locus-tag	class	description
NX823_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NX823_00010	COG0592	DNA-directed DNA polymerase activity
NX823_00015	COG2501	S4 domain
NX823_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NX823_00030	COG0187	DNA topoisomerase II activity
NX823_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NX823_00075	COG0516	GMP reductase activity
NX823_00075	COG0517	IMP dehydrogenase activity
NX823_00080	COG1686	Belongs to the peptidase S11 family
NX823_00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NX823_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NX823_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NX823_00105	COG1428	Deoxynucleoside kinase
NX823_00110	COG1428	Deoxynucleoside kinase
NX823_00115	COG1388	LysM domain
NX823_00115	COG3858	chitin binding
NX823_00120	COG1335	isochorismatase
NX823_00125	COG0590	tRNA wobble adenosine to inosine editing
NX823_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NX823_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NX823_00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NX823_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NX823_00195	COG3853	Toxic anion resistance protein (TelA)
NX823_00200	COG1982	Orn Lys Arg decarboxylase major
NX823_00205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NX823_00210	COG3870	Protein conserved in bacteria
NX823_00215	COG1728	Protein conserved in bacteria
NX823_00220	COG0470	DNA polymerase III
NX823_00225	COG1774	PSP1 C-terminal conserved region
NX823_00230	COG4467	Involved in initiation control of chromosome replication
NX823_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NX823_00240	COG2827	Endonuclease containing a URI domain
NX823_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NX823_00250	COG2002	toxin-antitoxin pair type II binding
NX823_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX823_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX823_00260	COG0084	hydrolase, TatD family'
NX823_00265	COG3583	domain protein
NX823_00265	COG3584	3D domain protein
NX823_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NX823_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NX823_00285	COG4466	Protein conserved in bacteria
NX823_00295	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NX823_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NX823_00305	COG0251	oxidation-reduction process
NX823_00310	COG2088	sporulation resulting in formation of a cellular spore
NX823_00315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NX823_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NX823_00325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NX823_00330	COG0193	aminoacyl-tRNA hydrolase activity
NX823_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NX823_00345	COG2002	toxin-antitoxin pair type II binding
NX823_00350	COG2244	polysaccharide biosynthetic process
NX823_00355	COG3956	TIGRFAM MazG family protein
NX823_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NX823_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NX823_00380	COG1098	S1 RNA binding domain
NX823_00395	COG2208	phosphoserine phosphatase activity
NX823_00400	COG2304	oxidoreductase activity
NX823_00405	COG0515	serine threonine protein kinase
NX823_00410	COG0037	tRNA processing
NX823_00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NX823_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NX823_00425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NX823_00430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NX823_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NX823_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NX823_00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NX823_00455	COG0512	Glutamine amidotransferase of anthranilate synthase
NX823_00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX823_00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NX823_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NX823_00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NX823_00480	COG1396	sequence-specific DNA binding
NX823_00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NX823_00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NX823_00570	COG4463	regulation of RNA biosynthetic process
NX823_00575	COG3880	PFAM UvrB UvrC protein
NX823_00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NX823_00585	COG0542	response to heat
NX823_00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NX823_00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NX823_00600	COG4956	integral membrane protein (PIN domain superfamily)
NX823_00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NX823_00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NX823_00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NX823_00620	COG1045	serine acetyltransferase
NX823_00625	COG0215	cysteine-tRNA ligase activity
NX823_00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NX823_00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NX823_00640	COG3688	RNA-binding protein containing a PIN domain
NX823_00645	COG1595	DNA-templated transcription, initiation
NX823_00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NX823_00660	COG0250	Participates in transcription elongation, termination and antitermination
NX823_00670	COG0081	regulation of translation
NX823_00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NX823_00685	COG2813	Specifically methylates the guanine in position
NX823_00690	COG0085	RNA polymerase activity
NX823_00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NX823_00700	COG1358	cellular component organization or biogenesis
NX823_00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NX823_00710	COG0049	tRNA binding
NX823_00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NX823_00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NX823_00725	COG0596	Alpha beta hydrolase
NX823_00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NX823_00740	COG0088	Forms part of the polypeptide exit tunnel
NX823_00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NX823_00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NX823_00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NX823_00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NX823_00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NX823_00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NX823_00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NX823_00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NX823_00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NX823_00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NX823_00830	COG0200	Binds to the 23S rRNA
NX823_00835	COG0201	protein transport
NX823_00840	COG0563	adenylate kinase activity
NX823_00845	COG0024	Methionine aminopeptidase
NX823_00850	COG2163	COG2163 Ribosomal protein L14E L6E L27E
NX823_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NX823_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NX823_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NX823_00875	COG0202	RNA polymerase activity
NX823_00880	COG0203	ribosomal protein L17
NX823_00885	COG1122	ATPase activity
NX823_00890	COG1122	ATPase activity
NX823_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NX823_00900	COG0101	tRNA pseudouridine synthase activity
NX823_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NX823_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NX823_00915	COG2226	methyltransferase
NX823_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX823_00930	COG0489	protein tyrosine kinase activity
NX823_00940	COG2194	sulfuric ester hydrolase activity
NX823_00945	COG0726	polysaccharide deacetylase
NX823_01030	COG0659	secondary active sulfate transmembrane transporter activity
NX823_01035	COG0385	Bile acid
NX823_01040	COG2819	hydrolase of the alpha beta superfamily
NX823_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX823_01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX823_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX823_01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX823_01060	COG2207	Transcriptional regulator
NX823_01065	COG3876	Protein conserved in bacteria
NX823_01070	COG1472	Belongs to the glycosyl hydrolase 3 family
NX823_01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NX823_01080	COG1263	PTS System
NX823_01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX823_01085	COG1737	Transcriptional regulator
NX823_01090	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NX823_01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX823_01100	COG1683	Conserved Protein
NX823_01130	COG1595	DNA-templated transcription, initiation
NX823_01135	COG5662	AntiSigma factor
NX823_01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NX823_01145	COG4856	YbbR-like protein
NX823_01150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NX823_01155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NX823_01200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NX823_01205	COG3002	Belongs to the UPF0753 family
NX823_01210	COG0288	reversible hydration of carbon dioxide
NX823_01220	COG5609	conserved protein (DUF2294)
NX823_01230	COG0642	Histidine kinase
NX823_01240	COG0515	serine threonine protein kinase
NX823_01255	COG1113	amino acid transport
NX823_01270	COG2602	Beta-lactamase
NX823_01275	COG2124	cytochrome p450
NX823_01285	COG0531	amino acid
NX823_01290	COG0584	glycerophosphoryl diester phosphodiesterase
NX823_01295	COG2271	Major facilitator Superfamily
NX823_01305	COG0456	acetyltransferase
NX823_01305	COG1846	Transcriptional regulator
NX823_01320	COG3409	Peptidoglycan-binding domain 1 protein
NX823_01325	COG0697	spore germination
NX823_01330	COG1917	Cupin 2, conserved barrel domain protein
NX823_01330	COG2207	Transcriptional regulator
NX823_01355	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NX823_01360	COG3591	Belongs to the peptidase S1B family
NX823_01370	COG0596	Alpha beta hydrolase
NX823_01375	COG1183	phosphatidylcholine synthase activity
NX823_01380	COG0586	Pfam SNARE associated Golgi protein
NX823_01385	COG0688	phosphatidylethanolamine metabolic process
NX823_01395	COG2312	Erythromycin esterase
NX823_01400	COG2207	Transcriptional regulator
NX823_01405	COG1054	Belongs to the UPF0176 family
NX823_01410	COG1301	dicarboxylic acid transport
NX823_01415	COG1263	PTS System
NX823_01415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX823_01415	COG2190	(PTS) system
NX823_01420	COG0363	glucosamine-6-phosphate deaminase activity
NX823_01425	COG2188	Transcriptional regulator
NX823_01435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX823_01445	COG0833	amino acid
NX823_01450	COG2040	homocysteine
NX823_01455	COG1115	amino acid carrier protein
NX823_01460	COG2066	Belongs to the glutaminase family
NX823_01465	COG4191	Histidine kinase
NX823_01470	COG0784	Response regulator, receiver
NX823_01475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NX823_01480	COG1012	belongs to the aldehyde dehydrogenase family
NX823_01485	COG2271	Major facilitator Superfamily
NX823_01490	COG4948	Mandelate Racemase Muconate Lactonizing
NX823_01495	COG2186	Transcriptional regulator
NX823_01515	COG0697	spore germination
NX823_01520	COG0745	RESPONSE REGULATOR receiver
NX823_01525	COG2205	protein histidine kinase activity
NX823_01530	COG1131	(ABC) transporter
NX823_01550	COG3773	Cell wall hydrolase
NX823_01555	COG2304	oxidoreductase activity
NX823_01565	COG3540	Alkaline phosphatase
NX823_01570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NX823_01575	COG0805	protein transport
NX823_01580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NX823_01585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NX823_01590	COG0477	Major facilitator Superfamily
NX823_01595	COG1309	transcriptional regulator
NX823_01600	COG0252	asparaginase activity
NX823_01605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NX823_01610	COG1714	RDD family
NX823_01615	COG1405	negative regulation of cell septum assembly
NX823_01615	COG3012	SEC-C Motif Domain Protein
NX823_01620	COG3290	protein histidine kinase activity
NX823_01625	COG3279	Response regulator of the LytR AlgR family
NX823_01630	COG4555	ABC transporter
NX823_01635	COG1668	transmembrane transport
NX823_01655	COG1595	DNA-templated transcription, initiation
NX823_01660	COG1595	DNA-templated transcription, initiation
NX823_01675	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_01685	COG0803	Belongs to the bacterial solute-binding protein 9 family
NX823_01690	COG1121	(ABC) transporter
NX823_01695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NX823_01700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX823_01705	COG2310	stress, protein
NX823_01710	COG2310	stress, protein
NX823_01715	COG2310	stress, protein
NX823_01720	COG0861	Integral membrane protein TerC family
NX823_01730	COG3853	Toxic anion resistance protein (TelA)
NX823_01740	COG0477	Major facilitator Superfamily
NX823_01745	COG2814	Major facilitator Superfamily
NX823_01750	COG0640	Transcriptional regulator
NX823_01755	COG0517	IMP dehydrogenase activity
NX823_01755	COG4175	Glycine betaine
NX823_01760	COG4176	ABC-type proline glycine betaine transport system permease component
NX823_01765	COG2113	Glycine betaine
NX823_01770	COG1473	amidohydrolase
NX823_01775	COG1288	antiporter activity
NX823_01790	COG0039	L-malate dehydrogenase activity
NX823_01805	COG3403	YqcI/YcgG family
NX823_01815	COG3665	Urea carboxylase-associated protein
NX823_01820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NX823_01825	COG1660	Displays ATPase and GTPase activities
NX823_01830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NX823_01835	COG2226	methyltransferase
NX823_01840	COG0583	DNA-binding transcription factor activity
NX823_01845	COG3458	cephalosporin-C deacetylase activity
NX823_01850	COG3541	Predicted nucleotidyltransferase
NX823_01855	COG0506	proline dehydrogenase activity
NX823_01860	COG1012	belongs to the aldehyde dehydrogenase family
NX823_01865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX823_01870	COG2508	Transcriptional regulator
NX823_01875	COG3689	TIGRFAM TIGR03943 family protein
NX823_01880	COG0701	Predicted permease
NX823_01885	COG2267	carboxylic ester hydrolase activity
NX823_01890	COG0492	ferredoxin-NADP+ reductase activity
NX823_01895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NX823_01895	COG1587	Uroporphyrinogen-III synthase
NX823_01900	COG2146	nitrite reductase [NAD(P)H] activity
NX823_01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NX823_01910	COG0243	molybdopterin cofactor binding
NX823_01915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NX823_01920	COG2223	nitrite transmembrane transporter activity
NX823_01930	COG1376	ErfK ybiS ycfS ynhG family protein
NX823_01945	COG0765	amino acid transport
NX823_01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX823_01960	COG1714	RDD family
NX823_01970	COG1846	Transcriptional regulator
NX823_01985	COG2723	6-phospho-beta-galactosidase activity
NX823_01995	COG3209	COG3209 Rhs family protein
NX823_02005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NX823_02010	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NX823_02015	COG1733	regulation of RNA biosynthetic process
NX823_02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX823_02040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX823_02045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX823_02050	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NX823_02055	COG2814	Major facilitator Superfamily
NX823_02065	COG0697	spore germination
NX823_02070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX823_02080	COG2364	Membrane
NX823_02085	COG1126	abc transporter atp-binding protein
NX823_02090	COG0765	amino acid transport
NX823_02095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX823_02100	COG0583	DNA-binding transcription factor activity
NX823_02110	COG0596	Alpha beta hydrolase
NX823_02115	COG3104	oligopeptide transport
NX823_02120	COG5434	Belongs to the glycosyl hydrolase 28 family
NX823_02130	COG0697	spore germination
NX823_02140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NX823_02145	COG1136	(ABC) transporter
NX823_02150	COG0577	efflux transmembrane transporter activity
NX823_02155	COG0745	RESPONSE REGULATOR receiver
NX823_02160	COG3850	Histidine kinase
NX823_02160	COG5002	protein histidine kinase activity
NX823_02165	COG0457	Tetratricopeptide repeat
NX823_02185	COG0527	aspartate kinase activity
NX823_02190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX823_02195	COG4605	iron ion homeostasis
NX823_02200	COG4604	ABC transporter, ATP-binding protein
NX823_02205	COG4607	ABC-type enterochelin transport system periplasmic component
NX823_02220	COG2814	Major facilitator Superfamily
NX823_02225	COG1309	transcriptional regulator
NX823_02230	COG0778	Nitroreductase
NX823_02235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NX823_02240	COG0640	Transcriptional regulator
NX823_02245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX823_02250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NX823_02255	COG1012	belongs to the aldehyde dehydrogenase family
NX823_02260	COG4975	Glucose uptake
NX823_02265	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_02270	COG4549	nuclear export factor GLE1
NX823_02275	COG1276	copper resistance
NX823_02275	COG2372	response to copper ion
NX823_02280	COG1349	DNA-binding transcription factor activity
NX823_02290	COG2213	PTS system mannitol-specific
NX823_02295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX823_02300	COG0246	Mannitol dehydrogenase
NX823_02305	COG0473	3-isopropylmalate dehydrogenase activity
NX823_02310	COG0681	Belongs to the peptidase S26 family
NX823_02320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NX823_02330	COG0561	phosphatase activity
NX823_02335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NX823_02340	COG1914	H( )-stimulated, divalent metal cation uptake system
NX823_02345	COG4336	lyase activity
NX823_02350	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NX823_02355	COG1984	allophanate hydrolase subunit 2
NX823_02360	COG1414	Transcriptional regulator
NX823_02365	COG2755	lipolytic protein G-D-S-L family
NX823_02375	COG2329	Antibiotic biosynthesis monooxygenase
NX823_02380	COG0768	penicillin binding
NX823_02385	COG4989	oxidoreductase activity
NX823_02395	COG3711	transcriptional antiterminator
NX823_02400	COG0318	PFAM AMP-dependent synthetase and ligase
NX823_02405	COG2226	methyltransferase
NX823_02410	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_02415	COG1917	Cupin 2, conserved barrel domain protein
NX823_02420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX823_02425	COG3871	stress protein (general stress protein 26)
NX823_02435	COG2814	Major facilitator Superfamily
NX823_02440	COG1522	sequence-specific DNA binding
NX823_02445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NX823_02445	COG0551	DNA topoisomerase type I activity
NX823_02450	COG0494	nUDIX hydrolase
NX823_02455	COG0028	Belongs to the TPP enzyme family
NX823_02480	COG1914	H( )-stimulated, divalent metal cation uptake system
NX823_02485	COG2261	transglycosylase associated protein
NX823_02490	COG4876	unkown
NX823_02495	COG2217	Heavy metal translocating P-type atpase
NX823_02505	COG0662	Cupin 2, conserved barrel domain protein
NX823_02510	COG2329	Antibiotic biosynthesis monooxygenase
NX823_02515	COG3546	catalase activity
NX823_02520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NX823_02525	COG3290	protein histidine kinase activity
NX823_02530	COG4565	transcriptional regulatory protein
NX823_02535	COG1301	dicarboxylic acid transport
NX823_02540	COG0628	permease
NX823_02550	COG1131	(ABC) transporter
NX823_02555	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NX823_02565	COG1960	acyl-CoA dehydrogenase activity
NX823_02585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NX823_02590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX823_02595	COG1181	Belongs to the D-alanine--D-alanine ligase family
NX823_02600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NX823_02605	COG0513	Belongs to the DEAD box helicase family
NX823_02610	COG3402	PFAM membrane-flanked domain
NX823_02615	COG3428	Bacterial PH domain
NX823_02620	COG0705	Rhomboid family
NX823_02625	COG0736	holo-[acyl-carrier-protein] synthase activity
