locus-tag	class	description
C7M28_00002	COG4195	phage-related replication protein
C7M28_00003	COG1764	response to oxidative stress
C7M28_00004	COG2076	Multidrug Resistance protein
C7M28_00005	COG2076	Multidrug Resistance protein
C7M28_00008	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7M28_00009	COG1923	regulation of RNA biosynthetic process
C7M28_00012	COG1780	Probably involved in ribonucleotide reductase function
C7M28_00013	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M28_00014	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M28_00015	COG4112	unkown
C7M28_00016	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M28_00017	COG0464	growth
C7M28_00018	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M28_00019	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7M28_00020	COG0789	Transcriptional regulator
C7M28_00021	COG0174	glutamine synthetase
C7M28_00022	COG4974	Belongs to the 'phage' integrase family
C7M28_00026	COG3646	Phage regulatory protein
C7M28_00026	COG3645	SOS response
C7M28_00060	COG5280	Phage tail tape measure protein TP901
C7M28_00060	COG3953	SLT domain
C7M28_00062	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M28_00063	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M28_00068	COG4824	toxin secretion phage lysis holin
C7M28_00069	COG1388	LysM domain
C7M28_00069	COG3409	Peptidoglycan-binding domain 1 protein
C7M28_00069	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M28_00071	COG5444	nuclease activity
C7M28_00072	COG0457	Tetratricopeptide repeat
C7M28_00079	COG4282	regulation of fungal-type cell wall biogenesis
C7M28_00082	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M28_00085	COG3655	Transcriptional regulator
C7M28_00089	COG0135	phosphoribosylanthranilate isomerase activity
C7M28_00090	COG2211	Major facilitator Superfamily
C7M28_00091	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M28_00092	COG1940	carbohydrate kinase activity
C7M28_00093	COG2115	Belongs to the xylose isomerase family
C7M28_00094	COG1070	Carbohydrate kinase
C7M28_00095	COG1525	nuclease
C7M28_00096	COG2814	Major facilitator Superfamily
C7M28_00097	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M28_00099	COG0756	dUTP diphosphatase activity
C7M28_00108	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M28_00110	COG3832	glyoxalase III activity
C7M28_00113	COG0697	spore germination
C7M28_00114	COG0697	spore germination
C7M28_00120	COG4195	phage-related replication protein
C7M28_00122	COG0346	lactoylglutathione lyase activity
C7M28_00123	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7M28_00124	COG1388	LysM domain
C7M28_00125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M28_00126	COG4224	UPF0291 protein
C7M28_00127	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M28_00129	COG3763	UPF0154 protein
C7M28_00131	COG0785	Cytochrome C biogenesis protein
C7M28_00132	COG2201	protein-glutamate methylesterase activity
C7M28_00133	COG4846	Membrane protein involved in cytochrome C biogenesis
C7M28_00135	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M28_00138	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7M28_00139	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M28_00143	COG0824	Thioesterase
C7M28_00145	COG4841	protein insertion into membrane
C7M28_00146	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7M28_00147	COG1832	CoA-binding protein
C7M28_00148	COG0187	DNA topoisomerase II activity
C7M28_00149	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M28_00152	COG1115	amino acid carrier protein
C7M28_00153	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7M28_00155	COG5520	Belongs to the glycosyl hydrolase 30 family
C7M28_00156	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M28_00157	COG2246	polysaccharide biosynthetic process
C7M28_00158	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M28_00159	COG0586	Pfam SNARE associated Golgi protein
C7M28_00160	COG2404	hydrolase activity, acting on ester bonds
C7M28_00161	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M28_00162	COG1024	Enoyl-CoA hydratase
C7M28_00163	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M28_00164	COG0511	ligase activity, forming carbon-carbon bonds
C7M28_00165	COG0439	Biotin carboxylase
C7M28_00166	COG0318	PFAM AMP-dependent synthetase and ligase
C7M28_00167	COG1960	acyl-CoA dehydrogenase activity
C7M28_00168	COG1649	PFAM Uncharacterised BCR, COG1649
C7M28_00170	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M28_00170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_00171	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_00172	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_00173	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_00174	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_00175	COG2027	D-alanyl-D-alanine carboxypeptidase
C7M28_00176	COG2017	converts alpha-aldose to the beta-anomer
C7M28_00177	COG0534	Mate efflux family protein
C7M28_00180	COG0582	viral genome integration into host DNA
C7M28_00181	COG0166	Belongs to the GPI family
C7M28_00182	COG0405	Gamma-glutamyltransferase
C7M28_00183	COG0583	DNA-binding transcription factor activity
C7M28_00184	COG0604	alcohol dehydrogenase
C7M28_00185	COG0493	'glutamate synthase
C7M28_00186	COG0067	glutamate synthase
C7M28_00186	COG0069	glutamate synthase activity
C7M28_00186	COG0070	glutamate synthase
C7M28_00187	COG0583	DNA-binding transcription factor activity
C7M28_00188	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M28_00189	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M28_00191	COG0300	oxidoreductase activity
C7M28_00192	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M28_00194	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M28_00197	COG1131	(ABC) transporter
C7M28_00199	COG2814	Major facilitator Superfamily
C7M28_00200	COG1070	Carbohydrate kinase
C7M28_00201	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M28_00202	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M28_00203	COG0243	molybdopterin cofactor binding
C7M28_00205	COG2814	Major facilitator Superfamily
C7M28_00206	COG0673	inositol 2-dehydrogenase activity
C7M28_00207	COG1082	Xylose isomerase domain protein TIM barrel
C7M28_00208	COG1609	Transcriptional regulator
C7M28_00212	COG0840	transmembrane signaling receptor activity
C7M28_00212	COG5278	phosphoserine phosphatase activity
C7M28_00213	COG2368	4-hydroxyphenylacetate
C7M28_00214	COG4305	rare lipoprotein A
C7M28_00215	COG3619	membrane
C7M28_00216	COG3866	Pectate lyase
C7M28_00217	COG2135	peptidase activity
C7M28_00219	COG2140	Oxalate decarboxylase
C7M28_00223	COG2720	vancomycin resistance protein
C7M28_00225	COG3655	Transcriptional regulator
C7M28_00226	COG3739	integral membrane protein
C7M28_00227	COG0583	DNA-binding transcription factor activity
C7M28_00228	COG0697	spore germination
C7M28_00230	COG0693	protein deglycase activity
C7M28_00231	COG2367	Beta-lactamase
C7M28_00234	COG0574	Belongs to the PEP-utilizing enzyme family
C7M28_00234	COG3848	Pyruvate phosphate dikinase
C7M28_00235	COG0726	polysaccharide deacetylase
C7M28_00239	COG2205	protein histidine kinase activity
C7M28_00241	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C7M28_00242	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C7M28_00245	COG5444	nuclease activity
C7M28_00246	COG4282	regulation of fungal-type cell wall biogenesis
C7M28_00247	COG1231	oxidoreductase activity
C7M28_00248	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M28_00249	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M28_00250	COG2207	Transcriptional regulator
C7M28_00250	COG0662	Cupin 2, conserved barrel domain protein
C7M28_00251	COG0456	acetyltransferase
C7M28_00252	COG1309	transcriptional regulator
C7M28_00253	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M28_00254	COG3708	Transcriptional regulator
C7M28_00255	COG2378	regulation of single-species biofilm formation
C7M28_00257	COG0640	Transcriptional regulator
C7M28_00258	COG0741	lytic transglycosylase activity
C7M28_00259	COG2322	membrane
C7M28_00262	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M28_00263	COG3239	Fatty acid desaturase
C7M28_00264	COG4585	Histidine kinase
C7M28_00265	COG2197	response regulator
C7M28_00266	COG3584	3D domain protein
C7M28_00266	COG1388	LysM domain
C7M28_00267	COG0514	ATP-dependent DNA helicase (RecQ)
C7M28_00268	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M28_00269	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M28_00272	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M28_00277	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_00278	COG1657	PFAM Prenyltransferase squalene oxidase
C7M28_00279	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M28_00280	COG0733	neurotransmitter:sodium symporter activity
C7M28_00281	COG0385	Bile acid
C7M28_00282	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M28_00283	COG0567	Dehydrogenase, E1 component
C7M28_00284	COG4548	von Willebrand factor, type A
C7M28_00285	COG0714	Associated with various cellular activities
C7M28_00286	COG2032	superoxide dismutase activity
C7M28_00287	COG0791	NLP P60 protein
C7M28_00287	COG1388	LysM domain
C7M28_00288	COG1819	glycosyl
C7M28_00289	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M28_00291	COG0534	Mate efflux family protein
C7M28_00292	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M28_00293	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M28_00294	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M28_00296	COG2962	Rard protein
C7M28_00299	COG2610	gluconate transmembrane transporter activity
C7M28_00300	COG1942	4-Oxalocrotonate Tautomerase
C7M28_00301	COG1733	regulation of RNA biosynthetic process
C7M28_00302	COG0778	Nitroreductase
C7M28_00303	COG0400	carboxylic ester hydrolase activity
C7M28_00304	COG0346	lactoylglutathione lyase activity
C7M28_00306	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M28_00307	COG0793	Belongs to the peptidase S41A family
C7M28_00307	COG3409	Peptidoglycan-binding domain 1 protein
C7M28_00308	COG2226	methyltransferase
C7M28_00310	COG1876	peptidase activity
C7M28_00311	COG0813	purine-nucleoside phosphorylase activity
C7M28_00314	COG0671	phosphoesterase, PA-phosphatase related
C7M28_00318	COG4479	Belongs to the UPF0346 family
C7M28_00320	COG1509	lysine 2,3-aminomutase activity
C7M28_00321	COG0456	acetyltransferase
C7M28_00322	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M28_00323	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M28_00324	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M28_00325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M28_00327	COG0456	acetyltransferase
C7M28_00328	COG0463	Glycosyl transferase, family 2
C7M28_00331	COG4641	Protein conserved in bacteria
C7M28_00332	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
C7M28_00333	COG1086	Polysaccharide biosynthesis protein
C7M28_00334	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M28_00335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M28_00336	COG1846	Transcriptional regulator
C7M28_00337	COG0534	Mate efflux family protein
C7M28_00339	COG4698	Protein conserved in bacteria
C7M28_00340	COG2755	lipolytic protein G-D-S-L family
C7M28_00341	COG1999	signal sequence binding
C7M28_00343	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M28_00344	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M28_00345	COG1272	protein, Hemolysin III
C7M28_00346	COG0204	Acyl-transferase
C7M28_00347	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M28_00348	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7M28_00349	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M28_00351	COG2136	Putative SAM-dependent methyltransferase
C7M28_00351	COG2521	methyltransferase
C7M28_00353	COG0129	dihydroxy-acid dehydratase activity
C7M28_00354	COG1413	lyase activity
C7M28_00355	COG1418	mRNA catabolic process
C7M28_00356	COG0386	Belongs to the glutathione peroxidase family
C7M28_00357	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7M28_00358	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M28_00359	COG1278	Cold shock
C7M28_00363	COG0328	RNA-DNA hybrid ribonuclease activity
C7M28_00364	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7M28_00365	COG0328	RNA-DNA hybrid ribonuclease activity
C7M28_00367	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M28_00370	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M28_00372	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7M28_00373	COG3424	synthase
C7M28_00374	COG2233	PERMEase
C7M28_00375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M28_00376	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7M28_00378	COG0800	Aldolase
C7M28_00379	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M28_00380	COG1609	Transcriptional regulator
C7M28_00381	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C7M28_00382	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_00383	COG1199	ATP-dependent helicase activity
C7M28_00385	COG0116	Belongs to the methyltransferase superfamily
C7M28_00387	COG4474	Belongs to the UPF0398 family
C7M28_00388	COG3359	exonuclease
C7M28_00389	COG1111	helicase
C7M28_00389	COG1205	dead DEAH box helicase
C7M28_00390	COG2190	(PTS) system
C7M28_00391	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M28_00398	COG3331	DNA recombination
C7M28_00399	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M28_00399	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M28_00401	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M28_00402	COG3935	DnaD domain protein
C7M28_00403	COG0017	Asparaginyl-tRNA synthetase
C7M28_00404	COG0436	Aminotransferase
C7M28_00405	COG5353	protein conserved in bacteria
C7M28_00407	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M28_00407	COG1199	ATP-dependent helicase activity
C7M28_00408	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7M28_00409	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7M28_00410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7M28_00411	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C7M28_00411	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C7M28_00412	COG0617	tRNA 3'-terminal CCA addition
C7M28_00413	COG0438	transferase activity, transferring glycosyl groups
C7M28_00414	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M28_00415	COG1803	Methylglyoxal synthase
C7M28_00416	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7M28_00417	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M28_00418	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M28_00420	COG4347	Protein of unknown function (DUF1405)
C7M28_00421	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M28_00421	COG2010	Cytochrome c
C7M28_00422	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M28_00423	COG0723	plastoquinol--plastocyanin reductase activity
C7M28_00425	COG5582	Belongs to the UPF0302 family
C7M28_00426	COG0457	Tetratricopeptide repeat
C7M28_00427	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7M28_00428	COG0287	Prephenate dehydrogenase
C7M28_00429	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7M28_00430	COG0159	tryptophan synthase activity
C7M28_00431	COG0133	tryptophan synthase activity
C7M28_00432	COG0135	phosphoribosylanthranilate isomerase activity
C7M28_00434	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M28_00435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M28_00436	COG4401	Chorismate mutase type I
C7M28_00437	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7M28_00438	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7M28_00439	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7M28_00440	COG0105	UTP biosynthetic process
C7M28_00441	COG0142	geranyltranstransferase activity
C7M28_00442	COG2226	methyltransferase
C7M28_00443	COG0142	geranyltranstransferase activity
C7M28_00445	COG0302	gtp cyclohydrolase
C7M28_00446	COG0776	regulation of translation
C7M28_00447	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M28_00450	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7M28_00451	COG1160	GTP binding
C7M28_00456	COG1304	FMN binding
C7M28_00457	COG0539	negative regulation of cytoplasmic translation
C7M28_00458	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7M28_00460	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7M28_00461	COG2959	enzyme of heme biosynthesis
C7M28_00462	COG3773	Cell wall hydrolase
C7M28_00462	COG3409	Peptidoglycan-binding domain 1 protein
C7M28_00463	COG2339	peptidase activity
C7M28_00464	COG0492	ferredoxin-NADP+ reductase activity
C7M28_00465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M28_00466	COG4862	establishment of competence for transformation
C7M28_00467	COG1408	metallophosphoesterase
C7M28_00469	COG1388	LysM domain
C7M28_00470	COG1266	CAAX protease self-immunity
C7M28_00471	COG0514	ATP-dependent DNA helicase (RecQ)
C7M28_00472	COG4955	Helix-turn-helix domain
C7M28_00473	COG1141	Ferredoxin
C7M28_00474	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M28_00475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M28_00476	COG0710	3-dehydroquinate dehydratase activity
C7M28_00478	COG1595	DNA-templated transcription, initiation
C7M28_00479	COG5002	protein histidine kinase activity
C7M28_00480	COG0745	RESPONSE REGULATOR receiver
C7M28_00481	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M28_00482	COG1333	cytochrome c biogenesis protein
C7M28_00483	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M28_00484	COG1187	pseudouridine synthase activity
C7M28_00485	COG0700	Nucleoside recognition
C7M28_00486	COG2715	membrane protein required for spore maturation
C7M28_00487	COG1686	Belongs to the peptidase S11 family
C7M28_00489	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7M28_00490	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7M28_00491	COG1547	Domain of unknown function (DUF309)
C7M28_00492	COG0456	acetyltransferase
C7M28_00493	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7M28_00494	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M28_00494	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M28_00495	COG0307	riboflavin synthase, alpha
C7M28_00496	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M28_00496	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M28_00498	COG0681	Belongs to the peptidase S26 family
C7M28_00499	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
C7M28_00504	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M28_00509	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M28_00510	COG4086	secreted protein
C7M28_00511	COG0019	diaminopimelate decarboxylase activity
C7M28_00512	COG0697	spore germination
C7M28_00515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M28_00519	COG1191	sigma factor activity
C7M28_00520	COG2172	sigma factor antagonist activity
C7M28_00521	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M28_00522	COG1686	Belongs to the peptidase S11 family
C7M28_00523	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7M28_00524	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M28_00525	COG4974	Belongs to the 'phage' integrase family
C7M28_00527	COG0735	belongs to the Fur family
C7M28_00528	COG1300	Membrane
C7M28_00530	COG0281	malic enzyme
C7M28_00531	COG1757	Na H antiporter
C7M28_00532	COG1027	Aspartate ammonia-lyase
C7M28_00533	COG0252	asparaginase activity
C7M28_00534	COG1396	sequence-specific DNA binding
C7M28_00535	COG1379	DNA repair
C7M28_00536	COG0494	nUDIX hydrolase
C7M28_00538	COG0667	Aldo Keto reductase
C7M28_00540	COG1073	alpha beta
C7M28_00542	COG4918	Iron-sulphur cluster biosynthesis
C7M28_00543	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M28_00543	COG0456	acetyltransferase
C7M28_00544	COG2329	Antibiotic biosynthesis monooxygenase
C7M28_00545	COG0456	acetyltransferase
C7M28_00547	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M28_00549	COG2211	Major facilitator Superfamily
C7M28_00551	COG0346	lactoylglutathione lyase activity
C7M28_00552	COG1072	(Pantothenic acid kinase))
C7M28_00553	COG3048	D-serine ammonia-lyase activity
C7M28_00554	COG0300	oxidoreductase activity
C7M28_00555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M28_00556	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M28_00557	COG4187	Peptidase family M20/M25/M40
C7M28_00558	COG1902	pentaerythritol trinitrate reductase activity
C7M28_00559	COG0596	Alpha beta hydrolase
C7M28_00561	COG1234	tRNA 3'-trailer cleavage
C7M28_00562	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M28_00563	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M28_00564	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M28_00566	COG0706	membrane insertase activity
C7M28_00567	COG3361	conserved protein (COG2071)
C7M28_00568	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M28_00569	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M28_00570	COG0346	lactoylglutathione lyase activity
C7M28_00572	COG1376	ErfK ybiS ycfS ynhG family protein
C7M28_00573	COG4129	membrane
C7M28_00574	COG1126	abc transporter atp-binding protein
C7M28_00575	COG0765	amino acid transport
C7M28_00576	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M28_00578	COG1597	lipid kinase activity
C7M28_00579	COG2814	Major facilitator Superfamily
C7M28_00580	COG4978	Transcriptional regulator
C7M28_00580	COG0789	Transcriptional regulator
C7M28_00581	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M28_00582	COG0022	dehydrogenase e1 component
C7M28_00583	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M28_00584	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M28_00585	COG3426	butyrate kinase activity
C7M28_00586	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M28_00587	COG0280	phosphate acetyltransferase
C7M28_00588	COG3290	protein histidine kinase activity
C7M28_00588	COG3829	transcription factor binding
C7M28_00590	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7M28_00591	COG2079	MmgE PrpD family protein
