locus-tag	class	description
NX819_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NX819_00010	COG0592	DNA-directed DNA polymerase activity
NX819_00015	COG2501	S4 domain
NX819_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NX819_00030	COG0187	DNA topoisomerase II activity
NX819_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NX819_00070	COG0516	GMP reductase activity
NX819_00070	COG0517	IMP dehydrogenase activity
NX819_00075	COG1686	Belongs to the peptidase S11 family
NX819_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NX819_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NX819_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NX819_00100	COG1428	Deoxynucleoside kinase
NX819_00105	COG1428	Deoxynucleoside kinase
NX819_00110	COG1388	LysM domain
NX819_00110	COG3858	chitin binding
NX819_00115	COG1335	isochorismatase
NX819_00120	COG0590	tRNA wobble adenosine to inosine editing
NX819_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NX819_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NX819_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NX819_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NX819_00190	COG3853	Toxic anion resistance protein (TelA)
NX819_00195	COG1982	Orn Lys Arg decarboxylase major
NX819_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NX819_00205	COG3870	Protein conserved in bacteria
NX819_00210	COG1728	Protein conserved in bacteria
NX819_00215	COG0470	DNA polymerase III
NX819_00220	COG1774	PSP1 C-terminal conserved region
NX819_00225	COG4467	Involved in initiation control of chromosome replication
NX819_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NX819_00235	COG2827	Endonuclease containing a URI domain
NX819_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NX819_00245	COG2002	toxin-antitoxin pair type II binding
NX819_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX819_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX819_00255	COG0084	hydrolase, TatD family'
NX819_00260	COG3583	domain protein
NX819_00260	COG3584	3D domain protein
NX819_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NX819_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NX819_00280	COG4466	Protein conserved in bacteria
NX819_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NX819_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NX819_00300	COG0251	oxidation-reduction process
NX819_00305	COG2088	sporulation resulting in formation of a cellular spore
NX819_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NX819_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NX819_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NX819_00325	COG0193	aminoacyl-tRNA hydrolase activity
NX819_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NX819_00340	COG2002	toxin-antitoxin pair type II binding
NX819_00345	COG2244	polysaccharide biosynthetic process
NX819_00350	COG3956	TIGRFAM MazG family protein
NX819_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NX819_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NX819_00375	COG1098	S1 RNA binding domain
NX819_00390	COG2208	phosphoserine phosphatase activity
NX819_00395	COG2304	oxidoreductase activity
NX819_00400	COG0515	serine threonine protein kinase
NX819_00405	COG0037	tRNA processing
NX819_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NX819_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NX819_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NX819_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NX819_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NX819_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NX819_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NX819_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
NX819_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX819_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NX819_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NX819_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NX819_00470	COG1396	sequence-specific DNA binding
NX819_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NX819_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NX819_00560	COG4463	regulation of RNA biosynthetic process
NX819_00565	COG3880	PFAM UvrB UvrC protein
NX819_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NX819_00575	COG0542	response to heat
NX819_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NX819_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NX819_00590	COG4956	integral membrane protein (PIN domain superfamily)
NX819_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NX819_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NX819_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NX819_00610	COG1045	serine acetyltransferase
NX819_00615	COG0215	cysteine-tRNA ligase activity
NX819_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NX819_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NX819_00630	COG3688	RNA-binding protein containing a PIN domain
NX819_00635	COG1595	DNA-templated transcription, initiation
NX819_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NX819_00650	COG0250	Participates in transcription elongation, termination and antitermination
NX819_00660	COG0081	regulation of translation
NX819_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NX819_00675	COG2813	Specifically methylates the guanine in position
NX819_00680	COG0085	RNA polymerase activity
NX819_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NX819_00690	COG1358	cellular component organization or biogenesis
NX819_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NX819_00700	COG0049	tRNA binding
NX819_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NX819_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NX819_00715	COG0596	Alpha beta hydrolase
NX819_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NX819_00730	COG0088	Forms part of the polypeptide exit tunnel
NX819_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NX819_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NX819_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NX819_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NX819_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NX819_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NX819_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NX819_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NX819_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NX819_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NX819_00820	COG0200	Binds to the 23S rRNA
NX819_00825	COG0201	protein transport
NX819_00830	COG0563	adenylate kinase activity
NX819_00835	COG0024	Methionine aminopeptidase
NX819_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
NX819_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NX819_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NX819_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NX819_00865	COG0202	RNA polymerase activity
NX819_00870	COG0203	ribosomal protein L17
NX819_00875	COG1122	ATPase activity
NX819_00880	COG1122	ATPase activity
NX819_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NX819_00890	COG0101	tRNA pseudouridine synthase activity
NX819_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NX819_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NX819_00905	COG2226	methyltransferase
NX819_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX819_00920	COG0489	protein tyrosine kinase activity
NX819_00930	COG2194	sulfuric ester hydrolase activity
NX819_00935	COG0726	polysaccharide deacetylase
NX819_00970	COG2856	Zn peptidase
NX819_00980	COG1395	domain, Protein
NX819_01045	COG0305	Participates in initiation and elongation during chromosome replication
NX819_01055	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NX819_01145	COG1783	phage Terminase large subunit
NX819_01150	COG5518	Phage portal protein
NX819_01155	COG2369	cell adhesion
NX819_01165	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NX819_01170	COG4653	Phage capsid family
NX819_01230	COG5280	Phage tail tape measure protein TP901
NX819_01230	COG3953	SLT domain
NX819_01235	COG1652	LysM domain
NX819_01240	COG4193	domain, Protein
NX819_01250	COG3628	GPW Gp25 family protein
NX819_01255	COG3299	homolog of phage Mu protein gp47
NX819_01260	COG3778	Protein conserved in bacteria
NX819_01305	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX819_01305	COG1388	LysM domain
NX819_01305	COG3409	Peptidoglycan-binding domain 1 protein
NX819_01315	COG5444	nuclease activity
NX819_01320	COG0457	Tetratricopeptide repeat
NX819_01335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NX819_01395	COG0659	secondary active sulfate transmembrane transporter activity
NX819_01400	COG0385	Bile acid
NX819_01405	COG2819	hydrolase of the alpha beta superfamily
NX819_01410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX819_01415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX819_01420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX819_01425	COG2207	Transcriptional regulator
NX819_01425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX819_01430	COG3876	Protein conserved in bacteria
NX819_01435	COG1472	Belongs to the glycosyl hydrolase 3 family
NX819_01440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NX819_01445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_01445	COG1263	PTS System
NX819_01450	COG1737	Transcriptional regulator
NX819_01455	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NX819_01460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX819_01465	COG1683	Conserved Protein
NX819_01495	COG1595	DNA-templated transcription, initiation
NX819_01500	COG5662	AntiSigma factor
NX819_01505	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NX819_01510	COG4856	YbbR-like protein
NX819_01515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NX819_01520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NX819_01530	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NX819_01535	COG2169	Transcriptional regulator
NX819_01540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NX819_01545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NX819_01550	COG3002	Belongs to the UPF0753 family
NX819_01555	COG0288	reversible hydration of carbon dioxide
NX819_01565	COG5609	conserved protein (DUF2294)
NX819_01570	COG0640	Transcriptional regulator
NX819_01575	COG2814	Major facilitator Superfamily
NX819_01590	COG0535	radical SAM domain protein
NX819_01595	COG1266	CAAX protease self-immunity
NX819_01600	COG1131	(ABC) transporter
NX819_01610	COG1413	lyase activity
NX819_01615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX819_01620	COG0596	Alpha beta hydrolase
NX819_01625	COG0745	RESPONSE REGULATOR receiver
NX819_01630	COG0642	Histidine kinase
NX819_01640	COG0515	serine threonine protein kinase
NX819_01655	COG1113	amino acid transport
NX819_01670	COG2602	Beta-lactamase
NX819_01675	COG2124	cytochrome p450
NX819_01685	COG0531	amino acid
NX819_01690	COG0584	glycerophosphoryl diester phosphodiesterase
NX819_01695	COG2271	Major facilitator Superfamily
NX819_01705	COG1846	Transcriptional regulator
NX819_01705	COG0456	acetyltransferase
NX819_01710	COG2271	Major facilitator Superfamily
NX819_01720	COG3409	Peptidoglycan-binding domain 1 protein
NX819_01725	COG0697	spore germination
NX819_01730	COG1917	Cupin 2, conserved barrel domain protein
NX819_01730	COG2207	Transcriptional regulator
NX819_01735	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NX819_01740	COG3591	Belongs to the peptidase S1B family
NX819_01750	COG0596	Alpha beta hydrolase
NX819_01755	COG1183	phosphatidylcholine synthase activity
NX819_01760	COG0586	Pfam SNARE associated Golgi protein
NX819_01765	COG0688	phosphatidylethanolamine metabolic process
NX819_01775	COG2312	Erythromycin esterase
NX819_01780	COG2207	Transcriptional regulator
NX819_01785	COG1054	Belongs to the UPF0176 family
NX819_01790	COG1301	dicarboxylic acid transport
NX819_01795	COG2190	(PTS) system
NX819_01795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_01795	COG1263	PTS System
NX819_01800	COG0363	glucosamine-6-phosphate deaminase activity
NX819_01805	COG2188	Transcriptional regulator
NX819_01815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX819_01820	COG0833	amino acid
NX819_01825	COG2040	homocysteine
NX819_01830	COG1115	amino acid carrier protein
NX819_01835	COG2066	Belongs to the glutaminase family
NX819_01840	COG4191	Histidine kinase
NX819_01845	COG0784	Response regulator, receiver
NX819_01850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NX819_01855	COG1012	belongs to the aldehyde dehydrogenase family
NX819_01860	COG2271	Major facilitator Superfamily
NX819_01865	COG4948	Mandelate Racemase Muconate Lactonizing
NX819_01870	COG2186	Transcriptional regulator
NX819_01875	COG2721	sulfolactate sulfo-lyase activity
NX819_01880	COG3173	Aminoglycoside phosphotransferase
NX819_01890	COG0697	spore germination
NX819_01895	COG0745	RESPONSE REGULATOR receiver
NX819_01900	COG2205	protein histidine kinase activity
NX819_01905	COG1131	(ABC) transporter
NX819_01925	COG3773	Cell wall hydrolase
NX819_01930	COG2304	oxidoreductase activity
NX819_01940	COG3540	Alkaline phosphatase
NX819_01945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NX819_01950	COG0805	protein transport
NX819_01955	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NX819_01960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NX819_01965	COG0477	Major facilitator Superfamily
NX819_01970	COG1309	transcriptional regulator
NX819_01975	COG0252	asparaginase activity
NX819_01980	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NX819_01985	COG1714	RDD family
NX819_01990	COG3012	SEC-C Motif Domain Protein
NX819_01990	COG1405	negative regulation of cell septum assembly
NX819_01995	COG3290	protein histidine kinase activity
NX819_02000	COG3279	Response regulator of the LytR AlgR family
NX819_02005	COG4555	ABC transporter
NX819_02010	COG1668	transmembrane transport
NX819_02015	COG0667	Aldo Keto reductase
NX819_02030	COG1595	DNA-templated transcription, initiation
NX819_02035	COG1595	DNA-templated transcription, initiation
NX819_02040	COG1876	peptidase activity
NX819_02045	COG0457	Tetratricopeptide repeat
NX819_02050	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_02055	COG0366	Alpha amylase catalytic
NX819_02060	COG0803	Belongs to the bacterial solute-binding protein 9 family
NX819_02065	COG1121	(ABC) transporter
NX819_02070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NX819_02075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX819_02080	COG2310	stress, protein
NX819_02085	COG2310	stress, protein
NX819_02090	COG2310	stress, protein
NX819_02095	COG0861	Integral membrane protein TerC family
NX819_02105	COG3853	Toxic anion resistance protein (TelA)
NX819_02110	COG0477	Major facilitator Superfamily
NX819_02115	COG2814	Major facilitator Superfamily
NX819_02120	COG0640	Transcriptional regulator
NX819_02125	COG4175	Glycine betaine
NX819_02125	COG0517	IMP dehydrogenase activity
NX819_02130	COG4176	ABC-type proline glycine betaine transport system permease component
NX819_02135	COG2113	Glycine betaine
NX819_02140	COG1473	amidohydrolase
NX819_02145	COG1288	antiporter activity
NX819_02155	COG0366	Alpha amylase catalytic
NX819_02160	COG0039	L-malate dehydrogenase activity
NX819_02165	COG1620	l-lactate permease
NX819_02170	COG2814	Major facilitator Superfamily
NX819_02175	COG1846	Transcriptional regulator
NX819_02180	COG1280	lysine exporter protein (LysE YggA)
NX819_02185	COG3403	YqcI/YcgG family
NX819_02190	COG1113	amino acid transport
NX819_02195	COG3665	Urea carboxylase-associated protein
NX819_02200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NX819_02205	COG1660	Displays ATPase and GTPase activities
NX819_02210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NX819_02215	COG2226	methyltransferase
NX819_02220	COG0583	DNA-binding transcription factor activity
NX819_02225	COG3458	cephalosporin-C deacetylase activity
NX819_02230	COG3541	Predicted nucleotidyltransferase
NX819_02235	COG0506	proline dehydrogenase activity
NX819_02240	COG1012	belongs to the aldehyde dehydrogenase family
NX819_02245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX819_02250	COG2508	Transcriptional regulator
NX819_02255	COG3689	TIGRFAM TIGR03943 family protein
NX819_02260	COG0701	Predicted permease
NX819_02265	COG2267	carboxylic ester hydrolase activity
NX819_02270	COG0492	ferredoxin-NADP+ reductase activity
NX819_02275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NX819_02275	COG1587	Uroporphyrinogen-III synthase
NX819_02280	COG2146	nitrite reductase [NAD(P)H] activity
NX819_02285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NX819_02290	COG0243	molybdopterin cofactor binding
NX819_02295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NX819_02300	COG2223	nitrite transmembrane transporter activity
NX819_02305	COG1469	GTP cyclohydrolase I activity
NX819_02310	COG1376	ErfK ybiS ycfS ynhG family protein
NX819_02320	COG0523	cobalamin synthesis protein
NX819_02325	COG0765	amino acid transport
NX819_02330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX819_02350	COG2723	6-phospho-beta-galactosidase activity
NX819_02360	COG3209	COG3209 Rhs family protein
NX819_02365	COG3290	protein histidine kinase activity
NX819_02365	COG0840	transmembrane signaling receptor activity
NX819_02370	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NX819_02375	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NX819_02380	COG1733	regulation of RNA biosynthetic process
NX819_02385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_02405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_02410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_02415	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NX819_02420	COG2814	Major facilitator Superfamily
NX819_02430	COG0697	spore germination
NX819_02435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX819_02445	COG2364	Membrane
NX819_02450	COG1126	abc transporter atp-binding protein
NX819_02455	COG0765	amino acid transport
NX819_02460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX819_02465	COG0583	DNA-binding transcription factor activity
NX819_02470	COG0163	prenyltransferase activity
NX819_02475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NX819_02490	COG0596	Alpha beta hydrolase
NX819_02495	COG3104	oligopeptide transport
NX819_02500	COG5434	Belongs to the glycosyl hydrolase 28 family
NX819_02510	COG0697	spore germination
NX819_02520	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NX819_02525	COG1136	(ABC) transporter
NX819_02530	COG0577	efflux transmembrane transporter activity
NX819_02535	COG0745	RESPONSE REGULATOR receiver
NX819_02540	COG5002	protein histidine kinase activity
NX819_02540	COG3850	Histidine kinase
NX819_02545	COG0457	Tetratricopeptide repeat
NX819_02565	COG0527	aspartate kinase activity
NX819_02570	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX819_02575	COG4605	iron ion homeostasis
NX819_02580	COG4604	ABC transporter, ATP-binding protein
NX819_02585	COG4607	ABC-type enterochelin transport system periplasmic component
NX819_02590	COG2814	Major facilitator Superfamily
NX819_02595	COG1309	transcriptional regulator
NX819_02600	COG0778	Nitroreductase
NX819_02605	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NX819_02610	COG0640	Transcriptional regulator
NX819_02615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX819_02620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NX819_02625	COG1012	belongs to the aldehyde dehydrogenase family
NX819_02630	COG4975	Glucose uptake
NX819_02635	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_02640	COG4549	nuclear export factor GLE1
NX819_02645	COG2372	response to copper ion
NX819_02645	COG1276	copper resistance
NX819_02650	COG1349	DNA-binding transcription factor activity
NX819_02660	COG2213	PTS system mannitol-specific
NX819_02665	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX819_02670	COG0246	Mannitol dehydrogenase
NX819_02675	COG0473	3-isopropylmalate dehydrogenase activity
NX819_02680	COG0681	Belongs to the peptidase S26 family
NX819_02685	COG0412	Dienelactone hydrolase
NX819_02690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NX819_02700	COG0561	phosphatase activity
NX819_02705	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NX819_02710	COG1914	H( )-stimulated, divalent metal cation uptake system
NX819_02715	COG4336	lyase activity
NX819_02720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NX819_02725	COG1984	allophanate hydrolase subunit 2
NX819_02730	COG1414	Transcriptional regulator
NX819_02735	COG2755	lipolytic protein G-D-S-L family
NX819_02745	COG2329	Antibiotic biosynthesis monooxygenase
NX819_02750	COG0768	penicillin binding
NX819_02755	COG4989	oxidoreductase activity
NX819_02760	COG3711	transcriptional antiterminator
NX819_02765	COG0318	PFAM AMP-dependent synthetase and ligase
NX819_02770	COG2226	methyltransferase
NX819_02775	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_02780	COG1917	Cupin 2, conserved barrel domain protein
NX819_02785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX819_02790	COG3871	stress protein (general stress protein 26)
NX819_02800	COG2814	Major facilitator Superfamily
NX819_02805	COG1522	sequence-specific DNA binding
NX819_02810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NX819_02810	COG0551	DNA topoisomerase type I activity
NX819_02815	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NX819_02820	COG3706	GGDEF domain
NX819_02825	COG5298	Protein conserved in bacteria
NX819_02830	COG1215	transferase activity, transferring glycosyl groups
NX819_02840	COG0531	amino acid
NX819_02845	COG0494	nUDIX hydrolase
NX819_02850	COG0028	Belongs to the TPP enzyme family
NX819_02865	COG1914	H( )-stimulated, divalent metal cation uptake system
NX819_02870	COG2261	transglycosylase associated protein
NX819_02875	COG4876	unkown
NX819_02880	COG2217	Heavy metal translocating P-type atpase
NX819_02885	COG3729	General stress protein
