locus-tag	class	description
A3772_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A3772_00010	COG0592	DNA-directed DNA polymerase activity
A3772_00015	COG2501	S4 domain
A3772_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A3772_00030	COG0187	DNA topoisomerase II activity
A3772_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A3772_00070	COG0516	GMP reductase activity
A3772_00070	COG0517	IMP dehydrogenase activity
A3772_00075	COG1686	Belongs to the peptidase S11 family
A3772_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A3772_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A3772_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A3772_00100	COG1428	Deoxynucleoside kinase
A3772_00105	COG1428	Deoxynucleoside kinase
A3772_00110	COG3858	chitin binding
A3772_00110	COG1388	LysM domain
A3772_00115	COG1335	isochorismatase
A3772_00120	COG0590	tRNA wobble adenosine to inosine editing
A3772_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A3772_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A3772_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A3772_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
A3772_00190	COG3853	Toxic anion resistance protein (TelA)
A3772_00195	COG1982	Orn Lys Arg decarboxylase major
A3772_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A3772_00205	COG3870	Protein conserved in bacteria
A3772_00210	COG1728	Protein conserved in bacteria
A3772_00215	COG0470	DNA polymerase III
A3772_00220	COG1774	PSP1 C-terminal conserved region
A3772_00225	COG4467	Involved in initiation control of chromosome replication
A3772_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A3772_00235	COG2827	Endonuclease containing a URI domain
A3772_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A3772_00245	COG2002	toxin-antitoxin pair type II binding
A3772_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3772_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3772_00255	COG0084	hydrolase, TatD family'
A3772_00260	COG3583	domain protein
A3772_00260	COG3584	3D domain protein
A3772_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A3772_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A3772_00280	COG4466	Protein conserved in bacteria
A3772_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A3772_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3772_00300	COG0251	oxidation-reduction process
A3772_00305	COG2088	sporulation resulting in formation of a cellular spore
A3772_00315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A3772_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3772_00325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A3772_00330	COG0193	aminoacyl-tRNA hydrolase activity
A3772_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A3772_00345	COG2002	toxin-antitoxin pair type II binding
A3772_00350	COG2244	polysaccharide biosynthetic process
A3772_00355	COG3956	TIGRFAM MazG family protein
A3772_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A3772_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
A3772_00380	COG1098	S1 RNA binding domain
A3772_00395	COG2208	phosphoserine phosphatase activity
A3772_00400	COG2304	oxidoreductase activity
A3772_00405	COG0515	serine threonine protein kinase
A3772_00410	COG0037	tRNA processing
A3772_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3772_00425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A3772_00430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A3772_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A3772_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3772_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A3772_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
A3772_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3772_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A3772_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A3772_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A3772_00475	COG1396	sequence-specific DNA binding
A3772_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A3772_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A3772_00570	COG4463	regulation of RNA biosynthetic process
A3772_00575	COG3880	PFAM UvrB UvrC protein
A3772_00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
A3772_00585	COG0542	response to heat
A3772_00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A3772_00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A3772_00600	COG4956	integral membrane protein (PIN domain superfamily)
A3772_00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A3772_00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A3772_00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3772_00625	COG1045	serine acetyltransferase
A3772_00630	COG0215	cysteine-tRNA ligase activity
A3772_00635	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A3772_00640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A3772_00645	COG3688	RNA-binding protein containing a PIN domain
A3772_00650	COG1595	DNA-templated transcription, initiation
A3772_00655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A3772_00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A3772_00665	COG0250	Participates in transcription elongation, termination and antitermination
A3772_00670	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A3772_00675	COG0081	regulation of translation
A3772_00680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A3772_00685	COG0222	ribosome binding
A3772_00690	COG2813	Specifically methylates the guanine in position
A3772_00695	COG0085	RNA polymerase activity
A3772_00700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3772_00705	COG1358	cellular component organization or biogenesis
A3772_00710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A3772_00715	COG0049	tRNA binding
A3772_00720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A3772_00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A3772_00730	COG0596	Alpha beta hydrolase
A3772_00735	COG0051	transcription antitermination factor activity, RNA binding
A3772_00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3772_00745	COG0088	Forms part of the polypeptide exit tunnel
A3772_00750	COG0089	rRNA binding
A3772_00755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3772_00760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A3772_00765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A3772_00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A3772_00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A3772_00780	COG0255	Belongs to the universal ribosomal protein uL29 family
A3772_00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A3772_00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A3772_00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3772_00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3772_00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A3772_00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3772_00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A3772_00830	COG1841	ribosomal large subunit assembly
A3772_00835	COG0200	Binds to the 23S rRNA
A3772_00840	COG0201	protein transport
A3772_00845	COG0563	adenylate kinase activity
A3772_00850	COG0024	Methionine aminopeptidase
A3772_00855	COG2163	COG2163 Ribosomal protein L14E L6E L27E
A3772_00860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A3772_00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A3772_00870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3772_00875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A3772_00880	COG0202	RNA polymerase activity
A3772_00885	COG0203	ribosomal protein L17
A3772_00890	COG1122	ATPase activity
A3772_00895	COG1122	ATPase activity
A3772_00900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A3772_00905	COG0101	tRNA pseudouridine synthase activity
A3772_00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A3772_00915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A3772_00920	COG2226	methyltransferase
A3772_00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3772_00935	COG0489	protein tyrosine kinase activity
A3772_00945	COG2194	sulfuric ester hydrolase activity
A3772_00950	COG0726	polysaccharide deacetylase
A3772_01035	COG0659	secondary active sulfate transmembrane transporter activity
A3772_01040	COG0385	Bile acid
A3772_01045	COG2819	hydrolase of the alpha beta superfamily
A3772_01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3772_01055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3772_01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3772_01065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3772_01065	COG2207	Transcriptional regulator
A3772_01070	COG3876	Protein conserved in bacteria
A3772_01075	COG1472	Belongs to the glycosyl hydrolase 3 family
A3772_01080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3772_01085	COG1263	PTS System
A3772_01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3772_01090	COG1737	Transcriptional regulator
A3772_01095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A3772_01100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3772_01105	COG1683	Conserved Protein
A3772_01135	COG1595	DNA-templated transcription, initiation
A3772_01140	COG5662	AntiSigma factor
A3772_01145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A3772_01150	COG4856	YbbR-like protein
A3772_01155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3772_01160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3772_01165	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A3772_01170	COG2169	Transcriptional regulator
A3772_01175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3772_01180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3772_01185	COG3002	Belongs to the UPF0753 family
A3772_01190	COG0288	reversible hydration of carbon dioxide
A3772_01200	COG5609	conserved protein (DUF2294)
A3772_01210	COG0640	Transcriptional regulator
A3772_01215	COG2814	Major facilitator Superfamily
A3772_01220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3772_01230	COG0535	radical SAM domain protein
A3772_01235	COG1266	CAAX protease self-immunity
A3772_01240	COG1131	(ABC) transporter
A3772_01250	COG1413	lyase activity
A3772_01255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_01260	COG0596	Alpha beta hydrolase
A3772_01265	COG0745	RESPONSE REGULATOR receiver
A3772_01270	COG0642	Histidine kinase
A3772_01280	COG0515	serine threonine protein kinase
A3772_01295	COG1113	amino acid transport
A3772_01310	COG2602	Beta-lactamase
A3772_01315	COG2124	cytochrome p450
A3772_01325	COG0531	amino acid
A3772_01330	COG0584	glycerophosphoryl diester phosphodiesterase
A3772_01335	COG2271	Major facilitator Superfamily
A3772_01345	COG0456	acetyltransferase
A3772_01345	COG1846	Transcriptional regulator
A3772_01350	COG2271	Major facilitator Superfamily
A3772_01365	COG3409	Peptidoglycan-binding domain 1 protein
A3772_01370	COG0697	spore germination
A3772_01375	COG1917	Cupin 2, conserved barrel domain protein
A3772_01375	COG2207	Transcriptional regulator
A3772_01380	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A3772_01385	COG3591	Belongs to the peptidase S1B family
A3772_01395	COG0596	Alpha beta hydrolase
A3772_01400	COG1183	phosphatidylcholine synthase activity
A3772_01405	COG0586	Pfam SNARE associated Golgi protein
A3772_01410	COG0688	phosphatidylethanolamine metabolic process
A3772_01420	COG2312	Erythromycin esterase
A3772_01425	COG2207	Transcriptional regulator
A3772_01435	COG1301	dicarboxylic acid transport
A3772_01440	COG1263	PTS System
A3772_01440	COG2190	(PTS) system
A3772_01440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3772_01445	COG0363	glucosamine-6-phosphate deaminase activity
A3772_01460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3772_01465	COG0833	amino acid
A3772_01470	COG2040	homocysteine
A3772_01480	COG1115	amino acid carrier protein
A3772_01485	COG2066	Belongs to the glutaminase family
A3772_01490	COG4191	Histidine kinase
A3772_01495	COG0784	Response regulator, receiver
A3772_01500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3772_01505	COG1012	belongs to the aldehyde dehydrogenase family
A3772_01510	COG2271	Major facilitator Superfamily
A3772_01515	COG4948	Mandelate Racemase Muconate Lactonizing
A3772_01520	COG2186	Transcriptional regulator
A3772_01525	COG2721	sulfolactate sulfo-lyase activity
A3772_01530	COG3173	Aminoglycoside phosphotransferase
A3772_01540	COG0697	spore germination
A3772_01545	COG0745	RESPONSE REGULATOR receiver
A3772_01550	COG2205	protein histidine kinase activity
A3772_01555	COG1131	(ABC) transporter
A3772_01575	COG3773	Cell wall hydrolase
A3772_01580	COG2304	oxidoreductase activity
A3772_01590	COG3540	Alkaline phosphatase
A3772_01595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A3772_01600	COG0805	protein transport
A3772_01605	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A3772_01610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3772_01615	COG0477	Major facilitator Superfamily
A3772_01620	COG1309	transcriptional regulator
A3772_01625	COG0252	asparaginase activity
A3772_01630	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A3772_01635	COG1714	RDD family
A3772_01640	COG3012	SEC-C Motif Domain Protein
A3772_01640	COG1405	negative regulation of cell septum assembly
A3772_01645	COG3290	protein histidine kinase activity
A3772_01650	COG3279	Response regulator of the LytR AlgR family
A3772_01655	COG4555	ABC transporter
A3772_01660	COG1668	transmembrane transport
A3772_01665	COG0667	Aldo Keto reductase
A3772_01675	COG1595	DNA-templated transcription, initiation
A3772_01680	COG1595	DNA-templated transcription, initiation
A3772_01685	COG1876	peptidase activity
A3772_01690	COG0457	Tetratricopeptide repeat
A3772_01695	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_01700	COG0366	Alpha amylase catalytic
A3772_01705	COG0803	Belongs to the bacterial solute-binding protein 9 family
A3772_01710	COG1121	(ABC) transporter
A3772_01715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A3772_01720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3772_01725	COG2310	stress, protein
A3772_01730	COG2310	stress, protein
A3772_01735	COG2310	stress, protein
A3772_01740	COG0861	Integral membrane protein TerC family
A3772_01750	COG3853	Toxic anion resistance protein (TelA)
A3772_01755	COG0477	Major facilitator Superfamily
A3772_01760	COG2814	Major facilitator Superfamily
A3772_01765	COG0640	Transcriptional regulator
A3772_01770	COG0517	IMP dehydrogenase activity
A3772_01770	COG4175	Glycine betaine
A3772_01775	COG4176	ABC-type proline glycine betaine transport system permease component
A3772_01780	COG2113	Glycine betaine
A3772_01785	COG1473	amidohydrolase
A3772_01790	COG1288	antiporter activity
A3772_01805	COG0366	Alpha amylase catalytic
A3772_01810	COG0039	L-malate dehydrogenase activity
A3772_01815	COG1620	l-lactate permease
A3772_01820	COG2814	Major facilitator Superfamily
A3772_01825	COG1846	Transcriptional regulator
A3772_01830	COG1280	lysine exporter protein (LysE YggA)
A3772_01835	COG3403	YqcI/YcgG family
A3772_01840	COG1113	amino acid transport
A3772_01845	COG3665	Urea carboxylase-associated protein
A3772_01850	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A3772_01855	COG1660	Displays ATPase and GTPase activities
A3772_01860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3772_01865	COG2226	methyltransferase
A3772_01870	COG0583	DNA-binding transcription factor activity
A3772_01875	COG3458	cephalosporin-C deacetylase activity
A3772_01880	COG3541	Predicted nucleotidyltransferase
A3772_01885	COG0506	proline dehydrogenase activity
A3772_01890	COG1012	belongs to the aldehyde dehydrogenase family
A3772_01895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3772_01900	COG2508	Transcriptional regulator
A3772_01905	COG3689	TIGRFAM TIGR03943 family protein
A3772_01910	COG0701	Predicted permease
A3772_01915	COG2267	carboxylic ester hydrolase activity
A3772_01920	COG0492	ferredoxin-NADP+ reductase activity
A3772_01925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A3772_01925	COG1587	Uroporphyrinogen-III synthase
A3772_01930	COG2146	nitrite reductase [NAD(P)H] activity
A3772_01935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3772_01940	COG0243	molybdopterin cofactor binding
A3772_01945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3772_01950	COG2223	nitrite transmembrane transporter activity
A3772_01955	COG1469	GTP cyclohydrolase I activity
A3772_01960	COG1376	ErfK ybiS ycfS ynhG family protein
A3772_01970	COG0523	cobalamin synthesis protein
A3772_01975	COG0765	amino acid transport
A3772_01980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3772_01990	COG1714	RDD family
A3772_02000	COG2723	6-phospho-beta-galactosidase activity
A3772_02010	COG3209	COG3209 Rhs family protein
A3772_02015	COG0840	transmembrane signaling receptor activity
A3772_02015	COG3290	protein histidine kinase activity
A3772_02020	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A3772_02025	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A3772_02030	COG1733	regulation of RNA biosynthetic process
A3772_02040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_02045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_02050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_02055	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A3772_02060	COG2814	Major facilitator Superfamily
A3772_02070	COG0697	spore germination
A3772_02075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3772_02085	COG2364	Membrane
A3772_02090	COG1126	abc transporter atp-binding protein
A3772_02095	COG0765	amino acid transport
A3772_02100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3772_02105	COG0583	DNA-binding transcription factor activity
A3772_02110	COG0163	prenyltransferase activity
A3772_02115	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A3772_02130	COG0596	Alpha beta hydrolase
A3772_02135	COG3104	oligopeptide transport
A3772_02140	COG5434	Belongs to the glycosyl hydrolase 28 family
A3772_02150	COG0697	spore germination
A3772_02160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A3772_02165	COG1136	(ABC) transporter
A3772_02170	COG0577	efflux transmembrane transporter activity
A3772_02175	COG0745	RESPONSE REGULATOR receiver
A3772_02180	COG3850	Histidine kinase
A3772_02180	COG5002	protein histidine kinase activity
A3772_02185	COG0457	Tetratricopeptide repeat
A3772_02200	COG0527	aspartate kinase activity
A3772_02205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3772_02210	COG4605	iron ion homeostasis
A3772_02215	COG4604	ABC transporter, ATP-binding protein
A3772_02220	COG4607	ABC-type enterochelin transport system periplasmic component
A3772_02225	COG2814	Major facilitator Superfamily
A3772_02230	COG1309	transcriptional regulator
A3772_02235	COG0778	Nitroreductase
A3772_02240	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A3772_02245	COG0640	Transcriptional regulator
A3772_02250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3772_02255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3772_02260	COG1012	belongs to the aldehyde dehydrogenase family
A3772_02265	COG4975	Glucose uptake
A3772_02270	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_02275	COG4549	nuclear export factor GLE1
A3772_02285	COG1349	DNA-binding transcription factor activity
A3772_02295	COG2213	PTS system mannitol-specific
A3772_02300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3772_02305	COG0246	Mannitol dehydrogenase
A3772_02310	COG0473	3-isopropylmalate dehydrogenase activity
A3772_02315	COG0681	Belongs to the peptidase S26 family
A3772_02325	COG0412	Dienelactone hydrolase
A3772_02330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A3772_02340	COG0561	phosphatase activity
A3772_02345	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A3772_02350	COG1914	H( )-stimulated, divalent metal cation uptake system
A3772_02355	COG4336	lyase activity
A3772_02360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3772_02365	COG1984	allophanate hydrolase subunit 2
A3772_02370	COG1414	Transcriptional regulator
A3772_02375	COG2755	lipolytic protein G-D-S-L family
A3772_02385	COG2329	Antibiotic biosynthesis monooxygenase
A3772_02390	COG0768	penicillin binding
A3772_02395	COG4989	oxidoreductase activity
A3772_02400	COG3711	transcriptional antiterminator
A3772_02405	COG0318	PFAM AMP-dependent synthetase and ligase
A3772_02410	COG2226	methyltransferase
A3772_02415	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_02420	COG1917	Cupin 2, conserved barrel domain protein
A3772_02425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3772_02430	COG3871	stress protein (general stress protein 26)
A3772_02440	COG2814	Major facilitator Superfamily
A3772_02445	COG1522	sequence-specific DNA binding
A3772_02450	COG0551	DNA topoisomerase type I activity
A3772_02450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3772_02455	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A3772_02460	COG3706	GGDEF domain
A3772_02465	COG5298	Protein conserved in bacteria
A3772_02470	COG1215	transferase activity, transferring glycosyl groups
A3772_02480	COG0531	amino acid
A3772_02485	COG0494	nUDIX hydrolase
A3772_02490	COG0028	Belongs to the TPP enzyme family
A3772_02505	COG1914	H( )-stimulated, divalent metal cation uptake system
A3772_02510	COG2261	transglycosylase associated protein
A3772_02515	COG4876	unkown
A3772_02520	COG2217	Heavy metal translocating P-type atpase
A3772_02525	COG3729	General stress protein
A3772_02530	COG0662	Cupin 2, conserved barrel domain protein
A3772_02535	COG2329	Antibiotic biosynthesis monooxygenase
A3772_02540	COG3546	catalase activity