C7M28_00592	COG0372	Belongs to the citrate synthase family
C7M28_00593	COG1960	acyl-CoA dehydrogenase activity
C7M28_00594	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M28_00595	COG0183	Belongs to the thiolase family
C7M28_00596	COG0584	glycerophosphoryl diester phosphodiesterase
C7M28_00597	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M28_00599	COG1902	pentaerythritol trinitrate reductase activity
C7M28_00601	COG0745	RESPONSE REGULATOR receiver
C7M28_00602	COG0750	zinc metalloprotease
C7M28_00603	COG0497	DNA recombination
C7M28_00604	COG1438	arginine binding
C7M28_00605	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M28_00606	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7M28_00607	COG0142	geranyltranstransferase activity
C7M28_00608	COG1722	exodeoxyribonuclease VII activity
C7M28_00609	COG1570	exodeoxyribonuclease VII activity
C7M28_00610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7M28_00611	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M28_00612	COG1302	Protein conserved in bacteria
C7M28_00613	COG0439	Biotin carboxylase
C7M28_00614	COG0511	ligase activity, forming carbon-carbon bonds
C7M28_00622	COG3854	ATPases associated with a variety of cellular activities
C7M28_00624	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7M28_00625	COG0006	proline dipeptidase activity
C7M28_00626	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7M28_00628	COG3872	metal-dependent enzyme
C7M28_00630	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M28_00631	COG1321	iron dependent repressor
C7M28_00632	COG0095	Lipoate-protein ligase
C7M28_00633	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M28_00634	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M28_00635	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M28_00636	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7M28_00637	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M28_00640	COG1396	sequence-specific DNA binding
C7M28_00642	COG0681	Belongs to the peptidase S26 family
C7M28_00647	COG4940	Competence protein ComGF
C7M28_00649	COG4970	Tfp pilus assembly protein FimT
C7M28_00650	COG4537	Required for transformation and DNA binding
C7M28_00651	COG1459	type II secretion system
C7M28_00652	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M28_00653	COG0517	IMP dehydrogenase activity
C7M28_00654	COG0598	Magnesium transport protein CorA
C7M28_00655	COG1253	flavin adenine dinucleotide binding
C7M28_00656	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M28_00658	COG1393	Belongs to the ArsC family
C7M28_00660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M28_00662	COG0011	TIGRFAM Protein of
C7M28_00664	COG2866	Carboxypeptidase
C7M28_00665	COG1368	sulfuric ester hydrolase activity
C7M28_00666	COG1940	carbohydrate kinase activity
C7M28_00667	COG4483	Protein conserved in bacteria
C7M28_00668	COG0705	Rhomboid family
C7M28_00668	COG0457	Tetratricopeptide repeat
C7M28_00670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M28_00672	COG0438	transferase activity, transferring glycosyl groups
C7M28_00675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M28_00676	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M28_00677	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M28_00678	COG0581	inorganic phosphate transmembrane transporter activity
C7M28_00679	COG0573	inorganic phosphate transmembrane transporter activity
C7M28_00680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M28_00682	COG0477	Major facilitator Superfamily
C7M28_00683	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M28_00684	COG2839	Protein conserved in bacteria
C7M28_00685	COG5521	maltodextrose utilization protein MalA
C7M28_00686	COG1388	LysM domain
C7M28_00687	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7M28_00688	COG4709	membrane
C7M28_00689	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C7M28_00690	COG0735	belongs to the Fur family
C7M28_00691	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M28_00693	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7M28_00694	COG0513	Belongs to the DEAD box helicase family
C7M28_00696	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7M28_00697	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M28_00698	COG2384	SAM-dependent methyltransferase
C7M28_00699	COG2010	Cytochrome c
C7M28_00700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M28_00701	COG0358	DNA primase activity
C7M28_00702	COG1671	Belongs to the UPF0178 family
C7M28_00703	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7M28_00704	COG0517	IMP dehydrogenase activity
C7M28_00705	COG0751	glycine-tRNA ligase activity
C7M28_00706	COG0752	glycyl-tRNA synthetase alpha subunit
C7M28_00707	COG1381	Involved in DNA repair and RecF pathway recombination
C7M28_00709	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M28_00710	COG0295	cytidine deaminase activity
C7M28_00711	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M28_00712	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7M28_00713	COG1480	7TM receptor with intracellular HD hydrolase
C7M28_00715	COG1702	phosphate starvation-inducible protein PhoH
C7M28_00716	COG0561	phosphatase activity
C7M28_00719	COG4864	UPF0365 protein
C7M28_00720	COG1030	water channel activity
C7M28_00721	COG1610	YqeY-like protein
C7M28_00723	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M28_00724	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M28_00725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M28_00726	COG2264	protein methyltransferase activity
C7M28_00727	COG0484	heat shock protein binding
C7M28_00728	COG0443	Heat shock 70 kDa protein
C7M28_00729	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7M28_00730	COG1420	regulation of RNA biosynthetic process
C7M28_00731	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M28_00732	COG0481	GTPase activity
C7M28_00734	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M28_00735	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7M28_00736	COG0268	Binds directly to 16S ribosomal RNA
C7M28_00737	COG1466	dna polymerase III delta subunit
C7M28_00739	COG2333	competence protein COMEC
C7M28_00739	COG0658	competence protein
C7M28_00740	COG2131	deaminase
C7M28_00741	COG1596	polysaccharide export
C7M28_00741	COG1555	photosystem II stabilization
C7M28_00742	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M28_00743	COG2226	methyltransferase
C7M28_00744	COG0799	negative regulation of ribosome biogenesis
C7M28_00745	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M28_00746	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7M28_00747	COG1534	Rna-binding protein
C7M28_00748	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M28_00749	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M28_00750	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7M28_00752	COG2755	lipolytic protein G-D-S-L family
C7M28_00753	COG3409	Peptidoglycan-binding domain 1 protein
C7M28_00753	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M28_00754	COG0398	Pfam SNARE associated Golgi protein
C7M28_00755	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7M28_00757	COG3209	COG3209 Rhs family protein
C7M28_00761	COG4124	Belongs to the glycosyl hydrolase 26 family
C7M28_00762	COG0730	response to heat
C7M28_00763	COG0425	Belongs to the sulfur carrier protein TusA family
C7M28_00764	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M28_00764	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M28_00765	COG0425	Belongs to the sulfur carrier protein TusA family
C7M28_00765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M28_00766	COG2210	Belongs to the sulfur carrier protein TusA family
C7M28_00767	COG1937	Protein conserved in bacteria
C7M28_00768	COG0662	Cupin 2, conserved barrel domain protein
C7M28_00769	COG0789	Transcriptional regulator
C7M28_00769	COG4978	Transcriptional regulator
C7M28_00770	COG2814	Major facilitator Superfamily
C7M28_00771	COG0456	acetyltransferase
C7M28_00772	COG1253	flavin adenine dinucleotide binding
C7M28_00774	COG0697	spore germination
C7M28_00775	COG0583	DNA-binding transcription factor activity
C7M28_00776	COG2072	flavoprotein involved in K transport
C7M28_00777	COG1230	cation diffusion facilitator family transporter
C7M28_00778	COG1942	4-Oxalocrotonate Tautomerase
C7M28_00779	COG0583	DNA-binding transcription factor activity
C7M28_00780	COG1114	Component of the transport system for branched-chain amino acids
C7M28_00781	COG1687	branched-chain amino acid
C7M28_00782	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C7M28_00783	COG1522	sequence-specific DNA binding
C7M28_00784	COG2732	(Barnase) inhibitor
C7M28_00785	COG1335	isochorismatase
C7M28_00787	COG2318	DinB family
C7M28_00789	COG2070	2-Nitropropane dioxygenase
C7M28_00790	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M28_00793	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7M28_00794	COG1595	DNA-templated transcription, initiation
C7M28_00795	COG0667	Aldo Keto reductase
C7M28_00796	COG2851	Citrate transporter
C7M28_00797	COG0583	DNA-binding transcription factor activity
C7M28_00798	COG2828	Protein conserved in bacteria
C7M28_00800	COG3409	Peptidoglycan-binding domain 1 protein
C7M28_00801	COG5566	PFAM Mor transcription activator
C7M28_00802	COG0596	Alpha beta hydrolase
C7M28_00803	COG4991	sh3 domain protein
C7M28_00804	COG4991	sh3 domain protein
C7M28_00805	COG0346	lactoylglutathione lyase activity
C7M28_00807	COG5577	PFAM Coat F domain
C7M28_00808	COG1063	alcohol dehydrogenase
C7M28_00810	COG5577	PFAM Coat F domain
C7M28_00811	COG0789	Transcriptional regulator
C7M28_00813	COG1064	alcohol dehydrogenase
C7M28_00814	COG0693	protein deglycase activity
C7M28_00815	COG1621	beta-fructofuranosidase activity
C7M28_00816	COG3716	PTS system mannose fructose sorbose family IID component
C7M28_00817	COG3715	PTS system
C7M28_00818	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M28_00819	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M28_00820	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M28_00820	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7M28_00821	COG1113	amino acid transport
C7M28_00822	COG1280	lysine exporter protein (LysE YggA)
C7M28_00823	COG1378	Sugar-specific transcriptional regulator TrmB
C7M28_00824	COG1595	DNA-templated transcription, initiation
C7M28_00826	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M28_00826	COG2755	lipolytic protein G-D-S-L family
C7M28_00831	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M28_00832	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7M28_00833	COG2986	histidine ammonia-lyase
C7M28_00834	COG2084	Dehydrogenase
C7M28_00838	COG1131	(ABC) transporter
C7M28_00839	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M28_00841	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M28_00841	COG2124	cytochrome p450
C7M28_00842	COG1309	transcriptional regulator
C7M28_00843	COG2226	methyltransferase
C7M28_00846	COG2116	formate transmembrane transporter activity
C7M28_00847	COG5609	conserved protein (DUF2294)
C7M28_00848	COG3383	formate dehydrogenase (NAD+) activity
C7M28_00849	COG2427	Protein of unknown function (DUF1641)
C7M28_00851	COG0626	cystathionine gamma-synthase activity
C7M28_00852	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M28_00853	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7M28_00854	COG2226	methyltransferase
C7M28_00857	COG0768	penicillin binding
C7M28_00858	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M28_00859	COG0572	uridine kinase
C7M28_00862	COG4122	O-methyltransferase activity
C7M28_00863	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M28_00864	COG3906	Belongs to the UPF0473 family
C7M28_00865	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7M28_00866	COG4472	Bacterial protein of unknown function (DUF965)
C7M28_00867	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7M28_00868	COG0628	permease
C7M28_00869	COG1126	abc transporter atp-binding protein
C7M28_00870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M28_00871	COG0765	amino acid transport
C7M28_00872	COG0765	amino acid transport
C7M28_00875	COG3881	PFAM PRC-barrel domain
C7M28_00876	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M28_00877	COG0457	Tetratricopeptide repeat
C7M28_00878	COG0482	sulfurtransferase activity
C7M28_00879	COG1104	cysteine desulfurase activity
C7M28_00880	COG1959	2 iron, 2 sulfur cluster binding
C7M28_00881	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M28_00882	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7M28_00883	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7M28_00884	COG0124	histidyl-tRNA synthetase
C7M28_00886	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M28_00886	COG3103	Sh3 type 3 domain protein
C7M28_00886	COG4991	sh3 domain protein
C7M28_00887	COG1490	D-aminoacyl-tRNA deacylase activity
C7M28_00888	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M28_00889	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M28_00890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M28_00890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M28_00891	COG5416	Lipopolysaccharide assembly protein A domain
C7M28_00892	COG0490	domain, Protein
C7M28_00893	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M28_00893	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M28_00895	COG2244	polysaccharide biosynthetic process
C7M28_00896	COG2323	membrane
C7M28_00898	COG1862	Preprotein translocase
C7M28_00899	COG0343	queuine tRNA-ribosyltransferase activity
C7M28_00900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7M28_00902	COG2255	four-way junction helicase activity
C7M28_00903	COG0632	four-way junction helicase activity
C7M28_00905	COG2814	Major facilitator Superfamily
C7M28_00906	COG0673	inositol 2-dehydrogenase activity
C7M28_00907	COG2112	serine threonine protein kinase
C7M28_00910	COG1115	amino acid carrier protein
C7M28_00911	COG0217	transcriptional regulatory protein
C7M28_00913	COG1388	LysM domain
C7M28_00914	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7M28_00915	COG0157	Belongs to the NadC ModD family
C7M28_00916	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7M28_00917	COG1104	cysteine desulfurase activity
C7M28_00918	COG1827	regulation of RNA biosynthetic process
C7M28_00919	COG0077	Prephenate dehydratase
C7M28_00920	COG4492	Belongs to the UPF0735 family
C7M28_00921	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7M28_00922	COG3290	protein histidine kinase activity
C7M28_00923	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M28_00924	COG2868	ribosomal protein
C7M28_00925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7M28_00926	COG1994	Peptidase M50
C7M28_00927	COG0739	heme binding
C7M28_00928	COG2894	cell division
C7M28_00929	COG0850	regulation of cytokinetic process
C7M28_00930	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7M28_00932	COG1077	Cell shape determining protein MreB Mrl
C7M28_00933	COG2003	Belongs to the UPF0758 family
C7M28_00934	COG0424	maF-like protein
C7M28_00936	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M28_00937	COG0285	dihydrofolate synthase activity
C7M28_00938	COG0525	valine-tRNA ligase activity
C7M28_00940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M28_00941	COG1388	LysM domain
C7M28_00942	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M28_00943	COG0113	porphobilinogen synthase activity
C7M28_00944	COG1587	Uroporphyrinogen-III synthase
C7M28_00945	COG0181	hydroxymethylbilane synthase activity
C7M28_00946	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M28_00947	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7M28_00949	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7M28_00950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7M28_00951	COG0470	DNA polymerase III
C7M28_00951	COG1067	ATP-dependent peptidase activity
C7M28_00952	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7M28_00953	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7M28_00954	COG0457	Tetratricopeptide repeat
C7M28_00954	COG1477	protein flavinylation
C7M28_00955	COG0066	3-isopropylmalate dehydratase activity
C7M28_00956	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7M28_00957	COG0473	3-isopropylmalate dehydrogenase activity
C7M28_00958	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M28_00959	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7M28_00960	COG0440	acetolactate synthase activity
C7M28_00961	COG0028	Belongs to the TPP enzyme family
C7M28_00963	COG0454	-acetyltransferase
C7M28_00964	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
C7M28_00966	COG0622	Phosphoesterase
C7M28_00967	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M28_00968	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7M28_00969	COG5401	PFAM Sporulation and spore germination
C7M28_00970	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M28_00971	COG1846	Transcriptional regulator
C7M28_00972	COG2197	response regulator
C7M28_00973	COG0824	Thioesterase
C7M28_00974	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7M28_00975	COG1053	succinate dehydrogenase
C7M28_00976	COG2009	succinate dehydrogenase
C7M28_00977	COG1719	4-vinyl reductase, 4VR
C7M28_00978	COG0527	aspartate kinase activity
C7M28_00979	COG0322	excinuclease ABC activity
C7M28_00980	COG3118	belongs to the thioredoxin family
C7M28_00981	COG3534	alpha-L-arabinofuranosidase
C7M28_00983	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M28_00984	COG2086	electron transfer activity
C7M28_00985	COG1024	Enoyl-CoA hydratase
C7M28_00986	COG1309	transcriptional regulator
C7M28_00987	COG0318	PFAM AMP-dependent synthetase and ligase
C7M28_00988	COG3766	membrane
C7M28_00989	COG1193	negative regulation of DNA recombination
C7M28_00990	COG1796	DNA polymerase
C7M28_00990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M28_00991	COG1286	toxin biosynthetic process
C7M28_00992	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C7M28_00993	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M28_00994	COG0072	phenylalanine-tRNA ligase activity
C7M28_00994	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M28_00995	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M28_00996	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M28_00998	COG3835	regulator
C7M28_00999	COG0277	FAD linked oxidase domain protein
C7M28_01000	COG0247	lactate metabolic process
C7M28_01001	COG0346	lactoylglutathione lyase activity
C7M28_01002	COG1966	Carbon starvation protein
C7M28_01003	COG3534	alpha-L-arabinofuranosidase
C7M28_01004	COG0395	ABC-type sugar transport system, permease component
C7M28_01005	COG1175	transmembrane transport
C7M28_01006	COG1653	transport
C7M28_01007	COG0371	Dehydrogenase
C7M28_01008	COG0647	UMP catabolic process
C7M28_01009	COG0235	Class ii aldolase
C7M28_01010	COG1069	ribulokinase activity
C7M28_01011	COG2160	L-arabinose isomerase activity
C7M28_01012	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M28_01013	COG1363	Peptidase, m42
C7M28_01015	COG3326	Membrane
C7M28_01016	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7M28_01017	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7M28_01018	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M28_01020	COG1346	cytolysis
C7M28_01021	COG1380	Effector of murein hydrolase LrgA
C7M28_01022	COG3279	Response regulator of the LytR AlgR family
C7M28_01023	COG3275	phosphorelay sensor kinase activity
C7M28_01024	COG1011	Hydrolase
C7M28_01025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M28_01027	COG0398	Pfam SNARE associated Golgi protein
C7M28_01028	COG1484	DNA-dependent DNA replication
C7M28_01029	COG3611	Membrane attachment protein
C7M28_01030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7M28_01031	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C7M28_01032	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M28_01033	COG1733	regulation of RNA biosynthetic process
C7M28_01034	COG2814	Major facilitator Superfamily
C7M28_01035	COG0656	L-ascorbic acid biosynthetic process
C7M28_01036	COG0237	dephospho-CoA kinase activity
C7M28_01037	COG1971	Probably functions as a manganese efflux pump
C7M28_01038	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M28_01039	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M28_01039	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M28_01040	COG5002	protein histidine kinase activity
C7M28_01041	COG0745	RESPONSE REGULATOR receiver
C7M28_01042	COG0039	L-malate dehydrogenase activity
C7M28_01043	COG0538	isocitrate dehydrogenase activity
C7M28_01044	COG0372	Belongs to the citrate synthase family
C7M28_01045	COG2707	UPF0756 membrane protein
C7M28_01046	COG0628	permease
C7M28_01047	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7M28_01048	COG0469	pyruvate kinase activity
C7M28_01049	COG0205	6-phosphofructokinase activity
C7M28_01050	COG0825	malonyl-CoA metabolic process
C7M28_01051	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7M28_01052	COG0281	malic enzyme
C7M28_01053	COG0587	DNA-directed DNA polymerase activity
C7M28_01057	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M28_01059	COG4109	DRTGG domain
C7M28_01060	COG0730	response to heat
C7M28_01061	COG1473	amidohydrolase
C7M28_01062	COG0196	riboflavin kinase activity
C7M28_01063	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M28_01064	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7M28_01065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M28_01066	COG1126	abc transporter atp-binding protein
C7M28_01067	COG0765	amino acid transport
C7M28_01068	COG0765	amino acid transport
C7M28_01069	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M28_01070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M28_01071	COG0454	-acetyltransferase
C7M28_01072	COG0583	DNA-binding transcription factor activity
