid
C7M23_00427	COG2124	cytochrome p450
C7M23_00428	COG2602	Beta-lactamase
C7M23_00429	COG2602	Beta-lactamase
C7M23_00432	COG1113	amino acid transport
C7M23_00435	COG0515	serine threonine protein kinase
C7M23_00437	COG0642	Histidine kinase
C7M23_00438	COG0745	RESPONSE REGULATOR receiver
C7M23_00439	COG0596	Alpha beta hydrolase
C7M23_00440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M23_00441	COG1413	lyase activity
C7M23_00443	COG1131	(ABC) transporter
C7M23_00444	COG1266	CAAX protease self-immunity
C7M23_00445	COG0535	radical SAM domain protein
C7M23_00447	COG2814	Major facilitator Superfamily
C7M23_00448	COG0640	Transcriptional regulator
C7M23_00450	COG5609	conserved protein (DUF2294)
C7M23_00452	COG0288	reversible hydration of carbon dioxide
C7M23_00453	COG3002	Belongs to the UPF0753 family
C7M23_00454	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M23_00455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M23_00456	COG2169	Transcriptional regulator
C7M23_00457	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M23_00458	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M23_00459	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M23_00460	COG4856	YbbR-like protein
C7M23_00461	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M23_00462	COG5662	AntiSigma factor
C7M23_00463	COG1595	DNA-templated transcription, initiation
C7M23_00469	COG1683	Conserved Protein
C7M23_00470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M23_00471	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M23_00472	COG1737	Transcriptional regulator
C7M23_00473	COG1263	PTS System
C7M23_00473	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M23_00474	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M23_00475	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M23_00476	COG3876	Protein conserved in bacteria
C7M23_00477	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M23_00477	COG2207	Transcriptional regulator
C7M23_00478	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M23_00479	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M23_00480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M23_00481	COG2819	hydrolase of the alpha beta superfamily
C7M23_00482	COG0385	Bile acid
C7M23_00484	COG0659	secondary active sulfate transmembrane transporter activity
C7M23_00501	COG0726	polysaccharide deacetylase
C7M23_00502	COG2194	sulfuric ester hydrolase activity
C7M23_00504	COG0489	protein tyrosine kinase activity
C7M23_00505	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M23_00507	COG2226	methyltransferase
C7M23_00508	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7M23_00509	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7M23_00510	COG0101	tRNA pseudouridine synthase activity
C7M23_00511	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M23_00512	COG1122	ATPase activity
C7M23_00513	COG1122	ATPase activity
C7M23_00514	COG0203	ribosomal protein L17
C7M23_00515	COG0202	RNA polymerase activity
C7M23_00516	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7M23_00517	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7M23_00518	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M23_00520	COG0024	Methionine aminopeptidase
C7M23_00521	COG0563	adenylate kinase activity
C7M23_00522	COG0201	protein transport
C7M23_00523	COG0200	Binds to the 23S rRNA
C7M23_00526	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7M23_00527	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7M23_00528	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7M23_00530	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7M23_00532	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7M23_00533	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7M23_00535	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M23_00536	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7M23_00539	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7M23_00541	COG0088	Forms part of the polypeptide exit tunnel
C7M23_00542	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7M23_00544	COG0596	Alpha beta hydrolase
C7M23_00545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7M23_00546	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7M23_00547	COG0049	tRNA binding
C7M23_00548	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7M23_00549	COG1358	cellular component organization or biogenesis
C7M23_00550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7M23_00551	COG0085	RNA polymerase activity
C7M23_00552	COG2813	Specifically methylates the guanine in position
C7M23_00554	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7M23_00555	COG0081	regulation of translation
C7M23_00557	COG0250	Participates in transcription elongation, termination and antitermination
C7M23_00558	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M23_00559	COG1595	DNA-templated transcription, initiation
C7M23_00560	COG3688	RNA-binding protein containing a PIN domain
C7M23_00561	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M23_00562	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M23_00563	COG0215	cysteine-tRNA ligase activity
C7M23_00564	COG1045	serine acetyltransferase
C7M23_00565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7M23_00566	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7M23_00567	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7M23_00568	COG4956	integral membrane protein (PIN domain superfamily)
C7M23_00569	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C7M23_00570	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7M23_00571	COG0542	response to heat
C7M23_00572	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C7M23_00573	COG3880	PFAM UvrB UvrC protein
C7M23_00574	COG4463	regulation of RNA biosynthetic process
C7M23_00590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M23_00591	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M23_00592	COG1396	sequence-specific DNA binding
C7M23_00593	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M23_00594	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7M23_00595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7M23_00596	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M23_00597	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M23_00598	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M23_00599	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M23_00600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M23_00601	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7M23_00602	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C7M23_00603	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M23_00605	COG0037	tRNA processing
C7M23_00606	COG0515	serine threonine protein kinase
C7M23_00607	COG2304	oxidoreductase activity
C7M23_00608	COG2208	phosphoserine phosphatase activity
C7M23_00611	COG1098	S1 RNA binding domain
C7M23_00612	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7M23_00615	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M23_00616	COG3956	TIGRFAM MazG family protein
C7M23_00617	COG2244	polysaccharide biosynthetic process
C7M23_00618	COG2002	toxin-antitoxin pair type II binding
C7M23_00619	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M23_00621	COG0193	aminoacyl-tRNA hydrolase activity
C7M23_00622	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7M23_00623	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M23_00624	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7M23_00625	COG2088	sporulation resulting in formation of a cellular spore
C7M23_00626	COG0251	oxidation-reduction process
C7M23_00627	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M23_00628	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7M23_00629	COG4466	Protein conserved in bacteria
C7M23_00631	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M23_00632	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M23_00633	COG3583	domain protein
C7M23_00633	COG3584	3D domain protein
C7M23_00634	COG0084	hydrolase, TatD family'
C7M23_00635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M23_00635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M23_00636	COG2002	toxin-antitoxin pair type II binding
C7M23_00637	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7M23_00638	COG2827	Endonuclease containing a URI domain
C7M23_00639	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M23_00640	COG4467	Involved in initiation control of chromosome replication
C7M23_00641	COG1774	PSP1 C-terminal conserved region
C7M23_00642	COG0470	DNA polymerase III
C7M23_00643	COG1728	Protein conserved in bacteria
C7M23_00644	COG3870	Protein conserved in bacteria
C7M23_00645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M23_00646	COG1982	Orn Lys Arg decarboxylase major
C7M23_00647	COG3853	Toxic anion resistance protein (TelA)
C7M23_00648	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C7M23_00657	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7M23_00658	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M23_00659	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M23_00660	COG0590	tRNA wobble adenosine to inosine editing
C7M23_00661	COG1335	isochorismatase
C7M23_00662	COG1388	LysM domain
C7M23_00662	COG3858	chitin binding
C7M23_00663	COG1428	Deoxynucleoside kinase
C7M23_00664	COG1428	Deoxynucleoside kinase
C7M23_00666	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M23_00667	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C7M23_00668	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C7M23_00669	COG1686	Belongs to the peptidase S11 family
C7M23_00670	COG0517	IMP dehydrogenase activity
C7M23_00670	COG0516	GMP reductase activity
C7M23_00677	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M23_00678	COG0187	DNA topoisomerase II activity
C7M23_00680	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7M23_00681	COG2501	S4 domain
C7M23_00682	COG0592	DNA-directed DNA polymerase activity
C7M23_00683	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7M23_00684	COG0594	ribonuclease P activity
C7M23_00685	COG0706	membrane insertase activity
C7M23_00686	COG1847	R3H domain protein
C7M23_00687	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7M23_00688	COG0445	tRNA wobble uridine modification
C7M23_00689	COG0357	Ribosomal RNA small subunit methyltransferase G
C7M23_00690	COG1475	DNA binding
C7M23_00692	COG1192	Involved in chromosome partitioning
C7M23_00693	COG1475	DNA binding
C7M23_00695	COG3949	Membrane
C7M23_00696	COG4481	Protein conserved in bacteria
C7M23_00697	COG0243	molybdopterin cofactor binding
C7M23_00698	COG0012	GTP binding
C7M23_00699	COG0360	Binds together with S18 to 16S ribosomal RNA
C7M23_00700	COG0629	single-stranded DNA binding
C7M23_00701	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7M23_00702	COG0708	Exodeoxyribonuclease III
C7M23_00703	COG1609	Transcriptional regulator
C7M23_00704	COG0346	lactoylglutathione lyase activity
C7M23_00705	COG0110	maltose O-acetyltransferase activity
C7M23_00706	COG2814	Major facilitator Superfamily
C7M23_00706	COG0477	Major facilitator Superfamily
C7M23_00707	COG1266	CAAX protease self-immunity
C7M23_00708	COG1331	Highly conserved protein containing a thioredoxin domain
C7M23_00710	COG0640	Transcriptional regulator
C7M23_00711	COG0346	lactoylglutathione lyase activity
C7M23_00712	COG0798	PFAM Bile acid sodium symporter
C7M23_00713	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M23_00715	COG1733	regulation of RNA biosynthetic process
C7M23_00716	COG1331	Highly conserved protein containing a thioredoxin domain
C7M23_00717	COG2814	Major facilitator Superfamily
C7M23_00718	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M23_00719	COG2315	Protein conserved in bacteria
C7M23_00720	COG0456	acetyltransferase
C7M23_00721	COG2364	Membrane
C7M23_00722	COG2153	protein acetylation
C7M23_00723	COG1846	Transcriptional regulator
C7M23_00724	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M23_00726	COG2153	protein acetylation
C7M23_00727	COG0583	DNA-binding transcription factor activity
C7M23_00728	COG2814	Major facilitator Superfamily
C7M23_00729	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M23_00730	COG4319	ketosteroid isomerase
C7M23_00732	COG0789	Transcriptional regulator
C7M23_00732	COG4978	Transcriptional regulator
C7M23_00733	COG2271	Major facilitator Superfamily
C7M23_00736	COG1227	inorganic diphosphatase activity
C7M23_00737	COG1733	regulation of RNA biosynthetic process
C7M23_00738	COG5577	PFAM Coat F domain
C7M23_00740	COG4241	membrane
C7M23_00741	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7M23_00742	COG0359	binds to the 23S rRNA
C7M23_00743	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M23_00744	COG2807	transmembrane transport
C7M23_00745	COG3093	addiction module antidote protein HigA
C7M23_00748	COG0305	Participates in initiation and elongation during chromosome replication
C7M23_00749	COG0346	lactoylglutathione lyase activity
C7M23_00755	COG0745	RESPONSE REGULATOR receiver
C7M23_00756	COG5002	protein histidine kinase activity
C7M23_00757	COG4863	YycH protein
C7M23_00758	COG4853	Protein conserved in bacteria
C7M23_00759	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M23_00760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M23_00764	COG5002	protein histidine kinase activity
C7M23_00765	COG3829	transcription factor binding
C7M23_00766	COG0640	Transcriptional regulator
C7M23_00767	COG5658	integral membrane protein
C7M23_00771	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M23_00772	COG0833	amino acid
C7M23_00773	COG0010	Belongs to the arginase family
C7M23_00775	COG0457	Tetratricopeptide repeat
C7M23_00776	COG0456	acetyltransferase
C7M23_00777	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C7M23_00781	COG1063	alcohol dehydrogenase
C7M23_00784	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7M23_00785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M23_00787	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C7M23_00788	COG1131	(ABC) transporter
C7M23_00791	COG2188	Transcriptional regulator
C7M23_00792	COG2190	(PTS) system
C7M23_00793	COG2723	6-phospho-beta-galactosidase activity
C7M23_00795	COG3634	alkyl hydroperoxide reductase activity
C7M23_00796	COG0450	alkyl hydroperoxide reductase
C7M23_00797	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M23_00798	COG2610	gluconate transmembrane transporter activity
C7M23_00799	COG1070	Carbohydrate kinase
C7M23_00800	COG1802	Transcriptional regulator
C7M23_00801	COG1929	Belongs to the glycerate kinase type-1 family
C7M23_00802	COG5039	Polysaccharide pyruvyl transferase
C7M23_00803	COG1346	cytolysis
C7M23_00804	COG1380	Effector of murein hydrolase LrgA
C7M23_00805	COG1846	Transcriptional regulator
C7M23_00806	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_00807	COG1309	transcriptional regulator
C7M23_00808	COG1917	Cupin 2, conserved barrel domain protein
C7M23_00809	COG2311	Membrane
C7M23_00810	COG1714	RDD family
C7M23_00812	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7M23_00813	COG1714	RDD family
C7M23_00815	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_00816	COG1309	transcriptional regulator
C7M23_00817	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_00819	COG0326	Molecular chaperone. Has ATPase activity
C7M23_00820	COG2814	Major facilitator Superfamily
C7M23_00823	COG0667	Aldo Keto reductase
C7M23_00824	COG1349	DNA-binding transcription factor activity
C7M23_00825	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_00827	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M23_00828	COG3962	Belongs to the TPP enzyme family
C7M23_00829	COG1082	Xylose isomerase domain protein TIM barrel
C7M23_00830	COG2814	Major facilitator Superfamily
C7M23_00831	COG0673	inositol 2-dehydrogenase activity
C7M23_00832	COG1082	Xylose isomerase domain protein TIM barrel
C7M23_00833	COG1082	Xylose isomerase domain protein TIM barrel
C7M23_00834	COG0191	fructose-bisphosphate aldolase activity
C7M23_00835	COG0745	RESPONSE REGULATOR receiver
C7M23_00836	COG2205	protein histidine kinase activity
C7M23_00837	COG1136	(ABC) transporter
C7M23_00838	COG0577	efflux transmembrane transporter activity
C7M23_00839	COG5294	Protein conserved in bacteria
C7M23_00840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M23_00846	COG0561	phosphatase activity
C7M23_00847	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M23_00848	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M23_00849	COG0456	acetyltransferase
C7M23_00850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M23_00851	COG0765	amino acid transport
C7M23_00852	COG1126	abc transporter atp-binding protein
C7M23_00853	COG1473	amidohydrolase
C7M23_00854	COG2079	MmgE PrpD family protein
C7M23_00855	COG3192	ethanolamine utilization protein
C7M23_00857	COG2390	Transcriptional regulator
C7M23_00858	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7M23_00859	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M23_00860	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7M23_00861	COG0833	amino acid
C7M23_00862	COG0010	Belongs to the arginase family
C7M23_00863	COG1228	amidohydrolase
C7M23_00864	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C7M23_00865	COG2986	histidine ammonia-lyase
C7M23_00867	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M23_00870	COG5444	nuclease activity
C7M23_00878	COG1263	PTS System
C7M23_00878	COG2190	(PTS) system
C7M23_00878	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M23_00879	COG2723	6-phospho-beta-galactosidase activity
C7M23_00880	COG0589	response to stress
C7M23_00881	COG0697	spore germination
C7M23_00882	COG3209	COG3209 Rhs family protein
C7M23_00893	COG3401	FG-GAP repeat protein
C7M23_00893	COG2755	lipolytic protein G-D-S-L family
C7M23_00894	COG0513	Belongs to the DEAD box helicase family
C7M23_00895	COG2270	Major facilitator Superfamily
C7M23_00897	COG3711	transcriptional antiterminator
C7M23_00898	COG2273	Hydrolase Family 16
C7M23_00899	COG2851	Citrate transporter
C7M23_00900	COG0753	catalase activity
C7M23_00900	COG0693	protein deglycase activity
C7M23_00903	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M23_00904	COG0500	methyltransferase
C7M23_00905	COG2610	gluconate transmembrane transporter activity
C7M23_00906	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M23_00907	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M23_00908	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_00909	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M23_00910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M23_00911	COG4894	glucomannan catabolic process
C7M23_00914	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M23_00915	COG2197	response regulator
C7M23_00916	COG4585	Histidine kinase
C7M23_00918	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M23_00920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M23_00921	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_00922	COG2508	Transcriptional regulator
C7M23_00923	COG3842	ATPase activity
C7M23_00924	COG0726	polysaccharide deacetylase
C7M23_00926	COG0501	Belongs to the peptidase M48B family
C7M23_00927	COG3493	citrate carrier protein
C7M23_00928	COG1271	oxidase subunit
C7M23_00929	COG1294	oxidase, subunit
C7M23_00930	COG4988	ABC transporter
