locus-tag	class	description
ETA18_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ETA18_00010	COG0592	DNA-directed DNA polymerase activity
ETA18_00015	COG2501	S4 domain
ETA18_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ETA18_00030	COG0187	DNA topoisomerase II activity
ETA18_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETA18_00070	COG0517	IMP dehydrogenase activity
ETA18_00070	COG0516	GMP reductase activity
ETA18_00075	COG1686	Belongs to the peptidase S11 family
ETA18_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ETA18_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ETA18_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ETA18_00100	COG1428	Deoxynucleoside kinase
ETA18_00105	COG1428	Deoxynucleoside kinase
ETA18_00110	COG1388	LysM domain
ETA18_00110	COG3858	chitin binding
ETA18_00115	COG1335	isochorismatase
ETA18_00120	COG0590	tRNA wobble adenosine to inosine editing
ETA18_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ETA18_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ETA18_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ETA18_00175	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
ETA18_00180	COG3853	Toxic anion resistance protein (TelA)
ETA18_00185	COG1982	Orn Lys Arg decarboxylase major
ETA18_00190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ETA18_00195	COG3870	Protein conserved in bacteria
ETA18_00200	COG1728	Protein conserved in bacteria
ETA18_00205	COG0470	DNA polymerase III
ETA18_00210	COG1774	PSP1 C-terminal conserved region
ETA18_00215	COG4467	Involved in initiation control of chromosome replication
ETA18_00220	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ETA18_00225	COG2827	Endonuclease containing a URI domain
ETA18_00230	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ETA18_00235	COG2002	toxin-antitoxin pair type II binding
ETA18_00240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETA18_00240	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETA18_00245	COG0084	hydrolase, TatD family'
ETA18_00250	COG3583	domain protein
ETA18_00250	COG3584	3D domain protein
ETA18_00255	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ETA18_00260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ETA18_00270	COG4466	Protein conserved in bacteria
ETA18_00280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ETA18_00285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETA18_00290	COG0251	oxidation-reduction process
ETA18_00295	COG2088	sporulation resulting in formation of a cellular spore
ETA18_00300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ETA18_00305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ETA18_00310	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ETA18_00315	COG0193	aminoacyl-tRNA hydrolase activity
ETA18_00325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETA18_00330	COG2002	toxin-antitoxin pair type II binding
ETA18_00335	COG2244	polysaccharide biosynthetic process
ETA18_00340	COG3956	TIGRFAM MazG family protein
ETA18_00345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ETA18_00360	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ETA18_00365	COG1098	S1 RNA binding domain
ETA18_00380	COG2208	phosphoserine phosphatase activity
ETA18_00385	COG2304	oxidoreductase activity
ETA18_00390	COG0515	serine threonine protein kinase
ETA18_00395	COG0037	tRNA processing
ETA18_00405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETA18_00410	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ETA18_00415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ETA18_00420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETA18_00425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETA18_00430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETA18_00435	COG0512	Glutamine amidotransferase of anthranilate synthase
ETA18_00440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETA18_00445	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ETA18_00450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ETA18_00455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ETA18_00460	COG1396	sequence-specific DNA binding
ETA18_00465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETA18_00470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ETA18_00560	COG4463	regulation of RNA biosynthetic process
ETA18_00565	COG3880	PFAM UvrB UvrC protein
ETA18_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ETA18_00575	COG0542	response to heat
ETA18_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ETA18_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ETA18_00590	COG4956	integral membrane protein (PIN domain superfamily)
ETA18_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ETA18_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ETA18_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ETA18_00615	COG1045	serine acetyltransferase
ETA18_00620	COG0215	cysteine-tRNA ligase activity
ETA18_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ETA18_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETA18_00635	COG3688	RNA-binding protein containing a PIN domain
ETA18_00640	COG1595	DNA-templated transcription, initiation
ETA18_00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ETA18_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ETA18_00655	COG0250	Participates in transcription elongation, termination and antitermination
ETA18_00660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ETA18_00665	COG0081	regulation of translation
ETA18_00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ETA18_00675	COG0222	ribosome binding
ETA18_00680	COG2813	Specifically methylates the guanine in position
ETA18_00685	COG0085	RNA polymerase activity
ETA18_00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ETA18_00695	COG1358	cellular component organization or biogenesis
ETA18_00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ETA18_00705	COG0049	tRNA binding
ETA18_00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETA18_00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ETA18_00720	COG0596	Alpha beta hydrolase
ETA18_00725	COG0051	transcription antitermination factor activity, RNA binding
ETA18_00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ETA18_00735	COG0088	Forms part of the polypeptide exit tunnel
ETA18_00740	COG0089	rRNA binding
ETA18_00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ETA18_00750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ETA18_00755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ETA18_00760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ETA18_00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ETA18_00770	COG0255	Belongs to the universal ribosomal protein uL29 family
ETA18_00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ETA18_00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ETA18_00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ETA18_00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ETA18_00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ETA18_00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ETA18_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ETA18_00820	COG1841	ribosomal large subunit assembly
ETA18_00825	COG0200	Binds to the 23S rRNA
ETA18_00830	COG0201	protein transport
ETA18_00835	COG0563	adenylate kinase activity
ETA18_00840	COG0024	Methionine aminopeptidase
ETA18_00845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
ETA18_00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ETA18_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ETA18_00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ETA18_00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ETA18_00870	COG0202	RNA polymerase activity
ETA18_00875	COG0203	ribosomal protein L17
ETA18_00880	COG1122	ATPase activity
ETA18_00885	COG1122	ATPase activity
ETA18_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETA18_00895	COG0101	tRNA pseudouridine synthase activity
ETA18_00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ETA18_00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ETA18_00910	COG2226	methyltransferase
ETA18_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA18_00925	COG0489	protein tyrosine kinase activity
ETA18_00935	COG2194	sulfuric ester hydrolase activity
ETA18_00940	COG0726	polysaccharide deacetylase
ETA18_01025	COG0659	secondary active sulfate transmembrane transporter activity
ETA18_01030	COG0385	Bile acid
ETA18_01035	COG2819	hydrolase of the alpha beta superfamily
ETA18_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA18_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA18_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA18_01055	COG2207	Transcriptional regulator
ETA18_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA18_01060	COG3876	Protein conserved in bacteria
ETA18_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
ETA18_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETA18_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_01075	COG1263	PTS System
ETA18_01080	COG1737	Transcriptional regulator
ETA18_01085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ETA18_01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA18_01125	COG1595	DNA-templated transcription, initiation
ETA18_01130	COG5662	AntiSigma factor
ETA18_01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETA18_01140	COG4856	YbbR-like protein
ETA18_01145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETA18_01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ETA18_01160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETA18_01165	COG3002	Belongs to the UPF0753 family
ETA18_01170	COG0288	reversible hydration of carbon dioxide
ETA18_01180	COG5609	conserved protein (DUF2294)
ETA18_01185	COG0640	Transcriptional regulator
ETA18_01190	COG2814	Major facilitator Superfamily
ETA18_01205	COG0535	radical SAM domain protein
ETA18_01210	COG1266	CAAX protease self-immunity
ETA18_01215	COG1131	(ABC) transporter
ETA18_01225	COG1413	lyase activity
ETA18_01230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA18_01235	COG0596	Alpha beta hydrolase
ETA18_01240	COG0745	RESPONSE REGULATOR receiver
ETA18_01245	COG0642	Histidine kinase
ETA18_01255	COG0515	serine threonine protein kinase
ETA18_01270	COG1113	amino acid transport
ETA18_01285	COG2602	Beta-lactamase
ETA18_01290	COG2124	cytochrome p450
ETA18_01300	COG0531	amino acid
ETA18_01305	COG0584	glycerophosphoryl diester phosphodiesterase
ETA18_01310	COG2271	Major facilitator Superfamily
ETA18_01325	COG1846	Transcriptional regulator
ETA18_01325	COG0456	acetyltransferase
ETA18_01330	COG2271	Major facilitator Superfamily
ETA18_01340	COG0697	spore germination
ETA18_01345	COG2207	Transcriptional regulator
ETA18_01345	COG1917	Cupin 2, conserved barrel domain protein
ETA18_01370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ETA18_01375	COG3591	Belongs to the peptidase S1B family
ETA18_01385	COG0596	Alpha beta hydrolase
ETA18_01390	COG1183	phosphatidylcholine synthase activity
ETA18_01395	COG0586	Pfam SNARE associated Golgi protein
ETA18_01400	COG0688	phosphatidylethanolamine metabolic process
ETA18_01410	COG2312	Erythromycin esterase
ETA18_01415	COG2207	Transcriptional regulator
ETA18_01425	COG1301	dicarboxylic acid transport
ETA18_01430	COG2190	(PTS) system
ETA18_01430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_01430	COG1263	PTS System
ETA18_01435	COG0363	glucosamine-6-phosphate deaminase activity
ETA18_01450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETA18_01455	COG0833	amino acid
ETA18_01460	COG2040	homocysteine
ETA18_01470	COG1115	amino acid carrier protein
ETA18_01475	COG2066	Belongs to the glutaminase family
ETA18_01480	COG4191	Histidine kinase
ETA18_01485	COG0784	Response regulator, receiver
ETA18_01495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETA18_01500	COG1012	belongs to the aldehyde dehydrogenase family
ETA18_01505	COG2271	Major facilitator Superfamily
ETA18_01510	COG4948	Mandelate Racemase Muconate Lactonizing
ETA18_01515	COG2186	Transcriptional regulator
ETA18_01520	COG2721	sulfolactate sulfo-lyase activity
ETA18_01530	COG3173	Aminoglycoside phosphotransferase
ETA18_01540	COG0697	spore germination
ETA18_01545	COG0745	RESPONSE REGULATOR receiver
ETA18_01550	COG2205	protein histidine kinase activity
ETA18_01555	COG1131	(ABC) transporter
ETA18_01575	COG3773	Cell wall hydrolase
ETA18_01580	COG2304	oxidoreductase activity
ETA18_01590	COG3540	Alkaline phosphatase
ETA18_01595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETA18_01600	COG0805	protein transport
ETA18_01605	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ETA18_01610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETA18_01615	COG0477	Major facilitator Superfamily
ETA18_01620	COG1309	transcriptional regulator
ETA18_01625	COG0252	asparaginase activity
ETA18_01630	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ETA18_01635	COG1714	RDD family
ETA18_01640	COG3012	SEC-C Motif Domain Protein
ETA18_01640	COG1405	negative regulation of cell septum assembly
ETA18_01645	COG3290	protein histidine kinase activity
ETA18_01650	COG3279	Response regulator of the LytR AlgR family
ETA18_01655	COG4555	ABC transporter
ETA18_01660	COG1668	transmembrane transport
ETA18_01665	COG0667	Aldo Keto reductase
ETA18_01680	COG1595	DNA-templated transcription, initiation
ETA18_01690	COG1595	DNA-templated transcription, initiation
ETA18_01695	COG1876	peptidase activity
ETA18_01700	COG0457	Tetratricopeptide repeat
ETA18_01705	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_01710	COG0366	Alpha amylase catalytic
ETA18_01715	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETA18_01720	COG1121	(ABC) transporter
ETA18_01725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETA18_01730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETA18_01735	COG2310	stress, protein
ETA18_01740	COG2310	stress, protein
ETA18_01745	COG2310	stress, protein
ETA18_01750	COG0861	Integral membrane protein TerC family
ETA18_01760	COG3853	Toxic anion resistance protein (TelA)
ETA18_01765	COG0477	Major facilitator Superfamily
ETA18_01775	COG2814	Major facilitator Superfamily
ETA18_01780	COG0640	Transcriptional regulator
ETA18_01785	COG4175	Glycine betaine
ETA18_01785	COG0517	IMP dehydrogenase activity
ETA18_01790	COG4176	ABC-type proline glycine betaine transport system permease component
ETA18_01795	COG2113	Glycine betaine
ETA18_01800	COG1473	amidohydrolase
ETA18_01805	COG1288	antiporter activity
ETA18_01815	COG0366	Alpha amylase catalytic
ETA18_01820	COG0039	L-malate dehydrogenase activity
ETA18_01825	COG1620	l-lactate permease
ETA18_01830	COG2814	Major facilitator Superfamily
ETA18_01835	COG1846	Transcriptional regulator
ETA18_01840	COG1280	lysine exporter protein (LysE YggA)
ETA18_01845	COG3403	YqcI/YcgG family
ETA18_01850	COG1113	amino acid transport
ETA18_01855	COG3665	Urea carboxylase-associated protein
ETA18_01860	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ETA18_01865	COG1660	Displays ATPase and GTPase activities
ETA18_01870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ETA18_01875	COG2226	methyltransferase
ETA18_01880	COG0583	DNA-binding transcription factor activity
ETA18_01885	COG3458	cephalosporin-C deacetylase activity
ETA18_01890	COG3541	Predicted nucleotidyltransferase
ETA18_01895	COG0506	proline dehydrogenase activity
ETA18_01900	COG1012	belongs to the aldehyde dehydrogenase family
ETA18_01905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETA18_01910	COG2508	Transcriptional regulator
ETA18_01915	COG3689	TIGRFAM TIGR03943 family protein
ETA18_01920	COG0701	Predicted permease
ETA18_01925	COG2267	carboxylic ester hydrolase activity
ETA18_01930	COG0492	ferredoxin-NADP+ reductase activity
ETA18_01935	COG1587	Uroporphyrinogen-III synthase
ETA18_01935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETA18_01940	COG2146	nitrite reductase [NAD(P)H] activity
ETA18_01945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETA18_01950	COG0243	molybdopterin cofactor binding
ETA18_01955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETA18_01960	COG2223	nitrite transmembrane transporter activity
ETA18_01965	COG1469	GTP cyclohydrolase I activity
ETA18_01970	COG1376	ErfK ybiS ycfS ynhG family protein
ETA18_01980	COG0523	cobalamin synthesis protein
ETA18_01985	COG0765	amino acid transport
ETA18_01990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETA18_02000	COG1714	RDD family
ETA18_02010	COG1846	Transcriptional regulator
ETA18_02020	COG3842	ATPase activity
ETA18_02025	COG2723	6-phospho-beta-galactosidase activity
ETA18_02035	COG3209	COG3209 Rhs family protein
ETA18_02040	COG0840	transmembrane signaling receptor activity
ETA18_02040	COG3290	protein histidine kinase activity
ETA18_02045	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ETA18_02050	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ETA18_02055	COG1733	regulation of RNA biosynthetic process
ETA18_02060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_02065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_02070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_02075	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ETA18_02080	COG2814	Major facilitator Superfamily
ETA18_02090	COG0697	spore germination
ETA18_02095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA18_02105	COG2364	Membrane
ETA18_02110	COG1126	abc transporter atp-binding protein
ETA18_02115	COG0765	amino acid transport
ETA18_02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETA18_02125	COG0583	DNA-binding transcription factor activity
ETA18_02130	COG0163	prenyltransferase activity
ETA18_02135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ETA18_02150	COG0596	Alpha beta hydrolase
ETA18_02155	COG3104	oligopeptide transport
ETA18_02160	COG5434	Belongs to the glycosyl hydrolase 28 family
ETA18_02170	COG0697	spore germination
ETA18_02180	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ETA18_02185	COG1136	(ABC) transporter
ETA18_02190	COG0577	efflux transmembrane transporter activity
ETA18_02195	COG0745	RESPONSE REGULATOR receiver
ETA18_02200	COG5002	protein histidine kinase activity
ETA18_02200	COG3850	Histidine kinase
ETA18_02205	COG0457	Tetratricopeptide repeat
ETA18_02225	COG0527	aspartate kinase activity
ETA18_02230	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA18_02235	COG4605	iron ion homeostasis
ETA18_02240	COG4604	ABC transporter, ATP-binding protein
ETA18_02245	COG4607	ABC-type enterochelin transport system periplasmic component
ETA18_02250	COG2814	Major facilitator Superfamily
ETA18_02255	COG1309	transcriptional regulator
ETA18_02260	COG0778	Nitroreductase
ETA18_02265	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETA18_02270	COG0640	Transcriptional regulator
ETA18_02275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA18_02280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ETA18_02285	COG1012	belongs to the aldehyde dehydrogenase family
ETA18_02290	COG4975	Glucose uptake
ETA18_02295	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_02300	COG4549	nuclear export factor GLE1
ETA18_02305	COG2372	response to copper ion
ETA18_02305	COG1276	copper resistance
ETA18_02310	COG1349	DNA-binding transcription factor activity
ETA18_02320	COG2213	PTS system mannitol-specific
ETA18_02325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA18_02330	COG0246	Mannitol dehydrogenase
ETA18_02335	COG0473	3-isopropylmalate dehydrogenase activity
ETA18_02340	COG0681	Belongs to the peptidase S26 family
ETA18_02345	COG0412	Dienelactone hydrolase
ETA18_02350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETA18_02360	COG0561	phosphatase activity
ETA18_02365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ETA18_02370	COG1914	H( )-stimulated, divalent metal cation uptake system
ETA18_02375	COG4336	lyase activity
ETA18_02380	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ETA18_02385	COG1984	allophanate hydrolase subunit 2
ETA18_02390	COG1414	Transcriptional regulator
ETA18_02395	COG2755	lipolytic protein G-D-S-L family
ETA18_02405	COG2329	Antibiotic biosynthesis monooxygenase
ETA18_02410	COG0768	penicillin binding
ETA18_02415	COG4989	oxidoreductase activity
ETA18_02420	COG3711	transcriptional antiterminator
ETA18_02425	COG0318	PFAM AMP-dependent synthetase and ligase
ETA18_02430	COG2226	methyltransferase
ETA18_02435	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_02440	COG1917	Cupin 2, conserved barrel domain protein
ETA18_02445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA18_02450	COG3871	stress protein (general stress protein 26)
ETA18_02460	COG2814	Major facilitator Superfamily
ETA18_02465	COG1522	sequence-specific DNA binding
ETA18_02470	COG0551	DNA topoisomerase type I activity
ETA18_02470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETA18_02475	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ETA18_02480	COG3706	GGDEF domain
ETA18_02485	COG5298	Protein conserved in bacteria
ETA18_02490	COG1215	transferase activity, transferring glycosyl groups
ETA18_02500	COG0531	amino acid
ETA18_02505	COG0494	nUDIX hydrolase
ETA18_02510	COG0028	Belongs to the TPP enzyme family
ETA18_02520	COG1914	H( )-stimulated, divalent metal cation uptake system
ETA18_02525	COG2261	transglycosylase associated protein
ETA18_02530	COG4876	unkown
ETA18_02535	COG2217	Heavy metal translocating P-type atpase
ETA18_02540	COG3729	General stress protein
ETA18_02545	COG0662	Cupin 2, conserved barrel domain protein
ETA18_02550	COG2329	Antibiotic biosynthesis monooxygenase
ETA18_02555	COG3546	catalase activity
ETA18_02560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ETA18_02565	COG3290	protein histidine kinase activity
ETA18_02570	COG4565	transcriptional regulatory protein
ETA18_02575	COG1301	dicarboxylic acid transport
ETA18_02580	COG0628	permease