C7M28_01073	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7M28_01074	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_01076	COG0165	Argininosuccinate lyase
C7M28_01077	COG0137	argininosuccinate synthase activity
C7M28_01078	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7M28_01079	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M28_01080	COG0827	DNA restriction-modification system
C7M28_01081	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7M28_01082	COG3874	Sporulation protein YtfJ
C7M28_01084	COG1714	RDD family
C7M28_01085	COG0616	signal peptide processing
C7M28_01086	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M28_01087	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C7M28_01088	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M28_01090	COG0301	tRNA thio-modification
C7M28_01091	COG1104	cysteine desulfurase activity
C7M28_01092	COG1114	Component of the transport system for branched-chain amino acids
C7M28_01093	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7M28_01094	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M28_01095	COG1309	transcriptional regulator
C7M28_01096	COG1956	GAF domain-containing protein
C7M28_01097	COG2203	Gaf domain
C7M28_01097	COG2199	diguanylate cyclase activity
C7M28_01098	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7M28_01100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M28_01101	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M28_01102	COG0454	-acetyltransferase
C7M28_01103	COG0517	IMP dehydrogenase activity
C7M28_01104	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7M28_01105	COG1360	Flagellar Motor Protein
C7M28_01106	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M28_01107	COG1609	Transcriptional regulator
C7M28_01108	COG1605	Chorismate mutase
C7M28_01108	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M28_01109	COG3118	belongs to the thioredoxin family
C7M28_01110	COG4980	gas vesicle protein
C7M28_01111	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M28_01112	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7M28_01113	COG1674	ftsk spoiiie
C7M28_01114	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M28_01115	COG4848	Belongs to the UPF0354 family
C7M28_01116	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M28_01118	COG1363	Peptidase, m42
C7M28_01119	COG5584	Small secreted protein
C7M28_01120	COG0281	malic enzyme
C7M28_01121	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M28_01122	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7M28_01124	COG0510	thiamine kinase activity
C7M28_01125	COG1523	belongs to the glycosyl hydrolase 13 family
C7M28_01126	COG1597	lipid kinase activity
C7M28_01128	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M28_01129	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M28_01130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M28_01131	COG2252	PERMEase
C7M28_01132	COG4473	ABC transporter
C7M28_01133	COG1131	(ABC) transporter
C7M28_01134	COG1349	DNA-binding transcription factor activity
C7M28_01135	COG1187	pseudouridine synthase activity
C7M28_01136	COG2244	polysaccharide biosynthetic process
C7M28_01137	COG2081	HI0933 family
C7M28_01138	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M28_01140	COG5578	integral membrane protein
C7M28_01141	COG0673	inositol 2-dehydrogenase activity
C7M28_01142	COG1653	transport
C7M28_01143	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M28_01144	COG4209	transmembrane transport
C7M28_01145	COG2207	Transcriptional regulator
C7M28_01146	COG1653	transport
C7M28_01147	COG0395	ABC-type sugar transport system, permease component
C7M28_01148	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M28_01149	COG2124	cytochrome p450
C7M28_01150	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7M28_01152	COG0156	8-amino-7-oxononanoate synthase activity
C7M28_01153	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M28_01155	COG1073	alpha beta
C7M28_01156	COG1609	Transcriptional regulator
C7M28_01157	COG1653	transport
C7M28_01158	COG1175	transmembrane transport
C7M28_01159	COG0395	ABC-type sugar transport system, permease component
C7M28_01160	COG1486	melibiose metabolic process
C7M28_01161	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M28_01162	COG0495	leucyl-tRNA aminoacylation
C7M28_01164	COG2202	Pas domain
C7M28_01164	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M28_01165	COG2814	Major facilitator Superfamily
C7M28_01166	COG2433	Pfam Transposase IS66
C7M28_01167	COG0577	efflux transmembrane transporter activity
C7M28_01168	COG1136	(ABC) transporter
C7M28_01169	COG2205	protein histidine kinase activity
C7M28_01170	COG0745	RESPONSE REGULATOR receiver
C7M28_01171	COG0577	efflux transmembrane transporter activity
C7M28_01172	COG1136	(ABC) transporter
C7M28_01175	COG1131	(ABC) transporter
C7M28_01176	COG1725	Transcriptional regulator
C7M28_01179	COG1242	4 iron, 4 sulfur cluster binding
C7M28_01180	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M28_01182	COG2267	carboxylic ester hydrolase activity
C7M28_01183	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M28_01184	COG1113	amino acid transport
C7M28_01185	COG0367	asparagine synthase
C7M28_01186	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7M28_01187	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7M28_01189	COG1506	peptidase
C7M28_01190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M28_01191	COG1116	anion transmembrane transporter activity
C7M28_01192	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M28_01193	COG0494	nUDIX hydrolase
C7M28_01194	COG4824	toxin secretion phage lysis holin
C7M28_01195	COG0783	Belongs to the Dps family
C7M28_01198	COG1854	S-ribosylhomocysteine lyase activity
C7M28_01199	COG0288	reversible hydration of carbon dioxide
C7M28_01200	COG0254	rRNA binding
C7M28_01201	COG1271	oxidase subunit
C7M28_01202	COG1294	oxidase, subunit
C7M28_01204	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M28_01205	COG1321	iron dependent repressor
C7M28_01205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M28_01206	COG1121	(ABC) transporter
C7M28_01207	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M28_01208	COG4948	Mandelate Racemase Muconate Lactonizing
C7M28_01209	COG0318	PFAM AMP-dependent synthetase and ligase
C7M28_01210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7M28_01211	COG0596	Alpha beta hydrolase
C7M28_01212	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7M28_01213	COG1169	isochorismate synthase
C7M28_01214	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M28_01215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M28_01216	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M28_01217	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M28_01218	COG0438	transferase activity, transferring glycosyl groups
C7M28_01220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M28_01221	COG0438	transferase activity, transferring glycosyl groups
C7M28_01222	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M28_01223	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M28_01224	COG0058	SHG alpha-glucan phosphorylase activity
C7M28_01225	COG0297	glycogen (starch) synthase activity
C7M28_01226	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M28_01227	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M28_01228	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7M28_01253	COG3859	Proton-coupled thiamine transporter YuaJ
C7M28_01254	COG1247	-acetyltransferase
C7M28_01255	COG2268	Band 7 protein
C7M28_01256	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7M28_01257	COG2318	DinB family
C7M28_01259	COG1454	alcohol dehydrogenase
C7M28_01260	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_01261	COG1510	regulation of RNA biosynthetic process
C7M28_01263	COG0569	domain protein
C7M28_01264	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M28_01265	COG4682	membrane
C7M28_01266	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M28_01267	COG0477	Major facilitator Superfamily
C7M28_01268	COG5553	Cysteine dioxygenase type I
C7M28_01270	COG1968	undecaprenyl-diphosphatase activity
C7M28_01271	COG0628	permease
C7M28_01272	COG0673	inositol 2-dehydrogenase activity
C7M28_01273	COG4806	L-rhamnose isomerase
C7M28_01274	COG3254	rhamnose metabolic process
C7M28_01275	COG1070	Carbohydrate kinase
C7M28_01276	COG1349	DNA-binding transcription factor activity
C7M28_01277	COG3347	Dehydrogenase
C7M28_01277	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_01279	COG0840	transmembrane signaling receptor activity
C7M28_01280	COG0840	transmembrane signaling receptor activity
C7M28_01281	COG0840	transmembrane signaling receptor activity
C7M28_01282	COG0840	transmembrane signaling receptor activity
C7M28_01285	COG0432	Pfam Uncharacterised protein family UPF0047
C7M28_01286	COG0366	Alpha amylase catalytic
C7M28_01287	COG1253	flavin adenine dinucleotide binding
C7M28_01288	COG2738	Putative neutral zinc metallopeptidase
C7M28_01291	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M28_01294	COG0166	Belongs to the GPI family
C7M28_01295	COG1979	alcohol dehydrogenase
C7M28_01296	COG1979	alcohol dehydrogenase
C7M28_01297	COG2155	Conserved Protein
C7M28_01298	COG1098	S1 RNA binding domain
C7M28_01299	COG0436	Aminotransferase
C7M28_01300	COG1522	sequence-specific DNA binding
C7M28_01301	COG2267	carboxylic ester hydrolase activity
C7M28_01303	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M28_01304	COG2205	protein histidine kinase activity
C7M28_01306	COG5018	Exonuclease
C7M28_01308	COG2814	Major facilitator Superfamily
C7M28_01309	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M28_01310	COG3011	Protein conserved in bacteria
C7M28_01312	COG3290	protein histidine kinase activity
C7M28_01313	COG4565	transcriptional regulatory protein
C7M28_01318	COG3493	citrate carrier protein
C7M28_01320	COG2111	Na H antiporter
C7M28_01320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M28_01321	COG2111	Na H antiporter
C7M28_01322	COG1006	Multisubunit Na H antiporter MnhC subunit
C7M28_01323	COG0651	ATP synthesis coupled electron transport
C7M28_01324	COG1863	multisubunit Na H antiporter MnhE subunit
C7M28_01325	COG2212	antiporter activity
C7M28_01326	COG1320	monovalent cation:proton antiporter activity
C7M28_01327	COG2050	protein possibly involved in aromatic compounds catabolism
C7M28_01328	COG2197	response regulator
C7M28_01329	COG4585	Histidine kinase
C7M28_01331	COG0142	geranyltranstransferase activity
C7M28_01335	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7M28_01336	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M28_01337	COG1335	isochorismatase
C7M28_01338	COG5506	Protein of unknown function (DUF1694)
C7M28_01341	COG0628	permease
C7M28_01344	COG1418	mRNA catabolic process
C7M28_01345	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_01347	COG1511	domain protein
C7M28_01348	COG0433	COG0433 Predicted ATPase
C7M28_01348	COG1674	ftsk spoiiie
C7M28_01349	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M28_01350	COG5417	Belongs to the EsaB family
C7M28_01351	COG4842	Belongs to the WXG100 family
C7M28_01352	COG2508	Transcriptional regulator
C7M28_01352	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M28_01353	COG0686	Belongs to the AlaDH PNT family
C7M28_01354	COG5634	Uncharacterized conserved protein (DUF2278)
C7M28_01355	COG3251	PFAM MbtH domain protein
C7M28_01356	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_01357	COG1535	isochorismatase
C7M28_01357	COG3433	isochorismatase activity
C7M28_01358	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7M28_01359	COG1169	isochorismate synthase
C7M28_01360	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_01361	COG2819	hydrolase of the alpha beta superfamily
C7M28_01362	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M28_01363	COG1268	BioY protein
C7M28_01364	COG2056	Na+-H+ antiporter family
C7M28_01365	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7M28_01366	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7M28_01367	COG3584	3D domain protein
C7M28_01369	COG1252	NADH dehydrogenase
C7M28_01370	COG0492	ferredoxin-NADP+ reductase activity
C7M28_01372	COG0516	GMP reductase activity
C7M28_01373	COG2808	Putative FMN-binding domain
C7M28_01374	COG0456	acetyltransferase
C7M28_01375	COG0316	Belongs to the HesB IscA family
C7M28_01376	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7M28_01377	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M28_01378	COG4844	belongs to the
C7M28_01379	COG1252	NADH dehydrogenase
C7M28_01380	COG4837	Protein of unknown function (DUF1462)
C7M28_01381	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7M28_01382	COG0823	Involved in the tonB-independent uptake of proteins
C7M28_01382	COG1506	peptidase
C7M28_01382	COG4946	Tricorn protease homolog
C7M28_01383	COG0083	homoserine kinase activity
C7M28_01384	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7M28_01385	COG0460	homoserine dehydrogenase
C7M28_01386	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M28_01387	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M28_01388	COG0647	UMP catabolic process
C7M28_01389	COG2445	Protein of unknown function DUF86
C7M28_01390	COG4470	Protein conserved in bacteria
C7M28_01392	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7M28_01393	COG0739	heme binding
C7M28_01395	COG3377	Domain of unknown function (DUF1805)
C7M28_01396	COG0737	Belongs to the 5'-nucleotidase family
C7M28_01397	COG0730	response to heat
C7M28_01398	COG1801	Protein of unknown function DUF72
C7M28_01400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M28_01401	COG2508	Transcriptional regulator
C7M28_01402	COG2233	PERMEase
C7M28_01403	COG2233	PERMEase
C7M28_01404	COG3195	allantoin biosynthetic process
C7M28_01404	COG3648	Uricase
C7M28_01405	COG2351	hydroxyisourate hydrolase activity
C7M28_01406	COG2080	2 iron, 2 sulfur cluster binding
C7M28_01407	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7M28_01408	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C7M28_01409	COG2068	MobA-Related Protein
C7M28_01410	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7M28_01412	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M28_01413	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M28_01414	COG2356	endonuclease I
C7M28_01415	COG3842	ATPase activity
C7M28_01416	COG2188	Transcriptional regulator
C7M28_01417	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M28_01418	COG0395	ABC-type sugar transport system, permease component
C7M28_01419	COG1175	transmembrane transport
C7M28_01420	COG1653	transport
C7M28_01421	COG2222	sugar isomerase
C7M28_01422	COG0322	excinuclease ABC activity
C7M28_01423	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M28_01426	COG0346	lactoylglutathione lyase activity
C7M28_01427	COG0719	Fe-S assembly protein
C7M28_01428	COG0822	iron-sulfur transferase activity
C7M28_01429	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M28_01430	COG0719	Fe-S assembly protein
C7M28_01431	COG0396	ATPase activity
C7M28_01432	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M28_01433	COG1464	Belongs to the NlpA lipoprotein family
C7M28_01434	COG2011	ABC-type metal ion transport system permease component
C7M28_01435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M28_01437	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M28_01438	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M28_01440	COG0509	glycine decarboxylation via glycine cleavage system
C7M28_01441	COG1393	Belongs to the ArsC family
C7M28_01442	COG1960	acyl-CoA dehydrogenase activity
C7M28_01443	COG0183	Belongs to the thiolase family
C7M28_01444	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M28_01444	COG1024	Enoyl-CoA hydratase
C7M28_01446	COG0506	proline dehydrogenase activity
C7M28_01448	COG5577	PFAM Coat F domain
C7M28_01449	COG1846	Transcriptional regulator
C7M28_01450	COG0477	Major facilitator Superfamily
C7M28_01451	COG1942	4-Oxalocrotonate Tautomerase
C7M28_01452	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_01453	COG0583	DNA-binding transcription factor activity
C7M28_01455	COG1120	ATPase activity
C7M28_01458	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_01459	COG0783	Belongs to the Dps family
C7M28_01460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M28_01461	COG0745	RESPONSE REGULATOR receiver
C7M28_01462	COG2205	protein histidine kinase activity
C7M28_01462	COG2770	Histidine kinase
C7M28_01463	COG1309	transcriptional regulator
C7M28_01464	COG0114	fumarate hydratase activity
C7M28_01466	COG0697	spore germination
C7M28_01467	COG0814	amino acid
C7M28_01469	COG2197	response regulator
C7M28_01470	COG4585	Histidine kinase
C7M28_01471	COG4758	membrane
C7M28_01472	COG3595	metallopeptidase activity
C7M28_01473	COG1842	Phage shock protein A
C7M28_01474	COG4758	membrane
C7M28_01475	COG2814	Major facilitator Superfamily
C7M28_01476	COG2096	Adenosyltransferase
C7M28_01477	COG1120	ATPase activity
C7M28_01478	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M28_01479	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M28_01480	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_01481	COG3386	PFAM SMP-30 Gluconolaconase
C7M28_01482	COG2205	protein histidine kinase activity
C7M28_01483	COG0745	RESPONSE REGULATOR receiver
C7M28_01485	COG1191	sigma factor activity
C7M28_01487	COG2140	Oxalate decarboxylase
C7M28_01489	COG0577	efflux transmembrane transporter activity
C7M28_01490	COG1136	(ABC) transporter
C7M28_01491	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M28_01492	COG1120	ATPase activity
C7M28_01493	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M28_01494	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M28_01495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M28_01497	COG0531	amino acid
C7M28_01499	COG1988	membrane-bound metal-dependent
C7M28_01500	COG1368	sulfuric ester hydrolase activity
C7M28_01501	COG1910	domain protein
C7M28_01502	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7M28_01503	COG4149	molybdate abc transporter
C7M28_01504	COG0656	L-ascorbic acid biosynthetic process
C7M28_01506	COG0025	NhaP-type Na H and K H
C7M28_01507	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M28_01508	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M28_01509	COG3973	AAA domain
C7M28_01511	COG2860	membrane
C7M28_01512	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M28_01513	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7M28_01514	COG2217	Heavy metal translocating P-type atpase
C7M28_01515	COG2217	Heavy metal translocating P-type atpase
C7M28_01516	COG2608	mercury ion transmembrane transporter activity
C7M28_01517	COG1937	Protein conserved in bacteria
C7M28_01518	COG0673	inositol 2-dehydrogenase activity
C7M28_01519	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M28_01520	COG1289	transmembrane transporter activity
C7M28_01522	COG2076	Multidrug Resistance protein
C7M28_01523	COG1309	transcriptional regulator
C7M28_01524	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_01526	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7M28_01527	COG0557	exoribonuclease II activity
C7M28_01528	COG1647	Serine aminopeptidase, S33
C7M28_01529	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M28_01530	COG0596	Alpha beta hydrolase
C7M28_01531	COG1476	TRANSCRIPTIONal
C7M28_01532	COG1396	sequence-specific DNA binding
C7M28_01533	COG1396	sequence-specific DNA binding
C7M28_01534	COG1733	regulation of RNA biosynthetic process
C7M28_01535	COG0840	transmembrane signaling receptor activity
C7M28_01536	COG1174	glycine betaine transport
C7M28_01537	COG1732	Glycine betaine
C7M28_01538	COG1174	glycine betaine transport
C7M28_01539	COG1125	glycine betaine transport
C7M28_01539	COG0517	IMP dehydrogenase activity
C7M28_01540	COG1510	regulation of RNA biosynthetic process
C7M28_01541	COG1174	glycine betaine transport
C7M28_01542	COG1732	Glycine betaine
C7M28_01543	COG1174	glycine betaine transport
C7M28_01544	COG0517	IMP dehydrogenase activity
C7M28_01544	COG1125	glycine betaine transport
C7M28_01545	COG1510	regulation of RNA biosynthetic process
C7M28_01546	COG2095	MarC family integral membrane protein
C7M28_01548	COG3064	Membrane
C7M28_01549	COG4640	response to antibiotic
C7M28_01550	COG0456	acetyltransferase
C7M28_01551	COG0148	phosphopyruvate hydratase activity
C7M28_01552	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7M28_01553	COG0149	triose-phosphate isomerase activity
C7M28_01554	COG0126	phosphoglycerate kinase activity
C7M28_01555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M28_01556	COG2390	Transcriptional regulator
C7M28_01557	COG2814	Major facilitator Superfamily
C7M28_01558	COG1609	Transcriptional regulator
C7M28_01559	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M28_01560	COG0583	DNA-binding transcription factor activity
C7M28_01561	COG0697	spore germination
C7M28_01562	COG1113	amino acid transport
C7M28_01563	COG3858	chitin binding
C7M28_01564	COG1556	Lactate utilization protein
C7M28_01565	COG1139	Iron-sulfur cluster binding protein
C7M28_01566	COG0247	lactate metabolic process
C7M28_01567	COG2197	response regulator
C7M28_01568	COG4585	Histidine kinase
C7M28_01569	COG0842	Transport permease protein
C7M28_01570	COG1131	(ABC) transporter
C7M28_01571	COG0596	Alpha beta hydrolase
C7M28_01572	COG2208	phosphoserine phosphatase activity
C7M28_01573	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C7M28_01574	COG1874	Beta-galactosidase
C7M28_01575	COG3833	ABC-type maltose transport systems, permease component
C7M28_01576	COG1175	transmembrane transport
C7M28_01577	COG2182	Extracellular solute-binding protein
C7M28_01578	COG1609	Transcriptional regulator
C7M28_01579	COG2186	Transcriptional regulator
C7M28_01580	COG1620	l-lactate permease
C7M28_01581	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M28_01583	COG5039	Polysaccharide pyruvyl transferase
