locus-tag	class	description
C7M29_00002	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M29_00003	COG2814	Major facilitator Superfamily
C7M29_00004	COG2814	Major facilitator Superfamily
C7M29_00005	COG1566	PFAM secretion protein HlyD family protein
C7M29_00006	COG1846	Transcriptional regulator
C7M29_00007	COG2718	Belongs to the UPF0229 family
C7M29_00008	COG2766	serine protein kinase
C7M29_00009	COG1664	Polymer-forming cytoskeletal
C7M29_00010	COG1664	Polymer-forming cytoskeletal
C7M29_00011	COG0789	Transcriptional regulator
C7M29_00012	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M29_00014	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7M29_00015	COG3382	B3 4 domain protein
C7M29_00017	COG1476	TRANSCRIPTIONal
C7M29_00019	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M29_00021	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M29_00022	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M29_00023	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M29_00024	COG1116	anion transmembrane transporter activity
C7M29_00025	COG0753	catalase activity
C7M29_00027	COG0277	FAD linked oxidase domain protein
C7M29_00028	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7M29_00029	COG3340	Belongs to the peptidase S51 family
C7M29_00031	COG4326	sporulation control protein
C7M29_00053	COG0735	belongs to the Fur family
C7M29_00054	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7M29_00055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M29_00056	COG4129	membrane
C7M29_00057	COG1132	(ABC) transporter
C7M29_00058	COG3557	Belongs to the UPF0374 family
C7M29_00061	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_00063	COG1194	a g-specific adenine glycosylase
C7M29_00064	COG1988	membrane-bound metal-dependent
C7M29_00065	COG4485	Bacterial membrane protein, YfhO
C7M29_00066	COG0463	Glycosyl transferase, family 2
C7M29_00067	COG0596	Alpha beta hydrolase
C7M29_00068	COG5658	integral membrane protein
C7M29_00069	COG3103	Sh3 type 3 domain protein
C7M29_00072	COG2814	Major facilitator Superfamily
C7M29_00074	COG2137	regulation of response to DNA damage stimulus
C7M29_00075	COG1090	epimerase
C7M29_00078	COG0778	Nitroreductase
C7M29_00079	COG0384	phenazine biosynthesis protein PhzF
C7M29_00080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M29_00081	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M29_00082	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M29_00083	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7M29_00083	COG0392	lysyltransferase activity
C7M29_00084	COG1846	Transcriptional regulator
C7M29_00085	COG2814	Major facilitator Superfamily
C7M29_00086	COG2318	DinB family
C7M29_00087	COG2814	Major facilitator Superfamily
C7M29_00088	COG1309	transcriptional regulator
C7M29_00089	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7M29_00090	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M29_00091	COG1695	Transcriptional regulator
C7M29_00092	COG0842	Transport permease protein
C7M29_00093	COG1511	domain protein
C7M29_00093	COG0842	Transport permease protein
C7M29_00094	COG1131	(ABC) transporter
C7M29_00095	COG2197	response regulator
C7M29_00096	COG4585	Histidine kinase
C7M29_00098	COG2514	catechol 2,3-dioxygenase activity
C7M29_00099	COG2259	Doxx family
C7M29_00100	COG1132	(ABC) transporter
C7M29_00101	COG1132	(ABC) transporter
C7M29_00102	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_00102	COG1263	PTS System
C7M29_00103	COG1737	Transcriptional regulator
C7M29_00104	COG1486	melibiose metabolic process
C7M29_00105	COG4842	Belongs to the WXG100 family
C7M29_00110	COG1742	UPF0060 membrane protein
C7M29_00112	COG3284	Transcriptional regulator
C7M29_00113	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M29_00114	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M29_00115	COG0022	dehydrogenase e1 component
C7M29_00116	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M29_00118	COG4637	Psort location Cytoplasmic, score
C7M29_00119	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M29_00121	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M29_00122	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M29_00123	COG0598	Magnesium transport protein CorA
C7M29_00124	COG2084	Dehydrogenase
C7M29_00125	COG0726	polysaccharide deacetylase
C7M29_00127	COG0535	radical SAM domain protein
C7M29_00128	COG0668	transmembrane transport
C7M29_00130	COG0387	Pfam Sodium calcium exchanger
C7M29_00131	COG0477	Major facilitator Superfamily
C7M29_00133	COG1295	ribonuclease BN
C7M29_00134	COG4980	gas vesicle protein
C7M29_00135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M29_00136	COG4840	Belongs to the UPF0435 family
C7M29_00137	COG2814	Major facilitator Superfamily
C7M29_00138	COG0693	protein deglycase activity
C7M29_00139	COG0737	Belongs to the 5'-nucleotidase family
C7M29_00140	COG0778	Nitroreductase
C7M29_00141	COG2188	Transcriptional regulator
C7M29_00142	COG0366	Alpha amylase catalytic
C7M29_00143	COG1263	PTS System
C7M29_00143	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_00144	COG0697	spore germination
C7M29_00147	COG0531	amino acid
C7M29_00148	COG1115	amino acid carrier protein
C7M29_00150	COG1368	sulfuric ester hydrolase activity
C7M29_00151	COG1263	PTS System
C7M29_00151	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_00152	COG0024	Methionine aminopeptidase
C7M29_00156	COG2258	MOSC domain
C7M29_00157	COG1254	Belongs to the acylphosphatase family
C7M29_00158	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C7M29_00159	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M29_00160	COG2851	Citrate transporter
C7M29_00161	COG3181	Tripartite tricarboxylate transporter family receptor
C7M29_00162	COG4565	transcriptional regulatory protein
C7M29_00163	COG3290	protein histidine kinase activity
C7M29_00164	COG0471	metal ion transport
C7M29_00165	COG3866	Pectate lyase
C7M29_00168	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M29_00169	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M29_00170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M29_00171	COG1120	ATPase activity
C7M29_00172	COG2130	NADP-dependent
C7M29_00173	COG0456	acetyltransferase
C7M29_00174	COG0513	Belongs to the DEAD box helicase family
C7M29_00175	COG0488	(ABC) transporter
C7M29_00176	COG2814	Major facilitator Superfamily
C7M29_00177	COG0789	Transcriptional regulator
C7M29_00179	COG0488	(ABC) transporter
C7M29_00180	COG0840	transmembrane signaling receptor activity
C7M29_00181	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_00182	COG0531	amino acid
C7M29_00183	COG1011	Hydrolase
C7M29_00184	COG2223	nitrite transmembrane transporter activity
C7M29_00185	COG1442	glycosyl transferase family 8
C7M29_00186	COG1216	Glycosyl transferase, family 2
C7M29_00187	COG1442	glycosyl transferase family 8
C7M29_00188	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M29_00189	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7M29_00190	COG1368	sulfuric ester hydrolase activity
C7M29_00191	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M29_00191	COG2124	cytochrome p450
C7M29_00193	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M29_00194	COG0670	Belongs to the BI1 family
C7M29_00195	COG5583	Uncharacterized small protein (DUF2292)
C7M29_00198	COG0346	lactoylglutathione lyase activity
C7M29_00199	COG2329	Antibiotic biosynthesis monooxygenase
C7M29_00200	COG2323	membrane
C7M29_00201	COG1486	melibiose metabolic process
C7M29_00202	COG0395	ABC-type sugar transport system, permease component
C7M29_00203	COG4209	transmembrane transport
C7M29_00204	COG1653	transport
C7M29_00206	COG1874	Beta-galactosidase
C7M29_00207	COG2755	lipolytic protein G-D-S-L family
C7M29_00208	COG3401	FG-GAP repeat protein
C7M29_00209	COG3401	FG-GAP repeat protein
C7M29_00210	COG5578	integral membrane protein
C7M29_00212	COG2755	lipolytic protein G-D-S-L family
C7M29_00213	COG2207	Transcriptional regulator
C7M29_00214	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M29_00215	COG0395	ABC-type sugar transport system, permease component
C7M29_00216	COG1175	transmembrane transport
C7M29_00217	COG1653	transport
C7M29_00218	COG4753	response regulator
C7M29_00218	COG2207	Transcriptional regulator
C7M29_00219	COG2972	Histidine kinase
C7M29_00220	COG5578	integral membrane protein
C7M29_00221	COG0454	-acetyltransferase
C7M29_00222	COG3546	catalase activity
C7M29_00225	COG0702	epimerase
C7M29_00226	COG3631	Ketosteroid isomerase-related protein
C7M29_00227	COG1309	transcriptional regulator
C7M29_00229	COG0217	transcriptional regulatory protein
C7M29_00231	COG0457	Tetratricopeptide repeat
C7M29_00234	COG3391	amine dehydrogenase activity
C7M29_00236	COG5444	nuclease activity
C7M29_00243	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C7M29_00244	COG0732	type I restriction modification DNA specificity domain
C7M29_00247	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M29_00248	COG1597	lipid kinase activity
C7M29_00249	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7M29_00250	COG1309	transcriptional regulator
C7M29_00251	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M29_00252	COG0154	amidase activity
C7M29_00253	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M29_00254	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M29_00255	COG1285	pathogenesis
C7M29_00256	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M29_00257	COG4851	CamS sex pheromone cAM373 precursor
C7M29_00258	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7M29_00259	COG0210	DNA helicase
C7M29_00260	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C7M29_00261	COG0069	glutamate synthase activity
C7M29_00262	COG4496	protein, YerC YecD
C7M29_00263	COG1470	cell adhesion involved in biofilm formation
C7M29_00264	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M29_00266	COG0531	amino acid
C7M29_00267	COG1522	sequence-specific DNA binding
C7M29_00268	COG0151	Belongs to the GarS family
C7M29_00269	COG0138	bifunctional purine biosynthesis protein purh
C7M29_00270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M29_00271	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7M29_00272	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7M29_00273	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M29_00274	COG0047	phosphoribosylformylglycinamidine synthase activity
C7M29_00275	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M29_00276	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M29_00277	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M29_00278	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M29_00279	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7M29_00281	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C7M29_00283	COG3064	Membrane
C7M29_00284	COG2252	PERMEase
C7M29_00285	COG0519	Catalyzes the synthesis of GMP from XMP
C7M29_00285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7M29_00286	COG1305	Transglutaminase-like
C7M29_00287	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C7M29_00288	COG0714	Associated with various cellular activities
C7M29_00289	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M29_00290	COG1113	amino acid transport
C7M29_00291	COG2132	Multicopper oxidase
C7M29_00293	COG2267	carboxylic ester hydrolase activity
C7M29_00295	COG0823	Involved in the tonB-independent uptake of proteins
C7M29_00296	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7M29_00297	COG1063	alcohol dehydrogenase
C7M29_00298	COG2814	Major facilitator Superfamily
C7M29_00300	COG4260	virion core protein, lumpy skin disease virus
C7M29_00301	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7M29_00302	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M29_00303	COG1842	Phage shock protein A
C7M29_00304	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M29_00305	COG2211	Major facilitator Superfamily
C7M29_00306	COG1063	alcohol dehydrogenase
C7M29_00307	COG0457	Tetratricopeptide repeat
C7M29_00308	COG1073	alpha beta
C7M29_00309	COG0459	protein refolding
C7M29_00311	COG1266	CAAX protease self-immunity
C7M29_00313	COG0805	protein transport
C7M29_00314	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M29_00315	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7M29_00316	COG0315	cyclic pyranopterin monophosphate synthase activity
C7M29_00317	COG0488	(ABC) transporter
C7M29_00318	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M29_00319	COG0456	acetyltransferase
C7M29_00320	COG1214	PFAM Peptidase M22, glycoprotease
C7M29_00321	COG0802	atpase or kinase
C7M29_00322	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7M29_00331	COG4124	Belongs to the glycosyl hydrolase 26 family
C7M29_00332	COG1482	cell wall glycoprotein biosynthetic process
C7M29_00333	COG1940	carbohydrate kinase activity
C7M29_00334	COG2188	Transcriptional regulator
C7M29_00335	COG2723	6-phospho-beta-galactosidase activity
C7M29_00336	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M29_00337	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M29_00338	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M29_00339	COG2814	Major facilitator Superfamily
C7M29_00340	COG1388	LysM domain
C7M29_00341	COG1078	dGTPase activity
C7M29_00342	COG0454	-acetyltransferase
C7M29_00344	COG5646	InterPro IPR014922
C7M29_00345	COG1785	Belongs to the alkaline phosphatase family
C7M29_00347	COG1819	glycosyl
C7M29_00348	COG3858	chitin binding
C7M29_00348	COG1388	LysM domain
C7M29_00349	COG1802	Transcriptional regulator
C7M29_00350	COG0730	response to heat
C7M29_00351	COG2814	Major facilitator Superfamily
C7M29_00352	COG1846	Transcriptional regulator
C7M29_00353	COG0778	Nitroreductase
C7M29_00354	COG1033	growth of symbiont in host cell
C7M29_00354	COG2409	Drug exporters of the RND superfamily
C7M29_00355	COG1846	Transcriptional regulator
C7M29_00356	COG2318	DinB family
C7M29_00357	COG1113	amino acid transport
C7M29_00359	COG0456	acetyltransferase
C7M29_00361	COG1309	transcriptional regulator
C7M29_00364	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M29_00365	COG2323	membrane
C7M29_00366	COG2323	membrane
C7M29_00370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M29_00371	COG2259	Doxx family
C7M29_00372	COG0346	lactoylglutathione lyase activity
C7M29_00373	COG0778	Nitroreductase
C7M29_00374	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M29_00375	COG0789	Transcriptional regulator
C7M29_00375	COG4978	Transcriptional regulator
C7M29_00376	COG1811	Na channel or pump
C7M29_00377	COG0596	Alpha beta hydrolase
C7M29_00378	COG2409	Drug exporters of the RND superfamily
C7M29_00379	COG2197	response regulator
C7M29_00380	COG4585	Histidine kinase
C7M29_00382	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M29_00383	COG0640	Transcriptional regulator
C7M29_00384	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M29_00385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M29_00386	COG0697	spore germination
C7M29_00387	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M29_00388	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M29_00389	COG0640	Transcriptional regulator
C7M29_00390	COG1309	transcriptional regulator
C7M29_00391	COG2814	Major facilitator Superfamily
C7M29_00392	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M29_00393	COG1733	regulation of RNA biosynthetic process
C7M29_00394	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M29_00395	COG1733	regulation of RNA biosynthetic process
C7M29_00396	COG3545	Serine hydrolase
C7M29_00397	COG2030	dehydratase
C7M29_00398	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M29_00399	COG0697	spore germination
C7M29_00400	COG1309	transcriptional regulator
C7M29_00404	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C7M29_00406	COG0477	Major facilitator Superfamily
C7M29_00407	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M29_00408	COG2207	Transcriptional regulator
C7M29_00408	COG3708	Transcriptional regulator
C7M29_00409	COG3708	Transcriptional regulator
C7M29_00409	COG2207	Transcriptional regulator
C7M29_00410	COG0697	spore germination
C7M29_00411	COG2207	Transcriptional regulator
C7M29_00411	COG1917	Cupin 2, conserved barrel domain protein
C7M29_00412	COG0697	spore germination
C7M29_00413	COG1329	Transcriptional regulator
C7M29_00414	COG1278	Cold shock
C7M29_00415	COG0693	protein deglycase activity
C7M29_00421	COG5444	nuclease activity
C7M29_00423	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M29_00431	COG3091	SprT-like family
C7M29_00432	COG2183	response to ionizing radiation
C7M29_00433	COG2208	phosphoserine phosphatase activity
C7M29_00434	COG1191	sigma factor activity
C7M29_00435	COG2172	sigma factor antagonist activity
C7M29_00436	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M29_00437	COG2208	phosphoserine phosphatase activity
C7M29_00438	COG2172	sigma factor antagonist activity
C7M29_00439	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M29_00440	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M29_00441	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M29_00442	COG0864	Transcriptional regulator
C7M29_00443	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M29_00444	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7M29_00445	COG0736	holo-[acyl-carrier-protein] synthase activity
C7M29_00446	COG0705	Rhomboid family
C7M29_00447	COG3428	Bacterial PH domain
C7M29_00448	COG3402	PFAM membrane-flanked domain
C7M29_00449	COG0513	Belongs to the DEAD box helicase family
C7M29_00450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M29_00451	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M29_00452	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M29_00453	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M29_00456	COG1960	acyl-CoA dehydrogenase activity
C7M29_00458	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M29_00459	COG1131	(ABC) transporter
C7M29_00461	COG0628	permease
C7M29_00462	COG1301	dicarboxylic acid transport
C7M29_00463	COG4565	transcriptional regulatory protein
C7M29_00464	COG3290	protein histidine kinase activity
C7M29_00465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7M29_00466	COG3546	catalase activity
C7M29_00467	COG2329	Antibiotic biosynthesis monooxygenase
C7M29_00468	COG0662	Cupin 2, conserved barrel domain protein
C7M29_00469	COG3729	General stress protein
C7M29_00470	COG2217	Heavy metal translocating P-type atpase
C7M29_00471	COG4876	unkown
C7M29_00472	COG2261	transglycosylase associated protein
C7M29_00473	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M29_00479	COG0028	Belongs to the TPP enzyme family
C7M29_00480	COG0494	nUDIX hydrolase
C7M29_00481	COG0531	amino acid
C7M29_00483	COG1215	transferase activity, transferring glycosyl groups
C7M29_00484	COG5298	Protein conserved in bacteria
C7M29_00485	COG3706	GGDEF domain
C7M29_00486	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C7M29_00487	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M29_00487	COG0551	DNA topoisomerase type I activity
C7M29_00488	COG1522	sequence-specific DNA binding
C7M29_00489	COG2814	Major facilitator Superfamily
C7M29_00491	COG3871	stress protein (general stress protein 26)
C7M29_00492	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M29_00493	COG1917	Cupin 2, conserved barrel domain protein
C7M29_00494	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_00495	COG2226	methyltransferase
C7M29_00496	COG0318	PFAM AMP-dependent synthetase and ligase
C7M29_00497	COG3711	transcriptional antiterminator
C7M29_00498	COG4989	oxidoreductase activity
C7M29_00499	COG4989	oxidoreductase activity
C7M29_00500	COG0768	penicillin binding
C7M29_00501	COG2329	Antibiotic biosynthesis monooxygenase
C7M29_00503	COG2755	lipolytic protein G-D-S-L family
C7M29_00504	COG1414	Transcriptional regulator
C7M29_00505	COG1984	allophanate hydrolase subunit 2
C7M29_00506	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7M29_00507	COG4336	lyase activity
C7M29_00508	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M29_00509	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C7M29_00510	COG0561	phosphatase activity
C7M29_00512	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M29_00513	COG0412	Dienelactone hydrolase
C7M29_00514	COG0681	Belongs to the peptidase S26 family
C7M29_00515	COG0473	3-isopropylmalate dehydrogenase activity
C7M29_00516	COG0246	Mannitol dehydrogenase
C7M29_00517	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M29_00518	COG2213	PTS system mannitol-specific
C7M29_00520	COG1349	DNA-binding transcription factor activity
C7M29_00521	COG2372	response to copper ion
C7M29_00521	COG1276	copper resistance
C7M29_00522	COG4549	nuclear export factor GLE1
C7M29_00523	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_00524	COG4975	Glucose uptake
C7M29_00525	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_00526	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M29_00527	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M29_00528	COG0640	Transcriptional regulator
C7M29_00529	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M29_00530	COG0778	Nitroreductase
C7M29_00531	COG1309	transcriptional regulator
C7M29_00532	COG2814	Major facilitator Superfamily
C7M29_00533	COG4607	ABC-type enterochelin transport system periplasmic component
C7M29_00534	COG4604	ABC transporter, ATP-binding protein
C7M29_00535	COG4605	iron ion homeostasis
C7M29_00536	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M29_00537	COG0527	aspartate kinase activity
C7M29_00541	COG0457	Tetratricopeptide repeat
C7M29_00542	COG3850	Histidine kinase
C7M29_00542	COG5002	protein histidine kinase activity
