locus-tag	class	description
ETL58_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ETL58_00010	COG0592	DNA-directed DNA polymerase activity
ETL58_00015	COG2501	S4 domain
ETL58_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ETL58_00030	COG0187	DNA topoisomerase II activity
ETL58_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETL58_00070	COG0517	IMP dehydrogenase activity
ETL58_00070	COG0516	GMP reductase activity
ETL58_00075	COG1686	Belongs to the peptidase S11 family
ETL58_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ETL58_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ETL58_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ETL58_00100	COG1428	Deoxynucleoside kinase
ETL58_00105	COG1428	Deoxynucleoside kinase
ETL58_00110	COG1388	LysM domain
ETL58_00110	COG3858	chitin binding
ETL58_00115	COG1335	isochorismatase
ETL58_00120	COG0590	tRNA wobble adenosine to inosine editing
ETL58_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ETL58_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ETL58_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ETL58_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
ETL58_00190	COG3853	Toxic anion resistance protein (TelA)
ETL58_00195	COG1982	Orn Lys Arg decarboxylase major
ETL58_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ETL58_00205	COG3870	Protein conserved in bacteria
ETL58_00210	COG1728	Protein conserved in bacteria
ETL58_00215	COG0470	DNA polymerase III
ETL58_00220	COG1774	PSP1 C-terminal conserved region
ETL58_00225	COG4467	Involved in initiation control of chromosome replication
ETL58_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ETL58_00235	COG2827	Endonuclease containing a URI domain
ETL58_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ETL58_00245	COG2002	toxin-antitoxin pair type II binding
ETL58_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETL58_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETL58_00255	COG0084	hydrolase, TatD family'
ETL58_00260	COG3583	domain protein
ETL58_00260	COG3584	3D domain protein
ETL58_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ETL58_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ETL58_00280	COG4466	Protein conserved in bacteria
ETL58_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ETL58_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETL58_00300	COG0251	oxidation-reduction process
ETL58_00305	COG2088	sporulation resulting in formation of a cellular spore
ETL58_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ETL58_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ETL58_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ETL58_00325	COG0193	aminoacyl-tRNA hydrolase activity
ETL58_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETL58_00340	COG2002	toxin-antitoxin pair type II binding
ETL58_00345	COG2244	polysaccharide biosynthetic process
ETL58_00350	COG3956	TIGRFAM MazG family protein
ETL58_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ETL58_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ETL58_00375	COG1098	S1 RNA binding domain
ETL58_00390	COG2208	phosphoserine phosphatase activity
ETL58_00395	COG2304	oxidoreductase activity
ETL58_00400	COG0515	serine threonine protein kinase
ETL58_00405	COG0037	tRNA processing
ETL58_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETL58_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ETL58_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ETL58_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETL58_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETL58_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETL58_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
ETL58_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETL58_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ETL58_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ETL58_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ETL58_00470	COG1396	sequence-specific DNA binding
ETL58_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETL58_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ETL58_00560	COG4463	regulation of RNA biosynthetic process
ETL58_00565	COG3880	PFAM UvrB UvrC protein
ETL58_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ETL58_00575	COG0542	response to heat
ETL58_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ETL58_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ETL58_00590	COG4956	integral membrane protein (PIN domain superfamily)
ETL58_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ETL58_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ETL58_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ETL58_00615	COG1045	serine acetyltransferase
ETL58_00620	COG0215	cysteine-tRNA ligase activity
ETL58_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ETL58_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETL58_00635	COG3688	RNA-binding protein containing a PIN domain
ETL58_00640	COG1595	DNA-templated transcription, initiation
ETL58_00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ETL58_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ETL58_00655	COG0250	Participates in transcription elongation, termination and antitermination
ETL58_00660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ETL58_00665	COG0081	regulation of translation
ETL58_00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ETL58_00675	COG0222	ribosome binding
ETL58_00680	COG2813	Specifically methylates the guanine in position
ETL58_00685	COG0085	RNA polymerase activity
ETL58_00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ETL58_00695	COG1358	cellular component organization or biogenesis
ETL58_00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ETL58_00705	COG0049	tRNA binding
ETL58_00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETL58_00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ETL58_00720	COG0596	Alpha beta hydrolase
ETL58_00725	COG0051	transcription antitermination factor activity, RNA binding
ETL58_00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ETL58_00735	COG0088	Forms part of the polypeptide exit tunnel
ETL58_00740	COG0089	rRNA binding
ETL58_00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ETL58_00750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ETL58_00755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ETL58_00760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ETL58_00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ETL58_00770	COG0255	Belongs to the universal ribosomal protein uL29 family
ETL58_00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ETL58_00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ETL58_00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ETL58_00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ETL58_00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ETL58_00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ETL58_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ETL58_00820	COG1841	ribosomal large subunit assembly
ETL58_00825	COG0200	Binds to the 23S rRNA
ETL58_00830	COG0201	protein transport
ETL58_00835	COG0563	adenylate kinase activity
ETL58_00840	COG0024	Methionine aminopeptidase
ETL58_00845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
ETL58_00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ETL58_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ETL58_00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ETL58_00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ETL58_00870	COG0202	RNA polymerase activity
ETL58_00875	COG0203	ribosomal protein L17
ETL58_00880	COG1122	ATPase activity
ETL58_00885	COG1122	ATPase activity
ETL58_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETL58_00895	COG0101	tRNA pseudouridine synthase activity
ETL58_00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ETL58_00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ETL58_00910	COG2226	methyltransferase
ETL58_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_00925	COG0489	protein tyrosine kinase activity
ETL58_00935	COG2194	sulfuric ester hydrolase activity
ETL58_00940	COG0726	polysaccharide deacetylase
ETL58_01115	COG0659	secondary active sulfate transmembrane transporter activity
ETL58_01120	COG0385	Bile acid
ETL58_01125	COG2819	hydrolase of the alpha beta superfamily
ETL58_01130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_01135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_01140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_01145	COG2207	Transcriptional regulator
ETL58_01145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_01150	COG3876	Protein conserved in bacteria
ETL58_01155	COG1472	Belongs to the glycosyl hydrolase 3 family
ETL58_01160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETL58_01165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_01165	COG1263	PTS System
ETL58_01170	COG1737	Transcriptional regulator
ETL58_01175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ETL58_01180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_01185	COG1683	Conserved Protein
ETL58_01215	COG1595	DNA-templated transcription, initiation
ETL58_01220	COG5662	AntiSigma factor
ETL58_01225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETL58_01230	COG4856	YbbR-like protein
ETL58_01235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETL58_01240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ETL58_01250	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ETL58_01255	COG2169	Transcriptional regulator
ETL58_01260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETL58_01265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETL58_01270	COG3002	Belongs to the UPF0753 family
ETL58_01275	COG0288	reversible hydration of carbon dioxide
ETL58_01285	COG5609	conserved protein (DUF2294)
ETL58_01290	COG0640	Transcriptional regulator
ETL58_01295	COG2814	Major facilitator Superfamily
ETL58_01310	COG0596	Alpha beta hydrolase
ETL58_01315	COG0745	RESPONSE REGULATOR receiver
ETL58_01320	COG0642	Histidine kinase
ETL58_01330	COG0515	serine threonine protein kinase
ETL58_01345	COG1113	amino acid transport
ETL58_01365	COG2124	cytochrome p450
ETL58_01375	COG0531	amino acid
ETL58_01380	COG0584	glycerophosphoryl diester phosphodiesterase
ETL58_01385	COG2271	Major facilitator Superfamily
ETL58_01400	COG0456	acetyltransferase
ETL58_01400	COG1846	Transcriptional regulator
ETL58_01405	COG2271	Major facilitator Superfamily
ETL58_01415	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_01420	COG0697	spore germination
ETL58_01425	COG2207	Transcriptional regulator
ETL58_01425	COG1917	Cupin 2, conserved barrel domain protein
ETL58_01430	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ETL58_01435	COG3591	Belongs to the peptidase S1B family
ETL58_01445	COG0596	Alpha beta hydrolase
ETL58_01450	COG1183	phosphatidylcholine synthase activity
ETL58_01455	COG0586	Pfam SNARE associated Golgi protein
ETL58_01460	COG0688	phosphatidylethanolamine metabolic process
ETL58_01475	COG1301	dicarboxylic acid transport
ETL58_01480	COG2190	(PTS) system
ETL58_01480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_01480	COG1263	PTS System
ETL58_01485	COG0363	glucosamine-6-phosphate deaminase activity
ETL58_01500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETL58_01505	COG0833	amino acid
ETL58_01510	COG2040	homocysteine
ETL58_01520	COG1115	amino acid carrier protein
ETL58_01525	COG2066	Belongs to the glutaminase family
ETL58_01530	COG4191	Histidine kinase
ETL58_01535	COG0784	Response regulator, receiver
ETL58_01545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETL58_01550	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_01555	COG2271	Major facilitator Superfamily
ETL58_01560	COG4948	Mandelate Racemase Muconate Lactonizing
ETL58_01565	COG2186	Transcriptional regulator
ETL58_01570	COG2721	sulfolactate sulfo-lyase activity
ETL58_01575	COG3173	Aminoglycoside phosphotransferase
ETL58_01590	COG0745	RESPONSE REGULATOR receiver
ETL58_01595	COG2205	protein histidine kinase activity
ETL58_01600	COG1131	(ABC) transporter
ETL58_01620	COG3773	Cell wall hydrolase
ETL58_01625	COG2304	oxidoreductase activity
ETL58_01635	COG3540	Alkaline phosphatase
ETL58_01640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETL58_01645	COG0805	protein transport
ETL58_01650	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ETL58_01655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETL58_01660	COG0477	Major facilitator Superfamily
ETL58_01665	COG1309	transcriptional regulator
ETL58_01670	COG0252	asparaginase activity
ETL58_01675	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ETL58_01680	COG1714	RDD family
ETL58_01685	COG1405	negative regulation of cell septum assembly
ETL58_01685	COG3012	SEC-C Motif Domain Protein
ETL58_01690	COG3290	protein histidine kinase activity
ETL58_01695	COG3279	Response regulator of the LytR AlgR family
ETL58_01700	COG4555	ABC transporter
ETL58_01705	COG1668	transmembrane transport
ETL58_01725	COG1595	DNA-templated transcription, initiation
ETL58_01730	COG1595	DNA-templated transcription, initiation
ETL58_01735	COG1876	peptidase activity
ETL58_01740	COG0457	Tetratricopeptide repeat
ETL58_01745	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_01750	COG0366	Alpha amylase catalytic
ETL58_01755	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETL58_01760	COG1121	(ABC) transporter
ETL58_01765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETL58_01770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_01775	COG2310	stress, protein
ETL58_01780	COG2310	stress, protein
ETL58_01785	COG2310	stress, protein
ETL58_01790	COG0861	Integral membrane protein TerC family
ETL58_01800	COG3853	Toxic anion resistance protein (TelA)
ETL58_01805	COG0477	Major facilitator Superfamily
ETL58_01815	COG2814	Major facilitator Superfamily
ETL58_01820	COG0640	Transcriptional regulator
ETL58_01825	COG4175	Glycine betaine
ETL58_01825	COG0517	IMP dehydrogenase activity
ETL58_01830	COG4176	ABC-type proline glycine betaine transport system permease component
ETL58_01835	COG2113	Glycine betaine
ETL58_01840	COG1473	amidohydrolase
ETL58_01845	COG1288	antiporter activity
ETL58_01855	COG0366	Alpha amylase catalytic
ETL58_01860	COG0039	L-malate dehydrogenase activity
ETL58_01865	COG1620	l-lactate permease
ETL58_01870	COG2814	Major facilitator Superfamily
ETL58_01875	COG1846	Transcriptional regulator
ETL58_01880	COG1280	lysine exporter protein (LysE YggA)
ETL58_01885	COG3403	YqcI/YcgG family
ETL58_01890	COG1113	amino acid transport
ETL58_01895	COG3665	Urea carboxylase-associated protein
ETL58_01900	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ETL58_01905	COG1660	Displays ATPase and GTPase activities
ETL58_01910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ETL58_01915	COG2226	methyltransferase
ETL58_01920	COG0583	DNA-binding transcription factor activity
ETL58_01925	COG3458	cephalosporin-C deacetylase activity
ETL58_01930	COG3541	Predicted nucleotidyltransferase
ETL58_01935	COG0506	proline dehydrogenase activity
ETL58_01940	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_01945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETL58_01950	COG2508	Transcriptional regulator
ETL58_01955	COG3689	TIGRFAM TIGR03943 family protein
ETL58_01960	COG0701	Predicted permease
ETL58_01965	COG2267	carboxylic ester hydrolase activity
ETL58_01970	COG0492	ferredoxin-NADP+ reductase activity
ETL58_01975	COG1587	Uroporphyrinogen-III synthase
ETL58_01975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETL58_01980	COG2146	nitrite reductase [NAD(P)H] activity
ETL58_01985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETL58_01990	COG0243	molybdopterin cofactor binding
ETL58_01995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETL58_02000	COG2223	nitrite transmembrane transporter activity
ETL58_02005	COG1469	GTP cyclohydrolase I activity
ETL58_02010	COG1376	ErfK ybiS ycfS ynhG family protein
ETL58_02020	COG0523	cobalamin synthesis protein
ETL58_02025	COG0765	amino acid transport
ETL58_02030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_02040	COG1714	RDD family
ETL58_02050	COG2723	6-phospho-beta-galactosidase activity
ETL58_02060	COG3209	COG3209 Rhs family protein
ETL58_02065	COG0840	transmembrane signaling receptor activity
ETL58_02065	COG3290	protein histidine kinase activity
ETL58_02070	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ETL58_02075	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ETL58_02080	COG1733	regulation of RNA biosynthetic process
ETL58_02085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_02090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_02095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_02100	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ETL58_02105	COG2814	Major facilitator Superfamily
ETL58_02115	COG0697	spore germination
ETL58_02120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_02130	COG2364	Membrane
ETL58_02140	COG1126	abc transporter atp-binding protein
ETL58_02145	COG0765	amino acid transport
ETL58_02150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_02155	COG0583	DNA-binding transcription factor activity
ETL58_02160	COG0163	prenyltransferase activity
ETL58_02165	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ETL58_02180	COG0596	Alpha beta hydrolase
ETL58_02185	COG3104	oligopeptide transport
ETL58_02190	COG5434	Belongs to the glycosyl hydrolase 28 family
ETL58_02200	COG0697	spore germination
ETL58_02210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ETL58_02215	COG1136	(ABC) transporter
ETL58_02220	COG0577	efflux transmembrane transporter activity
ETL58_02225	COG0745	RESPONSE REGULATOR receiver
ETL58_02230	COG5002	protein histidine kinase activity
ETL58_02230	COG3850	Histidine kinase
ETL58_02235	COG0457	Tetratricopeptide repeat
ETL58_02255	COG0527	aspartate kinase activity
ETL58_02260	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_02265	COG4605	iron ion homeostasis
ETL58_02270	COG4604	ABC transporter, ATP-binding protein
ETL58_02275	COG4607	ABC-type enterochelin transport system periplasmic component
ETL58_02280	COG2814	Major facilitator Superfamily
ETL58_02285	COG1309	transcriptional regulator
ETL58_02290	COG0778	Nitroreductase
ETL58_02295	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETL58_02300	COG0640	Transcriptional regulator
ETL58_02305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_02310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ETL58_02315	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_02320	COG4975	Glucose uptake
ETL58_02325	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_02330	COG4549	nuclear export factor GLE1
ETL58_02335	COG1276	copper resistance
ETL58_02335	COG2372	response to copper ion
ETL58_02340	COG1349	DNA-binding transcription factor activity
ETL58_02350	COG2213	PTS system mannitol-specific
ETL58_02355	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_02360	COG0246	Mannitol dehydrogenase
ETL58_02365	COG0473	3-isopropylmalate dehydrogenase activity
ETL58_02370	COG0681	Belongs to the peptidase S26 family
ETL58_02375	COG0412	Dienelactone hydrolase
ETL58_02380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETL58_02390	COG0561	phosphatase activity
ETL58_02395	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ETL58_02400	COG1914	H( )-stimulated, divalent metal cation uptake system
ETL58_02405	COG4336	lyase activity
ETL58_02410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ETL58_02415	COG1984	allophanate hydrolase subunit 2
ETL58_02420	COG1414	Transcriptional regulator
ETL58_02425	COG2755	lipolytic protein G-D-S-L family
ETL58_02435	COG2329	Antibiotic biosynthesis monooxygenase
ETL58_02440	COG0768	penicillin binding
ETL58_02445	COG4989	oxidoreductase activity
ETL58_02450	COG3711	transcriptional antiterminator
ETL58_02455	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_02460	COG2226	methyltransferase
ETL58_02465	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_02470	COG1917	Cupin 2, conserved barrel domain protein
ETL58_02475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_02480	COG3871	stress protein (general stress protein 26)
ETL58_02490	COG2814	Major facilitator Superfamily
ETL58_02495	COG1522	sequence-specific DNA binding
ETL58_02500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETL58_02500	COG0551	DNA topoisomerase type I activity
ETL58_02505	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ETL58_02510	COG3706	GGDEF domain
ETL58_02515	COG5298	Protein conserved in bacteria
ETL58_02520	COG1215	transferase activity, transferring glycosyl groups
ETL58_02530	COG0531	amino acid
ETL58_02535	COG0494	nUDIX hydrolase
ETL58_02540	COG0028	Belongs to the TPP enzyme family
ETL58_02550	COG1914	H( )-stimulated, divalent metal cation uptake system
ETL58_02555	COG2261	transglycosylase associated protein
ETL58_02560	COG4876	unkown
ETL58_02565	COG2217	Heavy metal translocating P-type atpase
ETL58_02570	COG3729	General stress protein
ETL58_02575	COG0662	Cupin 2, conserved barrel domain protein
ETL58_02580	COG2329	Antibiotic biosynthesis monooxygenase
ETL58_02585	COG3546	catalase activity
ETL58_02590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ETL58_02595	COG3290	protein histidine kinase activity
ETL58_02600	COG4565	transcriptional regulatory protein
ETL58_02605	COG1301	dicarboxylic acid transport
ETL58_02610	COG0628	permease
ETL58_02615	COG1131	(ABC) transporter
ETL58_02620	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETL58_02630	COG1960	acyl-CoA dehydrogenase activity
ETL58_02645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETL58_02650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_02655	COG1181	Belongs to the D-alanine--D-alanine ligase family