ETA18_02585	COG1131	(ABC) transporter
ETA18_02590	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETA18_02600	COG1960	acyl-CoA dehydrogenase activity
ETA18_02615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETA18_02620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA18_02625	COG1181	Belongs to the D-alanine--D-alanine ligase family
ETA18_02630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETA18_02640	COG0513	Belongs to the DEAD box helicase family
ETA18_02645	COG3402	PFAM membrane-flanked domain
ETA18_02650	COG3428	Bacterial PH domain
ETA18_02655	COG0705	Rhomboid family
ETA18_02660	COG0736	holo-[acyl-carrier-protein] synthase activity
ETA18_02665	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ETA18_02670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ETA18_02675	COG0864	Transcriptional regulator
ETA18_02680	COG2337	Toxic component of a toxin-antitoxin (TA) module
ETA18_02685	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA18_02690	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA18_02695	COG2172	sigma factor antagonist activity
ETA18_02700	COG2208	phosphoserine phosphatase activity
ETA18_02705	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA18_02710	COG2172	sigma factor antagonist activity
ETA18_02715	COG1191	sigma factor activity
ETA18_02720	COG2208	phosphoserine phosphatase activity
ETA18_02725	COG2183	response to ionizing radiation
ETA18_02735	COG3091	SprT-like family
ETA18_02785	COG0583	DNA-binding transcription factor activity
ETA18_02790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA18_02800	COG5444	nuclease activity
ETA18_02810	COG1476	TRANSCRIPTIONal
ETA18_02820	COG3239	Fatty acid desaturase
ETA18_02825	COG1278	Cold shock
ETA18_02830	COG1329	Transcriptional regulator
ETA18_02840	COG0697	spore germination
ETA18_02845	COG2207	Transcriptional regulator
ETA18_02845	COG1917	Cupin 2, conserved barrel domain protein
ETA18_02850	COG0697	spore germination
ETA18_02855	COG2207	Transcriptional regulator
ETA18_02855	COG3708	Transcriptional regulator
ETA18_02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA18_02865	COG0477	Major facilitator Superfamily
ETA18_02875	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ETA18_02895	COG1309	transcriptional regulator
ETA18_02900	COG0697	spore germination
ETA18_02905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA18_02910	COG2030	dehydratase
ETA18_02915	COG3545	Serine hydrolase
ETA18_02920	COG1733	regulation of RNA biosynthetic process
ETA18_02925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA18_02930	COG1733	regulation of RNA biosynthetic process
ETA18_02935	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETA18_02940	COG2814	Major facilitator Superfamily
ETA18_02945	COG1309	transcriptional regulator
ETA18_02950	COG0640	Transcriptional regulator
ETA18_02955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ETA18_02965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA18_02985	COG5002	protein histidine kinase activity
ETA18_02990	COG0745	RESPONSE REGULATOR receiver
ETA18_02995	COG0697	spore germination
ETA18_03000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA18_03005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETA18_03010	COG0640	Transcriptional regulator
ETA18_03015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ETA18_03030	COG4585	Histidine kinase
ETA18_03035	COG2197	response regulator
ETA18_03040	COG2409	Drug exporters of the RND superfamily
ETA18_03045	COG0596	Alpha beta hydrolase
ETA18_03050	COG1811	Na channel or pump
ETA18_03055	COG4978	Transcriptional regulator
ETA18_03055	COG0789	Transcriptional regulator
ETA18_03060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETA18_03065	COG0778	Nitroreductase
ETA18_03070	COG0346	lactoylglutathione lyase activity
ETA18_03075	COG2259	Doxx family
ETA18_03080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA18_03095	COG2323	membrane
ETA18_03105	COG0071	Belongs to the small heat shock protein (HSP20) family
ETA18_03120	COG1309	transcriptional regulator
ETA18_03130	COG0456	acetyltransferase
ETA18_03140	COG0673	inositol 2-dehydrogenase activity
ETA18_03145	COG1609	Transcriptional regulator
ETA18_03150	COG2814	Major facilitator Superfamily
ETA18_03165	COG1113	amino acid transport
ETA18_03170	COG2318	DinB family
ETA18_03175	COG1846	Transcriptional regulator
ETA18_03180	COG1033	growth of symbiont in host cell
ETA18_03180	COG2409	Drug exporters of the RND superfamily
ETA18_03185	COG0778	Nitroreductase
ETA18_03190	COG1846	Transcriptional regulator
ETA18_03195	COG2814	Major facilitator Superfamily
ETA18_03200	COG0730	response to heat
ETA18_03205	COG1802	Transcriptional regulator
ETA18_03210	COG3858	chitin binding
ETA18_03210	COG1388	LysM domain
ETA18_03215	COG1819	glycosyl
ETA18_03225	COG1785	Belongs to the alkaline phosphatase family
ETA18_03230	COG5646	InterPro IPR014922
ETA18_03240	COG0454	-acetyltransferase
ETA18_03245	COG1078	dGTPase activity
ETA18_03250	COG1388	LysM domain
ETA18_03255	COG2814	Major facilitator Superfamily
ETA18_03260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA18_03265	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETA18_03270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA18_03275	COG2723	6-phospho-beta-galactosidase activity
ETA18_03280	COG2188	Transcriptional regulator
ETA18_03285	COG1940	carbohydrate kinase activity
ETA18_03290	COG1482	cell wall glycoprotein biosynthetic process
ETA18_03295	COG4124	Belongs to the glycosyl hydrolase 26 family
ETA18_03340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ETA18_03345	COG0802	atpase or kinase
ETA18_03350	COG1214	PFAM Peptidase M22, glycoprotease
ETA18_03355	COG0456	acetyltransferase
ETA18_03360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ETA18_03365	COG0488	(ABC) transporter
ETA18_03370	COG0315	cyclic pyranopterin monophosphate synthase activity
ETA18_03375	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ETA18_03380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETA18_03385	COG0805	protein transport
ETA18_03395	COG1266	CAAX protease self-immunity
ETA18_03400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETA18_03405	COG0459	protein refolding
ETA18_03410	COG1073	alpha beta
ETA18_03415	COG0457	Tetratricopeptide repeat
ETA18_03420	COG1063	alcohol dehydrogenase
ETA18_03425	COG2211	Major facilitator Superfamily
ETA18_03430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETA18_03435	COG1842	Phage shock protein A
ETA18_03440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETA18_03445	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ETA18_03450	COG4260	virion core protein, lumpy skin disease virus
ETA18_03460	COG2814	Major facilitator Superfamily
ETA18_03465	COG1063	alcohol dehydrogenase
ETA18_03470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ETA18_03475	COG0823	Involved in the tonB-independent uptake of proteins
ETA18_03490	COG2267	carboxylic ester hydrolase activity
ETA18_03500	COG2132	Multicopper oxidase
ETA18_03505	COG1113	amino acid transport
ETA18_03515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETA18_03520	COG0714	Associated with various cellular activities
ETA18_03525	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ETA18_03530	COG1305	Transglutaminase-like
ETA18_03535	COG0519	Catalyzes the synthesis of GMP from XMP
ETA18_03535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ETA18_03550	COG2252	PERMEase
ETA18_03555	COG3064	Membrane
ETA18_03565	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ETA18_03575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ETA18_03580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ETA18_03585	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ETA18_03590	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ETA18_03595	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETA18_03600	COG0047	phosphoribosylformylglycinamidine synthase activity
ETA18_03605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETA18_03610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ETA18_03615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ETA18_03620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETA18_03625	COG0138	bifunctional purine biosynthesis protein purh
ETA18_03630	COG0151	Belongs to the GarS family
ETA18_03635	COG1522	sequence-specific DNA binding
ETA18_03640	COG0531	amino acid
ETA18_03650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETA18_03655	COG1470	cell adhesion involved in biofilm formation
ETA18_03660	COG4496	protein, YerC YecD
ETA18_03665	COG0069	glutamate synthase activity
ETA18_03670	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ETA18_03675	COG0210	DNA helicase
ETA18_03680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETA18_03685	COG4851	CamS sex pheromone cAM373 precursor
ETA18_03690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETA18_03695	COG1285	pathogenesis
ETA18_03700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETA18_03705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETA18_03710	COG0154	amidase activity
ETA18_03715	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETA18_03720	COG1309	transcriptional regulator
ETA18_03725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETA18_03730	COG1597	lipid kinase activity
ETA18_03740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETA18_03745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETA18_03765	COG0457	Tetratricopeptide repeat
ETA18_03785	COG5444	nuclease activity
ETA18_03795	COG3586	endonuclease activity
ETA18_03810	COG0457	Tetratricopeptide repeat
ETA18_03820	COG0217	transcriptional regulatory protein
ETA18_03830	COG1309	transcriptional regulator
ETA18_03835	COG3631	Ketosteroid isomerase-related protein
ETA18_03840	COG0702	epimerase
ETA18_03855	COG3546	catalase activity
ETA18_03860	COG0454	-acetyltransferase
ETA18_03870	COG5578	integral membrane protein
ETA18_03875	COG2972	Histidine kinase
ETA18_03880	COG2207	Transcriptional regulator
ETA18_03880	COG4753	response regulator
ETA18_03885	COG1653	transport
ETA18_03890	COG1175	transmembrane transport
ETA18_03895	COG0395	ABC-type sugar transport system, permease component
ETA18_03900	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETA18_03905	COG2207	Transcriptional regulator
ETA18_03910	COG2755	lipolytic protein G-D-S-L family
ETA18_03920	COG5578	integral membrane protein
ETA18_03925	COG3401	FG-GAP repeat protein
ETA18_03930	COG3401	FG-GAP repeat protein
ETA18_03935	COG2755	lipolytic protein G-D-S-L family
ETA18_03940	COG1874	Beta-galactosidase
ETA18_03950	COG1653	transport
ETA18_03955	COG4209	transmembrane transport
ETA18_03960	COG0395	ABC-type sugar transport system, permease component
ETA18_03965	COG1486	melibiose metabolic process
ETA18_03970	COG2323	membrane
ETA18_03975	COG2329	Antibiotic biosynthesis monooxygenase
ETA18_03980	COG0346	lactoylglutathione lyase activity
ETA18_03995	COG5583	Uncharacterized small protein (DUF2292)
ETA18_04000	COG0670	Belongs to the BI1 family
ETA18_04005	COG0697	spore germination
ETA18_04010	COG1846	Transcriptional regulator
ETA18_04015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETA18_04025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETA18_04025	COG2124	cytochrome p450
ETA18_04030	COG1368	sulfuric ester hydrolase activity
ETA18_04035	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ETA18_04040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETA18_04045	COG1442	glycosyl transferase family 8
ETA18_04050	COG1216	Glycosyl transferase, family 2
ETA18_04055	COG1442	glycosyl transferase family 8
ETA18_04060	COG2223	nitrite transmembrane transporter activity
ETA18_04065	COG1011	Hydrolase
ETA18_04070	COG0531	amino acid
ETA18_04075	COG1012	belongs to the aldehyde dehydrogenase family
ETA18_04080	COG0840	transmembrane signaling receptor activity
ETA18_04085	COG0488	(ABC) transporter
ETA18_04095	COG0789	Transcriptional regulator
ETA18_04100	COG2814	Major facilitator Superfamily
ETA18_04110	COG0488	(ABC) transporter
ETA18_04115	COG0513	Belongs to the DEAD box helicase family
ETA18_04120	COG0456	acetyltransferase
ETA18_04125	COG2130	NADP-dependent
ETA18_04130	COG1120	ATPase activity
ETA18_04135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA18_04140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA18_04145	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ETA18_04160	COG3866	Pectate lyase
ETA18_04165	COG0471	metal ion transport
ETA18_04170	COG3290	protein histidine kinase activity
ETA18_04175	COG4565	transcriptional regulatory protein
ETA18_04180	COG3181	Tripartite tricarboxylate transporter family receptor
ETA18_04185	COG2851	Citrate transporter
ETA18_04190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA18_04195	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ETA18_04200	COG1254	Belongs to the acylphosphatase family
ETA18_04205	COG2258	MOSC domain
ETA18_04225	COG0024	Methionine aminopeptidase
ETA18_04230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_04230	COG1263	PTS System
ETA18_04235	COG1368	sulfuric ester hydrolase activity
ETA18_04250	COG1115	amino acid carrier protein
ETA18_04255	COG0531	amino acid
ETA18_04270	COG0697	spore germination
ETA18_04275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_04275	COG1263	PTS System
ETA18_04280	COG0366	Alpha amylase catalytic
ETA18_04285	COG2188	Transcriptional regulator
ETA18_04290	COG0778	Nitroreductase
ETA18_04295	COG0737	Belongs to the 5'-nucleotidase family
ETA18_04300	COG0693	protein deglycase activity
ETA18_04305	COG2814	Major facilitator Superfamily
ETA18_04310	COG4840	Belongs to the UPF0435 family
ETA18_04315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETA18_04320	COG4980	gas vesicle protein
ETA18_04325	COG1295	ribonuclease BN
ETA18_04330	COG0477	Major facilitator Superfamily
ETA18_04335	COG0387	Pfam Sodium calcium exchanger
ETA18_04345	COG0668	transmembrane transport
ETA18_04350	COG0535	radical SAM domain protein
ETA18_04360	COG0726	polysaccharide deacetylase
ETA18_04365	COG2084	Dehydrogenase
ETA18_04370	COG0598	Magnesium transport protein CorA
ETA18_04375	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ETA18_04380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETA18_04390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETA18_04395	COG4637	Psort location Cytoplasmic, score
ETA18_04405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETA18_04410	COG0022	dehydrogenase e1 component
ETA18_04415	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETA18_04420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETA18_04425	COG3284	Transcriptional regulator
ETA18_04435	COG1742	UPF0060 membrane protein
ETA18_04460	COG4842	Belongs to the WXG100 family
ETA18_04475	COG5444	nuclease activity
ETA18_04490	COG1486	melibiose metabolic process
ETA18_04495	COG1737	Transcriptional regulator
ETA18_04500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_04500	COG1263	PTS System
ETA18_04505	COG5434	Belongs to the glycosyl hydrolase 28 family
ETA18_04510	COG1132	(ABC) transporter
ETA18_04515	COG1132	(ABC) transporter
ETA18_04520	COG2259	Doxx family
ETA18_04525	COG2514	catechol 2,3-dioxygenase activity
ETA18_04530	COG4977	sequence-specific DNA binding
ETA18_04530	COG1917	Cupin 2, conserved barrel domain protein
ETA18_04535	COG2814	Major facilitator Superfamily
ETA18_04540	COG1082	Xylose isomerase domain protein TIM barrel
ETA18_04545	COG0673	inositol 2-dehydrogenase activity
ETA18_04550	COG4585	Histidine kinase
ETA18_04555	COG2197	response regulator
ETA18_04560	COG1131	(ABC) transporter
ETA18_04565	COG1511	domain protein
ETA18_04565	COG0842	Transport permease protein
ETA18_04570	COG0842	Transport permease protein
ETA18_04575	COG1695	Transcriptional regulator
ETA18_04580	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ETA18_04585	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ETA18_04590	COG1309	transcriptional regulator
ETA18_04595	COG2814	Major facilitator Superfamily
ETA18_04600	COG2318	DinB family
ETA18_04605	COG2814	Major facilitator Superfamily
ETA18_04610	COG1846	Transcriptional regulator
ETA18_04615	COG0392	lysyltransferase activity
ETA18_04615	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ETA18_04620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA18_04625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA18_04630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA18_04635	COG0384	phenazine biosynthesis protein PhzF
ETA18_04640	COG0778	Nitroreductase
ETA18_04655	COG1090	epimerase
ETA18_04660	COG2137	regulation of response to DNA damage stimulus
ETA18_04670	COG2814	Major facilitator Superfamily
ETA18_04685	COG3103	Sh3 type 3 domain protein
ETA18_04690	COG5658	integral membrane protein
ETA18_04695	COG0596	Alpha beta hydrolase
ETA18_04700	COG0463	Glycosyl transferase, family 2
ETA18_04705	COG4485	Bacterial membrane protein, YfhO
ETA18_04710	COG1988	membrane-bound metal-dependent
ETA18_04715	COG1194	a g-specific adenine glycosylase
ETA18_04725	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_04740	COG3557	Belongs to the UPF0374 family
ETA18_04745	COG1132	(ABC) transporter
ETA18_04750	COG4129	membrane
ETA18_04755	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETA18_04760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETA18_04765	COG0735	belongs to the Fur family
ETA18_04875	COG4326	sporulation control protein
ETA18_04885	COG5577	PFAM Coat F domain
ETA18_04890	COG3340	Belongs to the peptidase S51 family
ETA18_04895	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ETA18_04900	COG0277	FAD linked oxidase domain protein
ETA18_04910	COG0753	catalase activity
ETA18_04915	COG1116	anion transmembrane transporter activity
ETA18_04920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETA18_04925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETA18_04930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETA18_04940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ETA18_04950	COG1476	TRANSCRIPTIONal
ETA18_04960	COG3382	B3 4 domain protein
ETA18_04965	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ETA18_04975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ETA18_04980	COG0789	Transcriptional regulator
ETA18_04985	COG1664	Polymer-forming cytoskeletal
ETA18_04990	COG1664	Polymer-forming cytoskeletal
ETA18_04995	COG2766	serine protein kinase
ETA18_05000	COG2718	Belongs to the UPF0229 family
ETA18_05005	COG1846	Transcriptional regulator
ETA18_05010	COG1566	PFAM secretion protein HlyD family protein
ETA18_05015	COG2814	Major facilitator Superfamily
ETA18_05020	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETA18_05040	COG1725	Transcriptional regulator
ETA18_05045	COG1131	(ABC) transporter
ETA18_05050	COG1131	(ABC) transporter
ETA18_05055	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETA18_05060	COG1278	Cold shock
ETA18_05070	COG1464	Belongs to the NlpA lipoprotein family
ETA18_05075	COG3706	GGDEF domain
ETA18_05080	COG1823	symporter activity
ETA18_05100	COG5577	PFAM Coat F domain
ETA18_05105	COG1525	nuclease
ETA18_05105	COG0737	Belongs to the 5'-nucleotidase family
ETA18_05105	COG4085	toxin activity
ETA18_05110	COG3764	Sortase (surface protein transpeptidase)
ETA18_05115	COG0564	pseudouridine synthase activity
ETA18_05125	COG0517	IMP dehydrogenase activity
ETA18_05130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETA18_05135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETA18_05135	COG3153	acetyltransferase
ETA18_05140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETA18_05145	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ETA18_05150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETA18_05155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ETA18_05160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ETA18_05165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETA18_05170	COG4585	Histidine kinase
ETA18_05170	COG2203	Gaf domain
ETA18_05175	COG2197	response regulator
ETA18_05180	COG0431	NADPH-dependent FMN reductase
ETA18_05195	COG1388	LysM domain
ETA18_05195	COG0791	NLP P60 protein
ETA18_05200	COG1959	2 iron, 2 sulfur cluster binding
ETA18_05205	COG0668	transmembrane transport
ETA18_05210	COG2719	SpoVR family
ETA18_05215	COG1785	Belongs to the alkaline phosphatase family
ETA18_05220	COG0791	NLP P60 protein
ETA18_05220	COG1388	LysM domain
ETA18_05225	COG0583	DNA-binding transcription factor activity
ETA18_05230	COG0372	Belongs to the citrate synthase family
ETA18_05235	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_05240	COG0531	amino acid
ETA18_05245	COG0733	neurotransmitter:sodium symporter activity
ETA18_05250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA18_05255	COG0456	acetyltransferase
ETA18_05270	COG1595	DNA-templated transcription, initiation
ETA18_05275	COG0667	Aldo Keto reductase
ETA18_05280	COG0204	Acyl-transferase
ETA18_05285	COG1253	flavin adenine dinucleotide binding
ETA18_05290	COG0789	Transcriptional regulator
ETA18_05295	COG0436	Aminotransferase
ETA18_05300	COG1253	flavin adenine dinucleotide binding
ETA18_05305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETA18_05310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETA18_05315	COG0584	glycerophosphoryl diester phosphodiesterase
ETA18_05325	COG0668	transmembrane transport
ETA18_05330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ETA18_05335	COG0726	polysaccharide deacetylase
ETA18_05340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETA18_05345	COG1757	Na H antiporter
ETA18_05350	COG0589	response to stress
ETA18_05360	COG1132	(ABC) transporter
ETA18_05365	COG1132	(ABC) transporter
ETA18_05370	COG0702	epimerase
ETA18_05390	COG0189	ligase activity
ETA18_05395	COG0189	ligase activity
ETA18_05400	COG4399	Belongs to the UPF0754 family
ETA18_05405	COG3679	Belongs to the UPF0342 family
ETA18_05410	COG4335	DNA alkylation repair
