locus-tag	class	description
N7980_00015	COG0594	ribonuclease P activity
N7980_00020	COG0706	membrane insertase activity
N7980_00025	COG1847	R3H domain protein
N7980_00030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N7980_00035	COG0445	tRNA wobble uridine modification
N7980_00040	COG0357	Ribosomal RNA small subunit methyltransferase G
N7980_00045	COG1475	DNA binding
N7980_00055	COG1192	Involved in chromosome partitioning
N7980_00060	COG1475	DNA binding
N7980_00070	COG3949	Membrane
N7980_00075	COG4481	Protein conserved in bacteria
N7980_00080	COG0243	molybdopterin cofactor binding
N7980_00085	COG0012	GTP binding
N7980_00090	COG0360	Binds together with S18 to 16S ribosomal RNA
N7980_00095	COG0629	single-stranded DNA binding
N7980_00100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N7980_00105	COG0708	Exodeoxyribonuclease III
N7980_00110	COG1609	Transcriptional regulator
N7980_00115	COG0346	lactoylglutathione lyase activity
N7980_00120	COG0110	maltose O-acetyltransferase activity
N7980_00125	COG0477	Major facilitator Superfamily
N7980_00125	COG2814	Major facilitator Superfamily
N7980_00130	COG1266	CAAX protease self-immunity
N7980_00135	COG1331	Highly conserved protein containing a thioredoxin domain
N7980_00140	COG0697	spore germination
N7980_00145	COG0789	Transcriptional regulator
N7980_00165	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7980_00170	COG2315	Protein conserved in bacteria
N7980_00175	COG0456	acetyltransferase
N7980_00180	COG2364	Membrane
N7980_00185	COG2153	protein acetylation
N7980_00190	COG1846	Transcriptional regulator
N7980_00195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7980_00215	COG4978	Transcriptional regulator
N7980_00215	COG0789	Transcriptional regulator
N7980_00220	COG2271	Major facilitator Superfamily
N7980_00235	COG1227	inorganic diphosphatase activity
N7980_00240	COG1733	regulation of RNA biosynthetic process
N7980_00245	COG5577	PFAM Coat F domain
N7980_00255	COG4241	membrane
N7980_00260	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
N7980_00265	COG0359	binds to the 23S rRNA
N7980_00270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N7980_00275	COG2807	transmembrane transport
N7980_00280	COG3093	addiction module antidote protein HigA
N7980_00295	COG0305	Participates in initiation and elongation during chromosome replication
N7980_00300	COG0346	lactoylglutathione lyase activity
N7980_00330	COG0745	RESPONSE REGULATOR receiver
N7980_00335	COG5002	protein histidine kinase activity
N7980_00340	COG4863	YycH protein
N7980_00345	COG4853	Protein conserved in bacteria
N7980_00350	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N7980_00355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7980_00370	COG3829	transcription factor binding
N7980_00375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N7980_00380	COG0833	amino acid
N7980_00385	COG0010	Belongs to the arginase family
N7980_00395	COG0457	Tetratricopeptide repeat
N7980_00400	COG0456	acetyltransferase
N7980_00405	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
N7980_00425	COG1063	alcohol dehydrogenase
N7980_00440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N7980_00450	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
N7980_00460	COG0535	radical SAM domain protein
N7980_00465	COG1994	Peptidase M50
N7980_00470	COG1131	(ABC) transporter
N7980_00485	COG2188	Transcriptional regulator
N7980_00490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_00490	COG1263	PTS System
N7980_00510	COG3634	alkyl hydroperoxide reductase activity
N7980_00515	COG0450	alkyl hydroperoxide reductase
N7980_00520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N7980_00525	COG2610	gluconate transmembrane transporter activity
N7980_00530	COG1070	Carbohydrate kinase
N7980_00535	COG1802	Transcriptional regulator
N7980_00540	COG1929	Belongs to the glycerate kinase type-1 family
N7980_00545	COG5039	Polysaccharide pyruvyl transferase
N7980_00550	COG1346	cytolysis
N7980_00555	COG1380	Effector of murein hydrolase LrgA
N7980_00560	COG1846	Transcriptional regulator
N7980_00565	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_00570	COG1309	transcriptional regulator
N7980_00575	COG1917	Cupin 2, conserved barrel domain protein
N7980_00580	COG2311	Membrane
N7980_00585	COG1714	RDD family
N7980_00595	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N7980_00600	COG1714	RDD family
N7980_00605	COG1012	belongs to the aldehyde dehydrogenase family
N7980_00610	COG1309	transcriptional regulator
N7980_00635	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_00645	COG0326	Molecular chaperone. Has ATPase activity
N7980_00650	COG2814	Major facilitator Superfamily
N7980_00665	COG0667	Aldo Keto reductase
N7980_00670	COG1349	DNA-binding transcription factor activity
N7980_00675	COG1012	belongs to the aldehyde dehydrogenase family
N7980_00685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7980_00690	COG3962	Belongs to the TPP enzyme family
N7980_00695	COG1082	Xylose isomerase domain protein TIM barrel
N7980_00700	COG2814	Major facilitator Superfamily
N7980_00705	COG0673	inositol 2-dehydrogenase activity
N7980_00710	COG1082	Xylose isomerase domain protein TIM barrel
N7980_00715	COG1082	Xylose isomerase domain protein TIM barrel
N7980_00720	COG0191	fructose-bisphosphate aldolase activity
N7980_00725	COG0745	RESPONSE REGULATOR receiver
N7980_00730	COG2205	protein histidine kinase activity
N7980_00735	COG1136	(ABC) transporter
N7980_00740	COG0577	efflux transmembrane transporter activity
N7980_00745	COG5294	Protein conserved in bacteria
N7980_00750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7980_00780	COG0561	phosphatase activity
N7980_00785	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
N7980_00790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7980_00795	COG0456	acetyltransferase
N7980_00800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7980_00805	COG0765	amino acid transport
N7980_00810	COG1126	abc transporter atp-binding protein
N7980_00815	COG1473	amidohydrolase
N7980_00820	COG2079	MmgE PrpD family protein
N7980_00825	COG3192	ethanolamine utilization protein
N7980_00835	COG2390	Transcriptional regulator
N7980_00840	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N7980_00845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N7980_00850	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N7980_00855	COG0833	amino acid
N7980_00860	COG0010	Belongs to the arginase family
N7980_00865	COG1228	amidohydrolase
N7980_00870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N7980_00875	COG2986	histidine ammonia-lyase
N7980_00890	COG3507	Belongs to the glycosyl hydrolase 43 family
N7980_00935	COG1263	PTS System
N7980_00935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_00935	COG2190	(PTS) system
N7980_00940	COG2723	6-phospho-beta-galactosidase activity
N7980_00945	COG0589	response to stress
N7980_00950	COG0697	spore germination
N7980_00955	COG3209	COG3209 Rhs family protein
N7980_01000	COG2755	lipolytic protein G-D-S-L family
N7980_01000	COG3401	FG-GAP repeat protein
N7980_01005	COG0513	Belongs to the DEAD box helicase family
N7980_01010	COG2270	Major facilitator Superfamily
N7980_01020	COG3711	transcriptional antiterminator
N7980_01025	COG2273	Hydrolase Family 16
N7980_01030	COG2851	Citrate transporter
N7980_01035	COG0693	protein deglycase activity
N7980_01035	COG0753	catalase activity
N7980_01050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N7980_01055	COG0500	methyltransferase
N7980_01060	COG2610	gluconate transmembrane transporter activity
N7980_01065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N7980_01070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7980_01075	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_01080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N7980_01085	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N7980_01090	COG4894	glucomannan catabolic process
N7980_01105	COG2195	Cleaves the N-terminal amino acid of tripeptides
N7980_01110	COG2197	response regulator
N7980_01115	COG4585	Histidine kinase
N7980_01125	COG0583	DNA-binding transcription factor activity
N7980_01130	COG1881	PFAM PEBP family protein
N7980_01135	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N7980_01145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7980_01150	COG1012	belongs to the aldehyde dehydrogenase family
N7980_01155	COG2508	Transcriptional regulator
N7980_01160	COG3842	ATPase activity
N7980_01175	COG0726	polysaccharide deacetylase
N7980_01185	COG0501	Belongs to the peptidase M48B family
N7980_01190	COG3493	citrate carrier protein
N7980_01195	COG1271	oxidase subunit
N7980_01200	COG1294	oxidase, subunit
N7980_01205	COG4988	ABC transporter
N7980_01210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N7980_01215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N7980_01220	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N7980_01225	COG1595	DNA-templated transcription, initiation
N7980_01245	COG1131	(ABC) transporter
N7980_01250	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N7980_01255	COG2814	Major facilitator Superfamily
N7980_01260	COG0753	catalase activity
N7980_01265	COG2094	Belongs to the DNA glycosylase MPG family
N7980_01275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7980_01275	COG3711	transcriptional antiterminator
N7980_01280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7980_01285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7980_01290	COG1447	Phosphotransferase system cellobiose-specific component IIA
N7980_01295	COG1486	melibiose metabolic process
N7980_01300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7980_01305	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
N7980_01310	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
N7980_01315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7980_01320	COG1696	Membrane protein involved in D-alanine export
N7980_01325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_01340	COG1575	Belongs to the MenA family. Type 1 subfamily
N7980_01345	COG2357	RelA SpoT domain protein
N7980_01350	COG2814	Major facilitator Superfamily
N7980_01365	COG2234	aminopeptidase activity
N7980_01370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N7980_01375	COG1846	Transcriptional regulator
N7980_01380	COG5522	Integral membrane protein (intg_mem_TP0381)
N7980_01385	COG1442	glycosyl transferase family 8
N7980_01390	COG3711	transcriptional antiterminator
N7980_01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_01395	COG1263	PTS System
N7980_01400	COG1404	Belongs to the peptidase S8 family
N7980_01425	COG0346	lactoylglutathione lyase activity
N7980_01430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N7980_01435	COG4895	conserved protein (DUF2196)
N7980_01440	COG2814	Major facilitator Superfamily
N7980_01445	COG1346	cytolysis
N7980_01450	COG1380	Effector of murein hydrolase LrgA
N7980_01455	COG0583	DNA-binding transcription factor activity
N7980_01460	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
N7980_01465	COG0352	thiamine-phosphate diphosphorylase activity
N7980_01470	COG0672	)-iron permease
N7980_01475	COG2822	iron ion transport
N7980_01480	COG2837	iron assimilation
N7980_01485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N7980_01490	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7980_01495	COG3162	membrane
N7980_01510	COG2246	polysaccharide biosynthetic process
N7980_01515	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
N7980_01520	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
N7980_01525	COG2261	transglycosylase associated protein
N7980_01530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7980_01535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7980_01540	COG1845	cytochrome c oxidase, subunit III
N7980_01545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N7980_01555	COG0772	Belongs to the SEDS family
N7980_01560	COG0778	Nitroreductase
N7980_01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7980_01570	COG1404	Belongs to the peptidase S8 family
N7980_01580	COG3711	transcriptional antiterminator
N7980_01585	COG2116	formate transmembrane transporter activity
N7980_01590	COG1263	PTS System
N7980_01590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_01595	COG1621	beta-fructofuranosidase activity
N7980_01605	COG0351	phosphomethylpyrimidine kinase
N7980_01610	COG1695	Transcriptional regulator
N7980_01625	COG1216	Glycosyl transferase, family 2
N7980_01630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N7980_01635	COG1012	belongs to the aldehyde dehydrogenase family
N7980_01645	COG2233	PERMEase
N7980_01650	COG2363	Small membrane protein
N7980_01660	COG0463	Glycosyl transferase, family 2
N7980_01665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7980_01670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N7980_01675	COG0456	acetyltransferase
N7980_01680	COG2089	acid synthase
N7980_01685	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
N7980_01690	COG3980	spore coat polysaccharide biosynthesis protein
N7980_01695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
N7980_01700	COG1088	dTDP-glucose 4,6-dehydratase activity
N7980_01705	COG1091	dTDP-4-dehydrorhamnose reductase activity
N7980_01710	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N7980_01720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7980_01725	COG1012	belongs to the aldehyde dehydrogenase family
N7980_01730	COG4187	Peptidase family M20/M25/M40
N7980_01735	COG0833	amino acid
N7980_01740	COG2814	Major facilitator Superfamily
N7980_01745	COG0077	Prephenate dehydratase
N7980_01750	COG1917	Cupin 2, conserved barrel domain protein
N7980_01755	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_01760	COG0151	Belongs to the GarS family
N7980_01765	COG2814	Major facilitator Superfamily
N7980_01770	COG0436	Aminotransferase
N7980_01775	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_01780	COG3253	May function as heme-dependent peroxidase
N7980_01785	COG0280	phosphate acetyltransferase
N7980_01790	COG0583	DNA-binding transcription factor activity
N7980_01795	COG0095	Lipoate-protein ligase
N7980_01800	COG0697	spore germination
N7980_01810	COG4844	belongs to the
N7980_01815	COG1078	dGTPase activity
N7980_01820	COG3465	dGTPase activity
N7980_01825	COG1959	2 iron, 2 sulfur cluster binding
N7980_01830	COG0477	Major facilitator Superfamily
N7980_01835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N7980_01840	COG1846	Transcriptional regulator
N7980_01845	COG1942	4-Oxalocrotonate Tautomerase
N7980_01850	COG1994	Peptidase M50
N7980_01865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7980_01870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N7980_01875	COG0010	Belongs to the arginase family
N7980_01885	COG1131	(ABC) transporter
N7980_01915	COG0457	Tetratricopeptide repeat
N7980_01920	COG3391	amine dehydrogenase activity
N7980_01925	COG3391	amine dehydrogenase activity
N7980_01935	COG0612	Peptidase, M16
N7980_01940	COG0612	Peptidase, M16
N7980_01945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N7980_01950	COG1131	(ABC) transporter
N7980_01960	COG0535	radical SAM domain protein
N7980_01975	COG4506	Protein conserved in bacteria
N7980_01980	COG0018	arginyl-trna synthetase
N7980_01985	COG2223	nitrite transmembrane transporter activity
N7980_01990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7980_02000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7980_02005	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
N7980_02010	COG1140	nitrate reductase beta subunit
N7980_02015	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
N7980_02020	COG2181	nitrate reductase activity
N7980_02030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7980_02035	COG1132	(ABC) transporter
N7980_02040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7980_02050	COG4294	response to UV
N7980_02055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7980_02060	COG0247	lactate metabolic process
N7980_02060	COG2181	nitrate reductase activity
N7980_02065	COG1960	acyl-CoA dehydrogenase activity
N7980_02070	COG3343	RNA polymerase activity
N7980_02075	COG0504	CTP synthase activity
N7980_02080	COG4821	SIS domain
N7980_02085	COG2204	response regulator
N7980_02090	COG0191	fructose-bisphosphate aldolase activity
N7980_02095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N7980_02100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N7980_02105	COG1494	fructose-1,6-bisphosphatase
N7980_02115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N7980_02125	COG1435	thymidine kinase activity
N7980_02130	COG0281	malic enzyme
N7980_02135	COG0679	Auxin Efflux Carrier
N7980_02140	COG0789	Transcriptional regulator
N7980_02145	COG0346	lactoylglutathione lyase activity
N7980_02150	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N7980_02155	COG2890	protein-(glutamine-N5) methyltransferase activity
N7980_02175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N7980_02180	COG0009	L-threonylcarbamoyladenylate synthase
N7980_02185	COG1971	Probably functions as a manganese efflux pump
N7980_02190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7980_02195	COG0698	ribose 5-phosphate isomerase
N7980_02200	COG4475	Protein of unknown function (DUF436)
N7980_02205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N7980_02210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N7980_02220	COG0356	it plays a direct role in the translocation of protons across the membrane
N7980_02230	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N7980_02235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N7980_02240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N7980_02245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N7980_02250	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N7980_02255	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N7980_02265	COG4836	Membrane
N7980_02275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N7980_02280	COG2385	sporulation resulting in formation of a cellular spore
N7980_02285	COG2304	oxidoreductase activity
N7980_02295	COG2304	oxidoreductase activity
N7980_02305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N7980_02310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N7980_02315	COG0457	Tetratricopeptide repeat
N7980_02320	COG1994	Peptidase M50
N7980_02325	COG3237	CsbD-like
N7980_02340	COG0831	urea catabolic process
N7980_02345	COG0832	Belongs to the urease beta subunit family
N7980_02350	COG0804	urea catabolic process
N7980_02355	COG1959	2 iron, 2 sulfur cluster binding
N7980_02360	COG2910	NAD(P)H-binding
N7980_02370	COG0789	Transcriptional regulator
N7980_02375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7980_02395	COG1247	-acetyltransferase
N7980_02400	COG0739	heme binding
N7980_02410	COG0671	phosphoesterase, PA-phosphatase related
N7980_02415	COG0347	Belongs to the P(II) protein family
N7980_02420	COG0004	ammonium transporteR
N7980_02430	COG1335	isochorismatase
N7980_02435	COG0477	Major facilitator Superfamily
N7980_02440	COG1953	Uracil, thiamine, allantoin
N7980_02445	COG3420	alginic acid biosynthetic process
N7980_02450	COG2814	Major facilitator Superfamily
N7980_02455	COG1846	Transcriptional regulator
N7980_02465	COG1609	Transcriptional regulator
N7980_02470	COG1077	Cell shape determining protein MreB Mrl
N7980_02475	COG4786	Flagellar basal body rod
N7980_02480	COG4786	Flagellar basal body rod
N7980_02485	COG0457	Tetratricopeptide repeat
N7980_02490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N7980_02495	COG1970	mechanosensitive ion channel activity
N7980_02500	COG0745	RESPONSE REGULATOR receiver
N7980_02500	COG2972	Histidine kinase
N7980_02510	COG3279	Response regulator of the LytR AlgR family
N7980_02520	COG3764	Sortase (surface protein transpeptidase)
N7980_02535	COG0629	single-stranded DNA binding
N7980_02540	COG1349	DNA-binding transcription factor activity
N7980_02545	COG0561	phosphatase activity
N7980_02550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N7980_02555	COG4715	Zinc finger, swim domain protein
N7980_02565	COG3944	biosynthesis protein
N7980_02570	COG0489	protein tyrosine kinase activity
N7980_02575	COG4464	protein tyrosine phosphatase activity
N7980_02580	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N7980_02585	COG3878	Protein conserved in bacteria
N7980_02605	COG5444	nuclease activity
N7980_02620	COG2059	Chromate
N7980_02625	COG2059	Chromate
N7980_02630	COG1522	sequence-specific DNA binding
N7980_02635	COG0405	Gamma-glutamyltransferase
N7980_02645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7980_02655	COG5337	Spore coat protein CotH
N7980_02670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N7980_02675	COG0583	DNA-binding transcription factor activity
N7980_02680	COG0028	Belongs to the TPP enzyme family
N7980_02685	COG3527	Alpha-acetolactate decarboxylase
N7980_02690	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7980_02700	COG3103	Sh3 type 3 domain protein
N7980_02705	COG1879	ABC-type sugar transport system periplasmic component
N7980_02710	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7980_02715	COG1129	ABC transporter
N7980_02720	COG1869	D-ribose catabolic process
N7980_02725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7980_02730	COG1609	Transcriptional regulator
N7980_02735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N7980_02745	COG2843	Capsule synthesis protein
N7980_02755	COG0791	NLP P60 protein
N7980_02760	COG0561	phosphatase activity
N7980_02765	COG1316	TRANSCRIPTIONal
N7980_02770	COG2814	Major facilitator Superfamily
N7980_02780	COG0814	amino acid
N7980_02785	COG0697	spore germination
N7980_02790	COG1482	cell wall glycoprotein biosynthetic process
N7980_02795	COG4193	domain, Protein
N7980_02840	COG0463	Glycosyl transferase, family 2
