locus-tag	class	description
N7985_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N7985_00010	COG0592	DNA-directed DNA polymerase activity
N7985_00015	COG2501	S4 domain
N7985_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N7985_00030	COG0187	DNA topoisomerase II activity
N7985_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7985_00070	COG0516	GMP reductase activity
N7985_00070	COG0517	IMP dehydrogenase activity
N7985_00075	COG1686	Belongs to the peptidase S11 family
N7985_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
N7985_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
N7985_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N7985_00100	COG1428	Deoxynucleoside kinase
N7985_00105	COG1428	Deoxynucleoside kinase
N7985_00110	COG1388	LysM domain
N7985_00110	COG3858	chitin binding
N7985_00115	COG1335	isochorismatase
N7985_00120	COG0590	tRNA wobble adenosine to inosine editing
N7985_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N7985_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N7985_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N7985_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
N7985_00190	COG3853	Toxic anion resistance protein (TelA)
N7985_00195	COG1982	Orn Lys Arg decarboxylase major
N7985_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N7985_00205	COG3870	Protein conserved in bacteria
N7985_00210	COG1728	Protein conserved in bacteria
N7985_00215	COG0470	DNA polymerase III
N7985_00220	COG1774	PSP1 C-terminal conserved region
N7985_00225	COG4467	Involved in initiation control of chromosome replication
N7985_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N7985_00235	COG2827	Endonuclease containing a URI domain
N7985_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N7985_00245	COG2002	toxin-antitoxin pair type II binding
N7985_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7985_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7985_00255	COG0084	hydrolase, TatD family'
N7985_00260	COG3583	domain protein
N7985_00260	COG3584	3D domain protein
N7985_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N7985_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N7985_00280	COG4466	Protein conserved in bacteria
N7985_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N7985_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7985_00300	COG0251	oxidation-reduction process
N7985_00305	COG2088	sporulation resulting in formation of a cellular spore
N7985_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N7985_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N7985_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N7985_00325	COG0193	aminoacyl-tRNA hydrolase activity
N7985_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N7985_00340	COG2002	toxin-antitoxin pair type II binding
N7985_00345	COG2244	polysaccharide biosynthetic process
N7985_00350	COG3956	TIGRFAM MazG family protein
N7985_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N7985_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N7985_00375	COG1098	S1 RNA binding domain
N7985_00390	COG2208	phosphoserine phosphatase activity
N7985_00395	COG2304	oxidoreductase activity
N7985_00400	COG0515	serine threonine protein kinase
N7985_00405	COG0037	tRNA processing
N7985_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
N7985_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N7985_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
N7985_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N7985_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N7985_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7985_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N7985_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
N7985_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7985_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N7985_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N7985_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N7985_00470	COG1396	sequence-specific DNA binding
N7985_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N7985_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N7985_00560	COG4463	regulation of RNA biosynthetic process
N7985_00565	COG3880	PFAM UvrB UvrC protein
N7985_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
N7985_00575	COG0542	response to heat
N7985_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N7985_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
N7985_00590	COG4956	integral membrane protein (PIN domain superfamily)
N7985_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N7985_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N7985_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7985_00610	COG1045	serine acetyltransferase
N7985_00615	COG0215	cysteine-tRNA ligase activity
N7985_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
N7985_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7985_00630	COG3688	RNA-binding protein containing a PIN domain
N7985_00635	COG1595	DNA-templated transcription, initiation
N7985_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N7985_00650	COG0250	Participates in transcription elongation, termination and antitermination
N7985_00660	COG0081	regulation of translation
N7985_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N7985_00675	COG2813	Specifically methylates the guanine in position
N7985_00680	COG0085	RNA polymerase activity
N7985_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N7985_00690	COG1358	cellular component organization or biogenesis
N7985_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N7985_00700	COG0049	tRNA binding
N7985_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N7985_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N7985_00715	COG0596	Alpha beta hydrolase
N7985_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N7985_00730	COG0088	Forms part of the polypeptide exit tunnel
N7985_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N7985_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N7985_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N7985_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N7985_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N7985_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N7985_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N7985_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N7985_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N7985_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N7985_00820	COG0200	Binds to the 23S rRNA
N7985_00825	COG0201	protein transport
N7985_00830	COG0563	adenylate kinase activity
N7985_00835	COG0024	Methionine aminopeptidase
N7985_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
N7985_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N7985_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N7985_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N7985_00865	COG0202	RNA polymerase activity
N7985_00870	COG0203	ribosomal protein L17
N7985_00875	COG1122	ATPase activity
N7985_00880	COG1122	ATPase activity
N7985_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N7985_00890	COG0101	tRNA pseudouridine synthase activity
N7985_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N7985_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N7985_00905	COG2226	methyltransferase
N7985_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7985_00920	COG0489	protein tyrosine kinase activity
N7985_00930	COG2194	sulfuric ester hydrolase activity
N7985_00935	COG0726	polysaccharide deacetylase
N7985_01020	COG0659	secondary active sulfate transmembrane transporter activity
N7985_01025	COG0385	Bile acid
N7985_01030	COG2819	hydrolase of the alpha beta superfamily
N7985_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7985_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7985_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7985_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7985_01050	COG2207	Transcriptional regulator
N7985_01055	COG3876	Protein conserved in bacteria
N7985_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
N7985_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7985_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_01070	COG1263	PTS System
N7985_01075	COG1737	Transcriptional regulator
N7985_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N7985_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7985_01090	COG1683	Conserved Protein
N7985_01120	COG1595	DNA-templated transcription, initiation
N7985_01125	COG5662	AntiSigma factor
N7985_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N7985_01135	COG4856	YbbR-like protein
N7985_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7985_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N7985_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N7985_01160	COG2169	Transcriptional regulator
N7985_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7985_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N7985_01175	COG3002	Belongs to the UPF0753 family
N7985_01180	COG0288	reversible hydration of carbon dioxide
N7985_01190	COG5609	conserved protein (DUF2294)
N7985_01195	COG0640	Transcriptional regulator
N7985_01200	COG2814	Major facilitator Superfamily
N7985_01215	COG0515	serine threonine protein kinase
N7985_01230	COG1113	amino acid transport
N7985_01245	COG2602	Beta-lactamase
N7985_01250	COG2124	cytochrome p450
N7985_01260	COG0531	amino acid
N7985_01265	COG0584	glycerophosphoryl diester phosphodiesterase
N7985_01270	COG2271	Major facilitator Superfamily
N7985_01280	COG0456	acetyltransferase
N7985_01280	COG1846	Transcriptional regulator
N7985_01285	COG2271	Major facilitator Superfamily
N7985_01295	COG3409	Peptidoglycan-binding domain 1 protein
N7985_01300	COG0697	spore germination
N7985_01305	COG1917	Cupin 2, conserved barrel domain protein
N7985_01305	COG2207	Transcriptional regulator
N7985_01310	COG1397	ADP-ribosylglycohydrolase
N7985_01315	COG5444	nuclease activity
N7985_01320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
N7985_01325	COG3591	Belongs to the peptidase S1B family
N7985_01335	COG0596	Alpha beta hydrolase
N7985_01340	COG1183	phosphatidylcholine synthase activity
N7985_01345	COG0586	Pfam SNARE associated Golgi protein
N7985_01350	COG0688	phosphatidylethanolamine metabolic process
N7985_01360	COG2312	Erythromycin esterase
N7985_01365	COG1054	Belongs to the UPF0176 family
N7985_01370	COG1301	dicarboxylic acid transport
N7985_01375	COG1263	PTS System
N7985_01375	COG2190	(PTS) system
N7985_01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_01380	COG0363	glucosamine-6-phosphate deaminase activity
N7985_01385	COG2188	Transcriptional regulator
N7985_01395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7985_01400	COG0833	amino acid
N7985_01405	COG2040	homocysteine
N7985_01410	COG1115	amino acid carrier protein
N7985_01415	COG2066	Belongs to the glutaminase family
N7985_01420	COG4191	Histidine kinase
N7985_01425	COG0784	Response regulator, receiver
N7985_01430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7985_01435	COG1012	belongs to the aldehyde dehydrogenase family
N7985_01440	COG2271	Major facilitator Superfamily
N7985_01445	COG4948	Mandelate Racemase Muconate Lactonizing
N7985_01450	COG2186	Transcriptional regulator
N7985_01455	COG2721	sulfolactate sulfo-lyase activity
N7985_01460	COG3173	Aminoglycoside phosphotransferase
N7985_01470	COG0697	spore germination
N7985_01475	COG0745	RESPONSE REGULATOR receiver
N7985_01480	COG2205	protein histidine kinase activity
N7985_01485	COG1131	(ABC) transporter
N7985_01505	COG3773	Cell wall hydrolase
N7985_01510	COG2304	oxidoreductase activity
N7985_01520	COG3540	Alkaline phosphatase
N7985_01525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7985_01530	COG0805	protein transport
N7985_01535	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
N7985_01540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N7985_01545	COG0477	Major facilitator Superfamily
N7985_01550	COG1309	transcriptional regulator
N7985_01555	COG0252	asparaginase activity
N7985_01560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N7985_01565	COG1714	RDD family
N7985_01570	COG3012	SEC-C Motif Domain Protein
N7985_01570	COG1405	negative regulation of cell septum assembly
N7985_01575	COG3290	protein histidine kinase activity
N7985_01580	COG3279	Response regulator of the LytR AlgR family
N7985_01585	COG4555	ABC transporter
N7985_01590	COG1668	transmembrane transport
N7985_01595	COG0667	Aldo Keto reductase
N7985_01610	COG1595	DNA-templated transcription, initiation
N7985_01615	COG1595	DNA-templated transcription, initiation
N7985_01620	COG1876	peptidase activity
N7985_01625	COG0457	Tetratricopeptide repeat
N7985_01630	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_01635	COG0366	Alpha amylase catalytic
N7985_01640	COG0803	Belongs to the bacterial solute-binding protein 9 family
N7985_01645	COG1121	(ABC) transporter
N7985_01650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7985_01655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7985_01660	COG2310	stress, protein
N7985_01665	COG2310	stress, protein
N7985_01670	COG2310	stress, protein
N7985_01675	COG0861	Integral membrane protein TerC family
N7985_01685	COG3853	Toxic anion resistance protein (TelA)
N7985_01690	COG0477	Major facilitator Superfamily
N7985_01695	COG2814	Major facilitator Superfamily
N7985_01700	COG0640	Transcriptional regulator
N7985_01705	COG4175	Glycine betaine
N7985_01705	COG0517	IMP dehydrogenase activity
N7985_01710	COG4176	ABC-type proline glycine betaine transport system permease component
N7985_01715	COG2113	Glycine betaine
N7985_01720	COG1473	amidohydrolase
N7985_01725	COG1288	antiporter activity
N7985_01735	COG0366	Alpha amylase catalytic
N7985_01740	COG0039	L-malate dehydrogenase activity
N7985_01745	COG1620	l-lactate permease
N7985_01750	COG2814	Major facilitator Superfamily
N7985_01755	COG1846	Transcriptional regulator
N7985_01760	COG1280	lysine exporter protein (LysE YggA)
N7985_01765	COG3403	YqcI/YcgG family
N7985_01770	COG1113	amino acid transport
N7985_01775	COG3665	Urea carboxylase-associated protein
N7985_01780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N7985_01785	COG1660	Displays ATPase and GTPase activities
N7985_01790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N7985_01795	COG2226	methyltransferase
N7985_01800	COG0583	DNA-binding transcription factor activity
N7985_01805	COG3458	cephalosporin-C deacetylase activity
N7985_01810	COG3541	Predicted nucleotidyltransferase
N7985_01815	COG0506	proline dehydrogenase activity
N7985_01820	COG1012	belongs to the aldehyde dehydrogenase family
N7985_01825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7985_01830	COG2508	Transcriptional regulator
N7985_01835	COG3689	TIGRFAM TIGR03943 family protein
N7985_01840	COG0701	Predicted permease
N7985_01845	COG2267	carboxylic ester hydrolase activity
N7985_01850	COG0492	ferredoxin-NADP+ reductase activity
N7985_01855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N7985_01855	COG1587	Uroporphyrinogen-III synthase
N7985_01860	COG2146	nitrite reductase [NAD(P)H] activity
N7985_01865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7985_01870	COG0243	molybdopterin cofactor binding
N7985_01875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7985_01880	COG2223	nitrite transmembrane transporter activity
N7985_01885	COG1469	GTP cyclohydrolase I activity
N7985_01890	COG1376	ErfK ybiS ycfS ynhG family protein
N7985_01900	COG0523	cobalamin synthesis protein
N7985_01905	COG0765	amino acid transport
N7985_01910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7985_01920	COG1714	RDD family
N7985_01930	COG2723	6-phospho-beta-galactosidase activity
N7985_01940	COG3209	COG3209 Rhs family protein
N7985_01945	COG0840	transmembrane signaling receptor activity
N7985_01945	COG3290	protein histidine kinase activity
N7985_01950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N7985_01955	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
N7985_01960	COG1733	regulation of RNA biosynthetic process
N7985_01965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_01995	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N7985_02000	COG2814	Major facilitator Superfamily
N7985_02010	COG0697	spore germination
N7985_02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7985_02025	COG2364	Membrane
N7985_02030	COG1126	abc transporter atp-binding protein
N7985_02035	COG0765	amino acid transport
N7985_02040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7985_02045	COG0583	DNA-binding transcription factor activity
N7985_02050	COG0163	prenyltransferase activity
N7985_02055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N7985_02070	COG0596	Alpha beta hydrolase
N7985_02075	COG3104	oligopeptide transport
N7985_02080	COG5434	Belongs to the glycosyl hydrolase 28 family
N7985_02090	COG0697	spore germination
N7985_02100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N7985_02105	COG1136	(ABC) transporter
N7985_02110	COG0577	efflux transmembrane transporter activity
N7985_02115	COG0745	RESPONSE REGULATOR receiver
N7985_02120	COG3850	Histidine kinase
N7985_02120	COG5002	protein histidine kinase activity
N7985_02125	COG0457	Tetratricopeptide repeat
N7985_02145	COG0527	aspartate kinase activity
N7985_02150	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7985_02155	COG4605	iron ion homeostasis
N7985_02160	COG4604	ABC transporter, ATP-binding protein
N7985_02165	COG4607	ABC-type enterochelin transport system periplasmic component
N7985_02170	COG2814	Major facilitator Superfamily
N7985_02175	COG1309	transcriptional regulator
N7985_02180	COG0778	Nitroreductase
N7985_02185	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N7985_02190	COG0640	Transcriptional regulator
N7985_02195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7985_02200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7985_02205	COG1012	belongs to the aldehyde dehydrogenase family
N7985_02210	COG4975	Glucose uptake
N7985_02215	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_02220	COG4549	nuclear export factor GLE1
N7985_02225	COG2372	response to copper ion
N7985_02225	COG1276	copper resistance
N7985_02230	COG1349	DNA-binding transcription factor activity
N7985_02240	COG2213	PTS system mannitol-specific
N7985_02245	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7985_02250	COG0246	Mannitol dehydrogenase
N7985_02255	COG0473	3-isopropylmalate dehydrogenase activity
N7985_02260	COG0681	Belongs to the peptidase S26 family
N7985_02265	COG0412	Dienelactone hydrolase
N7985_02270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N7985_02280	COG0561	phosphatase activity
N7985_02285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
N7985_02290	COG1914	H( )-stimulated, divalent metal cation uptake system
N7985_02295	COG4336	lyase activity
N7985_02300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
N7985_02305	COG1984	allophanate hydrolase subunit 2
N7985_02310	COG1414	Transcriptional regulator
N7985_02315	COG2755	lipolytic protein G-D-S-L family
N7985_02325	COG2329	Antibiotic biosynthesis monooxygenase
N7985_02330	COG0768	penicillin binding
N7985_02335	COG4989	oxidoreductase activity
N7985_02340	COG3711	transcriptional antiterminator
N7985_02345	COG0318	PFAM AMP-dependent synthetase and ligase
N7985_02350	COG2226	methyltransferase
N7985_02355	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_02360	COG1917	Cupin 2, conserved barrel domain protein
N7985_02365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7985_02370	COG3871	stress protein (general stress protein 26)
N7985_02380	COG2814	Major facilitator Superfamily
N7985_02385	COG1522	sequence-specific DNA binding
N7985_02390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N7985_02390	COG0551	DNA topoisomerase type I activity
N7985_02395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
N7985_02400	COG3706	GGDEF domain
N7985_02405	COG5298	Protein conserved in bacteria
N7985_02410	COG1215	transferase activity, transferring glycosyl groups
N7985_02420	COG0531	amino acid
N7985_02425	COG0494	nUDIX hydrolase
N7985_02430	COG0028	Belongs to the TPP enzyme family
N7985_02445	COG1914	H( )-stimulated, divalent metal cation uptake system
N7985_02450	COG2261	transglycosylase associated protein
N7985_02455	COG4876	unkown
N7985_02460	COG2217	Heavy metal translocating P-type atpase
N7985_02465	COG3729	General stress protein
N7985_02470	COG0662	Cupin 2, conserved barrel domain protein
N7985_02475	COG2329	Antibiotic biosynthesis monooxygenase
N7985_02480	COG3546	catalase activity
N7985_02485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N7985_02490	COG3290	protein histidine kinase activity
N7985_02495	COG4565	transcriptional regulatory protein
N7985_02500	COG1301	dicarboxylic acid transport
N7985_02505	COG0628	permease
N7985_02510	COG1131	(ABC) transporter
N7985_02515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N7985_02525	COG1960	acyl-CoA dehydrogenase activity
N7985_02540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N7985_02545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7985_02550	COG1181	Belongs to the D-alanine--D-alanine ligase family
N7985_02555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N7985_02560	COG0513	Belongs to the DEAD box helicase family
N7985_02565	COG3402	PFAM membrane-flanked domain
N7985_02570	COG3428	Bacterial PH domain
N7985_02575	COG0705	Rhomboid family
N7985_02580	COG0736	holo-[acyl-carrier-protein] synthase activity
N7985_02585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N7985_02590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N7985_02595	COG0864	Transcriptional regulator