C7M23_00931	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M23_00932	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M23_00933	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M23_00934	COG1595	DNA-templated transcription, initiation
C7M23_00938	COG1131	(ABC) transporter
C7M23_00939	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M23_00940	COG2814	Major facilitator Superfamily
C7M23_00941	COG0753	catalase activity
C7M23_00942	COG2094	Belongs to the DNA glycosylase MPG family
C7M23_00944	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M23_00944	COG3711	transcriptional antiterminator
C7M23_00945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M23_00946	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M23_00947	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M23_00948	COG1486	melibiose metabolic process
C7M23_00949	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M23_00950	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7M23_00951	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M23_00952	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M23_00953	COG1696	Membrane protein involved in D-alanine export
C7M23_00954	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_00955	COG1575	Belongs to the MenA family. Type 1 subfamily
C7M23_00956	COG2357	RelA SpoT domain protein
C7M23_00957	COG2814	Major facilitator Superfamily
C7M23_00960	COG2234	aminopeptidase activity
C7M23_00961	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M23_00962	COG1846	Transcriptional regulator
C7M23_00963	COG5522	Integral membrane protein (intg_mem_TP0381)
C7M23_00964	COG1442	glycosyl transferase family 8
C7M23_00965	COG3711	transcriptional antiterminator
C7M23_00966	COG1263	PTS System
C7M23_00966	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M23_00967	COG1404	Belongs to the peptidase S8 family
C7M23_00968	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M23_00969	COG0346	lactoylglutathione lyase activity
C7M23_00970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M23_00971	COG4895	conserved protein (DUF2196)
C7M23_00972	COG2814	Major facilitator Superfamily
C7M23_00973	COG1346	cytolysis
C7M23_00974	COG1380	Effector of murein hydrolase LrgA
C7M23_00975	COG0583	DNA-binding transcription factor activity
C7M23_00976	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7M23_00977	COG0352	thiamine-phosphate diphosphorylase activity
C7M23_00978	COG0672	)-iron permease
C7M23_00979	COG2822	iron ion transport
C7M23_00980	COG2837	iron assimilation
C7M23_00981	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M23_00982	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M23_00983	COG3162	membrane
C7M23_00985	COG1309	transcriptional regulator
C7M23_00986	COG2246	polysaccharide biosynthetic process
C7M23_00987	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M23_00988	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M23_00989	COG2261	transglycosylase associated protein
C7M23_00990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M23_00991	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M23_00992	COG1845	cytochrome c oxidase, subunit III
C7M23_00993	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M23_00995	COG0772	Belongs to the SEDS family
C7M23_00996	COG0778	Nitroreductase
C7M23_00997	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M23_00998	COG1404	Belongs to the peptidase S8 family
C7M23_01000	COG3711	transcriptional antiterminator
C7M23_01001	COG2116	formate transmembrane transporter activity
C7M23_01002	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M23_01002	COG1263	PTS System
C7M23_01003	COG1621	beta-fructofuranosidase activity
C7M23_01005	COG0351	phosphomethylpyrimidine kinase
C7M23_01006	COG1695	Transcriptional regulator
C7M23_01009	COG1216	Glycosyl transferase, family 2
C7M23_01010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7M23_01011	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_01013	COG2233	PERMEase
C7M23_01014	COG2363	Small membrane protein
C7M23_01017	COG0463	Glycosyl transferase, family 2
C7M23_01018	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M23_01019	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M23_01020	COG0456	acetyltransferase
C7M23_01021	COG2089	acid synthase
C7M23_01022	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C7M23_01023	COG3980	spore coat polysaccharide biosynthesis protein
C7M23_01024	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C7M23_01025	COG1088	dTDP-glucose 4,6-dehydratase activity
C7M23_01026	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7M23_01027	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C7M23_01029	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M23_01030	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_01031	COG4187	Peptidase family M20/M25/M40
C7M23_01032	COG0833	amino acid
C7M23_01033	COG2814	Major facilitator Superfamily
C7M23_01034	COG0077	Prephenate dehydratase
C7M23_01035	COG1917	Cupin 2, conserved barrel domain protein
C7M23_01036	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_01037	COG0151	Belongs to the GarS family
C7M23_01038	COG2814	Major facilitator Superfamily
C7M23_01039	COG0436	Aminotransferase
C7M23_01040	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_01042	COG0280	phosphate acetyltransferase
C7M23_01043	COG0583	DNA-binding transcription factor activity
C7M23_01044	COG0095	Lipoate-protein ligase
C7M23_01045	COG0697	spore germination
C7M23_01047	COG4844	belongs to the
C7M23_01048	COG1078	dGTPase activity
C7M23_01049	COG3465	dGTPase activity
C7M23_01050	COG1959	2 iron, 2 sulfur cluster binding
C7M23_01051	COG0477	Major facilitator Superfamily
C7M23_01053	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M23_01054	COG1846	Transcriptional regulator
C7M23_01055	COG1942	4-Oxalocrotonate Tautomerase
C7M23_01056	COG1994	Peptidase M50
C7M23_01058	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M23_01059	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7M23_01060	COG0010	Belongs to the arginase family
C7M23_01062	COG1131	(ABC) transporter
C7M23_01068	COG0457	Tetratricopeptide repeat
C7M23_01069	COG3391	amine dehydrogenase activity
C7M23_01070	COG3391	amine dehydrogenase activity
C7M23_01072	COG0612	Peptidase, M16
C7M23_01073	COG0612	Peptidase, M16
C7M23_01074	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M23_01075	COG1131	(ABC) transporter
C7M23_01077	COG0535	radical SAM domain protein
C7M23_01079	COG4506	Protein conserved in bacteria
C7M23_01080	COG0018	arginyl-trna synthetase
C7M23_01081	COG2223	nitrite transmembrane transporter activity
C7M23_01082	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M23_01084	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M23_01085	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M23_01086	COG1140	nitrate reductase beta subunit
C7M23_01087	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7M23_01088	COG2181	nitrate reductase activity
C7M23_01089	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M23_01090	COG1132	(ABC) transporter
C7M23_01091	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M23_01093	COG4294	response to UV
C7M23_01094	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M23_01095	COG2181	nitrate reductase activity
C7M23_01095	COG0247	lactate metabolic process
C7M23_01096	COG1960	acyl-CoA dehydrogenase activity
C7M23_01097	COG3343	RNA polymerase activity
C7M23_01098	COG0504	CTP synthase activity
C7M23_01099	COG4821	SIS domain
C7M23_01100	COG2204	response regulator
C7M23_01101	COG0191	fructose-bisphosphate aldolase activity
C7M23_01102	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7M23_01103	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M23_01104	COG1494	fructose-1,6-bisphosphatase
C7M23_01105	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M23_01107	COG1435	thymidine kinase activity
C7M23_01108	COG0281	malic enzyme
C7M23_01109	COG0679	Auxin Efflux Carrier
C7M23_01110	COG0789	Transcriptional regulator
C7M23_01111	COG0346	lactoylglutathione lyase activity
C7M23_01112	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M23_01113	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M23_01117	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7M23_01118	COG0009	L-threonylcarbamoyladenylate synthase
C7M23_01119	COG1971	Probably functions as a manganese efflux pump
C7M23_01120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M23_01121	COG0698	ribose 5-phosphate isomerase
C7M23_01122	COG4475	Protein of unknown function (DUF436)
C7M23_01123	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7M23_01124	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7M23_01126	COG0356	it plays a direct role in the translocation of protons across the membrane
C7M23_01128	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7M23_01129	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M23_01130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7M23_01131	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7M23_01132	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7M23_01133	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7M23_01135	COG4836	Membrane
C7M23_01137	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M23_01138	COG2385	sporulation resulting in formation of a cellular spore
C7M23_01139	COG2304	oxidoreductase activity
C7M23_01140	COG2304	oxidoreductase activity
C7M23_01142	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7M23_01143	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7M23_01144	COG0457	Tetratricopeptide repeat
C7M23_01145	COG1994	Peptidase M50
C7M23_01146	COG3237	CsbD-like
C7M23_01147	COG0831	urea catabolic process
C7M23_01148	COG0832	Belongs to the urease beta subunit family
C7M23_01149	COG0804	urea catabolic process
C7M23_01150	COG1959	2 iron, 2 sulfur cluster binding
C7M23_01151	COG2910	NAD(P)H-binding
C7M23_01153	COG0789	Transcriptional regulator
C7M23_01154	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M23_01157	COG1247	-acetyltransferase
C7M23_01158	COG0739	heme binding
C7M23_01160	COG0671	phosphoesterase, PA-phosphatase related
C7M23_01161	COG0347	Belongs to the P(II) protein family
C7M23_01162	COG0004	ammonium transporteR
C7M23_01164	COG1335	isochorismatase
C7M23_01165	COG0477	Major facilitator Superfamily
C7M23_01166	COG1953	Uracil, thiamine, allantoin
C7M23_01167	COG3420	alginic acid biosynthetic process
C7M23_01168	COG2814	Major facilitator Superfamily
C7M23_01169	COG1846	Transcriptional regulator
C7M23_01170	COG1609	Transcriptional regulator
C7M23_01171	COG1077	Cell shape determining protein MreB Mrl
C7M23_01172	COG4786	Flagellar basal body rod
C7M23_01173	COG4786	Flagellar basal body rod
C7M23_01174	COG0457	Tetratricopeptide repeat
C7M23_01175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M23_01176	COG1970	mechanosensitive ion channel activity
C7M23_01177	COG2972	Histidine kinase
C7M23_01177	COG0745	RESPONSE REGULATOR receiver
C7M23_01178	COG3764	Sortase (surface protein transpeptidase)
C7M23_01181	COG0629	single-stranded DNA binding
C7M23_01182	COG1349	DNA-binding transcription factor activity
C7M23_01183	COG0561	phosphatase activity
C7M23_01184	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M23_01185	COG4715	Zinc finger, swim domain protein
C7M23_01187	COG3944	biosynthesis protein
C7M23_01188	COG0489	protein tyrosine kinase activity
C7M23_01189	COG4464	protein tyrosine phosphatase activity
C7M23_01190	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M23_01191	COG3878	Protein conserved in bacteria
C7M23_01194	COG5444	nuclease activity
C7M23_01197	COG0583	DNA-binding transcription factor activity
C7M23_01198	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M23_01200	COG2059	Chromate
C7M23_01201	COG2059	Chromate
C7M23_01202	COG1522	sequence-specific DNA binding
C7M23_01203	COG0405	Gamma-glutamyltransferase
C7M23_01205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M23_01207	COG5337	Spore coat protein CotH
C7M23_01210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M23_01211	COG0583	DNA-binding transcription factor activity
C7M23_01212	COG0028	Belongs to the TPP enzyme family
C7M23_01213	COG3527	Alpha-acetolactate decarboxylase
C7M23_01214	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M23_01216	COG3103	Sh3 type 3 domain protein
C7M23_01217	COG1879	ABC-type sugar transport system periplasmic component
C7M23_01218	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7M23_01219	COG1129	ABC transporter
C7M23_01220	COG1869	D-ribose catabolic process
C7M23_01221	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M23_01222	COG1609	Transcriptional regulator
C7M23_01223	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M23_01225	COG2843	Capsule synthesis protein
C7M23_01227	COG0791	NLP P60 protein
C7M23_01228	COG0561	phosphatase activity
C7M23_01229	COG1316	TRANSCRIPTIONal
C7M23_01230	COG2814	Major facilitator Superfamily
C7M23_01232	COG0814	amino acid
C7M23_01233	COG0697	spore germination
C7M23_01234	COG1482	cell wall glycoprotein biosynthetic process
C7M23_01235	COG4193	domain, Protein
C7M23_01244	COG0463	Glycosyl transferase, family 2
C7M23_01245	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M23_01245	COG1215	transferase activity, transferring glycosyl groups
C7M23_01246	COG1682	transport, permease protein
C7M23_01247	COG1134	teichoic acid transport
C7M23_01248	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M23_01252	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M23_01253	COG1316	TRANSCRIPTIONal
C7M23_01255	COG2385	sporulation resulting in formation of a cellular spore
C7M23_01255	COG2247	cell wall binding repeat
C7M23_01256	COG2247	cell wall binding repeat
C7M23_01256	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M23_01259	COG2244	polysaccharide biosynthetic process
C7M23_01260	COG0438	transferase activity, transferring glycosyl groups
C7M23_01260	COG0297	glycogen (starch) synthase activity
C7M23_01261	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M23_01262	COG3307	-O-antigen
C7M23_01263	COG3206	protein involved in exopolysaccharide biosynthesis
C7M23_01264	COG1215	transferase activity, transferring glycosyl groups
C7M23_01265	COG0438	transferase activity, transferring glycosyl groups
C7M23_01266	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M23_01267	COG1316	TRANSCRIPTIONal
C7M23_01268	COG1739	Uncharacterized protein family UPF0029
C7M23_01269	COG4585	Histidine kinase
C7M23_01270	COG2197	response regulator
C7M23_01271	COG1307	EDD domain protein, DegV family
C7M23_01272	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M23_01274	COG1040	competence protein
C7M23_01276	COG2747	anti-sigma28 factor FlgM
C7M23_01277	COG3418	PFAM FlgN family protein
C7M23_01278	COG1256	bacterial-type flagellum assembly
C7M23_01278	COG4786	Flagellar basal body rod
C7M23_01279	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M23_01281	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C7M23_01282	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C7M23_01283	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M23_01284	COG1334	flagellar protein FlaG
C7M23_01285	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7M23_01286	COG1516	flagellar protein fliS
C7M23_01289	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7M23_01290	COG0653	protein targeting
C7M23_01291	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C7M23_01292	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M23_01293	COG2010	Cytochrome c
C7M23_01294	COG2884	Cell division ATP-binding protein ftsE
C7M23_01295	COG2177	Part of the ABC transporter FtsEX involved in
C7M23_01296	COG0793	Belongs to the peptidase S41A family
C7M23_01296	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_01298	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M23_01299	COG2814	Major facilitator Superfamily
C7M23_01300	COG1309	transcriptional regulator
C7M23_01301	COG3848	Pyruvate phosphate dikinase
C7M23_01301	COG0574	Belongs to the PEP-utilizing enzyme family
C7M23_01302	COG4897	Protein conserved in bacteria
C7M23_01303	COG0556	nucleotide-excision repair
C7M23_01304	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M23_01305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M23_01306	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M23_01309	COG3595	metallopeptidase activity
C7M23_01310	COG1983	PspC domain protein
C7M23_01311	COG1950	PFAM Membrane protein of
C7M23_01312	COG2814	Major facilitator Superfamily
C7M23_01313	COG1846	Transcriptional regulator
C7M23_01315	COG2124	cytochrome p450
C7M23_01316	COG1846	Transcriptional regulator
C7M23_01317	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M23_01318	COG2188	Transcriptional regulator
C7M23_01319	COG0363	glucosamine-6-phosphate deaminase activity
C7M23_01320	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7M23_01321	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7M23_01322	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7M23_01323	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7M23_01324	COG0546	phosphoglycolate phosphatase activity
C7M23_01325	COG0110	maltose O-acetyltransferase activity
C7M23_01326	COG5297	Belongs to the glycosyl hydrolase family 6
C7M23_01327	COG4990	cell redox homeostasis
C7M23_01328	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7M23_01329	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7M23_01330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M23_01331	COG0131	Imidazoleglycerol-phosphate dehydratase
C7M23_01332	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7M23_01333	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7M23_01334	COG0107	imidazoleglycerol-phosphate synthase activity
C7M23_01335	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M23_01335	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M23_01343	COG1132	(ABC) transporter
C7M23_01344	COG0457	Tetratricopeptide repeat
C7M23_01345	COG3883	PFAM NLP P60 protein
C7M23_01345	COG0791	NLP P60 protein
C7M23_01346	COG0492	ferredoxin-NADP+ reductase activity
C7M23_01347	COG1051	belongs to the nudix hydrolase family
C7M23_01348	COG1660	Displays ATPase and GTPase activities
C7M23_01349	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M23_01350	COG1481	regulation of sporulation
C7M23_01351	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M23_01352	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7M23_01354	COG0745	RESPONSE REGULATOR receiver
C7M23_01355	COG5002	protein histidine kinase activity
C7M23_01356	COG1136	(ABC) transporter
C7M23_01357	COG0577	efflux transmembrane transporter activity
C7M23_01358	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M23_01359	COG0288	reversible hydration of carbon dioxide
C7M23_01360	COG0659	secondary active sulfate transmembrane transporter activity
C7M23_01361	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M23_01362	COG1611	Belongs to the LOG family
C7M23_01363	COG1609	Transcriptional regulator
C7M23_01365	COG2182	Extracellular solute-binding protein
C7M23_01366	COG1175	transmembrane transport
C7M23_01367	COG3833	ABC-type maltose transport systems, permease component
C7M23_01368	COG5521	maltodextrose utilization protein MalA
C7M23_01369	COG1554	hydrolase, family 65, central catalytic
C7M23_01370	COG0366	Alpha amylase catalytic
C7M23_01371	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M23_01372	COG0740	serine-type endopeptidase activity
C7M23_01374	COG3621	Patatin-like phospholipase
C7M23_01375	COG0277	FAD linked oxidase domain protein
