locus-tag	class	description
C7M27_00002	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M27_00003	COG0583	DNA-binding transcription factor activity
C7M27_00004	COG0028	Belongs to the TPP enzyme family
C7M27_00005	COG3527	Alpha-acetolactate decarboxylase
C7M27_00006	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M27_00008	COG3103	Sh3 type 3 domain protein
C7M27_00009	COG1879	ABC-type sugar transport system periplasmic component
C7M27_00010	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7M27_00011	COG1129	ABC transporter
C7M27_00012	COG1869	D-ribose catabolic process
C7M27_00013	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M27_00014	COG1609	Transcriptional regulator
C7M27_00015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M27_00017	COG2843	Capsule synthesis protein
C7M27_00019	COG0791	NLP P60 protein
C7M27_00020	COG0561	phosphatase activity
C7M27_00021	COG1316	TRANSCRIPTIONal
C7M27_00022	COG2814	Major facilitator Superfamily
C7M27_00024	COG0814	amino acid
C7M27_00025	COG0697	spore germination
C7M27_00026	COG1482	cell wall glycoprotein biosynthetic process
C7M27_00027	COG4193	domain, Protein
C7M27_00032	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C7M27_00033	COG4193	domain, Protein
C7M27_00042	COG1682	transport, permease protein
C7M27_00043	COG1134	teichoic acid transport
C7M27_00044	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M27_00047	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M27_00048	COG1316	TRANSCRIPTIONal
C7M27_00050	COG2385	sporulation resulting in formation of a cellular spore
C7M27_00050	COG2247	cell wall binding repeat
C7M27_00051	COG2247	cell wall binding repeat
C7M27_00051	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M27_00053	COG2244	polysaccharide biosynthetic process
C7M27_00054	COG0297	glycogen (starch) synthase activity
C7M27_00054	COG0438	transferase activity, transferring glycosyl groups
C7M27_00055	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M27_00056	COG3307	-O-antigen
C7M27_00057	COG3206	protein involved in exopolysaccharide biosynthesis
C7M27_00058	COG1215	transferase activity, transferring glycosyl groups
C7M27_00059	COG0438	transferase activity, transferring glycosyl groups
C7M27_00060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M27_00061	COG1316	TRANSCRIPTIONal
C7M27_00062	COG1739	Uncharacterized protein family UPF0029
C7M27_00063	COG4585	Histidine kinase
C7M27_00064	COG2197	response regulator
C7M27_00065	COG1307	EDD domain protein, DegV family
C7M27_00066	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M27_00068	COG1040	competence protein
C7M27_00070	COG2747	anti-sigma28 factor FlgM
C7M27_00071	COG3418	PFAM FlgN family protein
C7M27_00072	COG1256	bacterial-type flagellum assembly
C7M27_00072	COG4786	Flagellar basal body rod
C7M27_00073	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M27_00075	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C7M27_00076	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C7M27_00077	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M27_00078	COG1334	flagellar protein FlaG
C7M27_00079	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7M27_00080	COG1516	flagellar protein fliS
C7M27_00083	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7M27_00084	COG0653	protein targeting
C7M27_00085	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C7M27_00086	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M27_00087	COG2010	Cytochrome c
C7M27_00088	COG2884	Cell division ATP-binding protein ftsE
C7M27_00089	COG2177	Part of the ABC transporter FtsEX involved in
C7M27_00090	COG3409	Peptidoglycan-binding domain 1 protein
C7M27_00090	COG0793	Belongs to the peptidase S41A family
C7M27_00092	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M27_00093	COG2814	Major facilitator Superfamily
C7M27_00094	COG1309	transcriptional regulator
C7M27_00095	COG3848	Pyruvate phosphate dikinase
C7M27_00095	COG0574	Belongs to the PEP-utilizing enzyme family
C7M27_00096	COG4897	Protein conserved in bacteria
C7M27_00097	COG0556	nucleotide-excision repair
C7M27_00098	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M27_00099	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M27_00102	COG3595	metallopeptidase activity
C7M27_00103	COG1983	PspC domain protein
C7M27_00104	COG1950	PFAM Membrane protein of
C7M27_00105	COG2814	Major facilitator Superfamily
C7M27_00106	COG1846	Transcriptional regulator
C7M27_00108	COG2124	cytochrome p450
C7M27_00109	COG1846	Transcriptional regulator
C7M27_00110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M27_00111	COG2188	Transcriptional regulator
C7M27_00112	COG0363	glucosamine-6-phosphate deaminase activity
C7M27_00113	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7M27_00114	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7M27_00115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7M27_00116	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7M27_00117	COG0546	phosphoglycolate phosphatase activity
C7M27_00118	COG0110	maltose O-acetyltransferase activity
C7M27_00119	COG5297	Belongs to the glycosyl hydrolase family 6
C7M27_00120	COG4990	cell redox homeostasis
C7M27_00121	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7M27_00122	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7M27_00123	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M27_00124	COG0131	Imidazoleglycerol-phosphate dehydratase
C7M27_00125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7M27_00126	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7M27_00127	COG0107	imidazoleglycerol-phosphate synthase activity
C7M27_00128	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M27_00128	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M27_00132	COG1132	(ABC) transporter
C7M27_00133	COG0457	Tetratricopeptide repeat
C7M27_00134	COG3883	PFAM NLP P60 protein
C7M27_00134	COG0791	NLP P60 protein
C7M27_00135	COG0492	ferredoxin-NADP+ reductase activity
C7M27_00136	COG1051	belongs to the nudix hydrolase family
C7M27_00137	COG1660	Displays ATPase and GTPase activities
C7M27_00138	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M27_00139	COG1481	regulation of sporulation
C7M27_00140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M27_00141	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7M27_00143	COG0745	RESPONSE REGULATOR receiver
C7M27_00144	COG5002	protein histidine kinase activity
C7M27_00145	COG1136	(ABC) transporter
C7M27_00146	COG0577	efflux transmembrane transporter activity
C7M27_00147	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M27_00148	COG0288	reversible hydration of carbon dioxide
C7M27_00149	COG0659	secondary active sulfate transmembrane transporter activity
C7M27_00150	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M27_00151	COG1611	Belongs to the LOG family
C7M27_00152	COG1609	Transcriptional regulator
C7M27_00153	COG0366	Alpha amylase catalytic
C7M27_00154	COG2182	Extracellular solute-binding protein
C7M27_00155	COG1175	transmembrane transport
C7M27_00156	COG3833	ABC-type maltose transport systems, permease component
C7M27_00157	COG5521	maltodextrose utilization protein MalA
C7M27_00158	COG1554	hydrolase, family 65, central catalytic
C7M27_00159	COG0366	Alpha amylase catalytic
C7M27_00160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M27_00161	COG0740	serine-type endopeptidase activity
C7M27_00164	COG2076	Multidrug Resistance protein
C7M27_00165	COG2076	Multidrug Resistance protein
C7M27_00166	COG1309	transcriptional regulator
C7M27_00167	COG0531	amino acid
C7M27_00168	COG1621	beta-fructofuranosidase activity
C7M27_00169	COG1621	beta-fructofuranosidase activity
C7M27_00170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M27_00171	COG1794	racemase activity, acting on amino acids and derivatives
C7M27_00173	COG3479	Phenolic acid decarboxylase
C7M27_00175	COG2272	Belongs to the type-B carboxylesterase lipase family
C7M27_00176	COG1396	sequence-specific DNA binding
C7M27_00177	COG3944	biosynthesis protein
C7M27_00178	COG0489	protein tyrosine kinase activity
C7M27_00179	COG1086	Polysaccharide biosynthesis protein
C7M27_00180	COG0438	transferase activity, transferring glycosyl groups
C7M27_00181	COG1215	transferase activity, transferring glycosyl groups
C7M27_00182	COG0438	transferase activity, transferring glycosyl groups
C7M27_00184	COG1216	Glycosyl transferase, family 2
C7M27_00185	COG5039	Polysaccharide pyruvyl transferase
C7M27_00186	COG1216	Glycosyl transferase, family 2
C7M27_00187	COG2244	polysaccharide biosynthetic process
C7M27_00188	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M27_00189	COG0110	maltose O-acetyltransferase activity
C7M27_00190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M27_00191	COG5039	Polysaccharide pyruvyl transferase
C7M27_00193	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M27_00194	COG1620	l-lactate permease
C7M27_00195	COG2186	Transcriptional regulator
C7M27_00196	COG1609	Transcriptional regulator
C7M27_00197	COG2182	Extracellular solute-binding protein
C7M27_00198	COG1175	transmembrane transport
C7M27_00199	COG3833	ABC-type maltose transport systems, permease component
C7M27_00200	COG1874	Beta-galactosidase
C7M27_00201	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C7M27_00202	COG2208	phosphoserine phosphatase activity
C7M27_00203	COG0596	Alpha beta hydrolase
C7M27_00205	COG1131	(ABC) transporter
C7M27_00206	COG0842	Transport permease protein
C7M27_00207	COG4585	Histidine kinase
C7M27_00208	COG2197	response regulator
C7M27_00211	COG0247	lactate metabolic process
C7M27_00212	COG1139	Iron-sulfur cluster binding protein
C7M27_00213	COG1556	Lactate utilization protein
C7M27_00214	COG3858	chitin binding
C7M27_00215	COG1113	amino acid transport
C7M27_00216	COG0697	spore germination
C7M27_00217	COG0583	DNA-binding transcription factor activity
C7M27_00218	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M27_00219	COG1609	Transcriptional regulator
C7M27_00220	COG2814	Major facilitator Superfamily
C7M27_00221	COG2390	Transcriptional regulator
C7M27_00222	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M27_00223	COG0126	phosphoglycerate kinase activity
C7M27_00224	COG0149	triose-phosphate isomerase activity
C7M27_00225	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7M27_00226	COG0148	phosphopyruvate hydratase activity
C7M27_00227	COG0456	acetyltransferase
C7M27_00228	COG4640	response to antibiotic
C7M27_00229	COG3064	Membrane
C7M27_00231	COG2095	MarC family integral membrane protein
C7M27_00232	COG1510	regulation of RNA biosynthetic process
C7M27_00233	COG1125	glycine betaine transport
C7M27_00233	COG0517	IMP dehydrogenase activity
C7M27_00234	COG1174	glycine betaine transport
C7M27_00235	COG1732	Glycine betaine
C7M27_00236	COG1174	glycine betaine transport
C7M27_00237	COG1510	regulation of RNA biosynthetic process
C7M27_00238	COG1125	glycine betaine transport
C7M27_00238	COG0517	IMP dehydrogenase activity
C7M27_00239	COG1174	glycine betaine transport
C7M27_00240	COG1732	Glycine betaine
C7M27_00241	COG1174	glycine betaine transport
C7M27_00247	COG1131	(ABC) transporter
C7M27_00252	COG0840	transmembrane signaling receptor activity
C7M27_00253	COG1733	regulation of RNA biosynthetic process
C7M27_00254	COG1396	sequence-specific DNA binding
C7M27_00255	COG1396	sequence-specific DNA binding
C7M27_00256	COG1476	TRANSCRIPTIONal
C7M27_00257	COG0596	Alpha beta hydrolase
C7M27_00258	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M27_00259	COG1647	Serine aminopeptidase, S33
C7M27_00260	COG0557	exoribonuclease II activity
C7M27_00261	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7M27_00263	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_00264	COG1309	transcriptional regulator
C7M27_00265	COG2076	Multidrug Resistance protein
C7M27_00267	COG1289	transmembrane transporter activity
C7M27_00268	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M27_00269	COG0673	inositol 2-dehydrogenase activity
C7M27_00270	COG1937	Protein conserved in bacteria
C7M27_00271	COG2608	mercury ion transmembrane transporter activity
C7M27_00272	COG2217	Heavy metal translocating P-type atpase
C7M27_00273	COG2217	Heavy metal translocating P-type atpase
C7M27_00274	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7M27_00275	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M27_00276	COG2860	membrane
C7M27_00278	COG3973	AAA domain
C7M27_00279	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M27_00280	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M27_00281	COG0025	NhaP-type Na H and K H
C7M27_00283	COG0656	L-ascorbic acid biosynthetic process
C7M27_00284	COG4149	molybdate abc transporter
C7M27_00285	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7M27_00286	COG1910	domain protein
C7M27_00287	COG1368	sulfuric ester hydrolase activity
C7M27_00288	COG1988	membrane-bound metal-dependent
C7M27_00290	COG0531	amino acid
C7M27_00292	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M27_00293	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M27_00294	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M27_00295	COG1120	ATPase activity
C7M27_00296	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M27_00297	COG1136	(ABC) transporter
C7M27_00298	COG0577	efflux transmembrane transporter activity
C7M27_00300	COG2140	Oxalate decarboxylase
C7M27_00302	COG1191	sigma factor activity
C7M27_00304	COG0745	RESPONSE REGULATOR receiver
C7M27_00305	COG2205	protein histidine kinase activity
C7M27_00306	COG3386	PFAM SMP-30 Gluconolaconase
C7M27_00307	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_00308	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M27_00309	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M27_00310	COG1120	ATPase activity
C7M27_00311	COG2096	Adenosyltransferase
C7M27_00312	COG2814	Major facilitator Superfamily
C7M27_00313	COG4758	membrane
C7M27_00314	COG1842	Phage shock protein A
C7M27_00315	COG3595	metallopeptidase activity
C7M27_00316	COG4758	membrane
C7M27_00317	COG4585	Histidine kinase
C7M27_00318	COG2197	response regulator
C7M27_00320	COG0814	amino acid
C7M27_00321	COG0697	spore germination
C7M27_00323	COG0114	fumarate hydratase activity
C7M27_00324	COG1309	transcriptional regulator
C7M27_00325	COG2770	Histidine kinase
C7M27_00325	COG2205	protein histidine kinase activity
C7M27_00326	COG0745	RESPONSE REGULATOR receiver
C7M27_00327	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M27_00328	COG0783	Belongs to the Dps family
C7M27_00329	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_00332	COG1120	ATPase activity
C7M27_00334	COG0583	DNA-binding transcription factor activity
C7M27_00335	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_00336	COG1942	4-Oxalocrotonate Tautomerase
C7M27_00337	COG0477	Major facilitator Superfamily
C7M27_00338	COG1846	Transcriptional regulator
C7M27_00339	COG5577	PFAM Coat F domain
C7M27_00341	COG0506	proline dehydrogenase activity
C7M27_00343	COG1024	Enoyl-CoA hydratase
C7M27_00343	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M27_00344	COG0183	Belongs to the thiolase family
C7M27_00345	COG1960	acyl-CoA dehydrogenase activity
C7M27_00346	COG1393	Belongs to the ArsC family
C7M27_00347	COG0509	glycine decarboxylation via glycine cleavage system
C7M27_00349	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M27_00350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_00352	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M27_00353	COG2011	ABC-type metal ion transport system permease component
C7M27_00354	COG1464	Belongs to the NlpA lipoprotein family
C7M27_00355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M27_00356	COG0396	ATPase activity
C7M27_00357	COG0719	Fe-S assembly protein
C7M27_00358	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M27_00359	COG0822	iron-sulfur transferase activity
C7M27_00360	COG0719	Fe-S assembly protein
C7M27_00361	COG0640	Transcriptional regulator
C7M27_00362	COG0346	lactoylglutathione lyase activity
C7M27_00365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M27_00366	COG0322	excinuclease ABC activity
C7M27_00367	COG2222	sugar isomerase
C7M27_00368	COG1653	transport
C7M27_00369	COG1175	transmembrane transport
C7M27_00370	COG0395	ABC-type sugar transport system, permease component
C7M27_00371	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M27_00372	COG2188	Transcriptional regulator
C7M27_00373	COG3842	ATPase activity
C7M27_00374	COG2356	endonuclease I
C7M27_00375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M27_00376	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M27_00377	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7M27_00378	COG2068	MobA-Related Protein
C7M27_00379	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C7M27_00380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7M27_00381	COG2080	2 iron, 2 sulfur cluster binding
C7M27_00383	COG2351	hydroxyisourate hydrolase activity
C7M27_00384	COG3648	Uricase
C7M27_00384	COG3195	allantoin biosynthetic process
C7M27_00385	COG2233	PERMEase
C7M27_00386	COG2233	PERMEase
C7M27_00387	COG2508	Transcriptional regulator
C7M27_00388	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M27_00390	COG1801	Protein of unknown function DUF72
C7M27_00391	COG0730	response to heat
C7M27_00392	COG0737	Belongs to the 5'-nucleotidase family
C7M27_00393	COG3377	Domain of unknown function (DUF1805)
C7M27_00395	COG0739	heme binding
C7M27_00396	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7M27_00398	COG4470	Protein conserved in bacteria
C7M27_00399	COG2445	Protein of unknown function DUF86
C7M27_00400	COG0647	UMP catabolic process
C7M27_00401	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M27_00402	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M27_00403	COG0460	homoserine dehydrogenase
C7M27_00404	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7M27_00405	COG0083	homoserine kinase activity
C7M27_00406	COG0823	Involved in the tonB-independent uptake of proteins
C7M27_00406	COG1506	peptidase
C7M27_00406	COG4946	Tricorn protease homolog
C7M27_00407	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7M27_00408	COG4837	Protein of unknown function (DUF1462)
C7M27_00409	COG1252	NADH dehydrogenase
C7M27_00410	COG4844	belongs to the
C7M27_00411	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M27_00412	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7M27_00413	COG0316	Belongs to the HesB IscA family
C7M27_00414	COG0456	acetyltransferase
C7M27_00415	COG2808	Putative FMN-binding domain
C7M27_00416	COG0516	GMP reductase activity
C7M27_00418	COG0492	ferredoxin-NADP+ reductase activity
C7M27_00419	COG1252	NADH dehydrogenase
C7M27_00421	COG3584	3D domain protein
C7M27_00422	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7M27_00423	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7M27_00424	COG2056	Na+-H+ antiporter family
C7M27_00425	COG1268	BioY protein
C7M27_00426	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M27_00427	COG2819	hydrolase of the alpha beta superfamily
C7M27_00428	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_00429	COG1169	isochorismate synthase
C7M27_00430	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7M27_00431	COG1535	isochorismatase
C7M27_00431	COG3433	isochorismatase activity
C7M27_00432	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_00433	COG3251	PFAM MbtH domain protein
C7M27_00434	COG5634	Uncharacterized conserved protein (DUF2278)
C7M27_00435	COG0686	Belongs to the AlaDH PNT family
C7M27_00436	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M27_00436	COG2508	Transcriptional regulator
C7M27_00437	COG4842	Belongs to the WXG100 family
C7M27_00438	COG5417	Belongs to the EsaB family
C7M27_00439	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M27_00440	COG1674	ftsk spoiiie
C7M27_00440	COG0433	COG0433 Predicted ATPase
C7M27_00441	COG1511	domain protein
C7M27_00443	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_00444	COG1418	mRNA catabolic process
C7M27_00447	COG0628	permease
C7M27_00450	COG5506	Protein of unknown function (DUF1694)
C7M27_00451	COG1335	isochorismatase
C7M27_00452	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M27_00453	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7M27_00456	COG0142	geranyltranstransferase activity
C7M27_00458	COG4585	Histidine kinase
C7M27_00459	COG2197	response regulator
C7M27_00460	COG2050	protein possibly involved in aromatic compounds catabolism
C7M27_00461	COG1320	monovalent cation:proton antiporter activity
C7M27_00462	COG2212	antiporter activity
C7M27_00463	COG1863	multisubunit Na H antiporter MnhE subunit
C7M27_00464	COG0651	ATP synthesis coupled electron transport
C7M27_00465	COG1006	Multisubunit Na H antiporter MnhC subunit
C7M27_00466	COG2111	Na H antiporter
C7M27_00467	COG2111	Na H antiporter
C7M27_00467	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M27_00469	COG3493	citrate carrier protein
C7M27_00474	COG4565	transcriptional regulatory protein
C7M27_00475	COG3290	protein histidine kinase activity
C7M27_00477	COG3011	Protein conserved in bacteria
C7M27_00478	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M27_00479	COG2814	Major facilitator Superfamily
C7M27_00481	COG5018	Exonuclease
C7M27_00483	COG2205	protein histidine kinase activity
C7M27_00484	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M27_00486	COG2267	carboxylic ester hydrolase activity
C7M27_00487	COG1522	sequence-specific DNA binding
C7M27_00488	COG0436	Aminotransferase
C7M27_00489	COG1098	S1 RNA binding domain
C7M27_00490	COG2155	Conserved Protein
C7M27_00491	COG1979	alcohol dehydrogenase
C7M27_00492	COG1979	alcohol dehydrogenase
C7M27_00493	COG0166	Belongs to the GPI family
C7M27_00496	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M27_00499	COG2738	Putative neutral zinc metallopeptidase