N7980_02845	COG1215	transferase activity, transferring glycosyl groups
N7980_02845	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7980_02850	COG1682	transport, permease protein
N7980_02855	COG1134	teichoic acid transport
N7980_02860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7980_02880	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N7980_02885	COG1316	TRANSCRIPTIONal
N7980_02895	COG2385	sporulation resulting in formation of a cellular spore
N7980_02895	COG2247	cell wall binding repeat
N7980_02900	COG2247	cell wall binding repeat
N7980_02900	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7980_02915	COG2244	polysaccharide biosynthetic process
N7980_02920	COG0297	glycogen (starch) synthase activity
N7980_02920	COG0438	transferase activity, transferring glycosyl groups
N7980_02925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N7980_02930	COG3307	-O-antigen
N7980_02935	COG3206	protein involved in exopolysaccharide biosynthesis
N7980_02940	COG1215	transferase activity, transferring glycosyl groups
N7980_02945	COG0438	transferase activity, transferring glycosyl groups
N7980_02950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N7980_02955	COG1316	TRANSCRIPTIONal
N7980_02960	COG1739	Uncharacterized protein family UPF0029
N7980_02965	COG4585	Histidine kinase
N7980_02970	COG2197	response regulator
N7980_02975	COG1307	EDD domain protein, DegV family
N7980_02980	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
N7980_02990	COG1040	competence protein
N7980_03000	COG2747	anti-sigma28 factor FlgM
N7980_03005	COG3418	PFAM FlgN family protein
N7980_03010	COG4786	Flagellar basal body rod
N7980_03010	COG1256	bacterial-type flagellum assembly
N7980_03015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7980_03025	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
N7980_03030	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N7980_03035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7980_03040	COG1334	flagellar protein FlaG
N7980_03045	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N7980_03050	COG1516	flagellar protein fliS
N7980_03065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N7980_03070	COG0653	protein targeting
N7980_03080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7980_03085	COG2010	Cytochrome c
N7980_03090	COG2884	Cell division ATP-binding protein ftsE
N7980_03095	COG2177	Part of the ABC transporter FtsEX involved in
N7980_03100	COG0793	Belongs to the peptidase S41A family
N7980_03100	COG3409	Peptidoglycan-binding domain 1 protein
N7980_03110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7980_03115	COG2814	Major facilitator Superfamily
N7980_03120	COG1309	transcriptional regulator
N7980_03125	COG3848	Pyruvate phosphate dikinase
N7980_03125	COG0574	Belongs to the PEP-utilizing enzyme family
N7980_03130	COG4897	Protein conserved in bacteria
N7980_03135	COG0556	nucleotide-excision repair
N7980_03140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N7980_03160	COG3595	metallopeptidase activity
N7980_03165	COG1983	PspC domain protein
N7980_03170	COG1950	PFAM Membrane protein of
N7980_03175	COG2814	Major facilitator Superfamily
N7980_03180	COG1846	Transcriptional regulator
N7980_03195	COG1846	Transcriptional regulator
N7980_03200	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N7980_03205	COG2188	Transcriptional regulator
N7980_03210	COG0363	glucosamine-6-phosphate deaminase activity
N7980_03215	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N7980_03220	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
N7980_03225	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N7980_03230	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
N7980_03235	COG0546	phosphoglycolate phosphatase activity
N7980_03240	COG0110	maltose O-acetyltransferase activity
N7980_03245	COG5297	Belongs to the glycosyl hydrolase family 6
N7980_03250	COG4990	cell redox homeostasis
N7980_03255	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
N7980_03260	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N7980_03265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N7980_03270	COG0131	Imidazoleglycerol-phosphate dehydratase
N7980_03275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N7980_03280	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N7980_03285	COG0107	imidazoleglycerol-phosphate synthase activity
N7980_03290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N7980_03290	COG0140	phosphoribosyl-ATP diphosphatase activity
N7980_03310	COG1132	(ABC) transporter
N7980_03315	COG0457	Tetratricopeptide repeat
N7980_03320	COG3883	PFAM NLP P60 protein
N7980_03320	COG0791	NLP P60 protein
N7980_03325	COG0492	ferredoxin-NADP+ reductase activity
N7980_03330	COG1051	belongs to the nudix hydrolase family
N7980_03335	COG1660	Displays ATPase and GTPase activities
N7980_03340	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N7980_03345	COG1481	regulation of sporulation
N7980_03350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7980_03355	COG2162	N-hydroxyarylamine O-acetyltransferase activity
N7980_03370	COG0745	RESPONSE REGULATOR receiver
N7980_03375	COG5002	protein histidine kinase activity
N7980_03380	COG1136	(ABC) transporter
N7980_03385	COG0577	efflux transmembrane transporter activity
N7980_03390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7980_03395	COG0288	reversible hydration of carbon dioxide
N7980_03400	COG0659	secondary active sulfate transmembrane transporter activity
N7980_03405	COG1694	Mazg nucleotide pyrophosphohydrolase
N7980_03410	COG1611	Belongs to the LOG family
N7980_03415	COG1609	Transcriptional regulator
N7980_03420	COG0366	Alpha amylase catalytic
N7980_03425	COG2182	Extracellular solute-binding protein
N7980_03430	COG1175	transmembrane transport
N7980_03435	COG3833	ABC-type maltose transport systems, permease component
N7980_03440	COG5521	maltodextrose utilization protein MalA
N7980_03445	COG1554	hydrolase, family 65, central catalytic
N7980_03450	COG0366	Alpha amylase catalytic
N7980_03455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7980_03460	COG0740	serine-type endopeptidase activity
N7980_03475	COG2076	Multidrug Resistance protein
N7980_03480	COG2076	Multidrug Resistance protein
N7980_03485	COG1309	transcriptional regulator
N7980_03490	COG0531	amino acid
N7980_03495	COG1621	beta-fructofuranosidase activity
N7980_03500	COG1621	beta-fructofuranosidase activity
N7980_03505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7980_03510	COG1794	racemase activity, acting on amino acids and derivatives
N7980_03520	COG3479	Phenolic acid decarboxylase
N7980_03530	COG2272	Belongs to the type-B carboxylesterase lipase family
N7980_03535	COG1396	sequence-specific DNA binding
N7980_03545	COG0489	protein tyrosine kinase activity
N7980_03550	COG1086	Polysaccharide biosynthesis protein
N7980_03555	COG0438	transferase activity, transferring glycosyl groups
N7980_03560	COG1215	transferase activity, transferring glycosyl groups
N7980_03565	COG0438	transferase activity, transferring glycosyl groups
N7980_03575	COG1216	Glycosyl transferase, family 2
N7980_03580	COG5039	Polysaccharide pyruvyl transferase
N7980_03585	COG1216	Glycosyl transferase, family 2
N7980_03590	COG2244	polysaccharide biosynthetic process
N7980_03595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N7980_03600	COG0110	maltose O-acetyltransferase activity
N7980_03605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N7980_03610	COG5039	Polysaccharide pyruvyl transferase
N7980_03620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N7980_03625	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N7980_03630	COG1620	l-lactate permease
N7980_03635	COG2186	Transcriptional regulator
N7980_03640	COG1609	Transcriptional regulator
N7980_03645	COG2182	Extracellular solute-binding protein
N7980_03650	COG1175	transmembrane transport
N7980_03655	COG3833	ABC-type maltose transport systems, permease component
N7980_03660	COG1874	Beta-galactosidase
N7980_03665	COG3867	Arabinogalactan endo-beta-1,4-galactanase
N7980_03670	COG2208	phosphoserine phosphatase activity
N7980_03675	COG0596	Alpha beta hydrolase
N7980_03680	COG1131	(ABC) transporter
N7980_03685	COG0842	Transport permease protein
N7980_03690	COG4585	Histidine kinase
N7980_03695	COG2197	response regulator
N7980_03700	COG0247	lactate metabolic process
N7980_03705	COG1139	Iron-sulfur cluster binding protein
N7980_03710	COG1556	Lactate utilization protein
N7980_03715	COG3858	chitin binding
N7980_03720	COG1113	amino acid transport
N7980_03725	COG0697	spore germination
N7980_03730	COG0583	DNA-binding transcription factor activity
N7980_03735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7980_03740	COG1609	Transcriptional regulator
N7980_03745	COG2814	Major facilitator Superfamily
N7980_03750	COG2390	Transcriptional regulator
N7980_03755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N7980_03760	COG0126	phosphoglycerate kinase activity
N7980_03765	COG0149	triose-phosphate isomerase activity
N7980_03770	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N7980_03775	COG0148	phosphopyruvate hydratase activity
N7980_03780	COG0456	acetyltransferase
N7980_03785	COG4640	response to antibiotic
N7980_03790	COG3064	Membrane
N7980_03800	COG2095	MarC family integral membrane protein
N7980_03805	COG1510	regulation of RNA biosynthetic process
N7980_03810	COG0517	IMP dehydrogenase activity
N7980_03810	COG1125	glycine betaine transport
N7980_03815	COG1174	glycine betaine transport
N7980_03820	COG1732	Glycine betaine
N7980_03825	COG1174	glycine betaine transport
N7980_03830	COG1510	regulation of RNA biosynthetic process
N7980_03835	COG1125	glycine betaine transport
N7980_03835	COG0517	IMP dehydrogenase activity
N7980_03840	COG1174	glycine betaine transport
N7980_03845	COG1732	Glycine betaine
N7980_03850	COG1174	glycine betaine transport
N7980_03880	COG1131	(ABC) transporter
N7980_03905	COG0840	transmembrane signaling receptor activity
N7980_03910	COG1733	regulation of RNA biosynthetic process
N7980_03915	COG1396	sequence-specific DNA binding
N7980_03920	COG1396	sequence-specific DNA binding
N7980_03925	COG1476	TRANSCRIPTIONal
N7980_03930	COG0596	Alpha beta hydrolase
N7980_03935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N7980_03940	COG1647	Serine aminopeptidase, S33
N7980_03945	COG0557	exoribonuclease II activity
N7980_03950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N7980_03975	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_03980	COG1309	transcriptional regulator
N7980_03985	COG2076	Multidrug Resistance protein
N7980_03995	COG1289	transmembrane transporter activity
N7980_04000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7980_04005	COG0673	inositol 2-dehydrogenase activity
N7980_04010	COG1937	Protein conserved in bacteria
N7980_04015	COG2608	mercury ion transmembrane transporter activity
N7980_04020	COG2217	Heavy metal translocating P-type atpase
N7980_04025	COG2217	Heavy metal translocating P-type atpase
N7980_04030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N7980_04035	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
N7980_04040	COG2860	membrane
N7980_04050	COG3973	AAA domain
N7980_04055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N7980_04060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7980_04065	COG0025	NhaP-type Na H and K H
N7980_04075	COG0656	L-ascorbic acid biosynthetic process
N7980_04080	COG4149	molybdate abc transporter
N7980_04085	COG0725	ABC transporter, periplasmic molybdate-binding protein
N7980_04090	COG1910	domain protein
N7980_04095	COG1368	sulfuric ester hydrolase activity
N7980_04100	COG1988	membrane-bound metal-dependent
N7980_04110	COG0531	amino acid
N7980_04115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7980_04120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7980_04125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7980_04130	COG1120	ATPase activity
N7980_04135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7980_04140	COG1136	(ABC) transporter
N7980_04145	COG0577	efflux transmembrane transporter activity
N7980_04155	COG2140	Oxalate decarboxylase
N7980_04165	COG1191	sigma factor activity
N7980_04175	COG0745	RESPONSE REGULATOR receiver
N7980_04180	COG2205	protein histidine kinase activity
N7980_04185	COG3386	PFAM SMP-30 Gluconolaconase
N7980_04190	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_04195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7980_04200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7980_04205	COG1120	ATPase activity
N7980_04210	COG2096	Adenosyltransferase
N7980_04215	COG2814	Major facilitator Superfamily
N7980_04220	COG4758	membrane
N7980_04225	COG1842	Phage shock protein A
N7980_04230	COG3595	metallopeptidase activity
N7980_04235	COG4758	membrane
N7980_04240	COG4585	Histidine kinase
N7980_04245	COG2197	response regulator
N7980_04255	COG0814	amino acid
N7980_04260	COG0697	spore germination
N7980_04270	COG0114	fumarate hydratase activity
N7980_04275	COG1309	transcriptional regulator
N7980_04285	COG2205	protein histidine kinase activity
N7980_04285	COG2770	Histidine kinase
N7980_04290	COG0745	RESPONSE REGULATOR receiver
N7980_04295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7980_04300	COG0783	Belongs to the Dps family
N7980_04305	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_04320	COG1120	ATPase activity
N7980_04330	COG0583	DNA-binding transcription factor activity
N7980_04340	COG1942	4-Oxalocrotonate Tautomerase
N7980_04345	COG0477	Major facilitator Superfamily
N7980_04350	COG1846	Transcriptional regulator
N7980_04355	COG5577	PFAM Coat F domain
N7980_04365	COG0506	proline dehydrogenase activity
N7980_04375	COG1024	Enoyl-CoA hydratase
N7980_04375	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7980_04380	COG0183	Belongs to the thiolase family
N7980_04385	COG1960	acyl-CoA dehydrogenase activity
N7980_04390	COG1393	Belongs to the ArsC family
N7980_04395	COG0509	glycine decarboxylation via glycine cleavage system
N7980_04405	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N7980_04410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7980_04420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N7980_04425	COG2011	ABC-type metal ion transport system permease component
N7980_04430	COG1464	Belongs to the NlpA lipoprotein family
N7980_04435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7980_04445	COG0396	ATPase activity
N7980_04450	COG0719	Fe-S assembly protein
N7980_04455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N7980_04460	COG0822	iron-sulfur transferase activity
N7980_04465	COG0719	Fe-S assembly protein
N7980_04470	COG0640	Transcriptional regulator
N7980_04475	COG0346	lactoylglutathione lyase activity
N7980_04490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7980_04495	COG0322	excinuclease ABC activity
N7980_04500	COG2222	sugar isomerase
N7980_04505	COG1653	transport
N7980_04510	COG1175	transmembrane transport
N7980_04515	COG0395	ABC-type sugar transport system, permease component
N7980_04520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7980_04525	COG2188	Transcriptional regulator
N7980_04530	COG3842	ATPase activity
N7980_04535	COG2356	endonuclease I
N7980_04545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7980_04550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N7980_04555	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N7980_04560	COG2068	MobA-Related Protein
N7980_04565	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
N7980_04570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N7980_04575	COG2080	2 iron, 2 sulfur cluster binding
N7980_04585	COG2351	hydroxyisourate hydrolase activity
N7980_04590	COG3195	allantoin biosynthetic process
N7980_04590	COG3648	Uricase
N7980_04595	COG2233	PERMEase
N7980_04600	COG2233	PERMEase
N7980_04605	COG2508	Transcriptional regulator
N7980_04610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N7980_04620	COG1801	Protein of unknown function DUF72
N7980_04625	COG0730	response to heat
N7980_04630	COG0737	Belongs to the 5'-nucleotidase family
N7980_04635	COG3377	Domain of unknown function (DUF1805)
N7980_04645	COG0739	heme binding
N7980_04650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N7980_04660	COG4470	Protein conserved in bacteria
N7980_04665	COG2445	Protein of unknown function DUF86
N7980_04670	COG0647	UMP catabolic process
N7980_04675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N7980_04680	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7980_04685	COG0460	homoserine dehydrogenase
N7980_04690	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N7980_04695	COG0083	homoserine kinase activity
N7980_04700	COG0823	Involved in the tonB-independent uptake of proteins
N7980_04700	COG1506	peptidase
N7980_04700	COG4946	Tricorn protease homolog
N7980_04705	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N7980_04710	COG4837	Protein of unknown function (DUF1462)
N7980_04715	COG1252	NADH dehydrogenase
N7980_04720	COG4844	belongs to the
N7980_04725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N7980_04730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N7980_04735	COG0316	Belongs to the HesB IscA family
N7980_04740	COG0456	acetyltransferase
N7980_04745	COG2808	Putative FMN-binding domain
N7980_04750	COG0516	GMP reductase activity
N7980_04760	COG0492	ferredoxin-NADP+ reductase activity
N7980_04765	COG1252	NADH dehydrogenase
N7980_04780	COG3584	3D domain protein
N7980_04785	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
N7980_04790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N7980_04795	COG2056	Na+-H+ antiporter family
N7980_04800	COG1268	BioY protein
N7980_04805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N7980_04810	COG2819	hydrolase of the alpha beta superfamily
N7980_04815	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_04820	COG1169	isochorismate synthase
N7980_04825	COG1021	2,3-dihydroxybenzoate-AMP ligase
N7980_04830	COG1535	isochorismatase
N7980_04830	COG3433	isochorismatase activity
N7980_04835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_04840	COG3251	PFAM MbtH domain protein
N7980_04845	COG5634	Uncharacterized conserved protein (DUF2278)
N7980_04850	COG0686	Belongs to the AlaDH PNT family
N7980_04855	COG2508	Transcriptional regulator
N7980_04855	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N7980_04860	COG4842	Belongs to the WXG100 family
N7980_04865	COG5417	Belongs to the EsaB family
N7980_04870	COG4499	WXG100 protein secretion system (Wss), protein YukC
N7980_04875	COG0433	COG0433 Predicted ATPase
N7980_04875	COG1674	ftsk spoiiie
N7980_04880	COG1511	domain protein
N7980_04890	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_04895	COG1418	mRNA catabolic process
N7980_04910	COG0628	permease
N7980_04925	COG5506	Protein of unknown function (DUF1694)
N7980_04930	COG1335	isochorismatase
N7980_04935	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N7980_04940	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N7980_04960	COG0142	geranyltranstransferase activity
N7980_04970	COG4585	Histidine kinase
N7980_04975	COG2197	response regulator
N7980_04980	COG2050	protein possibly involved in aromatic compounds catabolism
N7980_04985	COG1320	monovalent cation:proton antiporter activity
N7980_04990	COG2212	antiporter activity
N7980_04995	COG1863	multisubunit Na H antiporter MnhE subunit
N7980_05000	COG0651	ATP synthesis coupled electron transport
N7980_05005	COG1006	Multisubunit Na H antiporter MnhC subunit
N7980_05010	COG2111	Na H antiporter
N7980_05015	COG2111	Na H antiporter
N7980_05015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N7980_05025	COG3493	citrate carrier protein
N7980_05030	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7980_05035	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7980_05040	COG3845	ABC transporter
N7980_05045	COG1744	ABC transporter substrate-binding protein PnrA-like
N7980_05050	COG4565	transcriptional regulatory protein
N7980_05055	COG3290	protein histidine kinase activity
N7980_05065	COG3011	Protein conserved in bacteria
N7980_05070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7980_05075	COG2814	Major facilitator Superfamily
N7980_05085	COG5018	Exonuclease
N7980_05095	COG2205	protein histidine kinase activity
N7980_05100	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
N7980_05110	COG2267	carboxylic ester hydrolase activity
N7980_05115	COG1522	sequence-specific DNA binding
N7980_05120	COG0436	Aminotransferase
N7980_05125	COG1098	S1 RNA binding domain
N7980_05130	COG2155	Conserved Protein
N7980_05135	COG1979	alcohol dehydrogenase
N7980_05140	COG1979	alcohol dehydrogenase
N7980_05145	COG0166	Belongs to the GPI family
N7980_05160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N7980_05175	COG2738	Putative neutral zinc metallopeptidase
N7980_05180	COG1253	flavin adenine dinucleotide binding
N7980_05185	COG0366	Alpha amylase catalytic
N7980_05195	COG0432	Pfam Uncharacterised protein family UPF0047
N7980_05210	COG0840	transmembrane signaling receptor activity
N7980_05215	COG0840	transmembrane signaling receptor activity
N7980_05220	COG0840	transmembrane signaling receptor activity
N7980_05225	COG0840	transmembrane signaling receptor activity
N7980_05230	COG3347	Dehydrogenase
N7980_05230	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_05235	COG1349	DNA-binding transcription factor activity
N7980_05240	COG1070	Carbohydrate kinase
N7980_05245	COG3254	rhamnose metabolic process
N7980_05250	COG4806	L-rhamnose isomerase
N7980_05255	COG0673	inositol 2-dehydrogenase activity
N7980_05260	COG0628	permease
N7980_05265	COG1968	undecaprenyl-diphosphatase activity
N7980_05275	COG5553	Cysteine dioxygenase type I
N7980_05280	COG0477	Major facilitator Superfamily
N7980_05285	COG1705	Flagellar rod assembly protein muramidase FlgJ
N7980_05290	COG4682	membrane
