locus-tag	class	description
ES967_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ES967_00010	COG0592	DNA-directed DNA polymerase activity
ES967_00015	COG2501	S4 domain
ES967_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ES967_00030	COG0187	DNA topoisomerase II activity
ES967_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ES967_00070	COG0516	GMP reductase activity
ES967_00070	COG0517	IMP dehydrogenase activity
ES967_00075	COG1686	Belongs to the peptidase S11 family
ES967_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ES967_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ES967_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ES967_00100	COG1428	Deoxynucleoside kinase
ES967_00105	COG1428	Deoxynucleoside kinase
ES967_00110	COG1388	LysM domain
ES967_00110	COG3858	chitin binding
ES967_00115	COG1335	isochorismatase
ES967_00120	COG0590	tRNA wobble adenosine to inosine editing
ES967_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ES967_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ES967_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ES967_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
ES967_00190	COG3853	Toxic anion resistance protein (TelA)
ES967_00195	COG1982	Orn Lys Arg decarboxylase major
ES967_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ES967_00205	COG3870	Protein conserved in bacteria
ES967_00210	COG1728	Protein conserved in bacteria
ES967_00215	COG0470	DNA polymerase III
ES967_00220	COG1774	PSP1 C-terminal conserved region
ES967_00225	COG4467	Involved in initiation control of chromosome replication
ES967_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ES967_00235	COG2827	Endonuclease containing a URI domain
ES967_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ES967_00245	COG2002	toxin-antitoxin pair type II binding
ES967_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ES967_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ES967_00255	COG0084	hydrolase, TatD family'
ES967_00260	COG3583	domain protein
ES967_00260	COG3584	3D domain protein
ES967_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ES967_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ES967_00280	COG4466	Protein conserved in bacteria
ES967_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ES967_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ES967_00300	COG0251	oxidation-reduction process
ES967_00305	COG2088	sporulation resulting in formation of a cellular spore
ES967_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ES967_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ES967_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ES967_00325	COG0193	aminoacyl-tRNA hydrolase activity
ES967_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ES967_00340	COG2002	toxin-antitoxin pair type II binding
ES967_00345	COG2244	polysaccharide biosynthetic process
ES967_00350	COG3956	TIGRFAM MazG family protein
ES967_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ES967_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ES967_00375	COG1098	S1 RNA binding domain
ES967_00390	COG2208	phosphoserine phosphatase activity
ES967_00395	COG2304	oxidoreductase activity
ES967_00400	COG0515	serine threonine protein kinase
ES967_00405	COG0037	tRNA processing
ES967_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ES967_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ES967_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ES967_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ES967_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ES967_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ES967_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
ES967_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ES967_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ES967_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ES967_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ES967_00470	COG1396	sequence-specific DNA binding
ES967_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ES967_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ES967_00560	COG4463	regulation of RNA biosynthetic process
ES967_00565	COG3880	PFAM UvrB UvrC protein
ES967_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ES967_00575	COG0542	response to heat
ES967_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ES967_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ES967_00590	COG4956	integral membrane protein (PIN domain superfamily)
ES967_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ES967_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ES967_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ES967_00615	COG1045	serine acetyltransferase
ES967_00620	COG0215	cysteine-tRNA ligase activity
ES967_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ES967_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ES967_00635	COG3688	RNA-binding protein containing a PIN domain
ES967_00640	COG1595	DNA-templated transcription, initiation
ES967_00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ES967_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ES967_00655	COG0250	Participates in transcription elongation, termination and antitermination
ES967_00660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ES967_00665	COG0081	regulation of translation
ES967_00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ES967_00675	COG0222	ribosome binding
ES967_00680	COG2813	Specifically methylates the guanine in position
ES967_00685	COG0085	RNA polymerase activity
ES967_00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ES967_00695	COG1358	cellular component organization or biogenesis
ES967_00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ES967_00705	COG0049	tRNA binding
ES967_00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ES967_00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ES967_00720	COG0596	Alpha beta hydrolase
ES967_00725	COG0051	transcription antitermination factor activity, RNA binding
ES967_00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ES967_00735	COG0088	Forms part of the polypeptide exit tunnel
ES967_00740	COG0089	rRNA binding
ES967_00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ES967_00750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ES967_00755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ES967_00760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ES967_00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ES967_00770	COG0255	Belongs to the universal ribosomal protein uL29 family
ES967_00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ES967_00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ES967_00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ES967_00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ES967_00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ES967_00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ES967_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ES967_00820	COG1841	ribosomal large subunit assembly
ES967_00825	COG0200	Binds to the 23S rRNA
ES967_00830	COG0201	protein transport
ES967_00835	COG0563	adenylate kinase activity
ES967_00840	COG0024	Methionine aminopeptidase
ES967_00845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
ES967_00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ES967_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ES967_00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ES967_00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ES967_00870	COG0202	RNA polymerase activity
ES967_00875	COG0203	ribosomal protein L17
ES967_00880	COG1122	ATPase activity
ES967_00885	COG1122	ATPase activity
ES967_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ES967_00895	COG0101	tRNA pseudouridine synthase activity
ES967_00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ES967_00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ES967_00910	COG2226	methyltransferase
ES967_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
ES967_00925	COG0489	protein tyrosine kinase activity
ES967_00935	COG2194	sulfuric ester hydrolase activity
ES967_00940	COG0726	polysaccharide deacetylase
ES967_00980	COG0659	secondary active sulfate transmembrane transporter activity
ES967_00985	COG0385	Bile acid
ES967_00990	COG2819	hydrolase of the alpha beta superfamily
ES967_00995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES967_01000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES967_01005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ES967_01010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ES967_01010	COG2207	Transcriptional regulator
ES967_01015	COG3876	Protein conserved in bacteria
ES967_01020	COG1472	Belongs to the glycosyl hydrolase 3 family
ES967_01025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ES967_01030	COG1263	PTS System
ES967_01030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_01035	COG1737	Transcriptional regulator
ES967_01040	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ES967_01045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES967_01050	COG1683	Conserved Protein
ES967_01080	COG1595	DNA-templated transcription, initiation
ES967_01085	COG5662	AntiSigma factor
ES967_01090	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ES967_01095	COG4856	YbbR-like protein
ES967_01100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ES967_01105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ES967_01115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ES967_01120	COG2169	Transcriptional regulator
ES967_01125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ES967_01130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ES967_01135	COG3002	Belongs to the UPF0753 family
ES967_01140	COG0288	reversible hydration of carbon dioxide
ES967_01150	COG5609	conserved protein (DUF2294)
ES967_01155	COG0640	Transcriptional regulator
ES967_01160	COG2814	Major facilitator Superfamily
ES967_01175	COG0535	radical SAM domain protein
ES967_01180	COG1266	CAAX protease self-immunity
ES967_01185	COG1131	(ABC) transporter
ES967_01195	COG1413	lyase activity
ES967_01200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES967_01205	COG0596	Alpha beta hydrolase
ES967_01210	COG0745	RESPONSE REGULATOR receiver
ES967_01215	COG0642	Histidine kinase
ES967_01225	COG0515	serine threonine protein kinase
ES967_01240	COG1113	amino acid transport
ES967_01255	COG2602	Beta-lactamase
ES967_01260	COG2124	cytochrome p450
ES967_01270	COG0531	amino acid
ES967_01275	COG0584	glycerophosphoryl diester phosphodiesterase
ES967_01280	COG2271	Major facilitator Superfamily
ES967_01295	COG1846	Transcriptional regulator
ES967_01295	COG0456	acetyltransferase
ES967_01300	COG2271	Major facilitator Superfamily
ES967_01315	COG3409	Peptidoglycan-binding domain 1 protein
ES967_01320	COG0697	spore germination
ES967_01325	COG1917	Cupin 2, conserved barrel domain protein
ES967_01325	COG2207	Transcriptional regulator
ES967_01330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ES967_01335	COG3591	Belongs to the peptidase S1B family
ES967_01345	COG0596	Alpha beta hydrolase
ES967_01350	COG1183	phosphatidylcholine synthase activity
ES967_01355	COG0586	Pfam SNARE associated Golgi protein
ES967_01360	COG0688	phosphatidylethanolamine metabolic process
ES967_01370	COG2312	Erythromycin esterase
ES967_01375	COG2207	Transcriptional regulator
ES967_01385	COG1301	dicarboxylic acid transport
ES967_01390	COG1263	PTS System
ES967_01390	COG2190	(PTS) system
ES967_01390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_01395	COG0363	glucosamine-6-phosphate deaminase activity
ES967_01410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ES967_01415	COG0833	amino acid
ES967_01420	COG2040	homocysteine
ES967_01430	COG1115	amino acid carrier protein
ES967_01435	COG2066	Belongs to the glutaminase family
ES967_01440	COG4191	Histidine kinase
ES967_01445	COG0784	Response regulator, receiver
ES967_01455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ES967_01460	COG1012	belongs to the aldehyde dehydrogenase family
ES967_01465	COG2271	Major facilitator Superfamily
ES967_01470	COG4948	Mandelate Racemase Muconate Lactonizing
ES967_01475	COG2186	Transcriptional regulator
ES967_01480	COG2721	sulfolactate sulfo-lyase activity
ES967_01485	COG3173	Aminoglycoside phosphotransferase
ES967_01495	COG0697	spore germination
ES967_01500	COG0745	RESPONSE REGULATOR receiver
ES967_01505	COG2205	protein histidine kinase activity
ES967_01510	COG1131	(ABC) transporter
ES967_01530	COG3773	Cell wall hydrolase
ES967_01535	COG2304	oxidoreductase activity
ES967_01545	COG3540	Alkaline phosphatase
ES967_01550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ES967_01555	COG0805	protein transport
ES967_01560	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ES967_01565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ES967_01570	COG0477	Major facilitator Superfamily
ES967_01575	COG1309	transcriptional regulator
ES967_01580	COG0252	asparaginase activity
ES967_01585	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ES967_01590	COG1714	RDD family
ES967_01595	COG1405	negative regulation of cell septum assembly
ES967_01595	COG3012	SEC-C Motif Domain Protein
ES967_01600	COG3290	protein histidine kinase activity
ES967_01605	COG3279	Response regulator of the LytR AlgR family
ES967_01610	COG4555	ABC transporter
ES967_01615	COG1668	transmembrane transport
ES967_01635	COG1595	DNA-templated transcription, initiation
ES967_01640	COG1595	DNA-templated transcription, initiation
ES967_01645	COG1876	peptidase activity
ES967_01650	COG0457	Tetratricopeptide repeat
ES967_01655	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_01660	COG0366	Alpha amylase catalytic
ES967_01665	COG0803	Belongs to the bacterial solute-binding protein 9 family
ES967_01670	COG1121	(ABC) transporter
ES967_01675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ES967_01680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ES967_01685	COG2310	stress, protein
ES967_01690	COG2310	stress, protein
ES967_01695	COG2310	stress, protein
ES967_01700	COG0861	Integral membrane protein TerC family
ES967_01710	COG3853	Toxic anion resistance protein (TelA)
ES967_01715	COG0477	Major facilitator Superfamily
ES967_01725	COG2814	Major facilitator Superfamily
ES967_01730	COG0640	Transcriptional regulator
ES967_01735	COG4175	Glycine betaine
ES967_01735	COG0517	IMP dehydrogenase activity
ES967_01740	COG4176	ABC-type proline glycine betaine transport system permease component
ES967_01745	COG2113	Glycine betaine
ES967_01750	COG1473	amidohydrolase
ES967_01755	COG1288	antiporter activity
ES967_01765	COG0366	Alpha amylase catalytic
ES967_01770	COG0039	L-malate dehydrogenase activity
ES967_01775	COG1620	l-lactate permease
ES967_01780	COG2814	Major facilitator Superfamily
ES967_01785	COG1846	Transcriptional regulator
ES967_01790	COG1280	lysine exporter protein (LysE YggA)
ES967_01795	COG3403	YqcI/YcgG family
ES967_01800	COG1113	amino acid transport
ES967_01805	COG3665	Urea carboxylase-associated protein
ES967_01810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ES967_01815	COG1660	Displays ATPase and GTPase activities
ES967_01820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ES967_01825	COG2226	methyltransferase
ES967_01830	COG0583	DNA-binding transcription factor activity
ES967_01835	COG3458	cephalosporin-C deacetylase activity
ES967_01840	COG3541	Predicted nucleotidyltransferase
ES967_01845	COG0506	proline dehydrogenase activity
ES967_01850	COG1012	belongs to the aldehyde dehydrogenase family
ES967_01855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ES967_01860	COG2508	Transcriptional regulator
ES967_01865	COG3689	TIGRFAM TIGR03943 family protein
ES967_01870	COG0701	Predicted permease
ES967_01875	COG2267	carboxylic ester hydrolase activity
ES967_01880	COG0492	ferredoxin-NADP+ reductase activity
ES967_01885	COG1587	Uroporphyrinogen-III synthase
ES967_01885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ES967_01890	COG2146	nitrite reductase [NAD(P)H] activity
ES967_01895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ES967_01900	COG0243	molybdopterin cofactor binding
ES967_01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ES967_01910	COG2223	nitrite transmembrane transporter activity
ES967_01915	COG1469	GTP cyclohydrolase I activity
ES967_01920	COG1376	ErfK ybiS ycfS ynhG family protein
ES967_01930	COG0523	cobalamin synthesis protein
ES967_01935	COG0765	amino acid transport
ES967_01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES967_01950	COG1714	RDD family
ES967_01960	COG2723	6-phospho-beta-galactosidase activity
ES967_01970	COG3209	COG3209 Rhs family protein
ES967_01975	COG0840	transmembrane signaling receptor activity
ES967_01975	COG3290	protein histidine kinase activity
ES967_01980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ES967_01985	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ES967_01990	COG1733	regulation of RNA biosynthetic process
ES967_01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_02000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_02005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_02010	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ES967_02015	COG2814	Major facilitator Superfamily
ES967_02025	COG0697	spore germination
ES967_02030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ES967_02040	COG2364	Membrane
ES967_02045	COG1126	abc transporter atp-binding protein
ES967_02050	COG0765	amino acid transport
ES967_02055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES967_02060	COG0583	DNA-binding transcription factor activity
ES967_02065	COG0163	prenyltransferase activity
ES967_02070	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ES967_02085	COG0596	Alpha beta hydrolase
ES967_02090	COG3104	oligopeptide transport
ES967_02095	COG5434	Belongs to the glycosyl hydrolase 28 family
ES967_02105	COG0697	spore germination
ES967_02115	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ES967_02120	COG1136	(ABC) transporter
ES967_02125	COG0577	efflux transmembrane transporter activity
ES967_02130	COG0745	RESPONSE REGULATOR receiver
ES967_02135	COG3850	Histidine kinase
ES967_02135	COG5002	protein histidine kinase activity
ES967_02140	COG0457	Tetratricopeptide repeat
ES967_02160	COG0527	aspartate kinase activity
ES967_02165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES967_02170	COG4605	iron ion homeostasis
ES967_02175	COG4604	ABC transporter, ATP-binding protein
ES967_02180	COG4607	ABC-type enterochelin transport system periplasmic component
ES967_02185	COG2814	Major facilitator Superfamily
ES967_02190	COG1309	transcriptional regulator
ES967_02195	COG0778	Nitroreductase
ES967_02200	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ES967_02205	COG0640	Transcriptional regulator
ES967_02210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ES967_02215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ES967_02220	COG1012	belongs to the aldehyde dehydrogenase family
ES967_02225	COG4975	Glucose uptake
ES967_02230	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_02235	COG4549	nuclear export factor GLE1
ES967_02240	COG2372	response to copper ion
ES967_02240	COG1276	copper resistance
ES967_02245	COG1349	DNA-binding transcription factor activity
ES967_02255	COG2213	PTS system mannitol-specific
ES967_02260	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES967_02265	COG0246	Mannitol dehydrogenase
ES967_02270	COG0473	3-isopropylmalate dehydrogenase activity
ES967_02275	COG0681	Belongs to the peptidase S26 family
ES967_02280	COG0412	Dienelactone hydrolase
ES967_02285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ES967_02295	COG0561	phosphatase activity
ES967_02300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ES967_02305	COG1914	H( )-stimulated, divalent metal cation uptake system
ES967_02310	COG4336	lyase activity
ES967_02315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ES967_02320	COG1984	allophanate hydrolase subunit 2
ES967_02325	COG1414	Transcriptional regulator
ES967_02330	COG2755	lipolytic protein G-D-S-L family
ES967_02340	COG2329	Antibiotic biosynthesis monooxygenase
ES967_02345	COG0768	penicillin binding
ES967_02350	COG4989	oxidoreductase activity
ES967_02355	COG3711	transcriptional antiterminator
ES967_02360	COG0318	PFAM AMP-dependent synthetase and ligase
ES967_02365	COG2226	methyltransferase
ES967_02370	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_02375	COG1917	Cupin 2, conserved barrel domain protein
ES967_02380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES967_02385	COG3871	stress protein (general stress protein 26)
ES967_02395	COG2814	Major facilitator Superfamily
ES967_02400	COG1522	sequence-specific DNA binding
ES967_02405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ES967_02405	COG0551	DNA topoisomerase type I activity
ES967_02410	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ES967_02415	COG3706	GGDEF domain
ES967_02420	COG5298	Protein conserved in bacteria
ES967_02425	COG1215	transferase activity, transferring glycosyl groups
ES967_02435	COG0531	amino acid
ES967_02440	COG0494	nUDIX hydrolase
ES967_02445	COG0028	Belongs to the TPP enzyme family
ES967_02460	COG1914	H( )-stimulated, divalent metal cation uptake system
ES967_02465	COG2261	transglycosylase associated protein
ES967_02470	COG4876	unkown
ES967_02475	COG2217	Heavy metal translocating P-type atpase
ES967_02480	COG3729	General stress protein
ES967_02485	COG0662	Cupin 2, conserved barrel domain protein
ES967_02490	COG2329	Antibiotic biosynthesis monooxygenase
ES967_02495	COG3546	catalase activity
ES967_02500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ES967_02505	COG3290	protein histidine kinase activity
ES967_02510	COG4565	transcriptional regulatory protein
ES967_02515	COG1301	dicarboxylic acid transport