C7M27_00500	COG1253	flavin adenine dinucleotide binding
C7M27_00501	COG0366	Alpha amylase catalytic
C7M27_00502	COG0432	Pfam Uncharacterised protein family UPF0047
C7M27_00505	COG0840	transmembrane signaling receptor activity
C7M27_00506	COG0840	transmembrane signaling receptor activity
C7M27_00507	COG0840	transmembrane signaling receptor activity
C7M27_00508	COG0840	transmembrane signaling receptor activity
C7M27_00509	COG3347	Dehydrogenase
C7M27_00509	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_00510	COG1349	DNA-binding transcription factor activity
C7M27_00511	COG1070	Carbohydrate kinase
C7M27_00512	COG3254	rhamnose metabolic process
C7M27_00513	COG4806	L-rhamnose isomerase
C7M27_00514	COG0673	inositol 2-dehydrogenase activity
C7M27_00515	COG0628	permease
C7M27_00516	COG1968	undecaprenyl-diphosphatase activity
C7M27_00518	COG5553	Cysteine dioxygenase type I
C7M27_00519	COG0477	Major facilitator Superfamily
C7M27_00520	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M27_00521	COG4682	membrane
C7M27_00522	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M27_00523	COG0569	domain protein
C7M27_00525	COG1510	regulation of RNA biosynthetic process
C7M27_00526	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_00527	COG1454	alcohol dehydrogenase
C7M27_00529	COG2318	DinB family
C7M27_00530	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7M27_00531	COG2268	Band 7 protein
C7M27_00532	COG1247	-acetyltransferase
C7M27_00533	COG3859	Proton-coupled thiamine transporter YuaJ
C7M27_00558	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7M27_00559	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M27_00560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M27_00561	COG0297	glycogen (starch) synthase activity
C7M27_00562	COG0058	SHG alpha-glucan phosphorylase activity
C7M27_00563	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M27_00564	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M27_00565	COG0438	transferase activity, transferring glycosyl groups
C7M27_00566	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M27_00568	COG0438	transferase activity, transferring glycosyl groups
C7M27_00569	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M27_00570	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M27_00571	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M27_00572	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M27_00573	COG1169	isochorismate synthase
C7M27_00574	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7M27_00575	COG0596	Alpha beta hydrolase
C7M27_00576	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7M27_00577	COG0318	PFAM AMP-dependent synthetase and ligase
C7M27_00578	COG4948	Mandelate Racemase Muconate Lactonizing
C7M27_00579	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M27_00580	COG1121	(ABC) transporter
C7M27_00581	COG1321	iron dependent repressor
C7M27_00581	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M27_00582	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M27_00584	COG1294	oxidase, subunit
C7M27_00585	COG1271	oxidase subunit
C7M27_00586	COG0254	rRNA binding
C7M27_00587	COG0288	reversible hydration of carbon dioxide
C7M27_00588	COG1854	S-ribosylhomocysteine lyase activity
C7M27_00591	COG0783	Belongs to the Dps family
C7M27_00592	COG4824	toxin secretion phage lysis holin
C7M27_00593	COG0494	nUDIX hydrolase
C7M27_00594	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M27_00595	COG1116	anion transmembrane transporter activity
C7M27_00596	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M27_00597	COG1506	peptidase
C7M27_00599	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7M27_00600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7M27_00601	COG0367	asparagine synthase
C7M27_00602	COG1113	amino acid transport
C7M27_00603	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M27_00604	COG2267	carboxylic ester hydrolase activity
C7M27_00606	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M27_00607	COG1242	4 iron, 4 sulfur cluster binding
C7M27_00610	COG1725	Transcriptional regulator
C7M27_00611	COG1131	(ABC) transporter
C7M27_00614	COG1136	(ABC) transporter
C7M27_00615	COG0577	efflux transmembrane transporter activity
C7M27_00616	COG0745	RESPONSE REGULATOR receiver
C7M27_00617	COG2205	protein histidine kinase activity
C7M27_00618	COG1136	(ABC) transporter
C7M27_00619	COG0577	efflux transmembrane transporter activity
C7M27_00620	COG2433	Pfam Transposase IS66
C7M27_00621	COG2814	Major facilitator Superfamily
C7M27_00622	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M27_00622	COG2202	Pas domain
C7M27_00624	COG0495	leucyl-tRNA aminoacylation
C7M27_00625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M27_00626	COG1486	melibiose metabolic process
C7M27_00627	COG0395	ABC-type sugar transport system, permease component
C7M27_00628	COG1175	transmembrane transport
C7M27_00629	COG1653	transport
C7M27_00630	COG1609	Transcriptional regulator
C7M27_00631	COG1073	alpha beta
C7M27_00633	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M27_00634	COG0156	8-amino-7-oxononanoate synthase activity
C7M27_00636	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7M27_00637	COG2124	cytochrome p450
C7M27_00638	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M27_00639	COG0395	ABC-type sugar transport system, permease component
C7M27_00640	COG1653	transport
C7M27_00641	COG2207	Transcriptional regulator
C7M27_00642	COG4209	transmembrane transport
C7M27_00643	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M27_00644	COG1653	transport
C7M27_00645	COG0673	inositol 2-dehydrogenase activity
C7M27_00646	COG5578	integral membrane protein
C7M27_00648	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M27_00649	COG2081	HI0933 family
C7M27_00650	COG2244	polysaccharide biosynthetic process
C7M27_00651	COG1187	pseudouridine synthase activity
C7M27_00652	COG1349	DNA-binding transcription factor activity
C7M27_00653	COG1131	(ABC) transporter
C7M27_00654	COG4473	ABC transporter
C7M27_00655	COG2252	PERMEase
C7M27_00656	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M27_00657	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M27_00658	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M27_00660	COG1597	lipid kinase activity
C7M27_00661	COG1523	belongs to the glycosyl hydrolase 13 family
C7M27_00662	COG0510	thiamine kinase activity
C7M27_00664	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7M27_00665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M27_00666	COG0281	malic enzyme
C7M27_00667	COG5584	Small secreted protein
C7M27_00668	COG1363	Peptidase, m42
C7M27_00670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_00671	COG4848	Belongs to the UPF0354 family
C7M27_00672	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M27_00673	COG1674	ftsk spoiiie
C7M27_00674	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7M27_00675	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M27_00676	COG4980	gas vesicle protein
C7M27_00677	COG3118	belongs to the thioredoxin family
C7M27_00678	COG1605	Chorismate mutase
C7M27_00678	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M27_00679	COG1609	Transcriptional regulator
C7M27_00680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M27_00681	COG1360	Flagellar Motor Protein
C7M27_00682	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7M27_00683	COG0517	IMP dehydrogenase activity
C7M27_00684	COG0454	-acetyltransferase
C7M27_00685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M27_00686	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M27_00688	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7M27_00689	COG2199	diguanylate cyclase activity
C7M27_00689	COG2203	Gaf domain
C7M27_00690	COG1956	GAF domain-containing protein
C7M27_00691	COG1309	transcriptional regulator
C7M27_00692	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M27_00693	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7M27_00694	COG1114	Component of the transport system for branched-chain amino acids
C7M27_00695	COG1104	cysteine desulfurase activity
C7M27_00696	COG0301	tRNA thio-modification
C7M27_00698	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M27_00699	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C7M27_00700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M27_00701	COG0616	signal peptide processing
C7M27_00702	COG1714	RDD family
C7M27_00704	COG3874	Sporulation protein YtfJ
C7M27_00705	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7M27_00706	COG0827	DNA restriction-modification system
C7M27_00707	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M27_00708	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7M27_00709	COG0137	argininosuccinate synthase activity
C7M27_00710	COG0165	Argininosuccinate lyase
C7M27_00712	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_00713	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7M27_00714	COG4109	DRTGG domain
C7M27_00716	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M27_00720	COG0587	DNA-directed DNA polymerase activity
C7M27_00721	COG0281	malic enzyme
C7M27_00722	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7M27_00723	COG0825	malonyl-CoA metabolic process
C7M27_00724	COG0205	6-phosphofructokinase activity
C7M27_00725	COG0469	pyruvate kinase activity
C7M27_00726	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7M27_00727	COG0628	permease
C7M27_00728	COG2707	UPF0756 membrane protein
C7M27_00729	COG0372	Belongs to the citrate synthase family
C7M27_00730	COG0538	isocitrate dehydrogenase activity
C7M27_00731	COG0039	L-malate dehydrogenase activity
C7M27_00732	COG0745	RESPONSE REGULATOR receiver
C7M27_00733	COG5002	protein histidine kinase activity
C7M27_00734	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M27_00734	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M27_00735	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M27_00736	COG1971	Probably functions as a manganese efflux pump
C7M27_00737	COG0237	dephospho-CoA kinase activity
C7M27_00738	COG0656	L-ascorbic acid biosynthetic process
C7M27_00739	COG2814	Major facilitator Superfamily
C7M27_00740	COG1733	regulation of RNA biosynthetic process
C7M27_00741	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M27_00742	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C7M27_00743	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7M27_00744	COG3611	Membrane attachment protein
C7M27_00745	COG1484	DNA-dependent DNA replication
C7M27_00746	COG0398	Pfam SNARE associated Golgi protein
C7M27_00749	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M27_00750	COG1011	Hydrolase
C7M27_00751	COG3275	phosphorelay sensor kinase activity
C7M27_00752	COG3279	Response regulator of the LytR AlgR family
C7M27_00753	COG1380	Effector of murein hydrolase LrgA
C7M27_00754	COG1346	cytolysis
C7M27_00756	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M27_00757	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7M27_00758	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7M27_00759	COG3326	Membrane
C7M27_00761	COG1363	Peptidase, m42
C7M27_00762	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M27_00763	COG2160	L-arabinose isomerase activity
C7M27_00764	COG1069	ribulokinase activity
C7M27_00765	COG0235	Class ii aldolase
C7M27_00766	COG0647	UMP catabolic process
C7M27_00767	COG0371	Dehydrogenase
C7M27_00768	COG1653	transport
C7M27_00769	COG1175	transmembrane transport
C7M27_00770	COG0395	ABC-type sugar transport system, permease component
C7M27_00771	COG3534	alpha-L-arabinofuranosidase
C7M27_00772	COG1966	Carbon starvation protein
C7M27_00773	COG0346	lactoylglutathione lyase activity
C7M27_00774	COG0247	lactate metabolic process
C7M27_00775	COG0277	FAD linked oxidase domain protein
C7M27_00776	COG3835	regulator
C7M27_00778	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M27_00779	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M27_00780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M27_00780	COG0072	phenylalanine-tRNA ligase activity
C7M27_00781	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M27_00782	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C7M27_00783	COG1286	toxin biosynthetic process
C7M27_00784	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M27_00784	COG1796	DNA polymerase
C7M27_00785	COG1193	negative regulation of DNA recombination
C7M27_00786	COG3766	membrane
C7M27_00787	COG0318	PFAM AMP-dependent synthetase and ligase
C7M27_00788	COG1309	transcriptional regulator
C7M27_00789	COG1024	Enoyl-CoA hydratase
C7M27_00790	COG2086	electron transfer activity
C7M27_00791	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M27_00793	COG3534	alpha-L-arabinofuranosidase
C7M27_00794	COG3118	belongs to the thioredoxin family
C7M27_00795	COG0322	excinuclease ABC activity
C7M27_00796	COG0527	aspartate kinase activity
C7M27_00797	COG1719	4-vinyl reductase, 4VR
C7M27_00798	COG2009	succinate dehydrogenase
C7M27_00799	COG1053	succinate dehydrogenase
C7M27_00800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7M27_00801	COG0824	Thioesterase
C7M27_00802	COG2197	response regulator
C7M27_00803	COG1846	Transcriptional regulator
C7M27_00804	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M27_00805	COG5401	PFAM Sporulation and spore germination
C7M27_00806	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7M27_00807	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M27_00808	COG0622	Phosphoesterase
C7M27_00810	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
C7M27_00811	COG0454	-acetyltransferase
C7M27_00813	COG0028	Belongs to the TPP enzyme family
C7M27_00814	COG0440	acetolactate synthase activity
C7M27_00815	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7M27_00816	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M27_00817	COG0473	3-isopropylmalate dehydrogenase activity
C7M27_00818	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7M27_00819	COG0066	3-isopropylmalate dehydratase activity
C7M27_00820	COG0457	Tetratricopeptide repeat
C7M27_00820	COG1477	protein flavinylation
C7M27_00821	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7M27_00822	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7M27_00823	COG0470	DNA polymerase III
C7M27_00823	COG1067	ATP-dependent peptidase activity
C7M27_00824	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7M27_00825	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7M27_00827	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7M27_00828	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M27_00829	COG0181	hydroxymethylbilane synthase activity
C7M27_00830	COG1587	Uroporphyrinogen-III synthase
C7M27_00831	COG0113	porphobilinogen synthase activity
C7M27_00832	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M27_00833	COG1388	LysM domain
C7M27_00834	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M27_00836	COG0525	valine-tRNA ligase activity
C7M27_00837	COG0285	dihydrofolate synthase activity
C7M27_00838	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M27_00840	COG0424	maF-like protein
C7M27_00841	COG2003	Belongs to the UPF0758 family
C7M27_00842	COG1077	Cell shape determining protein MreB Mrl
C7M27_00844	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7M27_00845	COG0850	regulation of cytokinetic process
C7M27_00846	COG2894	cell division
C7M27_00847	COG0739	heme binding
C7M27_00848	COG1994	Peptidase M50
C7M27_00849	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7M27_00850	COG2868	ribosomal protein
C7M27_00851	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M27_00852	COG3290	protein histidine kinase activity
C7M27_00853	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7M27_00854	COG4492	Belongs to the UPF0735 family
C7M27_00855	COG0077	Prephenate dehydratase
C7M27_00856	COG1827	regulation of RNA biosynthetic process
C7M27_00857	COG1104	cysteine desulfurase activity
C7M27_00858	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7M27_00859	COG0157	Belongs to the NadC ModD family
C7M27_00860	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7M27_00861	COG1388	LysM domain
C7M27_00863	COG0217	transcriptional regulatory protein
C7M27_00864	COG1115	amino acid carrier protein
C7M27_00867	COG2112	serine threonine protein kinase
C7M27_00868	COG0673	inositol 2-dehydrogenase activity
C7M27_00869	COG2814	Major facilitator Superfamily
C7M27_00871	COG0632	four-way junction helicase activity
C7M27_00872	COG2255	four-way junction helicase activity
C7M27_00874	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7M27_00875	COG0343	queuine tRNA-ribosyltransferase activity
C7M27_00876	COG1862	Preprotein translocase
C7M27_00878	COG2323	membrane
C7M27_00879	COG2244	polysaccharide biosynthetic process
C7M27_00881	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M27_00881	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M27_00882	COG0490	domain, Protein
C7M27_00883	COG5416	Lipopolysaccharide assembly protein A domain
C7M27_00884	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M27_00884	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M27_00885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M27_00886	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M27_00887	COG1490	D-aminoacyl-tRNA deacylase activity
C7M27_00888	COG4991	sh3 domain protein
C7M27_00888	COG3103	Sh3 type 3 domain protein
C7M27_00888	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M27_00890	COG0124	histidyl-tRNA synthetase
C7M27_00891	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7M27_00892	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7M27_00893	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M27_00894	COG1959	2 iron, 2 sulfur cluster binding
C7M27_00895	COG1104	cysteine desulfurase activity
C7M27_00896	COG0482	sulfurtransferase activity
C7M27_00897	COG0457	Tetratricopeptide repeat
C7M27_00898	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M27_00899	COG3881	PFAM PRC-barrel domain
C7M27_00902	COG0765	amino acid transport
C7M27_00903	COG0765	amino acid transport
C7M27_00904	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M27_00905	COG1126	abc transporter atp-binding protein
C7M27_00906	COG0628	permease
C7M27_00907	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7M27_00908	COG4472	Bacterial protein of unknown function (DUF965)
C7M27_00909	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7M27_00910	COG3906	Belongs to the UPF0473 family
C7M27_00911	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M27_00912	COG4122	O-methyltransferase activity
C7M27_00915	COG0572	uridine kinase
C7M27_00916	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M27_00917	COG0768	penicillin binding
C7M27_00920	COG2226	methyltransferase
C7M27_00921	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7M27_00922	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M27_00923	COG0626	cystathionine gamma-synthase activity
C7M27_00925	COG2427	Protein of unknown function (DUF1641)
C7M27_00926	COG3383	formate dehydrogenase (NAD+) activity
C7M27_00927	COG5609	conserved protein (DUF2294)
C7M27_00928	COG2116	formate transmembrane transporter activity
C7M27_00931	COG2226	methyltransferase
C7M27_00932	COG1309	transcriptional regulator
C7M27_00933	COG2124	cytochrome p450
C7M27_00933	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M27_00935	COG2755	lipolytic protein G-D-S-L family
C7M27_00935	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M27_00937	COG1595	DNA-templated transcription, initiation
C7M27_00938	COG1378	Sugar-specific transcriptional regulator TrmB
C7M27_00939	COG1280	lysine exporter protein (LysE YggA)
C7M27_00940	COG1113	amino acid transport
C7M27_00941	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7M27_00941	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M27_00942	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M27_00943	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M27_00944	COG3715	PTS system
C7M27_00945	COG3716	PTS system mannose fructose sorbose family IID component
C7M27_00946	COG1621	beta-fructofuranosidase activity
C7M27_00947	COG0693	protein deglycase activity
C7M27_00948	COG1064	alcohol dehydrogenase
C7M27_00950	COG0789	Transcriptional regulator
C7M27_00951	COG5577	PFAM Coat F domain
C7M27_00953	COG1063	alcohol dehydrogenase
C7M27_00954	COG5577	PFAM Coat F domain
C7M27_00956	COG0346	lactoylglutathione lyase activity
C7M27_00957	COG4991	sh3 domain protein
C7M27_00958	COG4991	sh3 domain protein
C7M27_00959	COG0596	Alpha beta hydrolase
C7M27_00960	COG5566	PFAM Mor transcription activator
C7M27_00961	COG3409	Peptidoglycan-binding domain 1 protein
C7M27_00962	COG0667	Aldo Keto reductase
C7M27_00963	COG1595	DNA-templated transcription, initiation
C7M27_00964	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7M27_00965	COG1846	Transcriptional regulator
C7M27_00966	COG0477	Major facilitator Superfamily
C7M27_00968	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M27_00969	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7M27_00970	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_00973	COG2186	Transcriptional regulator
C7M27_00975	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M27_00976	COG2070	2-Nitropropane dioxygenase
C7M27_00978	COG2318	DinB family
C7M27_00980	COG1335	isochorismatase
C7M27_00981	COG2124	cytochrome p450
C7M27_00982	COG2732	(Barnase) inhibitor
C7M27_00983	COG1522	sequence-specific DNA binding
C7M27_00984	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C7M27_00985	COG1687	branched-chain amino acid
C7M27_00986	COG1114	Component of the transport system for branched-chain amino acids
C7M27_00988	COG1230	cation diffusion facilitator family transporter
C7M27_00989	COG2072	flavoprotein involved in K transport