N7980_05295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N7980_05300	COG0569	domain protein
N7980_05310	COG1510	regulation of RNA biosynthetic process
N7980_05315	COG1012	belongs to the aldehyde dehydrogenase family
N7980_05320	COG1454	alcohol dehydrogenase
N7980_05330	COG2318	DinB family
N7980_05335	COG1585	Membrane protein implicated in regulation of membrane protease activity
N7980_05340	COG2268	Band 7 protein
N7980_05345	COG1247	-acetyltransferase
N7980_05350	COG3859	Proton-coupled thiamine transporter YuaJ
N7980_05475	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N7980_05480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N7980_05485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N7980_05490	COG0297	glycogen (starch) synthase activity
N7980_05495	COG0058	SHG alpha-glucan phosphorylase activity
N7980_05500	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
N7980_05505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7980_05510	COG0438	transferase activity, transferring glycosyl groups
N7980_05515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7980_05525	COG0438	transferase activity, transferring glycosyl groups
N7980_05530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7980_05535	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N7980_05540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7980_05545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N7980_05550	COG1169	isochorismate synthase
N7980_05555	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N7980_05560	COG0596	Alpha beta hydrolase
N7980_05565	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
N7980_05570	COG0318	PFAM AMP-dependent synthetase and ligase
N7980_05575	COG4948	Mandelate Racemase Muconate Lactonizing
N7980_05580	COG0803	Belongs to the bacterial solute-binding protein 9 family
N7980_05585	COG1121	(ABC) transporter
N7980_05590	COG1321	iron dependent repressor
N7980_05590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7980_05595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7980_05605	COG1294	oxidase, subunit
N7980_05610	COG1271	oxidase subunit
N7980_05615	COG0254	rRNA binding
N7980_05620	COG0288	reversible hydration of carbon dioxide
N7980_05625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N7980_05630	COG1854	S-ribosylhomocysteine lyase activity
N7980_05645	COG0783	Belongs to the Dps family
N7980_05650	COG4824	toxin secretion phage lysis holin
N7980_05655	COG0494	nUDIX hydrolase
N7980_05660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7980_05665	COG1116	anion transmembrane transporter activity
N7980_05670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7980_05675	COG1506	peptidase
N7980_05685	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N7980_05690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N7980_05695	COG0367	asparagine synthase
N7980_05700	COG1113	amino acid transport
N7980_05705	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N7980_05710	COG2267	carboxylic ester hydrolase activity
N7980_05720	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
N7980_05725	COG1242	4 iron, 4 sulfur cluster binding
N7980_05740	COG1725	Transcriptional regulator
N7980_05745	COG1131	(ABC) transporter
N7980_05760	COG1136	(ABC) transporter
N7980_05765	COG0577	efflux transmembrane transporter activity
N7980_05770	COG0745	RESPONSE REGULATOR receiver
N7980_05775	COG2205	protein histidine kinase activity
N7980_05780	COG1136	(ABC) transporter
N7980_05785	COG0577	efflux transmembrane transporter activity
N7980_05790	COG2433	Pfam Transposase IS66
N7980_05795	COG2814	Major facilitator Superfamily
N7980_05800	COG2202	Pas domain
N7980_05800	COG1366	Belongs to the anti-sigma-factor antagonist family
N7980_05810	COG0495	leucyl-tRNA aminoacylation
N7980_05815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N7980_05820	COG1486	melibiose metabolic process
N7980_05825	COG0395	ABC-type sugar transport system, permease component
N7980_05830	COG1175	transmembrane transport
N7980_05835	COG1653	transport
N7980_05840	COG1609	Transcriptional regulator
N7980_05845	COG1073	alpha beta
N7980_05855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7980_05860	COG0156	8-amino-7-oxononanoate synthase activity
N7980_05870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N7980_05875	COG2124	cytochrome p450
N7980_05880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7980_05885	COG0395	ABC-type sugar transport system, permease component
N7980_05890	COG1653	transport
N7980_05895	COG2207	Transcriptional regulator
N7980_05900	COG4209	transmembrane transport
N7980_05905	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N7980_05910	COG1653	transport
N7980_05915	COG0673	inositol 2-dehydrogenase activity
N7980_05920	COG5578	integral membrane protein
N7980_05930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N7980_05935	COG2081	HI0933 family
N7980_05940	COG2244	polysaccharide biosynthetic process
N7980_05945	COG1187	pseudouridine synthase activity
N7980_05950	COG1349	DNA-binding transcription factor activity
N7980_05955	COG1131	(ABC) transporter
N7980_05960	COG4473	ABC transporter
N7980_05965	COG2252	PERMEase
N7980_05970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7980_05975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7980_05980	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N7980_05990	COG1597	lipid kinase activity
N7980_05995	COG1523	belongs to the glycosyl hydrolase 13 family
N7980_06000	COG0510	thiamine kinase activity
N7980_06010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N7980_06015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7980_06020	COG0281	malic enzyme
N7980_06025	COG5584	Small secreted protein
N7980_06030	COG1363	Peptidase, m42
N7980_06045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7980_06050	COG4848	Belongs to the UPF0354 family
N7980_06055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7980_06060	COG1674	ftsk spoiiie
N7980_06065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N7980_06070	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N7980_06075	COG4980	gas vesicle protein
N7980_06080	COG3118	belongs to the thioredoxin family
N7980_06085	COG1605	Chorismate mutase
N7980_06085	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
N7980_06090	COG1609	Transcriptional regulator
N7980_06095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N7980_06100	COG1360	Flagellar Motor Protein
N7980_06105	COG0123	including yeast histone deacetylase and acetoin utilization protein
N7980_06110	COG0517	IMP dehydrogenase activity
N7980_06115	COG0454	-acetyltransferase
N7980_06120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7980_06125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N7980_06135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N7980_06140	COG2199	diguanylate cyclase activity
N7980_06140	COG2203	Gaf domain
N7980_06145	COG1956	GAF domain-containing protein
N7980_06150	COG1309	transcriptional regulator
N7980_06155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N7980_06160	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
N7980_06165	COG1114	Component of the transport system for branched-chain amino acids
N7980_06170	COG1104	cysteine desulfurase activity
N7980_06175	COG0301	tRNA thio-modification
N7980_06185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7980_06190	COG1574	metal-dependent hydrolase with the TIM-barrel fold
N7980_06195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N7980_06200	COG0616	signal peptide processing
N7980_06205	COG1714	RDD family
N7980_06215	COG3874	Sporulation protein YtfJ
N7980_06220	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
N7980_06225	COG0827	DNA restriction-modification system
N7980_06235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N7980_06240	COG0521	Mo-molybdopterin cofactor biosynthetic process
N7980_06245	COG0137	argininosuccinate synthase activity
N7980_06250	COG0165	Argininosuccinate lyase
N7980_06260	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_06265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N7980_06270	COG0583	DNA-binding transcription factor activity
N7980_06275	COG0454	-acetyltransferase
N7980_06280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7980_06285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7980_06290	COG0765	amino acid transport
N7980_06295	COG0765	amino acid transport
N7980_06300	COG1126	abc transporter atp-binding protein
N7980_06305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7980_06310	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N7980_06315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7980_06320	COG0196	riboflavin kinase activity
N7980_06325	COG1473	amidohydrolase
N7980_06330	COG0730	response to heat
N7980_06335	COG4109	DRTGG domain
N7980_06345	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N7980_06365	COG0587	DNA-directed DNA polymerase activity
N7980_06370	COG0281	malic enzyme
N7980_06375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N7980_06380	COG0825	malonyl-CoA metabolic process
N7980_06385	COG0205	6-phosphofructokinase activity
N7980_06390	COG0469	pyruvate kinase activity
N7980_06395	COG3030	protein affecting phage T7 exclusion by the F plasmid
N7980_06400	COG0628	permease
N7980_06405	COG2707	UPF0756 membrane protein
N7980_06410	COG0372	Belongs to the citrate synthase family
N7980_06415	COG0538	isocitrate dehydrogenase activity
N7980_06420	COG0039	L-malate dehydrogenase activity
N7980_06425	COG0745	RESPONSE REGULATOR receiver
N7980_06430	COG5002	protein histidine kinase activity
N7980_06435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7980_06435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7980_06440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N7980_06445	COG1971	Probably functions as a manganese efflux pump
N7980_06450	COG0237	dephospho-CoA kinase activity
N7980_06455	COG0656	L-ascorbic acid biosynthetic process
N7980_06460	COG2814	Major facilitator Superfamily
N7980_06465	COG1733	regulation of RNA biosynthetic process
N7980_06470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N7980_06475	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
N7980_06480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N7980_06485	COG3611	Membrane attachment protein
N7980_06490	COG1484	DNA-dependent DNA replication
N7980_06495	COG0398	Pfam SNARE associated Golgi protein
N7980_06505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N7980_06510	COG1011	Hydrolase
N7980_06515	COG3275	phosphorelay sensor kinase activity
N7980_06520	COG3279	Response regulator of the LytR AlgR family
N7980_06525	COG1380	Effector of murein hydrolase LrgA
N7980_06530	COG1346	cytolysis
N7980_06540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N7980_06545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N7980_06550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N7980_06555	COG3326	Membrane
N7980_06565	COG1363	Peptidase, m42
N7980_06570	COG3507	Belongs to the glycosyl hydrolase 43 family
N7980_06575	COG2160	L-arabinose isomerase activity
N7980_06580	COG1069	ribulokinase activity
N7980_06585	COG0235	Class ii aldolase
N7980_06590	COG0647	UMP catabolic process
N7980_06595	COG0371	Dehydrogenase
N7980_06600	COG1653	transport
N7980_06605	COG1175	transmembrane transport
N7980_06610	COG0395	ABC-type sugar transport system, permease component
N7980_06615	COG3534	alpha-L-arabinofuranosidase
N7980_06620	COG1966	Carbon starvation protein
N7980_06630	COG0346	lactoylglutathione lyase activity
N7980_06635	COG0247	lactate metabolic process
N7980_06640	COG0277	FAD linked oxidase domain protein
N7980_06645	COG3835	regulator
N7980_06655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7980_06665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N7980_06670	COG0072	phenylalanine-tRNA ligase activity
N7980_06670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7980_06675	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N7980_06680	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
N7980_06685	COG1286	toxin biosynthetic process
N7980_06690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N7980_06690	COG1796	DNA polymerase
N7980_06695	COG1193	negative regulation of DNA recombination
N7980_06700	COG3766	membrane
N7980_06705	COG0318	PFAM AMP-dependent synthetase and ligase
N7980_06710	COG1309	transcriptional regulator
N7980_06715	COG1024	Enoyl-CoA hydratase
N7980_06720	COG2086	electron transfer activity
N7980_06725	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N7980_06730	COG3534	alpha-L-arabinofuranosidase
N7980_06735	COG3118	belongs to the thioredoxin family
N7980_06740	COG0322	excinuclease ABC activity
N7980_06745	COG0527	aspartate kinase activity
N7980_06750	COG1719	4-vinyl reductase, 4VR
N7980_06755	COG2009	succinate dehydrogenase
N7980_06760	COG1053	succinate dehydrogenase
N7980_06765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N7980_06770	COG0824	Thioesterase
N7980_06775	COG2197	response regulator
N7980_06780	COG1846	Transcriptional regulator
N7980_06785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N7980_06790	COG5401	PFAM Sporulation and spore germination
N7980_06795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N7980_06800	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N7980_06805	COG0622	Phosphoesterase
N7980_06815	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
N7980_06820	COG0454	-acetyltransferase
N7980_06830	COG0028	Belongs to the TPP enzyme family
N7980_06835	COG0440	acetolactate synthase activity
N7980_06840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N7980_06845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7980_06850	COG0473	3-isopropylmalate dehydrogenase activity
N7980_06855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N7980_06860	COG0066	3-isopropylmalate dehydratase activity
N7980_06865	COG1477	protein flavinylation
N7980_06865	COG0457	Tetratricopeptide repeat
N7980_06870	COG0544	peptidyl-prolyl cis-trans isomerase activity
N7980_06875	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N7980_06880	COG1067	ATP-dependent peptidase activity
N7980_06880	COG0470	DNA polymerase III
N7980_06885	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N7980_06890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
N7980_06900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N7980_06905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N7980_06910	COG0181	hydroxymethylbilane synthase activity
N7980_06915	COG1587	Uroporphyrinogen-III synthase
N7980_06920	COG0113	porphobilinogen synthase activity
N7980_06925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N7980_06930	COG1388	LysM domain
N7980_06935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7980_06945	COG0525	valine-tRNA ligase activity
N7980_06950	COG0285	dihydrofolate synthase activity
N7980_06955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
N7980_06965	COG0424	maF-like protein
N7980_06970	COG2003	Belongs to the UPF0758 family
N7980_06975	COG1077	Cell shape determining protein MreB Mrl
N7980_06985	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N7980_06990	COG0850	regulation of cytokinetic process
N7980_06995	COG2894	cell division
N7980_07000	COG0739	heme binding
N7980_07005	COG1994	Peptidase M50
N7980_07010	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N7980_07015	COG2868	ribosomal protein
N7980_07020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N7980_07030	COG3290	protein histidine kinase activity
N7980_07035	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N7980_07040	COG4492	Belongs to the UPF0735 family
N7980_07045	COG0077	Prephenate dehydratase
N7980_07050	COG1827	regulation of RNA biosynthetic process
N7980_07055	COG1104	cysteine desulfurase activity
N7980_07060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N7980_07065	COG0157	Belongs to the NadC ModD family
N7980_07070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N7980_07075	COG1388	LysM domain
N7980_07085	COG0217	transcriptional regulatory protein
N7980_07090	COG1115	amino acid carrier protein
N7980_07110	COG2112	serine threonine protein kinase
N7980_07115	COG0673	inositol 2-dehydrogenase activity
N7980_07120	COG2814	Major facilitator Superfamily
N7980_07130	COG0632	four-way junction helicase activity
N7980_07135	COG2255	four-way junction helicase activity
N7980_07145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N7980_07150	COG0343	queuine tRNA-ribosyltransferase activity
N7980_07155	COG1862	Preprotein translocase
N7980_07165	COG2323	membrane
N7980_07170	COG2244	polysaccharide biosynthetic process
N7980_07180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N7980_07180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N7980_07185	COG0490	domain, Protein
N7980_07190	COG5416	Lipopolysaccharide assembly protein A domain
N7980_07195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N7980_07195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
N7980_07200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7980_07205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N7980_07210	COG1490	D-aminoacyl-tRNA deacylase activity
N7980_07215	COG4991	sh3 domain protein
N7980_07215	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7980_07215	COG3103	Sh3 type 3 domain protein
N7980_07225	COG0124	histidyl-tRNA synthetase
N7980_07230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N7980_07240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N7980_07245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N7980_07250	COG1959	2 iron, 2 sulfur cluster binding
N7980_07255	COG1104	cysteine desulfurase activity
N7980_07260	COG0482	sulfurtransferase activity
N7980_07265	COG0457	Tetratricopeptide repeat
N7980_07270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7980_07275	COG3881	PFAM PRC-barrel domain
N7980_07290	COG0765	amino acid transport
N7980_07295	COG0765	amino acid transport
N7980_07300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7980_07305	COG1126	abc transporter atp-binding protein
N7980_07310	COG0628	permease
N7980_07315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N7980_07320	COG4472	Bacterial protein of unknown function (DUF965)
N7980_07325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N7980_07330	COG3906	Belongs to the UPF0473 family
N7980_07335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N7980_07340	COG4122	O-methyltransferase activity
N7980_07345	COG0826	peptidase U32
N7980_07350	COG0826	peptidase U32
N7980_07355	COG0572	uridine kinase
N7980_07360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7980_07365	COG0768	penicillin binding
N7980_07380	COG2226	methyltransferase
N7980_07385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N7980_07390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7980_07395	COG0626	cystathionine gamma-synthase activity
N7980_07405	COG2427	Protein of unknown function (DUF1641)
N7980_07410	COG3383	formate dehydrogenase (NAD+) activity
N7980_07415	COG5609	conserved protein (DUF2294)
N7980_07420	COG2116	formate transmembrane transporter activity
N7980_07435	COG2226	methyltransferase
N7980_07440	COG1309	transcriptional regulator
N7980_07445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N7980_07445	COG2124	cytochrome p450
N7980_07455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N7980_07455	COG2755	lipolytic protein G-D-S-L family
N7980_07465	COG1595	DNA-templated transcription, initiation
N7980_07470	COG1378	Sugar-specific transcriptional regulator TrmB
N7980_07475	COG1280	lysine exporter protein (LysE YggA)
N7980_07480	COG1113	amino acid transport
N7980_07490	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N7980_07490	COG3933	PFAM sigma-54 factor interaction domain-containing protein
N7980_07495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7980_07500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_07505	COG3715	PTS system
N7980_07510	COG3716	PTS system mannose fructose sorbose family IID component
N7980_07520	COG1621	beta-fructofuranosidase activity
N7980_07525	COG0693	protein deglycase activity
N7980_07530	COG1064	alcohol dehydrogenase
N7980_07540	COG0789	Transcriptional regulator
N7980_07545	COG5577	PFAM Coat F domain
N7980_07555	COG1063	alcohol dehydrogenase
N7980_07560	COG5577	PFAM Coat F domain
N7980_07570	COG0346	lactoylglutathione lyase activity
N7980_07580	COG4991	sh3 domain protein
N7980_07585	COG4991	sh3 domain protein
N7980_07590	COG0596	Alpha beta hydrolase
N7980_07595	COG5566	PFAM Mor transcription activator
N7980_07600	COG3409	Peptidoglycan-binding domain 1 protein
N7980_07605	COG2828	Protein conserved in bacteria
N7980_07610	COG0583	DNA-binding transcription factor activity
N7980_07615	COG2851	Citrate transporter
N7980_07620	COG0667	Aldo Keto reductase
N7980_07625	COG1595	DNA-templated transcription, initiation
N7980_07630	COG3443	Belongs to the bacterial solute-binding protein 9 family
N7980_07635	COG1846	Transcriptional regulator
N7980_07640	COG0477	Major facilitator Superfamily
N7980_07645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N7980_07650	COG3958	Transketolase
N7980_07655	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_07670	COG2186	Transcriptional regulator
N7980_07680	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N7980_07685	COG2070	2-Nitropropane dioxygenase
N7980_07695	COG2318	DinB family
N7980_07710	COG1335	isochorismatase
N7980_07720	COG2124	cytochrome p450
N7980_07725	COG2732	(Barnase) inhibitor
N7980_07730	COG1522	sequence-specific DNA binding
N7980_07735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N7980_07740	COG1687	branched-chain amino acid
N7980_07745	COG1114	Component of the transport system for branched-chain amino acids
N7980_07755	COG0583	DNA-binding transcription factor activity
N7980_07760	COG1942	4-Oxalocrotonate Tautomerase