C7M28_01584	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M28_01585	COG0110	maltose O-acetyltransferase activity
C7M28_01586	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M28_01587	COG2244	polysaccharide biosynthetic process
C7M28_01588	COG1216	Glycosyl transferase, family 2
C7M28_01589	COG5039	Polysaccharide pyruvyl transferase
C7M28_01590	COG1216	Glycosyl transferase, family 2
C7M28_01592	COG0438	transferase activity, transferring glycosyl groups
C7M28_01593	COG1215	transferase activity, transferring glycosyl groups
C7M28_01594	COG0438	transferase activity, transferring glycosyl groups
C7M28_01595	COG1086	Polysaccharide biosynthesis protein
C7M28_01596	COG0489	protein tyrosine kinase activity
C7M28_01597	COG3944	biosynthesis protein
C7M28_01598	COG1396	sequence-specific DNA binding
C7M28_01599	COG2272	Belongs to the type-B carboxylesterase lipase family
C7M28_01601	COG3479	Phenolic acid decarboxylase
C7M28_01603	COG1794	racemase activity, acting on amino acids and derivatives
C7M28_01604	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M28_01605	COG1621	beta-fructofuranosidase activity
C7M28_01606	COG1621	beta-fructofuranosidase activity
C7M28_01607	COG0531	amino acid
C7M28_01608	COG1309	transcriptional regulator
C7M28_01609	COG2076	Multidrug Resistance protein
C7M28_01610	COG2076	Multidrug Resistance protein
C7M28_01612	COG0277	FAD linked oxidase domain protein
C7M28_01613	COG3621	Patatin-like phospholipase
C7M28_01615	COG0740	serine-type endopeptidase activity
C7M28_01616	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M28_01617	COG0366	Alpha amylase catalytic
C7M28_01618	COG1554	hydrolase, family 65, central catalytic
C7M28_01619	COG5521	maltodextrose utilization protein MalA
C7M28_01620	COG3833	ABC-type maltose transport systems, permease component
C7M28_01621	COG1175	transmembrane transport
C7M28_01622	COG2182	Extracellular solute-binding protein
C7M28_01623	COG0366	Alpha amylase catalytic
C7M28_01624	COG1609	Transcriptional regulator
C7M28_01625	COG1611	Belongs to the LOG family
C7M28_01626	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M28_01627	COG0659	secondary active sulfate transmembrane transporter activity
C7M28_01628	COG0288	reversible hydration of carbon dioxide
C7M28_01629	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M28_01630	COG0577	efflux transmembrane transporter activity
C7M28_01631	COG1136	(ABC) transporter
C7M28_01632	COG5002	protein histidine kinase activity
C7M28_01633	COG0745	RESPONSE REGULATOR receiver
C7M28_01635	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7M28_01636	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M28_01637	COG1481	regulation of sporulation
C7M28_01638	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M28_01639	COG1660	Displays ATPase and GTPase activities
C7M28_01640	COG1051	belongs to the nudix hydrolase family
C7M28_01641	COG0492	ferredoxin-NADP+ reductase activity
C7M28_01642	COG3883	PFAM NLP P60 protein
C7M28_01642	COG0791	NLP P60 protein
C7M28_01643	COG0457	Tetratricopeptide repeat
C7M28_01644	COG1132	(ABC) transporter
C7M28_01649	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M28_01649	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M28_01650	COG0107	imidazoleglycerol-phosphate synthase activity
C7M28_01651	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7M28_01652	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7M28_01653	COG0131	Imidazoleglycerol-phosphate dehydratase
C7M28_01654	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M28_01655	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7M28_01656	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7M28_01657	COG4990	cell redox homeostasis
C7M28_01658	COG5297	Belongs to the glycosyl hydrolase family 6
C7M28_01659	COG0110	maltose O-acetyltransferase activity
C7M28_01660	COG0546	phosphoglycolate phosphatase activity
C7M28_01661	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7M28_01662	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7M28_01663	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7M28_01664	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7M28_01665	COG0363	glucosamine-6-phosphate deaminase activity
C7M28_01666	COG2188	Transcriptional regulator
C7M28_01667	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M28_01668	COG1846	Transcriptional regulator
C7M28_01669	COG2124	cytochrome p450
C7M28_01671	COG1846	Transcriptional regulator
C7M28_01672	COG2814	Major facilitator Superfamily
C7M28_01673	COG1950	PFAM Membrane protein of
C7M28_01674	COG1983	PspC domain protein
C7M28_01675	COG3595	metallopeptidase activity
C7M28_01678	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M28_01679	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M28_01680	COG0556	nucleotide-excision repair
C7M28_01681	COG4897	Protein conserved in bacteria
C7M28_01682	COG0574	Belongs to the PEP-utilizing enzyme family
C7M28_01682	COG3848	Pyruvate phosphate dikinase
C7M28_01683	COG1309	transcriptional regulator
C7M28_01684	COG2814	Major facilitator Superfamily
C7M28_01685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M28_01687	COG0793	Belongs to the peptidase S41A family
C7M28_01687	COG3409	Peptidoglycan-binding domain 1 protein
C7M28_01688	COG2177	Part of the ABC transporter FtsEX involved in
C7M28_01689	COG2884	Cell division ATP-binding protein ftsE
C7M28_01690	COG2010	Cytochrome c
C7M28_01691	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M28_01692	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C7M28_01693	COG0653	protein targeting
C7M28_01694	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7M28_01697	COG1516	flagellar protein fliS
C7M28_01698	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7M28_01699	COG1334	flagellar protein FlaG
C7M28_01700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M28_01701	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C7M28_01702	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C7M28_01704	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M28_01705	COG4786	Flagellar basal body rod
C7M28_01705	COG1256	bacterial-type flagellum assembly
C7M28_01706	COG3418	PFAM FlgN family protein
C7M28_01707	COG2747	anti-sigma28 factor FlgM
C7M28_01709	COG1040	competence protein
C7M28_01711	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M28_01712	COG1307	EDD domain protein, DegV family
C7M28_01713	COG2197	response regulator
C7M28_01714	COG4585	Histidine kinase
C7M28_01715	COG1739	Uncharacterized protein family UPF0029
C7M28_01716	COG1316	TRANSCRIPTIONal
C7M28_01717	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M28_01718	COG0438	transferase activity, transferring glycosyl groups
C7M28_01719	COG1215	transferase activity, transferring glycosyl groups
C7M28_01720	COG3206	protein involved in exopolysaccharide biosynthesis
C7M28_01721	COG3307	-O-antigen
C7M28_01722	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M28_01723	COG0438	transferase activity, transferring glycosyl groups
C7M28_01723	COG0297	glycogen (starch) synthase activity
C7M28_01724	COG2244	polysaccharide biosynthetic process
C7M28_01726	COG2247	cell wall binding repeat
C7M28_01726	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M28_01727	COG2385	sporulation resulting in formation of a cellular spore
C7M28_01727	COG2247	cell wall binding repeat
C7M28_01729	COG1316	TRANSCRIPTIONal
C7M28_01730	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M28_01731	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M28_01733	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M28_01733	COG1215	transferase activity, transferring glycosyl groups
C7M28_01734	COG0463	Glycosyl transferase, family 2
C7M28_01736	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M28_01737	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M28_01738	COG1134	teichoic acid transport
C7M28_01739	COG1682	transport, permease protein
C7M28_01740	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M28_01741	COG0438	transferase activity, transferring glycosyl groups
C7M28_01742	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M28_01743	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C7M28_01744	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M28_01746	COG4193	domain, Protein
C7M28_01747	COG1482	cell wall glycoprotein biosynthetic process
C7M28_01748	COG0697	spore germination
C7M28_01749	COG0814	amino acid
C7M28_01751	COG2814	Major facilitator Superfamily
C7M28_01752	COG1316	TRANSCRIPTIONal
C7M28_01753	COG0561	phosphatase activity
C7M28_01754	COG0791	NLP P60 protein
C7M28_01756	COG2843	Capsule synthesis protein
C7M28_01758	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M28_01759	COG1609	Transcriptional regulator
C7M28_01760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M28_01761	COG1869	D-ribose catabolic process
C7M28_01762	COG1129	ABC transporter
C7M28_01763	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7M28_01764	COG1879	ABC-type sugar transport system periplasmic component
C7M28_01765	COG3103	Sh3 type 3 domain protein
C7M28_01767	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M28_01768	COG3527	Alpha-acetolactate decarboxylase
C7M28_01769	COG0028	Belongs to the TPP enzyme family
C7M28_01770	COG0583	DNA-binding transcription factor activity
C7M28_01771	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M28_01774	COG5337	Spore coat protein CotH
C7M28_01776	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M28_01778	COG0405	Gamma-glutamyltransferase
C7M28_01779	COG1522	sequence-specific DNA binding
C7M28_01780	COG2059	Chromate
C7M28_01781	COG2059	Chromate
C7M28_01783	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M28_01784	COG0583	DNA-binding transcription factor activity
C7M28_01787	COG5444	nuclease activity
C7M28_01790	COG5444	nuclease activity
C7M28_01793	COG3878	Protein conserved in bacteria
C7M28_01794	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M28_01795	COG4464	protein tyrosine phosphatase activity
C7M28_01796	COG0489	protein tyrosine kinase activity
C7M28_01797	COG3944	biosynthesis protein
C7M28_01799	COG4715	Zinc finger, swim domain protein
C7M28_01800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M28_01801	COG0561	phosphatase activity
C7M28_01802	COG1349	DNA-binding transcription factor activity
C7M28_01803	COG0629	single-stranded DNA binding
C7M28_01806	COG3764	Sortase (surface protein transpeptidase)
C7M28_01807	COG2972	Histidine kinase
C7M28_01807	COG0745	RESPONSE REGULATOR receiver
C7M28_01808	COG1970	mechanosensitive ion channel activity
C7M28_01809	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M28_01810	COG0457	Tetratricopeptide repeat
C7M28_01811	COG4786	Flagellar basal body rod
C7M28_01812	COG4786	Flagellar basal body rod
C7M28_01813	COG1077	Cell shape determining protein MreB Mrl
C7M28_01814	COG1609	Transcriptional regulator
C7M28_01815	COG1846	Transcriptional regulator
C7M28_01816	COG2814	Major facilitator Superfamily
C7M28_01817	COG3420	alginic acid biosynthetic process
C7M28_01818	COG1953	Uracil, thiamine, allantoin
C7M28_01819	COG0477	Major facilitator Superfamily
C7M28_01820	COG1335	isochorismatase
C7M28_01822	COG0004	ammonium transporteR
C7M28_01823	COG0347	Belongs to the P(II) protein family
C7M28_01824	COG0671	phosphoesterase, PA-phosphatase related
C7M28_01826	COG0739	heme binding
C7M28_01827	COG1247	-acetyltransferase
C7M28_01830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M28_01831	COG0789	Transcriptional regulator
C7M28_01833	COG2910	NAD(P)H-binding
C7M28_01834	COG1959	2 iron, 2 sulfur cluster binding
C7M28_01835	COG0804	urea catabolic process
C7M28_01836	COG0832	Belongs to the urease beta subunit family
C7M28_01837	COG0831	urea catabolic process
C7M28_01839	COG3237	CsbD-like
C7M28_01840	COG1994	Peptidase M50
C7M28_01841	COG0457	Tetratricopeptide repeat
C7M28_01842	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7M28_01843	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7M28_01845	COG2304	oxidoreductase activity
C7M28_01846	COG2304	oxidoreductase activity
C7M28_01847	COG2385	sporulation resulting in formation of a cellular spore
C7M28_01848	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M28_01850	COG4836	Membrane
C7M28_01853	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7M28_01854	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7M28_01855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7M28_01856	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7M28_01857	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M28_01858	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7M28_01860	COG0356	it plays a direct role in the translocation of protons across the membrane
C7M28_01862	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7M28_01863	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7M28_01864	COG4475	Protein of unknown function (DUF436)
C7M28_01865	COG0698	ribose 5-phosphate isomerase
C7M28_01866	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M28_01867	COG1971	Probably functions as a manganese efflux pump
C7M28_01868	COG0009	L-threonylcarbamoyladenylate synthase
C7M28_01869	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7M28_01873	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M28_01874	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M28_01875	COG0346	lactoylglutathione lyase activity
C7M28_01876	COG0789	Transcriptional regulator
C7M28_01877	COG0679	Auxin Efflux Carrier
C7M28_01878	COG0281	malic enzyme
C7M28_01879	COG1435	thymidine kinase activity
C7M28_01881	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M28_01882	COG1494	fructose-1,6-bisphosphatase
C7M28_01883	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M28_01884	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7M28_01885	COG0191	fructose-bisphosphate aldolase activity
C7M28_01886	COG2204	response regulator
C7M28_01887	COG4821	SIS domain
C7M28_01888	COG0504	CTP synthase activity
C7M28_01889	COG3343	RNA polymerase activity
C7M28_01890	COG1960	acyl-CoA dehydrogenase activity
C7M28_01891	COG0247	lactate metabolic process
C7M28_01891	COG2181	nitrate reductase activity
C7M28_01892	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M28_01893	COG4294	response to UV
C7M28_01895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M28_01896	COG1132	(ABC) transporter
C7M28_01897	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M28_01898	COG2181	nitrate reductase activity
C7M28_01899	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7M28_01900	COG1140	nitrate reductase beta subunit
C7M28_01901	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M28_01902	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M28_01904	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M28_01905	COG2223	nitrite transmembrane transporter activity
C7M28_01906	COG0018	arginyl-trna synthetase
C7M28_01907	COG4506	Protein conserved in bacteria
C7M28_01909	COG0535	radical SAM domain protein
C7M28_01911	COG1131	(ABC) transporter
C7M28_01912	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M28_01913	COG0612	Peptidase, M16
C7M28_01914	COG0612	Peptidase, M16
C7M28_01916	COG3391	amine dehydrogenase activity
C7M28_01917	COG3391	amine dehydrogenase activity
C7M28_01918	COG0457	Tetratricopeptide repeat
C7M28_01920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M28_01921	COG0010	Belongs to the arginase family
C7M28_01922	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7M28_01923	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M28_01926	COG1994	Peptidase M50
C7M28_01927	COG1942	4-Oxalocrotonate Tautomerase
C7M28_01928	COG1846	Transcriptional regulator
C7M28_01929	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M28_01931	COG0477	Major facilitator Superfamily
C7M28_01932	COG1959	2 iron, 2 sulfur cluster binding
C7M28_01933	COG3465	dGTPase activity
C7M28_01934	COG1078	dGTPase activity
C7M28_01935	COG4844	belongs to the
C7M28_01937	COG0697	spore germination
C7M28_01938	COG0095	Lipoate-protein ligase
C7M28_01939	COG0583	DNA-binding transcription factor activity
C7M28_01940	COG0280	phosphate acetyltransferase
C7M28_01942	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_01943	COG0436	Aminotransferase
C7M28_01944	COG2814	Major facilitator Superfamily
C7M28_01945	COG0151	Belongs to the GarS family
C7M28_01946	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_01947	COG1917	Cupin 2, conserved barrel domain protein
C7M28_01948	COG0077	Prephenate dehydratase
C7M28_01949	COG2814	Major facilitator Superfamily
C7M28_01950	COG0833	amino acid
C7M28_01951	COG4187	Peptidase family M20/M25/M40
C7M28_01952	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_01953	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M28_01955	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C7M28_01956	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7M28_01957	COG1088	dTDP-glucose 4,6-dehydratase activity
C7M28_01958	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C7M28_01959	COG3980	spore coat polysaccharide biosynthesis protein
C7M28_01960	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C7M28_01961	COG2089	acid synthase
C7M28_01962	COG0456	acetyltransferase
C7M28_01963	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M28_01964	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M28_01965	COG0463	Glycosyl transferase, family 2
C7M28_01967	COG2363	Small membrane protein
C7M28_01968	COG2233	PERMEase
C7M28_01970	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_01971	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7M28_01972	COG1216	Glycosyl transferase, family 2
C7M28_01973	COG0351	phosphomethylpyrimidine kinase
C7M28_01975	COG1621	beta-fructofuranosidase activity
C7M28_01976	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M28_01976	COG1263	PTS System
C7M28_01977	COG2116	formate transmembrane transporter activity
C7M28_01978	COG3711	transcriptional antiterminator
C7M28_01980	COG1404	Belongs to the peptidase S8 family
C7M28_01981	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M28_01982	COG0778	Nitroreductase
C7M28_01983	COG0772	Belongs to the SEDS family
C7M28_01985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M28_01986	COG1845	cytochrome c oxidase, subunit III
C7M28_01987	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M28_01988	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M28_01989	COG2261	transglycosylase associated protein
C7M28_01990	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M28_01991	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M28_01992	COG2246	polysaccharide biosynthetic process
C7M28_01993	COG1309	transcriptional regulator
C7M28_01995	COG3162	membrane
C7M28_01996	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M28_01997	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M28_01998	COG2837	iron assimilation
C7M28_01999	COG2822	iron ion transport
C7M28_02000	COG0672	)-iron permease
C7M28_02001	COG0352	thiamine-phosphate diphosphorylase activity
C7M28_02002	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7M28_02003	COG0583	DNA-binding transcription factor activity
C7M28_02004	COG1380	Effector of murein hydrolase LrgA
C7M28_02005	COG1346	cytolysis
C7M28_02006	COG2814	Major facilitator Superfamily
C7M28_02007	COG4895	conserved protein (DUF2196)
C7M28_02008	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M28_02009	COG0346	lactoylglutathione lyase activity
C7M28_02012	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M28_02013	COG1404	Belongs to the peptidase S8 family
C7M28_02014	COG1263	PTS System
C7M28_02014	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M28_02015	COG3711	transcriptional antiterminator
C7M28_02016	COG1442	glycosyl transferase family 8
C7M28_02017	COG5522	Integral membrane protein (intg_mem_TP0381)
C7M28_02018	COG1846	Transcriptional regulator
C7M28_02019	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M28_02020	COG2234	aminopeptidase activity
C7M28_02023	COG2814	Major facilitator Superfamily
C7M28_02024	COG2357	RelA SpoT domain protein
C7M28_02025	COG1575	Belongs to the MenA family. Type 1 subfamily
C7M28_02027	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_02028	COG1696	Membrane protein involved in D-alanine export
C7M28_02029	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M28_02030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M28_02031	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7M28_02032	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M28_02033	COG1486	melibiose metabolic process
C7M28_02034	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M28_02035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M28_02036	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M28_02037	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M28_02037	COG3711	transcriptional antiterminator
C7M28_02039	COG2094	Belongs to the DNA glycosylase MPG family
C7M28_02040	COG0753	catalase activity
C7M28_02041	COG2814	Major facilitator Superfamily
C7M28_02042	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M28_02043	COG1131	(ABC) transporter
C7M28_02047	COG1595	DNA-templated transcription, initiation
C7M28_02048	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M28_02049	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M28_02050	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M28_02051	COG4988	ABC transporter
C7M28_02052	COG1294	oxidase, subunit
C7M28_02053	COG1271	oxidase subunit
C7M28_02054	COG3493	citrate carrier protein
C7M28_02055	COG0501	Belongs to the peptidase M48B family
C7M28_02057	COG0726	polysaccharide deacetylase
C7M28_02058	COG3842	ATPase activity
C7M28_02059	COG2508	Transcriptional regulator
C7M28_02060	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_02061	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M28_02063	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M28_02065	COG4585	Histidine kinase
C7M28_02066	COG2197	response regulator