NX823_02630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NX823_02635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NX823_02640	COG0864	Transcriptional regulator
NX823_02645	COG2337	Toxic component of a toxin-antitoxin (TA) module
NX823_02650	COG1366	Belongs to the anti-sigma-factor antagonist family
NX823_02655	COG1366	Belongs to the anti-sigma-factor antagonist family
NX823_02660	COG2172	sigma factor antagonist activity
NX823_02665	COG2208	phosphoserine phosphatase activity
NX823_02670	COG1366	Belongs to the anti-sigma-factor antagonist family
NX823_02675	COG2172	sigma factor antagonist activity
NX823_02685	COG2208	phosphoserine phosphatase activity
NX823_02690	COG2183	response to ionizing radiation
NX823_02700	COG3091	SprT-like family
NX823_02745	COG0583	DNA-binding transcription factor activity
NX823_02750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX823_02760	COG5444	nuclease activity
NX823_02790	COG1476	TRANSCRIPTIONal
NX823_02800	COG3239	Fatty acid desaturase
NX823_02805	COG1278	Cold shock
NX823_02810	COG1329	Transcriptional regulator
NX823_02820	COG0697	spore germination
NX823_02825	COG2207	Transcriptional regulator
NX823_02825	COG1917	Cupin 2, conserved barrel domain protein
NX823_02830	COG0697	spore germination
NX823_02835	COG2207	Transcriptional regulator
NX823_02835	COG3708	Transcriptional regulator
NX823_02840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX823_02855	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
NX823_02865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX823_02870	COG1309	transcriptional regulator
NX823_02875	COG0697	spore germination
NX823_02885	COG2030	dehydratase
NX823_02890	COG3545	Serine hydrolase
NX823_02895	COG1733	regulation of RNA biosynthetic process
NX823_02900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX823_02905	COG0640	Transcriptional regulator
NX823_02910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NX823_02920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX823_02925	COG0697	spore germination
NX823_02930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX823_02935	COG0076	glutamate decarboxylase activity
NX823_02940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NX823_02945	COG0640	Transcriptional regulator
NX823_02950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NX823_02965	COG4585	Histidine kinase
NX823_02970	COG2197	response regulator
NX823_02975	COG2409	Drug exporters of the RND superfamily
NX823_02985	COG0596	Alpha beta hydrolase
NX823_02990	COG1811	Na channel or pump
NX823_02995	COG4978	Transcriptional regulator
NX823_02995	COG0789	Transcriptional regulator
NX823_03000	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NX823_03005	COG0778	Nitroreductase
NX823_03010	COG0346	lactoylglutathione lyase activity
NX823_03015	COG2259	Doxx family
NX823_03020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX823_03045	COG2323	membrane
NX823_03050	COG0071	Belongs to the small heat shock protein (HSP20) family
NX823_03065	COG1309	transcriptional regulator
NX823_03075	COG0456	acetyltransferase
NX823_03085	COG1113	amino acid transport
NX823_03090	COG2318	DinB family
NX823_03095	COG1846	Transcriptional regulator
NX823_03105	COG0778	Nitroreductase
NX823_03110	COG1846	Transcriptional regulator
NX823_03115	COG2814	Major facilitator Superfamily
NX823_03120	COG0730	response to heat
NX823_03125	COG1802	Transcriptional regulator
NX823_03130	COG1388	LysM domain
NX823_03130	COG3858	chitin binding
NX823_03135	COG1819	glycosyl
NX823_03145	COG1785	Belongs to the alkaline phosphatase family
NX823_03150	COG5646	InterPro IPR014922
NX823_03160	COG0454	-acetyltransferase
NX823_03165	COG1078	dGTPase activity
NX823_03170	COG1388	LysM domain
NX823_03175	COG2814	Major facilitator Superfamily
NX823_03180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NX823_03195	COG2723	6-phospho-beta-galactosidase activity
NX823_03200	COG2188	Transcriptional regulator
NX823_03205	COG1940	carbohydrate kinase activity
NX823_03210	COG1482	cell wall glycoprotein biosynthetic process
NX823_03215	COG4124	Belongs to the glycosyl hydrolase 26 family
NX823_03260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NX823_03265	COG0802	atpase or kinase
NX823_03270	COG1214	PFAM Peptidase M22, glycoprotease
NX823_03275	COG0456	acetyltransferase
NX823_03280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NX823_03290	COG0488	(ABC) transporter
NX823_03295	COG0315	cyclic pyranopterin monophosphate synthase activity
NX823_03300	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NX823_03305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NX823_03310	COG0805	protein transport
NX823_03320	COG1266	CAAX protease self-immunity
NX823_03330	COG0459	protein refolding
NX823_03345	COG0457	Tetratricopeptide repeat
NX823_03350	COG1063	alcohol dehydrogenase
NX823_03355	COG2211	Major facilitator Superfamily
NX823_03360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX823_03365	COG1842	Phage shock protein A
NX823_03370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NX823_03375	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NX823_03380	COG4260	virion core protein, lumpy skin disease virus
NX823_03390	COG2814	Major facilitator Superfamily
NX823_03395	COG1063	alcohol dehydrogenase
NX823_03400	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NX823_03405	COG0823	Involved in the tonB-independent uptake of proteins
NX823_03425	COG2267	carboxylic ester hydrolase activity
NX823_03435	COG2132	Multicopper oxidase
NX823_03440	COG1113	amino acid transport
NX823_03450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NX823_03455	COG0714	Associated with various cellular activities
NX823_03460	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NX823_03465	COG1305	Transglutaminase-like
NX823_03470	COG0519	Catalyzes the synthesis of GMP from XMP
NX823_03470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NX823_03485	COG2252	PERMEase
NX823_03490	COG3064	Membrane
NX823_03500	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NX823_03510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NX823_03515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NX823_03520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NX823_03525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NX823_03530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NX823_03535	COG0047	phosphoribosylformylglycinamidine synthase activity
NX823_03540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NX823_03545	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NX823_03550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NX823_03555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NX823_03560	COG0138	bifunctional purine biosynthesis protein purh
NX823_03565	COG0151	Belongs to the GarS family
NX823_03570	COG1522	sequence-specific DNA binding
NX823_03585	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NX823_03590	COG1470	cell adhesion involved in biofilm formation
NX823_03595	COG4496	protein, YerC YecD
NX823_03600	COG0069	glutamate synthase activity
NX823_03605	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NX823_03610	COG0210	DNA helicase
NX823_03615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NX823_03620	COG4851	CamS sex pheromone cAM373 precursor
NX823_03630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NX823_03635	COG1285	pathogenesis
NX823_03640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX823_03645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NX823_03650	COG0154	amidase activity
NX823_03655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NX823_03665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NX823_03670	COG1597	lipid kinase activity
NX823_03675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NX823_03680	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX823_03705	COG5444	nuclease activity
NX823_03715	COG3586	endonuclease activity
NX823_03725	COG0457	Tetratricopeptide repeat
NX823_03735	COG0217	transcriptional regulatory protein
NX823_03745	COG1309	transcriptional regulator
NX823_03750	COG3631	Ketosteroid isomerase-related protein
NX823_03770	COG3546	catalase activity
NX823_03775	COG0454	-acetyltransferase
NX823_03785	COG5578	integral membrane protein
NX823_03790	COG2972	Histidine kinase
NX823_03795	COG2207	Transcriptional regulator
NX823_03795	COG4753	response regulator
NX823_03800	COG1653	transport
NX823_03805	COG1175	transmembrane transport
NX823_03810	COG0395	ABC-type sugar transport system, permease component
NX823_03815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NX823_03820	COG2207	Transcriptional regulator
NX823_03825	COG2755	lipolytic protein G-D-S-L family
NX823_03835	COG5578	integral membrane protein
NX823_03840	COG3401	FG-GAP repeat protein
NX823_03845	COG3401	FG-GAP repeat protein
NX823_03850	COG2755	lipolytic protein G-D-S-L family
NX823_03855	COG1874	Beta-galactosidase
NX823_03865	COG1653	transport
NX823_03870	COG4209	transmembrane transport
NX823_03875	COG0395	ABC-type sugar transport system, permease component
NX823_03880	COG1486	melibiose metabolic process
NX823_03885	COG2323	membrane
NX823_03890	COG2329	Antibiotic biosynthesis monooxygenase
NX823_03895	COG0346	lactoylglutathione lyase activity
NX823_03910	COG5583	Uncharacterized small protein (DUF2292)
NX823_03915	COG0670	Belongs to the BI1 family
NX823_03925	COG1846	Transcriptional regulator
NX823_03930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX823_03940	COG2124	cytochrome p450
NX823_03940	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX823_03945	COG1368	sulfuric ester hydrolase activity
NX823_03950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NX823_03955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX823_03960	COG1442	glycosyl transferase family 8
NX823_03965	COG1216	Glycosyl transferase, family 2
NX823_03970	COG1442	glycosyl transferase family 8
NX823_03975	COG2223	nitrite transmembrane transporter activity
NX823_03980	COG1011	Hydrolase
NX823_03985	COG0531	amino acid
NX823_03990	COG1012	belongs to the aldehyde dehydrogenase family
NX823_03995	COG0840	transmembrane signaling receptor activity
NX823_04000	COG0488	(ABC) transporter
NX823_04010	COG0789	Transcriptional regulator
NX823_04015	COG2814	Major facilitator Superfamily
NX823_04040	COG0488	(ABC) transporter
NX823_04045	COG0513	Belongs to the DEAD box helicase family
NX823_04050	COG0456	acetyltransferase
NX823_04055	COG3328	transposase activity
NX823_04060	COG2130	NADP-dependent
NX823_04065	COG1120	ATPase activity
NX823_04070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX823_04075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX823_04080	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NX823_04095	COG3866	Pectate lyase
NX823_04100	COG0471	metal ion transport
NX823_04105	COG3290	protein histidine kinase activity
NX823_04110	COG4565	transcriptional regulatory protein
NX823_04115	COG3181	Tripartite tricarboxylate transporter family receptor
NX823_04125	COG2851	Citrate transporter
NX823_04130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX823_04135	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NX823_04140	COG1254	Belongs to the acylphosphatase family
NX823_04145	COG2258	MOSC domain
NX823_04165	COG0024	Methionine aminopeptidase
NX823_04170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX823_04170	COG1263	PTS System
NX823_04175	COG1368	sulfuric ester hydrolase activity
NX823_04190	COG1115	amino acid carrier protein
NX823_04205	COG1263	PTS System
NX823_04205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX823_04210	COG0366	Alpha amylase catalytic
NX823_04215	COG2188	Transcriptional regulator
NX823_04220	COG0778	Nitroreductase
NX823_04225	COG0737	Belongs to the 5'-nucleotidase family
NX823_04230	COG0693	protein deglycase activity
NX823_04235	COG2814	Major facilitator Superfamily
NX823_04240	COG4840	Belongs to the UPF0435 family
NX823_04245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NX823_04250	COG4980	gas vesicle protein
NX823_04255	COG1295	ribonuclease BN
NX823_04260	COG0477	Major facilitator Superfamily
NX823_04265	COG0387	Pfam Sodium calcium exchanger
NX823_04275	COG0668	transmembrane transport
NX823_04280	COG0535	radical SAM domain protein
NX823_04290	COG0726	polysaccharide deacetylase
NX823_04295	COG2084	Dehydrogenase
NX823_04300	COG0598	Magnesium transport protein CorA
NX823_04310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NX823_04320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NX823_04325	COG4637	Psort location Cytoplasmic, score
NX823_04335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NX823_04340	COG0022	dehydrogenase e1 component
NX823_04345	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX823_04350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NX823_04355	COG3284	Transcriptional regulator
NX823_04365	COG1742	UPF0060 membrane protein
NX823_04390	COG4842	Belongs to the WXG100 family
NX823_04395	COG1486	melibiose metabolic process
NX823_04405	COG1263	PTS System
NX823_04405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX823_04410	COG5434	Belongs to the glycosyl hydrolase 28 family
NX823_04415	COG1132	(ABC) transporter
NX823_04420	COG1132	(ABC) transporter
NX823_04425	COG2259	Doxx family
NX823_04430	COG2514	catechol 2,3-dioxygenase activity
NX823_04435	COG4977	sequence-specific DNA binding
NX823_04435	COG1917	Cupin 2, conserved barrel domain protein
NX823_04440	COG2814	Major facilitator Superfamily
NX823_04445	COG1082	Xylose isomerase domain protein TIM barrel
NX823_04455	COG4585	Histidine kinase
NX823_04460	COG2197	response regulator
NX823_04465	COG1131	(ABC) transporter
NX823_04470	COG1511	domain protein
NX823_04470	COG0842	Transport permease protein
NX823_04475	COG0842	Transport permease protein
NX823_04480	COG1695	Transcriptional regulator
NX823_04485	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NX823_04490	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NX823_04495	COG1309	transcriptional regulator
NX823_04500	COG2814	Major facilitator Superfamily
NX823_04505	COG2318	DinB family
NX823_04510	COG2814	Major facilitator Superfamily
NX823_04515	COG1846	Transcriptional regulator
NX823_04520	COG0392	lysyltransferase activity
NX823_04520	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NX823_04535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX823_04540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX823_04545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX823_04550	COG0384	phenazine biosynthesis protein PhzF
NX823_04555	COG0778	Nitroreductase
NX823_04570	COG1090	epimerase
NX823_04575	COG2137	regulation of response to DNA damage stimulus
NX823_04585	COG2814	Major facilitator Superfamily
NX823_04600	COG3103	Sh3 type 3 domain protein
NX823_04605	COG5658	integral membrane protein
NX823_04610	COG0596	Alpha beta hydrolase
NX823_04615	COG0463	Glycosyl transferase, family 2
NX823_04620	COG4485	Bacterial membrane protein, YfhO
NX823_04625	COG1988	membrane-bound metal-dependent
NX823_04630	COG1194	a g-specific adenine glycosylase
NX823_04640	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_04655	COG3557	Belongs to the UPF0374 family
NX823_04660	COG1132	(ABC) transporter
NX823_04665	COG4129	membrane
NX823_04670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NX823_04675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NX823_04680	COG0735	belongs to the Fur family
NX823_04790	COG4326	sporulation control protein
NX823_04800	COG5577	PFAM Coat F domain
NX823_04805	COG3340	Belongs to the peptidase S51 family
NX823_04810	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NX823_04820	COG0753	catalase activity
NX823_04825	COG1116	anion transmembrane transporter activity
NX823_04830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NX823_04835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NX823_04840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX823_04850	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NX823_04860	COG1476	TRANSCRIPTIONal
NX823_04870	COG3382	B3 4 domain protein
NX823_04875	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NX823_04885	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NX823_04890	COG0789	Transcriptional regulator
NX823_04895	COG1664	Polymer-forming cytoskeletal
NX823_04900	COG1664	Polymer-forming cytoskeletal
NX823_04905	COG2766	serine protein kinase
NX823_04910	COG2718	Belongs to the UPF0229 family
NX823_04915	COG1846	Transcriptional regulator
NX823_04920	COG1566	PFAM secretion protein HlyD family protein
NX823_04925	COG2814	Major facilitator Superfamily
NX823_04930	COG0655	NAD(P)H dehydrogenase (quinone) activity
NX823_04950	COG1725	Transcriptional regulator
NX823_04955	COG1131	(ABC) transporter
NX823_04960	COG1131	(ABC) transporter
NX823_04965	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NX823_04970	COG1278	Cold shock
NX823_04975	COG1464	Belongs to the NlpA lipoprotein family
NX823_04985	COG1823	symporter activity
NX823_04990	COG5444	nuclease activity
NX823_05015	COG0582	viral genome integration into host DNA
NX823_05080	COG5644	endopeptidase inhibitor activity
NX823_05085	COG0741	lytic transglycosylase activity
NX823_05085	COG0791	NLP P60 protein
NX823_05105	COG0457	Tetratricopeptide repeat
NX823_05125	COG1525	nuclease
NX823_05125	COG4085	toxin activity
NX823_05125	COG0737	Belongs to the 5'-nucleotidase family
NX823_05130	COG3764	Sortase (surface protein transpeptidase)
NX823_05135	COG0564	pseudouridine synthase activity
NX823_05145	COG0517	IMP dehydrogenase activity
NX823_05150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NX823_05155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NX823_05155	COG3153	acetyltransferase
NX823_05165	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NX823_05170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NX823_05175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NX823_05180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NX823_05185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NX823_05190	COG2203	Gaf domain
NX823_05190	COG4585	Histidine kinase
NX823_05195	COG2197	response regulator
NX823_05200	COG0431	NADPH-dependent FMN reductase
NX823_05215	COG1388	LysM domain
NX823_05215	COG0791	NLP P60 protein
NX823_05220	COG1959	2 iron, 2 sulfur cluster binding
NX823_05225	COG0668	transmembrane transport
NX823_05230	COG2719	SpoVR family
NX823_05235	COG1785	Belongs to the alkaline phosphatase family
NX823_05240	COG0791	NLP P60 protein
NX823_05240	COG1388	LysM domain
NX823_05245	COG0583	DNA-binding transcription factor activity
NX823_05250	COG0372	Belongs to the citrate synthase family
NX823_05255	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_05260	COG0531	amino acid
NX823_05265	COG0733	neurotransmitter:sodium symporter activity
NX823_05270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX823_05275	COG0456	acetyltransferase
NX823_05290	COG1595	DNA-templated transcription, initiation
NX823_05295	COG0667	Aldo Keto reductase
NX823_05300	COG0204	Acyl-transferase
NX823_05305	COG1253	flavin adenine dinucleotide binding
NX823_05310	COG0789	Transcriptional regulator
NX823_05320	COG1253	flavin adenine dinucleotide binding
NX823_05325	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NX823_05330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NX823_05335	COG0584	glycerophosphoryl diester phosphodiesterase
NX823_05345	COG0668	transmembrane transport
NX823_05350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NX823_05355	COG0726	polysaccharide deacetylase
NX823_05360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX823_05365	COG1757	Na H antiporter
NX823_05370	COG0589	response to stress
NX823_05380	COG1132	(ABC) transporter
NX823_05385	COG1132	(ABC) transporter
NX823_05390	COG0702	epimerase
NX823_05410	COG0189	ligase activity
NX823_05415	COG0189	ligase activity
NX823_05420	COG4399	Belongs to the UPF0754 family
NX823_05425	COG3679	Belongs to the UPF0342 family
NX823_05430	COG4335	DNA alkylation repair
NX823_05435	COG0561	phosphatase activity
NX823_05440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NX823_05450	COG0475	glutathione-regulated potassium exporter activity
NX823_05455	COG0490	domain, Protein
NX823_05465	COG1024	Enoyl-CoA hydratase
NX823_05475	COG4152	abc transporter atp-binding protein
NX823_05480	COG1668	transmembrane transport
NX823_05485	COG0420	3'-5' exonuclease activity
NX823_05490	COG4717	serine-type aminopeptidase activity