NX819_02890	COG0662	Cupin 2, conserved barrel domain protein
NX819_02895	COG2329	Antibiotic biosynthesis monooxygenase
NX819_02900	COG3546	catalase activity
NX819_02905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NX819_02910	COG3290	protein histidine kinase activity
NX819_02915	COG4565	transcriptional regulatory protein
NX819_02920	COG1301	dicarboxylic acid transport
NX819_02925	COG0628	permease
NX819_02930	COG1131	(ABC) transporter
NX819_02935	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NX819_02945	COG1960	acyl-CoA dehydrogenase activity
NX819_02960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NX819_02965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX819_02970	COG1181	Belongs to the D-alanine--D-alanine ligase family
NX819_02975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NX819_02980	COG0513	Belongs to the DEAD box helicase family
NX819_02985	COG3402	PFAM membrane-flanked domain
NX819_02990	COG3428	Bacterial PH domain
NX819_02995	COG0705	Rhomboid family
NX819_03000	COG0736	holo-[acyl-carrier-protein] synthase activity
NX819_03005	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NX819_03010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NX819_03015	COG0864	Transcriptional regulator
NX819_03020	COG2337	Toxic component of a toxin-antitoxin (TA) module
NX819_03025	COG1366	Belongs to the anti-sigma-factor antagonist family
NX819_03030	COG1366	Belongs to the anti-sigma-factor antagonist family
NX819_03035	COG2172	sigma factor antagonist activity
NX819_03040	COG2208	phosphoserine phosphatase activity
NX819_03045	COG1366	Belongs to the anti-sigma-factor antagonist family
NX819_03050	COG2172	sigma factor antagonist activity
NX819_03055	COG1191	sigma factor activity
NX819_03060	COG2208	phosphoserine phosphatase activity
NX819_03080	COG1673	EVE domain
NX819_03085	COG1846	Transcriptional regulator
NX819_03090	COG2183	response to ionizing radiation
NX819_03100	COG3091	SprT-like family
NX819_03140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX819_03150	COG5444	nuclease activity
NX819_03155	COG1476	TRANSCRIPTIONal
NX819_03180	COG0693	protein deglycase activity
NX819_03185	COG1278	Cold shock
NX819_03190	COG1329	Transcriptional regulator
NX819_03195	COG0697	spore germination
NX819_03200	COG2207	Transcriptional regulator
NX819_03200	COG1917	Cupin 2, conserved barrel domain protein
NX819_03205	COG0697	spore germination
NX819_03210	COG3708	Transcriptional regulator
NX819_03210	COG2207	Transcriptional regulator
NX819_03215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX819_03220	COG0477	Major facilitator Superfamily
NX819_03230	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
NX819_03245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX819_03250	COG1309	transcriptional regulator
NX819_03255	COG0697	spore germination
NX819_03260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX819_03265	COG2030	dehydratase
NX819_03270	COG3545	Serine hydrolase
NX819_03275	COG1733	regulation of RNA biosynthetic process
NX819_03280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX819_03285	COG2814	Major facilitator Superfamily
NX819_03290	COG1309	transcriptional regulator
NX819_03295	COG0640	Transcriptional regulator
NX819_03300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NX819_03310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX819_03315	COG0697	spore germination
NX819_03320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX819_03325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NX819_03330	COG0640	Transcriptional regulator
NX819_03335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NX819_03350	COG4585	Histidine kinase
NX819_03355	COG2197	response regulator
NX819_03360	COG2409	Drug exporters of the RND superfamily
NX819_03365	COG0596	Alpha beta hydrolase
NX819_03370	COG1811	Na channel or pump
NX819_03375	COG4978	Transcriptional regulator
NX819_03375	COG0789	Transcriptional regulator
NX819_03380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NX819_03385	COG0778	Nitroreductase
NX819_03390	COG0346	lactoylglutathione lyase activity
NX819_03395	COG2259	Doxx family
NX819_03400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX819_03420	COG2323	membrane
NX819_03425	COG2323	membrane
NX819_03430	COG0071	Belongs to the small heat shock protein (HSP20) family
NX819_03445	COG1309	transcriptional regulator
NX819_03455	COG0456	acetyltransferase
NX819_03460	COG0488	(ABC) transporter
NX819_03465	COG1113	amino acid transport
NX819_03470	COG2318	DinB family
NX819_03475	COG1846	Transcriptional regulator
NX819_03480	COG1033	growth of symbiont in host cell
NX819_03480	COG2409	Drug exporters of the RND superfamily
NX819_03485	COG0778	Nitroreductase
NX819_03490	COG1846	Transcriptional regulator
NX819_03495	COG2814	Major facilitator Superfamily
NX819_03500	COG0730	response to heat
NX819_03505	COG1802	Transcriptional regulator
NX819_03510	COG3858	chitin binding
NX819_03510	COG1388	LysM domain
NX819_03515	COG1819	glycosyl
NX819_03525	COG1785	Belongs to the alkaline phosphatase family
NX819_03530	COG5646	InterPro IPR014922
NX819_03540	COG0454	-acetyltransferase
NX819_03545	COG1078	dGTPase activity
NX819_03550	COG1388	LysM domain
NX819_03555	COG2814	Major facilitator Superfamily
NX819_03560	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NX819_03565	COG1447	Phosphotransferase system cellobiose-specific component IIA
NX819_03570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NX819_03575	COG2723	6-phospho-beta-galactosidase activity
NX819_03580	COG2188	Transcriptional regulator
NX819_03585	COG1940	carbohydrate kinase activity
NX819_03590	COG1482	cell wall glycoprotein biosynthetic process
NX819_03595	COG4124	Belongs to the glycosyl hydrolase 26 family
NX819_03640	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NX819_03645	COG0802	atpase or kinase
NX819_03650	COG1214	PFAM Peptidase M22, glycoprotease
NX819_03655	COG0456	acetyltransferase
NX819_03660	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NX819_03665	COG0488	(ABC) transporter
NX819_03670	COG0315	cyclic pyranopterin monophosphate synthase activity
NX819_03675	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NX819_03680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NX819_03685	COG0805	protein transport
NX819_03695	COG1266	CAAX protease self-immunity
NX819_03705	COG0459	protein refolding
NX819_03715	COG1073	alpha beta
NX819_03720	COG0457	Tetratricopeptide repeat
NX819_03725	COG1063	alcohol dehydrogenase
NX819_03730	COG2211	Major facilitator Superfamily
NX819_03735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX819_03740	COG1842	Phage shock protein A
NX819_03745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NX819_03750	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NX819_03755	COG4260	virion core protein, lumpy skin disease virus
NX819_03765	COG2814	Major facilitator Superfamily
NX819_03770	COG1063	alcohol dehydrogenase
NX819_03775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NX819_03780	COG0823	Involved in the tonB-independent uptake of proteins
NX819_03795	COG2267	carboxylic ester hydrolase activity
NX819_03805	COG2132	Multicopper oxidase
NX819_03810	COG1113	amino acid transport
NX819_03820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NX819_03825	COG0714	Associated with various cellular activities
NX819_03830	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NX819_03835	COG1305	Transglutaminase-like
NX819_03840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NX819_03840	COG0519	Catalyzes the synthesis of GMP from XMP
NX819_03855	COG2252	PERMEase
NX819_03860	COG3064	Membrane
NX819_03870	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NX819_03880	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NX819_03885	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NX819_03890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NX819_03895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NX819_03900	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NX819_03905	COG0047	phosphoribosylformylglycinamidine synthase activity
NX819_03910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NX819_03915	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NX819_03920	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NX819_03925	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NX819_03930	COG0138	bifunctional purine biosynthesis protein purh
NX819_03935	COG0151	Belongs to the GarS family
NX819_03940	COG1522	sequence-specific DNA binding
NX819_03945	COG0531	amino acid
NX819_03955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NX819_03960	COG1470	cell adhesion involved in biofilm formation
NX819_03965	COG4496	protein, YerC YecD
NX819_03970	COG0069	glutamate synthase activity
NX819_03975	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NX819_03980	COG0210	DNA helicase
NX819_03985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NX819_03990	COG4851	CamS sex pheromone cAM373 precursor
NX819_03995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NX819_04000	COG1285	pathogenesis
NX819_04005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX819_04010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NX819_04015	COG0154	amidase activity
NX819_04020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NX819_04025	COG1309	transcriptional regulator
NX819_04030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NX819_04035	COG1597	lipid kinase activity
NX819_04040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NX819_04045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX819_04050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX819_04055	COG1002	Type II restriction enzyme, methylase subunits
NX819_04060	COG1061	Type III restriction enzyme res subunit
NX819_04065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NX819_04085	COG5444	nuclease activity
NX819_04090	COG3391	amine dehydrogenase activity
NX819_04095	COG0457	Tetratricopeptide repeat
NX819_04105	COG0217	transcriptional regulatory protein
NX819_04115	COG1309	transcriptional regulator
NX819_04120	COG3631	Ketosteroid isomerase-related protein
NX819_04140	COG3546	catalase activity
NX819_04145	COG0454	-acetyltransferase
NX819_04155	COG5578	integral membrane protein
NX819_04160	COG2972	Histidine kinase
NX819_04165	COG4753	response regulator
NX819_04165	COG2207	Transcriptional regulator
NX819_04170	COG1653	transport
NX819_04175	COG1175	transmembrane transport
NX819_04180	COG0395	ABC-type sugar transport system, permease component
NX819_04185	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NX819_04190	COG2207	Transcriptional regulator
NX819_04195	COG2755	lipolytic protein G-D-S-L family
NX819_04205	COG5578	integral membrane protein
NX819_04210	COG3401	FG-GAP repeat protein
NX819_04215	COG3401	FG-GAP repeat protein
NX819_04220	COG2755	lipolytic protein G-D-S-L family
NX819_04225	COG1874	Beta-galactosidase
NX819_04235	COG1653	transport
NX819_04240	COG4209	transmembrane transport
NX819_04245	COG0395	ABC-type sugar transport system, permease component
NX819_04250	COG1486	melibiose metabolic process
NX819_04255	COG2323	membrane
NX819_04260	COG2329	Antibiotic biosynthesis monooxygenase
NX819_04265	COG0346	lactoylglutathione lyase activity
NX819_04280	COG5583	Uncharacterized small protein (DUF2292)
NX819_04285	COG0670	Belongs to the BI1 family
NX819_04290	COG0697	spore germination
NX819_04295	COG1846	Transcriptional regulator
NX819_04300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX819_04315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX819_04315	COG2124	cytochrome p450
NX819_04320	COG1368	sulfuric ester hydrolase activity
NX819_04325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NX819_04330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX819_04335	COG1442	glycosyl transferase family 8
NX819_04340	COG1216	Glycosyl transferase, family 2
NX819_04345	COG1442	glycosyl transferase family 8
NX819_04350	COG2223	nitrite transmembrane transporter activity
NX819_04355	COG1011	Hydrolase
NX819_04360	COG0531	amino acid
NX819_04365	COG1012	belongs to the aldehyde dehydrogenase family
NX819_04370	COG0840	transmembrane signaling receptor activity
NX819_04375	COG0488	(ABC) transporter
NX819_04385	COG0789	Transcriptional regulator
NX819_04390	COG2814	Major facilitator Superfamily
NX819_04400	COG0488	(ABC) transporter
NX819_04405	COG0513	Belongs to the DEAD box helicase family
NX819_04410	COG0456	acetyltransferase
NX819_04415	COG2130	NADP-dependent
NX819_04420	COG2211	Major facilitator Superfamily
NX819_04425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NX819_04430	COG1120	ATPase activity
NX819_04435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX819_04440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX819_04445	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NX819_04460	COG3866	Pectate lyase
NX819_04465	COG0471	metal ion transport
NX819_04470	COG3290	protein histidine kinase activity
NX819_04475	COG4565	transcriptional regulatory protein
NX819_04480	COG3181	Tripartite tricarboxylate transporter family receptor
NX819_04490	COG2851	Citrate transporter
NX819_04495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX819_04500	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NX819_04505	COG1254	Belongs to the acylphosphatase family
NX819_04510	COG2258	MOSC domain
NX819_04530	COG0024	Methionine aminopeptidase
NX819_04535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_04535	COG1263	PTS System
NX819_04540	COG1368	sulfuric ester hydrolase activity
NX819_04555	COG1115	amino acid carrier protein
NX819_04560	COG0531	amino acid
NX819_04575	COG0697	spore germination
NX819_04580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_04580	COG1263	PTS System
NX819_04585	COG0366	Alpha amylase catalytic
NX819_04590	COG2188	Transcriptional regulator
NX819_04595	COG0778	Nitroreductase
NX819_04600	COG0737	Belongs to the 5'-nucleotidase family
NX819_04605	COG0693	protein deglycase activity
NX819_04610	COG2814	Major facilitator Superfamily
NX819_04615	COG4840	Belongs to the UPF0435 family
NX819_04620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NX819_04625	COG4980	gas vesicle protein
NX819_04630	COG1295	ribonuclease BN
NX819_04635	COG0477	Major facilitator Superfamily
NX819_04640	COG0387	Pfam Sodium calcium exchanger
NX819_04650	COG0668	transmembrane transport
NX819_04655	COG0535	radical SAM domain protein
NX819_04665	COG0726	polysaccharide deacetylase
NX819_04670	COG2084	Dehydrogenase
NX819_04675	COG0598	Magnesium transport protein CorA
NX819_04680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NX819_04685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NX819_04695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NX819_04700	COG4637	Psort location Cytoplasmic, score
NX819_04710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NX819_04715	COG0022	dehydrogenase e1 component
NX819_04720	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX819_04725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NX819_04730	COG3284	Transcriptional regulator
NX819_04740	COG1742	UPF0060 membrane protein
NX819_04765	COG4842	Belongs to the WXG100 family
NX819_04770	COG1486	melibiose metabolic process
NX819_04775	COG1737	Transcriptional regulator
NX819_04780	COG1263	PTS System
NX819_04780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_04785	COG1132	(ABC) transporter
NX819_04790	COG1132	(ABC) transporter
NX819_04795	COG2259	Doxx family
NX819_04800	COG2514	catechol 2,3-dioxygenase activity
NX819_04805	COG1917	Cupin 2, conserved barrel domain protein
NX819_04805	COG4977	sequence-specific DNA binding
NX819_04810	COG2814	Major facilitator Superfamily
NX819_04815	COG1082	Xylose isomerase domain protein TIM barrel
NX819_04820	COG0673	inositol 2-dehydrogenase activity
NX819_04825	COG4585	Histidine kinase
NX819_04830	COG2197	response regulator
NX819_04835	COG1131	(ABC) transporter
NX819_04840	COG0842	Transport permease protein
NX819_04840	COG1511	domain protein
NX819_04845	COG0842	Transport permease protein
NX819_04850	COG1695	Transcriptional regulator
NX819_04855	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NX819_04860	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NX819_04865	COG1309	transcriptional regulator
NX819_04870	COG2814	Major facilitator Superfamily
NX819_04875	COG2318	DinB family
NX819_04880	COG2814	Major facilitator Superfamily
NX819_04885	COG1846	Transcriptional regulator
NX819_04890	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NX819_04890	COG0392	lysyltransferase activity
NX819_04895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX819_04900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX819_04905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX819_04910	COG0384	phenazine biosynthesis protein PhzF
NX819_04915	COG0778	Nitroreductase
NX819_04930	COG1090	epimerase
NX819_04935	COG2137	regulation of response to DNA damage stimulus
NX819_04945	COG2814	Major facilitator Superfamily
NX819_04960	COG3103	Sh3 type 3 domain protein
NX819_04965	COG5658	integral membrane protein
NX819_04970	COG0596	Alpha beta hydrolase
NX819_04975	COG0463	Glycosyl transferase, family 2
NX819_04980	COG4485	Bacterial membrane protein, YfhO
NX819_04985	COG1988	membrane-bound metal-dependent
NX819_04990	COG1194	a g-specific adenine glycosylase
NX819_05000	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_05015	COG3557	Belongs to the UPF0374 family
NX819_05020	COG1132	(ABC) transporter
NX819_05025	COG4129	membrane
NX819_05030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NX819_05035	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NX819_05040	COG0735	belongs to the Fur family
NX819_05150	COG4326	sporulation control protein
NX819_05160	COG5577	PFAM Coat F domain
NX819_05165	COG3340	Belongs to the peptidase S51 family
NX819_05170	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NX819_05175	COG0277	FAD linked oxidase domain protein
NX819_05185	COG0753	catalase activity
NX819_05190	COG1116	anion transmembrane transporter activity
NX819_05195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NX819_05200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NX819_05205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX819_05215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NX819_05225	COG1476	TRANSCRIPTIONal
NX819_05235	COG3382	B3 4 domain protein
NX819_05240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NX819_05250	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NX819_05255	COG0789	Transcriptional regulator
NX819_05260	COG1664	Polymer-forming cytoskeletal
NX819_05265	COG1664	Polymer-forming cytoskeletal
NX819_05270	COG2766	serine protein kinase
NX819_05275	COG2718	Belongs to the UPF0229 family
NX819_05280	COG1846	Transcriptional regulator
NX819_05285	COG1566	PFAM secretion protein HlyD family protein
NX819_05290	COG2814	Major facilitator Superfamily
NX819_05295	COG0655	NAD(P)H dehydrogenase (quinone) activity
NX819_05315	COG1725	Transcriptional regulator
NX819_05320	COG1131	(ABC) transporter
NX819_05325	COG1131	(ABC) transporter
NX819_05330	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NX819_05335	COG1278	Cold shock
NX819_05340	COG1464	Belongs to the NlpA lipoprotein family
NX819_05345	COG3706	GGDEF domain
NX819_05350	COG1823	symporter activity
NX819_05370	COG5577	PFAM Coat F domain
NX819_05375	COG0737	Belongs to the 5'-nucleotidase family
NX819_05375	COG4085	toxin activity
NX819_05375	COG1525	nuclease
NX819_05380	COG3764	Sortase (surface protein transpeptidase)
NX819_05385	COG0564	pseudouridine synthase activity
NX819_05395	COG0517	IMP dehydrogenase activity
NX819_05400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NX819_05405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NX819_05405	COG3153	acetyltransferase
NX819_05410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NX819_05415	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NX819_05420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NX819_05425	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NX819_05430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NX819_05435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NX819_05440	COG4585	Histidine kinase
NX819_05440	COG2203	Gaf domain
NX819_05445	COG2197	response regulator
NX819_05450	COG0431	NADPH-dependent FMN reductase
NX819_05465	COG0791	NLP P60 protein
NX819_05465	COG1388	LysM domain
NX819_05470	COG1959	2 iron, 2 sulfur cluster binding
NX819_05475	COG0668	transmembrane transport
NX819_05480	COG2719	SpoVR family
NX819_05485	COG1785	Belongs to the alkaline phosphatase family
NX819_05490	COG0791	NLP P60 protein
NX819_05490	COG1388	LysM domain
NX819_05495	COG0583	DNA-binding transcription factor activity
NX819_05500	COG0372	Belongs to the citrate synthase family
NX819_05505	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_05510	COG0531	amino acid
NX819_05515	COG0733	neurotransmitter:sodium symporter activity
NX819_05520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX819_05540	COG1595	DNA-templated transcription, initiation
NX819_05545	COG0667	Aldo Keto reductase
NX819_05550	COG0204	Acyl-transferase
NX819_05555	COG1253	flavin adenine dinucleotide binding
NX819_05560	COG0789	Transcriptional regulator
NX819_05565	COG0436	Aminotransferase
NX819_05570	COG1253	flavin adenine dinucleotide binding
NX819_05575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NX819_05580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NX819_05585	COG0584	glycerophosphoryl diester phosphodiesterase
NX819_05595	COG0668	transmembrane transport
NX819_05600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NX819_05605	COG0726	polysaccharide deacetylase
NX819_05610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX819_05615	COG1757	Na H antiporter
NX819_05620	COG0589	response to stress
NX819_05630	COG1132	(ABC) transporter
NX819_05635	COG1132	(ABC) transporter
NX819_05640	COG0702	epimerase
NX819_05660	COG0189	ligase activity
NX819_05665	COG0189	ligase activity