ETL58_02660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETL58_02670	COG0513	Belongs to the DEAD box helicase family
ETL58_02675	COG3402	PFAM membrane-flanked domain
ETL58_02680	COG3428	Bacterial PH domain
ETL58_02685	COG0705	Rhomboid family
ETL58_02690	COG0736	holo-[acyl-carrier-protein] synthase activity
ETL58_02695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ETL58_02700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ETL58_02705	COG0864	Transcriptional regulator
ETL58_02710	COG2337	Toxic component of a toxin-antitoxin (TA) module
ETL58_02715	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_02720	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_02725	COG2172	sigma factor antagonist activity
ETL58_02730	COG2208	phosphoserine phosphatase activity
ETL58_02735	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_02740	COG2172	sigma factor antagonist activity
ETL58_02745	COG1191	sigma factor activity
ETL58_02750	COG2208	phosphoserine phosphatase activity
ETL58_02755	COG2183	response to ionizing radiation
ETL58_02765	COG3091	SprT-like family
ETL58_02815	COG0515	serine threonine protein kinase
ETL58_02825	COG0515	serine threonine protein kinase
ETL58_02830	COG1132	(ABC) transporter
ETL58_02845	COG1476	TRANSCRIPTIONal
ETL58_02855	COG3239	Fatty acid desaturase
ETL58_02860	COG1278	Cold shock
ETL58_02865	COG1329	Transcriptional regulator
ETL58_02875	COG0697	spore germination
ETL58_02880	COG2207	Transcriptional regulator
ETL58_02880	COG1917	Cupin 2, conserved barrel domain protein
ETL58_02885	COG0697	spore germination
ETL58_02890	COG3708	Transcriptional regulator
ETL58_02890	COG2207	Transcriptional regulator
ETL58_02895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_02900	COG0477	Major facilitator Superfamily
ETL58_02910	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ETL58_02925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_02930	COG1309	transcriptional regulator
ETL58_02940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_02945	COG2030	dehydratase
ETL58_02950	COG3545	Serine hydrolase
ETL58_02955	COG1733	regulation of RNA biosynthetic process
ETL58_02960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_02965	COG1733	regulation of RNA biosynthetic process
ETL58_02970	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETL58_02975	COG2814	Major facilitator Superfamily
ETL58_02980	COG1309	transcriptional regulator
ETL58_02985	COG0640	Transcriptional regulator
ETL58_02990	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ETL58_03000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_03005	COG0697	spore germination
ETL58_03010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_03015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETL58_03020	COG0640	Transcriptional regulator
ETL58_03025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ETL58_03040	COG4585	Histidine kinase
ETL58_03045	COG2197	response regulator
ETL58_03050	COG2409	Drug exporters of the RND superfamily
ETL58_03055	COG0596	Alpha beta hydrolase
ETL58_03060	COG1811	Na channel or pump
ETL58_03065	COG0789	Transcriptional regulator
ETL58_03065	COG4978	Transcriptional regulator
ETL58_03070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETL58_03075	COG0778	Nitroreductase
ETL58_03080	COG0346	lactoylglutathione lyase activity
ETL58_03085	COG2259	Doxx family
ETL58_03090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_03110	COG2323	membrane
ETL58_03115	COG2323	membrane
ETL58_03120	COG0071	Belongs to the small heat shock protein (HSP20) family
ETL58_03135	COG1309	transcriptional regulator
ETL58_03145	COG0456	acetyltransferase
ETL58_03155	COG1113	amino acid transport
ETL58_03160	COG2318	DinB family
ETL58_03165	COG1846	Transcriptional regulator
ETL58_03170	COG2409	Drug exporters of the RND superfamily
ETL58_03170	COG1033	growth of symbiont in host cell
ETL58_03175	COG0778	Nitroreductase
ETL58_03180	COG1846	Transcriptional regulator
ETL58_03185	COG2814	Major facilitator Superfamily
ETL58_03190	COG0730	response to heat
ETL58_03195	COG1802	Transcriptional regulator
ETL58_03200	COG3858	chitin binding
ETL58_03200	COG1388	LysM domain
ETL58_03205	COG1819	glycosyl
ETL58_03215	COG1785	Belongs to the alkaline phosphatase family
ETL58_03220	COG5646	InterPro IPR014922
ETL58_03230	COG0454	-acetyltransferase
ETL58_03235	COG1078	dGTPase activity
ETL58_03240	COG1388	LysM domain
ETL58_03245	COG2814	Major facilitator Superfamily
ETL58_03250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETL58_03255	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETL58_03260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETL58_03265	COG2723	6-phospho-beta-galactosidase activity
ETL58_03270	COG2188	Transcriptional regulator
ETL58_03275	COG1940	carbohydrate kinase activity
ETL58_03280	COG1482	cell wall glycoprotein biosynthetic process
ETL58_03285	COG4124	Belongs to the glycosyl hydrolase 26 family
ETL58_03330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ETL58_03335	COG0802	atpase or kinase
ETL58_03340	COG1214	PFAM Peptidase M22, glycoprotease
ETL58_03345	COG0456	acetyltransferase
ETL58_03350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ETL58_03355	COG0488	(ABC) transporter
ETL58_03360	COG0315	cyclic pyranopterin monophosphate synthase activity
ETL58_03365	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ETL58_03370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETL58_03375	COG0805	protein transport
ETL58_03390	COG1266	CAAX protease self-immunity
ETL58_03395	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETL58_03400	COG0459	protein refolding
ETL58_03405	COG4974	Belongs to the 'phage' integrase family
ETL58_03410	COG2856	Zn peptidase
ETL58_03425	COG1396	sequence-specific DNA binding
ETL58_03475	COG5377	YqaJ viral recombinase family
ETL58_03480	COG3723	Recombinational DNA repair protein, rece pathway
ETL58_03485	COG3935	DnaD domain protein
ETL58_03490	COG1484	DNA-dependent DNA replication
ETL58_03570	COG3677	Transposase
ETL58_03580	COG5484	DNA packaging
ETL58_03585	COG1783	phage Terminase large subunit
ETL58_03705	COG1388	LysM domain
ETL58_03705	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETL58_03705	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_03745	COG1073	alpha beta
ETL58_03750	COG0457	Tetratricopeptide repeat
ETL58_03755	COG1063	alcohol dehydrogenase
ETL58_03760	COG2211	Major facilitator Superfamily
ETL58_03765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETL58_03770	COG1842	Phage shock protein A
ETL58_03775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETL58_03780	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ETL58_03785	COG4260	virion core protein, lumpy skin disease virus
ETL58_03795	COG2814	Major facilitator Superfamily
ETL58_03800	COG1063	alcohol dehydrogenase
ETL58_03805	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ETL58_03810	COG0823	Involved in the tonB-independent uptake of proteins
ETL58_03825	COG2267	carboxylic ester hydrolase activity
ETL58_03835	COG2132	Multicopper oxidase
ETL58_03840	COG1113	amino acid transport
ETL58_03850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETL58_03855	COG0714	Associated with various cellular activities
ETL58_03860	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ETL58_03865	COG1305	Transglutaminase-like
ETL58_03870	COG0519	Catalyzes the synthesis of GMP from XMP
ETL58_03870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ETL58_03885	COG2252	PERMEase
ETL58_03890	COG3064	Membrane
ETL58_03900	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ETL58_03910	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ETL58_03915	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ETL58_03920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ETL58_03925	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ETL58_03930	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETL58_03935	COG0047	phosphoribosylformylglycinamidine synthase activity
ETL58_03940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETL58_03945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ETL58_03950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ETL58_03955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETL58_03960	COG0138	bifunctional purine biosynthesis protein purh
ETL58_03965	COG0151	Belongs to the GarS family
ETL58_03970	COG1522	sequence-specific DNA binding
ETL58_03975	COG0531	amino acid
ETL58_03985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETL58_03990	COG1470	cell adhesion involved in biofilm formation
ETL58_03995	COG4496	protein, YerC YecD
ETL58_04000	COG0069	glutamate synthase activity
ETL58_04005	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ETL58_04010	COG0210	DNA helicase
ETL58_04015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETL58_04020	COG4851	CamS sex pheromone cAM373 precursor
ETL58_04025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETL58_04030	COG1285	pathogenesis
ETL58_04035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETL58_04040	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETL58_04045	COG0154	amidase activity
ETL58_04050	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETL58_04055	COG1309	transcriptional regulator
ETL58_04060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETL58_04065	COG1597	lipid kinase activity
ETL58_04070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETL58_04095	COG0457	Tetratricopeptide repeat
ETL58_04110	COG5444	nuclease activity
ETL58_04115	COG3391	amine dehydrogenase activity
ETL58_04125	COG0457	Tetratricopeptide repeat
ETL58_04135	COG0217	transcriptional regulatory protein
ETL58_04145	COG1309	transcriptional regulator
ETL58_04150	COG3631	Ketosteroid isomerase-related protein
ETL58_04155	COG0702	epimerase
ETL58_04170	COG3546	catalase activity
ETL58_04175	COG0454	-acetyltransferase
ETL58_04185	COG5578	integral membrane protein
ETL58_04190	COG2972	Histidine kinase
ETL58_04195	COG2207	Transcriptional regulator
ETL58_04195	COG4753	response regulator
ETL58_04200	COG1653	transport
ETL58_04205	COG1175	transmembrane transport
ETL58_04210	COG0395	ABC-type sugar transport system, permease component
ETL58_04215	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETL58_04220	COG2207	Transcriptional regulator
ETL58_04225	COG2755	lipolytic protein G-D-S-L family
ETL58_04235	COG5578	integral membrane protein
ETL58_04240	COG3401	FG-GAP repeat protein
ETL58_04245	COG3401	FG-GAP repeat protein
ETL58_04250	COG2755	lipolytic protein G-D-S-L family
ETL58_04255	COG1874	Beta-galactosidase
ETL58_04265	COG1653	transport
ETL58_04270	COG4209	transmembrane transport
ETL58_04275	COG0395	ABC-type sugar transport system, permease component
ETL58_04280	COG1486	melibiose metabolic process
ETL58_04285	COG2323	membrane
ETL58_04290	COG2329	Antibiotic biosynthesis monooxygenase
ETL58_04295	COG0346	lactoylglutathione lyase activity
ETL58_04310	COG5583	Uncharacterized small protein (DUF2292)
ETL58_04315	COG0670	Belongs to the BI1 family
ETL58_04320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETL58_04355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETL58_04355	COG2124	cytochrome p450
ETL58_04360	COG1368	sulfuric ester hydrolase activity
ETL58_04365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ETL58_04370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETL58_04375	COG1442	glycosyl transferase family 8
ETL58_04380	COG1216	Glycosyl transferase, family 2
ETL58_04385	COG1442	glycosyl transferase family 8
ETL58_04390	COG2223	nitrite transmembrane transporter activity
ETL58_04395	COG1011	Hydrolase
ETL58_04400	COG0531	amino acid
ETL58_04405	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_04410	COG0840	transmembrane signaling receptor activity
ETL58_04415	COG0488	(ABC) transporter
ETL58_04425	COG0789	Transcriptional regulator
ETL58_04430	COG2814	Major facilitator Superfamily
ETL58_04445	COG0488	(ABC) transporter
ETL58_04450	COG0513	Belongs to the DEAD box helicase family
ETL58_04455	COG0456	acetyltransferase
ETL58_04460	COG2130	NADP-dependent
ETL58_04470	COG2211	Major facilitator Superfamily
ETL58_04475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETL58_04480	COG1120	ATPase activity
ETL58_04485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_04490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_04495	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ETL58_04510	COG3866	Pectate lyase
ETL58_04515	COG0471	metal ion transport
ETL58_04520	COG3290	protein histidine kinase activity
ETL58_04525	COG4565	transcriptional regulatory protein
ETL58_04530	COG3181	Tripartite tricarboxylate transporter family receptor
ETL58_04535	COG2851	Citrate transporter
ETL58_04540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_04545	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ETL58_04550	COG1254	Belongs to the acylphosphatase family
ETL58_04555	COG2258	MOSC domain
ETL58_04575	COG0024	Methionine aminopeptidase
ETL58_04580	COG1263	PTS System
ETL58_04580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_04585	COG1368	sulfuric ester hydrolase activity
ETL58_04600	COG1115	amino acid carrier protein
ETL58_04605	COG0531	amino acid
ETL58_04620	COG0697	spore germination
ETL58_04625	COG1263	PTS System
ETL58_04625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_04630	COG0366	Alpha amylase catalytic
ETL58_04635	COG2188	Transcriptional regulator
ETL58_04640	COG0778	Nitroreductase
ETL58_04645	COG0737	Belongs to the 5'-nucleotidase family
ETL58_04650	COG0693	protein deglycase activity
ETL58_04655	COG2814	Major facilitator Superfamily
ETL58_04660	COG4840	Belongs to the UPF0435 family
ETL58_04665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETL58_04670	COG4980	gas vesicle protein
ETL58_04675	COG1295	ribonuclease BN
ETL58_04680	COG0477	Major facilitator Superfamily
ETL58_04685	COG0387	Pfam Sodium calcium exchanger
ETL58_04695	COG0668	transmembrane transport
ETL58_04700	COG0535	radical SAM domain protein
ETL58_04710	COG0726	polysaccharide deacetylase
ETL58_04715	COG2084	Dehydrogenase
ETL58_04720	COG0598	Magnesium transport protein CorA
ETL58_04725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ETL58_04730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETL58_04740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETL58_04745	COG4637	Psort location Cytoplasmic, score
ETL58_04755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETL58_04760	COG0022	dehydrogenase e1 component
ETL58_04765	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETL58_04770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETL58_04775	COG3284	Transcriptional regulator
ETL58_04785	COG1742	UPF0060 membrane protein
ETL58_04810	COG4842	Belongs to the WXG100 family
ETL58_04815	COG1486	melibiose metabolic process
ETL58_04820	COG1737	Transcriptional regulator
ETL58_04825	COG1263	PTS System
ETL58_04825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_04830	COG1132	(ABC) transporter
ETL58_04835	COG1132	(ABC) transporter
ETL58_04840	COG2259	Doxx family
ETL58_04845	COG2514	catechol 2,3-dioxygenase activity
ETL58_04850	COG4585	Histidine kinase
ETL58_04855	COG2197	response regulator
ETL58_04860	COG1131	(ABC) transporter
ETL58_04865	COG1511	domain protein
ETL58_04865	COG0842	Transport permease protein
ETL58_04870	COG0842	Transport permease protein
ETL58_04875	COG1695	Transcriptional regulator
ETL58_04880	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ETL58_04885	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ETL58_04890	COG2318	DinB family
ETL58_04895	COG2814	Major facilitator Superfamily
ETL58_04900	COG1846	Transcriptional regulator
ETL58_04905	COG0392	lysyltransferase activity
ETL58_04905	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ETL58_04910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_04915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_04920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_04925	COG0384	phenazine biosynthesis protein PhzF
ETL58_04930	COG0778	Nitroreductase
ETL58_04945	COG1090	epimerase
ETL58_04950	COG2137	regulation of response to DNA damage stimulus
ETL58_04960	COG2814	Major facilitator Superfamily
ETL58_04975	COG3103	Sh3 type 3 domain protein
ETL58_04980	COG5658	integral membrane protein
ETL58_04985	COG0596	Alpha beta hydrolase
ETL58_04990	COG0463	Glycosyl transferase, family 2
ETL58_04995	COG4485	Bacterial membrane protein, YfhO
ETL58_05000	COG1988	membrane-bound metal-dependent
ETL58_05005	COG1194	a g-specific adenine glycosylase
ETL58_05015	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_05030	COG3557	Belongs to the UPF0374 family
ETL58_05035	COG1132	(ABC) transporter
ETL58_05040	COG4129	membrane
ETL58_05045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETL58_05050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETL58_05055	COG0735	belongs to the Fur family
ETL58_05165	COG4326	sporulation control protein
ETL58_05175	COG5577	PFAM Coat F domain
ETL58_05180	COG3340	Belongs to the peptidase S51 family
ETL58_05185	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ETL58_05190	COG0277	FAD linked oxidase domain protein
ETL58_05200	COG0753	catalase activity
ETL58_05205	COG1116	anion transmembrane transporter activity
ETL58_05210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETL58_05215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETL58_05220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_05230	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ETL58_05240	COG1476	TRANSCRIPTIONal
ETL58_05250	COG3382	B3 4 domain protein
ETL58_05255	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ETL58_05265	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ETL58_05270	COG0789	Transcriptional regulator
ETL58_05275	COG1664	Polymer-forming cytoskeletal
ETL58_05280	COG1664	Polymer-forming cytoskeletal
ETL58_05285	COG2766	serine protein kinase
ETL58_05290	COG2718	Belongs to the UPF0229 family
ETL58_05295	COG1846	Transcriptional regulator
ETL58_05300	COG1566	PFAM secretion protein HlyD family protein
ETL58_05305	COG2814	Major facilitator Superfamily
ETL58_05310	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETL58_05330	COG1725	Transcriptional regulator
ETL58_05335	COG1131	(ABC) transporter
ETL58_05340	COG1131	(ABC) transporter
ETL58_05345	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETL58_05350	COG1278	Cold shock
ETL58_05360	COG1464	Belongs to the NlpA lipoprotein family
ETL58_05365	COG3706	GGDEF domain
ETL58_05370	COG1823	symporter activity
ETL58_05390	COG5577	PFAM Coat F domain
ETL58_05395	COG1525	nuclease
ETL58_05395	COG4085	toxin activity
ETL58_05395	COG0737	Belongs to the 5'-nucleotidase family
ETL58_05400	COG3764	Sortase (surface protein transpeptidase)
ETL58_05405	COG0564	pseudouridine synthase activity
ETL58_05415	COG0517	IMP dehydrogenase activity
ETL58_05420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETL58_05425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETL58_05425	COG3153	acetyltransferase
ETL58_05430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETL58_05435	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ETL58_05440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETL58_05445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ETL58_05450	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ETL58_05455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETL58_05460	COG4585	Histidine kinase
ETL58_05460	COG2203	Gaf domain
ETL58_05465	COG2197	response regulator
ETL58_05470	COG0431	NADPH-dependent FMN reductase
ETL58_05485	COG1388	LysM domain
ETL58_05485	COG0791	NLP P60 protein
ETL58_05490	COG1959	2 iron, 2 sulfur cluster binding
ETL58_05495	COG0668	transmembrane transport
ETL58_05500	COG2719	SpoVR family
ETL58_05505	COG1785	Belongs to the alkaline phosphatase family
ETL58_05510	COG0791	NLP P60 protein
ETL58_05510	COG1388	LysM domain
ETL58_05515	COG0583	DNA-binding transcription factor activity
ETL58_05520	COG0372	Belongs to the citrate synthase family
ETL58_05525	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_05530	COG0531	amino acid
ETL58_05535	COG0733	neurotransmitter:sodium symporter activity
ETL58_05540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_05545	COG0456	acetyltransferase
ETL58_05560	COG1595	DNA-templated transcription, initiation
ETL58_05565	COG0667	Aldo Keto reductase
ETL58_05570	COG0204	Acyl-transferase
ETL58_05575	COG1253	flavin adenine dinucleotide binding
ETL58_05580	COG0789	Transcriptional regulator
ETL58_05585	COG0436	Aminotransferase
ETL58_05590	COG1253	flavin adenine dinucleotide binding
ETL58_05595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETL58_05600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETL58_05605	COG0584	glycerophosphoryl diester phosphodiesterase
ETL58_05615	COG0668	transmembrane transport
ETL58_05620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ETL58_05625	COG0726	polysaccharide deacetylase
ETL58_05630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETL58_05635	COG1757	Na H antiporter
ETL58_05640	COG0589	response to stress
ETL58_05650	COG1132	(ABC) transporter
ETL58_05655	COG1132	(ABC) transporter
ETL58_05660	COG0702	epimerase
ETL58_05680	COG0189	ligase activity
ETL58_05685	COG0189	ligase activity
ETL58_05690	COG4399	Belongs to the UPF0754 family
ETL58_05695	COG3679	Belongs to the UPF0342 family
ETL58_05700	COG4335	DNA alkylation repair
ETL58_05705	COG0561	phosphatase activity
ETL58_05710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETL58_05715	COG0475	glutathione-regulated potassium exporter activity
ETL58_05720	COG0490	domain, Protein
ETL58_05730	COG1024	Enoyl-CoA hydratase
ETL58_05740	COG4152	abc transporter atp-binding protein