C7M28_02067	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M28_02069	COG4894	glucomannan catabolic process
C7M28_02070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M28_02071	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M28_02072	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_02073	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M28_02074	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M28_02075	COG2610	gluconate transmembrane transporter activity
C7M28_02076	COG0500	methyltransferase
C7M28_02077	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M28_02080	COG0753	catalase activity
C7M28_02080	COG0693	protein deglycase activity
C7M28_02081	COG2851	Citrate transporter
C7M28_02082	COG2273	Hydrolase Family 16
C7M28_02083	COG3711	transcriptional antiterminator
C7M28_02085	COG2270	Major facilitator Superfamily
C7M28_02086	COG0513	Belongs to the DEAD box helicase family
C7M28_02087	COG3401	FG-GAP repeat protein
C7M28_02087	COG2755	lipolytic protein G-D-S-L family
C7M28_02098	COG3209	COG3209 Rhs family protein
C7M28_02099	COG0697	spore germination
C7M28_02100	COG0589	response to stress
C7M28_02101	COG2723	6-phospho-beta-galactosidase activity
C7M28_02102	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M28_02102	COG2190	(PTS) system
C7M28_02102	COG1263	PTS System
C7M28_02105	COG5444	nuclease activity
C7M28_02108	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M28_02110	COG2986	histidine ammonia-lyase
C7M28_02111	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C7M28_02112	COG1228	amidohydrolase
C7M28_02113	COG0010	Belongs to the arginase family
C7M28_02114	COG0833	amino acid
C7M28_02115	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7M28_02116	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M28_02117	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7M28_02118	COG2390	Transcriptional regulator
C7M28_02120	COG3192	ethanolamine utilization protein
C7M28_02121	COG2079	MmgE PrpD family protein
C7M28_02122	COG1473	amidohydrolase
C7M28_02123	COG1126	abc transporter atp-binding protein
C7M28_02124	COG0765	amino acid transport
C7M28_02125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M28_02126	COG0456	acetyltransferase
C7M28_02127	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M28_02129	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M28_02130	COG0561	phosphatase activity
C7M28_02136	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M28_02137	COG5294	Protein conserved in bacteria
C7M28_02138	COG0577	efflux transmembrane transporter activity
C7M28_02139	COG1136	(ABC) transporter
C7M28_02140	COG2205	protein histidine kinase activity
C7M28_02141	COG0745	RESPONSE REGULATOR receiver
C7M28_02142	COG0191	fructose-bisphosphate aldolase activity
C7M28_02143	COG1082	Xylose isomerase domain protein TIM barrel
C7M28_02144	COG1082	Xylose isomerase domain protein TIM barrel
C7M28_02145	COG0673	inositol 2-dehydrogenase activity
C7M28_02146	COG2814	Major facilitator Superfamily
C7M28_02147	COG1082	Xylose isomerase domain protein TIM barrel
C7M28_02148	COG3962	Belongs to the TPP enzyme family
C7M28_02149	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M28_02151	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_02152	COG1349	DNA-binding transcription factor activity
C7M28_02153	COG0667	Aldo Keto reductase
C7M28_02156	COG2814	Major facilitator Superfamily
C7M28_02157	COG0326	Molecular chaperone. Has ATPase activity
C7M28_02159	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_02160	COG1309	transcriptional regulator
C7M28_02161	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_02162	COG0456	acetyltransferase
C7M28_02163	COG2850	peptidyl-arginine hydroxylation
C7M28_02164	COG2226	methyltransferase
C7M28_02167	COG0367	asparagine synthase
C7M28_02168	COG2814	Major facilitator Superfamily
C7M28_02169	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7M28_02171	COG1714	RDD family
C7M28_02172	COG2311	Membrane
C7M28_02173	COG1917	Cupin 2, conserved barrel domain protein
C7M28_02174	COG1309	transcriptional regulator
C7M28_02175	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_02176	COG1846	Transcriptional regulator
C7M28_02177	COG1380	Effector of murein hydrolase LrgA
C7M28_02178	COG1346	cytolysis
C7M28_02179	COG5039	Polysaccharide pyruvyl transferase
C7M28_02180	COG1929	Belongs to the glycerate kinase type-1 family
C7M28_02181	COG1802	Transcriptional regulator
C7M28_02182	COG1070	Carbohydrate kinase
C7M28_02183	COG2610	gluconate transmembrane transporter activity
C7M28_02184	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M28_02185	COG0450	alkyl hydroperoxide reductase
C7M28_02186	COG3634	alkyl hydroperoxide reductase activity
C7M28_02187	COG2723	6-phospho-beta-galactosidase activity
C7M28_02188	COG2190	(PTS) system
C7M28_02189	COG2188	Transcriptional regulator
C7M28_02191	COG1131	(ABC) transporter
C7M28_02192	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C7M28_02195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7M28_02198	COG1063	alcohol dehydrogenase
C7M28_02202	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C7M28_02203	COG0456	acetyltransferase
C7M28_02204	COG0457	Tetratricopeptide repeat
C7M28_02206	COG0010	Belongs to the arginase family
C7M28_02207	COG0833	amino acid
C7M28_02208	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M28_02212	COG5658	integral membrane protein
C7M28_02213	COG0640	Transcriptional regulator
C7M28_02214	COG3829	transcription factor binding
C7M28_02215	COG5002	protein histidine kinase activity
C7M28_02219	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M28_02220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M28_02221	COG4853	Protein conserved in bacteria
C7M28_02222	COG4863	YycH protein
C7M28_02223	COG5002	protein histidine kinase activity
C7M28_02224	COG0745	RESPONSE REGULATOR receiver
C7M28_02230	COG0346	lactoylglutathione lyase activity
C7M28_02231	COG0305	Participates in initiation and elongation during chromosome replication
C7M28_02234	COG3093	addiction module antidote protein HigA
C7M28_02235	COG2807	transmembrane transport
C7M28_02236	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M28_02237	COG0359	binds to the 23S rRNA
C7M28_02238	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7M28_02239	COG4241	membrane
C7M28_02241	COG5577	PFAM Coat F domain
C7M28_02242	COG1733	regulation of RNA biosynthetic process
C7M28_02243	COG1227	inorganic diphosphatase activity
C7M28_02246	COG2271	Major facilitator Superfamily
C7M28_02247	COG4978	Transcriptional regulator
C7M28_02247	COG0789	Transcriptional regulator
C7M28_02249	COG4319	ketosteroid isomerase
C7M28_02250	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M28_02251	COG2814	Major facilitator Superfamily
C7M28_02252	COG0583	DNA-binding transcription factor activity
C7M28_02253	COG2153	protein acetylation
C7M28_02255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M28_02256	COG1846	Transcriptional regulator
C7M28_02257	COG2153	protein acetylation
C7M28_02258	COG2364	Membrane
C7M28_02259	COG0456	acetyltransferase
C7M28_02260	COG2315	Protein conserved in bacteria
C7M28_02261	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M28_02262	COG2814	Major facilitator Superfamily
C7M28_02263	COG1331	Highly conserved protein containing a thioredoxin domain
C7M28_02264	COG0789	Transcriptional regulator
C7M28_02265	COG0697	spore germination
C7M28_02266	COG1331	Highly conserved protein containing a thioredoxin domain
C7M28_02271	COG0791	NLP P60 protein
C7M28_02271	COG0741	lytic transglycosylase activity
C7M28_02272	COG5644	endopeptidase inhibitor activity
C7M28_02274	COG0433	COG0433 Predicted ATPase
C7M28_02284	COG2946	Replication initiation factor
C7M28_02285	COG1674	ftsk spoiiie
C7M28_02289	COG1396	sequence-specific DNA binding
C7M28_02290	COG2856	Zn peptidase
C7M28_02291	COG0457	Tetratricopeptide repeat
C7M28_02293	COG1331	Highly conserved protein containing a thioredoxin domain
C7M28_02296	COG1331	Highly conserved protein containing a thioredoxin domain
C7M28_02297	COG1331	Highly conserved protein containing a thioredoxin domain
C7M28_02298	COG1266	CAAX protease self-immunity
C7M28_02299	COG0477	Major facilitator Superfamily
C7M28_02299	COG2814	Major facilitator Superfamily
C7M28_02300	COG0110	maltose O-acetyltransferase activity
C7M28_02301	COG0346	lactoylglutathione lyase activity
C7M28_02302	COG1609	Transcriptional regulator
C7M28_02303	COG0708	Exodeoxyribonuclease III
C7M28_02304	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7M28_02305	COG0629	single-stranded DNA binding
C7M28_02306	COG0360	Binds together with S18 to 16S ribosomal RNA
C7M28_02307	COG0012	GTP binding
C7M28_02308	COG0243	molybdopterin cofactor binding
C7M28_02309	COG4481	Protein conserved in bacteria
C7M28_02310	COG3949	Membrane
C7M28_02312	COG1475	DNA binding
C7M28_02313	COG1192	Involved in chromosome partitioning
C7M28_02315	COG1475	DNA binding
C7M28_02316	COG0357	Ribosomal RNA small subunit methyltransferase G
C7M28_02317	COG0445	tRNA wobble uridine modification
C7M28_02318	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7M28_02319	COG1847	R3H domain protein
C7M28_02320	COG0706	membrane insertase activity
C7M28_02321	COG0594	ribonuclease P activity
C7M28_02322	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7M28_02323	COG0592	DNA-directed DNA polymerase activity
C7M28_02324	COG2501	S4 domain
C7M28_02325	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7M28_02327	COG0187	DNA topoisomerase II activity
C7M28_02328	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M28_02335	COG0516	GMP reductase activity
C7M28_02335	COG0517	IMP dehydrogenase activity
C7M28_02336	COG1686	Belongs to the peptidase S11 family
C7M28_02337	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C7M28_02338	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C7M28_02339	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M28_02341	COG1428	Deoxynucleoside kinase
C7M28_02342	COG1428	Deoxynucleoside kinase
C7M28_02343	COG1388	LysM domain
C7M28_02343	COG3858	chitin binding
C7M28_02344	COG1335	isochorismatase
C7M28_02345	COG0590	tRNA wobble adenosine to inosine editing
C7M28_02346	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M28_02347	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M28_02348	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7M28_02357	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C7M28_02358	COG3853	Toxic anion resistance protein (TelA)
C7M28_02359	COG1982	Orn Lys Arg decarboxylase major
C7M28_02360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M28_02361	COG3870	Protein conserved in bacteria
C7M28_02362	COG1728	Protein conserved in bacteria
C7M28_02363	COG0470	DNA polymerase III
C7M28_02364	COG1774	PSP1 C-terminal conserved region
C7M28_02365	COG4467	Involved in initiation control of chromosome replication
C7M28_02366	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M28_02367	COG2827	Endonuclease containing a URI domain
C7M28_02368	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7M28_02369	COG2002	toxin-antitoxin pair type II binding
C7M28_02370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M28_02370	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M28_02371	COG0084	hydrolase, TatD family'
C7M28_02372	COG3583	domain protein
C7M28_02372	COG3584	3D domain protein
C7M28_02373	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M28_02374	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M28_02376	COG4466	Protein conserved in bacteria
C7M28_02378	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7M28_02379	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M28_02380	COG0251	oxidation-reduction process
C7M28_02381	COG2088	sporulation resulting in formation of a cellular spore
C7M28_02382	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7M28_02383	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M28_02384	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7M28_02385	COG0193	aminoacyl-tRNA hydrolase activity
C7M28_02387	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M28_02388	COG2002	toxin-antitoxin pair type II binding
C7M28_02389	COG2244	polysaccharide biosynthetic process
C7M28_02390	COG3956	TIGRFAM MazG family protein
C7M28_02391	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M28_02394	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7M28_02395	COG1098	S1 RNA binding domain
C7M28_02398	COG2208	phosphoserine phosphatase activity
C7M28_02399	COG2304	oxidoreductase activity
C7M28_02400	COG0515	serine threonine protein kinase
C7M28_02401	COG0037	tRNA processing
C7M28_02403	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M28_02404	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C7M28_02405	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7M28_02406	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M28_02407	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M28_02408	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M28_02409	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M28_02410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M28_02411	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7M28_02412	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7M28_02413	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M28_02414	COG1396	sequence-specific DNA binding
C7M28_02415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M28_02416	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M28_02432	COG4463	regulation of RNA biosynthetic process
C7M28_02433	COG3880	PFAM UvrB UvrC protein
C7M28_02434	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C7M28_02435	COG0542	response to heat
C7M28_02436	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7M28_02437	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C7M28_02438	COG4956	integral membrane protein (PIN domain superfamily)
C7M28_02439	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7M28_02440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7M28_02441	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7M28_02442	COG1045	serine acetyltransferase
C7M28_02443	COG0215	cysteine-tRNA ligase activity
C7M28_02444	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M28_02445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M28_02446	COG3688	RNA-binding protein containing a PIN domain
C7M28_02447	COG1595	DNA-templated transcription, initiation
C7M28_02448	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M28_02449	COG0250	Participates in transcription elongation, termination and antitermination
C7M28_02451	COG0081	regulation of translation
C7M28_02452	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7M28_02454	COG2813	Specifically methylates the guanine in position
C7M28_02455	COG0085	RNA polymerase activity
C7M28_02456	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7M28_02457	COG1358	cellular component organization or biogenesis
C7M28_02458	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7M28_02459	COG0049	tRNA binding
C7M28_02460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7M28_02461	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7M28_02462	COG0596	Alpha beta hydrolase
C7M28_02464	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7M28_02465	COG0088	Forms part of the polypeptide exit tunnel
C7M28_02467	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7M28_02471	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M28_02473	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7M28_02474	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7M28_02476	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7M28_02478	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7M28_02479	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7M28_02480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7M28_02483	COG0200	Binds to the 23S rRNA
C7M28_02484	COG0201	protein transport
C7M28_02485	COG0563	adenylate kinase activity
C7M28_02486	COG0024	Methionine aminopeptidase
C7M28_02488	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M28_02489	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7M28_02490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7M28_02491	COG0202	RNA polymerase activity
C7M28_02492	COG0203	ribosomal protein L17
C7M28_02493	COG1122	ATPase activity
C7M28_02494	COG1122	ATPase activity
C7M28_02495	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M28_02496	COG0101	tRNA pseudouridine synthase activity
C7M28_02497	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7M28_02498	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7M28_02499	COG2226	methyltransferase
C7M28_02501	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M28_02502	COG0489	protein tyrosine kinase activity
C7M28_02504	COG2194	sulfuric ester hydrolase activity
C7M28_02505	COG0726	polysaccharide deacetylase
C7M28_02521	COG0659	secondary active sulfate transmembrane transporter activity
C7M28_02523	COG0385	Bile acid
C7M28_02524	COG2819	hydrolase of the alpha beta superfamily
C7M28_02525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M28_02526	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M28_02527	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M28_02528	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M28_02528	COG2207	Transcriptional regulator
C7M28_02529	COG3876	Protein conserved in bacteria
C7M28_02530	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M28_02531	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M28_02532	COG1263	PTS System
C7M28_02532	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M28_02533	COG1737	Transcriptional regulator
C7M28_02534	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M28_02535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M28_02536	COG1683	Conserved Protein
C7M28_02542	COG1595	DNA-templated transcription, initiation
C7M28_02543	COG5662	AntiSigma factor
C7M28_02544	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M28_02545	COG4856	YbbR-like protein
C7M28_02546	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M28_02547	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M28_02548	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M28_02549	COG2169	Transcriptional regulator
C7M28_02550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M28_02551	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M28_02552	COG3002	Belongs to the UPF0753 family
C7M28_02553	COG0288	reversible hydration of carbon dioxide
C7M28_02556	COG5609	conserved protein (DUF2294)
C7M28_02557	COG0640	Transcriptional regulator
C7M28_02558	COG2814	Major facilitator Superfamily
C7M28_02560	COG0535	radical SAM domain protein
C7M28_02561	COG1266	CAAX protease self-immunity
C7M28_02562	COG1131	(ABC) transporter
C7M28_02564	COG1413	lyase activity
C7M28_02565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M28_02566	COG0596	Alpha beta hydrolase
C7M28_02567	COG0745	RESPONSE REGULATOR receiver
C7M28_02568	COG0642	Histidine kinase
C7M28_02570	COG0515	serine threonine protein kinase
C7M28_02573	COG1113	amino acid transport
C7M28_02576	COG2602	Beta-lactamase
C7M28_02577	COG2124	cytochrome p450
C7M28_02579	COG0531	amino acid
C7M28_02580	COG0584	glycerophosphoryl diester phosphodiesterase
C7M28_02581	COG2271	Major facilitator Superfamily
C7M28_02583	COG1846	Transcriptional regulator
C7M28_02583	COG0456	acetyltransferase
C7M28_02584	COG2271	Major facilitator Superfamily
C7M28_02587	COG3409	Peptidoglycan-binding domain 1 protein
C7M28_02588	COG0697	spore germination
C7M28_02589	COG2207	Transcriptional regulator
C7M28_02589	COG1917	Cupin 2, conserved barrel domain protein
C7M28_02590	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7M28_02591	COG3591	Belongs to the peptidase S1B family
C7M28_02593	COG0596	Alpha beta hydrolase
C7M28_02594	COG1183	phosphatidylcholine synthase activity
C7M28_02595	COG0586	Pfam SNARE associated Golgi protein
C7M28_02596	COG0688	phosphatidylethanolamine metabolic process
C7M28_02598	COG2312	Erythromycin esterase
C7M28_02600	COG1301	dicarboxylic acid transport
C7M28_02601	COG1263	PTS System
C7M28_02601	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M28_02601	COG2190	(PTS) system
C7M28_02602	COG0363	glucosamine-6-phosphate deaminase activity
C7M28_02603	COG2188	Transcriptional regulator
C7M28_02605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M28_02606	COG0833	amino acid
C7M28_02607	COG2040	homocysteine
C7M28_02608	COG1115	amino acid carrier protein
C7M28_02609	COG2066	Belongs to the glutaminase family
C7M28_02610	COG4191	Histidine kinase
C7M28_02611	COG0784	Response regulator, receiver
C7M28_02612	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M28_02613	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_02614	COG2271	Major facilitator Superfamily
C7M28_02615	COG4948	Mandelate Racemase Muconate Lactonizing
C7M28_02616	COG2186	Transcriptional regulator
C7M28_02617	COG2721	sulfolactate sulfo-lyase activity
C7M28_02618	COG3173	Aminoglycoside phosphotransferase
C7M28_02620	COG0697	spore germination
C7M28_02621	COG0745	RESPONSE REGULATOR receiver
C7M28_02622	COG2205	protein histidine kinase activity
C7M28_02623	COG1131	(ABC) transporter
C7M28_02626	COG3773	Cell wall hydrolase
C7M28_02627	COG2304	oxidoreductase activity
C7M28_02628	COG3540	Alkaline phosphatase
C7M28_02629	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M28_02630	COG0805	protein transport
C7M28_02631	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7M28_02632	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M28_02633	COG0477	Major facilitator Superfamily
C7M28_02634	COG1309	transcriptional regulator
C7M28_02635	COG0252	asparaginase activity
C7M28_02636	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M28_02637	COG1714	RDD family
C7M28_02638	COG3012	SEC-C Motif Domain Protein
C7M28_02638	COG1405	negative regulation of cell septum assembly