C7M27_00990	COG0583	DNA-binding transcription factor activity
C7M27_00991	COG0697	spore germination
C7M27_00993	COG1253	flavin adenine dinucleotide binding
C7M27_00994	COG0456	acetyltransferase
C7M27_00995	COG2814	Major facilitator Superfamily
C7M27_00996	COG4978	Transcriptional regulator
C7M27_00996	COG0789	Transcriptional regulator
C7M27_00997	COG0662	Cupin 2, conserved barrel domain protein
C7M27_00999	COG1937	Protein conserved in bacteria
C7M27_01000	COG2210	Belongs to the sulfur carrier protein TusA family
C7M27_01001	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M27_01001	COG0425	Belongs to the sulfur carrier protein TusA family
C7M27_01002	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M27_01002	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M27_01003	COG0425	Belongs to the sulfur carrier protein TusA family
C7M27_01004	COG0730	response to heat
C7M27_01006	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M27_01007	COG0454	-acetyltransferase
C7M27_01008	COG2311	Membrane
C7M27_01009	COG0745	RESPONSE REGULATOR receiver
C7M27_01010	COG5002	protein histidine kinase activity
C7M27_01010	COG0642	Histidine kinase
C7M27_01011	COG3223	Belongs to the PsiE family
C7M27_01013	COG3209	COG3209 Rhs family protein
C7M27_01015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7M27_01016	COG0398	Pfam SNARE associated Golgi protein
C7M27_01017	COG3409	Peptidoglycan-binding domain 1 protein
C7M27_01017	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M27_01018	COG2755	lipolytic protein G-D-S-L family
C7M27_01020	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7M27_01021	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M27_01022	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M27_01023	COG1534	Rna-binding protein
C7M27_01024	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7M27_01025	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M27_01026	COG0799	negative regulation of ribosome biogenesis
C7M27_01027	COG2226	methyltransferase
C7M27_01028	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M27_01029	COG1596	polysaccharide export
C7M27_01029	COG1555	photosystem II stabilization
C7M27_01030	COG2131	deaminase
C7M27_01031	COG2333	competence protein COMEC
C7M27_01031	COG0658	competence protein
C7M27_01033	COG1466	dna polymerase III delta subunit
C7M27_01034	COG0268	Binds directly to 16S ribosomal RNA
C7M27_01035	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7M27_01036	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M27_01038	COG0481	GTPase activity
C7M27_01039	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M27_01040	COG1420	regulation of RNA biosynthetic process
C7M27_01041	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7M27_01042	COG0443	Heat shock 70 kDa protein
C7M27_01043	COG0484	heat shock protein binding
C7M27_01044	COG2264	protein methyltransferase activity
C7M27_01045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M27_01046	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M27_01047	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M27_01049	COG1610	YqeY-like protein
C7M27_01050	COG1030	water channel activity
C7M27_01051	COG4864	UPF0365 protein
C7M27_01054	COG0561	phosphatase activity
C7M27_01055	COG1702	phosphate starvation-inducible protein PhoH
C7M27_01057	COG1480	7TM receptor with intracellular HD hydrolase
C7M27_01058	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7M27_01059	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M27_01060	COG0295	cytidine deaminase activity
C7M27_01061	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M27_01063	COG1381	Involved in DNA repair and RecF pathway recombination
C7M27_01064	COG0752	glycyl-tRNA synthetase alpha subunit
C7M27_01065	COG0751	glycine-tRNA ligase activity
C7M27_01066	COG0517	IMP dehydrogenase activity
C7M27_01067	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7M27_01068	COG1671	Belongs to the UPF0178 family
C7M27_01069	COG0358	DNA primase activity
C7M27_01070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M27_01071	COG2010	Cytochrome c
C7M27_01072	COG2384	SAM-dependent methyltransferase
C7M27_01073	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M27_01074	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7M27_01076	COG0513	Belongs to the DEAD box helicase family
C7M27_01077	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7M27_01079	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M27_01080	COG0735	belongs to the Fur family
C7M27_01081	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C7M27_01082	COG4709	membrane
C7M27_01083	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7M27_01084	COG1388	LysM domain
C7M27_01085	COG5521	maltodextrose utilization protein MalA
C7M27_01086	COG2839	Protein conserved in bacteria
C7M27_01087	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M27_01088	COG0477	Major facilitator Superfamily
C7M27_01090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M27_01091	COG0573	inorganic phosphate transmembrane transporter activity
C7M27_01092	COG0581	inorganic phosphate transmembrane transporter activity
C7M27_01093	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M27_01094	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M27_01095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M27_01098	COG0438	transferase activity, transferring glycosyl groups
C7M27_01100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M27_01102	COG0705	Rhomboid family
C7M27_01102	COG0457	Tetratricopeptide repeat
C7M27_01103	COG4483	Protein conserved in bacteria
C7M27_01104	COG1940	carbohydrate kinase activity
C7M27_01105	COG1368	sulfuric ester hydrolase activity
C7M27_01106	COG2866	Carboxypeptidase
C7M27_01108	COG0011	TIGRFAM Protein of
C7M27_01110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M27_01112	COG1393	Belongs to the ArsC family
C7M27_01114	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M27_01115	COG1253	flavin adenine dinucleotide binding
C7M27_01116	COG0598	Magnesium transport protein CorA
C7M27_01117	COG0517	IMP dehydrogenase activity
C7M27_01119	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M27_01120	COG1459	type II secretion system
C7M27_01121	COG4537	Required for transformation and DNA binding
C7M27_01122	COG4970	Tfp pilus assembly protein FimT
C7M27_01124	COG4940	Competence protein ComGF
C7M27_01129	COG0681	Belongs to the peptidase S26 family
C7M27_01131	COG1396	sequence-specific DNA binding
C7M27_01134	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M27_01135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7M27_01136	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M27_01137	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M27_01138	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M27_01139	COG0095	Lipoate-protein ligase
C7M27_01140	COG1321	iron dependent repressor
C7M27_01141	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M27_01143	COG3872	metal-dependent enzyme
C7M27_01145	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7M27_01146	COG0006	proline dipeptidase activity
C7M27_01147	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7M27_01149	COG3854	ATPases associated with a variety of cellular activities
C7M27_01157	COG0511	ligase activity, forming carbon-carbon bonds
C7M27_01158	COG0439	Biotin carboxylase
C7M27_01159	COG1302	Protein conserved in bacteria
C7M27_01160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M27_01161	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7M27_01162	COG1570	exodeoxyribonuclease VII activity
C7M27_01163	COG1722	exodeoxyribonuclease VII activity
C7M27_01164	COG0142	geranyltranstransferase activity
C7M27_01165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7M27_01166	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M27_01167	COG1438	arginine binding
C7M27_01168	COG0497	DNA recombination
C7M27_01169	COG0750	zinc metalloprotease
C7M27_01170	COG0745	RESPONSE REGULATOR receiver
C7M27_01172	COG1902	pentaerythritol trinitrate reductase activity
C7M27_01174	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M27_01175	COG0584	glycerophosphoryl diester phosphodiesterase
C7M27_01176	COG0183	Belongs to the thiolase family
C7M27_01177	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M27_01178	COG1960	acyl-CoA dehydrogenase activity
C7M27_01179	COG0372	Belongs to the citrate synthase family
C7M27_01180	COG2079	MmgE PrpD family protein
C7M27_01181	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7M27_01183	COG3290	protein histidine kinase activity
C7M27_01183	COG3829	transcription factor binding
C7M27_01184	COG0280	phosphate acetyltransferase
C7M27_01185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M27_01186	COG3426	butyrate kinase activity
C7M27_01187	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M27_01188	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M27_01189	COG0022	dehydrogenase e1 component
C7M27_01190	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M27_01191	COG4978	Transcriptional regulator
C7M27_01191	COG0789	Transcriptional regulator
C7M27_01192	COG2814	Major facilitator Superfamily
C7M27_01193	COG1597	lipid kinase activity
C7M27_01195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M27_01196	COG0765	amino acid transport
C7M27_01197	COG1126	abc transporter atp-binding protein
C7M27_01198	COG4129	membrane
C7M27_01199	COG1376	ErfK ybiS ycfS ynhG family protein
C7M27_01201	COG0346	lactoylglutathione lyase activity
C7M27_01202	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M27_01203	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M27_01204	COG3361	conserved protein (COG2071)
C7M27_01205	COG0706	membrane insertase activity
C7M27_01207	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M27_01208	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M27_01209	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M27_01210	COG1234	tRNA 3'-trailer cleavage
C7M27_01212	COG0596	Alpha beta hydrolase
C7M27_01213	COG1902	pentaerythritol trinitrate reductase activity
C7M27_01214	COG4187	Peptidase family M20/M25/M40
C7M27_01215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M27_01216	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M27_01217	COG0300	oxidoreductase activity
C7M27_01218	COG3048	D-serine ammonia-lyase activity
C7M27_01219	COG1072	(Pantothenic acid kinase))
C7M27_01220	COG0346	lactoylglutathione lyase activity
C7M27_01222	COG2211	Major facilitator Superfamily
C7M27_01224	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M27_01226	COG0456	acetyltransferase
C7M27_01227	COG2329	Antibiotic biosynthesis monooxygenase
C7M27_01228	COG0456	acetyltransferase
C7M27_01228	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M27_01229	COG4918	Iron-sulphur cluster biosynthesis
C7M27_01231	COG1073	alpha beta
C7M27_01233	COG0667	Aldo Keto reductase
C7M27_01235	COG0494	nUDIX hydrolase
C7M27_01236	COG1379	DNA repair
C7M27_01237	COG1396	sequence-specific DNA binding
C7M27_01238	COG0252	asparaginase activity
C7M27_01239	COG1027	Aspartate ammonia-lyase
C7M27_01240	COG1757	Na H antiporter
C7M27_01241	COG0281	malic enzyme
C7M27_01243	COG1300	Membrane
C7M27_01244	COG0735	belongs to the Fur family
C7M27_01246	COG4974	Belongs to the 'phage' integrase family
C7M27_01247	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M27_01248	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7M27_01249	COG1686	Belongs to the peptidase S11 family
C7M27_01250	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M27_01251	COG2172	sigma factor antagonist activity
C7M27_01252	COG1191	sigma factor activity
C7M27_01256	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M27_01259	COG0697	spore germination
C7M27_01260	COG0019	diaminopimelate decarboxylase activity
C7M27_01261	COG4086	secreted protein
C7M27_01262	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M27_01264	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
C7M27_01265	COG0681	Belongs to the peptidase S26 family
C7M27_01267	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M27_01267	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M27_01268	COG0307	riboflavin synthase, alpha
C7M27_01269	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M27_01269	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M27_01270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7M27_01271	COG0456	acetyltransferase
C7M27_01272	COG1547	Domain of unknown function (DUF309)
C7M27_01273	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7M27_01274	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7M27_01276	COG1686	Belongs to the peptidase S11 family
C7M27_01277	COG2715	membrane protein required for spore maturation
C7M27_01278	COG0700	Nucleoside recognition
C7M27_01279	COG1187	pseudouridine synthase activity
C7M27_01280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_01281	COG1333	cytochrome c biogenesis protein
C7M27_01282	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M27_01283	COG0745	RESPONSE REGULATOR receiver
C7M27_01284	COG5002	protein histidine kinase activity
C7M27_01285	COG1595	DNA-templated transcription, initiation
C7M27_01287	COG0710	3-dehydroquinate dehydratase activity
C7M27_01288	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M27_01289	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M27_01290	COG1141	Ferredoxin
C7M27_01291	COG4955	Helix-turn-helix domain
C7M27_01292	COG0514	ATP-dependent DNA helicase (RecQ)
C7M27_01293	COG1266	CAAX protease self-immunity
C7M27_01294	COG1388	LysM domain
C7M27_01296	COG1408	metallophosphoesterase
C7M27_01297	COG4862	establishment of competence for transformation
C7M27_01298	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M27_01299	COG0492	ferredoxin-NADP+ reductase activity
C7M27_01300	COG2339	peptidase activity
C7M27_01301	COG3409	Peptidoglycan-binding domain 1 protein
C7M27_01301	COG3773	Cell wall hydrolase
C7M27_01302	COG2959	enzyme of heme biosynthesis
C7M27_01303	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7M27_01305	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7M27_01306	COG0539	negative regulation of cytoplasmic translation
C7M27_01307	COG1304	FMN binding
C7M27_01312	COG1160	GTP binding
C7M27_01313	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7M27_01316	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M27_01317	COG0776	regulation of translation
C7M27_01318	COG0302	gtp cyclohydrolase
C7M27_01320	COG0142	geranyltranstransferase activity
C7M27_01321	COG2226	methyltransferase
C7M27_01322	COG0142	geranyltranstransferase activity
C7M27_01323	COG0105	UTP biosynthetic process
C7M27_01324	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7M27_01325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7M27_01326	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7M27_01327	COG4401	Chorismate mutase type I
C7M27_01328	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M27_01329	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M27_01331	COG0135	phosphoribosylanthranilate isomerase activity
C7M27_01332	COG0133	tryptophan synthase activity
C7M27_01333	COG0159	tryptophan synthase activity
C7M27_01335	COG0287	Prephenate dehydrogenase
C7M27_01336	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7M27_01337	COG0457	Tetratricopeptide repeat
C7M27_01338	COG5582	Belongs to the UPF0302 family
C7M27_01340	COG0723	plastoquinol--plastocyanin reductase activity
C7M27_01341	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M27_01342	COG2010	Cytochrome c
C7M27_01342	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M27_01343	COG4347	Protein of unknown function (DUF1405)
C7M27_01345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M27_01346	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M27_01347	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7M27_01348	COG1803	Methylglyoxal synthase
C7M27_01349	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M27_01350	COG0438	transferase activity, transferring glycosyl groups
C7M27_01351	COG0617	tRNA 3'-terminal CCA addition
C7M27_01352	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C7M27_01352	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C7M27_01353	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7M27_01354	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7M27_01355	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7M27_01356	COG1199	ATP-dependent helicase activity
C7M27_01356	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M27_01358	COG5353	protein conserved in bacteria
C7M27_01359	COG0436	Aminotransferase
C7M27_01360	COG0017	Asparaginyl-tRNA synthetase
C7M27_01361	COG3935	DnaD domain protein
C7M27_01362	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M27_01364	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M27_01364	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M27_01365	COG3331	DNA recombination
C7M27_01372	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M27_01373	COG2190	(PTS) system
C7M27_01374	COG1111	helicase
C7M27_01374	COG1205	dead DEAH box helicase
C7M27_01375	COG3359	exonuclease
C7M27_01376	COG4474	Belongs to the UPF0398 family
C7M27_01378	COG0116	Belongs to the methyltransferase superfamily
C7M27_01380	COG1199	ATP-dependent helicase activity
C7M27_01381	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_01382	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C7M27_01383	COG1609	Transcriptional regulator
C7M27_01384	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M27_01385	COG0800	Aldolase
C7M27_01387	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7M27_01388	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M27_01389	COG2233	PERMEase
C7M27_01390	COG3424	synthase
C7M27_01391	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7M27_01392	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M27_01395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M27_01397	COG0328	RNA-DNA hybrid ribonuclease activity
C7M27_01398	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7M27_01399	COG0328	RNA-DNA hybrid ribonuclease activity
C7M27_01403	COG1278	Cold shock
C7M27_01404	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M27_01405	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7M27_01406	COG0386	Belongs to the glutathione peroxidase family
C7M27_01407	COG1418	mRNA catabolic process
C7M27_01408	COG1413	lyase activity
C7M27_01409	COG0129	dihydroxy-acid dehydratase activity
C7M27_01411	COG2521	methyltransferase
C7M27_01411	COG2136	Putative SAM-dependent methyltransferase
C7M27_01413	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M27_01414	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M27_01415	COG0204	Acyl-transferase
C7M27_01416	COG1272	protein, Hemolysin III
C7M27_01417	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M27_01418	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M27_01420	COG1999	signal sequence binding
C7M27_01421	COG2755	lipolytic protein G-D-S-L family
C7M27_01422	COG4698	Protein conserved in bacteria
C7M27_01424	COG0534	Mate efflux family protein
C7M27_01425	COG1846	Transcriptional regulator
C7M27_01426	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M27_01427	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M27_01428	COG1086	Polysaccharide biosynthesis protein
C7M27_01429	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M27_01433	COG1525	nuclease
C7M27_01435	COG4282	regulation of fungal-type cell wall biogenesis
C7M27_01436	COG5444	nuclease activity
C7M27_01442	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M27_01445	COG2274	protein secretion by the type I secretion system
C7M27_01445	COG3271	cysteine-type peptidase activity
C7M27_01446	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_01447	COG0463	Glycosyl transferase, family 2
C7M27_01448	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M27_01451	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M27_01457	COG2433	Pfam Transposase IS66
C7M27_01459	COG1196	nuclear chromosome segregation
C7M27_01459	COG0741	lytic transglycosylase activity
C7M27_01459	COG0739	heme binding
C7M27_01460	COG0741	lytic transglycosylase activity
C7M27_01460	COG0739	heme binding
C7M27_01460	COG1196	nuclear chromosome segregation
C7M27_01464	COG0582	viral genome integration into host DNA
C7M27_01483	COG4373	Mu-like prophage FluMu protein gp28
C7M27_01489	COG0776	regulation of translation
C7M27_01494	COG1395	domain, Protein
C7M27_01512	COG3655	Transcriptional regulator
C7M27_01530	COG0582	viral genome integration into host DNA
C7M27_01533	COG3655	Transcriptional regulator
C7M27_01544	COG1388	LysM domain
C7M27_01547	COG4474	Belongs to the UPF0398 family
C7M27_01552	COG0756	dUTP diphosphatase activity
C7M27_01555	COG1793	dna ligase
C7M27_01556	COG2135	peptidase activity
C7M27_01564	COG2887	Belongs to the helicase family. UvrD subfamily
C7M27_01566	COG0305	Participates in initiation and elongation during chromosome replication
C7M27_01567	COG0358	DNA primase activity
C7M27_01568	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M27_01569	COG0587	DNA-directed DNA polymerase activity
C7M27_01570	COG3584	3D domain protein
C7M27_01576	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M27_01594	COG1780	Probably involved in ribonucleotide reductase function
C7M27_01595	COG1372	Participates in initiation and elongation during chromosome replication
C7M27_01595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M27_01596	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M27_01598	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M27_01599	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_01601	COG0756	dUTP diphosphatase activity
C7M27_01617	COG3331	DNA recombination
C7M27_01619	COG1086	Polysaccharide biosynthesis protein