ETL58_05745	COG1668	transmembrane transport
ETL58_05750	COG0420	3'-5' exonuclease activity
ETL58_05755	COG4717	serine-type aminopeptidase activity
ETL58_05760	COG3481	metal-dependent phosphohydrolase, HD sub domain
ETL58_05770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETL58_05800	COG1846	Transcriptional regulator
ETL58_05805	COG4980	gas vesicle protein
ETL58_05820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ETL58_05825	COG0537	adenosine 5'-monophosphoramidase activity
ETL58_05830	COG1131	(ABC) transporter
ETL58_05835	COG4473	ABC transporter
ETL58_05845	COG1473	amidohydrolase
ETL58_05850	COG3069	C4-dicarboxylate transmembrane transporter activity
ETL58_05860	COG2329	Antibiotic biosynthesis monooxygenase
ETL58_05865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETL58_05870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ETL58_05885	COG1309	transcriptional regulator
ETL58_05890	COG1511	domain protein
ETL58_05895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETL58_05900	COG4377	Putative membrane peptidase family (DUF2324)
ETL58_05910	COG1363	Peptidase, m42
ETL58_05915	COG4405	Protein conserved in bacteria
ETL58_05920	COG1301	dicarboxylic acid transport
ETL58_05930	COG1234	tRNA 3'-trailer cleavage
ETL58_05935	COG0095	Lipoate-protein ligase
ETL58_05940	COG0702	epimerase
ETL58_05945	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_05955	COG0501	Belongs to the peptidase M48B family
ETL58_05965	COG0456	acetyltransferase
ETL58_05970	COG0604	alcohol dehydrogenase
ETL58_05975	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ETL58_05980	COG0406	alpha-ribazole phosphatase activity
ETL58_05985	COG0183	Belongs to the thiolase family
ETL58_05990	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_05995	COG1268	BioY protein
ETL58_06000	COG0840	transmembrane signaling receptor activity
ETL58_06005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETL58_06005	COG0723	plastoquinol--plastocyanin reductase activity
ETL58_06010	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_06020	COG4903	ComK protein
ETL58_06025	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_06035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETL58_06050	COG0398	Pfam SNARE associated Golgi protein
ETL58_06055	COG0681	Belongs to the peptidase S26 family
ETL58_06060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETL58_06065	COG1846	Transcriptional regulator
ETL58_06070	COG0738	Major facilitator superfamily
ETL58_06075	COG0673	inositol 2-dehydrogenase activity
ETL58_06080	COG0561	phosphatase activity
ETL58_06085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETL58_06090	COG1609	Transcriptional regulator
ETL58_06095	COG3180	Ammonia monooxygenase
ETL58_06100	COG2814	Major facilitator Superfamily
ETL58_06100	COG0477	Major facilitator Superfamily
ETL58_06105	COG4533	DNA binding
ETL58_06115	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ETL58_06120	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ETL58_06125	COG1074	ATP-dependent DNA helicase activity
ETL58_06130	COG0420	3'-5' exonuclease activity
ETL58_06135	COG0419	ATPase involved in DNA repair
ETL58_06140	COG1403	HNH endonuclease
ETL58_06180	COG5337	Spore coat protein CotH
ETL58_06185	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETL58_06195	COG1404	Belongs to the peptidase S8 family
ETL58_06205	COG0367	asparagine synthase
ETL58_06210	COG2318	DinB family
ETL58_06215	COG1562	ergosterol biosynthetic process
ETL58_06220	COG0534	Mate efflux family protein
ETL58_06225	COG1917	Cupin 2, conserved barrel domain protein
ETL58_06225	COG2207	Transcriptional regulator
ETL58_06230	COG1609	Transcriptional regulator
ETL58_06235	COG0673	inositol 2-dehydrogenase activity
ETL58_06240	COG2318	DinB family
ETL58_06245	COG1279	arginine transmembrane transporter activity
ETL58_06250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_06255	COG1357	PFAM Pentapeptide repeats (8 copies)
ETL58_06260	COG2267	carboxylic ester hydrolase activity
ETL58_06265	COG0529	Catalyzes the synthesis of activated sulfate
ETL58_06270	COG2046	Belongs to the sulfate adenylyltransferase family
ETL58_06275	COG0175	sulfate reduction
ETL58_06280	COG2045	Belongs to the ComB family
ETL58_06285	COG1809	phosphosulfolactate synthase activity
ETL58_06290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_06295	COG4948	Mandelate Racemase Muconate Lactonizing
ETL58_06300	COG2814	Major facilitator Superfamily
ETL58_06305	COG0454	-acetyltransferase
ETL58_06310	COG2153	protein acetylation
ETL58_06315	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ETL58_06315	COG0646	methionine synthase
ETL58_06320	COG1666	GTP binding
ETL58_06325	COG2996	Protein conserved in bacteria
ETL58_06345	COG1695	Transcriptional regulator
ETL58_06360	COG3227	Zinc metalloprotease (Elastase)
ETL58_06365	COG1307	EDD domain protein, DegV family
ETL58_06370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_06385	COG0561	phosphatase activity
ETL58_06390	COG1073	alpha beta
ETL58_06395	COG2151	metal-sulfur cluster biosynthetic enzyme
ETL58_06405	COG0277	FAD linked oxidase domain protein
ETL58_06410	COG2271	Major facilitator Superfamily
ETL58_06415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ETL58_06430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETL58_06435	COG0505	Belongs to the CarA family
ETL58_06440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETL58_06445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ETL58_06460	COG2267	carboxylic ester hydrolase activity
ETL58_06470	COG1744	ABC transporter substrate-binding protein PnrA-like
ETL58_06485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETL58_06490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETL58_06495	COG5504	Zn-dependent protease
ETL58_06500	COG0444	Belongs to the ABC transporter superfamily
ETL58_06505	COG4608	Belongs to the ABC transporter superfamily
ETL58_06515	COG0601	transmembrane transport
ETL58_06520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETL58_06530	COG0180	Tryptophanyl-tRNA synthetase
ETL58_06535	COG4166	transmembrane transport
ETL58_06540	COG0601	transmembrane transport
ETL58_06545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETL58_06550	COG0444	Belongs to the ABC transporter superfamily
ETL58_06555	COG4608	Belongs to the ABC transporter superfamily
ETL58_06560	COG2814	Major facilitator Superfamily
ETL58_06565	COG0456	acetyltransferase
ETL58_06570	COG1393	Belongs to the ArsC family
ETL58_06575	COG0861	Integral membrane protein TerC family
ETL58_06585	COG4862	establishment of competence for transformation
ETL58_06595	COG4469	Competence protein
ETL58_06600	COG1164	Oligoendopeptidase f
ETL58_06620	COG2346	COG2346, Truncated hemoglobins
ETL58_06625	COG0741	lytic transglycosylase activity
ETL58_06630	COG4116	CYTH
ETL58_06640	COG2357	RelA SpoT domain protein
ETL58_06645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETL58_06650	COG0564	pseudouridine synthase activity
ETL58_06655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ETL58_06660	COG0475	glutathione-regulated potassium exporter activity
ETL58_06660	COG0569	domain protein
ETL58_06665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ETL58_06670	COG0352	thiamine-phosphate diphosphorylase activity
ETL58_06675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETL58_06680	COG2104	thiamine diphosphate biosynthetic process
ETL58_06685	COG2022	thiamine diphosphate biosynthetic process
ETL58_06690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETL58_06695	COG0351	phosphomethylpyrimidine kinase
ETL58_06700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ETL58_06755	COG0210	DNA helicase
ETL58_06765	COG2153	protein acetylation
ETL58_06770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETL58_06775	COG2382	esterase
ETL58_06780	COG0626	cystathionine gamma-synthase activity
ETL58_06785	COG0626	cystathionine gamma-synthase activity
ETL58_06790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_06795	COG5505	Protein of unknown function (DUF819)
ETL58_06830	COG5444	nuclease activity
ETL58_06855	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETL58_06860	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_06870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_06870	COG3711	transcriptional antiterminator
ETL58_06875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETL58_06875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETL58_06875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_06880	COG1482	cell wall glycoprotein biosynthetic process
ETL58_06890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_06900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ETL58_06920	COG0109	protoheme IX farnesyltransferase activity
ETL58_06930	COG0726	polysaccharide deacetylase
ETL58_06945	COG5504	Zn-dependent protease
ETL58_06950	COG2205	protein histidine kinase activity
ETL58_06960	COG3383	formate dehydrogenase (NAD+) activity
ETL58_06965	COG2427	Protein of unknown function (DUF1641)
ETL58_06975	COG1051	belongs to the nudix hydrolase family
ETL58_06985	COG2124	cytochrome p450
ETL58_06990	COG1819	glycosyl
ETL58_07000	COG1587	Uroporphyrinogen-III synthase
ETL58_07005	COG0390	transport system, permease component
ETL58_07010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETL58_07015	COG0697	spore germination
ETL58_07020	COG4297	protein containing double-stranded beta helix domain
ETL58_07030	COG1252	NADH dehydrogenase
ETL58_07035	COG1904	glucuronate isomerase
ETL58_07040	COG2211	Major facilitator Superfamily
ETL58_07045	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ETL58_07050	COG1063	alcohol dehydrogenase
ETL58_07055	COG1312	Catalyzes the dehydration of D-mannonate
ETL58_07060	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_07065	COG2271	Major facilitator Superfamily
ETL58_07070	COG1609	Transcriptional regulator
ETL58_07075	COG0246	Mannitol dehydrogenase
ETL58_07080	COG2721	sulfolactate sulfo-lyase activity
ETL58_07085	COG0730	response to heat
ETL58_07090	COG2318	DinB family
ETL58_07095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETL58_07100	COG0457	Tetratricopeptide repeat
ETL58_07110	COG2350	Protein conserved in bacteria
ETL58_07115	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETL58_07115	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_07115	COG1388	LysM domain
ETL58_07125	COG4195	phage-related replication protein
ETL58_07130	COG3546	catalase activity
ETL58_07135	COG2856	Zn peptidase
ETL58_07140	COG1396	sequence-specific DNA binding
ETL58_07150	COG1522	sequence-specific DNA binding
ETL58_07155	COG1484	DNA-dependent DNA replication
ETL58_07175	COG1595	DNA-templated transcription, initiation
ETL58_07180	COG5484	DNA packaging
ETL58_07180	COG3728	DNA packaging
ETL58_07185	COG1783	phage Terminase large subunit
ETL58_07190	COG5518	Phage portal protein
ETL58_07195	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ETL58_07200	COG4653	Phage capsid family
ETL58_07250	COG5412	phage tail tape measure protein
ETL58_07250	COG3953	SLT domain
ETL58_07255	COG1652	LysM domain
ETL58_07260	COG4193	domain, Protein
ETL58_07270	COG3628	GPW Gp25 family protein
ETL58_07275	COG3299	homolog of phage Mu protein gp47
ETL58_07280	COG3778	Protein conserved in bacteria
ETL58_07320	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_07320	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETL58_07340	COG0306	phosphate transporter
ETL58_07345	COG1392	Phosphate transport regulator
ETL58_07350	COG0531	amino acid
ETL58_07355	COG0346	lactoylglutathione lyase activity
ETL58_07360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETL58_07365	COG0463	Glycosyl transferase, family 2
ETL58_07370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETL58_07375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETL58_07380	COG2362	D-Aminopeptidase
ETL58_07385	COG0601	transmembrane transport
ETL58_07390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETL58_07395	COG0444	Belongs to the ABC transporter superfamily
ETL58_07400	COG4166	transmembrane transport
ETL58_07405	COG1619	proteins homologs of microcin C7 resistance protein MccF
ETL58_07410	COG4948	Mandelate Racemase Muconate Lactonizing
ETL58_07415	COG0791	NLP P60 protein
ETL58_07420	COG4608	Belongs to the ABC transporter superfamily
ETL58_07425	COG2706	6-phosphogluconolactonase activity
ETL58_07430	COG1834	amidinotransferase
ETL58_07435	COG1607	acyl-coa hydrolase
ETL58_07440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ETL58_07440	COG1017	nitric oxide dioxygenase activity
ETL58_07450	COG2323	membrane
ETL58_07455	COG2318	DinB family
ETL58_07460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_07465	COG2076	Multidrug Resistance protein
ETL58_07470	COG2076	Multidrug Resistance protein
ETL58_07475	COG0788	formyltetrahydrofolate deformylase activity
ETL58_07480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETL58_07485	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ETL58_07490	COG1764	response to oxidative stress
ETL58_07495	COG1846	Transcriptional regulator
ETL58_07500	COG1764	response to oxidative stress
ETL58_07510	COG0590	tRNA wobble adenosine to inosine editing
ETL58_07515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETL58_07520	COG1404	Belongs to the peptidase S8 family
ETL58_07525	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_07530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETL58_07535	COG1122	ATPase activity
ETL58_07540	COG4721	ABC-type cobalt transport system, permease component
ETL58_07550	COG0745	RESPONSE REGULATOR receiver
ETL58_07555	COG5002	protein histidine kinase activity
ETL58_07555	COG3850	Histidine kinase
ETL58_07560	COG3212	peptidase
ETL58_07565	COG3212	peptidase
ETL58_07575	COG2239	Acts as a magnesium transporter
ETL58_07580	COG0789	Transcriptional regulator
ETL58_07595	COG1846	Transcriptional regulator
ETL58_07600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETL58_07605	COG0726	polysaccharide deacetylase
ETL58_07610	COG1408	metallophosphoesterase
ETL58_07620	COG0463	Glycosyl transferase, family 2
ETL58_07625	COG3285	dna ligase
ETL58_07625	COG1793	dna ligase
ETL58_07630	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ETL58_07635	COG3300	MHYT domain
ETL58_07635	COG5001	Diguanylate cyclase
ETL58_07640	COG0586	Pfam SNARE associated Golgi protein
ETL58_07645	COG0861	Integral membrane protein TerC family
ETL58_07650	COG1191	sigma factor activity
ETL58_07670	COG0501	Belongs to the peptidase M48B family
ETL58_07675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETL58_07690	COG3594	Acyltransferase
ETL58_07695	COG5002	protein histidine kinase activity
ETL58_07700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETL58_07710	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ETL58_07715	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ETL58_07720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETL58_07725	COG0436	Aminotransferase
ETL58_07730	COG1850	ribulose-bisphosphate carboxylase activity
ETL58_07735	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ETL58_07740	COG0235	Class ii aldolase
ETL58_07745	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ETL58_07750	COG3339	Conserved Protein
ETL58_07765	COG3852	Histidine kinase
ETL58_07770	COG1846	Transcriptional regulator
ETL58_07775	COG1360	Flagellar Motor Protein
ETL58_07780	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ETL58_07790	COG0542	response to heat
ETL58_07795	COG3949	Membrane
ETL58_07800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ETL58_07805	COG0720	synthase
ETL58_07810	COG0602	queuosine metabolic process
ETL58_07815	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ETL58_07820	COG1733	regulation of RNA biosynthetic process
ETL58_07825	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_07835	COG1388	LysM domain
ETL58_07840	COG3858	chitin binding
ETL58_07850	COG4873	Protein conserved in bacteria
ETL58_07860	COG3773	Cell wall hydrolase
ETL58_07865	COG2244	polysaccharide biosynthetic process
ETL58_07870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_07875	COG2217	Heavy metal translocating P-type atpase
ETL58_07885	COG0006	proline dipeptidase activity
ETL58_07890	COG1609	Transcriptional regulator
ETL58_07895	COG3711	transcriptional antiterminator
ETL58_07900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_07900	COG2190	(PTS) system
ETL58_07900	COG1263	PTS System
ETL58_07905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_07910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETL58_07920	COG1533	DNA photolyase activity
ETL58_07925	COG0456	acetyltransferase
ETL58_07930	COG0840	transmembrane signaling receptor activity
ETL58_07935	COG2084	Dehydrogenase
ETL58_07940	COG2340	Cysteine-rich secretory protein family
ETL58_07945	COG0768	penicillin binding
ETL58_07950	COG4191	Histidine kinase
ETL58_07955	COG0436	Aminotransferase
ETL58_07965	COG0784	Response regulator, receiver
ETL58_07965	COG0835	chemotaxis
ETL58_07975	COG2814	Major facilitator Superfamily
ETL58_07980	COG1376	ErfK ybiS ycfS ynhG family protein
ETL58_07985	COG1408	metallophosphoesterase
ETL58_07990	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_07995	COG2200	EAL domain
ETL58_08000	COG4703	Protein of unknown function (DUF1797)
ETL58_08005	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ETL58_08015	COG0517	IMP dehydrogenase activity
ETL58_08020	COG0583	DNA-binding transcription factor activity
ETL58_08025	COG0716	FMN binding
ETL58_08035	COG0716	FMN binding
ETL58_08040	COG2171	N-acyltransferase activity
ETL58_08045	COG1473	amidohydrolase
ETL58_08055	COG0668	transmembrane transport
ETL58_08060	COG0450	alkyl hydroperoxide reductase
ETL58_08065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_08080	COG0746	molybdenum cofactor guanylyltransferase activity
ETL58_08085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETL58_08090	COG0303	'Molybdopterin
ETL58_08095	COG1763	Mo-molybdopterin cofactor biosynthetic process
ETL58_08100	COG0314	molybdopterin synthase activity
ETL58_08105	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ETL58_08110	COG1132	(ABC) transporter
ETL58_08115	COG1132	(ABC) transporter
ETL58_08125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETL58_08130	COG1136	(ABC) transporter
ETL58_08135	COG0577	efflux transmembrane transporter activity
ETL58_08140	COG1349	DNA-binding transcription factor activity
ETL58_08145	COG1105	Belongs to the carbohydrate kinase PfkB family
ETL58_08150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_08150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETL58_08150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETL58_08155	COG0681	Belongs to the peptidase S26 family
ETL58_08165	COG0488	(ABC) transporter
ETL58_08170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ETL58_08175	COG2309	aminopeptidase activity
ETL58_08185	COG1077	Cell shape determining protein MreB Mrl
ETL58_08190	COG2002	toxin-antitoxin pair type II binding
ETL58_08195	COG3852	Histidine kinase
ETL58_08200	COG2105	PFAM AIG2 family protein
ETL58_08200	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ETL58_08205	COG0569	domain protein
ETL58_08210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETL58_08215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ETL58_08225	COG0561	phosphatase activity
ETL58_08230	COG0242	peptide deformylase activity
ETL58_08240	COG0497	DNA recombination
ETL58_08245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETL58_08250	COG0022	dehydrogenase e1 component
ETL58_08255	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETL58_08260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETL58_08265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_08275	COG1982	Orn Lys Arg decarboxylase major
ETL58_08280	COG4476	Belongs to the UPF0223 family
ETL58_08285	COG4493	Belongs to the UPF0637 family
ETL58_08295	COG0483	inositol monophosphate 1-phosphatase activity
ETL58_08305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ETL58_08325	COG1595	DNA-templated transcription, initiation
ETL58_08355	COG4896	Protein conserved in bacteria
ETL58_08365	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ETL58_08370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETL58_08375	COG2066	Belongs to the glutaminase family
ETL58_08380	COG4838	Belongs to the UPF0358 family
ETL58_08385	COG0772	Belongs to the SEDS family
ETL58_08390	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ETL58_08395	COG1612	heme a metabolic process
ETL58_08400	COG0109	protoheme IX farnesyltransferase activity
ETL58_08405	COG2010	Cytochrome c
ETL58_08405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETL58_08410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETL58_08415	COG1845	cytochrome c oxidase, subunit III
ETL58_08420	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ETL58_08425	COG3336	cytochrome c oxidase
ETL58_08435	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ETL58_08440	COG2340	Cysteine-rich secretory protein family
ETL58_08455	COG3679	Belongs to the UPF0342 family
ETL58_08460	COG4471	UPF0298 protein
ETL58_08465	COG0742	ribosomal rna small subunit methyltransferase
ETL58_08470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ETL58_08475	COG3314	Sporulation integral membrane protein YlbJ
ETL58_08480	COG1752	Esterase of the alpha-beta hydrolase superfamily
ETL58_08485	COG3480	Lon protease (S16) C-terminal proteolytic domain
ETL58_08490	COG1323	Belongs to the UPF0348 family
ETL58_08500	COG1399	metal-binding, possibly nucleic acid-binding protein
ETL58_08505	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ETL58_08515	COG0454	-acetyltransferase
ETL58_08520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ETL58_08525	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ETL58_08530	COG2001	Belongs to the MraZ family