N7985_02600	COG2337	Toxic component of a toxin-antitoxin (TA) module
N7985_02605	COG1366	Belongs to the anti-sigma-factor antagonist family
N7985_02610	COG1366	Belongs to the anti-sigma-factor antagonist family
N7985_02615	COG2172	sigma factor antagonist activity
N7985_02620	COG2208	phosphoserine phosphatase activity
N7985_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
N7985_02630	COG2172	sigma factor antagonist activity
N7985_02635	COG1191	sigma factor activity
N7985_02640	COG2208	phosphoserine phosphatase activity
N7985_02645	COG2183	response to ionizing radiation
N7985_02655	COG3091	SprT-like family
N7985_02695	COG0582	viral genome integration into host DNA
N7985_02700	COG2856	Zn peptidase
N7985_02705	COG1396	sequence-specific DNA binding
N7985_02735	COG1674	ftsk spoiiie
N7985_02740	COG2946	Replication initiation factor
N7985_02775	COG0433	COG0433 Predicted ATPase
N7985_02785	COG5644	endopeptidase inhibitor activity
N7985_02790	COG0791	NLP P60 protein
N7985_02790	COG0741	lytic transglycosylase activity
N7985_02810	COG0457	Tetratricopeptide repeat
N7985_02825	COG0582	viral genome integration into host DNA
N7985_02840	COG0457	Tetratricopeptide repeat
N7985_02870	COG5444	nuclease activity
N7985_02880	COG1476	TRANSCRIPTIONal
N7985_02890	COG3239	Fatty acid desaturase
N7985_02895	COG1278	Cold shock
N7985_02900	COG1329	Transcriptional regulator
N7985_02905	COG0697	spore germination
N7985_02910	COG1917	Cupin 2, conserved barrel domain protein
N7985_02910	COG2207	Transcriptional regulator
N7985_02915	COG0697	spore germination
N7985_02920	COG3708	Transcriptional regulator
N7985_02920	COG2207	Transcriptional regulator
N7985_02925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7985_02930	COG0477	Major facilitator Superfamily
N7985_02940	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
N7985_02955	COG1309	transcriptional regulator
N7985_02960	COG0697	spore germination
N7985_02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7985_02970	COG2030	dehydratase
N7985_02975	COG3545	Serine hydrolase
N7985_02980	COG1733	regulation of RNA biosynthetic process
N7985_02985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7985_02990	COG1733	regulation of RNA biosynthetic process
N7985_02995	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7985_03000	COG2814	Major facilitator Superfamily
N7985_03005	COG1309	transcriptional regulator
N7985_03010	COG0640	Transcriptional regulator
N7985_03015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N7985_03025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7985_03030	COG0697	spore germination
N7985_03035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7985_03040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7985_03045	COG0640	Transcriptional regulator
N7985_03050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7985_03065	COG4585	Histidine kinase
N7985_03070	COG2197	response regulator
N7985_03075	COG2409	Drug exporters of the RND superfamily
N7985_03080	COG0596	Alpha beta hydrolase
N7985_03085	COG1811	Na channel or pump
N7985_03090	COG0789	Transcriptional regulator
N7985_03090	COG4978	Transcriptional regulator
N7985_03095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N7985_03100	COG0778	Nitroreductase
N7985_03105	COG0346	lactoylglutathione lyase activity
N7985_03110	COG2259	Doxx family
N7985_03115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7985_03135	COG2323	membrane
N7985_03140	COG2323	membrane
N7985_03145	COG0071	Belongs to the small heat shock protein (HSP20) family
N7985_03160	COG1309	transcriptional regulator
N7985_03170	COG0456	acetyltransferase
N7985_03175	COG0488	(ABC) transporter
N7985_03180	COG1113	amino acid transport
N7985_03185	COG2318	DinB family
N7985_03190	COG1846	Transcriptional regulator
N7985_03195	COG1033	growth of symbiont in host cell
N7985_03195	COG2409	Drug exporters of the RND superfamily
N7985_03200	COG0778	Nitroreductase
N7985_03205	COG1846	Transcriptional regulator
N7985_03210	COG2814	Major facilitator Superfamily
N7985_03215	COG0730	response to heat
N7985_03220	COG1802	Transcriptional regulator
N7985_03225	COG1388	LysM domain
N7985_03225	COG3858	chitin binding
N7985_03230	COG1819	glycosyl
N7985_03240	COG1785	Belongs to the alkaline phosphatase family
N7985_03245	COG5646	InterPro IPR014922
N7985_03255	COG0454	-acetyltransferase
N7985_03260	COG1078	dGTPase activity
N7985_03265	COG1388	LysM domain
N7985_03270	COG2814	Major facilitator Superfamily
N7985_03275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7985_03280	COG1447	Phosphotransferase system cellobiose-specific component IIA
N7985_03285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7985_03290	COG2723	6-phospho-beta-galactosidase activity
N7985_03295	COG2188	Transcriptional regulator
N7985_03300	COG1940	carbohydrate kinase activity
N7985_03305	COG1482	cell wall glycoprotein biosynthetic process
N7985_03310	COG4124	Belongs to the glycosyl hydrolase 26 family
N7985_03355	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N7985_03360	COG0802	atpase or kinase
N7985_03365	COG1214	PFAM Peptidase M22, glycoprotease
N7985_03370	COG0456	acetyltransferase
N7985_03375	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N7985_03380	COG0488	(ABC) transporter
N7985_03385	COG0315	cyclic pyranopterin monophosphate synthase activity
N7985_03390	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
N7985_03395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7985_03400	COG0805	protein transport
N7985_03410	COG1266	CAAX protease self-immunity
N7985_03420	COG0459	protein refolding
N7985_03425	COG1073	alpha beta
N7985_03430	COG0457	Tetratricopeptide repeat
N7985_03435	COG1063	alcohol dehydrogenase
N7985_03440	COG2211	Major facilitator Superfamily
N7985_03445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7985_03450	COG1842	Phage shock protein A
N7985_03455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N7985_03460	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
N7985_03465	COG4260	virion core protein, lumpy skin disease virus
N7985_03475	COG2814	Major facilitator Superfamily
N7985_03480	COG1063	alcohol dehydrogenase
N7985_03485	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N7985_03490	COG0823	Involved in the tonB-independent uptake of proteins
N7985_03505	COG2267	carboxylic ester hydrolase activity
N7985_03515	COG2132	Multicopper oxidase
N7985_03520	COG1113	amino acid transport
N7985_03530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N7985_03535	COG0714	Associated with various cellular activities
N7985_03540	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
N7985_03545	COG1305	Transglutaminase-like
N7985_03550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N7985_03550	COG0519	Catalyzes the synthesis of GMP from XMP
N7985_03565	COG2252	PERMEase
N7985_03570	COG3064	Membrane
N7985_03580	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
N7985_03590	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N7985_03595	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N7985_03600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N7985_03605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N7985_03610	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7985_03615	COG0047	phosphoribosylformylglycinamidine synthase activity
N7985_03620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7985_03625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N7985_03630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N7985_03635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N7985_03640	COG0138	bifunctional purine biosynthesis protein purh
N7985_03645	COG0151	Belongs to the GarS family
N7985_03650	COG1522	sequence-specific DNA binding
N7985_03655	COG0531	amino acid
N7985_03665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7985_03670	COG1470	cell adhesion involved in biofilm formation
N7985_03675	COG4496	protein, YerC YecD
N7985_03680	COG0069	glutamate synthase activity
N7985_03685	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
N7985_03690	COG0210	DNA helicase
N7985_03695	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N7985_03700	COG4851	CamS sex pheromone cAM373 precursor
N7985_03705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7985_03710	COG1285	pathogenesis
N7985_03715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7985_03720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7985_03725	COG0154	amidase activity
N7985_03730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7985_03740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7985_03745	COG1597	lipid kinase activity
N7985_03750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N7985_03765	COG5444	nuclease activity
N7985_03770	COG3391	amine dehydrogenase activity
N7985_03775	COG0457	Tetratricopeptide repeat
N7985_03785	COG0217	transcriptional regulatory protein
N7985_03795	COG1309	transcriptional regulator
N7985_03800	COG3631	Ketosteroid isomerase-related protein
N7985_03820	COG3546	catalase activity
N7985_03825	COG0454	-acetyltransferase
N7985_03835	COG5578	integral membrane protein
N7985_03840	COG2972	Histidine kinase
N7985_03845	COG4753	response regulator
N7985_03845	COG2207	Transcriptional regulator
N7985_03850	COG1653	transport
N7985_03855	COG1175	transmembrane transport
N7985_03860	COG0395	ABC-type sugar transport system, permease component
N7985_03865	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N7985_03870	COG2207	Transcriptional regulator
N7985_03875	COG2755	lipolytic protein G-D-S-L family
N7985_03885	COG5578	integral membrane protein
N7985_03890	COG3401	FG-GAP repeat protein
N7985_03895	COG3401	FG-GAP repeat protein
N7985_03900	COG2755	lipolytic protein G-D-S-L family
N7985_03905	COG1874	Beta-galactosidase
N7985_03915	COG1653	transport
N7985_03920	COG4209	transmembrane transport
N7985_03925	COG0395	ABC-type sugar transport system, permease component
N7985_03930	COG1486	melibiose metabolic process
N7985_03935	COG2323	membrane
N7985_03940	COG2329	Antibiotic biosynthesis monooxygenase
N7985_03945	COG0346	lactoylglutathione lyase activity
N7985_03960	COG5583	Uncharacterized small protein (DUF2292)
N7985_03965	COG0670	Belongs to the BI1 family
N7985_03970	COG0697	spore germination
N7985_03975	COG1846	Transcriptional regulator
N7985_03980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7985_04000	COG1368	sulfuric ester hydrolase activity
N7985_04005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N7985_04010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7985_04015	COG1442	glycosyl transferase family 8
N7985_04020	COG1216	Glycosyl transferase, family 2
N7985_04025	COG1442	glycosyl transferase family 8
N7985_04030	COG2223	nitrite transmembrane transporter activity
N7985_04035	COG1011	Hydrolase
N7985_04040	COG0531	amino acid
N7985_04045	COG1012	belongs to the aldehyde dehydrogenase family
N7985_04050	COG0840	transmembrane signaling receptor activity
N7985_04055	COG0488	(ABC) transporter
N7985_04065	COG0789	Transcriptional regulator
N7985_04070	COG2814	Major facilitator Superfamily
N7985_04075	COG1404	Belongs to the peptidase S8 family
N7985_04090	COG0488	(ABC) transporter
N7985_04095	COG0513	Belongs to the DEAD box helicase family
N7985_04100	COG0456	acetyltransferase
N7985_04105	COG2130	NADP-dependent
N7985_04110	COG1120	ATPase activity
N7985_04115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7985_04120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7985_04125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
N7985_04140	COG3866	Pectate lyase
N7985_04145	COG0471	metal ion transport
N7985_04150	COG3290	protein histidine kinase activity
N7985_04155	COG4565	transcriptional regulatory protein
N7985_04160	COG3181	Tripartite tricarboxylate transporter family receptor
N7985_04170	COG2851	Citrate transporter
N7985_04175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7985_04180	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
N7985_04185	COG1254	Belongs to the acylphosphatase family
N7985_04190	COG2258	MOSC domain
N7985_04210	COG0024	Methionine aminopeptidase
N7985_04215	COG1263	PTS System
N7985_04215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_04220	COG1368	sulfuric ester hydrolase activity
N7985_04235	COG1115	amino acid carrier protein
N7985_04240	COG0531	amino acid
N7985_04255	COG0697	spore germination
N7985_04260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_04260	COG1263	PTS System
N7985_04265	COG0366	Alpha amylase catalytic
N7985_04270	COG2188	Transcriptional regulator
N7985_04275	COG0778	Nitroreductase
N7985_04280	COG0737	Belongs to the 5'-nucleotidase family
N7985_04285	COG0693	protein deglycase activity
N7985_04290	COG2814	Major facilitator Superfamily
N7985_04295	COG4840	Belongs to the UPF0435 family
N7985_04300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7985_04305	COG4980	gas vesicle protein
N7985_04310	COG1295	ribonuclease BN
N7985_04315	COG0477	Major facilitator Superfamily
N7985_04320	COG0387	Pfam Sodium calcium exchanger
N7985_04330	COG0668	transmembrane transport
N7985_04335	COG0535	radical SAM domain protein
N7985_04345	COG0726	polysaccharide deacetylase
N7985_04350	COG2084	Dehydrogenase
N7985_04355	COG0598	Magnesium transport protein CorA
N7985_04360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N7985_04365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N7985_04375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N7985_04380	COG4637	Psort location Cytoplasmic, score
N7985_04390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7985_04395	COG0022	dehydrogenase e1 component
N7985_04400	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7985_04405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7985_04410	COG3284	Transcriptional regulator
N7985_04420	COG1742	UPF0060 membrane protein
N7985_04445	COG4842	Belongs to the WXG100 family
N7985_04450	COG1486	melibiose metabolic process
N7985_04455	COG1737	Transcriptional regulator
N7985_04460	COG1263	PTS System
N7985_04460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_04465	COG5434	Belongs to the glycosyl hydrolase 28 family
N7985_04470	COG1132	(ABC) transporter
N7985_04475	COG1132	(ABC) transporter
N7985_04480	COG2259	Doxx family
N7985_04485	COG2514	catechol 2,3-dioxygenase activity
N7985_04490	COG4585	Histidine kinase
N7985_04495	COG2197	response regulator
N7985_04500	COG1131	(ABC) transporter
N7985_04505	COG0842	Transport permease protein
N7985_04505	COG1511	domain protein
N7985_04510	COG0842	Transport permease protein
N7985_04515	COG1695	Transcriptional regulator
N7985_04520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N7985_04525	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
N7985_04530	COG2318	DinB family
N7985_04535	COG2814	Major facilitator Superfamily
N7985_04540	COG1846	Transcriptional regulator
N7985_04545	COG0392	lysyltransferase activity
N7985_04545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N7985_04550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7985_04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7985_04560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7985_04565	COG0384	phenazine biosynthesis protein PhzF
N7985_04570	COG0778	Nitroreductase
N7985_04585	COG1090	epimerase
N7985_04590	COG2137	regulation of response to DNA damage stimulus
N7985_04600	COG2814	Major facilitator Superfamily
N7985_04615	COG3103	Sh3 type 3 domain protein
N7985_04620	COG5658	integral membrane protein
N7985_04625	COG0596	Alpha beta hydrolase
N7985_04630	COG0463	Glycosyl transferase, family 2
N7985_04635	COG4485	Bacterial membrane protein, YfhO
N7985_04640	COG1988	membrane-bound metal-dependent
N7985_04645	COG1194	a g-specific adenine glycosylase
N7985_04655	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_04670	COG3557	Belongs to the UPF0374 family
N7985_04675	COG1132	(ABC) transporter
N7985_04680	COG4129	membrane
N7985_04685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N7985_04690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N7985_04695	COG0735	belongs to the Fur family
N7985_04805	COG4326	sporulation control protein
N7985_04815	COG5577	PFAM Coat F domain
N7985_04825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N7985_04840	COG0753	catalase activity
N7985_04845	COG1116	anion transmembrane transporter activity
N7985_04850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7985_04855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7985_04860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7985_04870	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N7985_04880	COG1476	TRANSCRIPTIONal
N7985_04890	COG3382	B3 4 domain protein
N7985_04895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N7985_04905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N7985_04910	COG0789	Transcriptional regulator
N7985_04915	COG1664	Polymer-forming cytoskeletal
N7985_04920	COG1664	Polymer-forming cytoskeletal
N7985_04925	COG2766	serine protein kinase
N7985_04930	COG2718	Belongs to the UPF0229 family
N7985_04935	COG1846	Transcriptional regulator
N7985_04940	COG1566	PFAM secretion protein HlyD family protein
N7985_04945	COG2814	Major facilitator Superfamily
N7985_04950	COG0655	NAD(P)H dehydrogenase (quinone) activity
N7985_04970	COG1725	Transcriptional regulator
N7985_04975	COG1131	(ABC) transporter
N7985_04980	COG1131	(ABC) transporter
N7985_04985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N7985_04990	COG1278	Cold shock
N7985_04995	COG1464	Belongs to the NlpA lipoprotein family
N7985_05000	COG3706	GGDEF domain
N7985_05005	COG1823	symporter activity
N7985_05035	COG5577	PFAM Coat F domain
N7985_05040	COG1525	nuclease
N7985_05040	COG4085	toxin activity
N7985_05040	COG0737	Belongs to the 5'-nucleotidase family
N7985_05045	COG3764	Sortase (surface protein transpeptidase)
N7985_05050	COG0564	pseudouridine synthase activity
N7985_05060	COG0517	IMP dehydrogenase activity
N7985_05065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7985_05070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N7985_05070	COG3153	acetyltransferase
N7985_05075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7985_05080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
N7985_05085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N7985_05090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N7985_05095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N7985_05100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7985_05105	COG2203	Gaf domain
N7985_05105	COG4585	Histidine kinase
N7985_05110	COG2197	response regulator
N7985_05115	COG0431	NADPH-dependent FMN reductase
N7985_05130	COG1388	LysM domain
N7985_05130	COG0791	NLP P60 protein
N7985_05135	COG1959	2 iron, 2 sulfur cluster binding
N7985_05140	COG0668	transmembrane transport
N7985_05145	COG2719	SpoVR family
N7985_05150	COG1785	Belongs to the alkaline phosphatase family
N7985_05155	COG1388	LysM domain
N7985_05155	COG0791	NLP P60 protein
N7985_05160	COG0583	DNA-binding transcription factor activity
N7985_05165	COG0372	Belongs to the citrate synthase family
N7985_05170	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_05175	COG0531	amino acid
N7985_05180	COG0733	neurotransmitter:sodium symporter activity
N7985_05185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7985_05190	COG0456	acetyltransferase
N7985_05205	COG1595	DNA-templated transcription, initiation
N7985_05210	COG0667	Aldo Keto reductase
N7985_05215	COG0204	Acyl-transferase
N7985_05220	COG1253	flavin adenine dinucleotide binding
N7985_05225	COG0789	Transcriptional regulator
N7985_05230	COG0436	Aminotransferase
N7985_05235	COG1253	flavin adenine dinucleotide binding
N7985_05240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N7985_05245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N7985_05250	COG0584	glycerophosphoryl diester phosphodiesterase
N7985_05260	COG0668	transmembrane transport
N7985_05265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N7985_05270	COG0726	polysaccharide deacetylase
N7985_05275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7985_05280	COG1757	Na H antiporter
N7985_05285	COG0589	response to stress
N7985_05295	COG1132	(ABC) transporter
N7985_05300	COG1132	(ABC) transporter
N7985_05305	COG0702	epimerase
N7985_05325	COG0189	ligase activity
N7985_05330	COG0189	ligase activity
N7985_05335	COG4399	Belongs to the UPF0754 family
N7985_05340	COG3679	Belongs to the UPF0342 family
N7985_05345	COG4335	DNA alkylation repair
N7985_05350	COG0561	phosphatase activity
N7985_05355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7985_05360	COG0475	glutathione-regulated potassium exporter activity
N7985_05365	COG0490	domain, Protein
N7985_05375	COG1024	Enoyl-CoA hydratase
N7985_05385	COG4152	abc transporter atp-binding protein
N7985_05390	COG1668	transmembrane transport
N7985_05395	COG0420	3'-5' exonuclease activity
N7985_05400	COG4717	serine-type aminopeptidase activity
N7985_05405	COG3481	metal-dependent phosphohydrolase, HD sub domain
N7985_05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N7985_05445	COG1846	Transcriptional regulator
N7985_05450	COG4980	gas vesicle protein
N7985_05465	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N7985_05470	COG0537	adenosine 5'-monophosphoramidase activity
N7985_05475	COG1131	(ABC) transporter
N7985_05480	COG4473	ABC transporter
N7985_05490	COG1473	amidohydrolase
N7985_05495	COG3069	C4-dicarboxylate transmembrane transporter activity
N7985_05505	COG2329	Antibiotic biosynthesis monooxygenase
N7985_05510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7985_05515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N7985_05520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N7985_05525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
N7985_05530	COG1309	transcriptional regulator
N7985_05535	COG1511	domain protein