NX819_05670	COG4399	Belongs to the UPF0754 family
NX819_05675	COG3679	Belongs to the UPF0342 family
NX819_05680	COG4335	DNA alkylation repair
NX819_05685	COG0561	phosphatase activity
NX819_05690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NX819_05695	COG0475	glutathione-regulated potassium exporter activity
NX819_05700	COG0490	domain, Protein
NX819_05710	COG1024	Enoyl-CoA hydratase
NX819_05720	COG4152	abc transporter atp-binding protein
NX819_05725	COG1668	transmembrane transport
NX819_05730	COG0420	3'-5' exonuclease activity
NX819_05735	COG4717	serine-type aminopeptidase activity
NX819_05740	COG3481	metal-dependent phosphohydrolase, HD sub domain
NX819_05750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NX819_05780	COG1846	Transcriptional regulator
NX819_05785	COG4980	gas vesicle protein
NX819_05800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NX819_05805	COG0537	adenosine 5'-monophosphoramidase activity
NX819_05810	COG1131	(ABC) transporter
NX819_05815	COG4473	ABC transporter
NX819_05825	COG1473	amidohydrolase
NX819_05830	COG3069	C4-dicarboxylate transmembrane transporter activity
NX819_05840	COG2329	Antibiotic biosynthesis monooxygenase
NX819_05845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NX819_05850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NX819_05855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NX819_05860	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NX819_05865	COG1309	transcriptional regulator
NX819_05870	COG1511	domain protein
NX819_05875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX819_05880	COG4377	Putative membrane peptidase family (DUF2324)
NX819_05890	COG1363	Peptidase, m42
NX819_05895	COG4405	Protein conserved in bacteria
NX819_05900	COG1301	dicarboxylic acid transport
NX819_05910	COG1234	tRNA 3'-trailer cleavage
NX819_05915	COG0095	Lipoate-protein ligase
NX819_05920	COG0702	epimerase
NX819_05925	COG0318	PFAM AMP-dependent synthetase and ligase
NX819_05935	COG0501	Belongs to the peptidase M48B family
NX819_05945	COG0456	acetyltransferase
NX819_05950	COG0604	alcohol dehydrogenase
NX819_05955	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NX819_05960	COG0406	alpha-ribazole phosphatase activity
NX819_05965	COG0183	Belongs to the thiolase family
NX819_05970	COG0318	PFAM AMP-dependent synthetase and ligase
NX819_05975	COG1268	BioY protein
NX819_05980	COG0840	transmembrane signaling receptor activity
NX819_05985	COG0723	plastoquinol--plastocyanin reductase activity
NX819_05985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX819_05990	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_06000	COG4903	ComK protein
NX819_06005	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_06015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX819_06030	COG0398	Pfam SNARE associated Golgi protein
NX819_06035	COG0681	Belongs to the peptidase S26 family
NX819_06040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX819_06045	COG1846	Transcriptional regulator
NX819_06050	COG0738	Major facilitator superfamily
NX819_06055	COG0673	inositol 2-dehydrogenase activity
NX819_06060	COG0561	phosphatase activity
NX819_06065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NX819_06070	COG1609	Transcriptional regulator
NX819_06075	COG3180	Ammonia monooxygenase
NX819_06080	COG0477	Major facilitator Superfamily
NX819_06080	COG2814	Major facilitator Superfamily
NX819_06085	COG4533	DNA binding
NX819_06095	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NX819_06100	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NX819_06105	COG1074	ATP-dependent DNA helicase activity
NX819_06110	COG0420	3'-5' exonuclease activity
NX819_06115	COG0419	ATPase involved in DNA repair
NX819_06120	COG1403	HNH endonuclease
NX819_06160	COG5337	Spore coat protein CotH
NX819_06165	COG0179	Fumarylacetoacetate (FAA) hydrolase
NX819_06175	COG1404	Belongs to the peptidase S8 family
NX819_06185	COG0367	asparagine synthase
NX819_06190	COG2318	DinB family
NX819_06195	COG1562	ergosterol biosynthetic process
NX819_06200	COG0534	Mate efflux family protein
NX819_06205	COG2207	Transcriptional regulator
NX819_06205	COG1917	Cupin 2, conserved barrel domain protein
NX819_06210	COG1609	Transcriptional regulator
NX819_06215	COG0673	inositol 2-dehydrogenase activity
NX819_06220	COG2318	DinB family
NX819_06225	COG1279	arginine transmembrane transporter activity
NX819_06230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX819_06235	COG1357	PFAM Pentapeptide repeats (8 copies)
NX819_06240	COG2267	carboxylic ester hydrolase activity
NX819_06245	COG0529	Catalyzes the synthesis of activated sulfate
NX819_06250	COG2046	Belongs to the sulfate adenylyltransferase family
NX819_06255	COG0175	sulfate reduction
NX819_06260	COG2045	Belongs to the ComB family
NX819_06265	COG1809	phosphosulfolactate synthase activity
NX819_06270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX819_06275	COG4948	Mandelate Racemase Muconate Lactonizing
NX819_06280	COG2814	Major facilitator Superfamily
NX819_06285	COG0454	-acetyltransferase
NX819_06290	COG2153	protein acetylation
NX819_06295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NX819_06295	COG0646	methionine synthase
NX819_06300	COG1666	GTP binding
NX819_06325	COG1695	Transcriptional regulator
NX819_06340	COG3227	Zinc metalloprotease (Elastase)
NX819_06345	COG1307	EDD domain protein, DegV family
NX819_06350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX819_06370	COG0561	phosphatase activity
NX819_06375	COG1073	alpha beta
NX819_06380	COG2151	metal-sulfur cluster biosynthetic enzyme
NX819_06390	COG0277	FAD linked oxidase domain protein
NX819_06395	COG2271	Major facilitator Superfamily
NX819_06400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NX819_06405	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NX819_06415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NX819_06420	COG0505	Belongs to the CarA family
NX819_06425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NX819_06430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NX819_06445	COG2267	carboxylic ester hydrolase activity
NX819_06455	COG1744	ABC transporter substrate-binding protein PnrA-like
NX819_06470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX819_06475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NX819_06480	COG5504	Zn-dependent protease
NX819_06485	COG0444	Belongs to the ABC transporter superfamily
NX819_06490	COG4608	Belongs to the ABC transporter superfamily
NX819_06500	COG0601	transmembrane transport
NX819_06505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NX819_06515	COG0180	Tryptophanyl-tRNA synthetase
NX819_06520	COG4166	transmembrane transport
NX819_06525	COG0601	transmembrane transport
NX819_06530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NX819_06535	COG0444	Belongs to the ABC transporter superfamily
NX819_06540	COG4608	Belongs to the ABC transporter superfamily
NX819_06545	COG2814	Major facilitator Superfamily
NX819_06550	COG0456	acetyltransferase
NX819_06555	COG1393	Belongs to the ArsC family
NX819_06560	COG0861	Integral membrane protein TerC family
NX819_06570	COG4862	establishment of competence for transformation
NX819_06580	COG4469	Competence protein
NX819_06585	COG1164	Oligoendopeptidase f
NX819_06595	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NX819_06600	COG2346	COG2346, Truncated hemoglobins
NX819_06605	COG0741	lytic transglycosylase activity
NX819_06610	COG4116	CYTH
NX819_06620	COG2357	RelA SpoT domain protein
NX819_06625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NX819_06630	COG0564	pseudouridine synthase activity
NX819_06635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NX819_06640	COG0569	domain protein
NX819_06640	COG0475	glutathione-regulated potassium exporter activity
NX819_06645	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NX819_06650	COG0352	thiamine-phosphate diphosphorylase activity
NX819_06655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX819_06660	COG2104	thiamine diphosphate biosynthetic process
NX819_06665	COG2022	thiamine diphosphate biosynthetic process
NX819_06670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NX819_06675	COG0351	phosphomethylpyrimidine kinase
NX819_06680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NX819_06735	COG0210	DNA helicase
NX819_06745	COG2153	protein acetylation
NX819_06750	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NX819_06755	COG2382	esterase
NX819_06760	COG0626	cystathionine gamma-synthase activity
NX819_06765	COG0626	cystathionine gamma-synthase activity
NX819_06770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX819_06775	COG5505	Protein of unknown function (DUF819)
NX819_06805	COG3677	Transposase
NX819_06820	COG5484	DNA packaging
NX819_06825	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NX819_06830	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_06840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX819_06840	COG3711	transcriptional antiterminator
NX819_06845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NX819_06845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NX819_06845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX819_06850	COG1482	cell wall glycoprotein biosynthetic process
NX819_06860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX819_06870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NX819_06885	COG0109	protoheme IX farnesyltransferase activity
NX819_06895	COG0726	polysaccharide deacetylase
NX819_06910	COG5504	Zn-dependent protease
NX819_06915	COG2205	protein histidine kinase activity
NX819_06925	COG3383	formate dehydrogenase (NAD+) activity
NX819_06930	COG2427	Protein of unknown function (DUF1641)
NX819_06940	COG1051	belongs to the nudix hydrolase family
NX819_06950	COG2124	cytochrome p450
NX819_06955	COG1819	glycosyl
NX819_06965	COG1587	Uroporphyrinogen-III synthase
NX819_06970	COG0390	transport system, permease component
NX819_06975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NX819_06980	COG0697	spore germination
NX819_06985	COG4297	protein containing double-stranded beta helix domain
NX819_06995	COG1252	NADH dehydrogenase
NX819_07000	COG1904	glucuronate isomerase
NX819_07005	COG2211	Major facilitator Superfamily
NX819_07010	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NX819_07015	COG1063	alcohol dehydrogenase
NX819_07020	COG1312	Catalyzes the dehydration of D-mannonate
NX819_07025	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_07030	COG2271	Major facilitator Superfamily
NX819_07035	COG1609	Transcriptional regulator
NX819_07040	COG0246	Mannitol dehydrogenase
NX819_07045	COG2721	sulfolactate sulfo-lyase activity
NX819_07050	COG0730	response to heat
NX819_07055	COG2318	DinB family
NX819_07060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NX819_07065	COG0457	Tetratricopeptide repeat
NX819_07075	COG2350	Protein conserved in bacteria
NX819_07080	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX819_07080	COG1388	LysM domain
NX819_07080	COG3409	Peptidoglycan-binding domain 1 protein
NX819_07090	COG4195	phage-related replication protein
NX819_07095	COG3546	catalase activity
NX819_07100	COG2856	Zn peptidase
NX819_07105	COG1396	sequence-specific DNA binding
NX819_07115	COG1522	sequence-specific DNA binding
NX819_07120	COG1484	DNA-dependent DNA replication
NX819_07140	COG1595	DNA-templated transcription, initiation
NX819_07145	COG3728	DNA packaging
NX819_07145	COG5484	DNA packaging
NX819_07150	COG1783	phage Terminase large subunit
NX819_07155	COG5518	Phage portal protein
NX819_07160	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NX819_07165	COG4653	Phage capsid family
NX819_07215	COG5412	phage tail tape measure protein
NX819_07215	COG3953	SLT domain
NX819_07220	COG1652	LysM domain
NX819_07225	COG4193	domain, Protein
NX819_07235	COG3628	GPW Gp25 family protein
NX819_07240	COG3299	homolog of phage Mu protein gp47
NX819_07245	COG3778	Protein conserved in bacteria
NX819_07285	COG3409	Peptidoglycan-binding domain 1 protein
NX819_07285	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX819_07305	COG0306	phosphate transporter
NX819_07310	COG1392	Phosphate transport regulator
NX819_07315	COG0531	amino acid
NX819_07320	COG0346	lactoylglutathione lyase activity
NX819_07330	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NX819_07335	COG0463	Glycosyl transferase, family 2
NX819_07345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX819_07350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NX819_07355	COG2362	D-Aminopeptidase
NX819_07360	COG0601	transmembrane transport
NX819_07365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NX819_07370	COG0444	Belongs to the ABC transporter superfamily
NX819_07375	COG4166	transmembrane transport
NX819_07380	COG1619	proteins homologs of microcin C7 resistance protein MccF
NX819_07385	COG4948	Mandelate Racemase Muconate Lactonizing
NX819_07390	COG0791	NLP P60 protein
NX819_07395	COG4608	Belongs to the ABC transporter superfamily
NX819_07400	COG2706	6-phosphogluconolactonase activity
NX819_07405	COG1834	amidinotransferase
NX819_07410	COG1607	acyl-coa hydrolase
NX819_07415	COG1017	nitric oxide dioxygenase activity
NX819_07415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NX819_07425	COG2323	membrane
NX819_07430	COG2318	DinB family
NX819_07435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX819_07440	COG2076	Multidrug Resistance protein
NX819_07445	COG2076	Multidrug Resistance protein
NX819_07450	COG0788	formyltetrahydrofolate deformylase activity
NX819_07455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NX819_07460	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NX819_07465	COG1764	response to oxidative stress
NX819_07470	COG1846	Transcriptional regulator
NX819_07475	COG1764	response to oxidative stress
NX819_07485	COG0590	tRNA wobble adenosine to inosine editing
NX819_07490	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NX819_07495	COG1404	Belongs to the peptidase S8 family
NX819_07500	COG1366	Belongs to the anti-sigma-factor antagonist family
NX819_07505	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NX819_07510	COG1122	ATPase activity
NX819_07515	COG4721	ABC-type cobalt transport system, permease component
NX819_07525	COG0745	RESPONSE REGULATOR receiver
NX819_07530	COG5002	protein histidine kinase activity
NX819_07530	COG3850	Histidine kinase
NX819_07535	COG3212	peptidase
NX819_07540	COG3212	peptidase
NX819_07555	COG2239	Acts as a magnesium transporter
NX819_07560	COG0789	Transcriptional regulator
NX819_07575	COG1846	Transcriptional regulator
NX819_07585	COG0726	polysaccharide deacetylase
NX819_07590	COG1408	metallophosphoesterase
NX819_07600	COG0463	Glycosyl transferase, family 2
NX819_07605	COG1793	dna ligase
NX819_07605	COG3285	dna ligase
NX819_07610	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NX819_07615	COG5001	Diguanylate cyclase
NX819_07615	COG3300	MHYT domain
NX819_07620	COG0586	Pfam SNARE associated Golgi protein
NX819_07625	COG0861	Integral membrane protein TerC family
NX819_07630	COG1191	sigma factor activity
NX819_07650	COG0501	Belongs to the peptidase M48B family
NX819_07655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NX819_07670	COG3594	Acyltransferase
NX819_07675	COG5002	protein histidine kinase activity
NX819_07680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NX819_07690	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NX819_07695	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NX819_07700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NX819_07705	COG0436	Aminotransferase
NX819_07710	COG1850	ribulose-bisphosphate carboxylase activity
NX819_07715	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NX819_07720	COG0235	Class ii aldolase
NX819_07725	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NX819_07730	COG3339	Conserved Protein
NX819_07745	COG3852	Histidine kinase
NX819_07750	COG1846	Transcriptional regulator
NX819_07755	COG1360	Flagellar Motor Protein
NX819_07760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NX819_07765	COG0542	response to heat
NX819_07770	COG3949	Membrane
NX819_07775	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NX819_07780	COG0720	synthase
NX819_07785	COG0602	queuosine metabolic process
NX819_07790	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NX819_07795	COG1733	regulation of RNA biosynthetic process
NX819_07800	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_07805	COG4641	Protein conserved in bacteria
NX819_07805	COG1388	LysM domain
NX819_07810	COG1388	LysM domain
NX819_07815	COG3858	chitin binding
NX819_07825	COG4873	Protein conserved in bacteria
NX819_07835	COG3773	Cell wall hydrolase
NX819_07840	COG2244	polysaccharide biosynthetic process
NX819_07845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX819_07850	COG2217	Heavy metal translocating P-type atpase
NX819_07860	COG0006	proline dipeptidase activity
NX819_07865	COG1609	Transcriptional regulator
NX819_07870	COG3711	transcriptional antiterminator
NX819_07875	COG2190	(PTS) system
NX819_07875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_07875	COG1263	PTS System
NX819_07880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX819_07885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NX819_07895	COG1533	DNA photolyase activity
NX819_07900	COG0456	acetyltransferase
NX819_07905	COG0840	transmembrane signaling receptor activity
NX819_07910	COG2084	Dehydrogenase
NX819_07915	COG2340	Cysteine-rich secretory protein family
NX819_07920	COG0768	penicillin binding
NX819_07925	COG4191	Histidine kinase
NX819_07930	COG0436	Aminotransferase
NX819_07940	COG0835	chemotaxis
NX819_07940	COG0784	Response regulator, receiver
NX819_07950	COG2814	Major facilitator Superfamily
NX819_07955	COG1376	ErfK ybiS ycfS ynhG family protein
NX819_07960	COG1408	metallophosphoesterase
NX819_07965	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_07975	COG3409	Peptidoglycan-binding domain 1 protein
NX819_07985	COG2200	EAL domain
NX819_07990	COG4703	Protein of unknown function (DUF1797)
NX819_07995	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NX819_08005	COG0517	IMP dehydrogenase activity
NX819_08010	COG0583	DNA-binding transcription factor activity
NX819_08015	COG0716	FMN binding
NX819_08025	COG0716	FMN binding
NX819_08030	COG2171	N-acyltransferase activity
NX819_08035	COG1473	amidohydrolase
NX819_08045	COG0668	transmembrane transport
NX819_08050	COG0450	alkyl hydroperoxide reductase
NX819_08055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX819_08070	COG0746	molybdenum cofactor guanylyltransferase activity
NX819_08075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NX819_08080	COG0303	'Molybdopterin
NX819_08085	COG1763	Mo-molybdopterin cofactor biosynthetic process
NX819_08090	COG0314	molybdopterin synthase activity
NX819_08095	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NX819_08100	COG1132	(ABC) transporter
NX819_08105	COG1132	(ABC) transporter
NX819_08115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX819_08120	COG1136	(ABC) transporter
NX819_08125	COG0577	efflux transmembrane transporter activity
NX819_08130	COG1349	DNA-binding transcription factor activity
NX819_08135	COG1105	Belongs to the carbohydrate kinase PfkB family
NX819_08140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX819_08140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NX819_08140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NX819_08145	COG0681	Belongs to the peptidase S26 family
NX819_08155	COG0488	(ABC) transporter
NX819_08160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NX819_08165	COG2309	aminopeptidase activity
NX819_08175	COG1077	Cell shape determining protein MreB Mrl
NX819_08180	COG2002	toxin-antitoxin pair type II binding
NX819_08185	COG3852	Histidine kinase
NX819_08190	COG2105	PFAM AIG2 family protein
NX819_08190	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NX819_08195	COG0569	domain protein
NX819_08200	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NX819_08205	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NX819_08210	COG5503	Protein of unknown function (DUF1447)
NX819_08215	COG0561	phosphatase activity
NX819_08220	COG0242	peptide deformylase activity
NX819_08230	COG0497	DNA recombination
NX819_08235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NX819_08240	COG0022	dehydrogenase e1 component
NX819_08245	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX819_08250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NX819_08255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX819_08265	COG1982	Orn Lys Arg decarboxylase major
NX819_08270	COG4476	Belongs to the UPF0223 family
NX819_08275	COG4493	Belongs to the UPF0637 family
NX819_08285	COG0483	inositol monophosphate 1-phosphatase activity
NX819_08295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NX819_08315	COG1595	DNA-templated transcription, initiation
NX819_08335	COG1217	gtp-binding protein TYPA
NX819_08345	COG4896	Protein conserved in bacteria
NX819_08355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NX819_08360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NX819_08365	COG2066	Belongs to the glutaminase family
NX819_08370	COG4838	Belongs to the UPF0358 family
NX819_08375	COG0772	Belongs to the SEDS family
NX819_08380	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NX819_08385	COG1612	heme a metabolic process
NX819_08390	COG0109	protoheme IX farnesyltransferase activity
NX819_08395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NX819_08395	COG2010	Cytochrome c
NX819_08400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NX819_08405	COG1845	cytochrome c oxidase, subunit III
NX819_08410	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NX819_08415	COG3336	cytochrome c oxidase
NX819_08425	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NX819_08430	COG2340	Cysteine-rich secretory protein family
NX819_08445	COG3679	Belongs to the UPF0342 family
NX819_08450	COG4471	UPF0298 protein
NX819_08455	COG0742	ribosomal rna small subunit methyltransferase