N7980_07765	COG1230	cation diffusion facilitator family transporter
N7980_07770	COG2072	flavoprotein involved in K transport
N7980_07775	COG0583	DNA-binding transcription factor activity
N7980_07780	COG0697	spore germination
N7980_07790	COG1253	flavin adenine dinucleotide binding
N7980_07795	COG0456	acetyltransferase
N7980_07800	COG2814	Major facilitator Superfamily
N7980_07805	COG4978	Transcriptional regulator
N7980_07805	COG0789	Transcriptional regulator
N7980_07820	COG0662	Cupin 2, conserved barrel domain protein
N7980_07830	COG1937	Protein conserved in bacteria
N7980_07835	COG2210	Belongs to the sulfur carrier protein TusA family
N7980_07845	COG0425	Belongs to the sulfur carrier protein TusA family
N7980_07845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N7980_07860	COG0425	Belongs to the sulfur carrier protein TusA family
N7980_07865	COG0730	response to heat
N7980_07875	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7980_07880	COG0454	-acetyltransferase
N7980_07890	COG2311	Membrane
N7980_07895	COG0745	RESPONSE REGULATOR receiver
N7980_07900	COG0642	Histidine kinase
N7980_07900	COG5002	protein histidine kinase activity
N7980_07905	COG3223	Belongs to the PsiE family
N7980_07930	COG2856	Zn peptidase
N7980_07935	COG0563	adenylate kinase activity
N7980_07945	COG3620	sequence-specific DNA binding
N7980_07950	COG1476	TRANSCRIPTIONal
N7980_07980	COG5377	YqaJ viral recombinase family
N7980_07985	COG3723	Recombinational DNA repair protein, rece pathway
N7980_07990	COG3935	DnaD domain protein
N7980_07995	COG1484	DNA-dependent DNA replication
N7980_08005	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
N7980_08020	COG3677	Transposase
N7980_08030	COG5484	DNA packaging
N7980_08035	COG1783	phage Terminase large subunit
N7980_08040	COG5518	Phage portal protein
N7980_08045	COG2369	cell adhesion
N7980_08055	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N7980_08060	COG4653	Phage capsid family
N7980_08125	COG5280	Phage tail tape measure protein TP901
N7980_08125	COG3953	SLT domain
N7980_08130	COG1652	LysM domain
N7980_08135	COG4193	domain, Protein
N7980_08145	COG3628	GPW Gp25 family protein
N7980_08150	COG3299	homolog of phage Mu protein gp47
N7980_08155	COG3778	Protein conserved in bacteria
N7980_08185	COG4824	toxin secretion phage lysis holin
N7980_08190	COG3409	Peptidoglycan-binding domain 1 protein
N7980_08190	COG5632	N-Acetylmuramoyl-L-alanine amidase
N7980_08215	COG5444	nuclease activity
N7980_08230	COG0457	Tetratricopeptide repeat
N7980_08235	COG3403	YqcI/YcgG family
N7980_08240	COG0640	Transcriptional regulator
N7980_08245	COG0346	lactoylglutathione lyase activity
N7980_08250	COG0798	PFAM Bile acid sodium symporter
N7980_08255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7980_08265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7980_08275	COG3209	COG3209 Rhs family protein
N7980_08285	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
N7980_08290	COG0398	Pfam SNARE associated Golgi protein
N7980_08295	COG5632	N-Acetylmuramoyl-L-alanine amidase
N7980_08295	COG3409	Peptidoglycan-binding domain 1 protein
N7980_08300	COG2755	lipolytic protein G-D-S-L family
N7980_08310	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
N7980_08315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N7980_08320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N7980_08325	COG1534	Rna-binding protein
N7980_08330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N7980_08335	COG1713	HD superfamily hydrolase involved in NAD metabolism
N7980_08340	COG0799	negative regulation of ribosome biogenesis
N7980_08345	COG2226	methyltransferase
N7980_08350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7980_08355	COG1596	polysaccharide export
N7980_08355	COG1555	photosystem II stabilization
N7980_08360	COG2131	deaminase
N7980_08365	COG2333	competence protein COMEC
N7980_08365	COG0658	competence protein
N7980_08380	COG1466	dna polymerase III delta subunit
N7980_08385	COG0268	Binds directly to 16S ribosomal RNA
N7980_08390	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
N7980_08395	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7980_08405	COG0481	GTPase activity
N7980_08410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7980_08415	COG1420	regulation of RNA biosynthetic process
N7980_08420	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N7980_08425	COG0443	Heat shock 70 kDa protein
N7980_08430	COG0484	heat shock protein binding
N7980_08435	COG2264	protein methyltransferase activity
N7980_08440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N7980_08445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7980_08450	COG1283	sodium-dependent phosphate transmembrane transporter activity
N7980_08460	COG1610	YqeY-like protein
N7980_08465	COG1030	water channel activity
N7980_08470	COG4864	UPF0365 protein
N7980_08485	COG0561	phosphatase activity
N7980_08490	COG1702	phosphate starvation-inducible protein PhoH
N7980_08495	COG1480	7TM receptor with intracellular HD hydrolase
N7980_08500	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N7980_08505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N7980_08510	COG0295	cytidine deaminase activity
N7980_08515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N7980_08525	COG1381	Involved in DNA repair and RecF pathway recombination
N7980_08530	COG0752	glycyl-tRNA synthetase alpha subunit
N7980_08535	COG0751	glycine-tRNA ligase activity
N7980_08540	COG0517	IMP dehydrogenase activity
N7980_08545	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N7980_08550	COG1671	Belongs to the UPF0178 family
N7980_08555	COG0358	DNA primase activity
N7980_08560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N7980_08565	COG2010	Cytochrome c
N7980_08570	COG2384	SAM-dependent methyltransferase
N7980_08575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N7980_08580	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N7980_08590	COG0513	Belongs to the DEAD box helicase family
N7980_08595	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N7980_08605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7980_08610	COG0735	belongs to the Fur family
N7980_08615	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
N7980_08620	COG4709	membrane
N7980_08625	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N7980_08630	COG1388	LysM domain
N7980_08635	COG5521	maltodextrose utilization protein MalA
N7980_08640	COG2839	Protein conserved in bacteria
N7980_08645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N7980_08650	COG0477	Major facilitator Superfamily
N7980_08655	COG0768	penicillin binding
N7980_08660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N7980_08665	COG0573	inorganic phosphate transmembrane transporter activity
N7980_08670	COG0581	inorganic phosphate transmembrane transporter activity
N7980_08675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7980_08680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7980_08685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N7980_08700	COG0438	transferase activity, transferring glycosyl groups
N7980_08710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N7980_08720	COG0705	Rhomboid family
N7980_08720	COG0457	Tetratricopeptide repeat
N7980_08725	COG4483	Protein conserved in bacteria
N7980_08730	COG1940	carbohydrate kinase activity
N7980_08735	COG1368	sulfuric ester hydrolase activity
N7980_08740	COG2866	Carboxypeptidase
N7980_08750	COG0011	TIGRFAM Protein of
N7980_08760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7980_08770	COG1393	Belongs to the ArsC family
N7980_08780	COG1366	Belongs to the anti-sigma-factor antagonist family
N7980_08785	COG1253	flavin adenine dinucleotide binding
N7980_08790	COG0598	Magnesium transport protein CorA
N7980_08795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N7980_08800	COG1459	type II secretion system
N7980_08805	COG4537	Required for transformation and DNA binding
N7980_08810	COG4970	Tfp pilus assembly protein FimT
N7980_08820	COG4940	Competence protein ComGF
N7980_08845	COG0681	Belongs to the peptidase S26 family
N7980_08855	COG1396	sequence-specific DNA binding
N7980_08870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N7980_08875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7980_08880	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N7980_08885	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N7980_08890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N7980_08895	COG0095	Lipoate-protein ligase
N7980_08900	COG1321	iron dependent repressor
N7980_08905	COG1752	Esterase of the alpha-beta hydrolase superfamily
N7980_08915	COG3872	metal-dependent enzyme
N7980_08925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N7980_08930	COG0006	proline dipeptidase activity
N7980_08935	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N7980_08945	COG3854	ATPases associated with a variety of cellular activities
N7980_08985	COG0511	ligase activity, forming carbon-carbon bonds
N7980_08990	COG0439	Biotin carboxylase
N7980_08995	COG1302	Protein conserved in bacteria
N7980_09000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7980_09005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N7980_09010	COG1570	exodeoxyribonuclease VII activity
N7980_09015	COG1722	exodeoxyribonuclease VII activity
N7980_09020	COG0142	geranyltranstransferase activity
N7980_09025	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N7980_09030	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
N7980_09035	COG1438	arginine binding
N7980_09040	COG0497	DNA recombination
N7980_09045	COG0750	zinc metalloprotease
N7980_09050	COG0745	RESPONSE REGULATOR receiver
N7980_09055	COG1902	pentaerythritol trinitrate reductase activity
N7980_09070	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7980_09075	COG0584	glycerophosphoryl diester phosphodiesterase
N7980_09080	COG0183	Belongs to the thiolase family
N7980_09085	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7980_09090	COG1960	acyl-CoA dehydrogenase activity
N7980_09095	COG0372	Belongs to the citrate synthase family
N7980_09100	COG2079	MmgE PrpD family protein
N7980_09105	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N7980_09115	COG3290	protein histidine kinase activity
N7980_09115	COG3829	transcription factor binding
N7980_09120	COG0280	phosphate acetyltransferase
N7980_09125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7980_09130	COG3426	butyrate kinase activity
N7980_09135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7980_09140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7980_09145	COG0022	dehydrogenase e1 component
N7980_09150	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7980_09155	COG0789	Transcriptional regulator
N7980_09155	COG4978	Transcriptional regulator
N7980_09160	COG2814	Major facilitator Superfamily
N7980_09165	COG1597	lipid kinase activity
N7980_09175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7980_09180	COG0765	amino acid transport
N7980_09185	COG1126	abc transporter atp-binding protein
N7980_09190	COG4129	membrane
N7980_09195	COG1376	ErfK ybiS ycfS ynhG family protein
N7980_09205	COG0346	lactoylglutathione lyase activity
N7980_09210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7980_09215	COG2195	Cleaves the N-terminal amino acid of tripeptides
N7980_09220	COG3361	conserved protein (COG2071)
N7980_09225	COG0706	membrane insertase activity
N7980_09235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7980_09240	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N7980_09245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N7980_09250	COG1234	tRNA 3'-trailer cleavage
N7980_09260	COG0596	Alpha beta hydrolase
N7980_09265	COG1902	pentaerythritol trinitrate reductase activity
N7980_09270	COG4187	Peptidase family M20/M25/M40
N7980_09275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7980_09280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7980_09285	COG0300	oxidoreductase activity
N7980_09290	COG3048	D-serine ammonia-lyase activity
N7980_09295	COG1072	(Pantothenic acid kinase))
N7980_09300	COG0346	lactoylglutathione lyase activity
N7980_09310	COG2211	Major facilitator Superfamily
N7980_09320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7980_09330	COG0456	acetyltransferase
N7980_09335	COG2329	Antibiotic biosynthesis monooxygenase
N7980_09340	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N7980_09340	COG0456	acetyltransferase
N7980_09345	COG4918	Iron-sulphur cluster biosynthesis
N7980_09355	COG1073	alpha beta
N7980_09365	COG0667	Aldo Keto reductase
N7980_09375	COG0494	nUDIX hydrolase
N7980_09380	COG1379	DNA repair
N7980_09385	COG1396	sequence-specific DNA binding
N7980_09390	COG0252	asparaginase activity
N7980_09395	COG1027	Aspartate ammonia-lyase
N7980_09400	COG1757	Na H antiporter
N7980_09405	COG0281	malic enzyme
N7980_09415	COG1300	Membrane
N7980_09420	COG0735	belongs to the Fur family
N7980_09430	COG4974	Belongs to the 'phage' integrase family
N7980_09435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N7980_09440	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
N7980_09445	COG1686	Belongs to the peptidase S11 family
N7980_09450	COG1366	Belongs to the anti-sigma-factor antagonist family
N7980_09455	COG2172	sigma factor antagonist activity
N7980_09460	COG1191	sigma factor activity
N7980_09480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7980_09495	COG0697	spore germination
N7980_09500	COG0019	diaminopimelate decarboxylase activity
N7980_09505	COG4086	secreted protein
N7980_09510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N7980_09530	COG0681	Belongs to the peptidase S26 family
N7980_09540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7980_09540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7980_09545	COG0307	riboflavin synthase, alpha
N7980_09550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7980_09550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7980_09555	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N7980_09560	COG0456	acetyltransferase
N7980_09565	COG1547	Domain of unknown function (DUF309)
N7980_09570	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N7980_09575	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7980_09585	COG1686	Belongs to the peptidase S11 family
N7980_09590	COG2715	membrane protein required for spore maturation
N7980_09595	COG0700	Nucleoside recognition
N7980_09600	COG1187	pseudouridine synthase activity
N7980_09605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7980_09610	COG1333	cytochrome c biogenesis protein
N7980_09615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N7980_09620	COG0745	RESPONSE REGULATOR receiver
N7980_09625	COG5002	protein histidine kinase activity
N7980_09630	COG1595	DNA-templated transcription, initiation
N7980_09640	COG0710	3-dehydroquinate dehydratase activity
N7980_09645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N7980_09650	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
N7980_09655	COG1141	Ferredoxin
N7980_09660	COG4955	Helix-turn-helix domain
N7980_09665	COG0514	ATP-dependent DNA helicase (RecQ)
N7980_09670	COG1266	CAAX protease self-immunity
N7980_09675	COG1388	LysM domain
N7980_09685	COG1408	metallophosphoesterase
N7980_09690	COG4862	establishment of competence for transformation
N7980_09695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7980_09700	COG0492	ferredoxin-NADP+ reductase activity
N7980_09705	COG2339	peptidase activity
N7980_09710	COG3773	Cell wall hydrolase
N7980_09710	COG3409	Peptidoglycan-binding domain 1 protein
N7980_09715	COG2959	enzyme of heme biosynthesis
N7980_09720	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
N7980_09730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N7980_09735	COG0539	negative regulation of cytoplasmic translation
N7980_09740	COG1304	FMN binding
N7980_09765	COG1160	GTP binding
N7980_09770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N7980_09785	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N7980_09790	COG0776	regulation of translation
N7980_09795	COG0302	gtp cyclohydrolase
N7980_09805	COG0142	geranyltranstransferase activity
N7980_09810	COG2226	methyltransferase
N7980_09815	COG0142	geranyltranstransferase activity
N7980_09820	COG0105	UTP biosynthetic process
N7980_09825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N7980_09830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N7980_09835	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N7980_09840	COG4401	Chorismate mutase type I
N7980_09845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N7980_09850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N7980_09860	COG0135	phosphoribosylanthranilate isomerase activity
N7980_09865	COG0133	tryptophan synthase activity
N7980_09875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N7980_09880	COG0287	Prephenate dehydrogenase
N7980_09885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N7980_09890	COG0457	Tetratricopeptide repeat
N7980_09895	COG5582	Belongs to the UPF0302 family
N7980_09905	COG0723	plastoquinol--plastocyanin reductase activity
N7980_09910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N7980_09915	COG2010	Cytochrome c
N7980_09915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N7980_09920	COG4347	Protein of unknown function (DUF1405)
N7980_09930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7980_09935	COG1694	Mazg nucleotide pyrophosphohydrolase
N7980_09940	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N7980_09945	COG1803	Methylglyoxal synthase
N7980_09950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N7980_09955	COG0438	transferase activity, transferring glycosyl groups
N7980_09960	COG0617	tRNA 3'-terminal CCA addition
N7980_09965	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
N7980_09965	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
N7980_09970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N7980_09975	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N7980_09980	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
N7980_09985	COG1199	ATP-dependent helicase activity
N7980_09985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N7980_09995	COG5353	protein conserved in bacteria
N7980_10000	COG0436	Aminotransferase
N7980_10005	COG0017	Asparaginyl-tRNA synthetase
N7980_10010	COG3935	DnaD domain protein
N7980_10015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N7980_10025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7980_10025	COG4499	WXG100 protein secretion system (Wss), protein YukC
N7980_10030	COG3331	DNA recombination
N7980_10065	COG0071	Belongs to the small heat shock protein (HSP20) family
N7980_10070	COG2190	(PTS) system
N7980_10075	COG1205	dead DEAH box helicase
N7980_10075	COG1111	helicase
N7980_10080	COG3359	exonuclease
N7980_10095	COG4474	Belongs to the UPF0398 family
N7980_10110	COG0116	Belongs to the methyltransferase superfamily
N7980_10125	COG1199	ATP-dependent helicase activity
N7980_10130	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_10135	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
N7980_10140	COG1609	Transcriptional regulator
N7980_10145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7980_10150	COG0800	Aldolase
N7980_10160	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N7980_10165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7980_10170	COG2233	PERMEase
N7980_10175	COG3424	synthase
N7980_10180	COG1755	Isoprenylcysteine carboxyl methyltransferase
N7980_10190	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N7980_10205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7980_10215	COG0328	RNA-DNA hybrid ribonuclease activity
N7980_10220	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N7980_10225	COG0328	RNA-DNA hybrid ribonuclease activity
N7980_10245	COG1278	Cold shock
N7980_10255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N7980_10260	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
N7980_10265	COG0386	Belongs to the glutathione peroxidase family
N7980_10270	COG1418	mRNA catabolic process
N7980_10275	COG1413	lyase activity
N7980_10280	COG0129	dihydroxy-acid dehydratase activity
N7980_10290	COG2136	Putative SAM-dependent methyltransferase
N7980_10290	COG2521	methyltransferase
N7980_10300	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N7980_10305	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7980_10310	COG0204	Acyl-transferase
N7980_10315	COG1272	protein, Hemolysin III
N7980_10320	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N7980_10325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7980_10335	COG1999	signal sequence binding
N7980_10340	COG2755	lipolytic protein G-D-S-L family
N7980_10345	COG4698	Protein conserved in bacteria
N7980_10355	COG0534	Mate efflux family protein
N7980_10360	COG1846	Transcriptional regulator
N7980_10365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7980_10370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7980_10375	COG1086	Polysaccharide biosynthesis protein
N7980_10380	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
N7980_10385	COG4641	Protein conserved in bacteria
N7980_10400	COG0463	Glycosyl transferase, family 2
N7980_10405	COG0456	acetyltransferase
N7980_10420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7980_10425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N7980_10430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7980_10435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7980_10440	COG0456	acetyltransferase
N7980_10445	COG1509	lysine 2,3-aminomutase activity
N7980_10455	COG4479	Belongs to the UPF0346 family
N7980_10475	COG0671	phosphoesterase, PA-phosphatase related
N7980_10490	COG0813	purine-nucleoside phosphorylase activity
N7980_10495	COG1876	peptidase activity
N7980_10505	COG2226	methyltransferase
N7980_10510	COG0793	Belongs to the peptidase S41A family