NX823_05495	COG3481	metal-dependent phosphohydrolase, HD sub domain
NX823_05505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NX823_05535	COG1846	Transcriptional regulator
NX823_05540	COG4980	gas vesicle protein
NX823_05555	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NX823_05560	COG0537	adenosine 5'-monophosphoramidase activity
NX823_05565	COG1131	(ABC) transporter
NX823_05570	COG4473	ABC transporter
NX823_05585	COG3069	C4-dicarboxylate transmembrane transporter activity
NX823_05595	COG2329	Antibiotic biosynthesis monooxygenase
NX823_05600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NX823_05605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NX823_05610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NX823_05615	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NX823_05620	COG1309	transcriptional regulator
NX823_05625	COG1511	domain protein
NX823_05630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX823_05635	COG4377	Putative membrane peptidase family (DUF2324)
NX823_05645	COG1363	Peptidase, m42
NX823_05650	COG4405	Protein conserved in bacteria
NX823_05655	COG1301	dicarboxylic acid transport
NX823_05665	COG1234	tRNA 3'-trailer cleavage
NX823_05670	COG0095	Lipoate-protein ligase
NX823_05675	COG0702	epimerase
NX823_05680	COG0318	PFAM AMP-dependent synthetase and ligase
NX823_05695	COG0501	Belongs to the peptidase M48B family
NX823_05705	COG0456	acetyltransferase
NX823_05710	COG0604	alcohol dehydrogenase
NX823_05715	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NX823_05725	COG0406	alpha-ribazole phosphatase activity
NX823_05730	COG0183	Belongs to the thiolase family
NX823_05735	COG0318	PFAM AMP-dependent synthetase and ligase
NX823_05740	COG1268	BioY protein
NX823_05745	COG0840	transmembrane signaling receptor activity
NX823_05755	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_05765	COG4903	ComK protein
NX823_05770	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_05780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX823_05795	COG0398	Pfam SNARE associated Golgi protein
NX823_05800	COG0681	Belongs to the peptidase S26 family
NX823_05805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX823_05810	COG1846	Transcriptional regulator
NX823_05820	COG0738	Major facilitator superfamily
NX823_05825	COG0673	inositol 2-dehydrogenase activity
NX823_05830	COG0561	phosphatase activity
NX823_05835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NX823_05840	COG1609	Transcriptional regulator
NX823_05845	COG3180	Ammonia monooxygenase
NX823_05850	COG0477	Major facilitator Superfamily
NX823_05850	COG2814	Major facilitator Superfamily
NX823_05855	COG4533	DNA binding
NX823_05865	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NX823_05870	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NX823_05875	COG1074	ATP-dependent DNA helicase activity
NX823_05880	COG0420	3'-5' exonuclease activity
NX823_05885	COG0419	ATPase involved in DNA repair
NX823_05890	COG1403	HNH endonuclease
NX823_05930	COG5337	Spore coat protein CotH
NX823_05935	COG0179	Fumarylacetoacetate (FAA) hydrolase
NX823_05945	COG1404	Belongs to the peptidase S8 family
NX823_05960	COG0367	asparagine synthase
NX823_05970	COG0534	Mate efflux family protein
NX823_05975	COG2207	Transcriptional regulator
NX823_05975	COG1917	Cupin 2, conserved barrel domain protein
NX823_05980	COG1609	Transcriptional regulator
NX823_05985	COG0673	inositol 2-dehydrogenase activity
NX823_05990	COG2318	DinB family
NX823_06000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX823_06005	COG1357	PFAM Pentapeptide repeats (8 copies)
NX823_06010	COG2267	carboxylic ester hydrolase activity
NX823_06015	COG0529	Catalyzes the synthesis of activated sulfate
NX823_06025	COG0175	sulfate reduction
NX823_06030	COG2045	Belongs to the ComB family
NX823_06035	COG1809	phosphosulfolactate synthase activity
NX823_06040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX823_06050	COG2814	Major facilitator Superfamily
NX823_06055	COG0454	-acetyltransferase
NX823_06060	COG2153	protein acetylation
NX823_06065	COG0646	methionine synthase
NX823_06065	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NX823_06070	COG1666	GTP binding
NX823_06075	COG2996	Protein conserved in bacteria
NX823_06090	COG1307	EDD domain protein, DegV family
NX823_06095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX823_06115	COG0561	phosphatase activity
NX823_06120	COG1073	alpha beta
NX823_06125	COG2151	metal-sulfur cluster biosynthetic enzyme
NX823_06140	COG2271	Major facilitator Superfamily
NX823_06145	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NX823_06150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NX823_06160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NX823_06165	COG0505	Belongs to the CarA family
NX823_06170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NX823_06175	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NX823_06195	COG2267	carboxylic ester hydrolase activity
NX823_06205	COG1744	ABC transporter substrate-binding protein PnrA-like
NX823_06220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX823_06225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NX823_06230	COG5504	Zn-dependent protease
NX823_06235	COG0444	Belongs to the ABC transporter superfamily
NX823_06240	COG4608	Belongs to the ABC transporter superfamily
NX823_06250	COG0601	transmembrane transport
NX823_06255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NX823_06265	COG0180	Tryptophanyl-tRNA synthetase
NX823_06270	COG4166	transmembrane transport
NX823_06275	COG0601	transmembrane transport
NX823_06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NX823_06285	COG0444	Belongs to the ABC transporter superfamily
NX823_06290	COG4608	Belongs to the ABC transporter superfamily
NX823_06295	COG2814	Major facilitator Superfamily
NX823_06300	COG0456	acetyltransferase
NX823_06305	COG1393	Belongs to the ArsC family
NX823_06310	COG0861	Integral membrane protein TerC family
NX823_06320	COG4862	establishment of competence for transformation
NX823_06330	COG4469	Competence protein
NX823_06335	COG1164	Oligoendopeptidase f
NX823_06345	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NX823_06350	COG2346	COG2346, Truncated hemoglobins
NX823_06355	COG0741	lytic transglycosylase activity
NX823_06360	COG4116	CYTH
NX823_06370	COG2357	RelA SpoT domain protein
NX823_06375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NX823_06380	COG0564	pseudouridine synthase activity
NX823_06385	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NX823_06390	COG0475	glutathione-regulated potassium exporter activity
NX823_06390	COG0569	domain protein
NX823_06395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NX823_06400	COG0352	thiamine-phosphate diphosphorylase activity
NX823_06405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX823_06410	COG2104	thiamine diphosphate biosynthetic process
NX823_06415	COG2022	thiamine diphosphate biosynthetic process
NX823_06420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NX823_06425	COG0351	phosphomethylpyrimidine kinase
NX823_06430	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NX823_06485	COG0210	DNA helicase
NX823_06495	COG2153	protein acetylation
NX823_06500	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NX823_06505	COG2382	esterase
NX823_06510	COG0626	cystathionine gamma-synthase activity
NX823_06515	COG0626	cystathionine gamma-synthase activity
NX823_06520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX823_06525	COG5505	Protein of unknown function (DUF819)
NX823_06565	COG1396	sequence-specific DNA binding
NX823_06650	COG0457	Tetratricopeptide repeat
NX823_06655	COG5444	nuclease activity
NX823_06670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX823_06680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NX823_06695	COG0109	protoheme IX farnesyltransferase activity
NX823_06705	COG0726	polysaccharide deacetylase
NX823_06720	COG5504	Zn-dependent protease
NX823_06725	COG2205	protein histidine kinase activity
NX823_06735	COG3383	formate dehydrogenase (NAD+) activity
NX823_06750	COG1051	belongs to the nudix hydrolase family
NX823_06760	COG2124	cytochrome p450
NX823_06765	COG1819	glycosyl
NX823_06775	COG1587	Uroporphyrinogen-III synthase
NX823_06780	COG0390	transport system, permease component
NX823_06785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NX823_06790	COG0697	spore germination
NX823_06805	COG1252	NADH dehydrogenase
NX823_06810	COG1904	glucuronate isomerase
NX823_06820	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NX823_06825	COG1063	alcohol dehydrogenase
NX823_06830	COG1312	Catalyzes the dehydration of D-mannonate
NX823_06835	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_06840	COG2271	Major facilitator Superfamily
NX823_06845	COG1609	Transcriptional regulator
NX823_06850	COG0246	Mannitol dehydrogenase
NX823_06855	COG2721	sulfolactate sulfo-lyase activity
NX823_06860	COG0730	response to heat
NX823_06870	COG2318	DinB family
NX823_06890	COG0457	Tetratricopeptide repeat
NX823_06905	COG1388	LysM domain
NX823_06905	COG3409	Peptidoglycan-binding domain 1 protein
NX823_06905	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX823_06915	COG4195	phage-related replication protein
NX823_06920	COG3546	catalase activity
NX823_06925	COG2856	Zn peptidase
NX823_06930	COG1396	sequence-specific DNA binding
NX823_06940	COG1522	sequence-specific DNA binding
NX823_06945	COG1484	DNA-dependent DNA replication
NX823_06965	COG1595	DNA-templated transcription, initiation
NX823_06970	COG3728	DNA packaging
NX823_06970	COG5484	DNA packaging
NX823_06975	COG1783	phage Terminase large subunit
NX823_06980	COG5518	Phage portal protein
NX823_06985	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NX823_06990	COG4653	Phage capsid family
NX823_07040	COG5412	phage tail tape measure protein
NX823_07040	COG3953	SLT domain
NX823_07040	COG5412	phage tail tape measure protein
NX823_07040	COG3953	SLT domain
NX823_07040	COG5412	phage tail tape measure protein
NX823_07040	COG3953	SLT domain
NX823_07045	COG1652	LysM domain
NX823_07050	COG4193	domain, Protein
NX823_07060	COG3628	GPW Gp25 family protein
NX823_07065	COG3299	homolog of phage Mu protein gp47
NX823_07070	COG3778	Protein conserved in bacteria
NX823_07110	COG3409	Peptidoglycan-binding domain 1 protein
NX823_07110	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX823_07130	COG0306	phosphate transporter
NX823_07135	COG1392	Phosphate transport regulator
NX823_07140	COG0531	amino acid
NX823_07145	COG0346	lactoylglutathione lyase activity
NX823_07155	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NX823_07160	COG0463	Glycosyl transferase, family 2
NX823_07165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX823_07170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NX823_07175	COG2362	D-Aminopeptidase
NX823_07180	COG0601	transmembrane transport
NX823_07185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NX823_07190	COG0444	Belongs to the ABC transporter superfamily
NX823_07195	COG4166	transmembrane transport
NX823_07200	COG1619	proteins homologs of microcin C7 resistance protein MccF
NX823_07205	COG4948	Mandelate Racemase Muconate Lactonizing
NX823_07210	COG0791	NLP P60 protein
NX823_07215	COG4608	Belongs to the ABC transporter superfamily
NX823_07220	COG2706	6-phosphogluconolactonase activity
NX823_07230	COG1607	acyl-coa hydrolase
NX823_07235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NX823_07235	COG1017	nitric oxide dioxygenase activity
NX823_07245	COG2323	membrane
NX823_07250	COG2318	DinB family
NX823_07255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX823_07260	COG2076	Multidrug Resistance protein
NX823_07265	COG2076	Multidrug Resistance protein
NX823_07270	COG0788	formyltetrahydrofolate deformylase activity
NX823_07275	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NX823_07280	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NX823_07285	COG1764	response to oxidative stress
NX823_07290	COG1846	Transcriptional regulator
NX823_07295	COG1764	response to oxidative stress
NX823_07305	COG0590	tRNA wobble adenosine to inosine editing
NX823_07310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NX823_07315	COG1404	Belongs to the peptidase S8 family
NX823_07320	COG1366	Belongs to the anti-sigma-factor antagonist family
NX823_07325	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NX823_07330	COG1122	ATPase activity
NX823_07335	COG4721	ABC-type cobalt transport system, permease component
NX823_07345	COG0745	RESPONSE REGULATOR receiver
NX823_07350	COG3850	Histidine kinase
NX823_07350	COG5002	protein histidine kinase activity
NX823_07355	COG3212	peptidase
NX823_07360	COG3212	peptidase
NX823_07375	COG2239	Acts as a magnesium transporter
NX823_07380	COG0789	Transcriptional regulator
NX823_07395	COG1846	Transcriptional regulator
NX823_07400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NX823_07405	COG0726	polysaccharide deacetylase
NX823_07420	COG0463	Glycosyl transferase, family 2
NX823_07425	COG3285	dna ligase
NX823_07425	COG1793	dna ligase
NX823_07430	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NX823_07435	COG5001	Diguanylate cyclase
NX823_07435	COG3300	MHYT domain
NX823_07440	COG0586	Pfam SNARE associated Golgi protein
NX823_07445	COG0861	Integral membrane protein TerC family
NX823_07450	COG1191	sigma factor activity
NX823_07470	COG0501	Belongs to the peptidase M48B family
NX823_07475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NX823_07490	COG3594	Acyltransferase
NX823_07495	COG5002	protein histidine kinase activity
NX823_07500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NX823_07510	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NX823_07515	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NX823_07520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NX823_07525	COG0436	Aminotransferase
NX823_07530	COG1850	ribulose-bisphosphate carboxylase activity
NX823_07535	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NX823_07540	COG0235	Class ii aldolase
NX823_07545	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NX823_07550	COG3339	Conserved Protein
NX823_07565	COG3852	Histidine kinase
NX823_07570	COG1846	Transcriptional regulator
NX823_07575	COG1360	Flagellar Motor Protein
NX823_07580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NX823_07585	COG0542	response to heat
NX823_07590	COG3949	Membrane
NX823_07595	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NX823_07600	COG0720	synthase
NX823_07605	COG0602	queuosine metabolic process
NX823_07610	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NX823_07620	COG4873	Protein conserved in bacteria
NX823_07630	COG3773	Cell wall hydrolase
NX823_07635	COG2244	polysaccharide biosynthetic process
NX823_07640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX823_07645	COG2217	Heavy metal translocating P-type atpase
NX823_07655	COG0006	proline dipeptidase activity
NX823_07660	COG1609	Transcriptional regulator
NX823_07665	COG3711	transcriptional antiterminator
NX823_07670	COG2190	(PTS) system
NX823_07670	COG1263	PTS System
NX823_07670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX823_07675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX823_07680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NX823_07690	COG1533	DNA photolyase activity
NX823_07695	COG0456	acetyltransferase
NX823_07700	COG0840	transmembrane signaling receptor activity
NX823_07705	COG2084	Dehydrogenase
NX823_07710	COG2340	Cysteine-rich secretory protein family
NX823_07715	COG0768	penicillin binding
NX823_07720	COG4191	Histidine kinase
NX823_07725	COG0436	Aminotransferase
NX823_07735	COG0784	Response regulator, receiver
NX823_07735	COG0835	chemotaxis
NX823_07745	COG2814	Major facilitator Superfamily
NX823_07750	COG1376	ErfK ybiS ycfS ynhG family protein
NX823_07755	COG1408	metallophosphoesterase
NX823_07760	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_07765	COG2200	EAL domain
NX823_07770	COG4703	Protein of unknown function (DUF1797)
NX823_07775	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NX823_07785	COG0517	IMP dehydrogenase activity
NX823_07790	COG0583	DNA-binding transcription factor activity
NX823_07795	COG0716	FMN binding
NX823_07805	COG0716	FMN binding
NX823_07810	COG2171	N-acyltransferase activity
NX823_07815	COG1473	amidohydrolase
NX823_07825	COG0668	transmembrane transport
NX823_07830	COG0450	alkyl hydroperoxide reductase
NX823_07835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX823_07855	COG0746	molybdenum cofactor guanylyltransferase activity
NX823_07860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NX823_07865	COG0303	'Molybdopterin
NX823_07870	COG1763	Mo-molybdopterin cofactor biosynthetic process
NX823_07875	COG0314	molybdopterin synthase activity
NX823_07880	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NX823_07885	COG1132	(ABC) transporter
NX823_07890	COG1132	(ABC) transporter
NX823_07900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX823_07905	COG1136	(ABC) transporter
NX823_07910	COG0577	efflux transmembrane transporter activity
NX823_07915	COG1349	DNA-binding transcription factor activity
NX823_07920	COG1105	Belongs to the carbohydrate kinase PfkB family
NX823_07925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX823_07925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NX823_07925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NX823_07930	COG0681	Belongs to the peptidase S26 family
NX823_07940	COG0488	(ABC) transporter
NX823_07945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NX823_07950	COG2309	aminopeptidase activity
NX823_07960	COG1077	Cell shape determining protein MreB Mrl
NX823_07965	COG2002	toxin-antitoxin pair type II binding
NX823_07970	COG3852	Histidine kinase
NX823_07975	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NX823_07975	COG2105	PFAM AIG2 family protein
NX823_07980	COG0569	domain protein
NX823_07985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NX823_07995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NX823_08000	COG5503	Protein of unknown function (DUF1447)
NX823_08005	COG0561	phosphatase activity
NX823_08010	COG0242	peptide deformylase activity
NX823_08020	COG0497	DNA recombination
NX823_08025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NX823_08030	COG0022	dehydrogenase e1 component
NX823_08035	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX823_08040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NX823_08045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX823_08055	COG1982	Orn Lys Arg decarboxylase major
NX823_08060	COG4476	Belongs to the UPF0223 family
NX823_08065	COG4493	Belongs to the UPF0637 family
NX823_08075	COG0483	inositol monophosphate 1-phosphatase activity
NX823_08085	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NX823_08105	COG1595	DNA-templated transcription, initiation
NX823_08125	COG1217	gtp-binding protein TYPA
NX823_08135	COG4896	Protein conserved in bacteria
NX823_08145	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NX823_08150	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NX823_08155	COG2066	Belongs to the glutaminase family
NX823_08160	COG4838	Belongs to the UPF0358 family
NX823_08165	COG0772	Belongs to the SEDS family
NX823_08170	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NX823_08175	COG1612	heme a metabolic process
NX823_08180	COG0109	protoheme IX farnesyltransferase activity
NX823_08185	COG2010	Cytochrome c
NX823_08185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NX823_08190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NX823_08195	COG1845	cytochrome c oxidase, subunit III
NX823_08200	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NX823_08205	COG3336	cytochrome c oxidase
NX823_08215	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NX823_08220	COG2340	Cysteine-rich secretory protein family
NX823_08235	COG3679	Belongs to the UPF0342 family
NX823_08240	COG4471	UPF0298 protein
NX823_08245	COG0742	ribosomal rna small subunit methyltransferase
NX823_08250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NX823_08255	COG3314	Sporulation integral membrane protein YlbJ
NX823_08260	COG1752	Esterase of the alpha-beta hydrolase superfamily
NX823_08265	COG3480	Lon protease (S16) C-terminal proteolytic domain
NX823_08270	COG1323	Belongs to the UPF0348 family
NX823_08280	COG1399	metal-binding, possibly nucleic acid-binding protein