N7985_05540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7985_05545	COG4377	Putative membrane peptidase family (DUF2324)
N7985_05555	COG1363	Peptidase, m42
N7985_05560	COG4405	Protein conserved in bacteria
N7985_05565	COG1301	dicarboxylic acid transport
N7985_05575	COG1234	tRNA 3'-trailer cleavage
N7985_05580	COG0095	Lipoate-protein ligase
N7985_05585	COG0702	epimerase
N7985_05590	COG0318	PFAM AMP-dependent synthetase and ligase
N7985_05600	COG0501	Belongs to the peptidase M48B family
N7985_05610	COG0456	acetyltransferase
N7985_05615	COG0604	alcohol dehydrogenase
N7985_05620	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
N7985_05625	COG0406	alpha-ribazole phosphatase activity
N7985_05630	COG0183	Belongs to the thiolase family
N7985_05635	COG0318	PFAM AMP-dependent synthetase and ligase
N7985_05640	COG1268	BioY protein
N7985_05645	COG0840	transmembrane signaling receptor activity
N7985_05650	COG0723	plastoquinol--plastocyanin reductase activity
N7985_05650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7985_05655	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_05665	COG4903	ComK protein
N7985_05670	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_05680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7985_05695	COG0398	Pfam SNARE associated Golgi protein
N7985_05700	COG0681	Belongs to the peptidase S26 family
N7985_05705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7985_05710	COG1846	Transcriptional regulator
N7985_05720	COG0738	Major facilitator superfamily
N7985_05725	COG0673	inositol 2-dehydrogenase activity
N7985_05730	COG0561	phosphatase activity
N7985_05735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N7985_05740	COG1609	Transcriptional regulator
N7985_05745	COG3180	Ammonia monooxygenase
N7985_05750	COG0477	Major facilitator Superfamily
N7985_05750	COG2814	Major facilitator Superfamily
N7985_05755	COG4533	DNA binding
N7985_05765	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
N7985_05770	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
N7985_05775	COG1074	ATP-dependent DNA helicase activity
N7985_05780	COG0420	3'-5' exonuclease activity
N7985_05785	COG0419	ATPase involved in DNA repair
N7985_05790	COG1403	HNH endonuclease
N7985_05830	COG5337	Spore coat protein CotH
N7985_05835	COG0179	Fumarylacetoacetate (FAA) hydrolase
N7985_05845	COG1404	Belongs to the peptidase S8 family
N7985_05855	COG0367	asparagine synthase
N7985_05860	COG2318	DinB family
N7985_05870	COG0534	Mate efflux family protein
N7985_05875	COG1917	Cupin 2, conserved barrel domain protein
N7985_05875	COG2207	Transcriptional regulator
N7985_05880	COG1609	Transcriptional regulator
N7985_05885	COG0673	inositol 2-dehydrogenase activity
N7985_05890	COG2318	DinB family
N7985_05895	COG1279	arginine transmembrane transporter activity
N7985_05900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7985_05905	COG1357	PFAM Pentapeptide repeats (8 copies)
N7985_05910	COG2267	carboxylic ester hydrolase activity
N7985_05915	COG0529	Catalyzes the synthesis of activated sulfate
N7985_05920	COG2046	Belongs to the sulfate adenylyltransferase family
N7985_05925	COG0175	sulfate reduction
N7985_05930	COG2045	Belongs to the ComB family
N7985_05935	COG1809	phosphosulfolactate synthase activity
N7985_05940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7985_05945	COG4948	Mandelate Racemase Muconate Lactonizing
N7985_05950	COG2814	Major facilitator Superfamily
N7985_05955	COG0454	-acetyltransferase
N7985_05960	COG2153	protein acetylation
N7985_05965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N7985_05965	COG0646	methionine synthase
N7985_05970	COG1666	GTP binding
N7985_05995	COG1695	Transcriptional regulator
N7985_06010	COG3227	Zinc metalloprotease (Elastase)
N7985_06015	COG1307	EDD domain protein, DegV family
N7985_06020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7985_06040	COG0561	phosphatase activity
N7985_06045	COG1073	alpha beta
N7985_06050	COG2151	metal-sulfur cluster biosynthetic enzyme
N7985_06060	COG0277	FAD linked oxidase domain protein
N7985_06065	COG2271	Major facilitator Superfamily
N7985_06070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N7985_06075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N7985_06085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N7985_06090	COG0505	Belongs to the CarA family
N7985_06095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N7985_06100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N7985_06115	COG2267	carboxylic ester hydrolase activity
N7985_06125	COG1744	ABC transporter substrate-binding protein PnrA-like
N7985_06140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7985_06145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7985_06150	COG5504	Zn-dependent protease
N7985_06155	COG0444	Belongs to the ABC transporter superfamily
N7985_06160	COG4608	Belongs to the ABC transporter superfamily
N7985_06170	COG0601	transmembrane transport
N7985_06175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7985_06185	COG0180	Tryptophanyl-tRNA synthetase
N7985_06190	COG4166	transmembrane transport
N7985_06195	COG0601	transmembrane transport
N7985_06200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7985_06205	COG0444	Belongs to the ABC transporter superfamily
N7985_06210	COG4608	Belongs to the ABC transporter superfamily
N7985_06215	COG2814	Major facilitator Superfamily
N7985_06220	COG0456	acetyltransferase
N7985_06225	COG1393	Belongs to the ArsC family
N7985_06230	COG0861	Integral membrane protein TerC family
N7985_06240	COG4862	establishment of competence for transformation
N7985_06250	COG4469	Competence protein
N7985_06255	COG1164	Oligoendopeptidase f
N7985_06265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N7985_06270	COG2346	COG2346, Truncated hemoglobins
N7985_06275	COG0741	lytic transglycosylase activity
N7985_06280	COG4116	CYTH
N7985_06290	COG2357	RelA SpoT domain protein
N7985_06295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N7985_06300	COG0564	pseudouridine synthase activity
N7985_06305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N7985_06310	COG0475	glutathione-regulated potassium exporter activity
N7985_06310	COG0569	domain protein
N7985_06315	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N7985_06320	COG0352	thiamine-phosphate diphosphorylase activity
N7985_06325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7985_06330	COG2104	thiamine diphosphate biosynthetic process
N7985_06335	COG2022	thiamine diphosphate biosynthetic process
N7985_06340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N7985_06345	COG0351	phosphomethylpyrimidine kinase
N7985_06350	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N7985_06405	COG0210	DNA helicase
N7985_06415	COG2153	protein acetylation
N7985_06420	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N7985_06425	COG2382	esterase
N7985_06430	COG0626	cystathionine gamma-synthase activity
N7985_06435	COG0626	cystathionine gamma-synthase activity
N7985_06440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7985_06445	COG5505	Protein of unknown function (DUF819)
N7985_06460	COG5444	nuclease activity
N7985_06510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N7985_06515	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_06525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7985_06525	COG3711	transcriptional antiterminator
N7985_06530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7985_06530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7985_06530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7985_06535	COG1482	cell wall glycoprotein biosynthetic process
N7985_06545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7985_06555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N7985_06570	COG0109	protoheme IX farnesyltransferase activity
N7985_06580	COG0726	polysaccharide deacetylase
N7985_06595	COG5504	Zn-dependent protease
N7985_06600	COG2205	protein histidine kinase activity
N7985_06610	COG3383	formate dehydrogenase (NAD+) activity
N7985_06615	COG2427	Protein of unknown function (DUF1641)
N7985_06625	COG1051	belongs to the nudix hydrolase family
N7985_06635	COG2124	cytochrome p450
N7985_06640	COG1819	glycosyl
N7985_06660	COG1587	Uroporphyrinogen-III synthase
N7985_06665	COG0390	transport system, permease component
N7985_06670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7985_06675	COG0697	spore germination
N7985_06680	COG4297	protein containing double-stranded beta helix domain
N7985_06690	COG1252	NADH dehydrogenase
N7985_06695	COG1904	glucuronate isomerase
N7985_06700	COG2211	Major facilitator Superfamily
N7985_06705	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N7985_06710	COG1063	alcohol dehydrogenase
N7985_06715	COG1312	Catalyzes the dehydration of D-mannonate
N7985_06720	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_06725	COG2271	Major facilitator Superfamily
N7985_06730	COG1609	Transcriptional regulator
N7985_06735	COG0246	Mannitol dehydrogenase
N7985_06740	COG2721	sulfolactate sulfo-lyase activity
N7985_06745	COG0730	response to heat
N7985_06750	COG2318	DinB family
N7985_06755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N7985_06760	COG0457	Tetratricopeptide repeat
N7985_06770	COG2350	Protein conserved in bacteria
N7985_06775	COG5632	N-Acetylmuramoyl-L-alanine amidase
N7985_06775	COG1388	LysM domain
N7985_06775	COG3409	Peptidoglycan-binding domain 1 protein
N7985_06785	COG4195	phage-related replication protein
N7985_06790	COG3546	catalase activity
N7985_06795	COG2856	Zn peptidase
N7985_06800	COG1396	sequence-specific DNA binding
N7985_06810	COG1522	sequence-specific DNA binding
N7985_06815	COG1484	DNA-dependent DNA replication
N7985_06835	COG1595	DNA-templated transcription, initiation
N7985_06840	COG5484	DNA packaging
N7985_06840	COG3728	DNA packaging
N7985_06845	COG1783	phage Terminase large subunit
N7985_06850	COG5518	Phage portal protein
N7985_06855	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N7985_06860	COG4653	Phage capsid family
N7985_06910	COG3953	SLT domain
N7985_06910	COG5412	phage tail tape measure protein
N7985_06915	COG1652	LysM domain
N7985_06920	COG4193	domain, Protein
N7985_06930	COG3628	GPW Gp25 family protein
N7985_06935	COG3299	homolog of phage Mu protein gp47
N7985_06940	COG3778	Protein conserved in bacteria
N7985_06980	COG5632	N-Acetylmuramoyl-L-alanine amidase
N7985_06980	COG3409	Peptidoglycan-binding domain 1 protein
N7985_07000	COG0306	phosphate transporter
N7985_07005	COG1392	Phosphate transport regulator
N7985_07010	COG0531	amino acid
N7985_07015	COG0346	lactoylglutathione lyase activity
N7985_07025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N7985_07030	COG0463	Glycosyl transferase, family 2
N7985_07040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7985_07045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7985_07050	COG2362	D-Aminopeptidase
N7985_07055	COG0601	transmembrane transport
N7985_07060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7985_07065	COG0444	Belongs to the ABC transporter superfamily
N7985_07070	COG4166	transmembrane transport
N7985_07075	COG1619	proteins homologs of microcin C7 resistance protein MccF
N7985_07080	COG4948	Mandelate Racemase Muconate Lactonizing
N7985_07085	COG0791	NLP P60 protein
N7985_07090	COG4608	Belongs to the ABC transporter superfamily
N7985_07095	COG2706	6-phosphogluconolactonase activity
N7985_07100	COG1834	amidinotransferase
N7985_07105	COG1607	acyl-coa hydrolase
N7985_07110	COG1017	nitric oxide dioxygenase activity
N7985_07110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7985_07120	COG2323	membrane
N7985_07125	COG2318	DinB family
N7985_07130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7985_07135	COG2076	Multidrug Resistance protein
N7985_07140	COG2076	Multidrug Resistance protein
N7985_07145	COG0788	formyltetrahydrofolate deformylase activity
N7985_07150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N7985_07155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N7985_07160	COG1764	response to oxidative stress
N7985_07165	COG1846	Transcriptional regulator
N7985_07170	COG1764	response to oxidative stress
N7985_07180	COG0590	tRNA wobble adenosine to inosine editing
N7985_07185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N7985_07190	COG1404	Belongs to the peptidase S8 family
N7985_07195	COG1366	Belongs to the anti-sigma-factor antagonist family
N7985_07200	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N7985_07205	COG1122	ATPase activity
N7985_07210	COG4721	ABC-type cobalt transport system, permease component
N7985_07220	COG0745	RESPONSE REGULATOR receiver
N7985_07225	COG3850	Histidine kinase
N7985_07225	COG5002	protein histidine kinase activity
N7985_07230	COG3212	peptidase
N7985_07235	COG3212	peptidase
N7985_07250	COG2239	Acts as a magnesium transporter
N7985_07255	COG0789	Transcriptional regulator
N7985_07270	COG1846	Transcriptional regulator
N7985_07275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N7985_07280	COG0726	polysaccharide deacetylase
N7985_07285	COG1408	metallophosphoesterase
N7985_07295	COG0463	Glycosyl transferase, family 2
N7985_07300	COG3285	dna ligase
N7985_07300	COG1793	dna ligase
N7985_07305	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
N7985_07310	COG3300	MHYT domain
N7985_07310	COG5001	Diguanylate cyclase
N7985_07315	COG0586	Pfam SNARE associated Golgi protein
N7985_07320	COG0861	Integral membrane protein TerC family
N7985_07325	COG1191	sigma factor activity
N7985_07345	COG0501	Belongs to the peptidase M48B family
N7985_07350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N7985_07365	COG3594	Acyltransferase
N7985_07370	COG5002	protein histidine kinase activity
N7985_07375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7985_07385	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N7985_07390	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
N7985_07395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N7985_07400	COG0436	Aminotransferase
N7985_07405	COG1850	ribulose-bisphosphate carboxylase activity
N7985_07410	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
N7985_07415	COG0235	Class ii aldolase
N7985_07420	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
N7985_07425	COG3339	Conserved Protein
N7985_07440	COG3852	Histidine kinase
N7985_07445	COG1846	Transcriptional regulator
N7985_07450	COG1360	Flagellar Motor Protein
N7985_07455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N7985_07460	COG0542	response to heat
N7985_07465	COG3949	Membrane
N7985_07470	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N7985_07475	COG0720	synthase
N7985_07480	COG0602	queuosine metabolic process
N7985_07485	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N7985_07490	COG1733	regulation of RNA biosynthetic process
N7985_07495	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_07500	COG4641	Protein conserved in bacteria
N7985_07500	COG1388	LysM domain
N7985_07505	COG1388	LysM domain
N7985_07510	COG3858	chitin binding
N7985_07520	COG4873	Protein conserved in bacteria
N7985_07530	COG3773	Cell wall hydrolase
N7985_07535	COG2244	polysaccharide biosynthetic process
N7985_07540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7985_07545	COG2217	Heavy metal translocating P-type atpase
N7985_07555	COG0006	proline dipeptidase activity
N7985_07560	COG1609	Transcriptional regulator
N7985_07565	COG3711	transcriptional antiterminator
N7985_07570	COG2190	(PTS) system
N7985_07570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_07570	COG1263	PTS System
N7985_07575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7985_07580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N7985_07590	COG1533	DNA photolyase activity
N7985_07595	COG0456	acetyltransferase
N7985_07600	COG0840	transmembrane signaling receptor activity
N7985_07605	COG2084	Dehydrogenase
N7985_07610	COG4257	antibiotic catabolic process
N7985_07615	COG2340	Cysteine-rich secretory protein family
N7985_07620	COG0768	penicillin binding
N7985_07625	COG4191	Histidine kinase
N7985_07630	COG0436	Aminotransferase
N7985_07640	COG0784	Response regulator, receiver
N7985_07640	COG0835	chemotaxis
N7985_07650	COG2814	Major facilitator Superfamily
N7985_07655	COG1376	ErfK ybiS ycfS ynhG family protein
N7985_07660	COG1408	metallophosphoesterase
N7985_07665	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_07670	COG2200	EAL domain
N7985_07675	COG4703	Protein of unknown function (DUF1797)
N7985_07680	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
N7985_07690	COG0517	IMP dehydrogenase activity
N7985_07695	COG0583	DNA-binding transcription factor activity
N7985_07700	COG0716	FMN binding
N7985_07710	COG0716	FMN binding
N7985_07715	COG2171	N-acyltransferase activity
N7985_07720	COG1473	amidohydrolase
N7985_07730	COG0668	transmembrane transport
N7985_07735	COG0450	alkyl hydroperoxide reductase
N7985_07740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7985_07755	COG0746	molybdenum cofactor guanylyltransferase activity
N7985_07760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N7985_07765	COG0303	'Molybdopterin
N7985_07770	COG1763	Mo-molybdopterin cofactor biosynthetic process
N7985_07775	COG0314	molybdopterin synthase activity
N7985_07780	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N7985_07785	COG1132	(ABC) transporter
N7985_07790	COG1132	(ABC) transporter
N7985_07800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7985_07805	COG1136	(ABC) transporter
N7985_07810	COG0577	efflux transmembrane transporter activity
N7985_07815	COG1349	DNA-binding transcription factor activity
N7985_07820	COG1105	Belongs to the carbohydrate kinase PfkB family
N7985_07825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7985_07825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7985_07825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7985_07830	COG0681	Belongs to the peptidase S26 family
N7985_07840	COG0488	(ABC) transporter
N7985_07845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N7985_07850	COG2309	aminopeptidase activity
N7985_07860	COG1077	Cell shape determining protein MreB Mrl
N7985_07865	COG2002	toxin-antitoxin pair type II binding
N7985_07870	COG3852	Histidine kinase
N7985_07875	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
N7985_07875	COG2105	PFAM AIG2 family protein
N7985_07880	COG0569	domain protein
N7985_07885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7985_07890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N7985_07895	COG5503	Protein of unknown function (DUF1447)
N7985_07900	COG0561	phosphatase activity
N7985_07905	COG0242	peptide deformylase activity
N7985_07915	COG0497	DNA recombination
N7985_07920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7985_07925	COG0022	dehydrogenase e1 component
N7985_07930	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7985_07935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7985_07940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7985_07950	COG1982	Orn Lys Arg decarboxylase major
N7985_07955	COG4476	Belongs to the UPF0223 family
N7985_07960	COG4493	Belongs to the UPF0637 family
N7985_07970	COG0483	inositol monophosphate 1-phosphatase activity
N7985_07980	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
N7985_08020	COG1217	gtp-binding protein TYPA
N7985_08030	COG4896	Protein conserved in bacteria
N7985_08040	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N7985_08045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N7985_08050	COG2066	Belongs to the glutaminase family
N7985_08055	COG4838	Belongs to the UPF0358 family
N7985_08060	COG0772	Belongs to the SEDS family
N7985_08065	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N7985_08070	COG1612	heme a metabolic process
N7985_08075	COG0109	protoheme IX farnesyltransferase activity
N7985_08080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7985_08080	COG2010	Cytochrome c
N7985_08085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7985_08090	COG1845	cytochrome c oxidase, subunit III
N7985_08095	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N7985_08100	COG3336	cytochrome c oxidase
N7985_08110	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
N7985_08115	COG2340	Cysteine-rich secretory protein family
N7985_08130	COG3679	Belongs to the UPF0342 family
N7985_08135	COG4471	UPF0298 protein
N7985_08140	COG0742	ribosomal rna small subunit methyltransferase
N7985_08145	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N7985_08150	COG3314	Sporulation integral membrane protein YlbJ
N7985_08155	COG1752	Esterase of the alpha-beta hydrolase superfamily
N7985_08160	COG3480	Lon protease (S16) C-terminal proteolytic domain
N7985_08165	COG1323	Belongs to the UPF0348 family
N7985_08175	COG1399	metal-binding, possibly nucleic acid-binding protein
N7985_08190	COG0454	-acetyltransferase
N7985_08195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N7985_08200	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
N7985_08205	COG2001	Belongs to the MraZ family
N7985_08210	COG0275	rRNA processing
N7985_08215	COG4839	cell division protein FtsL
N7985_08220	COG0768	penicillin binding
N7985_08225	COG0768	penicillin binding
N7985_08230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N7985_08235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N7985_08240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N7985_08245	COG0772	Belongs to the SEDS family
N7985_08250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N7985_08255	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N7985_08260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N7985_08265	COG3879	Bacterial protein of unknown function (DUF881)
N7985_08270	COG3879	Bacterial protein of unknown function (DUF881)