ETL58_08535	COG0275	rRNA processing
ETL58_08540	COG4839	cell division protein FtsL
ETL58_08550	COG0768	penicillin binding
ETL58_08555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ETL58_08560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETL58_08565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ETL58_08570	COG0772	Belongs to the SEDS family
ETL58_08575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETL58_08580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ETL58_08585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ETL58_08590	COG3879	Bacterial protein of unknown function (DUF881)
ETL58_08595	COG3879	Bacterial protein of unknown function (DUF881)
ETL58_08600	COG3856	small basic protein
ETL58_08605	COG0849	cell division
ETL58_08610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ETL58_08615	COG1404	Belongs to the peptidase S8 family
ETL58_08615	COG4412	M6 family metalloprotease domain protein
ETL58_08625	COG1191	sigma factor activity
ETL58_08630	COG1191	sigma factor activity
ETL58_08635	COG1119	ATPase activity
ETL58_08640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETL58_08645	COG1873	PFAM PRC-barrel domain
ETL58_08655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ETL58_08660	COG1799	cell septum assembly
ETL58_08665	COG0762	integral membrane protein
ETL58_08670	COG2302	S4 RNA-binding domain
ETL58_08675	COG3599	regulation of cell shape
ETL58_08680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ETL58_08685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETL58_08690	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ETL58_08695	COG0564	pseudouridine synthase activity
ETL58_08700	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ETL58_08705	COG2233	PERMEase
ETL58_08710	COG0540	Belongs to the ATCase OTCase family
ETL58_08715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETL58_08720	COG0505	Belongs to the CarA family
ETL58_08725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETL58_08730	COG0543	2 iron, 2 sulfur cluster binding
ETL58_08735	COG0167	dihydroorotate dehydrogenase activity
ETL58_08740	COG0284	orotidine-5'-phosphate decarboxylase activity
ETL58_08745	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ETL58_08750	COG0175	sulfate reduction
ETL58_08755	COG0306	phosphate transporter
ETL58_08760	COG2046	Belongs to the sulfate adenylyltransferase family
ETL58_08765	COG0529	Catalyzes the synthesis of activated sulfate
ETL58_08770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETL58_08775	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
ETL58_08780	COG1648	precorrin-2 dehydrogenase activity
ETL58_08790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETL58_08795	COG1561	YicC-like family, N-terminal region
ETL58_08800	COG2052	Domain of unknown function (DUF370)
ETL58_08805	COG0194	GDP metabolic process
ETL58_08810	COG1758	RNA polymerase activity
ETL58_08815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETL58_08820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETL58_08825	COG0242	peptide deformylase activity
ETL58_08830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ETL58_08835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETL58_08835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETL58_08840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ETL58_08845	COG0631	protein serine/threonine phosphatase activity
ETL58_08850	COG2815	serine threonine protein kinase
ETL58_08850	COG0515	serine threonine protein kinase
ETL58_08855	COG1162	GTPase activity
ETL58_08860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ETL58_08865	COG1564	THIamine pyrophosphokinase
ETL58_08875	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ETL58_08880	COG1302	Protein conserved in bacteria
ETL58_08885	COG1461	Dihydroxyacetone kinase
ETL58_08890	COG1760	l-serine dehydratase
ETL58_08895	COG1760	l-serine dehydratase
ETL58_08900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETL58_08905	COG1349	DNA-binding transcription factor activity
ETL58_08905	COG2050	protein possibly involved in aromatic compounds catabolism
ETL58_08910	COG0416	fatty acid biosynthetic process
ETL58_08915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETL58_08920	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_08925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_08930	COG0571	ribonuclease III activity
ETL58_08935	COG1196	nuclear chromosome segregation
ETL58_08940	COG0552	protein localization to endoplasmic reticulum
ETL58_08950	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ETL58_08955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETL58_08960	COG0228	four-way junction DNA binding
ETL58_08965	COG1837	Belongs to the UPF0109 family
ETL58_08975	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ETL58_08980	COG0336	Belongs to the RNA methyltransferase TrmD family
ETL58_08985	COG0335	large ribosomal subunit rRNA binding
ETL58_08990	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETL58_08995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ETL58_09005	COG2257	FlhB HrpN YscU SpaS Family
ETL58_09010	COG0045	succinate-CoA ligase (ADP-forming) activity
ETL58_09015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ETL58_09020	COG0758	DNA mediated transformation
ETL58_09025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETL58_09030	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ETL58_09035	COG4974	Belongs to the 'phage' integrase family
ETL58_09040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ETL58_09045	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ETL58_09050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ETL58_09055	COG1815	bacterial-type flagellum-dependent cell motility
ETL58_09060	COG1558	bacterial-type flagellum-dependent cell motility
ETL58_09065	COG1677	Flagellar hook-basal body complex protein FliE
ETL58_09070	COG1766	The M ring may be actively involved in energy transduction
ETL58_09075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETL58_09080	COG1317	bacterial-type flagellum organization
ETL58_09085	COG1157	protein secretion by the type III secretion system
ETL58_09090	COG2882	bacterial-type flagellum organization
ETL58_09095	COG3334	PFAM MgtE intracellular
ETL58_09100	COG3144	bacterial-type flagellum assembly
ETL58_09105	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ETL58_09110	COG4786	Flagellar basal body rod
ETL58_09115	COG1582	Flagellar protein (FlbD)
ETL58_09120	COG1580	Controls the rotational direction of flagella during chemotaxis
ETL58_09125	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETL58_09130	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETL58_09130	COG1776	CheC inhibitor of MCP methylation
ETL58_09135	COG2201	protein-glutamate methylesterase activity
ETL58_09140	COG3190	flagellar
ETL58_09145	COG1338	Plays a role in the flagellum-specific transport system
ETL58_09150	COG1987	bacterial-type flagellum assembly
ETL58_09155	COG1684	flagellar biosynthetic protein fliR
ETL58_09160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETL58_09165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETL58_09170	COG1419	protein localization to endoplasmic reticulum
ETL58_09175	COG0455	bacterial-type flagellum organization
ETL58_09180	COG2201	protein-glutamate methylesterase activity
ETL58_09185	COG0643	Histidine kinase
ETL58_09185	COG2198	Histidine kinase
ETL58_09190	COG0835	chemotaxis
ETL58_09195	COG1776	CheC inhibitor of MCP methylation
ETL58_09200	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ETL58_09205	COG1191	sigma factor activity
ETL58_09215	COG0052	Belongs to the universal ribosomal protein uS2 family
ETL58_09220	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ETL58_09225	COG0528	UMP kinase activity
ETL58_09230	COG0233	cytoplasmic translational termination
ETL58_09235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ETL58_09240	COG4589	Belongs to the CDS family
ETL58_09245	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ETL58_09250	COG0750	zinc metalloprotease
ETL58_09255	COG0442	prolyl-tRNA aminoacylation
ETL58_09260	COG2176	DNA-directed DNA polymerase activity
ETL58_09265	COG0779	Required for maturation of 30S ribosomal subunits
ETL58_09270	COG0195	Participates in both transcription termination and antitermination
ETL58_09275	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ETL58_09280	COG1358	cellular component organization or biogenesis
ETL58_09285	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ETL58_09290	COG1550	Protein conserved in bacteria
ETL58_09295	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ETL58_09300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ETL58_09305	COG0196	riboflavin kinase activity
ETL58_09310	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ETL58_09315	COG1185	polyribonucleotide nucleotidyltransferase activity
ETL58_09320	COG0726	polysaccharide deacetylase
ETL58_09325	COG0612	Peptidase, M16
ETL58_09330	COG1873	PFAM PRC-barrel domain
ETL58_09335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETL58_09340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETL58_09345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ETL58_09350	COG0527	aspartate kinase activity
ETL58_09355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETL58_09360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ETL58_09365	COG0740	serine-type endopeptidase activity
ETL58_09375	COG1674	ftsk spoiiie
ETL58_09375	COG4980	gas vesicle protein
ETL58_09380	COG2188	Transcriptional regulator
ETL58_09385	COG2814	Major facilitator Superfamily
ETL58_09390	COG0612	Peptidase, M16
ETL58_09395	COG0612	Peptidase, M16
ETL58_09400	COG0300	oxidoreductase activity
ETL58_09415	COG1426	Protein conserved in bacteria
ETL58_09420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETL58_09425	COG1546	Belongs to the CinA family
ETL58_09425	COG1058	Belongs to the CinA family
ETL58_09430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ETL58_09435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETL58_09440	COG1418	mRNA catabolic process
ETL58_09445	COG1692	metallophosphoesterase
ETL58_09450	COG2359	stage V sporulation protein S
ETL58_09455	COG1063	alcohol dehydrogenase
ETL58_09460	COG0156	8-amino-7-oxononanoate synthase activity
ETL58_09465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETL58_09470	COG4550	Control of competence regulator ComK, YlbF/YmcA
ETL58_09480	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ETL58_09485	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ETL58_09500	COG3226	Transcriptional regulator
ETL58_09505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_09515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETL58_09520	COG3321	synthase
ETL58_09525	COG2070	2-Nitropropane dioxygenase
ETL58_09525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETL58_09530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_09535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETL58_09540	COG3425	synthase
ETL58_09545	COG1024	Enoyl-CoA hydratase
ETL58_09550	COG1024	Enoyl-CoA hydratase
ETL58_09555	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_09555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_09555	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_09555	COG3321	synthase
ETL58_09555	COG0300	oxidoreductase activity
ETL58_09560	COG4221	oxidoreductase activity
ETL58_09560	COG3321	synthase
ETL58_09560	COG0300	oxidoreductase activity
ETL58_09560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_09565	COG3321	synthase
ETL58_09565	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_09565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_09565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_09565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETL58_09570	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_09570	COG4221	oxidoreductase activity
ETL58_09570	COG3321	synthase
ETL58_09570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_09575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_09575	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ETL58_09575	COG3321	synthase
ETL58_09575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ETL58_09580	COG2124	cytochrome p450
ETL58_09590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_09595	COG1404	Belongs to the peptidase S8 family
ETL58_09605	COG4195	phage-related replication protein
ETL58_09610	COG1764	response to oxidative stress
ETL58_09615	COG2076	Multidrug Resistance protein
ETL58_09620	COG2076	Multidrug Resistance protein
ETL58_09635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ETL58_09640	COG1923	regulation of RNA biosynthetic process
ETL58_09655	COG1780	Probably involved in ribonucleotide reductase function
ETL58_09660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETL58_09665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETL58_09670	COG4112	unkown
ETL58_09675	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_09685	COG0464	growth
ETL58_09690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETL58_09695	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ETL58_09700	COG0789	Transcriptional regulator
ETL58_09705	COG0174	glutamine synthetase
ETL58_09725	COG4824	toxin secretion phage lysis holin
ETL58_09755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_09770	COG3655	Transcriptional regulator
ETL58_09785	COG0135	phosphoribosylanthranilate isomerase activity
ETL58_09790	COG2211	Major facilitator Superfamily
ETL58_09795	COG3507	Belongs to the glycosyl hydrolase 43 family
ETL58_09800	COG1940	carbohydrate kinase activity
ETL58_09805	COG2115	Belongs to the xylose isomerase family
ETL58_09810	COG1070	Carbohydrate kinase
ETL58_09820	COG1525	nuclease
ETL58_09825	COG2814	Major facilitator Superfamily
ETL58_09830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ETL58_09840	COG0756	dUTP diphosphatase activity
ETL58_09880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETL58_09895	COG3832	glyoxalase III activity
ETL58_09910	COG0697	spore germination
ETL58_09915	COG0531	amino acid
ETL58_09945	COG4195	phage-related replication protein
ETL58_09955	COG0346	lactoylglutathione lyase activity
ETL58_09965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ETL58_09970	COG1388	LysM domain
ETL58_09975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETL58_09980	COG4224	UPF0291 protein
ETL58_09985	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ETL58_09995	COG3763	UPF0154 protein
ETL58_10005	COG0785	Cytochrome C biogenesis protein
ETL58_10010	COG2201	protein-glutamate methylesterase activity
ETL58_10015	COG4846	Membrane protein involved in cytochrome C biogenesis
ETL58_10025	COG0071	Belongs to the small heat shock protein (HSP20) family
ETL58_10040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ETL58_10045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_10065	COG0824	Thioesterase
ETL58_10075	COG4841	protein insertion into membrane
ETL58_10080	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ETL58_10085	COG1832	CoA-binding protein
ETL58_10090	COG0187	DNA topoisomerase II activity
ETL58_10095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETL58_10105	COG1115	amino acid carrier protein
ETL58_10110	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ETL58_10120	COG5520	Belongs to the glycosyl hydrolase 30 family
ETL58_10125	COG3507	Belongs to the glycosyl hydrolase 43 family
ETL58_10135	COG2246	polysaccharide biosynthetic process
ETL58_10140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETL58_10145	COG0586	Pfam SNARE associated Golgi protein
ETL58_10150	COG2404	hydrolase activity, acting on ester bonds
ETL58_10155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETL58_10160	COG1024	Enoyl-CoA hydratase
ETL58_10165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETL58_10170	COG0511	ligase activity, forming carbon-carbon bonds
ETL58_10175	COG0439	Biotin carboxylase
ETL58_10180	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_10185	COG1960	acyl-CoA dehydrogenase activity
ETL58_10195	COG1649	PFAM Uncharacterised BCR, COG1649
ETL58_10205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_10205	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ETL58_10210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_10215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_10220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_10225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_10230	COG2027	D-alanyl-D-alanine carboxypeptidase
ETL58_10235	COG2017	converts alpha-aldose to the beta-anomer
ETL58_10240	COG0534	Mate efflux family protein
ETL58_10255	COG0582	viral genome integration into host DNA
ETL58_10260	COG0166	Belongs to the GPI family
ETL58_10265	COG0405	Gamma-glutamyltransferase
ETL58_10270	COG0583	DNA-binding transcription factor activity
ETL58_10275	COG0604	alcohol dehydrogenase
ETL58_10280	COG0493	'glutamate synthase
ETL58_10285	COG0069	glutamate synthase activity
ETL58_10285	COG0070	glutamate synthase
ETL58_10285	COG0067	glutamate synthase
ETL58_10290	COG0583	DNA-binding transcription factor activity
ETL58_10295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETL58_10300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETL58_10310	COG0300	oxidoreductase activity
ETL58_10315	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ETL58_10325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_10340	COG2814	Major facilitator Superfamily
ETL58_10345	COG1070	Carbohydrate kinase
ETL58_10350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETL58_10355	COG0243	molybdopterin cofactor binding
ETL58_10385	COG0840	transmembrane signaling receptor activity
ETL58_10385	COG5278	phosphoserine phosphatase activity
ETL58_10390	COG2368	4-hydroxyphenylacetate
ETL58_10395	COG4305	rare lipoprotein A
ETL58_10400	COG3619	membrane
ETL58_10405	COG3866	Pectate lyase
ETL58_10410	COG2135	peptidase activity
ETL58_10435	COG0456	acetyltransferase
ETL58_10455	COG2720	vancomycin resistance protein
ETL58_10465	COG3655	Transcriptional regulator
ETL58_10470	COG3739	integral membrane protein
ETL58_10475	COG0583	DNA-binding transcription factor activity
ETL58_10480	COG0697	spore germination
ETL58_10490	COG0693	protein deglycase activity
ETL58_10495	COG2367	Beta-lactamase
ETL58_10515	COG0574	Belongs to the PEP-utilizing enzyme family
ETL58_10515	COG3848	Pyruvate phosphate dikinase
ETL58_10520	COG0726	polysaccharide deacetylase
ETL58_10530	COG2314	TM2 domain
ETL58_10535	COG1396	sequence-specific DNA binding
ETL58_10580	COG2723	6-phospho-beta-galactosidase activity
ETL58_10595	COG0395	ABC-type sugar transport system, permease component
ETL58_10600	COG1175	transmembrane transport
ETL58_10610	COG1940	carbohydrate kinase activity
ETL58_10625	COG5444	nuclease activity
ETL58_10630	COG4282	regulation of fungal-type cell wall biogenesis
ETL58_10635	COG1231	oxidoreductase activity
ETL58_10640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETL58_10645	COG2207	Transcriptional regulator
ETL58_10645	COG0662	Cupin 2, conserved barrel domain protein
ETL58_10650	COG0456	acetyltransferase
ETL58_10655	COG1309	transcriptional regulator
ETL58_10660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_10665	COG3708	Transcriptional regulator
ETL58_10670	COG2378	regulation of single-species biofilm formation
ETL58_10680	COG0640	Transcriptional regulator
ETL58_10685	COG0741	lytic transglycosylase activity
ETL58_10690	COG2322	membrane
ETL58_10705	COG1619	proteins homologs of microcin C7 resistance protein MccF
ETL58_10710	COG3239	Fatty acid desaturase
ETL58_10715	COG4585	Histidine kinase
ETL58_10720	COG2197	response regulator
ETL58_10725	COG1388	LysM domain
ETL58_10725	COG3584	3D domain protein
ETL58_10730	COG0514	ATP-dependent DNA helicase (RecQ)
ETL58_10745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ETL58_10750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETL58_10765	COG0071	Belongs to the small heat shock protein (HSP20) family
ETL58_10790	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_10795	COG1657	PFAM Prenyltransferase squalene oxidase
ETL58_10800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETL58_10805	COG0733	neurotransmitter:sodium symporter activity
ETL58_10810	COG0385	Bile acid
ETL58_10815	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETL58_10820	COG0567	Dehydrogenase, E1 component
ETL58_10825	COG4548	von Willebrand factor, type A
ETL58_10830	COG0714	Associated with various cellular activities
ETL58_10835	COG2032	superoxide dismutase activity
ETL58_10840	COG1388	LysM domain
ETL58_10840	COG0791	NLP P60 protein
ETL58_10845	COG1819	glycosyl
ETL58_10850	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETL58_10855	COG0534	Mate efflux family protein
ETL58_10860	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_10865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETL58_10870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETL58_10880	COG2962	Rard protein
ETL58_10895	COG2610	gluconate transmembrane transporter activity
ETL58_10900	COG1942	4-Oxalocrotonate Tautomerase
ETL58_10905	COG1733	regulation of RNA biosynthetic process
ETL58_10910	COG0778	Nitroreductase
ETL58_10915	COG0400	carboxylic ester hydrolase activity
ETL58_10920	COG0346	lactoylglutathione lyase activity
ETL58_10930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETL58_10935	COG0793	Belongs to the peptidase S41A family
ETL58_10935	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_10940	COG2226	methyltransferase
ETL58_10950	COG1876	peptidase activity
ETL58_10955	COG0813	purine-nucleoside phosphorylase activity
ETL58_10970	COG0671	phosphoesterase, PA-phosphatase related