NX823_08295	COG0454	-acetyltransferase
NX823_08300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NX823_08305	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NX823_08310	COG2001	Belongs to the MraZ family
NX823_08315	COG0275	rRNA processing
NX823_08320	COG4839	cell division protein FtsL
NX823_08325	COG0768	penicillin binding
NX823_08330	COG0768	penicillin binding
NX823_08335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NX823_08340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NX823_08345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NX823_08350	COG0772	Belongs to the SEDS family
NX823_08355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NX823_08360	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NX823_08365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NX823_08370	COG3879	Bacterial protein of unknown function (DUF881)
NX823_08375	COG3879	Bacterial protein of unknown function (DUF881)
NX823_08380	COG3856	small basic protein
NX823_08385	COG0849	cell division
NX823_08390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NX823_08395	COG1404	Belongs to the peptidase S8 family
NX823_08395	COG4412	M6 family metalloprotease domain protein
NX823_08405	COG1191	sigma factor activity
NX823_08410	COG1191	sigma factor activity
NX823_08415	COG1119	ATPase activity
NX823_08420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX823_08425	COG1873	PFAM PRC-barrel domain
NX823_08430	COG1496	oxidoreductase activity
NX823_08435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NX823_08440	COG1799	cell septum assembly
NX823_08445	COG0762	integral membrane protein
NX823_08450	COG2302	S4 RNA-binding domain
NX823_08455	COG3599	regulation of cell shape
NX823_08460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NX823_08465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX823_08470	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NX823_08475	COG0564	pseudouridine synthase activity
NX823_08480	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NX823_08485	COG2233	PERMEase
NX823_08490	COG0540	Belongs to the ATCase OTCase family
NX823_08495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NX823_08500	COG0505	Belongs to the CarA family
NX823_08505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NX823_08510	COG0543	2 iron, 2 sulfur cluster binding
NX823_08515	COG0167	dihydroorotate dehydrogenase activity
NX823_08520	COG0284	orotidine-5'-phosphate decarboxylase activity
NX823_08525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NX823_08530	COG0175	sulfate reduction
NX823_08535	COG0306	phosphate transporter
NX823_08540	COG2046	Belongs to the sulfate adenylyltransferase family
NX823_08545	COG0529	Catalyzes the synthesis of activated sulfate
NX823_08550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NX823_08555	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NX823_08560	COG1648	precorrin-2 dehydrogenase activity
NX823_08565	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NX823_08570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NX823_08575	COG1561	YicC-like family, N-terminal region
NX823_08585	COG0194	GDP metabolic process
NX823_08590	COG1758	RNA polymerase activity
NX823_08595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NX823_08600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NX823_08605	COG0242	peptide deformylase activity
NX823_08610	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NX823_08615	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NX823_08615	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NX823_08620	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NX823_08625	COG0631	protein serine/threonine phosphatase activity
NX823_08630	COG0515	serine threonine protein kinase
NX823_08630	COG2815	serine threonine protein kinase
NX823_08635	COG1162	GTPase activity
NX823_08640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NX823_08645	COG1564	THIamine pyrophosphokinase
NX823_08655	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NX823_08660	COG1302	Protein conserved in bacteria
NX823_08665	COG1461	Dihydroxyacetone kinase
NX823_08670	COG1760	l-serine dehydratase
NX823_08675	COG1760	l-serine dehydratase
NX823_08680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NX823_08685	COG2050	protein possibly involved in aromatic compounds catabolism
NX823_08685	COG1349	DNA-binding transcription factor activity
NX823_08690	COG0416	fatty acid biosynthetic process
NX823_08695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NX823_08700	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_08710	COG0571	ribonuclease III activity
NX823_08715	COG1196	nuclear chromosome segregation
NX823_08720	COG0552	protein localization to endoplasmic reticulum
NX823_08735	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NX823_08740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NX823_08745	COG0228	four-way junction DNA binding
NX823_08750	COG1837	Belongs to the UPF0109 family
NX823_08760	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NX823_08765	COG0336	Belongs to the RNA methyltransferase TrmD family
NX823_08770	COG0335	large ribosomal subunit rRNA binding
NX823_08775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NX823_08780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NX823_08790	COG2257	FlhB HrpN YscU SpaS Family
NX823_08795	COG0045	succinate-CoA ligase (ADP-forming) activity
NX823_08800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NX823_08805	COG0758	DNA mediated transformation
NX823_08810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NX823_08815	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NX823_08820	COG4974	Belongs to the 'phage' integrase family
NX823_08825	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NX823_08830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NX823_08835	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NX823_08840	COG1815	bacterial-type flagellum-dependent cell motility
NX823_08845	COG1558	bacterial-type flagellum-dependent cell motility
NX823_08850	COG1677	Flagellar hook-basal body complex protein FliE
NX823_08855	COG1766	The M ring may be actively involved in energy transduction
NX823_08860	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NX823_08865	COG1317	bacterial-type flagellum organization
NX823_08870	COG1157	protein secretion by the type III secretion system
NX823_08875	COG2882	bacterial-type flagellum organization
NX823_08880	COG3334	PFAM MgtE intracellular
NX823_08885	COG3144	bacterial-type flagellum assembly
NX823_08890	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NX823_08895	COG4786	Flagellar basal body rod
NX823_08900	COG1582	Flagellar protein (FlbD)
NX823_08905	COG1580	Controls the rotational direction of flagella during chemotaxis
NX823_08910	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NX823_08915	COG1776	CheC inhibitor of MCP methylation
NX823_08915	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NX823_08920	COG2201	protein-glutamate methylesterase activity
NX823_08925	COG3190	flagellar
NX823_08930	COG1338	Plays a role in the flagellum-specific transport system
NX823_08935	COG1987	bacterial-type flagellum assembly
NX823_08940	COG1684	flagellar biosynthetic protein fliR
NX823_08945	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NX823_08950	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NX823_08955	COG1419	protein localization to endoplasmic reticulum
NX823_08960	COG0455	bacterial-type flagellum organization
NX823_08965	COG2201	protein-glutamate methylesterase activity
NX823_08970	COG2198	Histidine kinase
NX823_08970	COG0643	Histidine kinase
NX823_08975	COG0835	chemotaxis
NX823_08980	COG1776	CheC inhibitor of MCP methylation
NX823_08985	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NX823_08990	COG1191	sigma factor activity
NX823_09000	COG0052	Belongs to the universal ribosomal protein uS2 family
NX823_09005	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NX823_09010	COG0528	UMP kinase activity
NX823_09015	COG0233	cytoplasmic translational termination
NX823_09020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NX823_09025	COG4589	Belongs to the CDS family
NX823_09030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NX823_09035	COG0750	zinc metalloprotease
NX823_09040	COG0442	prolyl-tRNA aminoacylation
NX823_09045	COG2176	DNA-directed DNA polymerase activity
NX823_09050	COG0779	Required for maturation of 30S ribosomal subunits
NX823_09055	COG0195	Participates in both transcription termination and antitermination
NX823_09060	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NX823_09065	COG1358	cellular component organization or biogenesis
NX823_09070	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NX823_09075	COG1550	Protein conserved in bacteria
NX823_09080	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NX823_09085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NX823_09090	COG0196	riboflavin kinase activity
NX823_09095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NX823_09100	COG1185	polyribonucleotide nucleotidyltransferase activity
NX823_09105	COG0726	polysaccharide deacetylase
NX823_09110	COG0612	Peptidase, M16
NX823_09115	COG1873	PFAM PRC-barrel domain
NX823_09120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NX823_09125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NX823_09130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NX823_09135	COG0527	aspartate kinase activity
NX823_09140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NX823_09145	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NX823_09150	COG0740	serine-type endopeptidase activity
NX823_09160	COG1674	ftsk spoiiie
NX823_09160	COG4980	gas vesicle protein
NX823_09165	COG2188	Transcriptional regulator
NX823_09170	COG2814	Major facilitator Superfamily
NX823_09175	COG0612	Peptidase, M16
NX823_09180	COG0612	Peptidase, M16
NX823_09185	COG0300	oxidoreductase activity
NX823_09200	COG1426	Protein conserved in bacteria
NX823_09205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NX823_09210	COG1546	Belongs to the CinA family
NX823_09210	COG1058	Belongs to the CinA family
NX823_09215	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NX823_09220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NX823_09225	COG1418	mRNA catabolic process
NX823_09230	COG1692	metallophosphoesterase
NX823_09235	COG2359	stage V sporulation protein S
NX823_09240	COG1063	alcohol dehydrogenase
NX823_09245	COG0156	8-amino-7-oxononanoate synthase activity
NX823_09250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NX823_09255	COG4550	Control of competence regulator ComK, YlbF/YmcA
NX823_09265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NX823_09270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NX823_09360	COG3328	transposase activity
NX823_09375	COG3226	Transcriptional regulator
NX823_09385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX823_09390	COG1404	Belongs to the peptidase S8 family
NX823_09400	COG4195	phage-related replication protein
NX823_09405	COG1764	response to oxidative stress
NX823_09410	COG2076	Multidrug Resistance protein
NX823_09415	COG2076	Multidrug Resistance protein
NX823_09430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NX823_09435	COG1923	regulation of RNA biosynthetic process
NX823_09450	COG1780	Probably involved in ribonucleotide reductase function
NX823_09455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NX823_09460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NX823_09465	COG4112	unkown
NX823_09470	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX823_09475	COG0464	growth
NX823_09480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NX823_09485	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NX823_09490	COG0789	Transcriptional regulator
NX823_09495	COG0174	glutamine synthetase
NX823_09545	COG4282	regulation of fungal-type cell wall biogenesis
NX823_09555	COG3328	transposase activity
NX823_09560	COG1525	nuclease
NX823_09565	COG2814	Major facilitator Superfamily
NX823_09570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NX823_09585	COG0756	dUTP diphosphatase activity
NX823_09625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NX823_09645	COG3832	glyoxalase III activity
NX823_09685	COG4195	phage-related replication protein
NX823_09695	COG0346	lactoylglutathione lyase activity
NX823_09705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NX823_09710	COG1388	LysM domain
NX823_09715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX823_09720	COG4224	UPF0291 protein
NX823_09725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NX823_09735	COG3763	UPF0154 protein
NX823_09745	COG0785	Cytochrome C biogenesis protein
NX823_09750	COG2201	protein-glutamate methylesterase activity
NX823_09755	COG4846	Membrane protein involved in cytochrome C biogenesis
NX823_09765	COG0071	Belongs to the small heat shock protein (HSP20) family
NX823_09780	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NX823_09785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX823_09805	COG0824	Thioesterase
NX823_09815	COG4841	protein insertion into membrane
NX823_09820	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NX823_09825	COG1832	CoA-binding protein
NX823_09830	COG0187	DNA topoisomerase II activity
NX823_09835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NX823_09850	COG1115	amino acid carrier protein
NX823_09855	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX823_09865	COG5520	Belongs to the glycosyl hydrolase 30 family
NX823_09875	COG2246	polysaccharide biosynthetic process
NX823_09880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NX823_09885	COG0586	Pfam SNARE associated Golgi protein
NX823_09890	COG2404	hydrolase activity, acting on ester bonds
NX823_09895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NX823_09900	COG1024	Enoyl-CoA hydratase
NX823_09905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NX823_09910	COG0511	ligase activity, forming carbon-carbon bonds
NX823_09920	COG0318	PFAM AMP-dependent synthetase and ligase
NX823_09925	COG1960	acyl-CoA dehydrogenase activity
NX823_09940	COG1649	PFAM Uncharacterised BCR, COG1649
NX823_09955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX823_09960	COG2027	D-alanyl-D-alanine carboxypeptidase
NX823_09965	COG2017	converts alpha-aldose to the beta-anomer
NX823_09970	COG0534	Mate efflux family protein
NX823_09985	COG0582	viral genome integration into host DNA
NX823_09990	COG0166	Belongs to the GPI family
NX823_09995	COG0405	Gamma-glutamyltransferase
NX823_10000	COG0583	DNA-binding transcription factor activity
NX823_10005	COG0604	alcohol dehydrogenase
NX823_10010	COG0493	'glutamate synthase
NX823_10015	COG0069	glutamate synthase activity
NX823_10015	COG0067	glutamate synthase
NX823_10015	COG0070	glutamate synthase
NX823_10020	COG0583	DNA-binding transcription factor activity
NX823_10050	COG0300	oxidoreductase activity
NX823_10055	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NX823_10065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX823_10080	COG1131	(ABC) transporter
NX823_10090	COG2814	Major facilitator Superfamily
NX823_10100	COG2323	membrane
NX823_10115	COG2323	membrane
NX823_10130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX823_10150	COG3546	catalase activity
NX823_10170	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX823_10190	COG2368	4-hydroxyphenylacetate
NX823_10200	COG3619	membrane
NX823_10250	COG2720	vancomycin resistance protein
NX823_10265	COG3739	integral membrane protein
NX823_10270	COG0583	DNA-binding transcription factor activity
NX823_10275	COG0697	spore germination
NX823_10285	COG0693	protein deglycase activity
NX823_10290	COG2367	Beta-lactamase
NX823_10310	COG0574	Belongs to the PEP-utilizing enzyme family
NX823_10310	COG3848	Pyruvate phosphate dikinase
NX823_10315	COG0726	polysaccharide deacetylase
NX823_10325	COG2314	TM2 domain
NX823_10330	COG1396	sequence-specific DNA binding
NX823_10440	COG0457	Tetratricopeptide repeat
NX823_10445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX823_10450	COG3328	transposase activity
NX823_10470	COG3328	transposase activity
NX823_10485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX823_10505	COG5444	nuclease activity
NX823_10510	COG4282	regulation of fungal-type cell wall biogenesis
NX823_10515	COG1231	oxidoreductase activity
NX823_10520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX823_10525	COG0662	Cupin 2, conserved barrel domain protein
NX823_10525	COG2207	Transcriptional regulator
NX823_10530	COG0456	acetyltransferase
NX823_10535	COG1309	transcriptional regulator
NX823_10540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX823_10545	COG3708	Transcriptional regulator
NX823_10550	COG2378	regulation of single-species biofilm formation
NX823_10560	COG0640	Transcriptional regulator
NX823_10565	COG0741	lytic transglycosylase activity
NX823_10570	COG2322	membrane
NX823_10585	COG1619	proteins homologs of microcin C7 resistance protein MccF
NX823_10590	COG3239	Fatty acid desaturase
NX823_10595	COG4585	Histidine kinase
NX823_10600	COG2197	response regulator
NX823_10605	COG1388	LysM domain
NX823_10605	COG3584	3D domain protein
NX823_10610	COG0514	ATP-dependent DNA helicase (RecQ)
NX823_10620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NX823_10625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX823_10640	COG0071	Belongs to the small heat shock protein (HSP20) family
NX823_10665	COG1012	belongs to the aldehyde dehydrogenase family
NX823_10670	COG1657	PFAM Prenyltransferase squalene oxidase
NX823_10675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NX823_10680	COG0733	neurotransmitter:sodium symporter activity
NX823_10685	COG0385	Bile acid
NX823_10690	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX823_10695	COG0567	Dehydrogenase, E1 component
NX823_10700	COG4548	von Willebrand factor, type A
NX823_10705	COG0714	Associated with various cellular activities
NX823_10710	COG2032	superoxide dismutase activity
NX823_10715	COG1388	LysM domain
NX823_10715	COG0791	NLP P60 protein
NX823_10720	COG1819	glycosyl
NX823_10725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NX823_10730	COG0534	Mate efflux family protein
NX823_10735	COG1366	Belongs to the anti-sigma-factor antagonist family
NX823_10740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NX823_10745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NX823_10755	COG2962	Rard protein
NX823_10770	COG2610	gluconate transmembrane transporter activity
NX823_10775	COG2610	gluconate transmembrane transporter activity
NX823_10780	COG1942	4-Oxalocrotonate Tautomerase
NX823_10785	COG1733	regulation of RNA biosynthetic process
NX823_10790	COG0778	Nitroreductase
NX823_10795	COG0400	carboxylic ester hydrolase activity
NX823_10800	COG0346	lactoylglutathione lyase activity
NX823_10810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX823_10815	COG0793	Belongs to the peptidase S41A family
NX823_10815	COG3409	Peptidoglycan-binding domain 1 protein
NX823_10820	COG2226	methyltransferase
NX823_10830	COG1876	peptidase activity
NX823_10835	COG0813	purine-nucleoside phosphorylase activity
NX823_10850	COG0671	phosphoesterase, PA-phosphatase related
NX823_10870	COG4479	Belongs to the UPF0346 family
NX823_10935	COG0827	DNA restriction-modification system
NX823_10955	COG3328	transposase activity
NX823_10970	COG0456	acetyltransferase
NX823_10975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX823_10980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NX823_10985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NX823_10990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NX823_11005	COG0456	acetyltransferase
NX823_11010	COG0463	Glycosyl transferase, family 2
NX823_11025	COG4641	Protein conserved in bacteria
NX823_11030	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
NX823_11035	COG1086	Polysaccharide biosynthesis protein
NX823_11040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NX823_11045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NX823_11050	COG1846	Transcriptional regulator
NX823_11055	COG0534	Mate efflux family protein
NX823_11065	COG4698	Protein conserved in bacteria
NX823_11070	COG2755	lipolytic protein G-D-S-L family
NX823_11075	COG1999	signal sequence binding