N7980_10510	COG3409	Peptidoglycan-binding domain 1 protein
N7980_10515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7980_10525	COG0346	lactoylglutathione lyase activity
N7980_10530	COG0400	carboxylic ester hydrolase activity
N7980_10535	COG0778	Nitroreductase
N7980_10540	COG1733	regulation of RNA biosynthetic process
N7980_10545	COG1942	4-Oxalocrotonate Tautomerase
N7980_10550	COG2610	gluconate transmembrane transporter activity
N7980_10565	COG2962	Rard protein
N7980_10575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N7980_10580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N7980_10585	COG1366	Belongs to the anti-sigma-factor antagonist family
N7980_10590	COG0534	Mate efflux family protein
N7980_10595	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N7980_10600	COG1819	glycosyl
N7980_10605	COG0791	NLP P60 protein
N7980_10605	COG1388	LysM domain
N7980_10610	COG2032	superoxide dismutase activity
N7980_10615	COG0714	Associated with various cellular activities
N7980_10620	COG4548	von Willebrand factor, type A
N7980_10625	COG0567	Dehydrogenase, E1 component
N7980_10630	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7980_10635	COG0385	Bile acid
N7980_10640	COG0733	neurotransmitter:sodium symporter activity
N7980_10645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N7980_10650	COG1657	PFAM Prenyltransferase squalene oxidase
N7980_10655	COG1012	belongs to the aldehyde dehydrogenase family
N7980_10680	COG0071	Belongs to the small heat shock protein (HSP20) family
N7980_10695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N7980_10700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7980_10710	COG0514	ATP-dependent DNA helicase (RecQ)
N7980_10715	COG1388	LysM domain
N7980_10715	COG3584	3D domain protein
N7980_10720	COG2197	response regulator
N7980_10725	COG4585	Histidine kinase
N7980_10730	COG3239	Fatty acid desaturase
N7980_10735	COG1619	proteins homologs of microcin C7 resistance protein MccF
N7980_10750	COG2322	membrane
N7980_10755	COG0741	lytic transglycosylase activity
N7980_10760	COG0640	Transcriptional regulator
N7980_10770	COG2378	regulation of single-species biofilm formation
N7980_10775	COG3708	Transcriptional regulator
N7980_10780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7980_10785	COG1309	transcriptional regulator
N7980_10790	COG0456	acetyltransferase
N7980_10795	COG2207	Transcriptional regulator
N7980_10795	COG0662	Cupin 2, conserved barrel domain protein
N7980_10800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7980_10805	COG1231	oxidoreductase activity
N7980_10810	COG4282	regulation of fungal-type cell wall biogenesis
N7980_10835	COG0457	Tetratricopeptide repeat
N7980_10890	COG2314	TM2 domain
N7980_10895	COG0726	polysaccharide deacetylase
N7980_10900	COG3848	Pyruvate phosphate dikinase
N7980_10900	COG0574	Belongs to the PEP-utilizing enzyme family
N7980_10920	COG2367	Beta-lactamase
N7980_10925	COG0693	protein deglycase activity
N7980_10935	COG0697	spore germination
N7980_10940	COG0583	DNA-binding transcription factor activity
N7980_10945	COG3739	integral membrane protein
N7980_10960	COG2720	vancomycin resistance protein
N7980_10985	COG2140	Oxalate decarboxylase
N7980_10995	COG2135	peptidase activity
N7980_11000	COG3866	Pectate lyase
N7980_11005	COG3619	membrane
N7980_11010	COG4305	rare lipoprotein A
N7980_11015	COG2368	4-hydroxyphenylacetate
N7980_11020	COG5278	phosphoserine phosphatase activity
N7980_11020	COG0840	transmembrane signaling receptor activity
N7980_11040	COG1609	Transcriptional regulator
N7980_11045	COG1082	Xylose isomerase domain protein TIM barrel
N7980_11050	COG0673	inositol 2-dehydrogenase activity
N7980_11055	COG2814	Major facilitator Superfamily
N7980_11065	COG0243	molybdopterin cofactor binding
N7980_11070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N7980_11075	COG1070	Carbohydrate kinase
N7980_11080	COG2814	Major facilitator Superfamily
N7980_11090	COG1131	(ABC) transporter
N7980_11105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7980_11115	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N7980_11120	COG0300	oxidoreductase activity
N7980_11130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7980_11135	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N7980_11140	COG0583	DNA-binding transcription factor activity
N7980_11145	COG0067	glutamate synthase
N7980_11145	COG0070	glutamate synthase
N7980_11145	COG0069	glutamate synthase activity
N7980_11150	COG0493	'glutamate synthase
N7980_11160	COG0583	DNA-binding transcription factor activity
N7980_11165	COG0405	Gamma-glutamyltransferase
N7980_11170	COG0166	Belongs to the GPI family
N7980_11175	COG0582	viral genome integration into host DNA
N7980_11190	COG0534	Mate efflux family protein
N7980_11195	COG2017	converts alpha-aldose to the beta-anomer
N7980_11200	COG2027	D-alanyl-D-alanine carboxypeptidase
N7980_11205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_11210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_11215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_11220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_11225	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N7980_11225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_11235	COG1649	PFAM Uncharacterised BCR, COG1649
N7980_11245	COG1960	acyl-CoA dehydrogenase activity
N7980_11250	COG0318	PFAM AMP-dependent synthetase and ligase
N7980_11255	COG0439	Biotin carboxylase
N7980_11260	COG0511	ligase activity, forming carbon-carbon bonds
N7980_11265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7980_11270	COG1024	Enoyl-CoA hydratase
N7980_11275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7980_11280	COG2404	hydrolase activity, acting on ester bonds
N7980_11285	COG0586	Pfam SNARE associated Golgi protein
N7980_11290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7980_11295	COG2246	polysaccharide biosynthetic process
N7980_11300	COG3507	Belongs to the glycosyl hydrolase 43 family
N7980_11305	COG5520	Belongs to the glycosyl hydrolase 30 family
N7980_11315	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
N7980_11320	COG1115	amino acid carrier protein
N7980_11335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7980_11340	COG0187	DNA topoisomerase II activity
N7980_11345	COG1832	CoA-binding protein
N7980_11350	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N7980_11355	COG4841	protein insertion into membrane
N7980_11365	COG0824	Thioesterase
N7980_11385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7980_11390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N7980_11405	COG0071	Belongs to the small heat shock protein (HSP20) family
N7980_11415	COG4846	Membrane protein involved in cytochrome C biogenesis
N7980_11420	COG2201	protein-glutamate methylesterase activity
N7980_11425	COG0785	Cytochrome C biogenesis protein
N7980_11435	COG3763	UPF0154 protein
N7980_11445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N7980_11450	COG4224	UPF0291 protein
N7980_11455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7980_11460	COG1388	LysM domain
N7980_11465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N7980_11475	COG0346	lactoylglutathione lyase activity
N7980_11485	COG4195	phage-related replication protein
N7980_11515	COG0531	amino acid
N7980_11520	COG0697	spore germination
N7980_11535	COG3832	glyoxalase III activity
N7980_11550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7980_11590	COG0756	dUTP diphosphatase activity
N7980_11605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N7980_11610	COG2814	Major facilitator Superfamily
N7980_11625	COG1070	Carbohydrate kinase
N7980_11630	COG2115	Belongs to the xylose isomerase family
N7980_11635	COG1940	carbohydrate kinase activity
N7980_11640	COG3507	Belongs to the glycosyl hydrolase 43 family
N7980_11645	COG2211	Major facilitator Superfamily
N7980_11650	COG0135	phosphoribosylanthranilate isomerase activity
N7980_11680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7980_11690	COG4282	regulation of fungal-type cell wall biogenesis
N7980_11715	COG0174	glutamine synthetase
N7980_11720	COG0789	Transcriptional regulator
N7980_11725	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
N7980_11730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N7980_11735	COG0464	growth
N7980_11740	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7980_11745	COG4112	unkown
N7980_11750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7980_11755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7980_11760	COG1780	Probably involved in ribonucleotide reductase function
N7980_11775	COG1923	regulation of RNA biosynthetic process
N7980_11780	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N7980_11795	COG2076	Multidrug Resistance protein
N7980_11800	COG2076	Multidrug Resistance protein
N7980_11805	COG1764	response to oxidative stress
N7980_11810	COG4195	phage-related replication protein
N7980_11820	COG1404	Belongs to the peptidase S8 family
N7980_11825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7980_11835	COG2124	cytochrome p450
N7980_11840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N7980_11840	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N7980_11840	COG3321	synthase
N7980_11840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7980_11845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_11845	COG3321	synthase
N7980_11845	COG4221	oxidoreductase activity
N7980_11845	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_11850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7980_11850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7980_11850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_11850	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_11850	COG3321	synthase
N7980_11855	COG3321	synthase
N7980_11855	COG0300	oxidoreductase activity
N7980_11855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7980_11855	COG4221	oxidoreductase activity
N7980_11860	COG0318	PFAM AMP-dependent synthetase and ligase
N7980_11860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_11860	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_11860	COG3321	synthase
N7980_11860	COG0300	oxidoreductase activity
N7980_11865	COG1024	Enoyl-CoA hydratase
N7980_11870	COG1024	Enoyl-CoA hydratase
N7980_11875	COG3425	synthase
N7980_11880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7980_11885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7980_11890	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N7980_11890	COG2070	2-Nitropropane dioxygenase
N7980_11895	COG3321	synthase
N7980_11900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N7980_11910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7980_11915	COG3226	Transcriptional regulator
N7980_11930	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N7980_11935	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N7980_11945	COG4550	Control of competence regulator ComK, YlbF/YmcA
N7980_11950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7980_11955	COG0156	8-amino-7-oxononanoate synthase activity
N7980_11960	COG1063	alcohol dehydrogenase
N7980_11965	COG2359	stage V sporulation protein S
N7980_11970	COG1692	metallophosphoesterase
N7980_11975	COG1418	mRNA catabolic process
N7980_11980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7980_11985	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N7980_11990	COG1546	Belongs to the CinA family
N7980_11990	COG1058	Belongs to the CinA family
N7980_11995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N7980_12000	COG1426	Protein conserved in bacteria
N7980_12015	COG0300	oxidoreductase activity
N7980_12020	COG0612	Peptidase, M16
N7980_12025	COG0612	Peptidase, M16
N7980_12030	COG2814	Major facilitator Superfamily
N7980_12035	COG2188	Transcriptional regulator
N7980_12040	COG4980	gas vesicle protein
N7980_12040	COG1674	ftsk spoiiie
N7980_12050	COG0740	serine-type endopeptidase activity
N7980_12055	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N7980_12060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7980_12065	COG0527	aspartate kinase activity
N7980_12070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N7980_12075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N7980_12080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7980_12085	COG1873	PFAM PRC-barrel domain
N7980_12090	COG0612	Peptidase, M16
N7980_12095	COG0726	polysaccharide deacetylase
N7980_12100	COG1185	polyribonucleotide nucleotidyltransferase activity
N7980_12105	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N7980_12110	COG0196	riboflavin kinase activity
N7980_12115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N7980_12120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N7980_12125	COG1550	Protein conserved in bacteria
N7980_12130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N7980_12135	COG1358	cellular component organization or biogenesis
N7980_12140	COG2740	Nucleic-acid-binding protein implicated in transcription termination
N7980_12145	COG0195	Participates in both transcription termination and antitermination
N7980_12150	COG0779	Required for maturation of 30S ribosomal subunits
N7980_12175	COG2176	DNA-directed DNA polymerase activity
N7980_12180	COG0442	prolyl-tRNA aminoacylation
N7980_12185	COG0750	zinc metalloprotease
N7980_12190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N7980_12195	COG4589	Belongs to the CDS family
N7980_12200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N7980_12205	COG0233	cytoplasmic translational termination
N7980_12210	COG0528	UMP kinase activity
N7980_12215	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N7980_12220	COG0052	Belongs to the universal ribosomal protein uS2 family
N7980_12230	COG1191	sigma factor activity
N7980_12235	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N7980_12240	COG1776	CheC inhibitor of MCP methylation
N7980_12245	COG0835	chemotaxis
N7980_12250	COG0643	Histidine kinase
N7980_12250	COG2198	Histidine kinase
N7980_12255	COG2201	protein-glutamate methylesterase activity
N7980_12260	COG0455	bacterial-type flagellum organization
N7980_12265	COG1419	protein localization to endoplasmic reticulum
N7980_12270	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N7980_12275	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N7980_12280	COG1684	flagellar biosynthetic protein fliR
N7980_12285	COG1987	bacterial-type flagellum assembly
N7980_12290	COG1338	Plays a role in the flagellum-specific transport system
N7980_12295	COG3190	flagellar
N7980_12300	COG2201	protein-glutamate methylesterase activity
N7980_12305	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7980_12305	COG1776	CheC inhibitor of MCP methylation
N7980_12310	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7980_12315	COG1580	Controls the rotational direction of flagella during chemotaxis
N7980_12320	COG1582	Flagellar protein (FlbD)
N7980_12325	COG4786	Flagellar basal body rod
N7980_12330	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N7980_12335	COG3144	bacterial-type flagellum assembly
N7980_12340	COG3334	PFAM MgtE intracellular
N7980_12345	COG2882	bacterial-type flagellum organization
N7980_12350	COG1157	protein secretion by the type III secretion system
N7980_12355	COG1317	bacterial-type flagellum organization
N7980_12360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7980_12365	COG1766	The M ring may be actively involved in energy transduction
N7980_12370	COG1677	Flagellar hook-basal body complex protein FliE
N7980_12375	COG1558	bacterial-type flagellum-dependent cell motility
N7980_12380	COG1815	bacterial-type flagellum-dependent cell motility
N7980_12385	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N7980_12390	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N7980_12395	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N7980_12400	COG4974	Belongs to the 'phage' integrase family
N7980_12405	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
N7980_12410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N7980_12415	COG0758	DNA mediated transformation
N7980_12420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N7980_12425	COG0045	succinate-CoA ligase (ADP-forming) activity
N7980_12430	COG2257	FlhB HrpN YscU SpaS Family
N7980_12440	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N7980_12445	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N7980_12450	COG0335	large ribosomal subunit rRNA binding
N7980_12455	COG0336	Belongs to the RNA methyltransferase TrmD family
N7980_12460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N7980_12470	COG1837	Belongs to the UPF0109 family
N7980_12475	COG0228	four-way junction DNA binding
N7980_12480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N7980_12485	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
N7980_12495	COG0552	protein localization to endoplasmic reticulum
N7980_12500	COG1196	nuclear chromosome segregation
N7980_12505	COG0571	ribonuclease III activity
N7980_12515	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_12520	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N7980_12525	COG0416	fatty acid biosynthetic process
N7980_12530	COG2050	protein possibly involved in aromatic compounds catabolism
N7980_12530	COG1349	DNA-binding transcription factor activity
N7980_12535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N7980_12540	COG1760	l-serine dehydratase
N7980_12545	COG1760	l-serine dehydratase
N7980_12550	COG1461	Dihydroxyacetone kinase
N7980_12555	COG1302	Protein conserved in bacteria
N7980_12560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N7980_12570	COG1564	THIamine pyrophosphokinase
N7980_12575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N7980_12580	COG1162	GTPase activity
N7980_12585	COG0515	serine threonine protein kinase
N7980_12585	COG2815	serine threonine protein kinase
N7980_12590	COG0631	protein serine/threonine phosphatase activity
N7980_12595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N7980_12600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7980_12600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N7980_12605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N7980_12610	COG0242	peptide deformylase activity
N7980_12615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N7980_12620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N7980_12625	COG1758	RNA polymerase activity
N7980_12630	COG0194	GDP metabolic process
N7980_12640	COG1561	YicC-like family, N-terminal region
N7980_12645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N7980_12650	COG1293	RNA-binding protein homologous to eukaryotic snRNP
N7980_12655	COG1648	precorrin-2 dehydrogenase activity
N7980_12660	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
N7980_12665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N7980_12670	COG0529	Catalyzes the synthesis of activated sulfate
N7980_12675	COG2046	Belongs to the sulfate adenylyltransferase family
N7980_12680	COG0306	phosphate transporter
N7980_12685	COG0175	sulfate reduction
N7980_12690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N7980_12695	COG0284	orotidine-5'-phosphate decarboxylase activity
N7980_12700	COG0167	dihydroorotate dehydrogenase activity
N7980_12705	COG0543	2 iron, 2 sulfur cluster binding
N7980_12710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N7980_12715	COG0505	Belongs to the CarA family
N7980_12720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N7980_12725	COG0540	Belongs to the ATCase OTCase family
N7980_12730	COG2233	PERMEase
N7980_12735	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
N7980_12740	COG0564	pseudouridine synthase activity
N7980_12745	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N7980_12750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N7980_12755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N7980_12760	COG3599	regulation of cell shape
N7980_12765	COG2302	S4 RNA-binding domain
N7980_12770	COG0762	integral membrane protein
N7980_12775	COG1799	cell septum assembly
N7980_12780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N7980_12785	COG1496	oxidoreductase activity
N7980_12790	COG1873	PFAM PRC-barrel domain
N7980_12795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7980_12800	COG1119	ATPase activity
N7980_12805	COG1191	sigma factor activity
N7980_12810	COG1191	sigma factor activity
N7980_12820	COG4412	M6 family metalloprotease domain protein
N7980_12820	COG1404	Belongs to the peptidase S8 family
N7980_12825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N7980_12830	COG0849	cell division
N7980_12835	COG3856	small basic protein
N7980_12840	COG3879	Bacterial protein of unknown function (DUF881)
N7980_12845	COG3879	Bacterial protein of unknown function (DUF881)
N7980_12850	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N7980_12855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N7980_12860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N7980_12865	COG0772	Belongs to the SEDS family
N7980_12870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N7980_12875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N7980_12880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N7980_12885	COG0768	penicillin binding
N7980_12890	COG0768	penicillin binding
N7980_12895	COG4839	cell division protein FtsL
N7980_12900	COG0275	rRNA processing
N7980_12905	COG2001	Belongs to the MraZ family
N7980_12910	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
N7980_12915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N7980_12920	COG0454	-acetyltransferase
N7980_12935	COG1399	metal-binding, possibly nucleic acid-binding protein
N7980_12945	COG1323	Belongs to the UPF0348 family
N7980_12950	COG3480	Lon protease (S16) C-terminal proteolytic domain
N7980_12955	COG1752	Esterase of the alpha-beta hydrolase superfamily