C7M28_02639	COG3290	protein histidine kinase activity
C7M28_02640	COG3279	Response regulator of the LytR AlgR family
C7M28_02641	COG4555	ABC transporter
C7M28_02642	COG1668	transmembrane transport
C7M28_02643	COG0667	Aldo Keto reductase
C7M28_02644	COG0667	Aldo Keto reductase
C7M28_02646	COG1595	DNA-templated transcription, initiation
C7M28_02647	COG1595	DNA-templated transcription, initiation
C7M28_02648	COG1876	peptidase activity
C7M28_02649	COG0457	Tetratricopeptide repeat
C7M28_02650	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_02651	COG0366	Alpha amylase catalytic
C7M28_02652	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M28_02653	COG1121	(ABC) transporter
C7M28_02654	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M28_02655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M28_02656	COG2310	stress, protein
C7M28_02657	COG2310	stress, protein
C7M28_02658	COG2310	stress, protein
C7M28_02659	COG0861	Integral membrane protein TerC family
C7M28_02661	COG3853	Toxic anion resistance protein (TelA)
C7M28_02662	COG0477	Major facilitator Superfamily
C7M28_02663	COG2814	Major facilitator Superfamily
C7M28_02664	COG0640	Transcriptional regulator
C7M28_02665	COG0517	IMP dehydrogenase activity
C7M28_02665	COG4175	Glycine betaine
C7M28_02666	COG4176	ABC-type proline glycine betaine transport system permease component
C7M28_02667	COG2113	Glycine betaine
C7M28_02668	COG1473	amidohydrolase
C7M28_02669	COG1288	antiporter activity
C7M28_02671	COG0366	Alpha amylase catalytic
C7M28_02672	COG0039	L-malate dehydrogenase activity
C7M28_02673	COG1620	l-lactate permease
C7M28_02674	COG2814	Major facilitator Superfamily
C7M28_02675	COG1846	Transcriptional regulator
C7M28_02676	COG1280	lysine exporter protein (LysE YggA)
C7M28_02677	COG3403	YqcI/YcgG family
C7M28_02678	COG1113	amino acid transport
C7M28_02679	COG3665	Urea carboxylase-associated protein
C7M28_02680	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7M28_02681	COG1660	Displays ATPase and GTPase activities
C7M28_02683	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M28_02684	COG2226	methyltransferase
C7M28_02685	COG0583	DNA-binding transcription factor activity
C7M28_02686	COG3458	cephalosporin-C deacetylase activity
C7M28_02687	COG3541	Predicted nucleotidyltransferase
C7M28_02688	COG0506	proline dehydrogenase activity
C7M28_02689	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_02690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M28_02691	COG2508	Transcriptional regulator
C7M28_02692	COG3689	TIGRFAM TIGR03943 family protein
C7M28_02693	COG0701	Predicted permease
C7M28_02694	COG2267	carboxylic ester hydrolase activity
C7M28_02695	COG0492	ferredoxin-NADP+ reductase activity
C7M28_02696	COG1587	Uroporphyrinogen-III synthase
C7M28_02696	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M28_02697	COG2146	nitrite reductase [NAD(P)H] activity
C7M28_02698	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M28_02699	COG0243	molybdopterin cofactor binding
C7M28_02700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M28_02701	COG2223	nitrite transmembrane transporter activity
C7M28_02702	COG1469	GTP cyclohydrolase I activity
C7M28_02703	COG1376	ErfK ybiS ycfS ynhG family protein
C7M28_02704	COG0523	cobalamin synthesis protein
C7M28_02705	COG0765	amino acid transport
C7M28_02706	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M28_02709	COG1714	RDD family
C7M28_02711	COG2723	6-phospho-beta-galactosidase activity
C7M28_02713	COG3209	COG3209 Rhs family protein
C7M28_02714	COG3290	protein histidine kinase activity
C7M28_02714	COG0840	transmembrane signaling receptor activity
C7M28_02715	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M28_02716	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7M28_02717	COG1733	regulation of RNA biosynthetic process
C7M28_02718	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_02719	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_02720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_02721	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7M28_02722	COG2814	Major facilitator Superfamily
C7M28_02724	COG0697	spore germination
C7M28_02725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M28_02727	COG2364	Membrane
C7M28_02728	COG1126	abc transporter atp-binding protein
C7M28_02729	COG0765	amino acid transport
C7M28_02730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M28_02731	COG0583	DNA-binding transcription factor activity
C7M28_02732	COG0163	prenyltransferase activity
C7M28_02733	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M28_02736	COG0596	Alpha beta hydrolase
C7M28_02737	COG3104	oligopeptide transport
C7M28_02738	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M28_02740	COG0697	spore germination
C7M28_02742	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M28_02743	COG1136	(ABC) transporter
C7M28_02744	COG0577	efflux transmembrane transporter activity
C7M28_02745	COG0745	RESPONSE REGULATOR receiver
C7M28_02746	COG5002	protein histidine kinase activity
C7M28_02746	COG3850	Histidine kinase
C7M28_02747	COG0457	Tetratricopeptide repeat
C7M28_02750	COG0527	aspartate kinase activity
C7M28_02751	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M28_02752	COG4605	iron ion homeostasis
C7M28_02753	COG4604	ABC transporter, ATP-binding protein
C7M28_02754	COG4607	ABC-type enterochelin transport system periplasmic component
C7M28_02755	COG2814	Major facilitator Superfamily
C7M28_02756	COG1309	transcriptional regulator
C7M28_02757	COG0778	Nitroreductase
C7M28_02758	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M28_02759	COG0640	Transcriptional regulator
C7M28_02760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M28_02761	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M28_02762	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_02763	COG4975	Glucose uptake
C7M28_02764	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_02765	COG4549	nuclear export factor GLE1
C7M28_02766	COG1276	copper resistance
C7M28_02766	COG2372	response to copper ion
C7M28_02767	COG1349	DNA-binding transcription factor activity
C7M28_02769	COG2213	PTS system mannitol-specific
C7M28_02770	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M28_02771	COG0246	Mannitol dehydrogenase
C7M28_02772	COG0473	3-isopropylmalate dehydrogenase activity
C7M28_02774	COG0681	Belongs to the peptidase S26 family
C7M28_02775	COG0412	Dienelactone hydrolase
C7M28_02776	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M28_02778	COG0561	phosphatase activity
C7M28_02779	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C7M28_02780	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M28_02781	COG4336	lyase activity
C7M28_02782	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7M28_02783	COG1984	allophanate hydrolase subunit 2
C7M28_02784	COG1414	Transcriptional regulator
C7M28_02785	COG2755	lipolytic protein G-D-S-L family
C7M28_02787	COG2329	Antibiotic biosynthesis monooxygenase
C7M28_02788	COG0768	penicillin binding
C7M28_02789	COG4989	oxidoreductase activity
C7M28_02790	COG3711	transcriptional antiterminator
C7M28_02791	COG0318	PFAM AMP-dependent synthetase and ligase
C7M28_02792	COG2226	methyltransferase
C7M28_02793	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_02794	COG1917	Cupin 2, conserved barrel domain protein
C7M28_02795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M28_02796	COG3871	stress protein (general stress protein 26)
C7M28_02798	COG2814	Major facilitator Superfamily
C7M28_02799	COG1522	sequence-specific DNA binding
C7M28_02800	COG0551	DNA topoisomerase type I activity
C7M28_02800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M28_02801	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C7M28_02802	COG3706	GGDEF domain
C7M28_02803	COG5298	Protein conserved in bacteria
C7M28_02804	COG1215	transferase activity, transferring glycosyl groups
C7M28_02806	COG0531	amino acid
C7M28_02807	COG0494	nUDIX hydrolase
C7M28_02808	COG0028	Belongs to the TPP enzyme family
C7M28_02810	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M28_02811	COG2261	transglycosylase associated protein
C7M28_02812	COG4876	unkown
C7M28_02813	COG2217	Heavy metal translocating P-type atpase
C7M28_02814	COG3729	General stress protein
C7M28_02815	COG0662	Cupin 2, conserved barrel domain protein
C7M28_02816	COG2329	Antibiotic biosynthesis monooxygenase
C7M28_02817	COG3546	catalase activity
C7M28_02818	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7M28_02819	COG3290	protein histidine kinase activity
C7M28_02820	COG4565	transcriptional regulatory protein
C7M28_02821	COG1301	dicarboxylic acid transport
C7M28_02822	COG0628	permease
C7M28_02823	COG1131	(ABC) transporter
C7M28_02824	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M28_02826	COG1960	acyl-CoA dehydrogenase activity
C7M28_02829	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M28_02830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M28_02831	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M28_02832	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M28_02833	COG0513	Belongs to the DEAD box helicase family
C7M28_02834	COG3402	PFAM membrane-flanked domain
C7M28_02835	COG3428	Bacterial PH domain
C7M28_02836	COG0705	Rhomboid family
C7M28_02837	COG0736	holo-[acyl-carrier-protein] synthase activity
C7M28_02838	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7M28_02839	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M28_02840	COG0864	Transcriptional regulator
C7M28_02841	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M28_02842	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M28_02843	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M28_02844	COG2172	sigma factor antagonist activity
C7M28_02845	COG2208	phosphoserine phosphatase activity
C7M28_02846	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M28_02847	COG2172	sigma factor antagonist activity
C7M28_02848	COG1191	sigma factor activity
C7M28_02849	COG2208	phosphoserine phosphatase activity
C7M28_02853	COG1673	EVE domain
C7M28_02854	COG1846	Transcriptional regulator
C7M28_02855	COG2183	response to ionizing radiation
C7M28_02856	COG3091	SprT-like family
C7M28_02864	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M28_02866	COG5444	nuclease activity
C7M28_02867	COG1476	TRANSCRIPTIONal
C7M28_02872	COG0693	protein deglycase activity
C7M28_02873	COG1278	Cold shock
C7M28_02874	COG1329	Transcriptional regulator
C7M28_02875	COG0697	spore germination
C7M28_02876	COG1917	Cupin 2, conserved barrel domain protein
C7M28_02876	COG2207	Transcriptional regulator
C7M28_02877	COG0697	spore germination
C7M28_02878	COG3708	Transcriptional regulator
C7M28_02878	COG2207	Transcriptional regulator
C7M28_02879	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M28_02880	COG0477	Major facilitator Superfamily
C7M28_02882	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C7M28_02885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M28_02886	COG1309	transcriptional regulator
C7M28_02887	COG0697	spore germination
C7M28_02888	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M28_02889	COG2030	dehydratase
C7M28_02890	COG3545	Serine hydrolase
C7M28_02891	COG1733	regulation of RNA biosynthetic process
C7M28_02892	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M28_02893	COG1733	regulation of RNA biosynthetic process
C7M28_02894	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M28_02895	COG2814	Major facilitator Superfamily
C7M28_02896	COG1309	transcriptional regulator
C7M28_02897	COG0640	Transcriptional regulator
C7M28_02898	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M28_02899	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M28_02900	COG0697	spore germination
C7M28_02901	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M28_02902	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M28_02903	COG0640	Transcriptional regulator
C7M28_02904	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M28_02906	COG4585	Histidine kinase
C7M28_02907	COG2197	response regulator
C7M28_02908	COG2409	Drug exporters of the RND superfamily
C7M28_02909	COG0596	Alpha beta hydrolase
C7M28_02910	COG1811	Na channel or pump
C7M28_02911	COG0789	Transcriptional regulator
C7M28_02911	COG4978	Transcriptional regulator
C7M28_02912	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M28_02913	COG0778	Nitroreductase
C7M28_02914	COG0346	lactoylglutathione lyase activity
C7M28_02915	COG2259	Doxx family
C7M28_02916	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M28_02920	COG2323	membrane
C7M28_02921	COG2323	membrane
C7M28_02922	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M28_02925	COG1309	transcriptional regulator
C7M28_02927	COG0456	acetyltransferase
C7M28_02928	COG0673	inositol 2-dehydrogenase activity
C7M28_02929	COG1609	Transcriptional regulator
C7M28_02930	COG2814	Major facilitator Superfamily
C7M28_02931	COG1082	Xylose isomerase domain protein TIM barrel
C7M28_02933	COG1113	amino acid transport
C7M28_02934	COG2318	DinB family
C7M28_02935	COG1846	Transcriptional regulator
C7M28_02936	COG1033	growth of symbiont in host cell
C7M28_02936	COG2409	Drug exporters of the RND superfamily
C7M28_02937	COG0778	Nitroreductase
C7M28_02938	COG1846	Transcriptional regulator
C7M28_02939	COG2814	Major facilitator Superfamily
C7M28_02940	COG0730	response to heat
C7M28_02941	COG1802	Transcriptional regulator
C7M28_02942	COG3858	chitin binding
C7M28_02942	COG1388	LysM domain
C7M28_02943	COG1819	glycosyl
C7M28_02945	COG1785	Belongs to the alkaline phosphatase family
C7M28_02946	COG5646	InterPro IPR014922
C7M28_02948	COG0454	-acetyltransferase
C7M28_02949	COG1078	dGTPase activity
C7M28_02950	COG1388	LysM domain
C7M28_02951	COG2814	Major facilitator Superfamily
C7M28_02952	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M28_02953	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M28_02954	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M28_02955	COG2723	6-phospho-beta-galactosidase activity
C7M28_02956	COG2188	Transcriptional regulator
C7M28_02957	COG1940	carbohydrate kinase activity
C7M28_02958	COG1482	cell wall glycoprotein biosynthetic process
C7M28_02959	COG4124	Belongs to the glycosyl hydrolase 26 family
C7M28_02968	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7M28_02969	COG0802	atpase or kinase
C7M28_02970	COG1214	PFAM Peptidase M22, glycoprotease
C7M28_02971	COG0456	acetyltransferase
C7M28_02972	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M28_02973	COG0488	(ABC) transporter
C7M28_02974	COG0315	cyclic pyranopterin monophosphate synthase activity
C7M28_02975	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7M28_02976	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M28_02977	COG0805	protein transport
C7M28_02979	COG1266	CAAX protease self-immunity
C7M28_02981	COG0459	protein refolding
C7M28_02983	COG3378	Phage plasmid primase P4 family
C7M28_02984	COG0270	DNA (cytosine-5-)-methyltransferase activity
C7M28_02985	COG0270	DNA (cytosine-5-)-methyltransferase activity
C7M28_02987	COG1401	restriction endodeoxyribonuclease activity
C7M28_02990	COG0457	Tetratricopeptide repeat
C7M28_02991	COG1063	alcohol dehydrogenase
C7M28_02992	COG2211	Major facilitator Superfamily
C7M28_02993	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M28_02994	COG1842	Phage shock protein A
C7M28_02995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M28_02996	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7M28_02997	COG4260	virion core protein, lumpy skin disease virus
C7M28_02999	COG2814	Major facilitator Superfamily
C7M28_03000	COG1063	alcohol dehydrogenase
C7M28_03001	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7M28_03002	COG0823	Involved in the tonB-independent uptake of proteins
C7M28_03005	COG2267	carboxylic ester hydrolase activity
C7M28_03007	COG2132	Multicopper oxidase
C7M28_03008	COG1113	amino acid transport
C7M28_03009	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M28_03010	COG0714	Associated with various cellular activities
C7M28_03011	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C7M28_03012	COG1305	Transglutaminase-like
C7M28_03013	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7M28_03013	COG0519	Catalyzes the synthesis of GMP from XMP
C7M28_03016	COG2252	PERMEase
C7M28_03017	COG3064	Membrane
C7M28_03019	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C7M28_03021	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7M28_03022	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M28_03023	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M28_03024	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M28_03025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M28_03026	COG0047	phosphoribosylformylglycinamidine synthase activity
C7M28_03027	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M28_03028	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7M28_03029	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7M28_03030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M28_03031	COG0138	bifunctional purine biosynthesis protein purh
C7M28_03032	COG0151	Belongs to the GarS family
C7M28_03033	COG1522	sequence-specific DNA binding
C7M28_03034	COG0531	amino acid
C7M28_03036	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M28_03037	COG1470	cell adhesion involved in biofilm formation
C7M28_03038	COG4496	protein, YerC YecD
C7M28_03039	COG0069	glutamate synthase activity
C7M28_03040	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C7M28_03041	COG0210	DNA helicase
C7M28_03042	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7M28_03043	COG4851	CamS sex pheromone cAM373 precursor
C7M28_03044	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M28_03045	COG1285	pathogenesis
C7M28_03046	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M28_03047	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M28_03048	COG0154	amidase activity
C7M28_03049	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M28_03050	COG1309	transcriptional regulator
C7M28_03051	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7M28_03052	COG1597	lipid kinase activity
C7M28_03053	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M28_03058	COG0457	Tetratricopeptide repeat
C7M28_03062	COG5444	nuclease activity
C7M28_03064	COG3586	endonuclease activity
C7M28_03065	COG3391	amine dehydrogenase activity
C7M28_03066	COG3391	amine dehydrogenase activity
C7M28_03068	COG0457	Tetratricopeptide repeat
C7M28_03070	COG0217	transcriptional regulatory protein
C7M28_03072	COG1309	transcriptional regulator
C7M28_03073	COG3631	Ketosteroid isomerase-related protein
C7M28_03074	COG0702	epimerase
C7M28_03077	COG3546	catalase activity
C7M28_03078	COG0454	-acetyltransferase
C7M28_03079	COG5578	integral membrane protein
C7M28_03080	COG2972	Histidine kinase
C7M28_03081	COG2207	Transcriptional regulator
C7M28_03081	COG4753	response regulator
C7M28_03082	COG1653	transport
C7M28_03083	COG1175	transmembrane transport
C7M28_03084	COG0395	ABC-type sugar transport system, permease component
C7M28_03085	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M28_03086	COG2207	Transcriptional regulator
C7M28_03087	COG2755	lipolytic protein G-D-S-L family
C7M28_03089	COG5578	integral membrane protein
C7M28_03090	COG3401	FG-GAP repeat protein
C7M28_03091	COG3401	FG-GAP repeat protein
C7M28_03092	COG2755	lipolytic protein G-D-S-L family
C7M28_03093	COG1874	Beta-galactosidase
C7M28_03095	COG1653	transport
C7M28_03096	COG4209	transmembrane transport
C7M28_03097	COG0395	ABC-type sugar transport system, permease component
C7M28_03098	COG1486	melibiose metabolic process
C7M28_03099	COG2323	membrane
C7M28_03100	COG2329	Antibiotic biosynthesis monooxygenase
C7M28_03101	COG0346	lactoylglutathione lyase activity
C7M28_03104	COG5583	Uncharacterized small protein (DUF2292)
C7M28_03105	COG0670	Belongs to the BI1 family
C7M28_03106	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M28_03108	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M28_03108	COG2124	cytochrome p450
C7M28_03109	COG1368	sulfuric ester hydrolase activity
C7M28_03110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7M28_03111	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M28_03112	COG1442	glycosyl transferase family 8
C7M28_03113	COG1216	Glycosyl transferase, family 2
C7M28_03114	COG1442	glycosyl transferase family 8
C7M28_03115	COG2223	nitrite transmembrane transporter activity
C7M28_03116	COG1011	Hydrolase
C7M28_03117	COG0531	amino acid
C7M28_03118	COG1012	belongs to the aldehyde dehydrogenase family
C7M28_03119	COG0840	transmembrane signaling receptor activity
C7M28_03120	COG0488	(ABC) transporter
C7M28_03122	COG0789	Transcriptional regulator
C7M28_03123	COG2814	Major facilitator Superfamily
C7M28_03124	COG0488	(ABC) transporter
C7M28_03125	COG0513	Belongs to the DEAD box helicase family
C7M28_03126	COG0456	acetyltransferase
C7M28_03127	COG2130	NADP-dependent
C7M28_03128	COG1120	ATPase activity
C7M28_03129	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M28_03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M28_03131	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M28_03134	COG3866	Pectate lyase
C7M28_03135	COG0471	metal ion transport
C7M28_03136	COG3290	protein histidine kinase activity
C7M28_03137	COG4565	transcriptional regulatory protein
C7M28_03138	COG3181	Tripartite tricarboxylate transporter family receptor
C7M28_03139	COG2851	Citrate transporter
C7M28_03140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M28_03141	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C7M28_03142	COG1254	Belongs to the acylphosphatase family
C7M28_03143	COG2258	MOSC domain
C7M28_03147	COG0024	Methionine aminopeptidase
C7M28_03148	COG1263	PTS System
C7M28_03148	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M28_03149	COG1368	sulfuric ester hydrolase activity
C7M28_03151	COG1115	amino acid carrier protein