C7M27_01620	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
C7M27_01621	COG4641	Protein conserved in bacteria
C7M27_01624	COG0463	Glycosyl transferase, family 2
C7M27_01625	COG0456	acetyltransferase
C7M27_01627	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M27_01628	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M27_01629	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M27_01630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M27_01631	COG0456	acetyltransferase
C7M27_01632	COG1509	lysine 2,3-aminomutase activity
C7M27_01634	COG4479	Belongs to the UPF0346 family
C7M27_01638	COG0671	phosphoesterase, PA-phosphatase related
C7M27_01641	COG0813	purine-nucleoside phosphorylase activity
C7M27_01642	COG1876	peptidase activity
C7M27_01644	COG2226	methyltransferase
C7M27_01645	COG0793	Belongs to the peptidase S41A family
C7M27_01645	COG3409	Peptidoglycan-binding domain 1 protein
C7M27_01646	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M27_01648	COG0346	lactoylglutathione lyase activity
C7M27_01649	COG0400	carboxylic ester hydrolase activity
C7M27_01650	COG0778	Nitroreductase
C7M27_01651	COG1733	regulation of RNA biosynthetic process
C7M27_01652	COG1942	4-Oxalocrotonate Tautomerase
C7M27_01653	COG2610	gluconate transmembrane transporter activity
C7M27_01654	COG2610	gluconate transmembrane transporter activity
C7M27_01657	COG2962	Rard protein
C7M27_01659	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M27_01660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M27_01661	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M27_01662	COG0534	Mate efflux family protein
C7M27_01664	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M27_01665	COG1819	glycosyl
C7M27_01666	COG0791	NLP P60 protein
C7M27_01666	COG1388	LysM domain
C7M27_01667	COG2032	superoxide dismutase activity
C7M27_01668	COG0714	Associated with various cellular activities
C7M27_01669	COG4548	von Willebrand factor, type A
C7M27_01670	COG0567	Dehydrogenase, E1 component
C7M27_01671	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M27_01672	COG0385	Bile acid
C7M27_01673	COG0733	neurotransmitter:sodium symporter activity
C7M27_01674	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M27_01675	COG1657	PFAM Prenyltransferase squalene oxidase
C7M27_01676	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_01681	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M27_01684	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M27_01685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M27_01686	COG0514	ATP-dependent DNA helicase (RecQ)
C7M27_01687	COG3584	3D domain protein
C7M27_01687	COG1388	LysM domain
C7M27_01688	COG2197	response regulator
C7M27_01689	COG4585	Histidine kinase
C7M27_01690	COG3239	Fatty acid desaturase
C7M27_01691	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M27_01694	COG2322	membrane
C7M27_01695	COG0741	lytic transglycosylase activity
C7M27_01696	COG0640	Transcriptional regulator
C7M27_01698	COG2378	regulation of single-species biofilm formation
C7M27_01699	COG3708	Transcriptional regulator
C7M27_01700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M27_01701	COG1309	transcriptional regulator
C7M27_01702	COG0456	acetyltransferase
C7M27_01703	COG0662	Cupin 2, conserved barrel domain protein
C7M27_01703	COG2207	Transcriptional regulator
C7M27_01704	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M27_01705	COG1231	oxidoreductase activity
C7M27_01706	COG4282	regulation of fungal-type cell wall biogenesis
C7M27_01707	COG5444	nuclease activity
C7M27_01712	COG0726	polysaccharide deacetylase
C7M27_01713	COG0574	Belongs to the PEP-utilizing enzyme family
C7M27_01713	COG3848	Pyruvate phosphate dikinase
C7M27_01716	COG2367	Beta-lactamase
C7M27_01717	COG0693	protein deglycase activity
C7M27_01719	COG0697	spore germination
C7M27_01720	COG0583	DNA-binding transcription factor activity
C7M27_01721	COG3739	integral membrane protein
C7M27_01722	COG3655	Transcriptional regulator
C7M27_01724	COG2720	vancomycin resistance protein
C7M27_01727	COG2140	Oxalate decarboxylase
C7M27_01730	COG2135	peptidase activity
C7M27_01731	COG3866	Pectate lyase
C7M27_01732	COG3619	membrane
C7M27_01733	COG4305	rare lipoprotein A
C7M27_01734	COG2368	4-hydroxyphenylacetate
C7M27_01735	COG0840	transmembrane signaling receptor activity
C7M27_01735	COG5278	phosphoserine phosphatase activity
C7M27_01739	COG1609	Transcriptional regulator
C7M27_01740	COG1082	Xylose isomerase domain protein TIM barrel
C7M27_01741	COG0673	inositol 2-dehydrogenase activity
C7M27_01742	COG2814	Major facilitator Superfamily
C7M27_01744	COG0243	molybdopterin cofactor binding
C7M27_01745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M27_01746	COG1070	Carbohydrate kinase
C7M27_01747	COG2814	Major facilitator Superfamily
C7M27_01749	COG1131	(ABC) transporter
C7M27_01752	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M27_01754	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M27_01755	COG0300	oxidoreductase activity
C7M27_01757	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M27_01758	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M27_01759	COG0583	DNA-binding transcription factor activity
C7M27_01760	COG0067	glutamate synthase
C7M27_01760	COG0069	glutamate synthase activity
C7M27_01760	COG0070	glutamate synthase
C7M27_01761	COG0493	'glutamate synthase
C7M27_01762	COG0604	alcohol dehydrogenase
C7M27_01763	COG0583	DNA-binding transcription factor activity
C7M27_01764	COG0405	Gamma-glutamyltransferase
C7M27_01765	COG0166	Belongs to the GPI family
C7M27_01766	COG0582	viral genome integration into host DNA
C7M27_01769	COG0534	Mate efflux family protein
C7M27_01770	COG2017	converts alpha-aldose to the beta-anomer
C7M27_01771	COG2027	D-alanyl-D-alanine carboxypeptidase
C7M27_01772	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_01773	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_01774	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_01775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_01776	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M27_01776	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_01778	COG1649	PFAM Uncharacterised BCR, COG1649
C7M27_01779	COG1960	acyl-CoA dehydrogenase activity
C7M27_01780	COG0318	PFAM AMP-dependent synthetase and ligase
C7M27_01781	COG0439	Biotin carboxylase
C7M27_01782	COG0511	ligase activity, forming carbon-carbon bonds
C7M27_01783	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M27_01784	COG1024	Enoyl-CoA hydratase
C7M27_01785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M27_01786	COG2404	hydrolase activity, acting on ester bonds
C7M27_01787	COG0586	Pfam SNARE associated Golgi protein
C7M27_01788	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M27_01789	COG2246	polysaccharide biosynthetic process
C7M27_01790	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M27_01791	COG5520	Belongs to the glycosyl hydrolase 30 family
C7M27_01793	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7M27_01794	COG1115	amino acid carrier protein
C7M27_01797	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M27_01798	COG0187	DNA topoisomerase II activity
C7M27_01799	COG1832	CoA-binding protein
C7M27_01800	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7M27_01801	COG4841	protein insertion into membrane
C7M27_01803	COG0824	Thioesterase
C7M27_01807	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_01808	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7M27_01811	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M27_01813	COG4846	Membrane protein involved in cytochrome C biogenesis
C7M27_01814	COG2201	protein-glutamate methylesterase activity
C7M27_01815	COG0785	Cytochrome C biogenesis protein
C7M27_01817	COG3763	UPF0154 protein
C7M27_01819	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M27_01820	COG4224	UPF0291 protein
C7M27_01821	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M27_01822	COG1388	LysM domain
C7M27_01823	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7M27_01824	COG0346	lactoylglutathione lyase activity
C7M27_01826	COG4195	phage-related replication protein
C7M27_01832	COG0531	amino acid
C7M27_01833	COG0697	spore germination
C7M27_01836	COG3832	glyoxalase III activity
C7M27_01838	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M27_01846	COG0756	dUTP diphosphatase activity
C7M27_01848	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M27_01849	COG2814	Major facilitator Superfamily
C7M27_01850	COG1525	nuclease
C7M27_01851	COG1070	Carbohydrate kinase
C7M27_01852	COG2115	Belongs to the xylose isomerase family
C7M27_01853	COG1940	carbohydrate kinase activity
C7M27_01854	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M27_01855	COG2211	Major facilitator Superfamily
C7M27_01856	COG0135	phosphoribosylanthranilate isomerase activity
C7M27_01858	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M27_01860	COG4282	regulation of fungal-type cell wall biogenesis
C7M27_01866	COG5444	nuclease activity
C7M27_01869	COG0174	glutamine synthetase
C7M27_01870	COG0789	Transcriptional regulator
C7M27_01871	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7M27_01872	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M27_01873	COG0464	growth
C7M27_01874	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M27_01875	COG4112	unkown
C7M27_01876	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M27_01877	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M27_01878	COG1780	Probably involved in ribonucleotide reductase function
C7M27_01881	COG1923	regulation of RNA biosynthetic process
C7M27_01882	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7M27_01885	COG2076	Multidrug Resistance protein
C7M27_01886	COG2076	Multidrug Resistance protein
C7M27_01887	COG1764	response to oxidative stress
C7M27_01888	COG4195	phage-related replication protein
C7M27_01890	COG1404	Belongs to the peptidase S8 family
C7M27_01891	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M27_01893	COG2124	cytochrome p450
C7M27_01894	COG3321	synthase
C7M27_01894	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7M27_01894	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M27_01894	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M27_01895	COG4221	oxidoreductase activity
C7M27_01895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_01895	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_01895	COG3321	synthase
C7M27_01896	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_01896	COG3321	synthase
C7M27_01896	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M27_01896	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M27_01896	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_01897	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M27_01897	COG4221	oxidoreductase activity
C7M27_01897	COG0300	oxidoreductase activity
C7M27_01897	COG3321	synthase
C7M27_01898	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_01898	COG0318	PFAM AMP-dependent synthetase and ligase
C7M27_01898	COG0300	oxidoreductase activity
C7M27_01898	COG3321	synthase
C7M27_01898	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_01899	COG1024	Enoyl-CoA hydratase
C7M27_01900	COG1024	Enoyl-CoA hydratase
C7M27_01901	COG3425	synthase
C7M27_01902	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M27_01903	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M27_01904	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M27_01904	COG2070	2-Nitropropane dioxygenase
C7M27_01905	COG3321	synthase
C7M27_01907	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M27_01908	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M27_01909	COG3226	Transcriptional regulator
C7M27_01913	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7M27_01914	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M27_01916	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7M27_01917	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M27_01918	COG0156	8-amino-7-oxononanoate synthase activity
C7M27_01919	COG1063	alcohol dehydrogenase
C7M27_01920	COG2359	stage V sporulation protein S
C7M27_01921	COG1692	metallophosphoesterase
C7M27_01922	COG1418	mRNA catabolic process
C7M27_01923	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M27_01924	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7M27_01925	COG1546	Belongs to the CinA family
C7M27_01925	COG1058	Belongs to the CinA family
C7M27_01926	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M27_01927	COG1426	Protein conserved in bacteria
C7M27_01930	COG0300	oxidoreductase activity
C7M27_01931	COG0612	Peptidase, M16
C7M27_01932	COG0612	Peptidase, M16
C7M27_01933	COG2814	Major facilitator Superfamily
C7M27_01934	COG2188	Transcriptional regulator
C7M27_01935	COG4980	gas vesicle protein
C7M27_01935	COG1674	ftsk spoiiie
C7M27_01937	COG0740	serine-type endopeptidase activity
C7M27_01938	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M27_01939	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M27_01940	COG0527	aspartate kinase activity
C7M27_01941	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M27_01942	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M27_01943	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M27_01944	COG1873	PFAM PRC-barrel domain
C7M27_01945	COG0612	Peptidase, M16
C7M27_01946	COG0726	polysaccharide deacetylase
C7M27_01947	COG1185	polyribonucleotide nucleotidyltransferase activity
C7M27_01948	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7M27_01949	COG0196	riboflavin kinase activity
C7M27_01950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7M27_01951	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7M27_01952	COG1550	Protein conserved in bacteria
C7M27_01953	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7M27_01954	COG1358	cellular component organization or biogenesis
C7M27_01955	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M27_01956	COG0195	Participates in both transcription termination and antitermination
C7M27_01957	COG0779	Required for maturation of 30S ribosomal subunits
C7M27_01958	COG2176	DNA-directed DNA polymerase activity
C7M27_01959	COG0442	prolyl-tRNA aminoacylation
C7M27_01960	COG0750	zinc metalloprotease
C7M27_01961	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7M27_01962	COG4589	Belongs to the CDS family
C7M27_01963	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M27_01964	COG0233	cytoplasmic translational termination
C7M27_01965	COG0528	UMP kinase activity
C7M27_01966	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7M27_01967	COG0052	Belongs to the universal ribosomal protein uS2 family
C7M27_01969	COG1191	sigma factor activity
C7M27_01970	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C7M27_01971	COG1776	CheC inhibitor of MCP methylation
C7M27_01972	COG0835	chemotaxis
C7M27_01973	COG2198	Histidine kinase
C7M27_01973	COG0643	Histidine kinase
C7M27_01974	COG2201	protein-glutamate methylesterase activity
C7M27_01975	COG0455	bacterial-type flagellum organization
C7M27_01976	COG1419	protein localization to endoplasmic reticulum
C7M27_01977	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M27_01978	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M27_01979	COG1684	flagellar biosynthetic protein fliR
C7M27_01980	COG1987	bacterial-type flagellum assembly
C7M27_01981	COG1338	Plays a role in the flagellum-specific transport system
C7M27_01982	COG3190	flagellar
C7M27_01983	COG2201	protein-glutamate methylesterase activity
C7M27_01984	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M27_01984	COG1776	CheC inhibitor of MCP methylation
C7M27_01985	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M27_01986	COG1580	Controls the rotational direction of flagella during chemotaxis
C7M27_01987	COG4786	Flagellar basal body rod
C7M27_01988	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7M27_01989	COG3144	bacterial-type flagellum assembly
C7M27_01990	COG3334	PFAM MgtE intracellular
C7M27_01991	COG2882	bacterial-type flagellum organization
C7M27_01992	COG1157	protein secretion by the type III secretion system
C7M27_01993	COG1317	bacterial-type flagellum organization
C7M27_01994	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M27_01995	COG1766	The M ring may be actively involved in energy transduction
C7M27_01996	COG1677	Flagellar hook-basal body complex protein FliE
C7M27_01997	COG1558	bacterial-type flagellum-dependent cell motility
C7M27_01998	COG1815	bacterial-type flagellum-dependent cell motility
C7M27_01999	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M27_02000	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7M27_02001	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7M27_02002	COG4974	Belongs to the 'phage' integrase family
C7M27_02003	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7M27_02004	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M27_02005	COG0758	DNA mediated transformation
C7M27_02006	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M27_02007	COG0045	succinate-CoA ligase (ADP-forming) activity
C7M27_02008	COG2257	FlhB HrpN YscU SpaS Family
C7M27_02010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M27_02011	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M27_02012	COG0335	large ribosomal subunit rRNA binding
C7M27_02013	COG0336	Belongs to the RNA methyltransferase TrmD family
C7M27_02014	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7M27_02016	COG1837	Belongs to the UPF0109 family
C7M27_02017	COG0228	four-way junction DNA binding
C7M27_02018	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M27_02019	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7M27_02021	COG0552	protein localization to endoplasmic reticulum
C7M27_02022	COG1196	nuclear chromosome segregation
C7M27_02023	COG0571	ribonuclease III activity
C7M27_02025	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_02026	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M27_02027	COG0416	fatty acid biosynthetic process
C7M27_02028	COG1349	DNA-binding transcription factor activity
C7M27_02028	COG2050	protein possibly involved in aromatic compounds catabolism
C7M27_02029	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M27_02030	COG1760	l-serine dehydratase
C7M27_02031	COG1760	l-serine dehydratase
C7M27_02032	COG1461	Dihydroxyacetone kinase
C7M27_02033	COG1302	Protein conserved in bacteria
C7M27_02034	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7M27_02035	COG1564	THIamine pyrophosphokinase
C7M27_02036	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M27_02037	COG1162	GTPase activity
C7M27_02038	COG0515	serine threonine protein kinase
C7M27_02038	COG2815	serine threonine protein kinase
C7M27_02039	COG0631	protein serine/threonine phosphatase activity
C7M27_02040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7M27_02041	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M27_02041	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M27_02042	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7M27_02043	COG0242	peptide deformylase activity
C7M27_02044	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M27_02045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M27_02046	COG1758	RNA polymerase activity
C7M27_02047	COG0194	GDP metabolic process
C7M27_02049	COG1561	YicC-like family, N-terminal region
C7M27_02050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M27_02051	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C7M27_02052	COG1648	precorrin-2 dehydrogenase activity
C7M27_02053	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7M27_02054	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M27_02055	COG0529	Catalyzes the synthesis of activated sulfate
C7M27_02056	COG2046	Belongs to the sulfate adenylyltransferase family
C7M27_02057	COG0306	phosphate transporter
C7M27_02058	COG0175	sulfate reduction
C7M27_02060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M27_02061	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M27_02062	COG0167	dihydroorotate dehydrogenase activity
C7M27_02063	COG0543	2 iron, 2 sulfur cluster binding
C7M27_02064	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M27_02065	COG0505	Belongs to the CarA family
C7M27_02066	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M27_02067	COG0540	Belongs to the ATCase OTCase family
C7M27_02068	COG2233	PERMEase
C7M27_02069	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M27_02070	COG0564	pseudouridine synthase activity
C7M27_02071	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7M27_02072	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M27_02073	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M27_02074	COG3599	regulation of cell shape
C7M27_02075	COG2302	S4 RNA-binding domain
C7M27_02076	COG0762	integral membrane protein
C7M27_02077	COG1799	cell septum assembly
C7M27_02078	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7M27_02080	COG1873	PFAM PRC-barrel domain
C7M27_02081	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M27_02082	COG1119	ATPase activity
C7M27_02083	COG1191	sigma factor activity
C7M27_02084	COG1191	sigma factor activity
C7M27_02086	COG1404	Belongs to the peptidase S8 family
C7M27_02086	COG4412	M6 family metalloprotease domain protein
C7M27_02087	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M27_02088	COG0849	cell division
C7M27_02089	COG3856	small basic protein
C7M27_02090	COG3879	Bacterial protein of unknown function (DUF881)
C7M27_02091	COG3879	Bacterial protein of unknown function (DUF881)
C7M27_02092	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M27_02093	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7M27_02094	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M27_02095	COG0772	Belongs to the SEDS family