ETA18_05415	COG0561	phosphatase activity
ETA18_05420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETA18_05425	COG0475	glutathione-regulated potassium exporter activity
ETA18_05430	COG0490	domain, Protein
ETA18_05440	COG1024	Enoyl-CoA hydratase
ETA18_05450	COG4152	abc transporter atp-binding protein
ETA18_05455	COG1668	transmembrane transport
ETA18_05460	COG0420	3'-5' exonuclease activity
ETA18_05465	COG4717	serine-type aminopeptidase activity
ETA18_05470	COG3481	metal-dependent phosphohydrolase, HD sub domain
ETA18_05480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETA18_05510	COG1846	Transcriptional regulator
ETA18_05515	COG4980	gas vesicle protein
ETA18_05530	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ETA18_05535	COG0537	adenosine 5'-monophosphoramidase activity
ETA18_05540	COG1131	(ABC) transporter
ETA18_05545	COG4473	ABC transporter
ETA18_05555	COG1473	amidohydrolase
ETA18_05560	COG3069	C4-dicarboxylate transmembrane transporter activity
ETA18_05570	COG2329	Antibiotic biosynthesis monooxygenase
ETA18_05575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETA18_05580	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ETA18_05595	COG1309	transcriptional regulator
ETA18_05600	COG1511	domain protein
ETA18_05605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETA18_05610	COG4377	Putative membrane peptidase family (DUF2324)
ETA18_05620	COG1363	Peptidase, m42
ETA18_05625	COG4405	Protein conserved in bacteria
ETA18_05630	COG1301	dicarboxylic acid transport
ETA18_05640	COG1234	tRNA 3'-trailer cleavage
ETA18_05645	COG0095	Lipoate-protein ligase
ETA18_05650	COG0702	epimerase
ETA18_05655	COG0318	PFAM AMP-dependent synthetase and ligase
ETA18_05665	COG0501	Belongs to the peptidase M48B family
ETA18_05670	COG1404	Belongs to the peptidase S8 family
ETA18_05675	COG0456	acetyltransferase
ETA18_05685	COG0604	alcohol dehydrogenase
ETA18_05690	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ETA18_05695	COG0406	alpha-ribazole phosphatase activity
ETA18_05700	COG0183	Belongs to the thiolase family
ETA18_05705	COG0318	PFAM AMP-dependent synthetase and ligase
ETA18_05710	COG1268	BioY protein
ETA18_05715	COG0840	transmembrane signaling receptor activity
ETA18_05720	COG0723	plastoquinol--plastocyanin reductase activity
ETA18_05720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETA18_05725	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_05735	COG4903	ComK protein
ETA18_05740	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_05750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETA18_05765	COG0398	Pfam SNARE associated Golgi protein
ETA18_05770	COG0681	Belongs to the peptidase S26 family
ETA18_05775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETA18_05780	COG1846	Transcriptional regulator
ETA18_05785	COG0738	Major facilitator superfamily
ETA18_05790	COG0673	inositol 2-dehydrogenase activity
ETA18_05795	COG0561	phosphatase activity
ETA18_05800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETA18_05805	COG1609	Transcriptional regulator
ETA18_05810	COG3180	Ammonia monooxygenase
ETA18_05815	COG2814	Major facilitator Superfamily
ETA18_05815	COG0477	Major facilitator Superfamily
ETA18_05820	COG4533	DNA binding
ETA18_05830	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ETA18_05835	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ETA18_05840	COG1074	ATP-dependent DNA helicase activity
ETA18_05845	COG0420	3'-5' exonuclease activity
ETA18_05850	COG0419	ATPase involved in DNA repair
ETA18_05855	COG1403	HNH endonuclease
ETA18_05895	COG5337	Spore coat protein CotH
ETA18_05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETA18_05910	COG1404	Belongs to the peptidase S8 family
ETA18_05920	COG0367	asparagine synthase
ETA18_05925	COG2318	DinB family
ETA18_05930	COG1562	ergosterol biosynthetic process
ETA18_05935	COG0534	Mate efflux family protein
ETA18_05940	COG1917	Cupin 2, conserved barrel domain protein
ETA18_05940	COG2207	Transcriptional regulator
ETA18_05945	COG1609	Transcriptional regulator
ETA18_05950	COG0673	inositol 2-dehydrogenase activity
ETA18_05955	COG2318	DinB family
ETA18_05960	COG1279	arginine transmembrane transporter activity
ETA18_05965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA18_05970	COG1357	PFAM Pentapeptide repeats (8 copies)
ETA18_05975	COG2267	carboxylic ester hydrolase activity
ETA18_05980	COG0529	Catalyzes the synthesis of activated sulfate
ETA18_05985	COG2046	Belongs to the sulfate adenylyltransferase family
ETA18_05990	COG0175	sulfate reduction
ETA18_05995	COG2045	Belongs to the ComB family
ETA18_06000	COG1809	phosphosulfolactate synthase activity
ETA18_06005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA18_06010	COG4948	Mandelate Racemase Muconate Lactonizing
ETA18_06015	COG2814	Major facilitator Superfamily
ETA18_06020	COG0454	-acetyltransferase
ETA18_06025	COG2153	protein acetylation
ETA18_06030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ETA18_06030	COG0646	methionine synthase
ETA18_06035	COG1666	GTP binding
ETA18_06040	COG2996	Protein conserved in bacteria
ETA18_06060	COG1695	Transcriptional regulator
ETA18_06075	COG3227	Zinc metalloprotease (Elastase)
ETA18_06080	COG1307	EDD domain protein, DegV family
ETA18_06085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA18_06100	COG0561	phosphatase activity
ETA18_06105	COG1073	alpha beta
ETA18_06110	COG2151	metal-sulfur cluster biosynthetic enzyme
ETA18_06120	COG0277	FAD linked oxidase domain protein
ETA18_06125	COG2271	Major facilitator Superfamily
ETA18_06130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ETA18_06145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETA18_06150	COG0505	Belongs to the CarA family
ETA18_06155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETA18_06160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ETA18_06175	COG2267	carboxylic ester hydrolase activity
ETA18_06185	COG1744	ABC transporter substrate-binding protein PnrA-like
ETA18_06200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETA18_06205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETA18_06210	COG5504	Zn-dependent protease
ETA18_06215	COG0444	Belongs to the ABC transporter superfamily
ETA18_06220	COG4608	Belongs to the ABC transporter superfamily
ETA18_06230	COG0601	transmembrane transport
ETA18_06235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETA18_06245	COG0180	Tryptophanyl-tRNA synthetase
ETA18_06250	COG4166	transmembrane transport
ETA18_06255	COG0601	transmembrane transport
ETA18_06260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETA18_06265	COG0444	Belongs to the ABC transporter superfamily
ETA18_06270	COG4608	Belongs to the ABC transporter superfamily
ETA18_06280	COG0456	acetyltransferase
ETA18_06285	COG1393	Belongs to the ArsC family
ETA18_06290	COG0861	Integral membrane protein TerC family
ETA18_06300	COG4862	establishment of competence for transformation
ETA18_06310	COG4469	Competence protein
ETA18_06315	COG1164	Oligoendopeptidase f
ETA18_06335	COG2346	COG2346, Truncated hemoglobins
ETA18_06340	COG0741	lytic transglycosylase activity
ETA18_06345	COG4116	CYTH
ETA18_06355	COG2357	RelA SpoT domain protein
ETA18_06360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETA18_06365	COG0564	pseudouridine synthase activity
ETA18_06370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ETA18_06375	COG0475	glutathione-regulated potassium exporter activity
ETA18_06375	COG0569	domain protein
ETA18_06380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ETA18_06385	COG0352	thiamine-phosphate diphosphorylase activity
ETA18_06390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETA18_06395	COG2104	thiamine diphosphate biosynthetic process
ETA18_06400	COG2022	thiamine diphosphate biosynthetic process
ETA18_06405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETA18_06410	COG0351	phosphomethylpyrimidine kinase
ETA18_06415	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ETA18_06480	COG2153	protein acetylation
ETA18_06485	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETA18_06490	COG2382	esterase
ETA18_06495	COG0626	cystathionine gamma-synthase activity
ETA18_06500	COG0626	cystathionine gamma-synthase activity
ETA18_06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA18_06510	COG5505	Protein of unknown function (DUF819)
ETA18_06530	COG5444	nuclease activity
ETA18_06580	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETA18_06585	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_06595	COG3711	transcriptional antiterminator
ETA18_06595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA18_06605	COG1482	cell wall glycoprotein biosynthetic process
ETA18_06615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA18_06625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ETA18_06645	COG0109	protoheme IX farnesyltransferase activity
ETA18_06655	COG0726	polysaccharide deacetylase
ETA18_06670	COG5504	Zn-dependent protease
ETA18_06675	COG2205	protein histidine kinase activity
ETA18_06685	COG3383	formate dehydrogenase (NAD+) activity
ETA18_06690	COG2427	Protein of unknown function (DUF1641)
ETA18_06700	COG1051	belongs to the nudix hydrolase family
ETA18_06710	COG2124	cytochrome p450
ETA18_06715	COG1819	glycosyl
ETA18_06725	COG1587	Uroporphyrinogen-III synthase
ETA18_06730	COG0390	transport system, permease component
ETA18_06735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETA18_06740	COG0697	spore germination
ETA18_06745	COG4297	protein containing double-stranded beta helix domain
ETA18_06755	COG1252	NADH dehydrogenase
ETA18_06760	COG1904	glucuronate isomerase
ETA18_06765	COG2211	Major facilitator Superfamily
ETA18_06770	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ETA18_06775	COG1063	alcohol dehydrogenase
ETA18_06780	COG1312	Catalyzes the dehydration of D-mannonate
ETA18_06785	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_06790	COG2271	Major facilitator Superfamily
ETA18_06795	COG1609	Transcriptional regulator
ETA18_06800	COG0246	Mannitol dehydrogenase
ETA18_06805	COG2721	sulfolactate sulfo-lyase activity
ETA18_06810	COG0730	response to heat
ETA18_06815	COG2318	DinB family
ETA18_06820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETA18_06825	COG0457	Tetratricopeptide repeat
ETA18_06835	COG2350	Protein conserved in bacteria
ETA18_06840	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETA18_06840	COG1388	LysM domain
ETA18_06840	COG3409	Peptidoglycan-binding domain 1 protein
ETA18_06850	COG4195	phage-related replication protein
ETA18_06855	COG3546	catalase activity
ETA18_06860	COG2856	Zn peptidase
ETA18_06865	COG1396	sequence-specific DNA binding
ETA18_06875	COG1522	sequence-specific DNA binding
ETA18_06880	COG1484	DNA-dependent DNA replication
ETA18_06900	COG1595	DNA-templated transcription, initiation
ETA18_06905	COG3728	DNA packaging
ETA18_06905	COG5484	DNA packaging
ETA18_06910	COG1783	phage Terminase large subunit
ETA18_06915	COG5518	Phage portal protein
ETA18_06920	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ETA18_06925	COG4653	Phage capsid family
ETA18_06975	COG3953	SLT domain
ETA18_06975	COG5412	phage tail tape measure protein
ETA18_06980	COG1652	LysM domain
ETA18_06985	COG4193	domain, Protein
ETA18_06995	COG3628	GPW Gp25 family protein
ETA18_07000	COG3299	homolog of phage Mu protein gp47
ETA18_07005	COG3778	Protein conserved in bacteria
ETA18_07045	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETA18_07045	COG3409	Peptidoglycan-binding domain 1 protein
ETA18_07065	COG0306	phosphate transporter
ETA18_07070	COG1392	Phosphate transport regulator
ETA18_07075	COG0531	amino acid
ETA18_07080	COG0346	lactoylglutathione lyase activity
ETA18_07085	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETA18_07090	COG0463	Glycosyl transferase, family 2
ETA18_07100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETA18_07105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETA18_07110	COG2362	D-Aminopeptidase
ETA18_07115	COG0601	transmembrane transport
ETA18_07120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETA18_07125	COG0444	Belongs to the ABC transporter superfamily
ETA18_07130	COG4166	transmembrane transport
ETA18_07135	COG1619	proteins homologs of microcin C7 resistance protein MccF
ETA18_07140	COG4948	Mandelate Racemase Muconate Lactonizing
ETA18_07145	COG0791	NLP P60 protein
ETA18_07150	COG4608	Belongs to the ABC transporter superfamily
ETA18_07155	COG2706	6-phosphogluconolactonase activity
ETA18_07160	COG1834	amidinotransferase
ETA18_07165	COG1607	acyl-coa hydrolase
ETA18_07170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ETA18_07170	COG1017	nitric oxide dioxygenase activity
ETA18_07180	COG2323	membrane
ETA18_07185	COG2318	DinB family
ETA18_07190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA18_07195	COG2076	Multidrug Resistance protein
ETA18_07200	COG2076	Multidrug Resistance protein
ETA18_07205	COG0788	formyltetrahydrofolate deformylase activity
ETA18_07210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETA18_07215	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ETA18_07220	COG1764	response to oxidative stress
ETA18_07225	COG1846	Transcriptional regulator
ETA18_07230	COG1764	response to oxidative stress
ETA18_07240	COG0590	tRNA wobble adenosine to inosine editing
ETA18_07250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETA18_07255	COG1404	Belongs to the peptidase S8 family
ETA18_07260	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA18_07265	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETA18_07270	COG1122	ATPase activity
ETA18_07275	COG4721	ABC-type cobalt transport system, permease component
ETA18_07285	COG0745	RESPONSE REGULATOR receiver
ETA18_07290	COG5002	protein histidine kinase activity
ETA18_07290	COG3850	Histidine kinase
ETA18_07295	COG3212	peptidase
ETA18_07300	COG3212	peptidase
ETA18_07315	COG2239	Acts as a magnesium transporter
ETA18_07320	COG0789	Transcriptional regulator
ETA18_07335	COG1846	Transcriptional regulator
ETA18_07340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETA18_07345	COG0726	polysaccharide deacetylase
ETA18_07350	COG1408	metallophosphoesterase
ETA18_07360	COG0463	Glycosyl transferase, family 2
ETA18_07365	COG1793	dna ligase
ETA18_07365	COG3285	dna ligase
ETA18_07370	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ETA18_07375	COG5001	Diguanylate cyclase
ETA18_07375	COG3300	MHYT domain
ETA18_07380	COG0586	Pfam SNARE associated Golgi protein
ETA18_07385	COG0861	Integral membrane protein TerC family
ETA18_07390	COG1191	sigma factor activity
ETA18_07410	COG0501	Belongs to the peptidase M48B family
ETA18_07415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETA18_07430	COG3594	Acyltransferase
ETA18_07435	COG5002	protein histidine kinase activity
ETA18_07440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETA18_07450	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ETA18_07455	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ETA18_07460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETA18_07465	COG0436	Aminotransferase
ETA18_07470	COG1850	ribulose-bisphosphate carboxylase activity
ETA18_07475	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ETA18_07480	COG0235	Class ii aldolase
ETA18_07485	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ETA18_07490	COG3339	Conserved Protein
ETA18_07505	COG3852	Histidine kinase
ETA18_07515	COG1846	Transcriptional regulator
ETA18_07520	COG1360	Flagellar Motor Protein
ETA18_07525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ETA18_07535	COG0542	response to heat
ETA18_07540	COG3949	Membrane
ETA18_07545	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ETA18_07550	COG0720	synthase
ETA18_07555	COG0602	queuosine metabolic process
ETA18_07560	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ETA18_07565	COG1733	regulation of RNA biosynthetic process
ETA18_07570	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_07575	COG1388	LysM domain
ETA18_07575	COG4641	Protein conserved in bacteria
ETA18_07580	COG1388	LysM domain
ETA18_07585	COG3858	chitin binding
ETA18_07595	COG4873	Protein conserved in bacteria
ETA18_07605	COG3773	Cell wall hydrolase
ETA18_07610	COG2244	polysaccharide biosynthetic process
ETA18_07615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA18_07620	COG2217	Heavy metal translocating P-type atpase
ETA18_07630	COG0006	proline dipeptidase activity
ETA18_07635	COG1609	Transcriptional regulator
ETA18_07640	COG3711	transcriptional antiterminator
ETA18_07645	COG1263	PTS System
ETA18_07645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_07645	COG2190	(PTS) system
ETA18_07650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA18_07655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETA18_07665	COG1533	DNA photolyase activity
ETA18_07670	COG0456	acetyltransferase
ETA18_07675	COG0840	transmembrane signaling receptor activity
ETA18_07680	COG2084	Dehydrogenase
ETA18_07685	COG2340	Cysteine-rich secretory protein family
ETA18_07690	COG0768	penicillin binding
ETA18_07695	COG4191	Histidine kinase
ETA18_07700	COG0436	Aminotransferase
ETA18_07710	COG0835	chemotaxis
ETA18_07710	COG0784	Response regulator, receiver
ETA18_07720	COG2814	Major facilitator Superfamily
ETA18_07725	COG1376	ErfK ybiS ycfS ynhG family protein
ETA18_07730	COG1408	metallophosphoesterase
ETA18_07735	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_07740	COG2200	EAL domain
ETA18_07745	COG4703	Protein of unknown function (DUF1797)
ETA18_07750	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ETA18_07760	COG0517	IMP dehydrogenase activity
ETA18_07765	COG0583	DNA-binding transcription factor activity
ETA18_07770	COG0716	FMN binding
ETA18_07780	COG0716	FMN binding
ETA18_07785	COG2171	N-acyltransferase activity
ETA18_07790	COG1473	amidohydrolase
ETA18_07800	COG0668	transmembrane transport
ETA18_07805	COG0450	alkyl hydroperoxide reductase
ETA18_07810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA18_07825	COG0746	molybdenum cofactor guanylyltransferase activity
ETA18_07830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETA18_07835	COG0303	'Molybdopterin
ETA18_07840	COG1763	Mo-molybdopterin cofactor biosynthetic process
ETA18_07845	COG0314	molybdopterin synthase activity
ETA18_07850	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ETA18_07855	COG1132	(ABC) transporter
ETA18_07860	COG1132	(ABC) transporter
ETA18_07870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETA18_07875	COG1136	(ABC) transporter
ETA18_07880	COG0577	efflux transmembrane transporter activity
ETA18_07885	COG1349	DNA-binding transcription factor activity
ETA18_07890	COG1105	Belongs to the carbohydrate kinase PfkB family
ETA18_07895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETA18_07895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA18_07895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETA18_07900	COG0681	Belongs to the peptidase S26 family
ETA18_07910	COG0488	(ABC) transporter
ETA18_07915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ETA18_07920	COG2309	aminopeptidase activity
ETA18_07930	COG1077	Cell shape determining protein MreB Mrl
ETA18_07935	COG2002	toxin-antitoxin pair type II binding
ETA18_07940	COG3852	Histidine kinase
ETA18_07945	COG2105	PFAM AIG2 family protein
ETA18_07945	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ETA18_07950	COG0569	domain protein
ETA18_07955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETA18_07960	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ETA18_07970	COG0561	phosphatase activity
ETA18_07975	COG0242	peptide deformylase activity
ETA18_07985	COG0497	DNA recombination
ETA18_07990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETA18_07995	COG0022	dehydrogenase e1 component
ETA18_08000	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETA18_08005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETA18_08010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA18_08020	COG1982	Orn Lys Arg decarboxylase major
ETA18_08025	COG4476	Belongs to the UPF0223 family
ETA18_08030	COG4493	Belongs to the UPF0637 family
ETA18_08040	COG0483	inositol monophosphate 1-phosphatase activity
ETA18_08050	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ETA18_08070	COG1595	DNA-templated transcription, initiation
ETA18_08100	COG4896	Protein conserved in bacteria
ETA18_08110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ETA18_08115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETA18_08120	COG2066	Belongs to the glutaminase family
ETA18_08125	COG4838	Belongs to the UPF0358 family
ETA18_08130	COG0772	Belongs to the SEDS family
ETA18_08135	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ETA18_08140	COG1612	heme a metabolic process
ETA18_08145	COG0109	protoheme IX farnesyltransferase activity
ETA18_08150	COG2010	Cytochrome c
ETA18_08150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETA18_08155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETA18_08160	COG1845	cytochrome c oxidase, subunit III
ETA18_08165	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ETA18_08170	COG3336	cytochrome c oxidase
ETA18_08180	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ETA18_08185	COG2340	Cysteine-rich secretory protein family
ETA18_08200	COG3679	Belongs to the UPF0342 family
ETA18_08205	COG4471	UPF0298 protein
ETA18_08210	COG0742	ribosomal rna small subunit methyltransferase
ETA18_08215	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ETA18_08220	COG3314	Sporulation integral membrane protein YlbJ
ETA18_08225	COG1752	Esterase of the alpha-beta hydrolase superfamily
ETA18_08230	COG3480	Lon protease (S16) C-terminal proteolytic domain
ETA18_08235	COG1323	Belongs to the UPF0348 family
ETA18_08245	COG1399	metal-binding, possibly nucleic acid-binding protein
ETA18_08250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ETA18_08260	COG0454	-acetyltransferase