A3772_02545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A3772_02550	COG3290	protein histidine kinase activity
A3772_02555	COG4565	transcriptional regulatory protein
A3772_02560	COG1301	dicarboxylic acid transport
A3772_02565	COG0628	permease
A3772_02575	COG1131	(ABC) transporter
A3772_02580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A3772_02590	COG1960	acyl-CoA dehydrogenase activity
A3772_02605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A3772_02610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_02615	COG1181	Belongs to the D-alanine--D-alanine ligase family
A3772_02620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A3772_02625	COG0513	Belongs to the DEAD box helicase family
A3772_02630	COG3402	PFAM membrane-flanked domain
A3772_02635	COG3428	Bacterial PH domain
A3772_02640	COG0705	Rhomboid family
A3772_02645	COG0736	holo-[acyl-carrier-protein] synthase activity
A3772_02650	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A3772_02655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A3772_02660	COG0864	Transcriptional regulator
A3772_02665	COG2337	Toxic component of a toxin-antitoxin (TA) module
A3772_02670	COG1366	Belongs to the anti-sigma-factor antagonist family
A3772_02675	COG1366	Belongs to the anti-sigma-factor antagonist family
A3772_02680	COG2172	sigma factor antagonist activity
A3772_02685	COG2208	phosphoserine phosphatase activity
A3772_02690	COG1366	Belongs to the anti-sigma-factor antagonist family
A3772_02695	COG2172	sigma factor antagonist activity
A3772_02700	COG1191	sigma factor activity
A3772_02705	COG2208	phosphoserine phosphatase activity
A3772_02720	COG1673	EVE domain
A3772_02725	COG1846	Transcriptional regulator
A3772_02730	COG2183	response to ionizing radiation
A3772_02740	COG3091	SprT-like family
A3772_02780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3772_02785	COG1522	sequence-specific DNA binding
A3772_02790	COG1522	sequence-specific DNA binding
A3772_02795	COG1335	isochorismatase
A3772_02800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3772_02805	COG2814	Major facilitator Superfamily
A3772_02825	COG0693	protein deglycase activity
A3772_02830	COG1278	Cold shock
A3772_02835	COG1329	Transcriptional regulator
A3772_02840	COG0697	spore germination
A3772_02845	COG1917	Cupin 2, conserved barrel domain protein
A3772_02845	COG2207	Transcriptional regulator
A3772_02850	COG0697	spore germination
A3772_02855	COG2207	Transcriptional regulator
A3772_02855	COG3708	Transcriptional regulator
A3772_02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3772_02865	COG0477	Major facilitator Superfamily
A3772_02875	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
A3772_02885	COG0697	spore germination
A3772_02890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3772_02895	COG2030	dehydratase
A3772_02900	COG3545	Serine hydrolase
A3772_02905	COG1733	regulation of RNA biosynthetic process
A3772_02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3772_02915	COG1733	regulation of RNA biosynthetic process
A3772_02920	COG2249	NAD(P)H dehydrogenase (quinone) activity
A3772_02925	COG2814	Major facilitator Superfamily
A3772_02930	COG1309	transcriptional regulator
A3772_02940	COG0640	Transcriptional regulator
A3772_02945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3772_02955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3772_02960	COG0697	spore germination
A3772_02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3772_02970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A3772_02975	COG0640	Transcriptional regulator
A3772_02980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3772_02990	COG4585	Histidine kinase
A3772_02995	COG2197	response regulator
A3772_03000	COG2409	Drug exporters of the RND superfamily
A3772_03005	COG0596	Alpha beta hydrolase
A3772_03010	COG1811	Na channel or pump
A3772_03015	COG0789	Transcriptional regulator
A3772_03015	COG4978	Transcriptional regulator
A3772_03020	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A3772_03025	COG0778	Nitroreductase
A3772_03030	COG0346	lactoylglutathione lyase activity
A3772_03035	COG2259	Doxx family
A3772_03040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_03060	COG2323	membrane
A3772_03065	COG2323	membrane
A3772_03070	COG0071	Belongs to the small heat shock protein (HSP20) family
A3772_03085	COG1309	transcriptional regulator
A3772_03095	COG0456	acetyltransferase
A3772_03105	COG1113	amino acid transport
A3772_03110	COG2318	DinB family
A3772_03115	COG1846	Transcriptional regulator
A3772_03120	COG2409	Drug exporters of the RND superfamily
A3772_03120	COG1033	growth of symbiont in host cell
A3772_03125	COG0778	Nitroreductase
A3772_03130	COG1846	Transcriptional regulator
A3772_03135	COG2814	Major facilitator Superfamily
A3772_03140	COG0730	response to heat
A3772_03145	COG1802	Transcriptional regulator
A3772_03150	COG1388	LysM domain
A3772_03150	COG3858	chitin binding
A3772_03155	COG1819	glycosyl
A3772_03165	COG1785	Belongs to the alkaline phosphatase family
A3772_03170	COG5646	InterPro IPR014922
A3772_03180	COG0454	-acetyltransferase
A3772_03185	COG1078	dGTPase activity
A3772_03190	COG1388	LysM domain
A3772_03195	COG2814	Major facilitator Superfamily
A3772_03200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3772_03205	COG1447	Phosphotransferase system cellobiose-specific component IIA
A3772_03210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3772_03215	COG2723	6-phospho-beta-galactosidase activity
A3772_03220	COG2188	Transcriptional regulator
A3772_03225	COG1940	carbohydrate kinase activity
A3772_03230	COG1482	cell wall glycoprotein biosynthetic process
A3772_03235	COG4124	Belongs to the glycosyl hydrolase 26 family
A3772_03280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A3772_03285	COG0802	atpase or kinase
A3772_03290	COG1214	PFAM Peptidase M22, glycoprotease
A3772_03295	COG0456	acetyltransferase
A3772_03300	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A3772_03305	COG0488	(ABC) transporter
A3772_03310	COG0315	cyclic pyranopterin monophosphate synthase activity
A3772_03315	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
A3772_03320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A3772_03325	COG0805	protein transport
A3772_03335	COG1266	CAAX protease self-immunity
A3772_03340	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A3772_03345	COG0459	protein refolding
A3772_03360	COG3378	Phage plasmid primase P4 family
A3772_03375	COG0270	DNA (cytosine-5-)-methyltransferase activity
A3772_03380	COG0270	DNA (cytosine-5-)-methyltransferase activity
A3772_03385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3772_03405	COG1401	restriction endodeoxyribonuclease activity
A3772_03425	COG0457	Tetratricopeptide repeat
A3772_03430	COG1063	alcohol dehydrogenase
A3772_03435	COG2211	Major facilitator Superfamily
A3772_03440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3772_03445	COG1842	Phage shock protein A
A3772_03450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A3772_03455	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A3772_03460	COG4260	virion core protein, lumpy skin disease virus
A3772_03470	COG2814	Major facilitator Superfamily
A3772_03475	COG1063	alcohol dehydrogenase
A3772_03480	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A3772_03485	COG0823	Involved in the tonB-independent uptake of proteins
A3772_03500	COG2267	carboxylic ester hydrolase activity
A3772_03510	COG2132	Multicopper oxidase
A3772_03515	COG1113	amino acid transport
A3772_03525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A3772_03530	COG0714	Associated with various cellular activities
A3772_03535	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A3772_03540	COG1305	Transglutaminase-like
A3772_03545	COG0519	Catalyzes the synthesis of GMP from XMP
A3772_03545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3772_03550	COG2252	PERMEase
A3772_03555	COG3064	Membrane
A3772_03565	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
A3772_03575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3772_03580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A3772_03585	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3772_03590	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A3772_03595	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3772_03600	COG0047	phosphoribosylformylglycinamidine synthase activity
A3772_03605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3772_03610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A3772_03615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A3772_03620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A3772_03625	COG0138	bifunctional purine biosynthesis protein purh
A3772_03630	COG0151	Belongs to the GarS family
A3772_03635	COG1522	sequence-specific DNA binding
A3772_03640	COG0531	amino acid
A3772_03650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A3772_03655	COG1470	cell adhesion involved in biofilm formation
A3772_03660	COG4496	protein, YerC YecD
A3772_03665	COG0069	glutamate synthase activity
A3772_03675	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A3772_03680	COG0210	DNA helicase
A3772_03685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3772_03690	COG4851	CamS sex pheromone cAM373 precursor
A3772_03695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A3772_03700	COG1285	pathogenesis
A3772_03705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3772_03710	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3772_03715	COG0154	amidase activity
A3772_03720	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3772_03725	COG1309	transcriptional regulator
A3772_03730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A3772_03735	COG1597	lipid kinase activity
A3772_03740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3772_03745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A3772_03750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A3772_03755	COG1002	Type II restriction enzyme, methylase subunits
A3772_03760	COG1061	Type III restriction enzyme res subunit
A3772_03765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A3772_03785	COG5444	nuclease activity
A3772_03790	COG3391	amine dehydrogenase activity
A3772_03795	COG0457	Tetratricopeptide repeat
A3772_03805	COG0217	transcriptional regulatory protein
A3772_03815	COG1309	transcriptional regulator
A3772_03820	COG3631	Ketosteroid isomerase-related protein
A3772_03825	COG0702	epimerase
A3772_03840	COG3546	catalase activity
A3772_03845	COG0454	-acetyltransferase
A3772_03855	COG5578	integral membrane protein
A3772_03860	COG2972	Histidine kinase
A3772_03865	COG2207	Transcriptional regulator
A3772_03865	COG4753	response regulator
A3772_03870	COG1653	transport
A3772_03875	COG1175	transmembrane transport
A3772_03880	COG0395	ABC-type sugar transport system, permease component
A3772_03885	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A3772_03890	COG2207	Transcriptional regulator
A3772_03895	COG2755	lipolytic protein G-D-S-L family
A3772_03905	COG5578	integral membrane protein
A3772_03910	COG3401	FG-GAP repeat protein
A3772_03915	COG3401	FG-GAP repeat protein
A3772_03920	COG2755	lipolytic protein G-D-S-L family
A3772_03925	COG1874	Beta-galactosidase
A3772_03935	COG1653	transport
A3772_03940	COG4209	transmembrane transport
A3772_03945	COG0395	ABC-type sugar transport system, permease component
A3772_03950	COG1486	melibiose metabolic process
A3772_03955	COG2323	membrane
A3772_03960	COG2329	Antibiotic biosynthesis monooxygenase
A3772_03965	COG0346	lactoylglutathione lyase activity
A3772_03980	COG5583	Uncharacterized small protein (DUF2292)
A3772_03985	COG0670	Belongs to the BI1 family
A3772_03990	COG0697	spore germination
A3772_03995	COG1846	Transcriptional regulator
A3772_04000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3772_04010	COG2124	cytochrome p450
A3772_04010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A3772_04015	COG1368	sulfuric ester hydrolase activity
A3772_04020	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3772_04025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3772_04030	COG1442	glycosyl transferase family 8
A3772_04035	COG1216	Glycosyl transferase, family 2
A3772_04040	COG1442	glycosyl transferase family 8
A3772_04045	COG2223	nitrite transmembrane transporter activity
A3772_04050	COG1011	Hydrolase
A3772_04055	COG0531	amino acid
A3772_04060	COG1012	belongs to the aldehyde dehydrogenase family
A3772_04065	COG0840	transmembrane signaling receptor activity
A3772_04070	COG0488	(ABC) transporter
A3772_04080	COG0789	Transcriptional regulator
A3772_04085	COG2814	Major facilitator Superfamily
A3772_04100	COG0488	(ABC) transporter
A3772_04105	COG0513	Belongs to the DEAD box helicase family
A3772_04110	COG0456	acetyltransferase
A3772_04115	COG2130	NADP-dependent
A3772_04130	COG2211	Major facilitator Superfamily
A3772_04135	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A3772_04140	COG1120	ATPase activity
A3772_04145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3772_04150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3772_04155	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A3772_04170	COG3866	Pectate lyase
A3772_04175	COG0471	metal ion transport
A3772_04180	COG3290	protein histidine kinase activity
A3772_04185	COG4565	transcriptional regulatory protein
A3772_04190	COG3181	Tripartite tricarboxylate transporter family receptor
A3772_04200	COG2851	Citrate transporter
A3772_04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3772_04210	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A3772_04215	COG1254	Belongs to the acylphosphatase family
A3772_04220	COG2258	MOSC domain
A3772_04240	COG0024	Methionine aminopeptidase
A3772_04245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3772_04245	COG1263	PTS System
A3772_04250	COG1368	sulfuric ester hydrolase activity
A3772_04260	COG1115	amino acid carrier protein
A3772_04265	COG0531	amino acid
A3772_04280	COG0697	spore germination
A3772_04285	COG1263	PTS System
A3772_04285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3772_04290	COG0366	Alpha amylase catalytic
A3772_04295	COG2188	Transcriptional regulator
A3772_04300	COG0778	Nitroreductase
A3772_04305	COG0737	Belongs to the 5'-nucleotidase family
A3772_04310	COG0693	protein deglycase activity
A3772_04315	COG2814	Major facilitator Superfamily
A3772_04320	COG4840	Belongs to the UPF0435 family
A3772_04325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A3772_04330	COG4980	gas vesicle protein
A3772_04335	COG1295	ribonuclease BN
A3772_04345	COG0477	Major facilitator Superfamily
A3772_04355	COG0387	Pfam Sodium calcium exchanger
A3772_04365	COG0668	transmembrane transport
A3772_04370	COG0535	radical SAM domain protein
A3772_04380	COG0726	polysaccharide deacetylase
A3772_04385	COG2084	Dehydrogenase
A3772_04390	COG0598	Magnesium transport protein CorA
A3772_04395	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A3772_04400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3772_04410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A3772_04415	COG4637	Psort location Cytoplasmic, score
A3772_04425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A3772_04430	COG0022	dehydrogenase e1 component
A3772_04435	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3772_04440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A3772_04445	COG3284	Transcriptional regulator
A3772_04455	COG1742	UPF0060 membrane protein
A3772_04480	COG4842	Belongs to the WXG100 family
A3772_04485	COG1486	melibiose metabolic process
A3772_04490	COG1737	Transcriptional regulator
A3772_04495	COG1263	PTS System
A3772_04495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3772_04500	COG1132	(ABC) transporter
A3772_04505	COG1132	(ABC) transporter
A3772_04510	COG2259	Doxx family
A3772_04515	COG2514	catechol 2,3-dioxygenase activity
A3772_04520	COG1917	Cupin 2, conserved barrel domain protein
A3772_04520	COG4977	sequence-specific DNA binding
A3772_04525	COG2814	Major facilitator Superfamily
A3772_04530	COG1082	Xylose isomerase domain protein TIM barrel
A3772_04535	COG0673	inositol 2-dehydrogenase activity
A3772_04540	COG4585	Histidine kinase
A3772_04545	COG2197	response regulator
A3772_04550	COG1131	(ABC) transporter
A3772_04555	COG0842	Transport permease protein
A3772_04555	COG1511	domain protein
A3772_04560	COG0842	Transport permease protein
A3772_04565	COG1695	Transcriptional regulator
A3772_04570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A3772_04575	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
A3772_04580	COG1309	transcriptional regulator
A3772_04585	COG2814	Major facilitator Superfamily
A3772_04590	COG2318	DinB family
A3772_04595	COG2814	Major facilitator Superfamily
A3772_04600	COG1846	Transcriptional regulator
A3772_04605	COG0392	lysyltransferase activity
A3772_04605	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A3772_04610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3772_04615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3772_04620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3772_04625	COG0384	phenazine biosynthesis protein PhzF
A3772_04630	COG0778	Nitroreductase
A3772_04645	COG1090	epimerase
A3772_04650	COG2137	regulation of response to DNA damage stimulus
A3772_04665	COG2814	Major facilitator Superfamily
A3772_04680	COG3103	Sh3 type 3 domain protein
A3772_04685	COG5658	integral membrane protein
A3772_04690	COG0596	Alpha beta hydrolase
A3772_04695	COG0463	Glycosyl transferase, family 2
A3772_04700	COG4485	Bacterial membrane protein, YfhO
A3772_04705	COG1988	membrane-bound metal-dependent
A3772_04710	COG1194	a g-specific adenine glycosylase
A3772_04720	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_04735	COG3557	Belongs to the UPF0374 family
A3772_04740	COG1132	(ABC) transporter
A3772_04745	COG4129	membrane
A3772_04750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A3772_04755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3772_04760	COG0735	belongs to the Fur family
A3772_04875	COG4326	sporulation control protein
A3772_04885	COG5577	PFAM Coat F domain
A3772_04890	COG3340	Belongs to the peptidase S51 family
A3772_04895	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A3772_04900	COG0277	FAD linked oxidase domain protein
A3772_04910	COG0753	catalase activity
A3772_04915	COG1116	anion transmembrane transporter activity
A3772_04920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3772_04925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3772_04930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3772_04940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A3772_04950	COG1476	TRANSCRIPTIONal
A3772_04960	COG3382	B3 4 domain protein
A3772_04965	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A3772_04975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A3772_04980	COG0789	Transcriptional regulator
A3772_04985	COG1664	Polymer-forming cytoskeletal
A3772_04990	COG1664	Polymer-forming cytoskeletal
A3772_04995	COG2766	serine protein kinase
A3772_05000	COG2718	Belongs to the UPF0229 family
A3772_05010	COG1846	Transcriptional regulator
A3772_05015	COG1566	PFAM secretion protein HlyD family protein
A3772_05020	COG2814	Major facilitator Superfamily
A3772_05025	COG0655	NAD(P)H dehydrogenase (quinone) activity
A3772_05040	COG1725	Transcriptional regulator
A3772_05045	COG1131	(ABC) transporter
A3772_05050	COG1131	(ABC) transporter
A3772_05055	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A3772_05060	COG1278	Cold shock
A3772_05070	COG1464	Belongs to the NlpA lipoprotein family
A3772_05075	COG3706	GGDEF domain
A3772_05080	COG1823	symporter activity
A3772_05100	COG5577	PFAM Coat F domain
A3772_05105	COG1525	nuclease
A3772_05105	COG0737	Belongs to the 5'-nucleotidase family
A3772_05105	COG4085	toxin activity
A3772_05110	COG3764	Sortase (surface protein transpeptidase)
A3772_05115	COG0564	pseudouridine synthase activity
A3772_05125	COG0517	IMP dehydrogenase activity
A3772_05130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A3772_05135	COG3153	acetyltransferase
A3772_05135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3772_05140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3772_05145	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A3772_05150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A3772_05155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A3772_05160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A3772_05165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3772_05170	COG2203	Gaf domain
A3772_05170	COG4585	Histidine kinase
A3772_05175	COG2197	response regulator
A3772_05180	COG0431	NADPH-dependent FMN reductase
A3772_05195	COG1388	LysM domain
A3772_05195	COG0791	NLP P60 protein
A3772_05200	COG1959	2 iron, 2 sulfur cluster binding
A3772_05205	COG0668	transmembrane transport
A3772_05210	COG2719	SpoVR family
A3772_05215	COG1785	Belongs to the alkaline phosphatase family
A3772_05220	COG0791	NLP P60 protein
A3772_05220	COG1388	LysM domain
A3772_05225	COG0583	DNA-binding transcription factor activity
A3772_05230	COG0372	Belongs to the citrate synthase family
A3772_05235	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_05240	COG0531	amino acid
A3772_05245	COG0733	neurotransmitter:sodium symporter activity
A3772_05250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3772_05255	COG0456	acetyltransferase
A3772_05270	COG1595	DNA-templated transcription, initiation
A3772_05275	COG0667	Aldo Keto reductase
A3772_05280	COG0204	Acyl-transferase
A3772_05285	COG1253	flavin adenine dinucleotide binding
A3772_05290	COG0789	Transcriptional regulator
A3772_05295	COG0436	Aminotransferase
A3772_05300	COG1253	flavin adenine dinucleotide binding