ES967_02520	COG0628	permease
ES967_02525	COG1131	(ABC) transporter
ES967_02530	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ES967_02540	COG1960	acyl-CoA dehydrogenase activity
ES967_02555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ES967_02560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES967_02565	COG1181	Belongs to the D-alanine--D-alanine ligase family
ES967_02570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ES967_02580	COG0513	Belongs to the DEAD box helicase family
ES967_02585	COG3402	PFAM membrane-flanked domain
ES967_02590	COG3428	Bacterial PH domain
ES967_02595	COG0705	Rhomboid family
ES967_02600	COG0736	holo-[acyl-carrier-protein] synthase activity
ES967_02605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ES967_02610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ES967_02615	COG0864	Transcriptional regulator
ES967_02620	COG2337	Toxic component of a toxin-antitoxin (TA) module
ES967_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
ES967_02630	COG1366	Belongs to the anti-sigma-factor antagonist family
ES967_02635	COG2172	sigma factor antagonist activity
ES967_02640	COG2208	phosphoserine phosphatase activity
ES967_02645	COG1366	Belongs to the anti-sigma-factor antagonist family
ES967_02650	COG2172	sigma factor antagonist activity
ES967_02655	COG1191	sigma factor activity
ES967_02660	COG2208	phosphoserine phosphatase activity
ES967_02675	COG1673	EVE domain
ES967_02680	COG1846	Transcriptional regulator
ES967_02685	COG2183	response to ionizing radiation
ES967_02695	COG3091	SprT-like family
ES967_02735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES967_02745	COG5444	nuclease activity
ES967_02755	COG1476	TRANSCRIPTIONal
ES967_02780	COG0693	protein deglycase activity
ES967_02785	COG1278	Cold shock
ES967_02790	COG1329	Transcriptional regulator
ES967_02800	COG0697	spore germination
ES967_02805	COG2207	Transcriptional regulator
ES967_02805	COG1917	Cupin 2, conserved barrel domain protein
ES967_02810	COG0697	spore germination
ES967_02815	COG3708	Transcriptional regulator
ES967_02815	COG2207	Transcriptional regulator
ES967_02820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ES967_02825	COG0477	Major facilitator Superfamily
ES967_02835	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ES967_02850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES967_02855	COG1309	transcriptional regulator
ES967_02860	COG0697	spore germination
ES967_02865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ES967_02870	COG2030	dehydratase
ES967_02875	COG3545	Serine hydrolase
ES967_02880	COG1733	regulation of RNA biosynthetic process
ES967_02885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ES967_02890	COG1733	regulation of RNA biosynthetic process
ES967_02895	COG2249	NAD(P)H dehydrogenase (quinone) activity
ES967_02900	COG2814	Major facilitator Superfamily
ES967_02905	COG1309	transcriptional regulator
ES967_02910	COG0640	Transcriptional regulator
ES967_02915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ES967_02925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES967_02930	COG0697	spore germination
ES967_02935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ES967_02940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ES967_02945	COG0640	Transcriptional regulator
ES967_02950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ES967_02965	COG4585	Histidine kinase
ES967_02970	COG2197	response regulator
ES967_02975	COG2409	Drug exporters of the RND superfamily
ES967_02980	COG0596	Alpha beta hydrolase
ES967_02985	COG1811	Na channel or pump
ES967_02990	COG4978	Transcriptional regulator
ES967_02990	COG0789	Transcriptional regulator
ES967_02995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ES967_03000	COG0778	Nitroreductase
ES967_03005	COG0346	lactoylglutathione lyase activity
ES967_03010	COG2259	Doxx family
ES967_03015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES967_03030	COG2323	membrane
ES967_03035	COG2323	membrane
ES967_03040	COG0071	Belongs to the small heat shock protein (HSP20) family
ES967_03055	COG1309	transcriptional regulator
ES967_03065	COG0456	acetyltransferase
ES967_03075	COG1113	amino acid transport
ES967_03080	COG2318	DinB family
ES967_03085	COG1846	Transcriptional regulator
ES967_03090	COG1033	growth of symbiont in host cell
ES967_03090	COG2409	Drug exporters of the RND superfamily
ES967_03095	COG0778	Nitroreductase
ES967_03100	COG1846	Transcriptional regulator
ES967_03105	COG2814	Major facilitator Superfamily
ES967_03110	COG0730	response to heat
ES967_03115	COG1802	Transcriptional regulator
ES967_03120	COG3858	chitin binding
ES967_03120	COG1388	LysM domain
ES967_03125	COG1819	glycosyl
ES967_03135	COG1785	Belongs to the alkaline phosphatase family
ES967_03140	COG5646	InterPro IPR014922
ES967_03150	COG0454	-acetyltransferase
ES967_03155	COG1078	dGTPase activity
ES967_03160	COG1388	LysM domain
ES967_03165	COG2814	Major facilitator Superfamily
ES967_03170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES967_03175	COG1447	Phosphotransferase system cellobiose-specific component IIA
ES967_03180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES967_03185	COG2723	6-phospho-beta-galactosidase activity
ES967_03190	COG2188	Transcriptional regulator
ES967_03195	COG1940	carbohydrate kinase activity
ES967_03200	COG1482	cell wall glycoprotein biosynthetic process
ES967_03205	COG4124	Belongs to the glycosyl hydrolase 26 family
ES967_03250	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ES967_03255	COG0802	atpase or kinase
ES967_03260	COG1214	PFAM Peptidase M22, glycoprotease
ES967_03265	COG0456	acetyltransferase
ES967_03270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ES967_03275	COG0488	(ABC) transporter
ES967_03280	COG0315	cyclic pyranopterin monophosphate synthase activity
ES967_03285	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ES967_03290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ES967_03295	COG0805	protein transport
ES967_03310	COG1266	CAAX protease self-immunity
ES967_03315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ES967_03320	COG0459	protein refolding
ES967_03335	COG3378	Phage plasmid primase P4 family
ES967_03350	COG0270	DNA (cytosine-5-)-methyltransferase activity
ES967_03355	COG0270	DNA (cytosine-5-)-methyltransferase activity
ES967_03375	COG1401	restriction endodeoxyribonuclease activity
ES967_03400	COG1073	alpha beta
ES967_03405	COG0457	Tetratricopeptide repeat
ES967_03410	COG1063	alcohol dehydrogenase
ES967_03415	COG2211	Major facilitator Superfamily
ES967_03420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ES967_03425	COG1842	Phage shock protein A
ES967_03430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ES967_03435	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ES967_03440	COG4260	virion core protein, lumpy skin disease virus
ES967_03450	COG2814	Major facilitator Superfamily
ES967_03455	COG1063	alcohol dehydrogenase
ES967_03460	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ES967_03465	COG0823	Involved in the tonB-independent uptake of proteins
ES967_03480	COG2267	carboxylic ester hydrolase activity
ES967_03490	COG2132	Multicopper oxidase
ES967_03495	COG1113	amino acid transport
ES967_03505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ES967_03510	COG0714	Associated with various cellular activities
ES967_03515	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ES967_03520	COG1305	Transglutaminase-like
ES967_03525	COG0519	Catalyzes the synthesis of GMP from XMP
ES967_03525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ES967_03540	COG2252	PERMEase
ES967_03545	COG3064	Membrane
ES967_03555	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ES967_03565	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ES967_03570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ES967_03575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ES967_03580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ES967_03585	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ES967_03590	COG0047	phosphoribosylformylglycinamidine synthase activity
ES967_03595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ES967_03600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ES967_03605	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ES967_03610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ES967_03615	COG0138	bifunctional purine biosynthesis protein purh
ES967_03620	COG0151	Belongs to the GarS family
ES967_03625	COG1522	sequence-specific DNA binding
ES967_03630	COG0531	amino acid
ES967_03640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ES967_03645	COG1470	cell adhesion involved in biofilm formation
ES967_03650	COG4496	protein, YerC YecD
ES967_03655	COG0069	glutamate synthase activity
ES967_03660	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ES967_03665	COG0210	DNA helicase
ES967_03670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ES967_03675	COG4851	CamS sex pheromone cAM373 precursor
ES967_03680	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ES967_03685	COG1285	pathogenesis
ES967_03690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ES967_03695	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ES967_03700	COG0154	amidase activity
ES967_03705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ES967_03710	COG1309	transcriptional regulator
ES967_03715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ES967_03720	COG1597	lipid kinase activity
ES967_03725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ES967_03730	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ES967_03735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ES967_03740	COG1002	Type II restriction enzyme, methylase subunits
ES967_03745	COG1061	Type III restriction enzyme res subunit
ES967_03750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ES967_03770	COG5444	nuclease activity
ES967_03775	COG3391	amine dehydrogenase activity
ES967_03780	COG0457	Tetratricopeptide repeat
ES967_03790	COG0217	transcriptional regulatory protein
ES967_03800	COG1309	transcriptional regulator
ES967_03805	COG3631	Ketosteroid isomerase-related protein
ES967_03810	COG0702	epimerase
ES967_03825	COG3546	catalase activity
ES967_03830	COG0454	-acetyltransferase
ES967_03840	COG5578	integral membrane protein
ES967_03845	COG2972	Histidine kinase
ES967_03850	COG4753	response regulator
ES967_03850	COG2207	Transcriptional regulator
ES967_03855	COG1653	transport
ES967_03860	COG1175	transmembrane transport
ES967_03865	COG0395	ABC-type sugar transport system, permease component
ES967_03870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ES967_03875	COG2207	Transcriptional regulator
ES967_03880	COG2755	lipolytic protein G-D-S-L family
ES967_03890	COG5578	integral membrane protein
ES967_03895	COG3401	FG-GAP repeat protein
ES967_03900	COG3401	FG-GAP repeat protein
ES967_03905	COG2755	lipolytic protein G-D-S-L family
ES967_03910	COG1874	Beta-galactosidase
ES967_03920	COG1653	transport
ES967_03925	COG4209	transmembrane transport
ES967_03930	COG0395	ABC-type sugar transport system, permease component
ES967_03935	COG1486	melibiose metabolic process
ES967_03940	COG2323	membrane
ES967_03945	COG2329	Antibiotic biosynthesis monooxygenase
ES967_03950	COG0346	lactoylglutathione lyase activity
ES967_03965	COG5583	Uncharacterized small protein (DUF2292)
ES967_03970	COG0670	Belongs to the BI1 family
ES967_03975	COG0697	spore germination
ES967_03980	COG1846	Transcriptional regulator
ES967_03985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ES967_03995	COG2124	cytochrome p450
ES967_03995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ES967_04000	COG1368	sulfuric ester hydrolase activity
ES967_04005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ES967_04010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ES967_04015	COG1442	glycosyl transferase family 8
ES967_04020	COG1216	Glycosyl transferase, family 2
ES967_04025	COG1442	glycosyl transferase family 8
ES967_04030	COG2223	nitrite transmembrane transporter activity
ES967_04035	COG1011	Hydrolase
ES967_04040	COG0531	amino acid
ES967_04045	COG1012	belongs to the aldehyde dehydrogenase family
ES967_04050	COG0840	transmembrane signaling receptor activity
ES967_04055	COG0488	(ABC) transporter
ES967_04065	COG0789	Transcriptional regulator
ES967_04070	COG2814	Major facilitator Superfamily
ES967_04085	COG0488	(ABC) transporter
ES967_04090	COG0513	Belongs to the DEAD box helicase family
ES967_04095	COG0456	acetyltransferase
ES967_04100	COG2130	NADP-dependent
ES967_04110	COG2211	Major facilitator Superfamily
ES967_04115	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ES967_04120	COG1120	ATPase activity
ES967_04125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES967_04130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES967_04135	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ES967_04150	COG3866	Pectate lyase
ES967_04155	COG0471	metal ion transport
ES967_04160	COG3290	protein histidine kinase activity
ES967_04165	COG4565	transcriptional regulatory protein
ES967_04170	COG3181	Tripartite tricarboxylate transporter family receptor
ES967_04175	COG2851	Citrate transporter
ES967_04180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ES967_04185	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ES967_04190	COG1254	Belongs to the acylphosphatase family
ES967_04195	COG2258	MOSC domain
ES967_04215	COG0024	Methionine aminopeptidase
ES967_04220	COG1263	PTS System
ES967_04220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_04225	COG1368	sulfuric ester hydrolase activity
ES967_04240	COG1115	amino acid carrier protein
ES967_04245	COG0531	amino acid
ES967_04260	COG0697	spore germination
ES967_04265	COG1263	PTS System
ES967_04265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_04270	COG0366	Alpha amylase catalytic
ES967_04275	COG2188	Transcriptional regulator
ES967_04280	COG0778	Nitroreductase
ES967_04285	COG0737	Belongs to the 5'-nucleotidase family
ES967_04290	COG0693	protein deglycase activity
ES967_04295	COG2814	Major facilitator Superfamily
ES967_04300	COG4840	Belongs to the UPF0435 family
ES967_04305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ES967_04310	COG4980	gas vesicle protein
ES967_04315	COG1295	ribonuclease BN
ES967_04320	COG0477	Major facilitator Superfamily
ES967_04325	COG0387	Pfam Sodium calcium exchanger
ES967_04335	COG0668	transmembrane transport
ES967_04340	COG0535	radical SAM domain protein
ES967_04350	COG0726	polysaccharide deacetylase
ES967_04355	COG2084	Dehydrogenase
ES967_04360	COG0598	Magnesium transport protein CorA
ES967_04365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ES967_04370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ES967_04380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ES967_04385	COG4637	Psort location Cytoplasmic, score
ES967_04395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ES967_04400	COG0022	dehydrogenase e1 component
ES967_04405	COG0508	dehydrogenase complex catalyzes the overall conversion of
ES967_04410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ES967_04415	COG3284	Transcriptional regulator
ES967_04425	COG1742	UPF0060 membrane protein
ES967_04450	COG4842	Belongs to the WXG100 family
ES967_04455	COG1486	melibiose metabolic process
ES967_04460	COG1737	Transcriptional regulator
ES967_04465	COG1263	PTS System
ES967_04465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_04470	COG1132	(ABC) transporter
ES967_04475	COG1132	(ABC) transporter
ES967_04480	COG2259	Doxx family
ES967_04485	COG2514	catechol 2,3-dioxygenase activity
ES967_04490	COG4977	sequence-specific DNA binding
ES967_04490	COG1917	Cupin 2, conserved barrel domain protein
ES967_04495	COG2814	Major facilitator Superfamily
ES967_04500	COG1082	Xylose isomerase domain protein TIM barrel
ES967_04505	COG0673	inositol 2-dehydrogenase activity
ES967_04510	COG4585	Histidine kinase
ES967_04515	COG2197	response regulator
ES967_04520	COG1131	(ABC) transporter
ES967_04525	COG0842	Transport permease protein
ES967_04525	COG1511	domain protein
ES967_04530	COG0842	Transport permease protein
ES967_04535	COG1695	Transcriptional regulator
ES967_04540	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ES967_04545	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ES967_04550	COG1309	transcriptional regulator
ES967_04555	COG2814	Major facilitator Superfamily
ES967_04560	COG2318	DinB family
ES967_04565	COG2814	Major facilitator Superfamily
ES967_04570	COG1846	Transcriptional regulator
ES967_04575	COG0392	lysyltransferase activity
ES967_04575	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ES967_04580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ES967_04585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES967_04590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES967_04595	COG0384	phenazine biosynthesis protein PhzF
ES967_04600	COG0778	Nitroreductase
ES967_04615	COG1090	epimerase
ES967_04620	COG2137	regulation of response to DNA damage stimulus
ES967_04630	COG2814	Major facilitator Superfamily
ES967_04645	COG3103	Sh3 type 3 domain protein
ES967_04650	COG5658	integral membrane protein
ES967_04655	COG0596	Alpha beta hydrolase
ES967_04660	COG0463	Glycosyl transferase, family 2
ES967_04665	COG4485	Bacterial membrane protein, YfhO
ES967_04670	COG1988	membrane-bound metal-dependent
ES967_04675	COG1194	a g-specific adenine glycosylase
ES967_04685	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_04700	COG3557	Belongs to the UPF0374 family
ES967_04705	COG1132	(ABC) transporter
ES967_04710	COG4129	membrane
ES967_04715	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ES967_04720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ES967_04725	COG0735	belongs to the Fur family
ES967_04835	COG4326	sporulation control protein
ES967_04845	COG5577	PFAM Coat F domain
ES967_04850	COG3340	Belongs to the peptidase S51 family
ES967_04855	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ES967_04860	COG0277	FAD linked oxidase domain protein
ES967_04870	COG0753	catalase activity
ES967_04875	COG1116	anion transmembrane transporter activity
ES967_04880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ES967_04885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ES967_04890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ES967_04900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ES967_04910	COG1476	TRANSCRIPTIONal
ES967_04920	COG3382	B3 4 domain protein
ES967_04925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ES967_04935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ES967_04940	COG0789	Transcriptional regulator
ES967_04945	COG1664	Polymer-forming cytoskeletal
ES967_04950	COG1664	Polymer-forming cytoskeletal
ES967_04955	COG2766	serine protein kinase
ES967_04960	COG2718	Belongs to the UPF0229 family
ES967_04965	COG1846	Transcriptional regulator
ES967_04970	COG1566	PFAM secretion protein HlyD family protein
ES967_04975	COG2814	Major facilitator Superfamily
ES967_04980	COG0655	NAD(P)H dehydrogenase (quinone) activity
ES967_05000	COG1725	Transcriptional regulator
ES967_05005	COG1131	(ABC) transporter
ES967_05010	COG1131	(ABC) transporter
ES967_05015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ES967_05020	COG1278	Cold shock
ES967_05030	COG1464	Belongs to the NlpA lipoprotein family
ES967_05035	COG3706	GGDEF domain
ES967_05040	COG1823	symporter activity
ES967_05060	COG5577	PFAM Coat F domain
ES967_05065	COG4085	toxin activity
ES967_05065	COG1525	nuclease
ES967_05065	COG0737	Belongs to the 5'-nucleotidase family
ES967_05070	COG3764	Sortase (surface protein transpeptidase)
ES967_05075	COG0564	pseudouridine synthase activity
ES967_05085	COG0517	IMP dehydrogenase activity
ES967_05090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ES967_05095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ES967_05095	COG3153	acetyltransferase
ES967_05100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ES967_05105	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ES967_05110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ES967_05115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ES967_05120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ES967_05125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ES967_05130	COG2203	Gaf domain
ES967_05130	COG4585	Histidine kinase
ES967_05135	COG2197	response regulator
ES967_05140	COG0431	NADPH-dependent FMN reductase
ES967_05155	COG0791	NLP P60 protein
ES967_05155	COG1388	LysM domain
ES967_05160	COG1959	2 iron, 2 sulfur cluster binding
ES967_05165	COG0668	transmembrane transport
ES967_05170	COG2719	SpoVR family
ES967_05175	COG1785	Belongs to the alkaline phosphatase family
ES967_05180	COG0791	NLP P60 protein
ES967_05180	COG1388	LysM domain
ES967_05185	COG0583	DNA-binding transcription factor activity
ES967_05190	COG0372	Belongs to the citrate synthase family
ES967_05195	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_05200	COG0531	amino acid
ES967_05205	COG0733	neurotransmitter:sodium symporter activity
ES967_05210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ES967_05215	COG0456	acetyltransferase
ES967_05230	COG1595	DNA-templated transcription, initiation
ES967_05235	COG0667	Aldo Keto reductase
ES967_05240	COG0204	Acyl-transferase
ES967_05245	COG1253	flavin adenine dinucleotide binding
ES967_05250	COG0789	Transcriptional regulator
ES967_05255	COG0436	Aminotransferase
ES967_05260	COG1253	flavin adenine dinucleotide binding
ES967_05265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ES967_05270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ES967_05275	COG0584	glycerophosphoryl diester phosphodiesterase
ES967_05285	COG0668	transmembrane transport
ES967_05290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ES967_05295	COG0726	polysaccharide deacetylase