ETA18_08265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ETA18_08270	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ETA18_08275	COG2001	Belongs to the MraZ family
ETA18_08280	COG0275	rRNA processing
ETA18_08285	COG4839	cell division protein FtsL
ETA18_08295	COG0768	penicillin binding
ETA18_08300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ETA18_08305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETA18_08310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ETA18_08315	COG0772	Belongs to the SEDS family
ETA18_08320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETA18_08325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ETA18_08330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ETA18_08335	COG3879	Bacterial protein of unknown function (DUF881)
ETA18_08340	COG3879	Bacterial protein of unknown function (DUF881)
ETA18_08345	COG3856	small basic protein
ETA18_08350	COG0849	cell division
ETA18_08355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ETA18_08360	COG1404	Belongs to the peptidase S8 family
ETA18_08360	COG4412	M6 family metalloprotease domain protein
ETA18_08370	COG1191	sigma factor activity
ETA18_08375	COG1191	sigma factor activity
ETA18_08380	COG1119	ATPase activity
ETA18_08385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETA18_08390	COG1873	PFAM PRC-barrel domain
ETA18_08400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ETA18_08405	COG1799	cell septum assembly
ETA18_08410	COG0762	integral membrane protein
ETA18_08415	COG2302	S4 RNA-binding domain
ETA18_08420	COG3599	regulation of cell shape
ETA18_08425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ETA18_08430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETA18_08435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ETA18_08440	COG0564	pseudouridine synthase activity
ETA18_08445	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ETA18_08450	COG2233	PERMEase
ETA18_08455	COG0540	Belongs to the ATCase OTCase family
ETA18_08460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETA18_08465	COG0505	Belongs to the CarA family
ETA18_08470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETA18_08475	COG0543	2 iron, 2 sulfur cluster binding
ETA18_08480	COG0167	dihydroorotate dehydrogenase activity
ETA18_08485	COG0284	orotidine-5'-phosphate decarboxylase activity
ETA18_08490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ETA18_08495	COG0175	sulfate reduction
ETA18_08500	COG0306	phosphate transporter
ETA18_08505	COG2046	Belongs to the sulfate adenylyltransferase family
ETA18_08510	COG0529	Catalyzes the synthesis of activated sulfate
ETA18_08515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETA18_08520	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
ETA18_08525	COG1648	precorrin-2 dehydrogenase activity
ETA18_08535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETA18_08540	COG1561	YicC-like family, N-terminal region
ETA18_08545	COG2052	Domain of unknown function (DUF370)
ETA18_08550	COG0194	GDP metabolic process
ETA18_08555	COG1758	RNA polymerase activity
ETA18_08560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETA18_08565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETA18_08570	COG0242	peptide deformylase activity
ETA18_08575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ETA18_08580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETA18_08580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETA18_08585	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ETA18_08590	COG0631	protein serine/threonine phosphatase activity
ETA18_08595	COG0515	serine threonine protein kinase
ETA18_08595	COG2815	serine threonine protein kinase
ETA18_08600	COG1162	GTPase activity
ETA18_08605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ETA18_08610	COG1564	THIamine pyrophosphokinase
ETA18_08620	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ETA18_08625	COG1302	Protein conserved in bacteria
ETA18_08630	COG1461	Dihydroxyacetone kinase
ETA18_08635	COG1760	l-serine dehydratase
ETA18_08640	COG1760	l-serine dehydratase
ETA18_08645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETA18_08650	COG1349	DNA-binding transcription factor activity
ETA18_08650	COG2050	protein possibly involved in aromatic compounds catabolism
ETA18_08655	COG0416	fatty acid biosynthetic process
ETA18_08660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETA18_08665	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_08670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETA18_08675	COG0571	ribonuclease III activity
ETA18_08680	COG1196	nuclear chromosome segregation
ETA18_08685	COG0552	protein localization to endoplasmic reticulum
ETA18_08695	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ETA18_08700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETA18_08705	COG0228	four-way junction DNA binding
ETA18_08710	COG1837	Belongs to the UPF0109 family
ETA18_08720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ETA18_08725	COG0336	Belongs to the RNA methyltransferase TrmD family
ETA18_08730	COG0335	large ribosomal subunit rRNA binding
ETA18_08735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETA18_08740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ETA18_08750	COG2257	FlhB HrpN YscU SpaS Family
ETA18_08755	COG0045	succinate-CoA ligase (ADP-forming) activity
ETA18_08760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ETA18_08765	COG0758	DNA mediated transformation
ETA18_08770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETA18_08775	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ETA18_08780	COG4974	Belongs to the 'phage' integrase family
ETA18_08785	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ETA18_08790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ETA18_08795	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ETA18_08800	COG1815	bacterial-type flagellum-dependent cell motility
ETA18_08805	COG1558	bacterial-type flagellum-dependent cell motility
ETA18_08810	COG1677	Flagellar hook-basal body complex protein FliE
ETA18_08815	COG1766	The M ring may be actively involved in energy transduction
ETA18_08820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETA18_08825	COG1317	bacterial-type flagellum organization
ETA18_08830	COG1157	protein secretion by the type III secretion system
ETA18_08835	COG2882	bacterial-type flagellum organization
ETA18_08840	COG3334	PFAM MgtE intracellular
ETA18_08845	COG3144	bacterial-type flagellum assembly
ETA18_08850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ETA18_08855	COG4786	Flagellar basal body rod
ETA18_08860	COG1582	Flagellar protein (FlbD)
ETA18_08865	COG1580	Controls the rotational direction of flagella during chemotaxis
ETA18_08870	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETA18_08875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETA18_08875	COG1776	CheC inhibitor of MCP methylation
ETA18_08880	COG2201	protein-glutamate methylesterase activity
ETA18_08885	COG3190	flagellar
ETA18_08890	COG1338	Plays a role in the flagellum-specific transport system
ETA18_08895	COG1987	bacterial-type flagellum assembly
ETA18_08900	COG1684	flagellar biosynthetic protein fliR
ETA18_08905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETA18_08910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETA18_08915	COG1419	protein localization to endoplasmic reticulum
ETA18_08920	COG0455	bacterial-type flagellum organization
ETA18_08925	COG2201	protein-glutamate methylesterase activity
ETA18_08930	COG0643	Histidine kinase
ETA18_08930	COG2198	Histidine kinase
ETA18_08935	COG0835	chemotaxis
ETA18_08940	COG1776	CheC inhibitor of MCP methylation
ETA18_08945	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ETA18_08950	COG1191	sigma factor activity
ETA18_08960	COG0052	Belongs to the universal ribosomal protein uS2 family
ETA18_08965	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ETA18_08970	COG0528	UMP kinase activity
ETA18_08975	COG0233	cytoplasmic translational termination
ETA18_08980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ETA18_08985	COG4589	Belongs to the CDS family
ETA18_08990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ETA18_08995	COG0750	zinc metalloprotease
ETA18_09000	COG0442	prolyl-tRNA aminoacylation
ETA18_09005	COG2176	DNA-directed DNA polymerase activity
ETA18_09010	COG0779	Required for maturation of 30S ribosomal subunits
ETA18_09015	COG0195	Participates in both transcription termination and antitermination
ETA18_09020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ETA18_09025	COG1358	cellular component organization or biogenesis
ETA18_09030	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ETA18_09035	COG1550	Protein conserved in bacteria
ETA18_09040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ETA18_09045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ETA18_09050	COG0196	riboflavin kinase activity
ETA18_09055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ETA18_09060	COG1185	polyribonucleotide nucleotidyltransferase activity
ETA18_09065	COG0726	polysaccharide deacetylase
ETA18_09070	COG0612	Peptidase, M16
ETA18_09075	COG1873	PFAM PRC-barrel domain
ETA18_09080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETA18_09085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETA18_09090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ETA18_09095	COG0527	aspartate kinase activity
ETA18_09100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETA18_09105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ETA18_09110	COG0740	serine-type endopeptidase activity
ETA18_09120	COG1674	ftsk spoiiie
ETA18_09120	COG4980	gas vesicle protein
ETA18_09125	COG2188	Transcriptional regulator
ETA18_09130	COG2814	Major facilitator Superfamily
ETA18_09135	COG0612	Peptidase, M16
ETA18_09140	COG0612	Peptidase, M16
ETA18_09145	COG0300	oxidoreductase activity
ETA18_09160	COG1426	Protein conserved in bacteria
ETA18_09165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETA18_09170	COG1058	Belongs to the CinA family
ETA18_09170	COG1546	Belongs to the CinA family
ETA18_09175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ETA18_09180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETA18_09185	COG1418	mRNA catabolic process
ETA18_09190	COG1692	metallophosphoesterase
ETA18_09195	COG2359	stage V sporulation protein S
ETA18_09200	COG1063	alcohol dehydrogenase
ETA18_09205	COG0156	8-amino-7-oxononanoate synthase activity
ETA18_09210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETA18_09215	COG4550	Control of competence regulator ComK, YlbF/YmcA
ETA18_09225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ETA18_09230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ETA18_09245	COG3226	Transcriptional regulator
ETA18_09250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA18_09260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETA18_09265	COG3321	synthase
ETA18_09270	COG2070	2-Nitropropane dioxygenase
ETA18_09270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETA18_09275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETA18_09280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETA18_09285	COG3425	synthase
ETA18_09290	COG1024	Enoyl-CoA hydratase
ETA18_09295	COG1024	Enoyl-CoA hydratase
ETA18_09300	COG0300	oxidoreductase activity
ETA18_09300	COG3321	synthase
ETA18_09300	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_09300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_09300	COG0318	PFAM AMP-dependent synthetase and ligase
ETA18_09305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETA18_09305	COG0300	oxidoreductase activity
ETA18_09305	COG3321	synthase
ETA18_09305	COG4221	oxidoreductase activity
ETA18_09310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_09310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETA18_09310	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_09310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETA18_09310	COG3321	synthase
ETA18_09315	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_09315	COG3321	synthase
ETA18_09315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_09315	COG4221	oxidoreductase activity
ETA18_09320	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ETA18_09320	COG3321	synthase
ETA18_09320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETA18_09320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ETA18_09325	COG2124	cytochrome p450
ETA18_09335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA18_09340	COG1404	Belongs to the peptidase S8 family
ETA18_09350	COG4195	phage-related replication protein
ETA18_09355	COG1764	response to oxidative stress
ETA18_09360	COG2076	Multidrug Resistance protein
ETA18_09365	COG2076	Multidrug Resistance protein
ETA18_09380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ETA18_09385	COG1923	regulation of RNA biosynthetic process
ETA18_09400	COG1780	Probably involved in ribonucleotide reductase function
ETA18_09405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETA18_09410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETA18_09415	COG4112	unkown
ETA18_09420	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA18_09430	COG0464	growth
ETA18_09435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETA18_09440	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ETA18_09445	COG0789	Transcriptional regulator
ETA18_09450	COG0174	glutamine synthetase
ETA18_09455	COG4974	Belongs to the 'phage' integrase family
ETA18_09525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA18_09550	COG0135	phosphoribosylanthranilate isomerase activity
ETA18_09555	COG2211	Major facilitator Superfamily
ETA18_09560	COG3507	Belongs to the glycosyl hydrolase 43 family
ETA18_09565	COG1940	carbohydrate kinase activity
ETA18_09570	COG2115	Belongs to the xylose isomerase family
ETA18_09575	COG1070	Carbohydrate kinase
ETA18_09585	COG1525	nuclease
ETA18_09590	COG2814	Major facilitator Superfamily
ETA18_09595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ETA18_09605	COG0756	dUTP diphosphatase activity
ETA18_09620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ETA18_09645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETA18_09655	COG3832	glyoxalase III activity
ETA18_09665	COG0697	spore germination
ETA18_09670	COG0531	amino acid
ETA18_09700	COG4195	phage-related replication protein
ETA18_09710	COG0346	lactoylglutathione lyase activity
ETA18_09720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ETA18_09725	COG1388	LysM domain
ETA18_09730	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETA18_09735	COG4224	UPF0291 protein
ETA18_09740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ETA18_09750	COG3763	UPF0154 protein
ETA18_09760	COG0785	Cytochrome C biogenesis protein
ETA18_09765	COG2201	protein-glutamate methylesterase activity
ETA18_09770	COG4846	Membrane protein involved in cytochrome C biogenesis
ETA18_09780	COG0071	Belongs to the small heat shock protein (HSP20) family
ETA18_09795	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ETA18_09800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA18_09820	COG0824	Thioesterase
ETA18_09830	COG4841	protein insertion into membrane
ETA18_09835	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ETA18_09840	COG1832	CoA-binding protein
ETA18_09845	COG0187	DNA topoisomerase II activity
ETA18_09850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETA18_09860	COG1115	amino acid carrier protein
ETA18_09865	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ETA18_09875	COG5520	Belongs to the glycosyl hydrolase 30 family
ETA18_09880	COG3507	Belongs to the glycosyl hydrolase 43 family
ETA18_09890	COG2246	polysaccharide biosynthetic process
ETA18_09895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETA18_09900	COG0586	Pfam SNARE associated Golgi protein
ETA18_09905	COG2404	hydrolase activity, acting on ester bonds
ETA18_09910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETA18_09915	COG1024	Enoyl-CoA hydratase
ETA18_09920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETA18_09925	COG0511	ligase activity, forming carbon-carbon bonds
ETA18_09930	COG0439	Biotin carboxylase
ETA18_09935	COG0318	PFAM AMP-dependent synthetase and ligase
ETA18_09940	COG1960	acyl-CoA dehydrogenase activity
ETA18_09955	COG1649	PFAM Uncharacterised BCR, COG1649
ETA18_09965	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ETA18_09965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_09970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_09975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_09980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_09990	COG2027	D-alanyl-D-alanine carboxypeptidase
ETA18_09995	COG2017	converts alpha-aldose to the beta-anomer
ETA18_10000	COG0534	Mate efflux family protein
ETA18_10015	COG0582	viral genome integration into host DNA
ETA18_10020	COG0166	Belongs to the GPI family
ETA18_10025	COG0405	Gamma-glutamyltransferase
ETA18_10030	COG0583	DNA-binding transcription factor activity
ETA18_10035	COG0604	alcohol dehydrogenase
ETA18_10040	COG0493	'glutamate synthase
ETA18_10045	COG0070	glutamate synthase
ETA18_10045	COG0067	glutamate synthase
ETA18_10045	COG0069	glutamate synthase activity
ETA18_10050	COG0583	DNA-binding transcription factor activity
ETA18_10055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETA18_10060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETA18_10070	COG0300	oxidoreductase activity
ETA18_10075	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ETA18_10085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA18_10090	COG2814	Major facilitator Superfamily
ETA18_10095	COG1070	Carbohydrate kinase
ETA18_10100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETA18_10105	COG0243	molybdopterin cofactor binding
ETA18_10135	COG5278	phosphoserine phosphatase activity
ETA18_10135	COG0840	transmembrane signaling receptor activity
ETA18_10140	COG2368	4-hydroxyphenylacetate
ETA18_10145	COG4305	rare lipoprotein A
ETA18_10150	COG3619	membrane
ETA18_10155	COG3866	Pectate lyase
ETA18_10160	COG2135	peptidase activity
ETA18_10170	COG2140	Oxalate decarboxylase
ETA18_10185	COG0456	acetyltransferase
ETA18_10205	COG2720	vancomycin resistance protein
ETA18_10215	COG3655	Transcriptional regulator
ETA18_10220	COG3739	integral membrane protein
ETA18_10225	COG0583	DNA-binding transcription factor activity
ETA18_10230	COG0697	spore germination
ETA18_10240	COG0693	protein deglycase activity
ETA18_10245	COG2367	Beta-lactamase
ETA18_10265	COG0574	Belongs to the PEP-utilizing enzyme family
ETA18_10265	COG3848	Pyruvate phosphate dikinase
ETA18_10270	COG0726	polysaccharide deacetylase
ETA18_10280	COG2314	TM2 domain
ETA18_10285	COG1396	sequence-specific DNA binding
ETA18_10405	COG0457	Tetratricopeptide repeat
ETA18_10415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETA18_10440	COG4282	regulation of fungal-type cell wall biogenesis
ETA18_10445	COG1231	oxidoreductase activity
ETA18_10450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETA18_10455	COG0662	Cupin 2, conserved barrel domain protein
ETA18_10455	COG2207	Transcriptional regulator
ETA18_10460	COG0456	acetyltransferase
ETA18_10465	COG1309	transcriptional regulator
ETA18_10470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA18_10475	COG3708	Transcriptional regulator
ETA18_10480	COG2378	regulation of single-species biofilm formation
ETA18_10490	COG0640	Transcriptional regulator
ETA18_10495	COG0741	lytic transglycosylase activity
ETA18_10500	COG2322	membrane
ETA18_10515	COG1619	proteins homologs of microcin C7 resistance protein MccF
ETA18_10520	COG3239	Fatty acid desaturase
ETA18_10525	COG4585	Histidine kinase
ETA18_10530	COG2197	response regulator
ETA18_10535	COG1388	LysM domain
ETA18_10535	COG3584	3D domain protein
ETA18_10540	COG0514	ATP-dependent DNA helicase (RecQ)
ETA18_10550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ETA18_10555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETA18_10570	COG0071	Belongs to the small heat shock protein (HSP20) family
ETA18_10595	COG1012	belongs to the aldehyde dehydrogenase family
ETA18_10600	COG1657	PFAM Prenyltransferase squalene oxidase
ETA18_10605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETA18_10610	COG0733	neurotransmitter:sodium symporter activity
ETA18_10615	COG0385	Bile acid
ETA18_10620	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETA18_10625	COG0567	Dehydrogenase, E1 component
ETA18_10630	COG4548	von Willebrand factor, type A
ETA18_10635	COG0714	Associated with various cellular activities
ETA18_10640	COG2032	superoxide dismutase activity
ETA18_10645	COG0791	NLP P60 protein
ETA18_10645	COG1388	LysM domain
ETA18_10650	COG1819	glycosyl
ETA18_10655	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETA18_10660	COG0534	Mate efflux family protein
ETA18_10665	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA18_10670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETA18_10675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETA18_10685	COG2962	Rard protein
ETA18_10700	COG2610	gluconate transmembrane transporter activity
ETA18_10705	COG1942	4-Oxalocrotonate Tautomerase
ETA18_10710	COG1733	regulation of RNA biosynthetic process
ETA18_10715	COG0778	Nitroreductase
ETA18_10720	COG0400	carboxylic ester hydrolase activity
ETA18_10725	COG0346	lactoylglutathione lyase activity
ETA18_10735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETA18_10740	COG3409	Peptidoglycan-binding domain 1 protein
ETA18_10740	COG0793	Belongs to the peptidase S41A family
ETA18_10745	COG2226	methyltransferase
ETA18_10755	COG1876	peptidase activity
ETA18_10760	COG0813	purine-nucleoside phosphorylase activity
ETA18_10775	COG0671	phosphoesterase, PA-phosphatase related
ETA18_10800	COG4479	Belongs to the UPF0346 family
ETA18_10810	COG1509	lysine 2,3-aminomutase activity