A3772_05305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3772_05310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3772_05315	COG0584	glycerophosphoryl diester phosphodiesterase
A3772_05325	COG0668	transmembrane transport
A3772_05330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3772_05335	COG0726	polysaccharide deacetylase
A3772_05340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3772_05345	COG1757	Na H antiporter
A3772_05350	COG0589	response to stress
A3772_05360	COG1132	(ABC) transporter
A3772_05365	COG1132	(ABC) transporter
A3772_05370	COG0702	epimerase
A3772_05385	COG0189	ligase activity
A3772_05390	COG0189	ligase activity
A3772_05395	COG4399	Belongs to the UPF0754 family
A3772_05400	COG3679	Belongs to the UPF0342 family
A3772_05405	COG4335	DNA alkylation repair
A3772_05410	COG0561	phosphatase activity
A3772_05415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A3772_05420	COG0475	glutathione-regulated potassium exporter activity
A3772_05425	COG0490	domain, Protein
A3772_05435	COG1024	Enoyl-CoA hydratase
A3772_05445	COG4152	abc transporter atp-binding protein
A3772_05450	COG1668	transmembrane transport
A3772_05455	COG0420	3'-5' exonuclease activity
A3772_05460	COG4717	serine-type aminopeptidase activity
A3772_05465	COG3481	metal-dependent phosphohydrolase, HD sub domain
A3772_05475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A3772_05495	COG1846	Transcriptional regulator
A3772_05500	COG4980	gas vesicle protein
A3772_05515	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A3772_05520	COG0537	adenosine 5'-monophosphoramidase activity
A3772_05525	COG1131	(ABC) transporter
A3772_05530	COG4473	ABC transporter
A3772_05540	COG1473	amidohydrolase
A3772_05545	COG3069	C4-dicarboxylate transmembrane transporter activity
A3772_05555	COG2329	Antibiotic biosynthesis monooxygenase
A3772_05560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3772_05565	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A3772_05580	COG1309	transcriptional regulator
A3772_05585	COG1511	domain protein
A3772_05590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3772_05595	COG4377	Putative membrane peptidase family (DUF2324)
A3772_05605	COG1363	Peptidase, m42
A3772_05610	COG4405	Protein conserved in bacteria
A3772_05615	COG1301	dicarboxylic acid transport
A3772_05625	COG1234	tRNA 3'-trailer cleavage
A3772_05630	COG0095	Lipoate-protein ligase
A3772_05635	COG0702	epimerase
A3772_05640	COG0318	PFAM AMP-dependent synthetase and ligase
A3772_05650	COG0501	Belongs to the peptidase M48B family
A3772_05655	COG1404	Belongs to the peptidase S8 family
A3772_05660	COG0456	acetyltransferase
A3772_05665	COG0604	alcohol dehydrogenase
A3772_05670	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A3772_05675	COG0406	alpha-ribazole phosphatase activity
A3772_05680	COG0183	Belongs to the thiolase family
A3772_05685	COG0318	PFAM AMP-dependent synthetase and ligase
A3772_05690	COG1268	BioY protein
A3772_05695	COG0840	transmembrane signaling receptor activity
A3772_05700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3772_05700	COG0723	plastoquinol--plastocyanin reductase activity
A3772_05705	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_05715	COG4903	ComK protein
A3772_05720	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_05730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3772_05745	COG0398	Pfam SNARE associated Golgi protein
A3772_05750	COG0681	Belongs to the peptidase S26 family
A3772_05755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3772_05760	COG1846	Transcriptional regulator
A3772_05765	COG0738	Major facilitator superfamily
A3772_05770	COG0673	inositol 2-dehydrogenase activity
A3772_05775	COG0561	phosphatase activity
A3772_05780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A3772_05785	COG1609	Transcriptional regulator
A3772_05790	COG3180	Ammonia monooxygenase
A3772_05795	COG0477	Major facilitator Superfamily
A3772_05795	COG2814	Major facilitator Superfamily
A3772_05800	COG4533	DNA binding
A3772_05810	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
A3772_05815	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A3772_05820	COG1074	ATP-dependent DNA helicase activity
A3772_05825	COG0420	3'-5' exonuclease activity
A3772_05830	COG0419	ATPase involved in DNA repair
A3772_05835	COG1403	HNH endonuclease
A3772_05880	COG5337	Spore coat protein CotH
A3772_05885	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3772_05895	COG1404	Belongs to the peptidase S8 family
A3772_05905	COG0367	asparagine synthase
A3772_05910	COG2318	DinB family
A3772_05915	COG1562	ergosterol biosynthetic process
A3772_05920	COG0534	Mate efflux family protein
A3772_05925	COG1917	Cupin 2, conserved barrel domain protein
A3772_05925	COG2207	Transcriptional regulator
A3772_05930	COG1609	Transcriptional regulator
A3772_05935	COG0673	inositol 2-dehydrogenase activity
A3772_05940	COG2318	DinB family
A3772_05945	COG1279	arginine transmembrane transporter activity
A3772_05950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3772_05955	COG1357	PFAM Pentapeptide repeats (8 copies)
A3772_05960	COG2267	carboxylic ester hydrolase activity
A3772_05965	COG0529	Catalyzes the synthesis of activated sulfate
A3772_05970	COG2046	Belongs to the sulfate adenylyltransferase family
A3772_05975	COG0175	sulfate reduction
A3772_05980	COG2045	Belongs to the ComB family
A3772_05985	COG1809	phosphosulfolactate synthase activity
A3772_05990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3772_05995	COG4948	Mandelate Racemase Muconate Lactonizing
A3772_06000	COG2814	Major facilitator Superfamily
A3772_06005	COG0454	-acetyltransferase
A3772_06010	COG2153	protein acetylation
A3772_06015	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A3772_06015	COG0646	methionine synthase
A3772_06020	COG1666	GTP binding
A3772_06025	COG2996	Protein conserved in bacteria
A3772_06045	COG1695	Transcriptional regulator
A3772_06060	COG3227	Zinc metalloprotease (Elastase)
A3772_06065	COG1307	EDD domain protein, DegV family
A3772_06070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3772_06090	COG0561	phosphatase activity
A3772_06095	COG1073	alpha beta
A3772_06100	COG2151	metal-sulfur cluster biosynthetic enzyme
A3772_06110	COG0277	FAD linked oxidase domain protein
A3772_06115	COG2271	Major facilitator Superfamily
A3772_06120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A3772_06135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A3772_06140	COG0505	Belongs to the CarA family
A3772_06145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A3772_06150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A3772_06165	COG2267	carboxylic ester hydrolase activity
A3772_06175	COG1744	ABC transporter substrate-binding protein PnrA-like
A3772_06190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3772_06195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3772_06200	COG5504	Zn-dependent protease
A3772_06205	COG0444	Belongs to the ABC transporter superfamily
A3772_06210	COG4608	Belongs to the ABC transporter superfamily
A3772_06220	COG0601	transmembrane transport
A3772_06225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3772_06235	COG0180	Tryptophanyl-tRNA synthetase
A3772_06240	COG4166	transmembrane transport
A3772_06245	COG0601	transmembrane transport
A3772_06250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3772_06255	COG0444	Belongs to the ABC transporter superfamily
A3772_06260	COG4608	Belongs to the ABC transporter superfamily
A3772_06265	COG2814	Major facilitator Superfamily
A3772_06270	COG0456	acetyltransferase
A3772_06275	COG1393	Belongs to the ArsC family
A3772_06280	COG0861	Integral membrane protein TerC family
A3772_06285	COG4862	establishment of competence for transformation
A3772_06290	COG4469	Competence protein
A3772_06295	COG1164	Oligoendopeptidase f
A3772_06315	COG2346	COG2346, Truncated hemoglobins
A3772_06320	COG0741	lytic transglycosylase activity
A3772_06325	COG4116	CYTH
A3772_06335	COG2357	RelA SpoT domain protein
A3772_06340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3772_06345	COG0564	pseudouridine synthase activity
A3772_06350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A3772_06355	COG0569	domain protein
A3772_06355	COG0475	glutathione-regulated potassium exporter activity
A3772_06360	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A3772_06365	COG0352	thiamine-phosphate diphosphorylase activity
A3772_06370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3772_06375	COG2104	thiamine diphosphate biosynthetic process
A3772_06380	COG2022	thiamine diphosphate biosynthetic process
A3772_06385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3772_06390	COG0351	phosphomethylpyrimidine kinase
A3772_06395	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A3772_06455	COG0210	DNA helicase
A3772_06465	COG2153	protein acetylation
A3772_06470	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A3772_06475	COG2382	esterase
A3772_06480	COG0626	cystathionine gamma-synthase activity
A3772_06485	COG0626	cystathionine gamma-synthase activity
A3772_06490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3772_06495	COG5505	Protein of unknown function (DUF819)
A3772_06530	COG3677	Transposase
A3772_06545	COG5484	DNA packaging
A3772_06550	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A3772_06555	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_06565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3772_06565	COG3711	transcriptional antiterminator
A3772_06570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3772_06570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3772_06570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3772_06575	COG1482	cell wall glycoprotein biosynthetic process
A3772_06585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3772_06595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A3772_06610	COG0109	protoheme IX farnesyltransferase activity
A3772_06620	COG0726	polysaccharide deacetylase
A3772_06640	COG5504	Zn-dependent protease
A3772_06645	COG2205	protein histidine kinase activity
A3772_06655	COG3383	formate dehydrogenase (NAD+) activity
A3772_06660	COG2427	Protein of unknown function (DUF1641)
A3772_06670	COG1051	belongs to the nudix hydrolase family
A3772_06680	COG2124	cytochrome p450
A3772_06685	COG1819	glycosyl
A3772_06695	COG1587	Uroporphyrinogen-III synthase
A3772_06700	COG0390	transport system, permease component
A3772_06705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3772_06710	COG0697	spore germination
A3772_06715	COG4297	protein containing double-stranded beta helix domain
A3772_06725	COG1252	NADH dehydrogenase
A3772_06730	COG1904	glucuronate isomerase
A3772_06735	COG2211	Major facilitator Superfamily
A3772_06740	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A3772_06745	COG1063	alcohol dehydrogenase
A3772_06755	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_06760	COG2271	Major facilitator Superfamily
A3772_06765	COG1609	Transcriptional regulator
A3772_06770	COG0246	Mannitol dehydrogenase
A3772_06775	COG2721	sulfolactate sulfo-lyase activity
A3772_06780	COG0730	response to heat
A3772_06785	COG2318	DinB family
A3772_06790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3772_06795	COG0457	Tetratricopeptide repeat
A3772_06805	COG2350	Protein conserved in bacteria
A3772_06810	COG3409	Peptidoglycan-binding domain 1 protein
A3772_06810	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3772_06810	COG1388	LysM domain
A3772_06820	COG4195	phage-related replication protein
A3772_06825	COG3546	catalase activity
A3772_06830	COG2856	Zn peptidase
A3772_06835	COG1396	sequence-specific DNA binding
A3772_06845	COG1522	sequence-specific DNA binding
A3772_06850	COG1484	DNA-dependent DNA replication
A3772_06875	COG1595	DNA-templated transcription, initiation
A3772_06880	COG5484	DNA packaging
A3772_06880	COG3728	DNA packaging
A3772_06885	COG1783	phage Terminase large subunit
A3772_06890	COG5518	Phage portal protein
A3772_06895	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A3772_06900	COG4653	Phage capsid family
A3772_06950	COG3953	SLT domain
A3772_06950	COG5412	phage tail tape measure protein
A3772_06955	COG1652	LysM domain
A3772_06960	COG4193	domain, Protein
A3772_06970	COG3628	GPW Gp25 family protein
A3772_06975	COG3299	homolog of phage Mu protein gp47
A3772_06980	COG3778	Protein conserved in bacteria
A3772_07020	COG3409	Peptidoglycan-binding domain 1 protein
A3772_07020	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3772_07035	COG0306	phosphate transporter
A3772_07040	COG1392	Phosphate transport regulator
A3772_07045	COG0531	amino acid
A3772_07050	COG0346	lactoylglutathione lyase activity
A3772_07055	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3772_07060	COG0463	Glycosyl transferase, family 2
A3772_07070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3772_07075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3772_07080	COG2362	D-Aminopeptidase
A3772_07085	COG0601	transmembrane transport
A3772_07090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3772_07095	COG0444	Belongs to the ABC transporter superfamily
A3772_07100	COG4166	transmembrane transport
A3772_07105	COG1619	proteins homologs of microcin C7 resistance protein MccF
A3772_07110	COG4948	Mandelate Racemase Muconate Lactonizing
A3772_07115	COG0791	NLP P60 protein
A3772_07120	COG4608	Belongs to the ABC transporter superfamily
A3772_07125	COG2706	6-phosphogluconolactonase activity
A3772_07130	COG1834	amidinotransferase
A3772_07135	COG1607	acyl-coa hydrolase
A3772_07140	COG1017	nitric oxide dioxygenase activity
A3772_07140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A3772_07150	COG2323	membrane
A3772_07155	COG2318	DinB family
A3772_07160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3772_07165	COG2076	Multidrug Resistance protein
A3772_07170	COG2076	Multidrug Resistance protein
A3772_07175	COG0788	formyltetrahydrofolate deformylase activity
A3772_07180	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A3772_07185	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A3772_07190	COG1764	response to oxidative stress
A3772_07195	COG1846	Transcriptional regulator
A3772_07200	COG1764	response to oxidative stress
A3772_07210	COG0590	tRNA wobble adenosine to inosine editing
A3772_07215	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A3772_07220	COG1404	Belongs to the peptidase S8 family
A3772_07225	COG1366	Belongs to the anti-sigma-factor antagonist family
A3772_07230	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A3772_07235	COG1122	ATPase activity
A3772_07240	COG4721	ABC-type cobalt transport system, permease component
A3772_07250	COG0745	RESPONSE REGULATOR receiver
A3772_07255	COG3850	Histidine kinase
A3772_07255	COG5002	protein histidine kinase activity
A3772_07260	COG3212	peptidase
A3772_07265	COG3212	peptidase
A3772_07285	COG2239	Acts as a magnesium transporter
A3772_07290	COG0789	Transcriptional regulator
A3772_07305	COG1846	Transcriptional regulator
A3772_07310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A3772_07315	COG0726	polysaccharide deacetylase
A3772_07320	COG1408	metallophosphoesterase
A3772_07330	COG0463	Glycosyl transferase, family 2
A3772_07335	COG1793	dna ligase
A3772_07335	COG3285	dna ligase
A3772_07340	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A3772_07345	COG5001	Diguanylate cyclase
A3772_07345	COG3300	MHYT domain
A3772_07350	COG0586	Pfam SNARE associated Golgi protein
A3772_07355	COG0861	Integral membrane protein TerC family
A3772_07360	COG1191	sigma factor activity
A3772_07380	COG0501	Belongs to the peptidase M48B family
A3772_07385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3772_07400	COG3594	Acyltransferase
A3772_07405	COG5002	protein histidine kinase activity
A3772_07410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3772_07420	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3772_07425	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
A3772_07430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3772_07435	COG0436	Aminotransferase
A3772_07440	COG1850	ribulose-bisphosphate carboxylase activity
A3772_07445	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
A3772_07450	COG0235	Class ii aldolase
A3772_07455	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
A3772_07460	COG3339	Conserved Protein
A3772_07475	COG3852	Histidine kinase
A3772_07480	COG1846	Transcriptional regulator
A3772_07485	COG1360	Flagellar Motor Protein
A3772_07490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A3772_07495	COG0542	response to heat
A3772_07500	COG3949	Membrane
A3772_07505	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A3772_07510	COG0720	synthase
A3772_07515	COG0602	queuosine metabolic process
A3772_07520	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A3772_07525	COG1733	regulation of RNA biosynthetic process
A3772_07530	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_07535	COG1388	LysM domain
A3772_07535	COG4641	Protein conserved in bacteria
A3772_07540	COG1388	LysM domain
A3772_07545	COG3858	chitin binding
A3772_07550	COG3858	chitin binding
A3772_07560	COG4873	Protein conserved in bacteria
A3772_07575	COG3773	Cell wall hydrolase
A3772_07580	COG2244	polysaccharide biosynthetic process
A3772_07585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_07590	COG2217	Heavy metal translocating P-type atpase
A3772_07600	COG0006	proline dipeptidase activity
A3772_07610	COG1609	Transcriptional regulator
A3772_07615	COG3711	transcriptional antiterminator
A3772_07620	COG1263	PTS System
A3772_07620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3772_07620	COG2190	(PTS) system
A3772_07625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3772_07630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A3772_07640	COG1533	DNA photolyase activity
A3772_07645	COG0456	acetyltransferase
A3772_07650	COG0840	transmembrane signaling receptor activity
A3772_07655	COG2084	Dehydrogenase
A3772_07660	COG2340	Cysteine-rich secretory protein family
A3772_07665	COG0768	penicillin binding
A3772_07670	COG4191	Histidine kinase
A3772_07675	COG0436	Aminotransferase
A3772_07685	COG0784	Response regulator, receiver
A3772_07685	COG0835	chemotaxis
A3772_07695	COG2814	Major facilitator Superfamily
A3772_07700	COG1376	ErfK ybiS ycfS ynhG family protein
A3772_07705	COG1408	metallophosphoesterase
A3772_07710	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_07715	COG3409	Peptidoglycan-binding domain 1 protein
A3772_07720	COG3409	Peptidoglycan-binding domain 1 protein
A3772_07730	COG2200	EAL domain
A3772_07740	COG4703	Protein of unknown function (DUF1797)
A3772_07745	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
A3772_07755	COG0517	IMP dehydrogenase activity
A3772_07760	COG0583	DNA-binding transcription factor activity
A3772_07765	COG0716	FMN binding
A3772_07775	COG0716	FMN binding
A3772_07780	COG2171	N-acyltransferase activity
A3772_07785	COG1473	amidohydrolase
A3772_07795	COG0668	transmembrane transport
A3772_07800	COG0450	alkyl hydroperoxide reductase
A3772_07805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_07820	COG0746	molybdenum cofactor guanylyltransferase activity
A3772_07825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3772_07830	COG0303	'Molybdopterin
A3772_07835	COG1763	Mo-molybdopterin cofactor biosynthetic process
A3772_07840	COG0314	molybdopterin synthase activity
A3772_07845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A3772_07850	COG1132	(ABC) transporter
A3772_07855	COG1132	(ABC) transporter
A3772_07865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A3772_07870	COG1136	(ABC) transporter
A3772_07875	COG0577	efflux transmembrane transporter activity
A3772_07880	COG1349	DNA-binding transcription factor activity
A3772_07885	COG1105	Belongs to the carbohydrate kinase PfkB family
A3772_07890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3772_07890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3772_07890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3772_07895	COG0681	Belongs to the peptidase S26 family
A3772_07905	COG0488	(ABC) transporter
A3772_07910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3772_07915	COG2309	aminopeptidase activity
A3772_07925	COG1077	Cell shape determining protein MreB Mrl
A3772_07930	COG2002	toxin-antitoxin pair type II binding
A3772_07935	COG3852	Histidine kinase
A3772_07940	COG2105	PFAM AIG2 family protein
A3772_07940	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A3772_07945	COG0569	domain protein
A3772_07950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A3772_07955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3772_07965	COG0561	phosphatase activity
A3772_07970	COG0242	peptide deformylase activity
A3772_07980	COG0497	DNA recombination
A3772_07985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A3772_07990	COG0022	dehydrogenase e1 component
A3772_07995	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3772_08000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A3772_08005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_08010	COG1982	Orn Lys Arg decarboxylase major
A3772_08015	COG4476	Belongs to the UPF0223 family
A3772_08020	COG4493	Belongs to the UPF0637 family
A3772_08030	COG0483	inositol monophosphate 1-phosphatase activity
A3772_08040	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3772_08060	COG1595	DNA-templated transcription, initiation
A3772_08090	COG4896	Protein conserved in bacteria
A3772_08100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A3772_08105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A3772_08110	COG2066	Belongs to the glutaminase family
A3772_08115	COG4838	Belongs to the UPF0358 family
A3772_08120	COG0772	Belongs to the SEDS family