N7985_08275	COG3856	small basic protein
N7985_08280	COG0849	cell division
N7985_08285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N7985_08290	COG1404	Belongs to the peptidase S8 family
N7985_08290	COG4412	M6 family metalloprotease domain protein
N7985_08300	COG1191	sigma factor activity
N7985_08305	COG1191	sigma factor activity
N7985_08310	COG1119	ATPase activity
N7985_08315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7985_08320	COG1873	PFAM PRC-barrel domain
N7985_08325	COG1496	oxidoreductase activity
N7985_08330	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N7985_08335	COG1799	cell septum assembly
N7985_08340	COG0762	integral membrane protein
N7985_08345	COG2302	S4 RNA-binding domain
N7985_08350	COG3599	regulation of cell shape
N7985_08355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N7985_08360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N7985_08365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N7985_08370	COG0564	pseudouridine synthase activity
N7985_08375	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
N7985_08380	COG2233	PERMEase
N7985_08385	COG0540	Belongs to the ATCase OTCase family
N7985_08390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N7985_08395	COG0505	Belongs to the CarA family
N7985_08400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N7985_08405	COG0543	2 iron, 2 sulfur cluster binding
N7985_08410	COG0167	dihydroorotate dehydrogenase activity
N7985_08415	COG0284	orotidine-5'-phosphate decarboxylase activity
N7985_08420	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N7985_08425	COG0175	sulfate reduction
N7985_08430	COG0306	phosphate transporter
N7985_08435	COG2046	Belongs to the sulfate adenylyltransferase family
N7985_08440	COG0529	Catalyzes the synthesis of activated sulfate
N7985_08445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N7985_08450	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
N7985_08455	COG1648	precorrin-2 dehydrogenase activity
N7985_08460	COG1293	RNA-binding protein homologous to eukaryotic snRNP
N7985_08465	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N7985_08470	COG1561	YicC-like family, N-terminal region
N7985_08480	COG0194	GDP metabolic process
N7985_08485	COG1758	RNA polymerase activity
N7985_08490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N7985_08495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N7985_08500	COG0242	peptide deformylase activity
N7985_08505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N7985_08510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N7985_08510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7985_08515	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N7985_08520	COG0631	protein serine/threonine phosphatase activity
N7985_08525	COG0515	serine threonine protein kinase
N7985_08525	COG2815	serine threonine protein kinase
N7985_08530	COG1162	GTPase activity
N7985_08535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N7985_08540	COG1564	THIamine pyrophosphokinase
N7985_08550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N7985_08555	COG1302	Protein conserved in bacteria
N7985_08560	COG1461	Dihydroxyacetone kinase
N7985_08565	COG1760	l-serine dehydratase
N7985_08570	COG1760	l-serine dehydratase
N7985_08575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N7985_08580	COG1349	DNA-binding transcription factor activity
N7985_08580	COG2050	protein possibly involved in aromatic compounds catabolism
N7985_08585	COG0416	fatty acid biosynthetic process
N7985_08590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N7985_08595	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_08605	COG0571	ribonuclease III activity
N7985_08610	COG1196	nuclear chromosome segregation
N7985_08615	COG0552	protein localization to endoplasmic reticulum
N7985_08625	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
N7985_08630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N7985_08635	COG0228	four-way junction DNA binding
N7985_08640	COG1837	Belongs to the UPF0109 family
N7985_08650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N7985_08655	COG0336	Belongs to the RNA methyltransferase TrmD family
N7985_08660	COG0335	large ribosomal subunit rRNA binding
N7985_08665	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N7985_08670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N7985_08680	COG2257	FlhB HrpN YscU SpaS Family
N7985_08685	COG0045	succinate-CoA ligase (ADP-forming) activity
N7985_08690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N7985_08695	COG0758	DNA mediated transformation
N7985_08700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N7985_08705	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
N7985_08710	COG4974	Belongs to the 'phage' integrase family
N7985_08715	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N7985_08720	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N7985_08725	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N7985_08730	COG1815	bacterial-type flagellum-dependent cell motility
N7985_08735	COG1558	bacterial-type flagellum-dependent cell motility
N7985_08740	COG1677	Flagellar hook-basal body complex protein FliE
N7985_08745	COG1766	The M ring may be actively involved in energy transduction
N7985_08750	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7985_08755	COG1317	bacterial-type flagellum organization
N7985_08760	COG1157	protein secretion by the type III secretion system
N7985_08765	COG2882	bacterial-type flagellum organization
N7985_08770	COG3334	PFAM MgtE intracellular
N7985_08775	COG3144	bacterial-type flagellum assembly
N7985_08780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N7985_08785	COG4786	Flagellar basal body rod
N7985_08790	COG1582	Flagellar protein (FlbD)
N7985_08795	COG1580	Controls the rotational direction of flagella during chemotaxis
N7985_08800	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7985_08805	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7985_08805	COG1776	CheC inhibitor of MCP methylation
N7985_08810	COG2201	protein-glutamate methylesterase activity
N7985_08815	COG3190	flagellar
N7985_08820	COG1338	Plays a role in the flagellum-specific transport system
N7985_08825	COG1987	bacterial-type flagellum assembly
N7985_08830	COG1684	flagellar biosynthetic protein fliR
N7985_08835	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N7985_08840	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N7985_08845	COG1419	protein localization to endoplasmic reticulum
N7985_08850	COG0455	bacterial-type flagellum organization
N7985_08855	COG2201	protein-glutamate methylesterase activity
N7985_08860	COG0643	Histidine kinase
N7985_08860	COG2198	Histidine kinase
N7985_08865	COG0835	chemotaxis
N7985_08870	COG1776	CheC inhibitor of MCP methylation
N7985_08875	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N7985_08880	COG1191	sigma factor activity
N7985_08890	COG0052	Belongs to the universal ribosomal protein uS2 family
N7985_08895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N7985_08900	COG0528	UMP kinase activity
N7985_08905	COG0233	cytoplasmic translational termination
N7985_08910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N7985_08915	COG4589	Belongs to the CDS family
N7985_08920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N7985_08925	COG0750	zinc metalloprotease
N7985_08930	COG0442	prolyl-tRNA aminoacylation
N7985_08935	COG2176	DNA-directed DNA polymerase activity
N7985_08960	COG0779	Required for maturation of 30S ribosomal subunits
N7985_08965	COG0195	Participates in both transcription termination and antitermination
N7985_08970	COG2740	Nucleic-acid-binding protein implicated in transcription termination
N7985_08975	COG1358	cellular component organization or biogenesis
N7985_08980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N7985_08985	COG1550	Protein conserved in bacteria
N7985_08990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N7985_08995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N7985_09000	COG0196	riboflavin kinase activity
N7985_09005	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N7985_09010	COG1185	polyribonucleotide nucleotidyltransferase activity
N7985_09015	COG0726	polysaccharide deacetylase
N7985_09020	COG0612	Peptidase, M16
N7985_09025	COG1873	PFAM PRC-barrel domain
N7985_09030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7985_09035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N7985_09040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N7985_09045	COG0527	aspartate kinase activity
N7985_09050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7985_09055	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N7985_09060	COG0740	serine-type endopeptidase activity
N7985_09070	COG4980	gas vesicle protein
N7985_09070	COG1674	ftsk spoiiie
N7985_09075	COG2188	Transcriptional regulator
N7985_09080	COG2814	Major facilitator Superfamily
N7985_09085	COG0612	Peptidase, M16
N7985_09090	COG0612	Peptidase, M16
N7985_09095	COG0300	oxidoreductase activity
N7985_09110	COG1426	Protein conserved in bacteria
N7985_09115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N7985_09120	COG1058	Belongs to the CinA family
N7985_09120	COG1546	Belongs to the CinA family
N7985_09125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N7985_09130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7985_09135	COG1418	mRNA catabolic process
N7985_09140	COG1692	metallophosphoesterase
N7985_09145	COG2359	stage V sporulation protein S
N7985_09150	COG1063	alcohol dehydrogenase
N7985_09155	COG0156	8-amino-7-oxononanoate synthase activity
N7985_09160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7985_09165	COG4550	Control of competence regulator ComK, YlbF/YmcA
N7985_09175	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N7985_09180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N7985_09195	COG3226	Transcriptional regulator
N7985_09200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7985_09210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N7985_09215	COG3321	synthase
N7985_09220	COG2070	2-Nitropropane dioxygenase
N7985_09220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N7985_09225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7985_09230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7985_09235	COG3425	synthase
N7985_09240	COG1024	Enoyl-CoA hydratase
N7985_09245	COG1024	Enoyl-CoA hydratase
N7985_09250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_09250	COG0318	PFAM AMP-dependent synthetase and ligase
N7985_09250	COG0300	oxidoreductase activity
N7985_09250	COG3321	synthase
N7985_09250	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_09255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7985_09255	COG0300	oxidoreductase activity
N7985_09255	COG3321	synthase
N7985_09255	COG4221	oxidoreductase activity
N7985_09260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7985_09260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7985_09260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_09260	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_09260	COG3321	synthase
N7985_09265	COG4221	oxidoreductase activity
N7985_09265	COG3321	synthase
N7985_09265	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_09265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_09270	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N7985_09270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N7985_09270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7985_09270	COG3321	synthase
N7985_09275	COG2124	cytochrome p450
N7985_09285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7985_09290	COG1404	Belongs to the peptidase S8 family
N7985_09300	COG4195	phage-related replication protein
N7985_09305	COG1764	response to oxidative stress
N7985_09310	COG2076	Multidrug Resistance protein
N7985_09315	COG2076	Multidrug Resistance protein
N7985_09330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N7985_09335	COG1923	regulation of RNA biosynthetic process
N7985_09350	COG1780	Probably involved in ribonucleotide reductase function
N7985_09355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7985_09360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7985_09365	COG4112	unkown
N7985_09370	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7985_09375	COG0464	growth
N7985_09380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N7985_09385	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
N7985_09390	COG0789	Transcriptional regulator
N7985_09395	COG0174	glutamine synthetase
N7985_09420	COG4282	regulation of fungal-type cell wall biogenesis
N7985_09430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7985_09460	COG0135	phosphoribosylanthranilate isomerase activity
N7985_09465	COG2211	Major facilitator Superfamily
N7985_09470	COG3507	Belongs to the glycosyl hydrolase 43 family
N7985_09475	COG1940	carbohydrate kinase activity
N7985_09480	COG2115	Belongs to the xylose isomerase family
N7985_09485	COG1070	Carbohydrate kinase
N7985_09500	COG2814	Major facilitator Superfamily
N7985_09505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N7985_09520	COG0756	dUTP diphosphatase activity
N7985_09560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7985_09575	COG3832	glyoxalase III activity
N7985_09590	COG0697	spore germination
N7985_09595	COG0531	amino acid
N7985_09625	COG4195	phage-related replication protein
N7985_09635	COG0346	lactoylglutathione lyase activity
N7985_09645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N7985_09650	COG1388	LysM domain
N7985_09655	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7985_09660	COG4224	UPF0291 protein
N7985_09665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N7985_09675	COG3763	UPF0154 protein
N7985_09685	COG0785	Cytochrome C biogenesis protein
N7985_09690	COG2201	protein-glutamate methylesterase activity
N7985_09695	COG4846	Membrane protein involved in cytochrome C biogenesis
N7985_09705	COG0071	Belongs to the small heat shock protein (HSP20) family
N7985_09720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N7985_09725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7985_09745	COG0824	Thioesterase
N7985_09755	COG4841	protein insertion into membrane
N7985_09760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N7985_09765	COG1832	CoA-binding protein
N7985_09770	COG0187	DNA topoisomerase II activity
N7985_09775	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7985_09790	COG1115	amino acid carrier protein
N7985_09795	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
N7985_09805	COG5520	Belongs to the glycosyl hydrolase 30 family
N7985_09810	COG3507	Belongs to the glycosyl hydrolase 43 family
N7985_09815	COG2246	polysaccharide biosynthetic process
N7985_09820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7985_09825	COG0586	Pfam SNARE associated Golgi protein
N7985_09830	COG2404	hydrolase activity, acting on ester bonds
N7985_09835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7985_09840	COG1024	Enoyl-CoA hydratase
N7985_09845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7985_09850	COG0511	ligase activity, forming carbon-carbon bonds
N7985_09855	COG0439	Biotin carboxylase
N7985_09860	COG0318	PFAM AMP-dependent synthetase and ligase
N7985_09865	COG1960	acyl-CoA dehydrogenase activity
N7985_09875	COG1649	PFAM Uncharacterised BCR, COG1649
N7985_09885	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N7985_09885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_09890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_09895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_09900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_09905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_09910	COG2027	D-alanyl-D-alanine carboxypeptidase
N7985_09915	COG2017	converts alpha-aldose to the beta-anomer
N7985_09920	COG0534	Mate efflux family protein
N7985_09935	COG0582	viral genome integration into host DNA
N7985_09940	COG0166	Belongs to the GPI family
N7985_09945	COG0405	Gamma-glutamyltransferase
N7985_09950	COG0583	DNA-binding transcription factor activity
N7985_09960	COG0493	'glutamate synthase
N7985_09965	COG0067	glutamate synthase
N7985_09965	COG0069	glutamate synthase activity
N7985_09965	COG0070	glutamate synthase
N7985_09970	COG0583	DNA-binding transcription factor activity
N7985_09975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N7985_09980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7985_09990	COG0300	oxidoreductase activity
N7985_09995	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N7985_10005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7985_10020	COG1131	(ABC) transporter
N7985_10030	COG2814	Major facilitator Superfamily
N7985_10035	COG1070	Carbohydrate kinase
N7985_10040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N7985_10045	COG0243	molybdopterin cofactor binding
N7985_10055	COG2814	Major facilitator Superfamily
N7985_10060	COG0673	inositol 2-dehydrogenase activity
N7985_10065	COG1082	Xylose isomerase domain protein TIM barrel
N7985_10070	COG1609	Transcriptional regulator
N7985_10090	COG5278	phosphoserine phosphatase activity
N7985_10090	COG0840	transmembrane signaling receptor activity
N7985_10095	COG2368	4-hydroxyphenylacetate
N7985_10100	COG4305	rare lipoprotein A
N7985_10105	COG3619	membrane
N7985_10110	COG3866	Pectate lyase
N7985_10115	COG2135	peptidase activity
N7985_10125	COG2140	Oxalate decarboxylase
N7985_10150	COG2720	vancomycin resistance protein
N7985_10165	COG3739	integral membrane protein
N7985_10170	COG0583	DNA-binding transcription factor activity
N7985_10175	COG0697	spore germination
N7985_10185	COG0693	protein deglycase activity
N7985_10190	COG2367	Beta-lactamase
N7985_10210	COG3848	Pyruvate phosphate dikinase
N7985_10210	COG0574	Belongs to the PEP-utilizing enzyme family
N7985_10215	COG0726	polysaccharide deacetylase
N7985_10220	COG2314	TM2 domain
N7985_10275	COG0457	Tetratricopeptide repeat
N7985_10300	COG4282	regulation of fungal-type cell wall biogenesis
N7985_10305	COG1231	oxidoreductase activity
N7985_10310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7985_10315	COG0662	Cupin 2, conserved barrel domain protein
N7985_10315	COG2207	Transcriptional regulator
N7985_10320	COG0456	acetyltransferase
N7985_10325	COG1309	transcriptional regulator
N7985_10330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7985_10335	COG3708	Transcriptional regulator
N7985_10340	COG2378	regulation of single-species biofilm formation
N7985_10350	COG0640	Transcriptional regulator
N7985_10355	COG0741	lytic transglycosylase activity
N7985_10360	COG2322	membrane
N7985_10375	COG1619	proteins homologs of microcin C7 resistance protein MccF
N7985_10380	COG3239	Fatty acid desaturase
N7985_10385	COG4585	Histidine kinase
N7985_10390	COG2197	response regulator
N7985_10395	COG3584	3D domain protein
N7985_10395	COG1388	LysM domain
N7985_10400	COG0514	ATP-dependent DNA helicase (RecQ)
N7985_10410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7985_10415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N7985_10430	COG0071	Belongs to the small heat shock protein (HSP20) family
N7985_10455	COG1012	belongs to the aldehyde dehydrogenase family
N7985_10460	COG1657	PFAM Prenyltransferase squalene oxidase
N7985_10465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N7985_10470	COG0733	neurotransmitter:sodium symporter activity
N7985_10475	COG0385	Bile acid
N7985_10480	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7985_10485	COG0567	Dehydrogenase, E1 component
N7985_10490	COG4548	von Willebrand factor, type A
N7985_10495	COG0714	Associated with various cellular activities
N7985_10500	COG2032	superoxide dismutase activity
N7985_10505	COG1388	LysM domain
N7985_10505	COG0791	NLP P60 protein
N7985_10510	COG1819	glycosyl
N7985_10515	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N7985_10520	COG0534	Mate efflux family protein
N7985_10525	COG1366	Belongs to the anti-sigma-factor antagonist family
N7985_10530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N7985_10535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N7985_10545	COG2962	Rard protein
N7985_10560	COG2610	gluconate transmembrane transporter activity
N7985_10565	COG1942	4-Oxalocrotonate Tautomerase
N7985_10570	COG1733	regulation of RNA biosynthetic process
N7985_10575	COG0778	Nitroreductase
N7985_10580	COG0400	carboxylic ester hydrolase activity
N7985_10585	COG0346	lactoylglutathione lyase activity
N7985_10595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7985_10600	COG0793	Belongs to the peptidase S41A family
N7985_10600	COG3409	Peptidoglycan-binding domain 1 protein
N7985_10605	COG2226	methyltransferase
N7985_10615	COG1876	peptidase activity
N7985_10620	COG0813	purine-nucleoside phosphorylase activity
N7985_10635	COG0671	phosphoesterase, PA-phosphatase related
N7985_10655	COG4479	Belongs to the UPF0346 family
N7985_10665	COG1509	lysine 2,3-aminomutase activity
N7985_10670	COG0456	acetyltransferase
N7985_10675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7985_10680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7985_10685	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N7985_10690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7985_10705	COG0456	acetyltransferase
N7985_10710	COG0463	Glycosyl transferase, family 2
N7985_10725	COG4641	Protein conserved in bacteria
N7985_10730	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
N7985_10735	COG1086	Polysaccharide biosynthesis protein
N7985_10740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7985_10745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7985_10750	COG1846	Transcriptional regulator
N7985_10755	COG0534	Mate efflux family protein
N7985_10765	COG4698	Protein conserved in bacteria