ETA18_10815	COG0456	acetyltransferase
ETA18_10820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETA18_10825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ETA18_10830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETA18_10835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETA18_10850	COG0456	acetyltransferase
ETA18_10855	COG0463	Glycosyl transferase, family 2
ETA18_10870	COG4641	Protein conserved in bacteria
ETA18_10875	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
ETA18_10880	COG1086	Polysaccharide biosynthesis protein
ETA18_10885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETA18_10890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETA18_10895	COG1846	Transcriptional regulator
ETA18_10900	COG0534	Mate efflux family protein
ETA18_10910	COG4698	Protein conserved in bacteria
ETA18_10915	COG2755	lipolytic protein G-D-S-L family
ETA18_10920	COG1999	signal sequence binding
ETA18_10930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETA18_10935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ETA18_10940	COG1272	protein, Hemolysin III
ETA18_10945	COG0204	Acyl-transferase
ETA18_10950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETA18_10955	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ETA18_10960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETA18_10970	COG2521	methyltransferase
ETA18_10970	COG2136	Putative SAM-dependent methyltransferase
ETA18_10980	COG0129	dihydroxy-acid dehydratase activity
ETA18_10985	COG1413	lyase activity
ETA18_10990	COG1418	mRNA catabolic process
ETA18_10995	COG0386	Belongs to the glutathione peroxidase family
ETA18_11000	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ETA18_11005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETA18_11015	COG1278	Cold shock
ETA18_11035	COG0328	RNA-DNA hybrid ribonuclease activity
ETA18_11040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ETA18_11045	COG0328	RNA-DNA hybrid ribonuclease activity
ETA18_11055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETA18_11070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ETA18_11080	COG1755	Isoprenylcysteine carboxyl methyltransferase
ETA18_11085	COG3424	synthase
ETA18_11090	COG2233	PERMEase
ETA18_11095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETA18_11100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ETA18_11110	COG0800	Aldolase
ETA18_11115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETA18_11120	COG1609	Transcriptional regulator
ETA18_11125	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ETA18_11130	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_11135	COG1199	ATP-dependent helicase activity
ETA18_11150	COG0116	Belongs to the methyltransferase superfamily
ETA18_11165	COG4474	Belongs to the UPF0398 family
ETA18_11180	COG3359	exonuclease
ETA18_11185	COG1205	dead DEAH box helicase
ETA18_11185	COG1111	helicase
ETA18_11190	COG2190	(PTS) system
ETA18_11195	COG0071	Belongs to the small heat shock protein (HSP20) family
ETA18_11230	COG3331	DNA recombination
ETA18_11235	COG4499	WXG100 protein secretion system (Wss), protein YukC
ETA18_11235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETA18_11245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ETA18_11250	COG3935	DnaD domain protein
ETA18_11255	COG0017	Asparaginyl-tRNA synthetase
ETA18_11260	COG0436	Aminotransferase
ETA18_11265	COG5353	protein conserved in bacteria
ETA18_11275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ETA18_11275	COG1199	ATP-dependent helicase activity
ETA18_11280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ETA18_11285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ETA18_11290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ETA18_11295	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ETA18_11295	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ETA18_11300	COG0617	tRNA 3'-terminal CCA addition
ETA18_11305	COG0438	transferase activity, transferring glycosyl groups
ETA18_11310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETA18_11315	COG1803	Methylglyoxal synthase
ETA18_11320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ETA18_11325	COG1694	Mazg nucleotide pyrophosphohydrolase
ETA18_11330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA18_11340	COG4347	Protein of unknown function (DUF1405)
ETA18_11345	COG2010	Cytochrome c
ETA18_11345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETA18_11350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETA18_11355	COG0723	plastoquinol--plastocyanin reductase activity
ETA18_11365	COG5582	Belongs to the UPF0302 family
ETA18_11370	COG0457	Tetratricopeptide repeat
ETA18_11375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ETA18_11380	COG0287	Prephenate dehydrogenase
ETA18_11385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ETA18_11390	COG0159	tryptophan synthase activity
ETA18_11395	COG0133	tryptophan synthase activity
ETA18_11400	COG0135	phosphoribosylanthranilate isomerase activity
ETA18_11410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ETA18_11415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETA18_11420	COG4401	Chorismate mutase type I
ETA18_11425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ETA18_11430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ETA18_11435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ETA18_11440	COG0105	UTP biosynthetic process
ETA18_11445	COG0142	geranyltranstransferase activity
ETA18_11450	COG2226	methyltransferase
ETA18_11455	COG0142	geranyltranstransferase activity
ETA18_11465	COG0302	gtp cyclohydrolase
ETA18_11470	COG0776	regulation of translation
ETA18_11475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ETA18_11490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ETA18_11495	COG1160	GTP binding
ETA18_11520	COG1304	FMN binding
ETA18_11525	COG0539	negative regulation of cytoplasmic translation
ETA18_11530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ETA18_11540	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ETA18_11545	COG2959	enzyme of heme biosynthesis
ETA18_11550	COG3409	Peptidoglycan-binding domain 1 protein
ETA18_11550	COG3773	Cell wall hydrolase
ETA18_11555	COG2339	peptidase activity
ETA18_11560	COG0492	ferredoxin-NADP+ reductase activity
ETA18_11565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETA18_11570	COG4862	establishment of competence for transformation
ETA18_11575	COG1408	metallophosphoesterase
ETA18_11585	COG1388	LysM domain
ETA18_11590	COG1266	CAAX protease self-immunity
ETA18_11595	COG0514	ATP-dependent DNA helicase (RecQ)
ETA18_11600	COG4955	Helix-turn-helix domain
ETA18_11605	COG1141	Ferredoxin
ETA18_11610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ETA18_11615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETA18_11620	COG0710	3-dehydroquinate dehydratase activity
ETA18_11630	COG1595	DNA-templated transcription, initiation
ETA18_11635	COG5002	protein histidine kinase activity
ETA18_11640	COG0745	RESPONSE REGULATOR receiver
ETA18_11645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETA18_11650	COG1333	cytochrome c biogenesis protein
ETA18_11655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA18_11660	COG1187	pseudouridine synthase activity
ETA18_11665	COG0700	Nucleoside recognition
ETA18_11670	COG2715	membrane protein required for spore maturation
ETA18_11675	COG1686	Belongs to the peptidase S11 family
ETA18_11685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ETA18_11690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ETA18_11695	COG1547	Domain of unknown function (DUF309)
ETA18_11700	COG0456	acetyltransferase
ETA18_11705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ETA18_11710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ETA18_11710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ETA18_11715	COG0307	riboflavin synthase, alpha
ETA18_11720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETA18_11720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETA18_11730	COG0681	Belongs to the peptidase S26 family
ETA18_11740	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
ETA18_11790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETA18_11800	COG4086	secreted protein
ETA18_11805	COG0019	diaminopimelate decarboxylase activity
ETA18_11810	COG0697	spore germination
ETA18_11825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETA18_11845	COG1191	sigma factor activity
ETA18_11850	COG2172	sigma factor antagonist activity
ETA18_11855	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA18_11860	COG1686	Belongs to the peptidase S11 family
ETA18_11865	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ETA18_11870	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ETA18_11875	COG4974	Belongs to the 'phage' integrase family
ETA18_11885	COG0735	belongs to the Fur family
ETA18_11890	COG1300	Membrane
ETA18_11900	COG0281	malic enzyme
ETA18_11905	COG1757	Na H antiporter
ETA18_11910	COG1027	Aspartate ammonia-lyase
ETA18_11915	COG0252	asparaginase activity
ETA18_11920	COG1396	sequence-specific DNA binding
ETA18_11925	COG1379	DNA repair
ETA18_11930	COG0494	nUDIX hydrolase
ETA18_11940	COG0667	Aldo Keto reductase
ETA18_11950	COG1073	alpha beta
ETA18_11960	COG4918	Iron-sulphur cluster biosynthesis
ETA18_11965	COG0456	acetyltransferase
ETA18_11965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ETA18_11970	COG2329	Antibiotic biosynthesis monooxygenase
ETA18_11975	COG0456	acetyltransferase
ETA18_11985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETA18_11995	COG2211	Major facilitator Superfamily
ETA18_12000	COG0346	lactoylglutathione lyase activity
ETA18_12005	COG1072	(Pantothenic acid kinase))
ETA18_12010	COG3048	D-serine ammonia-lyase activity
ETA18_12015	COG0300	oxidoreductase activity
ETA18_12020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA18_12025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETA18_12030	COG4187	Peptidase family M20/M25/M40
ETA18_12035	COG1902	pentaerythritol trinitrate reductase activity
ETA18_12040	COG0596	Alpha beta hydrolase
ETA18_12050	COG1234	tRNA 3'-trailer cleavage
ETA18_12055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ETA18_12060	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETA18_12065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETA18_12075	COG0706	membrane insertase activity
ETA18_12080	COG3361	conserved protein (COG2071)
ETA18_12085	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETA18_12090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETA18_12095	COG0346	lactoylglutathione lyase activity
ETA18_12100	COG1376	ErfK ybiS ycfS ynhG family protein
ETA18_12105	COG4129	membrane
ETA18_12110	COG1126	abc transporter atp-binding protein
ETA18_12115	COG0765	amino acid transport
ETA18_12120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETA18_12130	COG1597	lipid kinase activity
ETA18_12135	COG2814	Major facilitator Superfamily
ETA18_12140	COG0789	Transcriptional regulator
ETA18_12140	COG4978	Transcriptional regulator
ETA18_12145	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETA18_12150	COG0022	dehydrogenase e1 component
ETA18_12155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETA18_12160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETA18_12165	COG3426	butyrate kinase activity
ETA18_12170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETA18_12175	COG0280	phosphate acetyltransferase
ETA18_12180	COG3829	transcription factor binding
ETA18_12180	COG3290	protein histidine kinase activity
ETA18_12190	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ETA18_12195	COG2079	MmgE PrpD family protein
ETA18_12200	COG0372	Belongs to the citrate synthase family
ETA18_12205	COG1960	acyl-CoA dehydrogenase activity
ETA18_12210	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETA18_12215	COG0183	Belongs to the thiolase family
ETA18_12220	COG0584	glycerophosphoryl diester phosphodiesterase
ETA18_12225	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA18_12240	COG1902	pentaerythritol trinitrate reductase activity
ETA18_12245	COG0745	RESPONSE REGULATOR receiver
ETA18_12250	COG0750	zinc metalloprotease
ETA18_12255	COG0497	DNA recombination
ETA18_12260	COG1438	arginine binding
ETA18_12265	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ETA18_12270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ETA18_12275	COG0142	geranyltranstransferase activity
ETA18_12280	COG1722	exodeoxyribonuclease VII activity
ETA18_12285	COG1570	exodeoxyribonuclease VII activity
ETA18_12290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ETA18_12295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETA18_12300	COG1302	Protein conserved in bacteria
ETA18_12305	COG0439	Biotin carboxylase
ETA18_12310	COG0511	ligase activity, forming carbon-carbon bonds
ETA18_12350	COG3854	ATPases associated with a variety of cellular activities
ETA18_12360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ETA18_12365	COG0006	proline dipeptidase activity
ETA18_12370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ETA18_12380	COG3872	metal-dependent enzyme
ETA18_12390	COG1752	Esterase of the alpha-beta hydrolase superfamily
ETA18_12395	COG1321	iron dependent repressor
ETA18_12400	COG0095	Lipoate-protein ligase
ETA18_12405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETA18_12410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETA18_12415	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETA18_12420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ETA18_12425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETA18_12440	COG1396	sequence-specific DNA binding
ETA18_12450	COG0681	Belongs to the peptidase S26 family
ETA18_12475	COG4940	Competence protein ComGF
ETA18_12485	COG4970	Tfp pilus assembly protein FimT
ETA18_12490	COG4537	Required for transformation and DNA binding
ETA18_12495	COG1459	type II secretion system
ETA18_12500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETA18_12510	COG0598	Magnesium transport protein CorA
ETA18_12515	COG1253	flavin adenine dinucleotide binding
ETA18_12520	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA18_12530	COG1393	Belongs to the ArsC family
ETA18_12540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA18_12550	COG0011	TIGRFAM Protein of
ETA18_12560	COG2866	Carboxypeptidase
ETA18_12565	COG1368	sulfuric ester hydrolase activity
ETA18_12570	COG1940	carbohydrate kinase activity
ETA18_12575	COG4483	Protein conserved in bacteria
ETA18_12580	COG0705	Rhomboid family
ETA18_12580	COG0457	Tetratricopeptide repeat
ETA18_12590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ETA18_12595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ETA18_12600	COG0438	transferase activity, transferring glycosyl groups
ETA18_12615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETA18_12620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETA18_12625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETA18_12630	COG0581	inorganic phosphate transmembrane transporter activity
ETA18_12635	COG0573	inorganic phosphate transmembrane transporter activity
ETA18_12640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ETA18_12650	COG0477	Major facilitator Superfamily
ETA18_12655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETA18_12660	COG2839	Protein conserved in bacteria
ETA18_12665	COG5521	maltodextrose utilization protein MalA
ETA18_12670	COG1388	LysM domain
ETA18_12675	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ETA18_12680	COG4709	membrane
ETA18_12685	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
ETA18_12690	COG0735	belongs to the Fur family
ETA18_12695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA18_12705	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ETA18_12710	COG0513	Belongs to the DEAD box helicase family
ETA18_12720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ETA18_12725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ETA18_12730	COG2384	SAM-dependent methyltransferase
ETA18_12735	COG2010	Cytochrome c
ETA18_12745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETA18_12750	COG0358	DNA primase activity
ETA18_12755	COG1671	Belongs to the UPF0178 family
ETA18_12760	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ETA18_12765	COG0517	IMP dehydrogenase activity
ETA18_12770	COG0751	glycine-tRNA ligase activity
ETA18_12775	COG0752	glycyl-tRNA synthetase alpha subunit
ETA18_12780	COG1381	Involved in DNA repair and RecF pathway recombination
ETA18_12790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ETA18_12795	COG0295	cytidine deaminase activity
ETA18_12800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ETA18_12805	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ETA18_12810	COG1480	7TM receptor with intracellular HD hydrolase
ETA18_12815	COG1702	phosphate starvation-inducible protein PhoH
ETA18_12820	COG0561	phosphatase activity
ETA18_12835	COG4864	UPF0365 protein
ETA18_12840	COG1030	water channel activity
ETA18_12845	COG1610	YqeY-like protein
ETA18_12850	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ETA18_12855	COG1283	sodium-dependent phosphate transmembrane transporter activity
ETA18_12860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETA18_12865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETA18_12870	COG2264	protein methyltransferase activity
ETA18_12875	COG0484	heat shock protein binding
ETA18_12880	COG0443	Heat shock 70 kDa protein
ETA18_12885	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ETA18_12890	COG1420	regulation of RNA biosynthetic process
ETA18_12895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETA18_12900	COG0481	GTPase activity
ETA18_12910	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA18_12915	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ETA18_12920	COG0268	Binds directly to 16S ribosomal RNA
ETA18_12925	COG1466	dna polymerase III delta subunit
ETA18_12940	COG0658	competence protein
ETA18_12940	COG2333	competence protein COMEC
ETA18_12945	COG2131	deaminase
ETA18_12950	COG1596	polysaccharide export
ETA18_12950	COG1555	photosystem II stabilization
ETA18_12955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETA18_12960	COG2226	methyltransferase
ETA18_12965	COG0799	negative regulation of ribosome biogenesis
ETA18_12970	COG1713	HD superfamily hydrolase involved in NAD metabolism
ETA18_12975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ETA18_12980	COG1534	Rna-binding protein
ETA18_12985	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETA18_12990	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETA18_12995	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ETA18_13005	COG2755	lipolytic protein G-D-S-L family
ETA18_13015	COG3409	Peptidoglycan-binding domain 1 protein
ETA18_13015	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETA18_13020	COG0398	Pfam SNARE associated Golgi protein
ETA18_13025	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ETA18_13035	COG3209	COG3209 Rhs family protein
ETA18_13045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETA18_13060	COG0604	alcohol dehydrogenase
ETA18_13070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETA18_13075	COG0798	PFAM Bile acid sodium symporter
ETA18_13080	COG0346	lactoylglutathione lyase activity
ETA18_13085	COG0640	Transcriptional regulator
ETA18_13090	COG0457	Tetratricopeptide repeat
ETA18_13100	COG5444	nuclease activity
ETA18_13130	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETA18_13130	COG3409	Peptidoglycan-binding domain 1 protein
ETA18_13135	COG4824	toxin secretion phage lysis holin
ETA18_13165	COG3778	Protein conserved in bacteria
ETA18_13170	COG3299	homolog of phage Mu protein gp47
ETA18_13175	COG3628	GPW Gp25 family protein
ETA18_13180	COG1794	racemase activity, acting on amino acids and derivatives
ETA18_13190	COG4193	domain, Protein
ETA18_13195	COG1652	LysM domain
ETA18_13200	COG3953	SLT domain
ETA18_13200	COG5280	Phage tail tape measure protein TP901
ETA18_13260	COG4653	Phage capsid family
ETA18_13265	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ETA18_13275	COG2369	cell adhesion
ETA18_13280	COG5518	Phage portal protein
ETA18_13285	COG1783	phage Terminase large subunit
ETA18_13290	COG5484	DNA packaging
ETA18_13325	COG3677	Transposase
ETA18_13350	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ETA18_13360	COG1484	DNA-dependent DNA replication
ETA18_13365	COG3935	DnaD domain protein
ETA18_13370	COG3723	Recombinational DNA repair protein, rece pathway
ETA18_13375	COG5377	YqaJ viral recombinase family
ETA18_13410	COG3620	sequence-specific DNA binding
ETA18_13420	COG0563	adenylate kinase activity
ETA18_13425	COG2856	Zn peptidase
ETA18_13445	COG4124	Belongs to the glycosyl hydrolase 26 family
ETA18_13450	COG0730	response to heat
ETA18_13455	COG0425	Belongs to the sulfur carrier protein TusA family
ETA18_13460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETA18_13460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA18_13470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETA18_13470	COG0425	Belongs to the sulfur carrier protein TusA family
ETA18_13480	COG2210	Belongs to the sulfur carrier protein TusA family
ETA18_13485	COG1937	Protein conserved in bacteria
ETA18_13500	COG0662	Cupin 2, conserved barrel domain protein
ETA18_13515	COG0789	Transcriptional regulator
ETA18_13515	COG4978	Transcriptional regulator
ETA18_13520	COG2814	Major facilitator Superfamily
ETA18_13525	COG0456	acetyltransferase
ETA18_13530	COG1253	flavin adenine dinucleotide binding
ETA18_13540	COG0697	spore germination
ETA18_13545	COG0583	DNA-binding transcription factor activity
ETA18_13550	COG2072	flavoprotein involved in K transport
ETA18_13555	COG1230	cation diffusion facilitator family transporter
ETA18_13560	COG1942	4-Oxalocrotonate Tautomerase
ETA18_13565	COG0583	DNA-binding transcription factor activity