N7980_12960	COG3314	Sporulation integral membrane protein YlbJ
N7980_12965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N7980_12970	COG0742	ribosomal rna small subunit methyltransferase
N7980_12975	COG4471	UPF0298 protein
N7980_12980	COG3679	Belongs to the UPF0342 family
N7980_12995	COG2340	Cysteine-rich secretory protein family
N7980_13000	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
N7980_13010	COG3336	cytochrome c oxidase
N7980_13015	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N7980_13020	COG1845	cytochrome c oxidase, subunit III
N7980_13025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7980_13030	COG2010	Cytochrome c
N7980_13030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7980_13035	COG0109	protoheme IX farnesyltransferase activity
N7980_13040	COG1612	heme a metabolic process
N7980_13045	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N7980_13050	COG0772	Belongs to the SEDS family
N7980_13055	COG4838	Belongs to the UPF0358 family
N7980_13060	COG2066	Belongs to the glutaminase family
N7980_13065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N7980_13070	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N7980_13080	COG4896	Protein conserved in bacteria
N7980_13090	COG1217	gtp-binding protein TYPA
N7980_13130	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
N7980_13140	COG0483	inositol monophosphate 1-phosphatase activity
N7980_13150	COG4493	Belongs to the UPF0637 family
N7980_13155	COG4476	Belongs to the UPF0223 family
N7980_13160	COG1982	Orn Lys Arg decarboxylase major
N7980_13170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7980_13175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7980_13180	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7980_13185	COG0022	dehydrogenase e1 component
N7980_13190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7980_13195	COG0497	DNA recombination
N7980_13205	COG0242	peptide deformylase activity
N7980_13210	COG0561	phosphatase activity
N7980_13215	COG5503	Protein of unknown function (DUF1447)
N7980_13220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N7980_13225	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7980_13230	COG0569	domain protein
N7980_13235	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
N7980_13235	COG2105	PFAM AIG2 family protein
N7980_13240	COG3852	Histidine kinase
N7980_13245	COG2002	toxin-antitoxin pair type II binding
N7980_13250	COG1077	Cell shape determining protein MreB Mrl
N7980_13260	COG2309	aminopeptidase activity
N7980_13265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N7980_13270	COG0488	(ABC) transporter
N7980_13280	COG0681	Belongs to the peptidase S26 family
N7980_13285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7980_13285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7980_13285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7980_13290	COG1105	Belongs to the carbohydrate kinase PfkB family
N7980_13295	COG1349	DNA-binding transcription factor activity
N7980_13300	COG0577	efflux transmembrane transporter activity
N7980_13305	COG1136	(ABC) transporter
N7980_13310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7980_13320	COG1132	(ABC) transporter
N7980_13325	COG1132	(ABC) transporter
N7980_13330	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N7980_13335	COG0314	molybdopterin synthase activity
N7980_13340	COG1763	Mo-molybdopterin cofactor biosynthetic process
N7980_13345	COG0303	'Molybdopterin
N7980_13350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N7980_13355	COG0746	molybdenum cofactor guanylyltransferase activity
N7980_13370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7980_13375	COG0450	alkyl hydroperoxide reductase
N7980_13380	COG0668	transmembrane transport
N7980_13390	COG1473	amidohydrolase
N7980_13395	COG2171	N-acyltransferase activity
N7980_13400	COG0716	FMN binding
N7980_13410	COG0716	FMN binding
N7980_13415	COG0583	DNA-binding transcription factor activity
N7980_13420	COG0517	IMP dehydrogenase activity
N7980_13430	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
N7980_13435	COG4703	Protein of unknown function (DUF1797)
N7980_13440	COG2200	EAL domain
N7980_13445	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_13450	COG1408	metallophosphoesterase
N7980_13455	COG1376	ErfK ybiS ycfS ynhG family protein
N7980_13460	COG2814	Major facilitator Superfamily
N7980_13470	COG0835	chemotaxis
N7980_13470	COG0784	Response regulator, receiver
N7980_13480	COG0436	Aminotransferase
N7980_13485	COG4191	Histidine kinase
N7980_13490	COG0768	penicillin binding
N7980_13495	COG2340	Cysteine-rich secretory protein family
N7980_13500	COG4257	antibiotic catabolic process
N7980_13505	COG2084	Dehydrogenase
N7980_13510	COG0840	transmembrane signaling receptor activity
N7980_13515	COG0456	acetyltransferase
N7980_13520	COG1533	DNA photolyase activity
N7980_13530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N7980_13535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7980_13540	COG1263	PTS System
N7980_13540	COG2190	(PTS) system
N7980_13540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_13545	COG3711	transcriptional antiterminator
N7980_13550	COG1609	Transcriptional regulator
N7980_13555	COG0006	proline dipeptidase activity
N7980_13565	COG2217	Heavy metal translocating P-type atpase
N7980_13570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7980_13575	COG2244	polysaccharide biosynthetic process
N7980_13580	COG3773	Cell wall hydrolase
N7980_13590	COG4873	Protein conserved in bacteria
N7980_13600	COG3858	chitin binding
N7980_13605	COG3858	chitin binding
N7980_13610	COG1388	LysM domain
N7980_13615	COG1388	LysM domain
N7980_13615	COG4641	Protein conserved in bacteria
N7980_13620	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_13625	COG1733	regulation of RNA biosynthetic process
N7980_13630	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N7980_13635	COG0602	queuosine metabolic process
N7980_13640	COG0720	synthase
N7980_13645	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N7980_13650	COG3949	Membrane
N7980_13655	COG0542	response to heat
N7980_13660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N7980_13665	COG1360	Flagellar Motor Protein
N7980_13670	COG1846	Transcriptional regulator
N7980_13675	COG3852	Histidine kinase
N7980_13690	COG3339	Conserved Protein
N7980_13695	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
N7980_13700	COG0235	Class ii aldolase
N7980_13705	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
N7980_13710	COG1850	ribulose-bisphosphate carboxylase activity
N7980_13715	COG0436	Aminotransferase
N7980_13720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N7980_13725	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
N7980_13730	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N7980_13740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7980_13745	COG5002	protein histidine kinase activity
N7980_13750	COG3594	Acyltransferase
N7980_13765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N7980_13770	COG0501	Belongs to the peptidase M48B family
N7980_13790	COG1191	sigma factor activity
N7980_13795	COG0861	Integral membrane protein TerC family
N7980_13800	COG0586	Pfam SNARE associated Golgi protein
N7980_13805	COG5001	Diguanylate cyclase
N7980_13805	COG3300	MHYT domain
N7980_13810	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
N7980_13815	COG1793	dna ligase
N7980_13815	COG3285	dna ligase
N7980_13820	COG0463	Glycosyl transferase, family 2
N7980_13830	COG1408	metallophosphoesterase
N7980_13835	COG0726	polysaccharide deacetylase
N7980_13840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N7980_13845	COG1846	Transcriptional regulator
N7980_13860	COG0789	Transcriptional regulator
N7980_13865	COG2239	Acts as a magnesium transporter
N7980_13880	COG3212	peptidase
N7980_13885	COG3212	peptidase
N7980_13890	COG5002	protein histidine kinase activity
N7980_13890	COG3850	Histidine kinase
N7980_13895	COG0745	RESPONSE REGULATOR receiver
N7980_13905	COG4721	ABC-type cobalt transport system, permease component
N7980_13910	COG1122	ATPase activity
N7980_13915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N7980_13920	COG1366	Belongs to the anti-sigma-factor antagonist family
N7980_13925	COG1404	Belongs to the peptidase S8 family
N7980_13930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N7980_13935	COG0590	tRNA wobble adenosine to inosine editing
N7980_13945	COG1764	response to oxidative stress
N7980_13950	COG1846	Transcriptional regulator
N7980_13955	COG1764	response to oxidative stress
N7980_13960	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N7980_13965	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N7980_13970	COG0788	formyltetrahydrofolate deformylase activity
N7980_13975	COG2076	Multidrug Resistance protein
N7980_13980	COG2076	Multidrug Resistance protein
N7980_13985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7980_13990	COG2318	DinB family
N7980_13995	COG2323	membrane
N7980_14005	COG1017	nitric oxide dioxygenase activity
N7980_14005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7980_14010	COG1607	acyl-coa hydrolase
N7980_14015	COG1834	amidinotransferase
N7980_14020	COG2706	6-phosphogluconolactonase activity
N7980_14025	COG4608	Belongs to the ABC transporter superfamily
N7980_14030	COG0791	NLP P60 protein
N7980_14035	COG4948	Mandelate Racemase Muconate Lactonizing
N7980_14040	COG1619	proteins homologs of microcin C7 resistance protein MccF
N7980_14045	COG4166	transmembrane transport
N7980_14050	COG0444	Belongs to the ABC transporter superfamily
N7980_14055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7980_14060	COG0601	transmembrane transport
N7980_14065	COG2362	D-Aminopeptidase
N7980_14070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7980_14075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7980_14085	COG0463	Glycosyl transferase, family 2
N7980_14090	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N7980_14100	COG0346	lactoylglutathione lyase activity
N7980_14105	COG0531	amino acid
N7980_14110	COG1392	Phosphate transport regulator
N7980_14115	COG0306	phosphate transporter
N7980_14135	COG5632	N-Acetylmuramoyl-L-alanine amidase
N7980_14135	COG3409	Peptidoglycan-binding domain 1 protein
N7980_14175	COG3778	Protein conserved in bacteria
N7980_14180	COG3299	homolog of phage Mu protein gp47
N7980_14185	COG3628	GPW Gp25 family protein
N7980_14195	COG4193	domain, Protein
N7980_14200	COG1652	LysM domain
N7980_14205	COG3953	SLT domain
N7980_14205	COG5412	phage tail tape measure protein
N7980_14255	COG4653	Phage capsid family
N7980_14260	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N7980_14265	COG5518	Phage portal protein
N7980_14270	COG1783	phage Terminase large subunit
N7980_14275	COG3728	DNA packaging
N7980_14275	COG5484	DNA packaging
N7980_14280	COG1595	DNA-templated transcription, initiation
N7980_14300	COG1484	DNA-dependent DNA replication
N7980_14305	COG1522	sequence-specific DNA binding
N7980_14315	COG1396	sequence-specific DNA binding
N7980_14320	COG2856	Zn peptidase
N7980_14325	COG3546	catalase activity
N7980_14330	COG4195	phage-related replication protein
N7980_14340	COG5632	N-Acetylmuramoyl-L-alanine amidase
N7980_14340	COG3409	Peptidoglycan-binding domain 1 protein
N7980_14340	COG1388	LysM domain
N7980_14345	COG2350	Protein conserved in bacteria
N7980_14355	COG0457	Tetratricopeptide repeat
N7980_14360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N7980_14365	COG2318	DinB family
N7980_14370	COG0730	response to heat
N7980_14375	COG2721	sulfolactate sulfo-lyase activity
N7980_14380	COG0246	Mannitol dehydrogenase
N7980_14385	COG1609	Transcriptional regulator
N7980_14390	COG2271	Major facilitator Superfamily
N7980_14395	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_14400	COG1312	Catalyzes the dehydration of D-mannonate
N7980_14405	COG1063	alcohol dehydrogenase
N7980_14410	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N7980_14415	COG2211	Major facilitator Superfamily
N7980_14420	COG1904	glucuronate isomerase
N7980_14425	COG1252	NADH dehydrogenase
N7980_14435	COG4297	protein containing double-stranded beta helix domain
N7980_14440	COG0697	spore germination
N7980_14445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7980_14450	COG0390	transport system, permease component
N7980_14455	COG1587	Uroporphyrinogen-III synthase
N7980_14475	COG1819	glycosyl
N7980_14480	COG2124	cytochrome p450
N7980_14490	COG1051	belongs to the nudix hydrolase family
N7980_14500	COG2427	Protein of unknown function (DUF1641)
N7980_14505	COG3383	formate dehydrogenase (NAD+) activity
N7980_14515	COG2205	protein histidine kinase activity
N7980_14520	COG5504	Zn-dependent protease
N7980_14535	COG0726	polysaccharide deacetylase
N7980_14545	COG0109	protoheme IX farnesyltransferase activity
N7980_14560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N7980_14570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7980_14580	COG1482	cell wall glycoprotein biosynthetic process
N7980_14585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7980_14585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7980_14585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7980_14590	COG3711	transcriptional antiterminator
N7980_14590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7980_14600	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_14605	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N7980_14655	COG5444	nuclease activity
N7980_14670	COG5505	Protein of unknown function (DUF819)
N7980_14675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7980_14680	COG0626	cystathionine gamma-synthase activity
N7980_14685	COG0626	cystathionine gamma-synthase activity
N7980_14690	COG2382	esterase
N7980_14695	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N7980_14700	COG2153	protein acetylation
N7980_14710	COG0210	DNA helicase
N7980_14765	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N7980_14770	COG0351	phosphomethylpyrimidine kinase
N7980_14775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N7980_14780	COG2022	thiamine diphosphate biosynthetic process
N7980_14785	COG2104	thiamine diphosphate biosynthetic process
N7980_14790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7980_14795	COG0352	thiamine-phosphate diphosphorylase activity
N7980_14800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N7980_14805	COG0569	domain protein
N7980_14805	COG0475	glutathione-regulated potassium exporter activity
N7980_14810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N7980_14815	COG0564	pseudouridine synthase activity
N7980_14820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N7980_14825	COG2357	RelA SpoT domain protein
N7980_14835	COG4116	CYTH
N7980_14840	COG0741	lytic transglycosylase activity
N7980_14845	COG2346	COG2346, Truncated hemoglobins
N7980_14850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N7980_14860	COG1164	Oligoendopeptidase f
N7980_14865	COG4469	Competence protein
N7980_14875	COG4862	establishment of competence for transformation
N7980_14885	COG0861	Integral membrane protein TerC family
N7980_14890	COG1393	Belongs to the ArsC family
N7980_14895	COG0456	acetyltransferase
N7980_14900	COG2814	Major facilitator Superfamily
N7980_14905	COG4608	Belongs to the ABC transporter superfamily
N7980_14910	COG0444	Belongs to the ABC transporter superfamily
N7980_14915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7980_14920	COG0601	transmembrane transport
N7980_14925	COG4166	transmembrane transport
N7980_14930	COG0180	Tryptophanyl-tRNA synthetase
N7980_14940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7980_14945	COG0601	transmembrane transport
N7980_14955	COG4608	Belongs to the ABC transporter superfamily
N7980_14960	COG0444	Belongs to the ABC transporter superfamily
N7980_14965	COG5504	Zn-dependent protease
N7980_14970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7980_14975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7980_14990	COG1744	ABC transporter substrate-binding protein PnrA-like
N7980_15000	COG2267	carboxylic ester hydrolase activity
N7980_15015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N7980_15020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N7980_15025	COG0505	Belongs to the CarA family
N7980_15030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N7980_15040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N7980_15045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N7980_15050	COG2271	Major facilitator Superfamily
N7980_15055	COG0277	FAD linked oxidase domain protein
N7980_15065	COG2151	metal-sulfur cluster biosynthetic enzyme
N7980_15070	COG1073	alpha beta
N7980_15075	COG0561	phosphatase activity
N7980_15095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7980_15100	COG1307	EDD domain protein, DegV family
N7980_15105	COG3227	Zinc metalloprotease (Elastase)
N7980_15120	COG1695	Transcriptional regulator
N7980_15145	COG1666	GTP binding
N7980_15150	COG0646	methionine synthase
N7980_15150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N7980_15155	COG2153	protein acetylation
N7980_15160	COG0454	-acetyltransferase
N7980_15165	COG2814	Major facilitator Superfamily
N7980_15170	COG4948	Mandelate Racemase Muconate Lactonizing
N7980_15175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7980_15180	COG1809	phosphosulfolactate synthase activity
N7980_15185	COG2045	Belongs to the ComB family
N7980_15190	COG0175	sulfate reduction
N7980_15195	COG2046	Belongs to the sulfate adenylyltransferase family
N7980_15200	COG0529	Catalyzes the synthesis of activated sulfate
N7980_15205	COG2267	carboxylic ester hydrolase activity
N7980_15210	COG1357	PFAM Pentapeptide repeats (8 copies)
N7980_15215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7980_15220	COG1279	arginine transmembrane transporter activity
N7980_15225	COG2318	DinB family
N7980_15230	COG0673	inositol 2-dehydrogenase activity
N7980_15235	COG1609	Transcriptional regulator
N7980_15240	COG1917	Cupin 2, conserved barrel domain protein
N7980_15240	COG2207	Transcriptional regulator
N7980_15245	COG0534	Mate efflux family protein
N7980_15255	COG2318	DinB family
N7980_15260	COG0367	asparagine synthase
N7980_15270	COG1404	Belongs to the peptidase S8 family
N7980_15280	COG0179	Fumarylacetoacetate (FAA) hydrolase
N7980_15285	COG5337	Spore coat protein CotH
N7980_15325	COG1403	HNH endonuclease
N7980_15330	COG0419	ATPase involved in DNA repair
N7980_15335	COG0420	3'-5' exonuclease activity
N7980_15340	COG1074	ATP-dependent DNA helicase activity
N7980_15345	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
N7980_15350	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
N7980_15360	COG4533	DNA binding
N7980_15365	COG2814	Major facilitator Superfamily
N7980_15365	COG0477	Major facilitator Superfamily
N7980_15370	COG3180	Ammonia monooxygenase
N7980_15375	COG1609	Transcriptional regulator
N7980_15380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N7980_15385	COG0561	phosphatase activity
N7980_15390	COG0673	inositol 2-dehydrogenase activity
N7980_15395	COG0738	Major facilitator superfamily
N7980_15405	COG1846	Transcriptional regulator
N7980_15410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7980_15415	COG0681	Belongs to the peptidase S26 family
N7980_15420	COG0398	Pfam SNARE associated Golgi protein
N7980_15435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7980_15445	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_15450	COG4903	ComK protein
N7980_15460	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_15465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7980_15465	COG0723	plastoquinol--plastocyanin reductase activity
N7980_15470	COG0840	transmembrane signaling receptor activity
N7980_15475	COG1268	BioY protein
N7980_15480	COG0318	PFAM AMP-dependent synthetase and ligase
N7980_15485	COG0183	Belongs to the thiolase family
N7980_15490	COG0406	alpha-ribazole phosphatase activity
N7980_15495	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
N7980_15500	COG0604	alcohol dehydrogenase
N7980_15505	COG0456	acetyltransferase
N7980_15515	COG0501	Belongs to the peptidase M48B family
N7980_15525	COG0318	PFAM AMP-dependent synthetase and ligase
N7980_15530	COG0702	epimerase
N7980_15535	COG0095	Lipoate-protein ligase
N7980_15540	COG1234	tRNA 3'-trailer cleavage
N7980_15550	COG1301	dicarboxylic acid transport
N7980_15555	COG4405	Protein conserved in bacteria
N7980_15560	COG1363	Peptidase, m42
N7980_15570	COG4377	Putative membrane peptidase family (DUF2324)
N7980_15575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7980_15580	COG1511	domain protein
N7980_15585	COG1309	transcriptional regulator
N7980_15590	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
N7980_15595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N7980_15600	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N7980_15605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7980_15610	COG2329	Antibiotic biosynthesis monooxygenase
N7980_15620	COG3069	C4-dicarboxylate transmembrane transporter activity
N7980_15625	COG1473	amidohydrolase
N7980_15635	COG4473	ABC transporter
N7980_15640	COG1131	(ABC) transporter
N7980_15645	COG0537	adenosine 5'-monophosphoramidase activity
N7980_15650	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N7980_15665	COG4980	gas vesicle protein
N7980_15670	COG1846	Transcriptional regulator
N7980_15700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N7980_15710	COG3481	metal-dependent phosphohydrolase, HD sub domain
N7980_15715	COG4717	serine-type aminopeptidase activity
N7980_15720	COG0420	3'-5' exonuclease activity
N7980_15725	COG1668	transmembrane transport
N7980_15730	COG4152	abc transporter atp-binding protein
N7980_15740	COG1024	Enoyl-CoA hydratase
N7980_15750	COG0490	domain, Protein
N7980_15755	COG0475	glutathione-regulated potassium exporter activity