C7M29_00543	COG0745	RESPONSE REGULATOR receiver
C7M29_00544	COG0577	efflux transmembrane transporter activity
C7M29_00545	COG1136	(ABC) transporter
C7M29_00546	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M29_00548	COG0697	spore germination
C7M29_00550	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M29_00551	COG3104	oligopeptide transport
C7M29_00552	COG0596	Alpha beta hydrolase
C7M29_00555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M29_00556	COG0163	prenyltransferase activity
C7M29_00557	COG0583	DNA-binding transcription factor activity
C7M29_00558	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M29_00559	COG0765	amino acid transport
C7M29_00560	COG1126	abc transporter atp-binding protein
C7M29_00561	COG2364	Membrane
C7M29_00563	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M29_00564	COG0697	spore germination
C7M29_00566	COG2814	Major facilitator Superfamily
C7M29_00567	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7M29_00568	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_00569	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_00570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_00571	COG1733	regulation of RNA biosynthetic process
C7M29_00572	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7M29_00573	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M29_00574	COG0840	transmembrane signaling receptor activity
C7M29_00574	COG3290	protein histidine kinase activity
C7M29_00575	COG3209	COG3209 Rhs family protein
C7M29_00577	COG2723	6-phospho-beta-galactosidase activity
C7M29_00579	COG1714	RDD family
C7M29_00580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M29_00581	COG0765	amino acid transport
C7M29_00582	COG0523	cobalamin synthesis protein
C7M29_00583	COG1376	ErfK ybiS ycfS ynhG family protein
C7M29_00584	COG1469	GTP cyclohydrolase I activity
C7M29_00585	COG2223	nitrite transmembrane transporter activity
C7M29_00586	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M29_00587	COG0243	molybdopterin cofactor binding
C7M29_00588	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M29_00589	COG2146	nitrite reductase [NAD(P)H] activity
C7M29_00590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M29_00590	COG1587	Uroporphyrinogen-III synthase
C7M29_00591	COG0492	ferredoxin-NADP+ reductase activity
C7M29_00592	COG2267	carboxylic ester hydrolase activity
C7M29_00593	COG0701	Predicted permease
C7M29_00594	COG3689	TIGRFAM TIGR03943 family protein
C7M29_00595	COG2508	Transcriptional regulator
C7M29_00596	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M29_00597	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_00598	COG0506	proline dehydrogenase activity
C7M29_00599	COG3541	Predicted nucleotidyltransferase
C7M29_00600	COG3458	cephalosporin-C deacetylase activity
C7M29_00601	COG0583	DNA-binding transcription factor activity
C7M29_00602	COG2226	methyltransferase
C7M29_00603	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M29_00604	COG1660	Displays ATPase and GTPase activities
C7M29_00605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7M29_00606	COG3665	Urea carboxylase-associated protein
C7M29_00607	COG1113	amino acid transport
C7M29_00608	COG3403	YqcI/YcgG family
C7M29_00609	COG1280	lysine exporter protein (LysE YggA)
C7M29_00610	COG1846	Transcriptional regulator
C7M29_00611	COG2814	Major facilitator Superfamily
C7M29_00612	COG1620	l-lactate permease
C7M29_00613	COG0039	L-malate dehydrogenase activity
C7M29_00614	COG0366	Alpha amylase catalytic
C7M29_00616	COG1288	antiporter activity
C7M29_00617	COG1473	amidohydrolase
C7M29_00618	COG2113	Glycine betaine
C7M29_00619	COG4176	ABC-type proline glycine betaine transport system permease component
C7M29_00620	COG4175	Glycine betaine
C7M29_00620	COG0517	IMP dehydrogenase activity
C7M29_00621	COG0640	Transcriptional regulator
C7M29_00622	COG2814	Major facilitator Superfamily
C7M29_00623	COG0477	Major facilitator Superfamily
C7M29_00624	COG3853	Toxic anion resistance protein (TelA)
C7M29_00626	COG0861	Integral membrane protein TerC family
C7M29_00627	COG2310	stress, protein
C7M29_00628	COG2310	stress, protein
C7M29_00629	COG2310	stress, protein
C7M29_00630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M29_00631	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M29_00632	COG1121	(ABC) transporter
C7M29_00633	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M29_00634	COG0366	Alpha amylase catalytic
C7M29_00635	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_00636	COG0457	Tetratricopeptide repeat
C7M29_00637	COG1876	peptidase activity
C7M29_00638	COG1595	DNA-templated transcription, initiation
C7M29_00639	COG1595	DNA-templated transcription, initiation
C7M29_00641	COG0667	Aldo Keto reductase
C7M29_00642	COG1668	transmembrane transport
C7M29_00643	COG4555	ABC transporter
C7M29_00644	COG3279	Response regulator of the LytR AlgR family
C7M29_00645	COG3290	protein histidine kinase activity
C7M29_00646	COG3012	SEC-C Motif Domain Protein
C7M29_00646	COG1405	negative regulation of cell septum assembly
C7M29_00647	COG1714	RDD family
C7M29_00648	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M29_00649	COG0252	asparaginase activity
C7M29_00650	COG1309	transcriptional regulator
C7M29_00651	COG0477	Major facilitator Superfamily
C7M29_00652	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M29_00653	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7M29_00654	COG0805	protein transport
C7M29_00655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M29_00656	COG3540	Alkaline phosphatase
C7M29_00657	COG2304	oxidoreductase activity
C7M29_00658	COG3773	Cell wall hydrolase
C7M29_00661	COG1131	(ABC) transporter
C7M29_00662	COG2205	protein histidine kinase activity
C7M29_00663	COG0745	RESPONSE REGULATOR receiver
C7M29_00664	COG0697	spore germination
C7M29_00666	COG3173	Aminoglycoside phosphotransferase
C7M29_00667	COG2721	sulfolactate sulfo-lyase activity
C7M29_00668	COG2186	Transcriptional regulator
C7M29_00669	COG4948	Mandelate Racemase Muconate Lactonizing
C7M29_00670	COG2271	Major facilitator Superfamily
C7M29_00671	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_00672	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M29_00673	COG0784	Response regulator, receiver
C7M29_00674	COG4191	Histidine kinase
C7M29_00675	COG2066	Belongs to the glutaminase family
C7M29_00676	COG1115	amino acid carrier protein
C7M29_00677	COG2040	homocysteine
C7M29_00678	COG0833	amino acid
C7M29_00679	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M29_00681	COG2188	Transcriptional regulator
C7M29_00682	COG0363	glucosamine-6-phosphate deaminase activity
C7M29_00683	COG1263	PTS System
C7M29_00683	COG2190	(PTS) system
C7M29_00683	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_00684	COG1301	dicarboxylic acid transport
C7M29_00686	COG2207	Transcriptional regulator
C7M29_00687	COG2312	Erythromycin esterase
C7M29_00689	COG0688	phosphatidylethanolamine metabolic process
C7M29_00690	COG0586	Pfam SNARE associated Golgi protein
C7M29_00691	COG1183	phosphatidylcholine synthase activity
C7M29_00692	COG0596	Alpha beta hydrolase
C7M29_00694	COG3591	Belongs to the peptidase S1B family
C7M29_00695	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7M29_00696	COG1917	Cupin 2, conserved barrel domain protein
C7M29_00696	COG2207	Transcriptional regulator
C7M29_00697	COG0697	spore germination
C7M29_00698	COG3409	Peptidoglycan-binding domain 1 protein
C7M29_00700	COG2271	Major facilitator Superfamily
C7M29_00701	COG1846	Transcriptional regulator
C7M29_00701	COG0456	acetyltransferase
C7M29_00703	COG2271	Major facilitator Superfamily
C7M29_00704	COG0584	glycerophosphoryl diester phosphodiesterase
C7M29_00705	COG0531	amino acid
C7M29_00707	COG2124	cytochrome p450
C7M29_00708	COG2602	Beta-lactamase
C7M29_00711	COG1113	amino acid transport
C7M29_00714	COG0515	serine threonine protein kinase
C7M29_00716	COG0642	Histidine kinase
C7M29_00717	COG0745	RESPONSE REGULATOR receiver
C7M29_00718	COG0596	Alpha beta hydrolase
C7M29_00720	COG2814	Major facilitator Superfamily
C7M29_00721	COG0640	Transcriptional regulator
C7M29_00722	COG5609	conserved protein (DUF2294)
C7M29_00724	COG0288	reversible hydration of carbon dioxide
C7M29_00725	COG3002	Belongs to the UPF0753 family
C7M29_00726	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M29_00727	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M29_00728	COG2169	Transcriptional regulator
C7M29_00729	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M29_00730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M29_00731	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M29_00732	COG4856	YbbR-like protein
C7M29_00733	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M29_00734	COG5662	AntiSigma factor
C7M29_00735	COG1595	DNA-templated transcription, initiation
C7M29_00741	COG1683	Conserved Protein
C7M29_00742	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M29_00743	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M29_00744	COG1737	Transcriptional regulator
C7M29_00745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_00745	COG1263	PTS System
C7M29_00746	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M29_00747	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M29_00748	COG3876	Protein conserved in bacteria
C7M29_00749	COG2207	Transcriptional regulator
C7M29_00749	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M29_00750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M29_00751	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M29_00752	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M29_00753	COG2819	hydrolase of the alpha beta superfamily
C7M29_00754	COG0385	Bile acid
C7M29_00756	COG0659	secondary active sulfate transmembrane transporter activity
C7M29_00769	COG5444	nuclease activity
C7M29_00772	COG3778	Protein conserved in bacteria
C7M29_00789	COG0726	polysaccharide deacetylase
C7M29_00790	COG2194	sulfuric ester hydrolase activity
C7M29_00792	COG0489	protein tyrosine kinase activity
C7M29_00793	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M29_00795	COG2226	methyltransferase
C7M29_00796	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7M29_00797	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7M29_00798	COG0101	tRNA pseudouridine synthase activity
C7M29_00799	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M29_00800	COG1122	ATPase activity
C7M29_00801	COG1122	ATPase activity
C7M29_00802	COG0203	ribosomal protein L17
C7M29_00803	COG0202	RNA polymerase activity
C7M29_00804	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7M29_00805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7M29_00806	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M29_00808	COG0024	Methionine aminopeptidase
C7M29_00809	COG0563	adenylate kinase activity
C7M29_00810	COG0201	protein transport
C7M29_00811	COG0200	Binds to the 23S rRNA
C7M29_00814	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7M29_00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7M29_00816	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7M29_00818	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7M29_00820	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7M29_00821	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7M29_00823	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M29_00827	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7M29_00829	COG0088	Forms part of the polypeptide exit tunnel
C7M29_00830	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7M29_00832	COG0596	Alpha beta hydrolase
C7M29_00833	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7M29_00834	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7M29_00835	COG0049	tRNA binding
C7M29_00836	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7M29_00837	COG1358	cellular component organization or biogenesis
C7M29_00838	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7M29_00839	COG0085	RNA polymerase activity
C7M29_00840	COG2813	Specifically methylates the guanine in position
C7M29_00842	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7M29_00843	COG0081	regulation of translation
C7M29_00845	COG0250	Participates in transcription elongation, termination and antitermination
C7M29_00846	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M29_00847	COG1595	DNA-templated transcription, initiation
C7M29_00848	COG3688	RNA-binding protein containing a PIN domain
C7M29_00849	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M29_00850	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M29_00851	COG0215	cysteine-tRNA ligase activity
C7M29_00852	COG1045	serine acetyltransferase
C7M29_00853	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7M29_00854	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7M29_00855	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7M29_00856	COG4956	integral membrane protein (PIN domain superfamily)
C7M29_00857	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C7M29_00858	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7M29_00859	COG0542	response to heat
C7M29_00860	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C7M29_00861	COG3880	PFAM UvrB UvrC protein
C7M29_00862	COG4463	regulation of RNA biosynthetic process
C7M29_00878	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M29_00879	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M29_00880	COG1396	sequence-specific DNA binding
C7M29_00881	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M29_00882	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7M29_00883	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7M29_00884	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M29_00885	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M29_00886	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M29_00887	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M29_00888	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M29_00889	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7M29_00890	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C7M29_00891	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M29_00893	COG0037	tRNA processing
C7M29_00894	COG0515	serine threonine protein kinase
C7M29_00895	COG2304	oxidoreductase activity
C7M29_00896	COG2208	phosphoserine phosphatase activity
C7M29_00899	COG1098	S1 RNA binding domain
C7M29_00900	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7M29_00903	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M29_00904	COG3956	TIGRFAM MazG family protein
C7M29_00905	COG2244	polysaccharide biosynthetic process
C7M29_00906	COG2002	toxin-antitoxin pair type II binding
C7M29_00907	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M29_00909	COG0193	aminoacyl-tRNA hydrolase activity
C7M29_00910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7M29_00911	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M29_00912	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7M29_00913	COG2088	sporulation resulting in formation of a cellular spore
C7M29_00914	COG0251	oxidation-reduction process
C7M29_00915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M29_00916	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7M29_00917	COG4466	Protein conserved in bacteria
C7M29_00919	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M29_00920	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M29_00921	COG3583	domain protein
C7M29_00921	COG3584	3D domain protein
C7M29_00922	COG0084	hydrolase, TatD family'
C7M29_00923	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M29_00923	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M29_00924	COG2002	toxin-antitoxin pair type II binding
C7M29_00925	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7M29_00926	COG2827	Endonuclease containing a URI domain
C7M29_00927	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M29_00928	COG4467	Involved in initiation control of chromosome replication
C7M29_00929	COG1774	PSP1 C-terminal conserved region
C7M29_00930	COG0470	DNA polymerase III
C7M29_00931	COG1728	Protein conserved in bacteria
C7M29_00932	COG3870	Protein conserved in bacteria
C7M29_00933	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M29_00934	COG1982	Orn Lys Arg decarboxylase major
C7M29_00935	COG3853	Toxic anion resistance protein (TelA)
C7M29_00936	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C7M29_00945	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7M29_00946	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M29_00947	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M29_00948	COG0590	tRNA wobble adenosine to inosine editing
C7M29_00949	COG1335	isochorismatase
C7M29_00950	COG1388	LysM domain
C7M29_00950	COG3858	chitin binding
C7M29_00951	COG1428	Deoxynucleoside kinase
C7M29_00952	COG1428	Deoxynucleoside kinase
C7M29_00954	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M29_00955	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C7M29_00956	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C7M29_00957	COG1686	Belongs to the peptidase S11 family
C7M29_00958	COG0517	IMP dehydrogenase activity
C7M29_00958	COG0516	GMP reductase activity
C7M29_00965	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M29_00966	COG0187	DNA topoisomerase II activity
C7M29_00968	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7M29_00969	COG2501	S4 domain
C7M29_00970	COG0592	DNA-directed DNA polymerase activity
C7M29_00971	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7M29_00972	COG0594	ribonuclease P activity
C7M29_00973	COG0706	membrane insertase activity
C7M29_00974	COG1847	R3H domain protein
C7M29_00975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7M29_00976	COG0445	tRNA wobble uridine modification
C7M29_00977	COG0357	Ribosomal RNA small subunit methyltransferase G
C7M29_00978	COG1475	DNA binding
C7M29_00980	COG1192	Involved in chromosome partitioning
C7M29_00981	COG1475	DNA binding
C7M29_00983	COG3949	Membrane
C7M29_00984	COG4481	Protein conserved in bacteria
C7M29_00985	COG0243	molybdopterin cofactor binding
C7M29_00986	COG0012	GTP binding
C7M29_00987	COG0360	Binds together with S18 to 16S ribosomal RNA
C7M29_00988	COG0629	single-stranded DNA binding
C7M29_00989	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7M29_00990	COG0708	Exodeoxyribonuclease III
C7M29_00991	COG1609	Transcriptional regulator
C7M29_00992	COG0346	lactoylglutathione lyase activity
C7M29_00993	COG0110	maltose O-acetyltransferase activity
C7M29_00994	COG0477	Major facilitator Superfamily
C7M29_00994	COG2814	Major facilitator Superfamily
C7M29_00995	COG1266	CAAX protease self-immunity
C7M29_00996	COG1331	Highly conserved protein containing a thioredoxin domain
C7M29_00997	COG1331	Highly conserved protein containing a thioredoxin domain
C7M29_00998	COG1280	lysine exporter protein (LysE YggA)
C7M29_00999	COG1902	pentaerythritol trinitrate reductase activity
C7M29_01000	COG1309	transcriptional regulator
C7M29_01002	COG1733	regulation of RNA biosynthetic process
C7M29_01004	COG1331	Highly conserved protein containing a thioredoxin domain
C7M29_01005	COG2814	Major facilitator Superfamily
C7M29_01006	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M29_01007	COG2315	Protein conserved in bacteria
C7M29_01008	COG0456	acetyltransferase
C7M29_01009	COG2364	Membrane
C7M29_01010	COG2153	protein acetylation
C7M29_01011	COG1846	Transcriptional regulator
C7M29_01012	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M29_01014	COG2153	protein acetylation
C7M29_01015	COG0583	DNA-binding transcription factor activity
C7M29_01016	COG2814	Major facilitator Superfamily
C7M29_01017	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M29_01018	COG4319	ketosteroid isomerase
C7M29_01020	COG0789	Transcriptional regulator
C7M29_01020	COG4978	Transcriptional regulator
C7M29_01021	COG2271	Major facilitator Superfamily
C7M29_01024	COG1227	inorganic diphosphatase activity
C7M29_01025	COG1733	regulation of RNA biosynthetic process
C7M29_01026	COG5577	PFAM Coat F domain
C7M29_01028	COG4241	membrane
C7M29_01029	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7M29_01030	COG0359	binds to the 23S rRNA
C7M29_01031	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M29_01032	COG2807	transmembrane transport
C7M29_01033	COG3093	addiction module antidote protein HigA
C7M29_01036	COG0305	Participates in initiation and elongation during chromosome replication
C7M29_01037	COG0346	lactoylglutathione lyase activity
C7M29_01043	COG0745	RESPONSE REGULATOR receiver
C7M29_01044	COG5002	protein histidine kinase activity
C7M29_01045	COG4863	YycH protein
C7M29_01046	COG4853	Protein conserved in bacteria
C7M29_01047	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M29_01048	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M29_01052	COG5002	protein histidine kinase activity
C7M29_01053	COG3829	transcription factor binding
C7M29_01054	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M29_01055	COG0833	amino acid
C7M29_01056	COG0010	Belongs to the arginase family
C7M29_01058	COG0457	Tetratricopeptide repeat
C7M29_01059	COG0456	acetyltransferase
C7M29_01060	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C7M29_01064	COG1063	alcohol dehydrogenase
C7M29_01067	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7M29_01071	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C7M29_01073	COG0535	radical SAM domain protein
C7M29_01074	COG1994	Peptidase M50
C7M29_01075	COG1131	(ABC) transporter
C7M29_01078	COG2188	Transcriptional regulator
C7M29_01079	COG1263	PTS System