C7M23_01377	COG2076	Multidrug Resistance protein
C7M23_01378	COG2076	Multidrug Resistance protein
C7M23_01379	COG1309	transcriptional regulator
C7M23_01380	COG0531	amino acid
C7M23_01381	COG1621	beta-fructofuranosidase activity
C7M23_01382	COG1621	beta-fructofuranosidase activity
C7M23_01383	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M23_01384	COG1794	racemase activity, acting on amino acids and derivatives
C7M23_01386	COG3479	Phenolic acid decarboxylase
C7M23_01388	COG2272	Belongs to the type-B carboxylesterase lipase family
C7M23_01389	COG1396	sequence-specific DNA binding
C7M23_01390	COG3944	biosynthesis protein
C7M23_01391	COG0489	protein tyrosine kinase activity
C7M23_01392	COG1086	Polysaccharide biosynthesis protein
C7M23_01393	COG0438	transferase activity, transferring glycosyl groups
C7M23_01394	COG1215	transferase activity, transferring glycosyl groups
C7M23_01395	COG0438	transferase activity, transferring glycosyl groups
C7M23_01397	COG1216	Glycosyl transferase, family 2
C7M23_01398	COG5039	Polysaccharide pyruvyl transferase
C7M23_01399	COG1216	Glycosyl transferase, family 2
C7M23_01400	COG2244	polysaccharide biosynthetic process
C7M23_01401	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M23_01402	COG0110	maltose O-acetyltransferase activity
C7M23_01403	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M23_01404	COG5039	Polysaccharide pyruvyl transferase
C7M23_01406	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M23_01407	COG1620	l-lactate permease
C7M23_01408	COG2186	Transcriptional regulator
C7M23_01409	COG1609	Transcriptional regulator
C7M23_01410	COG2182	Extracellular solute-binding protein
C7M23_01411	COG1175	transmembrane transport
C7M23_01412	COG3833	ABC-type maltose transport systems, permease component
C7M23_01413	COG1874	Beta-galactosidase
C7M23_01414	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C7M23_01415	COG2208	phosphoserine phosphatase activity
C7M23_01416	COG0596	Alpha beta hydrolase
C7M23_01418	COG1131	(ABC) transporter
C7M23_01419	COG0842	Transport permease protein
C7M23_01420	COG4585	Histidine kinase
C7M23_01421	COG2197	response regulator
C7M23_01422	COG0247	lactate metabolic process
C7M23_01423	COG1139	Iron-sulfur cluster binding protein
C7M23_01424	COG1556	Lactate utilization protein
C7M23_01425	COG3858	chitin binding
C7M23_01426	COG1113	amino acid transport
C7M23_01427	COG0697	spore germination
C7M23_01428	COG0583	DNA-binding transcription factor activity
C7M23_01430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M23_01431	COG1609	Transcriptional regulator
C7M23_01432	COG2814	Major facilitator Superfamily
C7M23_01433	COG2390	Transcriptional regulator
C7M23_01434	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M23_01435	COG0126	phosphoglycerate kinase activity
C7M23_01436	COG0149	triose-phosphate isomerase activity
C7M23_01437	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7M23_01438	COG0148	phosphopyruvate hydratase activity
C7M23_01439	COG0456	acetyltransferase
C7M23_01440	COG4640	response to antibiotic
C7M23_01441	COG3064	Membrane
C7M23_01443	COG2095	MarC family integral membrane protein
C7M23_01444	COG1510	regulation of RNA biosynthetic process
C7M23_01445	COG1125	glycine betaine transport
C7M23_01445	COG0517	IMP dehydrogenase activity
C7M23_01446	COG1174	glycine betaine transport
C7M23_01447	COG1732	Glycine betaine
C7M23_01448	COG1174	glycine betaine transport
C7M23_01449	COG1510	regulation of RNA biosynthetic process
C7M23_01450	COG1125	glycine betaine transport
C7M23_01450	COG0517	IMP dehydrogenase activity
C7M23_01451	COG1174	glycine betaine transport
C7M23_01452	COG1732	Glycine betaine
C7M23_01453	COG1174	glycine betaine transport
C7M23_01454	COG0840	transmembrane signaling receptor activity
C7M23_01455	COG1733	regulation of RNA biosynthetic process
C7M23_01456	COG1396	sequence-specific DNA binding
C7M23_01457	COG1396	sequence-specific DNA binding
C7M23_01458	COG1476	TRANSCRIPTIONal
C7M23_01459	COG0596	Alpha beta hydrolase
C7M23_01460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M23_01461	COG1647	Serine aminopeptidase, S33
C7M23_01462	COG0557	exoribonuclease II activity
C7M23_01463	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7M23_01465	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_01466	COG1309	transcriptional regulator
C7M23_01467	COG2076	Multidrug Resistance protein
C7M23_01469	COG1289	transmembrane transporter activity
C7M23_01470	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M23_01471	COG0673	inositol 2-dehydrogenase activity
C7M23_01472	COG1937	Protein conserved in bacteria
C7M23_01473	COG2608	mercury ion transmembrane transporter activity
C7M23_01474	COG2217	Heavy metal translocating P-type atpase
C7M23_01475	COG2217	Heavy metal translocating P-type atpase
C7M23_01476	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7M23_01477	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M23_01478	COG2860	membrane
C7M23_01480	COG3973	AAA domain
C7M23_01481	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M23_01482	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M23_01483	COG0025	NhaP-type Na H and K H
C7M23_01485	COG0656	L-ascorbic acid biosynthetic process
C7M23_01486	COG4149	molybdate abc transporter
C7M23_01487	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7M23_01488	COG1910	domain protein
C7M23_01489	COG1368	sulfuric ester hydrolase activity
C7M23_01490	COG1988	membrane-bound metal-dependent
C7M23_01492	COG0531	amino acid
C7M23_01493	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M23_01494	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M23_01495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M23_01496	COG1120	ATPase activity
C7M23_01497	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M23_01498	COG1136	(ABC) transporter
C7M23_01499	COG0577	efflux transmembrane transporter activity
C7M23_01501	COG2140	Oxalate decarboxylase
C7M23_01503	COG1191	sigma factor activity
C7M23_01505	COG0745	RESPONSE REGULATOR receiver
C7M23_01506	COG2205	protein histidine kinase activity
C7M23_01507	COG3386	PFAM SMP-30 Gluconolaconase
C7M23_01508	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_01509	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M23_01510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M23_01511	COG1120	ATPase activity
C7M23_01512	COG2096	Adenosyltransferase
C7M23_01513	COG2814	Major facilitator Superfamily
C7M23_01514	COG4758	membrane
C7M23_01515	COG1842	Phage shock protein A
C7M23_01516	COG3595	metallopeptidase activity
C7M23_01517	COG4758	membrane
C7M23_01518	COG4585	Histidine kinase
C7M23_01519	COG2197	response regulator
C7M23_01521	COG0814	amino acid
C7M23_01522	COG0697	spore germination
C7M23_01524	COG0114	fumarate hydratase activity
C7M23_01525	COG1309	transcriptional regulator
C7M23_01526	COG2205	protein histidine kinase activity
C7M23_01526	COG2770	Histidine kinase
C7M23_01527	COG0745	RESPONSE REGULATOR receiver
C7M23_01528	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M23_01529	COG0783	Belongs to the Dps family
C7M23_01530	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_01533	COG1120	ATPase activity
C7M23_01535	COG0583	DNA-binding transcription factor activity
C7M23_01536	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_01537	COG1942	4-Oxalocrotonate Tautomerase
C7M23_01538	COG0477	Major facilitator Superfamily
C7M23_01539	COG1846	Transcriptional regulator
C7M23_01540	COG5577	PFAM Coat F domain
C7M23_01542	COG0506	proline dehydrogenase activity
C7M23_01544	COG1024	Enoyl-CoA hydratase
C7M23_01544	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M23_01545	COG0183	Belongs to the thiolase family
C7M23_01546	COG1960	acyl-CoA dehydrogenase activity
C7M23_01547	COG1393	Belongs to the ArsC family
C7M23_01548	COG0509	glycine decarboxylation via glycine cleavage system
C7M23_01550	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M23_01551	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M23_01553	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M23_01554	COG2011	ABC-type metal ion transport system permease component
C7M23_01555	COG1464	Belongs to the NlpA lipoprotein family
C7M23_01556	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M23_01557	COG0396	ATPase activity
C7M23_01558	COG0719	Fe-S assembly protein
C7M23_01559	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M23_01560	COG0822	iron-sulfur transferase activity
C7M23_01561	COG0719	Fe-S assembly protein
C7M23_01562	COG0346	lactoylglutathione lyase activity
C7M23_01565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M23_01566	COG0322	excinuclease ABC activity
C7M23_01567	COG2222	sugar isomerase
C7M23_01568	COG1653	transport
C7M23_01569	COG1175	transmembrane transport
C7M23_01570	COG0395	ABC-type sugar transport system, permease component
C7M23_01571	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M23_01572	COG2188	Transcriptional regulator
C7M23_01573	COG3842	ATPase activity
C7M23_01574	COG2356	endonuclease I
C7M23_01575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M23_01576	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M23_01578	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7M23_01579	COG2068	MobA-Related Protein
C7M23_01580	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C7M23_01581	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7M23_01582	COG2080	2 iron, 2 sulfur cluster binding
C7M23_01583	COG2351	hydroxyisourate hydrolase activity
C7M23_01584	COG3195	allantoin biosynthetic process
C7M23_01584	COG3648	Uricase
C7M23_01585	COG2233	PERMEase
C7M23_01586	COG2233	PERMEase
C7M23_01587	COG2508	Transcriptional regulator
C7M23_01588	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M23_01590	COG1801	Protein of unknown function DUF72
C7M23_01591	COG0730	response to heat
C7M23_01592	COG0737	Belongs to the 5'-nucleotidase family
C7M23_01593	COG3377	Domain of unknown function (DUF1805)
C7M23_01595	COG0739	heme binding
C7M23_01596	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7M23_01598	COG4470	Protein conserved in bacteria
C7M23_01599	COG2445	Protein of unknown function DUF86
C7M23_01600	COG0647	UMP catabolic process
C7M23_01601	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M23_01602	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M23_01603	COG0460	homoserine dehydrogenase
C7M23_01604	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7M23_01605	COG0083	homoserine kinase activity
C7M23_01606	COG1506	peptidase
C7M23_01606	COG4946	Tricorn protease homolog
C7M23_01606	COG0823	Involved in the tonB-independent uptake of proteins
C7M23_01607	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7M23_01608	COG4837	Protein of unknown function (DUF1462)
C7M23_01609	COG1252	NADH dehydrogenase
C7M23_01610	COG4844	belongs to the
C7M23_01611	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M23_01612	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7M23_01613	COG0316	Belongs to the HesB IscA family
C7M23_01614	COG0456	acetyltransferase
C7M23_01615	COG2808	Putative FMN-binding domain
C7M23_01616	COG0516	GMP reductase activity
C7M23_01618	COG0492	ferredoxin-NADP+ reductase activity
C7M23_01619	COG1252	NADH dehydrogenase
C7M23_01621	COG3584	3D domain protein
C7M23_01622	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7M23_01623	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7M23_01624	COG2056	Na+-H+ antiporter family
C7M23_01625	COG1268	BioY protein
C7M23_01626	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M23_01627	COG2819	hydrolase of the alpha beta superfamily
C7M23_01628	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_01629	COG1169	isochorismate synthase
C7M23_01630	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7M23_01631	COG3433	isochorismatase activity
C7M23_01631	COG1535	isochorismatase
C7M23_01632	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_01633	COG3251	PFAM MbtH domain protein
C7M23_01634	COG5634	Uncharacterized conserved protein (DUF2278)
C7M23_01635	COG0686	Belongs to the AlaDH PNT family
C7M23_01636	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M23_01636	COG2508	Transcriptional regulator
C7M23_01637	COG4842	Belongs to the WXG100 family
C7M23_01638	COG5417	Belongs to the EsaB family
C7M23_01639	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M23_01640	COG0433	COG0433 Predicted ATPase
C7M23_01640	COG1674	ftsk spoiiie
C7M23_01641	COG1511	domain protein
C7M23_01643	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_01644	COG1418	mRNA catabolic process
C7M23_01647	COG0628	permease
C7M23_01650	COG5506	Protein of unknown function (DUF1694)
C7M23_01651	COG1335	isochorismatase
C7M23_01652	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M23_01653	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7M23_01656	COG0142	geranyltranstransferase activity
C7M23_01658	COG4585	Histidine kinase
C7M23_01659	COG2197	response regulator
C7M23_01660	COG2050	protein possibly involved in aromatic compounds catabolism
C7M23_01661	COG1320	monovalent cation:proton antiporter activity
C7M23_01662	COG2212	antiporter activity
C7M23_01663	COG1863	multisubunit Na H antiporter MnhE subunit
C7M23_01664	COG0651	ATP synthesis coupled electron transport
C7M23_01665	COG1006	Multisubunit Na H antiporter MnhC subunit
C7M23_01666	COG2111	Na H antiporter
C7M23_01667	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M23_01667	COG2111	Na H antiporter
C7M23_01669	COG3493	citrate carrier protein
C7M23_01674	COG4565	transcriptional regulatory protein
C7M23_01675	COG3290	protein histidine kinase activity
C7M23_01677	COG3011	Protein conserved in bacteria
C7M23_01678	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M23_01679	COG2814	Major facilitator Superfamily
C7M23_01681	COG5018	Exonuclease
C7M23_01683	COG2205	protein histidine kinase activity
C7M23_01684	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M23_01686	COG2267	carboxylic ester hydrolase activity
C7M23_01687	COG1522	sequence-specific DNA binding
C7M23_01688	COG0436	Aminotransferase
C7M23_01689	COG1098	S1 RNA binding domain
C7M23_01690	COG2155	Conserved Protein
C7M23_01691	COG1979	alcohol dehydrogenase
C7M23_01692	COG1979	alcohol dehydrogenase
C7M23_01693	COG0166	Belongs to the GPI family
C7M23_01696	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M23_01699	COG2738	Putative neutral zinc metallopeptidase
C7M23_01700	COG1253	flavin adenine dinucleotide binding
C7M23_01701	COG0366	Alpha amylase catalytic
C7M23_01702	COG0432	Pfam Uncharacterised protein family UPF0047
C7M23_01705	COG0840	transmembrane signaling receptor activity
C7M23_01706	COG0840	transmembrane signaling receptor activity
C7M23_01707	COG0840	transmembrane signaling receptor activity
C7M23_01708	COG0840	transmembrane signaling receptor activity
C7M23_01709	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_01709	COG3347	Dehydrogenase
C7M23_01710	COG1349	DNA-binding transcription factor activity
C7M23_01711	COG1070	Carbohydrate kinase
C7M23_01712	COG3254	rhamnose metabolic process
C7M23_01713	COG4806	L-rhamnose isomerase
C7M23_01714	COG0673	inositol 2-dehydrogenase activity
C7M23_01715	COG0628	permease
C7M23_01716	COG1968	undecaprenyl-diphosphatase activity
C7M23_01718	COG5553	Cysteine dioxygenase type I
C7M23_01719	COG0477	Major facilitator Superfamily
C7M23_01720	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M23_01721	COG4682	membrane
C7M23_01722	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M23_01723	COG0569	domain protein
C7M23_01725	COG1510	regulation of RNA biosynthetic process
C7M23_01726	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_01727	COG1454	alcohol dehydrogenase
C7M23_01729	COG2318	DinB family
C7M23_01730	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7M23_01731	COG2268	Band 7 protein
C7M23_01732	COG1247	-acetyltransferase
C7M23_01733	COG3859	Proton-coupled thiamine transporter YuaJ
C7M23_01758	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7M23_01759	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M23_01760	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M23_01761	COG0297	glycogen (starch) synthase activity
C7M23_01762	COG0058	SHG alpha-glucan phosphorylase activity
C7M23_01763	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M23_01764	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M23_01765	COG0438	transferase activity, transferring glycosyl groups
C7M23_01766	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M23_01768	COG0438	transferase activity, transferring glycosyl groups
C7M23_01769	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M23_01770	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M23_01771	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M23_01772	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M23_01773	COG1169	isochorismate synthase
C7M23_01774	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7M23_01775	COG0596	Alpha beta hydrolase
C7M23_01776	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7M23_01777	COG0318	PFAM AMP-dependent synthetase and ligase
C7M23_01778	COG4948	Mandelate Racemase Muconate Lactonizing
C7M23_01779	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M23_01780	COG1121	(ABC) transporter
C7M23_01781	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M23_01781	COG1321	iron dependent repressor
C7M23_01782	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M23_01784	COG1294	oxidase, subunit
C7M23_01785	COG1271	oxidase subunit
C7M23_01786	COG0254	rRNA binding
C7M23_01787	COG0288	reversible hydration of carbon dioxide
C7M23_01788	COG1854	S-ribosylhomocysteine lyase activity
C7M23_01791	COG0783	Belongs to the Dps family
C7M23_01792	COG4824	toxin secretion phage lysis holin
C7M23_01793	COG0494	nUDIX hydrolase
C7M23_01794	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M23_01795	COG1116	anion transmembrane transporter activity
C7M23_01796	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M23_01797	COG1506	peptidase
C7M23_01799	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7M23_01800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7M23_01801	COG0367	asparagine synthase
C7M23_01802	COG1113	amino acid transport
C7M23_01803	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M23_01804	COG2267	carboxylic ester hydrolase activity
C7M23_01806	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M23_01807	COG1242	4 iron, 4 sulfur cluster binding
C7M23_01810	COG1725	Transcriptional regulator
C7M23_01811	COG1131	(ABC) transporter
C7M23_01814	COG1136	(ABC) transporter
C7M23_01815	COG0577	efflux transmembrane transporter activity
C7M23_01816	COG0745	RESPONSE REGULATOR receiver
C7M23_01817	COG2205	protein histidine kinase activity
C7M23_01818	COG1136	(ABC) transporter
C7M23_01819	COG0577	efflux transmembrane transporter activity
C7M23_01820	COG2433	Pfam Transposase IS66
C7M23_01821	COG2814	Major facilitator Superfamily
C7M23_01822	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M23_01822	COG2202	Pas domain
C7M23_01824	COG0495	leucyl-tRNA aminoacylation
C7M23_01825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M23_01826	COG1486	melibiose metabolic process
C7M23_01827	COG0395	ABC-type sugar transport system, permease component
C7M23_01828	COG1175	transmembrane transport
C7M23_01829	COG1653	transport
C7M23_01830	COG1609	Transcriptional regulator
C7M23_01831	COG1073	alpha beta