N7985_10770	COG2755	lipolytic protein G-D-S-L family
N7985_10775	COG1999	signal sequence binding
N7985_10785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7985_10790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N7985_10795	COG1272	protein, Hemolysin III
N7985_10800	COG0204	Acyl-transferase
N7985_10805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7985_10810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N7985_10820	COG2521	methyltransferase
N7985_10820	COG2136	Putative SAM-dependent methyltransferase
N7985_10830	COG0129	dihydroxy-acid dehydratase activity
N7985_10835	COG1413	lyase activity
N7985_10840	COG1418	mRNA catabolic process
N7985_10845	COG0386	Belongs to the glutathione peroxidase family
N7985_10850	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
N7985_10855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N7985_10865	COG1278	Cold shock
N7985_10885	COG0328	RNA-DNA hybrid ribonuclease activity
N7985_10890	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N7985_10895	COG0328	RNA-DNA hybrid ribonuclease activity
N7985_10905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7985_10920	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N7985_10930	COG1755	Isoprenylcysteine carboxyl methyltransferase
N7985_10935	COG3424	synthase
N7985_10940	COG2233	PERMEase
N7985_10945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7985_10950	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N7985_10960	COG0800	Aldolase
N7985_10965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7985_10970	COG1609	Transcriptional regulator
N7985_10975	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
N7985_10980	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_10985	COG1199	ATP-dependent helicase activity
N7985_11000	COG0116	Belongs to the methyltransferase superfamily
N7985_11015	COG4474	Belongs to the UPF0398 family
N7985_11030	COG3359	exonuclease
N7985_11035	COG1111	helicase
N7985_11035	COG1205	dead DEAH box helicase
N7985_11040	COG2190	(PTS) system
N7985_11045	COG0071	Belongs to the small heat shock protein (HSP20) family
N7985_11080	COG3331	DNA recombination
N7985_11085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7985_11085	COG4499	WXG100 protein secretion system (Wss), protein YukC
N7985_11095	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N7985_11100	COG3935	DnaD domain protein
N7985_11105	COG0017	Asparaginyl-tRNA synthetase
N7985_11110	COG0436	Aminotransferase
N7985_11115	COG5353	protein conserved in bacteria
N7985_11125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N7985_11125	COG1199	ATP-dependent helicase activity
N7985_11130	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
N7985_11135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N7985_11140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N7985_11145	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
N7985_11145	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
N7985_11150	COG0617	tRNA 3'-terminal CCA addition
N7985_11155	COG0438	transferase activity, transferring glycosyl groups
N7985_11160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N7985_11165	COG1803	Methylglyoxal synthase
N7985_11170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N7985_11175	COG1694	Mazg nucleotide pyrophosphohydrolase
N7985_11180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7985_11190	COG4347	Protein of unknown function (DUF1405)
N7985_11195	COG2010	Cytochrome c
N7985_11195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N7985_11200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N7985_11205	COG0723	plastoquinol--plastocyanin reductase activity
N7985_11215	COG5582	Belongs to the UPF0302 family
N7985_11220	COG0457	Tetratricopeptide repeat
N7985_11225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N7985_11230	COG0287	Prephenate dehydrogenase
N7985_11235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N7985_11245	COG0133	tryptophan synthase activity
N7985_11250	COG0135	phosphoribosylanthranilate isomerase activity
N7985_11260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N7985_11265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N7985_11270	COG4401	Chorismate mutase type I
N7985_11275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N7985_11280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N7985_11285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N7985_11290	COG0105	UTP biosynthetic process
N7985_11295	COG0142	geranyltranstransferase activity
N7985_11300	COG2226	methyltransferase
N7985_11305	COG0142	geranyltranstransferase activity
N7985_11315	COG0302	gtp cyclohydrolase
N7985_11320	COG0776	regulation of translation
N7985_11325	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N7985_11340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N7985_11345	COG1160	GTP binding
N7985_11370	COG1304	FMN binding
N7985_11375	COG0539	negative regulation of cytoplasmic translation
N7985_11380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N7985_11390	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
N7985_11395	COG2959	enzyme of heme biosynthesis
N7985_11400	COG3773	Cell wall hydrolase
N7985_11400	COG3409	Peptidoglycan-binding domain 1 protein
N7985_11405	COG2339	peptidase activity
N7985_11410	COG0492	ferredoxin-NADP+ reductase activity
N7985_11415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7985_11420	COG4862	establishment of competence for transformation
N7985_11425	COG1408	metallophosphoesterase
N7985_11435	COG1388	LysM domain
N7985_11440	COG1266	CAAX protease self-immunity
N7985_11445	COG0514	ATP-dependent DNA helicase (RecQ)
N7985_11450	COG4955	Helix-turn-helix domain
N7985_11455	COG1141	Ferredoxin
N7985_11460	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
N7985_11465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N7985_11470	COG0710	3-dehydroquinate dehydratase activity
N7985_11480	COG1595	DNA-templated transcription, initiation
N7985_11485	COG5002	protein histidine kinase activity
N7985_11490	COG0745	RESPONSE REGULATOR receiver
N7985_11495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N7985_11500	COG1333	cytochrome c biogenesis protein
N7985_11505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7985_11510	COG1187	pseudouridine synthase activity
N7985_11515	COG0700	Nucleoside recognition
N7985_11520	COG2715	membrane protein required for spore maturation
N7985_11525	COG1686	Belongs to the peptidase S11 family
N7985_11535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7985_11540	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N7985_11545	COG1547	Domain of unknown function (DUF309)
N7985_11550	COG0456	acetyltransferase
N7985_11555	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N7985_11560	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7985_11560	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7985_11565	COG0307	riboflavin synthase, alpha
N7985_11570	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7985_11570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7985_11580	COG0681	Belongs to the peptidase S26 family
N7985_11600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N7985_11605	COG4086	secreted protein
N7985_11610	COG0019	diaminopimelate decarboxylase activity
N7985_11615	COG0697	spore germination
N7985_11630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7985_11650	COG1191	sigma factor activity
N7985_11655	COG2172	sigma factor antagonist activity
N7985_11660	COG1366	Belongs to the anti-sigma-factor antagonist family
N7985_11665	COG1686	Belongs to the peptidase S11 family
N7985_11670	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
N7985_11675	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N7985_11680	COG4974	Belongs to the 'phage' integrase family
N7985_11690	COG0735	belongs to the Fur family
N7985_11695	COG1300	Membrane
N7985_11705	COG0281	malic enzyme
N7985_11710	COG1757	Na H antiporter
N7985_11715	COG1027	Aspartate ammonia-lyase
N7985_11720	COG0252	asparaginase activity
N7985_11725	COG1396	sequence-specific DNA binding
N7985_11730	COG1379	DNA repair
N7985_11735	COG0494	nUDIX hydrolase
N7985_11745	COG0667	Aldo Keto reductase
N7985_11755	COG1073	alpha beta
N7985_11765	COG4918	Iron-sulphur cluster biosynthesis
N7985_11770	COG0456	acetyltransferase
N7985_11770	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N7985_11775	COG2329	Antibiotic biosynthesis monooxygenase
N7985_11780	COG0456	acetyltransferase
N7985_11790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7985_11800	COG2211	Major facilitator Superfamily
N7985_11810	COG0346	lactoylglutathione lyase activity
N7985_11815	COG1072	(Pantothenic acid kinase))
N7985_11820	COG3048	D-serine ammonia-lyase activity
N7985_11825	COG0300	oxidoreductase activity
N7985_11830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7985_11835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7985_11840	COG4187	Peptidase family M20/M25/M40
N7985_11845	COG1902	pentaerythritol trinitrate reductase activity
N7985_11850	COG0596	Alpha beta hydrolase
N7985_11860	COG1234	tRNA 3'-trailer cleavage
N7985_11865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N7985_11870	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N7985_11875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7985_11885	COG0706	membrane insertase activity
N7985_11890	COG3361	conserved protein (COG2071)
N7985_11895	COG2195	Cleaves the N-terminal amino acid of tripeptides
N7985_11900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7985_11905	COG0346	lactoylglutathione lyase activity
N7985_11915	COG1376	ErfK ybiS ycfS ynhG family protein
N7985_11920	COG4129	membrane
N7985_11925	COG1126	abc transporter atp-binding protein
N7985_11930	COG0765	amino acid transport
N7985_11935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7985_11945	COG1597	lipid kinase activity
N7985_11950	COG2814	Major facilitator Superfamily
N7985_11955	COG0789	Transcriptional regulator
N7985_11955	COG4978	Transcriptional regulator
N7985_11960	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7985_11965	COG0022	dehydrogenase e1 component
N7985_11970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7985_11975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7985_11980	COG3426	butyrate kinase activity
N7985_11985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7985_11990	COG0280	phosphate acetyltransferase
N7985_11995	COG3829	transcription factor binding
N7985_11995	COG3290	protein histidine kinase activity
N7985_12005	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N7985_12010	COG2079	MmgE PrpD family protein
N7985_12015	COG0372	Belongs to the citrate synthase family
N7985_12020	COG1960	acyl-CoA dehydrogenase activity
N7985_12025	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7985_12030	COG0183	Belongs to the thiolase family
N7985_12035	COG0584	glycerophosphoryl diester phosphodiesterase
N7985_12040	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7985_12055	COG1902	pentaerythritol trinitrate reductase activity
N7985_12060	COG0745	RESPONSE REGULATOR receiver
N7985_12065	COG0750	zinc metalloprotease
N7985_12070	COG0497	DNA recombination
N7985_12075	COG1438	arginine binding
N7985_12080	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
N7985_12085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N7985_12090	COG0142	geranyltranstransferase activity
N7985_12095	COG1722	exodeoxyribonuclease VII activity
N7985_12100	COG1570	exodeoxyribonuclease VII activity
N7985_12105	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N7985_12110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7985_12115	COG1302	Protein conserved in bacteria
N7985_12120	COG0439	Biotin carboxylase
N7985_12125	COG0511	ligase activity, forming carbon-carbon bonds
N7985_12165	COG3854	ATPases associated with a variety of cellular activities
N7985_12175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N7985_12180	COG0006	proline dipeptidase activity
N7985_12185	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N7985_12195	COG3872	metal-dependent enzyme
N7985_12205	COG1752	Esterase of the alpha-beta hydrolase superfamily
N7985_12210	COG1321	iron dependent repressor
N7985_12215	COG0095	Lipoate-protein ligase
N7985_12220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N7985_12225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N7985_12230	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N7985_12235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7985_12240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N7985_12255	COG1396	sequence-specific DNA binding
N7985_12265	COG0681	Belongs to the peptidase S26 family
N7985_12290	COG4940	Competence protein ComGF
N7985_12300	COG4970	Tfp pilus assembly protein FimT
N7985_12305	COG4537	Required for transformation and DNA binding
N7985_12310	COG1459	type II secretion system
N7985_12315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N7985_12320	COG0598	Magnesium transport protein CorA
N7985_12325	COG1253	flavin adenine dinucleotide binding
N7985_12330	COG1366	Belongs to the anti-sigma-factor antagonist family
N7985_12340	COG1393	Belongs to the ArsC family
N7985_12350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7985_12360	COG0011	TIGRFAM Protein of
N7985_12370	COG2866	Carboxypeptidase
N7985_12375	COG1368	sulfuric ester hydrolase activity
N7985_12380	COG1940	carbohydrate kinase activity
N7985_12385	COG4483	Protein conserved in bacteria
N7985_12390	COG0457	Tetratricopeptide repeat
N7985_12390	COG0705	Rhomboid family
N7985_12400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N7985_12410	COG0438	transferase activity, transferring glycosyl groups
N7985_12425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N7985_12430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7985_12435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7985_12440	COG0581	inorganic phosphate transmembrane transporter activity
N7985_12445	COG0573	inorganic phosphate transmembrane transporter activity
N7985_12450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N7985_12455	COG0768	penicillin binding
N7985_12460	COG0477	Major facilitator Superfamily
N7985_12465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N7985_12470	COG2839	Protein conserved in bacteria
N7985_12475	COG5521	maltodextrose utilization protein MalA
N7985_12480	COG1388	LysM domain
N7985_12485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N7985_12490	COG4709	membrane
N7985_12495	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
N7985_12500	COG0735	belongs to the Fur family
N7985_12505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7985_12515	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N7985_12520	COG0513	Belongs to the DEAD box helicase family
N7985_12530	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N7985_12535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N7985_12540	COG2384	SAM-dependent methyltransferase
N7985_12545	COG2010	Cytochrome c
N7985_12550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N7985_12555	COG0358	DNA primase activity
N7985_12560	COG1671	Belongs to the UPF0178 family
N7985_12565	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N7985_12570	COG0517	IMP dehydrogenase activity
N7985_12575	COG0751	glycine-tRNA ligase activity
N7985_12580	COG0752	glycyl-tRNA synthetase alpha subunit
N7985_12585	COG1381	Involved in DNA repair and RecF pathway recombination
N7985_12595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N7985_12600	COG0295	cytidine deaminase activity
N7985_12605	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N7985_12610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N7985_12615	COG1480	7TM receptor with intracellular HD hydrolase
N7985_12620	COG1702	phosphate starvation-inducible protein PhoH
N7985_12625	COG0561	phosphatase activity
N7985_12640	COG4864	UPF0365 protein
N7985_12645	COG1030	water channel activity
N7985_12650	COG1610	YqeY-like protein
N7985_12660	COG1283	sodium-dependent phosphate transmembrane transporter activity
N7985_12665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7985_12670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N7985_12675	COG2264	protein methyltransferase activity
N7985_12680	COG0484	heat shock protein binding
N7985_12685	COG0443	Heat shock 70 kDa protein
N7985_12690	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N7985_12695	COG1420	regulation of RNA biosynthetic process
N7985_12700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7985_12705	COG0481	GTPase activity
N7985_12715	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7985_12720	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
N7985_12725	COG0268	Binds directly to 16S ribosomal RNA
N7985_12730	COG1466	dna polymerase III delta subunit
N7985_12745	COG0658	competence protein
N7985_12745	COG2333	competence protein COMEC
N7985_12750	COG2131	deaminase
N7985_12755	COG1596	polysaccharide export
N7985_12755	COG1555	photosystem II stabilization
N7985_12760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7985_12765	COG2226	methyltransferase
N7985_12770	COG0799	negative regulation of ribosome biogenesis
N7985_12775	COG1713	HD superfamily hydrolase involved in NAD metabolism
N7985_12780	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N7985_12785	COG1534	Rna-binding protein
N7985_12790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N7985_12795	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N7985_12800	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
N7985_12810	COG2755	lipolytic protein G-D-S-L family
N7985_12815	COG5632	N-Acetylmuramoyl-L-alanine amidase
N7985_12815	COG3409	Peptidoglycan-binding domain 1 protein
N7985_12820	COG0398	Pfam SNARE associated Golgi protein
N7985_12825	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
N7985_12835	COG3209	COG3209 Rhs family protein
N7985_12845	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7985_12855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7985_12860	COG0798	PFAM Bile acid sodium symporter
N7985_12865	COG0346	lactoylglutathione lyase activity
N7985_12870	COG0640	Transcriptional regulator
N7985_12875	COG3403	YqcI/YcgG family
N7985_12880	COG0457	Tetratricopeptide repeat
N7985_12895	COG5444	nuclease activity
N7985_12920	COG3409	Peptidoglycan-binding domain 1 protein
N7985_12920	COG5632	N-Acetylmuramoyl-L-alanine amidase
N7985_12925	COG4824	toxin secretion phage lysis holin
N7985_12955	COG3778	Protein conserved in bacteria
N7985_12960	COG3299	homolog of phage Mu protein gp47
N7985_12965	COG3628	GPW Gp25 family protein
N7985_12975	COG4193	domain, Protein
N7985_12980	COG1652	LysM domain
N7985_12985	COG5280	Phage tail tape measure protein TP901
N7985_12985	COG3953	SLT domain
N7985_13050	COG4653	Phage capsid family
N7985_13055	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N7985_13065	COG2369	cell adhesion
N7985_13070	COG5518	Phage portal protein
N7985_13075	COG1783	phage Terminase large subunit
N7985_13080	COG5484	DNA packaging
N7985_13090	COG3677	Transposase
N7985_13105	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
N7985_13115	COG1484	DNA-dependent DNA replication
N7985_13120	COG3935	DnaD domain protein
N7985_13125	COG3723	Recombinational DNA repair protein, rece pathway
N7985_13130	COG5377	YqaJ viral recombinase family
N7985_13160	COG1476	TRANSCRIPTIONal
N7985_13165	COG3620	sequence-specific DNA binding
N7985_13175	COG0563	adenylate kinase activity
N7985_13180	COG2856	Zn peptidase
N7985_13205	COG3223	Belongs to the PsiE family
N7985_13210	COG0642	Histidine kinase
N7985_13210	COG5002	protein histidine kinase activity
N7985_13215	COG0745	RESPONSE REGULATOR receiver
N7985_13220	COG2311	Membrane
N7985_13230	COG0454	-acetyltransferase
N7985_13235	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7985_13245	COG0730	response to heat
N7985_13250	COG0425	Belongs to the sulfur carrier protein TusA family
N7985_13265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N7985_13265	COG0425	Belongs to the sulfur carrier protein TusA family
N7985_13275	COG2210	Belongs to the sulfur carrier protein TusA family
N7985_13280	COG1937	Protein conserved in bacteria
N7985_13290	COG0662	Cupin 2, conserved barrel domain protein
N7985_13305	COG0789	Transcriptional regulator
N7985_13305	COG4978	Transcriptional regulator
N7985_13310	COG2814	Major facilitator Superfamily
N7985_13315	COG0456	acetyltransferase
N7985_13320	COG1253	flavin adenine dinucleotide binding
N7985_13330	COG0697	spore germination
N7985_13335	COG0583	DNA-binding transcription factor activity
N7985_13340	COG2072	flavoprotein involved in K transport
N7985_13345	COG1230	cation diffusion facilitator family transporter
N7985_13350	COG1942	4-Oxalocrotonate Tautomerase
N7985_13355	COG0583	DNA-binding transcription factor activity
N7985_13365	COG1114	Component of the transport system for branched-chain amino acids
N7985_13370	COG1687	branched-chain amino acid
N7985_13375	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N7985_13380	COG1522	sequence-specific DNA binding
N7985_13385	COG2732	(Barnase) inhibitor
N7985_13390	COG2124	cytochrome p450
N7985_13400	COG1335	isochorismatase
N7985_13415	COG2318	DinB family
N7985_13425	COG2070	2-Nitropropane dioxygenase
N7985_13430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N7985_13440	COG2186	Transcriptional regulator
N7985_13455	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_13460	COG3958	Transketolase
N7985_13465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N7985_13470	COG0477	Major facilitator Superfamily
N7985_13475	COG1846	Transcriptional regulator
N7985_13480	COG3443	Belongs to the bacterial solute-binding protein 9 family
N7985_13485	COG1595	DNA-templated transcription, initiation
N7985_13490	COG0667	Aldo Keto reductase