C7M27_02096	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M27_02097	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M27_02098	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7M27_02099	COG0768	penicillin binding
C7M27_02101	COG4839	cell division protein FtsL
C7M27_02102	COG0275	rRNA processing
C7M27_02103	COG2001	Belongs to the MraZ family
C7M27_02104	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C7M27_02105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M27_02106	COG0454	-acetyltransferase
C7M27_02109	COG1399	metal-binding, possibly nucleic acid-binding protein
C7M27_02111	COG1323	Belongs to the UPF0348 family
C7M27_02112	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M27_02113	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M27_02114	COG3314	Sporulation integral membrane protein YlbJ
C7M27_02115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7M27_02116	COG0742	ribosomal rna small subunit methyltransferase
C7M27_02117	COG4471	UPF0298 protein
C7M27_02118	COG3679	Belongs to the UPF0342 family
C7M27_02121	COG2340	Cysteine-rich secretory protein family
C7M27_02122	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C7M27_02124	COG3336	cytochrome c oxidase
C7M27_02125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M27_02126	COG1845	cytochrome c oxidase, subunit III
C7M27_02127	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M27_02128	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M27_02128	COG2010	Cytochrome c
C7M27_02129	COG0109	protoheme IX farnesyltransferase activity
C7M27_02130	COG1612	heme a metabolic process
C7M27_02131	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M27_02132	COG0772	Belongs to the SEDS family
C7M27_02133	COG4838	Belongs to the UPF0358 family
C7M27_02134	COG2066	Belongs to the glutaminase family
C7M27_02135	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M27_02136	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7M27_02138	COG4896	Protein conserved in bacteria
C7M27_02144	COG1595	DNA-templated transcription, initiation
C7M27_02148	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7M27_02150	COG0483	inositol monophosphate 1-phosphatase activity
C7M27_02152	COG4493	Belongs to the UPF0637 family
C7M27_02153	COG4476	Belongs to the UPF0223 family
C7M27_02154	COG1982	Orn Lys Arg decarboxylase major
C7M27_02155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_02156	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M27_02157	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M27_02158	COG0022	dehydrogenase e1 component
C7M27_02159	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M27_02160	COG0497	DNA recombination
C7M27_02162	COG0242	peptide deformylase activity
C7M27_02163	COG0561	phosphatase activity
C7M27_02165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M27_02166	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M27_02167	COG0569	domain protein
C7M27_02168	COG2105	PFAM AIG2 family protein
C7M27_02168	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C7M27_02169	COG3852	Histidine kinase
C7M27_02170	COG2002	toxin-antitoxin pair type II binding
C7M27_02171	COG1077	Cell shape determining protein MreB Mrl
C7M27_02173	COG2309	aminopeptidase activity
C7M27_02174	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M27_02175	COG0488	(ABC) transporter
C7M27_02177	COG0681	Belongs to the peptidase S26 family
C7M27_02178	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M27_02178	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M27_02178	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M27_02179	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M27_02180	COG1349	DNA-binding transcription factor activity
C7M27_02181	COG0577	efflux transmembrane transporter activity
C7M27_02182	COG1136	(ABC) transporter
C7M27_02183	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M27_02185	COG1132	(ABC) transporter
C7M27_02186	COG1132	(ABC) transporter
C7M27_02187	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7M27_02188	COG0314	molybdopterin synthase activity
C7M27_02189	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M27_02190	COG0303	'Molybdopterin
C7M27_02191	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M27_02192	COG0746	molybdenum cofactor guanylyltransferase activity
C7M27_02195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_02196	COG0450	alkyl hydroperoxide reductase
C7M27_02197	COG0668	transmembrane transport
C7M27_02199	COG1473	amidohydrolase
C7M27_02200	COG2171	N-acyltransferase activity
C7M27_02201	COG0716	FMN binding
C7M27_02203	COG0716	FMN binding
C7M27_02204	COG0583	DNA-binding transcription factor activity
C7M27_02205	COG0517	IMP dehydrogenase activity
C7M27_02207	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C7M27_02208	COG4703	Protein of unknown function (DUF1797)
C7M27_02209	COG2200	EAL domain
C7M27_02210	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_02211	COG1408	metallophosphoesterase
C7M27_02212	COG1376	ErfK ybiS ycfS ynhG family protein
C7M27_02213	COG2814	Major facilitator Superfamily
C7M27_02215	COG0784	Response regulator, receiver
C7M27_02215	COG0835	chemotaxis
C7M27_02217	COG0436	Aminotransferase
C7M27_02218	COG4191	Histidine kinase
C7M27_02219	COG0768	penicillin binding
C7M27_02220	COG2340	Cysteine-rich secretory protein family
C7M27_02221	COG4257	antibiotic catabolic process
C7M27_02222	COG2084	Dehydrogenase
C7M27_02223	COG0840	transmembrane signaling receptor activity
C7M27_02224	COG0456	acetyltransferase
C7M27_02225	COG0456	acetyltransferase
C7M27_02226	COG1533	DNA photolyase activity
C7M27_02228	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M27_02229	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M27_02230	COG1263	PTS System
C7M27_02230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M27_02230	COG2190	(PTS) system
C7M27_02231	COG3711	transcriptional antiterminator
C7M27_02233	COG1609	Transcriptional regulator
C7M27_02235	COG0006	proline dipeptidase activity
C7M27_02236	COG2217	Heavy metal translocating P-type atpase
C7M27_02237	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_02238	COG2244	polysaccharide biosynthetic process
C7M27_02239	COG3773	Cell wall hydrolase
C7M27_02241	COG4873	Protein conserved in bacteria
C7M27_02243	COG3858	chitin binding
C7M27_02244	COG1388	LysM domain
C7M27_02245	COG1388	LysM domain
C7M27_02245	COG4641	Protein conserved in bacteria
C7M27_02246	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_02247	COG1733	regulation of RNA biosynthetic process
C7M27_02248	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7M27_02249	COG0602	queuosine metabolic process
C7M27_02250	COG0720	synthase
C7M27_02251	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7M27_02252	COG3949	Membrane
C7M27_02253	COG0542	response to heat
C7M27_02254	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M27_02255	COG1360	Flagellar Motor Protein
C7M27_02256	COG1846	Transcriptional regulator
C7M27_02257	COG3852	Histidine kinase
C7M27_02260	COG3339	Conserved Protein
C7M27_02261	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C7M27_02262	COG0235	Class ii aldolase
C7M27_02263	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
C7M27_02264	COG1850	ribulose-bisphosphate carboxylase activity
C7M27_02265	COG0436	Aminotransferase
C7M27_02266	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M27_02267	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
C7M27_02268	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C7M27_02270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M27_02271	COG5002	protein histidine kinase activity
C7M27_02272	COG3594	Acyltransferase
C7M27_02275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M27_02276	COG0501	Belongs to the peptidase M48B family
C7M27_02280	COG1191	sigma factor activity
C7M27_02281	COG0861	Integral membrane protein TerC family
C7M27_02282	COG0586	Pfam SNARE associated Golgi protein
C7M27_02283	COG3300	MHYT domain
C7M27_02283	COG5001	Diguanylate cyclase
C7M27_02284	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C7M27_02285	COG3285	dna ligase
C7M27_02285	COG1793	dna ligase
C7M27_02286	COG0463	Glycosyl transferase, family 2
C7M27_02288	COG1408	metallophosphoesterase
C7M27_02289	COG0726	polysaccharide deacetylase
C7M27_02290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M27_02291	COG1846	Transcriptional regulator
C7M27_02294	COG0789	Transcriptional regulator
C7M27_02295	COG2239	Acts as a magnesium transporter
C7M27_02298	COG3212	peptidase
C7M27_02299	COG3212	peptidase
C7M27_02300	COG3850	Histidine kinase
C7M27_02300	COG5002	protein histidine kinase activity
C7M27_02301	COG0745	RESPONSE REGULATOR receiver
C7M27_02303	COG4721	ABC-type cobalt transport system, permease component
C7M27_02304	COG1122	ATPase activity
C7M27_02305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M27_02306	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M27_02307	COG1404	Belongs to the peptidase S8 family
C7M27_02308	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M27_02309	COG0590	tRNA wobble adenosine to inosine editing
C7M27_02310	COG1764	response to oxidative stress
C7M27_02311	COG1846	Transcriptional regulator
C7M27_02312	COG1764	response to oxidative stress
C7M27_02313	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M27_02314	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M27_02315	COG0788	formyltetrahydrofolate deformylase activity
C7M27_02316	COG2076	Multidrug Resistance protein
C7M27_02317	COG2076	Multidrug Resistance protein
C7M27_02318	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M27_02319	COG2318	DinB family
C7M27_02320	COG2323	membrane
C7M27_02322	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M27_02322	COG1017	nitric oxide dioxygenase activity
C7M27_02323	COG1607	acyl-coa hydrolase
C7M27_02324	COG1834	amidinotransferase
C7M27_02325	COG2706	6-phosphogluconolactonase activity
C7M27_02326	COG4608	Belongs to the ABC transporter superfamily
C7M27_02327	COG0791	NLP P60 protein
C7M27_02328	COG4948	Mandelate Racemase Muconate Lactonizing
C7M27_02329	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M27_02331	COG4166	transmembrane transport
C7M27_02332	COG0444	Belongs to the ABC transporter superfamily
C7M27_02333	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M27_02334	COG0601	transmembrane transport
C7M27_02335	COG2362	D-Aminopeptidase
C7M27_02336	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M27_02337	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M27_02339	COG0463	Glycosyl transferase, family 2
C7M27_02340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M27_02341	COG0346	lactoylglutathione lyase activity
C7M27_02342	COG0531	amino acid
C7M27_02343	COG1392	Phosphate transport regulator
C7M27_02344	COG0306	phosphate transporter
C7M27_02347	COG3409	Peptidoglycan-binding domain 1 protein
C7M27_02347	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M27_02354	COG3778	Protein conserved in bacteria
C7M27_02355	COG3299	homolog of phage Mu protein gp47
C7M27_02356	COG3628	GPW Gp25 family protein
C7M27_02358	COG4193	domain, Protein
C7M27_02359	COG1652	LysM domain
C7M27_02360	COG3953	SLT domain
C7M27_02360	COG5412	phage tail tape measure protein
C7M27_02368	COG4653	Phage capsid family
C7M27_02369	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M27_02370	COG5518	Phage portal protein
C7M27_02371	COG1783	phage Terminase large subunit
C7M27_02372	COG5484	DNA packaging
C7M27_02372	COG3728	DNA packaging
C7M27_02373	COG1595	DNA-templated transcription, initiation
C7M27_02377	COG1484	DNA-dependent DNA replication
C7M27_02378	COG1522	sequence-specific DNA binding
C7M27_02380	COG1396	sequence-specific DNA binding
C7M27_02381	COG2856	Zn peptidase
C7M27_02382	COG3546	catalase activity
C7M27_02383	COG4195	phage-related replication protein
C7M27_02385	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M27_02385	COG3409	Peptidoglycan-binding domain 1 protein
C7M27_02385	COG1388	LysM domain
C7M27_02386	COG2350	Protein conserved in bacteria
C7M27_02388	COG0457	Tetratricopeptide repeat
C7M27_02389	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M27_02390	COG2318	DinB family
C7M27_02391	COG0730	response to heat
C7M27_02392	COG2721	sulfolactate sulfo-lyase activity
C7M27_02393	COG0246	Mannitol dehydrogenase
C7M27_02394	COG1609	Transcriptional regulator
C7M27_02395	COG2271	Major facilitator Superfamily
C7M27_02396	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_02397	COG1312	Catalyzes the dehydration of D-mannonate
C7M27_02398	COG1063	alcohol dehydrogenase
C7M27_02399	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M27_02400	COG2211	Major facilitator Superfamily
C7M27_02401	COG1904	glucuronate isomerase
C7M27_02402	COG1252	NADH dehydrogenase
C7M27_02404	COG4297	protein containing double-stranded beta helix domain
C7M27_02405	COG0697	spore germination
C7M27_02406	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M27_02407	COG0390	transport system, permease component
C7M27_02408	COG1587	Uroporphyrinogen-III synthase
C7M27_02410	COG1819	glycosyl
C7M27_02411	COG2124	cytochrome p450
C7M27_02413	COG1051	belongs to the nudix hydrolase family
C7M27_02415	COG2427	Protein of unknown function (DUF1641)
C7M27_02416	COG3383	formate dehydrogenase (NAD+) activity
C7M27_02418	COG2205	protein histidine kinase activity
C7M27_02419	COG5504	Zn-dependent protease
C7M27_02422	COG0726	polysaccharide deacetylase
C7M27_02424	COG0109	protoheme IX farnesyltransferase activity
C7M27_02427	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M27_02429	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M27_02431	COG1482	cell wall glycoprotein biosynthetic process
C7M27_02432	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M27_02432	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M27_02432	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M27_02433	COG3711	transcriptional antiterminator
C7M27_02433	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M27_02435	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_02436	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M27_02437	COG0457	Tetratricopeptide repeat
C7M27_02442	COG5444	nuclease activity
C7M27_02448	COG5444	nuclease activity
C7M27_02450	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M27_02450	COG3409	Peptidoglycan-binding domain 1 protein
C7M27_02451	COG4824	toxin secretion phage lysis holin
C7M27_02473	COG1783	phage Terminase large subunit
C7M27_02474	COG5484	DNA packaging
C7M27_02479	COG1595	DNA-templated transcription, initiation
C7M27_02489	COG1484	DNA-dependent DNA replication
C7M27_02500	COG1396	sequence-specific DNA binding
C7M27_02503	COG2856	Zn peptidase
C7M27_02504	COG4974	Belongs to the 'phage' integrase family
C7M27_02506	COG5505	Protein of unknown function (DUF819)
C7M27_02507	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M27_02508	COG0626	cystathionine gamma-synthase activity
C7M27_02509	COG0626	cystathionine gamma-synthase activity
C7M27_02510	COG2382	esterase
C7M27_02511	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M27_02512	COG2153	protein acetylation
C7M27_02514	COG0210	DNA helicase
C7M27_02525	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M27_02526	COG0351	phosphomethylpyrimidine kinase
C7M27_02527	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M27_02528	COG2022	thiamine diphosphate biosynthetic process
C7M27_02529	COG2104	thiamine diphosphate biosynthetic process
C7M27_02530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M27_02531	COG0352	thiamine-phosphate diphosphorylase activity
C7M27_02532	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7M27_02533	COG0569	domain protein
C7M27_02533	COG0475	glutathione-regulated potassium exporter activity
C7M27_02534	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7M27_02535	COG0564	pseudouridine synthase activity
C7M27_02536	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M27_02537	COG2357	RelA SpoT domain protein
C7M27_02539	COG4116	CYTH
C7M27_02540	COG0741	lytic transglycosylase activity
C7M27_02541	COG2346	COG2346, Truncated hemoglobins
C7M27_02544	COG1164	Oligoendopeptidase f
C7M27_02545	COG4469	Competence protein
C7M27_02546	COG4862	establishment of competence for transformation
C7M27_02547	COG0861	Integral membrane protein TerC family
C7M27_02548	COG1393	Belongs to the ArsC family
C7M27_02549	COG0456	acetyltransferase
C7M27_02550	COG2814	Major facilitator Superfamily
C7M27_02551	COG4608	Belongs to the ABC transporter superfamily
C7M27_02552	COG0444	Belongs to the ABC transporter superfamily
C7M27_02553	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M27_02554	COG0601	transmembrane transport
C7M27_02555	COG4166	transmembrane transport
C7M27_02556	COG0180	Tryptophanyl-tRNA synthetase
C7M27_02558	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M27_02559	COG0601	transmembrane transport
C7M27_02561	COG4608	Belongs to the ABC transporter superfamily
C7M27_02562	COG0444	Belongs to the ABC transporter superfamily
C7M27_02563	COG5504	Zn-dependent protease
C7M27_02564	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M27_02565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M27_02568	COG1744	ABC transporter substrate-binding protein PnrA-like
C7M27_02570	COG2267	carboxylic ester hydrolase activity
C7M27_02573	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M27_02574	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M27_02575	COG0505	Belongs to the CarA family
C7M27_02576	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M27_02578	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7M27_02579	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7M27_02580	COG2271	Major facilitator Superfamily
C7M27_02581	COG0277	FAD linked oxidase domain protein
C7M27_02583	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M27_02584	COG1073	alpha beta
C7M27_02585	COG0561	phosphatase activity
C7M27_02589	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M27_02590	COG1307	EDD domain protein, DegV family
C7M27_02591	COG3227	Zinc metalloprotease (Elastase)
C7M27_02594	COG1695	Transcriptional regulator
C7M27_02598	COG2996	Protein conserved in bacteria
C7M27_02599	COG1666	GTP binding
C7M27_02600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M27_02600	COG0646	methionine synthase
C7M27_02601	COG2153	protein acetylation
C7M27_02602	COG0454	-acetyltransferase
C7M27_02603	COG2814	Major facilitator Superfamily
C7M27_02604	COG4948	Mandelate Racemase Muconate Lactonizing
C7M27_02605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M27_02606	COG1809	phosphosulfolactate synthase activity
C7M27_02607	COG2045	Belongs to the ComB family
C7M27_02608	COG0175	sulfate reduction
C7M27_02609	COG2046	Belongs to the sulfate adenylyltransferase family
C7M27_02610	COG0529	Catalyzes the synthesis of activated sulfate
C7M27_02611	COG2267	carboxylic ester hydrolase activity
C7M27_02612	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M27_02613	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M27_02629	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M27_02630	COG1279	arginine transmembrane transporter activity
C7M27_02631	COG2318	DinB family
C7M27_02632	COG0673	inositol 2-dehydrogenase activity
C7M27_02633	COG1609	Transcriptional regulator
C7M27_02634	COG2207	Transcriptional regulator
C7M27_02634	COG1917	Cupin 2, conserved barrel domain protein
C7M27_02635	COG0534	Mate efflux family protein
C7M27_02636	COG1562	ergosterol biosynthetic process
C7M27_02637	COG2318	DinB family
C7M27_02638	COG0367	asparagine synthase
C7M27_02640	COG1404	Belongs to the peptidase S8 family
C7M27_02642	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7M27_02643	COG5337	Spore coat protein CotH
C7M27_02651	COG1403	HNH endonuclease
C7M27_02652	COG0419	ATPase involved in DNA repair
C7M27_02653	COG0420	3'-5' exonuclease activity
C7M27_02654	COG1074	ATP-dependent DNA helicase activity
C7M27_02655	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7M27_02656	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M27_02658	COG4533	DNA binding
C7M27_02659	COG2814	Major facilitator Superfamily
C7M27_02659	COG0477	Major facilitator Superfamily
C7M27_02660	COG3180	Ammonia monooxygenase
C7M27_02661	COG1609	Transcriptional regulator
C7M27_02662	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M27_02663	COG0561	phosphatase activity
C7M27_02664	COG0673	inositol 2-dehydrogenase activity
C7M27_02665	COG0738	Major facilitator superfamily
C7M27_02668	COG1846	Transcriptional regulator
C7M27_02669	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M27_02670	COG0681	Belongs to the peptidase S26 family
C7M27_02671	COG0398	Pfam SNARE associated Golgi protein
C7M27_02674	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M27_02676	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_02677	COG4903	ComK protein
C7M27_02679	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_02680	COG0723	plastoquinol--plastocyanin reductase activity
C7M27_02680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M27_02681	COG0840	transmembrane signaling receptor activity
C7M27_02682	COG1268	BioY protein
C7M27_02683	COG0318	PFAM AMP-dependent synthetase and ligase
C7M27_02684	COG0183	Belongs to the thiolase family
C7M27_02685	COG0406	alpha-ribazole phosphatase activity
C7M27_02686	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M27_02687	COG0604	alcohol dehydrogenase
C7M27_02688	COG0456	acetyltransferase
C7M27_02690	COG0501	Belongs to the peptidase M48B family
C7M27_02692	COG0318	PFAM AMP-dependent synthetase and ligase
C7M27_02693	COG0702	epimerase
C7M27_02694	COG0095	Lipoate-protein ligase
C7M27_02695	COG1234	tRNA 3'-trailer cleavage
C7M27_02696	COG1301	dicarboxylic acid transport
C7M27_02697	COG4405	Protein conserved in bacteria