C7M29_01079	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_01079	COG2190	(PTS) system
C7M29_01080	COG2723	6-phospho-beta-galactosidase activity
C7M29_01081	COG3634	alkyl hydroperoxide reductase activity
C7M29_01082	COG0450	alkyl hydroperoxide reductase
C7M29_01083	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M29_01084	COG2610	gluconate transmembrane transporter activity
C7M29_01085	COG1070	Carbohydrate kinase
C7M29_01086	COG1802	Transcriptional regulator
C7M29_01087	COG1929	Belongs to the glycerate kinase type-1 family
C7M29_01088	COG5039	Polysaccharide pyruvyl transferase
C7M29_01089	COG1346	cytolysis
C7M29_01090	COG1380	Effector of murein hydrolase LrgA
C7M29_01091	COG1846	Transcriptional regulator
C7M29_01092	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01093	COG1309	transcriptional regulator
C7M29_01094	COG1917	Cupin 2, conserved barrel domain protein
C7M29_01095	COG2311	Membrane
C7M29_01096	COG1714	RDD family
C7M29_01098	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7M29_01099	COG2814	Major facilitator Superfamily
C7M29_01100	COG0367	asparagine synthase
C7M29_01103	COG2226	methyltransferase
C7M29_01104	COG2850	peptidyl-arginine hydroxylation
C7M29_01105	COG0456	acetyltransferase
C7M29_01106	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_01107	COG1309	transcriptional regulator
C7M29_01108	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01110	COG0326	Molecular chaperone. Has ATPase activity
C7M29_01111	COG2814	Major facilitator Superfamily
C7M29_01114	COG0667	Aldo Keto reductase
C7M29_01115	COG1349	DNA-binding transcription factor activity
C7M29_01116	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_01118	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M29_01119	COG3962	Belongs to the TPP enzyme family
C7M29_01120	COG1082	Xylose isomerase domain protein TIM barrel
C7M29_01121	COG2814	Major facilitator Superfamily
C7M29_01122	COG0673	inositol 2-dehydrogenase activity
C7M29_01123	COG1082	Xylose isomerase domain protein TIM barrel
C7M29_01124	COG1082	Xylose isomerase domain protein TIM barrel
C7M29_01125	COG0191	fructose-bisphosphate aldolase activity
C7M29_01126	COG0745	RESPONSE REGULATOR receiver
C7M29_01127	COG2205	protein histidine kinase activity
C7M29_01128	COG1136	(ABC) transporter
C7M29_01129	COG0577	efflux transmembrane transporter activity
C7M29_01130	COG5294	Protein conserved in bacteria
C7M29_01131	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M29_01137	COG0561	phosphatase activity
C7M29_01138	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M29_01139	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M29_01140	COG0456	acetyltransferase
C7M29_01141	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M29_01142	COG0765	amino acid transport
C7M29_01143	COG1126	abc transporter atp-binding protein
C7M29_01144	COG1473	amidohydrolase
C7M29_01145	COG2079	MmgE PrpD family protein
C7M29_01146	COG3192	ethanolamine utilization protein
C7M29_01148	COG2390	Transcriptional regulator
C7M29_01149	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7M29_01150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M29_01151	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7M29_01152	COG0833	amino acid
C7M29_01153	COG0010	Belongs to the arginase family
C7M29_01154	COG1228	amidohydrolase
C7M29_01155	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C7M29_01156	COG2986	histidine ammonia-lyase
C7M29_01158	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M29_01161	COG5444	nuclease activity
C7M29_01164	COG2190	(PTS) system
C7M29_01164	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_01164	COG1263	PTS System
C7M29_01165	COG2723	6-phospho-beta-galactosidase activity
C7M29_01166	COG0589	response to stress
C7M29_01170	COG0789	Transcriptional regulator
C7M29_01171	COG0697	spore germination
C7M29_01184	COG3401	FG-GAP repeat protein
C7M29_01184	COG2755	lipolytic protein G-D-S-L family
C7M29_01185	COG0513	Belongs to the DEAD box helicase family
C7M29_01186	COG2270	Major facilitator Superfamily
C7M29_01188	COG3711	transcriptional antiterminator
C7M29_01189	COG2273	Hydrolase Family 16
C7M29_01190	COG2851	Citrate transporter
C7M29_01191	COG0693	protein deglycase activity
C7M29_01191	COG0753	catalase activity
C7M29_01194	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M29_01195	COG0500	methyltransferase
C7M29_01196	COG2610	gluconate transmembrane transporter activity
C7M29_01197	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M29_01198	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M29_01199	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M29_01201	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M29_01202	COG4894	glucomannan catabolic process
C7M29_01204	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M29_01205	COG2197	response regulator
C7M29_01206	COG4585	Histidine kinase
C7M29_01208	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M29_01210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M29_01211	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_01212	COG2508	Transcriptional regulator
C7M29_01213	COG3842	ATPase activity
C7M29_01214	COG0726	polysaccharide deacetylase
C7M29_01216	COG0501	Belongs to the peptidase M48B family
C7M29_01217	COG3493	citrate carrier protein
C7M29_01218	COG1271	oxidase subunit
C7M29_01219	COG1294	oxidase, subunit
C7M29_01220	COG4988	ABC transporter
C7M29_01221	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M29_01222	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M29_01223	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M29_01224	COG1595	DNA-templated transcription, initiation
C7M29_01228	COG1131	(ABC) transporter
C7M29_01229	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M29_01230	COG2814	Major facilitator Superfamily
C7M29_01231	COG0753	catalase activity
C7M29_01232	COG2094	Belongs to the DNA glycosylase MPG family
C7M29_01234	COG3711	transcriptional antiterminator
C7M29_01234	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M29_01235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M29_01236	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M29_01237	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M29_01238	COG1486	melibiose metabolic process
C7M29_01239	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M29_01240	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7M29_01241	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M29_01242	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M29_01243	COG1696	Membrane protein involved in D-alanine export
C7M29_01244	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_01245	COG1575	Belongs to the MenA family. Type 1 subfamily
C7M29_01246	COG2357	RelA SpoT domain protein
C7M29_01247	COG2814	Major facilitator Superfamily
C7M29_01250	COG2234	aminopeptidase activity
C7M29_01251	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M29_01252	COG1846	Transcriptional regulator
C7M29_01253	COG5522	Integral membrane protein (intg_mem_TP0381)
C7M29_01254	COG1442	glycosyl transferase family 8
C7M29_01255	COG3711	transcriptional antiterminator
C7M29_01256	COG1263	PTS System
C7M29_01256	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_01257	COG1404	Belongs to the peptidase S8 family
C7M29_01258	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M29_01259	COG0346	lactoylglutathione lyase activity
C7M29_01260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M29_01261	COG4895	conserved protein (DUF2196)
C7M29_01262	COG2814	Major facilitator Superfamily
C7M29_01263	COG1346	cytolysis
C7M29_01264	COG1380	Effector of murein hydrolase LrgA
C7M29_01265	COG0583	DNA-binding transcription factor activity
C7M29_01266	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7M29_01267	COG0352	thiamine-phosphate diphosphorylase activity
C7M29_01268	COG0672	)-iron permease
C7M29_01269	COG2822	iron ion transport
C7M29_01270	COG2837	iron assimilation
C7M29_01271	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M29_01272	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M29_01273	COG3162	membrane
C7M29_01275	COG1309	transcriptional regulator
C7M29_01276	COG2246	polysaccharide biosynthetic process
C7M29_01277	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M29_01278	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M29_01279	COG2261	transglycosylase associated protein
C7M29_01280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M29_01281	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M29_01282	COG1845	cytochrome c oxidase, subunit III
C7M29_01283	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M29_01285	COG0772	Belongs to the SEDS family
C7M29_01286	COG0778	Nitroreductase
C7M29_01287	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M29_01288	COG1404	Belongs to the peptidase S8 family
C7M29_01290	COG3711	transcriptional antiterminator
C7M29_01291	COG2116	formate transmembrane transporter activity
C7M29_01292	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_01292	COG1263	PTS System
C7M29_01293	COG1621	beta-fructofuranosidase activity
C7M29_01295	COG0351	phosphomethylpyrimidine kinase
C7M29_01296	COG1695	Transcriptional regulator
C7M29_01299	COG1216	Glycosyl transferase, family 2
C7M29_01300	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7M29_01301	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_01303	COG2233	PERMEase
C7M29_01304	COG2363	Small membrane protein
C7M29_01306	COG0463	Glycosyl transferase, family 2
C7M29_01307	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M29_01308	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M29_01309	COG0456	acetyltransferase
C7M29_01310	COG2089	acid synthase
C7M29_01311	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C7M29_01312	COG3980	spore coat polysaccharide biosynthesis protein
C7M29_01313	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C7M29_01314	COG1088	dTDP-glucose 4,6-dehydratase activity
C7M29_01315	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7M29_01316	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C7M29_01318	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M29_01319	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_01320	COG4187	Peptidase family M20/M25/M40
C7M29_01321	COG0833	amino acid
C7M29_01322	COG2814	Major facilitator Superfamily
C7M29_01323	COG0077	Prephenate dehydratase
C7M29_01324	COG1917	Cupin 2, conserved barrel domain protein
C7M29_01325	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01326	COG0151	Belongs to the GarS family
C7M29_01327	COG2814	Major facilitator Superfamily
C7M29_01328	COG0436	Aminotransferase
C7M29_01329	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01331	COG0280	phosphate acetyltransferase
C7M29_01332	COG0583	DNA-binding transcription factor activity
C7M29_01333	COG0095	Lipoate-protein ligase
C7M29_01334	COG0697	spore germination
C7M29_01336	COG4844	belongs to the
C7M29_01337	COG1078	dGTPase activity
C7M29_01338	COG3465	dGTPase activity
C7M29_01339	COG1959	2 iron, 2 sulfur cluster binding
C7M29_01340	COG0477	Major facilitator Superfamily
C7M29_01342	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M29_01343	COG1846	Transcriptional regulator
C7M29_01344	COG1942	4-Oxalocrotonate Tautomerase
C7M29_01345	COG1994	Peptidase M50
C7M29_01347	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M29_01348	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7M29_01349	COG0010	Belongs to the arginase family
C7M29_01350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M29_01352	COG0457	Tetratricopeptide repeat
C7M29_01353	COG3391	amine dehydrogenase activity
C7M29_01354	COG3391	amine dehydrogenase activity
C7M29_01356	COG0612	Peptidase, M16
C7M29_01357	COG0612	Peptidase, M16
C7M29_01358	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M29_01359	COG1131	(ABC) transporter
C7M29_01361	COG0535	radical SAM domain protein
C7M29_01363	COG4506	Protein conserved in bacteria
C7M29_01364	COG0018	arginyl-trna synthetase
C7M29_01365	COG2223	nitrite transmembrane transporter activity
C7M29_01366	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M29_01368	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M29_01369	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M29_01370	COG1140	nitrate reductase beta subunit
C7M29_01371	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7M29_01372	COG2181	nitrate reductase activity
C7M29_01373	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M29_01374	COG1132	(ABC) transporter
C7M29_01375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M29_01377	COG4294	response to UV
C7M29_01378	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M29_01379	COG2181	nitrate reductase activity
C7M29_01379	COG0247	lactate metabolic process
C7M29_01380	COG1960	acyl-CoA dehydrogenase activity
C7M29_01381	COG3343	RNA polymerase activity
C7M29_01382	COG0504	CTP synthase activity
C7M29_01383	COG4821	SIS domain
C7M29_01384	COG2204	response regulator
C7M29_01385	COG0191	fructose-bisphosphate aldolase activity
C7M29_01386	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7M29_01387	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M29_01388	COG1494	fructose-1,6-bisphosphatase
C7M29_01389	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M29_01391	COG1435	thymidine kinase activity
C7M29_01392	COG0281	malic enzyme
C7M29_01393	COG0679	Auxin Efflux Carrier
C7M29_01394	COG0789	Transcriptional regulator
C7M29_01395	COG0346	lactoylglutathione lyase activity
C7M29_01396	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M29_01397	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M29_01401	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7M29_01402	COG0009	L-threonylcarbamoyladenylate synthase
C7M29_01403	COG1971	Probably functions as a manganese efflux pump
C7M29_01404	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M29_01405	COG0698	ribose 5-phosphate isomerase
C7M29_01406	COG4475	Protein of unknown function (DUF436)
C7M29_01407	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7M29_01408	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7M29_01410	COG0356	it plays a direct role in the translocation of protons across the membrane
C7M29_01412	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7M29_01413	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M29_01414	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7M29_01415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7M29_01416	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7M29_01417	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7M29_01419	COG4836	Membrane
C7M29_01421	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M29_01422	COG2385	sporulation resulting in formation of a cellular spore
C7M29_01423	COG2304	oxidoreductase activity
C7M29_01424	COG2304	oxidoreductase activity
C7M29_01426	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7M29_01427	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7M29_01428	COG0457	Tetratricopeptide repeat
C7M29_01429	COG1994	Peptidase M50
C7M29_01430	COG3237	CsbD-like
C7M29_01431	COG0831	urea catabolic process
C7M29_01432	COG0832	Belongs to the urease beta subunit family
C7M29_01433	COG0804	urea catabolic process
C7M29_01434	COG1959	2 iron, 2 sulfur cluster binding
C7M29_01435	COG2910	NAD(P)H-binding
C7M29_01437	COG0789	Transcriptional regulator
C7M29_01438	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M29_01441	COG1247	-acetyltransferase
C7M29_01442	COG0739	heme binding
C7M29_01444	COG0671	phosphoesterase, PA-phosphatase related
C7M29_01445	COG0347	Belongs to the P(II) protein family
C7M29_01446	COG0004	ammonium transporteR
C7M29_01448	COG1335	isochorismatase
C7M29_01449	COG0477	Major facilitator Superfamily
C7M29_01450	COG1953	Uracil, thiamine, allantoin
C7M29_01451	COG3420	alginic acid biosynthetic process
C7M29_01452	COG2814	Major facilitator Superfamily
C7M29_01453	COG1846	Transcriptional regulator
C7M29_01454	COG1609	Transcriptional regulator
C7M29_01455	COG1077	Cell shape determining protein MreB Mrl
C7M29_01456	COG4786	Flagellar basal body rod
C7M29_01457	COG4786	Flagellar basal body rod
C7M29_01458	COG0457	Tetratricopeptide repeat
C7M29_01459	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M29_01460	COG1970	mechanosensitive ion channel activity
C7M29_01461	COG2972	Histidine kinase
C7M29_01461	COG0745	RESPONSE REGULATOR receiver
C7M29_01462	COG3764	Sortase (surface protein transpeptidase)
C7M29_01465	COG0629	single-stranded DNA binding
C7M29_01466	COG1349	DNA-binding transcription factor activity
C7M29_01467	COG0561	phosphatase activity
C7M29_01468	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M29_01469	COG4715	Zinc finger, swim domain protein
C7M29_01471	COG3944	biosynthesis protein
C7M29_01472	COG0489	protein tyrosine kinase activity
C7M29_01473	COG4464	protein tyrosine phosphatase activity
C7M29_01474	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M29_01475	COG3878	Protein conserved in bacteria
C7M29_01478	COG5444	nuclease activity
C7M29_01481	COG5444	nuclease activity
C7M29_01486	COG1515	deoxyribonuclease V activity
C7M29_01487	COG0583	DNA-binding transcription factor activity
C7M29_01488	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M29_01490	COG2059	Chromate
C7M29_01491	COG2059	Chromate
C7M29_01492	COG1522	sequence-specific DNA binding
C7M29_01493	COG0405	Gamma-glutamyltransferase
C7M29_01495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M29_01497	COG5337	Spore coat protein CotH
C7M29_01500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M29_01501	COG0583	DNA-binding transcription factor activity
C7M29_01502	COG0028	Belongs to the TPP enzyme family
C7M29_01503	COG3527	Alpha-acetolactate decarboxylase
C7M29_01504	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M29_01506	COG3103	Sh3 type 3 domain protein
C7M29_01507	COG1879	ABC-type sugar transport system periplasmic component
C7M29_01508	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7M29_01509	COG1129	ABC transporter
C7M29_01510	COG1869	D-ribose catabolic process
C7M29_01511	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M29_01512	COG1609	Transcriptional regulator
C7M29_01513	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M29_01515	COG2843	Capsule synthesis protein
C7M29_01517	COG0791	NLP P60 protein
C7M29_01518	COG0561	phosphatase activity
C7M29_01519	COG1316	TRANSCRIPTIONal
C7M29_01520	COG2814	Major facilitator Superfamily
C7M29_01522	COG0814	amino acid
C7M29_01523	COG0697	spore germination
C7M29_01524	COG1482	cell wall glycoprotein biosynthetic process
C7M29_01525	COG4193	domain, Protein
C7M29_01527	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M29_01528	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C7M29_01529	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M29_01530	COG0438	transferase activity, transferring glycosyl groups
C7M29_01531	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M29_01532	COG1682	transport, permease protein
C7M29_01533	COG1134	teichoic acid transport
C7M29_01534	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M29_01535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M29_01537	COG0463	Glycosyl transferase, family 2
C7M29_01538	COG1215	transferase activity, transferring glycosyl groups
C7M29_01538	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M29_01540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M29_01541	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M29_01542	COG1316	TRANSCRIPTIONal
C7M29_01544	COG2385	sporulation resulting in formation of a cellular spore
C7M29_01544	COG2247	cell wall binding repeat
C7M29_01545	COG2247	cell wall binding repeat
C7M29_01545	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M29_01547	COG2244	polysaccharide biosynthetic process
C7M29_01548	COG0438	transferase activity, transferring glycosyl groups
C7M29_01548	COG0297	glycogen (starch) synthase activity
C7M29_01549	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M29_01550	COG3307	-O-antigen
C7M29_01551	COG3206	protein involved in exopolysaccharide biosynthesis
C7M29_01552	COG1215	transferase activity, transferring glycosyl groups
C7M29_01553	COG0438	transferase activity, transferring glycosyl groups
C7M29_01554	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M29_01555	COG1316	TRANSCRIPTIONal
C7M29_01556	COG1739	Uncharacterized protein family UPF0029
C7M29_01557	COG4585	Histidine kinase
C7M29_01558	COG2197	response regulator
C7M29_01559	COG1307	EDD domain protein, DegV family
C7M29_01560	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M29_01562	COG1040	competence protein
C7M29_01564	COG2747	anti-sigma28 factor FlgM
C7M29_01565	COG3418	PFAM FlgN family protein
C7M29_01566	COG1256	bacterial-type flagellum assembly
C7M29_01566	COG4786	Flagellar basal body rod
C7M29_01567	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M29_01569	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C7M29_01570	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C7M29_01571	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M29_01572	COG1334	flagellar protein FlaG
C7M29_01573	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7M29_01574	COG1516	flagellar protein fliS
C7M29_01577	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7M29_01578	COG0653	protein targeting
C7M29_01579	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C7M29_01580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M29_01581	COG2010	Cytochrome c
C7M29_01582	COG2884	Cell division ATP-binding protein ftsE
C7M29_01583	COG2177	Part of the ABC transporter FtsEX involved in