N7985_13495	COG2851	Citrate transporter
N7985_13500	COG0583	DNA-binding transcription factor activity
N7985_13505	COG2828	Protein conserved in bacteria
N7985_13510	COG3409	Peptidoglycan-binding domain 1 protein
N7985_13515	COG5566	PFAM Mor transcription activator
N7985_13520	COG0596	Alpha beta hydrolase
N7985_13525	COG4991	sh3 domain protein
N7985_13530	COG4991	sh3 domain protein
N7985_13540	COG0346	lactoylglutathione lyase activity
N7985_13550	COG5577	PFAM Coat F domain
N7985_13555	COG1063	alcohol dehydrogenase
N7985_13565	COG5577	PFAM Coat F domain
N7985_13570	COG0789	Transcriptional regulator
N7985_13580	COG1064	alcohol dehydrogenase
N7985_13585	COG0693	protein deglycase activity
N7985_13590	COG1621	beta-fructofuranosidase activity
N7985_13600	COG3716	PTS system mannose fructose sorbose family IID component
N7985_13605	COG3715	PTS system
N7985_13610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_13615	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7985_13620	COG3933	PFAM sigma-54 factor interaction domain-containing protein
N7985_13620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N7985_13630	COG1113	amino acid transport
N7985_13635	COG1280	lysine exporter protein (LysE YggA)
N7985_13640	COG1378	Sugar-specific transcriptional regulator TrmB
N7985_13645	COG1595	DNA-templated transcription, initiation
N7985_13655	COG2755	lipolytic protein G-D-S-L family
N7985_13655	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N7985_13665	COG2124	cytochrome p450
N7985_13665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N7985_13670	COG1309	transcriptional regulator
N7985_13675	COG2226	methyltransferase
N7985_13690	COG2116	formate transmembrane transporter activity
N7985_13695	COG5609	conserved protein (DUF2294)
N7985_13700	COG3383	formate dehydrogenase (NAD+) activity
N7985_13705	COG2427	Protein of unknown function (DUF1641)
N7985_13715	COG0626	cystathionine gamma-synthase activity
N7985_13720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7985_13725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N7985_13730	COG2226	methyltransferase
N7985_13745	COG0768	penicillin binding
N7985_13750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7985_13755	COG0572	uridine kinase
N7985_13760	COG0826	peptidase U32
N7985_13765	COG0826	peptidase U32
N7985_13770	COG4122	O-methyltransferase activity
N7985_13775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N7985_13780	COG3906	Belongs to the UPF0473 family
N7985_13785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N7985_13790	COG4472	Bacterial protein of unknown function (DUF965)
N7985_13795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N7985_13800	COG0628	permease
N7985_13805	COG1126	abc transporter atp-binding protein
N7985_13810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7985_13815	COG0765	amino acid transport
N7985_13820	COG0765	amino acid transport
N7985_13835	COG3881	PFAM PRC-barrel domain
N7985_13840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7985_13845	COG0457	Tetratricopeptide repeat
N7985_13850	COG0482	sulfurtransferase activity
N7985_13855	COG1104	cysteine desulfurase activity
N7985_13860	COG1959	2 iron, 2 sulfur cluster binding
N7985_13865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N7985_13870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N7985_13880	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N7985_13885	COG0124	histidyl-tRNA synthetase
N7985_13895	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7985_13895	COG4991	sh3 domain protein
N7985_13895	COG3103	Sh3 type 3 domain protein
N7985_13900	COG1490	D-aminoacyl-tRNA deacylase activity
N7985_13905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N7985_13910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7985_13915	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
N7985_13915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N7985_13920	COG5416	Lipopolysaccharide assembly protein A domain
N7985_13925	COG0490	domain, Protein
N7985_13930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N7985_13930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N7985_13940	COG2244	polysaccharide biosynthetic process
N7985_13945	COG2323	membrane
N7985_13955	COG1862	Preprotein translocase
N7985_13960	COG0343	queuine tRNA-ribosyltransferase activity
N7985_13965	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N7985_13975	COG2255	four-way junction helicase activity
N7985_13980	COG0632	four-way junction helicase activity
N7985_13990	COG2814	Major facilitator Superfamily
N7985_13995	COG0673	inositol 2-dehydrogenase activity
N7985_14000	COG2112	serine threonine protein kinase
N7985_14020	COG1115	amino acid carrier protein
N7985_14025	COG0217	transcriptional regulatory protein
N7985_14035	COG1388	LysM domain
N7985_14040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N7985_14045	COG0157	Belongs to the NadC ModD family
N7985_14050	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N7985_14055	COG1104	cysteine desulfurase activity
N7985_14060	COG1827	regulation of RNA biosynthetic process
N7985_14065	COG0077	Prephenate dehydratase
N7985_14070	COG4492	Belongs to the UPF0735 family
N7985_14075	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N7985_14080	COG3290	protein histidine kinase activity
N7985_14090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N7985_14095	COG2868	ribosomal protein
N7985_14100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N7985_14105	COG1994	Peptidase M50
N7985_14110	COG0739	heme binding
N7985_14115	COG2894	cell division
N7985_14120	COG0850	regulation of cytokinetic process
N7985_14125	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N7985_14135	COG1077	Cell shape determining protein MreB Mrl
N7985_14140	COG2003	Belongs to the UPF0758 family
N7985_14145	COG0424	maF-like protein
N7985_14155	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
N7985_14160	COG0285	dihydrofolate synthase activity
N7985_14165	COG0525	valine-tRNA ligase activity
N7985_14175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7985_14180	COG1388	LysM domain
N7985_14185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N7985_14190	COG0113	porphobilinogen synthase activity
N7985_14195	COG1587	Uroporphyrinogen-III synthase
N7985_14200	COG0181	hydroxymethylbilane synthase activity
N7985_14205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N7985_14210	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N7985_14220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
N7985_14225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N7985_14230	COG1067	ATP-dependent peptidase activity
N7985_14230	COG0470	DNA polymerase III
N7985_14235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N7985_14240	COG0544	peptidyl-prolyl cis-trans isomerase activity
N7985_14245	COG1477	protein flavinylation
N7985_14245	COG0457	Tetratricopeptide repeat
N7985_14250	COG0066	3-isopropylmalate dehydratase activity
N7985_14255	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N7985_14260	COG0473	3-isopropylmalate dehydrogenase activity
N7985_14265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7985_14270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N7985_14275	COG0440	acetolactate synthase activity
N7985_14280	COG0028	Belongs to the TPP enzyme family
N7985_14290	COG0454	-acetyltransferase
N7985_14295	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
N7985_14305	COG0622	Phosphoesterase
N7985_14310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N7985_14315	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N7985_14320	COG5401	PFAM Sporulation and spore germination
N7985_14325	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N7985_14330	COG1846	Transcriptional regulator
N7985_14335	COG2197	response regulator
N7985_14340	COG0824	Thioesterase
N7985_14345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N7985_14350	COG1053	succinate dehydrogenase
N7985_14355	COG2009	succinate dehydrogenase
N7985_14360	COG1719	4-vinyl reductase, 4VR
N7985_14365	COG0527	aspartate kinase activity
N7985_14370	COG0322	excinuclease ABC activity
N7985_14375	COG3118	belongs to the thioredoxin family
N7985_14380	COG3534	alpha-L-arabinofuranosidase
N7985_14385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N7985_14390	COG2086	electron transfer activity
N7985_14395	COG1024	Enoyl-CoA hydratase
N7985_14400	COG1309	transcriptional regulator
N7985_14405	COG0318	PFAM AMP-dependent synthetase and ligase
N7985_14410	COG3766	membrane
N7985_14415	COG1193	negative regulation of DNA recombination
N7985_14420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N7985_14420	COG1796	DNA polymerase
N7985_14425	COG1286	toxin biosynthetic process
N7985_14430	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
N7985_14435	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N7985_14440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7985_14440	COG0072	phenylalanine-tRNA ligase activity
N7985_14445	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N7985_14455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7985_14465	COG3835	regulator
N7985_14470	COG0277	FAD linked oxidase domain protein
N7985_14475	COG0247	lactate metabolic process
N7985_14480	COG0346	lactoylglutathione lyase activity
N7985_14490	COG1966	Carbon starvation protein
N7985_14495	COG3534	alpha-L-arabinofuranosidase
N7985_14500	COG0395	ABC-type sugar transport system, permease component
N7985_14505	COG1175	transmembrane transport
N7985_14510	COG1653	transport
N7985_14515	COG0371	Dehydrogenase
N7985_14520	COG0647	UMP catabolic process
N7985_14525	COG0235	Class ii aldolase
N7985_14530	COG1069	ribulokinase activity
N7985_14535	COG2160	L-arabinose isomerase activity
N7985_14540	COG3507	Belongs to the glycosyl hydrolase 43 family
N7985_14545	COG1363	Peptidase, m42
N7985_14555	COG3326	Membrane
N7985_14560	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N7985_14565	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N7985_14570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N7985_14580	COG1346	cytolysis
N7985_14585	COG1380	Effector of murein hydrolase LrgA
N7985_14590	COG3279	Response regulator of the LytR AlgR family
N7985_14595	COG3275	phosphorelay sensor kinase activity
N7985_14600	COG1011	Hydrolase
N7985_14605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N7985_14615	COG0398	Pfam SNARE associated Golgi protein
N7985_14620	COG1484	DNA-dependent DNA replication
N7985_14625	COG3611	Membrane attachment protein
N7985_14630	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N7985_14635	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
N7985_14640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N7985_14645	COG1733	regulation of RNA biosynthetic process
N7985_14650	COG2814	Major facilitator Superfamily
N7985_14655	COG0656	L-ascorbic acid biosynthetic process
N7985_14660	COG0237	dephospho-CoA kinase activity
N7985_14665	COG1971	Probably functions as a manganese efflux pump
N7985_14670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N7985_14675	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7985_14675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7985_14680	COG5002	protein histidine kinase activity
N7985_14685	COG0745	RESPONSE REGULATOR receiver
N7985_14690	COG0039	L-malate dehydrogenase activity
N7985_14695	COG0538	isocitrate dehydrogenase activity
N7985_14700	COG0372	Belongs to the citrate synthase family
N7985_14705	COG2707	UPF0756 membrane protein
N7985_14710	COG0628	permease
N7985_14715	COG3030	protein affecting phage T7 exclusion by the F plasmid
N7985_14720	COG0469	pyruvate kinase activity
N7985_14725	COG0205	6-phosphofructokinase activity
N7985_14730	COG0825	malonyl-CoA metabolic process
N7985_14735	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N7985_14740	COG0281	malic enzyme
N7985_14745	COG0587	DNA-directed DNA polymerase activity
N7985_14765	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N7985_14775	COG4109	DRTGG domain
N7985_14780	COG0730	response to heat
N7985_14785	COG1473	amidohydrolase
N7985_14790	COG0196	riboflavin kinase activity
N7985_14795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7985_14800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N7985_14805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7985_14810	COG1126	abc transporter atp-binding protein
N7985_14815	COG0765	amino acid transport
N7985_14820	COG0765	amino acid transport
N7985_14825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7985_14830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7985_14835	COG0454	-acetyltransferase
N7985_14840	COG0583	DNA-binding transcription factor activity
N7985_14845	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N7985_14850	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_14860	COG0165	Argininosuccinate lyase
N7985_14865	COG0137	argininosuccinate synthase activity
N7985_14870	COG0521	Mo-molybdopterin cofactor biosynthetic process
N7985_14875	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N7985_14885	COG0827	DNA restriction-modification system
N7985_14890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
N7985_14895	COG3874	Sporulation protein YtfJ
N7985_14905	COG1714	RDD family
N7985_14910	COG0616	signal peptide processing
N7985_14915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N7985_14920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
N7985_14925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7985_14935	COG0301	tRNA thio-modification
N7985_14940	COG1104	cysteine desulfurase activity
N7985_14945	COG1114	Component of the transport system for branched-chain amino acids
N7985_14950	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
N7985_14955	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N7985_14960	COG1309	transcriptional regulator
N7985_14965	COG1956	GAF domain-containing protein
N7985_14970	COG2203	Gaf domain
N7985_14970	COG2199	diguanylate cyclase activity
N7985_14975	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N7985_14985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N7985_14990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7985_14995	COG0454	-acetyltransferase
N7985_15000	COG0517	IMP dehydrogenase activity
N7985_15005	COG0123	including yeast histone deacetylase and acetoin utilization protein
N7985_15010	COG1360	Flagellar Motor Protein
N7985_15015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N7985_15020	COG1609	Transcriptional regulator
N7985_15025	COG1605	Chorismate mutase
N7985_15025	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
N7985_15030	COG3118	belongs to the thioredoxin family
N7985_15035	COG4980	gas vesicle protein
N7985_15040	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N7985_15045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N7985_15050	COG1674	ftsk spoiiie
N7985_15055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7985_15060	COG4848	Belongs to the UPF0354 family
N7985_15065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7985_15080	COG1363	Peptidase, m42
N7985_15085	COG5584	Small secreted protein
N7985_15090	COG0281	malic enzyme
N7985_15095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7985_15100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N7985_15110	COG0510	thiamine kinase activity
N7985_15115	COG1523	belongs to the glycosyl hydrolase 13 family
N7985_15120	COG1597	lipid kinase activity
N7985_15130	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N7985_15135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7985_15140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7985_15145	COG2252	PERMEase
N7985_15150	COG4473	ABC transporter
N7985_15155	COG1131	(ABC) transporter
N7985_15160	COG1349	DNA-binding transcription factor activity
N7985_15165	COG1187	pseudouridine synthase activity
N7985_15170	COG2244	polysaccharide biosynthetic process
N7985_15175	COG2081	HI0933 family
N7985_15180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N7985_15190	COG5578	integral membrane protein
N7985_15195	COG0673	inositol 2-dehydrogenase activity
N7985_15200	COG1653	transport
N7985_15205	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N7985_15210	COG4209	transmembrane transport
N7985_15215	COG2207	Transcriptional regulator
N7985_15220	COG1653	transport
N7985_15225	COG0395	ABC-type sugar transport system, permease component
N7985_15230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7985_15235	COG2124	cytochrome p450
N7985_15240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N7985_15250	COG0156	8-amino-7-oxononanoate synthase activity
N7985_15255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7985_15265	COG1073	alpha beta
N7985_15270	COG1609	Transcriptional regulator
N7985_15275	COG1653	transport
N7985_15280	COG1175	transmembrane transport
N7985_15285	COG0395	ABC-type sugar transport system, permease component
N7985_15290	COG1486	melibiose metabolic process
N7985_15295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N7985_15300	COG0495	leucyl-tRNA aminoacylation
N7985_15310	COG2202	Pas domain
N7985_15310	COG1366	Belongs to the anti-sigma-factor antagonist family
N7985_15315	COG2814	Major facilitator Superfamily
N7985_15320	COG2433	Pfam Transposase IS66
N7985_15325	COG0577	efflux transmembrane transporter activity
N7985_15330	COG1136	(ABC) transporter
N7985_15335	COG2205	protein histidine kinase activity
N7985_15340	COG0745	RESPONSE REGULATOR receiver
N7985_15345	COG0577	efflux transmembrane transporter activity
N7985_15350	COG1136	(ABC) transporter
N7985_15365	COG1131	(ABC) transporter
N7985_15370	COG1725	Transcriptional regulator
N7985_15385	COG1242	4 iron, 4 sulfur cluster binding
N7985_15390	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
N7985_15400	COG2267	carboxylic ester hydrolase activity
N7985_15405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N7985_15410	COG1113	amino acid transport
N7985_15415	COG0367	asparagine synthase
N7985_15420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N7985_15425	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N7985_15435	COG1506	peptidase
N7985_15440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7985_15445	COG1116	anion transmembrane transporter activity
N7985_15450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7985_15455	COG0494	nUDIX hydrolase
N7985_15460	COG4824	toxin secretion phage lysis holin
N7985_15465	COG0783	Belongs to the Dps family
N7985_15480	COG1854	S-ribosylhomocysteine lyase activity
N7985_15485	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N7985_15490	COG0288	reversible hydration of carbon dioxide
N7985_15495	COG0254	rRNA binding
N7985_15500	COG1271	oxidase subunit
N7985_15505	COG1294	oxidase, subunit
N7985_15515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7985_15520	COG1321	iron dependent repressor
N7985_15520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7985_15525	COG1121	(ABC) transporter
N7985_15530	COG0803	Belongs to the bacterial solute-binding protein 9 family
N7985_15535	COG4948	Mandelate Racemase Muconate Lactonizing
N7985_15540	COG0318	PFAM AMP-dependent synthetase and ligase
N7985_15545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
N7985_15550	COG0596	Alpha beta hydrolase
N7985_15555	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N7985_15560	COG1169	isochorismate synthase
N7985_15565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N7985_15570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7985_15575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N7985_15580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7985_15585	COG0438	transferase activity, transferring glycosyl groups
N7985_15595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7985_15600	COG0438	transferase activity, transferring glycosyl groups
N7985_15605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7985_15610	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
N7985_15615	COG0058	SHG alpha-glucan phosphorylase activity
N7985_15620	COG0297	glycogen (starch) synthase activity
N7985_15625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N7985_15630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N7985_15635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N7985_15760	COG3859	Proton-coupled thiamine transporter YuaJ
N7985_15765	COG1247	-acetyltransferase
N7985_15770	COG2268	Band 7 protein
N7985_15775	COG1585	Membrane protein implicated in regulation of membrane protease activity
N7985_15780	COG2318	DinB family
N7985_15790	COG1454	alcohol dehydrogenase
N7985_15795	COG1012	belongs to the aldehyde dehydrogenase family
N7985_15800	COG1510	regulation of RNA biosynthetic process
N7985_15810	COG0569	domain protein
N7985_15815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N7985_15820	COG4682	membrane
N7985_15825	COG1705	Flagellar rod assembly protein muramidase FlgJ
N7985_15830	COG0477	Major facilitator Superfamily
N7985_15835	COG5553	Cysteine dioxygenase type I
N7985_15845	COG1968	undecaprenyl-diphosphatase activity
N7985_15850	COG0628	permease
N7985_15855	COG0673	inositol 2-dehydrogenase activity
N7985_15860	COG4806	L-rhamnose isomerase
N7985_15865	COG3254	rhamnose metabolic process
N7985_15870	COG1070	Carbohydrate kinase
N7985_15875	COG1349	DNA-binding transcription factor activity
N7985_15880	COG3347	Dehydrogenase
N7985_15880	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_15885	COG0840	transmembrane signaling receptor activity
N7985_15890	COG0840	transmembrane signaling receptor activity
N7985_15895	COG0840	transmembrane signaling receptor activity
N7985_15900	COG0840	transmembrane signaling receptor activity
N7985_15915	COG0432	Pfam Uncharacterised protein family UPF0047
N7985_15925	COG0366	Alpha amylase catalytic
N7985_15930	COG1253	flavin adenine dinucleotide binding