N7980_15760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7980_15765	COG0561	phosphatase activity
N7980_15770	COG4335	DNA alkylation repair
N7980_15775	COG3679	Belongs to the UPF0342 family
N7980_15780	COG4399	Belongs to the UPF0754 family
N7980_15785	COG0189	ligase activity
N7980_15790	COG0189	ligase activity
N7980_15810	COG0702	epimerase
N7980_15815	COG1132	(ABC) transporter
N7980_15820	COG1132	(ABC) transporter
N7980_15830	COG0589	response to stress
N7980_15835	COG1757	Na H antiporter
N7980_15840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7980_15845	COG0726	polysaccharide deacetylase
N7980_15850	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N7980_15855	COG0668	transmembrane transport
N7980_15865	COG0584	glycerophosphoryl diester phosphodiesterase
N7980_15870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N7980_15875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N7980_15880	COG1253	flavin adenine dinucleotide binding
N7980_15885	COG0436	Aminotransferase
N7980_15890	COG0789	Transcriptional regulator
N7980_15895	COG1253	flavin adenine dinucleotide binding
N7980_15900	COG0204	Acyl-transferase
N7980_15905	COG0667	Aldo Keto reductase
N7980_15910	COG1595	DNA-templated transcription, initiation
N7980_15925	COG0456	acetyltransferase
N7980_15930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7980_15935	COG0733	neurotransmitter:sodium symporter activity
N7980_15940	COG0531	amino acid
N7980_15945	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_15950	COG0372	Belongs to the citrate synthase family
N7980_15955	COG0583	DNA-binding transcription factor activity
N7980_15960	COG1388	LysM domain
N7980_15960	COG0791	NLP P60 protein
N7980_15965	COG1785	Belongs to the alkaline phosphatase family
N7980_15970	COG2719	SpoVR family
N7980_15975	COG0668	transmembrane transport
N7980_15980	COG1959	2 iron, 2 sulfur cluster binding
N7980_15985	COG1388	LysM domain
N7980_15985	COG0791	NLP P60 protein
N7980_16000	COG0431	NADPH-dependent FMN reductase
N7980_16005	COG2197	response regulator
N7980_16010	COG2203	Gaf domain
N7980_16010	COG4585	Histidine kinase
N7980_16015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7980_16020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N7980_16025	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N7980_16030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N7980_16035	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
N7980_16040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7980_16045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N7980_16045	COG3153	acetyltransferase
N7980_16050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7980_16055	COG0517	IMP dehydrogenase activity
N7980_16065	COG0564	pseudouridine synthase activity
N7980_16070	COG3764	Sortase (surface protein transpeptidase)
N7980_16075	COG4085	toxin activity
N7980_16075	COG1525	nuclease
N7980_16075	COG0737	Belongs to the 5'-nucleotidase family
N7980_16080	COG5577	PFAM Coat F domain
N7980_16110	COG1823	symporter activity
N7980_16115	COG3706	GGDEF domain
N7980_16120	COG1464	Belongs to the NlpA lipoprotein family
N7980_16125	COG1278	Cold shock
N7980_16130	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N7980_16135	COG1131	(ABC) transporter
N7980_16140	COG1131	(ABC) transporter
N7980_16145	COG1725	Transcriptional regulator
N7980_16165	COG0655	NAD(P)H dehydrogenase (quinone) activity
N7980_16170	COG2814	Major facilitator Superfamily
N7980_16175	COG1566	PFAM secretion protein HlyD family protein
N7980_16180	COG1846	Transcriptional regulator
N7980_16185	COG2718	Belongs to the UPF0229 family
N7980_16190	COG2766	serine protein kinase
N7980_16195	COG1664	Polymer-forming cytoskeletal
N7980_16200	COG1664	Polymer-forming cytoskeletal
N7980_16205	COG0789	Transcriptional regulator
N7980_16210	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N7980_16220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N7980_16225	COG3382	B3 4 domain protein
N7980_16235	COG1476	TRANSCRIPTIONal
N7980_16245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N7980_16255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7980_16260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7980_16265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7980_16270	COG1116	anion transmembrane transporter activity
N7980_16275	COG0753	catalase activity
N7980_16290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N7980_16300	COG5577	PFAM Coat F domain
N7980_16310	COG4326	sporulation control protein
N7980_16420	COG0735	belongs to the Fur family
N7980_16425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N7980_16430	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N7980_16435	COG4129	membrane
N7980_16440	COG1132	(ABC) transporter
N7980_16445	COG3557	Belongs to the UPF0374 family
N7980_16460	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_16470	COG1194	a g-specific adenine glycosylase
N7980_16475	COG1988	membrane-bound metal-dependent
N7980_16480	COG4485	Bacterial membrane protein, YfhO
N7980_16485	COG0463	Glycosyl transferase, family 2
N7980_16490	COG0596	Alpha beta hydrolase
N7980_16495	COG5658	integral membrane protein
N7980_16500	COG3103	Sh3 type 3 domain protein
N7980_16515	COG2814	Major facilitator Superfamily
N7980_16525	COG2137	regulation of response to DNA damage stimulus
N7980_16530	COG1090	epimerase
N7980_16545	COG0778	Nitroreductase
N7980_16550	COG0384	phenazine biosynthesis protein PhzF
N7980_16555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7980_16560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7980_16565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7980_16570	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N7980_16570	COG0392	lysyltransferase activity
N7980_16575	COG1846	Transcriptional regulator
N7980_16580	COG2814	Major facilitator Superfamily
N7980_16585	COG2318	DinB family
N7980_16590	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
N7980_16595	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N7980_16600	COG1695	Transcriptional regulator
N7980_16605	COG0842	Transport permease protein
N7980_16610	COG0842	Transport permease protein
N7980_16610	COG1511	domain protein
N7980_16615	COG1131	(ABC) transporter
N7980_16620	COG2197	response regulator
N7980_16625	COG4585	Histidine kinase
N7980_16630	COG2514	catechol 2,3-dioxygenase activity
N7980_16635	COG2259	Doxx family
N7980_16640	COG1132	(ABC) transporter
N7980_16645	COG1132	(ABC) transporter
N7980_16650	COG5434	Belongs to the glycosyl hydrolase 28 family
N7980_16655	COG1263	PTS System
N7980_16655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_16660	COG1737	Transcriptional regulator
N7980_16665	COG1486	melibiose metabolic process
N7980_16670	COG4842	Belongs to the WXG100 family
N7980_16695	COG1742	UPF0060 membrane protein
N7980_16705	COG3284	Transcriptional regulator
N7980_16710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7980_16715	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7980_16720	COG0022	dehydrogenase e1 component
N7980_16725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7980_16735	COG4637	Psort location Cytoplasmic, score
N7980_16740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N7980_16750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N7980_16755	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N7980_16760	COG0598	Magnesium transport protein CorA
N7980_16765	COG2084	Dehydrogenase
N7980_16770	COG0726	polysaccharide deacetylase
N7980_16780	COG0535	radical SAM domain protein
N7980_16785	COG0668	transmembrane transport
N7980_16795	COG0387	Pfam Sodium calcium exchanger
N7980_16800	COG0477	Major facilitator Superfamily
N7980_16805	COG1295	ribonuclease BN
N7980_16810	COG4980	gas vesicle protein
N7980_16815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7980_16820	COG4840	Belongs to the UPF0435 family
N7980_16825	COG2814	Major facilitator Superfamily
N7980_16830	COG0693	protein deglycase activity
N7980_16835	COG0737	Belongs to the 5'-nucleotidase family
N7980_16840	COG0778	Nitroreductase
N7980_16845	COG2188	Transcriptional regulator
N7980_16850	COG0366	Alpha amylase catalytic
N7980_16855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_16855	COG1263	PTS System
N7980_16860	COG0697	spore germination
N7980_16875	COG0531	amino acid
N7980_16880	COG1115	amino acid carrier protein
N7980_16895	COG1368	sulfuric ester hydrolase activity
N7980_16900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_16900	COG1263	PTS System
N7980_16905	COG0024	Methionine aminopeptidase
N7980_16925	COG2258	MOSC domain
N7980_16930	COG1254	Belongs to the acylphosphatase family
N7980_16935	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
N7980_16940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7980_16945	COG2851	Citrate transporter
N7980_16955	COG3181	Tripartite tricarboxylate transporter family receptor
N7980_16960	COG4565	transcriptional regulatory protein
N7980_16965	COG3290	protein histidine kinase activity
N7980_16970	COG0471	metal ion transport
N7980_16975	COG3866	Pectate lyase
N7980_16990	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
N7980_16995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7980_17000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7980_17005	COG1120	ATPase activity
N7980_17010	COG2130	NADP-dependent
N7980_17015	COG0456	acetyltransferase
N7980_17020	COG0513	Belongs to the DEAD box helicase family
N7980_17025	COG0488	(ABC) transporter
N7980_17040	COG1404	Belongs to the peptidase S8 family
N7980_17045	COG2814	Major facilitator Superfamily
N7980_17050	COG0789	Transcriptional regulator
N7980_17060	COG0488	(ABC) transporter
N7980_17065	COG0840	transmembrane signaling receptor activity
N7980_17070	COG1012	belongs to the aldehyde dehydrogenase family
N7980_17075	COG0531	amino acid
N7980_17080	COG1011	Hydrolase
N7980_17085	COG2223	nitrite transmembrane transporter activity
N7980_17090	COG1442	glycosyl transferase family 8
N7980_17095	COG1216	Glycosyl transferase, family 2
N7980_17100	COG1442	glycosyl transferase family 8
N7980_17105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7980_17110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N7980_17115	COG1368	sulfuric ester hydrolase activity
N7980_17135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7980_17140	COG1846	Transcriptional regulator
N7980_17145	COG0697	spore germination
N7980_17150	COG0670	Belongs to the BI1 family
N7980_17155	COG5583	Uncharacterized small protein (DUF2292)
N7980_17170	COG0346	lactoylglutathione lyase activity
N7980_17175	COG2329	Antibiotic biosynthesis monooxygenase
N7980_17180	COG2323	membrane
N7980_17185	COG1486	melibiose metabolic process
N7980_17190	COG0395	ABC-type sugar transport system, permease component
N7980_17195	COG4209	transmembrane transport
N7980_17200	COG1653	transport
N7980_17210	COG1874	Beta-galactosidase
N7980_17215	COG2755	lipolytic protein G-D-S-L family
N7980_17220	COG3401	FG-GAP repeat protein
N7980_17225	COG3401	FG-GAP repeat protein
N7980_17230	COG5578	integral membrane protein
N7980_17240	COG2755	lipolytic protein G-D-S-L family
N7980_17245	COG2207	Transcriptional regulator
N7980_17250	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N7980_17255	COG0395	ABC-type sugar transport system, permease component
N7980_17260	COG1175	transmembrane transport
N7980_17265	COG1653	transport
N7980_17270	COG4753	response regulator
N7980_17270	COG2207	Transcriptional regulator
N7980_17275	COG2972	Histidine kinase
N7980_17280	COG5578	integral membrane protein
N7980_17290	COG0454	-acetyltransferase
N7980_17295	COG3546	catalase activity
N7980_17315	COG3631	Ketosteroid isomerase-related protein
N7980_17320	COG1309	transcriptional regulator
N7980_17330	COG0217	transcriptional regulatory protein
N7980_17340	COG0457	Tetratricopeptide repeat
N7980_17345	COG3391	amine dehydrogenase activity
N7980_17350	COG5444	nuclease activity
N7980_17365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N7980_17370	COG1597	lipid kinase activity
N7980_17375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7980_17385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7980_17390	COG0154	amidase activity
N7980_17395	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7980_17400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7980_17405	COG1285	pathogenesis
N7980_17410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7980_17415	COG4851	CamS sex pheromone cAM373 precursor
N7980_17420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N7980_17425	COG0210	DNA helicase
N7980_17430	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
N7980_17435	COG0069	glutamate synthase activity
N7980_17440	COG4496	protein, YerC YecD
N7980_17445	COG1470	cell adhesion involved in biofilm formation
N7980_17450	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7980_17460	COG0531	amino acid
N7980_17465	COG1522	sequence-specific DNA binding
N7980_17470	COG0151	Belongs to the GarS family
N7980_17475	COG0138	bifunctional purine biosynthesis protein purh
N7980_17480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N7980_17485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N7980_17490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N7980_17495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7980_17500	COG0047	phosphoribosylformylglycinamidine synthase activity
N7980_17505	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7980_17510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N7980_17515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N7980_17520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N7980_17525	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N7980_17535	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
N7980_17545	COG3064	Membrane
N7980_17550	COG2252	PERMEase
N7980_17565	COG0519	Catalyzes the synthesis of GMP from XMP
N7980_17565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N7980_17570	COG1305	Transglutaminase-like
N7980_17575	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
N7980_17580	COG0714	Associated with various cellular activities
N7980_17585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N7980_17595	COG1113	amino acid transport
N7980_17600	COG2132	Multicopper oxidase
N7980_17610	COG2267	carboxylic ester hydrolase activity
N7980_17625	COG0823	Involved in the tonB-independent uptake of proteins
N7980_17630	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N7980_17635	COG1063	alcohol dehydrogenase
N7980_17640	COG2814	Major facilitator Superfamily
N7980_17650	COG4260	virion core protein, lumpy skin disease virus
N7980_17655	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
N7980_17660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N7980_17665	COG1842	Phage shock protein A
N7980_17670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7980_17675	COG2211	Major facilitator Superfamily
N7980_17680	COG1063	alcohol dehydrogenase
N7980_17685	COG0457	Tetratricopeptide repeat
N7980_17690	COG1073	alpha beta
N7980_17695	COG0459	protein refolding
N7980_17705	COG1266	CAAX protease self-immunity
N7980_17715	COG0805	protein transport
N7980_17720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7980_17725	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
N7980_17730	COG0315	cyclic pyranopterin monophosphate synthase activity
N7980_17740	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N7980_17745	COG0456	acetyltransferase
N7980_17750	COG1214	PFAM Peptidase M22, glycoprotease
N7980_17755	COG0802	atpase or kinase
N7980_17760	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N7980_17805	COG4124	Belongs to the glycosyl hydrolase 26 family
N7980_17810	COG1482	cell wall glycoprotein biosynthetic process
N7980_17815	COG1940	carbohydrate kinase activity
N7980_17820	COG2188	Transcriptional regulator
N7980_17825	COG2723	6-phospho-beta-galactosidase activity
N7980_17830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7980_17835	COG1447	Phosphotransferase system cellobiose-specific component IIA
N7980_17840	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7980_17845	COG2814	Major facilitator Superfamily
N7980_17850	COG1388	LysM domain
N7980_17855	COG1078	dGTPase activity
N7980_17860	COG0454	-acetyltransferase
N7980_17870	COG5646	InterPro IPR014922
N7980_17875	COG1785	Belongs to the alkaline phosphatase family
N7980_17885	COG1819	glycosyl
N7980_17890	COG3858	chitin binding
N7980_17890	COG1388	LysM domain
N7980_17895	COG1802	Transcriptional regulator
N7980_17900	COG0730	response to heat
N7980_17905	COG2814	Major facilitator Superfamily
N7980_17910	COG1846	Transcriptional regulator
N7980_17915	COG0778	Nitroreductase
N7980_17920	COG2409	Drug exporters of the RND superfamily
N7980_17920	COG1033	growth of symbiont in host cell
N7980_17925	COG1846	Transcriptional regulator
N7980_17930	COG2318	DinB family
N7980_17935	COG1113	amino acid transport
N7980_17940	COG0488	(ABC) transporter
N7980_17945	COG0456	acetyltransferase
N7980_17955	COG1309	transcriptional regulator
N7980_17970	COG0071	Belongs to the small heat shock protein (HSP20) family
N7980_17975	COG2323	membrane
N7980_17980	COG2323	membrane
N7980_18000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7980_18005	COG2259	Doxx family
N7980_18010	COG0346	lactoylglutathione lyase activity
N7980_18015	COG0778	Nitroreductase
N7980_18020	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N7980_18025	COG4978	Transcriptional regulator
N7980_18025	COG0789	Transcriptional regulator
N7980_18030	COG1811	Na channel or pump
N7980_18035	COG0596	Alpha beta hydrolase
N7980_18040	COG2409	Drug exporters of the RND superfamily
N7980_18045	COG2197	response regulator
N7980_18050	COG4585	Histidine kinase
N7980_18065	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7980_18070	COG0640	Transcriptional regulator
N7980_18075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7980_18080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7980_18085	COG0697	spore germination
N7980_18090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7980_18100	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N7980_18105	COG0640	Transcriptional regulator
N7980_18110	COG1309	transcriptional regulator
N7980_18115	COG2814	Major facilitator Superfamily
N7980_18120	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7980_18125	COG1733	regulation of RNA biosynthetic process
N7980_18130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7980_18135	COG1733	regulation of RNA biosynthetic process
N7980_18140	COG3545	Serine hydrolase
N7980_18145	COG2030	dehydratase
N7980_18150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7980_18155	COG0697	spore germination
N7980_18160	COG1309	transcriptional regulator
N7980_18175	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
N7980_18185	COG0477	Major facilitator Superfamily
N7980_18190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7980_18195	COG3708	Transcriptional regulator
N7980_18195	COG2207	Transcriptional regulator
N7980_18200	COG0697	spore germination
N7980_18205	COG2207	Transcriptional regulator
N7980_18205	COG1917	Cupin 2, conserved barrel domain protein
N7980_18210	COG0697	spore germination
N7980_18215	COG1329	Transcriptional regulator
N7980_18220	COG1278	Cold shock
N7980_18225	COG3239	Fatty acid desaturase
N7980_18235	COG1476	TRANSCRIPTIONal
N7980_18245	COG5444	nuclease activity
N7980_18275	COG0457	Tetratricopeptide repeat
N7980_18290	COG0582	viral genome integration into host DNA
N7980_18305	COG0457	Tetratricopeptide repeat
N7980_18325	COG0741	lytic transglycosylase activity
N7980_18325	COG0791	NLP P60 protein
N7980_18330	COG5644	endopeptidase inhibitor activity
N7980_18340	COG0433	COG0433 Predicted ATPase
N7980_18375	COG2946	Replication initiation factor
N7980_18380	COG1674	ftsk spoiiie
N7980_18410	COG1396	sequence-specific DNA binding
N7980_18415	COG2856	Zn peptidase
N7980_18420	COG0582	viral genome integration into host DNA
N7980_18460	COG3091	SprT-like family
N7980_18470	COG2183	response to ionizing radiation
N7980_18475	COG2208	phosphoserine phosphatase activity
N7980_18480	COG1191	sigma factor activity
N7980_18485	COG2172	sigma factor antagonist activity
N7980_18490	COG1366	Belongs to the anti-sigma-factor antagonist family
N7980_18495	COG2208	phosphoserine phosphatase activity
N7980_18500	COG2172	sigma factor antagonist activity
N7980_18505	COG1366	Belongs to the anti-sigma-factor antagonist family
N7980_18510	COG1366	Belongs to the anti-sigma-factor antagonist family
N7980_18515	COG2337	Toxic component of a toxin-antitoxin (TA) module
N7980_18520	COG0864	Transcriptional regulator
N7980_18525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N7980_18530	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N7980_18535	COG0736	holo-[acyl-carrier-protein] synthase activity
N7980_18540	COG0705	Rhomboid family
N7980_18545	COG3428	Bacterial PH domain
N7980_18550	COG3402	PFAM membrane-flanked domain
N7980_18555	COG0513	Belongs to the DEAD box helicase family
N7980_18560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N7980_18565	COG1181	Belongs to the D-alanine--D-alanine ligase family
N7980_18570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7980_18575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N7980_18590	COG1960	acyl-CoA dehydrogenase activity
N7980_18600	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N7980_18605	COG1131	(ABC) transporter
N7980_18610	COG0628	permease
N7980_18615	COG1301	dicarboxylic acid transport
N7980_18620	COG4565	transcriptional regulatory protein
N7980_18625	COG3290	protein histidine kinase activity
N7980_18630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N7980_18635	COG3546	catalase activity
N7980_18640	COG2329	Antibiotic biosynthesis monooxygenase
N7980_18645	COG0662	Cupin 2, conserved barrel domain protein
N7980_18650	COG3729	General stress protein