C7M27_02698	COG1363	Peptidase, m42
C7M27_02699	COG4377	Putative membrane peptidase family (DUF2324)
C7M27_02700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M27_02701	COG1511	domain protein
C7M27_02702	COG1309	transcriptional regulator
C7M27_02705	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7M27_02706	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M27_02707	COG2329	Antibiotic biosynthesis monooxygenase
C7M27_02709	COG3069	C4-dicarboxylate transmembrane transporter activity
C7M27_02710	COG1473	amidohydrolase
C7M27_02712	COG4473	ABC transporter
C7M27_02713	COG1131	(ABC) transporter
C7M27_02714	COG0537	adenosine 5'-monophosphoramidase activity
C7M27_02715	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M27_02718	COG4980	gas vesicle protein
C7M27_02719	COG1846	Transcriptional regulator
C7M27_02722	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M27_02724	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7M27_02725	COG4717	serine-type aminopeptidase activity
C7M27_02726	COG0420	3'-5' exonuclease activity
C7M27_02727	COG1668	transmembrane transport
C7M27_02728	COG4152	abc transporter atp-binding protein
C7M27_02730	COG1024	Enoyl-CoA hydratase
C7M27_02732	COG0490	domain, Protein
C7M27_02733	COG0475	glutathione-regulated potassium exporter activity
C7M27_02734	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M27_02735	COG0561	phosphatase activity
C7M27_02736	COG4335	DNA alkylation repair
C7M27_02737	COG3679	Belongs to the UPF0342 family
C7M27_02738	COG4399	Belongs to the UPF0754 family
C7M27_02739	COG0189	ligase activity
C7M27_02740	COG0189	ligase activity
C7M27_02743	COG0702	epimerase
C7M27_02744	COG1132	(ABC) transporter
C7M27_02745	COG1132	(ABC) transporter
C7M27_02746	COG0589	response to stress
C7M27_02747	COG1757	Na H antiporter
C7M27_02748	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M27_02749	COG0726	polysaccharide deacetylase
C7M27_02750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M27_02751	COG0668	transmembrane transport
C7M27_02753	COG0584	glycerophosphoryl diester phosphodiesterase
C7M27_02754	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M27_02755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M27_02756	COG1253	flavin adenine dinucleotide binding
C7M27_02757	COG0436	Aminotransferase
C7M27_02758	COG0789	Transcriptional regulator
C7M27_02759	COG1253	flavin adenine dinucleotide binding
C7M27_02760	COG0204	Acyl-transferase
C7M27_02761	COG0667	Aldo Keto reductase
C7M27_02762	COG1595	DNA-templated transcription, initiation
C7M27_02765	COG0456	acetyltransferase
C7M27_02766	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M27_02767	COG0733	neurotransmitter:sodium symporter activity
C7M27_02768	COG0531	amino acid
C7M27_02769	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_02770	COG0372	Belongs to the citrate synthase family
C7M27_02771	COG0583	DNA-binding transcription factor activity
C7M27_02772	COG0791	NLP P60 protein
C7M27_02772	COG1388	LysM domain
C7M27_02773	COG1785	Belongs to the alkaline phosphatase family
C7M27_02774	COG2719	SpoVR family
C7M27_02775	COG0668	transmembrane transport
C7M27_02776	COG1959	2 iron, 2 sulfur cluster binding
C7M27_02777	COG1388	LysM domain
C7M27_02777	COG0791	NLP P60 protein
C7M27_02780	COG0431	NADPH-dependent FMN reductase
C7M27_02781	COG2197	response regulator
C7M27_02782	COG2203	Gaf domain
C7M27_02782	COG4585	Histidine kinase
C7M27_02783	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M27_02784	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7M27_02785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M27_02786	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M27_02787	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7M27_02788	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M27_02789	COG3153	acetyltransferase
C7M27_02789	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M27_02790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M27_02791	COG0517	IMP dehydrogenase activity
C7M27_02793	COG0564	pseudouridine synthase activity
C7M27_02794	COG3764	Sortase (surface protein transpeptidase)
C7M27_02795	COG0737	Belongs to the 5'-nucleotidase family
C7M27_02795	COG1525	nuclease
C7M27_02795	COG4085	toxin activity
C7M27_02796	COG5577	PFAM Coat F domain
C7M27_02802	COG1823	symporter activity
C7M27_02803	COG3706	GGDEF domain
C7M27_02804	COG1464	Belongs to the NlpA lipoprotein family
C7M27_02805	COG1278	Cold shock
C7M27_02806	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M27_02807	COG1131	(ABC) transporter
C7M27_02808	COG1131	(ABC) transporter
C7M27_02809	COG1725	Transcriptional regulator
C7M27_02812	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M27_02813	COG2814	Major facilitator Superfamily
C7M27_02814	COG1566	PFAM secretion protein HlyD family protein
C7M27_02815	COG1846	Transcriptional regulator
C7M27_02816	COG2718	Belongs to the UPF0229 family
C7M27_02817	COG2766	serine protein kinase
C7M27_02818	COG1664	Polymer-forming cytoskeletal
C7M27_02819	COG1664	Polymer-forming cytoskeletal
C7M27_02820	COG0789	Transcriptional regulator
C7M27_02821	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M27_02823	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7M27_02824	COG3382	B3 4 domain protein
C7M27_02826	COG1476	TRANSCRIPTIONal
C7M27_02828	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M27_02830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M27_02831	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M27_02832	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M27_02833	COG1116	anion transmembrane transporter activity
C7M27_02834	COG0753	catalase activity
C7M27_02836	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7M27_02837	COG3340	Belongs to the peptidase S51 family
C7M27_02839	COG4326	sporulation control protein
C7M27_02861	COG0735	belongs to the Fur family
C7M27_02862	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7M27_02863	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M27_02864	COG4129	membrane
C7M27_02865	COG1132	(ABC) transporter
C7M27_02866	COG3557	Belongs to the UPF0374 family
C7M27_02869	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_02871	COG1194	a g-specific adenine glycosylase
C7M27_02872	COG1988	membrane-bound metal-dependent
C7M27_02873	COG4485	Bacterial membrane protein, YfhO
C7M27_02874	COG0463	Glycosyl transferase, family 2
C7M27_02875	COG0596	Alpha beta hydrolase
C7M27_02876	COG5658	integral membrane protein
C7M27_02877	COG3103	Sh3 type 3 domain protein
C7M27_02880	COG2814	Major facilitator Superfamily
C7M27_02883	COG2137	regulation of response to DNA damage stimulus
C7M27_02884	COG1090	epimerase
C7M27_02887	COG0778	Nitroreductase
C7M27_02888	COG0384	phenazine biosynthesis protein PhzF
C7M27_02889	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M27_02890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M27_02891	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M27_02892	COG0392	lysyltransferase activity
C7M27_02892	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7M27_02893	COG1846	Transcriptional regulator
C7M27_02894	COG2814	Major facilitator Superfamily
C7M27_02895	COG2318	DinB family
C7M27_02896	COG2814	Major facilitator Superfamily
C7M27_02897	COG1309	transcriptional regulator
C7M27_02898	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7M27_02899	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M27_02900	COG1695	Transcriptional regulator
C7M27_02901	COG0842	Transport permease protein
C7M27_02902	COG0842	Transport permease protein
C7M27_02902	COG1511	domain protein
C7M27_02903	COG1131	(ABC) transporter
C7M27_02904	COG2197	response regulator
C7M27_02905	COG4585	Histidine kinase
C7M27_02906	COG2514	catechol 2,3-dioxygenase activity
C7M27_02907	COG2259	Doxx family
C7M27_02908	COG1132	(ABC) transporter
C7M27_02909	COG1132	(ABC) transporter
C7M27_02910	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M27_02911	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M27_02911	COG1263	PTS System
C7M27_02912	COG1737	Transcriptional regulator
C7M27_02913	COG1486	melibiose metabolic process
C7M27_02914	COG4842	Belongs to the WXG100 family
C7M27_02918	COG1742	UPF0060 membrane protein
C7M27_02920	COG3284	Transcriptional regulator
C7M27_02921	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M27_02922	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M27_02923	COG0022	dehydrogenase e1 component
C7M27_02924	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M27_02926	COG4637	Psort location Cytoplasmic, score
C7M27_02927	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M27_02929	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M27_02930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M27_02931	COG0598	Magnesium transport protein CorA
C7M27_02932	COG2084	Dehydrogenase
C7M27_02933	COG0726	polysaccharide deacetylase
C7M27_02935	COG0535	radical SAM domain protein
C7M27_02936	COG0668	transmembrane transport
C7M27_02938	COG0387	Pfam Sodium calcium exchanger
C7M27_02939	COG0477	Major facilitator Superfamily
C7M27_02941	COG1295	ribonuclease BN
C7M27_02942	COG4980	gas vesicle protein
C7M27_02943	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M27_02944	COG4840	Belongs to the UPF0435 family
C7M27_02945	COG2814	Major facilitator Superfamily
C7M27_02946	COG0693	protein deglycase activity
C7M27_02947	COG0737	Belongs to the 5'-nucleotidase family
C7M27_02948	COG0778	Nitroreductase
C7M27_02949	COG2188	Transcriptional regulator
C7M27_02950	COG0366	Alpha amylase catalytic
C7M27_02951	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M27_02951	COG1263	PTS System
C7M27_02952	COG0697	spore germination
C7M27_02955	COG0531	amino acid
C7M27_02956	COG1115	amino acid carrier protein
C7M27_02958	COG1368	sulfuric ester hydrolase activity
C7M27_02959	COG1263	PTS System
C7M27_02959	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M27_02960	COG0024	Methionine aminopeptidase
C7M27_02964	COG2258	MOSC domain
C7M27_02965	COG1254	Belongs to the acylphosphatase family
C7M27_02966	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C7M27_02967	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M27_02968	COG2851	Citrate transporter
C7M27_02969	COG3181	Tripartite tricarboxylate transporter family receptor
C7M27_02970	COG4565	transcriptional regulatory protein
C7M27_02971	COG3290	protein histidine kinase activity
C7M27_02972	COG0471	metal ion transport
C7M27_02973	COG3866	Pectate lyase
C7M27_02976	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M27_02977	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M27_02978	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M27_02979	COG1120	ATPase activity
C7M27_02980	COG2130	NADP-dependent
C7M27_02981	COG0456	acetyltransferase
C7M27_02982	COG0513	Belongs to the DEAD box helicase family
C7M27_02983	COG0488	(ABC) transporter
C7M27_02987	COG1404	Belongs to the peptidase S8 family
C7M27_02988	COG2814	Major facilitator Superfamily
C7M27_02989	COG0789	Transcriptional regulator
C7M27_02991	COG0488	(ABC) transporter
C7M27_02992	COG0840	transmembrane signaling receptor activity
C7M27_02993	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_02994	COG0531	amino acid
C7M27_02995	COG1011	Hydrolase
C7M27_02996	COG2223	nitrite transmembrane transporter activity
C7M27_02997	COG1442	glycosyl transferase family 8
C7M27_02998	COG1216	Glycosyl transferase, family 2
C7M27_02999	COG1442	glycosyl transferase family 8
C7M27_03000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M27_03001	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7M27_03002	COG1368	sulfuric ester hydrolase activity
C7M27_03003	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M27_03003	COG2124	cytochrome p450
C7M27_03005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M27_03006	COG1846	Transcriptional regulator
C7M27_03007	COG0697	spore germination
C7M27_03009	COG0072	phenylalanine-tRNA ligase activity
C7M27_03011	COG0673	inositol 2-dehydrogenase activity
C7M27_03013	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M27_03018	COG0135	phosphoribosylanthranilate isomerase activity
C7M27_03019	COG0159	tryptophan synthase activity
C7M27_03020	COG0133	tryptophan synthase activity
C7M27_03021	COG0134	indole-3-glycerol-phosphate synthase activity
C7M27_03022	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M27_03023	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M27_03024	COG0670	Belongs to the BI1 family
C7M27_03025	COG5583	Uncharacterized small protein (DUF2292)
C7M27_03028	COG0346	lactoylglutathione lyase activity
C7M27_03029	COG2329	Antibiotic biosynthesis monooxygenase
C7M27_03030	COG2323	membrane
C7M27_03031	COG1486	melibiose metabolic process
C7M27_03032	COG0395	ABC-type sugar transport system, permease component
C7M27_03033	COG4209	transmembrane transport
C7M27_03034	COG1653	transport
C7M27_03036	COG1874	Beta-galactosidase
C7M27_03037	COG2755	lipolytic protein G-D-S-L family
C7M27_03038	COG3401	FG-GAP repeat protein
C7M27_03039	COG3401	FG-GAP repeat protein
C7M27_03040	COG5578	integral membrane protein
C7M27_03042	COG2755	lipolytic protein G-D-S-L family
C7M27_03043	COG2207	Transcriptional regulator
C7M27_03044	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M27_03045	COG0395	ABC-type sugar transport system, permease component
C7M27_03046	COG1175	transmembrane transport
C7M27_03047	COG1653	transport
C7M27_03048	COG2207	Transcriptional regulator
C7M27_03048	COG4753	response regulator
C7M27_03049	COG2972	Histidine kinase
C7M27_03050	COG5578	integral membrane protein
C7M27_03052	COG0454	-acetyltransferase
C7M27_03053	COG3546	catalase activity
C7M27_03056	COG0702	epimerase
C7M27_03057	COG3631	Ketosteroid isomerase-related protein
C7M27_03058	COG1309	transcriptional regulator
C7M27_03060	COG0217	transcriptional regulatory protein
C7M27_03062	COG0457	Tetratricopeptide repeat
C7M27_03063	COG3391	amine dehydrogenase activity
C7M27_03064	COG3586	endonuclease activity
C7M27_03066	COG5444	nuclease activity
C7M27_03070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M27_03071	COG1597	lipid kinase activity
C7M27_03072	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7M27_03073	COG1309	transcriptional regulator
C7M27_03074	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M27_03075	COG0154	amidase activity
C7M27_03076	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M27_03077	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M27_03078	COG1285	pathogenesis
C7M27_03079	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M27_03080	COG4851	CamS sex pheromone cAM373 precursor
C7M27_03081	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7M27_03082	COG0210	DNA helicase
C7M27_03083	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C7M27_03085	COG0069	glutamate synthase activity
C7M27_03086	COG4496	protein, YerC YecD
C7M27_03087	COG1470	cell adhesion involved in biofilm formation
C7M27_03088	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M27_03090	COG0531	amino acid
C7M27_03091	COG1522	sequence-specific DNA binding
C7M27_03092	COG0151	Belongs to the GarS family
C7M27_03093	COG0138	bifunctional purine biosynthesis protein purh
C7M27_03094	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M27_03095	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7M27_03096	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7M27_03097	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M27_03098	COG0047	phosphoribosylformylglycinamidine synthase activity
C7M27_03099	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M27_03100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M27_03101	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M27_03102	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M27_03103	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7M27_03105	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C7M27_03107	COG3064	Membrane
C7M27_03108	COG2252	PERMEase
C7M27_03111	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7M27_03111	COG0519	Catalyzes the synthesis of GMP from XMP
C7M27_03112	COG1305	Transglutaminase-like
C7M27_03113	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C7M27_03114	COG0714	Associated with various cellular activities
C7M27_03115	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M27_03116	COG1113	amino acid transport
C7M27_03117	COG2132	Multicopper oxidase
C7M27_03119	COG2267	carboxylic ester hydrolase activity
C7M27_03122	COG0823	Involved in the tonB-independent uptake of proteins
C7M27_03123	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7M27_03124	COG1063	alcohol dehydrogenase
C7M27_03125	COG2814	Major facilitator Superfamily
C7M27_03127	COG4260	virion core protein, lumpy skin disease virus
C7M27_03128	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7M27_03129	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M27_03130	COG1842	Phage shock protein A
C7M27_03131	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M27_03132	COG2211	Major facilitator Superfamily
C7M27_03133	COG1063	alcohol dehydrogenase
C7M27_03134	COG0457	Tetratricopeptide repeat
C7M27_03135	COG1073	alpha beta
C7M27_03136	COG0459	protein refolding
C7M27_03138	COG1266	CAAX protease self-immunity
C7M27_03140	COG0805	protein transport
C7M27_03141	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M27_03142	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7M27_03143	COG0315	cyclic pyranopterin monophosphate synthase activity
C7M27_03144	COG0488	(ABC) transporter
C7M27_03145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M27_03146	COG0456	acetyltransferase
C7M27_03147	COG1214	PFAM Peptidase M22, glycoprotease
C7M27_03148	COG0802	atpase or kinase
C7M27_03149	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7M27_03158	COG4124	Belongs to the glycosyl hydrolase 26 family
C7M27_03159	COG1482	cell wall glycoprotein biosynthetic process
C7M27_03160	COG1940	carbohydrate kinase activity
C7M27_03161	COG2188	Transcriptional regulator
C7M27_03162	COG2723	6-phospho-beta-galactosidase activity
C7M27_03163	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M27_03164	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M27_03165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M27_03166	COG2814	Major facilitator Superfamily
C7M27_03167	COG1388	LysM domain
C7M27_03168	COG1078	dGTPase activity
C7M27_03169	COG0454	-acetyltransferase
C7M27_03171	COG5646	InterPro IPR014922
C7M27_03172	COG1785	Belongs to the alkaline phosphatase family
C7M27_03174	COG1819	glycosyl
C7M27_03175	COG1388	LysM domain
C7M27_03175	COG3858	chitin binding
C7M27_03176	COG1802	Transcriptional regulator
C7M27_03177	COG0730	response to heat
C7M27_03178	COG2814	Major facilitator Superfamily
C7M27_03179	COG1846	Transcriptional regulator
C7M27_03180	COG0778	Nitroreductase
C7M27_03181	COG2409	Drug exporters of the RND superfamily
C7M27_03181	COG1033	growth of symbiont in host cell
C7M27_03182	COG1846	Transcriptional regulator
C7M27_03183	COG2318	DinB family
C7M27_03184	COG1113	amino acid transport
C7M27_03186	COG0456	acetyltransferase
C7M27_03188	COG1309	transcriptional regulator
C7M27_03191	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M27_03192	COG2323	membrane
C7M27_03193	COG2323	membrane
C7M27_03197	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_03198	COG2259	Doxx family
C7M27_03199	COG0346	lactoylglutathione lyase activity
C7M27_03200	COG0778	Nitroreductase
C7M27_03201	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M27_03202	COG0789	Transcriptional regulator
C7M27_03202	COG4978	Transcriptional regulator
C7M27_03203	COG1811	Na channel or pump
C7M27_03204	COG0596	Alpha beta hydrolase
C7M27_03205	COG2409	Drug exporters of the RND superfamily
C7M27_03206	COG2197	response regulator
C7M27_03207	COG4585	Histidine kinase
C7M27_03209	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M27_03210	COG0640	Transcriptional regulator
C7M27_03211	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M27_03212	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M27_03213	COG0697	spore germination
C7M27_03214	COG0745	RESPONSE REGULATOR receiver
C7M27_03215	COG5002	protein histidine kinase activity
C7M27_03218	COG1316	TRANSCRIPTIONal
C7M27_03219	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M27_03220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M27_03221	COG0640	Transcriptional regulator
C7M27_03222	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M27_03223	COG1733	regulation of RNA biosynthetic process
C7M27_03224	COG3545	Serine hydrolase
C7M27_03225	COG2030	dehydratase
C7M27_03226	COG2030	dehydratase
C7M27_03227	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M27_03228	COG0697	spore germination
C7M27_03230	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C7M27_03232	COG0477	Major facilitator Superfamily
C7M27_03233	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M27_03234	COG3708	Transcriptional regulator
C7M27_03234	COG2207	Transcriptional regulator
C7M27_03235	COG0697	spore germination
C7M27_03236	COG1917	Cupin 2, conserved barrel domain protein
C7M27_03236	COG2207	Transcriptional regulator
C7M27_03237	COG0697	spore germination
C7M27_03238	COG1329	Transcriptional regulator
C7M27_03239	COG1278	Cold shock
C7M27_03240	COG0693	protein deglycase activity
C7M27_03245	COG5444	nuclease activity
C7M27_03248	COG2814	Major facilitator Superfamily
C7M27_03249	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7M27_03250	COG1335	isochorismatase
C7M27_03251	COG1522	sequence-specific DNA binding
C7M27_03252	COG1522	sequence-specific DNA binding
C7M27_03253	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M27_03261	COG3091	SprT-like family
C7M27_03262	COG2183	response to ionizing radiation
C7M27_03263	COG1846	Transcriptional regulator