ETA18_13575	COG1114	Component of the transport system for branched-chain amino acids
ETA18_13580	COG1687	branched-chain amino acid
ETA18_13585	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ETA18_13590	COG1522	sequence-specific DNA binding
ETA18_13600	COG2124	cytochrome p450
ETA18_13610	COG1335	isochorismatase
ETA18_13625	COG2318	DinB family
ETA18_13635	COG2070	2-Nitropropane dioxygenase
ETA18_13650	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ETA18_13670	COG3443	Belongs to the bacterial solute-binding protein 9 family
ETA18_13680	COG0667	Aldo Keto reductase
ETA18_13685	COG2851	Citrate transporter
ETA18_13690	COG0583	DNA-binding transcription factor activity
ETA18_13695	COG2828	Protein conserved in bacteria
ETA18_13700	COG3409	Peptidoglycan-binding domain 1 protein
ETA18_13705	COG5566	PFAM Mor transcription activator
ETA18_13710	COG0596	Alpha beta hydrolase
ETA18_13715	COG4991	sh3 domain protein
ETA18_13720	COG4991	sh3 domain protein
ETA18_13725	COG0346	lactoylglutathione lyase activity
ETA18_13735	COG5577	PFAM Coat F domain
ETA18_13740	COG1063	alcohol dehydrogenase
ETA18_13750	COG5577	PFAM Coat F domain
ETA18_13755	COG0789	Transcriptional regulator
ETA18_13765	COG1064	alcohol dehydrogenase
ETA18_13770	COG0693	protein deglycase activity
ETA18_13775	COG1621	beta-fructofuranosidase activity
ETA18_13780	COG3716	PTS system mannose fructose sorbose family IID component
ETA18_13785	COG3715	PTS system
ETA18_13790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_13795	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA18_13800	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ETA18_13800	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ETA18_13810	COG1113	amino acid transport
ETA18_13815	COG1280	lysine exporter protein (LysE YggA)
ETA18_13820	COG1378	Sugar-specific transcriptional regulator TrmB
ETA18_13825	COG1595	DNA-templated transcription, initiation
ETA18_13835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETA18_13835	COG2755	lipolytic protein G-D-S-L family
ETA18_13845	COG2124	cytochrome p450
ETA18_13845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETA18_13850	COG1309	transcriptional regulator
ETA18_13855	COG2226	methyltransferase
ETA18_13870	COG2116	formate transmembrane transporter activity
ETA18_13875	COG5609	conserved protein (DUF2294)
ETA18_13880	COG3383	formate dehydrogenase (NAD+) activity
ETA18_13885	COG2427	Protein of unknown function (DUF1641)
ETA18_13895	COG0626	cystathionine gamma-synthase activity
ETA18_13900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETA18_13905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ETA18_13910	COG2226	methyltransferase
ETA18_13925	COG0768	penicillin binding
ETA18_13930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ETA18_13935	COG0572	uridine kinase
ETA18_13955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETA18_13960	COG3906	Belongs to the UPF0473 family
ETA18_13965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ETA18_13970	COG4472	Bacterial protein of unknown function (DUF965)
ETA18_13975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ETA18_13980	COG0628	permease
ETA18_13985	COG1126	abc transporter atp-binding protein
ETA18_13990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETA18_13995	COG0765	amino acid transport
ETA18_14000	COG0765	amino acid transport
ETA18_14015	COG3881	PFAM PRC-barrel domain
ETA18_14020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETA18_14025	COG0457	Tetratricopeptide repeat
ETA18_14030	COG0482	sulfurtransferase activity
ETA18_14035	COG1104	cysteine desulfurase activity
ETA18_14040	COG1959	2 iron, 2 sulfur cluster binding
ETA18_14045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ETA18_14050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ETA18_14060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ETA18_14065	COG0124	histidyl-tRNA synthetase
ETA18_14075	COG4991	sh3 domain protein
ETA18_14075	COG3103	Sh3 type 3 domain protein
ETA18_14075	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA18_14080	COG1490	D-aminoacyl-tRNA deacylase activity
ETA18_14085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ETA18_14090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETA18_14095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ETA18_14095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETA18_14100	COG5416	Lipopolysaccharide assembly protein A domain
ETA18_14105	COG0490	domain, Protein
ETA18_14110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETA18_14110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETA18_14120	COG2244	polysaccharide biosynthetic process
ETA18_14125	COG2323	membrane
ETA18_14135	COG1862	Preprotein translocase
ETA18_14140	COG0343	queuine tRNA-ribosyltransferase activity
ETA18_14145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ETA18_14155	COG2255	four-way junction helicase activity
ETA18_14160	COG0632	four-way junction helicase activity
ETA18_14170	COG2814	Major facilitator Superfamily
ETA18_14175	COG0673	inositol 2-dehydrogenase activity
ETA18_14180	COG2112	serine threonine protein kinase
ETA18_14200	COG1115	amino acid carrier protein
ETA18_14205	COG0217	transcriptional regulatory protein
ETA18_14215	COG1388	LysM domain
ETA18_14220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ETA18_14225	COG0157	Belongs to the NadC ModD family
ETA18_14230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ETA18_14235	COG1104	cysteine desulfurase activity
ETA18_14240	COG1827	regulation of RNA biosynthetic process
ETA18_14245	COG0077	Prephenate dehydratase
ETA18_14250	COG4492	Belongs to the UPF0735 family
ETA18_14255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ETA18_14260	COG3290	protein histidine kinase activity
ETA18_14270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETA18_14275	COG2868	ribosomal protein
ETA18_14280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ETA18_14285	COG1994	Peptidase M50
ETA18_14290	COG0739	heme binding
ETA18_14295	COG2894	cell division
ETA18_14300	COG0850	regulation of cytokinetic process
ETA18_14305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ETA18_14310	COG1792	Involved in formation and maintenance of cell shape
ETA18_14315	COG1077	Cell shape determining protein MreB Mrl
ETA18_14320	COG2003	Belongs to the UPF0758 family
ETA18_14325	COG0424	maF-like protein
ETA18_14335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ETA18_14340	COG0285	dihydrofolate synthase activity
ETA18_14345	COG0525	valine-tRNA ligase activity
ETA18_14355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETA18_14360	COG1388	LysM domain
ETA18_14365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETA18_14370	COG0113	porphobilinogen synthase activity
ETA18_14375	COG1587	Uroporphyrinogen-III synthase
ETA18_14380	COG0181	hydroxymethylbilane synthase activity
ETA18_14385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETA18_14390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ETA18_14400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ETA18_14405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ETA18_14410	COG1067	ATP-dependent peptidase activity
ETA18_14410	COG0470	DNA polymerase III
ETA18_14415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ETA18_14420	COG0544	peptidyl-prolyl cis-trans isomerase activity
ETA18_14425	COG1477	protein flavinylation
ETA18_14425	COG0457	Tetratricopeptide repeat
ETA18_14430	COG0066	3-isopropylmalate dehydratase activity
ETA18_14435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ETA18_14440	COG0473	3-isopropylmalate dehydrogenase activity
ETA18_14445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETA18_14450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ETA18_14455	COG0440	acetolactate synthase activity
ETA18_14460	COG0028	Belongs to the TPP enzyme family
ETA18_14470	COG0454	-acetyltransferase
ETA18_14475	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
ETA18_14485	COG0622	Phosphoesterase
ETA18_14490	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ETA18_14495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ETA18_14500	COG5401	PFAM Sporulation and spore germination
ETA18_14505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ETA18_14510	COG1846	Transcriptional regulator
ETA18_14515	COG2197	response regulator
ETA18_14520	COG0824	Thioesterase
ETA18_14525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETA18_14530	COG1053	succinate dehydrogenase
ETA18_14535	COG2009	succinate dehydrogenase
ETA18_14540	COG1719	4-vinyl reductase, 4VR
ETA18_14545	COG0527	aspartate kinase activity
ETA18_14555	COG0322	excinuclease ABC activity
ETA18_14560	COG3118	belongs to the thioredoxin family
ETA18_14570	COG3534	alpha-L-arabinofuranosidase
ETA18_14575	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ETA18_14580	COG2086	electron transfer activity
ETA18_14585	COG1024	Enoyl-CoA hydratase
ETA18_14590	COG1309	transcriptional regulator
ETA18_14595	COG0318	PFAM AMP-dependent synthetase and ligase
ETA18_14600	COG3766	membrane
ETA18_14605	COG1193	negative regulation of DNA recombination
ETA18_14610	COG1796	DNA polymerase
ETA18_14610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETA18_14615	COG1286	toxin biosynthetic process
ETA18_14620	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ETA18_14625	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ETA18_14630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETA18_14630	COG0072	phenylalanine-tRNA ligase activity
ETA18_14635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ETA18_14645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETA18_14655	COG3835	regulator
ETA18_14660	COG0277	FAD linked oxidase domain protein
ETA18_14665	COG0247	lactate metabolic process
ETA18_14670	COG0346	lactoylglutathione lyase activity
ETA18_14680	COG1966	Carbon starvation protein
ETA18_14685	COG3534	alpha-L-arabinofuranosidase
ETA18_14690	COG0395	ABC-type sugar transport system, permease component
ETA18_14695	COG1175	transmembrane transport
ETA18_14700	COG1653	transport
ETA18_14705	COG0371	Dehydrogenase
ETA18_14710	COG0647	UMP catabolic process
ETA18_14715	COG0235	Class ii aldolase
ETA18_14720	COG1069	ribulokinase activity
ETA18_14725	COG2160	L-arabinose isomerase activity
ETA18_14730	COG3507	Belongs to the glycosyl hydrolase 43 family
ETA18_14735	COG1363	Peptidase, m42
ETA18_14745	COG3326	Membrane
ETA18_14750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ETA18_14755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ETA18_14760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ETA18_14770	COG1346	cytolysis
ETA18_14775	COG1380	Effector of murein hydrolase LrgA
ETA18_14780	COG3279	Response regulator of the LytR AlgR family
ETA18_14785	COG3275	phosphorelay sensor kinase activity
ETA18_14795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETA18_14805	COG0398	Pfam SNARE associated Golgi protein
ETA18_14810	COG1484	DNA-dependent DNA replication
ETA18_14815	COG3611	Membrane attachment protein
ETA18_14820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETA18_14825	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ETA18_14830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETA18_14835	COG1733	regulation of RNA biosynthetic process
ETA18_14840	COG2814	Major facilitator Superfamily
ETA18_14845	COG0656	L-ascorbic acid biosynthetic process
ETA18_14850	COG0237	dephospho-CoA kinase activity
ETA18_14855	COG1971	Probably functions as a manganese efflux pump
ETA18_14860	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ETA18_14865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETA18_14865	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETA18_14870	COG5002	protein histidine kinase activity
ETA18_14875	COG0745	RESPONSE REGULATOR receiver
ETA18_14880	COG0039	L-malate dehydrogenase activity
ETA18_14885	COG0538	isocitrate dehydrogenase activity
ETA18_14890	COG0372	Belongs to the citrate synthase family
ETA18_14895	COG2707	UPF0756 membrane protein
ETA18_14900	COG0628	permease
ETA18_14905	COG3030	protein affecting phage T7 exclusion by the F plasmid
ETA18_14910	COG0469	pyruvate kinase activity
ETA18_14915	COG0205	6-phosphofructokinase activity
ETA18_14920	COG0825	malonyl-CoA metabolic process
ETA18_14925	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ETA18_14930	COG0281	malic enzyme
ETA18_14935	COG0587	DNA-directed DNA polymerase activity
ETA18_14955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ETA18_14965	COG4109	DRTGG domain
ETA18_14970	COG0730	response to heat
ETA18_14975	COG1473	amidohydrolase
ETA18_14980	COG0196	riboflavin kinase activity
ETA18_14985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETA18_14990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ETA18_14995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETA18_15000	COG1126	abc transporter atp-binding protein
ETA18_15005	COG0765	amino acid transport
ETA18_15010	COG0765	amino acid transport
ETA18_15015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETA18_15020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETA18_15025	COG0454	-acetyltransferase
ETA18_15030	COG0583	DNA-binding transcription factor activity
ETA18_15035	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ETA18_15040	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_15050	COG0165	Argininosuccinate lyase
ETA18_15055	COG0137	argininosuccinate synthase activity
ETA18_15060	COG0521	Mo-molybdopterin cofactor biosynthetic process
ETA18_15065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ETA18_15075	COG0827	DNA restriction-modification system
ETA18_15080	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ETA18_15085	COG3874	Sporulation protein YtfJ
ETA18_15095	COG1714	RDD family
ETA18_15100	COG0616	signal peptide processing
ETA18_15105	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETA18_15110	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ETA18_15115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETA18_15125	COG0301	tRNA thio-modification
ETA18_15130	COG1104	cysteine desulfurase activity
ETA18_15135	COG1114	Component of the transport system for branched-chain amino acids
ETA18_15140	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ETA18_15145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETA18_15150	COG1309	transcriptional regulator
ETA18_15155	COG1956	GAF domain-containing protein
ETA18_15160	COG2203	Gaf domain
ETA18_15160	COG2199	diguanylate cyclase activity
ETA18_15170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ETA18_15175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETA18_15180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETA18_15185	COG0454	-acetyltransferase
ETA18_15190	COG0517	IMP dehydrogenase activity
ETA18_15195	COG0123	including yeast histone deacetylase and acetoin utilization protein
ETA18_15200	COG1360	Flagellar Motor Protein
ETA18_15205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ETA18_15210	COG1609	Transcriptional regulator
ETA18_15215	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETA18_15215	COG1605	Chorismate mutase
ETA18_15220	COG3118	belongs to the thioredoxin family
ETA18_15225	COG4980	gas vesicle protein
ETA18_15230	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ETA18_15235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ETA18_15240	COG1674	ftsk spoiiie
ETA18_15245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETA18_15250	COG4848	Belongs to the UPF0354 family
ETA18_15255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA18_15270	COG1363	Peptidase, m42
ETA18_15275	COG5584	Small secreted protein
ETA18_15280	COG0281	malic enzyme
ETA18_15285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA18_15290	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ETA18_15300	COG0510	thiamine kinase activity
ETA18_15305	COG1523	belongs to the glycosyl hydrolase 13 family
ETA18_15310	COG1597	lipid kinase activity
ETA18_15320	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETA18_15325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETA18_15330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETA18_15335	COG2252	PERMEase
ETA18_15340	COG4473	ABC transporter
ETA18_15345	COG1131	(ABC) transporter
ETA18_15350	COG1349	DNA-binding transcription factor activity
ETA18_15355	COG1187	pseudouridine synthase activity
ETA18_15360	COG2244	polysaccharide biosynthetic process
ETA18_15365	COG2081	HI0933 family
ETA18_15370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ETA18_15380	COG5578	integral membrane protein
ETA18_15385	COG0673	inositol 2-dehydrogenase activity
ETA18_15390	COG1653	transport
ETA18_15395	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETA18_15400	COG4209	transmembrane transport
ETA18_15405	COG2207	Transcriptional regulator
ETA18_15410	COG1653	transport
ETA18_15415	COG0395	ABC-type sugar transport system, permease component
ETA18_15420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETA18_15425	COG2124	cytochrome p450
ETA18_15430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ETA18_15440	COG0156	8-amino-7-oxononanoate synthase activity
ETA18_15445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETA18_15455	COG1073	alpha beta
ETA18_15480	COG1486	melibiose metabolic process
ETA18_15485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETA18_15490	COG0495	leucyl-tRNA aminoacylation
ETA18_15500	COG2202	Pas domain
ETA18_15500	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA18_15505	COG2814	Major facilitator Superfamily
ETA18_15510	COG2433	Pfam Transposase IS66
ETA18_15515	COG0577	efflux transmembrane transporter activity
ETA18_15520	COG1136	(ABC) transporter
ETA18_15525	COG2205	protein histidine kinase activity
ETA18_15530	COG0745	RESPONSE REGULATOR receiver
ETA18_15535	COG0577	efflux transmembrane transporter activity
ETA18_15540	COG1136	(ABC) transporter
ETA18_15555	COG1131	(ABC) transporter
ETA18_15560	COG1725	Transcriptional regulator
ETA18_15575	COG1242	4 iron, 4 sulfur cluster binding
ETA18_15580	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ETA18_15590	COG2267	carboxylic ester hydrolase activity
ETA18_15595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ETA18_15600	COG1113	amino acid transport
ETA18_15605	COG0367	asparagine synthase
ETA18_15610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ETA18_15615	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ETA18_15625	COG1506	peptidase
ETA18_15630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETA18_15635	COG1116	anion transmembrane transporter activity
ETA18_15640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETA18_15645	COG0494	nUDIX hydrolase
ETA18_15650	COG4824	toxin secretion phage lysis holin
ETA18_15655	COG0783	Belongs to the Dps family
ETA18_15670	COG1854	S-ribosylhomocysteine lyase activity
ETA18_15675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ETA18_15680	COG0288	reversible hydration of carbon dioxide
ETA18_15685	COG0254	rRNA binding
ETA18_15690	COG1271	oxidase subunit
ETA18_15695	COG1294	oxidase, subunit
ETA18_15705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETA18_15710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETA18_15710	COG1321	iron dependent repressor
ETA18_15715	COG1121	(ABC) transporter
ETA18_15720	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETA18_15730	COG4948	Mandelate Racemase Muconate Lactonizing
ETA18_15735	COG0318	PFAM AMP-dependent synthetase and ligase
ETA18_15740	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ETA18_15745	COG0596	Alpha beta hydrolase
ETA18_15750	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ETA18_15755	COG1169	isochorismate synthase
ETA18_15765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETA18_15770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETA18_15775	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETA18_15780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETA18_15785	COG0438	transferase activity, transferring glycosyl groups
ETA18_15795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETA18_15800	COG0438	transferase activity, transferring glycosyl groups
ETA18_15805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETA18_15810	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETA18_15815	COG0058	SHG alpha-glucan phosphorylase activity
ETA18_15820	COG0297	glycogen (starch) synthase activity
ETA18_15825	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETA18_15830	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETA18_15835	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETA18_15960	COG3859	Proton-coupled thiamine transporter YuaJ
ETA18_15965	COG1247	-acetyltransferase
ETA18_15970	COG2268	Band 7 protein
ETA18_15975	COG1585	Membrane protein implicated in regulation of membrane protease activity
ETA18_15980	COG2318	DinB family
ETA18_15990	COG1454	alcohol dehydrogenase
ETA18_16000	COG1510	regulation of RNA biosynthetic process
ETA18_16010	COG0569	domain protein
ETA18_16015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETA18_16020	COG4682	membrane
ETA18_16025	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETA18_16030	COG0477	Major facilitator Superfamily
ETA18_16035	COG5553	Cysteine dioxygenase type I
ETA18_16045	COG1968	undecaprenyl-diphosphatase activity
ETA18_16050	COG0628	permease
ETA18_16055	COG0673	inositol 2-dehydrogenase activity
ETA18_16060	COG4806	L-rhamnose isomerase
ETA18_16065	COG3254	rhamnose metabolic process
ETA18_16070	COG1070	Carbohydrate kinase
ETA18_16075	COG1349	DNA-binding transcription factor activity
ETA18_16080	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_16080	COG3347	Dehydrogenase
ETA18_16090	COG0840	transmembrane signaling receptor activity
ETA18_16095	COG0840	transmembrane signaling receptor activity
ETA18_16100	COG0840	transmembrane signaling receptor activity
ETA18_16105	COG0840	transmembrane signaling receptor activity