A3772_08125	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A3772_08130	COG1612	heme a metabolic process
A3772_08135	COG0109	protoheme IX farnesyltransferase activity
A3772_08140	COG2010	Cytochrome c
A3772_08140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A3772_08145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A3772_08150	COG1845	cytochrome c oxidase, subunit III
A3772_08155	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A3772_08160	COG3336	cytochrome c oxidase
A3772_08170	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A3772_08175	COG2340	Cysteine-rich secretory protein family
A3772_08190	COG3679	Belongs to the UPF0342 family
A3772_08195	COG4471	UPF0298 protein
A3772_08200	COG0742	ribosomal rna small subunit methyltransferase
A3772_08205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A3772_08210	COG3314	Sporulation integral membrane protein YlbJ
A3772_08215	COG1752	Esterase of the alpha-beta hydrolase superfamily
A3772_08220	COG3480	Lon protease (S16) C-terminal proteolytic domain
A3772_08225	COG1323	Belongs to the UPF0348 family
A3772_08235	COG1399	metal-binding, possibly nucleic acid-binding protein
A3772_08240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A3772_08250	COG0454	-acetyltransferase
A3772_08255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3772_08260	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
A3772_08265	COG2001	Belongs to the MraZ family
A3772_08270	COG0275	rRNA processing
A3772_08275	COG4839	cell division protein FtsL
A3772_08290	COG0768	penicillin binding
A3772_08300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A3772_08310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3772_08315	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A3772_08320	COG0772	Belongs to the SEDS family
A3772_08325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A3772_08330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A3772_08335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A3772_08340	COG3879	Bacterial protein of unknown function (DUF881)
A3772_08345	COG3879	Bacterial protein of unknown function (DUF881)
A3772_08350	COG3856	small basic protein
A3772_08355	COG0849	cell division
A3772_08360	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3772_08365	COG1404	Belongs to the peptidase S8 family
A3772_08365	COG4412	M6 family metalloprotease domain protein
A3772_08375	COG1191	sigma factor activity
A3772_08380	COG1191	sigma factor activity
A3772_08385	COG1119	ATPase activity
A3772_08390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3772_08395	COG1873	PFAM PRC-barrel domain
A3772_08405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A3772_08410	COG1799	cell septum assembly
A3772_08415	COG0762	integral membrane protein
A3772_08420	COG2302	S4 RNA-binding domain
A3772_08425	COG3599	regulation of cell shape
A3772_08430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A3772_08435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A3772_08440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A3772_08445	COG0564	pseudouridine synthase activity
A3772_08450	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A3772_08455	COG2233	PERMEase
A3772_08460	COG0540	Belongs to the ATCase OTCase family
A3772_08465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3772_08470	COG0505	Belongs to the CarA family
A3772_08475	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A3772_08480	COG0543	2 iron, 2 sulfur cluster binding
A3772_08485	COG0167	dihydroorotate dehydrogenase activity
A3772_08490	COG0284	orotidine-5'-phosphate decarboxylase activity
A3772_08495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A3772_08500	COG0175	sulfate reduction
A3772_08505	COG0306	phosphate transporter
A3772_08510	COG2046	Belongs to the sulfate adenylyltransferase family
A3772_08515	COG0529	Catalyzes the synthesis of activated sulfate
A3772_08520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A3772_08525	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
A3772_08530	COG1648	precorrin-2 dehydrogenase activity
A3772_08540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A3772_08545	COG1561	YicC-like family, N-terminal region
A3772_08550	COG2052	Domain of unknown function (DUF370)
A3772_08555	COG0194	GDP metabolic process
A3772_08560	COG1758	RNA polymerase activity
A3772_08565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A3772_08570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A3772_08575	COG0242	peptide deformylase activity
A3772_08580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A3772_08585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3772_08585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3772_08590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A3772_08595	COG0631	protein serine/threonine phosphatase activity
A3772_08600	COG0515	serine threonine protein kinase
A3772_08600	COG2815	serine threonine protein kinase
A3772_08605	COG1162	GTPase activity
A3772_08610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A3772_08615	COG1564	THIamine pyrophosphokinase
A3772_08625	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A3772_08630	COG1302	Protein conserved in bacteria
A3772_08635	COG1461	Dihydroxyacetone kinase
A3772_08640	COG1760	l-serine dehydratase
A3772_08645	COG1760	l-serine dehydratase
A3772_08650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A3772_08655	COG1349	DNA-binding transcription factor activity
A3772_08655	COG2050	protein possibly involved in aromatic compounds catabolism
A3772_08660	COG0416	fatty acid biosynthetic process
A3772_08665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A3772_08670	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_08675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3772_08680	COG0571	ribonuclease III activity
A3772_08685	COG1196	nuclear chromosome segregation
A3772_08690	COG0552	protein localization to endoplasmic reticulum
A3772_08700	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
A3772_08705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3772_08710	COG0228	four-way junction DNA binding
A3772_08715	COG1837	Belongs to the UPF0109 family
A3772_08725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A3772_08730	COG0336	Belongs to the RNA methyltransferase TrmD family
A3772_08735	COG0335	large ribosomal subunit rRNA binding
A3772_08740	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A3772_08745	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A3772_08755	COG2257	FlhB HrpN YscU SpaS Family
A3772_08760	COG0045	succinate-CoA ligase (ADP-forming) activity
A3772_08765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A3772_08770	COG0758	DNA mediated transformation
A3772_08775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3772_08780	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A3772_08785	COG4974	Belongs to the 'phage' integrase family
A3772_08790	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A3772_08795	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A3772_08800	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A3772_08805	COG1815	bacterial-type flagellum-dependent cell motility
A3772_08810	COG1558	bacterial-type flagellum-dependent cell motility
A3772_08815	COG1677	Flagellar hook-basal body complex protein FliE
A3772_08820	COG1766	The M ring may be actively involved in energy transduction
A3772_08825	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A3772_08830	COG1317	bacterial-type flagellum organization
A3772_08835	COG1157	protein secretion by the type III secretion system
A3772_08840	COG2882	bacterial-type flagellum organization
A3772_08845	COG3334	PFAM MgtE intracellular
A3772_08850	COG3144	bacterial-type flagellum assembly
A3772_08855	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A3772_08860	COG4786	Flagellar basal body rod
A3772_08865	COG1582	Flagellar protein (FlbD)
A3772_08870	COG1580	Controls the rotational direction of flagella during chemotaxis
A3772_08875	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A3772_08880	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A3772_08880	COG1776	CheC inhibitor of MCP methylation
A3772_08885	COG2201	protein-glutamate methylesterase activity
A3772_08890	COG3190	flagellar
A3772_08895	COG1338	Plays a role in the flagellum-specific transport system
A3772_08900	COG1987	bacterial-type flagellum assembly
A3772_08905	COG1684	flagellar biosynthetic protein fliR
A3772_08910	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A3772_08915	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A3772_08920	COG1419	protein localization to endoplasmic reticulum
A3772_08925	COG0455	bacterial-type flagellum organization
A3772_08930	COG2201	protein-glutamate methylesterase activity
A3772_08935	COG2198	Histidine kinase
A3772_08935	COG0643	Histidine kinase
A3772_08940	COG0835	chemotaxis
A3772_08945	COG1776	CheC inhibitor of MCP methylation
A3772_08950	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
A3772_08955	COG1191	sigma factor activity
A3772_08965	COG0052	Belongs to the universal ribosomal protein uS2 family
A3772_08970	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A3772_08975	COG0528	UMP kinase activity
A3772_08980	COG0233	cytoplasmic translational termination
A3772_08985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3772_08990	COG4589	Belongs to the CDS family
A3772_08995	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A3772_09000	COG0750	zinc metalloprotease
A3772_09005	COG0442	prolyl-tRNA aminoacylation
A3772_09010	COG2176	DNA-directed DNA polymerase activity
A3772_09015	COG0779	Required for maturation of 30S ribosomal subunits
A3772_09020	COG0195	Participates in both transcription termination and antitermination
A3772_09025	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A3772_09030	COG1358	cellular component organization or biogenesis
A3772_09035	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A3772_09040	COG1550	Protein conserved in bacteria
A3772_09045	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A3772_09050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A3772_09055	COG0196	riboflavin kinase activity
A3772_09060	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A3772_09065	COG1185	polyribonucleotide nucleotidyltransferase activity
A3772_09070	COG0726	polysaccharide deacetylase
A3772_09075	COG0612	Peptidase, M16
A3772_09080	COG1873	PFAM PRC-barrel domain
A3772_09090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3772_09095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A3772_09100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A3772_09105	COG0527	aspartate kinase activity
A3772_09110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3772_09115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3772_09120	COG0740	serine-type endopeptidase activity
A3772_09130	COG1674	ftsk spoiiie
A3772_09130	COG4980	gas vesicle protein
A3772_09135	COG2188	Transcriptional regulator
A3772_09140	COG2814	Major facilitator Superfamily
A3772_09145	COG0612	Peptidase, M16
A3772_09150	COG0612	Peptidase, M16
A3772_09155	COG0300	oxidoreductase activity
A3772_09170	COG1426	Protein conserved in bacteria
A3772_09175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3772_09180	COG1546	Belongs to the CinA family
A3772_09180	COG1058	Belongs to the CinA family
A3772_09185	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A3772_09190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3772_09195	COG1418	mRNA catabolic process
A3772_09200	COG1692	metallophosphoesterase
A3772_09205	COG2359	stage V sporulation protein S
A3772_09210	COG1063	alcohol dehydrogenase
A3772_09215	COG0156	8-amino-7-oxononanoate synthase activity
A3772_09220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3772_09225	COG4550	Control of competence regulator ComK, YlbF/YmcA
A3772_09235	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A3772_09240	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A3772_09260	COG3226	Transcriptional regulator
A3772_09265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3772_09275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A3772_09280	COG3321	synthase
A3772_09285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A3772_09285	COG2070	2-Nitropropane dioxygenase
A3772_09290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3772_09295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3772_09300	COG3425	synthase
A3772_09305	COG1024	Enoyl-CoA hydratase
A3772_09310	COG1024	Enoyl-CoA hydratase
A3772_09315	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_09315	COG0318	PFAM AMP-dependent synthetase and ligase
A3772_09315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_09315	COG0300	oxidoreductase activity
A3772_09315	COG3321	synthase
A3772_09320	COG3321	synthase
A3772_09320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3772_09320	COG0300	oxidoreductase activity
A3772_09320	COG4221	oxidoreductase activity
A3772_09325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_09325	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_09325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3772_09325	COG3321	synthase
A3772_09325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3772_09330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_09330	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_09330	COG3321	synthase
A3772_09330	COG4221	oxidoreductase activity
A3772_09335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3772_09335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3772_09335	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A3772_09335	COG3321	synthase
A3772_09340	COG2124	cytochrome p450
A3772_09350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3772_09355	COG1404	Belongs to the peptidase S8 family
A3772_09365	COG4195	phage-related replication protein
A3772_09370	COG1764	response to oxidative stress
A3772_09375	COG2076	Multidrug Resistance protein
A3772_09380	COG2076	Multidrug Resistance protein
A3772_09395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A3772_09400	COG1923	regulation of RNA biosynthetic process
A3772_09415	COG1780	Probably involved in ribonucleotide reductase function
A3772_09420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3772_09425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3772_09430	COG4112	unkown
A3772_09435	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3772_09440	COG0464	growth
A3772_09450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3772_09455	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A3772_09460	COG0789	Transcriptional regulator
A3772_09465	COG0174	glutamine synthetase
A3772_09485	COG4282	regulation of fungal-type cell wall biogenesis
A3772_09495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3772_09520	COG0135	phosphoribosylanthranilate isomerase activity
A3772_09525	COG2211	Major facilitator Superfamily
A3772_09530	COG3507	Belongs to the glycosyl hydrolase 43 family
A3772_09535	COG1940	carbohydrate kinase activity
A3772_09540	COG2115	Belongs to the xylose isomerase family
A3772_09545	COG1070	Carbohydrate kinase
A3772_09550	COG1525	nuclease
A3772_09555	COG2814	Major facilitator Superfamily
A3772_09560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A3772_09570	COG0756	dUTP diphosphatase activity
A3772_09580	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A3772_09605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A3772_09620	COG3832	glyoxalase III activity
A3772_09635	COG0697	spore germination
A3772_09640	COG0531	amino acid
A3772_09670	COG4195	phage-related replication protein
A3772_09680	COG0346	lactoylglutathione lyase activity
A3772_09690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3772_09695	COG1388	LysM domain
A3772_09700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A3772_09705	COG4224	UPF0291 protein
A3772_09710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A3772_09720	COG3763	UPF0154 protein
A3772_09730	COG0785	Cytochrome C biogenesis protein
A3772_09735	COG2201	protein-glutamate methylesterase activity
A3772_09740	COG4846	Membrane protein involved in cytochrome C biogenesis
A3772_09750	COG0071	Belongs to the small heat shock protein (HSP20) family
A3772_09765	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A3772_09770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_09790	COG0824	Thioesterase
A3772_09800	COG4841	protein insertion into membrane
A3772_09805	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A3772_09810	COG1832	CoA-binding protein
A3772_09815	COG0187	DNA topoisomerase II activity
A3772_09820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A3772_09835	COG1115	amino acid carrier protein
A3772_09840	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
A3772_09850	COG5520	Belongs to the glycosyl hydrolase 30 family
A3772_09855	COG3507	Belongs to the glycosyl hydrolase 43 family
A3772_09865	COG2246	polysaccharide biosynthetic process
A3772_09870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3772_09875	COG0586	Pfam SNARE associated Golgi protein
A3772_09880	COG2404	hydrolase activity, acting on ester bonds
A3772_09885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3772_09890	COG1024	Enoyl-CoA hydratase
A3772_09895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A3772_09900	COG0511	ligase activity, forming carbon-carbon bonds
A3772_09905	COG0439	Biotin carboxylase
A3772_09910	COG0318	PFAM AMP-dependent synthetase and ligase
A3772_09915	COG1960	acyl-CoA dehydrogenase activity
A3772_09930	COG1649	PFAM Uncharacterised BCR, COG1649
A3772_09940	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A3772_09940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_09945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_09950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_09955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_09960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_09965	COG2027	D-alanyl-D-alanine carboxypeptidase
A3772_09970	COG2017	converts alpha-aldose to the beta-anomer
A3772_09975	COG0534	Mate efflux family protein
A3772_09990	COG0582	viral genome integration into host DNA
A3772_09995	COG0166	Belongs to the GPI family
A3772_10000	COG0405	Gamma-glutamyltransferase
A3772_10005	COG0583	DNA-binding transcription factor activity
A3772_10010	COG0604	alcohol dehydrogenase
A3772_10015	COG0493	'glutamate synthase
A3772_10020	COG0067	glutamate synthase
A3772_10020	COG0070	glutamate synthase
A3772_10020	COG0069	glutamate synthase activity
A3772_10025	COG0583	DNA-binding transcription factor activity
A3772_10030	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A3772_10035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3772_10045	COG0300	oxidoreductase activity
A3772_10050	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
A3772_10060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3772_10065	COG2814	Major facilitator Superfamily
A3772_10070	COG1070	Carbohydrate kinase
A3772_10075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A3772_10080	COG0243	molybdopterin cofactor binding
A3772_10105	COG0840	transmembrane signaling receptor activity
A3772_10105	COG5278	phosphoserine phosphatase activity
A3772_10110	COG2368	4-hydroxyphenylacetate
A3772_10115	COG4305	rare lipoprotein A
A3772_10120	COG3619	membrane
A3772_10125	COG3866	Pectate lyase
A3772_10130	COG2135	peptidase activity
A3772_10140	COG2140	Oxalate decarboxylase
A3772_10150	COG0456	acetyltransferase
A3772_10165	COG2720	vancomycin resistance protein
A3772_10175	COG3655	Transcriptional regulator
A3772_10180	COG3739	integral membrane protein
A3772_10185	COG0583	DNA-binding transcription factor activity
A3772_10190	COG0697	spore germination
A3772_10200	COG0693	protein deglycase activity
A3772_10205	COG2367	Beta-lactamase
A3772_10225	COG3848	Pyruvate phosphate dikinase
A3772_10225	COG0574	Belongs to the PEP-utilizing enzyme family
A3772_10230	COG0726	polysaccharide deacetylase
A3772_10235	COG2314	TM2 domain
A3772_10240	COG1396	sequence-specific DNA binding
A3772_10255	COG2135	peptidase activity
A3772_10260	COG1793	dna ligase
A3772_10290	COG0457	Tetratricopeptide repeat
A3772_10300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A3772_10305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A3772_10320	COG5290	Psort location Cytoplasmic, score
A3772_10340	COG5444	nuclease activity
A3772_10345	COG4282	regulation of fungal-type cell wall biogenesis
A3772_10350	COG1231	oxidoreductase activity
A3772_10355	COG5434	Belongs to the glycosyl hydrolase 28 family
A3772_10360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3772_10365	COG0662	Cupin 2, conserved barrel domain protein
A3772_10365	COG2207	Transcriptional regulator
A3772_10370	COG0456	acetyltransferase
A3772_10375	COG1309	transcriptional regulator
A3772_10380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3772_10385	COG3708	Transcriptional regulator
A3772_10390	COG2378	regulation of single-species biofilm formation
A3772_10400	COG0640	Transcriptional regulator
A3772_10405	COG0741	lytic transglycosylase activity
A3772_10410	COG2322	membrane
A3772_10425	COG1619	proteins homologs of microcin C7 resistance protein MccF
A3772_10430	COG3239	Fatty acid desaturase
A3772_10435	COG4585	Histidine kinase
A3772_10440	COG2197	response regulator
A3772_10445	COG3584	3D domain protein
A3772_10445	COG1388	LysM domain
A3772_10450	COG0514	ATP-dependent DNA helicase (RecQ)
A3772_10465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A3772_10470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A3772_10485	COG0071	Belongs to the small heat shock protein (HSP20) family
A3772_10510	COG1012	belongs to the aldehyde dehydrogenase family