N7980_18655	COG2217	Heavy metal translocating P-type atpase
N7980_18660	COG4876	unkown
N7980_18665	COG2261	transglycosylase associated protein
N7980_18670	COG1914	H( )-stimulated, divalent metal cation uptake system
N7980_18685	COG0028	Belongs to the TPP enzyme family
N7980_18690	COG0494	nUDIX hydrolase
N7980_18695	COG0531	amino acid
N7980_18705	COG1215	transferase activity, transferring glycosyl groups
N7980_18710	COG5298	Protein conserved in bacteria
N7980_18715	COG3706	GGDEF domain
N7980_18720	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
N7980_18725	COG0551	DNA topoisomerase type I activity
N7980_18725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N7980_18730	COG1522	sequence-specific DNA binding
N7980_18735	COG2814	Major facilitator Superfamily
N7980_18745	COG3871	stress protein (general stress protein 26)
N7980_18750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7980_18755	COG1917	Cupin 2, conserved barrel domain protein
N7980_18760	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_18765	COG2226	methyltransferase
N7980_18770	COG0318	PFAM AMP-dependent synthetase and ligase
N7980_18775	COG3711	transcriptional antiterminator
N7980_18780	COG4989	oxidoreductase activity
N7980_18785	COG0768	penicillin binding
N7980_18790	COG2329	Antibiotic biosynthesis monooxygenase
N7980_18800	COG2755	lipolytic protein G-D-S-L family
N7980_18805	COG1414	Transcriptional regulator
N7980_18810	COG1984	allophanate hydrolase subunit 2
N7980_18815	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
N7980_18820	COG4336	lyase activity
N7980_18825	COG1914	H( )-stimulated, divalent metal cation uptake system
N7980_18830	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
N7980_18835	COG0561	phosphatase activity
N7980_18845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N7980_18850	COG0412	Dienelactone hydrolase
N7980_18855	COG0681	Belongs to the peptidase S26 family
N7980_18860	COG0473	3-isopropylmalate dehydrogenase activity
N7980_18865	COG0246	Mannitol dehydrogenase
N7980_18870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7980_18875	COG2213	PTS system mannitol-specific
N7980_18885	COG1349	DNA-binding transcription factor activity
N7980_18890	COG2372	response to copper ion
N7980_18890	COG1276	copper resistance
N7980_18895	COG4549	nuclear export factor GLE1
N7980_18900	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_18905	COG4975	Glucose uptake
N7980_18910	COG1012	belongs to the aldehyde dehydrogenase family
N7980_18915	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7980_18920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7980_18925	COG0640	Transcriptional regulator
N7980_18930	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N7980_18935	COG0778	Nitroreductase
N7980_18940	COG1309	transcriptional regulator
N7980_18945	COG2814	Major facilitator Superfamily
N7980_18950	COG4607	ABC-type enterochelin transport system periplasmic component
N7980_18955	COG4604	ABC transporter, ATP-binding protein
N7980_18960	COG4605	iron ion homeostasis
N7980_18965	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7980_18970	COG0527	aspartate kinase activity
N7980_18990	COG0457	Tetratricopeptide repeat
N7980_18995	COG3850	Histidine kinase
N7980_18995	COG5002	protein histidine kinase activity
N7980_19000	COG0745	RESPONSE REGULATOR receiver
N7980_19005	COG0577	efflux transmembrane transporter activity
N7980_19010	COG1136	(ABC) transporter
N7980_19015	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N7980_19025	COG0697	spore germination
N7980_19035	COG5434	Belongs to the glycosyl hydrolase 28 family
N7980_19040	COG3104	oligopeptide transport
N7980_19045	COG0596	Alpha beta hydrolase
N7980_19060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N7980_19065	COG0163	prenyltransferase activity
N7980_19070	COG0583	DNA-binding transcription factor activity
N7980_19075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7980_19080	COG0765	amino acid transport
N7980_19085	COG1126	abc transporter atp-binding protein
N7980_19090	COG2364	Membrane
N7980_19100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7980_19105	COG0697	spore germination
N7980_19115	COG2814	Major facilitator Superfamily
N7980_19120	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N7980_19125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_19130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_19150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7980_19155	COG1733	regulation of RNA biosynthetic process
N7980_19160	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
N7980_19165	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N7980_19170	COG3290	protein histidine kinase activity
N7980_19170	COG0840	transmembrane signaling receptor activity
N7980_19175	COG3209	COG3209 Rhs family protein
N7980_19185	COG2723	6-phospho-beta-galactosidase activity
N7980_19195	COG1714	RDD family
N7980_19205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7980_19210	COG0765	amino acid transport
N7980_19215	COG0523	cobalamin synthesis protein
N7980_19225	COG1376	ErfK ybiS ycfS ynhG family protein
N7980_19230	COG1469	GTP cyclohydrolase I activity
N7980_19235	COG2223	nitrite transmembrane transporter activity
N7980_19240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7980_19245	COG0243	molybdopterin cofactor binding
N7980_19250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7980_19255	COG2146	nitrite reductase [NAD(P)H] activity
N7980_19260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N7980_19260	COG1587	Uroporphyrinogen-III synthase
N7980_19265	COG0492	ferredoxin-NADP+ reductase activity
N7980_19270	COG2267	carboxylic ester hydrolase activity
N7980_19275	COG0701	Predicted permease
N7980_19280	COG3689	TIGRFAM TIGR03943 family protein
N7980_19285	COG2508	Transcriptional regulator
N7980_19290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7980_19295	COG1012	belongs to the aldehyde dehydrogenase family
N7980_19300	COG0506	proline dehydrogenase activity
N7980_19305	COG3541	Predicted nucleotidyltransferase
N7980_19310	COG3458	cephalosporin-C deacetylase activity
N7980_19315	COG0583	DNA-binding transcription factor activity
N7980_19320	COG2226	methyltransferase
N7980_19325	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N7980_19330	COG1660	Displays ATPase and GTPase activities
N7980_19335	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N7980_19340	COG3665	Urea carboxylase-associated protein
N7980_19345	COG1113	amino acid transport
N7980_19350	COG3403	YqcI/YcgG family
N7980_19355	COG1280	lysine exporter protein (LysE YggA)
N7980_19360	COG1846	Transcriptional regulator
N7980_19365	COG2814	Major facilitator Superfamily
N7980_19370	COG1620	l-lactate permease
N7980_19375	COG0039	L-malate dehydrogenase activity
N7980_19380	COG0366	Alpha amylase catalytic
N7980_19390	COG1288	antiporter activity
N7980_19395	COG1473	amidohydrolase
N7980_19400	COG2113	Glycine betaine
N7980_19405	COG4176	ABC-type proline glycine betaine transport system permease component
N7980_19410	COG4175	Glycine betaine
N7980_19410	COG0517	IMP dehydrogenase activity
N7980_19415	COG0640	Transcriptional regulator
N7980_19420	COG2814	Major facilitator Superfamily
N7980_19425	COG0477	Major facilitator Superfamily
N7980_19430	COG3853	Toxic anion resistance protein (TelA)
N7980_19440	COG0861	Integral membrane protein TerC family
N7980_19445	COG2310	stress, protein
N7980_19450	COG2310	stress, protein
N7980_19455	COG2310	stress, protein
N7980_19460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7980_19465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7980_19470	COG1121	(ABC) transporter
N7980_19475	COG0803	Belongs to the bacterial solute-binding protein 9 family
N7980_19480	COG0366	Alpha amylase catalytic
N7980_19485	COG1028	Short-chain dehydrogenase reductase Sdr
N7980_19490	COG0457	Tetratricopeptide repeat
N7980_19495	COG1876	peptidase activity
N7980_19500	COG1595	DNA-templated transcription, initiation
N7980_19505	COG1595	DNA-templated transcription, initiation
N7980_19520	COG0667	Aldo Keto reductase
N7980_19525	COG1668	transmembrane transport
N7980_19530	COG4555	ABC transporter
N7980_19535	COG3279	Response regulator of the LytR AlgR family
N7980_19540	COG3290	protein histidine kinase activity
N7980_19545	COG3012	SEC-C Motif Domain Protein
N7980_19545	COG1405	negative regulation of cell septum assembly
N7980_19550	COG1714	RDD family
N7980_19555	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N7980_19560	COG0252	asparaginase activity
N7980_19565	COG1309	transcriptional regulator
N7980_19570	COG0477	Major facilitator Superfamily
N7980_19575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N7980_19580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
N7980_19585	COG0805	protein transport
N7980_19590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7980_19595	COG3540	Alkaline phosphatase
N7980_19605	COG2304	oxidoreductase activity
N7980_19610	COG3773	Cell wall hydrolase
N7980_19630	COG1131	(ABC) transporter
N7980_19635	COG2205	protein histidine kinase activity
N7980_19640	COG0745	RESPONSE REGULATOR receiver
N7980_19645	COG0697	spore germination
N7980_19655	COG3173	Aminoglycoside phosphotransferase
N7980_19660	COG2721	sulfolactate sulfo-lyase activity
N7980_19665	COG2186	Transcriptional regulator
N7980_19670	COG4948	Mandelate Racemase Muconate Lactonizing
N7980_19675	COG2271	Major facilitator Superfamily
N7980_19680	COG1012	belongs to the aldehyde dehydrogenase family
N7980_19685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7980_19690	COG0784	Response regulator, receiver
N7980_19695	COG4191	Histidine kinase
N7980_19700	COG2066	Belongs to the glutaminase family
N7980_19705	COG1115	amino acid carrier protein
N7980_19710	COG2040	homocysteine
N7980_19715	COG0833	amino acid
N7980_19720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7980_19730	COG2188	Transcriptional regulator
N7980_19735	COG0363	glucosamine-6-phosphate deaminase activity
N7980_19740	COG2190	(PTS) system
N7980_19740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_19740	COG1263	PTS System
N7980_19745	COG1301	dicarboxylic acid transport
N7980_19750	COG1054	Belongs to the UPF0176 family
N7980_19755	COG2312	Erythromycin esterase
N7980_19765	COG0688	phosphatidylethanolamine metabolic process
N7980_19770	COG0586	Pfam SNARE associated Golgi protein
N7980_19775	COG1183	phosphatidylcholine synthase activity
N7980_19780	COG0596	Alpha beta hydrolase
N7980_19790	COG3591	Belongs to the peptidase S1B family
N7980_19795	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
N7980_19800	COG5444	nuclease activity
N7980_19805	COG1397	ADP-ribosylglycohydrolase
N7980_19810	COG1917	Cupin 2, conserved barrel domain protein
N7980_19810	COG2207	Transcriptional regulator
N7980_19815	COG0697	spore germination
N7980_19820	COG3409	Peptidoglycan-binding domain 1 protein
N7980_19830	COG2271	Major facilitator Superfamily
N7980_19835	COG0456	acetyltransferase
N7980_19835	COG1846	Transcriptional regulator
N7980_19845	COG2271	Major facilitator Superfamily
N7980_19850	COG0584	glycerophosphoryl diester phosphodiesterase
N7980_19855	COG0531	amino acid
N7980_19865	COG2124	cytochrome p450
N7980_19870	COG2602	Beta-lactamase
N7980_19885	COG1113	amino acid transport
N7980_19900	COG0515	serine threonine protein kinase
N7980_19915	COG2814	Major facilitator Superfamily
N7980_19920	COG0640	Transcriptional regulator
N7980_19925	COG5609	conserved protein (DUF2294)
N7980_19935	COG0288	reversible hydration of carbon dioxide
N7980_19940	COG3002	Belongs to the UPF0753 family
N7980_19945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N7980_19950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7980_19955	COG2169	Transcriptional regulator
N7980_19960	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N7980_19970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N7980_19975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7980_19980	COG4856	YbbR-like protein
N7980_19985	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N7980_19990	COG5662	AntiSigma factor
N7980_19995	COG1595	DNA-templated transcription, initiation
N7980_20025	COG1683	Conserved Protein
N7980_20030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7980_20035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N7980_20040	COG1737	Transcriptional regulator
N7980_20045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7980_20045	COG1263	PTS System
N7980_20050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7980_20055	COG1472	Belongs to the glycosyl hydrolase 3 family
N7980_20060	COG3876	Protein conserved in bacteria
N7980_20065	COG2207	Transcriptional regulator
N7980_20065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7980_20070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7980_20075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7980_20080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7980_20085	COG2819	hydrolase of the alpha beta superfamily
N7980_20090	COG0385	Bile acid
N7980_20095	COG0659	secondary active sulfate transmembrane transporter activity
N7980_20180	COG0726	polysaccharide deacetylase
N7980_20185	COG2194	sulfuric ester hydrolase activity
N7980_20195	COG0489	protein tyrosine kinase activity
N7980_20200	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7980_20210	COG2226	methyltransferase
N7980_20215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N7980_20220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N7980_20225	COG0101	tRNA pseudouridine synthase activity
N7980_20230	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N7980_20235	COG1122	ATPase activity
N7980_20240	COG1122	ATPase activity
N7980_20245	COG0203	ribosomal protein L17
N7980_20250	COG0202	RNA polymerase activity
N7980_20255	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N7980_20260	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N7980_20265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N7980_20275	COG2163	COG2163 Ribosomal protein L14E L6E L27E
N7980_20280	COG0024	Methionine aminopeptidase
N7980_20285	COG0563	adenylate kinase activity
N7980_20290	COG0201	protein transport
N7980_20295	COG0200	Binds to the 23S rRNA
N7980_20305	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N7980_20310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N7980_20315	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N7980_20320	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N7980_20330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N7980_20340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N7980_20345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N7980_20355	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N7980_20360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N7980_20375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N7980_20385	COG0088	Forms part of the polypeptide exit tunnel
N7980_20390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N7980_20400	COG0596	Alpha beta hydrolase
N7980_20405	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N7980_20410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N7980_20415	COG0049	tRNA binding
N7980_20420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N7980_20425	COG1358	cellular component organization or biogenesis
N7980_20430	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N7980_20435	COG0085	RNA polymerase activity
N7980_20440	COG2813	Specifically methylates the guanine in position
N7980_20450	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N7980_20455	COG0081	regulation of translation
N7980_20465	COG0250	Participates in transcription elongation, termination and antitermination
N7980_20470	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N7980_20480	COG1595	DNA-templated transcription, initiation
N7980_20485	COG3688	RNA-binding protein containing a PIN domain
N7980_20490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7980_20495	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
N7980_20500	COG0215	cysteine-tRNA ligase activity
N7980_20505	COG1045	serine acetyltransferase
N7980_20510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7980_20515	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N7980_20520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N7980_20525	COG4956	integral membrane protein (PIN domain superfamily)
N7980_20530	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
N7980_20535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N7980_20540	COG0542	response to heat
N7980_20545	COG3869	Catalyzes the specific phosphorylation of arginine residues in
N7980_20550	COG3880	PFAM UvrB UvrC protein
N7980_20555	COG4463	regulation of RNA biosynthetic process
N7980_20635	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N7980_20640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N7980_20645	COG1396	sequence-specific DNA binding
N7980_20650	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N7980_20655	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N7980_20660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N7980_20665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7980_20670	COG0512	Glutamine amidotransferase of anthranilate synthase
N7980_20675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N7980_20680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7980_20685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N7980_20690	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N7980_20695	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
N7980_20700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N7980_20705	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
N7980_20710	COG0037	tRNA processing
N7980_20715	COG0515	serine threonine protein kinase
N7980_20720	COG2304	oxidoreductase activity
N7980_20725	COG2208	phosphoserine phosphatase activity
N7980_20740	COG1098	S1 RNA binding domain
N7980_20745	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N7980_20760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N7980_20765	COG3956	TIGRFAM MazG family protein
N7980_20770	COG2244	polysaccharide biosynthetic process
N7980_20775	COG2002	toxin-antitoxin pair type II binding
N7980_20780	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N7980_20790	COG0193	aminoacyl-tRNA hydrolase activity
N7980_20795	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N7980_20800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N7980_20805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N7980_20810	COG2088	sporulation resulting in formation of a cellular spore
N7980_20815	COG0251	oxidation-reduction process
N7980_20820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7980_20825	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N7980_20835	COG4466	Protein conserved in bacteria
N7980_20845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N7980_20850	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N7980_20855	COG3583	domain protein
N7980_20855	COG3584	3D domain protein
N7980_20860	COG0084	hydrolase, TatD family'
N7980_20865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7980_20865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7980_20870	COG2002	toxin-antitoxin pair type II binding
N7980_20875	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N7980_20880	COG2827	Endonuclease containing a URI domain
N7980_20885	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N7980_20890	COG4467	Involved in initiation control of chromosome replication
N7980_20895	COG1774	PSP1 C-terminal conserved region
N7980_20900	COG0470	DNA polymerase III
N7980_20905	COG1728	Protein conserved in bacteria
N7980_20910	COG3870	Protein conserved in bacteria
N7980_20915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N7980_20920	COG1982	Orn Lys Arg decarboxylase major
N7980_20925	COG3853	Toxic anion resistance protein (TelA)
N7980_20930	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
N7980_20975	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N7980_20980	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N7980_20985	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N7980_20995	COG0590	tRNA wobble adenosine to inosine editing
N7980_21000	COG1335	isochorismatase
N7980_21005	COG3858	chitin binding
N7980_21005	COG1388	LysM domain
N7980_21010	COG1428	Deoxynucleoside kinase
N7980_21015	COG1428	Deoxynucleoside kinase
N7980_21025	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N7980_21030	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
N7980_21035	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
N7980_21040	COG1686	Belongs to the peptidase S11 family
N7980_21045	COG0517	IMP dehydrogenase activity
N7980_21045	COG0516	GMP reductase activity
N7980_21080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7980_21085	COG0187	DNA topoisomerase II activity
N7980_21095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N7980_21100	COG2501	S4 domain
N7980_21105	COG0592	DNA-directed DNA polymerase activity
N7980_21135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N7980_21175	COG0328	RNA-DNA hybrid ribonuclease activity
N7980_21195	COG0587	DNA-directed DNA polymerase activity
N7980_21220	COG0194	GDP metabolic process
N7980_21270	COG0187	DNA topoisomerase II activity
N7980_21275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7980_21325	COG5444	nuclease activity
N7980_21380	COG5280	Phage tail tape measure protein TP901
N7980_21380	COG3953	SLT domain
N7980_21470	COG0457	Tetratricopeptide repeat
N7980_21490	COG3584	3D domain protein
N7980_21490	COG1388	LysM domain
N7980_21500	COG0582	viral genome integration into host DNA
N7980_21570	COG2887	Belongs to the helicase family. UvrD subfamily
N7980_21575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7980_21580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7980_21585	COG0716	FMN binding