C7M29_01584	COG0793	Belongs to the peptidase S41A family
C7M29_01584	COG3409	Peptidoglycan-binding domain 1 protein
C7M29_01586	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M29_01587	COG2814	Major facilitator Superfamily
C7M29_01588	COG1309	transcriptional regulator
C7M29_01589	COG0574	Belongs to the PEP-utilizing enzyme family
C7M29_01589	COG3848	Pyruvate phosphate dikinase
C7M29_01590	COG4897	Protein conserved in bacteria
C7M29_01591	COG0556	nucleotide-excision repair
C7M29_01592	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M29_01593	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M29_01596	COG3595	metallopeptidase activity
C7M29_01597	COG1983	PspC domain protein
C7M29_01598	COG1950	PFAM Membrane protein of
C7M29_01599	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M29_01600	COG2188	Transcriptional regulator
C7M29_01601	COG0363	glucosamine-6-phosphate deaminase activity
C7M29_01602	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7M29_01603	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7M29_01604	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7M29_01605	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7M29_01606	COG0546	phosphoglycolate phosphatase activity
C7M29_01607	COG0110	maltose O-acetyltransferase activity
C7M29_01608	COG5297	Belongs to the glycosyl hydrolase family 6
C7M29_01609	COG4990	cell redox homeostasis
C7M29_01610	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7M29_01611	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7M29_01612	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M29_01613	COG0131	Imidazoleglycerol-phosphate dehydratase
C7M29_01614	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7M29_01615	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7M29_01616	COG0107	imidazoleglycerol-phosphate synthase activity
C7M29_01617	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M29_01617	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M29_01621	COG1132	(ABC) transporter
C7M29_01622	COG0457	Tetratricopeptide repeat
C7M29_01623	COG0791	NLP P60 protein
C7M29_01623	COG3883	PFAM NLP P60 protein
C7M29_01624	COG0492	ferredoxin-NADP+ reductase activity
C7M29_01625	COG1051	belongs to the nudix hydrolase family
C7M29_01626	COG1660	Displays ATPase and GTPase activities
C7M29_01627	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M29_01628	COG1481	regulation of sporulation
C7M29_01629	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M29_01630	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7M29_01632	COG0745	RESPONSE REGULATOR receiver
C7M29_01633	COG5002	protein histidine kinase activity
C7M29_01634	COG1136	(ABC) transporter
C7M29_01635	COG0577	efflux transmembrane transporter activity
C7M29_01636	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M29_01637	COG0288	reversible hydration of carbon dioxide
C7M29_01638	COG0659	secondary active sulfate transmembrane transporter activity
C7M29_01639	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M29_01640	COG1611	Belongs to the LOG family
C7M29_01641	COG1609	Transcriptional regulator
C7M29_01643	COG2182	Extracellular solute-binding protein
C7M29_01644	COG1175	transmembrane transport
C7M29_01645	COG3833	ABC-type maltose transport systems, permease component
C7M29_01646	COG5521	maltodextrose utilization protein MalA
C7M29_01647	COG1554	hydrolase, family 65, central catalytic
C7M29_01648	COG0366	Alpha amylase catalytic
C7M29_01649	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M29_01650	COG0740	serine-type endopeptidase activity
C7M29_01652	COG3621	Patatin-like phospholipase
C7M29_01653	COG0277	FAD linked oxidase domain protein
C7M29_01655	COG2076	Multidrug Resistance protein
C7M29_01656	COG2076	Multidrug Resistance protein
C7M29_01657	COG1309	transcriptional regulator
C7M29_01658	COG0531	amino acid
C7M29_01659	COG1621	beta-fructofuranosidase activity
C7M29_01660	COG1621	beta-fructofuranosidase activity
C7M29_01661	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M29_01662	COG1794	racemase activity, acting on amino acids and derivatives
C7M29_01664	COG3479	Phenolic acid decarboxylase
C7M29_01666	COG2272	Belongs to the type-B carboxylesterase lipase family
C7M29_01667	COG1396	sequence-specific DNA binding
C7M29_01668	COG3944	biosynthesis protein
C7M29_01669	COG0489	protein tyrosine kinase activity
C7M29_01670	COG1086	Polysaccharide biosynthesis protein
C7M29_01671	COG0438	transferase activity, transferring glycosyl groups
C7M29_01672	COG1215	transferase activity, transferring glycosyl groups
C7M29_01673	COG0438	transferase activity, transferring glycosyl groups
C7M29_01675	COG1216	Glycosyl transferase, family 2
C7M29_01676	COG5039	Polysaccharide pyruvyl transferase
C7M29_01677	COG1216	Glycosyl transferase, family 2
C7M29_01678	COG2244	polysaccharide biosynthetic process
C7M29_01679	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M29_01680	COG0110	maltose O-acetyltransferase activity
C7M29_01681	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M29_01682	COG5039	Polysaccharide pyruvyl transferase
C7M29_01684	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M29_01685	COG1620	l-lactate permease
C7M29_01686	COG2186	Transcriptional regulator
C7M29_01687	COG1609	Transcriptional regulator
C7M29_01688	COG2182	Extracellular solute-binding protein
C7M29_01689	COG1175	transmembrane transport
C7M29_01690	COG3833	ABC-type maltose transport systems, permease component
C7M29_01691	COG1874	Beta-galactosidase
C7M29_01692	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C7M29_01693	COG2208	phosphoserine phosphatase activity
C7M29_01694	COG0596	Alpha beta hydrolase
C7M29_01695	COG1131	(ABC) transporter
C7M29_01696	COG0842	Transport permease protein
C7M29_01697	COG4585	Histidine kinase
C7M29_01698	COG2197	response regulator
C7M29_01699	COG0247	lactate metabolic process
C7M29_01700	COG1139	Iron-sulfur cluster binding protein
C7M29_01701	COG1556	Lactate utilization protein
C7M29_01702	COG3858	chitin binding
C7M29_01703	COG1113	amino acid transport
C7M29_01704	COG0697	spore germination
C7M29_01705	COG0583	DNA-binding transcription factor activity
C7M29_01706	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M29_01707	COG1609	Transcriptional regulator
C7M29_01708	COG2814	Major facilitator Superfamily
C7M29_01709	COG2390	Transcriptional regulator
C7M29_01710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M29_01711	COG0126	phosphoglycerate kinase activity
C7M29_01712	COG0149	triose-phosphate isomerase activity
C7M29_01713	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7M29_01714	COG0148	phosphopyruvate hydratase activity
C7M29_01715	COG0456	acetyltransferase
C7M29_01716	COG4640	response to antibiotic
C7M29_01717	COG3064	Membrane
C7M29_01719	COG2095	MarC family integral membrane protein
C7M29_01720	COG1510	regulation of RNA biosynthetic process
C7M29_01721	COG1125	glycine betaine transport
C7M29_01721	COG0517	IMP dehydrogenase activity
C7M29_01722	COG1174	glycine betaine transport
C7M29_01723	COG1732	Glycine betaine
C7M29_01724	COG1174	glycine betaine transport
C7M29_01725	COG1510	regulation of RNA biosynthetic process
C7M29_01726	COG1125	glycine betaine transport
C7M29_01726	COG0517	IMP dehydrogenase activity
C7M29_01727	COG1174	glycine betaine transport
C7M29_01728	COG1732	Glycine betaine
C7M29_01729	COG1174	glycine betaine transport
C7M29_01730	COG0840	transmembrane signaling receptor activity
C7M29_01731	COG1733	regulation of RNA biosynthetic process
C7M29_01732	COG1396	sequence-specific DNA binding
C7M29_01733	COG1396	sequence-specific DNA binding
C7M29_01734	COG1476	TRANSCRIPTIONal
C7M29_01735	COG0596	Alpha beta hydrolase
C7M29_01736	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M29_01737	COG1647	Serine aminopeptidase, S33
C7M29_01738	COG0557	exoribonuclease II activity
C7M29_01739	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7M29_01741	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01742	COG1309	transcriptional regulator
C7M29_01743	COG2076	Multidrug Resistance protein
C7M29_01745	COG1289	transmembrane transporter activity
C7M29_01746	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M29_01747	COG0673	inositol 2-dehydrogenase activity
C7M29_01748	COG1937	Protein conserved in bacteria
C7M29_01749	COG2608	mercury ion transmembrane transporter activity
C7M29_01750	COG2217	Heavy metal translocating P-type atpase
C7M29_01751	COG2217	Heavy metal translocating P-type atpase
C7M29_01752	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7M29_01753	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M29_01754	COG2860	membrane
C7M29_01756	COG3973	AAA domain
C7M29_01757	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M29_01758	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M29_01759	COG0025	NhaP-type Na H and K H
C7M29_01761	COG0656	L-ascorbic acid biosynthetic process
C7M29_01762	COG4149	molybdate abc transporter
C7M29_01763	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7M29_01764	COG1910	domain protein
C7M29_01765	COG1368	sulfuric ester hydrolase activity
C7M29_01766	COG1988	membrane-bound metal-dependent
C7M29_01768	COG0531	amino acid
C7M29_01769	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M29_01770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M29_01771	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M29_01772	COG1120	ATPase activity
C7M29_01773	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M29_01774	COG1136	(ABC) transporter
C7M29_01775	COG0577	efflux transmembrane transporter activity
C7M29_01777	COG2140	Oxalate decarboxylase
C7M29_01779	COG1191	sigma factor activity
C7M29_01781	COG0745	RESPONSE REGULATOR receiver
C7M29_01782	COG2205	protein histidine kinase activity
C7M29_01783	COG3386	PFAM SMP-30 Gluconolaconase
C7M29_01784	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M29_01786	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M29_01787	COG1120	ATPase activity
C7M29_01788	COG2096	Adenosyltransferase
C7M29_01789	COG2814	Major facilitator Superfamily
C7M29_01790	COG4758	membrane
C7M29_01791	COG1842	Phage shock protein A
C7M29_01792	COG3595	metallopeptidase activity
C7M29_01793	COG4758	membrane
C7M29_01794	COG4585	Histidine kinase
C7M29_01795	COG2197	response regulator
C7M29_01797	COG0814	amino acid
C7M29_01798	COG0697	spore germination
C7M29_01800	COG0114	fumarate hydratase activity
C7M29_01801	COG1309	transcriptional regulator
C7M29_01802	COG2205	protein histidine kinase activity
C7M29_01802	COG2770	Histidine kinase
C7M29_01803	COG0745	RESPONSE REGULATOR receiver
C7M29_01804	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M29_01805	COG0783	Belongs to the Dps family
C7M29_01806	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01809	COG1120	ATPase activity
C7M29_01811	COG0583	DNA-binding transcription factor activity
C7M29_01812	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01813	COG1942	4-Oxalocrotonate Tautomerase
C7M29_01814	COG0477	Major facilitator Superfamily
C7M29_01815	COG1846	Transcriptional regulator
C7M29_01816	COG5577	PFAM Coat F domain
C7M29_01818	COG0506	proline dehydrogenase activity
C7M29_01820	COG1024	Enoyl-CoA hydratase
C7M29_01820	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M29_01821	COG0183	Belongs to the thiolase family
C7M29_01822	COG1960	acyl-CoA dehydrogenase activity
C7M29_01823	COG1393	Belongs to the ArsC family
C7M29_01824	COG0509	glycine decarboxylation via glycine cleavage system
C7M29_01826	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M29_01827	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M29_01829	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M29_01830	COG2011	ABC-type metal ion transport system permease component
C7M29_01831	COG1464	Belongs to the NlpA lipoprotein family
C7M29_01832	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M29_01833	COG0396	ATPase activity
C7M29_01834	COG0719	Fe-S assembly protein
C7M29_01835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M29_01836	COG0822	iron-sulfur transferase activity
C7M29_01837	COG0719	Fe-S assembly protein
C7M29_01838	COG0346	lactoylglutathione lyase activity
C7M29_01841	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M29_01842	COG0322	excinuclease ABC activity
C7M29_01843	COG2222	sugar isomerase
C7M29_01844	COG1653	transport
C7M29_01845	COG1175	transmembrane transport
C7M29_01846	COG0395	ABC-type sugar transport system, permease component
C7M29_01847	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M29_01848	COG2188	Transcriptional regulator
C7M29_01849	COG3842	ATPase activity
C7M29_01850	COG2356	endonuclease I
C7M29_01851	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M29_01852	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M29_01854	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7M29_01855	COG2068	MobA-Related Protein
C7M29_01856	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C7M29_01857	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7M29_01858	COG2080	2 iron, 2 sulfur cluster binding
C7M29_01859	COG2351	hydroxyisourate hydrolase activity
C7M29_01860	COG3648	Uricase
C7M29_01860	COG3195	allantoin biosynthetic process
C7M29_01861	COG2233	PERMEase
C7M29_01862	COG2233	PERMEase
C7M29_01863	COG2508	Transcriptional regulator
C7M29_01864	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M29_01866	COG1801	Protein of unknown function DUF72
C7M29_01867	COG0730	response to heat
C7M29_01868	COG0737	Belongs to the 5'-nucleotidase family
C7M29_01869	COG3377	Domain of unknown function (DUF1805)
C7M29_01871	COG0739	heme binding
C7M29_01872	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7M29_01874	COG4470	Protein conserved in bacteria
C7M29_01875	COG2445	Protein of unknown function DUF86
C7M29_01876	COG0647	UMP catabolic process
C7M29_01877	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M29_01878	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M29_01879	COG0460	homoserine dehydrogenase
C7M29_01880	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7M29_01881	COG0083	homoserine kinase activity
C7M29_01882	COG1506	peptidase
C7M29_01882	COG4946	Tricorn protease homolog
C7M29_01882	COG0823	Involved in the tonB-independent uptake of proteins
C7M29_01883	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7M29_01884	COG4837	Protein of unknown function (DUF1462)
C7M29_01885	COG1252	NADH dehydrogenase
C7M29_01886	COG4844	belongs to the
C7M29_01887	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M29_01888	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7M29_01889	COG0316	Belongs to the HesB IscA family
C7M29_01890	COG0456	acetyltransferase
C7M29_01891	COG2808	Putative FMN-binding domain
C7M29_01892	COG0516	GMP reductase activity
C7M29_01894	COG0492	ferredoxin-NADP+ reductase activity
C7M29_01895	COG1252	NADH dehydrogenase
C7M29_01897	COG3584	3D domain protein
C7M29_01898	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7M29_01899	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7M29_01900	COG2056	Na+-H+ antiporter family
C7M29_01901	COG1268	BioY protein
C7M29_01902	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M29_01903	COG2819	hydrolase of the alpha beta superfamily
C7M29_01904	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01905	COG1169	isochorismate synthase
C7M29_01906	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7M29_01907	COG1535	isochorismatase
C7M29_01907	COG3433	isochorismatase activity
C7M29_01908	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_01909	COG3251	PFAM MbtH domain protein
C7M29_01910	COG5634	Uncharacterized conserved protein (DUF2278)
C7M29_01911	COG0686	Belongs to the AlaDH PNT family
C7M29_01912	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M29_01912	COG2508	Transcriptional regulator
C7M29_01913	COG4842	Belongs to the WXG100 family
C7M29_01914	COG5417	Belongs to the EsaB family
C7M29_01915	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M29_01916	COG0433	COG0433 Predicted ATPase
C7M29_01916	COG1674	ftsk spoiiie
C7M29_01917	COG1511	domain protein
C7M29_01919	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01920	COG1418	mRNA catabolic process
C7M29_01923	COG0628	permease
C7M29_01926	COG5506	Protein of unknown function (DUF1694)
C7M29_01927	COG1335	isochorismatase
C7M29_01928	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M29_01929	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7M29_01932	COG0142	geranyltranstransferase activity
C7M29_01934	COG4585	Histidine kinase
C7M29_01935	COG2197	response regulator
C7M29_01936	COG2050	protein possibly involved in aromatic compounds catabolism
C7M29_01937	COG1320	monovalent cation:proton antiporter activity
C7M29_01938	COG2212	antiporter activity
C7M29_01939	COG1863	multisubunit Na H antiporter MnhE subunit
C7M29_01940	COG0651	ATP synthesis coupled electron transport
C7M29_01941	COG1006	Multisubunit Na H antiporter MnhC subunit
C7M29_01942	COG2111	Na H antiporter
C7M29_01943	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M29_01943	COG2111	Na H antiporter
C7M29_01945	COG3493	citrate carrier protein
C7M29_01950	COG4565	transcriptional regulatory protein
C7M29_01951	COG3290	protein histidine kinase activity
C7M29_01953	COG3011	Protein conserved in bacteria
C7M29_01954	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M29_01955	COG2814	Major facilitator Superfamily
C7M29_01957	COG5018	Exonuclease
C7M29_01959	COG2205	protein histidine kinase activity
C7M29_01960	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M29_01962	COG2267	carboxylic ester hydrolase activity
C7M29_01963	COG1522	sequence-specific DNA binding
C7M29_01964	COG0436	Aminotransferase
C7M29_01965	COG1098	S1 RNA binding domain
C7M29_01966	COG2155	Conserved Protein
C7M29_01967	COG1979	alcohol dehydrogenase
C7M29_01968	COG1979	alcohol dehydrogenase
C7M29_01969	COG0166	Belongs to the GPI family
C7M29_01972	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M29_01975	COG2738	Putative neutral zinc metallopeptidase
C7M29_01976	COG1253	flavin adenine dinucleotide binding
C7M29_01977	COG0366	Alpha amylase catalytic
C7M29_01978	COG0432	Pfam Uncharacterised protein family UPF0047
C7M29_01981	COG0840	transmembrane signaling receptor activity
C7M29_01982	COG0840	transmembrane signaling receptor activity
C7M29_01983	COG0840	transmembrane signaling receptor activity
C7M29_01984	COG0840	transmembrane signaling receptor activity
C7M29_01985	COG3347	Dehydrogenase
C7M29_01985	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_01986	COG1349	DNA-binding transcription factor activity
C7M29_01987	COG1070	Carbohydrate kinase
C7M29_01988	COG3254	rhamnose metabolic process
C7M29_01989	COG4806	L-rhamnose isomerase
C7M29_01990	COG0673	inositol 2-dehydrogenase activity
C7M29_01991	COG0628	permease
C7M29_01992	COG1968	undecaprenyl-diphosphatase activity
C7M29_01994	COG5553	Cysteine dioxygenase type I
C7M29_01995	COG0477	Major facilitator Superfamily
C7M29_01996	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M29_01997	COG4682	membrane
C7M29_01998	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M29_01999	COG0569	domain protein
C7M29_02001	COG1510	regulation of RNA biosynthetic process
C7M29_02002	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_02003	COG1454	alcohol dehydrogenase
C7M29_02005	COG2318	DinB family
C7M29_02006	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7M29_02007	COG2268	Band 7 protein
C7M29_02008	COG1247	-acetyltransferase
C7M29_02009	COG3859	Proton-coupled thiamine transporter YuaJ
C7M29_02034	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7M29_02035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M29_02036	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M29_02037	COG0297	glycogen (starch) synthase activity
C7M29_02038	COG0058	SHG alpha-glucan phosphorylase activity
C7M29_02039	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M29_02040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M29_02041	COG0438	transferase activity, transferring glycosyl groups
C7M29_02042	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M29_02044	COG0438	transferase activity, transferring glycosyl groups
C7M29_02045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M29_02046	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M29_02047	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M29_02048	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M29_02049	COG1169	isochorismate synthase
C7M29_02050	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7M29_02051	COG0596	Alpha beta hydrolase
C7M29_02052	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7M29_02053	COG0318	PFAM AMP-dependent synthetase and ligase
C7M29_02054	COG4948	Mandelate Racemase Muconate Lactonizing
C7M29_02055	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M29_02056	COG1121	(ABC) transporter
C7M29_02057	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M29_02057	COG1321	iron dependent repressor
C7M29_02058	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M29_02060	COG1294	oxidase, subunit
C7M29_02061	COG1271	oxidase subunit
C7M29_02062	COG0254	rRNA binding
C7M29_02063	COG0288	reversible hydration of carbon dioxide
C7M29_02064	COG1854	S-ribosylhomocysteine lyase activity
C7M29_02067	COG0783	Belongs to the Dps family
C7M29_02068	COG4824	toxin secretion phage lysis holin
C7M29_02069	COG0494	nUDIX hydrolase
C7M29_02070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M29_02071	COG1116	anion transmembrane transporter activity
C7M29_02072	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M29_02073	COG1506	peptidase