A3772_10515	COG1657	PFAM Prenyltransferase squalene oxidase
A3772_10520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A3772_10525	COG0733	neurotransmitter:sodium symporter activity
A3772_10530	COG0385	Bile acid
A3772_10535	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3772_10540	COG0567	Dehydrogenase, E1 component
A3772_10545	COG4548	von Willebrand factor, type A
A3772_10550	COG0714	Associated with various cellular activities
A3772_10555	COG2032	superoxide dismutase activity
A3772_10560	COG0791	NLP P60 protein
A3772_10560	COG1388	LysM domain
A3772_10565	COG1819	glycosyl
A3772_10570	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A3772_10575	COG0534	Mate efflux family protein
A3772_10580	COG1366	Belongs to the anti-sigma-factor antagonist family
A3772_10585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A3772_10590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A3772_10600	COG2962	Rard protein
A3772_10615	COG2610	gluconate transmembrane transporter activity
A3772_10620	COG1942	4-Oxalocrotonate Tautomerase
A3772_10625	COG1733	regulation of RNA biosynthetic process
A3772_10630	COG0778	Nitroreductase
A3772_10635	COG0400	carboxylic ester hydrolase activity
A3772_10640	COG0346	lactoylglutathione lyase activity
A3772_10650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3772_10655	COG0793	Belongs to the peptidase S41A family
A3772_10655	COG3409	Peptidoglycan-binding domain 1 protein
A3772_10660	COG2226	methyltransferase
A3772_10670	COG1876	peptidase activity
A3772_10675	COG0813	purine-nucleoside phosphorylase activity
A3772_10690	COG0671	phosphoesterase, PA-phosphatase related
A3772_10715	COG4479	Belongs to the UPF0346 family
A3772_10725	COG1509	lysine 2,3-aminomutase activity
A3772_10730	COG0456	acetyltransferase
A3772_10735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3772_10740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A3772_10745	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A3772_10750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3772_10765	COG0456	acetyltransferase
A3772_10770	COG0463	Glycosyl transferase, family 2
A3772_10785	COG4641	Protein conserved in bacteria
A3772_10790	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
A3772_10795	COG1086	Polysaccharide biosynthesis protein
A3772_10805	COG3331	DNA recombination
A3772_10855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A3772_10890	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A3772_10895	COG0756	dUTP diphosphatase activity
A3772_10900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_10930	COG1372	Participates in initiation and elongation during chromosome replication
A3772_10930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3772_10935	COG1780	Probably involved in ribonucleotide reductase function
A3772_11025	COG0270	DNA (cytosine-5-)-methyltransferase activity
A3772_11035	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
A3772_11040	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A3772_11065	COG3584	3D domain protein
A3772_11070	COG0587	DNA-directed DNA polymerase activity
A3772_11075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A3772_11080	COG0358	DNA primase activity
A3772_11085	COG0305	Participates in initiation and elongation during chromosome replication
A3772_11095	COG2887	Belongs to the helicase family. UvrD subfamily
A3772_11125	COG5434	Belongs to the glycosyl hydrolase 28 family
A3772_11125	COG3420	alginic acid biosynthetic process
A3772_11130	COG4195	phage-related replication protein
A3772_11145	COG2135	peptidase activity
A3772_11150	COG1793	dna ligase
A3772_11205	COG4474	Belongs to the UPF0398 family
A3772_11215	COG1388	LysM domain
A3772_11235	COG3646	Phage regulatory protein
A3772_11235	COG3645	SOS response
A3772_11290	COG3655	Transcriptional regulator
A3772_11305	COG0582	viral genome integration into host DNA
A3772_11380	COG3655	Transcriptional regulator
A3772_11415	COG1395	domain, Protein
A3772_11430	COG0776	regulation of translation
A3772_11460	COG4373	Mu-like prophage FluMu protein gp28
A3772_11560	COG0582	viral genome integration into host DNA
A3772_11590	COG0739	heme binding
A3772_11590	COG0741	lytic transglycosylase activity
A3772_11590	COG1196	nuclear chromosome segregation
A3772_11600	COG2433	Pfam Transposase IS66
A3772_11610	COG5434	Belongs to the glycosyl hydrolase 28 family
A3772_11610	COG4632	Exopolysaccharide biosynthesis protein
A3772_11625	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3772_11640	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A3772_11645	COG0463	Glycosyl transferase, family 2
A3772_11650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_11655	COG3271	cysteine-type peptidase activity
A3772_11655	COG2274	protein secretion by the type I secretion system
A3772_11670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A3772_11700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3772_11715	COG5444	nuclease activity
A3772_11720	COG4282	regulation of fungal-type cell wall biogenesis
A3772_11730	COG1525	nuclease
A3772_11740	COG2746	aminoglycoside 3-N-acetyltransferase activity
A3772_11765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A3772_11770	COG1086	Polysaccharide biosynthesis protein
A3772_11775	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3772_11780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3772_11785	COG1846	Transcriptional regulator
A3772_11790	COG0534	Mate efflux family protein
A3772_11800	COG4698	Protein conserved in bacteria
A3772_11805	COG2755	lipolytic protein G-D-S-L family
A3772_11810	COG1999	signal sequence binding
A3772_11825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A3772_11830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A3772_11835	COG1272	protein, Hemolysin III
A3772_11840	COG0204	Acyl-transferase
A3772_11845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A3772_11850	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A3772_11855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A3772_11865	COG2521	methyltransferase
A3772_11865	COG2136	Putative SAM-dependent methyltransferase
A3772_11875	COG0129	dihydroxy-acid dehydratase activity
A3772_11880	COG1413	lyase activity
A3772_11885	COG1418	mRNA catabolic process
A3772_11890	COG0386	Belongs to the glutathione peroxidase family
A3772_11895	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
A3772_11900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A3772_11905	COG1278	Cold shock
A3772_11925	COG0328	RNA-DNA hybrid ribonuclease activity
A3772_11930	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A3772_11935	COG0328	RNA-DNA hybrid ribonuclease activity
A3772_11945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A3772_11965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A3772_11970	COG1755	Isoprenylcysteine carboxyl methyltransferase
A3772_11975	COG3424	synthase
A3772_11980	COG2233	PERMEase
A3772_11985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3772_11990	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A3772_12000	COG0800	Aldolase
A3772_12005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3772_12010	COG1609	Transcriptional regulator
A3772_12015	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
A3772_12020	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_12025	COG1199	ATP-dependent helicase activity
A3772_12035	COG0116	Belongs to the methyltransferase superfamily
A3772_12050	COG4474	Belongs to the UPF0398 family
A3772_12060	COG3359	exonuclease
A3772_12065	COG1111	helicase
A3772_12065	COG1205	dead DEAH box helicase
A3772_12070	COG2190	(PTS) system
A3772_12075	COG0071	Belongs to the small heat shock protein (HSP20) family
A3772_12110	COG3331	DNA recombination
A3772_12115	COG4499	WXG100 protein secretion system (Wss), protein YukC
A3772_12115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3772_12125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A3772_12130	COG3935	DnaD domain protein
A3772_12135	COG0017	Asparaginyl-tRNA synthetase
A3772_12140	COG0436	Aminotransferase
A3772_12145	COG5353	protein conserved in bacteria
A3772_12155	COG1199	ATP-dependent helicase activity
A3772_12155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A3772_12160	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A3772_12165	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A3772_12170	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A3772_12175	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A3772_12175	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A3772_12180	COG0617	tRNA 3'-terminal CCA addition
A3772_12185	COG0438	transferase activity, transferring glycosyl groups
A3772_12190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A3772_12195	COG1803	Methylglyoxal synthase
A3772_12200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A3772_12205	COG1694	Mazg nucleotide pyrophosphohydrolase
A3772_12210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3772_12220	COG4347	Protein of unknown function (DUF1405)
A3772_12225	COG2010	Cytochrome c
A3772_12225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A3772_12230	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A3772_12235	COG0723	plastoquinol--plastocyanin reductase activity
A3772_12245	COG5582	Belongs to the UPF0302 family
A3772_12250	COG0457	Tetratricopeptide repeat
A3772_12255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A3772_12260	COG0287	Prephenate dehydrogenase
A3772_12265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3772_12270	COG0159	tryptophan synthase activity
A3772_12275	COG0133	tryptophan synthase activity
A3772_12280	COG0135	phosphoribosylanthranilate isomerase activity
A3772_12290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A3772_12295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A3772_12300	COG4401	Chorismate mutase type I
A3772_12305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A3772_12310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A3772_12315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A3772_12325	COG0105	UTP biosynthetic process
A3772_12330	COG0142	geranyltranstransferase activity
A3772_12335	COG2226	methyltransferase
A3772_12340	COG0142	geranyltranstransferase activity
A3772_12350	COG0302	gtp cyclohydrolase
A3772_12355	COG0776	regulation of translation
A3772_12360	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A3772_12375	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A3772_12380	COG1160	GTP binding
A3772_12405	COG1304	FMN binding
A3772_12410	COG0539	negative regulation of cytoplasmic translation
A3772_12415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A3772_12425	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
A3772_12430	COG2959	enzyme of heme biosynthesis
A3772_12435	COG3773	Cell wall hydrolase
A3772_12435	COG3409	Peptidoglycan-binding domain 1 protein
A3772_12440	COG2339	peptidase activity
A3772_12445	COG0492	ferredoxin-NADP+ reductase activity
A3772_12455	COG4862	establishment of competence for transformation
A3772_12460	COG1408	metallophosphoesterase
A3772_12470	COG1388	LysM domain
A3772_12475	COG1266	CAAX protease self-immunity
A3772_12480	COG0514	ATP-dependent DNA helicase (RecQ)
A3772_12485	COG4955	Helix-turn-helix domain
A3772_12490	COG1141	Ferredoxin
A3772_12495	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A3772_12500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A3772_12505	COG0710	3-dehydroquinate dehydratase activity
A3772_12515	COG1595	DNA-templated transcription, initiation
A3772_12520	COG5002	protein histidine kinase activity
A3772_12525	COG0745	RESPONSE REGULATOR receiver
A3772_12530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A3772_12535	COG1333	cytochrome c biogenesis protein
A3772_12540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_12545	COG1187	pseudouridine synthase activity
A3772_12550	COG0700	Nucleoside recognition
A3772_12555	COG2715	membrane protein required for spore maturation
A3772_12560	COG1686	Belongs to the peptidase S11 family
A3772_12570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A3772_12575	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A3772_12580	COG1547	Domain of unknown function (DUF309)
A3772_12585	COG0456	acetyltransferase
A3772_12590	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A3772_12595	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A3772_12595	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A3772_12600	COG0307	riboflavin synthase, alpha
A3772_12605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A3772_12605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A3772_12615	COG0681	Belongs to the peptidase S26 family
A3772_12620	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
A3772_12645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A3772_12650	COG4086	secreted protein
A3772_12655	COG0019	diaminopimelate decarboxylase activity
A3772_12660	COG0697	spore germination
A3772_12675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3772_12695	COG1191	sigma factor activity
A3772_12700	COG2172	sigma factor antagonist activity
A3772_12705	COG1366	Belongs to the anti-sigma-factor antagonist family
A3772_12710	COG1686	Belongs to the peptidase S11 family
A3772_12715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3772_12720	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A3772_12725	COG4974	Belongs to the 'phage' integrase family
A3772_12735	COG0735	belongs to the Fur family
A3772_12740	COG1300	Membrane
A3772_12750	COG0281	malic enzyme
A3772_12755	COG1757	Na H antiporter
A3772_12760	COG1027	Aspartate ammonia-lyase
A3772_12765	COG0252	asparaginase activity
A3772_12770	COG1396	sequence-specific DNA binding
A3772_12775	COG1379	DNA repair
A3772_12780	COG0494	nUDIX hydrolase
A3772_12790	COG0667	Aldo Keto reductase
A3772_12800	COG1073	alpha beta
A3772_12810	COG4918	Iron-sulphur cluster biosynthesis
A3772_12815	COG0456	acetyltransferase
A3772_12815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A3772_12820	COG2329	Antibiotic biosynthesis monooxygenase
A3772_12825	COG0456	acetyltransferase
A3772_12835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A3772_12845	COG2211	Major facilitator Superfamily
A3772_12855	COG0346	lactoylglutathione lyase activity
A3772_12860	COG1072	(Pantothenic acid kinase))
A3772_12865	COG3048	D-serine ammonia-lyase activity
A3772_12870	COG0300	oxidoreductase activity
A3772_12875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3772_12880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3772_12885	COG4187	Peptidase family M20/M25/M40
A3772_12890	COG1902	pentaerythritol trinitrate reductase activity
A3772_12895	COG0596	Alpha beta hydrolase
A3772_12900	COG1234	tRNA 3'-trailer cleavage
A3772_12905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A3772_12910	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A3772_12915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A3772_12925	COG0706	membrane insertase activity
A3772_12930	COG3361	conserved protein (COG2071)
A3772_12935	COG2195	Cleaves the N-terminal amino acid of tripeptides
A3772_12940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3772_12945	COG0346	lactoylglutathione lyase activity
A3772_12955	COG1376	ErfK ybiS ycfS ynhG family protein
A3772_12960	COG4129	membrane
A3772_12965	COG1126	abc transporter atp-binding protein
A3772_12970	COG0765	amino acid transport
A3772_12975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3772_12985	COG1597	lipid kinase activity
A3772_12990	COG2814	Major facilitator Superfamily
A3772_12995	COG0789	Transcriptional regulator
A3772_12995	COG4978	Transcriptional regulator
A3772_13000	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3772_13005	COG0022	dehydrogenase e1 component
A3772_13010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A3772_13015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A3772_13020	COG3426	butyrate kinase activity
A3772_13025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3772_13030	COG0280	phosphate acetyltransferase
A3772_13035	COG3829	transcription factor binding
A3772_13035	COG3290	protein histidine kinase activity
A3772_13045	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A3772_13050	COG2079	MmgE PrpD family protein
A3772_13055	COG0372	Belongs to the citrate synthase family
A3772_13060	COG1960	acyl-CoA dehydrogenase activity
A3772_13065	COG1250	3-hydroxyacyl-CoA dehydrogenase
A3772_13070	COG0183	Belongs to the thiolase family
A3772_13075	COG0584	glycerophosphoryl diester phosphodiesterase
A3772_13080	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3772_13095	COG1902	pentaerythritol trinitrate reductase activity
A3772_13105	COG0745	RESPONSE REGULATOR receiver
A3772_13115	COG0750	zinc metalloprotease
A3772_13120	COG0497	DNA recombination
A3772_13125	COG1438	arginine binding
A3772_13130	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A3772_13135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A3772_13140	COG0142	geranyltranstransferase activity
A3772_13145	COG1722	exodeoxyribonuclease VII activity
A3772_13150	COG1570	exodeoxyribonuclease VII activity
A3772_13155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A3772_13160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3772_13165	COG1302	Protein conserved in bacteria
A3772_13170	COG0439	Biotin carboxylase
A3772_13175	COG0511	ligase activity, forming carbon-carbon bonds
A3772_13215	COG3854	ATPases associated with a variety of cellular activities
A3772_13225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A3772_13230	COG0006	proline dipeptidase activity
A3772_13235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A3772_13245	COG3872	metal-dependent enzyme
A3772_13255	COG1752	Esterase of the alpha-beta hydrolase superfamily
A3772_13260	COG1321	iron dependent repressor
A3772_13265	COG0095	Lipoate-protein ligase
A3772_13270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A3772_13275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3772_13280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3772_13285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A3772_13290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A3772_13305	COG1396	sequence-specific DNA binding
A3772_13315	COG0681	Belongs to the peptidase S26 family
A3772_13340	COG4940	Competence protein ComGF
A3772_13350	COG4970	Tfp pilus assembly protein FimT
A3772_13355	COG4537	Required for transformation and DNA binding
A3772_13360	COG1459	type II secretion system
A3772_13365	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A3772_13375	COG0598	Magnesium transport protein CorA
A3772_13380	COG1253	flavin adenine dinucleotide binding
A3772_13385	COG1366	Belongs to the anti-sigma-factor antagonist family
A3772_13395	COG1393	Belongs to the ArsC family
A3772_13405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3772_13415	COG0011	TIGRFAM Protein of
A3772_13425	COG2866	Carboxypeptidase
A3772_13430	COG1368	sulfuric ester hydrolase activity
A3772_13435	COG1940	carbohydrate kinase activity
A3772_13440	COG4483	Protein conserved in bacteria
A3772_13445	COG0457	Tetratricopeptide repeat
A3772_13445	COG0705	Rhomboid family
A3772_13455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A3772_13460	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A3772_13465	COG0438	transferase activity, transferring glycosyl groups
A3772_13480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A3772_13485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3772_13490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3772_13495	COG0581	inorganic phosphate transmembrane transporter activity
A3772_13500	COG0573	inorganic phosphate transmembrane transporter activity
A3772_13505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A3772_13515	COG0477	Major facilitator Superfamily
A3772_13520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A3772_13525	COG2839	Protein conserved in bacteria
A3772_13530	COG5521	maltodextrose utilization protein MalA
A3772_13540	COG1388	LysM domain
A3772_13545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A3772_13550	COG4709	membrane
A3772_13555	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
A3772_13560	COG0735	belongs to the Fur family
A3772_13565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3772_13575	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A3772_13580	COG0513	Belongs to the DEAD box helicase family
A3772_13590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A3772_13595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A3772_13600	COG2384	SAM-dependent methyltransferase
A3772_13605	COG2010	Cytochrome c
A3772_13610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A3772_13615	COG0358	DNA primase activity
A3772_13620	COG1671	Belongs to the UPF0178 family
A3772_13625	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
A3772_13630	COG0517	IMP dehydrogenase activity
A3772_13635	COG0751	glycine-tRNA ligase activity
A3772_13640	COG0752	glycyl-tRNA synthetase alpha subunit
A3772_13645	COG1381	Involved in DNA repair and RecF pathway recombination
A3772_13655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A3772_13660	COG0295	cytidine deaminase activity
A3772_13665	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A3772_13670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A3772_13675	COG1480	7TM receptor with intracellular HD hydrolase
A3772_13685	COG1702	phosphate starvation-inducible protein PhoH
A3772_13690	COG0561	phosphatase activity
A3772_13705	COG4864	UPF0365 protein
A3772_13710	COG1030	water channel activity
A3772_13715	COG1610	YqeY-like protein
A3772_13720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A3772_13725	COG1283	sodium-dependent phosphate transmembrane transporter activity