ES967_05300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ES967_05305	COG1757	Na H antiporter
ES967_05310	COG0589	response to stress
ES967_05320	COG1132	(ABC) transporter
ES967_05325	COG1132	(ABC) transporter
ES967_05330	COG0702	epimerase
ES967_05350	COG0189	ligase activity
ES967_05355	COG0189	ligase activity
ES967_05360	COG4399	Belongs to the UPF0754 family
ES967_05365	COG3679	Belongs to the UPF0342 family
ES967_05370	COG4335	DNA alkylation repair
ES967_05375	COG0561	phosphatase activity
ES967_05380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ES967_05385	COG0475	glutathione-regulated potassium exporter activity
ES967_05390	COG0490	domain, Protein
ES967_05400	COG1024	Enoyl-CoA hydratase
ES967_05410	COG4152	abc transporter atp-binding protein
ES967_05415	COG1668	transmembrane transport
ES967_05420	COG0420	3'-5' exonuclease activity
ES967_05425	COG4717	serine-type aminopeptidase activity
ES967_05430	COG3481	metal-dependent phosphohydrolase, HD sub domain
ES967_05440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ES967_05470	COG1846	Transcriptional regulator
ES967_05475	COG4980	gas vesicle protein
ES967_05490	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ES967_05495	COG0537	adenosine 5'-monophosphoramidase activity
ES967_05500	COG1131	(ABC) transporter
ES967_05505	COG4473	ABC transporter
ES967_05515	COG1473	amidohydrolase
ES967_05520	COG3069	C4-dicarboxylate transmembrane transporter activity
ES967_05530	COG2329	Antibiotic biosynthesis monooxygenase
ES967_05535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ES967_05540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ES967_05555	COG1309	transcriptional regulator
ES967_05560	COG1511	domain protein
ES967_05565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ES967_05570	COG4377	Putative membrane peptidase family (DUF2324)
ES967_05580	COG1363	Peptidase, m42
ES967_05585	COG4405	Protein conserved in bacteria
ES967_05590	COG1301	dicarboxylic acid transport
ES967_05600	COG1234	tRNA 3'-trailer cleavage
ES967_05605	COG0095	Lipoate-protein ligase
ES967_05610	COG0702	epimerase
ES967_05615	COG0318	PFAM AMP-dependent synthetase and ligase
ES967_05625	COG0501	Belongs to the peptidase M48B family
ES967_05630	COG1404	Belongs to the peptidase S8 family
ES967_05635	COG0456	acetyltransferase
ES967_05640	COG0604	alcohol dehydrogenase
ES967_05645	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ES967_05650	COG0406	alpha-ribazole phosphatase activity
ES967_05655	COG0183	Belongs to the thiolase family
ES967_05660	COG0318	PFAM AMP-dependent synthetase and ligase
ES967_05665	COG1268	BioY protein
ES967_05670	COG0840	transmembrane signaling receptor activity
ES967_05675	COG0723	plastoquinol--plastocyanin reductase activity
ES967_05675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ES967_05680	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_05690	COG4903	ComK protein
ES967_05695	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_05705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ES967_05720	COG0398	Pfam SNARE associated Golgi protein
ES967_05725	COG0681	Belongs to the peptidase S26 family
ES967_05730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ES967_05735	COG1846	Transcriptional regulator
ES967_05740	COG0738	Major facilitator superfamily
ES967_05745	COG0673	inositol 2-dehydrogenase activity
ES967_05750	COG0561	phosphatase activity
ES967_05755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ES967_05760	COG1609	Transcriptional regulator
ES967_05765	COG3180	Ammonia monooxygenase
ES967_05770	COG2814	Major facilitator Superfamily
ES967_05770	COG0477	Major facilitator Superfamily
ES967_05775	COG4533	DNA binding
ES967_05785	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ES967_05790	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ES967_05795	COG1074	ATP-dependent DNA helicase activity
ES967_05800	COG0420	3'-5' exonuclease activity
ES967_05805	COG0419	ATPase involved in DNA repair
ES967_05810	COG1403	HNH endonuclease
ES967_05850	COG5337	Spore coat protein CotH
ES967_05855	COG0179	Fumarylacetoacetate (FAA) hydrolase
ES967_05865	COG1404	Belongs to the peptidase S8 family
ES967_05875	COG0367	asparagine synthase
ES967_05880	COG2318	DinB family
ES967_05885	COG1562	ergosterol biosynthetic process
ES967_05890	COG0534	Mate efflux family protein
ES967_05895	COG1917	Cupin 2, conserved barrel domain protein
ES967_05895	COG2207	Transcriptional regulator
ES967_05900	COG1609	Transcriptional regulator
ES967_05905	COG0673	inositol 2-dehydrogenase activity
ES967_05910	COG2318	DinB family
ES967_05915	COG1279	arginine transmembrane transporter activity
ES967_05920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ES967_05925	COG1357	PFAM Pentapeptide repeats (8 copies)
ES967_05930	COG2267	carboxylic ester hydrolase activity
ES967_05935	COG0529	Catalyzes the synthesis of activated sulfate
ES967_05940	COG2046	Belongs to the sulfate adenylyltransferase family
ES967_05945	COG0175	sulfate reduction
ES967_05950	COG2045	Belongs to the ComB family
ES967_05955	COG1809	phosphosulfolactate synthase activity
ES967_05960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ES967_05965	COG4948	Mandelate Racemase Muconate Lactonizing
ES967_05970	COG2814	Major facilitator Superfamily
ES967_05975	COG0454	-acetyltransferase
ES967_05980	COG2153	protein acetylation
ES967_05985	COG0646	methionine synthase
ES967_05985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ES967_05990	COG1666	GTP binding
ES967_05995	COG2996	Protein conserved in bacteria
ES967_06015	COG1695	Transcriptional regulator
ES967_06030	COG3227	Zinc metalloprotease (Elastase)
ES967_06035	COG1307	EDD domain protein, DegV family
ES967_06040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ES967_06055	COG0561	phosphatase activity
ES967_06060	COG1073	alpha beta
ES967_06065	COG2151	metal-sulfur cluster biosynthetic enzyme
ES967_06075	COG0277	FAD linked oxidase domain protein
ES967_06080	COG2271	Major facilitator Superfamily
ES967_06085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ES967_06100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ES967_06105	COG0505	Belongs to the CarA family
ES967_06110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ES967_06115	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ES967_06130	COG2267	carboxylic ester hydrolase activity
ES967_06140	COG1744	ABC transporter substrate-binding protein PnrA-like
ES967_06155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ES967_06160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ES967_06165	COG5504	Zn-dependent protease
ES967_06170	COG0444	Belongs to the ABC transporter superfamily
ES967_06175	COG4608	Belongs to the ABC transporter superfamily
ES967_06185	COG0601	transmembrane transport
ES967_06190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ES967_06200	COG0180	Tryptophanyl-tRNA synthetase
ES967_06205	COG4166	transmembrane transport
ES967_06210	COG0601	transmembrane transport
ES967_06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ES967_06220	COG0444	Belongs to the ABC transporter superfamily
ES967_06225	COG4608	Belongs to the ABC transporter superfamily
ES967_06230	COG2814	Major facilitator Superfamily
ES967_06235	COG0456	acetyltransferase
ES967_06240	COG1393	Belongs to the ArsC family
ES967_06245	COG0861	Integral membrane protein TerC family
ES967_06255	COG4862	establishment of competence for transformation
ES967_06265	COG4469	Competence protein
ES967_06270	COG1164	Oligoendopeptidase f
ES967_06290	COG2346	COG2346, Truncated hemoglobins
ES967_06295	COG0741	lytic transglycosylase activity
ES967_06300	COG4116	CYTH
ES967_06310	COG2357	RelA SpoT domain protein
ES967_06315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ES967_06320	COG0564	pseudouridine synthase activity
ES967_06325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ES967_06330	COG0569	domain protein
ES967_06330	COG0475	glutathione-regulated potassium exporter activity
ES967_06335	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ES967_06340	COG0352	thiamine-phosphate diphosphorylase activity
ES967_06345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ES967_06350	COG2104	thiamine diphosphate biosynthetic process
ES967_06355	COG2022	thiamine diphosphate biosynthetic process
ES967_06360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ES967_06365	COG0351	phosphomethylpyrimidine kinase
ES967_06370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ES967_06425	COG0210	DNA helicase
ES967_06435	COG2153	protein acetylation
ES967_06440	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ES967_06445	COG2382	esterase
ES967_06450	COG0626	cystathionine gamma-synthase activity
ES967_06455	COG0626	cystathionine gamma-synthase activity
ES967_06460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES967_06465	COG5505	Protein of unknown function (DUF819)
ES967_06495	COG3677	Transposase
ES967_06510	COG5484	DNA packaging
ES967_06515	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ES967_06520	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_06530	COG3711	transcriptional antiterminator
ES967_06530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES967_06535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES967_06535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ES967_06535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ES967_06540	COG1482	cell wall glycoprotein biosynthetic process
ES967_06550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES967_06560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ES967_06580	COG0109	protoheme IX farnesyltransferase activity
ES967_06590	COG0726	polysaccharide deacetylase
ES967_06605	COG5504	Zn-dependent protease
ES967_06610	COG2205	protein histidine kinase activity
ES967_06620	COG3383	formate dehydrogenase (NAD+) activity
ES967_06625	COG2427	Protein of unknown function (DUF1641)
ES967_06635	COG1051	belongs to the nudix hydrolase family
ES967_06645	COG2124	cytochrome p450
ES967_06650	COG1819	glycosyl
ES967_06660	COG1587	Uroporphyrinogen-III synthase
ES967_06665	COG0390	transport system, permease component
ES967_06670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ES967_06675	COG0697	spore germination
ES967_06680	COG4297	protein containing double-stranded beta helix domain
ES967_06690	COG1252	NADH dehydrogenase
ES967_06695	COG1904	glucuronate isomerase
ES967_06700	COG2211	Major facilitator Superfamily
ES967_06705	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ES967_06710	COG1063	alcohol dehydrogenase
ES967_06715	COG1312	Catalyzes the dehydration of D-mannonate
ES967_06720	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_06725	COG2271	Major facilitator Superfamily
ES967_06730	COG1609	Transcriptional regulator
ES967_06735	COG0246	Mannitol dehydrogenase
ES967_06740	COG2721	sulfolactate sulfo-lyase activity
ES967_06745	COG0730	response to heat
ES967_06750	COG2318	DinB family
ES967_06755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ES967_06760	COG0457	Tetratricopeptide repeat
ES967_06770	COG2350	Protein conserved in bacteria
ES967_06775	COG5632	N-Acetylmuramoyl-L-alanine amidase
ES967_06775	COG3409	Peptidoglycan-binding domain 1 protein
ES967_06775	COG1388	LysM domain
ES967_06785	COG4195	phage-related replication protein
ES967_06790	COG3546	catalase activity
ES967_06795	COG2856	Zn peptidase
ES967_06800	COG1396	sequence-specific DNA binding
ES967_06810	COG1522	sequence-specific DNA binding
ES967_06815	COG1484	DNA-dependent DNA replication
ES967_06835	COG1595	DNA-templated transcription, initiation
ES967_06840	COG3728	DNA packaging
ES967_06840	COG5484	DNA packaging
ES967_06845	COG1783	phage Terminase large subunit
ES967_06850	COG5518	Phage portal protein
ES967_06855	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ES967_06860	COG4653	Phage capsid family
ES967_06910	COG5412	phage tail tape measure protein
ES967_06910	COG3953	SLT domain
ES967_06915	COG1652	LysM domain
ES967_06920	COG4193	domain, Protein
ES967_06930	COG3628	GPW Gp25 family protein
ES967_06935	COG3299	homolog of phage Mu protein gp47
ES967_06940	COG3778	Protein conserved in bacteria
ES967_06980	COG3409	Peptidoglycan-binding domain 1 protein
ES967_06980	COG5632	N-Acetylmuramoyl-L-alanine amidase
ES967_07000	COG0306	phosphate transporter
ES967_07005	COG1392	Phosphate transport regulator
ES967_07010	COG0531	amino acid
ES967_07015	COG0346	lactoylglutathione lyase activity
ES967_07025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ES967_07030	COG0463	Glycosyl transferase, family 2
ES967_07035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ES967_07040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ES967_07045	COG2362	D-Aminopeptidase
ES967_07050	COG0601	transmembrane transport
ES967_07055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ES967_07060	COG0444	Belongs to the ABC transporter superfamily
ES967_07065	COG4166	transmembrane transport
ES967_07070	COG1619	proteins homologs of microcin C7 resistance protein MccF
ES967_07075	COG4948	Mandelate Racemase Muconate Lactonizing
ES967_07080	COG0791	NLP P60 protein
ES967_07085	COG4608	Belongs to the ABC transporter superfamily
ES967_07090	COG2706	6-phosphogluconolactonase activity
ES967_07095	COG1834	amidinotransferase
ES967_07100	COG1607	acyl-coa hydrolase
ES967_07105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ES967_07105	COG1017	nitric oxide dioxygenase activity
ES967_07115	COG2323	membrane
ES967_07120	COG2318	DinB family
ES967_07125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES967_07130	COG2076	Multidrug Resistance protein
ES967_07135	COG2076	Multidrug Resistance protein
ES967_07140	COG0788	formyltetrahydrofolate deformylase activity
ES967_07145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ES967_07150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ES967_07155	COG1764	response to oxidative stress
ES967_07160	COG1846	Transcriptional regulator
ES967_07165	COG1764	response to oxidative stress
ES967_07175	COG0590	tRNA wobble adenosine to inosine editing
ES967_07180	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ES967_07185	COG1404	Belongs to the peptidase S8 family
ES967_07190	COG1366	Belongs to the anti-sigma-factor antagonist family
ES967_07195	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ES967_07200	COG1122	ATPase activity
ES967_07205	COG4721	ABC-type cobalt transport system, permease component
ES967_07215	COG0745	RESPONSE REGULATOR receiver
ES967_07220	COG5002	protein histidine kinase activity
ES967_07220	COG3850	Histidine kinase
ES967_07225	COG3212	peptidase
ES967_07230	COG3212	peptidase
ES967_07245	COG2239	Acts as a magnesium transporter
ES967_07250	COG0789	Transcriptional regulator
ES967_07265	COG1846	Transcriptional regulator
ES967_07275	COG0726	polysaccharide deacetylase
ES967_07280	COG1408	metallophosphoesterase
ES967_07290	COG0463	Glycosyl transferase, family 2
ES967_07295	COG3285	dna ligase
ES967_07295	COG1793	dna ligase
ES967_07300	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ES967_07305	COG5001	Diguanylate cyclase
ES967_07305	COG3300	MHYT domain
ES967_07310	COG0586	Pfam SNARE associated Golgi protein
ES967_07315	COG0861	Integral membrane protein TerC family
ES967_07320	COG1191	sigma factor activity
ES967_07340	COG0501	Belongs to the peptidase M48B family
ES967_07345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ES967_07360	COG3594	Acyltransferase
ES967_07365	COG5002	protein histidine kinase activity
ES967_07370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ES967_07380	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ES967_07385	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ES967_07390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ES967_07395	COG0436	Aminotransferase
ES967_07400	COG1850	ribulose-bisphosphate carboxylase activity
ES967_07405	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ES967_07410	COG0235	Class ii aldolase
ES967_07415	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ES967_07420	COG3339	Conserved Protein
ES967_07435	COG3852	Histidine kinase
ES967_07445	COG1846	Transcriptional regulator
ES967_07450	COG1360	Flagellar Motor Protein
ES967_07455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ES967_07465	COG0542	response to heat
ES967_07470	COG3949	Membrane
ES967_07475	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ES967_07480	COG0720	synthase
ES967_07485	COG0602	queuosine metabolic process
ES967_07490	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ES967_07495	COG1733	regulation of RNA biosynthetic process
ES967_07500	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_07505	COG1388	LysM domain
ES967_07505	COG4641	Protein conserved in bacteria
ES967_07510	COG1388	LysM domain
ES967_07515	COG3858	chitin binding
ES967_07525	COG4873	Protein conserved in bacteria
ES967_07535	COG3773	Cell wall hydrolase
ES967_07540	COG2244	polysaccharide biosynthetic process
ES967_07545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES967_07550	COG2217	Heavy metal translocating P-type atpase
ES967_07560	COG0006	proline dipeptidase activity
ES967_07565	COG1609	Transcriptional regulator
ES967_07570	COG3711	transcriptional antiterminator
ES967_07575	COG2190	(PTS) system
ES967_07575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_07575	COG1263	PTS System
ES967_07580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES967_07585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ES967_07595	COG1533	DNA photolyase activity
ES967_07600	COG0456	acetyltransferase
ES967_07605	COG0840	transmembrane signaling receptor activity
ES967_07610	COG2084	Dehydrogenase
ES967_07615	COG2340	Cysteine-rich secretory protein family
ES967_07620	COG0768	penicillin binding
ES967_07625	COG4191	Histidine kinase
ES967_07630	COG0436	Aminotransferase
ES967_07640	COG0784	Response regulator, receiver
ES967_07640	COG0835	chemotaxis
ES967_07650	COG2814	Major facilitator Superfamily
ES967_07655	COG1376	ErfK ybiS ycfS ynhG family protein
ES967_07660	COG1408	metallophosphoesterase
ES967_07665	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_07670	COG3409	Peptidoglycan-binding domain 1 protein
ES967_07680	COG2200	EAL domain
ES967_07685	COG4703	Protein of unknown function (DUF1797)
ES967_07690	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ES967_07700	COG0517	IMP dehydrogenase activity
ES967_07705	COG0583	DNA-binding transcription factor activity
ES967_07710	COG0716	FMN binding
ES967_07720	COG0716	FMN binding
ES967_07725	COG2171	N-acyltransferase activity
ES967_07730	COG1473	amidohydrolase
ES967_07740	COG0668	transmembrane transport
ES967_07745	COG0450	alkyl hydroperoxide reductase
ES967_07750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES967_07765	COG0746	molybdenum cofactor guanylyltransferase activity
ES967_07770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ES967_07775	COG0303	'Molybdopterin
ES967_07780	COG1763	Mo-molybdopterin cofactor biosynthetic process
ES967_07785	COG0314	molybdopterin synthase activity
ES967_07790	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ES967_07795	COG1132	(ABC) transporter
ES967_07800	COG1132	(ABC) transporter
ES967_07810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ES967_07815	COG1136	(ABC) transporter
ES967_07820	COG0577	efflux transmembrane transporter activity
ES967_07825	COG1349	DNA-binding transcription factor activity
ES967_07830	COG1105	Belongs to the carbohydrate kinase PfkB family
ES967_07835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ES967_07835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ES967_07835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES967_07840	COG0681	Belongs to the peptidase S26 family
ES967_07850	COG0488	(ABC) transporter
ES967_07855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ES967_07860	COG2309	aminopeptidase activity
ES967_07870	COG1077	Cell shape determining protein MreB Mrl
ES967_07875	COG2002	toxin-antitoxin pair type II binding
ES967_07880	COG3852	Histidine kinase
ES967_07885	COG2105	PFAM AIG2 family protein
ES967_07885	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ES967_07890	COG0569	domain protein
ES967_07895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ES967_07900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ES967_07910	COG0561	phosphatase activity
ES967_07915	COG0242	peptide deformylase activity
ES967_07925	COG0497	DNA recombination
ES967_07930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ES967_07935	COG0022	dehydrogenase e1 component
ES967_07940	COG0508	dehydrogenase complex catalyzes the overall conversion of
ES967_07945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ES967_07950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES967_07960	COG1982	Orn Lys Arg decarboxylase major
ES967_07965	COG4476	Belongs to the UPF0223 family
ES967_07970	COG4493	Belongs to the UPF0637 family
ES967_07980	COG0483	inositol monophosphate 1-phosphatase activity
ES967_07990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ES967_08010	COG1595	DNA-templated transcription, initiation
ES967_08040	COG4896	Protein conserved in bacteria
ES967_08050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ES967_08055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ES967_08060	COG2066	Belongs to the glutaminase family
ES967_08065	COG4838	Belongs to the UPF0358 family
ES967_08070	COG0772	Belongs to the SEDS family
ES967_08075	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ES967_08080	COG1612	heme a metabolic process
ES967_08085	COG0109	protoheme IX farnesyltransferase activity
ES967_08090	COG2010	Cytochrome c
ES967_08090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ES967_08095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ES967_08100	COG1845	cytochrome c oxidase, subunit III
ES967_08105	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ES967_08110	COG3336	cytochrome c oxidase