C7M23_01833	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M23_01834	COG0156	8-amino-7-oxononanoate synthase activity
C7M23_01836	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7M23_01837	COG2124	cytochrome p450
C7M23_01838	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M23_01839	COG0395	ABC-type sugar transport system, permease component
C7M23_01840	COG1653	transport
C7M23_01841	COG2207	Transcriptional regulator
C7M23_01842	COG4209	transmembrane transport
C7M23_01843	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M23_01844	COG1653	transport
C7M23_01845	COG0673	inositol 2-dehydrogenase activity
C7M23_01846	COG5578	integral membrane protein
C7M23_01848	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M23_01849	COG2081	HI0933 family
C7M23_01850	COG2244	polysaccharide biosynthetic process
C7M23_01851	COG1187	pseudouridine synthase activity
C7M23_01852	COG1349	DNA-binding transcription factor activity
C7M23_01853	COG1131	(ABC) transporter
C7M23_01854	COG4473	ABC transporter
C7M23_01855	COG2252	PERMEase
C7M23_01856	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M23_01857	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M23_01858	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M23_01860	COG1597	lipid kinase activity
C7M23_01861	COG1523	belongs to the glycosyl hydrolase 13 family
C7M23_01862	COG0510	thiamine kinase activity
C7M23_01864	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7M23_01865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M23_01866	COG0281	malic enzyme
C7M23_01867	COG5584	Small secreted protein
C7M23_01868	COG1363	Peptidase, m42
C7M23_01870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M23_01871	COG4848	Belongs to the UPF0354 family
C7M23_01872	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M23_01873	COG1674	ftsk spoiiie
C7M23_01874	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7M23_01875	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M23_01876	COG4980	gas vesicle protein
C7M23_01877	COG3118	belongs to the thioredoxin family
C7M23_01878	COG1605	Chorismate mutase
C7M23_01878	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M23_01879	COG1609	Transcriptional regulator
C7M23_01880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M23_01881	COG1360	Flagellar Motor Protein
C7M23_01882	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7M23_01883	COG0517	IMP dehydrogenase activity
C7M23_01884	COG0454	-acetyltransferase
C7M23_01885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M23_01886	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M23_01888	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7M23_01889	COG2199	diguanylate cyclase activity
C7M23_01889	COG2203	Gaf domain
C7M23_01890	COG1956	GAF domain-containing protein
C7M23_01891	COG1309	transcriptional regulator
C7M23_01892	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M23_01893	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7M23_01894	COG1114	Component of the transport system for branched-chain amino acids
C7M23_01895	COG1104	cysteine desulfurase activity
C7M23_01896	COG0301	tRNA thio-modification
C7M23_01898	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M23_01899	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C7M23_01900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M23_01901	COG0616	signal peptide processing
C7M23_01902	COG1714	RDD family
C7M23_01904	COG3874	Sporulation protein YtfJ
C7M23_01905	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7M23_01906	COG0827	DNA restriction-modification system
C7M23_01907	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M23_01908	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7M23_01909	COG0137	argininosuccinate synthase activity
C7M23_01910	COG0165	Argininosuccinate lyase
C7M23_01912	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_01913	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7M23_01914	COG0583	DNA-binding transcription factor activity
C7M23_01915	COG0454	-acetyltransferase
C7M23_01916	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M23_01917	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M23_01918	COG0765	amino acid transport
C7M23_01919	COG0765	amino acid transport
C7M23_01920	COG1126	abc transporter atp-binding protein
C7M23_01921	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M23_01922	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7M23_01923	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M23_01924	COG0196	riboflavin kinase activity
C7M23_01925	COG1473	amidohydrolase
C7M23_01926	COG0730	response to heat
C7M23_01927	COG4109	DRTGG domain
C7M23_01929	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M23_01933	COG0587	DNA-directed DNA polymerase activity
C7M23_01934	COG0281	malic enzyme
C7M23_01935	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7M23_01936	COG0825	malonyl-CoA metabolic process
C7M23_01937	COG0205	6-phosphofructokinase activity
C7M23_01938	COG0469	pyruvate kinase activity
C7M23_01939	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7M23_01940	COG0628	permease
C7M23_01941	COG2707	UPF0756 membrane protein
C7M23_01942	COG0372	Belongs to the citrate synthase family
C7M23_01943	COG0538	isocitrate dehydrogenase activity
C7M23_01944	COG0039	L-malate dehydrogenase activity
C7M23_01945	COG0745	RESPONSE REGULATOR receiver
C7M23_01946	COG5002	protein histidine kinase activity
C7M23_01947	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M23_01947	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M23_01948	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M23_01949	COG1971	Probably functions as a manganese efflux pump
C7M23_01950	COG0237	dephospho-CoA kinase activity
C7M23_01951	COG0656	L-ascorbic acid biosynthetic process
C7M23_01952	COG2814	Major facilitator Superfamily
C7M23_01953	COG1733	regulation of RNA biosynthetic process
C7M23_01954	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M23_01955	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C7M23_01956	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7M23_01957	COG3611	Membrane attachment protein
C7M23_01958	COG1484	DNA-dependent DNA replication
C7M23_01959	COG0398	Pfam SNARE associated Golgi protein
C7M23_01962	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M23_01963	COG1011	Hydrolase
C7M23_01964	COG3275	phosphorelay sensor kinase activity
C7M23_01965	COG3279	Response regulator of the LytR AlgR family
C7M23_01966	COG1380	Effector of murein hydrolase LrgA
C7M23_01967	COG1346	cytolysis
C7M23_01969	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M23_01970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7M23_01971	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7M23_01972	COG3326	Membrane
C7M23_01974	COG1363	Peptidase, m42
C7M23_01975	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M23_01976	COG2160	L-arabinose isomerase activity
C7M23_01977	COG1069	ribulokinase activity
C7M23_01978	COG0235	Class ii aldolase
C7M23_01979	COG0647	UMP catabolic process
C7M23_01980	COG0371	Dehydrogenase
C7M23_01981	COG1653	transport
C7M23_01982	COG1175	transmembrane transport
C7M23_01983	COG0395	ABC-type sugar transport system, permease component
C7M23_01984	COG3534	alpha-L-arabinofuranosidase
C7M23_01985	COG1966	Carbon starvation protein
C7M23_01986	COG0346	lactoylglutathione lyase activity
C7M23_01987	COG0247	lactate metabolic process
C7M23_01988	COG0277	FAD linked oxidase domain protein
C7M23_01989	COG3835	regulator
C7M23_01991	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M23_01992	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M23_01993	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M23_01993	COG0072	phenylalanine-tRNA ligase activity
C7M23_01994	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M23_01995	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C7M23_01996	COG1286	toxin biosynthetic process
C7M23_01997	COG1796	DNA polymerase
C7M23_01997	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M23_01998	COG1193	negative regulation of DNA recombination
C7M23_01999	COG3766	membrane
C7M23_02000	COG0318	PFAM AMP-dependent synthetase and ligase
C7M23_02001	COG1309	transcriptional regulator
C7M23_02002	COG1024	Enoyl-CoA hydratase
C7M23_02003	COG2086	electron transfer activity
C7M23_02004	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M23_02005	COG3534	alpha-L-arabinofuranosidase
C7M23_02006	COG3118	belongs to the thioredoxin family
C7M23_02007	COG0322	excinuclease ABC activity
C7M23_02008	COG0527	aspartate kinase activity
C7M23_02009	COG1719	4-vinyl reductase, 4VR
C7M23_02010	COG2009	succinate dehydrogenase
C7M23_02011	COG1053	succinate dehydrogenase
C7M23_02012	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7M23_02013	COG0824	Thioesterase
C7M23_02014	COG2197	response regulator
C7M23_02015	COG1846	Transcriptional regulator
C7M23_02016	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M23_02017	COG5401	PFAM Sporulation and spore germination
C7M23_02018	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7M23_02019	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M23_02020	COG0622	Phosphoesterase
C7M23_02022	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
C7M23_02023	COG0454	-acetyltransferase
C7M23_02024	COG0028	Belongs to the TPP enzyme family
C7M23_02025	COG0440	acetolactate synthase activity
C7M23_02026	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7M23_02027	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M23_02028	COG0473	3-isopropylmalate dehydrogenase activity
C7M23_02029	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7M23_02030	COG0066	3-isopropylmalate dehydratase activity
C7M23_02031	COG1477	protein flavinylation
C7M23_02031	COG0457	Tetratricopeptide repeat
C7M23_02032	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7M23_02033	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7M23_02034	COG0470	DNA polymerase III
C7M23_02034	COG1067	ATP-dependent peptidase activity
C7M23_02035	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7M23_02036	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7M23_02038	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7M23_02039	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M23_02040	COG0181	hydroxymethylbilane synthase activity
C7M23_02041	COG1587	Uroporphyrinogen-III synthase
C7M23_02042	COG0113	porphobilinogen synthase activity
C7M23_02043	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M23_02044	COG1388	LysM domain
C7M23_02045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M23_02047	COG0525	valine-tRNA ligase activity
C7M23_02048	COG0285	dihydrofolate synthase activity
C7M23_02049	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M23_02051	COG0424	maF-like protein
C7M23_02052	COG2003	Belongs to the UPF0758 family
C7M23_02053	COG1077	Cell shape determining protein MreB Mrl
C7M23_02055	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7M23_02056	COG0850	regulation of cytokinetic process
C7M23_02057	COG2894	cell division
C7M23_02058	COG0739	heme binding
C7M23_02059	COG1994	Peptidase M50
C7M23_02060	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7M23_02061	COG2868	ribosomal protein
C7M23_02062	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M23_02063	COG3290	protein histidine kinase activity
C7M23_02064	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7M23_02065	COG4492	Belongs to the UPF0735 family
C7M23_02066	COG0077	Prephenate dehydratase
C7M23_02067	COG1827	regulation of RNA biosynthetic process
C7M23_02068	COG1104	cysteine desulfurase activity
C7M23_02069	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7M23_02070	COG0157	Belongs to the NadC ModD family
C7M23_02071	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7M23_02072	COG1388	LysM domain
C7M23_02074	COG0217	transcriptional regulatory protein
C7M23_02075	COG1115	amino acid carrier protein
C7M23_02078	COG2112	serine threonine protein kinase
C7M23_02079	COG0673	inositol 2-dehydrogenase activity
C7M23_02080	COG2814	Major facilitator Superfamily
C7M23_02082	COG0632	four-way junction helicase activity
C7M23_02083	COG2255	four-way junction helicase activity
C7M23_02085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7M23_02086	COG0343	queuine tRNA-ribosyltransferase activity
C7M23_02087	COG1862	Preprotein translocase
C7M23_02089	COG2323	membrane
C7M23_02090	COG2244	polysaccharide biosynthetic process
C7M23_02092	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M23_02092	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M23_02093	COG0490	domain, Protein
C7M23_02094	COG5416	Lipopolysaccharide assembly protein A domain
C7M23_02095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M23_02095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M23_02096	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M23_02097	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M23_02098	COG1490	D-aminoacyl-tRNA deacylase activity
C7M23_02099	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M23_02099	COG3103	Sh3 type 3 domain protein
C7M23_02099	COG4991	sh3 domain protein
C7M23_02101	COG0124	histidyl-tRNA synthetase
C7M23_02102	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7M23_02103	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7M23_02104	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M23_02105	COG1959	2 iron, 2 sulfur cluster binding
C7M23_02106	COG1104	cysteine desulfurase activity
C7M23_02107	COG0482	sulfurtransferase activity
C7M23_02108	COG0457	Tetratricopeptide repeat
C7M23_02109	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M23_02110	COG3881	PFAM PRC-barrel domain
C7M23_02113	COG0765	amino acid transport
C7M23_02114	COG0765	amino acid transport
C7M23_02115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M23_02116	COG1126	abc transporter atp-binding protein
C7M23_02117	COG0628	permease
C7M23_02118	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7M23_02119	COG4472	Bacterial protein of unknown function (DUF965)
C7M23_02120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7M23_02121	COG3906	Belongs to the UPF0473 family
C7M23_02122	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M23_02123	COG4122	O-methyltransferase activity
C7M23_02126	COG0572	uridine kinase
C7M23_02127	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M23_02128	COG0768	penicillin binding
C7M23_02131	COG2226	methyltransferase
C7M23_02132	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7M23_02133	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M23_02134	COG0626	cystathionine gamma-synthase activity
C7M23_02136	COG2427	Protein of unknown function (DUF1641)
C7M23_02137	COG3383	formate dehydrogenase (NAD+) activity
C7M23_02138	COG5609	conserved protein (DUF2294)
C7M23_02139	COG2116	formate transmembrane transporter activity
C7M23_02142	COG2226	methyltransferase
C7M23_02143	COG1309	transcriptional regulator
C7M23_02144	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M23_02144	COG2124	cytochrome p450
C7M23_02146	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M23_02146	COG2755	lipolytic protein G-D-S-L family
C7M23_02148	COG1595	DNA-templated transcription, initiation
C7M23_02149	COG1378	Sugar-specific transcriptional regulator TrmB
C7M23_02150	COG1280	lysine exporter protein (LysE YggA)
C7M23_02151	COG1113	amino acid transport
C7M23_02152	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M23_02152	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7M23_02153	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M23_02154	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M23_02155	COG3715	PTS system
C7M23_02156	COG3716	PTS system mannose fructose sorbose family IID component
C7M23_02157	COG1621	beta-fructofuranosidase activity
C7M23_02158	COG0693	protein deglycase activity
C7M23_02159	COG1064	alcohol dehydrogenase
C7M23_02161	COG0789	Transcriptional regulator
C7M23_02162	COG5577	PFAM Coat F domain
C7M23_02164	COG1063	alcohol dehydrogenase
C7M23_02165	COG5577	PFAM Coat F domain
C7M23_02167	COG0346	lactoylglutathione lyase activity
C7M23_02168	COG4991	sh3 domain protein
C7M23_02169	COG4991	sh3 domain protein
C7M23_02170	COG0596	Alpha beta hydrolase
C7M23_02171	COG5566	PFAM Mor transcription activator
C7M23_02172	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_02173	COG2828	Protein conserved in bacteria
C7M23_02174	COG0583	DNA-binding transcription factor activity
C7M23_02175	COG2851	Citrate transporter
C7M23_02176	COG0667	Aldo Keto reductase
C7M23_02177	COG1595	DNA-templated transcription, initiation
C7M23_02178	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7M23_02181	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M23_02183	COG2070	2-Nitropropane dioxygenase
C7M23_02185	COG2318	DinB family
C7M23_02187	COG1335	isochorismatase
C7M23_02189	COG2124	cytochrome p450
C7M23_02190	COG2732	(Barnase) inhibitor
C7M23_02191	COG1522	sequence-specific DNA binding
C7M23_02192	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C7M23_02193	COG1687	branched-chain amino acid
C7M23_02194	COG1114	Component of the transport system for branched-chain amino acids
C7M23_02195	COG0583	DNA-binding transcription factor activity
C7M23_02196	COG1942	4-Oxalocrotonate Tautomerase
C7M23_02197	COG1230	cation diffusion facilitator family transporter
C7M23_02198	COG2072	flavoprotein involved in K transport
C7M23_02199	COG0583	DNA-binding transcription factor activity
C7M23_02200	COG0697	spore germination
C7M23_02202	COG1253	flavin adenine dinucleotide binding
C7M23_02203	COG0456	acetyltransferase
C7M23_02204	COG2814	Major facilitator Superfamily
C7M23_02205	COG0789	Transcriptional regulator
C7M23_02205	COG4978	Transcriptional regulator
C7M23_02206	COG0662	Cupin 2, conserved barrel domain protein
C7M23_02207	COG1937	Protein conserved in bacteria
C7M23_02208	COG2210	Belongs to the sulfur carrier protein TusA family
C7M23_02209	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M23_02209	COG0425	Belongs to the sulfur carrier protein TusA family
C7M23_02211	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M23_02211	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M23_02212	COG0425	Belongs to the sulfur carrier protein TusA family
C7M23_02213	COG0730	response to heat
C7M23_02215	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M23_02216	COG0454	-acetyltransferase
C7M23_02217	COG2311	Membrane
C7M23_02218	COG0745	RESPONSE REGULATOR receiver
C7M23_02219	COG0642	Histidine kinase
C7M23_02219	COG5002	protein histidine kinase activity
C7M23_02220	COG3223	Belongs to the PsiE family
C7M23_02222	COG2856	Zn peptidase
C7M23_02224	COG0563	adenylate kinase activity
C7M23_02228	COG1484	DNA-dependent DNA replication
C7M23_02232	COG3677	Transposase
C7M23_02235	COG5484	DNA packaging
C7M23_02236	COG1783	phage Terminase large subunit
C7M23_02237	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_02237	COG1388	LysM domain
C7M23_02237	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M23_02239	COG4282	regulation of fungal-type cell wall biogenesis
C7M23_02241	COG5444	nuclease activity
C7M23_02244	COG0457	Tetratricopeptide repeat
C7M23_02245	COG0604	alcohol dehydrogenase
C7M23_02248	COG3209	COG3209 Rhs family protein
C7M23_02250	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7M23_02251	COG0398	Pfam SNARE associated Golgi protein
C7M23_02252	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M23_02252	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_02253	COG2755	lipolytic protein G-D-S-L family