NX823_11085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NX823_11090	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NX823_11095	COG1272	protein, Hemolysin III
NX823_11100	COG0204	Acyl-transferase
NX823_11105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NX823_11110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NX823_11120	COG2521	methyltransferase
NX823_11120	COG2136	Putative SAM-dependent methyltransferase
NX823_11130	COG0129	dihydroxy-acid dehydratase activity
NX823_11135	COG1413	lyase activity
NX823_11140	COG1418	mRNA catabolic process
NX823_11145	COG0386	Belongs to the glutathione peroxidase family
NX823_11150	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NX823_11155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NX823_11165	COG1278	Cold shock
NX823_11185	COG0328	RNA-DNA hybrid ribonuclease activity
NX823_11190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NX823_11195	COG0328	RNA-DNA hybrid ribonuclease activity
NX823_11205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NX823_11220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NX823_11230	COG1755	Isoprenylcysteine carboxyl methyltransferase
NX823_11240	COG2233	PERMEase
NX823_11245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NX823_11250	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NX823_11260	COG0800	Aldolase
NX823_11265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX823_11270	COG1609	Transcriptional regulator
NX823_11275	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NX823_11280	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_11285	COG1199	ATP-dependent helicase activity
NX823_11300	COG0116	Belongs to the methyltransferase superfamily
NX823_11315	COG4474	Belongs to the UPF0398 family
NX823_11330	COG3359	exonuclease
NX823_11335	COG1111	helicase
NX823_11335	COG1205	dead DEAH box helicase
NX823_11340	COG2190	(PTS) system
NX823_11345	COG0071	Belongs to the small heat shock protein (HSP20) family
NX823_11380	COG3331	DNA recombination
NX823_11385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NX823_11385	COG4499	WXG100 protein secretion system (Wss), protein YukC
NX823_11395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NX823_11400	COG3935	DnaD domain protein
NX823_11405	COG0017	Asparaginyl-tRNA synthetase
NX823_11410	COG0436	Aminotransferase
NX823_11415	COG5353	protein conserved in bacteria
NX823_11425	COG1199	ATP-dependent helicase activity
NX823_11425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NX823_11430	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NX823_11435	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NX823_11440	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NX823_11445	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NX823_11445	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NX823_11450	COG0617	tRNA 3'-terminal CCA addition
NX823_11455	COG0438	transferase activity, transferring glycosyl groups
NX823_11460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NX823_11465	COG1803	Methylglyoxal synthase
NX823_11470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NX823_11475	COG1694	Mazg nucleotide pyrophosphohydrolase
NX823_11480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX823_11490	COG4347	Protein of unknown function (DUF1405)
NX823_11495	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NX823_11495	COG2010	Cytochrome c
NX823_11500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NX823_11505	COG0723	plastoquinol--plastocyanin reductase activity
NX823_11515	COG5582	Belongs to the UPF0302 family
NX823_11520	COG0457	Tetratricopeptide repeat
NX823_11525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NX823_11530	COG0287	Prephenate dehydrogenase
NX823_11545	COG0133	tryptophan synthase activity
NX823_11550	COG0135	phosphoribosylanthranilate isomerase activity
NX823_11560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NX823_11565	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NX823_11570	COG4401	Chorismate mutase type I
NX823_11575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NX823_11580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NX823_11585	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NX823_11590	COG0105	UTP biosynthetic process
NX823_11595	COG0142	geranyltranstransferase activity
NX823_11600	COG2226	methyltransferase
NX823_11605	COG0142	geranyltranstransferase activity
NX823_11615	COG0302	gtp cyclohydrolase
NX823_11620	COG0776	regulation of translation
NX823_11625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NX823_11640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NX823_11645	COG1160	GTP binding
NX823_11670	COG1304	FMN binding
NX823_11675	COG0539	negative regulation of cytoplasmic translation
NX823_11680	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NX823_11690	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NX823_11695	COG2959	enzyme of heme biosynthesis
NX823_11700	COG3773	Cell wall hydrolase
NX823_11700	COG3409	Peptidoglycan-binding domain 1 protein
NX823_11705	COG2339	peptidase activity
NX823_11710	COG0492	ferredoxin-NADP+ reductase activity
NX823_11715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NX823_11720	COG4862	establishment of competence for transformation
NX823_11725	COG1408	metallophosphoesterase
NX823_11735	COG1388	LysM domain
NX823_11740	COG1266	CAAX protease self-immunity
NX823_11745	COG0514	ATP-dependent DNA helicase (RecQ)
NX823_11750	COG4955	Helix-turn-helix domain
NX823_11755	COG1141	Ferredoxin
NX823_11760	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NX823_11765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NX823_11770	COG0710	3-dehydroquinate dehydratase activity
NX823_11780	COG1595	DNA-templated transcription, initiation
NX823_11785	COG5002	protein histidine kinase activity
NX823_11790	COG0745	RESPONSE REGULATOR receiver
NX823_11795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NX823_11800	COG1333	cytochrome c biogenesis protein
NX823_11805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX823_11810	COG1187	pseudouridine synthase activity
NX823_11815	COG0700	Nucleoside recognition
NX823_11820	COG2715	membrane protein required for spore maturation
NX823_11825	COG1686	Belongs to the peptidase S11 family
NX823_11835	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NX823_11840	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NX823_11845	COG1547	Domain of unknown function (DUF309)
NX823_11850	COG0456	acetyltransferase
NX823_11855	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NX823_11860	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NX823_11860	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NX823_11865	COG0307	riboflavin synthase, alpha
NX823_11870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NX823_11870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NX823_11880	COG0681	Belongs to the peptidase S26 family
NX823_11890	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NX823_11935	COG3012	SEC-C Motif Domain Protein
NX823_11950	COG0457	Tetratricopeptide repeat
NX823_11960	COG3328	transposase activity
NX823_12010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NX823_12020	COG4086	secreted protein
NX823_12025	COG0019	diaminopimelate decarboxylase activity
NX823_12030	COG0697	spore germination
NX823_12045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX823_12065	COG1191	sigma factor activity
NX823_12070	COG2172	sigma factor antagonist activity
NX823_12075	COG1366	Belongs to the anti-sigma-factor antagonist family
NX823_12080	COG1686	Belongs to the peptidase S11 family
NX823_12085	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NX823_12090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NX823_12095	COG4974	Belongs to the 'phage' integrase family
NX823_12105	COG0735	belongs to the Fur family
NX823_12110	COG1300	Membrane
NX823_12120	COG0281	malic enzyme
NX823_12125	COG1757	Na H antiporter
NX823_12130	COG1027	Aspartate ammonia-lyase
NX823_12135	COG0252	asparaginase activity
NX823_12140	COG1396	sequence-specific DNA binding
NX823_12145	COG1379	DNA repair
NX823_12150	COG0494	nUDIX hydrolase
NX823_12160	COG0667	Aldo Keto reductase
NX823_12170	COG1073	alpha beta
NX823_12180	COG4918	Iron-sulphur cluster biosynthesis
NX823_12185	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NX823_12185	COG0456	acetyltransferase
NX823_12190	COG2329	Antibiotic biosynthesis monooxygenase
NX823_12195	COG0456	acetyltransferase
NX823_12205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NX823_12215	COG2211	Major facilitator Superfamily
NX823_12225	COG0346	lactoylglutathione lyase activity
NX823_12230	COG1072	(Pantothenic acid kinase))
NX823_12235	COG3048	D-serine ammonia-lyase activity
NX823_12240	COG0300	oxidoreductase activity
NX823_12245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX823_12250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NX823_12255	COG4187	Peptidase family M20/M25/M40
NX823_12260	COG1902	pentaerythritol trinitrate reductase activity
NX823_12265	COG0596	Alpha beta hydrolase
NX823_12275	COG1234	tRNA 3'-trailer cleavage
NX823_12280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NX823_12285	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NX823_12290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NX823_12300	COG0706	membrane insertase activity
NX823_12305	COG3361	conserved protein (COG2071)
NX823_12315	COG2195	Cleaves the N-terminal amino acid of tripeptides
NX823_12320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NX823_12325	COG0346	lactoylglutathione lyase activity
NX823_12335	COG1376	ErfK ybiS ycfS ynhG family protein
NX823_12340	COG4129	membrane
NX823_12345	COG1126	abc transporter atp-binding protein
NX823_12350	COG0765	amino acid transport
NX823_12355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX823_12365	COG1597	lipid kinase activity
NX823_12375	COG4978	Transcriptional regulator
NX823_12375	COG0789	Transcriptional regulator
NX823_12380	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX823_12385	COG0022	dehydrogenase e1 component
NX823_12390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NX823_12395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NX823_12400	COG3426	butyrate kinase activity
NX823_12405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NX823_12410	COG0280	phosphate acetyltransferase
NX823_12415	COG3290	protein histidine kinase activity
NX823_12415	COG3829	transcription factor binding
NX823_12425	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NX823_12430	COG2079	MmgE PrpD family protein
NX823_12435	COG0372	Belongs to the citrate synthase family
NX823_12445	COG1250	3-hydroxyacyl-CoA dehydrogenase
NX823_12450	COG0183	Belongs to the thiolase family
NX823_12455	COG0584	glycerophosphoryl diester phosphodiesterase
NX823_12460	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX823_12480	COG0745	RESPONSE REGULATOR receiver
NX823_12485	COG0750	zinc metalloprotease
NX823_12490	COG0497	DNA recombination
NX823_12495	COG1438	arginine binding
NX823_12500	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NX823_12505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NX823_12510	COG0142	geranyltranstransferase activity
NX823_12515	COG1722	exodeoxyribonuclease VII activity
NX823_12520	COG1570	exodeoxyribonuclease VII activity
NX823_12525	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NX823_12530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NX823_12535	COG1302	Protein conserved in bacteria
NX823_12540	COG0439	Biotin carboxylase
NX823_12545	COG0511	ligase activity, forming carbon-carbon bonds
NX823_12585	COG3854	ATPases associated with a variety of cellular activities
NX823_12595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NX823_12600	COG0006	proline dipeptidase activity
NX823_12605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NX823_12615	COG3872	metal-dependent enzyme
NX823_12625	COG1752	Esterase of the alpha-beta hydrolase superfamily
NX823_12630	COG1321	iron dependent repressor
NX823_12635	COG0095	Lipoate-protein ligase
NX823_12640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NX823_12650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NX823_12655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NX823_12660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NX823_12665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NX823_12680	COG1396	sequence-specific DNA binding
NX823_12690	COG0681	Belongs to the peptidase S26 family
NX823_12715	COG4940	Competence protein ComGF
NX823_12725	COG4970	Tfp pilus assembly protein FimT
NX823_12730	COG4537	Required for transformation and DNA binding
NX823_12735	COG1459	type II secretion system
NX823_12740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NX823_12745	COG0517	IMP dehydrogenase activity
NX823_12750	COG0598	Magnesium transport protein CorA
NX823_12755	COG1253	flavin adenine dinucleotide binding
NX823_12760	COG1366	Belongs to the anti-sigma-factor antagonist family
NX823_12770	COG1393	Belongs to the ArsC family
NX823_12780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX823_12790	COG0011	TIGRFAM Protein of
NX823_12800	COG2866	Carboxypeptidase
NX823_12805	COG1368	sulfuric ester hydrolase activity
NX823_12810	COG1940	carbohydrate kinase activity
NX823_12815	COG4483	Protein conserved in bacteria
NX823_12820	COG0705	Rhomboid family
NX823_12820	COG0457	Tetratricopeptide repeat
NX823_12830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NX823_12840	COG0438	transferase activity, transferring glycosyl groups
NX823_12855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NX823_12860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NX823_12865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NX823_12870	COG0581	inorganic phosphate transmembrane transporter activity
NX823_12875	COG0573	inorganic phosphate transmembrane transporter activity
NX823_12880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NX823_12885	COG0768	penicillin binding
NX823_12890	COG0477	Major facilitator Superfamily
NX823_12895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NX823_12900	COG2839	Protein conserved in bacteria
NX823_12905	COG5521	maltodextrose utilization protein MalA
NX823_12910	COG1388	LysM domain
NX823_12915	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NX823_12920	COG4709	membrane
NX823_12925	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NX823_12930	COG0735	belongs to the Fur family
NX823_12935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX823_12945	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NX823_12950	COG0513	Belongs to the DEAD box helicase family
NX823_12960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NX823_12965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NX823_12970	COG2384	SAM-dependent methyltransferase
NX823_12975	COG2010	Cytochrome c
NX823_12980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NX823_12985	COG0358	DNA primase activity
NX823_12990	COG1671	Belongs to the UPF0178 family
NX823_12995	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NX823_13000	COG0517	IMP dehydrogenase activity
NX823_13005	COG0751	glycine-tRNA ligase activity
NX823_13010	COG0752	glycyl-tRNA synthetase alpha subunit
NX823_13015	COG1381	Involved in DNA repair and RecF pathway recombination
NX823_13025	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NX823_13030	COG0295	cytidine deaminase activity
NX823_13035	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NX823_13040	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NX823_13045	COG1480	7TM receptor with intracellular HD hydrolase
NX823_13050	COG1702	phosphate starvation-inducible protein PhoH
NX823_13055	COG0561	phosphatase activity
NX823_13070	COG4864	UPF0365 protein
NX823_13075	COG1030	water channel activity
NX823_13080	COG1610	YqeY-like protein
NX823_13090	COG1283	sodium-dependent phosphate transmembrane transporter activity
NX823_13095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NX823_13100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NX823_13105	COG2264	protein methyltransferase activity
NX823_13110	COG0484	heat shock protein binding
NX823_13115	COG0443	Heat shock 70 kDa protein
NX823_13120	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NX823_13125	COG1420	regulation of RNA biosynthetic process
NX823_13130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NX823_13135	COG0481	GTPase activity
NX823_13145	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX823_13150	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NX823_13155	COG0268	Binds directly to 16S ribosomal RNA
NX823_13160	COG1466	dna polymerase III delta subunit
NX823_13175	COG0658	competence protein
NX823_13175	COG2333	competence protein COMEC
NX823_13180	COG2131	deaminase
NX823_13185	COG1555	photosystem II stabilization
NX823_13185	COG1596	polysaccharide export
NX823_13190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NX823_13195	COG2226	methyltransferase
NX823_13200	COG0799	negative regulation of ribosome biogenesis
NX823_13205	COG1713	HD superfamily hydrolase involved in NAD metabolism
NX823_13210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NX823_13215	COG1534	Rna-binding protein
NX823_13220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NX823_13225	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NX823_13230	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NX823_13240	COG2755	lipolytic protein G-D-S-L family
NX823_13245	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX823_13245	COG3409	Peptidoglycan-binding domain 1 protein
NX823_13250	COG0398	Pfam SNARE associated Golgi protein
NX823_13255	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NX823_13270	COG3209	COG3209 Rhs family protein
NX823_13290	COG0114	fumarate hydratase activity
NX823_13295	COG0583	DNA-binding transcription factor activity
NX823_13310	COG0457	Tetratricopeptide repeat
NX823_13440	COG4978	Transcriptional regulator
NX823_13440	COG0789	Transcriptional regulator
NX823_13445	COG2814	Major facilitator Superfamily
NX823_13450	COG0456	acetyltransferase
NX823_13455	COG3328	transposase activity
NX823_13460	COG1253	flavin adenine dinucleotide binding
NX823_13470	COG0697	spore germination
NX823_13475	COG0583	DNA-binding transcription factor activity
NX823_13480	COG2072	flavoprotein involved in K transport
NX823_13485	COG1230	cation diffusion facilitator family transporter
NX823_13500	COG1114	Component of the transport system for branched-chain amino acids
NX823_13505	COG1687	branched-chain amino acid
NX823_13510	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NX823_13515	COG1522	sequence-specific DNA binding
NX823_13520	COG2732	(Barnase) inhibitor
NX823_13525	COG2124	cytochrome p450
NX823_13535	COG1335	isochorismatase
NX823_13555	COG2318	DinB family
NX823_13565	COG2070	2-Nitropropane dioxygenase
NX823_13570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NX823_13600	COG0789	Transcriptional regulator
NX823_13600	COG4978	Transcriptional regulator
NX823_13605	COG2315	Protein conserved in bacteria
NX823_13620	COG3443	Belongs to the bacterial solute-binding protein 9 family
NX823_13625	COG1595	DNA-templated transcription, initiation
NX823_13630	COG0667	Aldo Keto reductase
NX823_13635	COG3409	Peptidoglycan-binding domain 1 protein
NX823_13640	COG5566	PFAM Mor transcription activator
NX823_13645	COG0596	Alpha beta hydrolase
NX823_13650	COG4991	sh3 domain protein
NX823_13655	COG4991	sh3 domain protein
NX823_13665	COG0346	lactoylglutathione lyase activity
NX823_13675	COG5577	PFAM Coat F domain
NX823_13680	COG1063	alcohol dehydrogenase
NX823_13690	COG5577	PFAM Coat F domain
NX823_13695	COG0789	Transcriptional regulator
NX823_13705	COG1064	alcohol dehydrogenase
NX823_13710	COG0693	protein deglycase activity
NX823_13715	COG1621	beta-fructofuranosidase activity
NX823_13720	COG3716	PTS system mannose fructose sorbose family IID component
NX823_13725	COG3715	PTS system
NX823_13730	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX823_13735	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX823_13740	COG3933	PFAM sigma-54 factor interaction domain-containing protein
NX823_13740	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NX823_13750	COG1113	amino acid transport
NX823_13755	COG1280	lysine exporter protein (LysE YggA)
NX823_13760	COG1378	Sugar-specific transcriptional regulator TrmB
NX823_13765	COG1595	DNA-templated transcription, initiation
NX823_13775	COG2755	lipolytic protein G-D-S-L family