ETL58_10995	COG4479	Belongs to the UPF0346 family
ETL58_11005	COG1509	lysine 2,3-aminomutase activity
ETL58_11010	COG0456	acetyltransferase
ETL58_11015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETL58_11020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ETL58_11025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETL58_11030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETL58_11045	COG0456	acetyltransferase
ETL58_11050	COG0463	Glycosyl transferase, family 2
ETL58_11065	COG4641	Protein conserved in bacteria
ETL58_11070	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
ETL58_11075	COG1086	Polysaccharide biosynthesis protein
ETL58_11080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETL58_11085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETL58_11090	COG1846	Transcriptional regulator
ETL58_11095	COG0534	Mate efflux family protein
ETL58_11105	COG4698	Protein conserved in bacteria
ETL58_11110	COG2755	lipolytic protein G-D-S-L family
ETL58_11115	COG1999	signal sequence binding
ETL58_11125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETL58_11130	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ETL58_11135	COG1272	protein, Hemolysin III
ETL58_11140	COG0204	Acyl-transferase
ETL58_11145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETL58_11150	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ETL58_11155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETL58_11165	COG2521	methyltransferase
ETL58_11165	COG2136	Putative SAM-dependent methyltransferase
ETL58_11175	COG0129	dihydroxy-acid dehydratase activity
ETL58_11180	COG1413	lyase activity
ETL58_11185	COG1418	mRNA catabolic process
ETL58_11190	COG0386	Belongs to the glutathione peroxidase family
ETL58_11195	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ETL58_11200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETL58_11210	COG1278	Cold shock
ETL58_11230	COG0328	RNA-DNA hybrid ribonuclease activity
ETL58_11235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ETL58_11240	COG0328	RNA-DNA hybrid ribonuclease activity
ETL58_11250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETL58_11265	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ETL58_11275	COG1755	Isoprenylcysteine carboxyl methyltransferase
ETL58_11280	COG3424	synthase
ETL58_11285	COG2233	PERMEase
ETL58_11290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETL58_11295	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ETL58_11305	COG0800	Aldolase
ETL58_11310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETL58_11315	COG1609	Transcriptional regulator
ETL58_11320	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ETL58_11325	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_11330	COG1199	ATP-dependent helicase activity
ETL58_11345	COG0116	Belongs to the methyltransferase superfamily
ETL58_11360	COG4474	Belongs to the UPF0398 family
ETL58_11375	COG3359	exonuclease
ETL58_11380	COG1205	dead DEAH box helicase
ETL58_11380	COG1111	helicase
ETL58_11385	COG2190	(PTS) system
ETL58_11390	COG0071	Belongs to the small heat shock protein (HSP20) family
ETL58_11425	COG3331	DNA recombination
ETL58_11430	COG4499	WXG100 protein secretion system (Wss), protein YukC
ETL58_11430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETL58_11440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ETL58_11445	COG3935	DnaD domain protein
ETL58_11450	COG0017	Asparaginyl-tRNA synthetase
ETL58_11455	COG0436	Aminotransferase
ETL58_11460	COG5353	protein conserved in bacteria
ETL58_11470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ETL58_11470	COG1199	ATP-dependent helicase activity
ETL58_11475	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ETL58_11480	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ETL58_11485	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ETL58_11490	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ETL58_11490	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ETL58_11495	COG0617	tRNA 3'-terminal CCA addition
ETL58_11500	COG0438	transferase activity, transferring glycosyl groups
ETL58_11505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETL58_11510	COG1803	Methylglyoxal synthase
ETL58_11515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ETL58_11520	COG1694	Mazg nucleotide pyrophosphohydrolase
ETL58_11525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_11535	COG4347	Protein of unknown function (DUF1405)
ETL58_11540	COG2010	Cytochrome c
ETL58_11540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETL58_11545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETL58_11550	COG0723	plastoquinol--plastocyanin reductase activity
ETL58_11560	COG5582	Belongs to the UPF0302 family
ETL58_11565	COG0457	Tetratricopeptide repeat
ETL58_11570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ETL58_11575	COG0287	Prephenate dehydrogenase
ETL58_11580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ETL58_11590	COG0133	tryptophan synthase activity
ETL58_11595	COG0135	phosphoribosylanthranilate isomerase activity
ETL58_11605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ETL58_11610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETL58_11615	COG4401	Chorismate mutase type I
ETL58_11620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ETL58_11625	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ETL58_11630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ETL58_11635	COG0105	UTP biosynthetic process
ETL58_11640	COG0142	geranyltranstransferase activity
ETL58_11645	COG2226	methyltransferase
ETL58_11650	COG0142	geranyltranstransferase activity
ETL58_11660	COG0302	gtp cyclohydrolase
ETL58_11665	COG0776	regulation of translation
ETL58_11670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ETL58_11685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ETL58_11690	COG1160	GTP binding
ETL58_11715	COG1304	FMN binding
ETL58_11720	COG0539	negative regulation of cytoplasmic translation
ETL58_11725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ETL58_11735	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ETL58_11740	COG2959	enzyme of heme biosynthesis
ETL58_11745	COG3773	Cell wall hydrolase
ETL58_11745	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_11750	COG2339	peptidase activity
ETL58_11755	COG0492	ferredoxin-NADP+ reductase activity
ETL58_11760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETL58_11765	COG4862	establishment of competence for transformation
ETL58_11770	COG1408	metallophosphoesterase
ETL58_11780	COG1388	LysM domain
ETL58_11785	COG1266	CAAX protease self-immunity
ETL58_11790	COG0514	ATP-dependent DNA helicase (RecQ)
ETL58_11795	COG4955	Helix-turn-helix domain
ETL58_11800	COG1141	Ferredoxin
ETL58_11805	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ETL58_11810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETL58_11815	COG0710	3-dehydroquinate dehydratase activity
ETL58_11825	COG1595	DNA-templated transcription, initiation
ETL58_11830	COG5002	protein histidine kinase activity
ETL58_11835	COG0745	RESPONSE REGULATOR receiver
ETL58_11840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETL58_11845	COG1333	cytochrome c biogenesis protein
ETL58_11850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_11855	COG1187	pseudouridine synthase activity
ETL58_11860	COG0700	Nucleoside recognition
ETL58_11865	COG2715	membrane protein required for spore maturation
ETL58_11870	COG1686	Belongs to the peptidase S11 family
ETL58_11880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ETL58_11885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ETL58_11890	COG1547	Domain of unknown function (DUF309)
ETL58_11895	COG0456	acetyltransferase
ETL58_11900	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ETL58_11905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ETL58_11905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ETL58_11910	COG0307	riboflavin synthase, alpha
ETL58_11915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETL58_11915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETL58_11925	COG0681	Belongs to the peptidase S26 family
ETL58_11935	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
ETL58_11955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETL58_11965	COG4086	secreted protein
ETL58_11970	COG0019	diaminopimelate decarboxylase activity
ETL58_11975	COG0697	spore germination
ETL58_11990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETL58_12010	COG1191	sigma factor activity
ETL58_12015	COG2172	sigma factor antagonist activity
ETL58_12020	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_12025	COG1686	Belongs to the peptidase S11 family
ETL58_12030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ETL58_12035	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ETL58_12040	COG4974	Belongs to the 'phage' integrase family
ETL58_12050	COG0735	belongs to the Fur family
ETL58_12055	COG1300	Membrane
ETL58_12065	COG0281	malic enzyme
ETL58_12070	COG1757	Na H antiporter
ETL58_12075	COG1027	Aspartate ammonia-lyase
ETL58_12080	COG0252	asparaginase activity
ETL58_12085	COG1396	sequence-specific DNA binding
ETL58_12090	COG1379	DNA repair
ETL58_12095	COG0494	nUDIX hydrolase
ETL58_12105	COG0667	Aldo Keto reductase
ETL58_12115	COG1073	alpha beta
ETL58_12125	COG4918	Iron-sulphur cluster biosynthesis
ETL58_12130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ETL58_12130	COG0456	acetyltransferase
ETL58_12135	COG2329	Antibiotic biosynthesis monooxygenase
ETL58_12140	COG0456	acetyltransferase
ETL58_12150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETL58_12160	COG2211	Major facilitator Superfamily
ETL58_12165	COG0346	lactoylglutathione lyase activity
ETL58_12170	COG1072	(Pantothenic acid kinase))
ETL58_12175	COG3048	D-serine ammonia-lyase activity
ETL58_12180	COG0300	oxidoreductase activity
ETL58_12185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_12190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETL58_12195	COG4187	Peptidase family M20/M25/M40
ETL58_12200	COG1902	pentaerythritol trinitrate reductase activity
ETL58_12205	COG0596	Alpha beta hydrolase
ETL58_12215	COG1234	tRNA 3'-trailer cleavage
ETL58_12220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ETL58_12225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETL58_12230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETL58_12240	COG0706	membrane insertase activity
ETL58_12245	COG3361	conserved protein (COG2071)
ETL58_12250	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETL58_12255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETL58_12260	COG0346	lactoylglutathione lyase activity
ETL58_12265	COG1376	ErfK ybiS ycfS ynhG family protein
ETL58_12270	COG4129	membrane
ETL58_12275	COG1126	abc transporter atp-binding protein
ETL58_12280	COG0765	amino acid transport
ETL58_12285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_12295	COG1597	lipid kinase activity
ETL58_12300	COG2814	Major facilitator Superfamily
ETL58_12305	COG0789	Transcriptional regulator
ETL58_12305	COG4978	Transcriptional regulator
ETL58_12310	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETL58_12315	COG0022	dehydrogenase e1 component
ETL58_12320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETL58_12325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETL58_12330	COG3426	butyrate kinase activity
ETL58_12335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETL58_12340	COG0280	phosphate acetyltransferase
ETL58_12345	COG3290	protein histidine kinase activity
ETL58_12345	COG3829	transcription factor binding
ETL58_12355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ETL58_12360	COG2079	MmgE PrpD family protein
ETL58_12365	COG0372	Belongs to the citrate synthase family
ETL58_12370	COG1960	acyl-CoA dehydrogenase activity
ETL58_12375	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETL58_12380	COG0183	Belongs to the thiolase family
ETL58_12385	COG0584	glycerophosphoryl diester phosphodiesterase
ETL58_12390	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_12405	COG1902	pentaerythritol trinitrate reductase activity
ETL58_12410	COG0745	RESPONSE REGULATOR receiver
ETL58_12415	COG0750	zinc metalloprotease
ETL58_12420	COG0497	DNA recombination
ETL58_12425	COG1438	arginine binding
ETL58_12430	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ETL58_12435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ETL58_12440	COG0142	geranyltranstransferase activity
ETL58_12445	COG1722	exodeoxyribonuclease VII activity
ETL58_12450	COG1570	exodeoxyribonuclease VII activity
ETL58_12455	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ETL58_12460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETL58_12465	COG1302	Protein conserved in bacteria
ETL58_12470	COG0439	Biotin carboxylase
ETL58_12475	COG0511	ligase activity, forming carbon-carbon bonds
ETL58_12515	COG3854	ATPases associated with a variety of cellular activities
ETL58_12525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ETL58_12530	COG0006	proline dipeptidase activity
ETL58_12535	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ETL58_12545	COG3872	metal-dependent enzyme
ETL58_12555	COG1752	Esterase of the alpha-beta hydrolase superfamily
ETL58_12560	COG1321	iron dependent repressor
ETL58_12565	COG0095	Lipoate-protein ligase
ETL58_12570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETL58_12575	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETL58_12580	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETL58_12585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ETL58_12590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETL58_12605	COG1396	sequence-specific DNA binding
ETL58_12615	COG0681	Belongs to the peptidase S26 family
ETL58_12640	COG4940	Competence protein ComGF
ETL58_12650	COG4970	Tfp pilus assembly protein FimT
ETL58_12655	COG4537	Required for transformation and DNA binding
ETL58_12660	COG1459	type II secretion system
ETL58_12665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETL58_12675	COG0598	Magnesium transport protein CorA
ETL58_12680	COG1253	flavin adenine dinucleotide binding
ETL58_12685	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_12695	COG1393	Belongs to the ArsC family
ETL58_12705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_12715	COG0011	TIGRFAM Protein of
ETL58_12725	COG2866	Carboxypeptidase
ETL58_12730	COG1368	sulfuric ester hydrolase activity
ETL58_12735	COG1940	carbohydrate kinase activity
ETL58_12740	COG4483	Protein conserved in bacteria
ETL58_12745	COG0457	Tetratricopeptide repeat
ETL58_12745	COG0705	Rhomboid family
ETL58_12755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ETL58_12760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ETL58_12765	COG0438	transferase activity, transferring glycosyl groups
ETL58_12780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETL58_12785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETL58_12790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETL58_12795	COG0581	inorganic phosphate transmembrane transporter activity
ETL58_12800	COG0573	inorganic phosphate transmembrane transporter activity
ETL58_12805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ETL58_12815	COG0477	Major facilitator Superfamily
ETL58_12820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETL58_12825	COG2839	Protein conserved in bacteria
ETL58_12830	COG5521	maltodextrose utilization protein MalA
ETL58_12835	COG1388	LysM domain
ETL58_12840	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ETL58_12845	COG4709	membrane
ETL58_12850	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
ETL58_12855	COG0735	belongs to the Fur family
ETL58_12860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_12870	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ETL58_12875	COG0513	Belongs to the DEAD box helicase family
ETL58_12885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ETL58_12890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ETL58_12895	COG2384	SAM-dependent methyltransferase
ETL58_12900	COG2010	Cytochrome c
ETL58_12910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETL58_12915	COG0358	DNA primase activity
ETL58_12920	COG1671	Belongs to the UPF0178 family
ETL58_12925	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ETL58_12930	COG0517	IMP dehydrogenase activity
ETL58_12935	COG0751	glycine-tRNA ligase activity
ETL58_12940	COG0752	glycyl-tRNA synthetase alpha subunit
ETL58_12945	COG1381	Involved in DNA repair and RecF pathway recombination
ETL58_12955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ETL58_12960	COG0295	cytidine deaminase activity
ETL58_12965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ETL58_12970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ETL58_12975	COG1480	7TM receptor with intracellular HD hydrolase
ETL58_12980	COG1702	phosphate starvation-inducible protein PhoH
ETL58_12985	COG0561	phosphatase activity
ETL58_13000	COG4864	UPF0365 protein
ETL58_13005	COG1030	water channel activity
ETL58_13010	COG1610	YqeY-like protein
ETL58_13015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ETL58_13020	COG1283	sodium-dependent phosphate transmembrane transporter activity
ETL58_13025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETL58_13030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETL58_13035	COG2264	protein methyltransferase activity
ETL58_13040	COG0484	heat shock protein binding
ETL58_13045	COG0443	Heat shock 70 kDa protein
ETL58_13050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ETL58_13055	COG1420	regulation of RNA biosynthetic process
ETL58_13060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETL58_13065	COG0481	GTPase activity
ETL58_13075	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_13080	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ETL58_13085	COG0268	Binds directly to 16S ribosomal RNA
ETL58_13090	COG1466	dna polymerase III delta subunit
ETL58_13105	COG2333	competence protein COMEC
ETL58_13105	COG0658	competence protein
ETL58_13110	COG2131	deaminase
ETL58_13115	COG1555	photosystem II stabilization
ETL58_13115	COG1596	polysaccharide export
ETL58_13120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETL58_13125	COG2226	methyltransferase
ETL58_13130	COG0799	negative regulation of ribosome biogenesis
ETL58_13135	COG1713	HD superfamily hydrolase involved in NAD metabolism
ETL58_13140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ETL58_13145	COG1534	Rna-binding protein
ETL58_13150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETL58_13155	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETL58_13160	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ETL58_13170	COG2755	lipolytic protein G-D-S-L family
ETL58_13175	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_13175	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETL58_13180	COG0398	Pfam SNARE associated Golgi protein
ETL58_13185	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ETL58_13195	COG3209	COG3209 Rhs family protein
ETL58_13205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETL58_13215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETL58_13220	COG0798	PFAM Bile acid sodium symporter
ETL58_13225	COG0346	lactoylglutathione lyase activity
ETL58_13230	COG0640	Transcriptional regulator
ETL58_13235	COG3403	YqcI/YcgG family
ETL58_13240	COG0457	Tetratricopeptide repeat
ETL58_13255	COG5444	nuclease activity
ETL58_13260	COG4282	regulation of fungal-type cell wall biogenesis
ETL58_13290	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETL58_13290	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_13295	COG4824	toxin secretion phage lysis holin
ETL58_13325	COG3778	Protein conserved in bacteria
ETL58_13330	COG3299	homolog of phage Mu protein gp47
ETL58_13335	COG3628	GPW Gp25 family protein
ETL58_13345	COG4193	domain, Protein
ETL58_13350	COG1652	LysM domain
ETL58_13355	COG5280	Phage tail tape measure protein TP901
ETL58_13355	COG3953	SLT domain
ETL58_13420	COG4653	Phage capsid family
ETL58_13425	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ETL58_13435	COG2369	cell adhesion
ETL58_13440	COG5518	Phage portal protein
ETL58_13445	COG1783	phage Terminase large subunit
ETL58_13450	COG5484	DNA packaging
ETL58_13465	COG3677	Transposase
ETL58_13485	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ETL58_13495	COG1484	DNA-dependent DNA replication
ETL58_13500	COG3935	DnaD domain protein
ETL58_13505	COG3723	Recombinational DNA repair protein, rece pathway
ETL58_13510	COG5377	YqaJ viral recombinase family
ETL58_13545	COG3620	sequence-specific DNA binding
ETL58_13555	COG0563	adenylate kinase activity
ETL58_13560	COG2856	Zn peptidase
ETL58_13585	COG3223	Belongs to the PsiE family
ETL58_13590	COG5002	protein histidine kinase activity
ETL58_13590	COG0642	Histidine kinase
ETL58_13595	COG0745	RESPONSE REGULATOR receiver
ETL58_13600	COG2311	Membrane
ETL58_13610	COG0454	-acetyltransferase
ETL58_13615	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETL58_13625	COG0730	response to heat
ETL58_13630	COG0425	Belongs to the sulfur carrier protein TusA family
ETL58_13635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETL58_13635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_13645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETL58_13645	COG0425	Belongs to the sulfur carrier protein TusA family
ETL58_13655	COG2210	Belongs to the sulfur carrier protein TusA family
ETL58_13660	COG1937	Protein conserved in bacteria
ETL58_13675	COG0662	Cupin 2, conserved barrel domain protein
ETL58_13690	COG0789	Transcriptional regulator
ETL58_13690	COG4978	Transcriptional regulator
ETL58_13695	COG2814	Major facilitator Superfamily
ETL58_13700	COG0456	acetyltransferase