C7M28_03152	COG0697	spore germination
C7M28_03153	COG1263	PTS System
C7M28_03153	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M28_03154	COG0366	Alpha amylase catalytic
C7M28_03155	COG2188	Transcriptional regulator
C7M28_03156	COG0778	Nitroreductase
C7M28_03157	COG0737	Belongs to the 5'-nucleotidase family
C7M28_03158	COG0693	protein deglycase activity
C7M28_03159	COG2814	Major facilitator Superfamily
C7M28_03160	COG4840	Belongs to the UPF0435 family
C7M28_03161	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M28_03162	COG4980	gas vesicle protein
C7M28_03163	COG1295	ribonuclease BN
C7M28_03165	COG0477	Major facilitator Superfamily
C7M28_03166	COG0387	Pfam Sodium calcium exchanger
C7M28_03168	COG0668	transmembrane transport
C7M28_03169	COG0535	radical SAM domain protein
C7M28_03171	COG0726	polysaccharide deacetylase
C7M28_03172	COG2084	Dehydrogenase
C7M28_03173	COG0598	Magnesium transport protein CorA
C7M28_03174	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M28_03175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M28_03177	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M28_03178	COG4637	Psort location Cytoplasmic, score
C7M28_03179	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M28_03180	COG0022	dehydrogenase e1 component
C7M28_03181	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M28_03182	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M28_03183	COG3284	Transcriptional regulator
C7M28_03185	COG1742	UPF0060 membrane protein
C7M28_03190	COG4842	Belongs to the WXG100 family
C7M28_03191	COG1486	melibiose metabolic process
C7M28_03192	COG1737	Transcriptional regulator
C7M28_03193	COG1263	PTS System
C7M28_03193	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M28_03194	COG1132	(ABC) transporter
C7M28_03195	COG1132	(ABC) transporter
C7M28_03196	COG2259	Doxx family
C7M28_03197	COG2514	catechol 2,3-dioxygenase activity
C7M28_03198	COG1917	Cupin 2, conserved barrel domain protein
C7M28_03198	COG4977	sequence-specific DNA binding
C7M28_03199	COG2814	Major facilitator Superfamily
C7M28_03200	COG1082	Xylose isomerase domain protein TIM barrel
C7M28_03201	COG0673	inositol 2-dehydrogenase activity
C7M28_03203	COG4585	Histidine kinase
C7M28_03204	COG2197	response regulator
C7M28_03205	COG1131	(ABC) transporter
C7M28_03206	COG1511	domain protein
C7M28_03206	COG0842	Transport permease protein
C7M28_03207	COG0842	Transport permease protein
C7M28_03208	COG1695	Transcriptional regulator
C7M28_03209	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M28_03210	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7M28_03211	COG1309	transcriptional regulator
C7M28_03212	COG2814	Major facilitator Superfamily
C7M28_03213	COG2318	DinB family
C7M28_03214	COG2814	Major facilitator Superfamily
C7M28_03215	COG1846	Transcriptional regulator
C7M28_03216	COG0392	lysyltransferase activity
C7M28_03216	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7M28_03217	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M28_03218	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M28_03219	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M28_03220	COG0384	phenazine biosynthesis protein PhzF
C7M28_03221	COG0778	Nitroreductase
C7M28_03224	COG1090	epimerase
C7M28_03225	COG2137	regulation of response to DNA damage stimulus
C7M28_03228	COG2814	Major facilitator Superfamily
C7M28_03231	COG3103	Sh3 type 3 domain protein
C7M28_03232	COG5658	integral membrane protein
C7M28_03233	COG0596	Alpha beta hydrolase
C7M28_03234	COG0463	Glycosyl transferase, family 2
C7M28_03235	COG4485	Bacterial membrane protein, YfhO
C7M28_03236	COG1988	membrane-bound metal-dependent
C7M28_03237	COG1194	a g-specific adenine glycosylase
C7M28_03239	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_03242	COG3557	Belongs to the UPF0374 family
C7M28_03243	COG1132	(ABC) transporter
C7M28_03244	COG4129	membrane
C7M28_03245	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M28_03246	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7M28_03247	COG0735	belongs to the Fur family
C7M28_03269	COG4326	sporulation control protein
C7M28_03271	COG3340	Belongs to the peptidase S51 family
C7M28_03272	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7M28_03273	COG0277	FAD linked oxidase domain protein
C7M28_03275	COG0753	catalase activity
C7M28_03276	COG1116	anion transmembrane transporter activity
C7M28_03277	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M28_03278	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M28_03279	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M28_03281	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M28_03283	COG1476	TRANSCRIPTIONal
C7M28_03285	COG3382	B3 4 domain protein
C7M28_03286	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7M28_03288	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M28_03289	COG0789	Transcriptional regulator
C7M28_03290	COG1664	Polymer-forming cytoskeletal
C7M28_03291	COG1664	Polymer-forming cytoskeletal
C7M28_03292	COG2766	serine protein kinase
C7M28_03293	COG2718	Belongs to the UPF0229 family
C7M28_03294	COG1846	Transcriptional regulator
C7M28_03295	COG1566	PFAM secretion protein HlyD family protein
C7M28_03296	COG2814	Major facilitator Superfamily
C7M28_03297	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M28_03300	COG1725	Transcriptional regulator
C7M28_03301	COG1131	(ABC) transporter
C7M28_03302	COG1131	(ABC) transporter
C7M28_03303	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M28_03304	COG1278	Cold shock
C7M28_03305	COG1464	Belongs to the NlpA lipoprotein family
C7M28_03306	COG3706	GGDEF domain
C7M28_03307	COG1823	symporter activity
C7M28_03313	COG5577	PFAM Coat F domain
C7M28_03314	COG1525	nuclease
C7M28_03314	COG0737	Belongs to the 5'-nucleotidase family
C7M28_03314	COG4085	toxin activity
C7M28_03315	COG3764	Sortase (surface protein transpeptidase)
C7M28_03316	COG0564	pseudouridine synthase activity
C7M28_03318	COG0517	IMP dehydrogenase activity
C7M28_03319	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M28_03320	COG3153	acetyltransferase
C7M28_03320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M28_03321	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M28_03322	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7M28_03323	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M28_03324	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M28_03325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7M28_03326	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M28_03327	COG2203	Gaf domain
C7M28_03327	COG4585	Histidine kinase
C7M28_03328	COG2197	response regulator
C7M28_03329	COG0431	NADPH-dependent FMN reductase
C7M28_03332	COG1388	LysM domain
C7M28_03332	COG0791	NLP P60 protein
C7M28_03333	COG1959	2 iron, 2 sulfur cluster binding
C7M28_03334	COG0668	transmembrane transport
C7M28_03335	COG2719	SpoVR family
C7M28_03336	COG1785	Belongs to the alkaline phosphatase family
C7M28_03337	COG0791	NLP P60 protein
C7M28_03337	COG1388	LysM domain
C7M28_03338	COG0583	DNA-binding transcription factor activity
C7M28_03339	COG0372	Belongs to the citrate synthase family
C7M28_03340	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_03341	COG0531	amino acid
C7M28_03342	COG0733	neurotransmitter:sodium symporter activity
C7M28_03343	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M28_03344	COG0456	acetyltransferase
C7M28_03347	COG1595	DNA-templated transcription, initiation
C7M28_03348	COG0667	Aldo Keto reductase
C7M28_03349	COG0204	Acyl-transferase
C7M28_03350	COG1253	flavin adenine dinucleotide binding
C7M28_03351	COG0789	Transcriptional regulator
C7M28_03352	COG0436	Aminotransferase
C7M28_03353	COG1253	flavin adenine dinucleotide binding
C7M28_03354	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M28_03355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M28_03356	COG0584	glycerophosphoryl diester phosphodiesterase
C7M28_03358	COG0668	transmembrane transport
C7M28_03359	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M28_03360	COG0726	polysaccharide deacetylase
C7M28_03361	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M28_03362	COG1757	Na H antiporter
C7M28_03363	COG0589	response to stress
C7M28_03364	COG1132	(ABC) transporter
C7M28_03365	COG1132	(ABC) transporter
C7M28_03366	COG0702	epimerase
C7M28_03369	COG0189	ligase activity
C7M28_03370	COG0189	ligase activity
C7M28_03371	COG4399	Belongs to the UPF0754 family
C7M28_03372	COG3679	Belongs to the UPF0342 family
C7M28_03373	COG4335	DNA alkylation repair
C7M28_03374	COG0561	phosphatase activity
C7M28_03375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M28_03376	COG0475	glutathione-regulated potassium exporter activity
C7M28_03377	COG0490	domain, Protein
C7M28_03379	COG1024	Enoyl-CoA hydratase
C7M28_03381	COG4152	abc transporter atp-binding protein
C7M28_03382	COG1668	transmembrane transport
C7M28_03383	COG0420	3'-5' exonuclease activity
C7M28_03384	COG4717	serine-type aminopeptidase activity
C7M28_03385	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7M28_03387	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M28_03390	COG1846	Transcriptional regulator
C7M28_03391	COG4980	gas vesicle protein
C7M28_03393	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M28_03394	COG0537	adenosine 5'-monophosphoramidase activity
C7M28_03395	COG1131	(ABC) transporter
C7M28_03396	COG4473	ABC transporter
C7M28_03398	COG1473	amidohydrolase
C7M28_03399	COG3069	C4-dicarboxylate transmembrane transporter activity
C7M28_03401	COG2329	Antibiotic biosynthesis monooxygenase
C7M28_03402	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M28_03403	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7M28_03406	COG1309	transcriptional regulator
C7M28_03407	COG1511	domain protein
C7M28_03408	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M28_03409	COG4377	Putative membrane peptidase family (DUF2324)
C7M28_03410	COG1363	Peptidase, m42
C7M28_03411	COG4405	Protein conserved in bacteria
C7M28_03412	COG1301	dicarboxylic acid transport
C7M28_03413	COG1234	tRNA 3'-trailer cleavage
C7M28_03414	COG0095	Lipoate-protein ligase
C7M28_03415	COG0702	epimerase
C7M28_03416	COG0318	PFAM AMP-dependent synthetase and ligase
C7M28_03418	COG0501	Belongs to the peptidase M48B family
C7M28_03419	COG1404	Belongs to the peptidase S8 family
C7M28_03420	COG0456	acetyltransferase
C7M28_03421	COG0604	alcohol dehydrogenase
C7M28_03422	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M28_03423	COG0406	alpha-ribazole phosphatase activity
C7M28_03424	COG0183	Belongs to the thiolase family
C7M28_03425	COG0318	PFAM AMP-dependent synthetase and ligase
C7M28_03426	COG1268	BioY protein
C7M28_03427	COG0840	transmembrane signaling receptor activity
C7M28_03428	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M28_03428	COG0723	plastoquinol--plastocyanin reductase activity
C7M28_03429	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_03431	COG4903	ComK protein
C7M28_03432	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_03434	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M28_03437	COG0398	Pfam SNARE associated Golgi protein
C7M28_03438	COG0681	Belongs to the peptidase S26 family
C7M28_03439	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M28_03440	COG1846	Transcriptional regulator
C7M28_03441	COG0738	Major facilitator superfamily
C7M28_03442	COG0673	inositol 2-dehydrogenase activity
C7M28_03443	COG0561	phosphatase activity
C7M28_03444	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M28_03445	COG1609	Transcriptional regulator
C7M28_03446	COG3180	Ammonia monooxygenase
C7M28_03447	COG2814	Major facilitator Superfamily
C7M28_03447	COG0477	Major facilitator Superfamily
C7M28_03448	COG4533	DNA binding
C7M28_03450	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M28_03451	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7M28_03452	COG1074	ATP-dependent DNA helicase activity
C7M28_03453	COG0420	3'-5' exonuclease activity
C7M28_03454	COG0419	ATPase involved in DNA repair
C7M28_03455	COG1403	HNH endonuclease
C7M28_03463	COG5337	Spore coat protein CotH
C7M28_03464	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7M28_03466	COG1404	Belongs to the peptidase S8 family
C7M28_03468	COG0367	asparagine synthase
C7M28_03469	COG2318	DinB family
C7M28_03470	COG1562	ergosterol biosynthetic process
C7M28_03471	COG0534	Mate efflux family protein
C7M28_03472	COG2207	Transcriptional regulator
C7M28_03472	COG1917	Cupin 2, conserved barrel domain protein
C7M28_03473	COG1609	Transcriptional regulator
C7M28_03474	COG0673	inositol 2-dehydrogenase activity
C7M28_03475	COG2318	DinB family
C7M28_03476	COG1279	arginine transmembrane transporter activity
C7M28_03477	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M28_03478	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M28_03479	COG2267	carboxylic ester hydrolase activity
C7M28_03480	COG0529	Catalyzes the synthesis of activated sulfate
C7M28_03481	COG2046	Belongs to the sulfate adenylyltransferase family
C7M28_03482	COG0175	sulfate reduction
C7M28_03483	COG2045	Belongs to the ComB family
C7M28_03484	COG1809	phosphosulfolactate synthase activity
C7M28_03485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M28_03486	COG4948	Mandelate Racemase Muconate Lactonizing
C7M28_03487	COG2814	Major facilitator Superfamily
C7M28_03488	COG0454	-acetyltransferase
C7M28_03489	COG2153	protein acetylation
C7M28_03490	COG0646	methionine synthase
C7M28_03490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M28_03491	COG1666	GTP binding
C7M28_03492	COG2996	Protein conserved in bacteria
C7M28_03496	COG1695	Transcriptional regulator
C7M28_03499	COG3227	Zinc metalloprotease (Elastase)
C7M28_03500	COG1307	EDD domain protein, DegV family
C7M28_03501	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M28_03504	COG0561	phosphatase activity
C7M28_03505	COG1073	alpha beta
C7M28_03506	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M28_03508	COG0277	FAD linked oxidase domain protein
C7M28_03509	COG2271	Major facilitator Superfamily
C7M28_03510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7M28_03511	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7M28_03513	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M28_03514	COG0505	Belongs to the CarA family
C7M28_03515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M28_03516	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M28_03519	COG2267	carboxylic ester hydrolase activity
C7M28_03521	COG1744	ABC transporter substrate-binding protein PnrA-like
C7M28_03524	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M28_03525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M28_03526	COG5504	Zn-dependent protease
C7M28_03527	COG0444	Belongs to the ABC transporter superfamily
C7M28_03528	COG4608	Belongs to the ABC transporter superfamily
C7M28_03530	COG0601	transmembrane transport
C7M28_03531	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M28_03533	COG0180	Tryptophanyl-tRNA synthetase
C7M28_03534	COG4166	transmembrane transport
C7M28_03535	COG0601	transmembrane transport
C7M28_03536	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M28_03537	COG0444	Belongs to the ABC transporter superfamily
C7M28_03538	COG4608	Belongs to the ABC transporter superfamily
C7M28_03539	COG2814	Major facilitator Superfamily
C7M28_03540	COG0456	acetyltransferase
C7M28_03541	COG1393	Belongs to the ArsC family
C7M28_03542	COG0861	Integral membrane protein TerC family
C7M28_03543	COG4862	establishment of competence for transformation
C7M28_03544	COG4469	Competence protein
C7M28_03545	COG1164	Oligoendopeptidase f
C7M28_03549	COG2346	COG2346, Truncated hemoglobins
C7M28_03550	COG0741	lytic transglycosylase activity
C7M28_03551	COG4116	CYTH
C7M28_03553	COG2357	RelA SpoT domain protein
C7M28_03554	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M28_03555	COG0564	pseudouridine synthase activity
C7M28_03556	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7M28_03557	COG0475	glutathione-regulated potassium exporter activity
C7M28_03557	COG0569	domain protein
C7M28_03558	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7M28_03559	COG0352	thiamine-phosphate diphosphorylase activity
C7M28_03560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M28_03561	COG2104	thiamine diphosphate biosynthetic process
C7M28_03562	COG2022	thiamine diphosphate biosynthetic process
C7M28_03563	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M28_03564	COG0351	phosphomethylpyrimidine kinase
C7M28_03565	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M28_03576	COG0210	DNA helicase
C7M28_03578	COG2153	protein acetylation
C7M28_03579	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M28_03580	COG2382	esterase
C7M28_03581	COG0626	cystathionine gamma-synthase activity
C7M28_03582	COG0626	cystathionine gamma-synthase activity
C7M28_03583	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M28_03584	COG5505	Protein of unknown function (DUF819)
C7M28_03591	COG3677	Transposase
C7M28_03594	COG5484	DNA packaging
C7M28_03595	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M28_03596	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_03598	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M28_03598	COG3711	transcriptional antiterminator
C7M28_03599	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M28_03599	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M28_03599	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M28_03600	COG1482	cell wall glycoprotein biosynthetic process
C7M28_03602	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M28_03604	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M28_03607	COG0109	protoheme IX farnesyltransferase activity
C7M28_03609	COG0726	polysaccharide deacetylase
C7M28_03612	COG5504	Zn-dependent protease
C7M28_03613	COG2205	protein histidine kinase activity
C7M28_03615	COG3383	formate dehydrogenase (NAD+) activity
C7M28_03616	COG2427	Protein of unknown function (DUF1641)
C7M28_03618	COG1051	belongs to the nudix hydrolase family
C7M28_03620	COG2124	cytochrome p450
C7M28_03621	COG1819	glycosyl
C7M28_03623	COG1587	Uroporphyrinogen-III synthase
C7M28_03624	COG0390	transport system, permease component
C7M28_03625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M28_03626	COG0697	spore germination
C7M28_03627	COG4297	protein containing double-stranded beta helix domain
C7M28_03629	COG1252	NADH dehydrogenase
C7M28_03630	COG1904	glucuronate isomerase
C7M28_03631	COG2211	Major facilitator Superfamily
C7M28_03632	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M28_03633	COG1063	alcohol dehydrogenase
C7M28_03634	COG1312	Catalyzes the dehydration of D-mannonate
C7M28_03635	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_03636	COG2271	Major facilitator Superfamily
C7M28_03637	COG1609	Transcriptional regulator
C7M28_03638	COG0246	Mannitol dehydrogenase
C7M28_03639	COG2721	sulfolactate sulfo-lyase activity
C7M28_03640	COG0730	response to heat
C7M28_03641	COG2318	DinB family
C7M28_03642	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M28_03643	COG0457	Tetratricopeptide repeat
C7M28_03645	COG2350	Protein conserved in bacteria
C7M28_03646	COG1388	LysM domain
C7M28_03646	COG3409	Peptidoglycan-binding domain 1 protein
C7M28_03646	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M28_03648	COG4195	phage-related replication protein
C7M28_03649	COG3546	catalase activity
C7M28_03650	COG2856	Zn peptidase
C7M28_03651	COG1396	sequence-specific DNA binding
C7M28_03653	COG1522	sequence-specific DNA binding
C7M28_03654	COG1484	DNA-dependent DNA replication
C7M28_03658	COG1595	DNA-templated transcription, initiation
C7M28_03659	COG3728	DNA packaging
C7M28_03659	COG5484	DNA packaging
C7M28_03660	COG1783	phage Terminase large subunit
C7M28_03661	COG5518	Phage portal protein
C7M28_03662	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M28_03663	COG4653	Phage capsid family
C7M28_03671	COG5412	phage tail tape measure protein
C7M28_03671	COG3953	SLT domain
C7M28_03672	COG1652	LysM domain
C7M28_03673	COG4193	domain, Protein
C7M28_03675	COG3628	GPW Gp25 family protein
C7M28_03676	COG3299	homolog of phage Mu protein gp47
C7M28_03677	COG3778	Protein conserved in bacteria
C7M28_03685	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M28_03685	COG3409	Peptidoglycan-binding domain 1 protein
C7M28_03688	COG0306	phosphate transporter
C7M28_03689	COG1392	Phosphate transport regulator
C7M28_03690	COG0531	amino acid
C7M28_03691	COG0346	lactoylglutathione lyase activity
C7M28_03692	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M28_03693	COG0463	Glycosyl transferase, family 2
C7M28_03695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M28_03696	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M28_03697	COG2362	D-Aminopeptidase
C7M28_03698	COG0601	transmembrane transport
C7M28_03699	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M28_03700	COG0444	Belongs to the ABC transporter superfamily
C7M28_03701	COG4166	transmembrane transport
C7M28_03703	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M28_03704	COG4948	Mandelate Racemase Muconate Lactonizing
C7M28_03705	COG0791	NLP P60 protein
C7M28_03706	COG4608	Belongs to the ABC transporter superfamily
C7M28_03707	COG2706	6-phosphogluconolactonase activity
C7M28_03708	COG1834	amidinotransferase
C7M28_03709	COG1607	acyl-coa hydrolase
C7M28_03710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M28_03710	COG1017	nitric oxide dioxygenase activity
C7M28_03712	COG2323	membrane
C7M28_03713	COG2318	DinB family
C7M28_03714	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M28_03715	COG2076	Multidrug Resistance protein
C7M28_03716	COG2076	Multidrug Resistance protein
C7M28_03717	COG0788	formyltetrahydrofolate deformylase activity
C7M28_03718	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M28_03719	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M28_03720	COG1764	response to oxidative stress