NX823_13775	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NX823_13785	COG2124	cytochrome p450
NX823_13785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX823_13790	COG1309	transcriptional regulator
NX823_13820	COG2116	formate transmembrane transporter activity
NX823_13825	COG5609	conserved protein (DUF2294)
NX823_13830	COG3383	formate dehydrogenase (NAD+) activity
NX823_13835	COG2427	Protein of unknown function (DUF1641)
NX823_13845	COG0626	cystathionine gamma-synthase activity
NX823_13850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NX823_13855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NX823_13860	COG2226	methyltransferase
NX823_13875	COG0768	penicillin binding
NX823_13880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NX823_13885	COG0572	uridine kinase
NX823_13890	COG0826	peptidase U32
NX823_13895	COG0826	peptidase U32
NX823_13900	COG4122	O-methyltransferase activity
NX823_13905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NX823_13910	COG3906	Belongs to the UPF0473 family
NX823_13915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NX823_13920	COG4472	Bacterial protein of unknown function (DUF965)
NX823_13925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NX823_13930	COG0628	permease
NX823_13935	COG1126	abc transporter atp-binding protein
NX823_13940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX823_13945	COG0765	amino acid transport
NX823_13950	COG0765	amino acid transport
NX823_13965	COG3881	PFAM PRC-barrel domain
NX823_13970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NX823_13975	COG0457	Tetratricopeptide repeat
NX823_13980	COG0482	sulfurtransferase activity
NX823_13985	COG1104	cysteine desulfurase activity
NX823_13990	COG1959	2 iron, 2 sulfur cluster binding
NX823_13995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NX823_14000	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NX823_14010	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NX823_14015	COG0124	histidyl-tRNA synthetase
NX823_14025	COG4991	sh3 domain protein
NX823_14025	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX823_14025	COG3103	Sh3 type 3 domain protein
NX823_14030	COG1490	D-aminoacyl-tRNA deacylase activity
NX823_14035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NX823_14040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NX823_14045	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NX823_14045	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NX823_14050	COG5416	Lipopolysaccharide assembly protein A domain
NX823_14055	COG0490	domain, Protein
NX823_14060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NX823_14060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NX823_14070	COG2244	polysaccharide biosynthetic process
NX823_14075	COG2323	membrane
NX823_14085	COG1862	Preprotein translocase
NX823_14090	COG0343	queuine tRNA-ribosyltransferase activity
NX823_14095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NX823_14105	COG2255	four-way junction helicase activity
NX823_14110	COG0632	four-way junction helicase activity
NX823_14120	COG2814	Major facilitator Superfamily
NX823_14125	COG0673	inositol 2-dehydrogenase activity
NX823_14155	COG1115	amino acid carrier protein
NX823_14160	COG0217	transcriptional regulatory protein
NX823_14170	COG1388	LysM domain
NX823_14175	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NX823_14180	COG0157	Belongs to the NadC ModD family
NX823_14185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NX823_14190	COG1104	cysteine desulfurase activity
NX823_14195	COG1827	regulation of RNA biosynthetic process
NX823_14200	COG0077	Prephenate dehydratase
NX823_14205	COG4492	Belongs to the UPF0735 family
NX823_14210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NX823_14215	COG3290	protein histidine kinase activity
NX823_14225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NX823_14230	COG2868	ribosomal protein
NX823_14235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NX823_14240	COG1994	Peptidase M50
NX823_14245	COG0739	heme binding
NX823_14250	COG2894	cell division
NX823_14255	COG0850	regulation of cytokinetic process
NX823_14260	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NX823_14270	COG1077	Cell shape determining protein MreB Mrl
NX823_14275	COG2003	Belongs to the UPF0758 family
NX823_14280	COG0424	maF-like protein
NX823_14290	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NX823_14295	COG0285	dihydrofolate synthase activity
NX823_14300	COG0525	valine-tRNA ligase activity
NX823_14310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NX823_14315	COG1388	LysM domain
NX823_14320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NX823_14325	COG0113	porphobilinogen synthase activity
NX823_14330	COG1587	Uroporphyrinogen-III synthase
NX823_14335	COG0181	hydroxymethylbilane synthase activity
NX823_14340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NX823_14345	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NX823_14355	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NX823_14360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NX823_14365	COG0470	DNA polymerase III
NX823_14365	COG1067	ATP-dependent peptidase activity
NX823_14370	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NX823_14375	COG0544	peptidyl-prolyl cis-trans isomerase activity
NX823_14380	COG1477	protein flavinylation
NX823_14380	COG0457	Tetratricopeptide repeat
NX823_14385	COG0066	3-isopropylmalate dehydratase activity
NX823_14390	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NX823_14395	COG0473	3-isopropylmalate dehydrogenase activity
NX823_14400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NX823_14405	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NX823_14410	COG0440	acetolactate synthase activity
NX823_14415	COG0028	Belongs to the TPP enzyme family
NX823_14430	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NX823_14440	COG0622	Phosphoesterase
NX823_14445	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NX823_14450	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NX823_14455	COG5401	PFAM Sporulation and spore germination
NX823_14460	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NX823_14465	COG1846	Transcriptional regulator
NX823_14475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX823_14495	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX823_14495	COG3409	Peptidoglycan-binding domain 1 protein
NX823_14495	COG1388	LysM domain
NX823_14560	COG1388	LysM domain
NX823_14560	COG0791	NLP P60 protein
NX823_14565	COG3953	SLT domain
NX823_14565	COG5280	Phage tail tape measure protein TP901
NX823_14635	COG5484	DNA packaging
NX823_14665	COG1595	DNA-templated transcription, initiation
NX823_14715	COG1484	DNA-dependent DNA replication
NX823_14720	COG3935	DnaD domain protein
NX823_14725	COG3723	Recombinational DNA repair protein, rece pathway
NX823_14730	COG5377	YqaJ viral recombinase family
NX823_14770	COG3620	sequence-specific DNA binding
NX823_14775	COG1525	nuclease
NX823_14785	COG2856	Zn peptidase
NX823_14790	COG2197	response regulator
NX823_14795	COG0824	Thioesterase
NX823_14800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NX823_14805	COG1053	succinate dehydrogenase
NX823_14810	COG2009	succinate dehydrogenase
NX823_14815	COG1719	4-vinyl reductase, 4VR
NX823_14820	COG0527	aspartate kinase activity
NX823_14825	COG0322	excinuclease ABC activity
NX823_14830	COG3118	belongs to the thioredoxin family
NX823_14835	COG3534	alpha-L-arabinofuranosidase
NX823_14840	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NX823_14845	COG2086	electron transfer activity
NX823_14850	COG1024	Enoyl-CoA hydratase
NX823_14855	COG1309	transcriptional regulator
NX823_14860	COG0318	PFAM AMP-dependent synthetase and ligase
NX823_14865	COG3766	membrane
NX823_14870	COG1193	negative regulation of DNA recombination
NX823_14875	COG1796	DNA polymerase
NX823_14875	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NX823_14880	COG1286	toxin biosynthetic process
NX823_14885	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NX823_14890	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NX823_14895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX823_14895	COG0072	phenylalanine-tRNA ligase activity
NX823_14900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NX823_14910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NX823_14925	COG0277	FAD linked oxidase domain protein
NX823_14930	COG0247	lactate metabolic process
NX823_14935	COG0346	lactoylglutathione lyase activity
NX823_14945	COG1966	Carbon starvation protein
NX823_14950	COG3534	alpha-L-arabinofuranosidase
NX823_14955	COG0395	ABC-type sugar transport system, permease component
NX823_14960	COG1175	transmembrane transport
NX823_14965	COG1653	transport
NX823_14970	COG0371	Dehydrogenase
NX823_14975	COG0647	UMP catabolic process
NX823_14980	COG0235	Class ii aldolase
NX823_14985	COG1069	ribulokinase activity
NX823_14990	COG2160	L-arabinose isomerase activity
NX823_15000	COG3507	Belongs to the glycosyl hydrolase 43 family
NX823_15005	COG1363	Peptidase, m42
NX823_15015	COG3326	Membrane
NX823_15020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NX823_15025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NX823_15030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NX823_15040	COG1346	cytolysis
NX823_15045	COG1380	Effector of murein hydrolase LrgA
NX823_15050	COG3279	Response regulator of the LytR AlgR family
NX823_15055	COG3275	phosphorelay sensor kinase activity
NX823_15060	COG1011	Hydrolase
NX823_15065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NX823_15075	COG0398	Pfam SNARE associated Golgi protein
NX823_15080	COG1484	DNA-dependent DNA replication
NX823_15085	COG3611	Membrane attachment protein
NX823_15090	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NX823_15095	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NX823_15100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NX823_15105	COG1733	regulation of RNA biosynthetic process
NX823_15110	COG2814	Major facilitator Superfamily
NX823_15115	COG0656	L-ascorbic acid biosynthetic process
NX823_15120	COG0237	dephospho-CoA kinase activity
NX823_15125	COG1971	Probably functions as a manganese efflux pump
NX823_15130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NX823_15135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NX823_15135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NX823_15140	COG5002	protein histidine kinase activity
NX823_15145	COG0745	RESPONSE REGULATOR receiver
NX823_15150	COG0039	L-malate dehydrogenase activity
NX823_15155	COG0538	isocitrate dehydrogenase activity
NX823_15160	COG0372	Belongs to the citrate synthase family
NX823_15175	COG2707	UPF0756 membrane protein
NX823_15180	COG0628	permease
NX823_15185	COG3030	protein affecting phage T7 exclusion by the F plasmid
NX823_15190	COG0469	pyruvate kinase activity
NX823_15195	COG0205	6-phosphofructokinase activity
NX823_15200	COG0825	malonyl-CoA metabolic process
NX823_15205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NX823_15210	COG0281	malic enzyme
NX823_15215	COG0587	DNA-directed DNA polymerase activity
NX823_15235	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NX823_15245	COG4109	DRTGG domain
NX823_15250	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NX823_15255	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_15265	COG0165	Argininosuccinate lyase
NX823_15270	COG0137	argininosuccinate synthase activity
NX823_15275	COG0521	Mo-molybdopterin cofactor biosynthetic process
NX823_15280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NX823_15290	COG0827	DNA restriction-modification system
NX823_15295	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NX823_15300	COG3874	Sporulation protein YtfJ
NX823_15310	COG1714	RDD family
NX823_15315	COG0616	signal peptide processing
NX823_15320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NX823_15325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NX823_15330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NX823_15340	COG0301	tRNA thio-modification
NX823_15345	COG1104	cysteine desulfurase activity
NX823_15350	COG1114	Component of the transport system for branched-chain amino acids
NX823_15355	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NX823_15360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NX823_15365	COG1309	transcriptional regulator
NX823_15370	COG1956	GAF domain-containing protein
NX823_15375	COG2203	Gaf domain
NX823_15375	COG2199	diguanylate cyclase activity
NX823_15380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NX823_15390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NX823_15395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NX823_15400	COG0454	-acetyltransferase
NX823_15405	COG0517	IMP dehydrogenase activity
NX823_15410	COG0123	including yeast histone deacetylase and acetoin utilization protein
NX823_15415	COG1360	Flagellar Motor Protein
NX823_15420	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NX823_15425	COG1609	Transcriptional regulator
NX823_15430	COG1605	Chorismate mutase
NX823_15430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NX823_15435	COG3118	belongs to the thioredoxin family
NX823_15440	COG4980	gas vesicle protein
NX823_15445	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NX823_15450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NX823_15455	COG1674	ftsk spoiiie
NX823_15460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX823_15465	COG4848	Belongs to the UPF0354 family
NX823_15470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX823_15485	COG1363	Peptidase, m42
NX823_15490	COG5584	Small secreted protein
NX823_15495	COG0281	malic enzyme
NX823_15500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX823_15505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NX823_15515	COG0510	thiamine kinase activity
NX823_15520	COG1523	belongs to the glycosyl hydrolase 13 family
NX823_15525	COG1597	lipid kinase activity
NX823_15535	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NX823_15540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NX823_15545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX823_15550	COG2252	PERMEase
NX823_15555	COG4473	ABC transporter
NX823_15560	COG1131	(ABC) transporter
NX823_15565	COG1349	DNA-binding transcription factor activity
NX823_15570	COG1187	pseudouridine synthase activity
NX823_15575	COG2244	polysaccharide biosynthetic process
NX823_15580	COG2081	HI0933 family
NX823_15585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NX823_15595	COG5578	integral membrane protein
NX823_15600	COG0673	inositol 2-dehydrogenase activity
NX823_15605	COG1653	transport
NX823_15610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NX823_15615	COG4209	transmembrane transport
NX823_15625	COG1653	transport
NX823_15630	COG0395	ABC-type sugar transport system, permease component
NX823_15635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX823_15640	COG2124	cytochrome p450
NX823_15645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NX823_15660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NX823_15675	COG1073	alpha beta
NX823_15680	COG1609	Transcriptional regulator
NX823_15685	COG1653	transport
NX823_15690	COG1175	transmembrane transport
NX823_15695	COG0395	ABC-type sugar transport system, permease component
NX823_15700	COG1486	melibiose metabolic process
NX823_15705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NX823_15710	COG0495	leucyl-tRNA aminoacylation
NX823_15720	COG2202	Pas domain
NX823_15720	COG1366	Belongs to the anti-sigma-factor antagonist family
NX823_15725	COG2814	Major facilitator Superfamily
NX823_15730	COG2433	Pfam Transposase IS66
NX823_15735	COG0577	efflux transmembrane transporter activity
NX823_15740	COG1136	(ABC) transporter
NX823_15745	COG2205	protein histidine kinase activity
NX823_15750	COG0745	RESPONSE REGULATOR receiver
NX823_15755	COG0577	efflux transmembrane transporter activity
NX823_15760	COG1136	(ABC) transporter
NX823_15775	COG1131	(ABC) transporter
NX823_15780	COG1725	Transcriptional regulator
NX823_15800	COG1242	4 iron, 4 sulfur cluster binding
NX823_15805	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NX823_15815	COG2267	carboxylic ester hydrolase activity
NX823_15820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NX823_15825	COG1113	amino acid transport
NX823_15830	COG0367	asparagine synthase
NX823_15835	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NX823_15840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NX823_15850	COG1506	peptidase
NX823_15855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NX823_15860	COG1116	anion transmembrane transporter activity
NX823_15865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NX823_15870	COG0494	nUDIX hydrolase
NX823_15875	COG4824	toxin secretion phage lysis holin
NX823_15880	COG0783	Belongs to the Dps family
NX823_15895	COG1854	S-ribosylhomocysteine lyase activity
NX823_15900	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NX823_15905	COG0288	reversible hydration of carbon dioxide
NX823_15910	COG0254	rRNA binding
NX823_15915	COG1271	oxidase subunit
NX823_15920	COG1294	oxidase, subunit
NX823_15935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NX823_15940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NX823_15940	COG1321	iron dependent repressor
NX823_15945	COG1121	(ABC) transporter
NX823_15950	COG0803	Belongs to the bacterial solute-binding protein 9 family
NX823_15955	COG4948	Mandelate Racemase Muconate Lactonizing
NX823_15960	COG0318	PFAM AMP-dependent synthetase and ligase
NX823_15965	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NX823_15970	COG0596	Alpha beta hydrolase
NX823_15975	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NX823_15980	COG1169	isochorismate synthase
NX823_15985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX823_15990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NX823_15995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NX823_16000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX823_16005	COG0438	transferase activity, transferring glycosyl groups
NX823_16015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NX823_16020	COG0438	transferase activity, transferring glycosyl groups
NX823_16025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NX823_16030	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NX823_16035	COG0058	SHG alpha-glucan phosphorylase activity
NX823_16040	COG0297	glycogen (starch) synthase activity
NX823_16045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NX823_16050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NX823_16055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NX823_16180	COG3859	Proton-coupled thiamine transporter YuaJ
NX823_16185	COG1247	-acetyltransferase
NX823_16190	COG2268	Band 7 protein
NX823_16195	COG1585	Membrane protein implicated in regulation of membrane protease activity
NX823_16200	COG2318	DinB family
NX823_16210	COG1454	alcohol dehydrogenase
NX823_16215	COG1012	belongs to the aldehyde dehydrogenase family
NX823_16220	COG1510	regulation of RNA biosynthetic process
NX823_16230	COG0569	domain protein
NX823_16235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NX823_16240	COG4682	membrane
NX823_16245	COG1705	Flagellar rod assembly protein muramidase FlgJ
NX823_16250	COG0477	Major facilitator Superfamily
NX823_16255	COG5553	Cysteine dioxygenase type I
NX823_16265	COG1968	undecaprenyl-diphosphatase activity
NX823_16270	COG0628	permease
NX823_16275	COG0673	inositol 2-dehydrogenase activity
NX823_16280	COG4806	L-rhamnose isomerase
NX823_16285	COG3254	rhamnose metabolic process
NX823_16290	COG1070	Carbohydrate kinase
NX823_16295	COG1349	DNA-binding transcription factor activity
NX823_16300	COG3347	Dehydrogenase
NX823_16300	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_16305	COG0840	transmembrane signaling receptor activity
NX823_16310	COG0840	transmembrane signaling receptor activity
NX823_16315	COG0840	transmembrane signaling receptor activity
NX823_16320	COG0840	transmembrane signaling receptor activity
NX823_16335	COG0432	Pfam Uncharacterised protein family UPF0047
NX823_16345	COG0366	Alpha amylase catalytic
NX823_16350	COG1253	flavin adenine dinucleotide binding
NX823_16355	COG2738	Putative neutral zinc metallopeptidase
NX823_16370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NX823_16385	COG0166	Belongs to the GPI family