ES967_08120	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ES967_08125	COG2340	Cysteine-rich secretory protein family
ES967_08140	COG3679	Belongs to the UPF0342 family
ES967_08145	COG4471	UPF0298 protein
ES967_08150	COG0742	ribosomal rna small subunit methyltransferase
ES967_08155	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ES967_08160	COG3314	Sporulation integral membrane protein YlbJ
ES967_08165	COG1752	Esterase of the alpha-beta hydrolase superfamily
ES967_08170	COG3480	Lon protease (S16) C-terminal proteolytic domain
ES967_08175	COG1323	Belongs to the UPF0348 family
ES967_08185	COG1399	metal-binding, possibly nucleic acid-binding protein
ES967_08190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ES967_08200	COG0454	-acetyltransferase
ES967_08205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ES967_08210	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ES967_08215	COG2001	Belongs to the MraZ family
ES967_08220	COG0275	rRNA processing
ES967_08225	COG4839	cell division protein FtsL
ES967_08235	COG0768	penicillin binding
ES967_08240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ES967_08245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ES967_08250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ES967_08255	COG0772	Belongs to the SEDS family
ES967_08260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ES967_08265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ES967_08270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ES967_08275	COG3879	Bacterial protein of unknown function (DUF881)
ES967_08280	COG3879	Bacterial protein of unknown function (DUF881)
ES967_08285	COG3856	small basic protein
ES967_08290	COG0849	cell division
ES967_08295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ES967_08300	COG4412	M6 family metalloprotease domain protein
ES967_08300	COG1404	Belongs to the peptidase S8 family
ES967_08310	COG1191	sigma factor activity
ES967_08315	COG1191	sigma factor activity
ES967_08320	COG1119	ATPase activity
ES967_08325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ES967_08330	COG1873	PFAM PRC-barrel domain
ES967_08340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ES967_08345	COG1799	cell septum assembly
ES967_08350	COG0762	integral membrane protein
ES967_08355	COG2302	S4 RNA-binding domain
ES967_08360	COG3599	regulation of cell shape
ES967_08365	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ES967_08370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ES967_08375	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ES967_08380	COG0564	pseudouridine synthase activity
ES967_08385	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ES967_08390	COG2233	PERMEase
ES967_08395	COG0540	Belongs to the ATCase OTCase family
ES967_08400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ES967_08405	COG0505	Belongs to the CarA family
ES967_08410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ES967_08415	COG0543	2 iron, 2 sulfur cluster binding
ES967_08420	COG0167	dihydroorotate dehydrogenase activity
ES967_08425	COG0284	orotidine-5'-phosphate decarboxylase activity
ES967_08430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ES967_08435	COG0175	sulfate reduction
ES967_08440	COG0306	phosphate transporter
ES967_08445	COG2046	Belongs to the sulfate adenylyltransferase family
ES967_08450	COG0529	Catalyzes the synthesis of activated sulfate
ES967_08455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ES967_08460	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
ES967_08465	COG1648	precorrin-2 dehydrogenase activity
ES967_08475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ES967_08480	COG1561	YicC-like family, N-terminal region
ES967_08485	COG2052	Domain of unknown function (DUF370)
ES967_08490	COG0194	GDP metabolic process
ES967_08495	COG1758	RNA polymerase activity
ES967_08500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ES967_08505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ES967_08510	COG0242	peptide deformylase activity
ES967_08515	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ES967_08520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ES967_08520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ES967_08525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ES967_08530	COG0631	protein serine/threonine phosphatase activity
ES967_08535	COG2815	serine threonine protein kinase
ES967_08535	COG0515	serine threonine protein kinase
ES967_08540	COG1162	GTPase activity
ES967_08545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ES967_08550	COG1564	THIamine pyrophosphokinase
ES967_08560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ES967_08565	COG1302	Protein conserved in bacteria
ES967_08570	COG1461	Dihydroxyacetone kinase
ES967_08575	COG1760	l-serine dehydratase
ES967_08580	COG1760	l-serine dehydratase
ES967_08585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ES967_08590	COG1349	DNA-binding transcription factor activity
ES967_08590	COG2050	protein possibly involved in aromatic compounds catabolism
ES967_08595	COG0416	fatty acid biosynthetic process
ES967_08600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ES967_08605	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_08610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ES967_08615	COG0571	ribonuclease III activity
ES967_08620	COG1196	nuclear chromosome segregation
ES967_08625	COG0552	protein localization to endoplasmic reticulum
ES967_08635	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ES967_08640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ES967_08645	COG0228	four-way junction DNA binding
ES967_08650	COG1837	Belongs to the UPF0109 family
ES967_08660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ES967_08665	COG0336	Belongs to the RNA methyltransferase TrmD family
ES967_08670	COG0335	large ribosomal subunit rRNA binding
ES967_08675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ES967_08680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ES967_08690	COG2257	FlhB HrpN YscU SpaS Family
ES967_08695	COG0045	succinate-CoA ligase (ADP-forming) activity
ES967_08700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ES967_08705	COG0758	DNA mediated transformation
ES967_08710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ES967_08715	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ES967_08720	COG4974	Belongs to the 'phage' integrase family
ES967_08725	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ES967_08730	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ES967_08735	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ES967_08740	COG1815	bacterial-type flagellum-dependent cell motility
ES967_08745	COG1558	bacterial-type flagellum-dependent cell motility
ES967_08750	COG1677	Flagellar hook-basal body complex protein FliE
ES967_08755	COG1766	The M ring may be actively involved in energy transduction
ES967_08760	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ES967_08765	COG1317	bacterial-type flagellum organization
ES967_08770	COG1157	protein secretion by the type III secretion system
ES967_08775	COG2882	bacterial-type flagellum organization
ES967_08780	COG3334	PFAM MgtE intracellular
ES967_08785	COG3144	bacterial-type flagellum assembly
ES967_08790	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ES967_08795	COG4786	Flagellar basal body rod
ES967_08800	COG1582	Flagellar protein (FlbD)
ES967_08805	COG1580	Controls the rotational direction of flagella during chemotaxis
ES967_08810	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ES967_08815	COG1776	CheC inhibitor of MCP methylation
ES967_08815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ES967_08820	COG2201	protein-glutamate methylesterase activity
ES967_08825	COG3190	flagellar
ES967_08830	COG1338	Plays a role in the flagellum-specific transport system
ES967_08835	COG1987	bacterial-type flagellum assembly
ES967_08840	COG1684	flagellar biosynthetic protein fliR
ES967_08845	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ES967_08850	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ES967_08855	COG1419	protein localization to endoplasmic reticulum
ES967_08860	COG0455	bacterial-type flagellum organization
ES967_08865	COG2201	protein-glutamate methylesterase activity
ES967_08870	COG2198	Histidine kinase
ES967_08870	COG0643	Histidine kinase
ES967_08875	COG0835	chemotaxis
ES967_08880	COG1776	CheC inhibitor of MCP methylation
ES967_08885	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ES967_08890	COG1191	sigma factor activity
ES967_08900	COG0052	Belongs to the universal ribosomal protein uS2 family
ES967_08905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ES967_08910	COG0528	UMP kinase activity
ES967_08915	COG0233	cytoplasmic translational termination
ES967_08920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ES967_08925	COG4589	Belongs to the CDS family
ES967_08930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ES967_08935	COG0750	zinc metalloprotease
ES967_08940	COG0442	prolyl-tRNA aminoacylation
ES967_08945	COG2176	DNA-directed DNA polymerase activity
ES967_08950	COG0779	Required for maturation of 30S ribosomal subunits
ES967_08955	COG0195	Participates in both transcription termination and antitermination
ES967_08960	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ES967_08965	COG1358	cellular component organization or biogenesis
ES967_08970	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ES967_08975	COG1550	Protein conserved in bacteria
ES967_08980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ES967_08985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ES967_08990	COG0196	riboflavin kinase activity
ES967_08995	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ES967_09000	COG1185	polyribonucleotide nucleotidyltransferase activity
ES967_09005	COG0726	polysaccharide deacetylase
ES967_09010	COG0612	Peptidase, M16
ES967_09015	COG1873	PFAM PRC-barrel domain
ES967_09020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ES967_09025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ES967_09030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ES967_09035	COG0527	aspartate kinase activity
ES967_09040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ES967_09045	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ES967_09050	COG0740	serine-type endopeptidase activity
ES967_09060	COG1674	ftsk spoiiie
ES967_09060	COG4980	gas vesicle protein
ES967_09065	COG2188	Transcriptional regulator
ES967_09070	COG2814	Major facilitator Superfamily
ES967_09075	COG0612	Peptidase, M16
ES967_09080	COG0612	Peptidase, M16
ES967_09085	COG0300	oxidoreductase activity
ES967_09100	COG1426	Protein conserved in bacteria
ES967_09105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ES967_09110	COG1546	Belongs to the CinA family
ES967_09110	COG1058	Belongs to the CinA family
ES967_09115	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ES967_09120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ES967_09125	COG1418	mRNA catabolic process
ES967_09130	COG1692	metallophosphoesterase
ES967_09135	COG2359	stage V sporulation protein S
ES967_09140	COG1063	alcohol dehydrogenase
ES967_09145	COG0156	8-amino-7-oxononanoate synthase activity
ES967_09150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ES967_09155	COG4550	Control of competence regulator ComK, YlbF/YmcA
ES967_09165	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ES967_09170	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ES967_09185	COG3226	Transcriptional regulator
ES967_09190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ES967_09200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ES967_09205	COG3321	synthase
ES967_09210	COG2070	2-Nitropropane dioxygenase
ES967_09210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ES967_09215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ES967_09220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ES967_09225	COG3425	synthase
ES967_09230	COG1024	Enoyl-CoA hydratase
ES967_09235	COG1024	Enoyl-CoA hydratase
ES967_09240	COG0318	PFAM AMP-dependent synthetase and ligase
ES967_09240	COG3321	synthase
ES967_09240	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_09240	COG0300	oxidoreductase activity
ES967_09240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_09245	COG3321	synthase
ES967_09245	COG4221	oxidoreductase activity
ES967_09245	COG0300	oxidoreductase activity
ES967_09245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ES967_09250	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_09250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_09250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ES967_09250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ES967_09250	COG3321	synthase
ES967_09255	COG3321	synthase
ES967_09255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_09255	COG4221	oxidoreductase activity
ES967_09255	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_09260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ES967_09260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ES967_09260	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ES967_09260	COG3321	synthase
ES967_09265	COG2124	cytochrome p450
ES967_09275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ES967_09280	COG1404	Belongs to the peptidase S8 family
ES967_09290	COG4195	phage-related replication protein
ES967_09295	COG1764	response to oxidative stress
ES967_09300	COG2076	Multidrug Resistance protein
ES967_09305	COG2076	Multidrug Resistance protein
ES967_09320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ES967_09325	COG1923	regulation of RNA biosynthetic process
ES967_09340	COG1780	Probably involved in ribonucleotide reductase function
ES967_09345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ES967_09350	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ES967_09355	COG4112	unkown
ES967_09360	COG0860	N-Acetylmuramoyl-L-alanine amidase
ES967_09370	COG0464	growth
ES967_09375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ES967_09380	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ES967_09385	COG0789	Transcriptional regulator
ES967_09390	COG0174	glutamine synthetase
ES967_09410	COG4282	regulation of fungal-type cell wall biogenesis
ES967_09420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES967_09450	COG0135	phosphoribosylanthranilate isomerase activity
ES967_09455	COG2211	Major facilitator Superfamily
ES967_09460	COG3507	Belongs to the glycosyl hydrolase 43 family
ES967_09465	COG1940	carbohydrate kinase activity
ES967_09470	COG2115	Belongs to the xylose isomerase family
ES967_09475	COG1070	Carbohydrate kinase
ES967_09485	COG1525	nuclease
ES967_09490	COG2814	Major facilitator Superfamily
ES967_09495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ES967_09505	COG0756	dUTP diphosphatase activity
ES967_09520	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ES967_09545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ES967_09560	COG3832	glyoxalase III activity
ES967_09575	COG0697	spore germination
ES967_09580	COG0531	amino acid
ES967_09610	COG4195	phage-related replication protein
ES967_09620	COG0346	lactoylglutathione lyase activity
ES967_09630	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ES967_09635	COG1388	LysM domain
ES967_09640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ES967_09645	COG4224	UPF0291 protein
ES967_09650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ES967_09660	COG3763	UPF0154 protein
ES967_09670	COG0785	Cytochrome C biogenesis protein
ES967_09675	COG2201	protein-glutamate methylesterase activity
ES967_09680	COG4846	Membrane protein involved in cytochrome C biogenesis
ES967_09690	COG0071	Belongs to the small heat shock protein (HSP20) family
ES967_09705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ES967_09710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES967_09730	COG0824	Thioesterase
ES967_09740	COG4841	protein insertion into membrane
ES967_09745	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ES967_09750	COG1832	CoA-binding protein
ES967_09755	COG0187	DNA topoisomerase II activity
ES967_09760	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ES967_09770	COG1115	amino acid carrier protein
ES967_09775	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ES967_09785	COG5520	Belongs to the glycosyl hydrolase 30 family
ES967_09790	COG3507	Belongs to the glycosyl hydrolase 43 family
ES967_09800	COG2246	polysaccharide biosynthetic process
ES967_09805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ES967_09810	COG0586	Pfam SNARE associated Golgi protein
ES967_09815	COG2404	hydrolase activity, acting on ester bonds
ES967_09820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ES967_09825	COG1024	Enoyl-CoA hydratase
ES967_09830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ES967_09835	COG0511	ligase activity, forming carbon-carbon bonds
ES967_09840	COG0439	Biotin carboxylase
ES967_09845	COG0318	PFAM AMP-dependent synthetase and ligase
ES967_09850	COG1960	acyl-CoA dehydrogenase activity
ES967_09865	COG1649	PFAM Uncharacterised BCR, COG1649
ES967_09875	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ES967_09875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_09880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_09885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_09890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_09895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_09900	COG2027	D-alanyl-D-alanine carboxypeptidase
ES967_09905	COG2017	converts alpha-aldose to the beta-anomer
ES967_09910	COG0534	Mate efflux family protein
ES967_09925	COG0582	viral genome integration into host DNA
ES967_09930	COG0166	Belongs to the GPI family
ES967_09935	COG0405	Gamma-glutamyltransferase
ES967_09940	COG0583	DNA-binding transcription factor activity
ES967_09945	COG0604	alcohol dehydrogenase
ES967_09950	COG0493	'glutamate synthase
ES967_09955	COG0069	glutamate synthase activity
ES967_09955	COG0070	glutamate synthase
ES967_09955	COG0067	glutamate synthase
ES967_09960	COG0583	DNA-binding transcription factor activity
ES967_09965	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ES967_09970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ES967_09980	COG0300	oxidoreductase activity
ES967_09985	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ES967_09995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES967_10010	COG1131	(ABC) transporter
ES967_10020	COG2814	Major facilitator Superfamily
ES967_10025	COG1070	Carbohydrate kinase
ES967_10030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ES967_10035	COG0243	molybdopterin cofactor binding
ES967_10065	COG0840	transmembrane signaling receptor activity
ES967_10065	COG5278	phosphoserine phosphatase activity
ES967_10070	COG2368	4-hydroxyphenylacetate
ES967_10075	COG4305	rare lipoprotein A
ES967_10080	COG3619	membrane
ES967_10085	COG3866	Pectate lyase
ES967_10090	COG2135	peptidase activity
ES967_10100	COG2140	Oxalate decarboxylase
ES967_10115	COG0456	acetyltransferase
ES967_10135	COG2720	vancomycin resistance protein
ES967_10145	COG3655	Transcriptional regulator
ES967_10150	COG3739	integral membrane protein
ES967_10155	COG0583	DNA-binding transcription factor activity
ES967_10160	COG0697	spore germination
ES967_10170	COG0693	protein deglycase activity
ES967_10175	COG2367	Beta-lactamase
ES967_10200	COG0574	Belongs to the PEP-utilizing enzyme family
ES967_10200	COG3848	Pyruvate phosphate dikinase
ES967_10205	COG0726	polysaccharide deacetylase
ES967_10215	COG2314	TM2 domain
ES967_10220	COG1396	sequence-specific DNA binding
ES967_10235	COG2135	peptidase activity
ES967_10275	COG0457	Tetratricopeptide repeat
ES967_10300	COG5290	Psort location Cytoplasmic, score
ES967_10325	COG5444	nuclease activity
ES967_10330	COG4282	regulation of fungal-type cell wall biogenesis
ES967_10335	COG1231	oxidoreductase activity
ES967_10340	COG5434	Belongs to the glycosyl hydrolase 28 family
ES967_10345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ES967_10350	COG2207	Transcriptional regulator
ES967_10350	COG0662	Cupin 2, conserved barrel domain protein
ES967_10355	COG0456	acetyltransferase
ES967_10360	COG1309	transcriptional regulator
ES967_10365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ES967_10370	COG3708	Transcriptional regulator
ES967_10375	COG2378	regulation of single-species biofilm formation
ES967_10385	COG0640	Transcriptional regulator
ES967_10390	COG0741	lytic transglycosylase activity
ES967_10395	COG2322	membrane
ES967_10410	COG1619	proteins homologs of microcin C7 resistance protein MccF
ES967_10415	COG3239	Fatty acid desaturase
ES967_10420	COG4585	Histidine kinase
ES967_10425	COG2197	response regulator
ES967_10430	COG3584	3D domain protein
ES967_10430	COG1388	LysM domain
ES967_10435	COG0514	ATP-dependent DNA helicase (RecQ)
ES967_10450	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ES967_10455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ES967_10470	COG0071	Belongs to the small heat shock protein (HSP20) family
ES967_10495	COG1012	belongs to the aldehyde dehydrogenase family
ES967_10500	COG1657	PFAM Prenyltransferase squalene oxidase
ES967_10505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ES967_10510	COG0733	neurotransmitter:sodium symporter activity
ES967_10515	COG0385	Bile acid
ES967_10520	COG0508	dehydrogenase complex catalyzes the overall conversion of
ES967_10525	COG0567	Dehydrogenase, E1 component
ES967_10530	COG4548	von Willebrand factor, type A
ES967_10535	COG0714	Associated with various cellular activities
ES967_10540	COG2032	superoxide dismutase activity
ES967_10545	COG0791	NLP P60 protein
ES967_10545	COG1388	LysM domain
ES967_10550	COG1819	glycosyl
ES967_10555	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ES967_10560	COG0534	Mate efflux family protein
ES967_10565	COG1366	Belongs to the anti-sigma-factor antagonist family