ETA18_16120	COG0432	Pfam Uncharacterised protein family UPF0047
ETA18_16130	COG0366	Alpha amylase catalytic
ETA18_16135	COG1253	flavin adenine dinucleotide binding
ETA18_16140	COG2738	Putative neutral zinc metallopeptidase
ETA18_16155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ETA18_16170	COG0166	Belongs to the GPI family
ETA18_16175	COG1979	alcohol dehydrogenase
ETA18_16180	COG1979	alcohol dehydrogenase
ETA18_16185	COG2155	Conserved Protein
ETA18_16190	COG1098	S1 RNA binding domain
ETA18_16195	COG0436	Aminotransferase
ETA18_16200	COG1522	sequence-specific DNA binding
ETA18_16205	COG2267	carboxylic ester hydrolase activity
ETA18_16215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ETA18_16220	COG2205	protein histidine kinase activity
ETA18_16230	COG5018	Exonuclease
ETA18_16240	COG2814	Major facilitator Superfamily
ETA18_16245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETA18_16250	COG3011	Protein conserved in bacteria
ETA18_16260	COG3290	protein histidine kinase activity
ETA18_16265	COG4565	transcriptional regulatory protein
ETA18_16290	COG3493	citrate carrier protein
ETA18_16300	COG2111	Na H antiporter
ETA18_16300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETA18_16305	COG2111	Na H antiporter
ETA18_16310	COG1006	Multisubunit Na H antiporter MnhC subunit
ETA18_16315	COG0651	ATP synthesis coupled electron transport
ETA18_16320	COG1863	multisubunit Na H antiporter MnhE subunit
ETA18_16325	COG2212	antiporter activity
ETA18_16330	COG1320	monovalent cation:proton antiporter activity
ETA18_16335	COG2050	protein possibly involved in aromatic compounds catabolism
ETA18_16340	COG2197	response regulator
ETA18_16345	COG4585	Histidine kinase
ETA18_16355	COG0142	geranyltranstransferase activity
ETA18_16375	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ETA18_16380	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ETA18_16385	COG1335	isochorismatase
ETA18_16390	COG5506	Protein of unknown function (DUF1694)
ETA18_16405	COG0628	permease
ETA18_16420	COG1418	mRNA catabolic process
ETA18_16425	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_16435	COG1511	domain protein
ETA18_16440	COG0433	COG0433 Predicted ATPase
ETA18_16440	COG1674	ftsk spoiiie
ETA18_16445	COG4499	WXG100 protein secretion system (Wss), protein YukC
ETA18_16450	COG5417	Belongs to the EsaB family
ETA18_16455	COG4842	Belongs to the WXG100 family
ETA18_16465	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ETA18_16465	COG2508	Transcriptional regulator
ETA18_16470	COG0686	Belongs to the AlaDH PNT family
ETA18_16475	COG5634	Uncharacterized conserved protein (DUF2278)
ETA18_16480	COG3251	PFAM MbtH domain protein
ETA18_16485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_16490	COG1535	isochorismatase
ETA18_16490	COG3433	isochorismatase activity
ETA18_16495	COG1021	2,3-dihydroxybenzoate-AMP ligase
ETA18_16500	COG1169	isochorismate synthase
ETA18_16505	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_16510	COG2819	hydrolase of the alpha beta superfamily
ETA18_16515	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETA18_16520	COG1268	BioY protein
ETA18_16525	COG2056	Na+-H+ antiporter family
ETA18_16530	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ETA18_16535	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ETA18_16540	COG3584	3D domain protein
ETA18_16555	COG1252	NADH dehydrogenase
ETA18_16560	COG0492	ferredoxin-NADP+ reductase activity
ETA18_16570	COG0516	GMP reductase activity
ETA18_16575	COG2808	Putative FMN-binding domain
ETA18_16580	COG0456	acetyltransferase
ETA18_16585	COG0316	Belongs to the HesB IscA family
ETA18_16590	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ETA18_16595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETA18_16600	COG4844	belongs to the
ETA18_16605	COG1252	NADH dehydrogenase
ETA18_16610	COG4837	Protein of unknown function (DUF1462)
ETA18_16615	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ETA18_16620	COG1506	peptidase
ETA18_16620	COG0823	Involved in the tonB-independent uptake of proteins
ETA18_16620	COG4946	Tricorn protease homolog
ETA18_16625	COG0083	homoserine kinase activity
ETA18_16630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETA18_16635	COG0460	homoserine dehydrogenase
ETA18_16640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETA18_16645	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETA18_16650	COG0647	UMP catabolic process
ETA18_16655	COG2445	Protein of unknown function DUF86
ETA18_16660	COG4470	Protein conserved in bacteria
ETA18_16670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ETA18_16675	COG0739	heme binding
ETA18_16685	COG3377	Domain of unknown function (DUF1805)
ETA18_16690	COG0737	Belongs to the 5'-nucleotidase family
ETA18_16695	COG0730	response to heat
ETA18_16700	COG1801	Protein of unknown function DUF72
ETA18_16710	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETA18_16715	COG2508	Transcriptional regulator
ETA18_16720	COG2233	PERMEase
ETA18_16725	COG2233	PERMEase
ETA18_16730	COG3195	allantoin biosynthetic process
ETA18_16730	COG3648	Uricase
ETA18_16735	COG2351	hydroxyisourate hydrolase activity
ETA18_16745	COG2080	2 iron, 2 sulfur cluster binding
ETA18_16750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ETA18_16755	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ETA18_16760	COG2068	MobA-Related Protein
ETA18_16765	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ETA18_16770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ETA18_16775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETA18_16785	COG2356	endonuclease I
ETA18_16800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA18_16805	COG3842	ATPase activity
ETA18_16810	COG2188	Transcriptional regulator
ETA18_16815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETA18_16820	COG0395	ABC-type sugar transport system, permease component
ETA18_16825	COG1175	transmembrane transport
ETA18_16830	COG1653	transport
ETA18_16835	COG2222	sugar isomerase
ETA18_16840	COG0322	excinuclease ABC activity
ETA18_16845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETA18_16860	COG0346	lactoylglutathione lyase activity
ETA18_16865	COG0640	Transcriptional regulator
ETA18_16880	COG3409	Peptidoglycan-binding domain 1 protein
ETA18_16880	COG1388	LysM domain
ETA18_16880	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETA18_16885	COG4824	toxin secretion phage lysis holin
ETA18_16925	COG5412	phage tail tape measure protein
ETA18_16925	COG3953	SLT domain
ETA18_17020	COG0582	viral genome integration into host DNA
ETA18_17100	COG3800	Transcriptional regulator
ETA18_17100	COG1396	sequence-specific DNA binding
ETA18_17120	COG0719	Fe-S assembly protein
ETA18_17125	COG0822	iron-sulfur transferase activity
ETA18_17130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETA18_17135	COG0719	Fe-S assembly protein
ETA18_17140	COG0396	ATPase activity
ETA18_17155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ETA18_17160	COG1464	Belongs to the NlpA lipoprotein family
ETA18_17165	COG2011	ABC-type metal ion transport system permease component
ETA18_17170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ETA18_17180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA18_17185	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ETA18_17195	COG0509	glycine decarboxylation via glycine cleavage system
ETA18_17200	COG1393	Belongs to the ArsC family
ETA18_17205	COG1960	acyl-CoA dehydrogenase activity
ETA18_17210	COG0183	Belongs to the thiolase family
ETA18_17215	COG1024	Enoyl-CoA hydratase
ETA18_17215	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETA18_17225	COG0506	proline dehydrogenase activity
ETA18_17235	COG5577	PFAM Coat F domain
ETA18_17240	COG1846	Transcriptional regulator
ETA18_17250	COG1942	4-Oxalocrotonate Tautomerase
ETA18_17255	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_17260	COG0583	DNA-binding transcription factor activity
ETA18_17270	COG1120	ATPase activity
ETA18_17285	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_17290	COG0783	Belongs to the Dps family
ETA18_17295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETA18_17300	COG0745	RESPONSE REGULATOR receiver
ETA18_17305	COG2205	protein histidine kinase activity
ETA18_17305	COG2770	Histidine kinase
ETA18_17315	COG1309	transcriptional regulator
ETA18_17320	COG0114	fumarate hydratase activity
ETA18_17330	COG0697	spore germination
ETA18_17335	COG0814	amino acid
ETA18_17345	COG2197	response regulator
ETA18_17350	COG4585	Histidine kinase
ETA18_17355	COG4758	membrane
ETA18_17360	COG3595	metallopeptidase activity
ETA18_17365	COG1842	Phage shock protein A
ETA18_17370	COG4758	membrane
ETA18_17375	COG2814	Major facilitator Superfamily
ETA18_17380	COG2096	Adenosyltransferase
ETA18_17385	COG1120	ATPase activity
ETA18_17390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA18_17395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA18_17400	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_17405	COG3386	PFAM SMP-30 Gluconolaconase
ETA18_17410	COG2205	protein histidine kinase activity
ETA18_17415	COG0745	RESPONSE REGULATOR receiver
ETA18_17425	COG1191	sigma factor activity
ETA18_17435	COG2140	Oxalate decarboxylase
ETA18_17445	COG0577	efflux transmembrane transporter activity
ETA18_17450	COG1136	(ABC) transporter
ETA18_17455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETA18_17460	COG1120	ATPase activity
ETA18_17465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA18_17470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA18_17475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA18_17480	COG0531	amino acid
ETA18_17495	COG1988	membrane-bound metal-dependent
ETA18_17500	COG1368	sulfuric ester hydrolase activity
ETA18_17505	COG1910	domain protein
ETA18_17510	COG0725	ABC transporter, periplasmic molybdate-binding protein
ETA18_17515	COG4149	molybdate abc transporter
ETA18_17520	COG0656	L-ascorbic acid biosynthetic process
ETA18_17530	COG0025	NhaP-type Na H and K H
ETA18_17535	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETA18_17540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETA18_17545	COG3973	AAA domain
ETA18_17550	COG2860	membrane
ETA18_17555	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ETA18_17560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ETA18_17565	COG2217	Heavy metal translocating P-type atpase
ETA18_17570	COG2217	Heavy metal translocating P-type atpase
ETA18_17575	COG2608	mercury ion transmembrane transporter activity
ETA18_17580	COG1937	Protein conserved in bacteria
ETA18_17585	COG0673	inositol 2-dehydrogenase activity
ETA18_17590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ETA18_17595	COG1289	transmembrane transporter activity
ETA18_17605	COG2076	Multidrug Resistance protein
ETA18_17610	COG1309	transcriptional regulator
ETA18_17615	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_17625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ETA18_17630	COG0557	exoribonuclease II activity
ETA18_17635	COG1647	Serine aminopeptidase, S33
ETA18_17640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ETA18_17645	COG0596	Alpha beta hydrolase
ETA18_17650	COG1476	TRANSCRIPTIONal
ETA18_17655	COG1396	sequence-specific DNA binding
ETA18_17660	COG1396	sequence-specific DNA binding
ETA18_17665	COG1733	regulation of RNA biosynthetic process
ETA18_17670	COG0840	transmembrane signaling receptor activity
ETA18_17675	COG1174	glycine betaine transport
ETA18_17680	COG1732	Glycine betaine
ETA18_17685	COG1174	glycine betaine transport
ETA18_17690	COG1125	glycine betaine transport
ETA18_17690	COG0517	IMP dehydrogenase activity
ETA18_17695	COG1510	regulation of RNA biosynthetic process
ETA18_17700	COG1174	glycine betaine transport
ETA18_17705	COG1732	Glycine betaine
ETA18_17710	COG1174	glycine betaine transport
ETA18_17715	COG0517	IMP dehydrogenase activity
ETA18_17715	COG1125	glycine betaine transport
ETA18_17720	COG1510	regulation of RNA biosynthetic process
ETA18_17725	COG2095	MarC family integral membrane protein
ETA18_17735	COG3064	Membrane
ETA18_17740	COG4640	response to antibiotic
ETA18_17745	COG0456	acetyltransferase
ETA18_17750	COG0148	phosphopyruvate hydratase activity
ETA18_17755	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ETA18_17760	COG0149	triose-phosphate isomerase activity
ETA18_17765	COG0126	phosphoglycerate kinase activity
ETA18_17770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETA18_17775	COG2390	Transcriptional regulator
ETA18_17780	COG2814	Major facilitator Superfamily
ETA18_17785	COG1609	Transcriptional regulator
ETA18_17790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETA18_17800	COG0583	DNA-binding transcription factor activity
ETA18_17805	COG0697	spore germination
ETA18_17810	COG1113	amino acid transport
ETA18_17815	COG3858	chitin binding
ETA18_17820	COG1556	Lactate utilization protein
ETA18_17825	COG1139	Iron-sulfur cluster binding protein
ETA18_17830	COG0247	lactate metabolic process
ETA18_17835	COG2197	response regulator
ETA18_17840	COG4585	Histidine kinase
ETA18_17845	COG0842	Transport permease protein
ETA18_17850	COG1131	(ABC) transporter
ETA18_17855	COG0596	Alpha beta hydrolase
ETA18_17860	COG2208	phosphoserine phosphatase activity
ETA18_17865	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ETA18_17870	COG1874	Beta-galactosidase
ETA18_17875	COG3833	ABC-type maltose transport systems, permease component
ETA18_17880	COG1175	transmembrane transport
ETA18_17885	COG2182	Extracellular solute-binding protein
ETA18_17890	COG1609	Transcriptional regulator
ETA18_17895	COG2186	Transcriptional regulator
ETA18_17900	COG1620	l-lactate permease
ETA18_17905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ETA18_17915	COG5039	Polysaccharide pyruvyl transferase
ETA18_17920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETA18_17925	COG0110	maltose O-acetyltransferase activity
ETA18_17930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ETA18_17935	COG2244	polysaccharide biosynthetic process
ETA18_17940	COG1216	Glycosyl transferase, family 2
ETA18_17945	COG5039	Polysaccharide pyruvyl transferase
ETA18_17950	COG1216	Glycosyl transferase, family 2
ETA18_17960	COG0438	transferase activity, transferring glycosyl groups
ETA18_17965	COG1215	transferase activity, transferring glycosyl groups
ETA18_17970	COG0438	transferase activity, transferring glycosyl groups
ETA18_17975	COG1086	Polysaccharide biosynthesis protein
ETA18_17980	COG0489	protein tyrosine kinase activity
ETA18_17985	COG3944	biosynthesis protein
ETA18_17990	COG1396	sequence-specific DNA binding
ETA18_17995	COG2272	Belongs to the type-B carboxylesterase lipase family
ETA18_18005	COG3479	Phenolic acid decarboxylase
ETA18_18015	COG1794	racemase activity, acting on amino acids and derivatives
ETA18_18020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETA18_18025	COG1621	beta-fructofuranosidase activity
ETA18_18030	COG1621	beta-fructofuranosidase activity
ETA18_18035	COG0531	amino acid
ETA18_18040	COG1309	transcriptional regulator
ETA18_18045	COG2076	Multidrug Resistance protein
ETA18_18050	COG2076	Multidrug Resistance protein
ETA18_18060	COG0277	FAD linked oxidase domain protein
ETA18_18065	COG3621	Patatin-like phospholipase
ETA18_18075	COG0740	serine-type endopeptidase activity
ETA18_18080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETA18_18085	COG0366	Alpha amylase catalytic
ETA18_18090	COG1554	hydrolase, family 65, central catalytic
ETA18_18095	COG5521	maltodextrose utilization protein MalA
ETA18_18100	COG3833	ABC-type maltose transport systems, permease component
ETA18_18105	COG1175	transmembrane transport
ETA18_18110	COG2182	Extracellular solute-binding protein
ETA18_18120	COG1609	Transcriptional regulator
ETA18_18125	COG1611	Belongs to the LOG family
ETA18_18130	COG1694	Mazg nucleotide pyrophosphohydrolase
ETA18_18135	COG0659	secondary active sulfate transmembrane transporter activity
ETA18_18140	COG0288	reversible hydration of carbon dioxide
ETA18_18145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETA18_18150	COG0577	efflux transmembrane transporter activity
ETA18_18155	COG1136	(ABC) transporter
ETA18_18160	COG5002	protein histidine kinase activity
ETA18_18165	COG0745	RESPONSE REGULATOR receiver
ETA18_18175	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ETA18_18180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA18_18185	COG1481	regulation of sporulation
ETA18_18190	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ETA18_18195	COG1660	Displays ATPase and GTPase activities
ETA18_18200	COG1051	belongs to the nudix hydrolase family
ETA18_18205	COG0492	ferredoxin-NADP+ reductase activity
ETA18_18210	COG3883	PFAM NLP P60 protein
ETA18_18210	COG0791	NLP P60 protein
ETA18_18215	COG0457	Tetratricopeptide repeat
ETA18_18220	COG1132	(ABC) transporter
ETA18_18245	COG0140	phosphoribosyl-ATP diphosphatase activity
ETA18_18245	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ETA18_18250	COG0107	imidazoleglycerol-phosphate synthase activity
ETA18_18255	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ETA18_18260	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ETA18_18265	COG0131	Imidazoleglycerol-phosphate dehydratase
ETA18_18270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ETA18_18275	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ETA18_18280	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ETA18_18285	COG4990	cell redox homeostasis
ETA18_18290	COG5297	Belongs to the glycosyl hydrolase family 6
ETA18_18295	COG0110	maltose O-acetyltransferase activity
ETA18_18300	COG0546	phosphoglycolate phosphatase activity
ETA18_18305	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ETA18_18310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ETA18_18315	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ETA18_18320	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ETA18_18325	COG0363	glucosamine-6-phosphate deaminase activity
ETA18_18335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ETA18_18340	COG1950	PFAM Membrane protein of
ETA18_18345	COG1983	PspC domain protein
ETA18_18350	COG3595	metallopeptidase activity
ETA18_18365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETA18_18370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETA18_18375	COG0556	nucleotide-excision repair
ETA18_18380	COG4897	Protein conserved in bacteria
ETA18_18385	COG0574	Belongs to the PEP-utilizing enzyme family
ETA18_18385	COG3848	Pyruvate phosphate dikinase
ETA18_18390	COG1309	transcriptional regulator
ETA18_18395	COG2814	Major facilitator Superfamily
ETA18_18400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETA18_18410	COG3409	Peptidoglycan-binding domain 1 protein
ETA18_18410	COG0793	Belongs to the peptidase S41A family
ETA18_18415	COG2177	Part of the ABC transporter FtsEX involved in
ETA18_18420	COG2884	Cell division ATP-binding protein ftsE
ETA18_18425	COG2010	Cytochrome c
ETA18_18430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA18_18440	COG0653	protein targeting
ETA18_18445	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ETA18_18460	COG1516	flagellar protein fliS
ETA18_18465	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ETA18_18470	COG1334	flagellar protein FlaG
ETA18_18475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETA18_18480	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETA18_18485	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ETA18_18495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETA18_18500	COG1256	bacterial-type flagellum assembly
ETA18_18500	COG4786	Flagellar basal body rod
ETA18_18505	COG3418	PFAM FlgN family protein
ETA18_18510	COG2747	anti-sigma28 factor FlgM
ETA18_18520	COG1040	competence protein
ETA18_18530	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ETA18_18535	COG1307	EDD domain protein, DegV family
ETA18_18540	COG2197	response regulator
ETA18_18545	COG4585	Histidine kinase
ETA18_18550	COG1739	Uncharacterized protein family UPF0029
ETA18_18555	COG1316	TRANSCRIPTIONal
ETA18_18590	COG1131	(ABC) transporter
ETA18_18600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETA18_18605	COG0438	transferase activity, transferring glycosyl groups
ETA18_18610	COG1215	transferase activity, transferring glycosyl groups
ETA18_18615	COG3206	protein involved in exopolysaccharide biosynthesis
ETA18_18620	COG3307	-O-antigen
ETA18_18630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETA18_18635	COG0297	glycogen (starch) synthase activity
ETA18_18635	COG0438	transferase activity, transferring glycosyl groups
ETA18_18640	COG2244	polysaccharide biosynthetic process
ETA18_18650	COG2247	cell wall binding repeat
ETA18_18650	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA18_18655	COG2385	sporulation resulting in formation of a cellular spore
ETA18_18655	COG2247	cell wall binding repeat
ETA18_18670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ETA18_18675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETA18_18685	COG1134	teichoic acid transport
ETA18_18690	COG1682	transport, permease protein
ETA18_18705	COG0463	Glycosyl transferase, family 2
ETA18_18705	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETA18_18710	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETA18_18715	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ETA18_18720	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ETA18_18725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETA18_18730	COG4193	domain, Protein
ETA18_18735	COG1482	cell wall glycoprotein biosynthetic process
ETA18_18740	COG0697	spore germination
ETA18_18745	COG0814	amino acid
ETA18_18755	COG2814	Major facilitator Superfamily
ETA18_18760	COG1316	TRANSCRIPTIONal
ETA18_18765	COG0561	phosphatase activity
ETA18_18770	COG0791	NLP P60 protein
ETA18_18780	COG2843	Capsule synthesis protein