ETL58_13705	COG1253	flavin adenine dinucleotide binding
ETL58_13715	COG0697	spore germination
ETL58_13720	COG0583	DNA-binding transcription factor activity
ETL58_13725	COG2072	flavoprotein involved in K transport
ETL58_13730	COG1230	cation diffusion facilitator family transporter
ETL58_13735	COG1942	4-Oxalocrotonate Tautomerase
ETL58_13740	COG0583	DNA-binding transcription factor activity
ETL58_13750	COG1114	Component of the transport system for branched-chain amino acids
ETL58_13755	COG1687	branched-chain amino acid
ETL58_13760	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ETL58_13765	COG1522	sequence-specific DNA binding
ETL58_13775	COG2124	cytochrome p450
ETL58_13780	COG1335	isochorismatase
ETL58_13795	COG2318	DinB family
ETL58_13805	COG2070	2-Nitropropane dioxygenase
ETL58_13840	COG3443	Belongs to the bacterial solute-binding protein 9 family
ETL58_13845	COG1595	DNA-templated transcription, initiation
ETL58_13850	COG0667	Aldo Keto reductase
ETL58_13855	COG2851	Citrate transporter
ETL58_13860	COG0583	DNA-binding transcription factor activity
ETL58_13865	COG2828	Protein conserved in bacteria
ETL58_13870	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_13875	COG5566	PFAM Mor transcription activator
ETL58_13880	COG0596	Alpha beta hydrolase
ETL58_13885	COG4991	sh3 domain protein
ETL58_13890	COG4991	sh3 domain protein
ETL58_13900	COG0346	lactoylglutathione lyase activity
ETL58_13910	COG5577	PFAM Coat F domain
ETL58_13915	COG1063	alcohol dehydrogenase
ETL58_13925	COG5577	PFAM Coat F domain
ETL58_13930	COG0789	Transcriptional regulator
ETL58_13940	COG1064	alcohol dehydrogenase
ETL58_13945	COG0693	protein deglycase activity
ETL58_13950	COG1621	beta-fructofuranosidase activity
ETL58_13955	COG3716	PTS system mannose fructose sorbose family IID component
ETL58_13960	COG3715	PTS system
ETL58_13965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_13970	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_13975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ETL58_13975	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ETL58_13985	COG1113	amino acid transport
ETL58_13990	COG1280	lysine exporter protein (LysE YggA)
ETL58_13995	COG1378	Sugar-specific transcriptional regulator TrmB
ETL58_14000	COG1595	DNA-templated transcription, initiation
ETL58_14010	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETL58_14010	COG2755	lipolytic protein G-D-S-L family
ETL58_14020	COG2124	cytochrome p450
ETL58_14020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETL58_14025	COG1309	transcriptional regulator
ETL58_14030	COG2226	methyltransferase
ETL58_14045	COG2116	formate transmembrane transporter activity
ETL58_14050	COG5609	conserved protein (DUF2294)
ETL58_14055	COG3383	formate dehydrogenase (NAD+) activity
ETL58_14060	COG2427	Protein of unknown function (DUF1641)
ETL58_14070	COG0626	cystathionine gamma-synthase activity
ETL58_14075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETL58_14080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ETL58_14085	COG2226	methyltransferase
ETL58_14100	COG0768	penicillin binding
ETL58_14105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ETL58_14110	COG0572	uridine kinase
ETL58_14130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETL58_14135	COG3906	Belongs to the UPF0473 family
ETL58_14140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ETL58_14145	COG4472	Bacterial protein of unknown function (DUF965)
ETL58_14150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ETL58_14155	COG0628	permease
ETL58_14160	COG1126	abc transporter atp-binding protein
ETL58_14165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_14170	COG0765	amino acid transport
ETL58_14175	COG0765	amino acid transport
ETL58_14190	COG3881	PFAM PRC-barrel domain
ETL58_14195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETL58_14200	COG0457	Tetratricopeptide repeat
ETL58_14205	COG0482	sulfurtransferase activity
ETL58_14210	COG1104	cysteine desulfurase activity
ETL58_14215	COG1959	2 iron, 2 sulfur cluster binding
ETL58_14220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ETL58_14225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ETL58_14235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ETL58_14240	COG0124	histidyl-tRNA synthetase
ETL58_14250	COG3103	Sh3 type 3 domain protein
ETL58_14250	COG4991	sh3 domain protein
ETL58_14250	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_14255	COG1490	D-aminoacyl-tRNA deacylase activity
ETL58_14260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ETL58_14265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETL58_14270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETL58_14270	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ETL58_14275	COG5416	Lipopolysaccharide assembly protein A domain
ETL58_14280	COG0490	domain, Protein
ETL58_14285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETL58_14285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETL58_14295	COG2244	polysaccharide biosynthetic process
ETL58_14300	COG2323	membrane
ETL58_14310	COG1862	Preprotein translocase
ETL58_14315	COG0343	queuine tRNA-ribosyltransferase activity
ETL58_14320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ETL58_14330	COG2255	four-way junction helicase activity
ETL58_14335	COG0632	four-way junction helicase activity
ETL58_14345	COG2814	Major facilitator Superfamily
ETL58_14350	COG0673	inositol 2-dehydrogenase activity
ETL58_14355	COG2112	serine threonine protein kinase
ETL58_14375	COG1115	amino acid carrier protein
ETL58_14380	COG0217	transcriptional regulatory protein
ETL58_14390	COG1388	LysM domain
ETL58_14395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ETL58_14400	COG0157	Belongs to the NadC ModD family
ETL58_14405	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ETL58_14410	COG1104	cysteine desulfurase activity
ETL58_14415	COG1827	regulation of RNA biosynthetic process
ETL58_14420	COG0077	Prephenate dehydratase
ETL58_14425	COG4492	Belongs to the UPF0735 family
ETL58_14430	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ETL58_14435	COG3290	protein histidine kinase activity
ETL58_14445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETL58_14450	COG2868	ribosomal protein
ETL58_14455	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ETL58_14460	COG1994	Peptidase M50
ETL58_14465	COG0739	heme binding
ETL58_14470	COG2894	cell division
ETL58_14475	COG0850	regulation of cytokinetic process
ETL58_14480	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ETL58_14485	COG1792	Involved in formation and maintenance of cell shape
ETL58_14490	COG1077	Cell shape determining protein MreB Mrl
ETL58_14495	COG2003	Belongs to the UPF0758 family
ETL58_14500	COG0424	maF-like protein
ETL58_14510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ETL58_14515	COG0285	dihydrofolate synthase activity
ETL58_14520	COG0525	valine-tRNA ligase activity
ETL58_14530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETL58_14535	COG1388	LysM domain
ETL58_14540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETL58_14545	COG0113	porphobilinogen synthase activity
ETL58_14550	COG1587	Uroporphyrinogen-III synthase
ETL58_14555	COG0181	hydroxymethylbilane synthase activity
ETL58_14560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETL58_14565	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ETL58_14575	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ETL58_14580	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ETL58_14585	COG0470	DNA polymerase III
ETL58_14585	COG1067	ATP-dependent peptidase activity
ETL58_14590	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ETL58_14595	COG0544	peptidyl-prolyl cis-trans isomerase activity
ETL58_14600	COG0457	Tetratricopeptide repeat
ETL58_14600	COG1477	protein flavinylation
ETL58_14605	COG0066	3-isopropylmalate dehydratase activity
ETL58_14610	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ETL58_14615	COG0473	3-isopropylmalate dehydrogenase activity
ETL58_14620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETL58_14625	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ETL58_14630	COG0440	acetolactate synthase activity
ETL58_14635	COG0028	Belongs to the TPP enzyme family
ETL58_14645	COG0454	-acetyltransferase
ETL58_14655	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
ETL58_14665	COG0622	Phosphoesterase
ETL58_14670	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ETL58_14675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ETL58_14680	COG5401	PFAM Sporulation and spore germination
ETL58_14685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ETL58_14690	COG1846	Transcriptional regulator
ETL58_14695	COG2197	response regulator
ETL58_14700	COG0824	Thioesterase
ETL58_14705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETL58_14710	COG1053	succinate dehydrogenase
ETL58_14715	COG2009	succinate dehydrogenase
ETL58_14720	COG1719	4-vinyl reductase, 4VR
ETL58_14725	COG0527	aspartate kinase activity
ETL58_14735	COG0322	excinuclease ABC activity
ETL58_14740	COG3118	belongs to the thioredoxin family
ETL58_14750	COG3534	alpha-L-arabinofuranosidase
ETL58_14755	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ETL58_14760	COG2086	electron transfer activity
ETL58_14765	COG1024	Enoyl-CoA hydratase
ETL58_14770	COG1309	transcriptional regulator
ETL58_14775	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_14780	COG3766	membrane
ETL58_14785	COG1193	negative regulation of DNA recombination
ETL58_14790	COG1796	DNA polymerase
ETL58_14790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETL58_14795	COG1286	toxin biosynthetic process
ETL58_14800	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ETL58_14805	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ETL58_14810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETL58_14810	COG0072	phenylalanine-tRNA ligase activity
ETL58_14815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ETL58_14825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETL58_14835	COG3835	regulator
ETL58_14840	COG0277	FAD linked oxidase domain protein
ETL58_14845	COG0247	lactate metabolic process
ETL58_14850	COG0346	lactoylglutathione lyase activity
ETL58_14860	COG1966	Carbon starvation protein
ETL58_14865	COG3534	alpha-L-arabinofuranosidase
ETL58_14870	COG0395	ABC-type sugar transport system, permease component
ETL58_14875	COG1175	transmembrane transport
ETL58_14880	COG1653	transport
ETL58_14885	COG0371	Dehydrogenase
ETL58_14890	COG0647	UMP catabolic process
ETL58_14895	COG0235	Class ii aldolase
ETL58_14900	COG1069	ribulokinase activity
ETL58_14905	COG2160	L-arabinose isomerase activity
ETL58_14910	COG3507	Belongs to the glycosyl hydrolase 43 family
ETL58_14915	COG1363	Peptidase, m42
ETL58_14925	COG3326	Membrane
ETL58_14930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ETL58_14935	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ETL58_14940	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ETL58_14950	COG1346	cytolysis
ETL58_14955	COG1380	Effector of murein hydrolase LrgA
ETL58_14960	COG3279	Response regulator of the LytR AlgR family
ETL58_14965	COG3275	phosphorelay sensor kinase activity
ETL58_14975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETL58_14985	COG0398	Pfam SNARE associated Golgi protein
ETL58_14990	COG1484	DNA-dependent DNA replication
ETL58_14995	COG3611	Membrane attachment protein
ETL58_15000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETL58_15005	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ETL58_15010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETL58_15015	COG1733	regulation of RNA biosynthetic process
ETL58_15020	COG2814	Major facilitator Superfamily
ETL58_15025	COG0656	L-ascorbic acid biosynthetic process
ETL58_15030	COG0237	dephospho-CoA kinase activity
ETL58_15035	COG1971	Probably functions as a manganese efflux pump
ETL58_15040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ETL58_15045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETL58_15045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETL58_15050	COG5002	protein histidine kinase activity
ETL58_15055	COG0745	RESPONSE REGULATOR receiver
ETL58_15060	COG0039	L-malate dehydrogenase activity
ETL58_15065	COG0538	isocitrate dehydrogenase activity
ETL58_15070	COG0372	Belongs to the citrate synthase family
ETL58_15075	COG2707	UPF0756 membrane protein
ETL58_15080	COG0628	permease
ETL58_15085	COG3030	protein affecting phage T7 exclusion by the F plasmid
ETL58_15090	COG0469	pyruvate kinase activity
ETL58_15095	COG0205	6-phosphofructokinase activity
ETL58_15100	COG0825	malonyl-CoA metabolic process
ETL58_15105	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ETL58_15110	COG0281	malic enzyme
ETL58_15115	COG0587	DNA-directed DNA polymerase activity
ETL58_15135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ETL58_15145	COG4109	DRTGG domain
ETL58_15150	COG0730	response to heat
ETL58_15155	COG1473	amidohydrolase
ETL58_15160	COG0196	riboflavin kinase activity
ETL58_15165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_15170	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ETL58_15175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_15180	COG1126	abc transporter atp-binding protein
ETL58_15185	COG0765	amino acid transport
ETL58_15190	COG0765	amino acid transport
ETL58_15195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_15200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_15205	COG0454	-acetyltransferase
ETL58_15210	COG0583	DNA-binding transcription factor activity
ETL58_15215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ETL58_15220	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_15230	COG0165	Argininosuccinate lyase
ETL58_15235	COG0137	argininosuccinate synthase activity
ETL58_15240	COG0521	Mo-molybdopterin cofactor biosynthetic process
ETL58_15245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ETL58_15255	COG0827	DNA restriction-modification system
ETL58_15260	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ETL58_15265	COG3874	Sporulation protein YtfJ
ETL58_15275	COG1714	RDD family
ETL58_15280	COG0616	signal peptide processing
ETL58_15285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETL58_15290	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ETL58_15295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETL58_15305	COG0301	tRNA thio-modification
ETL58_15310	COG1104	cysteine desulfurase activity
ETL58_15315	COG1114	Component of the transport system for branched-chain amino acids
ETL58_15320	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ETL58_15325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETL58_15330	COG1309	transcriptional regulator
ETL58_15335	COG1956	GAF domain-containing protein
ETL58_15340	COG2199	diguanylate cyclase activity
ETL58_15340	COG2203	Gaf domain
ETL58_15350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ETL58_15355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETL58_15360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETL58_15365	COG0454	-acetyltransferase
ETL58_15370	COG0517	IMP dehydrogenase activity
ETL58_15375	COG0123	including yeast histone deacetylase and acetoin utilization protein
ETL58_15380	COG1360	Flagellar Motor Protein
ETL58_15385	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ETL58_15390	COG1609	Transcriptional regulator
ETL58_15395	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETL58_15395	COG1605	Chorismate mutase
ETL58_15400	COG3118	belongs to the thioredoxin family
ETL58_15405	COG4980	gas vesicle protein
ETL58_15410	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ETL58_15415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ETL58_15420	COG1674	ftsk spoiiie
ETL58_15425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETL58_15430	COG4848	Belongs to the UPF0354 family
ETL58_15435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_15450	COG1363	Peptidase, m42
ETL58_15455	COG5584	Small secreted protein
ETL58_15460	COG0281	malic enzyme
ETL58_15465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_15470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ETL58_15480	COG0510	thiamine kinase activity
ETL58_15485	COG1523	belongs to the glycosyl hydrolase 13 family
ETL58_15490	COG1597	lipid kinase activity
ETL58_15500	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETL58_15505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETL58_15510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETL58_15515	COG2252	PERMEase
ETL58_15520	COG4473	ABC transporter
ETL58_15525	COG1131	(ABC) transporter
ETL58_15530	COG1349	DNA-binding transcription factor activity
ETL58_15535	COG1187	pseudouridine synthase activity
ETL58_15540	COG2244	polysaccharide biosynthetic process
ETL58_15545	COG2081	HI0933 family
ETL58_15550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ETL58_15560	COG5578	integral membrane protein
ETL58_15565	COG0673	inositol 2-dehydrogenase activity
ETL58_15570	COG1653	transport
ETL58_15575	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETL58_15580	COG4209	transmembrane transport
ETL58_15585	COG2207	Transcriptional regulator
ETL58_15590	COG1653	transport
ETL58_15595	COG0395	ABC-type sugar transport system, permease component
ETL58_15600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETL58_15605	COG2124	cytochrome p450
ETL58_15610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ETL58_15620	COG0156	8-amino-7-oxononanoate synthase activity
ETL58_15625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETL58_15635	COG1073	alpha beta
ETL58_15660	COG1486	melibiose metabolic process
ETL58_15665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETL58_15670	COG0495	leucyl-tRNA aminoacylation
ETL58_15680	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_15680	COG2202	Pas domain
ETL58_15685	COG2814	Major facilitator Superfamily
ETL58_15690	COG2433	Pfam Transposase IS66
ETL58_15695	COG0577	efflux transmembrane transporter activity
ETL58_15700	COG1136	(ABC) transporter
ETL58_15705	COG2205	protein histidine kinase activity
ETL58_15710	COG0745	RESPONSE REGULATOR receiver
ETL58_15715	COG0577	efflux transmembrane transporter activity
ETL58_15720	COG1136	(ABC) transporter
ETL58_15735	COG1131	(ABC) transporter
ETL58_15740	COG1725	Transcriptional regulator
ETL58_15755	COG1242	4 iron, 4 sulfur cluster binding
ETL58_15760	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ETL58_15770	COG2267	carboxylic ester hydrolase activity
ETL58_15775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ETL58_15780	COG1113	amino acid transport
ETL58_15785	COG0367	asparagine synthase
ETL58_15790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ETL58_15795	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ETL58_15805	COG1506	peptidase
ETL58_15810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETL58_15815	COG1116	anion transmembrane transporter activity
ETL58_15820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETL58_15825	COG0494	nUDIX hydrolase
ETL58_15830	COG4824	toxin secretion phage lysis holin
ETL58_15835	COG0783	Belongs to the Dps family
ETL58_15850	COG1854	S-ribosylhomocysteine lyase activity
ETL58_15855	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ETL58_15860	COG0288	reversible hydration of carbon dioxide
ETL58_15865	COG0254	rRNA binding
ETL58_15870	COG1271	oxidase subunit
ETL58_15875	COG1294	oxidase, subunit
ETL58_15885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETL58_15890	COG1321	iron dependent repressor
ETL58_15890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETL58_15895	COG1121	(ABC) transporter
ETL58_15900	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETL58_15905	COG4948	Mandelate Racemase Muconate Lactonizing
ETL58_15910	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_15915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ETL58_15920	COG0596	Alpha beta hydrolase
ETL58_15925	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ETL58_15930	COG1169	isochorismate synthase
ETL58_15940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETL58_15945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETL58_15950	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETL58_15955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETL58_15960	COG0438	transferase activity, transferring glycosyl groups
ETL58_15970	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETL58_15975	COG0438	transferase activity, transferring glycosyl groups
ETL58_15980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETL58_15985	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETL58_15990	COG0058	SHG alpha-glucan phosphorylase activity
ETL58_15995	COG0297	glycogen (starch) synthase activity
ETL58_16000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETL58_16005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETL58_16010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETL58_16135	COG3859	Proton-coupled thiamine transporter YuaJ
ETL58_16140	COG1247	-acetyltransferase
ETL58_16145	COG2268	Band 7 protein
ETL58_16150	COG1585	Membrane protein implicated in regulation of membrane protease activity
ETL58_16155	COG2318	DinB family
ETL58_16165	COG1454	alcohol dehydrogenase
ETL58_16175	COG1510	regulation of RNA biosynthetic process
ETL58_16185	COG0569	domain protein
ETL58_16190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETL58_16195	COG4682	membrane
ETL58_16200	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETL58_16205	COG0477	Major facilitator Superfamily
ETL58_16210	COG5553	Cysteine dioxygenase type I
ETL58_16220	COG1968	undecaprenyl-diphosphatase activity
ETL58_16225	COG0628	permease
ETL58_16230	COG0673	inositol 2-dehydrogenase activity
ETL58_16235	COG4806	L-rhamnose isomerase