C7M23_02255	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7M23_02256	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M23_02257	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M23_02258	COG1534	Rna-binding protein
C7M23_02259	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7M23_02260	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M23_02261	COG0799	negative regulation of ribosome biogenesis
C7M23_02262	COG2226	methyltransferase
C7M23_02263	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M23_02264	COG1596	polysaccharide export
C7M23_02264	COG1555	photosystem II stabilization
C7M23_02265	COG2131	deaminase
C7M23_02266	COG2333	competence protein COMEC
C7M23_02266	COG0658	competence protein
C7M23_02268	COG1466	dna polymerase III delta subunit
C7M23_02269	COG0268	Binds directly to 16S ribosomal RNA
C7M23_02270	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7M23_02271	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M23_02273	COG0481	GTPase activity
C7M23_02274	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M23_02275	COG1420	regulation of RNA biosynthetic process
C7M23_02276	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7M23_02277	COG0443	Heat shock 70 kDa protein
C7M23_02278	COG0484	heat shock protein binding
C7M23_02279	COG2264	protein methyltransferase activity
C7M23_02280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M23_02281	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M23_02282	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M23_02284	COG1610	YqeY-like protein
C7M23_02285	COG1030	water channel activity
C7M23_02286	COG4864	UPF0365 protein
C7M23_02289	COG0561	phosphatase activity
C7M23_02290	COG1702	phosphate starvation-inducible protein PhoH
C7M23_02292	COG1480	7TM receptor with intracellular HD hydrolase
C7M23_02293	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7M23_02294	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M23_02295	COG0295	cytidine deaminase activity
C7M23_02296	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M23_02298	COG1381	Involved in DNA repair and RecF pathway recombination
C7M23_02299	COG0752	glycyl-tRNA synthetase alpha subunit
C7M23_02300	COG0751	glycine-tRNA ligase activity
C7M23_02301	COG0517	IMP dehydrogenase activity
C7M23_02302	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7M23_02303	COG1671	Belongs to the UPF0178 family
C7M23_02304	COG0358	DNA primase activity
C7M23_02305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M23_02306	COG2010	Cytochrome c
C7M23_02307	COG2384	SAM-dependent methyltransferase
C7M23_02308	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M23_02309	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7M23_02311	COG0513	Belongs to the DEAD box helicase family
C7M23_02312	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7M23_02314	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M23_02315	COG0735	belongs to the Fur family
C7M23_02316	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C7M23_02317	COG4709	membrane
C7M23_02318	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7M23_02319	COG1388	LysM domain
C7M23_02320	COG5521	maltodextrose utilization protein MalA
C7M23_02321	COG2839	Protein conserved in bacteria
C7M23_02322	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M23_02323	COG0477	Major facilitator Superfamily
C7M23_02325	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M23_02326	COG0573	inorganic phosphate transmembrane transporter activity
C7M23_02327	COG0581	inorganic phosphate transmembrane transporter activity
C7M23_02328	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M23_02329	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M23_02330	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M23_02333	COG0438	transferase activity, transferring glycosyl groups
C7M23_02335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M23_02337	COG0705	Rhomboid family
C7M23_02337	COG0457	Tetratricopeptide repeat
C7M23_02338	COG4483	Protein conserved in bacteria
C7M23_02339	COG1940	carbohydrate kinase activity
C7M23_02340	COG1368	sulfuric ester hydrolase activity
C7M23_02341	COG2866	Carboxypeptidase
C7M23_02343	COG0011	TIGRFAM Protein of
C7M23_02345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M23_02347	COG1393	Belongs to the ArsC family
C7M23_02349	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M23_02350	COG1253	flavin adenine dinucleotide binding
C7M23_02351	COG0598	Magnesium transport protein CorA
C7M23_02352	COG0517	IMP dehydrogenase activity
C7M23_02354	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M23_02355	COG1459	type II secretion system
C7M23_02356	COG4537	Required for transformation and DNA binding
C7M23_02357	COG4970	Tfp pilus assembly protein FimT
C7M23_02359	COG4940	Competence protein ComGF
C7M23_02364	COG0681	Belongs to the peptidase S26 family
C7M23_02366	COG1396	sequence-specific DNA binding
C7M23_02369	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M23_02370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7M23_02371	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M23_02372	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M23_02373	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M23_02374	COG0095	Lipoate-protein ligase
C7M23_02375	COG1321	iron dependent repressor
C7M23_02376	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M23_02378	COG3872	metal-dependent enzyme
C7M23_02380	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7M23_02381	COG0006	proline dipeptidase activity
C7M23_02382	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7M23_02384	COG3854	ATPases associated with a variety of cellular activities
C7M23_02392	COG0511	ligase activity, forming carbon-carbon bonds
C7M23_02393	COG0439	Biotin carboxylase
C7M23_02394	COG1302	Protein conserved in bacteria
C7M23_02395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M23_02396	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7M23_02397	COG1570	exodeoxyribonuclease VII activity
C7M23_02398	COG1722	exodeoxyribonuclease VII activity
C7M23_02399	COG0142	geranyltranstransferase activity
C7M23_02400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7M23_02401	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M23_02402	COG1438	arginine binding
C7M23_02403	COG0497	DNA recombination
C7M23_02404	COG0750	zinc metalloprotease
C7M23_02405	COG0745	RESPONSE REGULATOR receiver
C7M23_02407	COG1902	pentaerythritol trinitrate reductase activity
C7M23_02409	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M23_02410	COG0584	glycerophosphoryl diester phosphodiesterase
C7M23_02411	COG0183	Belongs to the thiolase family
C7M23_02412	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M23_02413	COG1960	acyl-CoA dehydrogenase activity
C7M23_02414	COG0372	Belongs to the citrate synthase family
C7M23_02415	COG2079	MmgE PrpD family protein
C7M23_02416	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7M23_02418	COG3829	transcription factor binding
C7M23_02418	COG3290	protein histidine kinase activity
C7M23_02419	COG0280	phosphate acetyltransferase
C7M23_02420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M23_02421	COG3426	butyrate kinase activity
C7M23_02422	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M23_02423	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M23_02424	COG0022	dehydrogenase e1 component
C7M23_02425	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M23_02426	COG0789	Transcriptional regulator
C7M23_02426	COG4978	Transcriptional regulator
C7M23_02427	COG2814	Major facilitator Superfamily
C7M23_02428	COG1597	lipid kinase activity
C7M23_02430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M23_02431	COG0765	amino acid transport
C7M23_02432	COG1126	abc transporter atp-binding protein
C7M23_02433	COG4129	membrane
C7M23_02434	COG1376	ErfK ybiS ycfS ynhG family protein
C7M23_02436	COG0346	lactoylglutathione lyase activity
C7M23_02437	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M23_02438	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M23_02439	COG3361	conserved protein (COG2071)
C7M23_02440	COG0706	membrane insertase activity
C7M23_02442	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M23_02443	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M23_02444	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M23_02445	COG1234	tRNA 3'-trailer cleavage
C7M23_02447	COG0596	Alpha beta hydrolase
C7M23_02448	COG1902	pentaerythritol trinitrate reductase activity
C7M23_02449	COG4187	Peptidase family M20/M25/M40
C7M23_02450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M23_02451	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M23_02452	COG0300	oxidoreductase activity
C7M23_02453	COG3048	D-serine ammonia-lyase activity
C7M23_02454	COG1072	(Pantothenic acid kinase))
C7M23_02455	COG0346	lactoylglutathione lyase activity
C7M23_02457	COG2211	Major facilitator Superfamily
C7M23_02459	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M23_02461	COG0456	acetyltransferase
C7M23_02462	COG2329	Antibiotic biosynthesis monooxygenase
C7M23_02463	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M23_02463	COG0456	acetyltransferase
C7M23_02464	COG4918	Iron-sulphur cluster biosynthesis
C7M23_02466	COG1073	alpha beta
C7M23_02468	COG0667	Aldo Keto reductase
C7M23_02470	COG0494	nUDIX hydrolase
C7M23_02471	COG1379	DNA repair
C7M23_02472	COG1396	sequence-specific DNA binding
C7M23_02473	COG0252	asparaginase activity
C7M23_02474	COG1027	Aspartate ammonia-lyase
C7M23_02475	COG1757	Na H antiporter
C7M23_02476	COG0281	malic enzyme
C7M23_02478	COG1300	Membrane
C7M23_02479	COG0735	belongs to the Fur family
C7M23_02481	COG4974	Belongs to the 'phage' integrase family
C7M23_02482	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M23_02483	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7M23_02484	COG1686	Belongs to the peptidase S11 family
C7M23_02485	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M23_02486	COG2172	sigma factor antagonist activity
C7M23_02487	COG1191	sigma factor activity
C7M23_02491	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M23_02494	COG0697	spore germination
C7M23_02495	COG0019	diaminopimelate decarboxylase activity
C7M23_02496	COG4086	secreted protein
C7M23_02497	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M23_02502	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M23_02508	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
C7M23_02509	COG0681	Belongs to the peptidase S26 family
C7M23_02511	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M23_02511	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M23_02512	COG0307	riboflavin synthase, alpha
C7M23_02513	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M23_02513	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M23_02514	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7M23_02515	COG0456	acetyltransferase
C7M23_02516	COG1547	Domain of unknown function (DUF309)
C7M23_02517	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7M23_02518	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7M23_02520	COG1686	Belongs to the peptidase S11 family
C7M23_02521	COG2715	membrane protein required for spore maturation
C7M23_02522	COG0700	Nucleoside recognition
C7M23_02523	COG1187	pseudouridine synthase activity
C7M23_02524	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M23_02525	COG1333	cytochrome c biogenesis protein
C7M23_02526	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M23_02527	COG0745	RESPONSE REGULATOR receiver
C7M23_02528	COG5002	protein histidine kinase activity
C7M23_02529	COG1595	DNA-templated transcription, initiation
C7M23_02531	COG0710	3-dehydroquinate dehydratase activity
C7M23_02532	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M23_02533	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M23_02534	COG1141	Ferredoxin
C7M23_02535	COG4955	Helix-turn-helix domain
C7M23_02536	COG0514	ATP-dependent DNA helicase (RecQ)
C7M23_02537	COG1266	CAAX protease self-immunity
C7M23_02538	COG1388	LysM domain
C7M23_02540	COG1408	metallophosphoesterase
C7M23_02541	COG4862	establishment of competence for transformation
C7M23_02542	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M23_02543	COG0492	ferredoxin-NADP+ reductase activity
C7M23_02544	COG2339	peptidase activity
C7M23_02545	COG3773	Cell wall hydrolase
C7M23_02545	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_02546	COG2959	enzyme of heme biosynthesis
C7M23_02547	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7M23_02549	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7M23_02550	COG0539	negative regulation of cytoplasmic translation
C7M23_02551	COG1304	FMN binding
C7M23_02556	COG1160	GTP binding
C7M23_02557	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7M23_02560	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M23_02561	COG0776	regulation of translation
C7M23_02562	COG0302	gtp cyclohydrolase
C7M23_02564	COG0142	geranyltranstransferase activity
C7M23_02565	COG2226	methyltransferase
C7M23_02566	COG0142	geranyltranstransferase activity
C7M23_02567	COG0105	UTP biosynthetic process
C7M23_02568	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7M23_02569	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7M23_02570	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7M23_02571	COG4401	Chorismate mutase type I
C7M23_02572	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M23_02573	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M23_02575	COG0135	phosphoribosylanthranilate isomerase activity
C7M23_02576	COG0133	tryptophan synthase activity
C7M23_02577	COG0159	tryptophan synthase activity
C7M23_02579	COG0287	Prephenate dehydrogenase
C7M23_02580	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7M23_02581	COG0457	Tetratricopeptide repeat
C7M23_02582	COG5582	Belongs to the UPF0302 family
C7M23_02584	COG0723	plastoquinol--plastocyanin reductase activity
C7M23_02585	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M23_02586	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M23_02586	COG2010	Cytochrome c
C7M23_02587	COG4347	Protein of unknown function (DUF1405)
C7M23_02589	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M23_02590	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M23_02591	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7M23_02592	COG1803	Methylglyoxal synthase
C7M23_02593	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M23_02594	COG0438	transferase activity, transferring glycosyl groups
C7M23_02595	COG0617	tRNA 3'-terminal CCA addition
C7M23_02596	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C7M23_02596	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C7M23_02597	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7M23_02598	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7M23_02599	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7M23_02600	COG1199	ATP-dependent helicase activity
C7M23_02600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M23_02602	COG5353	protein conserved in bacteria
C7M23_02603	COG0436	Aminotransferase
C7M23_02604	COG0017	Asparaginyl-tRNA synthetase
C7M23_02605	COG3935	DnaD domain protein
C7M23_02606	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M23_02608	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M23_02608	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M23_02609	COG3331	DNA recombination
C7M23_02616	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M23_02617	COG2190	(PTS) system
C7M23_02618	COG1111	helicase
C7M23_02618	COG1205	dead DEAH box helicase
C7M23_02619	COG3359	exonuclease
C7M23_02620	COG4474	Belongs to the UPF0398 family
C7M23_02622	COG0116	Belongs to the methyltransferase superfamily
C7M23_02624	COG1199	ATP-dependent helicase activity
C7M23_02625	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_02626	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C7M23_02627	COG1609	Transcriptional regulator
C7M23_02628	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M23_02629	COG0800	Aldolase
C7M23_02631	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7M23_02632	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M23_02633	COG2233	PERMEase
C7M23_02634	COG3424	synthase
C7M23_02635	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7M23_02636	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M23_02639	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M23_02641	COG0328	RNA-DNA hybrid ribonuclease activity
C7M23_02642	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7M23_02643	COG0328	RNA-DNA hybrid ribonuclease activity
C7M23_02647	COG1278	Cold shock
C7M23_02648	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M23_02650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7M23_02651	COG0386	Belongs to the glutathione peroxidase family
C7M23_02652	COG1418	mRNA catabolic process
C7M23_02653	COG1413	lyase activity
C7M23_02654	COG0129	dihydroxy-acid dehydratase activity
C7M23_02656	COG2136	Putative SAM-dependent methyltransferase
C7M23_02656	COG2521	methyltransferase
C7M23_02658	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M23_02659	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7M23_02660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M23_02661	COG0204	Acyl-transferase
C7M23_02662	COG1272	protein, Hemolysin III
C7M23_02663	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M23_02664	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M23_02666	COG1999	signal sequence binding
C7M23_02667	COG2755	lipolytic protein G-D-S-L family
C7M23_02668	COG4698	Protein conserved in bacteria
C7M23_02670	COG0534	Mate efflux family protein
C7M23_02671	COG1846	Transcriptional regulator
C7M23_02672	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M23_02673	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M23_02674	COG1086	Polysaccharide biosynthesis protein
C7M23_02675	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
C7M23_02676	COG4641	Protein conserved in bacteria
C7M23_02679	COG0463	Glycosyl transferase, family 2
C7M23_02680	COG0456	acetyltransferase
C7M23_02682	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M23_02683	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M23_02684	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M23_02685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M23_02686	COG0456	acetyltransferase
C7M23_02687	COG1509	lysine 2,3-aminomutase activity
C7M23_02689	COG4479	Belongs to the UPF0346 family
C7M23_02693	COG0671	phosphoesterase, PA-phosphatase related
C7M23_02696	COG0813	purine-nucleoside phosphorylase activity
C7M23_02697	COG1876	peptidase activity
C7M23_02699	COG2226	methyltransferase
C7M23_02700	COG0793	Belongs to the peptidase S41A family
C7M23_02700	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_02701	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M23_02703	COG0346	lactoylglutathione lyase activity
C7M23_02704	COG0400	carboxylic ester hydrolase activity
C7M23_02705	COG0778	Nitroreductase
C7M23_02706	COG1733	regulation of RNA biosynthetic process
C7M23_02707	COG1942	4-Oxalocrotonate Tautomerase
C7M23_02708	COG2610	gluconate transmembrane transporter activity
C7M23_02711	COG2962	Rard protein
C7M23_02713	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M23_02714	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M23_02715	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M23_02716	COG0534	Mate efflux family protein