NX823_16390	COG1979	alcohol dehydrogenase
NX823_16395	COG1979	alcohol dehydrogenase
NX823_16400	COG2155	Conserved Protein
NX823_16405	COG1098	S1 RNA binding domain
NX823_16410	COG0436	Aminotransferase
NX823_16415	COG1522	sequence-specific DNA binding
NX823_16420	COG2267	carboxylic ester hydrolase activity
NX823_16430	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NX823_16435	COG2205	protein histidine kinase activity
NX823_16445	COG5018	Exonuclease
NX823_16455	COG2814	Major facilitator Superfamily
NX823_16460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NX823_16465	COG3011	Protein conserved in bacteria
NX823_16475	COG3290	protein histidine kinase activity
NX823_16480	COG4565	transcriptional regulatory protein
NX823_16485	COG1744	ABC transporter substrate-binding protein PnrA-like
NX823_16490	COG3845	ABC transporter
NX823_16500	COG1079	Belongs to the binding-protein-dependent transport system permease family
NX823_16505	COG3493	citrate carrier protein
NX823_16515	COG2111	Na H antiporter
NX823_16515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NX823_16520	COG2111	Na H antiporter
NX823_16525	COG1006	Multisubunit Na H antiporter MnhC subunit
NX823_16530	COG0651	ATP synthesis coupled electron transport
NX823_16535	COG1863	multisubunit Na H antiporter MnhE subunit
NX823_16540	COG2212	antiporter activity
NX823_16545	COG1320	monovalent cation:proton antiporter activity
NX823_16550	COG2050	protein possibly involved in aromatic compounds catabolism
NX823_16555	COG2197	response regulator
NX823_16560	COG4585	Histidine kinase
NX823_16570	COG0142	geranyltranstransferase activity
NX823_16595	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NX823_16600	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NX823_16605	COG1335	isochorismatase
NX823_16610	COG5506	Protein of unknown function (DUF1694)
NX823_16625	COG0628	permease
NX823_16640	COG1418	mRNA catabolic process
NX823_16645	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_16655	COG1511	domain protein
NX823_16660	COG1674	ftsk spoiiie
NX823_16660	COG0433	COG0433 Predicted ATPase
NX823_16665	COG4499	WXG100 protein secretion system (Wss), protein YukC
NX823_16670	COG5417	Belongs to the EsaB family
NX823_16675	COG4842	Belongs to the WXG100 family
NX823_16680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NX823_16680	COG2508	Transcriptional regulator
NX823_16685	COG0686	Belongs to the AlaDH PNT family
NX823_16690	COG5634	Uncharacterized conserved protein (DUF2278)
NX823_16695	COG3251	PFAM MbtH domain protein
NX823_16700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX823_16705	COG3433	isochorismatase activity
NX823_16705	COG1535	isochorismatase
NX823_16710	COG1021	2,3-dihydroxybenzoate-AMP ligase
NX823_16715	COG1169	isochorismate synthase
NX823_16720	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_16725	COG2819	hydrolase of the alpha beta superfamily
NX823_16730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NX823_16735	COG1268	BioY protein
NX823_16740	COG2056	Na+-H+ antiporter family
NX823_16745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NX823_16750	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NX823_16760	COG3584	3D domain protein
NX823_16775	COG1252	NADH dehydrogenase
NX823_16780	COG0492	ferredoxin-NADP+ reductase activity
NX823_16790	COG0516	GMP reductase activity
NX823_16805	COG0316	Belongs to the HesB IscA family
NX823_16810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NX823_16815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NX823_16820	COG4844	belongs to the
NX823_16825	COG1252	NADH dehydrogenase
NX823_16830	COG4837	Protein of unknown function (DUF1462)
NX823_16835	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NX823_16840	COG4946	Tricorn protease homolog
NX823_16840	COG1506	peptidase
NX823_16840	COG0823	Involved in the tonB-independent uptake of proteins
NX823_16845	COG0083	homoserine kinase activity
NX823_16850	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NX823_16855	COG0460	homoserine dehydrogenase
NX823_16860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NX823_16865	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NX823_16870	COG0647	UMP catabolic process
NX823_16875	COG2445	Protein of unknown function DUF86
NX823_16880	COG4470	Protein conserved in bacteria
NX823_16890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NX823_16895	COG0739	heme binding
NX823_16905	COG3377	Domain of unknown function (DUF1805)
NX823_16910	COG0737	Belongs to the 5'-nucleotidase family
NX823_16915	COG0730	response to heat
NX823_16920	COG1801	Protein of unknown function DUF72
NX823_16930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NX823_16935	COG2508	Transcriptional regulator
NX823_16940	COG2233	PERMEase
NX823_16950	COG3195	allantoin biosynthetic process
NX823_16950	COG3648	Uricase
NX823_16955	COG2351	hydroxyisourate hydrolase activity
NX823_16965	COG2080	2 iron, 2 sulfur cluster binding
NX823_16970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NX823_16975	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NX823_16980	COG2068	MobA-Related Protein
NX823_16985	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NX823_16990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NX823_16995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX823_17005	COG2356	endonuclease I
NX823_17010	COG3842	ATPase activity
NX823_17015	COG2188	Transcriptional regulator
NX823_17020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX823_17025	COG0395	ABC-type sugar transport system, permease component
NX823_17030	COG1175	transmembrane transport
NX823_17035	COG1653	transport
NX823_17040	COG2222	sugar isomerase
NX823_17045	COG0322	excinuclease ABC activity
NX823_17050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX823_17065	COG0346	lactoylglutathione lyase activity
NX823_17070	COG0640	Transcriptional regulator
NX823_17075	COG0719	Fe-S assembly protein
NX823_17080	COG0822	iron-sulfur transferase activity
NX823_17085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NX823_17090	COG0719	Fe-S assembly protein
NX823_17095	COG0396	ATPase activity
NX823_17105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NX823_17110	COG1464	Belongs to the NlpA lipoprotein family
NX823_17115	COG2011	ABC-type metal ion transport system permease component
NX823_17120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NX823_17130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX823_17135	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NX823_17145	COG0509	glycine decarboxylation via glycine cleavage system
NX823_17150	COG1393	Belongs to the ArsC family
NX823_17155	COG1960	acyl-CoA dehydrogenase activity
NX823_17160	COG0183	Belongs to the thiolase family
NX823_17165	COG1250	3-hydroxyacyl-CoA dehydrogenase
NX823_17165	COG1024	Enoyl-CoA hydratase
NX823_17185	COG5577	PFAM Coat F domain
NX823_17190	COG1846	Transcriptional regulator
NX823_17195	COG0477	Major facilitator Superfamily
NX823_17200	COG1942	4-Oxalocrotonate Tautomerase
NX823_17205	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_17210	COG0583	DNA-binding transcription factor activity
NX823_17220	COG1120	ATPase activity
NX823_17240	COG1131	(ABC) transporter
NX823_17285	COG0783	Belongs to the Dps family
NX823_17290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX823_17295	COG0745	RESPONSE REGULATOR receiver
NX823_17300	COG2770	Histidine kinase
NX823_17300	COG2205	protein histidine kinase activity
NX823_17310	COG1309	transcriptional regulator
NX823_17315	COG0114	fumarate hydratase activity
NX823_17325	COG0697	spore germination
NX823_17330	COG0814	amino acid
NX823_17340	COG2197	response regulator
NX823_17345	COG4585	Histidine kinase
NX823_17350	COG4758	membrane
NX823_17355	COG3595	metallopeptidase activity
NX823_17360	COG1842	Phage shock protein A
NX823_17365	COG4758	membrane
NX823_17370	COG2814	Major facilitator Superfamily
NX823_17375	COG2096	Adenosyltransferase
NX823_17380	COG1120	ATPase activity
NX823_17385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX823_17390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX823_17395	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_17400	COG3386	PFAM SMP-30 Gluconolaconase
NX823_17405	COG2205	protein histidine kinase activity
NX823_17410	COG0745	RESPONSE REGULATOR receiver
NX823_17420	COG1191	sigma factor activity
NX823_17430	COG2140	Oxalate decarboxylase
NX823_17440	COG0577	efflux transmembrane transporter activity
NX823_17445	COG1136	(ABC) transporter
NX823_17450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX823_17455	COG1120	ATPase activity
NX823_17460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX823_17465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NX823_17470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX823_17475	COG0531	amino acid
NX823_17485	COG1988	membrane-bound metal-dependent
NX823_17490	COG1368	sulfuric ester hydrolase activity
NX823_17495	COG1910	domain protein
NX823_17500	COG0725	ABC transporter, periplasmic molybdate-binding protein
NX823_17505	COG4149	molybdate abc transporter
NX823_17510	COG0656	L-ascorbic acid biosynthetic process
NX823_17520	COG0025	NhaP-type Na H and K H
NX823_17525	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NX823_17530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX823_17535	COG3973	AAA domain
NX823_17540	COG2860	membrane
NX823_17545	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NX823_17550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NX823_17555	COG2217	Heavy metal translocating P-type atpase
NX823_17560	COG2217	Heavy metal translocating P-type atpase
NX823_17565	COG2608	mercury ion transmembrane transporter activity
NX823_17570	COG1937	Protein conserved in bacteria
NX823_17575	COG0673	inositol 2-dehydrogenase activity
NX823_17585	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_17595	COG5444	nuclease activity
NX823_17610	COG5632	N-Acetylmuramoyl-L-alanine amidase
NX823_17610	COG3409	Peptidoglycan-binding domain 1 protein
NX823_17615	COG4824	toxin secretion phage lysis holin
NX823_17640	COG3942	CHAP domain
NX823_17640	COG1705	Flagellar rod assembly protein muramidase FlgJ
NX823_17880	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NX823_17885	COG0557	exoribonuclease II activity
NX823_17890	COG1647	Serine aminopeptidase, S33
NX823_17895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NX823_17900	COG0596	Alpha beta hydrolase
NX823_17905	COG1476	TRANSCRIPTIONal
NX823_17910	COG1396	sequence-specific DNA binding
NX823_17915	COG1396	sequence-specific DNA binding
NX823_17920	COG1733	regulation of RNA biosynthetic process
NX823_17925	COG0840	transmembrane signaling receptor activity
NX823_17930	COG1174	glycine betaine transport
NX823_17935	COG1732	Glycine betaine
NX823_17940	COG1174	glycine betaine transport
NX823_17945	COG0517	IMP dehydrogenase activity
NX823_17945	COG1125	glycine betaine transport
NX823_17950	COG1510	regulation of RNA biosynthetic process
NX823_17955	COG1174	glycine betaine transport
NX823_17960	COG1732	Glycine betaine
NX823_17965	COG1174	glycine betaine transport
NX823_17970	COG0517	IMP dehydrogenase activity
NX823_17970	COG1125	glycine betaine transport
NX823_17975	COG1510	regulation of RNA biosynthetic process
NX823_17980	COG2095	MarC family integral membrane protein
NX823_17990	COG3064	Membrane
NX823_17995	COG4640	response to antibiotic
NX823_18000	COG0456	acetyltransferase
NX823_18005	COG0148	phosphopyruvate hydratase activity
NX823_18010	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NX823_18015	COG0149	triose-phosphate isomerase activity
NX823_18020	COG0126	phosphoglycerate kinase activity
NX823_18025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NX823_18030	COG2390	Transcriptional regulator
NX823_18035	COG2814	Major facilitator Superfamily
NX823_18040	COG1609	Transcriptional regulator
NX823_18045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX823_18050	COG0583	DNA-binding transcription factor activity
NX823_18055	COG0697	spore germination
NX823_18060	COG1113	amino acid transport
NX823_18070	COG1556	Lactate utilization protein
NX823_18075	COG1139	Iron-sulfur cluster binding protein
NX823_18080	COG0247	lactate metabolic process
NX823_18085	COG2197	response regulator
NX823_18090	COG4585	Histidine kinase
NX823_18095	COG0842	Transport permease protein
NX823_18100	COG1131	(ABC) transporter
NX823_18105	COG0596	Alpha beta hydrolase
NX823_18110	COG2208	phosphoserine phosphatase activity
NX823_18115	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NX823_18120	COG1874	Beta-galactosidase
NX823_18125	COG3833	ABC-type maltose transport systems, permease component
NX823_18130	COG1175	transmembrane transport
NX823_18135	COG2182	Extracellular solute-binding protein
NX823_18140	COG1609	Transcriptional regulator
NX823_18145	COG2186	Transcriptional regulator
NX823_18150	COG1620	l-lactate permease
NX823_18155	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NX823_18165	COG5039	Polysaccharide pyruvyl transferase
NX823_18170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NX823_18175	COG0110	maltose O-acetyltransferase activity
NX823_18180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NX823_18185	COG2244	polysaccharide biosynthetic process
NX823_18190	COG1216	Glycosyl transferase, family 2
NX823_18195	COG5039	Polysaccharide pyruvyl transferase
NX823_18200	COG1216	Glycosyl transferase, family 2
NX823_18210	COG0438	transferase activity, transferring glycosyl groups
NX823_18215	COG1215	transferase activity, transferring glycosyl groups
NX823_18220	COG0438	transferase activity, transferring glycosyl groups
NX823_18225	COG1086	Polysaccharide biosynthesis protein
NX823_18230	COG0489	protein tyrosine kinase activity
NX823_18235	COG3944	biosynthesis protein
NX823_18240	COG1396	sequence-specific DNA binding
NX823_18245	COG2272	Belongs to the type-B carboxylesterase lipase family
NX823_18255	COG3479	Phenolic acid decarboxylase
NX823_18270	COG1794	racemase activity, acting on amino acids and derivatives
NX823_18280	COG1621	beta-fructofuranosidase activity
NX823_18285	COG1621	beta-fructofuranosidase activity
NX823_18290	COG0531	amino acid
NX823_18295	COG1309	transcriptional regulator
NX823_18300	COG2076	Multidrug Resistance protein
NX823_18305	COG2076	Multidrug Resistance protein
NX823_18320	COG0740	serine-type endopeptidase activity
NX823_18325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NX823_18330	COG0366	Alpha amylase catalytic
NX823_18335	COG1554	hydrolase, family 65, central catalytic
NX823_18340	COG5521	maltodextrose utilization protein MalA
NX823_18350	COG1175	transmembrane transport
NX823_18355	COG2182	Extracellular solute-binding protein
NX823_18365	COG1609	Transcriptional regulator
NX823_18370	COG1611	Belongs to the LOG family
NX823_18375	COG1694	Mazg nucleotide pyrophosphohydrolase
NX823_18380	COG0659	secondary active sulfate transmembrane transporter activity
NX823_18385	COG0288	reversible hydration of carbon dioxide
NX823_18390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NX823_18395	COG0577	efflux transmembrane transporter activity
NX823_18400	COG1136	(ABC) transporter
NX823_18405	COG5002	protein histidine kinase activity
NX823_18410	COG0745	RESPONSE REGULATOR receiver
NX823_18420	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NX823_18425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX823_18430	COG1481	regulation of sporulation
NX823_18435	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NX823_18440	COG1660	Displays ATPase and GTPase activities
NX823_18445	COG1051	belongs to the nudix hydrolase family
NX823_18450	COG0492	ferredoxin-NADP+ reductase activity
NX823_18455	COG3883	PFAM NLP P60 protein
NX823_18455	COG0791	NLP P60 protein
NX823_18460	COG0457	Tetratricopeptide repeat
NX823_18465	COG1132	(ABC) transporter
NX823_18485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NX823_18485	COG0140	phosphoribosyl-ATP diphosphatase activity
NX823_18490	COG0107	imidazoleglycerol-phosphate synthase activity
NX823_18495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NX823_18500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NX823_18505	COG0131	Imidazoleglycerol-phosphate dehydratase
NX823_18510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NX823_18515	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NX823_18520	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NX823_18525	COG4990	cell redox homeostasis
NX823_18530	COG5297	Belongs to the glycosyl hydrolase family 6
NX823_18535	COG0110	maltose O-acetyltransferase activity
NX823_18540	COG0546	phosphoglycolate phosphatase activity
NX823_18545	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NX823_18550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NX823_18555	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NX823_18560	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NX823_18565	COG0363	glucosamine-6-phosphate deaminase activity
NX823_18570	COG2188	Transcriptional regulator
NX823_18575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NX823_18585	COG1950	PFAM Membrane protein of
NX823_18590	COG1983	PspC domain protein
NX823_18595	COG3595	metallopeptidase activity
NX823_18610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NX823_18615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NX823_18620	COG0556	nucleotide-excision repair
NX823_18625	COG4897	Protein conserved in bacteria
NX823_18630	COG0574	Belongs to the PEP-utilizing enzyme family
NX823_18630	COG3848	Pyruvate phosphate dikinase
NX823_18635	COG1309	transcriptional regulator
NX823_18640	COG2814	Major facilitator Superfamily
NX823_18645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX823_18655	COG0793	Belongs to the peptidase S41A family
NX823_18655	COG3409	Peptidoglycan-binding domain 1 protein
NX823_18660	COG2177	Part of the ABC transporter FtsEX involved in
NX823_18665	COG2884	Cell division ATP-binding protein ftsE
NX823_18670	COG2010	Cytochrome c
NX823_18675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX823_18685	COG0653	protein targeting
NX823_18695	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NX823_18710	COG1516	flagellar protein fliS
NX823_18715	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NX823_18720	COG1334	flagellar protein FlaG
NX823_18725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NX823_18730	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NX823_18735	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NX823_18745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NX823_18750	COG4786	Flagellar basal body rod
NX823_18750	COG1256	bacterial-type flagellum assembly
NX823_18755	COG3418	PFAM FlgN family protein
NX823_18760	COG2747	anti-sigma28 factor FlgM
NX823_18770	COG1040	competence protein
NX823_18780	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NX823_18785	COG1307	EDD domain protein, DegV family
NX823_18790	COG2197	response regulator
NX823_18795	COG4585	Histidine kinase
NX823_18800	COG1739	Uncharacterized protein family UPF0029
NX823_18835	COG1131	(ABC) transporter
NX823_18845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NX823_18850	COG0438	transferase activity, transferring glycosyl groups
NX823_18855	COG1215	transferase activity, transferring glycosyl groups
NX823_18860	COG3206	protein involved in exopolysaccharide biosynthesis
NX823_18865	COG3307	-O-antigen
NX823_18870	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NX823_18875	COG0438	transferase activity, transferring glycosyl groups
NX823_18875	COG0297	glycogen (starch) synthase activity
NX823_18880	COG2244	polysaccharide biosynthetic process
NX823_18890	COG2247	cell wall binding repeat
NX823_18890	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX823_18895	COG2247	cell wall binding repeat
NX823_18895	COG2385	sporulation resulting in formation of a cellular spore
NX823_18910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NX823_18915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NX823_18930	COG1682	transport, permease protein
NX823_18940	COG0463	Glycosyl transferase, family 2
NX823_18940	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NX823_18945	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NX823_18950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NX823_18955	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NX823_18960	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NX823_18965	COG4193	domain, Protein