C7M29_02075	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7M29_02076	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7M29_02077	COG0367	asparagine synthase
C7M29_02078	COG1113	amino acid transport
C7M29_02079	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M29_02080	COG2267	carboxylic ester hydrolase activity
C7M29_02082	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M29_02083	COG1242	4 iron, 4 sulfur cluster binding
C7M29_02086	COG1725	Transcriptional regulator
C7M29_02087	COG1131	(ABC) transporter
C7M29_02090	COG1136	(ABC) transporter
C7M29_02091	COG0577	efflux transmembrane transporter activity
C7M29_02092	COG0745	RESPONSE REGULATOR receiver
C7M29_02093	COG2205	protein histidine kinase activity
C7M29_02094	COG1136	(ABC) transporter
C7M29_02095	COG0577	efflux transmembrane transporter activity
C7M29_02096	COG2433	Pfam Transposase IS66
C7M29_02097	COG2814	Major facilitator Superfamily
C7M29_02098	COG2202	Pas domain
C7M29_02098	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M29_02100	COG0495	leucyl-tRNA aminoacylation
C7M29_02101	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M29_02102	COG1486	melibiose metabolic process
C7M29_02103	COG0395	ABC-type sugar transport system, permease component
C7M29_02104	COG1175	transmembrane transport
C7M29_02105	COG1653	transport
C7M29_02106	COG1609	Transcriptional regulator
C7M29_02107	COG1073	alpha beta
C7M29_02109	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M29_02110	COG0156	8-amino-7-oxononanoate synthase activity
C7M29_02112	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7M29_02113	COG2124	cytochrome p450
C7M29_02114	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M29_02115	COG0395	ABC-type sugar transport system, permease component
C7M29_02116	COG1653	transport
C7M29_02117	COG2207	Transcriptional regulator
C7M29_02118	COG4209	transmembrane transport
C7M29_02119	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M29_02120	COG1653	transport
C7M29_02121	COG0673	inositol 2-dehydrogenase activity
C7M29_02122	COG5578	integral membrane protein
C7M29_02124	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M29_02125	COG2081	HI0933 family
C7M29_02126	COG2244	polysaccharide biosynthetic process
C7M29_02127	COG1187	pseudouridine synthase activity
C7M29_02128	COG1349	DNA-binding transcription factor activity
C7M29_02129	COG1131	(ABC) transporter
C7M29_02130	COG4473	ABC transporter
C7M29_02131	COG2252	PERMEase
C7M29_02132	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M29_02133	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M29_02134	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M29_02136	COG1597	lipid kinase activity
C7M29_02137	COG1523	belongs to the glycosyl hydrolase 13 family
C7M29_02138	COG0510	thiamine kinase activity
C7M29_02140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7M29_02141	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M29_02142	COG0281	malic enzyme
C7M29_02143	COG5584	Small secreted protein
C7M29_02144	COG1363	Peptidase, m42
C7M29_02146	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M29_02147	COG4848	Belongs to the UPF0354 family
C7M29_02148	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M29_02149	COG1674	ftsk spoiiie
C7M29_02150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7M29_02151	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M29_02152	COG4980	gas vesicle protein
C7M29_02153	COG3118	belongs to the thioredoxin family
C7M29_02154	COG1605	Chorismate mutase
C7M29_02154	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M29_02155	COG1609	Transcriptional regulator
C7M29_02156	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M29_02157	COG1360	Flagellar Motor Protein
C7M29_02158	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7M29_02159	COG0517	IMP dehydrogenase activity
C7M29_02160	COG0454	-acetyltransferase
C7M29_02161	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M29_02162	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M29_02164	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7M29_02165	COG2199	diguanylate cyclase activity
C7M29_02165	COG2203	Gaf domain
C7M29_02166	COG1956	GAF domain-containing protein
C7M29_02167	COG1309	transcriptional regulator
C7M29_02168	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M29_02169	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7M29_02170	COG1114	Component of the transport system for branched-chain amino acids
C7M29_02171	COG1104	cysteine desulfurase activity
C7M29_02172	COG0301	tRNA thio-modification
C7M29_02174	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M29_02175	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C7M29_02176	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M29_02177	COG0616	signal peptide processing
C7M29_02178	COG1714	RDD family
C7M29_02180	COG3874	Sporulation protein YtfJ
C7M29_02181	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7M29_02182	COG0827	DNA restriction-modification system
C7M29_02183	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M29_02184	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7M29_02185	COG0137	argininosuccinate synthase activity
C7M29_02186	COG0165	Argininosuccinate lyase
C7M29_02188	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_02189	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7M29_02190	COG0583	DNA-binding transcription factor activity
C7M29_02191	COG0454	-acetyltransferase
C7M29_02192	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M29_02193	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M29_02194	COG0765	amino acid transport
C7M29_02195	COG0765	amino acid transport
C7M29_02196	COG1126	abc transporter atp-binding protein
C7M29_02197	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M29_02198	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7M29_02199	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M29_02200	COG0196	riboflavin kinase activity
C7M29_02201	COG1473	amidohydrolase
C7M29_02202	COG0730	response to heat
C7M29_02203	COG4109	DRTGG domain
C7M29_02205	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M29_02209	COG0587	DNA-directed DNA polymerase activity
C7M29_02210	COG0281	malic enzyme
C7M29_02211	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7M29_02212	COG0825	malonyl-CoA metabolic process
C7M29_02213	COG0205	6-phosphofructokinase activity
C7M29_02214	COG0469	pyruvate kinase activity
C7M29_02215	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7M29_02216	COG0628	permease
C7M29_02217	COG2707	UPF0756 membrane protein
C7M29_02218	COG0372	Belongs to the citrate synthase family
C7M29_02219	COG0538	isocitrate dehydrogenase activity
C7M29_02220	COG0039	L-malate dehydrogenase activity
C7M29_02221	COG0745	RESPONSE REGULATOR receiver
C7M29_02222	COG5002	protein histidine kinase activity
C7M29_02223	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M29_02223	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M29_02224	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M29_02225	COG1971	Probably functions as a manganese efflux pump
C7M29_02226	COG0237	dephospho-CoA kinase activity
C7M29_02227	COG0656	L-ascorbic acid biosynthetic process
C7M29_02228	COG2814	Major facilitator Superfamily
C7M29_02229	COG1733	regulation of RNA biosynthetic process
C7M29_02230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M29_02231	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C7M29_02232	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7M29_02233	COG3611	Membrane attachment protein
C7M29_02234	COG1484	DNA-dependent DNA replication
C7M29_02235	COG0398	Pfam SNARE associated Golgi protein
C7M29_02238	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M29_02239	COG1011	Hydrolase
C7M29_02240	COG3275	phosphorelay sensor kinase activity
C7M29_02241	COG3279	Response regulator of the LytR AlgR family
C7M29_02242	COG1380	Effector of murein hydrolase LrgA
C7M29_02243	COG1346	cytolysis
C7M29_02245	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M29_02246	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7M29_02247	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7M29_02248	COG3326	Membrane
C7M29_02250	COG1363	Peptidase, m42
C7M29_02251	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M29_02252	COG2160	L-arabinose isomerase activity
C7M29_02253	COG1069	ribulokinase activity
C7M29_02254	COG0235	Class ii aldolase
C7M29_02255	COG0647	UMP catabolic process
C7M29_02256	COG0371	Dehydrogenase
C7M29_02257	COG1653	transport
C7M29_02258	COG1175	transmembrane transport
C7M29_02259	COG0395	ABC-type sugar transport system, permease component
C7M29_02260	COG3534	alpha-L-arabinofuranosidase
C7M29_02261	COG1966	Carbon starvation protein
C7M29_02262	COG0346	lactoylglutathione lyase activity
C7M29_02263	COG0247	lactate metabolic process
C7M29_02264	COG0277	FAD linked oxidase domain protein
C7M29_02265	COG3835	regulator
C7M29_02267	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M29_02268	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M29_02269	COG0072	phenylalanine-tRNA ligase activity
C7M29_02269	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M29_02270	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M29_02271	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C7M29_02272	COG1286	toxin biosynthetic process
C7M29_02273	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M29_02273	COG1796	DNA polymerase
C7M29_02274	COG1193	negative regulation of DNA recombination
C7M29_02275	COG3766	membrane
C7M29_02276	COG0318	PFAM AMP-dependent synthetase and ligase
C7M29_02277	COG1309	transcriptional regulator
C7M29_02278	COG1024	Enoyl-CoA hydratase
C7M29_02279	COG2086	electron transfer activity
C7M29_02280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M29_02281	COG3534	alpha-L-arabinofuranosidase
C7M29_02282	COG3118	belongs to the thioredoxin family
C7M29_02283	COG0322	excinuclease ABC activity
C7M29_02284	COG0527	aspartate kinase activity
C7M29_02285	COG1719	4-vinyl reductase, 4VR
C7M29_02286	COG2009	succinate dehydrogenase
C7M29_02287	COG1053	succinate dehydrogenase
C7M29_02288	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7M29_02289	COG0824	Thioesterase
C7M29_02290	COG2197	response regulator
C7M29_02291	COG1846	Transcriptional regulator
C7M29_02292	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M29_02293	COG5401	PFAM Sporulation and spore germination
C7M29_02294	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7M29_02295	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M29_02296	COG0622	Phosphoesterase
C7M29_02298	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
C7M29_02301	COG0454	-acetyltransferase
C7M29_02303	COG0028	Belongs to the TPP enzyme family
C7M29_02304	COG0440	acetolactate synthase activity
C7M29_02305	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7M29_02306	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M29_02307	COG0473	3-isopropylmalate dehydrogenase activity
C7M29_02308	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7M29_02309	COG0066	3-isopropylmalate dehydratase activity
C7M29_02310	COG1477	protein flavinylation
C7M29_02310	COG0457	Tetratricopeptide repeat
C7M29_02311	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7M29_02312	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7M29_02313	COG1067	ATP-dependent peptidase activity
C7M29_02313	COG0470	DNA polymerase III
C7M29_02314	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7M29_02315	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7M29_02317	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7M29_02318	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M29_02319	COG0181	hydroxymethylbilane synthase activity
C7M29_02320	COG1587	Uroporphyrinogen-III synthase
C7M29_02321	COG0113	porphobilinogen synthase activity
C7M29_02322	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M29_02323	COG1388	LysM domain
C7M29_02324	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M29_02326	COG0525	valine-tRNA ligase activity
C7M29_02327	COG0285	dihydrofolate synthase activity
C7M29_02328	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M29_02330	COG0424	maF-like protein
C7M29_02331	COG2003	Belongs to the UPF0758 family
C7M29_02332	COG1077	Cell shape determining protein MreB Mrl
C7M29_02334	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7M29_02335	COG0850	regulation of cytokinetic process
C7M29_02336	COG2894	cell division
C7M29_02337	COG0739	heme binding
C7M29_02338	COG1994	Peptidase M50
C7M29_02339	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7M29_02340	COG2868	ribosomal protein
C7M29_02341	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M29_02342	COG3290	protein histidine kinase activity
C7M29_02343	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7M29_02344	COG4492	Belongs to the UPF0735 family
C7M29_02345	COG0077	Prephenate dehydratase
C7M29_02346	COG1827	regulation of RNA biosynthetic process
C7M29_02347	COG1104	cysteine desulfurase activity
C7M29_02348	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7M29_02349	COG0157	Belongs to the NadC ModD family
C7M29_02350	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7M29_02351	COG1388	LysM domain
C7M29_02353	COG0217	transcriptional regulatory protein
C7M29_02354	COG1115	amino acid carrier protein
C7M29_02357	COG2112	serine threonine protein kinase
C7M29_02358	COG0673	inositol 2-dehydrogenase activity
C7M29_02359	COG2814	Major facilitator Superfamily
C7M29_02361	COG0632	four-way junction helicase activity
C7M29_02362	COG2255	four-way junction helicase activity
C7M29_02364	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7M29_02365	COG0343	queuine tRNA-ribosyltransferase activity
C7M29_02366	COG1862	Preprotein translocase
C7M29_02368	COG2323	membrane
C7M29_02369	COG2244	polysaccharide biosynthetic process
C7M29_02371	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M29_02371	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M29_02372	COG0490	domain, Protein
C7M29_02373	COG5416	Lipopolysaccharide assembly protein A domain
C7M29_02374	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M29_02374	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M29_02375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M29_02376	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M29_02377	COG1490	D-aminoacyl-tRNA deacylase activity
C7M29_02378	COG3103	Sh3 type 3 domain protein
C7M29_02378	COG4991	sh3 domain protein
C7M29_02378	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M29_02380	COG0124	histidyl-tRNA synthetase
C7M29_02381	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7M29_02382	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7M29_02383	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M29_02384	COG1959	2 iron, 2 sulfur cluster binding
C7M29_02385	COG1104	cysteine desulfurase activity
C7M29_02386	COG0482	sulfurtransferase activity
C7M29_02387	COG0457	Tetratricopeptide repeat
C7M29_02388	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M29_02389	COG3881	PFAM PRC-barrel domain
C7M29_02392	COG0765	amino acid transport
C7M29_02393	COG0765	amino acid transport
C7M29_02394	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M29_02395	COG1126	abc transporter atp-binding protein
C7M29_02396	COG0628	permease
C7M29_02397	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7M29_02398	COG4472	Bacterial protein of unknown function (DUF965)
C7M29_02399	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7M29_02400	COG3906	Belongs to the UPF0473 family
C7M29_02401	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M29_02402	COG4122	O-methyltransferase activity
C7M29_02405	COG0572	uridine kinase
C7M29_02406	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M29_02407	COG0768	penicillin binding
C7M29_02410	COG2226	methyltransferase
C7M29_02411	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7M29_02412	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M29_02413	COG0626	cystathionine gamma-synthase activity
C7M29_02415	COG2427	Protein of unknown function (DUF1641)
C7M29_02416	COG3383	formate dehydrogenase (NAD+) activity
C7M29_02417	COG5609	conserved protein (DUF2294)
C7M29_02418	COG2116	formate transmembrane transporter activity
C7M29_02421	COG2226	methyltransferase
C7M29_02422	COG1309	transcriptional regulator
C7M29_02423	COG2124	cytochrome p450
C7M29_02423	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M29_02425	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M29_02425	COG2755	lipolytic protein G-D-S-L family
C7M29_02427	COG1595	DNA-templated transcription, initiation
C7M29_02428	COG1378	Sugar-specific transcriptional regulator TrmB
C7M29_02429	COG1280	lysine exporter protein (LysE YggA)
C7M29_02430	COG1113	amino acid transport
C7M29_02431	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M29_02431	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7M29_02432	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M29_02433	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_02434	COG3715	PTS system
C7M29_02435	COG3716	PTS system mannose fructose sorbose family IID component
C7M29_02436	COG1621	beta-fructofuranosidase activity
C7M29_02437	COG0693	protein deglycase activity
C7M29_02438	COG1064	alcohol dehydrogenase
C7M29_02439	COG0789	Transcriptional regulator
C7M29_02440	COG5577	PFAM Coat F domain
C7M29_02442	COG1063	alcohol dehydrogenase
C7M29_02443	COG5577	PFAM Coat F domain
C7M29_02445	COG0346	lactoylglutathione lyase activity
C7M29_02446	COG4991	sh3 domain protein
C7M29_02447	COG4991	sh3 domain protein
C7M29_02448	COG0596	Alpha beta hydrolase
C7M29_02449	COG5566	PFAM Mor transcription activator
C7M29_02450	COG3409	Peptidoglycan-binding domain 1 protein
C7M29_02451	COG2828	Protein conserved in bacteria
C7M29_02452	COG0583	DNA-binding transcription factor activity
C7M29_02453	COG2851	Citrate transporter
C7M29_02454	COG0667	Aldo Keto reductase
C7M29_02455	COG1595	DNA-templated transcription, initiation
C7M29_02456	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7M29_02459	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M29_02460	COG2070	2-Nitropropane dioxygenase
C7M29_02462	COG2318	DinB family
C7M29_02464	COG1335	isochorismatase
C7M29_02466	COG2124	cytochrome p450
C7M29_02467	COG2732	(Barnase) inhibitor
C7M29_02468	COG1522	sequence-specific DNA binding
C7M29_02469	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C7M29_02470	COG1687	branched-chain amino acid
C7M29_02471	COG1114	Component of the transport system for branched-chain amino acids
C7M29_02472	COG0583	DNA-binding transcription factor activity
C7M29_02473	COG1942	4-Oxalocrotonate Tautomerase
C7M29_02474	COG1230	cation diffusion facilitator family transporter
C7M29_02475	COG2072	flavoprotein involved in K transport
C7M29_02476	COG0583	DNA-binding transcription factor activity
C7M29_02477	COG0697	spore germination
C7M29_02479	COG1253	flavin adenine dinucleotide binding
C7M29_02480	COG0456	acetyltransferase
C7M29_02481	COG2814	Major facilitator Superfamily
C7M29_02482	COG4978	Transcriptional regulator
C7M29_02482	COG0789	Transcriptional regulator
C7M29_02483	COG0662	Cupin 2, conserved barrel domain protein
C7M29_02484	COG1937	Protein conserved in bacteria
C7M29_02485	COG2210	Belongs to the sulfur carrier protein TusA family
C7M29_02486	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M29_02486	COG0425	Belongs to the sulfur carrier protein TusA family
C7M29_02487	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M29_02487	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M29_02488	COG0425	Belongs to the sulfur carrier protein TusA family
C7M29_02489	COG0730	response to heat
C7M29_02490	COG4124	Belongs to the glycosyl hydrolase 26 family
C7M29_02494	COG2856	Zn peptidase
C7M29_02496	COG0563	adenylate kinase activity
C7M29_02500	COG1484	DNA-dependent DNA replication
C7M29_02503	COG3677	Transposase
C7M29_02506	COG5484	DNA packaging
C7M29_02507	COG1783	phage Terminase large subunit
C7M29_02508	COG3409	Peptidoglycan-binding domain 1 protein
C7M29_02508	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M29_02511	COG5444	nuclease activity
C7M29_02513	COG0457	Tetratricopeptide repeat
C7M29_02516	COG0640	Transcriptional regulator
C7M29_02517	COG0346	lactoylglutathione lyase activity
C7M29_02518	COG0798	PFAM Bile acid sodium symporter
C7M29_02519	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M29_02521	COG0604	alcohol dehydrogenase
C7M29_02523	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M29_02525	COG3209	COG3209 Rhs family protein
C7M29_02527	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7M29_02528	COG0398	Pfam SNARE associated Golgi protein
C7M29_02529	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M29_02529	COG3409	Peptidoglycan-binding domain 1 protein
C7M29_02530	COG2755	lipolytic protein G-D-S-L family
C7M29_02532	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7M29_02533	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M29_02534	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M29_02535	COG1534	Rna-binding protein
C7M29_02536	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7M29_02537	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M29_02538	COG0799	negative regulation of ribosome biogenesis
C7M29_02539	COG2226	methyltransferase
C7M29_02540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M29_02541	COG1596	polysaccharide export
C7M29_02541	COG1555	photosystem II stabilization
C7M29_02542	COG2131	deaminase
C7M29_02543	COG0658	competence protein
C7M29_02543	COG2333	competence protein COMEC