ETA18_18790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ETA18_18795	COG1609	Transcriptional regulator
ETA18_18800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETA18_18805	COG1869	D-ribose catabolic process
ETA18_18810	COG1129	ABC transporter
ETA18_18815	COG1172	Belongs to the binding-protein-dependent transport system permease family
ETA18_18820	COG1879	ABC-type sugar transport system periplasmic component
ETA18_18825	COG3103	Sh3 type 3 domain protein
ETA18_18835	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETA18_18840	COG3527	Alpha-acetolactate decarboxylase
ETA18_18845	COG0028	Belongs to the TPP enzyme family
ETA18_18850	COG0583	DNA-binding transcription factor activity
ETA18_18855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ETA18_18870	COG5337	Spore coat protein CotH
ETA18_18880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETA18_18890	COG0405	Gamma-glutamyltransferase
ETA18_18895	COG1522	sequence-specific DNA binding
ETA18_18900	COG2059	Chromate
ETA18_18905	COG2059	Chromate
ETA18_18915	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETA18_18920	COG0583	DNA-binding transcription factor activity
ETA18_18970	COG5444	nuclease activity
ETA18_18995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETA18_19000	COG4464	protein tyrosine phosphatase activity
ETA18_19005	COG0489	protein tyrosine kinase activity
ETA18_19010	COG3944	biosynthesis protein
ETA18_19020	COG4715	Zinc finger, swim domain protein
ETA18_19025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETA18_19035	COG0561	phosphatase activity
ETA18_19040	COG1349	DNA-binding transcription factor activity
ETA18_19045	COG0629	single-stranded DNA binding
ETA18_19060	COG3764	Sortase (surface protein transpeptidase)
ETA18_19065	COG0745	RESPONSE REGULATOR receiver
ETA18_19065	COG2972	Histidine kinase
ETA18_19070	COG1970	mechanosensitive ion channel activity
ETA18_19075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETA18_19080	COG0457	Tetratricopeptide repeat
ETA18_19085	COG4786	Flagellar basal body rod
ETA18_19090	COG4786	Flagellar basal body rod
ETA18_19095	COG1077	Cell shape determining protein MreB Mrl
ETA18_19100	COG1609	Transcriptional regulator
ETA18_19110	COG1846	Transcriptional regulator
ETA18_19115	COG2814	Major facilitator Superfamily
ETA18_19120	COG3420	alginic acid biosynthetic process
ETA18_19125	COG1953	Uracil, thiamine, allantoin
ETA18_19130	COG0477	Major facilitator Superfamily
ETA18_19135	COG1335	isochorismatase
ETA18_19145	COG0004	ammonium transporteR
ETA18_19150	COG0347	Belongs to the P(II) protein family
ETA18_19155	COG0671	phosphoesterase, PA-phosphatase related
ETA18_19165	COG0739	heme binding
ETA18_19170	COG1247	-acetyltransferase
ETA18_19190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETA18_19195	COG0789	Transcriptional regulator
ETA18_19210	COG1959	2 iron, 2 sulfur cluster binding
ETA18_19215	COG0804	urea catabolic process
ETA18_19220	COG0832	Belongs to the urease beta subunit family
ETA18_19225	COG0831	urea catabolic process
ETA18_19240	COG3237	CsbD-like
ETA18_19245	COG1994	Peptidase M50
ETA18_19250	COG0457	Tetratricopeptide repeat
ETA18_19255	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ETA18_19260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ETA18_19270	COG2304	oxidoreductase activity
ETA18_19280	COG2304	oxidoreductase activity
ETA18_19285	COG2385	sporulation resulting in formation of a cellular spore
ETA18_19290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ETA18_19300	COG4836	Membrane
ETA18_19310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ETA18_19315	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ETA18_19320	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ETA18_19325	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ETA18_19330	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETA18_19335	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ETA18_19340	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETA18_19345	COG0356	it plays a direct role in the translocation of protons across the membrane
ETA18_19355	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ETA18_19360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ETA18_19365	COG4475	Protein of unknown function (DUF436)
ETA18_19370	COG0698	ribose 5-phosphate isomerase
ETA18_19375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETA18_19380	COG1971	Probably functions as a manganese efflux pump
ETA18_19385	COG0009	L-threonylcarbamoyladenylate synthase
ETA18_19390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ETA18_19410	COG2890	protein-(glutamine-N5) methyltransferase activity
ETA18_19415	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETA18_19420	COG0346	lactoylglutathione lyase activity
ETA18_19425	COG0789	Transcriptional regulator
ETA18_19430	COG0679	Auxin Efflux Carrier
ETA18_19435	COG0281	malic enzyme
ETA18_19440	COG1435	thymidine kinase activity
ETA18_19445	COG0254	rRNA binding
ETA18_19450	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETA18_19460	COG1494	fructose-1,6-bisphosphatase
ETA18_19465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ETA18_19470	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ETA18_19475	COG0191	fructose-bisphosphate aldolase activity
ETA18_19480	COG2204	response regulator
ETA18_19485	COG4821	SIS domain
ETA18_19490	COG0504	CTP synthase activity
ETA18_19495	COG3343	RNA polymerase activity
ETA18_19500	COG1960	acyl-CoA dehydrogenase activity
ETA18_19505	COG2181	nitrate reductase activity
ETA18_19505	COG0247	lactate metabolic process
ETA18_19510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETA18_19515	COG4294	response to UV
ETA18_19525	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETA18_19530	COG1132	(ABC) transporter
ETA18_19535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETA18_19545	COG2181	nitrate reductase activity
ETA18_19550	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ETA18_19555	COG1140	nitrate reductase beta subunit
ETA18_19560	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ETA18_19565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETA18_19575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETA18_19580	COG2223	nitrite transmembrane transporter activity
ETA18_19585	COG0018	arginyl-trna synthetase
ETA18_19590	COG4506	Protein conserved in bacteria
ETA18_19605	COG0535	radical SAM domain protein
ETA18_19615	COG1131	(ABC) transporter
ETA18_19620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETA18_19625	COG0612	Peptidase, M16
ETA18_19630	COG0612	Peptidase, M16
ETA18_19640	COG3391	amine dehydrogenase activity
ETA18_19645	COG3391	amine dehydrogenase activity
ETA18_19655	COG0457	Tetratricopeptide repeat
ETA18_19670	COG0010	Belongs to the arginase family
ETA18_19675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETA18_19680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETA18_19695	COG1994	Peptidase M50
ETA18_19700	COG1942	4-Oxalocrotonate Tautomerase
ETA18_19705	COG1846	Transcriptional regulator
ETA18_19710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETA18_19720	COG0477	Major facilitator Superfamily
ETA18_19725	COG1959	2 iron, 2 sulfur cluster binding
ETA18_19730	COG3465	dGTPase activity
ETA18_19735	COG1078	dGTPase activity
ETA18_19740	COG4844	belongs to the
ETA18_19750	COG0697	spore germination
ETA18_19755	COG0095	Lipoate-protein ligase
ETA18_19760	COG0583	DNA-binding transcription factor activity
ETA18_19765	COG0280	phosphate acetyltransferase
ETA18_19775	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_19780	COG0436	Aminotransferase
ETA18_19785	COG2814	Major facilitator Superfamily
ETA18_19790	COG0151	Belongs to the GarS family
ETA18_19795	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_19800	COG1917	Cupin 2, conserved barrel domain protein
ETA18_19805	COG0077	Prephenate dehydratase
ETA18_19810	COG2814	Major facilitator Superfamily
ETA18_19815	COG0833	amino acid
ETA18_19820	COG4187	Peptidase family M20/M25/M40
ETA18_19825	COG1012	belongs to the aldehyde dehydrogenase family
ETA18_19830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETA18_19840	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ETA18_19845	COG1091	dTDP-4-dehydrorhamnose reductase activity
ETA18_19850	COG1088	dTDP-glucose 4,6-dehydratase activity
ETA18_19855	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ETA18_19860	COG3980	spore coat polysaccharide biosynthesis protein
ETA18_19865	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
ETA18_19870	COG2089	acid synthase
ETA18_19875	COG0456	acetyltransferase
ETA18_19880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETA18_19885	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETA18_19890	COG0463	Glycosyl transferase, family 2
ETA18_19905	COG2363	Small membrane protein
ETA18_19910	COG2233	PERMEase
ETA18_19920	COG1012	belongs to the aldehyde dehydrogenase family
ETA18_19925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ETA18_19930	COG1216	Glycosyl transferase, family 2
ETA18_19935	COG0351	phosphomethylpyrimidine kinase
ETA18_19945	COG1621	beta-fructofuranosidase activity
ETA18_19950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_19950	COG1263	PTS System
ETA18_19955	COG2116	formate transmembrane transporter activity
ETA18_19960	COG3711	transcriptional antiterminator
ETA18_19970	COG1404	Belongs to the peptidase S8 family
ETA18_19975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETA18_19980	COG0778	Nitroreductase
ETA18_19985	COG0772	Belongs to the SEDS family
ETA18_20000	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ETA18_20005	COG1845	cytochrome c oxidase, subunit III
ETA18_20010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETA18_20015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETA18_20020	COG2261	transglycosylase associated protein
ETA18_20025	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ETA18_20030	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ETA18_20035	COG2246	polysaccharide biosynthetic process
ETA18_20040	COG1309	transcriptional regulator
ETA18_20050	COG3162	membrane
ETA18_20055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETA18_20060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ETA18_20065	COG2837	iron assimilation
ETA18_20070	COG2822	iron ion transport
ETA18_20075	COG0672	)-iron permease
ETA18_20080	COG0352	thiamine-phosphate diphosphorylase activity
ETA18_20085	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ETA18_20090	COG0583	DNA-binding transcription factor activity
ETA18_20095	COG1380	Effector of murein hydrolase LrgA
ETA18_20100	COG1346	cytolysis
ETA18_20105	COG2814	Major facilitator Superfamily
ETA18_20110	COG4895	conserved protein (DUF2196)
ETA18_20115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETA18_20120	COG0346	lactoylglutathione lyase activity
ETA18_20125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA18_20130	COG1404	Belongs to the peptidase S8 family
ETA18_20135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_20135	COG1263	PTS System
ETA18_20140	COG3711	transcriptional antiterminator
ETA18_20145	COG1442	glycosyl transferase family 8
ETA18_20150	COG5522	Integral membrane protein (intg_mem_TP0381)
ETA18_20155	COG1846	Transcriptional regulator
ETA18_20160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETA18_20165	COG2234	aminopeptidase activity
ETA18_20180	COG2814	Major facilitator Superfamily
ETA18_20185	COG2357	RelA SpoT domain protein
ETA18_20190	COG1575	Belongs to the MenA family. Type 1 subfamily
ETA18_20210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA18_20215	COG1696	Membrane protein involved in D-alanine export
ETA18_20220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETA18_20225	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ETA18_20230	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ETA18_20235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETA18_20240	COG1486	melibiose metabolic process
ETA18_20245	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETA18_20250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA18_20255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA18_20260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA18_20260	COG3711	transcriptional antiterminator
ETA18_20270	COG2094	Belongs to the DNA glycosylase MPG family
ETA18_20275	COG0753	catalase activity
ETA18_20280	COG2814	Major facilitator Superfamily
ETA18_20285	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETA18_20290	COG1131	(ABC) transporter
ETA18_20310	COG1595	DNA-templated transcription, initiation
ETA18_20315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ETA18_20320	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ETA18_20325	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ETA18_20330	COG4988	ABC transporter
ETA18_20335	COG1294	oxidase, subunit
ETA18_20340	COG1271	oxidase subunit
ETA18_20345	COG3493	citrate carrier protein
ETA18_20350	COG0501	Belongs to the peptidase M48B family
ETA18_20360	COG0726	polysaccharide deacetylase
ETA18_20365	COG3842	ATPase activity
ETA18_20370	COG2508	Transcriptional regulator
ETA18_20375	COG1012	belongs to the aldehyde dehydrogenase family
ETA18_20380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA18_20385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETA18_20395	COG4585	Histidine kinase
ETA18_20400	COG2197	response regulator
ETA18_20405	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETA18_20415	COG4894	glucomannan catabolic process
ETA18_20420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETA18_20425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETA18_20430	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_20435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ETA18_20440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETA18_20445	COG2610	gluconate transmembrane transporter activity
ETA18_20450	COG0500	methyltransferase
ETA18_20455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETA18_20470	COG0693	protein deglycase activity
ETA18_20470	COG0753	catalase activity
ETA18_20475	COG2851	Citrate transporter
ETA18_20480	COG2273	Hydrolase Family 16
ETA18_20485	COG3711	transcriptional antiterminator
ETA18_20495	COG2270	Major facilitator Superfamily
ETA18_20500	COG0513	Belongs to the DEAD box helicase family
ETA18_20505	COG2755	lipolytic protein G-D-S-L family
ETA18_20505	COG3401	FG-GAP repeat protein
ETA18_20615	COG3209	COG3209 Rhs family protein
ETA18_20630	COG0589	response to stress
ETA18_20635	COG2723	6-phospho-beta-galactosidase activity
ETA18_20640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_20640	COG1263	PTS System
ETA18_20640	COG2190	(PTS) system
ETA18_20650	COG5444	nuclease activity
ETA18_20675	COG0494	nUDIX hydrolase
ETA18_20680	COG3507	Belongs to the glycosyl hydrolase 43 family
ETA18_20695	COG2986	histidine ammonia-lyase
ETA18_20700	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ETA18_20705	COG1228	amidohydrolase
ETA18_20710	COG0010	Belongs to the arginase family
ETA18_20715	COG0833	amino acid
ETA18_20720	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ETA18_20725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETA18_20730	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ETA18_20735	COG2390	Transcriptional regulator
ETA18_20745	COG3192	ethanolamine utilization protein
ETA18_20750	COG2079	MmgE PrpD family protein
ETA18_20760	COG1126	abc transporter atp-binding protein
ETA18_20765	COG0765	amino acid transport
ETA18_20770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETA18_20785	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ETA18_20790	COG0561	phosphatase activity
ETA18_20820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA18_20825	COG5294	Protein conserved in bacteria
ETA18_20830	COG0577	efflux transmembrane transporter activity
ETA18_20835	COG1136	(ABC) transporter
ETA18_20840	COG2205	protein histidine kinase activity
ETA18_20845	COG0745	RESPONSE REGULATOR receiver
ETA18_20850	COG0191	fructose-bisphosphate aldolase activity
ETA18_20855	COG1082	Xylose isomerase domain protein TIM barrel
ETA18_20860	COG1082	Xylose isomerase domain protein TIM barrel
ETA18_20865	COG0673	inositol 2-dehydrogenase activity
ETA18_20870	COG2814	Major facilitator Superfamily
ETA18_20875	COG1082	Xylose isomerase domain protein TIM barrel
ETA18_20880	COG3962	Belongs to the TPP enzyme family
ETA18_20885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETA18_20895	COG1012	belongs to the aldehyde dehydrogenase family
ETA18_20900	COG1349	DNA-binding transcription factor activity
ETA18_20905	COG0667	Aldo Keto reductase
ETA18_20920	COG2814	Major facilitator Superfamily
ETA18_20925	COG0326	Molecular chaperone. Has ATPase activity
ETA18_20935	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_20940	COG1309	transcriptional regulator
ETA18_20945	COG1012	belongs to the aldehyde dehydrogenase family
ETA18_20950	COG0456	acetyltransferase
ETA18_20955	COG2850	peptidyl-arginine hydroxylation
ETA18_20960	COG2226	methyltransferase
ETA18_20975	COG0367	asparagine synthase
ETA18_20980	COG2814	Major facilitator Superfamily
ETA18_20985	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETA18_20995	COG1714	RDD family
ETA18_21000	COG2311	Membrane
ETA18_21005	COG1917	Cupin 2, conserved barrel domain protein
ETA18_21010	COG1309	transcriptional regulator
ETA18_21015	COG1028	Short-chain dehydrogenase reductase Sdr
ETA18_21020	COG1846	Transcriptional regulator
ETA18_21025	COG1380	Effector of murein hydrolase LrgA
ETA18_21030	COG1346	cytolysis
ETA18_21035	COG5039	Polysaccharide pyruvyl transferase
ETA18_21045	COG1802	Transcriptional regulator
ETA18_21050	COG1070	Carbohydrate kinase
ETA18_21055	COG2610	gluconate transmembrane transporter activity
ETA18_21060	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETA18_21065	COG0450	alkyl hydroperoxide reductase
ETA18_21070	COG3634	alkyl hydroperoxide reductase activity
ETA18_21075	COG2723	6-phospho-beta-galactosidase activity
ETA18_21080	COG2190	(PTS) system
ETA18_21085	COG2190	(PTS) system
ETA18_21085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA18_21085	COG1263	PTS System
ETA18_21090	COG2188	Transcriptional regulator
ETA18_21095	COG1074	ATP-dependent DNA helicase activity
ETA18_21100	COG0501	Belongs to the peptidase M48B family
ETA18_21125	COG1131	(ABC) transporter
ETA18_21130	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ETA18_21170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ETA18_21185	COG1063	alcohol dehydrogenase
ETA18_21205	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ETA18_21210	COG0456	acetyltransferase
ETA18_21215	COG0457	Tetratricopeptide repeat
ETA18_21225	COG0010	Belongs to the arginase family
ETA18_21230	COG0833	amino acid
ETA18_21235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETA18_21240	COG3829	transcription factor binding
ETA18_21245	COG5002	protein histidine kinase activity
ETA18_21270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETA18_21275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETA18_21280	COG4853	Protein conserved in bacteria
ETA18_21285	COG4863	YycH protein
ETA18_21290	COG5002	protein histidine kinase activity
ETA18_21295	COG0745	RESPONSE REGULATOR receiver
ETA18_21325	COG0346	lactoylglutathione lyase activity
ETA18_21330	COG0305	Participates in initiation and elongation during chromosome replication
ETA18_21345	COG3093	addiction module antidote protein HigA
ETA18_21350	COG2807	transmembrane transport
ETA18_21355	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETA18_21360	COG0359	binds to the 23S rRNA
ETA18_21365	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ETA18_21370	COG4241	membrane
ETA18_21380	COG5577	PFAM Coat F domain
ETA18_21385	COG1733	regulation of RNA biosynthetic process
ETA18_21390	COG1227	inorganic diphosphatase activity
ETA18_21400	COG2271	Major facilitator Superfamily
ETA18_21405	COG4978	Transcriptional regulator
ETA18_21405	COG0789	Transcriptional regulator
ETA18_21415	COG4319	ketosteroid isomerase
ETA18_21420	COG1357	PFAM Pentapeptide repeats (8 copies)
ETA18_21425	COG2814	Major facilitator Superfamily
ETA18_21430	COG0583	DNA-binding transcription factor activity
ETA18_21435	COG2153	protein acetylation
ETA18_21450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA18_21455	COG1846	Transcriptional regulator
ETA18_21460	COG2153	protein acetylation
ETA18_21465	COG2364	Membrane
ETA18_21470	COG0456	acetyltransferase
ETA18_21475	COG2315	Protein conserved in bacteria
ETA18_21480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETA18_21490	COG2814	Major facilitator Superfamily
ETA18_21500	COG1331	Highly conserved protein containing a thioredoxin domain
ETA18_21505	COG1266	CAAX protease self-immunity
ETA18_21510	COG2814	Major facilitator Superfamily
ETA18_21510	COG0477	Major facilitator Superfamily
ETA18_21515	COG0110	maltose O-acetyltransferase activity
ETA18_21520	COG0346	lactoylglutathione lyase activity
ETA18_21525	COG1609	Transcriptional regulator
ETA18_21530	COG0708	Exodeoxyribonuclease III
ETA18_21535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ETA18_21540	COG0629	single-stranded DNA binding
ETA18_21545	COG0360	Binds together with S18 to 16S ribosomal RNA
ETA18_21550	COG0012	GTP binding
ETA18_21555	COG0243	molybdopterin cofactor binding
ETA18_21560	COG4481	Protein conserved in bacteria
ETA18_21565	COG3949	Membrane
ETA18_21575	COG1475	DNA binding
ETA18_21580	COG1192	Involved in chromosome partitioning
ETA18_21590	COG1475	DNA binding
ETA18_21595	COG0357	Ribosomal RNA small subunit methyltransferase G
ETA18_21600	COG0445	tRNA wobble uridine modification
ETA18_21605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETA18_21610	COG1847	R3H domain protein
ETA18_21615	COG0706	membrane insertase activity
ETA18_21620	COG0594	ribonuclease P activity
ETA18_21625	COG0230	Belongs to the bacterial ribosomal protein bL34 family