C7M23_02718	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M23_02719	COG1819	glycosyl
C7M23_02720	COG1388	LysM domain
C7M23_02720	COG0791	NLP P60 protein
C7M23_02721	COG2032	superoxide dismutase activity
C7M23_02722	COG0714	Associated with various cellular activities
C7M23_02723	COG4548	von Willebrand factor, type A
C7M23_02724	COG0567	Dehydrogenase, E1 component
C7M23_02725	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M23_02726	COG0385	Bile acid
C7M23_02727	COG0733	neurotransmitter:sodium symporter activity
C7M23_02728	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M23_02729	COG1657	PFAM Prenyltransferase squalene oxidase
C7M23_02730	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_02735	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M23_02738	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M23_02739	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M23_02740	COG0514	ATP-dependent DNA helicase (RecQ)
C7M23_02741	COG3584	3D domain protein
C7M23_02741	COG1388	LysM domain
C7M23_02742	COG2197	response regulator
C7M23_02743	COG4585	Histidine kinase
C7M23_02744	COG3239	Fatty acid desaturase
C7M23_02745	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M23_02748	COG2322	membrane
C7M23_02749	COG0741	lytic transglycosylase activity
C7M23_02750	COG0640	Transcriptional regulator
C7M23_02752	COG2378	regulation of single-species biofilm formation
C7M23_02753	COG3708	Transcriptional regulator
C7M23_02754	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M23_02755	COG1309	transcriptional regulator
C7M23_02756	COG0456	acetyltransferase
C7M23_02757	COG2207	Transcriptional regulator
C7M23_02757	COG0662	Cupin 2, conserved barrel domain protein
C7M23_02758	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M23_02759	COG1231	oxidoreductase activity
C7M23_02760	COG4282	regulation of fungal-type cell wall biogenesis
C7M23_02761	COG5444	nuclease activity
C7M23_02764	COG0457	Tetratricopeptide repeat
C7M23_02769	COG1404	Belongs to the peptidase S8 family
C7M23_02781	COG0726	polysaccharide deacetylase
C7M23_02782	COG3848	Pyruvate phosphate dikinase
C7M23_02782	COG0574	Belongs to the PEP-utilizing enzyme family
C7M23_02785	COG2367	Beta-lactamase
C7M23_02786	COG0693	protein deglycase activity
C7M23_02788	COG0697	spore germination
C7M23_02789	COG0583	DNA-binding transcription factor activity
C7M23_02790	COG3739	integral membrane protein
C7M23_02791	COG3655	Transcriptional regulator
C7M23_02793	COG2720	vancomycin resistance protein
C7M23_02796	COG0456	acetyltransferase
C7M23_02798	COG2140	Oxalate decarboxylase
C7M23_02800	COG2135	peptidase activity
C7M23_02801	COG3866	Pectate lyase
C7M23_02802	COG3619	membrane
C7M23_02803	COG4305	rare lipoprotein A
C7M23_02804	COG2368	4-hydroxyphenylacetate
C7M23_02805	COG0840	transmembrane signaling receptor activity
C7M23_02805	COG5278	phosphoserine phosphatase activity
C7M23_02809	COG1609	Transcriptional regulator
C7M23_02810	COG1082	Xylose isomerase domain protein TIM barrel
C7M23_02811	COG0673	inositol 2-dehydrogenase activity
C7M23_02812	COG2814	Major facilitator Superfamily
C7M23_02814	COG0243	molybdopterin cofactor binding
C7M23_02815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M23_02816	COG1070	Carbohydrate kinase
C7M23_02817	COG2814	Major facilitator Superfamily
C7M23_02818	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M23_02820	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M23_02821	COG0300	oxidoreductase activity
C7M23_02823	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M23_02824	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M23_02825	COG0583	DNA-binding transcription factor activity
C7M23_02826	COG0069	glutamate synthase activity
C7M23_02826	COG0070	glutamate synthase
C7M23_02826	COG0067	glutamate synthase
C7M23_02827	COG0493	'glutamate synthase
C7M23_02828	COG0604	alcohol dehydrogenase
C7M23_02829	COG0583	DNA-binding transcription factor activity
C7M23_02830	COG0405	Gamma-glutamyltransferase
C7M23_02831	COG0166	Belongs to the GPI family
C7M23_02832	COG0582	viral genome integration into host DNA
C7M23_02835	COG0534	Mate efflux family protein
C7M23_02836	COG2017	converts alpha-aldose to the beta-anomer
C7M23_02837	COG2027	D-alanyl-D-alanine carboxypeptidase
C7M23_02838	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_02839	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_02840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_02841	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_02842	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M23_02842	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_02844	COG1649	PFAM Uncharacterised BCR, COG1649
C7M23_02845	COG1960	acyl-CoA dehydrogenase activity
C7M23_02846	COG0318	PFAM AMP-dependent synthetase and ligase
C7M23_02847	COG0439	Biotin carboxylase
C7M23_02848	COG0511	ligase activity, forming carbon-carbon bonds
C7M23_02849	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M23_02850	COG1024	Enoyl-CoA hydratase
C7M23_02851	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M23_02852	COG2404	hydrolase activity, acting on ester bonds
C7M23_02853	COG0586	Pfam SNARE associated Golgi protein
C7M23_02854	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M23_02855	COG2246	polysaccharide biosynthetic process
C7M23_02856	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M23_02857	COG5520	Belongs to the glycosyl hydrolase 30 family
C7M23_02859	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7M23_02860	COG1115	amino acid carrier protein
C7M23_02863	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M23_02864	COG0187	DNA topoisomerase II activity
C7M23_02865	COG1832	CoA-binding protein
C7M23_02866	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7M23_02867	COG4841	protein insertion into membrane
C7M23_02869	COG0824	Thioesterase
C7M23_02873	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M23_02874	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7M23_02877	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M23_02879	COG4846	Membrane protein involved in cytochrome C biogenesis
C7M23_02880	COG2201	protein-glutamate methylesterase activity
C7M23_02881	COG0785	Cytochrome C biogenesis protein
C7M23_02883	COG3763	UPF0154 protein
C7M23_02885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M23_02886	COG4224	UPF0291 protein
C7M23_02887	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M23_02888	COG1388	LysM domain
C7M23_02889	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7M23_02890	COG0346	lactoylglutathione lyase activity
C7M23_02892	COG4195	phage-related replication protein
C7M23_02898	COG0531	amino acid
C7M23_02899	COG0697	spore germination
C7M23_02902	COG3832	glyoxalase III activity
C7M23_02904	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M23_02913	COG0756	dUTP diphosphatase activity
C7M23_02915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M23_02916	COG2814	Major facilitator Superfamily
C7M23_02917	COG1525	nuclease
C7M23_02918	COG1070	Carbohydrate kinase
C7M23_02919	COG2115	Belongs to the xylose isomerase family
C7M23_02920	COG1940	carbohydrate kinase activity
C7M23_02921	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M23_02922	COG2211	Major facilitator Superfamily
C7M23_02923	COG0135	phosphoribosylanthranilate isomerase activity
C7M23_02927	COG3655	Transcriptional regulator
C7M23_02931	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M23_02933	COG4282	regulation of fungal-type cell wall biogenesis
C7M23_02948	COG5444	nuclease activity
C7M23_02950	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M23_02950	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_02951	COG4824	toxin secretion phage lysis holin
C7M23_02952	COG4824	toxin secretion phage lysis holin
C7M23_02954	COG4974	Belongs to the 'phage' integrase family
C7M23_02955	COG0174	glutamine synthetase
C7M23_02956	COG0789	Transcriptional regulator
C7M23_02957	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7M23_02958	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M23_02959	COG0464	growth
C7M23_02960	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M23_02961	COG4112	unkown
C7M23_02962	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M23_02963	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M23_02964	COG1780	Probably involved in ribonucleotide reductase function
C7M23_02967	COG1923	regulation of RNA biosynthetic process
C7M23_02968	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7M23_02971	COG2076	Multidrug Resistance protein
C7M23_02972	COG2076	Multidrug Resistance protein
C7M23_02973	COG1764	response to oxidative stress
C7M23_02974	COG4195	phage-related replication protein
C7M23_02976	COG1404	Belongs to the peptidase S8 family
C7M23_02977	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M23_02979	COG2124	cytochrome p450
C7M23_02980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M23_02980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7M23_02980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M23_02980	COG3321	synthase
C7M23_02981	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_02981	COG3321	synthase
C7M23_02981	COG4221	oxidoreductase activity
C7M23_02981	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_02982	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_02982	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M23_02982	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_02982	COG3321	synthase
C7M23_02982	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M23_02983	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M23_02983	COG0300	oxidoreductase activity
C7M23_02983	COG3321	synthase
C7M23_02983	COG4221	oxidoreductase activity
C7M23_02984	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M23_02984	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_02984	COG0318	PFAM AMP-dependent synthetase and ligase
C7M23_02984	COG3321	synthase
C7M23_02984	COG0300	oxidoreductase activity
C7M23_02985	COG1024	Enoyl-CoA hydratase
C7M23_02986	COG1024	Enoyl-CoA hydratase
C7M23_02987	COG3425	synthase
C7M23_02988	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M23_02989	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M23_02990	COG2070	2-Nitropropane dioxygenase
C7M23_02990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M23_02991	COG3321	synthase
C7M23_02993	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M23_02994	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M23_02995	COG3226	Transcriptional regulator
C7M23_02998	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7M23_02999	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M23_03001	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7M23_03002	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M23_03003	COG0156	8-amino-7-oxononanoate synthase activity
C7M23_03004	COG1063	alcohol dehydrogenase
C7M23_03005	COG2359	stage V sporulation protein S
C7M23_03006	COG1692	metallophosphoesterase
C7M23_03007	COG1418	mRNA catabolic process
C7M23_03008	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M23_03009	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7M23_03010	COG1058	Belongs to the CinA family
C7M23_03010	COG1546	Belongs to the CinA family
C7M23_03011	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M23_03012	COG1426	Protein conserved in bacteria
C7M23_03015	COG0300	oxidoreductase activity
C7M23_03016	COG0612	Peptidase, M16
C7M23_03017	COG0612	Peptidase, M16
C7M23_03018	COG2814	Major facilitator Superfamily
C7M23_03019	COG2188	Transcriptional regulator
C7M23_03020	COG4980	gas vesicle protein
C7M23_03020	COG1674	ftsk spoiiie
C7M23_03022	COG0740	serine-type endopeptidase activity
C7M23_03023	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M23_03024	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M23_03025	COG0527	aspartate kinase activity
C7M23_03026	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M23_03027	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M23_03028	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M23_03029	COG1873	PFAM PRC-barrel domain
C7M23_03030	COG0612	Peptidase, M16
C7M23_03031	COG0726	polysaccharide deacetylase
C7M23_03032	COG1185	polyribonucleotide nucleotidyltransferase activity
C7M23_03033	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7M23_03034	COG0196	riboflavin kinase activity
C7M23_03035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7M23_03036	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7M23_03037	COG1550	Protein conserved in bacteria
C7M23_03038	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7M23_03039	COG1358	cellular component organization or biogenesis
C7M23_03040	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M23_03041	COG0195	Participates in both transcription termination and antitermination
C7M23_03042	COG0779	Required for maturation of 30S ribosomal subunits
C7M23_03043	COG2176	DNA-directed DNA polymerase activity
C7M23_03044	COG0442	prolyl-tRNA aminoacylation
C7M23_03045	COG0750	zinc metalloprotease
C7M23_03046	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7M23_03047	COG4589	Belongs to the CDS family
C7M23_03048	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M23_03049	COG0233	cytoplasmic translational termination
C7M23_03050	COG0528	UMP kinase activity
C7M23_03051	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7M23_03052	COG0052	Belongs to the universal ribosomal protein uS2 family
C7M23_03054	COG1191	sigma factor activity
C7M23_03055	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C7M23_03056	COG1776	CheC inhibitor of MCP methylation
C7M23_03057	COG0835	chemotaxis
C7M23_03058	COG2198	Histidine kinase
C7M23_03058	COG0643	Histidine kinase
C7M23_03059	COG2201	protein-glutamate methylesterase activity
C7M23_03060	COG0455	bacterial-type flagellum organization
C7M23_03061	COG1419	protein localization to endoplasmic reticulum
C7M23_03062	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M23_03063	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M23_03064	COG1684	flagellar biosynthetic protein fliR
C7M23_03065	COG1987	bacterial-type flagellum assembly
C7M23_03066	COG1338	Plays a role in the flagellum-specific transport system
C7M23_03067	COG3190	flagellar
C7M23_03068	COG2201	protein-glutamate methylesterase activity
C7M23_03069	COG1776	CheC inhibitor of MCP methylation
C7M23_03069	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M23_03070	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M23_03071	COG1580	Controls the rotational direction of flagella during chemotaxis
C7M23_03072	COG4786	Flagellar basal body rod
C7M23_03073	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7M23_03074	COG3144	bacterial-type flagellum assembly
C7M23_03075	COG3334	PFAM MgtE intracellular
C7M23_03076	COG2882	bacterial-type flagellum organization
C7M23_03077	COG1157	protein secretion by the type III secretion system
C7M23_03078	COG1317	bacterial-type flagellum organization
C7M23_03079	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M23_03080	COG1766	The M ring may be actively involved in energy transduction
C7M23_03081	COG1677	Flagellar hook-basal body complex protein FliE
C7M23_03082	COG1558	bacterial-type flagellum-dependent cell motility
C7M23_03083	COG1815	bacterial-type flagellum-dependent cell motility
C7M23_03084	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M23_03085	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7M23_03086	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7M23_03087	COG4974	Belongs to the 'phage' integrase family
C7M23_03088	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7M23_03089	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M23_03090	COG0758	DNA mediated transformation
C7M23_03091	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M23_03092	COG0045	succinate-CoA ligase (ADP-forming) activity
C7M23_03093	COG2257	FlhB HrpN YscU SpaS Family
C7M23_03095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M23_03096	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M23_03097	COG0335	large ribosomal subunit rRNA binding
C7M23_03098	COG0336	Belongs to the RNA methyltransferase TrmD family
C7M23_03099	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7M23_03101	COG1837	Belongs to the UPF0109 family
C7M23_03102	COG0228	four-way junction DNA binding
C7M23_03103	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M23_03104	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7M23_03106	COG0552	protein localization to endoplasmic reticulum
C7M23_03107	COG1196	nuclear chromosome segregation
C7M23_03108	COG0571	ribonuclease III activity
C7M23_03110	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_03111	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M23_03112	COG0416	fatty acid biosynthetic process
C7M23_03113	COG1349	DNA-binding transcription factor activity
C7M23_03113	COG2050	protein possibly involved in aromatic compounds catabolism
C7M23_03114	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M23_03115	COG1760	l-serine dehydratase
C7M23_03116	COG1760	l-serine dehydratase
C7M23_03117	COG1461	Dihydroxyacetone kinase
C7M23_03118	COG1302	Protein conserved in bacteria
C7M23_03119	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7M23_03120	COG1564	THIamine pyrophosphokinase
C7M23_03121	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M23_03122	COG1162	GTPase activity
C7M23_03123	COG0515	serine threonine protein kinase
C7M23_03123	COG2815	serine threonine protein kinase
C7M23_03124	COG0631	protein serine/threonine phosphatase activity
C7M23_03125	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7M23_03126	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M23_03126	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M23_03127	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7M23_03128	COG0242	peptide deformylase activity
C7M23_03129	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M23_03130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M23_03131	COG1758	RNA polymerase activity
C7M23_03132	COG0194	GDP metabolic process
C7M23_03134	COG1561	YicC-like family, N-terminal region
C7M23_03135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M23_03136	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C7M23_03137	COG1648	precorrin-2 dehydrogenase activity
C7M23_03138	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7M23_03139	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M23_03140	COG0529	Catalyzes the synthesis of activated sulfate
C7M23_03141	COG2046	Belongs to the sulfate adenylyltransferase family
C7M23_03142	COG0306	phosphate transporter
C7M23_03143	COG0175	sulfate reduction
C7M23_03145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M23_03146	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M23_03147	COG0167	dihydroorotate dehydrogenase activity
C7M23_03148	COG0543	2 iron, 2 sulfur cluster binding
C7M23_03149	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M23_03150	COG0505	Belongs to the CarA family
C7M23_03151	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M23_03152	COG0540	Belongs to the ATCase OTCase family
C7M23_03153	COG2233	PERMEase
C7M23_03154	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M23_03155	COG0564	pseudouridine synthase activity