C7M28_03721	COG1846	Transcriptional regulator
C7M28_03722	COG1764	response to oxidative stress
C7M28_03723	COG0590	tRNA wobble adenosine to inosine editing
C7M28_03724	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M28_03725	COG1404	Belongs to the peptidase S8 family
C7M28_03726	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M28_03727	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M28_03728	COG1122	ATPase activity
C7M28_03729	COG4721	ABC-type cobalt transport system, permease component
C7M28_03731	COG0745	RESPONSE REGULATOR receiver
C7M28_03732	COG5002	protein histidine kinase activity
C7M28_03732	COG3850	Histidine kinase
C7M28_03733	COG3212	peptidase
C7M28_03734	COG3212	peptidase
C7M28_03737	COG2239	Acts as a magnesium transporter
C7M28_03738	COG0789	Transcriptional regulator
C7M28_03741	COG1846	Transcriptional regulator
C7M28_03742	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M28_03743	COG0726	polysaccharide deacetylase
C7M28_03744	COG1408	metallophosphoesterase
C7M28_03746	COG0463	Glycosyl transferase, family 2
C7M28_03747	COG1793	dna ligase
C7M28_03747	COG3285	dna ligase
C7M28_03748	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C7M28_03749	COG5001	Diguanylate cyclase
C7M28_03749	COG3300	MHYT domain
C7M28_03750	COG0586	Pfam SNARE associated Golgi protein
C7M28_03751	COG0861	Integral membrane protein TerC family
C7M28_03752	COG1191	sigma factor activity
C7M28_03756	COG0501	Belongs to the peptidase M48B family
C7M28_03757	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M28_03760	COG3594	Acyltransferase
C7M28_03761	COG5002	protein histidine kinase activity
C7M28_03762	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M28_03764	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C7M28_03765	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
C7M28_03766	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M28_03767	COG0436	Aminotransferase
C7M28_03768	COG1850	ribulose-bisphosphate carboxylase activity
C7M28_03769	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
C7M28_03770	COG0235	Class ii aldolase
C7M28_03771	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C7M28_03772	COG3339	Conserved Protein
C7M28_03775	COG3852	Histidine kinase
C7M28_03776	COG1846	Transcriptional regulator
C7M28_03777	COG1360	Flagellar Motor Protein
C7M28_03778	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M28_03779	COG0542	response to heat
C7M28_03780	COG3949	Membrane
C7M28_03781	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7M28_03782	COG0720	synthase
C7M28_03783	COG0602	queuosine metabolic process
C7M28_03784	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7M28_03785	COG1733	regulation of RNA biosynthetic process
C7M28_03786	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_03787	COG4641	Protein conserved in bacteria
C7M28_03787	COG1388	LysM domain
C7M28_03788	COG1388	LysM domain
C7M28_03789	COG3858	chitin binding
C7M28_03791	COG4873	Protein conserved in bacteria
C7M28_03793	COG3773	Cell wall hydrolase
C7M28_03794	COG2244	polysaccharide biosynthetic process
C7M28_03795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M28_03796	COG2217	Heavy metal translocating P-type atpase
C7M28_03798	COG0006	proline dipeptidase activity
C7M28_03799	COG1609	Transcriptional regulator
C7M28_03801	COG3711	transcriptional antiterminator
C7M28_03802	COG1263	PTS System
C7M28_03802	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M28_03802	COG2190	(PTS) system
C7M28_03803	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M28_03804	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M28_03806	COG1533	DNA photolyase activity
C7M28_03807	COG0456	acetyltransferase
C7M28_03808	COG0840	transmembrane signaling receptor activity
C7M28_03809	COG2084	Dehydrogenase
C7M28_03810	COG2340	Cysteine-rich secretory protein family
C7M28_03811	COG0768	penicillin binding
C7M28_03812	COG4191	Histidine kinase
C7M28_03813	COG0436	Aminotransferase
C7M28_03815	COG0835	chemotaxis
C7M28_03815	COG0784	Response regulator, receiver
C7M28_03817	COG2814	Major facilitator Superfamily
C7M28_03818	COG1376	ErfK ybiS ycfS ynhG family protein
C7M28_03819	COG1408	metallophosphoesterase
C7M28_03820	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_03821	COG2200	EAL domain
C7M28_03822	COG4703	Protein of unknown function (DUF1797)
C7M28_03823	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C7M28_03825	COG0517	IMP dehydrogenase activity
C7M28_03826	COG0583	DNA-binding transcription factor activity
C7M28_03827	COG0716	FMN binding
C7M28_03829	COG0716	FMN binding
C7M28_03830	COG2171	N-acyltransferase activity
C7M28_03831	COG1473	amidohydrolase
C7M28_03833	COG0668	transmembrane transport
C7M28_03834	COG0450	alkyl hydroperoxide reductase
C7M28_03835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M28_03838	COG0746	molybdenum cofactor guanylyltransferase activity
C7M28_03839	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M28_03840	COG0303	'Molybdopterin
C7M28_03841	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M28_03842	COG0314	molybdopterin synthase activity
C7M28_03843	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7M28_03844	COG1132	(ABC) transporter
C7M28_03845	COG1132	(ABC) transporter
C7M28_03847	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M28_03848	COG1136	(ABC) transporter
C7M28_03849	COG0577	efflux transmembrane transporter activity
C7M28_03850	COG1349	DNA-binding transcription factor activity
C7M28_03851	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M28_03852	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M28_03852	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M28_03852	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M28_03853	COG0681	Belongs to the peptidase S26 family
C7M28_03855	COG0488	(ABC) transporter
C7M28_03856	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M28_03857	COG2309	aminopeptidase activity
C7M28_03859	COG1077	Cell shape determining protein MreB Mrl
C7M28_03860	COG2002	toxin-antitoxin pair type II binding
C7M28_03861	COG3852	Histidine kinase
C7M28_03862	COG2105	PFAM AIG2 family protein
C7M28_03862	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C7M28_03863	COG0569	domain protein
C7M28_03864	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M28_03865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M28_03867	COG0561	phosphatase activity
C7M28_03868	COG0242	peptide deformylase activity
C7M28_03870	COG0497	DNA recombination
C7M28_03871	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M28_03872	COG0022	dehydrogenase e1 component
C7M28_03873	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M28_03874	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M28_03875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M28_03876	COG1982	Orn Lys Arg decarboxylase major
C7M28_03877	COG4476	Belongs to the UPF0223 family
C7M28_03878	COG4493	Belongs to the UPF0637 family
C7M28_03880	COG0483	inositol monophosphate 1-phosphatase activity
C7M28_03882	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7M28_03886	COG1595	DNA-templated transcription, initiation
C7M28_03892	COG4896	Protein conserved in bacteria
C7M28_03894	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7M28_03895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M28_03896	COG2066	Belongs to the glutaminase family
C7M28_03897	COG4838	Belongs to the UPF0358 family
C7M28_03898	COG0772	Belongs to the SEDS family
C7M28_03899	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M28_03900	COG1612	heme a metabolic process
C7M28_03901	COG0109	protoheme IX farnesyltransferase activity
C7M28_03902	COG2010	Cytochrome c
C7M28_03902	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M28_03903	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M28_03904	COG1845	cytochrome c oxidase, subunit III
C7M28_03905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M28_03906	COG3336	cytochrome c oxidase
C7M28_03908	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C7M28_03909	COG2340	Cysteine-rich secretory protein family
C7M28_03912	COG3679	Belongs to the UPF0342 family
C7M28_03913	COG4471	UPF0298 protein
C7M28_03914	COG0742	ribosomal rna small subunit methyltransferase
C7M28_03915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7M28_03916	COG3314	Sporulation integral membrane protein YlbJ
C7M28_03917	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M28_03918	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M28_03919	COG1323	Belongs to the UPF0348 family
C7M28_03921	COG1399	metal-binding, possibly nucleic acid-binding protein
C7M28_03924	COG0454	-acetyltransferase
C7M28_03925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M28_03926	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C7M28_03927	COG2001	Belongs to the MraZ family
C7M28_03928	COG0275	rRNA processing
C7M28_03929	COG4839	cell division protein FtsL
C7M28_03931	COG0768	penicillin binding
C7M28_03932	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7M28_03933	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M28_03934	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M28_03935	COG0772	Belongs to the SEDS family
C7M28_03936	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M28_03937	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7M28_03938	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M28_03939	COG3879	Bacterial protein of unknown function (DUF881)
C7M28_03940	COG3879	Bacterial protein of unknown function (DUF881)
C7M28_03941	COG3856	small basic protein
C7M28_03942	COG0849	cell division
C7M28_03943	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M28_03944	COG4412	M6 family metalloprotease domain protein
C7M28_03944	COG1404	Belongs to the peptidase S8 family
C7M28_03946	COG1191	sigma factor activity
C7M28_03947	COG1191	sigma factor activity
C7M28_03948	COG1119	ATPase activity
C7M28_03949	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M28_03950	COG1873	PFAM PRC-barrel domain
C7M28_03952	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7M28_03953	COG1799	cell septum assembly
C7M28_03954	COG0762	integral membrane protein
C7M28_03955	COG2302	S4 RNA-binding domain
C7M28_03956	COG3599	regulation of cell shape
C7M28_03957	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M28_03958	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M28_03959	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7M28_03960	COG0564	pseudouridine synthase activity
C7M28_03961	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M28_03962	COG2233	PERMEase
C7M28_03963	COG0540	Belongs to the ATCase OTCase family
C7M28_03964	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M28_03965	COG0505	Belongs to the CarA family
C7M28_03966	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M28_03967	COG0543	2 iron, 2 sulfur cluster binding
C7M28_03968	COG0167	dihydroorotate dehydrogenase activity
C7M28_03969	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M28_03970	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M28_03972	COG0175	sulfate reduction
C7M28_03973	COG0306	phosphate transporter
C7M28_03974	COG2046	Belongs to the sulfate adenylyltransferase family
C7M28_03975	COG0529	Catalyzes the synthesis of activated sulfate
C7M28_03976	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M28_03977	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7M28_03978	COG1648	precorrin-2 dehydrogenase activity
C7M28_03979	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C7M28_03980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M28_03981	COG1561	YicC-like family, N-terminal region
C7M28_03983	COG0194	GDP metabolic process
C7M28_03984	COG1758	RNA polymerase activity
C7M28_03985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M28_03986	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M28_03987	COG0242	peptide deformylase activity
C7M28_03988	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7M28_03989	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M28_03989	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M28_03990	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7M28_03991	COG0631	protein serine/threonine phosphatase activity
C7M28_03992	COG2815	serine threonine protein kinase
C7M28_03992	COG0515	serine threonine protein kinase
C7M28_03993	COG1162	GTPase activity
C7M28_03994	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M28_03995	COG1564	THIamine pyrophosphokinase
C7M28_03996	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7M28_03997	COG1302	Protein conserved in bacteria
C7M28_03998	COG1461	Dihydroxyacetone kinase
C7M28_03999	COG1760	l-serine dehydratase
C7M28_04000	COG1760	l-serine dehydratase
C7M28_04001	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M28_04002	COG1349	DNA-binding transcription factor activity
C7M28_04002	COG2050	protein possibly involved in aromatic compounds catabolism
C7M28_04003	COG0416	fatty acid biosynthetic process
C7M28_04004	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M28_04005	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_04007	COG0571	ribonuclease III activity
C7M28_04008	COG1196	nuclear chromosome segregation
C7M28_04009	COG0552	protein localization to endoplasmic reticulum
C7M28_04011	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7M28_04012	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M28_04013	COG0228	four-way junction DNA binding
C7M28_04014	COG1837	Belongs to the UPF0109 family
C7M28_04016	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7M28_04017	COG0336	Belongs to the RNA methyltransferase TrmD family
C7M28_04018	COG0335	large ribosomal subunit rRNA binding
C7M28_04019	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M28_04020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M28_04022	COG2257	FlhB HrpN YscU SpaS Family
C7M28_04023	COG0045	succinate-CoA ligase (ADP-forming) activity
C7M28_04024	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M28_04025	COG0758	DNA mediated transformation
C7M28_04026	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M28_04027	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7M28_04028	COG4974	Belongs to the 'phage' integrase family
C7M28_04029	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7M28_04030	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7M28_04031	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M28_04032	COG1815	bacterial-type flagellum-dependent cell motility
C7M28_04033	COG1558	bacterial-type flagellum-dependent cell motility
C7M28_04034	COG1677	Flagellar hook-basal body complex protein FliE
C7M28_04035	COG1766	The M ring may be actively involved in energy transduction
C7M28_04036	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M28_04037	COG1317	bacterial-type flagellum organization
C7M28_04038	COG1157	protein secretion by the type III secretion system
C7M28_04039	COG2882	bacterial-type flagellum organization
C7M28_04040	COG3334	PFAM MgtE intracellular
C7M28_04041	COG3144	bacterial-type flagellum assembly
C7M28_04042	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7M28_04043	COG4786	Flagellar basal body rod
C7M28_04044	COG1580	Controls the rotational direction of flagella during chemotaxis
C7M28_04045	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M28_04046	COG1776	CheC inhibitor of MCP methylation
C7M28_04046	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M28_04047	COG2201	protein-glutamate methylesterase activity
C7M28_04048	COG3190	flagellar
C7M28_04049	COG1338	Plays a role in the flagellum-specific transport system
C7M28_04050	COG1987	bacterial-type flagellum assembly
C7M28_04051	COG1684	flagellar biosynthetic protein fliR
C7M28_04052	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M28_04053	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M28_04054	COG1419	protein localization to endoplasmic reticulum
C7M28_04055	COG0455	bacterial-type flagellum organization
C7M28_04056	COG2201	protein-glutamate methylesterase activity
C7M28_04057	COG2198	Histidine kinase
C7M28_04057	COG0643	Histidine kinase
C7M28_04058	COG0835	chemotaxis
C7M28_04059	COG1776	CheC inhibitor of MCP methylation
C7M28_04060	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C7M28_04061	COG1191	sigma factor activity
C7M28_04063	COG0052	Belongs to the universal ribosomal protein uS2 family
C7M28_04064	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7M28_04065	COG0528	UMP kinase activity
C7M28_04066	COG0233	cytoplasmic translational termination
C7M28_04067	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M28_04068	COG4589	Belongs to the CDS family
C7M28_04069	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7M28_04070	COG0750	zinc metalloprotease
C7M28_04071	COG0442	prolyl-tRNA aminoacylation
C7M28_04072	COG2176	DNA-directed DNA polymerase activity
C7M28_04073	COG0779	Required for maturation of 30S ribosomal subunits
C7M28_04074	COG0195	Participates in both transcription termination and antitermination
C7M28_04075	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M28_04076	COG1358	cellular component organization or biogenesis
C7M28_04077	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7M28_04078	COG1550	Protein conserved in bacteria
C7M28_04079	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7M28_04080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7M28_04081	COG0196	riboflavin kinase activity
C7M28_04082	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7M28_04083	COG1185	polyribonucleotide nucleotidyltransferase activity
C7M28_04084	COG0726	polysaccharide deacetylase
C7M28_04085	COG0612	Peptidase, M16
C7M28_04086	COG1873	PFAM PRC-barrel domain
C7M28_04087	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M28_04088	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M28_04089	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M28_04090	COG0527	aspartate kinase activity
C7M28_04091	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M28_04092	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M28_04093	COG0740	serine-type endopeptidase activity
C7M28_04095	COG4980	gas vesicle protein
C7M28_04095	COG1674	ftsk spoiiie
C7M28_04096	COG2188	Transcriptional regulator
C7M28_04097	COG2814	Major facilitator Superfamily
C7M28_04098	COG0612	Peptidase, M16
C7M28_04099	COG0612	Peptidase, M16
C7M28_04100	COG0300	oxidoreductase activity
C7M28_04103	COG1426	Protein conserved in bacteria
C7M28_04104	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M28_04105	COG1058	Belongs to the CinA family
C7M28_04105	COG1546	Belongs to the CinA family
C7M28_04106	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7M28_04107	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M28_04108	COG1418	mRNA catabolic process
C7M28_04109	COG1692	metallophosphoesterase
C7M28_04110	COG2359	stage V sporulation protein S
C7M28_04111	COG1063	alcohol dehydrogenase
C7M28_04112	COG0156	8-amino-7-oxononanoate synthase activity
C7M28_04113	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M28_04114	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7M28_04116	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M28_04117	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7M28_04121	COG3226	Transcriptional regulator
C7M28_04122	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M28_04123	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M28_04124	COG3321	synthase
C7M28_04125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M28_04125	COG2070	2-Nitropropane dioxygenase
C7M28_04126	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M28_04127	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M28_04128	COG3425	synthase
C7M28_04129	COG1024	Enoyl-CoA hydratase
C7M28_04130	COG1024	Enoyl-CoA hydratase
C7M28_04131	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_04131	COG3321	synthase
C7M28_04131	COG0300	oxidoreductase activity
C7M28_04131	COG0318	PFAM AMP-dependent synthetase and ligase
C7M28_04131	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_04132	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M28_04132	COG3321	synthase
C7M28_04132	COG4221	oxidoreductase activity
C7M28_04132	COG0300	oxidoreductase activity
C7M28_04133	COG3321	synthase
C7M28_04133	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_04133	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_04133	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M28_04133	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M28_04134	COG1028	Short-chain dehydrogenase reductase Sdr
C7M28_04134	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M28_04134	COG3321	synthase
C7M28_04134	COG4221	oxidoreductase activity
C7M28_04135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7M28_04135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M28_04135	COG3321	synthase
C7M28_04135	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M28_04136	COG2124	cytochrome p450
C7M28_04138	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M28_04139	COG1404	Belongs to the peptidase S8 family
C7M28_04158	COG5280	Phage tail tape measure protein TP901
C7M28_04158	COG3953	SLT domain
C7M28_04169	COG5444	nuclease activity
C7M28_04180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M28_04181	COG0187	DNA topoisomerase II activity
C7M28_04191	COG0194	GDP metabolic process
C7M28_04195	COG0587	DNA-directed DNA polymerase activity
C7M28_04199	COG0328	RNA-DNA hybrid ribonuclease activity
C7M28_04206	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M28_04214	COG0716	FMN binding
C7M28_04215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M28_04216	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M28_04217	COG2887	Belongs to the helicase family. UvrD subfamily
C7M28_04231	COG0582	viral genome integration into host DNA
C7M28_04234	COG1388	LysM domain
C7M28_04234	COG3584	3D domain protein
C7M28_04239	COG0457	Tetratricopeptide repeat