ES967_10570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ES967_10575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ES967_10585	COG2962	Rard protein
ES967_10600	COG2610	gluconate transmembrane transporter activity
ES967_10605	COG1942	4-Oxalocrotonate Tautomerase
ES967_10610	COG1733	regulation of RNA biosynthetic process
ES967_10615	COG0778	Nitroreductase
ES967_10620	COG0400	carboxylic ester hydrolase activity
ES967_10625	COG0346	lactoylglutathione lyase activity
ES967_10635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ES967_10640	COG0793	Belongs to the peptidase S41A family
ES967_10640	COG3409	Peptidoglycan-binding domain 1 protein
ES967_10645	COG2226	methyltransferase
ES967_10655	COG1876	peptidase activity
ES967_10660	COG0813	purine-nucleoside phosphorylase activity
ES967_10675	COG0671	phosphoesterase, PA-phosphatase related
ES967_10700	COG4479	Belongs to the UPF0346 family
ES967_10710	COG1509	lysine 2,3-aminomutase activity
ES967_10715	COG0456	acetyltransferase
ES967_10720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ES967_10725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ES967_10730	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ES967_10735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ES967_10750	COG0456	acetyltransferase
ES967_10755	COG0463	Glycosyl transferase, family 2
ES967_10770	COG4641	Protein conserved in bacteria
ES967_10775	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
ES967_10780	COG1086	Polysaccharide biosynthesis protein
ES967_10785	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ES967_10790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ES967_10795	COG1846	Transcriptional regulator
ES967_10800	COG0534	Mate efflux family protein
ES967_10810	COG4698	Protein conserved in bacteria
ES967_10815	COG2755	lipolytic protein G-D-S-L family
ES967_10820	COG1999	signal sequence binding
ES967_10830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ES967_10835	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ES967_10840	COG1272	protein, Hemolysin III
ES967_10845	COG0204	Acyl-transferase
ES967_10850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ES967_10855	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ES967_10860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ES967_10870	COG2521	methyltransferase
ES967_10870	COG2136	Putative SAM-dependent methyltransferase
ES967_10880	COG0129	dihydroxy-acid dehydratase activity
ES967_10885	COG1413	lyase activity
ES967_10890	COG1418	mRNA catabolic process
ES967_10895	COG0386	Belongs to the glutathione peroxidase family
ES967_10900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ES967_10905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ES967_10915	COG1278	Cold shock
ES967_10935	COG0328	RNA-DNA hybrid ribonuclease activity
ES967_10940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ES967_10945	COG0328	RNA-DNA hybrid ribonuclease activity
ES967_10955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ES967_10970	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ES967_10980	COG1755	Isoprenylcysteine carboxyl methyltransferase
ES967_10985	COG3424	synthase
ES967_10990	COG2233	PERMEase
ES967_10995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ES967_11000	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ES967_11010	COG0800	Aldolase
ES967_11015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ES967_11020	COG1609	Transcriptional regulator
ES967_11025	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ES967_11030	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_11035	COG1199	ATP-dependent helicase activity
ES967_11050	COG0116	Belongs to the methyltransferase superfamily
ES967_11065	COG4474	Belongs to the UPF0398 family
ES967_11080	COG3359	exonuclease
ES967_11085	COG1205	dead DEAH box helicase
ES967_11085	COG1111	helicase
ES967_11090	COG2190	(PTS) system
ES967_11095	COG0071	Belongs to the small heat shock protein (HSP20) family
ES967_11130	COG3331	DNA recombination
ES967_11135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ES967_11135	COG4499	WXG100 protein secretion system (Wss), protein YukC
ES967_11145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ES967_11150	COG3935	DnaD domain protein
ES967_11155	COG0017	Asparaginyl-tRNA synthetase
ES967_11160	COG0436	Aminotransferase
ES967_11165	COG5353	protein conserved in bacteria
ES967_11175	COG1199	ATP-dependent helicase activity
ES967_11175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ES967_11180	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ES967_11185	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ES967_11190	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ES967_11195	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ES967_11195	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ES967_11200	COG0617	tRNA 3'-terminal CCA addition
ES967_11205	COG0438	transferase activity, transferring glycosyl groups
ES967_11210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ES967_11215	COG1803	Methylglyoxal synthase
ES967_11220	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ES967_11225	COG1694	Mazg nucleotide pyrophosphohydrolase
ES967_11230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ES967_11240	COG4347	Protein of unknown function (DUF1405)
ES967_11245	COG2010	Cytochrome c
ES967_11245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ES967_11250	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ES967_11255	COG0723	plastoquinol--plastocyanin reductase activity
ES967_11265	COG5582	Belongs to the UPF0302 family
ES967_11270	COG0457	Tetratricopeptide repeat
ES967_11275	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ES967_11280	COG0287	Prephenate dehydrogenase
ES967_11285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ES967_11290	COG0159	tryptophan synthase activity
ES967_11295	COG0133	tryptophan synthase activity
ES967_11300	COG0135	phosphoribosylanthranilate isomerase activity
ES967_11310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ES967_11315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ES967_11320	COG4401	Chorismate mutase type I
ES967_11325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ES967_11330	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ES967_11335	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ES967_11340	COG0105	UTP biosynthetic process
ES967_11345	COG0142	geranyltranstransferase activity
ES967_11350	COG2226	methyltransferase
ES967_11355	COG0142	geranyltranstransferase activity
ES967_11365	COG0302	gtp cyclohydrolase
ES967_11370	COG0776	regulation of translation
ES967_11375	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ES967_11390	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ES967_11395	COG1160	GTP binding
ES967_11420	COG1304	FMN binding
ES967_11425	COG0539	negative regulation of cytoplasmic translation
ES967_11430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ES967_11440	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ES967_11445	COG2959	enzyme of heme biosynthesis
ES967_11450	COG3409	Peptidoglycan-binding domain 1 protein
ES967_11450	COG3773	Cell wall hydrolase
ES967_11455	COG2339	peptidase activity
ES967_11460	COG0492	ferredoxin-NADP+ reductase activity
ES967_11465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ES967_11470	COG4862	establishment of competence for transformation
ES967_11475	COG1408	metallophosphoesterase
ES967_11485	COG1388	LysM domain
ES967_11490	COG1266	CAAX protease self-immunity
ES967_11495	COG0514	ATP-dependent DNA helicase (RecQ)
ES967_11500	COG4955	Helix-turn-helix domain
ES967_11505	COG1141	Ferredoxin
ES967_11510	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ES967_11515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ES967_11520	COG0710	3-dehydroquinate dehydratase activity
ES967_11530	COG1595	DNA-templated transcription, initiation
ES967_11535	COG5002	protein histidine kinase activity
ES967_11540	COG0745	RESPONSE REGULATOR receiver
ES967_11545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ES967_11550	COG1333	cytochrome c biogenesis protein
ES967_11555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES967_11560	COG1187	pseudouridine synthase activity
ES967_11565	COG0700	Nucleoside recognition
ES967_11570	COG2715	membrane protein required for spore maturation
ES967_11575	COG1686	Belongs to the peptidase S11 family
ES967_11585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ES967_11590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ES967_11595	COG1547	Domain of unknown function (DUF309)
ES967_11600	COG0456	acetyltransferase
ES967_11605	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ES967_11610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ES967_11610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ES967_11615	COG0307	riboflavin synthase, alpha
ES967_11620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ES967_11620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ES967_11630	COG0681	Belongs to the peptidase S26 family
ES967_11635	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
ES967_11660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ES967_11670	COG4086	secreted protein
ES967_11675	COG0019	diaminopimelate decarboxylase activity
ES967_11680	COG0697	spore germination
ES967_11695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ES967_11715	COG1191	sigma factor activity
ES967_11720	COG2172	sigma factor antagonist activity
ES967_11725	COG1366	Belongs to the anti-sigma-factor antagonist family
ES967_11730	COG1686	Belongs to the peptidase S11 family
ES967_11735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ES967_11740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ES967_11745	COG4974	Belongs to the 'phage' integrase family
ES967_11755	COG0735	belongs to the Fur family
ES967_11760	COG1300	Membrane
ES967_11770	COG0281	malic enzyme
ES967_11775	COG1757	Na H antiporter
ES967_11780	COG1027	Aspartate ammonia-lyase
ES967_11785	COG0252	asparaginase activity
ES967_11790	COG1396	sequence-specific DNA binding
ES967_11795	COG1379	DNA repair
ES967_11800	COG0494	nUDIX hydrolase
ES967_11810	COG0667	Aldo Keto reductase
ES967_11820	COG1073	alpha beta
ES967_11830	COG4918	Iron-sulphur cluster biosynthesis
ES967_11835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ES967_11835	COG0456	acetyltransferase
ES967_11840	COG2329	Antibiotic biosynthesis monooxygenase
ES967_11845	COG0456	acetyltransferase
ES967_11855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ES967_11865	COG2211	Major facilitator Superfamily
ES967_11870	COG0346	lactoylglutathione lyase activity
ES967_11875	COG1072	(Pantothenic acid kinase))
ES967_11880	COG3048	D-serine ammonia-lyase activity
ES967_11885	COG0300	oxidoreductase activity
ES967_11890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ES967_11895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ES967_11900	COG4187	Peptidase family M20/M25/M40
ES967_11905	COG1902	pentaerythritol trinitrate reductase activity
ES967_11910	COG0596	Alpha beta hydrolase
ES967_11920	COG1234	tRNA 3'-trailer cleavage
ES967_11925	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ES967_11930	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ES967_11935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ES967_11945	COG0706	membrane insertase activity
ES967_11950	COG3361	conserved protein (COG2071)
ES967_11955	COG2195	Cleaves the N-terminal amino acid of tripeptides
ES967_11960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ES967_11965	COG0346	lactoylglutathione lyase activity
ES967_11970	COG1376	ErfK ybiS ycfS ynhG family protein
ES967_11975	COG4129	membrane
ES967_11980	COG1126	abc transporter atp-binding protein
ES967_11985	COG0765	amino acid transport
ES967_11990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES967_12000	COG1597	lipid kinase activity
ES967_12005	COG2814	Major facilitator Superfamily
ES967_12010	COG4978	Transcriptional regulator
ES967_12010	COG0789	Transcriptional regulator
ES967_12015	COG0508	dehydrogenase complex catalyzes the overall conversion of
ES967_12020	COG0022	dehydrogenase e1 component
ES967_12025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ES967_12030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ES967_12035	COG3426	butyrate kinase activity
ES967_12040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ES967_12045	COG0280	phosphate acetyltransferase
ES967_12050	COG3290	protein histidine kinase activity
ES967_12050	COG3829	transcription factor binding
ES967_12060	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ES967_12065	COG2079	MmgE PrpD family protein
ES967_12070	COG0372	Belongs to the citrate synthase family
ES967_12075	COG1960	acyl-CoA dehydrogenase activity
ES967_12080	COG1250	3-hydroxyacyl-CoA dehydrogenase
ES967_12085	COG0183	Belongs to the thiolase family
ES967_12090	COG0584	glycerophosphoryl diester phosphodiesterase
ES967_12095	COG0860	N-Acetylmuramoyl-L-alanine amidase
ES967_12110	COG1902	pentaerythritol trinitrate reductase activity
ES967_12115	COG0745	RESPONSE REGULATOR receiver
ES967_12120	COG0750	zinc metalloprotease
ES967_12125	COG0497	DNA recombination
ES967_12130	COG1438	arginine binding
ES967_12135	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ES967_12140	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ES967_12145	COG0142	geranyltranstransferase activity
ES967_12150	COG1722	exodeoxyribonuclease VII activity
ES967_12155	COG1570	exodeoxyribonuclease VII activity
ES967_12160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ES967_12165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ES967_12170	COG1302	Protein conserved in bacteria
ES967_12175	COG0439	Biotin carboxylase
ES967_12180	COG0511	ligase activity, forming carbon-carbon bonds
ES967_12220	COG3854	ATPases associated with a variety of cellular activities
ES967_12230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ES967_12235	COG0006	proline dipeptidase activity
ES967_12240	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ES967_12250	COG3872	metal-dependent enzyme
ES967_12260	COG1752	Esterase of the alpha-beta hydrolase superfamily
ES967_12265	COG1321	iron dependent repressor
ES967_12270	COG0095	Lipoate-protein ligase
ES967_12275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ES967_12280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ES967_12285	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ES967_12290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ES967_12295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ES967_12310	COG1396	sequence-specific DNA binding
ES967_12320	COG0681	Belongs to the peptidase S26 family
ES967_12345	COG4940	Competence protein ComGF
ES967_12355	COG4970	Tfp pilus assembly protein FimT
ES967_12360	COG4537	Required for transformation and DNA binding
ES967_12365	COG1459	type II secretion system
ES967_12370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ES967_12375	COG0517	IMP dehydrogenase activity
ES967_12380	COG0598	Magnesium transport protein CorA
ES967_12385	COG1253	flavin adenine dinucleotide binding
ES967_12390	COG1366	Belongs to the anti-sigma-factor antagonist family
ES967_12400	COG1393	Belongs to the ArsC family
ES967_12410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ES967_12420	COG0011	TIGRFAM Protein of
ES967_12430	COG2866	Carboxypeptidase
ES967_12435	COG1368	sulfuric ester hydrolase activity
ES967_12440	COG1940	carbohydrate kinase activity
ES967_12445	COG4483	Protein conserved in bacteria
ES967_12450	COG0705	Rhomboid family
ES967_12450	COG0457	Tetratricopeptide repeat
ES967_12460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ES967_12465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ES967_12470	COG0438	transferase activity, transferring glycosyl groups
ES967_12485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ES967_12490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ES967_12495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ES967_12500	COG0581	inorganic phosphate transmembrane transporter activity
ES967_12505	COG0573	inorganic phosphate transmembrane transporter activity
ES967_12510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ES967_12520	COG0477	Major facilitator Superfamily
ES967_12525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ES967_12530	COG2839	Protein conserved in bacteria
ES967_12535	COG5521	maltodextrose utilization protein MalA
ES967_12540	COG1388	LysM domain
ES967_12545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ES967_12550	COG4709	membrane
ES967_12555	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
ES967_12560	COG0735	belongs to the Fur family
ES967_12565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ES967_12575	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ES967_12580	COG0513	Belongs to the DEAD box helicase family
ES967_12590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ES967_12595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ES967_12600	COG2384	SAM-dependent methyltransferase
ES967_12605	COG2010	Cytochrome c
ES967_12615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ES967_12620	COG0358	DNA primase activity
ES967_12625	COG1671	Belongs to the UPF0178 family
ES967_12630	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ES967_12635	COG0517	IMP dehydrogenase activity
ES967_12640	COG0751	glycine-tRNA ligase activity
ES967_12645	COG0752	glycyl-tRNA synthetase alpha subunit
ES967_12650	COG1381	Involved in DNA repair and RecF pathway recombination
ES967_12660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ES967_12665	COG0295	cytidine deaminase activity
ES967_12670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ES967_12675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ES967_12680	COG1480	7TM receptor with intracellular HD hydrolase
ES967_12685	COG1702	phosphate starvation-inducible protein PhoH
ES967_12690	COG0561	phosphatase activity
ES967_12705	COG4864	UPF0365 protein
ES967_12710	COG1030	water channel activity
ES967_12715	COG1610	YqeY-like protein
ES967_12720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ES967_12725	COG1283	sodium-dependent phosphate transmembrane transporter activity
ES967_12730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ES967_12735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ES967_12740	COG2264	protein methyltransferase activity
ES967_12745	COG0484	heat shock protein binding
ES967_12750	COG0443	Heat shock 70 kDa protein
ES967_12755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ES967_12760	COG1420	regulation of RNA biosynthetic process
ES967_12765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ES967_12770	COG0481	GTPase activity
ES967_12780	COG0860	N-Acetylmuramoyl-L-alanine amidase
ES967_12785	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ES967_12790	COG0268	Binds directly to 16S ribosomal RNA
ES967_12795	COG1466	dna polymerase III delta subunit
ES967_12810	COG0658	competence protein
ES967_12810	COG2333	competence protein COMEC
ES967_12815	COG2131	deaminase
ES967_12820	COG1555	photosystem II stabilization
ES967_12820	COG1596	polysaccharide export
ES967_12825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ES967_12830	COG2226	methyltransferase
ES967_12835	COG0799	negative regulation of ribosome biogenesis
ES967_12840	COG1713	HD superfamily hydrolase involved in NAD metabolism
ES967_12845	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ES967_12850	COG1534	Rna-binding protein
ES967_12855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ES967_12860	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ES967_12865	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ES967_12875	COG2755	lipolytic protein G-D-S-L family
ES967_12880	COG3409	Peptidoglycan-binding domain 1 protein
ES967_12880	COG5632	N-Acetylmuramoyl-L-alanine amidase
ES967_12885	COG0398	Pfam SNARE associated Golgi protein
ES967_12890	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ES967_12900	COG3209	COG3209 Rhs family protein
ES967_12930	COG0604	alcohol dehydrogenase
ES967_12940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ES967_12945	COG0798	PFAM Bile acid sodium symporter
ES967_12950	COG0346	lactoylglutathione lyase activity
ES967_12955	COG0640	Transcriptional regulator
ES967_12960	COG0457	Tetratricopeptide repeat
ES967_12970	COG0656	L-ascorbic acid biosynthetic process
ES967_12985	COG5444	nuclease activity
ES967_12995	COG5632	N-Acetylmuramoyl-L-alanine amidase
ES967_12995	COG3409	Peptidoglycan-binding domain 1 protein
ES967_13055	COG3677	Transposase
ES967_13065	COG3209	COG3209 Rhs family protein
ES967_13105	COG0563	adenylate kinase activity
ES967_13120	COG2814	Major facilitator Superfamily
ES967_13125	COG1082	Xylose isomerase domain protein TIM barrel
ES967_13130	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_13135	COG1609	Transcriptional regulator
ES967_13145	COG0730	response to heat
ES967_13150	COG0425	Belongs to the sulfur carrier protein TusA family
ES967_13155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ES967_13155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ES967_13165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ES967_13165	COG0425	Belongs to the sulfur carrier protein TusA family
ES967_13170	COG2210	Belongs to the sulfur carrier protein TusA family
ES967_13175	COG1937	Protein conserved in bacteria
ES967_13190	COG0662	Cupin 2, conserved barrel domain protein
ES967_13210	COG0789	Transcriptional regulator
ES967_13210	COG4978	Transcriptional regulator
ES967_13215	COG2814	Major facilitator Superfamily
ES967_13220	COG0456	acetyltransferase
ES967_13225	COG1253	flavin adenine dinucleotide binding
ES967_13235	COG0697	spore germination
ES967_13240	COG0583	DNA-binding transcription factor activity
ES967_13245	COG2072	flavoprotein involved in K transport