NX819_08460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NX819_08465	COG3314	Sporulation integral membrane protein YlbJ
NX819_08470	COG1752	Esterase of the alpha-beta hydrolase superfamily
NX819_08475	COG3480	Lon protease (S16) C-terminal proteolytic domain
NX819_08480	COG1323	Belongs to the UPF0348 family
NX819_08490	COG1399	metal-binding, possibly nucleic acid-binding protein
NX819_08505	COG0454	-acetyltransferase
NX819_08510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NX819_08515	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NX819_08520	COG2001	Belongs to the MraZ family
NX819_08525	COG0275	rRNA processing
NX819_08530	COG4839	cell division protein FtsL
NX819_08535	COG0768	penicillin binding
NX819_08540	COG0768	penicillin binding
NX819_08545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NX819_08550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NX819_08555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NX819_08560	COG0772	Belongs to the SEDS family
NX819_08565	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NX819_08570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NX819_08575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NX819_08580	COG3879	Bacterial protein of unknown function (DUF881)
NX819_08585	COG3879	Bacterial protein of unknown function (DUF881)
NX819_08590	COG3856	small basic protein
NX819_08595	COG0849	cell division
NX819_08600	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NX819_08605	COG4412	M6 family metalloprotease domain protein
NX819_08605	COG1404	Belongs to the peptidase S8 family
NX819_08615	COG1191	sigma factor activity
NX819_08620	COG1191	sigma factor activity
NX819_08625	COG1119	ATPase activity
NX819_08630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX819_08635	COG1873	PFAM PRC-barrel domain
NX819_08640	COG1496	oxidoreductase activity
NX819_08645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NX819_08650	COG1799	cell septum assembly
NX819_08655	COG0762	integral membrane protein
NX819_08660	COG2302	S4 RNA-binding domain
NX819_08665	COG3599	regulation of cell shape
NX819_08670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NX819_08675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX819_08680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NX819_08685	COG0564	pseudouridine synthase activity
NX819_08690	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NX819_08695	COG2233	PERMEase
NX819_08700	COG0540	Belongs to the ATCase OTCase family
NX819_08705	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NX819_08710	COG0505	Belongs to the CarA family
NX819_08715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NX819_08720	COG0543	2 iron, 2 sulfur cluster binding
NX819_08725	COG0167	dihydroorotate dehydrogenase activity
NX819_08730	COG0284	orotidine-5'-phosphate decarboxylase activity
NX819_08735	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NX819_08740	COG0175	sulfate reduction
NX819_08745	COG0306	phosphate transporter
NX819_08750	COG2046	Belongs to the sulfate adenylyltransferase family
NX819_08755	COG0529	Catalyzes the synthesis of activated sulfate
NX819_08760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NX819_08765	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NX819_08770	COG1648	precorrin-2 dehydrogenase activity
NX819_08775	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NX819_08780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NX819_08785	COG1561	YicC-like family, N-terminal region
NX819_08795	COG0194	GDP metabolic process
NX819_08800	COG1758	RNA polymerase activity
NX819_08805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NX819_08810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NX819_08815	COG0242	peptide deformylase activity
NX819_08820	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NX819_08825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NX819_08825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NX819_08830	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NX819_08835	COG0631	protein serine/threonine phosphatase activity
NX819_08840	COG0515	serine threonine protein kinase
NX819_08840	COG2815	serine threonine protein kinase
NX819_08845	COG1162	GTPase activity
NX819_08850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NX819_08855	COG1564	THIamine pyrophosphokinase
NX819_08865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NX819_08870	COG1302	Protein conserved in bacteria
NX819_08875	COG1461	Dihydroxyacetone kinase
NX819_08880	COG1760	l-serine dehydratase
NX819_08885	COG1760	l-serine dehydratase
NX819_08890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NX819_08895	COG1349	DNA-binding transcription factor activity
NX819_08895	COG2050	protein possibly involved in aromatic compounds catabolism
NX819_08900	COG0416	fatty acid biosynthetic process
NX819_08905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NX819_08910	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_08920	COG0571	ribonuclease III activity
NX819_08925	COG1196	nuclear chromosome segregation
NX819_08930	COG0552	protein localization to endoplasmic reticulum
NX819_08940	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NX819_08945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NX819_08950	COG0228	four-way junction DNA binding
NX819_08955	COG1837	Belongs to the UPF0109 family
NX819_08965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NX819_08970	COG0336	Belongs to the RNA methyltransferase TrmD family
NX819_08975	COG0335	large ribosomal subunit rRNA binding
NX819_08980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NX819_08985	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NX819_08995	COG2257	FlhB HrpN YscU SpaS Family
NX819_09000	COG0045	succinate-CoA ligase (ADP-forming) activity
NX819_09005	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NX819_09010	COG0758	DNA mediated transformation
NX819_09015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NX819_09020	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NX819_09025	COG4974	Belongs to the 'phage' integrase family
NX819_09030	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NX819_09035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NX819_09040	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NX819_09045	COG1815	bacterial-type flagellum-dependent cell motility
NX819_09050	COG1558	bacterial-type flagellum-dependent cell motility
NX819_09055	COG1677	Flagellar hook-basal body complex protein FliE
NX819_09060	COG1766	The M ring may be actively involved in energy transduction
NX819_09065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NX819_09070	COG1317	bacterial-type flagellum organization
NX819_09075	COG1157	protein secretion by the type III secretion system
NX819_09080	COG2882	bacterial-type flagellum organization
NX819_09085	COG3334	PFAM MgtE intracellular
NX819_09090	COG3144	bacterial-type flagellum assembly
NX819_09095	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NX819_09100	COG4786	Flagellar basal body rod
NX819_09105	COG1582	Flagellar protein (FlbD)
NX819_09110	COG1580	Controls the rotational direction of flagella during chemotaxis
NX819_09115	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NX819_09120	COG1776	CheC inhibitor of MCP methylation
NX819_09120	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NX819_09125	COG2201	protein-glutamate methylesterase activity
NX819_09130	COG3190	flagellar
NX819_09135	COG1338	Plays a role in the flagellum-specific transport system
NX819_09140	COG1987	bacterial-type flagellum assembly
NX819_09145	COG1684	flagellar biosynthetic protein fliR
NX819_09150	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NX819_09155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NX819_09160	COG1419	protein localization to endoplasmic reticulum
NX819_09165	COG0455	bacterial-type flagellum organization
NX819_09170	COG2201	protein-glutamate methylesterase activity
NX819_09175	COG2198	Histidine kinase
NX819_09175	COG0643	Histidine kinase
NX819_09180	COG0835	chemotaxis
NX819_09185	COG1776	CheC inhibitor of MCP methylation
NX819_09190	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NX819_09195	COG1191	sigma factor activity
NX819_09205	COG0052	Belongs to the universal ribosomal protein uS2 family
NX819_09210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NX819_09215	COG0528	UMP kinase activity
NX819_09220	COG0233	cytoplasmic translational termination
NX819_09225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NX819_09230	COG4589	Belongs to the CDS family
NX819_09235	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NX819_09240	COG0750	zinc metalloprotease
NX819_09245	COG0442	prolyl-tRNA aminoacylation
NX819_09250	COG2176	DNA-directed DNA polymerase activity
NX819_09255	COG0779	Required for maturation of 30S ribosomal subunits
NX819_09260	COG0195	Participates in both transcription termination and antitermination
NX819_09265	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NX819_09270	COG1358	cellular component organization or biogenesis
NX819_09275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NX819_09280	COG1550	Protein conserved in bacteria
NX819_09285	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NX819_09290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NX819_09295	COG0196	riboflavin kinase activity
NX819_09300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NX819_09305	COG1185	polyribonucleotide nucleotidyltransferase activity
NX819_09310	COG0726	polysaccharide deacetylase
NX819_09315	COG0612	Peptidase, M16
NX819_09320	COG1873	PFAM PRC-barrel domain
NX819_09325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NX819_09330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NX819_09335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NX819_09340	COG0527	aspartate kinase activity
NX819_09345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NX819_09350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NX819_09355	COG0740	serine-type endopeptidase activity
NX819_09365	COG4980	gas vesicle protein
NX819_09365	COG1674	ftsk spoiiie
NX819_09370	COG2188	Transcriptional regulator
NX819_09375	COG2814	Major facilitator Superfamily
NX819_09380	COG0612	Peptidase, M16
NX819_09385	COG0612	Peptidase, M16
NX819_09390	COG0300	oxidoreductase activity
NX819_09405	COG1426	Protein conserved in bacteria
NX819_09410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NX819_09415	COG1058	Belongs to the CinA family
NX819_09415	COG1546	Belongs to the CinA family
NX819_09420	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NX819_09425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NX819_09430	COG1418	mRNA catabolic process
NX819_09435	COG1692	metallophosphoesterase
NX819_09440	COG2359	stage V sporulation protein S
NX819_09445	COG1063	alcohol dehydrogenase
NX819_09450	COG0156	8-amino-7-oxononanoate synthase activity
NX819_09455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NX819_09460	COG4550	Control of competence regulator ComK, YlbF/YmcA
NX819_09470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NX819_09475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NX819_09490	COG3226	Transcriptional regulator
NX819_09495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX819_09505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NX819_09510	COG3321	synthase
NX819_09515	COG2070	2-Nitropropane dioxygenase
NX819_09515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NX819_09520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NX819_09525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NX819_09530	COG3425	synthase
NX819_09535	COG1024	Enoyl-CoA hydratase
NX819_09540	COG1024	Enoyl-CoA hydratase
NX819_09545	COG0300	oxidoreductase activity
NX819_09545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_09545	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_09545	COG3321	synthase
NX819_09545	COG0318	PFAM AMP-dependent synthetase and ligase
NX819_09550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NX819_09550	COG0300	oxidoreductase activity
NX819_09550	COG3321	synthase
NX819_09550	COG4221	oxidoreductase activity
NX819_09555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NX819_09555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX819_09555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_09555	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_09555	COG3321	synthase
NX819_09560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_09560	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_09560	COG4221	oxidoreductase activity
NX819_09560	COG3321	synthase
NX819_09565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NX819_09565	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NX819_09565	COG3321	synthase
NX819_09565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NX819_09570	COG2124	cytochrome p450
NX819_09580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX819_09585	COG1404	Belongs to the peptidase S8 family
NX819_09595	COG4195	phage-related replication protein
NX819_09600	COG1764	response to oxidative stress
NX819_09605	COG2076	Multidrug Resistance protein
NX819_09610	COG2076	Multidrug Resistance protein
NX819_09625	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NX819_09630	COG1923	regulation of RNA biosynthetic process
NX819_09645	COG1780	Probably involved in ribonucleotide reductase function
NX819_09650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NX819_09655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NX819_09660	COG4112	unkown
NX819_09665	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX819_09670	COG0464	growth
NX819_09675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NX819_09680	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NX819_09685	COG0789	Transcriptional regulator
NX819_09690	COG0174	glutamine synthetase
NX819_09710	COG4282	regulation of fungal-type cell wall biogenesis
NX819_09720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX819_09750	COG0135	phosphoribosylanthranilate isomerase activity
NX819_09755	COG2211	Major facilitator Superfamily
NX819_09760	COG3507	Belongs to the glycosyl hydrolase 43 family
NX819_09765	COG1940	carbohydrate kinase activity
NX819_09770	COG2115	Belongs to the xylose isomerase family
NX819_09775	COG1070	Carbohydrate kinase
NX819_09785	COG1525	nuclease
NX819_09790	COG2814	Major facilitator Superfamily
NX819_09795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NX819_09805	COG0756	dUTP diphosphatase activity
NX819_09820	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NX819_09845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NX819_09860	COG3832	glyoxalase III activity
NX819_09870	COG0697	spore germination
NX819_09875	COG0531	amino acid
NX819_09905	COG4195	phage-related replication protein
NX819_09915	COG0346	lactoylglutathione lyase activity
NX819_09925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NX819_09930	COG1388	LysM domain
NX819_09935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX819_09940	COG4224	UPF0291 protein
NX819_09945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NX819_09955	COG3763	UPF0154 protein
NX819_09965	COG0785	Cytochrome C biogenesis protein
NX819_09970	COG2201	protein-glutamate methylesterase activity
NX819_09975	COG4846	Membrane protein involved in cytochrome C biogenesis
NX819_09985	COG0071	Belongs to the small heat shock protein (HSP20) family
NX819_10000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NX819_10005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX819_10025	COG0824	Thioesterase
NX819_10035	COG4841	protein insertion into membrane
NX819_10040	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NX819_10045	COG1832	CoA-binding protein
NX819_10050	COG0187	DNA topoisomerase II activity
NX819_10055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NX819_10070	COG1115	amino acid carrier protein
NX819_10075	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX819_10085	COG5520	Belongs to the glycosyl hydrolase 30 family
NX819_10090	COG3507	Belongs to the glycosyl hydrolase 43 family
NX819_10095	COG2246	polysaccharide biosynthetic process
NX819_10100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NX819_10105	COG0586	Pfam SNARE associated Golgi protein
NX819_10110	COG2404	hydrolase activity, acting on ester bonds
NX819_10115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NX819_10120	COG1024	Enoyl-CoA hydratase
NX819_10125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NX819_10130	COG0511	ligase activity, forming carbon-carbon bonds
NX819_10135	COG0439	Biotin carboxylase
NX819_10140	COG0318	PFAM AMP-dependent synthetase and ligase
NX819_10145	COG1960	acyl-CoA dehydrogenase activity
NX819_10160	COG1649	PFAM Uncharacterised BCR, COG1649
NX819_10170	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NX819_10170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_10175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_10180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_10185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_10190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_10195	COG2027	D-alanyl-D-alanine carboxypeptidase
NX819_10200	COG2017	converts alpha-aldose to the beta-anomer
NX819_10205	COG0534	Mate efflux family protein
NX819_10220	COG0582	viral genome integration into host DNA
NX819_10225	COG0166	Belongs to the GPI family
NX819_10230	COG0405	Gamma-glutamyltransferase
NX819_10235	COG0583	DNA-binding transcription factor activity
NX819_10240	COG0604	alcohol dehydrogenase
NX819_10245	COG0493	'glutamate synthase
NX819_10250	COG0070	glutamate synthase
NX819_10250	COG0069	glutamate synthase activity
NX819_10250	COG0067	glutamate synthase
NX819_10255	COG0583	DNA-binding transcription factor activity
NX819_10260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NX819_10265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NX819_10275	COG0300	oxidoreductase activity
NX819_10280	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NX819_10290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX819_10295	COG2814	Major facilitator Superfamily
NX819_10300	COG1070	Carbohydrate kinase
NX819_10305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NX819_10310	COG0243	molybdopterin cofactor binding
NX819_10340	COG0840	transmembrane signaling receptor activity
NX819_10340	COG5278	phosphoserine phosphatase activity
NX819_10345	COG2368	4-hydroxyphenylacetate
NX819_10350	COG4305	rare lipoprotein A
NX819_10355	COG3619	membrane
NX819_10360	COG3866	Pectate lyase
NX819_10365	COG2135	peptidase activity
NX819_10375	COG2140	Oxalate decarboxylase
NX819_10390	COG0456	acetyltransferase
NX819_10410	COG2720	vancomycin resistance protein
NX819_10420	COG3655	Transcriptional regulator
NX819_10425	COG3739	integral membrane protein
NX819_10430	COG0583	DNA-binding transcription factor activity
NX819_10435	COG0697	spore germination
NX819_10445	COG0693	protein deglycase activity
NX819_10450	COG2367	Beta-lactamase
NX819_10465	COG0574	Belongs to the PEP-utilizing enzyme family
NX819_10465	COG3848	Pyruvate phosphate dikinase
NX819_10470	COG0726	polysaccharide deacetylase
NX819_10475	COG2314	TM2 domain
NX819_10480	COG1396	sequence-specific DNA binding
NX819_10500	COG2135	peptidase activity
NX819_10540	COG0457	Tetratricopeptide repeat
NX819_10565	COG5290	Psort location Cytoplasmic, score
NX819_10590	COG5444	nuclease activity
NX819_10595	COG4282	regulation of fungal-type cell wall biogenesis
NX819_10600	COG1231	oxidoreductase activity
NX819_10605	COG5434	Belongs to the glycosyl hydrolase 28 family
NX819_10610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX819_10615	COG2207	Transcriptional regulator
NX819_10615	COG0662	Cupin 2, conserved barrel domain protein
NX819_10620	COG0456	acetyltransferase
NX819_10625	COG1309	transcriptional regulator
NX819_10630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX819_10635	COG3708	Transcriptional regulator
NX819_10640	COG2378	regulation of single-species biofilm formation
NX819_10650	COG0640	Transcriptional regulator
NX819_10655	COG0741	lytic transglycosylase activity
NX819_10660	COG2322	membrane
NX819_10675	COG1619	proteins homologs of microcin C7 resistance protein MccF
NX819_10680	COG3239	Fatty acid desaturase
NX819_10685	COG4585	Histidine kinase
NX819_10690	COG2197	response regulator
NX819_10695	COG3584	3D domain protein
NX819_10695	COG1388	LysM domain
NX819_10700	COG0514	ATP-dependent DNA helicase (RecQ)
NX819_10710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NX819_10715	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX819_10730	COG0071	Belongs to the small heat shock protein (HSP20) family
NX819_10755	COG1012	belongs to the aldehyde dehydrogenase family
NX819_10760	COG1657	PFAM Prenyltransferase squalene oxidase
NX819_10765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NX819_10770	COG0733	neurotransmitter:sodium symporter activity
NX819_10775	COG0385	Bile acid
NX819_10780	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX819_10785	COG0567	Dehydrogenase, E1 component
NX819_10790	COG4548	von Willebrand factor, type A
NX819_10795	COG0714	Associated with various cellular activities
NX819_10800	COG2032	superoxide dismutase activity
NX819_10805	COG1388	LysM domain
NX819_10805	COG0791	NLP P60 protein
NX819_10810	COG1819	glycosyl
NX819_10815	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NX819_10820	COG0534	Mate efflux family protein
NX819_10825	COG1366	Belongs to the anti-sigma-factor antagonist family
NX819_10830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NX819_10835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NX819_10845	COG2962	Rard protein
NX819_10860	COG2610	gluconate transmembrane transporter activity
NX819_10865	COG1942	4-Oxalocrotonate Tautomerase
NX819_10870	COG1733	regulation of RNA biosynthetic process
NX819_10875	COG0778	Nitroreductase
NX819_10880	COG0400	carboxylic ester hydrolase activity
NX819_10885	COG0346	lactoylglutathione lyase activity