A3772_13730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3772_13735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A3772_13740	COG2264	protein methyltransferase activity
A3772_13745	COG0484	heat shock protein binding
A3772_13750	COG0443	Heat shock 70 kDa protein
A3772_13755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A3772_13760	COG1420	regulation of RNA biosynthetic process
A3772_13765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A3772_13770	COG0481	GTPase activity
A3772_13780	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3772_13785	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A3772_13790	COG0268	Binds directly to 16S ribosomal RNA
A3772_13795	COG1466	dna polymerase III delta subunit
A3772_13805	COG2333	competence protein COMEC
A3772_13805	COG0658	competence protein
A3772_13810	COG2131	deaminase
A3772_13815	COG1555	photosystem II stabilization
A3772_13815	COG1596	polysaccharide export
A3772_13820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3772_13825	COG2226	methyltransferase
A3772_13830	COG0799	negative regulation of ribosome biogenesis
A3772_13835	COG1713	HD superfamily hydrolase involved in NAD metabolism
A3772_13840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A3772_13845	COG1534	Rna-binding protein
A3772_13850	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A3772_13855	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A3772_13860	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A3772_13875	COG2755	lipolytic protein G-D-S-L family
A3772_13880	COG3409	Peptidoglycan-binding domain 1 protein
A3772_13880	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3772_13885	COG0398	Pfam SNARE associated Golgi protein
A3772_13890	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A3772_13900	COG3209	COG3209 Rhs family protein
A3772_13910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A3772_13915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A3772_13920	COG0798	PFAM Bile acid sodium symporter
A3772_13925	COG0346	lactoylglutathione lyase activity
A3772_13930	COG0640	Transcriptional regulator
A3772_13935	COG3403	YqcI/YcgG family
A3772_13940	COG0457	Tetratricopeptide repeat
A3772_13955	COG5444	nuclease activity
A3772_13980	COG3409	Peptidoglycan-binding domain 1 protein
A3772_13980	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3772_13985	COG4824	toxin secretion phage lysis holin
A3772_14015	COG3778	Protein conserved in bacteria
A3772_14020	COG3299	homolog of phage Mu protein gp47
A3772_14025	COG3628	GPW Gp25 family protein
A3772_14035	COG4193	domain, Protein
A3772_14040	COG1652	LysM domain
A3772_14045	COG5280	Phage tail tape measure protein TP901
A3772_14045	COG3953	SLT domain
A3772_14105	COG4653	Phage capsid family
A3772_14110	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A3772_14120	COG2369	cell adhesion
A3772_14125	COG5518	Phage portal protein
A3772_14130	COG1783	phage Terminase large subunit
A3772_14135	COG5484	DNA packaging
A3772_14145	COG3677	Transposase
A3772_14160	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
A3772_14175	COG1484	DNA-dependent DNA replication
A3772_14180	COG3935	DnaD domain protein
A3772_14185	COG3723	Recombinational DNA repair protein, rece pathway
A3772_14190	COG5377	YqaJ viral recombinase family
A3772_14215	COG1476	TRANSCRIPTIONal
A3772_14220	COG3620	sequence-specific DNA binding
A3772_14230	COG0563	adenylate kinase activity
A3772_14235	COG2856	Zn peptidase
A3772_14250	COG3223	Belongs to the PsiE family
A3772_14255	COG0642	Histidine kinase
A3772_14255	COG5002	protein histidine kinase activity
A3772_14260	COG0745	RESPONSE REGULATOR receiver
A3772_14265	COG2311	Membrane
A3772_14275	COG0454	-acetyltransferase
A3772_14280	COG2249	NAD(P)H dehydrogenase (quinone) activity
A3772_14290	COG0730	response to heat
A3772_14295	COG0425	Belongs to the sulfur carrier protein TusA family
A3772_14300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A3772_14300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3772_14310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A3772_14310	COG0425	Belongs to the sulfur carrier protein TusA family
A3772_14315	COG2210	Belongs to the sulfur carrier protein TusA family
A3772_14320	COG1937	Protein conserved in bacteria
A3772_14325	COG0662	Cupin 2, conserved barrel domain protein
A3772_14340	COG0789	Transcriptional regulator
A3772_14340	COG4978	Transcriptional regulator
A3772_14345	COG2814	Major facilitator Superfamily
A3772_14350	COG0456	acetyltransferase
A3772_14355	COG1253	flavin adenine dinucleotide binding
A3772_14365	COG0697	spore germination
A3772_14370	COG0583	DNA-binding transcription factor activity
A3772_14375	COG2072	flavoprotein involved in K transport
A3772_14380	COG1230	cation diffusion facilitator family transporter
A3772_14385	COG1942	4-Oxalocrotonate Tautomerase
A3772_14390	COG0583	DNA-binding transcription factor activity
A3772_14400	COG1114	Component of the transport system for branched-chain amino acids
A3772_14405	COG1687	branched-chain amino acid
A3772_14410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A3772_14415	COG1522	sequence-specific DNA binding
A3772_14420	COG2732	(Barnase) inhibitor
A3772_14425	COG2124	cytochrome p450
A3772_14435	COG1335	isochorismatase
A3772_14445	COG2318	DinB family
A3772_14455	COG2070	2-Nitropropane dioxygenase
A3772_14460	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A3772_14475	COG3443	Belongs to the bacterial solute-binding protein 9 family
A3772_14480	COG1595	DNA-templated transcription, initiation
A3772_14485	COG0667	Aldo Keto reductase
A3772_14490	COG2851	Citrate transporter
A3772_14495	COG0583	DNA-binding transcription factor activity
A3772_14500	COG2828	Protein conserved in bacteria
A3772_14505	COG3409	Peptidoglycan-binding domain 1 protein
A3772_14510	COG5566	PFAM Mor transcription activator
A3772_14515	COG0596	Alpha beta hydrolase
A3772_14520	COG4991	sh3 domain protein
A3772_14525	COG4991	sh3 domain protein
A3772_14530	COG0346	lactoylglutathione lyase activity
A3772_14540	COG5577	PFAM Coat F domain
A3772_14545	COG1063	alcohol dehydrogenase
A3772_14555	COG5577	PFAM Coat F domain
A3772_14560	COG0789	Transcriptional regulator
A3772_14570	COG1064	alcohol dehydrogenase
A3772_14575	COG0693	protein deglycase activity
A3772_14580	COG1621	beta-fructofuranosidase activity
A3772_14585	COG3716	PTS system mannose fructose sorbose family IID component
A3772_14590	COG3715	PTS system
A3772_14595	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3772_14600	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3772_14605	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A3772_14605	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A3772_14610	COG1113	amino acid transport
A3772_14615	COG1280	lysine exporter protein (LysE YggA)
A3772_14620	COG1378	Sugar-specific transcriptional regulator TrmB
A3772_14625	COG1595	DNA-templated transcription, initiation
A3772_14635	COG2755	lipolytic protein G-D-S-L family
A3772_14635	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A3772_14645	COG2124	cytochrome p450
A3772_14645	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A3772_14650	COG1309	transcriptional regulator
A3772_14655	COG2226	methyltransferase
A3772_14665	COG2116	formate transmembrane transporter activity
A3772_14670	COG5609	conserved protein (DUF2294)
A3772_14675	COG3383	formate dehydrogenase (NAD+) activity
A3772_14680	COG2427	Protein of unknown function (DUF1641)
A3772_14690	COG0626	cystathionine gamma-synthase activity
A3772_14695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3772_14700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A3772_14705	COG2226	methyltransferase
A3772_14720	COG0768	penicillin binding
A3772_14725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A3772_14730	COG0572	uridine kinase
A3772_14750	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A3772_14755	COG3906	Belongs to the UPF0473 family
A3772_14760	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A3772_14765	COG4472	Bacterial protein of unknown function (DUF965)
A3772_14770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3772_14775	COG0628	permease
A3772_14780	COG1126	abc transporter atp-binding protein
A3772_14785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3772_14790	COG0765	amino acid transport
A3772_14795	COG0765	amino acid transport
A3772_14810	COG3881	PFAM PRC-barrel domain
A3772_14815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A3772_14820	COG0457	Tetratricopeptide repeat
A3772_14825	COG0482	sulfurtransferase activity
A3772_14830	COG1104	cysteine desulfurase activity
A3772_14835	COG1959	2 iron, 2 sulfur cluster binding
A3772_14840	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3772_14845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A3772_14855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A3772_14860	COG0124	histidyl-tRNA synthetase
A3772_14870	COG4991	sh3 domain protein
A3772_14870	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3772_14870	COG3103	Sh3 type 3 domain protein
A3772_14875	COG1490	D-aminoacyl-tRNA deacylase activity
A3772_14880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A3772_14885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3772_14890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A3772_14890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A3772_14895	COG5416	Lipopolysaccharide assembly protein A domain
A3772_14900	COG0490	domain, Protein
A3772_14905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3772_14905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3772_14915	COG2244	polysaccharide biosynthetic process
A3772_14920	COG2323	membrane
A3772_14930	COG1862	Preprotein translocase
A3772_14935	COG0343	queuine tRNA-ribosyltransferase activity
A3772_14940	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A3772_14950	COG2255	four-way junction helicase activity
A3772_14955	COG0632	four-way junction helicase activity
A3772_14965	COG2814	Major facilitator Superfamily
A3772_14970	COG0673	inositol 2-dehydrogenase activity
A3772_14975	COG2112	serine threonine protein kinase
A3772_14995	COG1115	amino acid carrier protein
A3772_15000	COG0217	transcriptional regulatory protein
A3772_15010	COG1388	LysM domain
A3772_15015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A3772_15020	COG0157	Belongs to the NadC ModD family
A3772_15025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3772_15030	COG1104	cysteine desulfurase activity
A3772_15035	COG1827	regulation of RNA biosynthetic process
A3772_15040	COG0077	Prephenate dehydratase
A3772_15045	COG4492	Belongs to the UPF0735 family
A3772_15050	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3772_15055	COG3290	protein histidine kinase activity
A3772_15065	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A3772_15070	COG2868	ribosomal protein
A3772_15075	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A3772_15080	COG1994	Peptidase M50
A3772_15085	COG0739	heme binding
A3772_15090	COG2894	cell division
A3772_15095	COG0850	regulation of cytokinetic process
A3772_15100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A3772_15105	COG1792	Involved in formation and maintenance of cell shape
A3772_15110	COG1077	Cell shape determining protein MreB Mrl
A3772_15115	COG2003	Belongs to the UPF0758 family
A3772_15120	COG0424	maF-like protein
A3772_15130	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A3772_15135	COG0285	dihydrofolate synthase activity
A3772_15140	COG0525	valine-tRNA ligase activity
A3772_15150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A3772_15155	COG1388	LysM domain
A3772_15160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A3772_15165	COG0113	porphobilinogen synthase activity
A3772_15170	COG1587	Uroporphyrinogen-III synthase
A3772_15175	COG0181	hydroxymethylbilane synthase activity
A3772_15180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A3772_15185	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A3772_15195	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A3772_15200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A3772_15205	COG1067	ATP-dependent peptidase activity
A3772_15205	COG0470	DNA polymerase III
A3772_15210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A3772_15215	COG0544	peptidyl-prolyl cis-trans isomerase activity
A3772_15220	COG1477	protein flavinylation
A3772_15220	COG0457	Tetratricopeptide repeat
A3772_15225	COG0066	3-isopropylmalate dehydratase activity
A3772_15230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A3772_15235	COG0473	3-isopropylmalate dehydrogenase activity
A3772_15240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A3772_15245	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A3772_15250	COG0440	acetolactate synthase activity
A3772_15255	COG0028	Belongs to the TPP enzyme family
A3772_15265	COG0454	-acetyltransferase
A3772_15275	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
A3772_15285	COG0622	Phosphoesterase
A3772_15290	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A3772_15295	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A3772_15300	COG5401	PFAM Sporulation and spore germination
A3772_15305	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A3772_15310	COG1846	Transcriptional regulator
A3772_15315	COG2197	response regulator
A3772_15320	COG0824	Thioesterase
A3772_15325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A3772_15330	COG1053	succinate dehydrogenase
A3772_15335	COG2009	succinate dehydrogenase
A3772_15345	COG1719	4-vinyl reductase, 4VR
A3772_15350	COG0527	aspartate kinase activity
A3772_15355	COG0322	excinuclease ABC activity
A3772_15360	COG3118	belongs to the thioredoxin family
A3772_15365	COG3534	alpha-L-arabinofuranosidase
A3772_15370	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A3772_15375	COG2086	electron transfer activity
A3772_15380	COG1024	Enoyl-CoA hydratase
A3772_15385	COG1309	transcriptional regulator
A3772_15390	COG0318	PFAM AMP-dependent synthetase and ligase
A3772_15395	COG3766	membrane
A3772_15400	COG1193	negative regulation of DNA recombination
A3772_15405	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A3772_15405	COG1796	DNA polymerase
A3772_15410	COG1286	toxin biosynthetic process
A3772_15415	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
A3772_15420	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A3772_15425	COG0072	phenylalanine-tRNA ligase activity
A3772_15425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3772_15430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A3772_15440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A3772_15450	COG3835	regulator
A3772_15455	COG0277	FAD linked oxidase domain protein
A3772_15460	COG0247	lactate metabolic process
A3772_15465	COG0346	lactoylglutathione lyase activity
A3772_15475	COG1966	Carbon starvation protein
A3772_15480	COG3534	alpha-L-arabinofuranosidase
A3772_15485	COG0395	ABC-type sugar transport system, permease component
A3772_15490	COG1175	transmembrane transport
A3772_15495	COG1653	transport
A3772_15500	COG0371	Dehydrogenase
A3772_15505	COG0647	UMP catabolic process
A3772_15510	COG0235	Class ii aldolase
A3772_15515	COG1069	ribulokinase activity
A3772_15520	COG2160	L-arabinose isomerase activity
A3772_15525	COG3507	Belongs to the glycosyl hydrolase 43 family
A3772_15530	COG1363	Peptidase, m42
A3772_15540	COG3326	Membrane
A3772_15545	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A3772_15550	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A3772_15555	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A3772_15565	COG1346	cytolysis
A3772_15570	COG1380	Effector of murein hydrolase LrgA
A3772_15575	COG3279	Response regulator of the LytR AlgR family
A3772_15580	COG3275	phosphorelay sensor kinase activity
A3772_15590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3772_15600	COG0398	Pfam SNARE associated Golgi protein
A3772_15605	COG1484	DNA-dependent DNA replication
A3772_15610	COG3611	Membrane attachment protein
A3772_15615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A3772_15620	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A3772_15625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A3772_15630	COG1733	regulation of RNA biosynthetic process
A3772_15635	COG2814	Major facilitator Superfamily
A3772_15640	COG0656	L-ascorbic acid biosynthetic process
A3772_15645	COG0237	dephospho-CoA kinase activity
A3772_15660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A3772_15665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A3772_15665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A3772_15670	COG5002	protein histidine kinase activity
A3772_15675	COG0745	RESPONSE REGULATOR receiver
A3772_15680	COG0039	L-malate dehydrogenase activity
A3772_15685	COG0538	isocitrate dehydrogenase activity
A3772_15690	COG0372	Belongs to the citrate synthase family
A3772_15695	COG2707	UPF0756 membrane protein
A3772_15700	COG0628	permease
A3772_15705	COG3030	protein affecting phage T7 exclusion by the F plasmid
A3772_15710	COG0469	pyruvate kinase activity
A3772_15715	COG0205	6-phosphofructokinase activity
A3772_15720	COG0825	malonyl-CoA metabolic process
A3772_15725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A3772_15730	COG0281	malic enzyme
A3772_15735	COG0587	DNA-directed DNA polymerase activity
A3772_15755	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A3772_15765	COG4109	DRTGG domain
A3772_15775	COG0730	response to heat
A3772_15780	COG1473	amidohydrolase
A3772_15785	COG0196	riboflavin kinase activity
A3772_15790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3772_15795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A3772_15800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3772_15805	COG1126	abc transporter atp-binding protein
A3772_15810	COG0765	amino acid transport
A3772_15815	COG0765	amino acid transport
A3772_15820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3772_15825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3772_15830	COG0454	-acetyltransferase
A3772_15835	COG0583	DNA-binding transcription factor activity
A3772_15840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3772_15845	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_15855	COG0165	Argininosuccinate lyase
A3772_15860	COG0137	argininosuccinate synthase activity
A3772_15865	COG0521	Mo-molybdopterin cofactor biosynthetic process
A3772_15870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A3772_15875	COG0827	DNA restriction-modification system
A3772_15880	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A3772_15885	COG3874	Sporulation protein YtfJ
A3772_15895	COG1714	RDD family
A3772_15900	COG0616	signal peptide processing
A3772_15905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3772_15910	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A3772_15915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3772_15925	COG0301	tRNA thio-modification
A3772_15930	COG1104	cysteine desulfurase activity
A3772_15935	COG1114	Component of the transport system for branched-chain amino acids
A3772_15940	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
A3772_15945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A3772_15950	COG1309	transcriptional regulator
A3772_15955	COG1956	GAF domain-containing protein
A3772_15960	COG2203	Gaf domain
A3772_15960	COG2199	diguanylate cyclase activity
A3772_15965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A3772_15975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A3772_15980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3772_15985	COG0454	-acetyltransferase
A3772_15990	COG0517	IMP dehydrogenase activity
A3772_15995	COG0123	including yeast histone deacetylase and acetoin utilization protein
A3772_16000	COG1360	Flagellar Motor Protein
A3772_16005	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A3772_16010	COG1609	Transcriptional regulator
A3772_16015	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A3772_16015	COG1605	Chorismate mutase
A3772_16020	COG3118	belongs to the thioredoxin family
A3772_16025	COG4980	gas vesicle protein
A3772_16030	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
A3772_16035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A3772_16040	COG1674	ftsk spoiiie
A3772_16045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3772_16050	COG4848	Belongs to the UPF0354 family
A3772_16055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_16065	COG1363	Peptidase, m42
A3772_16070	COG5584	Small secreted protein
A3772_16075	COG0281	malic enzyme
A3772_16080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3772_16085	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A3772_16095	COG0510	thiamine kinase activity
A3772_16100	COG1523	belongs to the glycosyl hydrolase 13 family
A3772_16105	COG1597	lipid kinase activity
A3772_16115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A3772_16120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3772_16125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3772_16130	COG2252	PERMEase
A3772_16135	COG4473	ABC transporter
A3772_16140	COG1131	(ABC) transporter
A3772_16145	COG1349	DNA-binding transcription factor activity
A3772_16150	COG1187	pseudouridine synthase activity
A3772_16155	COG2244	polysaccharide biosynthetic process
A3772_16160	COG2081	HI0933 family
A3772_16165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A3772_16175	COG5578	integral membrane protein
A3772_16180	COG0673	inositol 2-dehydrogenase activity
A3772_16185	COG1653	transport
A3772_16190	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A3772_16195	COG4209	transmembrane transport
A3772_16200	COG2207	Transcriptional regulator
A3772_16205	COG1653	transport