ES967_13250	COG1230	cation diffusion facilitator family transporter
ES967_13255	COG1942	4-Oxalocrotonate Tautomerase
ES967_13260	COG0583	DNA-binding transcription factor activity
ES967_13270	COG1114	Component of the transport system for branched-chain amino acids
ES967_13275	COG1687	branched-chain amino acid
ES967_13280	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ES967_13285	COG1522	sequence-specific DNA binding
ES967_13295	COG2124	cytochrome p450
ES967_13305	COG1335	isochorismatase
ES967_13320	COG2318	DinB family
ES967_13330	COG2070	2-Nitropropane dioxygenase
ES967_13345	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ES967_13365	COG3443	Belongs to the bacterial solute-binding protein 9 family
ES967_13370	COG1595	DNA-templated transcription, initiation
ES967_13380	COG2851	Citrate transporter
ES967_13385	COG0583	DNA-binding transcription factor activity
ES967_13390	COG2828	Protein conserved in bacteria
ES967_13395	COG3409	Peptidoglycan-binding domain 1 protein
ES967_13400	COG5566	PFAM Mor transcription activator
ES967_13405	COG0596	Alpha beta hydrolase
ES967_13410	COG4991	sh3 domain protein
ES967_13415	COG4991	sh3 domain protein
ES967_13425	COG0346	lactoylglutathione lyase activity
ES967_13435	COG5577	PFAM Coat F domain
ES967_13440	COG1063	alcohol dehydrogenase
ES967_13450	COG5577	PFAM Coat F domain
ES967_13455	COG0789	Transcriptional regulator
ES967_13465	COG1064	alcohol dehydrogenase
ES967_13470	COG0693	protein deglycase activity
ES967_13475	COG1621	beta-fructofuranosidase activity
ES967_13480	COG3716	PTS system mannose fructose sorbose family IID component
ES967_13485	COG3715	PTS system
ES967_13490	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_13495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES967_13500	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ES967_13500	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ES967_13510	COG1113	amino acid transport
ES967_13515	COG1280	lysine exporter protein (LysE YggA)
ES967_13520	COG1378	Sugar-specific transcriptional regulator TrmB
ES967_13525	COG1595	DNA-templated transcription, initiation
ES967_13535	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ES967_13535	COG2755	lipolytic protein G-D-S-L family
ES967_13545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ES967_13545	COG2124	cytochrome p450
ES967_13550	COG1309	transcriptional regulator
ES967_13555	COG2226	methyltransferase
ES967_13570	COG2116	formate transmembrane transporter activity
ES967_13575	COG5609	conserved protein (DUF2294)
ES967_13580	COG3383	formate dehydrogenase (NAD+) activity
ES967_13585	COG2427	Protein of unknown function (DUF1641)
ES967_13595	COG0626	cystathionine gamma-synthase activity
ES967_13600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ES967_13605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ES967_13610	COG2226	methyltransferase
ES967_13625	COG0768	penicillin binding
ES967_13630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ES967_13635	COG0572	uridine kinase
ES967_13655	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ES967_13660	COG3906	Belongs to the UPF0473 family
ES967_13665	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ES967_13670	COG4472	Bacterial protein of unknown function (DUF965)
ES967_13675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ES967_13680	COG0628	permease
ES967_13685	COG1126	abc transporter atp-binding protein
ES967_13690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES967_13695	COG0765	amino acid transport
ES967_13700	COG0765	amino acid transport
ES967_13715	COG3881	PFAM PRC-barrel domain
ES967_13720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ES967_13725	COG0457	Tetratricopeptide repeat
ES967_13730	COG0482	sulfurtransferase activity
ES967_13735	COG1104	cysteine desulfurase activity
ES967_13740	COG1959	2 iron, 2 sulfur cluster binding
ES967_13745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ES967_13750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ES967_13760	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ES967_13765	COG0124	histidyl-tRNA synthetase
ES967_13775	COG3103	Sh3 type 3 domain protein
ES967_13775	COG0860	N-Acetylmuramoyl-L-alanine amidase
ES967_13775	COG4991	sh3 domain protein
ES967_13780	COG1490	D-aminoacyl-tRNA deacylase activity
ES967_13785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ES967_13790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ES967_13795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ES967_13795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ES967_13800	COG5416	Lipopolysaccharide assembly protein A domain
ES967_13805	COG0490	domain, Protein
ES967_13810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ES967_13810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ES967_13820	COG2244	polysaccharide biosynthetic process
ES967_13825	COG2323	membrane
ES967_13835	COG1862	Preprotein translocase
ES967_13845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ES967_13855	COG2255	four-way junction helicase activity
ES967_13860	COG0632	four-way junction helicase activity
ES967_13870	COG2814	Major facilitator Superfamily
ES967_13875	COG0673	inositol 2-dehydrogenase activity
ES967_13880	COG2112	serine threonine protein kinase
ES967_13900	COG1115	amino acid carrier protein
ES967_13905	COG0217	transcriptional regulatory protein
ES967_13915	COG1388	LysM domain
ES967_13920	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ES967_13925	COG0157	Belongs to the NadC ModD family
ES967_13930	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ES967_13935	COG1104	cysteine desulfurase activity
ES967_13940	COG1827	regulation of RNA biosynthetic process
ES967_13945	COG0077	Prephenate dehydratase
ES967_13950	COG4492	Belongs to the UPF0735 family
ES967_13955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ES967_13960	COG3290	protein histidine kinase activity
ES967_13970	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ES967_13975	COG2868	ribosomal protein
ES967_13980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ES967_13985	COG1994	Peptidase M50
ES967_13990	COG0739	heme binding
ES967_13995	COG2894	cell division
ES967_14000	COG0850	regulation of cytokinetic process
ES967_14005	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ES967_14010	COG1792	Involved in formation and maintenance of cell shape
ES967_14015	COG1077	Cell shape determining protein MreB Mrl
ES967_14020	COG2003	Belongs to the UPF0758 family
ES967_14025	COG0424	maF-like protein
ES967_14035	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ES967_14040	COG0285	dihydrofolate synthase activity
ES967_14045	COG0525	valine-tRNA ligase activity
ES967_14055	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ES967_14060	COG1388	LysM domain
ES967_14065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ES967_14070	COG0113	porphobilinogen synthase activity
ES967_14075	COG1587	Uroporphyrinogen-III synthase
ES967_14080	COG0181	hydroxymethylbilane synthase activity
ES967_14085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ES967_14090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ES967_14100	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ES967_14105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ES967_14110	COG0470	DNA polymerase III
ES967_14110	COG1067	ATP-dependent peptidase activity
ES967_14115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ES967_14120	COG0544	peptidyl-prolyl cis-trans isomerase activity
ES967_14125	COG0457	Tetratricopeptide repeat
ES967_14125	COG1477	protein flavinylation
ES967_14130	COG0066	3-isopropylmalate dehydratase activity
ES967_14135	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ES967_14140	COG0473	3-isopropylmalate dehydrogenase activity
ES967_14145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ES967_14150	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ES967_14155	COG0440	acetolactate synthase activity
ES967_14160	COG0028	Belongs to the TPP enzyme family
ES967_14170	COG0454	-acetyltransferase
ES967_14175	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
ES967_14185	COG0622	Phosphoesterase
ES967_14190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ES967_14195	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ES967_14200	COG5401	PFAM Sporulation and spore germination
ES967_14205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ES967_14210	COG1846	Transcriptional regulator
ES967_14215	COG2197	response regulator
ES967_14220	COG0824	Thioesterase
ES967_14225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ES967_14230	COG1053	succinate dehydrogenase
ES967_14235	COG2009	succinate dehydrogenase
ES967_14240	COG1719	4-vinyl reductase, 4VR
ES967_14245	COG0527	aspartate kinase activity
ES967_14255	COG0322	excinuclease ABC activity
ES967_14260	COG3118	belongs to the thioredoxin family
ES967_14270	COG3534	alpha-L-arabinofuranosidase
ES967_14275	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ES967_14280	COG2086	electron transfer activity
ES967_14285	COG1024	Enoyl-CoA hydratase
ES967_14290	COG1309	transcriptional regulator
ES967_14295	COG0318	PFAM AMP-dependent synthetase and ligase
ES967_14300	COG3766	membrane
ES967_14305	COG1193	negative regulation of DNA recombination
ES967_14310	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ES967_14310	COG1796	DNA polymerase
ES967_14315	COG1286	toxin biosynthetic process
ES967_14320	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ES967_14325	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ES967_14330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ES967_14330	COG0072	phenylalanine-tRNA ligase activity
ES967_14335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ES967_14345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ES967_14355	COG3835	regulator
ES967_14360	COG0277	FAD linked oxidase domain protein
ES967_14365	COG0247	lactate metabolic process
ES967_14370	COG0346	lactoylglutathione lyase activity
ES967_14380	COG1966	Carbon starvation protein
ES967_14385	COG3534	alpha-L-arabinofuranosidase
ES967_14390	COG0395	ABC-type sugar transport system, permease component
ES967_14395	COG1175	transmembrane transport
ES967_14400	COG1653	transport
ES967_14405	COG0371	Dehydrogenase
ES967_14410	COG0647	UMP catabolic process
ES967_14415	COG0235	Class ii aldolase
ES967_14420	COG1069	ribulokinase activity
ES967_14425	COG2160	L-arabinose isomerase activity
ES967_14430	COG3507	Belongs to the glycosyl hydrolase 43 family
ES967_14435	COG1363	Peptidase, m42
ES967_14445	COG3326	Membrane
ES967_14450	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ES967_14455	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ES967_14460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ES967_14470	COG1346	cytolysis
ES967_14475	COG1380	Effector of murein hydrolase LrgA
ES967_14480	COG3279	Response regulator of the LytR AlgR family
ES967_14485	COG3275	phosphorelay sensor kinase activity
ES967_14495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ES967_14505	COG0398	Pfam SNARE associated Golgi protein
ES967_14510	COG1484	DNA-dependent DNA replication
ES967_14515	COG3611	Membrane attachment protein
ES967_14520	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ES967_14525	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ES967_14530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ES967_14535	COG1733	regulation of RNA biosynthetic process
ES967_14540	COG2814	Major facilitator Superfamily
ES967_14545	COG0656	L-ascorbic acid biosynthetic process
ES967_14550	COG0237	dephospho-CoA kinase activity
ES967_14555	COG1971	Probably functions as a manganese efflux pump
ES967_14560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ES967_14565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ES967_14565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ES967_14570	COG5002	protein histidine kinase activity
ES967_14575	COG0745	RESPONSE REGULATOR receiver
ES967_14580	COG0039	L-malate dehydrogenase activity
ES967_14585	COG0538	isocitrate dehydrogenase activity
ES967_14590	COG0372	Belongs to the citrate synthase family
ES967_14595	COG2707	UPF0756 membrane protein
ES967_14600	COG0628	permease
ES967_14605	COG3030	protein affecting phage T7 exclusion by the F plasmid
ES967_14610	COG0469	pyruvate kinase activity
ES967_14615	COG0205	6-phosphofructokinase activity
ES967_14620	COG0825	malonyl-CoA metabolic process
ES967_14625	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ES967_14630	COG0281	malic enzyme
ES967_14635	COG0587	DNA-directed DNA polymerase activity
ES967_14655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ES967_14665	COG4109	DRTGG domain
ES967_14670	COG0730	response to heat
ES967_14675	COG1473	amidohydrolase
ES967_14680	COG0196	riboflavin kinase activity
ES967_14685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ES967_14690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ES967_14695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ES967_14700	COG1126	abc transporter atp-binding protein
ES967_14705	COG0765	amino acid transport
ES967_14710	COG0765	amino acid transport
ES967_14715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES967_14720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES967_14725	COG0454	-acetyltransferase
ES967_14730	COG0583	DNA-binding transcription factor activity
ES967_14735	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ES967_14740	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_14750	COG0165	Argininosuccinate lyase
ES967_14755	COG0137	argininosuccinate synthase activity
ES967_14760	COG0521	Mo-molybdopterin cofactor biosynthetic process
ES967_14765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ES967_14775	COG0827	DNA restriction-modification system
ES967_14780	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ES967_14785	COG3874	Sporulation protein YtfJ
ES967_14795	COG1714	RDD family
ES967_14800	COG0616	signal peptide processing
ES967_14805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ES967_14810	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ES967_14815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ES967_14825	COG0301	tRNA thio-modification
ES967_14830	COG1104	cysteine desulfurase activity
ES967_14835	COG1114	Component of the transport system for branched-chain amino acids
ES967_14840	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ES967_14845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ES967_14850	COG1309	transcriptional regulator
ES967_14855	COG1956	GAF domain-containing protein
ES967_14860	COG2199	diguanylate cyclase activity
ES967_14860	COG2203	Gaf domain
ES967_14870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ES967_14875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ES967_14880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ES967_14885	COG0454	-acetyltransferase
ES967_14890	COG0517	IMP dehydrogenase activity
ES967_14895	COG0123	including yeast histone deacetylase and acetoin utilization protein
ES967_14900	COG1360	Flagellar Motor Protein
ES967_14905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ES967_14910	COG1609	Transcriptional regulator
ES967_14915	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ES967_14915	COG1605	Chorismate mutase
ES967_14920	COG3118	belongs to the thioredoxin family
ES967_14925	COG4980	gas vesicle protein
ES967_14930	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ES967_14935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ES967_14940	COG1674	ftsk spoiiie
ES967_14945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ES967_14950	COG4848	Belongs to the UPF0354 family
ES967_14955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES967_14970	COG1363	Peptidase, m42
ES967_14975	COG5584	Small secreted protein
ES967_14980	COG0281	malic enzyme
ES967_14985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ES967_14990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ES967_15000	COG0510	thiamine kinase activity
ES967_15005	COG1523	belongs to the glycosyl hydrolase 13 family
ES967_15010	COG1597	lipid kinase activity
ES967_15020	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ES967_15025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ES967_15030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ES967_15035	COG2252	PERMEase
ES967_15040	COG4473	ABC transporter
ES967_15045	COG1131	(ABC) transporter
ES967_15050	COG1349	DNA-binding transcription factor activity
ES967_15055	COG1187	pseudouridine synthase activity
ES967_15060	COG2244	polysaccharide biosynthetic process
ES967_15065	COG2081	HI0933 family
ES967_15070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ES967_15080	COG5578	integral membrane protein
ES967_15085	COG0673	inositol 2-dehydrogenase activity
ES967_15090	COG1653	transport
ES967_15095	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ES967_15100	COG4209	transmembrane transport
ES967_15105	COG2207	Transcriptional regulator
ES967_15110	COG1653	transport
ES967_15115	COG0395	ABC-type sugar transport system, permease component
ES967_15120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ES967_15125	COG2124	cytochrome p450
ES967_15130	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ES967_15140	COG0156	8-amino-7-oxononanoate synthase activity
ES967_15145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ES967_15155	COG1073	alpha beta
ES967_15180	COG1486	melibiose metabolic process
ES967_15185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ES967_15190	COG0495	leucyl-tRNA aminoacylation
ES967_15200	COG1366	Belongs to the anti-sigma-factor antagonist family
ES967_15200	COG2202	Pas domain
ES967_15210	COG2814	Major facilitator Superfamily
ES967_15215	COG2433	Pfam Transposase IS66
ES967_15220	COG0577	efflux transmembrane transporter activity
ES967_15225	COG1136	(ABC) transporter
ES967_15230	COG2205	protein histidine kinase activity
ES967_15235	COG0745	RESPONSE REGULATOR receiver
ES967_15240	COG0577	efflux transmembrane transporter activity
ES967_15245	COG1136	(ABC) transporter
ES967_15260	COG1131	(ABC) transporter
ES967_15265	COG1725	Transcriptional regulator
ES967_15280	COG1242	4 iron, 4 sulfur cluster binding
ES967_15285	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ES967_15295	COG2267	carboxylic ester hydrolase activity
ES967_15300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ES967_15305	COG1113	amino acid transport
ES967_15310	COG0367	asparagine synthase
ES967_15315	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ES967_15320	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ES967_15330	COG1506	peptidase
ES967_15335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ES967_15340	COG1116	anion transmembrane transporter activity
ES967_15345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ES967_15350	COG0494	nUDIX hydrolase
ES967_15355	COG4824	toxin secretion phage lysis holin
ES967_15360	COG0783	Belongs to the Dps family
ES967_15375	COG1854	S-ribosylhomocysteine lyase activity
ES967_15380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ES967_15385	COG0288	reversible hydration of carbon dioxide
ES967_15390	COG0254	rRNA binding
ES967_15395	COG1271	oxidase subunit
ES967_15400	COG1294	oxidase, subunit
ES967_15410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ES967_15415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ES967_15415	COG1321	iron dependent repressor
ES967_15420	COG1121	(ABC) transporter
ES967_15425	COG0803	Belongs to the bacterial solute-binding protein 9 family
ES967_15435	COG4948	Mandelate Racemase Muconate Lactonizing
ES967_15440	COG0318	PFAM AMP-dependent synthetase and ligase
ES967_15445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ES967_15450	COG0596	Alpha beta hydrolase
ES967_15455	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ES967_15460	COG1169	isochorismate synthase
ES967_15470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ES967_15475	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ES967_15480	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ES967_15485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ES967_15490	COG0438	transferase activity, transferring glycosyl groups
ES967_15500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ES967_15505	COG0438	transferase activity, transferring glycosyl groups
ES967_15510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ES967_15515	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ES967_15520	COG0058	SHG alpha-glucan phosphorylase activity
ES967_15525	COG0297	glycogen (starch) synthase activity
ES967_15530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ES967_15535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ES967_15540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ES967_15665	COG3859	Proton-coupled thiamine transporter YuaJ
ES967_15670	COG1247	-acetyltransferase
ES967_15675	COG2268	Band 7 protein
ES967_15680	COG1585	Membrane protein implicated in regulation of membrane protease activity
ES967_15685	COG2318	DinB family
ES967_15695	COG1454	alcohol dehydrogenase
ES967_15705	COG1510	regulation of RNA biosynthetic process
ES967_15715	COG0569	domain protein
ES967_15720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ES967_15725	COG4682	membrane
ES967_15730	COG1705	Flagellar rod assembly protein muramidase FlgJ
ES967_15735	COG0477	Major facilitator Superfamily
ES967_15740	COG5553	Cysteine dioxygenase type I
ES967_15750	COG1968	undecaprenyl-diphosphatase activity
ES967_15755	COG0628	permease
ES967_15760	COG0673	inositol 2-dehydrogenase activity
ES967_15765	COG4806	L-rhamnose isomerase
ES967_15770	COG3254	rhamnose metabolic process
ES967_15775	COG1070	Carbohydrate kinase
ES967_15780	COG1349	DNA-binding transcription factor activity
ES967_15785	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_15785	COG3347	Dehydrogenase
ES967_15795	COG0840	transmembrane signaling receptor activity
ES967_15800	COG0840	transmembrane signaling receptor activity