NX819_10895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX819_10900	COG0793	Belongs to the peptidase S41A family
NX819_10900	COG3409	Peptidoglycan-binding domain 1 protein
NX819_10905	COG2226	methyltransferase
NX819_10915	COG1876	peptidase activity
NX819_10920	COG0813	purine-nucleoside phosphorylase activity
NX819_10935	COG0671	phosphoesterase, PA-phosphatase related
NX819_10955	COG4479	Belongs to the UPF0346 family
NX819_10965	COG1509	lysine 2,3-aminomutase activity
NX819_10970	COG0456	acetyltransferase
NX819_10975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX819_10980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NX819_10985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NX819_10990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NX819_11005	COG0456	acetyltransferase
NX819_11010	COG0463	Glycosyl transferase, family 2
NX819_11025	COG4641	Protein conserved in bacteria
NX819_11030	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
NX819_11035	COG1086	Polysaccharide biosynthesis protein
NX819_11040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NX819_11045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NX819_11050	COG1846	Transcriptional regulator
NX819_11055	COG0534	Mate efflux family protein
NX819_11065	COG4698	Protein conserved in bacteria
NX819_11070	COG2755	lipolytic protein G-D-S-L family
NX819_11075	COG1999	signal sequence binding
NX819_11085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NX819_11090	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NX819_11095	COG1272	protein, Hemolysin III
NX819_11100	COG0204	Acyl-transferase
NX819_11105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NX819_11110	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NX819_11115	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NX819_11125	COG2136	Putative SAM-dependent methyltransferase
NX819_11125	COG2521	methyltransferase
NX819_11135	COG0129	dihydroxy-acid dehydratase activity
NX819_11140	COG1413	lyase activity
NX819_11145	COG1418	mRNA catabolic process
NX819_11150	COG0386	Belongs to the glutathione peroxidase family
NX819_11155	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NX819_11160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NX819_11170	COG1278	Cold shock
NX819_11190	COG0328	RNA-DNA hybrid ribonuclease activity
NX819_11195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NX819_11200	COG0328	RNA-DNA hybrid ribonuclease activity
NX819_11210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NX819_11225	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NX819_11235	COG1755	Isoprenylcysteine carboxyl methyltransferase
NX819_11240	COG3424	synthase
NX819_11245	COG2233	PERMEase
NX819_11250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NX819_11255	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NX819_11265	COG0800	Aldolase
NX819_11270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX819_11275	COG1609	Transcriptional regulator
NX819_11280	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NX819_11285	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_11290	COG1199	ATP-dependent helicase activity
NX819_11305	COG0116	Belongs to the methyltransferase superfamily
NX819_11320	COG4474	Belongs to the UPF0398 family
NX819_11335	COG3359	exonuclease
NX819_11340	COG1205	dead DEAH box helicase
NX819_11340	COG1111	helicase
NX819_11345	COG2190	(PTS) system
NX819_11350	COG0071	Belongs to the small heat shock protein (HSP20) family
NX819_11385	COG3331	DNA recombination
NX819_11390	COG4499	WXG100 protein secretion system (Wss), protein YukC
NX819_11390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NX819_11400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NX819_11405	COG3935	DnaD domain protein
NX819_11410	COG0017	Asparaginyl-tRNA synthetase
NX819_11415	COG0436	Aminotransferase
NX819_11420	COG5353	protein conserved in bacteria
NX819_11430	COG1199	ATP-dependent helicase activity
NX819_11430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NX819_11435	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NX819_11440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NX819_11445	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NX819_11450	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NX819_11450	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NX819_11455	COG0617	tRNA 3'-terminal CCA addition
NX819_11460	COG0438	transferase activity, transferring glycosyl groups
NX819_11465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NX819_11470	COG1803	Methylglyoxal synthase
NX819_11475	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NX819_11480	COG1694	Mazg nucleotide pyrophosphohydrolase
NX819_11485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX819_11495	COG4347	Protein of unknown function (DUF1405)
NX819_11500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NX819_11500	COG2010	Cytochrome c
NX819_11505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NX819_11510	COG0723	plastoquinol--plastocyanin reductase activity
NX819_11520	COG5582	Belongs to the UPF0302 family
NX819_11525	COG0457	Tetratricopeptide repeat
NX819_11530	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NX819_11535	COG0287	Prephenate dehydrogenase
NX819_11540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NX819_11545	COG0159	tryptophan synthase activity
NX819_11550	COG0133	tryptophan synthase activity
NX819_11555	COG0135	phosphoribosylanthranilate isomerase activity
NX819_11565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NX819_11570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NX819_11575	COG4401	Chorismate mutase type I
NX819_11580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NX819_11585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NX819_11590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NX819_11595	COG0105	UTP biosynthetic process
NX819_11600	COG0142	geranyltranstransferase activity
NX819_11605	COG2226	methyltransferase
NX819_11610	COG0142	geranyltranstransferase activity
NX819_11620	COG0302	gtp cyclohydrolase
NX819_11625	COG0776	regulation of translation
NX819_11630	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NX819_11645	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NX819_11650	COG1160	GTP binding
NX819_11675	COG1304	FMN binding
NX819_11680	COG0539	negative regulation of cytoplasmic translation
NX819_11685	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NX819_11695	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NX819_11700	COG2959	enzyme of heme biosynthesis
NX819_11705	COG3773	Cell wall hydrolase
NX819_11705	COG3409	Peptidoglycan-binding domain 1 protein
NX819_11710	COG2339	peptidase activity
NX819_11715	COG0492	ferredoxin-NADP+ reductase activity
NX819_11720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NX819_11725	COG4862	establishment of competence for transformation
NX819_11730	COG1408	metallophosphoesterase
NX819_11740	COG1388	LysM domain
NX819_11745	COG1266	CAAX protease self-immunity
NX819_11750	COG0514	ATP-dependent DNA helicase (RecQ)
NX819_11755	COG4955	Helix-turn-helix domain
NX819_11760	COG1141	Ferredoxin
NX819_11765	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NX819_11770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NX819_11775	COG0710	3-dehydroquinate dehydratase activity
NX819_11785	COG1595	DNA-templated transcription, initiation
NX819_11790	COG5002	protein histidine kinase activity
NX819_11795	COG0745	RESPONSE REGULATOR receiver
NX819_11800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NX819_11805	COG1333	cytochrome c biogenesis protein
NX819_11810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX819_11815	COG1187	pseudouridine synthase activity
NX819_11820	COG0700	Nucleoside recognition
NX819_11825	COG2715	membrane protein required for spore maturation
NX819_11830	COG1686	Belongs to the peptidase S11 family
NX819_11840	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NX819_11845	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NX819_11850	COG1547	Domain of unknown function (DUF309)
NX819_11855	COG0456	acetyltransferase
NX819_11860	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NX819_11865	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NX819_11865	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NX819_11870	COG0307	riboflavin synthase, alpha
NX819_11875	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NX819_11875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NX819_11885	COG0681	Belongs to the peptidase S26 family
NX819_11895	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NX819_11915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NX819_11920	COG4086	secreted protein
NX819_11925	COG0019	diaminopimelate decarboxylase activity
NX819_11930	COG0697	spore germination
NX819_11945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX819_11965	COG1191	sigma factor activity
NX819_11970	COG2172	sigma factor antagonist activity
NX819_11975	COG1366	Belongs to the anti-sigma-factor antagonist family
NX819_11980	COG1686	Belongs to the peptidase S11 family
NX819_11985	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NX819_11990	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NX819_11995	COG4974	Belongs to the 'phage' integrase family
NX819_12005	COG0735	belongs to the Fur family
NX819_12010	COG1300	Membrane
NX819_12020	COG0281	malic enzyme
NX819_12025	COG1757	Na H antiporter
NX819_12030	COG1027	Aspartate ammonia-lyase
NX819_12035	COG0252	asparaginase activity
NX819_12040	COG1396	sequence-specific DNA binding
NX819_12045	COG1379	DNA repair
NX819_12050	COG0494	nUDIX hydrolase
NX819_12060	COG0667	Aldo Keto reductase
NX819_12070	COG1073	alpha beta
NX819_12080	COG4918	Iron-sulphur cluster biosynthesis
NX819_12085	COG0456	acetyltransferase
NX819_12085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NX819_12090	COG2329	Antibiotic biosynthesis monooxygenase
NX819_12095	COG0456	acetyltransferase
NX819_12105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NX819_12120	COG2211	Major facilitator Superfamily
NX819_12130	COG0346	lactoylglutathione lyase activity
NX819_12135	COG1072	(Pantothenic acid kinase))
NX819_12140	COG3048	D-serine ammonia-lyase activity
NX819_12145	COG0300	oxidoreductase activity
NX819_12150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX819_12155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NX819_12160	COG4187	Peptidase family M20/M25/M40
NX819_12165	COG1902	pentaerythritol trinitrate reductase activity
NX819_12170	COG0596	Alpha beta hydrolase
NX819_12180	COG1234	tRNA 3'-trailer cleavage
NX819_12185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NX819_12190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NX819_12195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NX819_12205	COG0706	membrane insertase activity
NX819_12230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NX819_12235	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_12240	COG2986	histidine ammonia-lyase
NX819_12250	COG0109	protoheme IX farnesyltransferase activity
NX819_12255	COG3361	conserved protein (COG2071)
NX819_12260	COG2195	Cleaves the N-terminal amino acid of tripeptides
NX819_12265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NX819_12270	COG0346	lactoylglutathione lyase activity
NX819_12280	COG1376	ErfK ybiS ycfS ynhG family protein
NX819_12285	COG4129	membrane
NX819_12290	COG1126	abc transporter atp-binding protein
NX819_12295	COG0765	amino acid transport
NX819_12300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX819_12310	COG1597	lipid kinase activity
NX819_12315	COG2814	Major facilitator Superfamily
NX819_12320	COG0789	Transcriptional regulator
NX819_12320	COG4978	Transcriptional regulator
NX819_12325	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX819_12330	COG0022	dehydrogenase e1 component
NX819_12335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NX819_12340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NX819_12345	COG3426	butyrate kinase activity
NX819_12350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NX819_12355	COG0280	phosphate acetyltransferase
NX819_12360	COG3290	protein histidine kinase activity
NX819_12360	COG3829	transcription factor binding
NX819_12370	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NX819_12375	COG2079	MmgE PrpD family protein
NX819_12380	COG0372	Belongs to the citrate synthase family
NX819_12385	COG1960	acyl-CoA dehydrogenase activity
NX819_12390	COG1250	3-hydroxyacyl-CoA dehydrogenase
NX819_12395	COG0183	Belongs to the thiolase family
NX819_12400	COG0584	glycerophosphoryl diester phosphodiesterase
NX819_12405	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX819_12420	COG1902	pentaerythritol trinitrate reductase activity
NX819_12425	COG0745	RESPONSE REGULATOR receiver
NX819_12430	COG0750	zinc metalloprotease
NX819_12435	COG0497	DNA recombination
NX819_12440	COG1438	arginine binding
NX819_12445	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NX819_12450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NX819_12455	COG0142	geranyltranstransferase activity
NX819_12460	COG1722	exodeoxyribonuclease VII activity
NX819_12465	COG1570	exodeoxyribonuclease VII activity
NX819_12470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NX819_12475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NX819_12480	COG1302	Protein conserved in bacteria
NX819_12485	COG0439	Biotin carboxylase
NX819_12490	COG0511	ligase activity, forming carbon-carbon bonds
NX819_12530	COG3854	ATPases associated with a variety of cellular activities
NX819_12540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NX819_12545	COG0006	proline dipeptidase activity
NX819_12550	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NX819_12560	COG3872	metal-dependent enzyme
NX819_12570	COG1752	Esterase of the alpha-beta hydrolase superfamily
NX819_12575	COG1321	iron dependent repressor
NX819_12580	COG0095	Lipoate-protein ligase
NX819_12585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NX819_12590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NX819_12595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NX819_12600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NX819_12605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NX819_12620	COG1396	sequence-specific DNA binding
NX819_12630	COG0681	Belongs to the peptidase S26 family
NX819_12655	COG4940	Competence protein ComGF
NX819_12665	COG4970	Tfp pilus assembly protein FimT
NX819_12670	COG4537	Required for transformation and DNA binding
NX819_12675	COG1459	type II secretion system
NX819_12680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NX819_12685	COG0517	IMP dehydrogenase activity
NX819_12690	COG0598	Magnesium transport protein CorA
NX819_12695	COG1253	flavin adenine dinucleotide binding
NX819_12700	COG1366	Belongs to the anti-sigma-factor antagonist family
NX819_12710	COG1393	Belongs to the ArsC family
NX819_12720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX819_12730	COG0011	TIGRFAM Protein of
NX819_12740	COG2866	Carboxypeptidase
NX819_12745	COG1368	sulfuric ester hydrolase activity
NX819_12750	COG1940	carbohydrate kinase activity
NX819_12755	COG4483	Protein conserved in bacteria
NX819_12760	COG0457	Tetratricopeptide repeat
NX819_12760	COG0705	Rhomboid family
NX819_12770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NX819_12780	COG0438	transferase activity, transferring glycosyl groups
NX819_12795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NX819_12800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NX819_12805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NX819_12810	COG0581	inorganic phosphate transmembrane transporter activity
NX819_12815	COG0573	inorganic phosphate transmembrane transporter activity
NX819_12820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NX819_12825	COG0768	penicillin binding
NX819_12830	COG0477	Major facilitator Superfamily
NX819_12835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NX819_12840	COG2839	Protein conserved in bacteria
NX819_12845	COG5521	maltodextrose utilization protein MalA
NX819_12850	COG1388	LysM domain
NX819_12855	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NX819_12860	COG4709	membrane
NX819_12865	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NX819_12870	COG0735	belongs to the Fur family
NX819_12875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX819_12885	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NX819_12890	COG0513	Belongs to the DEAD box helicase family
NX819_12900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NX819_12905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NX819_12910	COG2384	SAM-dependent methyltransferase
NX819_12915	COG2010	Cytochrome c
NX819_12920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NX819_12925	COG0358	DNA primase activity
NX819_12930	COG1671	Belongs to the UPF0178 family
NX819_12935	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NX819_12940	COG0517	IMP dehydrogenase activity
NX819_12945	COG0751	glycine-tRNA ligase activity
NX819_12950	COG0752	glycyl-tRNA synthetase alpha subunit
NX819_12955	COG1381	Involved in DNA repair and RecF pathway recombination
NX819_12965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NX819_12970	COG0295	cytidine deaminase activity
NX819_12975	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NX819_12980	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NX819_12985	COG1480	7TM receptor with intracellular HD hydrolase
NX819_12990	COG1702	phosphate starvation-inducible protein PhoH
NX819_12995	COG0561	phosphatase activity
NX819_13010	COG4864	UPF0365 protein
NX819_13015	COG1030	water channel activity
NX819_13020	COG1610	YqeY-like protein
NX819_13030	COG1283	sodium-dependent phosphate transmembrane transporter activity
NX819_13035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NX819_13040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NX819_13045	COG2264	protein methyltransferase activity
NX819_13050	COG0484	heat shock protein binding
NX819_13055	COG0443	Heat shock 70 kDa protein
NX819_13060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NX819_13065	COG1420	regulation of RNA biosynthetic process
NX819_13070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NX819_13075	COG0481	GTPase activity
NX819_13085	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX819_13090	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NX819_13095	COG0268	Binds directly to 16S ribosomal RNA
NX819_13100	COG1466	dna polymerase III delta subunit
NX819_13115	COG0658	competence protein
NX819_13115	COG2333	competence protein COMEC
NX819_13120	COG2131	deaminase
NX819_13125	COG1596	polysaccharide export
NX819_13125	COG1555	photosystem II stabilization
NX819_13130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NX819_13135	COG2226	methyltransferase
NX819_13140	COG0799	negative regulation of ribosome biogenesis
NX819_13145	COG1713	HD superfamily hydrolase involved in NAD metabolism
NX819_13150	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NX819_13155	COG1534	Rna-binding protein
NX819_13160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NX819_13165	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NX819_13170	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NX819_13180	COG2755	lipolytic protein G-D-S-L family
NX819_13185	COG3409	Peptidoglycan-binding domain 1 protein
NX819_13185	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX819_13190	COG0398	Pfam SNARE associated Golgi protein
NX819_13195	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NX819_13205	COG3209	COG3209 Rhs family protein
NX819_13235	COG0604	alcohol dehydrogenase
NX819_13245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NX819_13250	COG0798	PFAM Bile acid sodium symporter
NX819_13255	COG0346	lactoylglutathione lyase activity
NX819_13260	COG0640	Transcriptional regulator
NX819_13270	COG0457	Tetratricopeptide repeat
NX819_13280	COG0656	L-ascorbic acid biosynthetic process
NX819_13295	COG5444	nuclease activity
NX819_13305	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX819_13305	COG3409	Peptidoglycan-binding domain 1 protein
NX819_13365	COG3677	Transposase
NX819_13375	COG3209	COG3209 Rhs family protein
NX819_13415	COG0563	adenylate kinase activity
NX819_13430	COG2814	Major facilitator Superfamily
NX819_13435	COG1082	Xylose isomerase domain protein TIM barrel
NX819_13440	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_13445	COG1609	Transcriptional regulator
NX819_13450	COG1331	Highly conserved protein containing a thioredoxin domain
NX819_13455	COG0730	response to heat
NX819_13460	COG0425	Belongs to the sulfur carrier protein TusA family
NX819_13475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NX819_13475	COG0425	Belongs to the sulfur carrier protein TusA family
NX819_13480	COG2210	Belongs to the sulfur carrier protein TusA family
NX819_13485	COG1937	Protein conserved in bacteria
NX819_13495	COG0662	Cupin 2, conserved barrel domain protein
NX819_13510	COG4978	Transcriptional regulator
NX819_13510	COG0789	Transcriptional regulator
NX819_13515	COG2814	Major facilitator Superfamily
NX819_13520	COG0456	acetyltransferase
NX819_13525	COG1253	flavin adenine dinucleotide binding
NX819_13535	COG0697	spore germination
NX819_13540	COG0583	DNA-binding transcription factor activity
NX819_13545	COG2072	flavoprotein involved in K transport
NX819_13550	COG1230	cation diffusion facilitator family transporter
NX819_13555	COG1942	4-Oxalocrotonate Tautomerase
NX819_13560	COG0583	DNA-binding transcription factor activity
NX819_13570	COG1114	Component of the transport system for branched-chain amino acids
NX819_13575	COG1687	branched-chain amino acid
NX819_13580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NX819_13585	COG1522	sequence-specific DNA binding
NX819_13595	COG2124	cytochrome p450
NX819_13610	COG1335	isochorismatase
NX819_13625	COG2318	DinB family
NX819_13635	COG2070	2-Nitropropane dioxygenase
NX819_13640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NX819_13660	COG3443	Belongs to the bacterial solute-binding protein 9 family