C7M27_03264	COG1673	EVE domain
C7M27_03268	COG2208	phosphoserine phosphatase activity
C7M27_03269	COG1191	sigma factor activity
C7M27_03270	COG2172	sigma factor antagonist activity
C7M27_03271	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M27_03272	COG2208	phosphoserine phosphatase activity
C7M27_03273	COG2172	sigma factor antagonist activity
C7M27_03274	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M27_03275	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M27_03276	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M27_03277	COG0864	Transcriptional regulator
C7M27_03278	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M27_03279	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7M27_03280	COG0736	holo-[acyl-carrier-protein] synthase activity
C7M27_03281	COG0705	Rhomboid family
C7M27_03282	COG3428	Bacterial PH domain
C7M27_03283	COG3402	PFAM membrane-flanked domain
C7M27_03284	COG0513	Belongs to the DEAD box helicase family
C7M27_03285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M27_03286	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M27_03287	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M27_03288	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M27_03291	COG1960	acyl-CoA dehydrogenase activity
C7M27_03293	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M27_03294	COG1131	(ABC) transporter
C7M27_03295	COG0628	permease
C7M27_03296	COG1301	dicarboxylic acid transport
C7M27_03297	COG4565	transcriptional regulatory protein
C7M27_03298	COG3290	protein histidine kinase activity
C7M27_03299	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7M27_03300	COG3546	catalase activity
C7M27_03301	COG2329	Antibiotic biosynthesis monooxygenase
C7M27_03302	COG0662	Cupin 2, conserved barrel domain protein
C7M27_03303	COG3729	General stress protein
C7M27_03304	COG2217	Heavy metal translocating P-type atpase
C7M27_03305	COG4876	unkown
C7M27_03306	COG2261	transglycosylase associated protein
C7M27_03307	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M27_03309	COG0028	Belongs to the TPP enzyme family
C7M27_03310	COG0494	nUDIX hydrolase
C7M27_03311	COG0531	amino acid
C7M27_03313	COG1215	transferase activity, transferring glycosyl groups
C7M27_03314	COG5298	Protein conserved in bacteria
C7M27_03315	COG3706	GGDEF domain
C7M27_03316	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C7M27_03317	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M27_03317	COG0551	DNA topoisomerase type I activity
C7M27_03318	COG1522	sequence-specific DNA binding
C7M27_03319	COG2814	Major facilitator Superfamily
C7M27_03321	COG3871	stress protein (general stress protein 26)
C7M27_03322	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M27_03323	COG1917	Cupin 2, conserved barrel domain protein
C7M27_03324	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_03325	COG2226	methyltransferase
C7M27_03326	COG0318	PFAM AMP-dependent synthetase and ligase
C7M27_03327	COG3711	transcriptional antiterminator
C7M27_03328	COG4989	oxidoreductase activity
C7M27_03329	COG0768	penicillin binding
C7M27_03330	COG2329	Antibiotic biosynthesis monooxygenase
C7M27_03332	COG2755	lipolytic protein G-D-S-L family
C7M27_03333	COG1414	Transcriptional regulator
C7M27_03334	COG1984	allophanate hydrolase subunit 2
C7M27_03335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7M27_03336	COG4336	lyase activity
C7M27_03337	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M27_03338	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C7M27_03339	COG0561	phosphatase activity
C7M27_03341	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M27_03342	COG0412	Dienelactone hydrolase
C7M27_03343	COG0681	Belongs to the peptidase S26 family
C7M27_03345	COG0473	3-isopropylmalate dehydrogenase activity
C7M27_03346	COG0246	Mannitol dehydrogenase
C7M27_03347	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M27_03348	COG2213	PTS system mannitol-specific
C7M27_03350	COG1349	DNA-binding transcription factor activity
C7M27_03351	COG1276	copper resistance
C7M27_03351	COG2372	response to copper ion
C7M27_03352	COG4549	nuclear export factor GLE1
C7M27_03353	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_03354	COG4975	Glucose uptake
C7M27_03355	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_03356	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M27_03357	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M27_03358	COG0640	Transcriptional regulator
C7M27_03359	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M27_03360	COG0778	Nitroreductase
C7M27_03361	COG1309	transcriptional regulator
C7M27_03362	COG2814	Major facilitator Superfamily
C7M27_03363	COG4607	ABC-type enterochelin transport system periplasmic component
C7M27_03364	COG4604	ABC transporter, ATP-binding protein
C7M27_03365	COG4605	iron ion homeostasis
C7M27_03366	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M27_03367	COG0527	aspartate kinase activity
C7M27_03370	COG0457	Tetratricopeptide repeat
C7M27_03371	COG5002	protein histidine kinase activity
C7M27_03371	COG3850	Histidine kinase
C7M27_03372	COG0745	RESPONSE REGULATOR receiver
C7M27_03373	COG0577	efflux transmembrane transporter activity
C7M27_03374	COG1136	(ABC) transporter
C7M27_03375	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M27_03377	COG0697	spore germination
C7M27_03379	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M27_03380	COG3104	oligopeptide transport
C7M27_03381	COG0596	Alpha beta hydrolase
C7M27_03384	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M27_03385	COG0163	prenyltransferase activity
C7M27_03386	COG0583	DNA-binding transcription factor activity
C7M27_03387	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M27_03388	COG0765	amino acid transport
C7M27_03389	COG1126	abc transporter atp-binding protein
C7M27_03390	COG2364	Membrane
C7M27_03392	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M27_03393	COG0697	spore germination
C7M27_03395	COG2814	Major facilitator Superfamily
C7M27_03396	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7M27_03397	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_03398	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_03399	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_03400	COG1733	regulation of RNA biosynthetic process
C7M27_03401	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7M27_03402	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M27_03403	COG0840	transmembrane signaling receptor activity
C7M27_03403	COG3290	protein histidine kinase activity
C7M27_03404	COG3209	COG3209 Rhs family protein
C7M27_03406	COG2723	6-phospho-beta-galactosidase activity
C7M27_03407	COG3842	ATPase activity
C7M27_03409	COG1846	Transcriptional regulator
C7M27_03411	COG1714	RDD family
C7M27_03413	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M27_03414	COG0765	amino acid transport
C7M27_03415	COG0523	cobalamin synthesis protein
C7M27_03416	COG1376	ErfK ybiS ycfS ynhG family protein
C7M27_03417	COG1469	GTP cyclohydrolase I activity
C7M27_03418	COG2223	nitrite transmembrane transporter activity
C7M27_03419	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M27_03420	COG0243	molybdopterin cofactor binding
C7M27_03421	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M27_03422	COG2146	nitrite reductase [NAD(P)H] activity
C7M27_03423	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M27_03423	COG1587	Uroporphyrinogen-III synthase
C7M27_03424	COG0492	ferredoxin-NADP+ reductase activity
C7M27_03425	COG2267	carboxylic ester hydrolase activity
C7M27_03426	COG0701	Predicted permease
C7M27_03427	COG3689	TIGRFAM TIGR03943 family protein
C7M27_03431	COG2508	Transcriptional regulator
C7M27_03432	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M27_03433	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_03434	COG0506	proline dehydrogenase activity
C7M27_03435	COG3541	Predicted nucleotidyltransferase
C7M27_03436	COG3458	cephalosporin-C deacetylase activity
C7M27_03437	COG0583	DNA-binding transcription factor activity
C7M27_03438	COG2226	methyltransferase
C7M27_03439	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M27_03440	COG1660	Displays ATPase and GTPase activities
C7M27_03441	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7M27_03442	COG3665	Urea carboxylase-associated protein
C7M27_03443	COG1113	amino acid transport
C7M27_03444	COG3403	YqcI/YcgG family
C7M27_03445	COG1280	lysine exporter protein (LysE YggA)
C7M27_03446	COG1846	Transcriptional regulator
C7M27_03447	COG2814	Major facilitator Superfamily
C7M27_03448	COG1620	l-lactate permease
C7M27_03449	COG0039	L-malate dehydrogenase activity
C7M27_03450	COG0366	Alpha amylase catalytic
C7M27_03452	COG1288	antiporter activity
C7M27_03453	COG1473	amidohydrolase
C7M27_03454	COG2113	Glycine betaine
C7M27_03455	COG4176	ABC-type proline glycine betaine transport system permease component
C7M27_03456	COG0517	IMP dehydrogenase activity
C7M27_03456	COG4175	Glycine betaine
C7M27_03457	COG0640	Transcriptional regulator
C7M27_03458	COG2814	Major facilitator Superfamily
C7M27_03459	COG0477	Major facilitator Superfamily
C7M27_03460	COG3853	Toxic anion resistance protein (TelA)
C7M27_03462	COG0861	Integral membrane protein TerC family
C7M27_03463	COG2310	stress, protein
C7M27_03464	COG2310	stress, protein
C7M27_03465	COG2310	stress, protein
C7M27_03466	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M27_03467	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M27_03468	COG1121	(ABC) transporter
C7M27_03469	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M27_03470	COG0366	Alpha amylase catalytic
C7M27_03471	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_03472	COG0457	Tetratricopeptide repeat
C7M27_03473	COG1876	peptidase activity
C7M27_03474	COG1595	DNA-templated transcription, initiation
C7M27_03475	COG1595	DNA-templated transcription, initiation
C7M27_03477	COG0667	Aldo Keto reductase
C7M27_03478	COG1668	transmembrane transport
C7M27_03479	COG4555	ABC transporter
C7M27_03480	COG3279	Response regulator of the LytR AlgR family
C7M27_03481	COG3290	protein histidine kinase activity
C7M27_03482	COG1405	negative regulation of cell septum assembly
C7M27_03482	COG3012	SEC-C Motif Domain Protein
C7M27_03483	COG1714	RDD family
C7M27_03484	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M27_03485	COG0252	asparaginase activity
C7M27_03486	COG1309	transcriptional regulator
C7M27_03487	COG0477	Major facilitator Superfamily
C7M27_03488	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M27_03489	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7M27_03490	COG0805	protein transport
C7M27_03491	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M27_03492	COG3540	Alkaline phosphatase
C7M27_03493	COG2304	oxidoreductase activity
C7M27_03494	COG3773	Cell wall hydrolase
C7M27_03497	COG1131	(ABC) transporter
C7M27_03498	COG2205	protein histidine kinase activity
C7M27_03499	COG0745	RESPONSE REGULATOR receiver
C7M27_03500	COG0697	spore germination
C7M27_03502	COG3173	Aminoglycoside phosphotransferase
C7M27_03503	COG2721	sulfolactate sulfo-lyase activity
C7M27_03504	COG2186	Transcriptional regulator
C7M27_03505	COG4948	Mandelate Racemase Muconate Lactonizing
C7M27_03506	COG2271	Major facilitator Superfamily
C7M27_03507	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_03508	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M27_03509	COG0784	Response regulator, receiver
C7M27_03510	COG4191	Histidine kinase
C7M27_03511	COG2066	Belongs to the glutaminase family
C7M27_03512	COG1115	amino acid carrier protein
C7M27_03514	COG2040	homocysteine
C7M27_03515	COG0833	amino acid
C7M27_03516	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M27_03518	COG2188	Transcriptional regulator
C7M27_03519	COG0363	glucosamine-6-phosphate deaminase activity
C7M27_03520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M27_03520	COG2190	(PTS) system
C7M27_03520	COG1263	PTS System
C7M27_03521	COG1301	dicarboxylic acid transport
C7M27_03524	COG0688	phosphatidylethanolamine metabolic process
C7M27_03525	COG0586	Pfam SNARE associated Golgi protein
C7M27_03526	COG1183	phosphatidylcholine synthase activity
C7M27_03527	COG0596	Alpha beta hydrolase
C7M27_03529	COG3591	Belongs to the peptidase S1B family
C7M27_03530	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7M27_03531	COG2207	Transcriptional regulator
C7M27_03531	COG1917	Cupin 2, conserved barrel domain protein
C7M27_03532	COG0697	spore germination
C7M27_03534	COG2271	Major facilitator Superfamily
C7M27_03535	COG1846	Transcriptional regulator
C7M27_03535	COG0456	acetyltransferase
C7M27_03537	COG2271	Major facilitator Superfamily
C7M27_03538	COG0584	glycerophosphoryl diester phosphodiesterase
C7M27_03539	COG0531	amino acid
C7M27_03541	COG2124	cytochrome p450
C7M27_03542	COG2602	Beta-lactamase
C7M27_03545	COG1113	amino acid transport
C7M27_03548	COG0515	serine threonine protein kinase
C7M27_03551	COG2814	Major facilitator Superfamily
C7M27_03552	COG2814	Major facilitator Superfamily
C7M27_03553	COG0640	Transcriptional regulator
C7M27_03554	COG5609	conserved protein (DUF2294)
C7M27_03557	COG0288	reversible hydration of carbon dioxide
C7M27_03558	COG3002	Belongs to the UPF0753 family
C7M27_03559	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M27_03560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M27_03561	COG2169	Transcriptional regulator
C7M27_03562	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M27_03563	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M27_03564	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M27_03565	COG4856	YbbR-like protein
C7M27_03566	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M27_03567	COG5662	AntiSigma factor
C7M27_03568	COG1595	DNA-templated transcription, initiation
C7M27_03574	COG1683	Conserved Protein
C7M27_03575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M27_03576	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M27_03577	COG1737	Transcriptional regulator
C7M27_03578	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M27_03578	COG1263	PTS System
C7M27_03579	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M27_03580	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M27_03581	COG3876	Protein conserved in bacteria
C7M27_03582	COG2207	Transcriptional regulator
C7M27_03582	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M27_03583	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M27_03584	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M27_03585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M27_03586	COG2819	hydrolase of the alpha beta superfamily
C7M27_03587	COG0385	Bile acid
C7M27_03589	COG0659	secondary active sulfate transmembrane transporter activity
C7M27_03605	COG0726	polysaccharide deacetylase
C7M27_03606	COG2194	sulfuric ester hydrolase activity
C7M27_03608	COG0489	protein tyrosine kinase activity
C7M27_03609	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M27_03611	COG2226	methyltransferase
C7M27_03612	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7M27_03613	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7M27_03614	COG0101	tRNA pseudouridine synthase activity
C7M27_03615	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M27_03616	COG1122	ATPase activity
C7M27_03617	COG1122	ATPase activity
C7M27_03618	COG0203	ribosomal protein L17
C7M27_03619	COG0202	RNA polymerase activity
C7M27_03620	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7M27_03621	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7M27_03622	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M27_03624	COG0024	Methionine aminopeptidase
C7M27_03625	COG0563	adenylate kinase activity
C7M27_03626	COG0201	protein transport
C7M27_03627	COG0200	Binds to the 23S rRNA
C7M27_03630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7M27_03631	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7M27_03632	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7M27_03634	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7M27_03636	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7M27_03637	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7M27_03639	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M27_03643	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7M27_03645	COG0088	Forms part of the polypeptide exit tunnel
C7M27_03646	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7M27_03648	COG0596	Alpha beta hydrolase
C7M27_03649	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7M27_03650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7M27_03651	COG0049	tRNA binding
C7M27_03652	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7M27_03653	COG1358	cellular component organization or biogenesis
C7M27_03654	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7M27_03655	COG0085	RNA polymerase activity
C7M27_03656	COG2813	Specifically methylates the guanine in position
C7M27_03658	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7M27_03659	COG0081	regulation of translation
C7M27_03661	COG0250	Participates in transcription elongation, termination and antitermination
C7M27_03662	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M27_03663	COG1595	DNA-templated transcription, initiation
C7M27_03664	COG3688	RNA-binding protein containing a PIN domain
C7M27_03665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M27_03666	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M27_03667	COG0215	cysteine-tRNA ligase activity
C7M27_03668	COG1045	serine acetyltransferase
C7M27_03669	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7M27_03670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7M27_03671	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7M27_03672	COG4956	integral membrane protein (PIN domain superfamily)
C7M27_03673	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C7M27_03674	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7M27_03675	COG0542	response to heat
C7M27_03676	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C7M27_03677	COG3880	PFAM UvrB UvrC protein
C7M27_03678	COG4463	regulation of RNA biosynthetic process
C7M27_03694	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M27_03695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M27_03696	COG1396	sequence-specific DNA binding
C7M27_03697	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M27_03698	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7M27_03699	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7M27_03700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M27_03701	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M27_03702	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M27_03703	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M27_03704	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M27_03705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7M27_03706	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C7M27_03707	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M27_03709	COG0037	tRNA processing
C7M27_03710	COG0515	serine threonine protein kinase
C7M27_03711	COG2304	oxidoreductase activity
C7M27_03712	COG2208	phosphoserine phosphatase activity
C7M27_03715	COG1098	S1 RNA binding domain
C7M27_03716	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7M27_03719	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M27_03720	COG3956	TIGRFAM MazG family protein
C7M27_03721	COG2244	polysaccharide biosynthetic process
C7M27_03722	COG2002	toxin-antitoxin pair type II binding
C7M27_03723	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M27_03725	COG0193	aminoacyl-tRNA hydrolase activity
C7M27_03726	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7M27_03727	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M27_03728	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7M27_03729	COG2088	sporulation resulting in formation of a cellular spore
C7M27_03730	COG0251	oxidation-reduction process
C7M27_03731	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M27_03732	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7M27_03734	COG4466	Protein conserved in bacteria
C7M27_03736	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M27_03737	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M27_03738	COG3584	3D domain protein
C7M27_03738	COG3583	domain protein
C7M27_03739	COG0084	hydrolase, TatD family'
C7M27_03740	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M27_03740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M27_03741	COG2002	toxin-antitoxin pair type II binding
C7M27_03742	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7M27_03743	COG2827	Endonuclease containing a URI domain
C7M27_03744	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M27_03745	COG4467	Involved in initiation control of chromosome replication
C7M27_03746	COG1774	PSP1 C-terminal conserved region
C7M27_03747	COG0470	DNA polymerase III
C7M27_03748	COG1728	Protein conserved in bacteria
C7M27_03749	COG3870	Protein conserved in bacteria
C7M27_03750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M27_03751	COG1982	Orn Lys Arg decarboxylase major
C7M27_03752	COG3853	Toxic anion resistance protein (TelA)
C7M27_03753	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C7M27_03762	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7M27_03763	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M27_03764	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M27_03765	COG0590	tRNA wobble adenosine to inosine editing
C7M27_03766	COG1335	isochorismatase
C7M27_03767	COG1388	LysM domain
C7M27_03767	COG3858	chitin binding
C7M27_03768	COG1428	Deoxynucleoside kinase
C7M27_03769	COG1428	Deoxynucleoside kinase