A3772_16210	COG0395	ABC-type sugar transport system, permease component
A3772_16215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3772_16220	COG2124	cytochrome p450
A3772_16225	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A3772_16230	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A3772_16235	COG0156	8-amino-7-oxononanoate synthase activity
A3772_16240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3772_16245	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
A3772_16250	COG1073	alpha beta
A3772_16275	COG1486	melibiose metabolic process
A3772_16280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A3772_16285	COG0495	leucyl-tRNA aminoacylation
A3772_16295	COG2202	Pas domain
A3772_16295	COG1366	Belongs to the anti-sigma-factor antagonist family
A3772_16300	COG2814	Major facilitator Superfamily
A3772_16305	COG2433	Pfam Transposase IS66
A3772_16310	COG0577	efflux transmembrane transporter activity
A3772_16315	COG1136	(ABC) transporter
A3772_16320	COG2205	protein histidine kinase activity
A3772_16325	COG0745	RESPONSE REGULATOR receiver
A3772_16330	COG0577	efflux transmembrane transporter activity
A3772_16335	COG1136	(ABC) transporter
A3772_16350	COG1131	(ABC) transporter
A3772_16355	COG1725	Transcriptional regulator
A3772_16370	COG1242	4 iron, 4 sulfur cluster binding
A3772_16375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A3772_16385	COG2267	carboxylic ester hydrolase activity
A3772_16390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A3772_16395	COG1113	amino acid transport
A3772_16400	COG0367	asparagine synthase
A3772_16405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A3772_16410	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A3772_16420	COG1506	peptidase
A3772_16425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3772_16430	COG1116	anion transmembrane transporter activity
A3772_16435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3772_16440	COG0494	nUDIX hydrolase
A3772_16445	COG4824	toxin secretion phage lysis holin
A3772_16450	COG0783	Belongs to the Dps family
A3772_16465	COG1854	S-ribosylhomocysteine lyase activity
A3772_16470	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A3772_16475	COG0288	reversible hydration of carbon dioxide
A3772_16480	COG0254	rRNA binding
A3772_16485	COG1271	oxidase subunit
A3772_16490	COG1294	oxidase, subunit
A3772_16500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A3772_16505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A3772_16505	COG1321	iron dependent repressor
A3772_16510	COG1121	(ABC) transporter
A3772_16515	COG0803	Belongs to the bacterial solute-binding protein 9 family
A3772_16520	COG4948	Mandelate Racemase Muconate Lactonizing
A3772_16525	COG0318	PFAM AMP-dependent synthetase and ligase
A3772_16530	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A3772_16535	COG0596	Alpha beta hydrolase
A3772_16540	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
A3772_16545	COG1169	isochorismate synthase
A3772_16550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A3772_16555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3772_16560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3772_16565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3772_16570	COG0438	transferase activity, transferring glycosyl groups
A3772_16580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A3772_16585	COG0438	transferase activity, transferring glycosyl groups
A3772_16590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A3772_16595	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
A3772_16600	COG0058	SHG alpha-glucan phosphorylase activity
A3772_16605	COG0297	glycogen (starch) synthase activity
A3772_16610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A3772_16615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A3772_16620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A3772_16750	COG3859	Proton-coupled thiamine transporter YuaJ
A3772_16755	COG1247	-acetyltransferase
A3772_16760	COG2268	Band 7 protein
A3772_16765	COG1585	Membrane protein implicated in regulation of membrane protease activity
A3772_16770	COG2318	DinB family
A3772_16780	COG1454	alcohol dehydrogenase
A3772_16790	COG1510	regulation of RNA biosynthetic process
A3772_16800	COG0569	domain protein
A3772_16805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3772_16810	COG4682	membrane
A3772_16815	COG1705	Flagellar rod assembly protein muramidase FlgJ
A3772_16820	COG0477	Major facilitator Superfamily
A3772_16825	COG5553	Cysteine dioxygenase type I
A3772_16835	COG1968	undecaprenyl-diphosphatase activity
A3772_16840	COG0628	permease
A3772_16845	COG0673	inositol 2-dehydrogenase activity
A3772_16850	COG4806	L-rhamnose isomerase
A3772_16855	COG3254	rhamnose metabolic process
A3772_16860	COG1070	Carbohydrate kinase
A3772_16865	COG1349	DNA-binding transcription factor activity
A3772_16870	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_16870	COG3347	Dehydrogenase
A3772_16875	COG0840	transmembrane signaling receptor activity
A3772_16880	COG0840	transmembrane signaling receptor activity
A3772_16885	COG0840	transmembrane signaling receptor activity
A3772_16890	COG0840	transmembrane signaling receptor activity
A3772_16905	COG0432	Pfam Uncharacterised protein family UPF0047
A3772_16910	COG0366	Alpha amylase catalytic
A3772_16915	COG1253	flavin adenine dinucleotide binding
A3772_16920	COG2738	Putative neutral zinc metallopeptidase
A3772_16935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A3772_16950	COG0166	Belongs to the GPI family
A3772_16955	COG1979	alcohol dehydrogenase
A3772_16960	COG1979	alcohol dehydrogenase
A3772_16965	COG2155	Conserved Protein
A3772_16970	COG1098	S1 RNA binding domain
A3772_16975	COG0436	Aminotransferase
A3772_16980	COG1522	sequence-specific DNA binding
A3772_16985	COG2267	carboxylic ester hydrolase activity
A3772_16995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A3772_17000	COG2205	protein histidine kinase activity
A3772_17010	COG5018	Exonuclease
A3772_17020	COG2814	Major facilitator Superfamily
A3772_17025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3772_17030	COG3011	Protein conserved in bacteria
A3772_17040	COG3290	protein histidine kinase activity
A3772_17045	COG4565	transcriptional regulatory protein
A3772_17070	COG3493	citrate carrier protein
A3772_17080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3772_17080	COG2111	Na H antiporter
A3772_17085	COG2111	Na H antiporter
A3772_17090	COG1006	Multisubunit Na H antiporter MnhC subunit
A3772_17095	COG0651	ATP synthesis coupled electron transport
A3772_17100	COG1863	multisubunit Na H antiporter MnhE subunit
A3772_17105	COG2212	antiporter activity
A3772_17110	COG1320	monovalent cation:proton antiporter activity
A3772_17115	COG2050	protein possibly involved in aromatic compounds catabolism
A3772_17120	COG2197	response regulator
A3772_17125	COG4585	Histidine kinase
A3772_17135	COG0142	geranyltranstransferase activity
A3772_17150	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
A3772_17155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A3772_17160	COG1335	isochorismatase
A3772_17165	COG5506	Protein of unknown function (DUF1694)
A3772_17180	COG0628	permease
A3772_17195	COG1418	mRNA catabolic process
A3772_17200	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_17210	COG1511	domain protein
A3772_17215	COG0433	COG0433 Predicted ATPase
A3772_17215	COG1674	ftsk spoiiie
A3772_17220	COG4499	WXG100 protein secretion system (Wss), protein YukC
A3772_17225	COG5417	Belongs to the EsaB family
A3772_17230	COG4842	Belongs to the WXG100 family
A3772_17235	COG2508	Transcriptional regulator
A3772_17235	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A3772_17240	COG0686	Belongs to the AlaDH PNT family
A3772_17245	COG5634	Uncharacterized conserved protein (DUF2278)
A3772_17250	COG3251	PFAM MbtH domain protein
A3772_17255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_17260	COG3433	isochorismatase activity
A3772_17260	COG1535	isochorismatase
A3772_17265	COG1021	2,3-dihydroxybenzoate-AMP ligase
A3772_17270	COG1169	isochorismate synthase
A3772_17275	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_17280	COG2819	hydrolase of the alpha beta superfamily
A3772_17285	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A3772_17290	COG1268	BioY protein
A3772_17295	COG2056	Na+-H+ antiporter family
A3772_17300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A3772_17305	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A3772_17310	COG3584	3D domain protein
A3772_17325	COG1252	NADH dehydrogenase
A3772_17330	COG0492	ferredoxin-NADP+ reductase activity
A3772_17340	COG0516	GMP reductase activity
A3772_17345	COG2808	Putative FMN-binding domain
A3772_17350	COG0456	acetyltransferase
A3772_17355	COG0316	Belongs to the HesB IscA family
A3772_17360	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A3772_17365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A3772_17370	COG4844	belongs to the
A3772_17375	COG1252	NADH dehydrogenase
A3772_17380	COG4837	Protein of unknown function (DUF1462)
A3772_17385	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A3772_17390	COG1506	peptidase
A3772_17390	COG4946	Tricorn protease homolog
A3772_17390	COG0823	Involved in the tonB-independent uptake of proteins
A3772_17395	COG0083	homoserine kinase activity
A3772_17400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3772_17405	COG0460	homoserine dehydrogenase
A3772_17410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A3772_17415	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A3772_17420	COG0647	UMP catabolic process
A3772_17425	COG2445	Protein of unknown function DUF86
A3772_17430	COG4470	Protein conserved in bacteria
A3772_17440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A3772_17445	COG0739	heme binding
A3772_17455	COG3377	Domain of unknown function (DUF1805)
A3772_17460	COG0737	Belongs to the 5'-nucleotidase family
A3772_17465	COG0730	response to heat
A3772_17470	COG1801	Protein of unknown function DUF72
A3772_17480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3772_17485	COG2508	Transcriptional regulator
A3772_17490	COG2233	PERMEase
A3772_17495	COG2233	PERMEase
A3772_17500	COG3195	allantoin biosynthetic process
A3772_17500	COG3648	Uricase
A3772_17505	COG2351	hydroxyisourate hydrolase activity
A3772_17515	COG2080	2 iron, 2 sulfur cluster binding
A3772_17520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A3772_17525	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
A3772_17530	COG2068	MobA-Related Protein
A3772_17535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A3772_17540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A3772_17545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3772_17555	COG2356	endonuclease I
A3772_17560	COG3842	ATPase activity
A3772_17565	COG2188	Transcriptional regulator
A3772_17570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3772_17575	COG0395	ABC-type sugar transport system, permease component
A3772_17580	COG1175	transmembrane transport
A3772_17585	COG1653	transport
A3772_17590	COG2222	sugar isomerase
A3772_17595	COG0322	excinuclease ABC activity
A3772_17600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3772_17615	COG0346	lactoylglutathione lyase activity
A3772_17620	COG0640	Transcriptional regulator
A3772_17625	COG0719	Fe-S assembly protein
A3772_17630	COG0822	iron-sulfur transferase activity
A3772_17635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3772_17640	COG0719	Fe-S assembly protein
A3772_17645	COG0396	ATPase activity
A3772_17655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3772_17660	COG1464	Belongs to the NlpA lipoprotein family
A3772_17665	COG2011	ABC-type metal ion transport system permease component
A3772_17670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A3772_17680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3772_17685	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A3772_17695	COG0509	glycine decarboxylation via glycine cleavage system
A3772_17700	COG1393	Belongs to the ArsC family
A3772_17705	COG1960	acyl-CoA dehydrogenase activity
A3772_17710	COG0183	Belongs to the thiolase family
A3772_17715	COG1024	Enoyl-CoA hydratase
A3772_17715	COG1250	3-hydroxyacyl-CoA dehydrogenase
A3772_17725	COG0506	proline dehydrogenase activity
A3772_17735	COG5577	PFAM Coat F domain
A3772_17740	COG1846	Transcriptional regulator
A3772_17745	COG0477	Major facilitator Superfamily
A3772_17750	COG1942	4-Oxalocrotonate Tautomerase
A3772_17755	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_17760	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_17765	COG0583	DNA-binding transcription factor activity
A3772_17775	COG1120	ATPase activity
A3772_17795	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_17800	COG0783	Belongs to the Dps family
A3772_17805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3772_17810	COG0745	RESPONSE REGULATOR receiver
A3772_17815	COG2205	protein histidine kinase activity
A3772_17815	COG2770	Histidine kinase
A3772_17825	COG1309	transcriptional regulator
A3772_17830	COG0114	fumarate hydratase activity
A3772_17840	COG0697	spore germination
A3772_17845	COG0814	amino acid
A3772_17855	COG2197	response regulator
A3772_17860	COG4585	Histidine kinase
A3772_17865	COG4758	membrane
A3772_17870	COG3595	metallopeptidase activity
A3772_17875	COG1842	Phage shock protein A
A3772_17880	COG4758	membrane
A3772_17885	COG2814	Major facilitator Superfamily
A3772_17890	COG2096	Adenosyltransferase
A3772_17895	COG1120	ATPase activity
A3772_17900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3772_17905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3772_17910	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_17915	COG3386	PFAM SMP-30 Gluconolaconase
A3772_17920	COG2205	protein histidine kinase activity
A3772_17925	COG0745	RESPONSE REGULATOR receiver
A3772_17935	COG1191	sigma factor activity
A3772_17945	COG2140	Oxalate decarboxylase
A3772_17955	COG0577	efflux transmembrane transporter activity
A3772_17960	COG1136	(ABC) transporter
A3772_17965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A3772_17970	COG1120	ATPase activity
A3772_17975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3772_17980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3772_17985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3772_17995	COG0531	amino acid
A3772_18005	COG1988	membrane-bound metal-dependent
A3772_18010	COG1368	sulfuric ester hydrolase activity
A3772_18015	COG1910	domain protein
A3772_18020	COG0725	ABC transporter, periplasmic molybdate-binding protein
A3772_18025	COG4149	molybdate abc transporter
A3772_18030	COG0656	L-ascorbic acid biosynthetic process
A3772_18040	COG0025	NhaP-type Na H and K H
A3772_18045	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3772_18050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A3772_18055	COG3973	AAA domain
A3772_18060	COG2860	membrane
A3772_18065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A3772_18070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A3772_18075	COG2217	Heavy metal translocating P-type atpase
A3772_18080	COG2217	Heavy metal translocating P-type atpase
A3772_18085	COG2608	mercury ion transmembrane transporter activity
A3772_18090	COG1937	Protein conserved in bacteria
A3772_18095	COG0673	inositol 2-dehydrogenase activity
A3772_18100	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A3772_18105	COG1289	transmembrane transporter activity
A3772_18115	COG2076	Multidrug Resistance protein
A3772_18120	COG1309	transcriptional regulator
A3772_18125	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_18135	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A3772_18140	COG0557	exoribonuclease II activity
A3772_18145	COG1647	Serine aminopeptidase, S33
A3772_18150	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A3772_18155	COG0596	Alpha beta hydrolase
A3772_18160	COG1476	TRANSCRIPTIONal
A3772_18165	COG1396	sequence-specific DNA binding
A3772_18170	COG1396	sequence-specific DNA binding
A3772_18175	COG1733	regulation of RNA biosynthetic process
A3772_18180	COG0840	transmembrane signaling receptor activity
A3772_18185	COG1174	glycine betaine transport
A3772_18190	COG1732	Glycine betaine
A3772_18195	COG1174	glycine betaine transport
A3772_18200	COG0517	IMP dehydrogenase activity
A3772_18200	COG1125	glycine betaine transport
A3772_18205	COG1510	regulation of RNA biosynthetic process
A3772_18225	COG5658	integral membrane protein
A3772_18230	COG0640	Transcriptional regulator
A3772_18235	COG1174	glycine betaine transport
A3772_18240	COG1732	Glycine betaine
A3772_18245	COG1174	glycine betaine transport
A3772_18250	COG0517	IMP dehydrogenase activity
A3772_18250	COG1125	glycine betaine transport
A3772_18255	COG1510	regulation of RNA biosynthetic process
A3772_18260	COG2095	MarC family integral membrane protein
A3772_18270	COG3064	Membrane
A3772_18275	COG4640	response to antibiotic
A3772_18280	COG0456	acetyltransferase
A3772_18285	COG0148	phosphopyruvate hydratase activity
A3772_18290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A3772_18295	COG0149	triose-phosphate isomerase activity
A3772_18300	COG0126	phosphoglycerate kinase activity
A3772_18310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A3772_18315	COG2390	Transcriptional regulator
A3772_18320	COG2814	Major facilitator Superfamily
A3772_18325	COG1609	Transcriptional regulator
A3772_18330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3772_18335	COG0583	DNA-binding transcription factor activity
A3772_18340	COG0697	spore germination
A3772_18345	COG1113	amino acid transport
A3772_18350	COG3858	chitin binding
A3772_18355	COG1556	Lactate utilization protein
A3772_18360	COG1139	Iron-sulfur cluster binding protein
A3772_18365	COG0247	lactate metabolic process
A3772_18370	COG2197	response regulator
A3772_18375	COG4585	Histidine kinase
A3772_18380	COG0842	Transport permease protein
A3772_18385	COG1131	(ABC) transporter
A3772_18390	COG0596	Alpha beta hydrolase
A3772_18395	COG2208	phosphoserine phosphatase activity
A3772_18400	COG3867	Arabinogalactan endo-beta-1,4-galactanase
A3772_18405	COG1874	Beta-galactosidase
A3772_18410	COG3833	ABC-type maltose transport systems, permease component
A3772_18415	COG1175	transmembrane transport
A3772_18420	COG2182	Extracellular solute-binding protein
A3772_18425	COG1609	Transcriptional regulator
A3772_18430	COG2186	Transcriptional regulator
A3772_18435	COG1620	l-lactate permease
A3772_18440	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A3772_18450	COG5039	Polysaccharide pyruvyl transferase
A3772_18455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A3772_18460	COG0110	maltose O-acetyltransferase activity
A3772_18465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A3772_18470	COG2244	polysaccharide biosynthetic process
A3772_18475	COG1216	Glycosyl transferase, family 2
A3772_18480	COG5039	Polysaccharide pyruvyl transferase
A3772_18485	COG1216	Glycosyl transferase, family 2
A3772_18495	COG0438	transferase activity, transferring glycosyl groups
A3772_18500	COG1215	transferase activity, transferring glycosyl groups
A3772_18505	COG0438	transferase activity, transferring glycosyl groups
A3772_18510	COG1086	Polysaccharide biosynthesis protein
A3772_18515	COG0489	protein tyrosine kinase activity
A3772_18520	COG3944	biosynthesis protein
A3772_18525	COG1396	sequence-specific DNA binding
A3772_18530	COG2272	Belongs to the type-B carboxylesterase lipase family
A3772_18540	COG3479	Phenolic acid decarboxylase
A3772_18550	COG1794	racemase activity, acting on amino acids and derivatives
A3772_18555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3772_18560	COG1621	beta-fructofuranosidase activity
A3772_18565	COG1621	beta-fructofuranosidase activity
A3772_18570	COG0531	amino acid
A3772_18575	COG1309	transcriptional regulator
A3772_18580	COG2076	Multidrug Resistance protein
A3772_18585	COG2076	Multidrug Resistance protein
A3772_18595	COG0277	FAD linked oxidase domain protein
A3772_18600	COG3621	Patatin-like phospholipase
A3772_18610	COG0740	serine-type endopeptidase activity
A3772_18615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A3772_18620	COG0366	Alpha amylase catalytic
A3772_18625	COG1554	hydrolase, family 65, central catalytic
A3772_18630	COG5521	maltodextrose utilization protein MalA
A3772_18635	COG3833	ABC-type maltose transport systems, permease component
A3772_18640	COG1175	transmembrane transport
A3772_18645	COG2182	Extracellular solute-binding protein
A3772_18650	COG0366	Alpha amylase catalytic
A3772_18655	COG1609	Transcriptional regulator
A3772_18660	COG1611	Belongs to the LOG family
A3772_18665	COG1694	Mazg nucleotide pyrophosphohydrolase
A3772_18670	COG0659	secondary active sulfate transmembrane transporter activity
A3772_18675	COG0288	reversible hydration of carbon dioxide
A3772_18680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3772_18685	COG0577	efflux transmembrane transporter activity
A3772_18690	COG1136	(ABC) transporter
A3772_18695	COG5002	protein histidine kinase activity
A3772_18700	COG0745	RESPONSE REGULATOR receiver
A3772_18710	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A3772_18715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3772_18720	COG1481	regulation of sporulation
A3772_18725	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A3772_18730	COG1660	Displays ATPase and GTPase activities
A3772_18735	COG1051	belongs to the nudix hydrolase family
A3772_18740	COG0492	ferredoxin-NADP+ reductase activity
A3772_18745	COG0791	NLP P60 protein
A3772_18745	COG3883	PFAM NLP P60 protein
A3772_18750	COG0457	Tetratricopeptide repeat
A3772_18755	COG1132	(ABC) transporter