ES967_15805	COG0840	transmembrane signaling receptor activity
ES967_15810	COG0840	transmembrane signaling receptor activity
ES967_15825	COG0432	Pfam Uncharacterised protein family UPF0047
ES967_15835	COG0366	Alpha amylase catalytic
ES967_15840	COG1253	flavin adenine dinucleotide binding
ES967_15845	COG2738	Putative neutral zinc metallopeptidase
ES967_15860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ES967_15875	COG0166	Belongs to the GPI family
ES967_15880	COG1979	alcohol dehydrogenase
ES967_15885	COG1979	alcohol dehydrogenase
ES967_15890	COG2155	Conserved Protein
ES967_15895	COG1098	S1 RNA binding domain
ES967_15900	COG0436	Aminotransferase
ES967_15905	COG1522	sequence-specific DNA binding
ES967_15910	COG2267	carboxylic ester hydrolase activity
ES967_15920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ES967_15925	COG2205	protein histidine kinase activity
ES967_15935	COG5018	Exonuclease
ES967_15945	COG2814	Major facilitator Superfamily
ES967_15950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ES967_15955	COG3011	Protein conserved in bacteria
ES967_15965	COG3290	protein histidine kinase activity
ES967_15970	COG4565	transcriptional regulatory protein
ES967_15995	COG3493	citrate carrier protein
ES967_16005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ES967_16005	COG2111	Na H antiporter
ES967_16010	COG2111	Na H antiporter
ES967_16015	COG1006	Multisubunit Na H antiporter MnhC subunit
ES967_16020	COG0651	ATP synthesis coupled electron transport
ES967_16025	COG1863	multisubunit Na H antiporter MnhE subunit
ES967_16030	COG2212	antiporter activity
ES967_16035	COG1320	monovalent cation:proton antiporter activity
ES967_16040	COG2050	protein possibly involved in aromatic compounds catabolism
ES967_16045	COG2197	response regulator
ES967_16050	COG4585	Histidine kinase
ES967_16060	COG0142	geranyltranstransferase activity
ES967_16080	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ES967_16085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ES967_16090	COG1335	isochorismatase
ES967_16095	COG5506	Protein of unknown function (DUF1694)
ES967_16110	COG0628	permease
ES967_16125	COG1418	mRNA catabolic process
ES967_16130	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_16140	COG1511	domain protein
ES967_16145	COG0433	COG0433 Predicted ATPase
ES967_16145	COG1674	ftsk spoiiie
ES967_16150	COG4499	WXG100 protein secretion system (Wss), protein YukC
ES967_16155	COG5417	Belongs to the EsaB family
ES967_16160	COG4842	Belongs to the WXG100 family
ES967_16170	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ES967_16170	COG2508	Transcriptional regulator
ES967_16175	COG0686	Belongs to the AlaDH PNT family
ES967_16180	COG5634	Uncharacterized conserved protein (DUF2278)
ES967_16185	COG3251	PFAM MbtH domain protein
ES967_16190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_16195	COG3433	isochorismatase activity
ES967_16195	COG1535	isochorismatase
ES967_16200	COG1021	2,3-dihydroxybenzoate-AMP ligase
ES967_16205	COG1169	isochorismate synthase
ES967_16210	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_16215	COG2819	hydrolase of the alpha beta superfamily
ES967_16220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ES967_16225	COG1268	BioY protein
ES967_16230	COG2056	Na+-H+ antiporter family
ES967_16235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ES967_16240	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ES967_16245	COG3584	3D domain protein
ES967_16260	COG1252	NADH dehydrogenase
ES967_16265	COG0492	ferredoxin-NADP+ reductase activity
ES967_16275	COG0516	GMP reductase activity
ES967_16280	COG2808	Putative FMN-binding domain
ES967_16285	COG0456	acetyltransferase
ES967_16290	COG0316	Belongs to the HesB IscA family
ES967_16295	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ES967_16300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ES967_16305	COG4844	belongs to the
ES967_16310	COG1252	NADH dehydrogenase
ES967_16315	COG4837	Protein of unknown function (DUF1462)
ES967_16320	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ES967_16325	COG0823	Involved in the tonB-independent uptake of proteins
ES967_16325	COG1506	peptidase
ES967_16325	COG4946	Tricorn protease homolog
ES967_16330	COG0083	homoserine kinase activity
ES967_16335	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ES967_16340	COG0460	homoserine dehydrogenase
ES967_16345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ES967_16350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ES967_16355	COG0647	UMP catabolic process
ES967_16360	COG2445	Protein of unknown function DUF86
ES967_16365	COG4470	Protein conserved in bacteria
ES967_16375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ES967_16380	COG0739	heme binding
ES967_16390	COG3377	Domain of unknown function (DUF1805)
ES967_16395	COG0737	Belongs to the 5'-nucleotidase family
ES967_16400	COG0730	response to heat
ES967_16405	COG1801	Protein of unknown function DUF72
ES967_16415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ES967_16420	COG2508	Transcriptional regulator
ES967_16425	COG2233	PERMEase
ES967_16430	COG2233	PERMEase
ES967_16435	COG3648	Uricase
ES967_16435	COG3195	allantoin biosynthetic process
ES967_16440	COG2351	hydroxyisourate hydrolase activity
ES967_16450	COG2080	2 iron, 2 sulfur cluster binding
ES967_16455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ES967_16460	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ES967_16465	COG2068	MobA-Related Protein
ES967_16470	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ES967_16475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ES967_16480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ES967_16490	COG2356	endonuclease I
ES967_16495	COG3842	ATPase activity
ES967_16500	COG2188	Transcriptional regulator
ES967_16505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ES967_16510	COG0395	ABC-type sugar transport system, permease component
ES967_16515	COG1175	transmembrane transport
ES967_16520	COG1653	transport
ES967_16525	COG2222	sugar isomerase
ES967_16530	COG0322	excinuclease ABC activity
ES967_16535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ES967_16550	COG0346	lactoylglutathione lyase activity
ES967_16555	COG0640	Transcriptional regulator
ES967_16560	COG0719	Fe-S assembly protein
ES967_16565	COG0822	iron-sulfur transferase activity
ES967_16570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ES967_16575	COG0719	Fe-S assembly protein
ES967_16580	COG0396	ATPase activity
ES967_16595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ES967_16600	COG1464	Belongs to the NlpA lipoprotein family
ES967_16605	COG2011	ABC-type metal ion transport system permease component
ES967_16610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ES967_16620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES967_16625	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ES967_16635	COG0509	glycine decarboxylation via glycine cleavage system
ES967_16640	COG1393	Belongs to the ArsC family
ES967_16645	COG1960	acyl-CoA dehydrogenase activity
ES967_16650	COG0183	Belongs to the thiolase family
ES967_16655	COG1024	Enoyl-CoA hydratase
ES967_16655	COG1250	3-hydroxyacyl-CoA dehydrogenase
ES967_16665	COG0506	proline dehydrogenase activity
ES967_16675	COG5577	PFAM Coat F domain
ES967_16680	COG1846	Transcriptional regulator
ES967_16685	COG0477	Major facilitator Superfamily
ES967_16690	COG1942	4-Oxalocrotonate Tautomerase
ES967_16700	COG0583	DNA-binding transcription factor activity
ES967_16710	COG1120	ATPase activity
ES967_16725	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_16730	COG0783	Belongs to the Dps family
ES967_16735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ES967_16740	COG0745	RESPONSE REGULATOR receiver
ES967_16745	COG2205	protein histidine kinase activity
ES967_16745	COG2770	Histidine kinase
ES967_16755	COG1309	transcriptional regulator
ES967_16760	COG0114	fumarate hydratase activity
ES967_16770	COG0697	spore germination
ES967_16775	COG0814	amino acid
ES967_16785	COG2197	response regulator
ES967_16790	COG4585	Histidine kinase
ES967_16795	COG4758	membrane
ES967_16800	COG3595	metallopeptidase activity
ES967_16805	COG1842	Phage shock protein A
ES967_16810	COG4758	membrane
ES967_16815	COG2814	Major facilitator Superfamily
ES967_16820	COG2096	Adenosyltransferase
ES967_16825	COG1120	ATPase activity
ES967_16830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES967_16835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ES967_16840	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_16845	COG3386	PFAM SMP-30 Gluconolaconase
ES967_16850	COG2205	protein histidine kinase activity
ES967_16855	COG0745	RESPONSE REGULATOR receiver
ES967_16865	COG1191	sigma factor activity
ES967_16875	COG2140	Oxalate decarboxylase
ES967_16885	COG0577	efflux transmembrane transporter activity
ES967_16890	COG1136	(ABC) transporter
ES967_16895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ES967_16900	COG1120	ATPase activity
ES967_16905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES967_16910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES967_16915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ES967_16920	COG0531	amino acid
ES967_16935	COG1988	membrane-bound metal-dependent
ES967_16940	COG1368	sulfuric ester hydrolase activity
ES967_16945	COG1910	domain protein
ES967_16950	COG0725	ABC transporter, periplasmic molybdate-binding protein
ES967_16955	COG4149	molybdate abc transporter
ES967_16960	COG0656	L-ascorbic acid biosynthetic process
ES967_16970	COG0025	NhaP-type Na H and K H
ES967_16975	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ES967_16980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ES967_16985	COG3973	AAA domain
ES967_16990	COG2860	membrane
ES967_16995	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ES967_17000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ES967_17005	COG2217	Heavy metal translocating P-type atpase
ES967_17010	COG2217	Heavy metal translocating P-type atpase
ES967_17015	COG2608	mercury ion transmembrane transporter activity
ES967_17020	COG1937	Protein conserved in bacteria
ES967_17025	COG0673	inositol 2-dehydrogenase activity
ES967_17030	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ES967_17045	COG2076	Multidrug Resistance protein
ES967_17050	COG1309	transcriptional regulator
ES967_17055	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_17065	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ES967_17070	COG0557	exoribonuclease II activity
ES967_17075	COG1647	Serine aminopeptidase, S33
ES967_17080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ES967_17085	COG0596	Alpha beta hydrolase
ES967_17090	COG1476	TRANSCRIPTIONal
ES967_17095	COG1396	sequence-specific DNA binding
ES967_17100	COG1396	sequence-specific DNA binding
ES967_17105	COG1733	regulation of RNA biosynthetic process
ES967_17110	COG0840	transmembrane signaling receptor activity
ES967_17115	COG1174	glycine betaine transport
ES967_17120	COG1732	Glycine betaine
ES967_17125	COG1174	glycine betaine transport
ES967_17130	COG0517	IMP dehydrogenase activity
ES967_17130	COG1125	glycine betaine transport
ES967_17135	COG1510	regulation of RNA biosynthetic process
ES967_17155	COG5658	integral membrane protein
ES967_17160	COG0640	Transcriptional regulator
ES967_17165	COG1174	glycine betaine transport
ES967_17170	COG1732	Glycine betaine
ES967_17175	COG1174	glycine betaine transport
ES967_17180	COG1125	glycine betaine transport
ES967_17180	COG0517	IMP dehydrogenase activity
ES967_17185	COG1510	regulation of RNA biosynthetic process
ES967_17190	COG2095	MarC family integral membrane protein
ES967_17200	COG3064	Membrane
ES967_17205	COG4640	response to antibiotic
ES967_17210	COG0456	acetyltransferase
ES967_17215	COG0148	phosphopyruvate hydratase activity
ES967_17220	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ES967_17225	COG0149	triose-phosphate isomerase activity
ES967_17230	COG0126	phosphoglycerate kinase activity
ES967_17235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ES967_17240	COG2390	Transcriptional regulator
ES967_17245	COG2814	Major facilitator Superfamily
ES967_17250	COG1609	Transcriptional regulator
ES967_17255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ES967_17265	COG0583	DNA-binding transcription factor activity
ES967_17270	COG0697	spore germination
ES967_17275	COG1113	amino acid transport
ES967_17280	COG3858	chitin binding
ES967_17285	COG1556	Lactate utilization protein
ES967_17290	COG1139	Iron-sulfur cluster binding protein
ES967_17295	COG0247	lactate metabolic process
ES967_17300	COG2197	response regulator
ES967_17305	COG4585	Histidine kinase
ES967_17310	COG0842	Transport permease protein
ES967_17315	COG1131	(ABC) transporter
ES967_17320	COG0596	Alpha beta hydrolase
ES967_17325	COG2208	phosphoserine phosphatase activity
ES967_17330	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ES967_17335	COG1874	Beta-galactosidase
ES967_17340	COG3833	ABC-type maltose transport systems, permease component
ES967_17345	COG1175	transmembrane transport
ES967_17350	COG2182	Extracellular solute-binding protein
ES967_17355	COG1609	Transcriptional regulator
ES967_17360	COG2186	Transcriptional regulator
ES967_17365	COG1620	l-lactate permease
ES967_17370	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ES967_17380	COG5039	Polysaccharide pyruvyl transferase
ES967_17385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ES967_17390	COG0110	maltose O-acetyltransferase activity
ES967_17395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ES967_17400	COG2244	polysaccharide biosynthetic process
ES967_17405	COG1216	Glycosyl transferase, family 2
ES967_17410	COG5039	Polysaccharide pyruvyl transferase
ES967_17415	COG1216	Glycosyl transferase, family 2
ES967_17425	COG0438	transferase activity, transferring glycosyl groups
ES967_17430	COG1215	transferase activity, transferring glycosyl groups
ES967_17435	COG0438	transferase activity, transferring glycosyl groups
ES967_17440	COG1086	Polysaccharide biosynthesis protein
ES967_17445	COG0489	protein tyrosine kinase activity
ES967_17450	COG3944	biosynthesis protein
ES967_17455	COG1396	sequence-specific DNA binding
ES967_17460	COG2272	Belongs to the type-B carboxylesterase lipase family
ES967_17470	COG3479	Phenolic acid decarboxylase
ES967_17480	COG1794	racemase activity, acting on amino acids and derivatives
ES967_17485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ES967_17490	COG1621	beta-fructofuranosidase activity
ES967_17495	COG1621	beta-fructofuranosidase activity
ES967_17500	COG0531	amino acid
ES967_17505	COG1309	transcriptional regulator
ES967_17510	COG2076	Multidrug Resistance protein
ES967_17515	COG2076	Multidrug Resistance protein
ES967_17525	COG0277	FAD linked oxidase domain protein
ES967_17530	COG3621	Patatin-like phospholipase
ES967_17540	COG0740	serine-type endopeptidase activity
ES967_17545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ES967_17550	COG0366	Alpha amylase catalytic
ES967_17555	COG1554	hydrolase, family 65, central catalytic
ES967_17560	COG5521	maltodextrose utilization protein MalA
ES967_17565	COG3833	ABC-type maltose transport systems, permease component
ES967_17570	COG1175	transmembrane transport
ES967_17575	COG2182	Extracellular solute-binding protein
ES967_17580	COG0366	Alpha amylase catalytic
ES967_17585	COG1609	Transcriptional regulator
ES967_17590	COG1611	Belongs to the LOG family
ES967_17595	COG1694	Mazg nucleotide pyrophosphohydrolase
ES967_17600	COG0659	secondary active sulfate transmembrane transporter activity
ES967_17605	COG0288	reversible hydration of carbon dioxide
ES967_17615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ES967_17620	COG0577	efflux transmembrane transporter activity
ES967_17625	COG1136	(ABC) transporter
ES967_17630	COG5002	protein histidine kinase activity
ES967_17635	COG0745	RESPONSE REGULATOR receiver
ES967_17645	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ES967_17650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES967_17655	COG1481	regulation of sporulation
ES967_17660	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ES967_17665	COG1660	Displays ATPase and GTPase activities
ES967_17670	COG1051	belongs to the nudix hydrolase family
ES967_17675	COG0492	ferredoxin-NADP+ reductase activity
ES967_17680	COG0791	NLP P60 protein
ES967_17680	COG3883	PFAM NLP P60 protein
ES967_17685	COG0457	Tetratricopeptide repeat
ES967_17690	COG1132	(ABC) transporter
ES967_17710	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ES967_17710	COG0140	phosphoribosyl-ATP diphosphatase activity
ES967_17715	COG0107	imidazoleglycerol-phosphate synthase activity
ES967_17720	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ES967_17725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ES967_17730	COG0131	Imidazoleglycerol-phosphate dehydratase
ES967_17735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ES967_17740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ES967_17745	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ES967_17750	COG4990	cell redox homeostasis
ES967_17755	COG5297	Belongs to the glycosyl hydrolase family 6
ES967_17760	COG0110	maltose O-acetyltransferase activity
ES967_17765	COG0546	phosphoglycolate phosphatase activity
ES967_17770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ES967_17775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ES967_17780	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ES967_17785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ES967_17790	COG0363	glucosamine-6-phosphate deaminase activity
ES967_17800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ES967_17805	COG1846	Transcriptional regulator
ES967_17810	COG2124	cytochrome p450
ES967_17825	COG2814	Major facilitator Superfamily
ES967_17830	COG1950	PFAM Membrane protein of
ES967_17835	COG1983	PspC domain protein
ES967_17840	COG3595	metallopeptidase activity
ES967_17860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ES967_17865	COG0556	nucleotide-excision repair
ES967_17870	COG4897	Protein conserved in bacteria
ES967_17875	COG0574	Belongs to the PEP-utilizing enzyme family
ES967_17875	COG3848	Pyruvate phosphate dikinase
ES967_17880	COG1309	transcriptional regulator
ES967_17885	COG2814	Major facilitator Superfamily
ES967_17890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ES967_17900	COG3409	Peptidoglycan-binding domain 1 protein
ES967_17900	COG0793	Belongs to the peptidase S41A family
ES967_17905	COG2177	Part of the ABC transporter FtsEX involved in
ES967_17910	COG2884	Cell division ATP-binding protein ftsE
ES967_17915	COG2010	Cytochrome c
ES967_17920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ES967_17930	COG0653	protein targeting
ES967_17935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ES967_17950	COG1516	flagellar protein fliS
ES967_17955	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ES967_17960	COG1334	flagellar protein FlaG
ES967_17965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ES967_17970	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ES967_17975	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ES967_17985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ES967_17990	COG4786	Flagellar basal body rod
ES967_17990	COG1256	bacterial-type flagellum assembly
ES967_17995	COG3418	PFAM FlgN family protein
ES967_18000	COG2747	anti-sigma28 factor FlgM
ES967_18010	COG1040	competence protein
ES967_18020	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ES967_18025	COG1307	EDD domain protein, DegV family
ES967_18030	COG2197	response regulator
ES967_18035	COG4585	Histidine kinase
ES967_18040	COG1739	Uncharacterized protein family UPF0029
ES967_18045	COG1316	TRANSCRIPTIONal
ES967_18050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ES967_18055	COG0438	transferase activity, transferring glycosyl groups
ES967_18060	COG1215	transferase activity, transferring glycosyl groups
ES967_18065	COG3206	protein involved in exopolysaccharide biosynthesis
ES967_18070	COG3307	-O-antigen
ES967_18075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ES967_18080	COG0297	glycogen (starch) synthase activity
ES967_18080	COG0438	transferase activity, transferring glycosyl groups
ES967_18085	COG2244	polysaccharide biosynthetic process
ES967_18095	COG0860	N-Acetylmuramoyl-L-alanine amidase
ES967_18095	COG2247	cell wall binding repeat
ES967_18100	COG2385	sporulation resulting in formation of a cellular spore
ES967_18100	COG2247	cell wall binding repeat
ES967_18110	COG1316	TRANSCRIPTIONal
ES967_18115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ES967_18120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ES967_18130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ES967_18130	COG1215	transferase activity, transferring glycosyl groups
ES967_18135	COG0463	Glycosyl transferase, family 2
ES967_18145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ES967_18155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ES967_18160	COG1134	teichoic acid transport
ES967_18165	COG1682	transport, permease protein
ES967_18170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ES967_18175	COG0438	transferase activity, transferring glycosyl groups
ES967_18180	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ES967_18185	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ES967_18190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ES967_18200	COG4193	domain, Protein
ES967_18205	COG1482	cell wall glycoprotein biosynthetic process
ES967_18210	COG0697	spore germination
ES967_18215	COG0814	amino acid
ES967_18225	COG2814	Major facilitator Superfamily
ES967_18230	COG1316	TRANSCRIPTIONal
ES967_18235	COG0561	phosphatase activity
ES967_18240	COG0791	NLP P60 protein
ES967_18250	COG2843	Capsule synthesis protein
ES967_18260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ES967_18270	COG1609	Transcriptional regulator