NX819_13665	COG1595	DNA-templated transcription, initiation
NX819_13675	COG2851	Citrate transporter
NX819_13680	COG0583	DNA-binding transcription factor activity
NX819_13685	COG2828	Protein conserved in bacteria
NX819_13690	COG3409	Peptidoglycan-binding domain 1 protein
NX819_13695	COG5566	PFAM Mor transcription activator
NX819_13700	COG0596	Alpha beta hydrolase
NX819_13705	COG4991	sh3 domain protein
NX819_13710	COG4991	sh3 domain protein
NX819_13720	COG0346	lactoylglutathione lyase activity
NX819_13730	COG5577	PFAM Coat F domain
NX819_13735	COG1063	alcohol dehydrogenase
NX819_13745	COG5577	PFAM Coat F domain
NX819_13750	COG0789	Transcriptional regulator
NX819_13760	COG1064	alcohol dehydrogenase
NX819_13765	COG0693	protein deglycase activity
NX819_13770	COG1621	beta-fructofuranosidase activity
NX819_13780	COG3716	PTS system mannose fructose sorbose family IID component
NX819_13785	COG3715	PTS system
NX819_13790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_13795	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX819_13800	COG3933	PFAM sigma-54 factor interaction domain-containing protein
NX819_13800	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NX819_13810	COG1113	amino acid transport
NX819_13815	COG1280	lysine exporter protein (LysE YggA)
NX819_13820	COG1378	Sugar-specific transcriptional regulator TrmB
NX819_13825	COG1595	DNA-templated transcription, initiation
NX819_13835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NX819_13835	COG2755	lipolytic protein G-D-S-L family
NX819_13845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX819_13845	COG2124	cytochrome p450
NX819_13850	COG1309	transcriptional regulator
NX819_13855	COG2226	methyltransferase
NX819_13870	COG2116	formate transmembrane transporter activity
NX819_13875	COG5609	conserved protein (DUF2294)
NX819_13880	COG3383	formate dehydrogenase (NAD+) activity
NX819_13885	COG2427	Protein of unknown function (DUF1641)
NX819_13895	COG0626	cystathionine gamma-synthase activity
NX819_13900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NX819_13905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NX819_13910	COG2226	methyltransferase
NX819_13925	COG0768	penicillin binding
NX819_13930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NX819_13935	COG0572	uridine kinase
NX819_13940	COG0826	peptidase U32
NX819_13945	COG0826	peptidase U32
NX819_13950	COG4122	O-methyltransferase activity
NX819_13955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NX819_13960	COG3906	Belongs to the UPF0473 family
NX819_13965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NX819_13970	COG4472	Bacterial protein of unknown function (DUF965)
NX819_13975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NX819_13980	COG0628	permease
NX819_13985	COG1126	abc transporter atp-binding protein
NX819_13990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX819_13995	COG0765	amino acid transport
NX819_14000	COG0765	amino acid transport
NX819_14015	COG3881	PFAM PRC-barrel domain
NX819_14020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NX819_14025	COG0457	Tetratricopeptide repeat
NX819_14030	COG0482	sulfurtransferase activity
NX819_14035	COG1104	cysteine desulfurase activity
NX819_14040	COG1959	2 iron, 2 sulfur cluster binding
NX819_14045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NX819_14050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NX819_14060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NX819_14065	COG0124	histidyl-tRNA synthetase
NX819_14075	COG4991	sh3 domain protein
NX819_14075	COG3103	Sh3 type 3 domain protein
NX819_14075	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX819_14080	COG1490	D-aminoacyl-tRNA deacylase activity
NX819_14085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NX819_14090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NX819_14095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NX819_14095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NX819_14100	COG5416	Lipopolysaccharide assembly protein A domain
NX819_14105	COG0490	domain, Protein
NX819_14110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NX819_14110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NX819_14120	COG2244	polysaccharide biosynthetic process
NX819_14125	COG2323	membrane
NX819_14135	COG1862	Preprotein translocase
NX819_14140	COG0343	queuine tRNA-ribosyltransferase activity
NX819_14145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NX819_14155	COG2255	four-way junction helicase activity
NX819_14160	COG0632	four-way junction helicase activity
NX819_14170	COG2814	Major facilitator Superfamily
NX819_14175	COG0673	inositol 2-dehydrogenase activity
NX819_14180	COG2112	serine threonine protein kinase
NX819_14200	COG1115	amino acid carrier protein
NX819_14205	COG0217	transcriptional regulatory protein
NX819_14215	COG1388	LysM domain
NX819_14220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NX819_14225	COG0157	Belongs to the NadC ModD family
NX819_14230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NX819_14235	COG1104	cysteine desulfurase activity
NX819_14240	COG1827	regulation of RNA biosynthetic process
NX819_14245	COG0077	Prephenate dehydratase
NX819_14250	COG4492	Belongs to the UPF0735 family
NX819_14255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NX819_14260	COG3290	protein histidine kinase activity
NX819_14270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NX819_14275	COG2868	ribosomal protein
NX819_14280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NX819_14285	COG1994	Peptidase M50
NX819_14290	COG0739	heme binding
NX819_14295	COG2894	cell division
NX819_14300	COG0850	regulation of cytokinetic process
NX819_14305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NX819_14315	COG1077	Cell shape determining protein MreB Mrl
NX819_14320	COG2003	Belongs to the UPF0758 family
NX819_14325	COG0424	maF-like protein
NX819_14335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NX819_14340	COG0285	dihydrofolate synthase activity
NX819_14345	COG0525	valine-tRNA ligase activity
NX819_14355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NX819_14360	COG1388	LysM domain
NX819_14365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NX819_14370	COG0113	porphobilinogen synthase activity
NX819_14375	COG1587	Uroporphyrinogen-III synthase
NX819_14380	COG0181	hydroxymethylbilane synthase activity
NX819_14385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NX819_14390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NX819_14400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NX819_14405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NX819_14410	COG1067	ATP-dependent peptidase activity
NX819_14410	COG0470	DNA polymerase III
NX819_14415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NX819_14420	COG0544	peptidyl-prolyl cis-trans isomerase activity
NX819_14425	COG1477	protein flavinylation
NX819_14425	COG0457	Tetratricopeptide repeat
NX819_14430	COG0066	3-isopropylmalate dehydratase activity
NX819_14435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NX819_14440	COG0473	3-isopropylmalate dehydrogenase activity
NX819_14445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NX819_14450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NX819_14455	COG0440	acetolactate synthase activity
NX819_14460	COG0028	Belongs to the TPP enzyme family
NX819_14470	COG0454	-acetyltransferase
NX819_14475	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NX819_14485	COG0622	Phosphoesterase
NX819_14490	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NX819_14495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NX819_14500	COG5401	PFAM Sporulation and spore germination
NX819_14505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NX819_14510	COG1846	Transcriptional regulator
NX819_14520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX819_14535	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX819_14535	COG3409	Peptidoglycan-binding domain 1 protein
NX819_14595	COG1388	LysM domain
NX819_14595	COG0791	NLP P60 protein
NX819_14600	COG5280	Phage tail tape measure protein TP901
NX819_14600	COG3953	SLT domain
NX819_14675	COG5484	DNA packaging
NX819_14700	COG1595	DNA-templated transcription, initiation
NX819_14760	COG1484	DNA-dependent DNA replication
NX819_14765	COG3935	DnaD domain protein
NX819_14775	COG5377	YqaJ viral recombinase family
NX819_14815	COG3620	sequence-specific DNA binding
NX819_14825	COG2856	Zn peptidase
NX819_14830	COG2197	response regulator
NX819_14835	COG0824	Thioesterase
NX819_14840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NX819_14845	COG1053	succinate dehydrogenase
NX819_14850	COG2009	succinate dehydrogenase
NX819_14855	COG1719	4-vinyl reductase, 4VR
NX819_14860	COG0527	aspartate kinase activity
NX819_14865	COG0322	excinuclease ABC activity
NX819_14870	COG3118	belongs to the thioredoxin family
NX819_14875	COG3534	alpha-L-arabinofuranosidase
NX819_14880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NX819_14885	COG2086	electron transfer activity
NX819_14890	COG1024	Enoyl-CoA hydratase
NX819_14895	COG1309	transcriptional regulator
NX819_14900	COG0318	PFAM AMP-dependent synthetase and ligase
NX819_14905	COG3766	membrane
NX819_14910	COG1193	negative regulation of DNA recombination
NX819_14915	COG1796	DNA polymerase
NX819_14915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NX819_14920	COG1286	toxin biosynthetic process
NX819_14925	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NX819_14930	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NX819_14935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX819_14935	COG0072	phenylalanine-tRNA ligase activity
NX819_14940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NX819_14950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NX819_14960	COG3835	regulator
NX819_14965	COG0277	FAD linked oxidase domain protein
NX819_14970	COG0247	lactate metabolic process
NX819_14975	COG0346	lactoylglutathione lyase activity
NX819_14985	COG1966	Carbon starvation protein
NX819_14990	COG3534	alpha-L-arabinofuranosidase
NX819_14995	COG0395	ABC-type sugar transport system, permease component
NX819_15000	COG1175	transmembrane transport
NX819_15005	COG1653	transport
NX819_15010	COG0371	Dehydrogenase
NX819_15015	COG0647	UMP catabolic process
NX819_15020	COG0235	Class ii aldolase
NX819_15025	COG1069	ribulokinase activity
NX819_15030	COG2160	L-arabinose isomerase activity
NX819_15035	COG3507	Belongs to the glycosyl hydrolase 43 family
NX819_15040	COG1363	Peptidase, m42
NX819_15050	COG3326	Membrane
NX819_15055	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NX819_15060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NX819_15065	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NX819_15075	COG1346	cytolysis
NX819_15080	COG1380	Effector of murein hydrolase LrgA
NX819_15085	COG3279	Response regulator of the LytR AlgR family
NX819_15090	COG3275	phosphorelay sensor kinase activity
NX819_15095	COG1011	Hydrolase
NX819_15100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NX819_15110	COG0398	Pfam SNARE associated Golgi protein
NX819_15115	COG1484	DNA-dependent DNA replication
NX819_15120	COG3611	Membrane attachment protein
NX819_15125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NX819_15130	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NX819_15135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NX819_15140	COG1733	regulation of RNA biosynthetic process
NX819_15145	COG2814	Major facilitator Superfamily
NX819_15150	COG0656	L-ascorbic acid biosynthetic process
NX819_15155	COG0237	dephospho-CoA kinase activity
NX819_15160	COG1971	Probably functions as a manganese efflux pump
NX819_15165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NX819_15170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NX819_15170	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NX819_15175	COG5002	protein histidine kinase activity
NX819_15180	COG0745	RESPONSE REGULATOR receiver
NX819_15185	COG0039	L-malate dehydrogenase activity
NX819_15190	COG0538	isocitrate dehydrogenase activity
NX819_15195	COG0372	Belongs to the citrate synthase family
NX819_15200	COG2707	UPF0756 membrane protein
NX819_15205	COG0628	permease
NX819_15210	COG3030	protein affecting phage T7 exclusion by the F plasmid
NX819_15215	COG0469	pyruvate kinase activity
NX819_15220	COG0205	6-phosphofructokinase activity
NX819_15225	COG0825	malonyl-CoA metabolic process
NX819_15230	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NX819_15235	COG0281	malic enzyme
NX819_15240	COG0587	DNA-directed DNA polymerase activity
NX819_15260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NX819_15270	COG4109	DRTGG domain
NX819_15275	COG0730	response to heat
NX819_15280	COG1473	amidohydrolase
NX819_15285	COG0196	riboflavin kinase activity
NX819_15290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX819_15295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NX819_15300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX819_15305	COG1126	abc transporter atp-binding protein
NX819_15310	COG0765	amino acid transport
NX819_15315	COG0765	amino acid transport
NX819_15320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX819_15325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX819_15330	COG0454	-acetyltransferase
NX819_15335	COG0583	DNA-binding transcription factor activity
NX819_15340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NX819_15345	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_15355	COG0165	Argininosuccinate lyase
NX819_15360	COG0137	argininosuccinate synthase activity
NX819_15365	COG0521	Mo-molybdopterin cofactor biosynthetic process
NX819_15370	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NX819_15380	COG0827	DNA restriction-modification system
NX819_15385	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NX819_15390	COG3874	Sporulation protein YtfJ
NX819_15400	COG1714	RDD family
NX819_15405	COG0616	signal peptide processing
NX819_15410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NX819_15415	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NX819_15420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NX819_15430	COG0301	tRNA thio-modification
NX819_15435	COG1104	cysteine desulfurase activity
NX819_15440	COG1114	Component of the transport system for branched-chain amino acids
NX819_15445	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NX819_15450	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NX819_15455	COG1309	transcriptional regulator
NX819_15460	COG1956	GAF domain-containing protein
NX819_15465	COG2203	Gaf domain
NX819_15465	COG2199	diguanylate cyclase activity
NX819_15470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NX819_15475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NX819_15480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NX819_15485	COG0454	-acetyltransferase
NX819_15490	COG0517	IMP dehydrogenase activity
NX819_15495	COG0123	including yeast histone deacetylase and acetoin utilization protein
NX819_15500	COG1360	Flagellar Motor Protein
NX819_15505	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NX819_15510	COG1609	Transcriptional regulator
NX819_15515	COG1605	Chorismate mutase
NX819_15515	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NX819_15520	COG3118	belongs to the thioredoxin family
NX819_15525	COG4980	gas vesicle protein
NX819_15530	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NX819_15535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NX819_15540	COG1674	ftsk spoiiie
NX819_15545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX819_15550	COG4848	Belongs to the UPF0354 family
NX819_15555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX819_15570	COG1363	Peptidase, m42
NX819_15575	COG5584	Small secreted protein
NX819_15580	COG0281	malic enzyme
NX819_15585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX819_15590	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NX819_15600	COG0510	thiamine kinase activity
NX819_15605	COG1523	belongs to the glycosyl hydrolase 13 family
NX819_15610	COG1597	lipid kinase activity
NX819_15620	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NX819_15625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NX819_15630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX819_15635	COG2252	PERMEase
NX819_15640	COG4473	ABC transporter
NX819_15645	COG1131	(ABC) transporter
NX819_15650	COG1349	DNA-binding transcription factor activity
NX819_15655	COG1187	pseudouridine synthase activity
NX819_15660	COG2244	polysaccharide biosynthetic process
NX819_15665	COG2081	HI0933 family
NX819_15670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NX819_15680	COG5578	integral membrane protein
NX819_15685	COG0673	inositol 2-dehydrogenase activity
NX819_15690	COG1653	transport
NX819_15695	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NX819_15700	COG4209	transmembrane transport
NX819_15705	COG2207	Transcriptional regulator
NX819_15710	COG1653	transport
NX819_15715	COG0395	ABC-type sugar transport system, permease component
NX819_15720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX819_15725	COG2124	cytochrome p450
NX819_15730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NX819_15740	COG0156	8-amino-7-oxononanoate synthase activity
NX819_15745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NX819_15755	COG1073	alpha beta
NX819_15760	COG1609	Transcriptional regulator
NX819_15765	COG1653	transport
NX819_15770	COG1175	transmembrane transport
NX819_15775	COG0395	ABC-type sugar transport system, permease component
NX819_15780	COG1486	melibiose metabolic process
NX819_15785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NX819_15790	COG0495	leucyl-tRNA aminoacylation
NX819_15800	COG2202	Pas domain
NX819_15800	COG1366	Belongs to the anti-sigma-factor antagonist family
NX819_15805	COG2814	Major facilitator Superfamily
NX819_15810	COG2433	Pfam Transposase IS66
NX819_15815	COG0577	efflux transmembrane transporter activity
NX819_15820	COG1136	(ABC) transporter
NX819_15825	COG2205	protein histidine kinase activity
NX819_15830	COG0745	RESPONSE REGULATOR receiver
NX819_15835	COG0577	efflux transmembrane transporter activity
NX819_15840	COG1136	(ABC) transporter
NX819_15855	COG1131	(ABC) transporter
NX819_15860	COG1725	Transcriptional regulator
NX819_15875	COG1242	4 iron, 4 sulfur cluster binding
NX819_15880	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NX819_15890	COG2267	carboxylic ester hydrolase activity
NX819_15895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NX819_15900	COG1113	amino acid transport
NX819_15905	COG0367	asparagine synthase
NX819_15910	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NX819_15915	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NX819_15925	COG1506	peptidase
NX819_15930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NX819_15935	COG1116	anion transmembrane transporter activity
NX819_15940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NX819_15945	COG0494	nUDIX hydrolase
NX819_15950	COG4824	toxin secretion phage lysis holin
NX819_15955	COG0783	Belongs to the Dps family
NX819_15970	COG1854	S-ribosylhomocysteine lyase activity
NX819_15975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NX819_15980	COG0288	reversible hydration of carbon dioxide
NX819_15985	COG0254	rRNA binding
NX819_15990	COG1271	oxidase subunit
NX819_15995	COG1294	oxidase, subunit
NX819_16005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NX819_16010	COG1321	iron dependent repressor
NX819_16010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NX819_16015	COG1121	(ABC) transporter
NX819_16020	COG0803	Belongs to the bacterial solute-binding protein 9 family
NX819_16025	COG4948	Mandelate Racemase Muconate Lactonizing
NX819_16030	COG0318	PFAM AMP-dependent synthetase and ligase
NX819_16035	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NX819_16040	COG0596	Alpha beta hydrolase
NX819_16045	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NX819_16050	COG1169	isochorismate synthase
NX819_16055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX819_16060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NX819_16065	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NX819_16070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX819_16075	COG0438	transferase activity, transferring glycosyl groups
NX819_16085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NX819_16090	COG0438	transferase activity, transferring glycosyl groups
NX819_16095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NX819_16100	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NX819_16105	COG0058	SHG alpha-glucan phosphorylase activity
NX819_16110	COG0297	glycogen (starch) synthase activity
NX819_16115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NX819_16120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NX819_16125	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NX819_16250	COG3859	Proton-coupled thiamine transporter YuaJ
NX819_16255	COG1247	-acetyltransferase
NX819_16260	COG2268	Band 7 protein
NX819_16265	COG1585	Membrane protein implicated in regulation of membrane protease activity
NX819_16270	COG2318	DinB family
NX819_16280	COG1454	alcohol dehydrogenase
NX819_16285	COG1012	belongs to the aldehyde dehydrogenase family
NX819_16290	COG1510	regulation of RNA biosynthetic process
NX819_16300	COG0569	domain protein
NX819_16305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NX819_16310	COG4682	membrane
NX819_16315	COG1705	Flagellar rod assembly protein muramidase FlgJ
NX819_16320	COG0477	Major facilitator Superfamily
NX819_16325	COG5553	Cysteine dioxygenase type I
NX819_16335	COG1968	undecaprenyl-diphosphatase activity
NX819_16340	COG0628	permease
NX819_16345	COG0673	inositol 2-dehydrogenase activity
NX819_16350	COG4806	L-rhamnose isomerase
NX819_16355	COG3254	rhamnose metabolic process
NX819_16360	COG1070	Carbohydrate kinase
NX819_16365	COG1349	DNA-binding transcription factor activity