C7M27_03771	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M27_03772	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C7M27_03773	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C7M27_03774	COG1686	Belongs to the peptidase S11 family
C7M27_03775	COG0517	IMP dehydrogenase activity
C7M27_03775	COG0516	GMP reductase activity
C7M27_03782	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M27_03783	COG0187	DNA topoisomerase II activity
C7M27_03785	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7M27_03786	COG2501	S4 domain
C7M27_03787	COG0592	DNA-directed DNA polymerase activity
C7M27_03788	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7M27_03789	COG0594	ribonuclease P activity
C7M27_03790	COG0706	membrane insertase activity
C7M27_03791	COG1847	R3H domain protein
C7M27_03792	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7M27_03793	COG0445	tRNA wobble uridine modification
C7M27_03794	COG0357	Ribosomal RNA small subunit methyltransferase G
C7M27_03795	COG1475	DNA binding
C7M27_03797	COG1192	Involved in chromosome partitioning
C7M27_03798	COG1475	DNA binding
C7M27_03800	COG3949	Membrane
C7M27_03801	COG4481	Protein conserved in bacteria
C7M27_03802	COG0243	molybdopterin cofactor binding
C7M27_03803	COG0012	GTP binding
C7M27_03804	COG0360	Binds together with S18 to 16S ribosomal RNA
C7M27_03805	COG0629	single-stranded DNA binding
C7M27_03806	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7M27_03807	COG0708	Exodeoxyribonuclease III
C7M27_03808	COG1609	Transcriptional regulator
C7M27_03809	COG0346	lactoylglutathione lyase activity
C7M27_03810	COG0110	maltose O-acetyltransferase activity
C7M27_03811	COG0477	Major facilitator Superfamily
C7M27_03811	COG2814	Major facilitator Superfamily
C7M27_03812	COG1266	CAAX protease self-immunity
C7M27_03813	COG1331	Highly conserved protein containing a thioredoxin domain
C7M27_03814	COG2814	Major facilitator Superfamily
C7M27_03815	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M27_03816	COG2315	Protein conserved in bacteria
C7M27_03817	COG0456	acetyltransferase
C7M27_03818	COG2364	Membrane
C7M27_03819	COG2153	protein acetylation
C7M27_03820	COG1846	Transcriptional regulator
C7M27_03821	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M27_03822	COG4319	ketosteroid isomerase
C7M27_03824	COG4978	Transcriptional regulator
C7M27_03824	COG0789	Transcriptional regulator
C7M27_03825	COG2271	Major facilitator Superfamily
C7M27_03828	COG1227	inorganic diphosphatase activity
C7M27_03829	COG1733	regulation of RNA biosynthetic process
C7M27_03830	COG5577	PFAM Coat F domain
C7M27_03832	COG4241	membrane
C7M27_03833	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7M27_03834	COG0359	binds to the 23S rRNA
C7M27_03835	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M27_03836	COG2807	transmembrane transport
C7M27_03837	COG3093	addiction module antidote protein HigA
C7M27_03840	COG0305	Participates in initiation and elongation during chromosome replication
C7M27_03841	COG0346	lactoylglutathione lyase activity
C7M27_03847	COG0745	RESPONSE REGULATOR receiver
C7M27_03848	COG5002	protein histidine kinase activity
C7M27_03849	COG4863	YycH protein
C7M27_03850	COG4853	Protein conserved in bacteria
C7M27_03851	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M27_03852	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M27_03853	COG3829	transcription factor binding
C7M27_03854	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M27_03855	COG0833	amino acid
C7M27_03856	COG0010	Belongs to the arginase family
C7M27_03858	COG0457	Tetratricopeptide repeat
C7M27_03859	COG0456	acetyltransferase
C7M27_03860	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C7M27_03864	COG1063	alcohol dehydrogenase
C7M27_03867	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7M27_03877	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C7M27_03879	COG2188	Transcriptional regulator
C7M27_03880	COG2190	(PTS) system
C7M27_03881	COG2723	6-phospho-beta-galactosidase activity
C7M27_03882	COG3634	alkyl hydroperoxide reductase activity
C7M27_03883	COG0450	alkyl hydroperoxide reductase
C7M27_03884	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M27_03885	COG2610	gluconate transmembrane transporter activity
C7M27_03886	COG1070	Carbohydrate kinase
C7M27_03887	COG1802	Transcriptional regulator
C7M27_03888	COG1929	Belongs to the glycerate kinase type-1 family
C7M27_03889	COG5039	Polysaccharide pyruvyl transferase
C7M27_03890	COG1346	cytolysis
C7M27_03891	COG1380	Effector of murein hydrolase LrgA
C7M27_03892	COG1846	Transcriptional regulator
C7M27_03893	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_03894	COG1309	transcriptional regulator
C7M27_03895	COG1917	Cupin 2, conserved barrel domain protein
C7M27_03896	COG2311	Membrane
C7M27_03897	COG1714	RDD family
C7M27_03899	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7M27_03900	COG1714	RDD family
C7M27_03901	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_03902	COG1309	transcriptional regulator
C7M27_03903	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_03905	COG0326	Molecular chaperone. Has ATPase activity
C7M27_03906	COG2814	Major facilitator Superfamily
C7M27_03909	COG0667	Aldo Keto reductase
C7M27_03910	COG1349	DNA-binding transcription factor activity
C7M27_03911	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_03913	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M27_03914	COG3962	Belongs to the TPP enzyme family
C7M27_03915	COG1082	Xylose isomerase domain protein TIM barrel
C7M27_03916	COG2814	Major facilitator Superfamily
C7M27_03917	COG0673	inositol 2-dehydrogenase activity
C7M27_03918	COG1082	Xylose isomerase domain protein TIM barrel
C7M27_03919	COG1082	Xylose isomerase domain protein TIM barrel
C7M27_03920	COG0191	fructose-bisphosphate aldolase activity
C7M27_03921	COG0745	RESPONSE REGULATOR receiver
C7M27_03922	COG2205	protein histidine kinase activity
C7M27_03923	COG1136	(ABC) transporter
C7M27_03924	COG0577	efflux transmembrane transporter activity
C7M27_03925	COG5294	Protein conserved in bacteria
C7M27_03926	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M27_03932	COG0561	phosphatase activity
C7M27_03933	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M27_03934	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M27_03935	COG0456	acetyltransferase
C7M27_03936	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M27_03937	COG0765	amino acid transport
C7M27_03938	COG1126	abc transporter atp-binding protein
C7M27_03939	COG1473	amidohydrolase
C7M27_03940	COG2079	MmgE PrpD family protein
C7M27_03941	COG3192	ethanolamine utilization protein
C7M27_03943	COG2390	Transcriptional regulator
C7M27_03944	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7M27_03945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M27_03946	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7M27_03947	COG0833	amino acid
C7M27_03948	COG0010	Belongs to the arginase family
C7M27_03949	COG1228	amidohydrolase
C7M27_03950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C7M27_03951	COG2986	histidine ammonia-lyase
C7M27_03953	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M27_03954	COG0494	nUDIX hydrolase
C7M27_03959	COG5444	nuclease activity
C7M27_03961	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M27_03961	COG1263	PTS System
C7M27_03961	COG2190	(PTS) system
C7M27_03962	COG2723	6-phospho-beta-galactosidase activity
C7M27_03963	COG0589	response to stress
C7M27_03964	COG0697	spore germination
C7M27_03965	COG3209	COG3209 Rhs family protein
C7M27_03969	COG2755	lipolytic protein G-D-S-L family
C7M27_03969	COG3401	FG-GAP repeat protein
C7M27_03970	COG0513	Belongs to the DEAD box helicase family
C7M27_03971	COG2270	Major facilitator Superfamily
C7M27_03973	COG3711	transcriptional antiterminator
C7M27_03974	COG2273	Hydrolase Family 16
C7M27_03975	COG2851	Citrate transporter
C7M27_03976	COG0753	catalase activity
C7M27_03976	COG0693	protein deglycase activity
C7M27_03979	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M27_03980	COG0500	methyltransferase
C7M27_03981	COG2610	gluconate transmembrane transporter activity
C7M27_03982	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M27_03983	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M27_03984	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_03985	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M27_03986	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M27_03987	COG4894	glucomannan catabolic process
C7M27_03989	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M27_03990	COG2197	response regulator
C7M27_03991	COG4585	Histidine kinase
C7M27_03993	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M27_03995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M27_03996	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_03997	COG2508	Transcriptional regulator
C7M27_03998	COG3842	ATPase activity
C7M27_04002	COG0726	polysaccharide deacetylase
C7M27_04004	COG0501	Belongs to the peptidase M48B family
C7M27_04005	COG3493	citrate carrier protein
C7M27_04006	COG1271	oxidase subunit
C7M27_04007	COG1294	oxidase, subunit
C7M27_04008	COG4988	ABC transporter
C7M27_04009	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M27_04010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M27_04011	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M27_04012	COG1595	DNA-templated transcription, initiation
C7M27_04016	COG1131	(ABC) transporter
C7M27_04017	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M27_04018	COG2814	Major facilitator Superfamily
C7M27_04019	COG0753	catalase activity
C7M27_04020	COG2094	Belongs to the DNA glycosylase MPG family
C7M27_04022	COG3711	transcriptional antiterminator
C7M27_04022	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M27_04023	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M27_04024	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M27_04025	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M27_04026	COG1486	melibiose metabolic process
C7M27_04027	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M27_04028	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7M27_04029	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M27_04030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M27_04031	COG1696	Membrane protein involved in D-alanine export
C7M27_04032	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M27_04033	COG1575	Belongs to the MenA family. Type 1 subfamily
C7M27_04034	COG2357	RelA SpoT domain protein
C7M27_04035	COG2814	Major facilitator Superfamily
C7M27_04038	COG2234	aminopeptidase activity
C7M27_04039	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M27_04040	COG1846	Transcriptional regulator
C7M27_04041	COG5522	Integral membrane protein (intg_mem_TP0381)
C7M27_04042	COG1442	glycosyl transferase family 8
C7M27_04043	COG3711	transcriptional antiterminator
C7M27_04044	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M27_04044	COG1263	PTS System
C7M27_04045	COG1404	Belongs to the peptidase S8 family
C7M27_04046	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M27_04048	COG0346	lactoylglutathione lyase activity
C7M27_04049	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M27_04050	COG4895	conserved protein (DUF2196)
C7M27_04051	COG2814	Major facilitator Superfamily
C7M27_04052	COG1346	cytolysis
C7M27_04053	COG1380	Effector of murein hydrolase LrgA
C7M27_04054	COG0583	DNA-binding transcription factor activity
C7M27_04055	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7M27_04056	COG0352	thiamine-phosphate diphosphorylase activity
C7M27_04057	COG0672	)-iron permease
C7M27_04058	COG2822	iron ion transport
C7M27_04059	COG2837	iron assimilation
C7M27_04060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M27_04061	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M27_04062	COG3162	membrane
C7M27_04064	COG1309	transcriptional regulator
C7M27_04065	COG2246	polysaccharide biosynthetic process
C7M27_04066	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M27_04067	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M27_04068	COG2261	transglycosylase associated protein
C7M27_04069	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M27_04070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M27_04071	COG1845	cytochrome c oxidase, subunit III
C7M27_04072	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M27_04074	COG0772	Belongs to the SEDS family
C7M27_04075	COG0778	Nitroreductase
C7M27_04076	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M27_04077	COG1404	Belongs to the peptidase S8 family
C7M27_04079	COG3711	transcriptional antiterminator
C7M27_04080	COG2116	formate transmembrane transporter activity
C7M27_04081	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M27_04081	COG1263	PTS System
C7M27_04082	COG1621	beta-fructofuranosidase activity
C7M27_04084	COG0351	phosphomethylpyrimidine kinase
C7M27_04085	COG1695	Transcriptional regulator
C7M27_04088	COG1216	Glycosyl transferase, family 2
C7M27_04089	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7M27_04090	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_04092	COG2233	PERMEase
C7M27_04093	COG2363	Small membrane protein
C7M27_04095	COG0463	Glycosyl transferase, family 2
C7M27_04096	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M27_04097	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M27_04098	COG0456	acetyltransferase
C7M27_04099	COG2089	acid synthase
C7M27_04100	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C7M27_04101	COG3980	spore coat polysaccharide biosynthesis protein
C7M27_04102	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C7M27_04103	COG1088	dTDP-glucose 4,6-dehydratase activity
C7M27_04104	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7M27_04105	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C7M27_04107	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M27_04108	COG1012	belongs to the aldehyde dehydrogenase family
C7M27_04109	COG4187	Peptidase family M20/M25/M40
C7M27_04110	COG0833	amino acid
C7M27_04111	COG2814	Major facilitator Superfamily
C7M27_04112	COG0077	Prephenate dehydratase
C7M27_04113	COG1917	Cupin 2, conserved barrel domain protein
C7M27_04114	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_04115	COG0151	Belongs to the GarS family
C7M27_04116	COG2814	Major facilitator Superfamily
C7M27_04117	COG0436	Aminotransferase
C7M27_04118	COG1028	Short-chain dehydrogenase reductase Sdr
C7M27_04120	COG0280	phosphate acetyltransferase
C7M27_04121	COG0583	DNA-binding transcription factor activity
C7M27_04122	COG0095	Lipoate-protein ligase
C7M27_04123	COG0697	spore germination
C7M27_04125	COG4844	belongs to the
C7M27_04126	COG1078	dGTPase activity
C7M27_04127	COG3465	dGTPase activity
C7M27_04128	COG1959	2 iron, 2 sulfur cluster binding
C7M27_04129	COG0477	Major facilitator Superfamily
C7M27_04131	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M27_04132	COG1846	Transcriptional regulator
C7M27_04133	COG1942	4-Oxalocrotonate Tautomerase
C7M27_04134	COG1994	Peptidase M50
C7M27_04137	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M27_04138	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7M27_04139	COG0010	Belongs to the arginase family
C7M27_04141	COG1131	(ABC) transporter
C7M27_04147	COG0457	Tetratricopeptide repeat
C7M27_04148	COG3391	amine dehydrogenase activity
C7M27_04149	COG3391	amine dehydrogenase activity
C7M27_04151	COG0612	Peptidase, M16
C7M27_04152	COG0612	Peptidase, M16
C7M27_04153	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M27_04154	COG1131	(ABC) transporter
C7M27_04156	COG0535	radical SAM domain protein
C7M27_04158	COG4506	Protein conserved in bacteria
C7M27_04159	COG0018	arginyl-trna synthetase
C7M27_04160	COG2223	nitrite transmembrane transporter activity
C7M27_04161	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M27_04163	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M27_04164	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M27_04165	COG1140	nitrate reductase beta subunit
C7M27_04166	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7M27_04167	COG2181	nitrate reductase activity
C7M27_04168	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M27_04169	COG1132	(ABC) transporter
C7M27_04170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M27_04172	COG4294	response to UV
C7M27_04173	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M27_04174	COG2181	nitrate reductase activity
C7M27_04174	COG0247	lactate metabolic process
C7M27_04175	COG1960	acyl-CoA dehydrogenase activity
C7M27_04176	COG3343	RNA polymerase activity
C7M27_04177	COG0504	CTP synthase activity
C7M27_04178	COG4821	SIS domain
C7M27_04179	COG2204	response regulator
C7M27_04180	COG0191	fructose-bisphosphate aldolase activity
C7M27_04181	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7M27_04182	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M27_04183	COG1494	fructose-1,6-bisphosphatase
C7M27_04184	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M27_04186	COG1435	thymidine kinase activity
C7M27_04187	COG0281	malic enzyme
C7M27_04188	COG0679	Auxin Efflux Carrier
C7M27_04189	COG0789	Transcriptional regulator
C7M27_04190	COG0346	lactoylglutathione lyase activity
C7M27_04191	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M27_04192	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M27_04196	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7M27_04197	COG0009	L-threonylcarbamoyladenylate synthase
C7M27_04198	COG1971	Probably functions as a manganese efflux pump
C7M27_04199	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M27_04200	COG0698	ribose 5-phosphate isomerase
C7M27_04201	COG4475	Protein of unknown function (DUF436)
C7M27_04202	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7M27_04203	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7M27_04205	COG0356	it plays a direct role in the translocation of protons across the membrane
C7M27_04207	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7M27_04208	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M27_04209	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7M27_04210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7M27_04211	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7M27_04212	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7M27_04214	COG4836	Membrane
C7M27_04216	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M27_04217	COG2385	sporulation resulting in formation of a cellular spore
C7M27_04218	COG2304	oxidoreductase activity
C7M27_04219	COG2304	oxidoreductase activity
C7M27_04221	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7M27_04222	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7M27_04223	COG0457	Tetratricopeptide repeat
C7M27_04224	COG1994	Peptidase M50
C7M27_04225	COG3237	CsbD-like
C7M27_04227	COG0831	urea catabolic process
C7M27_04228	COG0832	Belongs to the urease beta subunit family
C7M27_04229	COG0804	urea catabolic process
C7M27_04230	COG1959	2 iron, 2 sulfur cluster binding
C7M27_04231	COG2910	NAD(P)H-binding
C7M27_04233	COG0789	Transcriptional regulator
C7M27_04234	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M27_04236	COG2089	acid synthase
C7M27_04238	COG1247	-acetyltransferase
C7M27_04239	COG0739	heme binding
C7M27_04241	COG0671	phosphoesterase, PA-phosphatase related
C7M27_04242	COG0347	Belongs to the P(II) protein family
C7M27_04243	COG0004	ammonium transporteR
C7M27_04245	COG1335	isochorismatase
C7M27_04246	COG0477	Major facilitator Superfamily
C7M27_04247	COG1953	Uracil, thiamine, allantoin
C7M27_04248	COG3420	alginic acid biosynthetic process
C7M27_04249	COG2814	Major facilitator Superfamily
C7M27_04250	COG1846	Transcriptional regulator
C7M27_04251	COG1609	Transcriptional regulator
C7M27_04252	COG1077	Cell shape determining protein MreB Mrl
C7M27_04253	COG4786	Flagellar basal body rod
C7M27_04254	COG4786	Flagellar basal body rod
C7M27_04255	COG0457	Tetratricopeptide repeat
C7M27_04256	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M27_04257	COG1970	mechanosensitive ion channel activity
C7M27_04258	COG2972	Histidine kinase
C7M27_04258	COG0745	RESPONSE REGULATOR receiver
C7M27_04259	COG3279	Response regulator of the LytR AlgR family
C7M27_04261	COG3764	Sortase (surface protein transpeptidase)
C7M27_04264	COG0629	single-stranded DNA binding
C7M27_04265	COG1349	DNA-binding transcription factor activity
C7M27_04266	COG0561	phosphatase activity
C7M27_04267	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M27_04268	COG4715	Zinc finger, swim domain protein
C7M27_04270	COG3944	biosynthesis protein
C7M27_04271	COG0489	protein tyrosine kinase activity
C7M27_04272	COG4464	protein tyrosine phosphatase activity
C7M27_04273	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M27_04274	COG3878	Protein conserved in bacteria
C7M27_04277	COG5444	nuclease activity
C7M27_04279	COG1515	deoxyribonuclease V activity
C7M27_04280	COG2059	Chromate
C7M27_04281	COG2059	Chromate
C7M27_04282	COG1522	sequence-specific DNA binding
C7M27_04283	COG0405	Gamma-glutamyltransferase
C7M27_04285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M27_04287	COG5337	Spore coat protein CotH
C7M27_04289	COG1192	Involved in chromosome partitioning
C7M27_04290	COG0457	Tetratricopeptide repeat
C7M27_04295	COG0791	NLP P60 protein
C7M27_04295	COG0741	lytic transglycosylase activity
C7M27_04296	COG5644	endopeptidase inhibitor activity
C7M27_04298	COG0433	COG0433 Predicted ATPase
C7M27_04305	COG0673	inositol 2-dehydrogenase activity
C7M27_04306	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M27_04307	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7M27_04308	COG1733	regulation of RNA biosynthetic process
C7M27_04310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M27_04312	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7M27_04317	COG1063	alcohol dehydrogenase