ETL58_16240	COG3254	rhamnose metabolic process
ETL58_16245	COG1070	Carbohydrate kinase
ETL58_16250	COG1349	DNA-binding transcription factor activity
ETL58_16255	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_16255	COG3347	Dehydrogenase
ETL58_16265	COG0840	transmembrane signaling receptor activity
ETL58_16270	COG0840	transmembrane signaling receptor activity
ETL58_16275	COG0840	transmembrane signaling receptor activity
ETL58_16295	COG0432	Pfam Uncharacterised protein family UPF0047
ETL58_16305	COG0366	Alpha amylase catalytic
ETL58_16310	COG1253	flavin adenine dinucleotide binding
ETL58_16315	COG2738	Putative neutral zinc metallopeptidase
ETL58_16330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ETL58_16345	COG0166	Belongs to the GPI family
ETL58_16350	COG1979	alcohol dehydrogenase
ETL58_16355	COG1979	alcohol dehydrogenase
ETL58_16360	COG2155	Conserved Protein
ETL58_16365	COG1098	S1 RNA binding domain
ETL58_16370	COG0436	Aminotransferase
ETL58_16375	COG1522	sequence-specific DNA binding
ETL58_16380	COG2267	carboxylic ester hydrolase activity
ETL58_16390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ETL58_16395	COG2205	protein histidine kinase activity
ETL58_16405	COG5018	Exonuclease
ETL58_16415	COG2814	Major facilitator Superfamily
ETL58_16420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETL58_16425	COG3011	Protein conserved in bacteria
ETL58_16435	COG3290	protein histidine kinase activity
ETL58_16440	COG4565	transcriptional regulatory protein
ETL58_16465	COG3493	citrate carrier protein
ETL58_16475	COG2111	Na H antiporter
ETL58_16475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETL58_16480	COG2111	Na H antiporter
ETL58_16485	COG1006	Multisubunit Na H antiporter MnhC subunit
ETL58_16490	COG0651	ATP synthesis coupled electron transport
ETL58_16495	COG1863	multisubunit Na H antiporter MnhE subunit
ETL58_16500	COG2212	antiporter activity
ETL58_16505	COG1320	monovalent cation:proton antiporter activity
ETL58_16510	COG2050	protein possibly involved in aromatic compounds catabolism
ETL58_16515	COG2197	response regulator
ETL58_16520	COG4585	Histidine kinase
ETL58_16530	COG0142	geranyltranstransferase activity
ETL58_16550	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ETL58_16555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ETL58_16560	COG1335	isochorismatase
ETL58_16565	COG5506	Protein of unknown function (DUF1694)
ETL58_16580	COG0628	permease
ETL58_16595	COG1418	mRNA catabolic process
ETL58_16600	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_16610	COG1511	domain protein
ETL58_16615	COG0433	COG0433 Predicted ATPase
ETL58_16615	COG1674	ftsk spoiiie
ETL58_16620	COG4499	WXG100 protein secretion system (Wss), protein YukC
ETL58_16625	COG5417	Belongs to the EsaB family
ETL58_16630	COG4842	Belongs to the WXG100 family
ETL58_16640	COG2508	Transcriptional regulator
ETL58_16640	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ETL58_16645	COG0686	Belongs to the AlaDH PNT family
ETL58_16650	COG5634	Uncharacterized conserved protein (DUF2278)
ETL58_16655	COG3251	PFAM MbtH domain protein
ETL58_16660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_16665	COG1535	isochorismatase
ETL58_16665	COG3433	isochorismatase activity
ETL58_16670	COG1021	2,3-dihydroxybenzoate-AMP ligase
ETL58_16675	COG1169	isochorismate synthase
ETL58_16680	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_16685	COG2819	hydrolase of the alpha beta superfamily
ETL58_16690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETL58_16695	COG1268	BioY protein
ETL58_16700	COG2056	Na+-H+ antiporter family
ETL58_16705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ETL58_16710	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ETL58_16715	COG3584	3D domain protein
ETL58_16730	COG1252	NADH dehydrogenase
ETL58_16735	COG0492	ferredoxin-NADP+ reductase activity
ETL58_16745	COG0516	GMP reductase activity
ETL58_16750	COG2808	Putative FMN-binding domain
ETL58_16755	COG0456	acetyltransferase
ETL58_16760	COG0316	Belongs to the HesB IscA family
ETL58_16765	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ETL58_16770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETL58_16775	COG4844	belongs to the
ETL58_16780	COG1252	NADH dehydrogenase
ETL58_16785	COG4837	Protein of unknown function (DUF1462)
ETL58_16790	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ETL58_16795	COG0823	Involved in the tonB-independent uptake of proteins
ETL58_16795	COG1506	peptidase
ETL58_16795	COG4946	Tricorn protease homolog
ETL58_16800	COG0083	homoserine kinase activity
ETL58_16805	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETL58_16810	COG0460	homoserine dehydrogenase
ETL58_16820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETL58_16825	COG0647	UMP catabolic process
ETL58_16830	COG2445	Protein of unknown function DUF86
ETL58_16835	COG4470	Protein conserved in bacteria
ETL58_16845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ETL58_16850	COG0739	heme binding
ETL58_16860	COG3377	Domain of unknown function (DUF1805)
ETL58_16865	COG0737	Belongs to the 5'-nucleotidase family
ETL58_16870	COG0730	response to heat
ETL58_16875	COG1801	Protein of unknown function DUF72
ETL58_16885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETL58_16890	COG2508	Transcriptional regulator
ETL58_16895	COG2233	PERMEase
ETL58_16900	COG2233	PERMEase
ETL58_16905	COG3195	allantoin biosynthetic process
ETL58_16905	COG3648	Uricase
ETL58_16910	COG2351	hydroxyisourate hydrolase activity
ETL58_16920	COG2080	2 iron, 2 sulfur cluster binding
ETL58_16925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ETL58_16930	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ETL58_16935	COG2068	MobA-Related Protein
ETL58_16940	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ETL58_16945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ETL58_16950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETL58_16960	COG2356	endonuclease I
ETL58_16965	COG3842	ATPase activity
ETL58_16970	COG2188	Transcriptional regulator
ETL58_16975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETL58_16980	COG0395	ABC-type sugar transport system, permease component
ETL58_16985	COG1175	transmembrane transport
ETL58_16990	COG1653	transport
ETL58_16995	COG2222	sugar isomerase
ETL58_17000	COG0322	excinuclease ABC activity
ETL58_17005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETL58_17020	COG0346	lactoylglutathione lyase activity
ETL58_17025	COG0640	Transcriptional regulator
ETL58_17030	COG0719	Fe-S assembly protein
ETL58_17035	COG0822	iron-sulfur transferase activity
ETL58_17040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETL58_17045	COG0719	Fe-S assembly protein
ETL58_17050	COG0396	ATPase activity
ETL58_17065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ETL58_17070	COG1464	Belongs to the NlpA lipoprotein family
ETL58_17075	COG2011	ABC-type metal ion transport system permease component
ETL58_17080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ETL58_17090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_17095	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ETL58_17105	COG0509	glycine decarboxylation via glycine cleavage system
ETL58_17110	COG1393	Belongs to the ArsC family
ETL58_17115	COG1960	acyl-CoA dehydrogenase activity
ETL58_17120	COG0183	Belongs to the thiolase family
ETL58_17125	COG1024	Enoyl-CoA hydratase
ETL58_17125	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETL58_17135	COG0506	proline dehydrogenase activity
ETL58_17145	COG5577	PFAM Coat F domain
ETL58_17150	COG1846	Transcriptional regulator
ETL58_17155	COG0477	Major facilitator Superfamily
ETL58_17160	COG1942	4-Oxalocrotonate Tautomerase
ETL58_17165	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_17170	COG0583	DNA-binding transcription factor activity
ETL58_17180	COG1120	ATPase activity
ETL58_17195	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_17200	COG0783	Belongs to the Dps family
ETL58_17205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETL58_17210	COG0745	RESPONSE REGULATOR receiver
ETL58_17215	COG2770	Histidine kinase
ETL58_17215	COG2205	protein histidine kinase activity
ETL58_17225	COG1309	transcriptional regulator
ETL58_17230	COG0114	fumarate hydratase activity
ETL58_17240	COG0697	spore germination
ETL58_17245	COG0814	amino acid
ETL58_17255	COG2197	response regulator
ETL58_17260	COG4585	Histidine kinase
ETL58_17265	COG4758	membrane
ETL58_17270	COG3595	metallopeptidase activity
ETL58_17275	COG1842	Phage shock protein A
ETL58_17280	COG4758	membrane
ETL58_17285	COG2814	Major facilitator Superfamily
ETL58_17290	COG2096	Adenosyltransferase
ETL58_17295	COG1120	ATPase activity
ETL58_17300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_17305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_17310	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_17315	COG3386	PFAM SMP-30 Gluconolaconase
ETL58_17320	COG2205	protein histidine kinase activity
ETL58_17325	COG0745	RESPONSE REGULATOR receiver
ETL58_17335	COG1191	sigma factor activity
ETL58_17345	COG2140	Oxalate decarboxylase
ETL58_17355	COG0577	efflux transmembrane transporter activity
ETL58_17360	COG1136	(ABC) transporter
ETL58_17365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETL58_17370	COG1120	ATPase activity
ETL58_17375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_17380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_17385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_17395	COG0531	amino acid
ETL58_17410	COG1988	membrane-bound metal-dependent
ETL58_17415	COG1368	sulfuric ester hydrolase activity
ETL58_17420	COG1910	domain protein
ETL58_17425	COG0725	ABC transporter, periplasmic molybdate-binding protein
ETL58_17430	COG4149	molybdate abc transporter
ETL58_17435	COG0656	L-ascorbic acid biosynthetic process
ETL58_17445	COG0025	NhaP-type Na H and K H
ETL58_17450	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETL58_17455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETL58_17460	COG3973	AAA domain
ETL58_17465	COG2860	membrane
ETL58_17470	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ETL58_17475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ETL58_17480	COG2217	Heavy metal translocating P-type atpase
ETL58_17485	COG2217	Heavy metal translocating P-type atpase
ETL58_17490	COG2608	mercury ion transmembrane transporter activity
ETL58_17495	COG1937	Protein conserved in bacteria
ETL58_17500	COG0673	inositol 2-dehydrogenase activity
ETL58_17505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ETL58_17510	COG1289	transmembrane transporter activity
ETL58_17520	COG2076	Multidrug Resistance protein
ETL58_17525	COG1309	transcriptional regulator
ETL58_17530	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_17540	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ETL58_17545	COG0557	exoribonuclease II activity
ETL58_17550	COG1647	Serine aminopeptidase, S33
ETL58_17555	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ETL58_17560	COG0596	Alpha beta hydrolase
ETL58_17565	COG1476	TRANSCRIPTIONal
ETL58_17570	COG1396	sequence-specific DNA binding
ETL58_17575	COG1396	sequence-specific DNA binding
ETL58_17580	COG1733	regulation of RNA biosynthetic process
ETL58_17585	COG0840	transmembrane signaling receptor activity
ETL58_17590	COG1174	glycine betaine transport
ETL58_17595	COG1732	Glycine betaine
ETL58_17600	COG1174	glycine betaine transport
ETL58_17605	COG1125	glycine betaine transport
ETL58_17605	COG0517	IMP dehydrogenase activity
ETL58_17610	COG1510	regulation of RNA biosynthetic process
ETL58_17615	COG1174	glycine betaine transport
ETL58_17620	COG1732	Glycine betaine
ETL58_17625	COG1174	glycine betaine transport
ETL58_17630	COG1125	glycine betaine transport
ETL58_17630	COG0517	IMP dehydrogenase activity
ETL58_17635	COG1510	regulation of RNA biosynthetic process
ETL58_17640	COG2095	MarC family integral membrane protein
ETL58_17650	COG3064	Membrane
ETL58_17655	COG4640	response to antibiotic
ETL58_17660	COG0456	acetyltransferase
ETL58_17665	COG0148	phosphopyruvate hydratase activity
ETL58_17670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ETL58_17675	COG0149	triose-phosphate isomerase activity
ETL58_17680	COG0126	phosphoglycerate kinase activity
ETL58_17685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETL58_17690	COG2390	Transcriptional regulator
ETL58_17695	COG2814	Major facilitator Superfamily
ETL58_17700	COG1609	Transcriptional regulator
ETL58_17705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_17715	COG0583	DNA-binding transcription factor activity
ETL58_17720	COG0697	spore germination
ETL58_17725	COG1113	amino acid transport
ETL58_17730	COG3858	chitin binding
ETL58_17735	COG1556	Lactate utilization protein
ETL58_17740	COG1139	Iron-sulfur cluster binding protein
ETL58_17745	COG0247	lactate metabolic process
ETL58_17750	COG2197	response regulator
ETL58_17755	COG4585	Histidine kinase
ETL58_17760	COG0842	Transport permease protein
ETL58_17765	COG1131	(ABC) transporter
ETL58_17770	COG0596	Alpha beta hydrolase
ETL58_17775	COG2208	phosphoserine phosphatase activity
ETL58_17780	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ETL58_17785	COG1874	Beta-galactosidase
ETL58_17790	COG3833	ABC-type maltose transport systems, permease component
ETL58_17795	COG1175	transmembrane transport
ETL58_17800	COG2182	Extracellular solute-binding protein
ETL58_17805	COG1609	Transcriptional regulator
ETL58_17810	COG2186	Transcriptional regulator
ETL58_17815	COG1620	l-lactate permease
ETL58_17820	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ETL58_17830	COG5039	Polysaccharide pyruvyl transferase
ETL58_17835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETL58_17840	COG0110	maltose O-acetyltransferase activity
ETL58_17845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ETL58_17850	COG2244	polysaccharide biosynthetic process
ETL58_17855	COG1216	Glycosyl transferase, family 2
ETL58_17860	COG5039	Polysaccharide pyruvyl transferase
ETL58_17865	COG1216	Glycosyl transferase, family 2
ETL58_17875	COG0438	transferase activity, transferring glycosyl groups
ETL58_17880	COG1215	transferase activity, transferring glycosyl groups
ETL58_17885	COG0438	transferase activity, transferring glycosyl groups
ETL58_17890	COG1086	Polysaccharide biosynthesis protein
ETL58_17895	COG0489	protein tyrosine kinase activity
ETL58_17900	COG3944	biosynthesis protein
ETL58_17905	COG1396	sequence-specific DNA binding
ETL58_17910	COG2272	Belongs to the type-B carboxylesterase lipase family
ETL58_17920	COG3479	Phenolic acid decarboxylase
ETL58_17930	COG1794	racemase activity, acting on amino acids and derivatives
ETL58_17935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETL58_17940	COG1621	beta-fructofuranosidase activity
ETL58_17945	COG1621	beta-fructofuranosidase activity
ETL58_17950	COG0531	amino acid
ETL58_17955	COG1309	transcriptional regulator
ETL58_17960	COG2076	Multidrug Resistance protein
ETL58_17965	COG2076	Multidrug Resistance protein
ETL58_17975	COG0277	FAD linked oxidase domain protein
ETL58_17980	COG3621	Patatin-like phospholipase
ETL58_17990	COG0740	serine-type endopeptidase activity
ETL58_17995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETL58_18000	COG0366	Alpha amylase catalytic
ETL58_18005	COG1554	hydrolase, family 65, central catalytic
ETL58_18010	COG5521	maltodextrose utilization protein MalA
ETL58_18015	COG3833	ABC-type maltose transport systems, permease component
ETL58_18020	COG1175	transmembrane transport
ETL58_18025	COG2182	Extracellular solute-binding protein
ETL58_18035	COG1609	Transcriptional regulator
ETL58_18040	COG1611	Belongs to the LOG family
ETL58_18045	COG1694	Mazg nucleotide pyrophosphohydrolase
ETL58_18050	COG0659	secondary active sulfate transmembrane transporter activity
ETL58_18055	COG0288	reversible hydration of carbon dioxide
ETL58_18065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETL58_18070	COG0577	efflux transmembrane transporter activity
ETL58_18075	COG1136	(ABC) transporter
ETL58_18080	COG5002	protein histidine kinase activity
ETL58_18085	COG0745	RESPONSE REGULATOR receiver
ETL58_18095	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ETL58_18100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_18105	COG1481	regulation of sporulation
ETL58_18110	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ETL58_18115	COG1660	Displays ATPase and GTPase activities
ETL58_18120	COG1051	belongs to the nudix hydrolase family
ETL58_18125	COG0492	ferredoxin-NADP+ reductase activity
ETL58_18130	COG3883	PFAM NLP P60 protein
ETL58_18130	COG0791	NLP P60 protein
ETL58_18135	COG0457	Tetratricopeptide repeat
ETL58_18140	COG1132	(ABC) transporter
ETL58_18165	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ETL58_18165	COG0140	phosphoribosyl-ATP diphosphatase activity
ETL58_18170	COG0107	imidazoleglycerol-phosphate synthase activity
ETL58_18175	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ETL58_18180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ETL58_18185	COG0131	Imidazoleglycerol-phosphate dehydratase
ETL58_18190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ETL58_18195	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ETL58_18200	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ETL58_18205	COG4990	cell redox homeostasis
ETL58_18210	COG5297	Belongs to the glycosyl hydrolase family 6
ETL58_18215	COG0110	maltose O-acetyltransferase activity
ETL58_18220	COG0546	phosphoglycolate phosphatase activity
ETL58_18225	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ETL58_18230	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ETL58_18235	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ETL58_18240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ETL58_18245	COG0363	glucosamine-6-phosphate deaminase activity
ETL58_18255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ETL58_18260	COG1846	Transcriptional regulator
ETL58_18265	COG2124	cytochrome p450
ETL58_18275	COG1846	Transcriptional regulator
ETL58_18280	COG2814	Major facilitator Superfamily
ETL58_18285	COG1950	PFAM Membrane protein of
ETL58_18290	COG1983	PspC domain protein
ETL58_18295	COG3595	metallopeptidase activity
ETL58_18310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETL58_18315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETL58_18325	COG4897	Protein conserved in bacteria
ETL58_18330	COG0574	Belongs to the PEP-utilizing enzyme family
ETL58_18330	COG3848	Pyruvate phosphate dikinase
ETL58_18335	COG1309	transcriptional regulator
ETL58_18340	COG2814	Major facilitator Superfamily
ETL58_18345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETL58_18355	COG0793	Belongs to the peptidase S41A family
ETL58_18355	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_18360	COG2177	Part of the ABC transporter FtsEX involved in
ETL58_18365	COG2884	Cell division ATP-binding protein ftsE
ETL58_18370	COG2010	Cytochrome c
ETL58_18375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_18385	COG0653	protein targeting
ETL58_18390	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ETL58_18405	COG1516	flagellar protein fliS
ETL58_18410	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ETL58_18415	COG1334	flagellar protein FlaG
ETL58_18420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETL58_18425	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETL58_18430	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ETL58_18440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETL58_18445	COG4786	Flagellar basal body rod
ETL58_18445	COG1256	bacterial-type flagellum assembly
ETL58_18450	COG3418	PFAM FlgN family protein
ETL58_18455	COG2747	anti-sigma28 factor FlgM
ETL58_18465	COG1040	competence protein
ETL58_18475	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ETL58_18480	COG1307	EDD domain protein, DegV family
ETL58_18485	COG2197	response regulator
ETL58_18490	COG4585	Histidine kinase
ETL58_18495	COG1739	Uncharacterized protein family UPF0029
ETL58_18500	COG1316	TRANSCRIPTIONal
ETL58_18505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETL58_18510	COG0438	transferase activity, transferring glycosyl groups
ETL58_18515	COG1215	transferase activity, transferring glycosyl groups
ETL58_18520	COG3206	protein involved in exopolysaccharide biosynthesis
ETL58_18525	COG3307	-O-antigen
ETL58_18530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETL58_18535	COG0438	transferase activity, transferring glycosyl groups
ETL58_18535	COG0297	glycogen (starch) synthase activity
ETL58_18540	COG2244	polysaccharide biosynthetic process
ETL58_18555	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_18555	COG2247	cell wall binding repeat
ETL58_18560	COG2385	sporulation resulting in formation of a cellular spore
ETL58_18560	COG2247	cell wall binding repeat
ETL58_18570	COG1316	TRANSCRIPTIONal
ETL58_18575	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ETL58_18595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETL58_18600	COG1134	teichoic acid transport
ETL58_18605	COG1682	transport, permease protein
ETL58_18625	COG0463	Glycosyl transferase, family 2
ETL58_18670	COG4193	domain, Protein
ETL58_18675	COG1482	cell wall glycoprotein biosynthetic process
ETL58_18680	COG0697	spore germination
ETL58_18685	COG0814	amino acid
ETL58_18695	COG2814	Major facilitator Superfamily
ETL58_18700	COG1316	TRANSCRIPTIONal
ETL58_18705	COG0561	phosphatase activity
ETL58_18710	COG0791	NLP P60 protein
ETL58_18720	COG2843	Capsule synthesis protein
ETL58_18730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ETL58_18740	COG1609	Transcriptional regulator
ETL58_18745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETL58_18750	COG1869	D-ribose catabolic process
ETL58_18755	COG1129	ABC transporter