NX819_16370	COG3347	Dehydrogenase
NX819_16370	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_16375	COG0840	transmembrane signaling receptor activity
NX819_16380	COG0840	transmembrane signaling receptor activity
NX819_16385	COG0840	transmembrane signaling receptor activity
NX819_16390	COG0840	transmembrane signaling receptor activity
NX819_16405	COG0432	Pfam Uncharacterised protein family UPF0047
NX819_16415	COG0366	Alpha amylase catalytic
NX819_16420	COG1253	flavin adenine dinucleotide binding
NX819_16425	COG2738	Putative neutral zinc metallopeptidase
NX819_16440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NX819_16455	COG0166	Belongs to the GPI family
NX819_16460	COG1979	alcohol dehydrogenase
NX819_16465	COG1979	alcohol dehydrogenase
NX819_16470	COG2155	Conserved Protein
NX819_16475	COG1098	S1 RNA binding domain
NX819_16480	COG0436	Aminotransferase
NX819_16485	COG1522	sequence-specific DNA binding
NX819_16490	COG2267	carboxylic ester hydrolase activity
NX819_16500	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NX819_16505	COG2205	protein histidine kinase activity
NX819_16515	COG5018	Exonuclease
NX819_16525	COG2814	Major facilitator Superfamily
NX819_16530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NX819_16535	COG3011	Protein conserved in bacteria
NX819_16545	COG3290	protein histidine kinase activity
NX819_16550	COG4565	transcriptional regulatory protein
NX819_16555	COG1744	ABC transporter substrate-binding protein PnrA-like
NX819_16560	COG3845	ABC transporter
NX819_16565	COG4603	Belongs to the binding-protein-dependent transport system permease family
NX819_16570	COG1079	Belongs to the binding-protein-dependent transport system permease family
NX819_16575	COG3493	citrate carrier protein
NX819_16585	COG2111	Na H antiporter
NX819_16585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NX819_16590	COG2111	Na H antiporter
NX819_16595	COG1006	Multisubunit Na H antiporter MnhC subunit
NX819_16600	COG0651	ATP synthesis coupled electron transport
NX819_16605	COG1863	multisubunit Na H antiporter MnhE subunit
NX819_16610	COG2212	antiporter activity
NX819_16615	COG1320	monovalent cation:proton antiporter activity
NX819_16620	COG2050	protein possibly involved in aromatic compounds catabolism
NX819_16625	COG2197	response regulator
NX819_16640	COG0142	geranyltranstransferase activity
NX819_16660	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NX819_16665	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NX819_16670	COG1335	isochorismatase
NX819_16675	COG5506	Protein of unknown function (DUF1694)
NX819_16690	COG0628	permease
NX819_16705	COG1418	mRNA catabolic process
NX819_16710	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_16720	COG1511	domain protein
NX819_16725	COG1674	ftsk spoiiie
NX819_16725	COG0433	COG0433 Predicted ATPase
NX819_16730	COG4499	WXG100 protein secretion system (Wss), protein YukC
NX819_16735	COG5417	Belongs to the EsaB family
NX819_16740	COG4842	Belongs to the WXG100 family
NX819_16745	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NX819_16745	COG2508	Transcriptional regulator
NX819_16750	COG0686	Belongs to the AlaDH PNT family
NX819_16755	COG5634	Uncharacterized conserved protein (DUF2278)
NX819_16760	COG3251	PFAM MbtH domain protein
NX819_16765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_16770	COG1535	isochorismatase
NX819_16770	COG3433	isochorismatase activity
NX819_16775	COG1021	2,3-dihydroxybenzoate-AMP ligase
NX819_16780	COG1169	isochorismate synthase
NX819_16785	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_16790	COG2819	hydrolase of the alpha beta superfamily
NX819_16795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NX819_16800	COG1268	BioY protein
NX819_16805	COG2056	Na+-H+ antiporter family
NX819_16810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NX819_16815	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NX819_16820	COG3584	3D domain protein
NX819_16835	COG1252	NADH dehydrogenase
NX819_16840	COG0492	ferredoxin-NADP+ reductase activity
NX819_16850	COG0516	GMP reductase activity
NX819_16855	COG2808	Putative FMN-binding domain
NX819_16860	COG0456	acetyltransferase
NX819_16865	COG0316	Belongs to the HesB IscA family
NX819_16870	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NX819_16875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NX819_16880	COG4844	belongs to the
NX819_16885	COG1252	NADH dehydrogenase
NX819_16890	COG4837	Protein of unknown function (DUF1462)
NX819_16895	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NX819_16900	COG1506	peptidase
NX819_16900	COG4946	Tricorn protease homolog
NX819_16900	COG0823	Involved in the tonB-independent uptake of proteins
NX819_16905	COG0083	homoserine kinase activity
NX819_16910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NX819_16915	COG0460	homoserine dehydrogenase
NX819_16920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NX819_16925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NX819_16930	COG0647	UMP catabolic process
NX819_16935	COG2445	Protein of unknown function DUF86
NX819_16940	COG4470	Protein conserved in bacteria
NX819_16950	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NX819_16955	COG0739	heme binding
NX819_16965	COG3377	Domain of unknown function (DUF1805)
NX819_16970	COG0737	Belongs to the 5'-nucleotidase family
NX819_16975	COG0730	response to heat
NX819_16980	COG1801	Protein of unknown function DUF72
NX819_16990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NX819_16995	COG2508	Transcriptional regulator
NX819_17000	COG2233	PERMEase
NX819_17005	COG2233	PERMEase
NX819_17010	COG3648	Uricase
NX819_17010	COG3195	allantoin biosynthetic process
NX819_17015	COG2351	hydroxyisourate hydrolase activity
NX819_17025	COG2080	2 iron, 2 sulfur cluster binding
NX819_17030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NX819_17035	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NX819_17040	COG2068	MobA-Related Protein
NX819_17045	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NX819_17050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NX819_17055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX819_17065	COG2356	endonuclease I
NX819_17070	COG3842	ATPase activity
NX819_17075	COG2188	Transcriptional regulator
NX819_17080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX819_17085	COG0395	ABC-type sugar transport system, permease component
NX819_17090	COG1175	transmembrane transport
NX819_17095	COG1653	transport
NX819_17100	COG2222	sugar isomerase
NX819_17105	COG0322	excinuclease ABC activity
NX819_17110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX819_17125	COG0346	lactoylglutathione lyase activity
NX819_17130	COG0640	Transcriptional regulator
NX819_17135	COG0719	Fe-S assembly protein
NX819_17140	COG0822	iron-sulfur transferase activity
NX819_17145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NX819_17150	COG0719	Fe-S assembly protein
NX819_17155	COG0396	ATPase activity
NX819_17165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NX819_17170	COG1464	Belongs to the NlpA lipoprotein family
NX819_17175	COG2011	ABC-type metal ion transport system permease component
NX819_17180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NX819_17190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX819_17195	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NX819_17205	COG0509	glycine decarboxylation via glycine cleavage system
NX819_17210	COG1393	Belongs to the ArsC family
NX819_17215	COG1960	acyl-CoA dehydrogenase activity
NX819_17220	COG0183	Belongs to the thiolase family
NX819_17225	COG1250	3-hydroxyacyl-CoA dehydrogenase
NX819_17225	COG1024	Enoyl-CoA hydratase
NX819_17235	COG0506	proline dehydrogenase activity
NX819_17245	COG5577	PFAM Coat F domain
NX819_17250	COG1846	Transcriptional regulator
NX819_17255	COG0477	Major facilitator Superfamily
NX819_17260	COG1942	4-Oxalocrotonate Tautomerase
NX819_17270	COG0583	DNA-binding transcription factor activity
NX819_17280	COG1120	ATPase activity
NX819_17295	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_17300	COG0783	Belongs to the Dps family
NX819_17305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX819_17310	COG0745	RESPONSE REGULATOR receiver
NX819_17315	COG2770	Histidine kinase
NX819_17315	COG2205	protein histidine kinase activity
NX819_17325	COG1309	transcriptional regulator
NX819_17330	COG0114	fumarate hydratase activity
NX819_17340	COG0697	spore germination
NX819_17345	COG0814	amino acid
NX819_17355	COG2197	response regulator
NX819_17360	COG4585	Histidine kinase
NX819_17365	COG4758	membrane
NX819_17370	COG3595	metallopeptidase activity
NX819_17375	COG1842	Phage shock protein A
NX819_17380	COG4758	membrane
NX819_17385	COG2814	Major facilitator Superfamily
NX819_17390	COG2096	Adenosyltransferase
NX819_17395	COG1120	ATPase activity
NX819_17400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX819_17405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX819_17410	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_17415	COG3386	PFAM SMP-30 Gluconolaconase
NX819_17420	COG2205	protein histidine kinase activity
NX819_17425	COG0745	RESPONSE REGULATOR receiver
NX819_17435	COG1191	sigma factor activity
NX819_17445	COG2140	Oxalate decarboxylase
NX819_17455	COG0577	efflux transmembrane transporter activity
NX819_17460	COG1136	(ABC) transporter
NX819_17465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX819_17470	COG1120	ATPase activity
NX819_17475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX819_17480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX819_17485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX819_17490	COG0531	amino acid
NX819_17500	COG1988	membrane-bound metal-dependent
NX819_17505	COG1368	sulfuric ester hydrolase activity
NX819_17510	COG1910	domain protein
NX819_17515	COG0725	ABC transporter, periplasmic molybdate-binding protein
NX819_17520	COG4149	molybdate abc transporter
NX819_17525	COG0656	L-ascorbic acid biosynthetic process
NX819_17535	COG0025	NhaP-type Na H and K H
NX819_17540	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NX819_17545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX819_17550	COG3973	AAA domain
NX819_17555	COG2860	membrane
NX819_17560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NX819_17565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NX819_17570	COG2217	Heavy metal translocating P-type atpase
NX819_17575	COG2217	Heavy metal translocating P-type atpase
NX819_17580	COG2608	mercury ion transmembrane transporter activity
NX819_17585	COG1937	Protein conserved in bacteria
NX819_17590	COG0673	inositol 2-dehydrogenase activity
NX819_17595	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NX819_17610	COG2076	Multidrug Resistance protein
NX819_17615	COG1309	transcriptional regulator
NX819_17620	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_17630	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NX819_17635	COG0557	exoribonuclease II activity
NX819_17640	COG1647	Serine aminopeptidase, S33
NX819_17645	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NX819_17650	COG0596	Alpha beta hydrolase
NX819_17655	COG1476	TRANSCRIPTIONal
NX819_17660	COG1396	sequence-specific DNA binding
NX819_17665	COG1396	sequence-specific DNA binding
NX819_17670	COG1733	regulation of RNA biosynthetic process
NX819_17675	COG0840	transmembrane signaling receptor activity
NX819_17680	COG1174	glycine betaine transport
NX819_17685	COG1732	Glycine betaine
NX819_17690	COG1174	glycine betaine transport
NX819_17695	COG0517	IMP dehydrogenase activity
NX819_17695	COG1125	glycine betaine transport
NX819_17700	COG1510	regulation of RNA biosynthetic process
NX819_17720	COG5658	integral membrane protein
NX819_17725	COG0640	Transcriptional regulator
NX819_17730	COG1174	glycine betaine transport
NX819_17735	COG1732	Glycine betaine
NX819_17740	COG1174	glycine betaine transport
NX819_17745	COG0517	IMP dehydrogenase activity
NX819_17745	COG1125	glycine betaine transport
NX819_17750	COG1510	regulation of RNA biosynthetic process
NX819_17755	COG2095	MarC family integral membrane protein
NX819_17765	COG3064	Membrane
NX819_17770	COG4640	response to antibiotic
NX819_17775	COG0456	acetyltransferase
NX819_17780	COG0148	phosphopyruvate hydratase activity
NX819_17785	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NX819_17790	COG0149	triose-phosphate isomerase activity
NX819_17795	COG0126	phosphoglycerate kinase activity
NX819_17800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NX819_17805	COG2390	Transcriptional regulator
NX819_17810	COG2814	Major facilitator Superfamily
NX819_17815	COG1609	Transcriptional regulator
NX819_17820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX819_17825	COG0583	DNA-binding transcription factor activity
NX819_17830	COG0697	spore germination
NX819_17835	COG1113	amino acid transport
NX819_17840	COG3858	chitin binding
NX819_17845	COG1556	Lactate utilization protein
NX819_17850	COG1139	Iron-sulfur cluster binding protein
NX819_17855	COG0247	lactate metabolic process
NX819_17860	COG2197	response regulator
NX819_17865	COG4585	Histidine kinase
NX819_17870	COG0842	Transport permease protein
NX819_17875	COG1131	(ABC) transporter
NX819_17880	COG0596	Alpha beta hydrolase
NX819_17885	COG2208	phosphoserine phosphatase activity
NX819_17890	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NX819_17895	COG1874	Beta-galactosidase
NX819_17900	COG3833	ABC-type maltose transport systems, permease component
NX819_17905	COG1175	transmembrane transport
NX819_17910	COG2182	Extracellular solute-binding protein
NX819_17915	COG1609	Transcriptional regulator
NX819_17920	COG2186	Transcriptional regulator
NX819_17925	COG1620	l-lactate permease
NX819_17930	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NX819_17940	COG5039	Polysaccharide pyruvyl transferase
NX819_17945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NX819_17950	COG0110	maltose O-acetyltransferase activity
NX819_17955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NX819_17960	COG2244	polysaccharide biosynthetic process
NX819_17965	COG1216	Glycosyl transferase, family 2
NX819_17970	COG5039	Polysaccharide pyruvyl transferase
NX819_17975	COG1216	Glycosyl transferase, family 2
NX819_17985	COG0438	transferase activity, transferring glycosyl groups
NX819_17990	COG1215	transferase activity, transferring glycosyl groups
NX819_17995	COG0438	transferase activity, transferring glycosyl groups
NX819_18000	COG1086	Polysaccharide biosynthesis protein
NX819_18005	COG0489	protein tyrosine kinase activity
NX819_18010	COG3944	biosynthesis protein
NX819_18015	COG1396	sequence-specific DNA binding
NX819_18020	COG2272	Belongs to the type-B carboxylesterase lipase family
NX819_18030	COG3479	Phenolic acid decarboxylase
NX819_18045	COG1794	racemase activity, acting on amino acids and derivatives
NX819_18050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NX819_18055	COG1621	beta-fructofuranosidase activity
NX819_18060	COG1621	beta-fructofuranosidase activity
NX819_18065	COG0531	amino acid
NX819_18070	COG1309	transcriptional regulator
NX819_18075	COG2076	Multidrug Resistance protein
NX819_18080	COG2076	Multidrug Resistance protein
NX819_18090	COG0277	FAD linked oxidase domain protein
NX819_18095	COG3621	Patatin-like phospholipase
NX819_18105	COG0740	serine-type endopeptidase activity
NX819_18110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NX819_18115	COG0366	Alpha amylase catalytic
NX819_18120	COG1554	hydrolase, family 65, central catalytic
NX819_18125	COG5521	maltodextrose utilization protein MalA
NX819_18130	COG3833	ABC-type maltose transport systems, permease component
NX819_18135	COG1175	transmembrane transport
NX819_18140	COG2182	Extracellular solute-binding protein
NX819_18145	COG0366	Alpha amylase catalytic
NX819_18150	COG1609	Transcriptional regulator
NX819_18155	COG1611	Belongs to the LOG family
NX819_18160	COG1694	Mazg nucleotide pyrophosphohydrolase
NX819_18165	COG0659	secondary active sulfate transmembrane transporter activity
NX819_18170	COG0288	reversible hydration of carbon dioxide
NX819_18175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NX819_18180	COG0577	efflux transmembrane transporter activity
NX819_18185	COG1136	(ABC) transporter
NX819_18190	COG5002	protein histidine kinase activity
NX819_18195	COG0745	RESPONSE REGULATOR receiver
NX819_18205	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NX819_18210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX819_18215	COG1481	regulation of sporulation
NX819_18220	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NX819_18225	COG1660	Displays ATPase and GTPase activities
NX819_18230	COG1051	belongs to the nudix hydrolase family
NX819_18235	COG0492	ferredoxin-NADP+ reductase activity
NX819_18240	COG3883	PFAM NLP P60 protein
NX819_18240	COG0791	NLP P60 protein
NX819_18245	COG0457	Tetratricopeptide repeat
NX819_18250	COG1132	(ABC) transporter
NX819_18270	COG0140	phosphoribosyl-ATP diphosphatase activity
NX819_18270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NX819_18275	COG0107	imidazoleglycerol-phosphate synthase activity
NX819_18280	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NX819_18285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NX819_18290	COG0131	Imidazoleglycerol-phosphate dehydratase
NX819_18295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NX819_18300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NX819_18305	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NX819_18310	COG4990	cell redox homeostasis
NX819_18315	COG5297	Belongs to the glycosyl hydrolase family 6
NX819_18320	COG0110	maltose O-acetyltransferase activity
NX819_18325	COG0546	phosphoglycolate phosphatase activity
NX819_18330	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NX819_18335	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NX819_18340	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NX819_18345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NX819_18350	COG0363	glucosamine-6-phosphate deaminase activity
NX819_18355	COG2188	Transcriptional regulator
NX819_18360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NX819_18365	COG1846	Transcriptional regulator
NX819_18370	COG2124	cytochrome p450
NX819_18380	COG1846	Transcriptional regulator
NX819_18385	COG2814	Major facilitator Superfamily
NX819_18390	COG1950	PFAM Membrane protein of
NX819_18395	COG1983	PspC domain protein
NX819_18400	COG3595	metallopeptidase activity
NX819_18420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NX819_18425	COG0556	nucleotide-excision repair
NX819_18430	COG4897	Protein conserved in bacteria
NX819_18435	COG3848	Pyruvate phosphate dikinase
NX819_18435	COG0574	Belongs to the PEP-utilizing enzyme family
NX819_18440	COG1309	transcriptional regulator
NX819_18445	COG2814	Major facilitator Superfamily
NX819_18450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX819_18460	COG0793	Belongs to the peptidase S41A family
NX819_18460	COG3409	Peptidoglycan-binding domain 1 protein
NX819_18465	COG2177	Part of the ABC transporter FtsEX involved in
NX819_18470	COG2884	Cell division ATP-binding protein ftsE
NX819_18475	COG2010	Cytochrome c
NX819_18480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX819_18490	COG0653	protein targeting
NX819_18495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NX819_18510	COG1516	flagellar protein fliS
NX819_18515	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NX819_18520	COG1334	flagellar protein FlaG
NX819_18525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NX819_18530	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NX819_18535	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NX819_18545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NX819_18550	COG1256	bacterial-type flagellum assembly
NX819_18550	COG4786	Flagellar basal body rod
NX819_18555	COG3418	PFAM FlgN family protein
NX819_18560	COG2747	anti-sigma28 factor FlgM
NX819_18570	COG1040	competence protein
NX819_18580	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NX819_18585	COG1307	EDD domain protein, DegV family
NX819_18590	COG2197	response regulator
NX819_18595	COG4585	Histidine kinase
NX819_18600	COG1739	Uncharacterized protein family UPF0029
NX819_18605	COG1316	TRANSCRIPTIONal
NX819_18610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NX819_18615	COG0438	transferase activity, transferring glycosyl groups
NX819_18620	COG1215	transferase activity, transferring glycosyl groups
NX819_18625	COG3206	protein involved in exopolysaccharide biosynthesis
NX819_18630	COG3307	-O-antigen
NX819_18635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NX819_18640	COG0297	glycogen (starch) synthase activity
NX819_18640	COG0438	transferase activity, transferring glycosyl groups
NX819_18645	COG2244	polysaccharide biosynthetic process
NX819_18655	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX819_18655	COG2247	cell wall binding repeat
NX819_18660	COG2385	sporulation resulting in formation of a cellular spore
NX819_18660	COG2247	cell wall binding repeat
NX819_18670	COG1316	TRANSCRIPTIONal
NX819_18675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NX819_18680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NX819_18690	COG1215	transferase activity, transferring glycosyl groups
NX819_18690	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NX819_18695	COG0463	Glycosyl transferase, family 2
NX819_18715	COG1134	teichoic acid transport
NX819_18720	COG1682	transport, permease protein
NX819_18725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NX819_18730	COG0438	transferase activity, transferring glycosyl groups
NX819_18735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NX819_18740	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NX819_18745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NX819_18755	COG4193	domain, Protein
NX819_18760	COG1482	cell wall glycoprotein biosynthetic process
NX819_18765	COG0697	spore germination
NX819_18770	COG0814	amino acid