ES967_18275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ES967_18280	COG1869	D-ribose catabolic process
ES967_18285	COG1129	ABC transporter
ES967_18290	COG1172	Belongs to the binding-protein-dependent transport system permease family
ES967_18295	COG1879	ABC-type sugar transport system periplasmic component
ES967_18300	COG3103	Sh3 type 3 domain protein
ES967_18310	COG2249	NAD(P)H dehydrogenase (quinone) activity
ES967_18315	COG3527	Alpha-acetolactate decarboxylase
ES967_18320	COG0028	Belongs to the TPP enzyme family
ES967_18325	COG0583	DNA-binding transcription factor activity
ES967_18330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ES967_18345	COG5337	Spore coat protein CotH
ES967_18355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ES967_18365	COG0405	Gamma-glutamyltransferase
ES967_18370	COG1522	sequence-specific DNA binding
ES967_18375	COG2059	Chromate
ES967_18380	COG2059	Chromate
ES967_18390	COG0655	NAD(P)H dehydrogenase (quinone) activity
ES967_18395	COG0583	DNA-binding transcription factor activity
ES967_18410	COG5444	nuclease activity
ES967_18430	COG3878	Protein conserved in bacteria
ES967_18435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ES967_18440	COG4464	protein tyrosine phosphatase activity
ES967_18445	COG0489	protein tyrosine kinase activity
ES967_18450	COG3944	biosynthesis protein
ES967_18460	COG4715	Zinc finger, swim domain protein
ES967_18465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ES967_18470	COG0561	phosphatase activity
ES967_18475	COG1349	DNA-binding transcription factor activity
ES967_18480	COG0629	single-stranded DNA binding
ES967_18495	COG3764	Sortase (surface protein transpeptidase)
ES967_18505	COG2972	Histidine kinase
ES967_18505	COG0745	RESPONSE REGULATOR receiver
ES967_18510	COG1970	mechanosensitive ion channel activity
ES967_18515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ES967_18520	COG0457	Tetratricopeptide repeat
ES967_18525	COG4786	Flagellar basal body rod
ES967_18530	COG4786	Flagellar basal body rod
ES967_18535	COG1077	Cell shape determining protein MreB Mrl
ES967_18540	COG1609	Transcriptional regulator
ES967_18550	COG1846	Transcriptional regulator
ES967_18555	COG2814	Major facilitator Superfamily
ES967_18560	COG3420	alginic acid biosynthetic process
ES967_18565	COG1953	Uracil, thiamine, allantoin
ES967_18570	COG0477	Major facilitator Superfamily
ES967_18575	COG1335	isochorismatase
ES967_18585	COG0004	ammonium transporteR
ES967_18590	COG0347	Belongs to the P(II) protein family
ES967_18595	COG0671	phosphoesterase, PA-phosphatase related
ES967_18605	COG0739	heme binding
ES967_18610	COG1247	-acetyltransferase
ES967_18630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ES967_18635	COG0789	Transcriptional regulator
ES967_18645	COG2910	NAD(P)H-binding
ES967_18650	COG1959	2 iron, 2 sulfur cluster binding
ES967_18655	COG0804	urea catabolic process
ES967_18660	COG0832	Belongs to the urease beta subunit family
ES967_18665	COG0831	urea catabolic process
ES967_18680	COG3237	CsbD-like
ES967_18685	COG1994	Peptidase M50
ES967_18690	COG0457	Tetratricopeptide repeat
ES967_18695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ES967_18700	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ES967_18710	COG2304	oxidoreductase activity
ES967_18720	COG2304	oxidoreductase activity
ES967_18725	COG2385	sporulation resulting in formation of a cellular spore
ES967_18730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ES967_18740	COG4836	Membrane
ES967_18750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ES967_18755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ES967_18760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ES967_18765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ES967_18770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ES967_18775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ES967_18780	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ES967_18785	COG0356	it plays a direct role in the translocation of protons across the membrane
ES967_18795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ES967_18800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ES967_18805	COG4475	Protein of unknown function (DUF436)
ES967_18810	COG0698	ribose 5-phosphate isomerase
ES967_18815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ES967_18820	COG1971	Probably functions as a manganese efflux pump
ES967_18825	COG0009	L-threonylcarbamoyladenylate synthase
ES967_18830	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ES967_18850	COG2890	protein-(glutamine-N5) methyltransferase activity
ES967_18855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ES967_18860	COG0346	lactoylglutathione lyase activity
ES967_18865	COG0789	Transcriptional regulator
ES967_18870	COG0679	Auxin Efflux Carrier
ES967_18875	COG0281	malic enzyme
ES967_18880	COG1435	thymidine kinase activity
ES967_18885	COG0254	rRNA binding
ES967_18890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ES967_18900	COG1494	fructose-1,6-bisphosphatase
ES967_18905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ES967_18910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ES967_18915	COG0191	fructose-bisphosphate aldolase activity
ES967_18920	COG2204	response regulator
ES967_18925	COG4821	SIS domain
ES967_18930	COG0504	CTP synthase activity
ES967_18935	COG3343	RNA polymerase activity
ES967_18940	COG1960	acyl-CoA dehydrogenase activity
ES967_18945	COG0247	lactate metabolic process
ES967_18945	COG2181	nitrate reductase activity
ES967_18950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ES967_18955	COG4294	response to UV
ES967_18965	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ES967_18970	COG1132	(ABC) transporter
ES967_18975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ES967_18990	COG2181	nitrate reductase activity
ES967_18995	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ES967_19000	COG1140	nitrate reductase beta subunit
ES967_19005	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ES967_19015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ES967_19025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ES967_19030	COG2223	nitrite transmembrane transporter activity
ES967_19035	COG0018	arginyl-trna synthetase
ES967_19040	COG4506	Protein conserved in bacteria
ES967_19055	COG0535	radical SAM domain protein
ES967_19065	COG1131	(ABC) transporter
ES967_19070	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ES967_19075	COG0612	Peptidase, M16
ES967_19080	COG0612	Peptidase, M16
ES967_19090	COG3391	amine dehydrogenase activity
ES967_19095	COG3391	amine dehydrogenase activity
ES967_19105	COG0457	Tetratricopeptide repeat
ES967_19120	COG0010	Belongs to the arginase family
ES967_19125	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ES967_19130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ES967_19145	COG1994	Peptidase M50
ES967_19150	COG1942	4-Oxalocrotonate Tautomerase
ES967_19155	COG1846	Transcriptional regulator
ES967_19170	COG0477	Major facilitator Superfamily
ES967_19175	COG1959	2 iron, 2 sulfur cluster binding
ES967_19180	COG3465	dGTPase activity
ES967_19185	COG1078	dGTPase activity
ES967_19190	COG4844	belongs to the
ES967_19200	COG0697	spore germination
ES967_19205	COG0095	Lipoate-protein ligase
ES967_19210	COG0583	DNA-binding transcription factor activity
ES967_19215	COG0280	phosphate acetyltransferase
ES967_19225	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_19230	COG0436	Aminotransferase
ES967_19235	COG2814	Major facilitator Superfamily
ES967_19240	COG0151	Belongs to the GarS family
ES967_19245	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_19250	COG1917	Cupin 2, conserved barrel domain protein
ES967_19255	COG0077	Prephenate dehydratase
ES967_19260	COG2814	Major facilitator Superfamily
ES967_19265	COG0833	amino acid
ES967_19270	COG4187	Peptidase family M20/M25/M40
ES967_19275	COG1012	belongs to the aldehyde dehydrogenase family
ES967_19280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ES967_19290	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ES967_19295	COG1091	dTDP-4-dehydrorhamnose reductase activity
ES967_19300	COG1088	dTDP-glucose 4,6-dehydratase activity
ES967_19305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ES967_19310	COG3980	spore coat polysaccharide biosynthesis protein
ES967_19315	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
ES967_19320	COG2089	acid synthase
ES967_19325	COG0456	acetyltransferase
ES967_19330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ES967_19335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ES967_19340	COG0463	Glycosyl transferase, family 2
ES967_19355	COG2363	Small membrane protein
ES967_19360	COG2233	PERMEase
ES967_19370	COG1012	belongs to the aldehyde dehydrogenase family
ES967_19375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ES967_19380	COG1216	Glycosyl transferase, family 2
ES967_19395	COG1695	Transcriptional regulator
ES967_19400	COG0351	phosphomethylpyrimidine kinase
ES967_19410	COG1621	beta-fructofuranosidase activity
ES967_19415	COG1263	PTS System
ES967_19415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_19420	COG2116	formate transmembrane transporter activity
ES967_19425	COG3711	transcriptional antiterminator
ES967_19435	COG1404	Belongs to the peptidase S8 family
ES967_19440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ES967_19445	COG0778	Nitroreductase
ES967_19450	COG0772	Belongs to the SEDS family
ES967_19460	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ES967_19465	COG1845	cytochrome c oxidase, subunit III
ES967_19470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ES967_19475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ES967_19480	COG2261	transglycosylase associated protein
ES967_19485	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ES967_19490	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ES967_19495	COG2246	polysaccharide biosynthetic process
ES967_19500	COG1309	transcriptional regulator
ES967_19510	COG3162	membrane
ES967_19515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ES967_19520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ES967_19525	COG2837	iron assimilation
ES967_19530	COG2822	iron ion transport
ES967_19535	COG0672	)-iron permease
ES967_19540	COG0352	thiamine-phosphate diphosphorylase activity
ES967_19545	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ES967_19550	COG0583	DNA-binding transcription factor activity
ES967_19555	COG1380	Effector of murein hydrolase LrgA
ES967_19560	COG1346	cytolysis
ES967_19565	COG2814	Major facilitator Superfamily
ES967_19570	COG4895	conserved protein (DUF2196)
ES967_19575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ES967_19580	COG0346	lactoylglutathione lyase activity
ES967_19590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES967_19600	COG1263	PTS System
ES967_19600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_19605	COG3711	transcriptional antiterminator
ES967_19610	COG1442	glycosyl transferase family 8
ES967_19615	COG5522	Integral membrane protein (intg_mem_TP0381)
ES967_19620	COG1846	Transcriptional regulator
ES967_19625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ES967_19630	COG2234	aminopeptidase activity
ES967_19645	COG2814	Major facilitator Superfamily
ES967_19650	COG2357	RelA SpoT domain protein
ES967_19655	COG1575	Belongs to the MenA family. Type 1 subfamily
ES967_19675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ES967_19680	COG1696	Membrane protein involved in D-alanine export
ES967_19685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ES967_19690	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ES967_19695	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ES967_19700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ES967_19705	COG1486	melibiose metabolic process
ES967_19710	COG1447	Phosphotransferase system cellobiose-specific component IIA
ES967_19715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES967_19720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES967_19725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES967_19725	COG3711	transcriptional antiterminator
ES967_19735	COG2094	Belongs to the DNA glycosylase MPG family
ES967_19740	COG0753	catalase activity
ES967_19745	COG2814	Major facilitator Superfamily
ES967_19750	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ES967_19755	COG1131	(ABC) transporter
ES967_19775	COG1595	DNA-templated transcription, initiation
ES967_19780	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ES967_19785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ES967_19790	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ES967_19795	COG4988	ABC transporter
ES967_19800	COG1294	oxidase, subunit
ES967_19805	COG1271	oxidase subunit
ES967_19810	COG3493	citrate carrier protein
ES967_19815	COG0501	Belongs to the peptidase M48B family
ES967_19825	COG0726	polysaccharide deacetylase
ES967_19830	COG3842	ATPase activity
ES967_19835	COG2508	Transcriptional regulator
ES967_19840	COG1012	belongs to the aldehyde dehydrogenase family
ES967_19845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ES967_19860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ES967_19870	COG4585	Histidine kinase
ES967_19875	COG2197	response regulator
ES967_19880	COG2195	Cleaves the N-terminal amino acid of tripeptides
ES967_19890	COG4894	glucomannan catabolic process
ES967_19895	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ES967_19900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ES967_19905	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_19910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ES967_19915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ES967_19920	COG2610	gluconate transmembrane transporter activity
ES967_19925	COG0500	methyltransferase
ES967_19930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ES967_19945	COG0693	protein deglycase activity
ES967_19945	COG0753	catalase activity
ES967_19950	COG2851	Citrate transporter
ES967_19955	COG2273	Hydrolase Family 16
ES967_19960	COG3711	transcriptional antiterminator
ES967_19970	COG2270	Major facilitator Superfamily
ES967_19975	COG0513	Belongs to the DEAD box helicase family
ES967_19980	COG3401	FG-GAP repeat protein
ES967_19980	COG2755	lipolytic protein G-D-S-L family
ES967_20040	COG3209	COG3209 Rhs family protein
ES967_20045	COG0697	spore germination
ES967_20050	COG0589	response to stress
ES967_20055	COG2723	6-phospho-beta-galactosidase activity
ES967_20060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_20060	COG1263	PTS System
ES967_20060	COG2190	(PTS) system
ES967_20075	COG5444	nuclease activity
ES967_20090	COG3507	Belongs to the glycosyl hydrolase 43 family
ES967_20105	COG2986	histidine ammonia-lyase
ES967_20110	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ES967_20115	COG1228	amidohydrolase
ES967_20120	COG0010	Belongs to the arginase family
ES967_20125	COG0833	amino acid
ES967_20130	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ES967_20135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ES967_20140	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ES967_20145	COG2390	Transcriptional regulator
ES967_20155	COG3192	ethanolamine utilization protein
ES967_20160	COG2079	MmgE PrpD family protein
ES967_20170	COG1126	abc transporter atp-binding protein
ES967_20175	COG0765	amino acid transport
ES967_20180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES967_20200	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ES967_20205	COG0561	phosphatase activity
ES967_20235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ES967_20240	COG5294	Protein conserved in bacteria
ES967_20245	COG0577	efflux transmembrane transporter activity
ES967_20250	COG1136	(ABC) transporter
ES967_20255	COG2205	protein histidine kinase activity
ES967_20260	COG0745	RESPONSE REGULATOR receiver
ES967_20265	COG0191	fructose-bisphosphate aldolase activity
ES967_20270	COG1082	Xylose isomerase domain protein TIM barrel
ES967_20275	COG1082	Xylose isomerase domain protein TIM barrel
ES967_20280	COG0673	inositol 2-dehydrogenase activity
ES967_20285	COG2814	Major facilitator Superfamily
ES967_20290	COG1082	Xylose isomerase domain protein TIM barrel
ES967_20295	COG3962	Belongs to the TPP enzyme family
ES967_20300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ES967_20305	COG3718	enzyme involved in inositol metabolism
ES967_20310	COG1012	belongs to the aldehyde dehydrogenase family
ES967_20315	COG1349	DNA-binding transcription factor activity
ES967_20320	COG0667	Aldo Keto reductase
ES967_20335	COG2814	Major facilitator Superfamily
ES967_20340	COG0326	Molecular chaperone. Has ATPase activity
ES967_20350	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_20355	COG1309	transcriptional regulator
ES967_20360	COG1012	belongs to the aldehyde dehydrogenase family
ES967_20370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ES967_20380	COG1714	RDD family
ES967_20385	COG2311	Membrane
ES967_20390	COG1917	Cupin 2, conserved barrel domain protein
ES967_20395	COG1309	transcriptional regulator
ES967_20400	COG1028	Short-chain dehydrogenase reductase Sdr
ES967_20405	COG1846	Transcriptional regulator
ES967_20410	COG1380	Effector of murein hydrolase LrgA
ES967_20415	COG1346	cytolysis
ES967_20420	COG5039	Polysaccharide pyruvyl transferase
ES967_20425	COG1929	Belongs to the glycerate kinase type-1 family
ES967_20430	COG1802	Transcriptional regulator
ES967_20435	COG1070	Carbohydrate kinase
ES967_20440	COG2610	gluconate transmembrane transporter activity
ES967_20445	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ES967_20450	COG0450	alkyl hydroperoxide reductase
ES967_20455	COG3634	alkyl hydroperoxide reductase activity
ES967_20460	COG2723	6-phospho-beta-galactosidase activity
ES967_20465	COG2190	(PTS) system
ES967_20470	COG2190	(PTS) system
ES967_20470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES967_20470	COG1263	PTS System
ES967_20475	COG2188	Transcriptional regulator
ES967_20490	COG1131	(ABC) transporter
ES967_20495	COG1994	Peptidase M50
ES967_20500	COG0535	radical SAM domain protein
ES967_20510	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ES967_20520	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ES967_20535	COG1063	alcohol dehydrogenase
ES967_20555	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ES967_20560	COG0456	acetyltransferase
ES967_20565	COG0457	Tetratricopeptide repeat
ES967_20575	COG0010	Belongs to the arginase family
ES967_20580	COG0833	amino acid
ES967_20585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ES967_20590	COG3829	transcription factor binding
ES967_20595	COG5002	protein histidine kinase activity
ES967_20620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ES967_20625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ES967_20630	COG4853	Protein conserved in bacteria
ES967_20635	COG4863	YycH protein
ES967_20640	COG5002	protein histidine kinase activity
ES967_20645	COG0745	RESPONSE REGULATOR receiver
ES967_20675	COG0346	lactoylglutathione lyase activity
ES967_20680	COG0305	Participates in initiation and elongation during chromosome replication
ES967_20700	COG2807	transmembrane transport
ES967_20705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ES967_20710	COG0359	binds to the 23S rRNA
ES967_20715	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ES967_20720	COG4241	membrane
ES967_20730	COG5577	PFAM Coat F domain
ES967_20735	COG1733	regulation of RNA biosynthetic process
ES967_20740	COG1227	inorganic diphosphatase activity
ES967_20755	COG2271	Major facilitator Superfamily
ES967_20770	COG4319	ketosteroid isomerase
ES967_20775	COG1357	PFAM Pentapeptide repeats (8 copies)
ES967_20780	COG2814	Major facilitator Superfamily
ES967_20785	COG0583	DNA-binding transcription factor activity
ES967_20790	COG2153	protein acetylation
ES967_20805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ES967_20810	COG1846	Transcriptional regulator
ES967_20815	COG2153	protein acetylation
ES967_20820	COG2364	Membrane
ES967_20825	COG0456	acetyltransferase
ES967_20830	COG2315	Protein conserved in bacteria
ES967_20835	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ES967_20845	COG2814	Major facilitator Superfamily
ES967_20855	COG1331	Highly conserved protein containing a thioredoxin domain
ES967_20870	COG0789	Transcriptional regulator
ES967_20875	COG0697	spore germination
ES967_20885	COG1280	lysine exporter protein (LysE YggA)
ES967_20890	COG1331	Highly conserved protein containing a thioredoxin domain
ES967_20895	COG1331	Highly conserved protein containing a thioredoxin domain
ES967_20900	COG1266	CAAX protease self-immunity
ES967_20905	COG0477	Major facilitator Superfamily
ES967_20905	COG2814	Major facilitator Superfamily
ES967_20910	COG0110	maltose O-acetyltransferase activity
ES967_20915	COG0346	lactoylglutathione lyase activity
ES967_20920	COG1609	Transcriptional regulator
ES967_20925	COG0708	Exodeoxyribonuclease III
ES967_20930	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ES967_20935	COG0629	single-stranded DNA binding
ES967_20940	COG0360	Binds together with S18 to 16S ribosomal RNA
ES967_20945	COG0012	GTP binding
ES967_20950	COG0243	molybdopterin cofactor binding
ES967_20955	COG4481	Protein conserved in bacteria
ES967_20960	COG3949	Membrane
ES967_20970	COG1475	DNA binding
ES967_20975	COG1192	Involved in chromosome partitioning
ES967_20985	COG1475	DNA binding
ES967_20990	COG0357	Ribosomal RNA small subunit methyltransferase G
ES967_20995	COG0445	tRNA wobble uridine modification
ES967_21000	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ES967_21005	COG1847	R3H domain protein
ES967_21010	COG0706	membrane insertase activity
ES967_21015	COG0594	ribonuclease P activity
ES967_21020	COG0230	Belongs to the bacterial ribosomal protein bL34 family