N7985_15935	COG2738	Putative neutral zinc metallopeptidase
N7985_15950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N7985_15965	COG0166	Belongs to the GPI family
N7985_15970	COG1979	alcohol dehydrogenase
N7985_15975	COG1979	alcohol dehydrogenase
N7985_15980	COG2155	Conserved Protein
N7985_15985	COG1098	S1 RNA binding domain
N7985_15990	COG0436	Aminotransferase
N7985_15995	COG1522	sequence-specific DNA binding
N7985_16000	COG2267	carboxylic ester hydrolase activity
N7985_16010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
N7985_16015	COG2205	protein histidine kinase activity
N7985_16025	COG5018	Exonuclease
N7985_16035	COG2814	Major facilitator Superfamily
N7985_16040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7985_16045	COG3011	Protein conserved in bacteria
N7985_16055	COG3290	protein histidine kinase activity
N7985_16060	COG4565	transcriptional regulatory protein
N7985_16065	COG1744	ABC transporter substrate-binding protein PnrA-like
N7985_16070	COG3845	ABC transporter
N7985_16075	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7985_16080	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7985_16085	COG3493	citrate carrier protein
N7985_16095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N7985_16095	COG2111	Na H antiporter
N7985_16100	COG2111	Na H antiporter
N7985_16105	COG1006	Multisubunit Na H antiporter MnhC subunit
N7985_16110	COG0651	ATP synthesis coupled electron transport
N7985_16115	COG1863	multisubunit Na H antiporter MnhE subunit
N7985_16120	COG2212	antiporter activity
N7985_16125	COG1320	monovalent cation:proton antiporter activity
N7985_16130	COG2050	protein possibly involved in aromatic compounds catabolism
N7985_16135	COG2197	response regulator
N7985_16140	COG4585	Histidine kinase
N7985_16150	COG0142	geranyltranstransferase activity
N7985_16170	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N7985_16175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N7985_16180	COG1335	isochorismatase
N7985_16185	COG5506	Protein of unknown function (DUF1694)
N7985_16200	COG0628	permease
N7985_16215	COG1418	mRNA catabolic process
N7985_16220	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_16230	COG1511	domain protein
N7985_16235	COG1674	ftsk spoiiie
N7985_16235	COG0433	COG0433 Predicted ATPase
N7985_16240	COG4499	WXG100 protein secretion system (Wss), protein YukC
N7985_16245	COG5417	Belongs to the EsaB family
N7985_16250	COG4842	Belongs to the WXG100 family
N7985_16255	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N7985_16255	COG2508	Transcriptional regulator
N7985_16260	COG0686	Belongs to the AlaDH PNT family
N7985_16265	COG5634	Uncharacterized conserved protein (DUF2278)
N7985_16270	COG3251	PFAM MbtH domain protein
N7985_16275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_16280	COG3433	isochorismatase activity
N7985_16280	COG1535	isochorismatase
N7985_16285	COG1021	2,3-dihydroxybenzoate-AMP ligase
N7985_16290	COG1169	isochorismate synthase
N7985_16295	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_16300	COG2819	hydrolase of the alpha beta superfamily
N7985_16305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N7985_16310	COG1268	BioY protein
N7985_16315	COG2056	Na+-H+ antiporter family
N7985_16320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N7985_16325	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
N7985_16330	COG3584	3D domain protein
N7985_16345	COG1252	NADH dehydrogenase
N7985_16350	COG0492	ferredoxin-NADP+ reductase activity
N7985_16360	COG0516	GMP reductase activity
N7985_16365	COG2808	Putative FMN-binding domain
N7985_16370	COG0456	acetyltransferase
N7985_16375	COG0316	Belongs to the HesB IscA family
N7985_16380	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N7985_16385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N7985_16390	COG4844	belongs to the
N7985_16395	COG1252	NADH dehydrogenase
N7985_16400	COG4837	Protein of unknown function (DUF1462)
N7985_16405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N7985_16410	COG1506	peptidase
N7985_16410	COG0823	Involved in the tonB-independent uptake of proteins
N7985_16410	COG4946	Tricorn protease homolog
N7985_16415	COG0083	homoserine kinase activity
N7985_16420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N7985_16425	COG0460	homoserine dehydrogenase
N7985_16430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7985_16435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N7985_16440	COG0647	UMP catabolic process
N7985_16445	COG2445	Protein of unknown function DUF86
N7985_16450	COG4470	Protein conserved in bacteria
N7985_16460	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N7985_16465	COG0739	heme binding
N7985_16475	COG3377	Domain of unknown function (DUF1805)
N7985_16480	COG0737	Belongs to the 5'-nucleotidase family
N7985_16485	COG0730	response to heat
N7985_16490	COG1801	Protein of unknown function DUF72
N7985_16500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N7985_16505	COG2508	Transcriptional regulator
N7985_16510	COG2233	PERMEase
N7985_16515	COG2233	PERMEase
N7985_16520	COG3195	allantoin biosynthetic process
N7985_16520	COG3648	Uricase
N7985_16525	COG2351	hydroxyisourate hydrolase activity
N7985_16535	COG2080	2 iron, 2 sulfur cluster binding
N7985_16540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N7985_16545	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
N7985_16550	COG2068	MobA-Related Protein
N7985_16555	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N7985_16560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N7985_16565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7985_16575	COG2356	endonuclease I
N7985_16580	COG3842	ATPase activity
N7985_16585	COG2188	Transcriptional regulator
N7985_16590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7985_16595	COG0395	ABC-type sugar transport system, permease component
N7985_16600	COG1175	transmembrane transport
N7985_16605	COG1653	transport
N7985_16610	COG2222	sugar isomerase
N7985_16615	COG0322	excinuclease ABC activity
N7985_16620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7985_16635	COG0346	lactoylglutathione lyase activity
N7985_16640	COG0640	Transcriptional regulator
N7985_16645	COG0719	Fe-S assembly protein
N7985_16650	COG0822	iron-sulfur transferase activity
N7985_16655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N7985_16660	COG0719	Fe-S assembly protein
N7985_16665	COG0396	ATPase activity
N7985_16675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7985_16680	COG1464	Belongs to the NlpA lipoprotein family
N7985_16685	COG2011	ABC-type metal ion transport system permease component
N7985_16690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N7985_16700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7985_16705	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N7985_16715	COG0509	glycine decarboxylation via glycine cleavage system
N7985_16720	COG1393	Belongs to the ArsC family
N7985_16725	COG1960	acyl-CoA dehydrogenase activity
N7985_16730	COG0183	Belongs to the thiolase family
N7985_16735	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7985_16735	COG1024	Enoyl-CoA hydratase
N7985_16745	COG0506	proline dehydrogenase activity
N7985_16755	COG5577	PFAM Coat F domain
N7985_16760	COG1846	Transcriptional regulator
N7985_16765	COG0477	Major facilitator Superfamily
N7985_16770	COG1942	4-Oxalocrotonate Tautomerase
N7985_16780	COG0583	DNA-binding transcription factor activity
N7985_16790	COG1120	ATPase activity
N7985_16805	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_16810	COG0783	Belongs to the Dps family
N7985_16815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7985_16820	COG0745	RESPONSE REGULATOR receiver
N7985_16825	COG2770	Histidine kinase
N7985_16825	COG2205	protein histidine kinase activity
N7985_16835	COG1309	transcriptional regulator
N7985_16840	COG0114	fumarate hydratase activity
N7985_16850	COG0697	spore germination
N7985_16855	COG0814	amino acid
N7985_16865	COG2197	response regulator
N7985_16870	COG4585	Histidine kinase
N7985_16875	COG4758	membrane
N7985_16880	COG3595	metallopeptidase activity
N7985_16885	COG1842	Phage shock protein A
N7985_16890	COG4758	membrane
N7985_16895	COG2814	Major facilitator Superfamily
N7985_16900	COG2096	Adenosyltransferase
N7985_16905	COG1120	ATPase activity
N7985_16910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7985_16915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7985_16920	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_16925	COG3386	PFAM SMP-30 Gluconolaconase
N7985_16930	COG2205	protein histidine kinase activity
N7985_16935	COG0745	RESPONSE REGULATOR receiver
N7985_16945	COG1191	sigma factor activity
N7985_16955	COG2140	Oxalate decarboxylase
N7985_16965	COG0577	efflux transmembrane transporter activity
N7985_16970	COG1136	(ABC) transporter
N7985_16975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7985_16980	COG1120	ATPase activity
N7985_16985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7985_16990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7985_16995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7985_17000	COG0531	amino acid
N7985_17010	COG1988	membrane-bound metal-dependent
N7985_17015	COG1368	sulfuric ester hydrolase activity
N7985_17020	COG1910	domain protein
N7985_17025	COG0725	ABC transporter, periplasmic molybdate-binding protein
N7985_17030	COG4149	molybdate abc transporter
N7985_17035	COG0656	L-ascorbic acid biosynthetic process
N7985_17045	COG0025	NhaP-type Na H and K H
N7985_17050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7985_17055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N7985_17060	COG3973	AAA domain
N7985_17070	COG2860	membrane
N7985_17075	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
N7985_17080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N7985_17085	COG2217	Heavy metal translocating P-type atpase
N7985_17090	COG2217	Heavy metal translocating P-type atpase
N7985_17095	COG2608	mercury ion transmembrane transporter activity
N7985_17100	COG1937	Protein conserved in bacteria
N7985_17105	COG0673	inositol 2-dehydrogenase activity
N7985_17110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7985_17115	COG1289	transmembrane transporter activity
N7985_17125	COG2076	Multidrug Resistance protein
N7985_17130	COG1309	transcriptional regulator
N7985_17135	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_17160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N7985_17165	COG0557	exoribonuclease II activity
N7985_17170	COG1647	Serine aminopeptidase, S33
N7985_17175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N7985_17180	COG0596	Alpha beta hydrolase
N7985_17185	COG1476	TRANSCRIPTIONal
N7985_17190	COG1396	sequence-specific DNA binding
N7985_17195	COG1396	sequence-specific DNA binding
N7985_17200	COG1733	regulation of RNA biosynthetic process
N7985_17205	COG0840	transmembrane signaling receptor activity
N7985_17230	COG1131	(ABC) transporter
N7985_17260	COG1174	glycine betaine transport
N7985_17265	COG1732	Glycine betaine
N7985_17270	COG1174	glycine betaine transport
N7985_17275	COG1125	glycine betaine transport
N7985_17275	COG0517	IMP dehydrogenase activity
N7985_17280	COG1510	regulation of RNA biosynthetic process
N7985_17285	COG1174	glycine betaine transport
N7985_17290	COG1732	Glycine betaine
N7985_17295	COG1174	glycine betaine transport
N7985_17300	COG1125	glycine betaine transport
N7985_17300	COG0517	IMP dehydrogenase activity
N7985_17305	COG1510	regulation of RNA biosynthetic process
N7985_17310	COG2095	MarC family integral membrane protein
N7985_17320	COG3064	Membrane
N7985_17325	COG4640	response to antibiotic
N7985_17330	COG0456	acetyltransferase
N7985_17335	COG0148	phosphopyruvate hydratase activity
N7985_17340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N7985_17345	COG0149	triose-phosphate isomerase activity
N7985_17350	COG0126	phosphoglycerate kinase activity
N7985_17355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N7985_17360	COG2390	Transcriptional regulator
N7985_17365	COG2814	Major facilitator Superfamily
N7985_17370	COG1609	Transcriptional regulator
N7985_17375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7985_17380	COG0583	DNA-binding transcription factor activity
N7985_17385	COG0697	spore germination
N7985_17390	COG1113	amino acid transport
N7985_17395	COG3858	chitin binding
N7985_17400	COG1556	Lactate utilization protein
N7985_17405	COG1139	Iron-sulfur cluster binding protein
N7985_17410	COG0247	lactate metabolic process
N7985_17415	COG2197	response regulator
N7985_17420	COG4585	Histidine kinase
N7985_17425	COG0842	Transport permease protein
N7985_17430	COG1131	(ABC) transporter
N7985_17435	COG0596	Alpha beta hydrolase
N7985_17440	COG2208	phosphoserine phosphatase activity
N7985_17445	COG3867	Arabinogalactan endo-beta-1,4-galactanase
N7985_17450	COG1874	Beta-galactosidase
N7985_17455	COG3833	ABC-type maltose transport systems, permease component
N7985_17460	COG1175	transmembrane transport
N7985_17465	COG2182	Extracellular solute-binding protein
N7985_17470	COG1609	Transcriptional regulator
N7985_17475	COG2186	Transcriptional regulator
N7985_17480	COG1620	l-lactate permease
N7985_17485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N7985_17490	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N7985_17500	COG5039	Polysaccharide pyruvyl transferase
N7985_17505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N7985_17510	COG0110	maltose O-acetyltransferase activity
N7985_17515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N7985_17520	COG2244	polysaccharide biosynthetic process
N7985_17525	COG1216	Glycosyl transferase, family 2
N7985_17530	COG5039	Polysaccharide pyruvyl transferase
N7985_17535	COG1216	Glycosyl transferase, family 2
N7985_17545	COG0438	transferase activity, transferring glycosyl groups
N7985_17550	COG1215	transferase activity, transferring glycosyl groups
N7985_17555	COG0438	transferase activity, transferring glycosyl groups
N7985_17560	COG1086	Polysaccharide biosynthesis protein
N7985_17565	COG0489	protein tyrosine kinase activity
N7985_17575	COG1396	sequence-specific DNA binding
N7985_17580	COG2272	Belongs to the type-B carboxylesterase lipase family
N7985_17590	COG3479	Phenolic acid decarboxylase
N7985_17600	COG1794	racemase activity, acting on amino acids and derivatives
N7985_17605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7985_17610	COG1621	beta-fructofuranosidase activity
N7985_17615	COG1621	beta-fructofuranosidase activity
N7985_17620	COG0531	amino acid
N7985_17625	COG1309	transcriptional regulator
N7985_17630	COG2076	Multidrug Resistance protein
N7985_17635	COG2076	Multidrug Resistance protein
N7985_17650	COG0740	serine-type endopeptidase activity
N7985_17655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7985_17660	COG0366	Alpha amylase catalytic
N7985_17665	COG1554	hydrolase, family 65, central catalytic
N7985_17670	COG5521	maltodextrose utilization protein MalA
N7985_17675	COG3833	ABC-type maltose transport systems, permease component
N7985_17680	COG1175	transmembrane transport
N7985_17685	COG2182	Extracellular solute-binding protein
N7985_17690	COG0366	Alpha amylase catalytic
N7985_17695	COG1609	Transcriptional regulator
N7985_17700	COG1611	Belongs to the LOG family
N7985_17705	COG1694	Mazg nucleotide pyrophosphohydrolase
N7985_17710	COG0659	secondary active sulfate transmembrane transporter activity
N7985_17715	COG0288	reversible hydration of carbon dioxide
N7985_17720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7985_17725	COG0577	efflux transmembrane transporter activity
N7985_17730	COG1136	(ABC) transporter
N7985_17735	COG5002	protein histidine kinase activity
N7985_17740	COG0745	RESPONSE REGULATOR receiver
N7985_17755	COG2162	N-hydroxyarylamine O-acetyltransferase activity
N7985_17760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7985_17765	COG1481	regulation of sporulation
N7985_17770	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N7985_17775	COG1660	Displays ATPase and GTPase activities
N7985_17780	COG1051	belongs to the nudix hydrolase family
N7985_17785	COG0492	ferredoxin-NADP+ reductase activity
N7985_17790	COG3883	PFAM NLP P60 protein
N7985_17790	COG0791	NLP P60 protein
N7985_17795	COG0457	Tetratricopeptide repeat
N7985_17800	COG1132	(ABC) transporter
N7985_17820	COG0140	phosphoribosyl-ATP diphosphatase activity
N7985_17820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N7985_17825	COG0107	imidazoleglycerol-phosphate synthase activity
N7985_17830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N7985_17835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N7985_17840	COG0131	Imidazoleglycerol-phosphate dehydratase
N7985_17845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N7985_17850	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N7985_17855	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
N7985_17860	COG4990	cell redox homeostasis
N7985_17865	COG5297	Belongs to the glycosyl hydrolase family 6
N7985_17870	COG0110	maltose O-acetyltransferase activity
N7985_17875	COG0546	phosphoglycolate phosphatase activity
N7985_17880	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
N7985_17885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N7985_17890	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
N7985_17895	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N7985_17900	COG0363	glucosamine-6-phosphate deaminase activity
N7985_17905	COG2188	Transcriptional regulator
N7985_17910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N7985_17915	COG1846	Transcriptional regulator
N7985_17930	COG1846	Transcriptional regulator
N7985_17935	COG2814	Major facilitator Superfamily
N7985_17940	COG1950	PFAM Membrane protein of
N7985_17945	COG1983	PspC domain protein
N7985_17950	COG3595	metallopeptidase activity
N7985_17970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N7985_17975	COG0556	nucleotide-excision repair
N7985_17980	COG4897	Protein conserved in bacteria
N7985_17985	COG3848	Pyruvate phosphate dikinase
N7985_17985	COG0574	Belongs to the PEP-utilizing enzyme family
N7985_17990	COG1309	transcriptional regulator
N7985_17995	COG2814	Major facilitator Superfamily
N7985_18000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7985_18010	COG0793	Belongs to the peptidase S41A family
N7985_18010	COG3409	Peptidoglycan-binding domain 1 protein
N7985_18015	COG2177	Part of the ABC transporter FtsEX involved in
N7985_18020	COG2884	Cell division ATP-binding protein ftsE
N7985_18025	COG2010	Cytochrome c
N7985_18030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7985_18040	COG0653	protein targeting
N7985_18045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N7985_18060	COG1516	flagellar protein fliS
N7985_18065	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N7985_18070	COG1334	flagellar protein FlaG
N7985_18075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7985_18080	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N7985_18085	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
N7985_18095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7985_18100	COG4786	Flagellar basal body rod
N7985_18100	COG1256	bacterial-type flagellum assembly
N7985_18105	COG3418	PFAM FlgN family protein
N7985_18110	COG2747	anti-sigma28 factor FlgM
N7985_18120	COG1040	competence protein
N7985_18130	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
N7985_18135	COG1307	EDD domain protein, DegV family
N7985_18140	COG2197	response regulator
N7985_18145	COG4585	Histidine kinase
N7985_18150	COG1739	Uncharacterized protein family UPF0029
N7985_18155	COG1316	TRANSCRIPTIONal
N7985_18160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N7985_18165	COG0438	transferase activity, transferring glycosyl groups
N7985_18170	COG1215	transferase activity, transferring glycosyl groups
N7985_18175	COG3206	protein involved in exopolysaccharide biosynthesis
N7985_18180	COG3307	-O-antigen
N7985_18185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N7985_18190	COG0438	transferase activity, transferring glycosyl groups
N7985_18190	COG0297	glycogen (starch) synthase activity
N7985_18195	COG2244	polysaccharide biosynthetic process
N7985_18210	COG2247	cell wall binding repeat
N7985_18210	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7985_18215	COG2247	cell wall binding repeat
N7985_18215	COG2385	sporulation resulting in formation of a cellular spore
N7985_18225	COG1316	TRANSCRIPTIONal
N7985_18230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N7985_18250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7985_18255	COG1134	teichoic acid transport
N7985_18260	COG1682	transport, permease protein
N7985_18265	COG1215	transferase activity, transferring glycosyl groups
N7985_18265	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7985_18270	COG0463	Glycosyl transferase, family 2
N7985_18315	COG4193	domain, Protein
N7985_18320	COG1482	cell wall glycoprotein biosynthetic process
N7985_18325	COG0697	spore germination
N7985_18330	COG0814	amino acid
N7985_18340	COG2814	Major facilitator Superfamily
N7985_18345	COG1316	TRANSCRIPTIONal
N7985_18350	COG0561	phosphatase activity
N7985_18355	COG0791	NLP P60 protein
N7985_18365	COG2843	Capsule synthesis protein
N7985_18375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N7985_18380	COG1609	Transcriptional regulator
N7985_18385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7985_18390	COG1869	D-ribose catabolic process
N7985_18395	COG1129	ABC transporter
N7985_18400	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7985_18405	COG1879	ABC-type sugar transport system periplasmic component
N7985_18410	COG3103	Sh3 type 3 domain protein
N7985_18420	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7985_18425	COG3527	Alpha-acetolactate decarboxylase