C7M23_03156	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7M23_03157	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M23_03158	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M23_03159	COG3599	regulation of cell shape
C7M23_03160	COG2302	S4 RNA-binding domain
C7M23_03161	COG0762	integral membrane protein
C7M23_03162	COG1799	cell septum assembly
C7M23_03163	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7M23_03165	COG1873	PFAM PRC-barrel domain
C7M23_03166	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M23_03167	COG1119	ATPase activity
C7M23_03168	COG1191	sigma factor activity
C7M23_03169	COG1191	sigma factor activity
C7M23_03172	COG4412	M6 family metalloprotease domain protein
C7M23_03172	COG1404	Belongs to the peptidase S8 family
C7M23_03173	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M23_03176	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M23_03177	COG0849	cell division
C7M23_03178	COG3856	small basic protein
C7M23_03179	COG3879	Bacterial protein of unknown function (DUF881)
C7M23_03180	COG3879	Bacterial protein of unknown function (DUF881)
C7M23_03181	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M23_03182	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7M23_03183	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M23_03184	COG0772	Belongs to the SEDS family
C7M23_03185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M23_03186	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M23_03187	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7M23_03188	COG0768	penicillin binding
C7M23_03190	COG4839	cell division protein FtsL
C7M23_03191	COG0275	rRNA processing
C7M23_03192	COG2001	Belongs to the MraZ family
C7M23_03193	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C7M23_03194	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M23_03195	COG0454	-acetyltransferase
C7M23_03198	COG1399	metal-binding, possibly nucleic acid-binding protein
C7M23_03202	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M23_03203	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M23_03204	COG3314	Sporulation integral membrane protein YlbJ
C7M23_03205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7M23_03206	COG0742	ribosomal rna small subunit methyltransferase
C7M23_03207	COG4471	UPF0298 protein
C7M23_03208	COG3679	Belongs to the UPF0342 family
C7M23_03211	COG2340	Cysteine-rich secretory protein family
C7M23_03212	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C7M23_03214	COG3336	cytochrome c oxidase
C7M23_03215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M23_03216	COG1845	cytochrome c oxidase, subunit III
C7M23_03217	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M23_03218	COG2010	Cytochrome c
C7M23_03218	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M23_03219	COG0109	protoheme IX farnesyltransferase activity
C7M23_03220	COG1612	heme a metabolic process
C7M23_03221	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M23_03222	COG0772	Belongs to the SEDS family
C7M23_03223	COG4838	Belongs to the UPF0358 family
C7M23_03224	COG2066	Belongs to the glutaminase family
C7M23_03225	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M23_03226	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7M23_03228	COG4896	Protein conserved in bacteria
C7M23_03234	COG1595	DNA-templated transcription, initiation
C7M23_03238	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7M23_03240	COG0483	inositol monophosphate 1-phosphatase activity
C7M23_03242	COG4493	Belongs to the UPF0637 family
C7M23_03243	COG4476	Belongs to the UPF0223 family
C7M23_03244	COG1982	Orn Lys Arg decarboxylase major
C7M23_03245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M23_03246	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M23_03247	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M23_03248	COG0022	dehydrogenase e1 component
C7M23_03249	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M23_03250	COG0497	DNA recombination
C7M23_03252	COG0242	peptide deformylase activity
C7M23_03253	COG0561	phosphatase activity
C7M23_03255	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M23_03256	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M23_03257	COG0569	domain protein
C7M23_03258	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C7M23_03258	COG2105	PFAM AIG2 family protein
C7M23_03259	COG3852	Histidine kinase
C7M23_03260	COG2002	toxin-antitoxin pair type II binding
C7M23_03261	COG1077	Cell shape determining protein MreB Mrl
C7M23_03263	COG2309	aminopeptidase activity
C7M23_03264	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M23_03265	COG0488	(ABC) transporter
C7M23_03267	COG0681	Belongs to the peptidase S26 family
C7M23_03268	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M23_03268	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M23_03268	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M23_03269	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M23_03270	COG1349	DNA-binding transcription factor activity
C7M23_03271	COG0577	efflux transmembrane transporter activity
C7M23_03272	COG1136	(ABC) transporter
C7M23_03273	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M23_03275	COG1132	(ABC) transporter
C7M23_03276	COG1132	(ABC) transporter
C7M23_03277	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7M23_03278	COG0314	molybdopterin synthase activity
C7M23_03279	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M23_03280	COG0303	'Molybdopterin
C7M23_03281	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M23_03282	COG0746	molybdenum cofactor guanylyltransferase activity
C7M23_03285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M23_03286	COG0450	alkyl hydroperoxide reductase
C7M23_03287	COG0668	transmembrane transport
C7M23_03289	COG1473	amidohydrolase
C7M23_03290	COG2171	N-acyltransferase activity
C7M23_03291	COG0716	FMN binding
C7M23_03293	COG0716	FMN binding
C7M23_03294	COG0583	DNA-binding transcription factor activity
C7M23_03295	COG0517	IMP dehydrogenase activity
C7M23_03297	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C7M23_03298	COG4703	Protein of unknown function (DUF1797)
C7M23_03299	COG2200	EAL domain
C7M23_03301	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_03302	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_03303	COG1408	metallophosphoesterase
C7M23_03304	COG1376	ErfK ybiS ycfS ynhG family protein
C7M23_03305	COG2814	Major facilitator Superfamily
C7M23_03307	COG0784	Response regulator, receiver
C7M23_03307	COG0835	chemotaxis
C7M23_03309	COG0436	Aminotransferase
C7M23_03310	COG4191	Histidine kinase
C7M23_03311	COG0768	penicillin binding
C7M23_03312	COG2340	Cysteine-rich secretory protein family
C7M23_03313	COG2084	Dehydrogenase
C7M23_03314	COG0840	transmembrane signaling receptor activity
C7M23_03315	COG0456	acetyltransferase
C7M23_03316	COG1533	DNA photolyase activity
C7M23_03318	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M23_03319	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M23_03320	COG1263	PTS System
C7M23_03320	COG2190	(PTS) system
C7M23_03320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M23_03321	COG3711	transcriptional antiterminator
C7M23_03323	COG1609	Transcriptional regulator
C7M23_03325	COG0006	proline dipeptidase activity
C7M23_03327	COG2217	Heavy metal translocating P-type atpase
C7M23_03328	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M23_03329	COG2244	polysaccharide biosynthetic process
C7M23_03330	COG3773	Cell wall hydrolase
C7M23_03332	COG4873	Protein conserved in bacteria
C7M23_03334	COG3858	chitin binding
C7M23_03335	COG1388	LysM domain
C7M23_03336	COG1388	LysM domain
C7M23_03336	COG4641	Protein conserved in bacteria
C7M23_03337	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_03338	COG1733	regulation of RNA biosynthetic process
C7M23_03339	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7M23_03340	COG0602	queuosine metabolic process
C7M23_03341	COG0720	synthase
C7M23_03342	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7M23_03343	COG3949	Membrane
C7M23_03344	COG0542	response to heat
C7M23_03345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M23_03346	COG1360	Flagellar Motor Protein
C7M23_03347	COG1846	Transcriptional regulator
C7M23_03348	COG3852	Histidine kinase
C7M23_03351	COG3339	Conserved Protein
C7M23_03352	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C7M23_03353	COG0235	Class ii aldolase
C7M23_03354	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
C7M23_03355	COG1850	ribulose-bisphosphate carboxylase activity
C7M23_03356	COG0436	Aminotransferase
C7M23_03357	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M23_03358	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
C7M23_03359	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C7M23_03361	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M23_03362	COG5002	protein histidine kinase activity
C7M23_03363	COG3594	Acyltransferase
C7M23_03366	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M23_03367	COG0501	Belongs to the peptidase M48B family
C7M23_03371	COG1191	sigma factor activity
C7M23_03372	COG0861	Integral membrane protein TerC family
C7M23_03373	COG0586	Pfam SNARE associated Golgi protein
C7M23_03374	COG5001	Diguanylate cyclase
C7M23_03374	COG3300	MHYT domain
C7M23_03375	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C7M23_03376	COG3285	dna ligase
C7M23_03376	COG1793	dna ligase
C7M23_03377	COG0463	Glycosyl transferase, family 2
C7M23_03379	COG1408	metallophosphoesterase
C7M23_03380	COG0726	polysaccharide deacetylase
C7M23_03381	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M23_03382	COG1846	Transcriptional regulator
C7M23_03385	COG0789	Transcriptional regulator
C7M23_03386	COG2239	Acts as a magnesium transporter
C7M23_03389	COG3212	peptidase
C7M23_03390	COG3212	peptidase
C7M23_03391	COG5002	protein histidine kinase activity
C7M23_03391	COG3850	Histidine kinase
C7M23_03392	COG0745	RESPONSE REGULATOR receiver
C7M23_03394	COG4721	ABC-type cobalt transport system, permease component
C7M23_03395	COG1122	ATPase activity
C7M23_03396	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M23_03397	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M23_03398	COG1404	Belongs to the peptidase S8 family
C7M23_03399	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M23_03400	COG0590	tRNA wobble adenosine to inosine editing
C7M23_03401	COG1764	response to oxidative stress
C7M23_03402	COG1846	Transcriptional regulator
C7M23_03403	COG1764	response to oxidative stress
C7M23_03404	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M23_03405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M23_03406	COG0788	formyltetrahydrofolate deformylase activity
C7M23_03407	COG2076	Multidrug Resistance protein
C7M23_03408	COG2076	Multidrug Resistance protein
C7M23_03409	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M23_03410	COG2318	DinB family
C7M23_03411	COG2323	membrane
C7M23_03413	COG1017	nitric oxide dioxygenase activity
C7M23_03413	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M23_03414	COG1607	acyl-coa hydrolase
C7M23_03415	COG1834	amidinotransferase
C7M23_03416	COG2706	6-phosphogluconolactonase activity
C7M23_03417	COG4608	Belongs to the ABC transporter superfamily
C7M23_03418	COG0791	NLP P60 protein
C7M23_03419	COG4948	Mandelate Racemase Muconate Lactonizing
C7M23_03420	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M23_03422	COG4166	transmembrane transport
C7M23_03423	COG0444	Belongs to the ABC transporter superfamily
C7M23_03424	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M23_03425	COG0601	transmembrane transport
C7M23_03426	COG2362	D-Aminopeptidase
C7M23_03427	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M23_03428	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M23_03430	COG0463	Glycosyl transferase, family 2
C7M23_03431	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M23_03432	COG0346	lactoylglutathione lyase activity
C7M23_03433	COG0531	amino acid
C7M23_03434	COG1392	Phosphate transport regulator
C7M23_03435	COG0306	phosphate transporter
C7M23_03438	COG3594	Acyltransferase
C7M23_03439	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_03439	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M23_03447	COG3778	Protein conserved in bacteria
C7M23_03448	COG3299	homolog of phage Mu protein gp47
C7M23_03449	COG3628	GPW Gp25 family protein
C7M23_03451	COG4193	domain, Protein
C7M23_03452	COG1652	LysM domain
C7M23_03453	COG3953	SLT domain
C7M23_03453	COG5412	phage tail tape measure protein
C7M23_03461	COG4653	Phage capsid family
C7M23_03462	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M23_03463	COG5518	Phage portal protein
C7M23_03464	COG1783	phage Terminase large subunit
C7M23_03465	COG5484	DNA packaging
C7M23_03465	COG3728	DNA packaging
C7M23_03466	COG1595	DNA-templated transcription, initiation
C7M23_03471	COG1484	DNA-dependent DNA replication
C7M23_03472	COG1522	sequence-specific DNA binding
C7M23_03474	COG1396	sequence-specific DNA binding
C7M23_03475	COG2856	Zn peptidase
C7M23_03476	COG3546	catalase activity
C7M23_03477	COG4195	phage-related replication protein
C7M23_03479	COG3409	Peptidoglycan-binding domain 1 protein
C7M23_03479	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M23_03479	COG1388	LysM domain
C7M23_03480	COG2350	Protein conserved in bacteria
C7M23_03482	COG0457	Tetratricopeptide repeat
C7M23_03483	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M23_03484	COG2318	DinB family
C7M23_03485	COG0730	response to heat
C7M23_03486	COG2721	sulfolactate sulfo-lyase activity
C7M23_03487	COG0246	Mannitol dehydrogenase
C7M23_03488	COG1609	Transcriptional regulator
C7M23_03489	COG2271	Major facilitator Superfamily
C7M23_03490	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_03491	COG1312	Catalyzes the dehydration of D-mannonate
C7M23_03492	COG1063	alcohol dehydrogenase
C7M23_03493	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M23_03494	COG2211	Major facilitator Superfamily
C7M23_03495	COG1904	glucuronate isomerase
C7M23_03496	COG1252	NADH dehydrogenase
C7M23_03498	COG4297	protein containing double-stranded beta helix domain
C7M23_03499	COG0697	spore germination
C7M23_03500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M23_03501	COG0390	transport system, permease component
C7M23_03502	COG1587	Uroporphyrinogen-III synthase
C7M23_03504	COG1819	glycosyl
C7M23_03505	COG2124	cytochrome p450
C7M23_03507	COG1051	belongs to the nudix hydrolase family
C7M23_03509	COG2427	Protein of unknown function (DUF1641)
C7M23_03510	COG3383	formate dehydrogenase (NAD+) activity
C7M23_03512	COG2205	protein histidine kinase activity
C7M23_03513	COG5504	Zn-dependent protease
C7M23_03516	COG0726	polysaccharide deacetylase
C7M23_03518	COG0109	protoheme IX farnesyltransferase activity
C7M23_03521	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M23_03523	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M23_03525	COG1482	cell wall glycoprotein biosynthetic process
C7M23_03526	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M23_03526	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M23_03526	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M23_03527	COG3711	transcriptional antiterminator
C7M23_03527	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M23_03529	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_03530	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M23_03531	COG5484	DNA packaging
C7M23_03537	COG5505	Protein of unknown function (DUF819)
C7M23_03538	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M23_03539	COG0626	cystathionine gamma-synthase activity
C7M23_03540	COG0626	cystathionine gamma-synthase activity
C7M23_03541	COG2382	esterase
C7M23_03542	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M23_03543	COG2153	protein acetylation
C7M23_03545	COG0210	DNA helicase
C7M23_03556	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M23_03557	COG0351	phosphomethylpyrimidine kinase
C7M23_03558	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M23_03559	COG2022	thiamine diphosphate biosynthetic process
C7M23_03560	COG2104	thiamine diphosphate biosynthetic process
C7M23_03561	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M23_03562	COG0352	thiamine-phosphate diphosphorylase activity
C7M23_03563	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7M23_03564	COG0475	glutathione-regulated potassium exporter activity
C7M23_03564	COG0569	domain protein
C7M23_03565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7M23_03566	COG0564	pseudouridine synthase activity
C7M23_03567	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M23_03568	COG2357	RelA SpoT domain protein
C7M23_03570	COG4116	CYTH
C7M23_03571	COG0741	lytic transglycosylase activity
C7M23_03572	COG2346	COG2346, Truncated hemoglobins
C7M23_03576	COG1164	Oligoendopeptidase f
C7M23_03577	COG4469	Competence protein
C7M23_03578	COG4862	establishment of competence for transformation
C7M23_03579	COG0861	Integral membrane protein TerC family
C7M23_03580	COG1393	Belongs to the ArsC family
C7M23_03581	COG0456	acetyltransferase
C7M23_03582	COG2814	Major facilitator Superfamily
C7M23_03583	COG4608	Belongs to the ABC transporter superfamily
C7M23_03584	COG0444	Belongs to the ABC transporter superfamily
C7M23_03585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M23_03586	COG0601	transmembrane transport
C7M23_03587	COG4166	transmembrane transport
C7M23_03588	COG0180	Tryptophanyl-tRNA synthetase
C7M23_03590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M23_03591	COG0601	transmembrane transport
C7M23_03593	COG4608	Belongs to the ABC transporter superfamily
C7M23_03594	COG0444	Belongs to the ABC transporter superfamily
C7M23_03595	COG5504	Zn-dependent protease
C7M23_03596	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M23_03597	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M23_03600	COG1744	ABC transporter substrate-binding protein PnrA-like
C7M23_03602	COG2267	carboxylic ester hydrolase activity
C7M23_03605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M23_03606	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M23_03607	COG0505	Belongs to the CarA family
C7M23_03608	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M23_03610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7M23_03611	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7M23_03612	COG2271	Major facilitator Superfamily
C7M23_03613	COG0277	FAD linked oxidase domain protein
C7M23_03615	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M23_03616	COG1073	alpha beta
C7M23_03617	COG0561	phosphatase activity
C7M23_03621	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M23_03622	COG1307	EDD domain protein, DegV family
C7M23_03623	COG3227	Zinc metalloprotease (Elastase)
C7M23_03626	COG1695	Transcriptional regulator
C7M23_03630	COG2996	Protein conserved in bacteria
C7M23_03631	COG1666	GTP binding
C7M23_03632	COG0646	methionine synthase
C7M23_03632	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M23_03633	COG2153	protein acetylation
C7M23_03634	COG0454	-acetyltransferase
C7M23_03635	COG2814	Major facilitator Superfamily
C7M23_03636	COG4948	Mandelate Racemase Muconate Lactonizing
C7M23_03637	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M23_03638	COG1809	phosphosulfolactate synthase activity
C7M23_03639	COG2045	Belongs to the ComB family
C7M23_03640	COG0175	sulfate reduction
C7M23_03641	COG2046	Belongs to the sulfate adenylyltransferase family