ETL58_18760	COG1172	Belongs to the binding-protein-dependent transport system permease family
ETL58_18765	COG1879	ABC-type sugar transport system periplasmic component
ETL58_18770	COG3103	Sh3 type 3 domain protein
ETL58_18780	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETL58_18785	COG3527	Alpha-acetolactate decarboxylase
ETL58_18790	COG0028	Belongs to the TPP enzyme family
ETL58_18795	COG0583	DNA-binding transcription factor activity
ETL58_18800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ETL58_18815	COG5337	Spore coat protein CotH
ETL58_18825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETL58_18835	COG0405	Gamma-glutamyltransferase
ETL58_18840	COG1522	sequence-specific DNA binding
ETL58_18845	COG2059	Chromate
ETL58_18850	COG2059	Chromate
ETL58_18860	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETL58_18865	COG0583	DNA-binding transcription factor activity
ETL58_18880	COG5444	nuclease activity
ETL58_18900	COG3878	Protein conserved in bacteria
ETL58_18905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETL58_18910	COG4464	protein tyrosine phosphatase activity
ETL58_18915	COG0489	protein tyrosine kinase activity
ETL58_18920	COG3944	biosynthesis protein
ETL58_18930	COG4715	Zinc finger, swim domain protein
ETL58_18935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETL58_18945	COG0561	phosphatase activity
ETL58_18950	COG1349	DNA-binding transcription factor activity
ETL58_18955	COG0629	single-stranded DNA binding
ETL58_18970	COG3764	Sortase (surface protein transpeptidase)
ETL58_18975	COG0745	RESPONSE REGULATOR receiver
ETL58_18975	COG2972	Histidine kinase
ETL58_18980	COG1970	mechanosensitive ion channel activity
ETL58_18985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETL58_18990	COG0457	Tetratricopeptide repeat
ETL58_18995	COG4786	Flagellar basal body rod
ETL58_19000	COG4786	Flagellar basal body rod
ETL58_19005	COG1077	Cell shape determining protein MreB Mrl
ETL58_19010	COG1609	Transcriptional regulator
ETL58_19020	COG1846	Transcriptional regulator
ETL58_19025	COG2814	Major facilitator Superfamily
ETL58_19030	COG3420	alginic acid biosynthetic process
ETL58_19035	COG1953	Uracil, thiamine, allantoin
ETL58_19040	COG0477	Major facilitator Superfamily
ETL58_19045	COG1335	isochorismatase
ETL58_19055	COG0004	ammonium transporteR
ETL58_19060	COG0347	Belongs to the P(II) protein family
ETL58_19065	COG0671	phosphoesterase, PA-phosphatase related
ETL58_19075	COG0739	heme binding
ETL58_19080	COG1247	-acetyltransferase
ETL58_19100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETL58_19105	COG0789	Transcriptional regulator
ETL58_19115	COG2910	NAD(P)H-binding
ETL58_19120	COG1959	2 iron, 2 sulfur cluster binding
ETL58_19125	COG0804	urea catabolic process
ETL58_19130	COG0832	Belongs to the urease beta subunit family
ETL58_19135	COG0831	urea catabolic process
ETL58_19150	COG3237	CsbD-like
ETL58_19155	COG1994	Peptidase M50
ETL58_19160	COG0457	Tetratricopeptide repeat
ETL58_19165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ETL58_19170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ETL58_19180	COG2304	oxidoreductase activity
ETL58_19190	COG2304	oxidoreductase activity
ETL58_19195	COG2385	sporulation resulting in formation of a cellular spore
ETL58_19200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ETL58_19210	COG4836	Membrane
ETL58_19220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ETL58_19225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ETL58_19230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ETL58_19235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ETL58_19240	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETL58_19245	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ETL58_19250	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETL58_19255	COG0356	it plays a direct role in the translocation of protons across the membrane
ETL58_19265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ETL58_19270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ETL58_19275	COG4475	Protein of unknown function (DUF436)
ETL58_19280	COG0698	ribose 5-phosphate isomerase
ETL58_19285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETL58_19290	COG1971	Probably functions as a manganese efflux pump
ETL58_19295	COG0009	L-threonylcarbamoyladenylate synthase
ETL58_19300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ETL58_19320	COG2890	protein-(glutamine-N5) methyltransferase activity
ETL58_19325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETL58_19330	COG0346	lactoylglutathione lyase activity
ETL58_19335	COG0789	Transcriptional regulator
ETL58_19340	COG0679	Auxin Efflux Carrier
ETL58_19345	COG0281	malic enzyme
ETL58_19350	COG1435	thymidine kinase activity
ETL58_19355	COG0254	rRNA binding
ETL58_19360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETL58_19370	COG1494	fructose-1,6-bisphosphatase
ETL58_19375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ETL58_19380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ETL58_19385	COG0191	fructose-bisphosphate aldolase activity
ETL58_19390	COG2204	response regulator
ETL58_19395	COG4821	SIS domain
ETL58_19400	COG0504	CTP synthase activity
ETL58_19405	COG3343	RNA polymerase activity
ETL58_19410	COG1960	acyl-CoA dehydrogenase activity
ETL58_19415	COG2181	nitrate reductase activity
ETL58_19415	COG0247	lactate metabolic process
ETL58_19420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETL58_19425	COG4294	response to UV
ETL58_19435	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETL58_19440	COG1132	(ABC) transporter
ETL58_19445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETL58_19455	COG2181	nitrate reductase activity
ETL58_19460	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ETL58_19465	COG1140	nitrate reductase beta subunit
ETL58_19470	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ETL58_19475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETL58_19485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETL58_19490	COG2223	nitrite transmembrane transporter activity
ETL58_19495	COG0018	arginyl-trna synthetase
ETL58_19500	COG4506	Protein conserved in bacteria
ETL58_19515	COG0535	radical SAM domain protein
ETL58_19525	COG1131	(ABC) transporter
ETL58_19530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETL58_19535	COG0612	Peptidase, M16
ETL58_19540	COG0612	Peptidase, M16
ETL58_19550	COG3391	amine dehydrogenase activity
ETL58_19555	COG3391	amine dehydrogenase activity
ETL58_19565	COG0457	Tetratricopeptide repeat
ETL58_19595	COG1131	(ABC) transporter
ETL58_19605	COG0010	Belongs to the arginase family
ETL58_19610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETL58_19615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETL58_19630	COG1994	Peptidase M50
ETL58_19635	COG1942	4-Oxalocrotonate Tautomerase
ETL58_19640	COG1846	Transcriptional regulator
ETL58_19645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETL58_19655	COG0477	Major facilitator Superfamily
ETL58_19660	COG1959	2 iron, 2 sulfur cluster binding
ETL58_19665	COG3465	dGTPase activity
ETL58_19670	COG1078	dGTPase activity
ETL58_19675	COG4844	belongs to the
ETL58_19685	COG0697	spore germination
ETL58_19690	COG0095	Lipoate-protein ligase
ETL58_19695	COG0583	DNA-binding transcription factor activity
ETL58_19700	COG0280	phosphate acetyltransferase
ETL58_19710	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_19715	COG0436	Aminotransferase
ETL58_19720	COG2814	Major facilitator Superfamily
ETL58_19725	COG0151	Belongs to the GarS family
ETL58_19730	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_19735	COG1917	Cupin 2, conserved barrel domain protein
ETL58_19740	COG0077	Prephenate dehydratase
ETL58_19745	COG2814	Major facilitator Superfamily
ETL58_19750	COG0833	amino acid
ETL58_19755	COG4187	Peptidase family M20/M25/M40
ETL58_19760	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_19765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETL58_19775	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ETL58_19780	COG1091	dTDP-4-dehydrorhamnose reductase activity
ETL58_19785	COG1088	dTDP-glucose 4,6-dehydratase activity
ETL58_19790	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ETL58_19795	COG3980	spore coat polysaccharide biosynthesis protein
ETL58_19800	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
ETL58_19805	COG2089	acid synthase
ETL58_19810	COG0456	acetyltransferase
ETL58_19815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETL58_19820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETL58_19825	COG0463	Glycosyl transferase, family 2
ETL58_19840	COG2363	Small membrane protein
ETL58_19845	COG2233	PERMEase
ETL58_19855	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_19860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ETL58_19865	COG1216	Glycosyl transferase, family 2
ETL58_19880	COG1695	Transcriptional regulator
ETL58_19885	COG0351	phosphomethylpyrimidine kinase
ETL58_19895	COG1621	beta-fructofuranosidase activity
ETL58_19900	COG1263	PTS System
ETL58_19900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_19905	COG2116	formate transmembrane transporter activity
ETL58_19910	COG3711	transcriptional antiterminator
ETL58_19920	COG1404	Belongs to the peptidase S8 family
ETL58_19925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_19930	COG0778	Nitroreductase
ETL58_19935	COG0772	Belongs to the SEDS family
ETL58_19945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ETL58_19950	COG1845	cytochrome c oxidase, subunit III
ETL58_19955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETL58_19960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETL58_19965	COG2261	transglycosylase associated protein
ETL58_19970	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ETL58_19975	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ETL58_19980	COG2246	polysaccharide biosynthetic process
ETL58_19985	COG1309	transcriptional regulator
ETL58_19995	COG3162	membrane
ETL58_20000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETL58_20005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ETL58_20010	COG2837	iron assimilation
ETL58_20015	COG2822	iron ion transport
ETL58_20020	COG0672	)-iron permease
ETL58_20025	COG0352	thiamine-phosphate diphosphorylase activity
ETL58_20030	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ETL58_20035	COG0583	DNA-binding transcription factor activity
ETL58_20040	COG1380	Effector of murein hydrolase LrgA
ETL58_20045	COG1346	cytolysis
ETL58_20050	COG2814	Major facilitator Superfamily
ETL58_20055	COG4895	conserved protein (DUF2196)
ETL58_20060	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETL58_20065	COG0346	lactoylglutathione lyase activity
ETL58_20070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETL58_20075	COG1404	Belongs to the peptidase S8 family
ETL58_20080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_20080	COG1263	PTS System
ETL58_20085	COG3711	transcriptional antiterminator
ETL58_20090	COG1442	glycosyl transferase family 8
ETL58_20095	COG5522	Integral membrane protein (intg_mem_TP0381)
ETL58_20100	COG1846	Transcriptional regulator
ETL58_20105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETL58_20110	COG2234	aminopeptidase activity
ETL58_20125	COG2814	Major facilitator Superfamily
ETL58_20130	COG2357	RelA SpoT domain protein
ETL58_20135	COG1575	Belongs to the MenA family. Type 1 subfamily
ETL58_20155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_20160	COG1696	Membrane protein involved in D-alanine export
ETL58_20165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_20170	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ETL58_20175	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ETL58_20180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETL58_20185	COG1486	melibiose metabolic process
ETL58_20190	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETL58_20195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETL58_20200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETL58_20205	COG3711	transcriptional antiterminator
ETL58_20205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_20215	COG2094	Belongs to the DNA glycosylase MPG family
ETL58_20220	COG0753	catalase activity
ETL58_20225	COG2814	Major facilitator Superfamily
ETL58_20230	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETL58_20235	COG1131	(ABC) transporter
ETL58_20255	COG1595	DNA-templated transcription, initiation
ETL58_20260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ETL58_20265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ETL58_20270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ETL58_20275	COG4988	ABC transporter
ETL58_20280	COG1294	oxidase, subunit
ETL58_20285	COG1271	oxidase subunit
ETL58_20290	COG3493	citrate carrier protein
ETL58_20295	COG0501	Belongs to the peptidase M48B family
ETL58_20305	COG0726	polysaccharide deacetylase
ETL58_20310	COG3842	ATPase activity
ETL58_20315	COG2508	Transcriptional regulator
ETL58_20320	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_20325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_20335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETL58_20340	COG1881	PFAM PEBP family protein
ETL58_20345	COG0583	DNA-binding transcription factor activity
ETL58_20355	COG4585	Histidine kinase
ETL58_20360	COG2197	response regulator
ETL58_20365	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETL58_20375	COG4894	glucomannan catabolic process
ETL58_20380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETL58_20385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETL58_20390	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_20395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ETL58_20400	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETL58_20405	COG2610	gluconate transmembrane transporter activity
ETL58_20410	COG0500	methyltransferase
ETL58_20415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETL58_20430	COG0693	protein deglycase activity
ETL58_20430	COG0753	catalase activity
ETL58_20435	COG2851	Citrate transporter
ETL58_20440	COG2273	Hydrolase Family 16
ETL58_20445	COG3711	transcriptional antiterminator
ETL58_20455	COG2270	Major facilitator Superfamily
ETL58_20460	COG0513	Belongs to the DEAD box helicase family
ETL58_20465	COG2755	lipolytic protein G-D-S-L family
ETL58_20465	COG3401	FG-GAP repeat protein
ETL58_20515	COG3209	COG3209 Rhs family protein
ETL58_20520	COG0697	spore germination
ETL58_20530	COG0789	Transcriptional regulator
ETL58_20550	COG0589	response to stress
ETL58_20555	COG2723	6-phospho-beta-galactosidase activity
ETL58_20560	COG2190	(PTS) system
ETL58_20560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_20560	COG1263	PTS System
ETL58_20585	COG5444	nuclease activity
ETL58_20605	COG0494	nUDIX hydrolase
ETL58_20610	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ETL58_20615	COG3507	Belongs to the glycosyl hydrolase 43 family
ETL58_20625	COG2986	histidine ammonia-lyase
ETL58_20630	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ETL58_20635	COG1228	amidohydrolase
ETL58_20640	COG0010	Belongs to the arginase family
ETL58_20645	COG0833	amino acid
ETL58_20650	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ETL58_20655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETL58_20660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ETL58_20665	COG2390	Transcriptional regulator
ETL58_20675	COG3192	ethanolamine utilization protein
ETL58_20680	COG2079	MmgE PrpD family protein
ETL58_20690	COG1126	abc transporter atp-binding protein
ETL58_20695	COG0765	amino acid transport
ETL58_20700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_20720	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ETL58_20725	COG0561	phosphatase activity
ETL58_20755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_20760	COG5294	Protein conserved in bacteria
ETL58_20765	COG0577	efflux transmembrane transporter activity
ETL58_20770	COG1136	(ABC) transporter
ETL58_20775	COG2205	protein histidine kinase activity
ETL58_20780	COG0745	RESPONSE REGULATOR receiver
ETL58_20785	COG0191	fructose-bisphosphate aldolase activity
ETL58_20790	COG1082	Xylose isomerase domain protein TIM barrel
ETL58_20795	COG1082	Xylose isomerase domain protein TIM barrel
ETL58_20800	COG0673	inositol 2-dehydrogenase activity
ETL58_20805	COG2814	Major facilitator Superfamily
ETL58_20810	COG1082	Xylose isomerase domain protein TIM barrel
ETL58_20815	COG3962	Belongs to the TPP enzyme family
ETL58_20820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETL58_20830	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_20835	COG1349	DNA-binding transcription factor activity
ETL58_20840	COG0667	Aldo Keto reductase
ETL58_20855	COG2814	Major facilitator Superfamily
ETL58_20860	COG0326	Molecular chaperone. Has ATPase activity
ETL58_20870	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_20875	COG1309	transcriptional regulator
ETL58_20880	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_20885	COG0456	acetyltransferase
ETL58_20890	COG2850	peptidyl-arginine hydroxylation
ETL58_20895	COG2226	methyltransferase
ETL58_20910	COG0367	asparagine synthase
ETL58_20915	COG2814	Major facilitator Superfamily
ETL58_20920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETL58_20930	COG1714	RDD family
ETL58_20935	COG2311	Membrane
ETL58_20940	COG1917	Cupin 2, conserved barrel domain protein
ETL58_20945	COG1309	transcriptional regulator
ETL58_20950	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_20955	COG1846	Transcriptional regulator
ETL58_20960	COG1380	Effector of murein hydrolase LrgA
ETL58_20965	COG1346	cytolysis
ETL58_20970	COG5039	Polysaccharide pyruvyl transferase
ETL58_20975	COG1929	Belongs to the glycerate kinase type-1 family
ETL58_20980	COG1802	Transcriptional regulator
ETL58_20985	COG1070	Carbohydrate kinase
ETL58_20990	COG2610	gluconate transmembrane transporter activity
ETL58_20995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETL58_21000	COG0450	alkyl hydroperoxide reductase
ETL58_21005	COG3634	alkyl hydroperoxide reductase activity
ETL58_21015	COG2723	6-phospho-beta-galactosidase activity
ETL58_21030	COG2188	Transcriptional regulator
ETL58_21040	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ETL58_21075	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ETL58_21090	COG1063	alcohol dehydrogenase
ETL58_21110	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ETL58_21115	COG0456	acetyltransferase
ETL58_21120	COG0457	Tetratricopeptide repeat
ETL58_21130	COG0010	Belongs to the arginase family
ETL58_21135	COG0833	amino acid
ETL58_21140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETL58_21145	COG3829	transcription factor binding
ETL58_21150	COG5002	protein histidine kinase activity
ETL58_21175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETL58_21180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETL58_21185	COG4853	Protein conserved in bacteria
ETL58_21190	COG4863	YycH protein
ETL58_21195	COG5002	protein histidine kinase activity
ETL58_21200	COG0745	RESPONSE REGULATOR receiver
ETL58_21230	COG0346	lactoylglutathione lyase activity
ETL58_21235	COG0305	Participates in initiation and elongation during chromosome replication
ETL58_21250	COG3093	addiction module antidote protein HigA
ETL58_21255	COG2807	transmembrane transport
ETL58_21260	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETL58_21265	COG0359	binds to the 23S rRNA
ETL58_21270	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ETL58_21275	COG4241	membrane
ETL58_21285	COG5577	PFAM Coat F domain
ETL58_21290	COG1733	regulation of RNA biosynthetic process
ETL58_21295	COG1227	inorganic diphosphatase activity
ETL58_21305	COG2271	Major facilitator Superfamily
ETL58_21310	COG0789	Transcriptional regulator
ETL58_21310	COG4978	Transcriptional regulator
ETL58_21320	COG4319	ketosteroid isomerase
ETL58_21325	COG1357	PFAM Pentapeptide repeats (8 copies)
ETL58_21330	COG2814	Major facilitator Superfamily
ETL58_21335	COG0583	DNA-binding transcription factor activity
ETL58_21340	COG2153	protein acetylation
ETL58_21355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_21360	COG1846	Transcriptional regulator
ETL58_21365	COG2153	protein acetylation
ETL58_21370	COG2364	Membrane
ETL58_21375	COG0456	acetyltransferase
ETL58_21380	COG2315	Protein conserved in bacteria
ETL58_21385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETL58_21395	COG2814	Major facilitator Superfamily
ETL58_21405	COG1331	Highly conserved protein containing a thioredoxin domain
ETL58_21410	COG1266	CAAX protease self-immunity
ETL58_21415	COG0477	Major facilitator Superfamily
ETL58_21415	COG2814	Major facilitator Superfamily
ETL58_21420	COG0110	maltose O-acetyltransferase activity
ETL58_21425	COG0346	lactoylglutathione lyase activity
ETL58_21430	COG1609	Transcriptional regulator
ETL58_21435	COG0708	Exodeoxyribonuclease III
ETL58_21440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ETL58_21445	COG0629	single-stranded DNA binding
ETL58_21450	COG0360	Binds together with S18 to 16S ribosomal RNA
ETL58_21455	COG0012	GTP binding
ETL58_21460	COG0243	molybdopterin cofactor binding
ETL58_21465	COG4481	Protein conserved in bacteria
ETL58_21470	COG3949	Membrane
ETL58_21480	COG1475	DNA binding
ETL58_21485	COG1192	Involved in chromosome partitioning
ETL58_21495	COG1475	DNA binding
ETL58_21500	COG0357	Ribosomal RNA small subunit methyltransferase G
ETL58_21505	COG0445	tRNA wobble uridine modification
ETL58_21510	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETL58_21515	COG1847	R3H domain protein
ETL58_21520	COG0706	membrane insertase activity
ETL58_21525	COG0594	ribonuclease P activity
ETL58_21530	COG0230	Belongs to the bacterial ribosomal protein bL34 family