NX823_18970	COG1482	cell wall glycoprotein biosynthetic process
NX823_18995	COG1316	TRANSCRIPTIONal
NX823_19000	COG0561	phosphatase activity
NX823_19005	COG0791	NLP P60 protein
NX823_19015	COG2843	Capsule synthesis protein
NX823_19025	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NX823_19030	COG1609	Transcriptional regulator
NX823_19035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX823_19040	COG1869	D-ribose catabolic process
NX823_19045	COG1129	ABC transporter
NX823_19050	COG1172	Belongs to the binding-protein-dependent transport system permease family
NX823_19055	COG1879	ABC-type sugar transport system periplasmic component
NX823_19060	COG3103	Sh3 type 3 domain protein
NX823_19075	COG2249	NAD(P)H dehydrogenase (quinone) activity
NX823_19080	COG3527	Alpha-acetolactate decarboxylase
NX823_19085	COG0028	Belongs to the TPP enzyme family
NX823_19090	COG0583	DNA-binding transcription factor activity
NX823_19095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NX823_19110	COG5337	Spore coat protein CotH
NX823_19120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NX823_19130	COG0405	Gamma-glutamyltransferase
NX823_19135	COG1522	sequence-specific DNA binding
NX823_19140	COG2059	Chromate
NX823_19145	COG2059	Chromate
NX823_19160	COG0655	NAD(P)H dehydrogenase (quinone) activity
NX823_19165	COG0583	DNA-binding transcription factor activity
NX823_19220	COG3878	Protein conserved in bacteria
NX823_19225	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NX823_19230	COG4464	protein tyrosine phosphatase activity
NX823_19235	COG0489	protein tyrosine kinase activity
NX823_19240	COG3944	biosynthesis protein
NX823_19250	COG4715	Zinc finger, swim domain protein
NX823_19255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NX823_19260	COG0561	phosphatase activity
NX823_19265	COG1349	DNA-binding transcription factor activity
NX823_19270	COG0629	single-stranded DNA binding
NX823_19290	COG0745	RESPONSE REGULATOR receiver
NX823_19290	COG2972	Histidine kinase
NX823_19295	COG1970	mechanosensitive ion channel activity
NX823_19300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NX823_19305	COG0457	Tetratricopeptide repeat
NX823_19310	COG4786	Flagellar basal body rod
NX823_19315	COG4786	Flagellar basal body rod
NX823_19320	COG1077	Cell shape determining protein MreB Mrl
NX823_19325	COG1609	Transcriptional regulator
NX823_19335	COG1846	Transcriptional regulator
NX823_19340	COG2814	Major facilitator Superfamily
NX823_19345	COG3420	alginic acid biosynthetic process
NX823_19350	COG1953	Uracil, thiamine, allantoin
NX823_19355	COG0477	Major facilitator Superfamily
NX823_19360	COG1335	isochorismatase
NX823_19370	COG0004	ammonium transporteR
NX823_19375	COG0347	Belongs to the P(II) protein family
NX823_19380	COG0671	phosphoesterase, PA-phosphatase related
NX823_19390	COG0739	heme binding
NX823_19395	COG1247	-acetyltransferase
NX823_19405	COG2089	acid synthase
NX823_19415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX823_19420	COG0789	Transcriptional regulator
NX823_19435	COG1959	2 iron, 2 sulfur cluster binding
NX823_19440	COG0804	urea catabolic process
NX823_19445	COG0832	Belongs to the urease beta subunit family
NX823_19450	COG0831	urea catabolic process
NX823_19465	COG3237	CsbD-like
NX823_19470	COG1994	Peptidase M50
NX823_19475	COG0457	Tetratricopeptide repeat
NX823_19480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NX823_19485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NX823_19495	COG2304	oxidoreductase activity
NX823_19505	COG2304	oxidoreductase activity
NX823_19510	COG2385	sporulation resulting in formation of a cellular spore
NX823_19515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NX823_19525	COG4836	Membrane
NX823_19535	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NX823_19540	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NX823_19545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NX823_19550	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NX823_19555	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NX823_19560	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NX823_19570	COG0356	it plays a direct role in the translocation of protons across the membrane
NX823_19580	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NX823_19585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NX823_19590	COG4475	Protein of unknown function (DUF436)
NX823_19595	COG0698	ribose 5-phosphate isomerase
NX823_19600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NX823_19605	COG1971	Probably functions as a manganese efflux pump
NX823_19610	COG0009	L-threonylcarbamoyladenylate synthase
NX823_19615	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NX823_19635	COG2890	protein-(glutamine-N5) methyltransferase activity
NX823_19640	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NX823_19645	COG0346	lactoylglutathione lyase activity
NX823_19650	COG0789	Transcriptional regulator
NX823_19660	COG0679	Auxin Efflux Carrier
NX823_19665	COG0281	malic enzyme
NX823_19670	COG1435	thymidine kinase activity
NX823_19680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NX823_19690	COG1494	fructose-1,6-bisphosphatase
NX823_19695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NX823_19705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NX823_19710	COG0191	fructose-bisphosphate aldolase activity
NX823_19715	COG2204	response regulator
NX823_19720	COG4821	SIS domain
NX823_19730	COG0504	CTP synthase activity
NX823_19735	COG3343	RNA polymerase activity
NX823_19740	COG1960	acyl-CoA dehydrogenase activity
NX823_19745	COG0247	lactate metabolic process
NX823_19745	COG2181	nitrate reductase activity
NX823_19750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX823_19755	COG4294	response to UV
NX823_19770	COG0018	arginyl-trna synthetase
NX823_19775	COG4506	Protein conserved in bacteria
NX823_19790	COG0535	radical SAM domain protein
NX823_19800	COG1131	(ABC) transporter
NX823_19805	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NX823_19810	COG0612	Peptidase, M16
NX823_19815	COG0612	Peptidase, M16
NX823_19825	COG3391	amine dehydrogenase activity
NX823_19835	COG0457	Tetratricopeptide repeat
NX823_19855	COG0010	Belongs to the arginase family
NX823_19860	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NX823_19865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NX823_19880	COG1994	Peptidase M50
NX823_19885	COG1942	4-Oxalocrotonate Tautomerase
NX823_19890	COG1846	Transcriptional regulator
NX823_19895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NX823_19900	COG0477	Major facilitator Superfamily
NX823_19905	COG1959	2 iron, 2 sulfur cluster binding
NX823_19910	COG3465	dGTPase activity
NX823_19915	COG1078	dGTPase activity
NX823_19920	COG4844	belongs to the
NX823_19930	COG0697	spore germination
NX823_19935	COG0095	Lipoate-protein ligase
NX823_19940	COG0583	DNA-binding transcription factor activity
NX823_19945	COG0280	phosphate acetyltransferase
NX823_19950	COG3253	May function as heme-dependent peroxidase
NX823_19955	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_19960	COG0436	Aminotransferase
NX823_19965	COG2814	Major facilitator Superfamily
NX823_19970	COG0151	Belongs to the GarS family
NX823_19975	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_19980	COG1917	Cupin 2, conserved barrel domain protein
NX823_19985	COG0077	Prephenate dehydratase
NX823_19995	COG2814	Major facilitator Superfamily
NX823_20000	COG0833	amino acid
NX823_20005	COG4187	Peptidase family M20/M25/M40
NX823_20010	COG1012	belongs to the aldehyde dehydrogenase family
NX823_20015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NX823_20025	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NX823_20030	COG1091	dTDP-4-dehydrorhamnose reductase activity
NX823_20035	COG1088	dTDP-glucose 4,6-dehydratase activity
NX823_20040	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NX823_20045	COG3980	spore coat polysaccharide biosynthesis protein
NX823_20050	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NX823_20055	COG2089	acid synthase
NX823_20060	COG0456	acetyltransferase
NX823_20065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NX823_20075	COG0463	Glycosyl transferase, family 2
NX823_20085	COG2363	Small membrane protein
NX823_20090	COG2233	PERMEase
NX823_20100	COG1012	belongs to the aldehyde dehydrogenase family
NX823_20105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NX823_20110	COG1216	Glycosyl transferase, family 2
NX823_20115	COG0351	phosphomethylpyrimidine kinase
NX823_20125	COG1621	beta-fructofuranosidase activity
NX823_20130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX823_20130	COG1263	PTS System
NX823_20135	COG2116	formate transmembrane transporter activity
NX823_20140	COG3711	transcriptional antiterminator
NX823_20150	COG1404	Belongs to the peptidase S8 family
NX823_20155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX823_20160	COG0778	Nitroreductase
NX823_20170	COG0772	Belongs to the SEDS family
NX823_20185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NX823_20190	COG1845	cytochrome c oxidase, subunit III
NX823_20195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NX823_20200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NX823_20205	COG2261	transglycosylase associated protein
NX823_20210	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NX823_20215	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NX823_20220	COG2246	polysaccharide biosynthetic process
NX823_20225	COG1309	transcriptional regulator
NX823_20235	COG3162	membrane
NX823_20240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX823_20245	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NX823_20250	COG2837	iron assimilation
NX823_20255	COG2822	iron ion transport
NX823_20260	COG0672	)-iron permease
NX823_20265	COG0352	thiamine-phosphate diphosphorylase activity
NX823_20270	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NX823_20275	COG0583	DNA-binding transcription factor activity
NX823_20280	COG1380	Effector of murein hydrolase LrgA
NX823_20285	COG1346	cytolysis
NX823_20290	COG2814	Major facilitator Superfamily
NX823_20295	COG4895	conserved protein (DUF2196)
NX823_20305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NX823_20310	COG0346	lactoylglutathione lyase activity
NX823_20320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NX823_20325	COG1404	Belongs to the peptidase S8 family
NX823_20330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NX823_20330	COG1263	PTS System
NX823_20335	COG3711	transcriptional antiterminator
NX823_20340	COG1442	glycosyl transferase family 8
NX823_20345	COG5522	Integral membrane protein (intg_mem_TP0381)
NX823_20350	COG1846	Transcriptional regulator
NX823_20355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NX823_20360	COG2234	aminopeptidase activity
NX823_20370	COG1575	Belongs to the MenA family. Type 1 subfamily
NX823_20385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NX823_20390	COG1696	Membrane protein involved in D-alanine export
NX823_20395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NX823_20400	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NX823_20405	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NX823_20410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX823_20415	COG1486	melibiose metabolic process
NX823_20420	COG1447	Phosphotransferase system cellobiose-specific component IIA
NX823_20425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NX823_20430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NX823_20435	COG3711	transcriptional antiterminator
NX823_20435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX823_20445	COG2094	Belongs to the DNA glycosylase MPG family
NX823_20450	COG0753	catalase activity
NX823_20455	COG2814	Major facilitator Superfamily
NX823_20460	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NX823_20465	COG1131	(ABC) transporter
NX823_20485	COG1595	DNA-templated transcription, initiation
NX823_20490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NX823_20495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NX823_20500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NX823_20505	COG4988	ABC transporter
NX823_20510	COG1294	oxidase, subunit
NX823_20515	COG1271	oxidase subunit
NX823_20520	COG3493	citrate carrier protein
NX823_20525	COG0501	Belongs to the peptidase M48B family
NX823_20535	COG0726	polysaccharide deacetylase
NX823_20540	COG3842	ATPase activity
NX823_20545	COG2508	Transcriptional regulator
NX823_20550	COG1012	belongs to the aldehyde dehydrogenase family
NX823_20555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NX823_20565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NX823_20575	COG4585	Histidine kinase
NX823_20580	COG2197	response regulator
NX823_20585	COG2195	Cleaves the N-terminal amino acid of tripeptides
NX823_20600	COG4894	glucomannan catabolic process
NX823_20605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NX823_20610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NX823_20615	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_20620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NX823_20625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NX823_20630	COG2610	gluconate transmembrane transporter activity
NX823_20635	COG0500	methyltransferase
NX823_20640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NX823_20655	COG0693	protein deglycase activity
NX823_20655	COG0753	catalase activity
NX823_20660	COG2851	Citrate transporter
NX823_20665	COG2273	Hydrolase Family 16
NX823_20670	COG3711	transcriptional antiterminator
NX823_20680	COG2270	Major facilitator Superfamily
NX823_20685	COG0513	Belongs to the DEAD box helicase family
NX823_20690	COG3401	FG-GAP repeat protein
NX823_20690	COG2755	lipolytic protein G-D-S-L family
NX823_20810	COG0697	spore germination
NX823_20815	COG0589	response to stress
NX823_20835	COG5444	nuclease activity
NX823_20870	COG3507	Belongs to the glycosyl hydrolase 43 family
NX823_20885	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NX823_20890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NX823_20895	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NX823_20900	COG2390	Transcriptional regulator
NX823_20910	COG3192	ethanolamine utilization protein
NX823_20915	COG2079	MmgE PrpD family protein
NX823_20920	COG1473	amidohydrolase
NX823_20925	COG1126	abc transporter atp-binding protein
NX823_20930	COG0765	amino acid transport
NX823_20935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NX823_20940	COG0456	acetyltransferase
NX823_20945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX823_20950	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NX823_20955	COG0561	phosphatase activity
NX823_20985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NX823_20990	COG5294	Protein conserved in bacteria
NX823_20995	COG0577	efflux transmembrane transporter activity
NX823_21000	COG1136	(ABC) transporter
NX823_21005	COG2205	protein histidine kinase activity
NX823_21015	COG0191	fructose-bisphosphate aldolase activity
NX823_21020	COG1082	Xylose isomerase domain protein TIM barrel
NX823_21025	COG1082	Xylose isomerase domain protein TIM barrel
NX823_21030	COG0673	inositol 2-dehydrogenase activity
NX823_21040	COG1082	Xylose isomerase domain protein TIM barrel
NX823_21045	COG3962	Belongs to the TPP enzyme family
NX823_21050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX823_21060	COG1012	belongs to the aldehyde dehydrogenase family
NX823_21065	COG1349	DNA-binding transcription factor activity
NX823_21070	COG0667	Aldo Keto reductase
NX823_21090	COG0326	Molecular chaperone. Has ATPase activity
NX823_21105	COG1309	transcriptional regulator
NX823_21110	COG1012	belongs to the aldehyde dehydrogenase family
NX823_21115	COG1714	RDD family
NX823_21125	COG1714	RDD family
NX823_21130	COG2311	Membrane
NX823_21135	COG1917	Cupin 2, conserved barrel domain protein
NX823_21140	COG1309	transcriptional regulator
NX823_21145	COG1028	Short-chain dehydrogenase reductase Sdr
NX823_21150	COG1846	Transcriptional regulator
NX823_21155	COG1380	Effector of murein hydrolase LrgA
NX823_21160	COG1346	cytolysis
NX823_21165	COG5039	Polysaccharide pyruvyl transferase
NX823_21175	COG1802	Transcriptional regulator
NX823_21180	COG1070	Carbohydrate kinase
NX823_21185	COG2610	gluconate transmembrane transporter activity
NX823_21190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NX823_21195	COG0450	alkyl hydroperoxide reductase
NX823_21200	COG3634	alkyl hydroperoxide reductase activity
NX823_21205	COG2723	6-phospho-beta-galactosidase activity
NX823_21210	COG2190	(PTS) system
NX823_21220	COG2188	Transcriptional regulator
NX823_21230	COG1131	(ABC) transporter
NX823_21235	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NX823_21245	COG0071	Belongs to the small heat shock protein (HSP20) family
NX823_21275	COG0210	DNA helicase
NX823_21320	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NX823_21335	COG1063	alcohol dehydrogenase
NX823_21355	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NX823_21360	COG0456	acetyltransferase
NX823_21375	COG0010	Belongs to the arginase family
NX823_21380	COG0833	amino acid
NX823_21385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NX823_21405	COG5658	integral membrane protein
NX823_21410	COG0640	Transcriptional regulator
NX823_21415	COG3829	transcription factor binding
NX823_21430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX823_21435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NX823_21440	COG4853	Protein conserved in bacteria
NX823_21445	COG4863	YycH protein
NX823_21450	COG5002	protein histidine kinase activity
NX823_21455	COG0745	RESPONSE REGULATOR receiver
NX823_21485	COG0346	lactoylglutathione lyase activity
NX823_21490	COG0305	Participates in initiation and elongation during chromosome replication
NX823_21505	COG3093	addiction module antidote protein HigA
NX823_21510	COG2807	transmembrane transport
NX823_21515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NX823_21520	COG0359	binds to the 23S rRNA
NX823_21525	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NX823_21555	COG1733	regulation of RNA biosynthetic process
NX823_21560	COG1227	inorganic diphosphatase activity
NX823_21585	COG4319	ketosteroid isomerase
NX823_21590	COG1357	PFAM Pentapeptide repeats (8 copies)
NX823_21605	COG1846	Transcriptional regulator
NX823_21610	COG2153	protein acetylation
NX823_21615	COG2364	Membrane
NX823_21620	COG0456	acetyltransferase
NX823_21625	COG2315	Protein conserved in bacteria
NX823_21630	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NX823_21640	COG2814	Major facilitator Superfamily
NX823_21655	COG3328	transposase activity
NX823_21675	COG0791	NLP P60 protein
NX823_21675	COG0741	lytic transglycosylase activity
NX823_21680	COG5644	endopeptidase inhibitor activity
NX823_21690	COG0433	COG0433 Predicted ATPase
NX823_21740	COG2946	Replication initiation factor
NX823_21745	COG1674	ftsk spoiiie
NX823_21775	COG1396	sequence-specific DNA binding
NX823_21780	COG2856	Zn peptidase
NX823_21785	COG0457	Tetratricopeptide repeat
NX823_21810	COG1331	Highly conserved protein containing a thioredoxin domain
NX823_21815	COG1331	Highly conserved protein containing a thioredoxin domain
NX823_21820	COG1266	CAAX protease self-immunity
NX823_21825	COG0477	Major facilitator Superfamily
NX823_21825	COG2814	Major facilitator Superfamily
NX823_21830	COG0110	maltose O-acetyltransferase activity
NX823_21835	COG0346	lactoylglutathione lyase activity
NX823_21840	COG1609	Transcriptional regulator
NX823_21845	COG0708	Exodeoxyribonuclease III
NX823_21850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NX823_21855	COG0629	single-stranded DNA binding
NX823_21860	COG0360	Binds together with S18 to 16S ribosomal RNA
NX823_21865	COG0012	GTP binding
NX823_21870	COG0243	molybdopterin cofactor binding
NX823_21875	COG4481	Protein conserved in bacteria
NX823_21880	COG3949	Membrane
NX823_21890	COG1475	DNA binding
NX823_21895	COG1192	Involved in chromosome partitioning
NX823_21905	COG1475	DNA binding
NX823_21910	COG0357	Ribosomal RNA small subunit methyltransferase G
NX823_21915	COG0445	tRNA wobble uridine modification
NX823_21920	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NX823_21925	COG1847	R3H domain protein
NX823_21930	COG0706	membrane insertase activity
NX823_21935	COG0594	ribonuclease P activity