C7M29_02545	COG1466	dna polymerase III delta subunit
C7M29_02546	COG0268	Binds directly to 16S ribosomal RNA
C7M29_02547	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7M29_02548	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M29_02550	COG0481	GTPase activity
C7M29_02551	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M29_02552	COG1420	regulation of RNA biosynthetic process
C7M29_02553	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7M29_02554	COG0443	Heat shock 70 kDa protein
C7M29_02555	COG0484	heat shock protein binding
C7M29_02556	COG2264	protein methyltransferase activity
C7M29_02557	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M29_02558	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M29_02559	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M29_02561	COG1610	YqeY-like protein
C7M29_02562	COG1030	water channel activity
C7M29_02563	COG4864	UPF0365 protein
C7M29_02566	COG0561	phosphatase activity
C7M29_02567	COG1702	phosphate starvation-inducible protein PhoH
C7M29_02569	COG1480	7TM receptor with intracellular HD hydrolase
C7M29_02570	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7M29_02571	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M29_02572	COG0295	cytidine deaminase activity
C7M29_02573	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M29_02575	COG1381	Involved in DNA repair and RecF pathway recombination
C7M29_02576	COG0752	glycyl-tRNA synthetase alpha subunit
C7M29_02577	COG0751	glycine-tRNA ligase activity
C7M29_02578	COG0517	IMP dehydrogenase activity
C7M29_02579	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7M29_02580	COG1671	Belongs to the UPF0178 family
C7M29_02581	COG0358	DNA primase activity
C7M29_02582	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M29_02583	COG2010	Cytochrome c
C7M29_02584	COG2384	SAM-dependent methyltransferase
C7M29_02585	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M29_02586	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7M29_02588	COG0513	Belongs to the DEAD box helicase family
C7M29_02589	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7M29_02591	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M29_02592	COG0735	belongs to the Fur family
C7M29_02593	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C7M29_02594	COG4709	membrane
C7M29_02595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7M29_02596	COG1388	LysM domain
C7M29_02598	COG5521	maltodextrose utilization protein MalA
C7M29_02599	COG2839	Protein conserved in bacteria
C7M29_02600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M29_02601	COG0477	Major facilitator Superfamily
C7M29_02603	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M29_02604	COG0573	inorganic phosphate transmembrane transporter activity
C7M29_02605	COG0581	inorganic phosphate transmembrane transporter activity
C7M29_02606	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M29_02607	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M29_02608	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M29_02611	COG0438	transferase activity, transferring glycosyl groups
C7M29_02613	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M29_02615	COG0457	Tetratricopeptide repeat
C7M29_02615	COG0705	Rhomboid family
C7M29_02616	COG4483	Protein conserved in bacteria
C7M29_02617	COG1940	carbohydrate kinase activity
C7M29_02618	COG1368	sulfuric ester hydrolase activity
C7M29_02619	COG2866	Carboxypeptidase
C7M29_02621	COG0011	TIGRFAM Protein of
C7M29_02623	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M29_02625	COG1393	Belongs to the ArsC family
C7M29_02627	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M29_02628	COG1253	flavin adenine dinucleotide binding
C7M29_02629	COG0598	Magnesium transport protein CorA
C7M29_02632	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M29_02633	COG1459	type II secretion system
C7M29_02634	COG4537	Required for transformation and DNA binding
C7M29_02635	COG4970	Tfp pilus assembly protein FimT
C7M29_02637	COG4940	Competence protein ComGF
C7M29_02642	COG0681	Belongs to the peptidase S26 family
C7M29_02644	COG1396	sequence-specific DNA binding
C7M29_02647	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M29_02648	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7M29_02649	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M29_02650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M29_02651	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M29_02652	COG0095	Lipoate-protein ligase
C7M29_02653	COG1321	iron dependent repressor
C7M29_02654	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M29_02656	COG3872	metal-dependent enzyme
C7M29_02658	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7M29_02659	COG0006	proline dipeptidase activity
C7M29_02660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7M29_02662	COG3854	ATPases associated with a variety of cellular activities
C7M29_02670	COG0511	ligase activity, forming carbon-carbon bonds
C7M29_02671	COG0439	Biotin carboxylase
C7M29_02672	COG1302	Protein conserved in bacteria
C7M29_02673	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M29_02674	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7M29_02675	COG1570	exodeoxyribonuclease VII activity
C7M29_02676	COG1722	exodeoxyribonuclease VII activity
C7M29_02677	COG0142	geranyltranstransferase activity
C7M29_02678	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7M29_02679	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M29_02680	COG1438	arginine binding
C7M29_02681	COG0497	DNA recombination
C7M29_02682	COG0750	zinc metalloprotease
C7M29_02683	COG0745	RESPONSE REGULATOR receiver
C7M29_02685	COG1902	pentaerythritol trinitrate reductase activity
C7M29_02687	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M29_02688	COG0584	glycerophosphoryl diester phosphodiesterase
C7M29_02689	COG0183	Belongs to the thiolase family
C7M29_02690	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M29_02691	COG1960	acyl-CoA dehydrogenase activity
C7M29_02692	COG0372	Belongs to the citrate synthase family
C7M29_02693	COG2079	MmgE PrpD family protein
C7M29_02694	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7M29_02696	COG3829	transcription factor binding
C7M29_02696	COG3290	protein histidine kinase activity
C7M29_02697	COG0280	phosphate acetyltransferase
C7M29_02698	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M29_02699	COG3426	butyrate kinase activity
C7M29_02700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M29_02701	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M29_02702	COG0022	dehydrogenase e1 component
C7M29_02703	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M29_02704	COG4978	Transcriptional regulator
C7M29_02704	COG0789	Transcriptional regulator
C7M29_02705	COG2814	Major facilitator Superfamily
C7M29_02706	COG1597	lipid kinase activity
C7M29_02708	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M29_02709	COG0765	amino acid transport
C7M29_02710	COG1126	abc transporter atp-binding protein
C7M29_02711	COG4129	membrane
C7M29_02712	COG1376	ErfK ybiS ycfS ynhG family protein
C7M29_02714	COG0346	lactoylglutathione lyase activity
C7M29_02715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M29_02716	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M29_02717	COG3361	conserved protein (COG2071)
C7M29_02718	COG0706	membrane insertase activity
C7M29_02720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M29_02721	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M29_02722	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M29_02723	COG1234	tRNA 3'-trailer cleavage
C7M29_02725	COG0596	Alpha beta hydrolase
C7M29_02726	COG1902	pentaerythritol trinitrate reductase activity
C7M29_02727	COG4187	Peptidase family M20/M25/M40
C7M29_02728	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M29_02729	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M29_02730	COG0300	oxidoreductase activity
C7M29_02731	COG3048	D-serine ammonia-lyase activity
C7M29_02732	COG1072	(Pantothenic acid kinase))
C7M29_02733	COG0346	lactoylglutathione lyase activity
C7M29_02735	COG2211	Major facilitator Superfamily
C7M29_02737	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M29_02739	COG0456	acetyltransferase
C7M29_02740	COG2329	Antibiotic biosynthesis monooxygenase
C7M29_02741	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M29_02741	COG0456	acetyltransferase
C7M29_02742	COG4918	Iron-sulphur cluster biosynthesis
C7M29_02744	COG1073	alpha beta
C7M29_02746	COG0667	Aldo Keto reductase
C7M29_02748	COG0494	nUDIX hydrolase
C7M29_02749	COG1379	DNA repair
C7M29_02750	COG1396	sequence-specific DNA binding
C7M29_02751	COG0252	asparaginase activity
C7M29_02752	COG1027	Aspartate ammonia-lyase
C7M29_02753	COG1757	Na H antiporter
C7M29_02754	COG0281	malic enzyme
C7M29_02756	COG1300	Membrane
C7M29_02757	COG0735	belongs to the Fur family
C7M29_02759	COG4974	Belongs to the 'phage' integrase family
C7M29_02760	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M29_02761	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7M29_02762	COG1686	Belongs to the peptidase S11 family
C7M29_02763	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M29_02764	COG2172	sigma factor antagonist activity
C7M29_02765	COG1191	sigma factor activity
C7M29_02769	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M29_02772	COG0697	spore germination
C7M29_02773	COG0019	diaminopimelate decarboxylase activity
C7M29_02774	COG4086	secreted protein
C7M29_02775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M29_02780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M29_02783	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
C7M29_02784	COG0681	Belongs to the peptidase S26 family
C7M29_02786	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M29_02786	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M29_02787	COG0307	riboflavin synthase, alpha
C7M29_02788	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M29_02788	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M29_02789	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7M29_02790	COG0456	acetyltransferase
C7M29_02791	COG1547	Domain of unknown function (DUF309)
C7M29_02792	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7M29_02793	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7M29_02795	COG1686	Belongs to the peptidase S11 family
C7M29_02796	COG2715	membrane protein required for spore maturation
C7M29_02797	COG0700	Nucleoside recognition
C7M29_02798	COG1187	pseudouridine synthase activity
C7M29_02799	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M29_02800	COG1333	cytochrome c biogenesis protein
C7M29_02801	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M29_02802	COG0745	RESPONSE REGULATOR receiver
C7M29_02803	COG5002	protein histidine kinase activity
C7M29_02804	COG1595	DNA-templated transcription, initiation
C7M29_02806	COG0710	3-dehydroquinate dehydratase activity
C7M29_02807	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M29_02808	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M29_02809	COG1141	Ferredoxin
C7M29_02810	COG4955	Helix-turn-helix domain
C7M29_02811	COG0514	ATP-dependent DNA helicase (RecQ)
C7M29_02812	COG1266	CAAX protease self-immunity
C7M29_02813	COG1388	LysM domain
C7M29_02815	COG1408	metallophosphoesterase
C7M29_02816	COG4862	establishment of competence for transformation
C7M29_02817	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M29_02818	COG0492	ferredoxin-NADP+ reductase activity
C7M29_02819	COG2339	peptidase activity
C7M29_02820	COG3409	Peptidoglycan-binding domain 1 protein
C7M29_02820	COG3773	Cell wall hydrolase
C7M29_02821	COG2959	enzyme of heme biosynthesis
C7M29_02822	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7M29_02824	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7M29_02825	COG0539	negative regulation of cytoplasmic translation
C7M29_02826	COG1304	FMN binding
C7M29_02831	COG1160	GTP binding
C7M29_02832	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7M29_02835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M29_02836	COG0776	regulation of translation
C7M29_02837	COG0302	gtp cyclohydrolase
C7M29_02839	COG0142	geranyltranstransferase activity
C7M29_02840	COG2226	methyltransferase
C7M29_02841	COG0142	geranyltranstransferase activity
C7M29_02842	COG0105	UTP biosynthetic process
C7M29_02843	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7M29_02844	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7M29_02845	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7M29_02846	COG4401	Chorismate mutase type I
C7M29_02847	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M29_02848	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M29_02850	COG0135	phosphoribosylanthranilate isomerase activity
C7M29_02851	COG0133	tryptophan synthase activity
C7M29_02854	COG0287	Prephenate dehydrogenase
C7M29_02855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7M29_02856	COG0457	Tetratricopeptide repeat
C7M29_02857	COG5582	Belongs to the UPF0302 family
C7M29_02859	COG0723	plastoquinol--plastocyanin reductase activity
C7M29_02860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M29_02861	COG2010	Cytochrome c
C7M29_02861	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M29_02862	COG4347	Protein of unknown function (DUF1405)
C7M29_02864	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M29_02865	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M29_02866	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7M29_02867	COG1803	Methylglyoxal synthase
C7M29_02868	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M29_02869	COG0438	transferase activity, transferring glycosyl groups
C7M29_02870	COG0617	tRNA 3'-terminal CCA addition
C7M29_02871	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C7M29_02871	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C7M29_02872	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7M29_02873	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7M29_02874	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7M29_02875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M29_02875	COG1199	ATP-dependent helicase activity
C7M29_02877	COG5353	protein conserved in bacteria
C7M29_02878	COG0436	Aminotransferase
C7M29_02879	COG0017	Asparaginyl-tRNA synthetase
C7M29_02880	COG3935	DnaD domain protein
C7M29_02881	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M29_02883	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M29_02883	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M29_02884	COG3331	DNA recombination
C7M29_02891	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M29_02892	COG2190	(PTS) system
C7M29_02893	COG1205	dead DEAH box helicase
C7M29_02893	COG1111	helicase
C7M29_02894	COG3359	exonuclease
C7M29_02895	COG4474	Belongs to the UPF0398 family
C7M29_02897	COG0116	Belongs to the methyltransferase superfamily
C7M29_02899	COG1199	ATP-dependent helicase activity
C7M29_02900	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_02901	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C7M29_02902	COG1609	Transcriptional regulator
C7M29_02903	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M29_02904	COG0800	Aldolase
C7M29_02906	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7M29_02907	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M29_02908	COG2233	PERMEase
C7M29_02909	COG3424	synthase
C7M29_02910	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7M29_02911	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M29_02914	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M29_02916	COG0328	RNA-DNA hybrid ribonuclease activity
C7M29_02917	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7M29_02918	COG0328	RNA-DNA hybrid ribonuclease activity
C7M29_02922	COG1278	Cold shock
C7M29_02923	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M29_02924	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7M29_02925	COG0386	Belongs to the glutathione peroxidase family
C7M29_02926	COG1418	mRNA catabolic process
C7M29_02927	COG1413	lyase activity
C7M29_02928	COG0129	dihydroxy-acid dehydratase activity
C7M29_02930	COG2521	methyltransferase
C7M29_02930	COG2136	Putative SAM-dependent methyltransferase
C7M29_02932	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M29_02933	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7M29_02934	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M29_02935	COG0204	Acyl-transferase
C7M29_02936	COG1272	protein, Hemolysin III
C7M29_02937	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M29_02938	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M29_02940	COG1999	signal sequence binding
C7M29_02941	COG2755	lipolytic protein G-D-S-L family
C7M29_02942	COG4698	Protein conserved in bacteria
C7M29_02944	COG0534	Mate efflux family protein
C7M29_02945	COG1846	Transcriptional regulator
C7M29_02946	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M29_02947	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M29_02948	COG1086	Polysaccharide biosynthesis protein
C7M29_02949	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
C7M29_02950	COG4641	Protein conserved in bacteria
C7M29_02953	COG0463	Glycosyl transferase, family 2
C7M29_02954	COG0456	acetyltransferase
C7M29_02957	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M29_02958	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M29_02959	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M29_02960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M29_02961	COG0456	acetyltransferase
C7M29_02962	COG1509	lysine 2,3-aminomutase activity
C7M29_02964	COG4479	Belongs to the UPF0346 family
C7M29_02968	COG0671	phosphoesterase, PA-phosphatase related
C7M29_02971	COG0813	purine-nucleoside phosphorylase activity
C7M29_02972	COG1876	peptidase activity
C7M29_02974	COG2226	methyltransferase
C7M29_02975	COG3409	Peptidoglycan-binding domain 1 protein
C7M29_02975	COG0793	Belongs to the peptidase S41A family
C7M29_02976	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M29_02978	COG0346	lactoylglutathione lyase activity
C7M29_02979	COG0400	carboxylic ester hydrolase activity
C7M29_02980	COG0778	Nitroreductase
C7M29_02981	COG1733	regulation of RNA biosynthetic process
C7M29_02982	COG1942	4-Oxalocrotonate Tautomerase
C7M29_02983	COG2610	gluconate transmembrane transporter activity
C7M29_02986	COG2962	Rard protein
C7M29_02988	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M29_02989	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M29_02990	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M29_02991	COG0534	Mate efflux family protein
C7M29_02993	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M29_02994	COG1819	glycosyl
C7M29_02995	COG1388	LysM domain
C7M29_02995	COG0791	NLP P60 protein
C7M29_02996	COG2032	superoxide dismutase activity
C7M29_02997	COG0714	Associated with various cellular activities
C7M29_02998	COG4548	von Willebrand factor, type A
C7M29_02999	COG0567	Dehydrogenase, E1 component
C7M29_03000	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M29_03001	COG0385	Bile acid
C7M29_03002	COG0733	neurotransmitter:sodium symporter activity
C7M29_03003	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M29_03004	COG1657	PFAM Prenyltransferase squalene oxidase
C7M29_03005	COG1012	belongs to the aldehyde dehydrogenase family
C7M29_03010	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M29_03013	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M29_03014	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M29_03015	COG0514	ATP-dependent DNA helicase (RecQ)
C7M29_03016	COG1388	LysM domain
C7M29_03016	COG3584	3D domain protein
C7M29_03017	COG2197	response regulator
C7M29_03018	COG4585	Histidine kinase
C7M29_03019	COG3239	Fatty acid desaturase
C7M29_03020	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M29_03023	COG2322	membrane
C7M29_03024	COG0741	lytic transglycosylase activity
C7M29_03025	COG0640	Transcriptional regulator
C7M29_03027	COG2378	regulation of single-species biofilm formation
C7M29_03028	COG3708	Transcriptional regulator
C7M29_03029	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M29_03030	COG1309	transcriptional regulator
C7M29_03031	COG0456	acetyltransferase
C7M29_03032	COG0662	Cupin 2, conserved barrel domain protein
C7M29_03032	COG2207	Transcriptional regulator
C7M29_03033	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M29_03034	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M29_03035	COG1231	oxidoreductase activity
C7M29_03036	COG4282	regulation of fungal-type cell wall biogenesis
C7M29_03037	COG5444	nuclease activity
C7M29_03040	COG0457	Tetratricopeptide repeat
C7M29_03043	COG0756	dUTP diphosphatase activity
C7M29_03045	COG1793	dna ligase
C7M29_03047	COG0653	protein targeting
C7M29_03050	COG3655	Transcriptional regulator
C7M29_03058	COG1396	sequence-specific DNA binding
C7M29_03059	COG2314	TM2 domain
C7M29_03060	COG0726	polysaccharide deacetylase
C7M29_03061	COG0574	Belongs to the PEP-utilizing enzyme family
C7M29_03061	COG3848	Pyruvate phosphate dikinase
C7M29_03065	COG2367	Beta-lactamase
C7M29_03066	COG0693	protein deglycase activity
C7M29_03068	COG0697	spore germination
C7M29_03069	COG0583	DNA-binding transcription factor activity
C7M29_03070	COG3739	integral membrane protein
C7M29_03071	COG3655	Transcriptional regulator
C7M29_03073	COG2720	vancomycin resistance protein
C7M29_03077	COG0456	acetyltransferase
C7M29_03079	COG2140	Oxalate decarboxylase
C7M29_03081	COG2135	peptidase activity
C7M29_03082	COG3866	Pectate lyase
C7M29_03083	COG3619	membrane
C7M29_03084	COG4305	rare lipoprotein A