N7985_18430	COG0028	Belongs to the TPP enzyme family
N7985_18435	COG0583	DNA-binding transcription factor activity
N7985_18440	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N7985_18455	COG5337	Spore coat protein CotH
N7985_18465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7985_18475	COG0405	Gamma-glutamyltransferase
N7985_18480	COG1522	sequence-specific DNA binding
N7985_18485	COG2059	Chromate
N7985_18490	COG2059	Chromate
N7985_18505	COG5444	nuclease activity
N7985_18525	COG3878	Protein conserved in bacteria
N7985_18530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N7985_18535	COG4464	protein tyrosine phosphatase activity
N7985_18540	COG0489	protein tyrosine kinase activity
N7985_18545	COG3944	biosynthesis protein
N7985_18555	COG4715	Zinc finger, swim domain protein
N7985_18560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N7985_18565	COG0561	phosphatase activity
N7985_18570	COG1349	DNA-binding transcription factor activity
N7985_18575	COG0629	single-stranded DNA binding
N7985_18590	COG3764	Sortase (surface protein transpeptidase)
N7985_18600	COG3279	Response regulator of the LytR AlgR family
N7985_18610	COG2972	Histidine kinase
N7985_18610	COG0745	RESPONSE REGULATOR receiver
N7985_18615	COG1970	mechanosensitive ion channel activity
N7985_18620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N7985_18625	COG0457	Tetratricopeptide repeat
N7985_18630	COG4786	Flagellar basal body rod
N7985_18635	COG4786	Flagellar basal body rod
N7985_18640	COG1077	Cell shape determining protein MreB Mrl
N7985_18645	COG1609	Transcriptional regulator
N7985_18655	COG1846	Transcriptional regulator
N7985_18660	COG2814	Major facilitator Superfamily
N7985_18665	COG3420	alginic acid biosynthetic process
N7985_18670	COG1953	Uracil, thiamine, allantoin
N7985_18675	COG0477	Major facilitator Superfamily
N7985_18680	COG1335	isochorismatase
N7985_18690	COG0004	ammonium transporteR
N7985_18695	COG0347	Belongs to the P(II) protein family
N7985_18700	COG0671	phosphoesterase, PA-phosphatase related
N7985_18710	COG0739	heme binding
N7985_18715	COG1247	-acetyltransferase
N7985_18735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7985_18740	COG0789	Transcriptional regulator
N7985_18750	COG2910	NAD(P)H-binding
N7985_18755	COG1959	2 iron, 2 sulfur cluster binding
N7985_18760	COG0804	urea catabolic process
N7985_18765	COG0832	Belongs to the urease beta subunit family
N7985_18770	COG0831	urea catabolic process
N7985_18785	COG3237	CsbD-like
N7985_18790	COG1994	Peptidase M50
N7985_18795	COG0457	Tetratricopeptide repeat
N7985_18800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N7985_18805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N7985_18815	COG2304	oxidoreductase activity
N7985_18825	COG2304	oxidoreductase activity
N7985_18830	COG2385	sporulation resulting in formation of a cellular spore
N7985_18835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N7985_18845	COG4836	Membrane
N7985_18855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N7985_18860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N7985_18865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N7985_18870	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N7985_18875	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N7985_18880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N7985_18890	COG0356	it plays a direct role in the translocation of protons across the membrane
N7985_18900	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N7985_18905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N7985_18910	COG4475	Protein of unknown function (DUF436)
N7985_18915	COG0698	ribose 5-phosphate isomerase
N7985_18920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7985_18925	COG1971	Probably functions as a manganese efflux pump
N7985_18930	COG0009	L-threonylcarbamoyladenylate synthase
N7985_18935	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N7985_18955	COG2890	protein-(glutamine-N5) methyltransferase activity
N7985_18960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N7985_18965	COG0346	lactoylglutathione lyase activity
N7985_18970	COG0789	Transcriptional regulator
N7985_18975	COG0679	Auxin Efflux Carrier
N7985_18980	COG0281	malic enzyme
N7985_18985	COG1435	thymidine kinase activity
N7985_18995	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N7985_19005	COG1494	fructose-1,6-bisphosphatase
N7985_19010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N7985_19015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N7985_19020	COG0191	fructose-bisphosphate aldolase activity
N7985_19025	COG2204	response regulator
N7985_19030	COG4821	SIS domain
N7985_19035	COG0504	CTP synthase activity
N7985_19040	COG3343	RNA polymerase activity
N7985_19045	COG1960	acyl-CoA dehydrogenase activity
N7985_19050	COG2181	nitrate reductase activity
N7985_19050	COG0247	lactate metabolic process
N7985_19055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7985_19060	COG4294	response to UV
N7985_19070	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7985_19075	COG1132	(ABC) transporter
N7985_19080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7985_19090	COG2181	nitrate reductase activity
N7985_19095	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
N7985_19100	COG1140	nitrate reductase beta subunit
N7985_19105	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
N7985_19110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7985_19120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7985_19125	COG2223	nitrite transmembrane transporter activity
N7985_19130	COG0018	arginyl-trna synthetase
N7985_19135	COG4506	Protein conserved in bacteria
N7985_19150	COG0535	radical SAM domain protein
N7985_19160	COG1131	(ABC) transporter
N7985_19165	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N7985_19170	COG0612	Peptidase, M16
N7985_19175	COG0612	Peptidase, M16
N7985_19185	COG3391	amine dehydrogenase activity
N7985_19190	COG3391	amine dehydrogenase activity
N7985_19195	COG0457	Tetratricopeptide repeat
N7985_19225	COG1131	(ABC) transporter
N7985_19235	COG0010	Belongs to the arginase family
N7985_19240	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N7985_19245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7985_19260	COG1994	Peptidase M50
N7985_19265	COG1942	4-Oxalocrotonate Tautomerase
N7985_19270	COG1846	Transcriptional regulator
N7985_19275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N7985_19280	COG0477	Major facilitator Superfamily
N7985_19285	COG1959	2 iron, 2 sulfur cluster binding
N7985_19290	COG3465	dGTPase activity
N7985_19295	COG1078	dGTPase activity
N7985_19300	COG4844	belongs to the
N7985_19310	COG0697	spore germination
N7985_19315	COG0095	Lipoate-protein ligase
N7985_19320	COG0583	DNA-binding transcription factor activity
N7985_19325	COG0280	phosphate acetyltransferase
N7985_19330	COG3253	May function as heme-dependent peroxidase
N7985_19335	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_19340	COG0436	Aminotransferase
N7985_19345	COG2814	Major facilitator Superfamily
N7985_19350	COG0151	Belongs to the GarS family
N7985_19355	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_19360	COG1917	Cupin 2, conserved barrel domain protein
N7985_19365	COG0077	Prephenate dehydratase
N7985_19370	COG2814	Major facilitator Superfamily
N7985_19375	COG0833	amino acid
N7985_19380	COG4187	Peptidase family M20/M25/M40
N7985_19385	COG1012	belongs to the aldehyde dehydrogenase family
N7985_19390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7985_19400	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N7985_19405	COG1091	dTDP-4-dehydrorhamnose reductase activity
N7985_19410	COG1088	dTDP-glucose 4,6-dehydratase activity
N7985_19415	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
N7985_19420	COG3980	spore coat polysaccharide biosynthesis protein
N7985_19425	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
N7985_19430	COG2089	acid synthase
N7985_19435	COG0456	acetyltransferase
N7985_19440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N7985_19445	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7985_19450	COG0463	Glycosyl transferase, family 2
N7985_19460	COG2363	Small membrane protein
N7985_19465	COG2233	PERMEase
N7985_19475	COG1012	belongs to the aldehyde dehydrogenase family
N7985_19480	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N7985_19485	COG1216	Glycosyl transferase, family 2
N7985_19500	COG1695	Transcriptional regulator
N7985_19505	COG0351	phosphomethylpyrimidine kinase
N7985_19515	COG1621	beta-fructofuranosidase activity
N7985_19520	COG1263	PTS System
N7985_19520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_19525	COG2116	formate transmembrane transporter activity
N7985_19530	COG3711	transcriptional antiterminator
N7985_19540	COG1404	Belongs to the peptidase S8 family
N7985_19545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7985_19550	COG0778	Nitroreductase
N7985_19555	COG0772	Belongs to the SEDS family
N7985_19565	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N7985_19570	COG1845	cytochrome c oxidase, subunit III
N7985_19575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7985_19580	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7985_19585	COG2261	transglycosylase associated protein
N7985_19590	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
N7985_19595	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
N7985_19600	COG2246	polysaccharide biosynthetic process
N7985_19605	COG1309	transcriptional regulator
N7985_19615	COG3162	membrane
N7985_19620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7985_19625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N7985_19630	COG2837	iron assimilation
N7985_19635	COG2822	iron ion transport
N7985_19640	COG0672	)-iron permease
N7985_19645	COG0352	thiamine-phosphate diphosphorylase activity
N7985_19650	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
N7985_19655	COG0583	DNA-binding transcription factor activity
N7985_19660	COG1380	Effector of murein hydrolase LrgA
N7985_19665	COG1346	cytolysis
N7985_19670	COG2814	Major facilitator Superfamily
N7985_19675	COG4895	conserved protein (DUF2196)
N7985_19680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N7985_19685	COG0346	lactoylglutathione lyase activity
N7985_19710	COG1404	Belongs to the peptidase S8 family
N7985_19715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_19715	COG1263	PTS System
N7985_19720	COG3711	transcriptional antiterminator
N7985_19725	COG1442	glycosyl transferase family 8
N7985_19730	COG5522	Integral membrane protein (intg_mem_TP0381)
N7985_19735	COG1846	Transcriptional regulator
N7985_19740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N7985_19745	COG2234	aminopeptidase activity
N7985_19760	COG2814	Major facilitator Superfamily
N7985_19765	COG2357	RelA SpoT domain protein
N7985_19770	COG1575	Belongs to the MenA family. Type 1 subfamily
N7985_19785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7985_19790	COG1696	Membrane protein involved in D-alanine export
N7985_19795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7985_19800	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
N7985_19805	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
N7985_19810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7985_19815	COG1486	melibiose metabolic process
N7985_19820	COG1447	Phosphotransferase system cellobiose-specific component IIA
N7985_19825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7985_19830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7985_19835	COG3711	transcriptional antiterminator
N7985_19835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7985_19845	COG2094	Belongs to the DNA glycosylase MPG family
N7985_19850	COG0753	catalase activity
N7985_19855	COG2814	Major facilitator Superfamily
N7985_19860	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N7985_19865	COG1131	(ABC) transporter
N7985_19885	COG1595	DNA-templated transcription, initiation
N7985_19890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N7985_19895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N7985_19900	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N7985_19905	COG4988	ABC transporter
N7985_19910	COG1294	oxidase, subunit
N7985_19915	COG1271	oxidase subunit
N7985_19920	COG3493	citrate carrier protein
N7985_19925	COG0501	Belongs to the peptidase M48B family
N7985_19935	COG0726	polysaccharide deacetylase
N7985_19950	COG3842	ATPase activity
N7985_19955	COG2508	Transcriptional regulator
N7985_19960	COG1012	belongs to the aldehyde dehydrogenase family
N7985_19965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7985_19975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N7985_19980	COG1881	PFAM PEBP family protein
N7985_19985	COG0583	DNA-binding transcription factor activity
N7985_19995	COG4585	Histidine kinase
N7985_20000	COG2197	response regulator
N7985_20005	COG2195	Cleaves the N-terminal amino acid of tripeptides
N7985_20020	COG4894	glucomannan catabolic process
N7985_20025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N7985_20030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N7985_20035	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_20040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7985_20045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N7985_20050	COG2610	gluconate transmembrane transporter activity
N7985_20055	COG0500	methyltransferase
N7985_20060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N7985_20075	COG0753	catalase activity
N7985_20075	COG0693	protein deglycase activity
N7985_20080	COG2851	Citrate transporter
N7985_20085	COG2273	Hydrolase Family 16
N7985_20090	COG3711	transcriptional antiterminator
N7985_20100	COG2270	Major facilitator Superfamily
N7985_20105	COG0513	Belongs to the DEAD box helicase family
N7985_20110	COG2755	lipolytic protein G-D-S-L family
N7985_20110	COG3401	FG-GAP repeat protein
N7985_20155	COG3209	COG3209 Rhs family protein
N7985_20160	COG0697	spore germination
N7985_20165	COG0589	response to stress
N7985_20170	COG2723	6-phospho-beta-galactosidase activity
N7985_20175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_20175	COG2190	(PTS) system
N7985_20175	COG1263	PTS System
N7985_20220	COG3507	Belongs to the glycosyl hydrolase 43 family
N7985_20235	COG2986	histidine ammonia-lyase
N7985_20240	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N7985_20245	COG1228	amidohydrolase
N7985_20250	COG0010	Belongs to the arginase family
N7985_20255	COG0833	amino acid
N7985_20260	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N7985_20265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N7985_20270	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N7985_20275	COG2390	Transcriptional regulator
N7985_20285	COG3192	ethanolamine utilization protein
N7985_20290	COG2079	MmgE PrpD family protein
N7985_20295	COG1473	amidohydrolase
N7985_20300	COG1126	abc transporter atp-binding protein
N7985_20305	COG0765	amino acid transport
N7985_20310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7985_20315	COG0456	acetyltransferase
N7985_20320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7985_20325	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
N7985_20330	COG0561	phosphatase activity
N7985_20360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7985_20365	COG5294	Protein conserved in bacteria
N7985_20370	COG0577	efflux transmembrane transporter activity
N7985_20375	COG1136	(ABC) transporter
N7985_20380	COG2205	protein histidine kinase activity
N7985_20385	COG0745	RESPONSE REGULATOR receiver
N7985_20390	COG0191	fructose-bisphosphate aldolase activity
N7985_20395	COG1082	Xylose isomerase domain protein TIM barrel
N7985_20400	COG1082	Xylose isomerase domain protein TIM barrel
N7985_20405	COG0673	inositol 2-dehydrogenase activity
N7985_20410	COG2814	Major facilitator Superfamily
N7985_20415	COG1082	Xylose isomerase domain protein TIM barrel
N7985_20420	COG3962	Belongs to the TPP enzyme family
N7985_20425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7985_20435	COG1012	belongs to the aldehyde dehydrogenase family
N7985_20440	COG1349	DNA-binding transcription factor activity
N7985_20445	COG0667	Aldo Keto reductase
N7985_20460	COG2814	Major facilitator Superfamily
N7985_20465	COG0326	Molecular chaperone. Has ATPase activity
N7985_20475	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_20500	COG1309	transcriptional regulator
N7985_20505	COG1012	belongs to the aldehyde dehydrogenase family
N7985_20510	COG1714	RDD family
N7985_20515	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N7985_20525	COG1714	RDD family
N7985_20530	COG2311	Membrane
N7985_20535	COG1917	Cupin 2, conserved barrel domain protein
N7985_20540	COG1309	transcriptional regulator
N7985_20545	COG1028	Short-chain dehydrogenase reductase Sdr
N7985_20550	COG1846	Transcriptional regulator
N7985_20555	COG1380	Effector of murein hydrolase LrgA
N7985_20560	COG1346	cytolysis
N7985_20565	COG5039	Polysaccharide pyruvyl transferase
N7985_20570	COG1929	Belongs to the glycerate kinase type-1 family
N7985_20575	COG1802	Transcriptional regulator
N7985_20580	COG1070	Carbohydrate kinase
N7985_20585	COG2610	gluconate transmembrane transporter activity
N7985_20590	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N7985_20595	COG0450	alkyl hydroperoxide reductase
N7985_20600	COG3634	alkyl hydroperoxide reductase activity
N7985_20620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7985_20620	COG1263	PTS System
N7985_20625	COG2188	Transcriptional regulator
N7985_20640	COG1131	(ABC) transporter
N7985_20645	COG1994	Peptidase M50
N7985_20650	COG0535	radical SAM domain protein
N7985_20660	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
N7985_20670	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N7985_20685	COG1063	alcohol dehydrogenase
N7985_20705	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
N7985_20710	COG0456	acetyltransferase
N7985_20715	COG0457	Tetratricopeptide repeat
N7985_20725	COG0010	Belongs to the arginase family
N7985_20730	COG0833	amino acid
N7985_20735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N7985_20740	COG3829	transcription factor binding
N7985_20755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7985_20760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N7985_20765	COG4853	Protein conserved in bacteria
N7985_20770	COG4863	YycH protein
N7985_20775	COG5002	protein histidine kinase activity
N7985_20780	COG0745	RESPONSE REGULATOR receiver
N7985_20810	COG0346	lactoylglutathione lyase activity
N7985_20815	COG0305	Participates in initiation and elongation during chromosome replication
N7985_20830	COG3093	addiction module antidote protein HigA
N7985_20835	COG2807	transmembrane transport
N7985_20840	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N7985_20845	COG0359	binds to the 23S rRNA
N7985_20850	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
N7985_20855	COG4241	membrane
N7985_20865	COG5577	PFAM Coat F domain
N7985_20870	COG1733	regulation of RNA biosynthetic process
N7985_20875	COG1227	inorganic diphosphatase activity
N7985_20890	COG2271	Major facilitator Superfamily
N7985_20895	COG0789	Transcriptional regulator
N7985_20895	COG4978	Transcriptional regulator
N7985_20915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7985_20920	COG1846	Transcriptional regulator
N7985_20925	COG2153	protein acetylation
N7985_20930	COG2364	Membrane
N7985_20935	COG0456	acetyltransferase
N7985_20940	COG2315	Protein conserved in bacteria
N7985_20945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7985_20965	COG0789	Transcriptional regulator
N7985_20970	COG0697	spore germination
N7985_20975	COG1331	Highly conserved protein containing a thioredoxin domain
N7985_20980	COG1266	CAAX protease self-immunity
N7985_20985	COG0477	Major facilitator Superfamily
N7985_20985	COG2814	Major facilitator Superfamily
N7985_20990	COG0110	maltose O-acetyltransferase activity
N7985_20995	COG0346	lactoylglutathione lyase activity
N7985_21000	COG1609	Transcriptional regulator
N7985_21005	COG0708	Exodeoxyribonuclease III
N7985_21010	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N7985_21015	COG0629	single-stranded DNA binding
N7985_21020	COG0360	Binds together with S18 to 16S ribosomal RNA
N7985_21025	COG0012	GTP binding
N7985_21030	COG0243	molybdopterin cofactor binding
N7985_21035	COG4481	Protein conserved in bacteria
N7985_21040	COG3949	Membrane
N7985_21050	COG1475	DNA binding
N7985_21055	COG1192	Involved in chromosome partitioning
N7985_21065	COG1475	DNA binding
N7985_21070	COG0357	Ribosomal RNA small subunit methyltransferase G
N7985_21075	COG0445	tRNA wobble uridine modification
N7985_21080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N7985_21085	COG1847	R3H domain protein
N7985_21090	COG0706	membrane insertase activity
N7985_21095	COG0594	ribonuclease P activity
N7985_21115	COG1388	LysM domain
N7985_21115	COG3584	3D domain protein
N7985_21125	COG0582	viral genome integration into host DNA
N7985_21195	COG2887	Belongs to the helicase family. UvrD subfamily
N7985_21200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7985_21205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7985_21210	COG0716	FMN binding
N7985_21250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N7985_21290	COG0328	RNA-DNA hybrid ribonuclease activity
N7985_21310	COG0587	DNA-directed DNA polymerase activity
N7985_21335	COG0194	GDP metabolic process
N7985_21385	COG0187	DNA topoisomerase II activity
N7985_21390	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7985_21440	COG5444	nuclease activity
N7985_21495	COG5280	Phage tail tape measure protein TP901
N7985_21495	COG3953	SLT domain
N7985_21585	COG0457	Tetratricopeptide repeat