NX819_18780	COG2814	Major facilitator Superfamily
NX819_18785	COG1316	TRANSCRIPTIONal
NX819_18790	COG0561	phosphatase activity
NX819_18795	COG0791	NLP P60 protein
NX819_18805	COG2843	Capsule synthesis protein
NX819_18815	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NX819_18820	COG1609	Transcriptional regulator
NX819_18825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX819_18830	COG1869	D-ribose catabolic process
NX819_18835	COG1129	ABC transporter
NX819_18840	COG1172	Belongs to the binding-protein-dependent transport system permease family
NX819_18845	COG1879	ABC-type sugar transport system periplasmic component
NX819_18850	COG3103	Sh3 type 3 domain protein
NX819_18860	COG2249	NAD(P)H dehydrogenase (quinone) activity
NX819_18865	COG3527	Alpha-acetolactate decarboxylase
NX819_18870	COG0028	Belongs to the TPP enzyme family
NX819_18875	COG0583	DNA-binding transcription factor activity
NX819_18880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NX819_18895	COG5337	Spore coat protein CotH
NX819_18905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NX819_18915	COG0405	Gamma-glutamyltransferase
NX819_18920	COG1522	sequence-specific DNA binding
NX819_18925	COG2059	Chromate
NX819_18930	COG2059	Chromate
NX819_18940	COG0655	NAD(P)H dehydrogenase (quinone) activity
NX819_18945	COG0583	DNA-binding transcription factor activity
NX819_18995	COG3878	Protein conserved in bacteria
NX819_19000	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NX819_19005	COG4464	protein tyrosine phosphatase activity
NX819_19010	COG0489	protein tyrosine kinase activity
NX819_19015	COG3944	biosynthesis protein
NX819_19025	COG4715	Zinc finger, swim domain protein
NX819_19030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NX819_19035	COG0561	phosphatase activity
NX819_19040	COG1349	DNA-binding transcription factor activity
NX819_19045	COG0629	single-stranded DNA binding
NX819_19070	COG2972	Histidine kinase
NX819_19070	COG0745	RESPONSE REGULATOR receiver
NX819_19075	COG1970	mechanosensitive ion channel activity
NX819_19080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NX819_19085	COG0457	Tetratricopeptide repeat
NX819_19090	COG4786	Flagellar basal body rod
NX819_19095	COG4786	Flagellar basal body rod
NX819_19100	COG1077	Cell shape determining protein MreB Mrl
NX819_19105	COG1609	Transcriptional regulator
NX819_19115	COG1846	Transcriptional regulator
NX819_19120	COG2814	Major facilitator Superfamily
NX819_19125	COG3420	alginic acid biosynthetic process
NX819_19130	COG1953	Uracil, thiamine, allantoin
NX819_19135	COG0477	Major facilitator Superfamily
NX819_19140	COG1335	isochorismatase
NX819_19150	COG0004	ammonium transporteR
NX819_19155	COG0347	Belongs to the P(II) protein family
NX819_19160	COG0671	phosphoesterase, PA-phosphatase related
NX819_19170	COG0739	heme binding
NX819_19175	COG1247	-acetyltransferase
NX819_19195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX819_19200	COG0789	Transcriptional regulator
NX819_19210	COG2910	NAD(P)H-binding
NX819_19215	COG1959	2 iron, 2 sulfur cluster binding
NX819_19220	COG0804	urea catabolic process
NX819_19225	COG0832	Belongs to the urease beta subunit family
NX819_19230	COG0831	urea catabolic process
NX819_19245	COG3237	CsbD-like
NX819_19250	COG1994	Peptidase M50
NX819_19255	COG0457	Tetratricopeptide repeat
NX819_19260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NX819_19265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NX819_19275	COG2304	oxidoreductase activity
NX819_19285	COG2304	oxidoreductase activity
NX819_19290	COG2385	sporulation resulting in formation of a cellular spore
NX819_19295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NX819_19305	COG4836	Membrane
NX819_19315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NX819_19320	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NX819_19325	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NX819_19330	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NX819_19335	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NX819_19340	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NX819_19350	COG0356	it plays a direct role in the translocation of protons across the membrane
NX819_19360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NX819_19365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NX819_19370	COG4475	Protein of unknown function (DUF436)
NX819_19375	COG0698	ribose 5-phosphate isomerase
NX819_19380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NX819_19385	COG1971	Probably functions as a manganese efflux pump
NX819_19390	COG0009	L-threonylcarbamoyladenylate synthase
NX819_19395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NX819_19415	COG2890	protein-(glutamine-N5) methyltransferase activity
NX819_19420	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NX819_19425	COG0346	lactoylglutathione lyase activity
NX819_19430	COG0789	Transcriptional regulator
NX819_19435	COG0679	Auxin Efflux Carrier
NX819_19440	COG0281	malic enzyme
NX819_19445	COG1435	thymidine kinase activity
NX819_19455	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NX819_19465	COG1494	fructose-1,6-bisphosphatase
NX819_19470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NX819_19475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NX819_19480	COG0191	fructose-bisphosphate aldolase activity
NX819_19485	COG2204	response regulator
NX819_19490	COG4821	SIS domain
NX819_19495	COG0504	CTP synthase activity
NX819_19500	COG3343	RNA polymerase activity
NX819_19505	COG1960	acyl-CoA dehydrogenase activity
NX819_19510	COG0247	lactate metabolic process
NX819_19510	COG2181	nitrate reductase activity
NX819_19515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX819_19520	COG4294	response to UV
NX819_19535	COG1132	(ABC) transporter
NX819_19540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX819_19550	COG2181	nitrate reductase activity
NX819_19555	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NX819_19560	COG1140	nitrate reductase beta subunit
NX819_19565	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NX819_19570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NX819_19580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NX819_19585	COG2223	nitrite transmembrane transporter activity
NX819_19590	COG0018	arginyl-trna synthetase
NX819_19595	COG4506	Protein conserved in bacteria
NX819_19610	COG0535	radical SAM domain protein
NX819_19620	COG1131	(ABC) transporter
NX819_19625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NX819_19630	COG0612	Peptidase, M16
NX819_19635	COG0612	Peptidase, M16
NX819_19645	COG3391	amine dehydrogenase activity
NX819_19650	COG3391	amine dehydrogenase activity
NX819_19655	COG0457	Tetratricopeptide repeat
NX819_19670	COG0010	Belongs to the arginase family
NX819_19675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NX819_19680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NX819_19690	COG1994	Peptidase M50
NX819_19695	COG1942	4-Oxalocrotonate Tautomerase
NX819_19700	COG1846	Transcriptional regulator
NX819_19710	COG0477	Major facilitator Superfamily
NX819_19715	COG1959	2 iron, 2 sulfur cluster binding
NX819_19720	COG3465	dGTPase activity
NX819_19725	COG1078	dGTPase activity
NX819_19730	COG4844	belongs to the
NX819_19740	COG0697	spore germination
NX819_19745	COG0095	Lipoate-protein ligase
NX819_19750	COG0583	DNA-binding transcription factor activity
NX819_19755	COG0280	phosphate acetyltransferase
NX819_19760	COG3253	May function as heme-dependent peroxidase
NX819_19765	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_19770	COG0436	Aminotransferase
NX819_19775	COG2814	Major facilitator Superfamily
NX819_19780	COG0151	Belongs to the GarS family
NX819_19785	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_19790	COG1917	Cupin 2, conserved barrel domain protein
NX819_19795	COG0077	Prephenate dehydratase
NX819_19800	COG2814	Major facilitator Superfamily
NX819_19805	COG0833	amino acid
NX819_19810	COG4187	Peptidase family M20/M25/M40
NX819_19815	COG1012	belongs to the aldehyde dehydrogenase family
NX819_19820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NX819_19830	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NX819_19835	COG1091	dTDP-4-dehydrorhamnose reductase activity
NX819_19840	COG1088	dTDP-glucose 4,6-dehydratase activity
NX819_19845	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NX819_19850	COG3980	spore coat polysaccharide biosynthesis protein
NX819_19855	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NX819_19860	COG2089	acid synthase
NX819_19865	COG0456	acetyltransferase
NX819_19870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NX819_19875	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NX819_19880	COG0463	Glycosyl transferase, family 2
NX819_19890	COG2363	Small membrane protein
NX819_19895	COG2233	PERMEase
NX819_19905	COG1012	belongs to the aldehyde dehydrogenase family
NX819_19910	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NX819_19915	COG1216	Glycosyl transferase, family 2
NX819_19930	COG1695	Transcriptional regulator
NX819_19935	COG0351	phosphomethylpyrimidine kinase
NX819_19945	COG1621	beta-fructofuranosidase activity
NX819_19950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_19950	COG1263	PTS System
NX819_19955	COG2116	formate transmembrane transporter activity
NX819_19960	COG3711	transcriptional antiterminator
NX819_19970	COG1404	Belongs to the peptidase S8 family
NX819_19975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX819_19980	COG0778	Nitroreductase
NX819_19985	COG0772	Belongs to the SEDS family
NX819_19995	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NX819_20000	COG1845	cytochrome c oxidase, subunit III
NX819_20005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NX819_20010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NX819_20015	COG2261	transglycosylase associated protein
NX819_20020	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NX819_20025	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NX819_20030	COG2246	polysaccharide biosynthetic process
NX819_20035	COG1309	transcriptional regulator
NX819_20045	COG3162	membrane
NX819_20050	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX819_20055	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NX819_20060	COG2837	iron assimilation
NX819_20065	COG2822	iron ion transport
NX819_20070	COG0672	)-iron permease
NX819_20075	COG0352	thiamine-phosphate diphosphorylase activity
NX819_20080	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NX819_20085	COG0583	DNA-binding transcription factor activity
NX819_20090	COG1380	Effector of murein hydrolase LrgA
NX819_20095	COG1346	cytolysis
NX819_20100	COG2814	Major facilitator Superfamily
NX819_20105	COG4895	conserved protein (DUF2196)
NX819_20110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NX819_20115	COG0346	lactoylglutathione lyase activity
NX819_20125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NX819_20130	COG1404	Belongs to the peptidase S8 family
NX819_20135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_20135	COG1263	PTS System
NX819_20140	COG3711	transcriptional antiterminator
NX819_20145	COG1442	glycosyl transferase family 8
NX819_20150	COG5522	Integral membrane protein (intg_mem_TP0381)
NX819_20155	COG1846	Transcriptional regulator
NX819_20160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NX819_20165	COG2234	aminopeptidase activity
NX819_20180	COG2814	Major facilitator Superfamily
NX819_20185	COG2357	RelA SpoT domain protein
NX819_20190	COG1575	Belongs to the MenA family. Type 1 subfamily
NX819_20205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX819_20210	COG1696	Membrane protein involved in D-alanine export
NX819_20215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NX819_20220	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NX819_20225	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NX819_20230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX819_20235	COG1486	melibiose metabolic process
NX819_20240	COG1447	Phosphotransferase system cellobiose-specific component IIA
NX819_20245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NX819_20250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NX819_20255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX819_20255	COG3711	transcriptional antiterminator
NX819_20265	COG2094	Belongs to the DNA glycosylase MPG family
NX819_20270	COG0753	catalase activity
NX819_20275	COG2814	Major facilitator Superfamily
NX819_20280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NX819_20285	COG1131	(ABC) transporter
NX819_20305	COG1595	DNA-templated transcription, initiation
NX819_20310	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NX819_20315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NX819_20320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NX819_20325	COG4988	ABC transporter
NX819_20330	COG1294	oxidase, subunit
NX819_20335	COG1271	oxidase subunit
NX819_20340	COG3493	citrate carrier protein
NX819_20345	COG0501	Belongs to the peptidase M48B family
NX819_20355	COG0726	polysaccharide deacetylase
NX819_20360	COG3842	ATPase activity
NX819_20365	COG2508	Transcriptional regulator
NX819_20370	COG1012	belongs to the aldehyde dehydrogenase family
NX819_20375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX819_20385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NX819_20395	COG4585	Histidine kinase
NX819_20400	COG2197	response regulator
NX819_20405	COG2195	Cleaves the N-terminal amino acid of tripeptides
NX819_20420	COG4894	glucomannan catabolic process
NX819_20425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NX819_20430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NX819_20435	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_20440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NX819_20445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NX819_20450	COG2610	gluconate transmembrane transporter activity
NX819_20455	COG0500	methyltransferase
NX819_20460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NX819_20475	COG0753	catalase activity
NX819_20475	COG0693	protein deglycase activity
NX819_20480	COG2851	Citrate transporter
NX819_20485	COG2273	Hydrolase Family 16
NX819_20490	COG3711	transcriptional antiterminator
NX819_20500	COG2270	Major facilitator Superfamily
NX819_20505	COG0513	Belongs to the DEAD box helicase family
NX819_20510	COG2755	lipolytic protein G-D-S-L family
NX819_20510	COG3401	FG-GAP repeat protein
NX819_20565	COG3209	COG3209 Rhs family protein
NX819_20570	COG0697	spore germination
NX819_20575	COG0589	response to stress
NX819_20580	COG2723	6-phospho-beta-galactosidase activity
NX819_20585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_20585	COG2190	(PTS) system
NX819_20585	COG1263	PTS System
NX819_20600	COG5444	nuclease activity
NX819_20615	COG3507	Belongs to the glycosyl hydrolase 43 family
NX819_20630	COG2986	histidine ammonia-lyase
NX819_20635	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NX819_20640	COG1228	amidohydrolase
NX819_20645	COG0010	Belongs to the arginase family
NX819_20650	COG0833	amino acid
NX819_20655	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NX819_20660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NX819_20665	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NX819_20670	COG2390	Transcriptional regulator
NX819_20680	COG3192	ethanolamine utilization protein
NX819_20685	COG2079	MmgE PrpD family protein
NX819_20690	COG1473	amidohydrolase
NX819_20695	COG1126	abc transporter atp-binding protein
NX819_20700	COG0765	amino acid transport
NX819_20705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX819_20710	COG0456	acetyltransferase
NX819_20715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX819_20725	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NX819_20730	COG0561	phosphatase activity
NX819_20760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX819_20765	COG5294	Protein conserved in bacteria
NX819_20770	COG0577	efflux transmembrane transporter activity
NX819_20775	COG1136	(ABC) transporter
NX819_20780	COG2205	protein histidine kinase activity
NX819_20785	COG0745	RESPONSE REGULATOR receiver
NX819_20790	COG0191	fructose-bisphosphate aldolase activity
NX819_20795	COG1082	Xylose isomerase domain protein TIM barrel
NX819_20800	COG1082	Xylose isomerase domain protein TIM barrel
NX819_20805	COG0673	inositol 2-dehydrogenase activity
NX819_20810	COG2814	Major facilitator Superfamily
NX819_20815	COG1082	Xylose isomerase domain protein TIM barrel
NX819_20820	COG3962	Belongs to the TPP enzyme family
NX819_20825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX819_20830	COG3718	enzyme involved in inositol metabolism
NX819_20835	COG1012	belongs to the aldehyde dehydrogenase family
NX819_20840	COG1349	DNA-binding transcription factor activity
NX819_20845	COG0667	Aldo Keto reductase
NX819_20860	COG2814	Major facilitator Superfamily
NX819_20865	COG0326	Molecular chaperone. Has ATPase activity
NX819_20875	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_20880	COG1309	transcriptional regulator
NX819_20885	COG1012	belongs to the aldehyde dehydrogenase family
NX819_20895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX819_20905	COG1714	RDD family
NX819_20910	COG2311	Membrane
NX819_20915	COG1917	Cupin 2, conserved barrel domain protein
NX819_20920	COG1309	transcriptional regulator
NX819_20925	COG1028	Short-chain dehydrogenase reductase Sdr
NX819_20930	COG1846	Transcriptional regulator
NX819_20935	COG1380	Effector of murein hydrolase LrgA
NX819_20940	COG1346	cytolysis
NX819_20945	COG5039	Polysaccharide pyruvyl transferase
NX819_20950	COG1929	Belongs to the glycerate kinase type-1 family
NX819_20955	COG1802	Transcriptional regulator
NX819_20960	COG1070	Carbohydrate kinase
NX819_20965	COG2610	gluconate transmembrane transporter activity
NX819_20970	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NX819_20975	COG0450	alkyl hydroperoxide reductase
NX819_20980	COG3634	alkyl hydroperoxide reductase activity
NX819_20985	COG2723	6-phospho-beta-galactosidase activity
NX819_20995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX819_20995	COG2190	(PTS) system
NX819_20995	COG1263	PTS System
NX819_21000	COG2188	Transcriptional regulator
NX819_21015	COG1131	(ABC) transporter
NX819_21020	COG1994	Peptidase M50
NX819_21025	COG0535	radical SAM domain protein
NX819_21035	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NX819_21045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NX819_21060	COG1063	alcohol dehydrogenase
NX819_21080	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NX819_21085	COG0456	acetyltransferase
NX819_21090	COG0457	Tetratricopeptide repeat
NX819_21100	COG0010	Belongs to the arginase family
NX819_21105	COG0833	amino acid
NX819_21110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NX819_21115	COG3829	transcription factor binding
NX819_21120	COG5002	protein histidine kinase activity
NX819_21125	COG0745	RESPONSE REGULATOR receiver
NX819_21145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX819_21150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NX819_21155	COG4853	Protein conserved in bacteria
NX819_21160	COG4863	YycH protein
NX819_21165	COG5002	protein histidine kinase activity
NX819_21170	COG0745	RESPONSE REGULATOR receiver
NX819_21200	COG0346	lactoylglutathione lyase activity
NX819_21205	COG0305	Participates in initiation and elongation during chromosome replication
NX819_21225	COG2807	transmembrane transport
NX819_21230	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NX819_21235	COG0359	binds to the 23S rRNA
NX819_21240	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NX819_21245	COG4241	membrane
NX819_21255	COG5577	PFAM Coat F domain
NX819_21260	COG1733	regulation of RNA biosynthetic process
NX819_21265	COG1227	inorganic diphosphatase activity
NX819_21275	COG2271	Major facilitator Superfamily
NX819_21280	COG0789	Transcriptional regulator
NX819_21280	COG4978	Transcriptional regulator
NX819_21290	COG4319	ketosteroid isomerase
NX819_21295	COG1357	PFAM Pentapeptide repeats (8 copies)
NX819_21300	COG2814	Major facilitator Superfamily
NX819_21305	COG0583	DNA-binding transcription factor activity
NX819_21310	COG2153	protein acetylation
NX819_21325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX819_21330	COG1846	Transcriptional regulator
NX819_21335	COG2153	protein acetylation
NX819_21340	COG2364	Membrane
NX819_21345	COG0456	acetyltransferase
NX819_21350	COG2315	Protein conserved in bacteria
NX819_21355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NX819_21365	COG2814	Major facilitator Superfamily
NX819_21385	COG0789	Transcriptional regulator
NX819_21390	COG0697	spore germination
NX819_21400	COG1280	lysine exporter protein (LysE YggA)
NX819_21405	COG1331	Highly conserved protein containing a thioredoxin domain
NX819_21410	COG1331	Highly conserved protein containing a thioredoxin domain
NX819_21415	COG1266	CAAX protease self-immunity
NX819_21420	COG0477	Major facilitator Superfamily
NX819_21420	COG2814	Major facilitator Superfamily
NX819_21425	COG0110	maltose O-acetyltransferase activity
NX819_21430	COG0346	lactoylglutathione lyase activity
NX819_21435	COG1609	Transcriptional regulator
NX819_21440	COG0708	Exodeoxyribonuclease III
NX819_21445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NX819_21450	COG0629	single-stranded DNA binding
NX819_21455	COG0360	Binds together with S18 to 16S ribosomal RNA
NX819_21460	COG0012	GTP binding
NX819_21465	COG0243	molybdopterin cofactor binding
NX819_21470	COG4481	Protein conserved in bacteria
NX819_21475	COG3949	Membrane
NX819_21485	COG1475	DNA binding
NX819_21490	COG1192	Involved in chromosome partitioning
NX819_21500	COG1475	DNA binding
NX819_21505	COG0357	Ribosomal RNA small subunit methyltransferase G
NX819_21510	COG0445	tRNA wobble uridine modification
NX819_21515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NX819_21520	COG1847	R3H domain protein
NX819_21525	COG0706	membrane insertase activity
NX819_21530	COG0594	ribonuclease P activity