C7M29_03085	COG2368	4-hydroxyphenylacetate
C7M29_03086	COG5278	phosphoserine phosphatase activity
C7M29_03086	COG0840	transmembrane signaling receptor activity
C7M29_03091	COG0243	molybdopterin cofactor binding
C7M29_03092	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M29_03093	COG1070	Carbohydrate kinase
C7M29_03094	COG2814	Major facilitator Superfamily
C7M29_03097	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M29_03100	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M29_03101	COG0300	oxidoreductase activity
C7M29_03103	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M29_03104	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M29_03105	COG0583	DNA-binding transcription factor activity
C7M29_03106	COG0067	glutamate synthase
C7M29_03106	COG0069	glutamate synthase activity
C7M29_03106	COG0070	glutamate synthase
C7M29_03107	COG0493	'glutamate synthase
C7M29_03108	COG0604	alcohol dehydrogenase
C7M29_03109	COG0583	DNA-binding transcription factor activity
C7M29_03110	COG0405	Gamma-glutamyltransferase
C7M29_03111	COG0166	Belongs to the GPI family
C7M29_03112	COG0582	viral genome integration into host DNA
C7M29_03115	COG0534	Mate efflux family protein
C7M29_03116	COG2017	converts alpha-aldose to the beta-anomer
C7M29_03117	COG2027	D-alanyl-D-alanine carboxypeptidase
C7M29_03118	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_03119	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_03120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_03121	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_03122	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_03122	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M29_03124	COG1649	PFAM Uncharacterised BCR, COG1649
C7M29_03127	COG1960	acyl-CoA dehydrogenase activity
C7M29_03128	COG0318	PFAM AMP-dependent synthetase and ligase
C7M29_03129	COG0439	Biotin carboxylase
C7M29_03130	COG0511	ligase activity, forming carbon-carbon bonds
C7M29_03131	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M29_03132	COG1024	Enoyl-CoA hydratase
C7M29_03133	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M29_03134	COG2404	hydrolase activity, acting on ester bonds
C7M29_03135	COG0586	Pfam SNARE associated Golgi protein
C7M29_03136	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M29_03137	COG2246	polysaccharide biosynthetic process
C7M29_03138	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M29_03139	COG5520	Belongs to the glycosyl hydrolase 30 family
C7M29_03141	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7M29_03142	COG1115	amino acid carrier protein
C7M29_03143	COG1115	amino acid carrier protein
C7M29_03146	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M29_03147	COG0187	DNA topoisomerase II activity
C7M29_03148	COG1832	CoA-binding protein
C7M29_03149	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7M29_03150	COG4841	protein insertion into membrane
C7M29_03152	COG0824	Thioesterase
C7M29_03156	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M29_03157	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7M29_03160	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M29_03162	COG4846	Membrane protein involved in cytochrome C biogenesis
C7M29_03163	COG2201	protein-glutamate methylesterase activity
C7M29_03164	COG0785	Cytochrome C biogenesis protein
C7M29_03166	COG3763	UPF0154 protein
C7M29_03168	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M29_03169	COG4224	UPF0291 protein
C7M29_03170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M29_03171	COG1388	LysM domain
C7M29_03172	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7M29_03173	COG0346	lactoylglutathione lyase activity
C7M29_03175	COG4195	phage-related replication protein
C7M29_03181	COG0531	amino acid
C7M29_03182	COG0697	spore germination
C7M29_03185	COG3832	glyoxalase III activity
C7M29_03187	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M29_03196	COG0756	dUTP diphosphatase activity
C7M29_03198	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M29_03199	COG2814	Major facilitator Superfamily
C7M29_03200	COG1525	nuclease
C7M29_03201	COG1070	Carbohydrate kinase
C7M29_03202	COG2115	Belongs to the xylose isomerase family
C7M29_03203	COG1940	carbohydrate kinase activity
C7M29_03204	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M29_03205	COG2211	Major facilitator Superfamily
C7M29_03206	COG0135	phosphoribosylanthranilate isomerase activity
C7M29_03210	COG3655	Transcriptional regulator
C7M29_03214	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M29_03217	COG0463	Glycosyl transferase, family 2
C7M29_03223	COG0174	glutamine synthetase
C7M29_03224	COG0789	Transcriptional regulator
C7M29_03225	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7M29_03226	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M29_03227	COG0464	growth
C7M29_03228	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M29_03229	COG4112	unkown
C7M29_03230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M29_03231	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M29_03232	COG1780	Probably involved in ribonucleotide reductase function
C7M29_03235	COG1923	regulation of RNA biosynthetic process
C7M29_03236	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7M29_03239	COG2076	Multidrug Resistance protein
C7M29_03240	COG2076	Multidrug Resistance protein
C7M29_03241	COG1764	response to oxidative stress
C7M29_03242	COG4195	phage-related replication protein
C7M29_03244	COG1404	Belongs to the peptidase S8 family
C7M29_03245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M29_03247	COG2124	cytochrome p450
C7M29_03248	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M29_03248	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M29_03248	COG3321	synthase
C7M29_03248	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7M29_03249	COG4221	oxidoreductase activity
C7M29_03249	COG3321	synthase
C7M29_03249	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_03249	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_03250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_03250	COG3321	synthase
C7M29_03250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M29_03250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M29_03250	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_03251	COG3321	synthase
C7M29_03251	COG4221	oxidoreductase activity
C7M29_03251	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M29_03251	COG0300	oxidoreductase activity
C7M29_03252	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_03252	COG3321	synthase
C7M29_03252	COG0300	oxidoreductase activity
C7M29_03252	COG0318	PFAM AMP-dependent synthetase and ligase
C7M29_03252	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M29_03253	COG1024	Enoyl-CoA hydratase
C7M29_03254	COG1024	Enoyl-CoA hydratase
C7M29_03255	COG3425	synthase
C7M29_03256	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M29_03257	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M29_03258	COG2070	2-Nitropropane dioxygenase
C7M29_03258	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M29_03259	COG3321	synthase
C7M29_03261	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M29_03262	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M29_03263	COG3226	Transcriptional regulator
C7M29_03266	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7M29_03267	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M29_03269	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7M29_03270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M29_03271	COG0156	8-amino-7-oxononanoate synthase activity
C7M29_03272	COG1063	alcohol dehydrogenase
C7M29_03273	COG2359	stage V sporulation protein S
C7M29_03274	COG1692	metallophosphoesterase
C7M29_03275	COG1418	mRNA catabolic process
C7M29_03276	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M29_03277	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7M29_03278	COG1058	Belongs to the CinA family
C7M29_03278	COG1546	Belongs to the CinA family
C7M29_03279	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M29_03280	COG1426	Protein conserved in bacteria
C7M29_03283	COG0300	oxidoreductase activity
C7M29_03284	COG0612	Peptidase, M16
C7M29_03285	COG0612	Peptidase, M16
C7M29_03286	COG2814	Major facilitator Superfamily
C7M29_03287	COG2188	Transcriptional regulator
C7M29_03288	COG1674	ftsk spoiiie
C7M29_03288	COG4980	gas vesicle protein
C7M29_03290	COG0740	serine-type endopeptidase activity
C7M29_03291	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M29_03292	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M29_03293	COG0527	aspartate kinase activity
C7M29_03294	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M29_03295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M29_03296	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M29_03297	COG1873	PFAM PRC-barrel domain
C7M29_03298	COG0612	Peptidase, M16
C7M29_03299	COG0726	polysaccharide deacetylase
C7M29_03300	COG1185	polyribonucleotide nucleotidyltransferase activity
C7M29_03301	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7M29_03302	COG0196	riboflavin kinase activity
C7M29_03303	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7M29_03304	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7M29_03305	COG1550	Protein conserved in bacteria
C7M29_03306	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7M29_03307	COG1358	cellular component organization or biogenesis
C7M29_03308	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M29_03309	COG0195	Participates in both transcription termination and antitermination
C7M29_03310	COG0779	Required for maturation of 30S ribosomal subunits
C7M29_03311	COG2176	DNA-directed DNA polymerase activity
C7M29_03312	COG0442	prolyl-tRNA aminoacylation
C7M29_03313	COG0750	zinc metalloprotease
C7M29_03314	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7M29_03315	COG4589	Belongs to the CDS family
C7M29_03316	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M29_03317	COG0233	cytoplasmic translational termination
C7M29_03318	COG0528	UMP kinase activity
C7M29_03319	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7M29_03320	COG0052	Belongs to the universal ribosomal protein uS2 family
C7M29_03322	COG1191	sigma factor activity
C7M29_03323	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C7M29_03324	COG1776	CheC inhibitor of MCP methylation
C7M29_03325	COG0835	chemotaxis
C7M29_03326	COG2198	Histidine kinase
C7M29_03326	COG0643	Histidine kinase
C7M29_03327	COG2201	protein-glutamate methylesterase activity
C7M29_03328	COG0455	bacterial-type flagellum organization
C7M29_03329	COG1419	protein localization to endoplasmic reticulum
C7M29_03330	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M29_03331	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M29_03332	COG1684	flagellar biosynthetic protein fliR
C7M29_03333	COG1987	bacterial-type flagellum assembly
C7M29_03334	COG1338	Plays a role in the flagellum-specific transport system
C7M29_03335	COG3190	flagellar
C7M29_03336	COG2201	protein-glutamate methylesterase activity
C7M29_03337	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M29_03337	COG1776	CheC inhibitor of MCP methylation
C7M29_03338	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M29_03339	COG1580	Controls the rotational direction of flagella during chemotaxis
C7M29_03340	COG4786	Flagellar basal body rod
C7M29_03341	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7M29_03342	COG3144	bacterial-type flagellum assembly
C7M29_03343	COG3334	PFAM MgtE intracellular
C7M29_03344	COG2882	bacterial-type flagellum organization
C7M29_03345	COG1157	protein secretion by the type III secretion system
C7M29_03346	COG1317	bacterial-type flagellum organization
C7M29_03347	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M29_03348	COG1766	The M ring may be actively involved in energy transduction
C7M29_03349	COG1677	Flagellar hook-basal body complex protein FliE
C7M29_03350	COG1558	bacterial-type flagellum-dependent cell motility
C7M29_03351	COG1815	bacterial-type flagellum-dependent cell motility
C7M29_03352	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M29_03353	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7M29_03354	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7M29_03355	COG4974	Belongs to the 'phage' integrase family
C7M29_03356	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7M29_03357	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M29_03358	COG0758	DNA mediated transformation
C7M29_03359	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M29_03360	COG0045	succinate-CoA ligase (ADP-forming) activity
C7M29_03361	COG2257	FlhB HrpN YscU SpaS Family
C7M29_03363	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M29_03364	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M29_03365	COG0335	large ribosomal subunit rRNA binding
C7M29_03366	COG0336	Belongs to the RNA methyltransferase TrmD family
C7M29_03367	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7M29_03369	COG1837	Belongs to the UPF0109 family
C7M29_03370	COG0228	four-way junction DNA binding
C7M29_03371	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M29_03372	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7M29_03374	COG0552	protein localization to endoplasmic reticulum
C7M29_03375	COG1196	nuclear chromosome segregation
C7M29_03376	COG0571	ribonuclease III activity
C7M29_03378	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_03379	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M29_03380	COG0416	fatty acid biosynthetic process
C7M29_03381	COG2050	protein possibly involved in aromatic compounds catabolism
C7M29_03381	COG1349	DNA-binding transcription factor activity
C7M29_03382	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M29_03383	COG1760	l-serine dehydratase
C7M29_03384	COG1760	l-serine dehydratase
C7M29_03385	COG1461	Dihydroxyacetone kinase
C7M29_03386	COG1302	Protein conserved in bacteria
C7M29_03387	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7M29_03388	COG1564	THIamine pyrophosphokinase
C7M29_03389	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M29_03390	COG1162	GTPase activity
C7M29_03391	COG2815	serine threonine protein kinase
C7M29_03391	COG0515	serine threonine protein kinase
C7M29_03392	COG0631	protein serine/threonine phosphatase activity
C7M29_03393	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7M29_03394	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M29_03394	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M29_03395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7M29_03396	COG0242	peptide deformylase activity
C7M29_03397	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M29_03398	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M29_03399	COG1758	RNA polymerase activity
C7M29_03400	COG0194	GDP metabolic process
C7M29_03402	COG1561	YicC-like family, N-terminal region
C7M29_03403	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M29_03404	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C7M29_03405	COG1648	precorrin-2 dehydrogenase activity
C7M29_03406	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7M29_03407	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M29_03408	COG0529	Catalyzes the synthesis of activated sulfate
C7M29_03409	COG2046	Belongs to the sulfate adenylyltransferase family
C7M29_03410	COG0306	phosphate transporter
C7M29_03411	COG0175	sulfate reduction
C7M29_03413	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M29_03414	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M29_03415	COG0167	dihydroorotate dehydrogenase activity
C7M29_03416	COG0543	2 iron, 2 sulfur cluster binding
C7M29_03417	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M29_03418	COG0505	Belongs to the CarA family
C7M29_03419	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M29_03420	COG0540	Belongs to the ATCase OTCase family
C7M29_03421	COG2233	PERMEase
C7M29_03422	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M29_03423	COG0564	pseudouridine synthase activity
C7M29_03424	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7M29_03425	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M29_03426	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M29_03427	COG3599	regulation of cell shape
C7M29_03428	COG2302	S4 RNA-binding domain
C7M29_03429	COG0762	integral membrane protein
C7M29_03430	COG1799	cell septum assembly
C7M29_03431	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7M29_03433	COG1873	PFAM PRC-barrel domain
C7M29_03434	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M29_03435	COG1119	ATPase activity
C7M29_03436	COG1191	sigma factor activity
C7M29_03437	COG1191	sigma factor activity
C7M29_03439	COG1404	Belongs to the peptidase S8 family
C7M29_03439	COG4412	M6 family metalloprotease domain protein
C7M29_03440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M29_03441	COG0849	cell division
C7M29_03442	COG3856	small basic protein
C7M29_03443	COG3879	Bacterial protein of unknown function (DUF881)
C7M29_03444	COG3879	Bacterial protein of unknown function (DUF881)
C7M29_03445	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M29_03446	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7M29_03447	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M29_03448	COG0772	Belongs to the SEDS family
C7M29_03449	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M29_03450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M29_03451	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7M29_03452	COG0768	penicillin binding
C7M29_03454	COG4839	cell division protein FtsL
C7M29_03455	COG0275	rRNA processing
C7M29_03456	COG2001	Belongs to the MraZ family
C7M29_03457	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C7M29_03458	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M29_03459	COG0454	-acetyltransferase
C7M29_03462	COG1399	metal-binding, possibly nucleic acid-binding protein
C7M29_03466	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M29_03467	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M29_03468	COG3314	Sporulation integral membrane protein YlbJ
C7M29_03469	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7M29_03470	COG0742	ribosomal rna small subunit methyltransferase
C7M29_03471	COG4471	UPF0298 protein
C7M29_03472	COG3679	Belongs to the UPF0342 family
C7M29_03475	COG2340	Cysteine-rich secretory protein family
C7M29_03476	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C7M29_03478	COG3336	cytochrome c oxidase
C7M29_03479	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M29_03480	COG1845	cytochrome c oxidase, subunit III
C7M29_03481	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M29_03482	COG2010	Cytochrome c
C7M29_03482	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M29_03483	COG0109	protoheme IX farnesyltransferase activity
C7M29_03484	COG1612	heme a metabolic process
C7M29_03485	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M29_03486	COG0772	Belongs to the SEDS family
C7M29_03487	COG4838	Belongs to the UPF0358 family
C7M29_03488	COG2066	Belongs to the glutaminase family
C7M29_03489	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M29_03490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7M29_03492	COG4896	Protein conserved in bacteria
C7M29_03498	COG1595	DNA-templated transcription, initiation
C7M29_03502	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7M29_03504	COG0483	inositol monophosphate 1-phosphatase activity
C7M29_03506	COG4493	Belongs to the UPF0637 family
C7M29_03507	COG4476	Belongs to the UPF0223 family
C7M29_03508	COG1982	Orn Lys Arg decarboxylase major
C7M29_03509	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M29_03510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M29_03511	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M29_03512	COG0022	dehydrogenase e1 component
C7M29_03513	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M29_03514	COG0497	DNA recombination
C7M29_03516	COG0242	peptide deformylase activity
C7M29_03517	COG0561	phosphatase activity
C7M29_03519	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M29_03520	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M29_03521	COG0569	domain protein
C7M29_03522	COG2105	PFAM AIG2 family protein
C7M29_03522	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C7M29_03523	COG3852	Histidine kinase
C7M29_03524	COG2002	toxin-antitoxin pair type II binding
C7M29_03525	COG1077	Cell shape determining protein MreB Mrl
C7M29_03527	COG2309	aminopeptidase activity
C7M29_03528	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M29_03529	COG0488	(ABC) transporter
C7M29_03531	COG0681	Belongs to the peptidase S26 family
C7M29_03532	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M29_03532	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M29_03532	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M29_03533	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M29_03534	COG1349	DNA-binding transcription factor activity
C7M29_03535	COG0577	efflux transmembrane transporter activity
C7M29_03536	COG1136	(ABC) transporter
C7M29_03537	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M29_03539	COG1132	(ABC) transporter
C7M29_03540	COG1132	(ABC) transporter
C7M29_03541	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7M29_03542	COG0314	molybdopterin synthase activity
C7M29_03543	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M29_03544	COG0303	'Molybdopterin
C7M29_03545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M29_03546	COG0746	molybdenum cofactor guanylyltransferase activity