C7M23_03642	COG0529	Catalyzes the synthesis of activated sulfate
C7M23_03643	COG2267	carboxylic ester hydrolase activity
C7M23_03644	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M23_03645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M23_03646	COG1279	arginine transmembrane transporter activity
C7M23_03647	COG2318	DinB family
C7M23_03648	COG0673	inositol 2-dehydrogenase activity
C7M23_03649	COG1609	Transcriptional regulator
C7M23_03650	COG1917	Cupin 2, conserved barrel domain protein
C7M23_03650	COG2207	Transcriptional regulator
C7M23_03651	COG0534	Mate efflux family protein
C7M23_03652	COG1562	ergosterol biosynthetic process
C7M23_03653	COG2318	DinB family
C7M23_03654	COG0367	asparagine synthase
C7M23_03656	COG1404	Belongs to the peptidase S8 family
C7M23_03658	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7M23_03659	COG5337	Spore coat protein CotH
C7M23_03667	COG1403	HNH endonuclease
C7M23_03668	COG0419	ATPase involved in DNA repair
C7M23_03669	COG0420	3'-5' exonuclease activity
C7M23_03670	COG1074	ATP-dependent DNA helicase activity
C7M23_03671	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7M23_03672	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M23_03674	COG4533	DNA binding
C7M23_03675	COG0477	Major facilitator Superfamily
C7M23_03675	COG2814	Major facilitator Superfamily
C7M23_03676	COG3180	Ammonia monooxygenase
C7M23_03677	COG1609	Transcriptional regulator
C7M23_03678	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M23_03679	COG0561	phosphatase activity
C7M23_03680	COG0673	inositol 2-dehydrogenase activity
C7M23_03681	COG0738	Major facilitator superfamily
C7M23_03682	COG1846	Transcriptional regulator
C7M23_03683	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M23_03684	COG0681	Belongs to the peptidase S26 family
C7M23_03685	COG0398	Pfam SNARE associated Golgi protein
C7M23_03688	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M23_03690	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_03691	COG4903	ComK protein
C7M23_03693	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_03694	COG0723	plastoquinol--plastocyanin reductase activity
C7M23_03694	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M23_03695	COG0840	transmembrane signaling receptor activity
C7M23_03696	COG1268	BioY protein
C7M23_03697	COG0318	PFAM AMP-dependent synthetase and ligase
C7M23_03698	COG0183	Belongs to the thiolase family
C7M23_03699	COG0406	alpha-ribazole phosphatase activity
C7M23_03700	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M23_03701	COG0604	alcohol dehydrogenase
C7M23_03702	COG0456	acetyltransferase
C7M23_03703	COG1404	Belongs to the peptidase S8 family
C7M23_03704	COG0501	Belongs to the peptidase M48B family
C7M23_03706	COG0318	PFAM AMP-dependent synthetase and ligase
C7M23_03707	COG0702	epimerase
C7M23_03708	COG0095	Lipoate-protein ligase
C7M23_03709	COG1234	tRNA 3'-trailer cleavage
C7M23_03710	COG1301	dicarboxylic acid transport
C7M23_03711	COG4405	Protein conserved in bacteria
C7M23_03712	COG1363	Peptidase, m42
C7M23_03713	COG4377	Putative membrane peptidase family (DUF2324)
C7M23_03714	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M23_03715	COG1511	domain protein
C7M23_03716	COG1309	transcriptional regulator
C7M23_03719	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7M23_03720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M23_03721	COG2329	Antibiotic biosynthesis monooxygenase
C7M23_03723	COG3069	C4-dicarboxylate transmembrane transporter activity
C7M23_03724	COG1473	amidohydrolase
C7M23_03726	COG4473	ABC transporter
C7M23_03727	COG1131	(ABC) transporter
C7M23_03728	COG0537	adenosine 5'-monophosphoramidase activity
C7M23_03729	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M23_03731	COG4980	gas vesicle protein
C7M23_03732	COG1846	Transcriptional regulator
C7M23_03735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M23_03737	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7M23_03738	COG4717	serine-type aminopeptidase activity
C7M23_03739	COG0420	3'-5' exonuclease activity
C7M23_03740	COG1668	transmembrane transport
C7M23_03741	COG4152	abc transporter atp-binding protein
C7M23_03743	COG1024	Enoyl-CoA hydratase
C7M23_03745	COG0490	domain, Protein
C7M23_03746	COG0475	glutathione-regulated potassium exporter activity
C7M23_03747	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M23_03748	COG0561	phosphatase activity
C7M23_03749	COG4335	DNA alkylation repair
C7M23_03750	COG3679	Belongs to the UPF0342 family
C7M23_03751	COG4399	Belongs to the UPF0754 family
C7M23_03752	COG0189	ligase activity
C7M23_03753	COG0189	ligase activity
C7M23_03756	COG0702	epimerase
C7M23_03757	COG1132	(ABC) transporter
C7M23_03758	COG1132	(ABC) transporter
C7M23_03759	COG0589	response to stress
C7M23_03760	COG1757	Na H antiporter
C7M23_03761	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M23_03762	COG0726	polysaccharide deacetylase
C7M23_03763	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M23_03764	COG0668	transmembrane transport
C7M23_03766	COG0584	glycerophosphoryl diester phosphodiesterase
C7M23_03767	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M23_03768	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M23_03769	COG1253	flavin adenine dinucleotide binding
C7M23_03770	COG0436	Aminotransferase
C7M23_03771	COG0789	Transcriptional regulator
C7M23_03772	COG1253	flavin adenine dinucleotide binding
C7M23_03773	COG0204	Acyl-transferase
C7M23_03774	COG0667	Aldo Keto reductase
C7M23_03775	COG1595	DNA-templated transcription, initiation
C7M23_03778	COG0456	acetyltransferase
C7M23_03779	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M23_03780	COG0733	neurotransmitter:sodium symporter activity
C7M23_03781	COG0531	amino acid
C7M23_03782	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_03783	COG0372	Belongs to the citrate synthase family
C7M23_03784	COG0583	DNA-binding transcription factor activity
C7M23_03785	COG0791	NLP P60 protein
C7M23_03785	COG1388	LysM domain
C7M23_03786	COG1785	Belongs to the alkaline phosphatase family
C7M23_03787	COG2719	SpoVR family
C7M23_03788	COG0668	transmembrane transport
C7M23_03789	COG1959	2 iron, 2 sulfur cluster binding
C7M23_03790	COG1388	LysM domain
C7M23_03790	COG0791	NLP P60 protein
C7M23_03793	COG0431	NADPH-dependent FMN reductase
C7M23_03794	COG2197	response regulator
C7M23_03795	COG4585	Histidine kinase
C7M23_03795	COG2203	Gaf domain
C7M23_03796	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M23_03797	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7M23_03798	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M23_03799	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M23_03800	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7M23_03801	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M23_03802	COG3153	acetyltransferase
C7M23_03802	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M23_03803	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M23_03804	COG0517	IMP dehydrogenase activity
C7M23_03806	COG0564	pseudouridine synthase activity
C7M23_03807	COG3764	Sortase (surface protein transpeptidase)
C7M23_03808	COG0737	Belongs to the 5'-nucleotidase family
C7M23_03808	COG1525	nuclease
C7M23_03808	COG4085	toxin activity
C7M23_03809	COG5577	PFAM Coat F domain
C7M23_03813	COG1823	symporter activity
C7M23_03814	COG3706	GGDEF domain
C7M23_03815	COG1464	Belongs to the NlpA lipoprotein family
C7M23_03816	COG1278	Cold shock
C7M23_03817	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M23_03818	COG1131	(ABC) transporter
C7M23_03819	COG1131	(ABC) transporter
C7M23_03820	COG1725	Transcriptional regulator
C7M23_03823	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M23_03824	COG2814	Major facilitator Superfamily
C7M23_03825	COG1566	PFAM secretion protein HlyD family protein
C7M23_03826	COG1846	Transcriptional regulator
C7M23_03827	COG2718	Belongs to the UPF0229 family
C7M23_03828	COG2766	serine protein kinase
C7M23_03829	COG1664	Polymer-forming cytoskeletal
C7M23_03830	COG1664	Polymer-forming cytoskeletal
C7M23_03831	COG0789	Transcriptional regulator
C7M23_03832	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M23_03834	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7M23_03835	COG3382	B3 4 domain protein
C7M23_03837	COG1476	TRANSCRIPTIONal
C7M23_03839	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M23_03841	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M23_03842	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M23_03843	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M23_03844	COG1116	anion transmembrane transporter activity
C7M23_03845	COG0753	catalase activity
C7M23_03847	COG0277	FAD linked oxidase domain protein
C7M23_03848	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7M23_03849	COG3340	Belongs to the peptidase S51 family
C7M23_03851	COG4326	sporulation control protein
C7M23_03873	COG0735	belongs to the Fur family
C7M23_03874	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7M23_03875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M23_03876	COG4129	membrane
C7M23_03877	COG1132	(ABC) transporter
C7M23_03878	COG3557	Belongs to the UPF0374 family
C7M23_03881	COG1028	Short-chain dehydrogenase reductase Sdr
C7M23_03883	COG1194	a g-specific adenine glycosylase
C7M23_03884	COG1988	membrane-bound metal-dependent
C7M23_03885	COG4485	Bacterial membrane protein, YfhO
C7M23_03886	COG0463	Glycosyl transferase, family 2
C7M23_03887	COG0596	Alpha beta hydrolase
C7M23_03888	COG5658	integral membrane protein
C7M23_03889	COG3103	Sh3 type 3 domain protein
C7M23_03892	COG2814	Major facilitator Superfamily
C7M23_03895	COG2137	regulation of response to DNA damage stimulus
C7M23_03896	COG1090	epimerase
C7M23_03899	COG0778	Nitroreductase
C7M23_03900	COG0384	phenazine biosynthesis protein PhzF
C7M23_03901	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M23_03902	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M23_03903	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M23_03904	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7M23_03904	COG0392	lysyltransferase activity
C7M23_03905	COG1846	Transcriptional regulator
C7M23_03906	COG2814	Major facilitator Superfamily
C7M23_03907	COG2318	DinB family
C7M23_03908	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7M23_03909	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M23_03910	COG1695	Transcriptional regulator
C7M23_03911	COG0842	Transport permease protein
C7M23_03912	COG0842	Transport permease protein
C7M23_03912	COG1511	domain protein
C7M23_03913	COG1131	(ABC) transporter
C7M23_03914	COG2197	response regulator
C7M23_03915	COG4585	Histidine kinase
C7M23_03917	COG2514	catechol 2,3-dioxygenase activity
C7M23_03918	COG2259	Doxx family
C7M23_03919	COG1132	(ABC) transporter
C7M23_03920	COG1132	(ABC) transporter
C7M23_03921	COG1263	PTS System
C7M23_03921	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M23_03922	COG1737	Transcriptional regulator
C7M23_03923	COG1486	melibiose metabolic process
C7M23_03924	COG4842	Belongs to the WXG100 family
C7M23_03929	COG1742	UPF0060 membrane protein
C7M23_03931	COG3284	Transcriptional regulator
C7M23_03932	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M23_03933	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M23_03934	COG0022	dehydrogenase e1 component
C7M23_03935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M23_03938	COG4637	Psort location Cytoplasmic, score
C7M23_03939	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M23_03941	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M23_03942	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M23_03943	COG0598	Magnesium transport protein CorA
C7M23_03944	COG2084	Dehydrogenase
C7M23_03945	COG0726	polysaccharide deacetylase
C7M23_03947	COG0535	radical SAM domain protein
C7M23_03948	COG0668	transmembrane transport
C7M23_03950	COG0387	Pfam Sodium calcium exchanger
C7M23_03951	COG0477	Major facilitator Superfamily
C7M23_03952	COG1295	ribonuclease BN
C7M23_03953	COG4980	gas vesicle protein
C7M23_03954	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M23_03955	COG4840	Belongs to the UPF0435 family
C7M23_03956	COG2814	Major facilitator Superfamily
C7M23_03957	COG0693	protein deglycase activity
C7M23_03958	COG0737	Belongs to the 5'-nucleotidase family
C7M23_03959	COG0778	Nitroreductase
C7M23_03960	COG2188	Transcriptional regulator
C7M23_03961	COG0366	Alpha amylase catalytic
C7M23_03962	COG1263	PTS System
C7M23_03962	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M23_03963	COG0697	spore germination
C7M23_03966	COG0531	amino acid
C7M23_03967	COG1115	amino acid carrier protein
C7M23_03969	COG1368	sulfuric ester hydrolase activity
C7M23_03970	COG1263	PTS System
C7M23_03970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M23_03971	COG0024	Methionine aminopeptidase
C7M23_03975	COG2258	MOSC domain
C7M23_03976	COG1254	Belongs to the acylphosphatase family
C7M23_03977	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C7M23_03978	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M23_03979	COG2851	Citrate transporter
C7M23_03980	COG3181	Tripartite tricarboxylate transporter family receptor
C7M23_03981	COG4565	transcriptional regulatory protein
C7M23_03982	COG3290	protein histidine kinase activity
C7M23_03983	COG0471	metal ion transport
C7M23_03984	COG3866	Pectate lyase
C7M23_03987	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M23_03988	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M23_03989	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M23_03990	COG1120	ATPase activity
C7M23_03991	COG2130	NADP-dependent
C7M23_03992	COG0456	acetyltransferase
C7M23_03993	COG0513	Belongs to the DEAD box helicase family
C7M23_03994	COG0488	(ABC) transporter
C7M23_03995	COG2814	Major facilitator Superfamily
C7M23_03996	COG0789	Transcriptional regulator
C7M23_03998	COG0488	(ABC) transporter
C7M23_03999	COG0840	transmembrane signaling receptor activity
C7M23_04000	COG1012	belongs to the aldehyde dehydrogenase family
C7M23_04001	COG0531	amino acid
C7M23_04002	COG1011	Hydrolase
C7M23_04003	COG2223	nitrite transmembrane transporter activity
C7M23_04004	COG1442	glycosyl transferase family 8
C7M23_04005	COG1216	Glycosyl transferase, family 2
C7M23_04006	COG1442	glycosyl transferase family 8
C7M23_04007	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M23_04008	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7M23_04009	COG1368	sulfuric ester hydrolase activity
C7M23_04010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M23_04010	COG2124	cytochrome p450
C7M23_04012	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M23_04013	COG1846	Transcriptional regulator
C7M23_04014	COG0697	spore germination
C7M23_04015	COG0670	Belongs to the BI1 family
C7M23_04016	COG5583	Uncharacterized small protein (DUF2292)
C7M23_04019	COG0346	lactoylglutathione lyase activity
C7M23_04020	COG2323	membrane
C7M23_04021	COG1486	melibiose metabolic process
C7M23_04022	COG0395	ABC-type sugar transport system, permease component
C7M23_04023	COG4209	transmembrane transport
C7M23_04024	COG1653	transport
C7M23_04026	COG1874	Beta-galactosidase
C7M23_04027	COG2755	lipolytic protein G-D-S-L family
C7M23_04028	COG3401	FG-GAP repeat protein
C7M23_04029	COG3401	FG-GAP repeat protein
C7M23_04030	COG5578	integral membrane protein
C7M23_04032	COG2755	lipolytic protein G-D-S-L family
C7M23_04033	COG2207	Transcriptional regulator
C7M23_04034	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M23_04035	COG0395	ABC-type sugar transport system, permease component
C7M23_04036	COG1175	transmembrane transport
C7M23_04037	COG1653	transport
C7M23_04038	COG2207	Transcriptional regulator
C7M23_04038	COG4753	response regulator
C7M23_04039	COG2972	Histidine kinase
C7M23_04040	COG5578	integral membrane protein
C7M23_04042	COG0454	-acetyltransferase
C7M23_04043	COG3546	catalase activity
C7M23_04046	COG0702	epimerase
C7M23_04047	COG3631	Ketosteroid isomerase-related protein
C7M23_04048	COG1309	transcriptional regulator
C7M23_04050	COG0217	transcriptional regulatory protein
C7M23_04052	COG0457	Tetratricopeptide repeat
C7M23_04053	COG2323	membrane
C7M23_04055	COG3586	endonuclease activity
C7M23_04057	COG5444	nuclease activity
C7M23_04060	COG0457	Tetratricopeptide repeat
C7M23_04061	COG0457	Tetratricopeptide repeat
C7M23_04064	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C7M23_04065	COG0732	type I restriction modification DNA specificity domain
C7M23_04066	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C7M23_04068	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M23_04069	COG1597	lipid kinase activity
C7M23_04070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7M23_04071	COG1309	transcriptional regulator
C7M23_04072	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M23_04073	COG0154	amidase activity
C7M23_04074	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M23_04075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M23_04076	COG1285	pathogenesis
C7M23_04077	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M23_04078	COG4851	CamS sex pheromone cAM373 precursor
C7M23_04079	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7M23_04080	COG0210	DNA helicase
C7M23_04081	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C7M23_04083	COG0069	glutamate synthase activity
C7M23_04084	COG4496	protein, YerC YecD
C7M23_04085	COG1470	cell adhesion involved in biofilm formation
C7M23_04086	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M23_04088	COG0531	amino acid
C7M23_04089	COG1522	sequence-specific DNA binding
C7M23_04090	COG0151	Belongs to the GarS family
C7M23_04091	COG0138	bifunctional purine biosynthesis protein purh
C7M23_04092	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M23_04093	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7M23_04094	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7M23_04095	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M23_04096	COG0047	phosphoribosylformylglycinamidine synthase activity
C7M23_04097	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M23_04098	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M23_04099	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M23_04100	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M23_04101	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7M23_04103	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C7M23_04105	COG3064	Membrane
C7M23_04106	COG2252	PERMEase
C7M23_04110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7M23_04110	COG0519	Catalyzes the synthesis of GMP from XMP
C7M23_04111	COG1305	Transglutaminase-like
C7M23_04112	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C7M23_04113	COG0714	Associated with various cellular activities
C7M23_04114	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M23_04115	COG1113	amino acid transport
C7M23_04116	COG2132	Multicopper oxidase
C7M23_04118	COG2267	carboxylic ester hydrolase activity
C7M23_04121	COG0823	Involved in the tonB-independent uptake of proteins
C7M23_04122	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7M23_04123	COG1063	alcohol dehydrogenase
C7M23_04124	COG2814	Major facilitator Superfamily
C7M23_04126	COG4260	virion core protein, lumpy skin disease virus
C7M23_04127	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7M23_04128	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M23_04129	COG1842	Phage shock protein A