C7M29_03549	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M29_03550	COG0450	alkyl hydroperoxide reductase
C7M29_03551	COG0668	transmembrane transport
C7M29_03553	COG1473	amidohydrolase
C7M29_03554	COG2171	N-acyltransferase activity
C7M29_03555	COG0716	FMN binding
C7M29_03557	COG0716	FMN binding
C7M29_03558	COG0583	DNA-binding transcription factor activity
C7M29_03559	COG0517	IMP dehydrogenase activity
C7M29_03561	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C7M29_03562	COG4703	Protein of unknown function (DUF1797)
C7M29_03563	COG2200	EAL domain
C7M29_03565	COG3409	Peptidoglycan-binding domain 1 protein
C7M29_03566	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_03567	COG1408	metallophosphoesterase
C7M29_03568	COG1376	ErfK ybiS ycfS ynhG family protein
C7M29_03569	COG2814	Major facilitator Superfamily
C7M29_03571	COG0784	Response regulator, receiver
C7M29_03571	COG0835	chemotaxis
C7M29_03573	COG0436	Aminotransferase
C7M29_03574	COG4191	Histidine kinase
C7M29_03575	COG0768	penicillin binding
C7M29_03576	COG2340	Cysteine-rich secretory protein family
C7M29_03577	COG4257	antibiotic catabolic process
C7M29_03578	COG2084	Dehydrogenase
C7M29_03579	COG0840	transmembrane signaling receptor activity
C7M29_03580	COG0456	acetyltransferase
C7M29_03581	COG1533	DNA photolyase activity
C7M29_03583	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M29_03584	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M29_03585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M29_03585	COG2190	(PTS) system
C7M29_03585	COG1263	PTS System
C7M29_03586	COG3711	transcriptional antiterminator
C7M29_03587	COG1609	Transcriptional regulator
C7M29_03588	COG0006	proline dipeptidase activity
C7M29_03590	COG2217	Heavy metal translocating P-type atpase
C7M29_03591	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M29_03592	COG2244	polysaccharide biosynthetic process
C7M29_03593	COG3773	Cell wall hydrolase
C7M29_03595	COG4873	Protein conserved in bacteria
C7M29_03597	COG3858	chitin binding
C7M29_03598	COG1388	LysM domain
C7M29_03599	COG4641	Protein conserved in bacteria
C7M29_03599	COG1388	LysM domain
C7M29_03600	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_03601	COG1733	regulation of RNA biosynthetic process
C7M29_03602	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7M29_03603	COG0602	queuosine metabolic process
C7M29_03604	COG0720	synthase
C7M29_03605	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7M29_03606	COG3949	Membrane
C7M29_03607	COG0542	response to heat
C7M29_03608	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M29_03609	COG1360	Flagellar Motor Protein
C7M29_03610	COG1846	Transcriptional regulator
C7M29_03611	COG3852	Histidine kinase
C7M29_03614	COG3339	Conserved Protein
C7M29_03615	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C7M29_03616	COG0235	Class ii aldolase
C7M29_03617	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
C7M29_03618	COG1850	ribulose-bisphosphate carboxylase activity
C7M29_03619	COG0436	Aminotransferase
C7M29_03620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M29_03621	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
C7M29_03622	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C7M29_03624	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M29_03625	COG5002	protein histidine kinase activity
C7M29_03626	COG3594	Acyltransferase
C7M29_03629	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M29_03630	COG0501	Belongs to the peptidase M48B family
C7M29_03634	COG1191	sigma factor activity
C7M29_03635	COG0861	Integral membrane protein TerC family
C7M29_03636	COG0586	Pfam SNARE associated Golgi protein
C7M29_03637	COG5001	Diguanylate cyclase
C7M29_03637	COG3300	MHYT domain
C7M29_03638	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C7M29_03639	COG3285	dna ligase
C7M29_03639	COG1793	dna ligase
C7M29_03640	COG0463	Glycosyl transferase, family 2
C7M29_03642	COG1408	metallophosphoesterase
C7M29_03643	COG0726	polysaccharide deacetylase
C7M29_03644	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M29_03645	COG1846	Transcriptional regulator
C7M29_03648	COG0789	Transcriptional regulator
C7M29_03649	COG2239	Acts as a magnesium transporter
C7M29_03652	COG3212	peptidase
C7M29_03653	COG3212	peptidase
C7M29_03654	COG3850	Histidine kinase
C7M29_03654	COG5002	protein histidine kinase activity
C7M29_03655	COG0745	RESPONSE REGULATOR receiver
C7M29_03657	COG4721	ABC-type cobalt transport system, permease component
C7M29_03658	COG1122	ATPase activity
C7M29_03659	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M29_03660	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M29_03661	COG1404	Belongs to the peptidase S8 family
C7M29_03662	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M29_03663	COG0590	tRNA wobble adenosine to inosine editing
C7M29_03664	COG1764	response to oxidative stress
C7M29_03665	COG1846	Transcriptional regulator
C7M29_03666	COG1764	response to oxidative stress
C7M29_03667	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M29_03668	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M29_03669	COG0788	formyltetrahydrofolate deformylase activity
C7M29_03670	COG2076	Multidrug Resistance protein
C7M29_03671	COG2076	Multidrug Resistance protein
C7M29_03672	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M29_03673	COG2318	DinB family
C7M29_03674	COG2323	membrane
C7M29_03676	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M29_03676	COG1017	nitric oxide dioxygenase activity
C7M29_03677	COG1607	acyl-coa hydrolase
C7M29_03678	COG1834	amidinotransferase
C7M29_03679	COG2706	6-phosphogluconolactonase activity
C7M29_03680	COG4608	Belongs to the ABC transporter superfamily
C7M29_03681	COG0791	NLP P60 protein
C7M29_03682	COG4948	Mandelate Racemase Muconate Lactonizing
C7M29_03683	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M29_03684	COG4166	transmembrane transport
C7M29_03685	COG0444	Belongs to the ABC transporter superfamily
C7M29_03686	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M29_03687	COG0601	transmembrane transport
C7M29_03688	COG2362	D-Aminopeptidase
C7M29_03689	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M29_03690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M29_03692	COG0463	Glycosyl transferase, family 2
C7M29_03693	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M29_03694	COG0346	lactoylglutathione lyase activity
C7M29_03695	COG0531	amino acid
C7M29_03696	COG1392	Phosphate transport regulator
C7M29_03697	COG0306	phosphate transporter
C7M29_03701	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M29_03701	COG3409	Peptidoglycan-binding domain 1 protein
C7M29_03709	COG3778	Protein conserved in bacteria
C7M29_03710	COG3299	homolog of phage Mu protein gp47
C7M29_03711	COG3628	GPW Gp25 family protein
C7M29_03713	COG4193	domain, Protein
C7M29_03714	COG1652	LysM domain
C7M29_03715	COG3953	SLT domain
C7M29_03715	COG5412	phage tail tape measure protein
C7M29_03723	COG4653	Phage capsid family
C7M29_03724	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M29_03725	COG5518	Phage portal protein
C7M29_03726	COG1783	phage Terminase large subunit
C7M29_03727	COG3728	DNA packaging
C7M29_03727	COG5484	DNA packaging
C7M29_03728	COG1595	DNA-templated transcription, initiation
C7M29_03732	COG1484	DNA-dependent DNA replication
C7M29_03733	COG1522	sequence-specific DNA binding
C7M29_03735	COG1396	sequence-specific DNA binding
C7M29_03736	COG2856	Zn peptidase
C7M29_03737	COG3546	catalase activity
C7M29_03738	COG4195	phage-related replication protein
C7M29_03740	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M29_03740	COG3409	Peptidoglycan-binding domain 1 protein
C7M29_03740	COG1388	LysM domain
C7M29_03741	COG2350	Protein conserved in bacteria
C7M29_03743	COG0457	Tetratricopeptide repeat
C7M29_03744	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M29_03745	COG2318	DinB family
C7M29_03746	COG0730	response to heat
C7M29_03747	COG2721	sulfolactate sulfo-lyase activity
C7M29_03748	COG0246	Mannitol dehydrogenase
C7M29_03749	COG1609	Transcriptional regulator
C7M29_03750	COG2271	Major facilitator Superfamily
C7M29_03751	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_03752	COG1312	Catalyzes the dehydration of D-mannonate
C7M29_03753	COG1063	alcohol dehydrogenase
C7M29_03754	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M29_03755	COG2211	Major facilitator Superfamily
C7M29_03756	COG1904	glucuronate isomerase
C7M29_03757	COG1252	NADH dehydrogenase
C7M29_03759	COG4297	protein containing double-stranded beta helix domain
C7M29_03760	COG0697	spore germination
C7M29_03761	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M29_03762	COG0390	transport system, permease component
C7M29_03763	COG1587	Uroporphyrinogen-III synthase
C7M29_03765	COG1819	glycosyl
C7M29_03766	COG2124	cytochrome p450
C7M29_03768	COG1051	belongs to the nudix hydrolase family
C7M29_03770	COG2427	Protein of unknown function (DUF1641)
C7M29_03771	COG3383	formate dehydrogenase (NAD+) activity
C7M29_03773	COG2205	protein histidine kinase activity
C7M29_03774	COG5504	Zn-dependent protease
C7M29_03777	COG0726	polysaccharide deacetylase
C7M29_03779	COG0109	protoheme IX farnesyltransferase activity
C7M29_03782	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M29_03784	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M29_03786	COG1482	cell wall glycoprotein biosynthetic process
C7M29_03787	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M29_03787	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M29_03787	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M29_03788	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M29_03788	COG3711	transcriptional antiterminator
C7M29_03790	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_03791	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M29_03792	COG5484	DNA packaging
C7M29_03795	COG3677	Transposase
C7M29_03803	COG5505	Protein of unknown function (DUF819)
C7M29_03804	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M29_03805	COG0626	cystathionine gamma-synthase activity
C7M29_03806	COG0626	cystathionine gamma-synthase activity
C7M29_03807	COG2382	esterase
C7M29_03808	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M29_03809	COG2153	protein acetylation
C7M29_03811	COG0210	DNA helicase
C7M29_03822	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M29_03823	COG0351	phosphomethylpyrimidine kinase
C7M29_03824	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M29_03825	COG2022	thiamine diphosphate biosynthetic process
C7M29_03826	COG2104	thiamine diphosphate biosynthetic process
C7M29_03827	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M29_03828	COG0352	thiamine-phosphate diphosphorylase activity
C7M29_03829	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7M29_03830	COG0569	domain protein
C7M29_03830	COG0475	glutathione-regulated potassium exporter activity
C7M29_03831	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7M29_03832	COG0564	pseudouridine synthase activity
C7M29_03833	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M29_03834	COG2357	RelA SpoT domain protein
C7M29_03836	COG4116	CYTH
C7M29_03837	COG0741	lytic transglycosylase activity
C7M29_03838	COG2346	COG2346, Truncated hemoglobins
C7M29_03842	COG1164	Oligoendopeptidase f
C7M29_03843	COG4469	Competence protein
C7M29_03844	COG4862	establishment of competence for transformation
C7M29_03845	COG0861	Integral membrane protein TerC family
C7M29_03846	COG1393	Belongs to the ArsC family
C7M29_03847	COG0456	acetyltransferase
C7M29_03848	COG2814	Major facilitator Superfamily
C7M29_03849	COG4608	Belongs to the ABC transporter superfamily
C7M29_03850	COG0444	Belongs to the ABC transporter superfamily
C7M29_03851	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M29_03852	COG0601	transmembrane transport
C7M29_03853	COG4166	transmembrane transport
C7M29_03854	COG0180	Tryptophanyl-tRNA synthetase
C7M29_03856	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M29_03857	COG0601	transmembrane transport
C7M29_03859	COG4608	Belongs to the ABC transporter superfamily
C7M29_03860	COG0444	Belongs to the ABC transporter superfamily
C7M29_03861	COG5504	Zn-dependent protease
C7M29_03862	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M29_03863	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M29_03866	COG1744	ABC transporter substrate-binding protein PnrA-like
C7M29_03868	COG2267	carboxylic ester hydrolase activity
C7M29_03871	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M29_03872	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M29_03873	COG0505	Belongs to the CarA family
C7M29_03874	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M29_03876	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7M29_03877	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7M29_03878	COG2271	Major facilitator Superfamily
C7M29_03879	COG0277	FAD linked oxidase domain protein
C7M29_03881	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M29_03882	COG1073	alpha beta
C7M29_03883	COG0561	phosphatase activity
C7M29_03887	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M29_03888	COG1307	EDD domain protein, DegV family
C7M29_03889	COG3227	Zinc metalloprotease (Elastase)
C7M29_03892	COG1695	Transcriptional regulator
C7M29_03896	COG2996	Protein conserved in bacteria
C7M29_03897	COG1666	GTP binding
C7M29_03898	COG0646	methionine synthase
C7M29_03898	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M29_03899	COG2153	protein acetylation
C7M29_03900	COG0454	-acetyltransferase
C7M29_03901	COG0454	-acetyltransferase
C7M29_03902	COG2814	Major facilitator Superfamily
C7M29_03903	COG4948	Mandelate Racemase Muconate Lactonizing
C7M29_03904	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M29_03905	COG1809	phosphosulfolactate synthase activity
C7M29_03906	COG2045	Belongs to the ComB family
C7M29_03907	COG0175	sulfate reduction
C7M29_03908	COG2046	Belongs to the sulfate adenylyltransferase family
C7M29_03909	COG0529	Catalyzes the synthesis of activated sulfate
C7M29_03910	COG2267	carboxylic ester hydrolase activity
C7M29_03911	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M29_03912	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M29_03913	COG1279	arginine transmembrane transporter activity
C7M29_03914	COG2318	DinB family
C7M29_03915	COG0673	inositol 2-dehydrogenase activity
C7M29_03916	COG1609	Transcriptional regulator
C7M29_03917	COG2207	Transcriptional regulator
C7M29_03917	COG1917	Cupin 2, conserved barrel domain protein
C7M29_03918	COG0534	Mate efflux family protein
C7M29_03919	COG1562	ergosterol biosynthetic process
C7M29_03920	COG2318	DinB family
C7M29_03921	COG0367	asparagine synthase
C7M29_03923	COG1404	Belongs to the peptidase S8 family
C7M29_03925	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7M29_03926	COG5337	Spore coat protein CotH
C7M29_03934	COG1403	HNH endonuclease
C7M29_03935	COG0419	ATPase involved in DNA repair
C7M29_03936	COG0420	3'-5' exonuclease activity
C7M29_03937	COG1074	ATP-dependent DNA helicase activity
C7M29_03938	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7M29_03939	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M29_03940	COG4533	DNA binding
C7M29_03941	COG0477	Major facilitator Superfamily
C7M29_03941	COG2814	Major facilitator Superfamily
C7M29_03942	COG3180	Ammonia monooxygenase
C7M29_03943	COG1609	Transcriptional regulator
C7M29_03944	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M29_03945	COG0561	phosphatase activity
C7M29_03946	COG0673	inositol 2-dehydrogenase activity
C7M29_03947	COG0738	Major facilitator superfamily
C7M29_03948	COG1846	Transcriptional regulator
C7M29_03949	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M29_03950	COG0681	Belongs to the peptidase S26 family
C7M29_03951	COG0398	Pfam SNARE associated Golgi protein
C7M29_03954	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M29_03956	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_03957	COG4903	ComK protein
C7M29_03959	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_03960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M29_03960	COG0723	plastoquinol--plastocyanin reductase activity
C7M29_03961	COG0840	transmembrane signaling receptor activity
C7M29_03962	COG1268	BioY protein
C7M29_03963	COG0318	PFAM AMP-dependent synthetase and ligase
C7M29_03964	COG0183	Belongs to the thiolase family
C7M29_03965	COG0406	alpha-ribazole phosphatase activity
C7M29_03966	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M29_03967	COG0604	alcohol dehydrogenase
C7M29_03968	COG0456	acetyltransferase
C7M29_03970	COG0501	Belongs to the peptidase M48B family
C7M29_03972	COG0318	PFAM AMP-dependent synthetase and ligase
C7M29_03973	COG0702	epimerase
C7M29_03974	COG0095	Lipoate-protein ligase
C7M29_03975	COG1234	tRNA 3'-trailer cleavage
C7M29_03976	COG1301	dicarboxylic acid transport
C7M29_03977	COG4405	Protein conserved in bacteria
C7M29_03978	COG1363	Peptidase, m42
C7M29_03979	COG4377	Putative membrane peptidase family (DUF2324)
C7M29_03980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M29_03981	COG1511	domain protein
C7M29_03982	COG1309	transcriptional regulator
C7M29_03985	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7M29_03986	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M29_03987	COG2329	Antibiotic biosynthesis monooxygenase
C7M29_03989	COG3069	C4-dicarboxylate transmembrane transporter activity
C7M29_03990	COG1473	amidohydrolase
C7M29_03992	COG4473	ABC transporter
C7M29_03993	COG1131	(ABC) transporter
C7M29_03994	COG0537	adenosine 5'-monophosphoramidase activity
C7M29_03995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M29_03997	COG4980	gas vesicle protein
C7M29_03998	COG1846	Transcriptional regulator
C7M29_04001	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M29_04003	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7M29_04004	COG4717	serine-type aminopeptidase activity
C7M29_04005	COG0420	3'-5' exonuclease activity
C7M29_04006	COG1668	transmembrane transport
C7M29_04007	COG4152	abc transporter atp-binding protein
C7M29_04009	COG1024	Enoyl-CoA hydratase
C7M29_04011	COG0490	domain, Protein
C7M29_04012	COG0475	glutathione-regulated potassium exporter activity
C7M29_04013	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M29_04014	COG0561	phosphatase activity
C7M29_04015	COG4335	DNA alkylation repair
C7M29_04016	COG3679	Belongs to the UPF0342 family
C7M29_04017	COG4399	Belongs to the UPF0754 family
C7M29_04018	COG0189	ligase activity
C7M29_04019	COG0189	ligase activity
C7M29_04022	COG0702	epimerase
C7M29_04023	COG1132	(ABC) transporter
C7M29_04024	COG1132	(ABC) transporter
C7M29_04025	COG0589	response to stress
C7M29_04026	COG1757	Na H antiporter
C7M29_04027	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M29_04028	COG0726	polysaccharide deacetylase
C7M29_04029	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M29_04030	COG0668	transmembrane transport
C7M29_04032	COG0584	glycerophosphoryl diester phosphodiesterase
C7M29_04033	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M29_04034	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M29_04035	COG1253	flavin adenine dinucleotide binding
C7M29_04036	COG0436	Aminotransferase
C7M29_04037	COG0789	Transcriptional regulator
C7M29_04038	COG1253	flavin adenine dinucleotide binding
C7M29_04039	COG0204	Acyl-transferase
C7M29_04040	COG0667	Aldo Keto reductase
C7M29_04041	COG1595	DNA-templated transcription, initiation
C7M29_04044	COG0456	acetyltransferase
C7M29_04045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M29_04046	COG0733	neurotransmitter:sodium symporter activity
C7M29_04047	COG0531	amino acid
C7M29_04048	COG1028	Short-chain dehydrogenase reductase Sdr
C7M29_04049	COG0372	Belongs to the citrate synthase family
C7M29_04050	COG0583	DNA-binding transcription factor activity
C7M29_04051	COG0791	NLP P60 protein
C7M29_04051	COG1388	LysM domain
C7M29_04052	COG1785	Belongs to the alkaline phosphatase family
C7M29_04053	COG2719	SpoVR family
C7M29_04054	COG0668	transmembrane transport
C7M29_04055	COG1959	2 iron, 2 sulfur cluster binding
C7M29_04056	COG1388	LysM domain
C7M29_04056	COG0791	NLP P60 protein
C7M29_04059	COG0431	NADPH-dependent FMN reductase
C7M29_04060	COG2197	response regulator
C7M29_04061	COG4585	Histidine kinase
C7M29_04061	COG2203	Gaf domain
C7M29_04062	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M29_04063	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7M29_04064	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M29_04065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M29_04066	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7M29_04067	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M29_04068	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M29_04068	COG3153	acetyltransferase
C7M29_04069	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M29_04070	COG0517	IMP dehydrogenase activity
C7M29_04072	COG0564	pseudouridine synthase activity
C7M29_04073	COG3764	Sortase (surface protein transpeptidase)
C7M29_04074	COG0737	Belongs to the 5'-nucleotidase family
C7M29_04074	COG1525	nuclease
C7M29_04074	COG4085	toxin activity
C7M29_04075	COG5577	PFAM Coat F domain
C7M29_04079	COG1823	symporter activity
C7M29_04080	COG3706	GGDEF domain
C7M29_04081	COG1464	Belongs to the NlpA lipoprotein family
C7M29_04082	COG1278	Cold shock
C7M29_04083	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M29_04084	COG1131	(ABC) transporter
C7M29_04085	COG1131	(ABC) transporter
C7M29_04086	COG1725	Transcriptional regulator