A3772_18775	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A3772_18775	COG0140	phosphoribosyl-ATP diphosphatase activity
A3772_18780	COG0107	imidazoleglycerol-phosphate synthase activity
A3772_18785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A3772_18790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A3772_18795	COG0131	Imidazoleglycerol-phosphate dehydratase
A3772_18800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A3772_18805	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A3772_18810	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
A3772_18815	COG4990	cell redox homeostasis
A3772_18820	COG5297	Belongs to the glycosyl hydrolase family 6
A3772_18825	COG0110	maltose O-acetyltransferase activity
A3772_18830	COG0546	phosphoglycolate phosphatase activity
A3772_18835	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A3772_18840	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A3772_18845	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
A3772_18850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A3772_18855	COG0363	glucosamine-6-phosphate deaminase activity
A3772_18865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A3772_18870	COG1846	Transcriptional regulator
A3772_18875	COG2124	cytochrome p450
A3772_18885	COG1846	Transcriptional regulator
A3772_18890	COG2814	Major facilitator Superfamily
A3772_18895	COG1950	PFAM Membrane protein of
A3772_18900	COG1983	PspC domain protein
A3772_18905	COG3595	metallopeptidase activity
A3772_18920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A3772_18925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A3772_18930	COG0556	nucleotide-excision repair
A3772_18935	COG4897	Protein conserved in bacteria
A3772_18940	COG3848	Pyruvate phosphate dikinase
A3772_18940	COG0574	Belongs to the PEP-utilizing enzyme family
A3772_18945	COG1309	transcriptional regulator
A3772_18950	COG2814	Major facilitator Superfamily
A3772_18955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3772_18965	COG0793	Belongs to the peptidase S41A family
A3772_18965	COG3409	Peptidoglycan-binding domain 1 protein
A3772_18970	COG2177	Part of the ABC transporter FtsEX involved in
A3772_18975	COG2884	Cell division ATP-binding protein ftsE
A3772_18980	COG2010	Cytochrome c
A3772_18985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3772_18990	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A3772_18995	COG0653	protein targeting
A3772_19000	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A3772_19015	COG1516	flagellar protein fliS
A3772_19020	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A3772_19025	COG1334	flagellar protein FlaG
A3772_19030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A3772_19035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A3772_19040	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
A3772_19050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A3772_19055	COG4786	Flagellar basal body rod
A3772_19055	COG1256	bacterial-type flagellum assembly
A3772_19060	COG3418	PFAM FlgN family protein
A3772_19065	COG2747	anti-sigma28 factor FlgM
A3772_19075	COG1040	competence protein
A3772_19085	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A3772_19090	COG1307	EDD domain protein, DegV family
A3772_19095	COG2197	response regulator
A3772_19100	COG4585	Histidine kinase
A3772_19105	COG1739	Uncharacterized protein family UPF0029
A3772_19110	COG1316	TRANSCRIPTIONal
A3772_19115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3772_19120	COG0438	transferase activity, transferring glycosyl groups
A3772_19125	COG1215	transferase activity, transferring glycosyl groups
A3772_19130	COG3206	protein involved in exopolysaccharide biosynthesis
A3772_19135	COG3307	-O-antigen
A3772_19140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3772_19145	COG0438	transferase activity, transferring glycosyl groups
A3772_19145	COG0297	glycogen (starch) synthase activity
A3772_19150	COG2244	polysaccharide biosynthetic process
A3772_19155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A3772_19165	COG2247	cell wall binding repeat
A3772_19165	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3772_19170	COG2385	sporulation resulting in formation of a cellular spore
A3772_19170	COG2247	cell wall binding repeat
A3772_19180	COG1316	TRANSCRIPTIONal
A3772_19185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A3772_19190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3772_19195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A3772_19195	COG1215	transferase activity, transferring glycosyl groups
A3772_19200	COG0463	Glycosyl transferase, family 2
A3772_19215	COG1134	teichoic acid transport
A3772_19220	COG1682	transport, permease protein
A3772_19225	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A3772_19230	COG0438	transferase activity, transferring glycosyl groups
A3772_19235	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3772_19240	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
A3772_19245	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A3772_19255	COG4193	domain, Protein
A3772_19260	COG1482	cell wall glycoprotein biosynthetic process
A3772_19270	COG0697	spore germination
A3772_19275	COG0814	amino acid
A3772_19285	COG2814	Major facilitator Superfamily
A3772_19290	COG1316	TRANSCRIPTIONal
A3772_19295	COG0561	phosphatase activity
A3772_19300	COG0791	NLP P60 protein
A3772_19310	COG2843	Capsule synthesis protein
A3772_19320	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A3772_19325	COG1609	Transcriptional regulator
A3772_19330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3772_19335	COG1869	D-ribose catabolic process
A3772_19340	COG1129	ABC transporter
A3772_19345	COG1172	Belongs to the binding-protein-dependent transport system permease family
A3772_19350	COG1879	ABC-type sugar transport system periplasmic component
A3772_19355	COG3103	Sh3 type 3 domain protein
A3772_19365	COG2249	NAD(P)H dehydrogenase (quinone) activity
A3772_19370	COG3527	Alpha-acetolactate decarboxylase
A3772_19375	COG0028	Belongs to the TPP enzyme family
A3772_19380	COG0583	DNA-binding transcription factor activity
A3772_19385	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3772_19400	COG5337	Spore coat protein CotH
A3772_19410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A3772_19420	COG0405	Gamma-glutamyltransferase
A3772_19425	COG1522	sequence-specific DNA binding
A3772_19430	COG2059	Chromate
A3772_19435	COG2059	Chromate
A3772_19445	COG0655	NAD(P)H dehydrogenase (quinone) activity
A3772_19450	COG0583	DNA-binding transcription factor activity
A3772_19455	COG1515	deoxyribonuclease V activity
A3772_19460	COG2849	repeat protein
A3772_19465	COG5444	nuclease activity
A3772_19480	COG3878	Protein conserved in bacteria
A3772_19485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3772_19490	COG4464	protein tyrosine phosphatase activity
A3772_19495	COG0489	protein tyrosine kinase activity
A3772_19500	COG3944	biosynthesis protein
A3772_19510	COG4715	Zinc finger, swim domain protein
A3772_19515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A3772_19520	COG0561	phosphatase activity
A3772_19525	COG1349	DNA-binding transcription factor activity
A3772_19530	COG0629	single-stranded DNA binding
A3772_19545	COG3764	Sortase (surface protein transpeptidase)
A3772_19550	COG2972	Histidine kinase
A3772_19550	COG0745	RESPONSE REGULATOR receiver
A3772_19555	COG1970	mechanosensitive ion channel activity
A3772_19560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A3772_19565	COG0457	Tetratricopeptide repeat
A3772_19570	COG4786	Flagellar basal body rod
A3772_19575	COG4786	Flagellar basal body rod
A3772_19580	COG1077	Cell shape determining protein MreB Mrl
A3772_19585	COG1609	Transcriptional regulator
A3772_19590	COG1846	Transcriptional regulator
A3772_19595	COG2814	Major facilitator Superfamily
A3772_19600	COG3420	alginic acid biosynthetic process
A3772_19605	COG1953	Uracil, thiamine, allantoin
A3772_19610	COG0477	Major facilitator Superfamily
A3772_19615	COG1335	isochorismatase
A3772_19625	COG0004	ammonium transporteR
A3772_19630	COG0347	Belongs to the P(II) protein family
A3772_19635	COG0671	phosphoesterase, PA-phosphatase related
A3772_19645	COG0739	heme binding
A3772_19650	COG1247	-acetyltransferase
A3772_19670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A3772_19675	COG0789	Transcriptional regulator
A3772_19685	COG2910	NAD(P)H-binding
A3772_19690	COG1959	2 iron, 2 sulfur cluster binding
A3772_19695	COG0804	urea catabolic process
A3772_19700	COG0832	Belongs to the urease beta subunit family
A3772_19705	COG0831	urea catabolic process
A3772_19715	COG3237	CsbD-like
A3772_19720	COG1994	Peptidase M50
A3772_19725	COG0457	Tetratricopeptide repeat
A3772_19730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3772_19735	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A3772_19745	COG2304	oxidoreductase activity
A3772_19755	COG2304	oxidoreductase activity
A3772_19760	COG2385	sporulation resulting in formation of a cellular spore
A3772_19765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A3772_19775	COG4836	Membrane
A3772_19785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A3772_19790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A3772_19795	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A3772_19800	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A3772_19805	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A3772_19810	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A3772_19820	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A3772_19825	COG0356	it plays a direct role in the translocation of protons across the membrane
A3772_19835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A3772_19840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A3772_19845	COG4475	Protein of unknown function (DUF436)
A3772_19850	COG0698	ribose 5-phosphate isomerase
A3772_19855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A3772_19860	COG1971	Probably functions as a manganese efflux pump
A3772_19865	COG0009	L-threonylcarbamoyladenylate synthase
A3772_19870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A3772_19890	COG2890	protein-(glutamine-N5) methyltransferase activity
A3772_19895	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A3772_19900	COG0346	lactoylglutathione lyase activity
A3772_19905	COG0789	Transcriptional regulator
A3772_19910	COG0679	Auxin Efflux Carrier
A3772_19915	COG0281	malic enzyme
A3772_19920	COG1435	thymidine kinase activity
A3772_19925	COG0254	rRNA binding
A3772_19930	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A3772_19940	COG1494	fructose-1,6-bisphosphatase
A3772_19945	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A3772_19950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A3772_19955	COG0191	fructose-bisphosphate aldolase activity
A3772_19960	COG2204	response regulator
A3772_19965	COG4821	SIS domain
A3772_19970	COG0504	CTP synthase activity
A3772_19975	COG3343	RNA polymerase activity
A3772_19980	COG1960	acyl-CoA dehydrogenase activity
A3772_19985	COG0247	lactate metabolic process
A3772_19985	COG2181	nitrate reductase activity
A3772_19990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A3772_19995	COG4294	response to UV
A3772_20005	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A3772_20010	COG1132	(ABC) transporter
A3772_20015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A3772_20025	COG2181	nitrate reductase activity
A3772_20030	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A3772_20035	COG1140	nitrate reductase beta subunit
A3772_20040	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A3772_20045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3772_20055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3772_20060	COG2223	nitrite transmembrane transporter activity
A3772_20065	COG0018	arginyl-trna synthetase
A3772_20070	COG4506	Protein conserved in bacteria
A3772_20080	COG0535	radical SAM domain protein
A3772_20090	COG1131	(ABC) transporter
A3772_20095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A3772_20100	COG0612	Peptidase, M16
A3772_20105	COG0612	Peptidase, M16
A3772_20115	COG3391	amine dehydrogenase activity
A3772_20120	COG3391	amine dehydrogenase activity
A3772_20130	COG0457	Tetratricopeptide repeat
A3772_20140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A3772_20145	COG0010	Belongs to the arginase family
A3772_20150	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A3772_20155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3772_20165	COG1994	Peptidase M50
A3772_20170	COG1942	4-Oxalocrotonate Tautomerase
A3772_20175	COG1846	Transcriptional regulator
A3772_20180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3772_20190	COG0477	Major facilitator Superfamily
A3772_20195	COG1959	2 iron, 2 sulfur cluster binding
A3772_20200	COG3465	dGTPase activity
A3772_20205	COG1078	dGTPase activity
A3772_20210	COG4844	belongs to the
A3772_20220	COG0697	spore germination
A3772_20225	COG0095	Lipoate-protein ligase
A3772_20230	COG0583	DNA-binding transcription factor activity
A3772_20235	COG0280	phosphate acetyltransferase
A3772_20245	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_20250	COG0436	Aminotransferase
A3772_20255	COG2814	Major facilitator Superfamily
A3772_20260	COG0151	Belongs to the GarS family
A3772_20265	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_20270	COG1917	Cupin 2, conserved barrel domain protein
A3772_20275	COG0077	Prephenate dehydratase
A3772_20280	COG2814	Major facilitator Superfamily
A3772_20285	COG0833	amino acid
A3772_20290	COG4187	Peptidase family M20/M25/M40
A3772_20295	COG1012	belongs to the aldehyde dehydrogenase family
A3772_20300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3772_20310	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
A3772_20315	COG1091	dTDP-4-dehydrorhamnose reductase activity
A3772_20320	COG1088	dTDP-glucose 4,6-dehydratase activity
A3772_20325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A3772_20330	COG3980	spore coat polysaccharide biosynthesis protein
A3772_20335	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
A3772_20340	COG2089	acid synthase
A3772_20345	COG0456	acetyltransferase
A3772_20350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A3772_20355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A3772_20360	COG0463	Glycosyl transferase, family 2
A3772_20375	COG2363	Small membrane protein
A3772_20380	COG2233	PERMEase
A3772_20390	COG1012	belongs to the aldehyde dehydrogenase family
A3772_20395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A3772_20400	COG1216	Glycosyl transferase, family 2
A3772_20415	COG1695	Transcriptional regulator
A3772_20420	COG0351	phosphomethylpyrimidine kinase
A3772_20430	COG1621	beta-fructofuranosidase activity
A3772_20435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3772_20435	COG1263	PTS System
A3772_20440	COG2116	formate transmembrane transporter activity
A3772_20445	COG3711	transcriptional antiterminator
A3772_20455	COG1404	Belongs to the peptidase S8 family
A3772_20460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3772_20465	COG0778	Nitroreductase
A3772_20470	COG0772	Belongs to the SEDS family
A3772_20480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A3772_20485	COG1845	cytochrome c oxidase, subunit III
A3772_20490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A3772_20495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A3772_20500	COG2261	transglycosylase associated protein
A3772_20505	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A3772_20510	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3772_20515	COG2246	polysaccharide biosynthetic process
A3772_20520	COG1309	transcriptional regulator
A3772_20530	COG3162	membrane
A3772_20535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3772_20540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A3772_20545	COG2837	iron assimilation
A3772_20550	COG2822	iron ion transport
A3772_20555	COG0672	)-iron permease
A3772_20560	COG0352	thiamine-phosphate diphosphorylase activity
A3772_20565	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A3772_20570	COG0583	DNA-binding transcription factor activity
A3772_20575	COG1380	Effector of murein hydrolase LrgA
A3772_20580	COG1346	cytolysis
A3772_20585	COG2814	Major facilitator Superfamily
A3772_20590	COG4895	conserved protein (DUF2196)
A3772_20595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3772_20600	COG0346	lactoylglutathione lyase activity
A3772_20610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3772_20615	COG1404	Belongs to the peptidase S8 family
A3772_20620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3772_20620	COG1263	PTS System
A3772_20625	COG3711	transcriptional antiterminator
A3772_20630	COG1442	glycosyl transferase family 8
A3772_20635	COG5522	Integral membrane protein (intg_mem_TP0381)
A3772_20640	COG1846	Transcriptional regulator
A3772_20645	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A3772_20650	COG2234	aminopeptidase activity
A3772_20655	COG2357	RelA SpoT domain protein
A3772_20660	COG1575	Belongs to the MenA family. Type 1 subfamily
A3772_20675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3772_20680	COG1696	Membrane protein involved in D-alanine export
A3772_20685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3772_20690	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A3772_20695	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
A3772_20700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3772_20705	COG1486	melibiose metabolic process
A3772_20710	COG1447	Phosphotransferase system cellobiose-specific component IIA
A3772_20715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3772_20720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3772_20725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3772_20725	COG3711	transcriptional antiterminator
A3772_20735	COG2094	Belongs to the DNA glycosylase MPG family
A3772_20740	COG0753	catalase activity
A3772_20745	COG2814	Major facilitator Superfamily
A3772_20750	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A3772_20755	COG1131	(ABC) transporter
A3772_20775	COG1595	DNA-templated transcription, initiation
A3772_20780	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A3772_20785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A3772_20790	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A3772_20795	COG4988	ABC transporter
A3772_20800	COG1294	oxidase, subunit
A3772_20805	COG1271	oxidase subunit
A3772_20810	COG3493	citrate carrier protein
A3772_20815	COG0501	Belongs to the peptidase M48B family
A3772_20825	COG0726	polysaccharide deacetylase
A3772_20830	COG3842	ATPase activity
A3772_20835	COG2508	Transcriptional regulator
A3772_20840	COG1012	belongs to the aldehyde dehydrogenase family
A3772_20845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3772_20855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3772_20860	COG1881	PFAM PEBP family protein
A3772_20865	COG0583	DNA-binding transcription factor activity
A3772_20875	COG4585	Histidine kinase
A3772_20880	COG2197	response regulator
A3772_20885	COG2195	Cleaves the N-terminal amino acid of tripeptides
A3772_20900	COG4894	glucomannan catabolic process
A3772_20905	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A3772_20910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A3772_20915	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_20920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A3772_20925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A3772_20930	COG2610	gluconate transmembrane transporter activity
A3772_20940	COG0500	methyltransferase
A3772_20945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A3772_20965	COG0753	catalase activity
A3772_20965	COG0693	protein deglycase activity
A3772_20970	COG2851	Citrate transporter
A3772_20975	COG2273	Hydrolase Family 16
A3772_20980	COG3711	transcriptional antiterminator
A3772_20990	COG2270	Major facilitator Superfamily
A3772_20995	COG0513	Belongs to the DEAD box helicase family
A3772_21000	COG2755	lipolytic protein G-D-S-L family
A3772_21000	COG3401	FG-GAP repeat protein
A3772_21055	COG3209	COG3209 Rhs family protein
A3772_21060	COG0697	spore germination
A3772_21065	COG0589	response to stress
A3772_21070	COG2723	6-phospho-beta-galactosidase activity
A3772_21075	COG2190	(PTS) system
A3772_21075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3772_21075	COG1263	PTS System
A3772_21090	COG5444	nuclease activity
A3772_21105	COG3507	Belongs to the glycosyl hydrolase 43 family
A3772_21120	COG2986	histidine ammonia-lyase
A3772_21125	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
A3772_21130	COG1228	amidohydrolase
A3772_21135	COG0010	Belongs to the arginase family
A3772_21140	COG0833	amino acid
A3772_21145	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A3772_21150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A3772_21155	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A3772_21160	COG2390	Transcriptional regulator
A3772_21170	COG3192	ethanolamine utilization protein
A3772_21175	COG2079	MmgE PrpD family protein
A3772_21185	COG1126	abc transporter atp-binding protein
A3772_21190	COG0765	amino acid transport
A3772_21195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3772_21215	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A3772_21220	COG0561	phosphatase activity
A3772_21250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3772_21255	COG5294	Protein conserved in bacteria
A3772_21260	COG0577	efflux transmembrane transporter activity
A3772_21265	COG1136	(ABC) transporter
A3772_21270	COG2205	protein histidine kinase activity
A3772_21275	COG0745	RESPONSE REGULATOR receiver
A3772_21280	COG0191	fructose-bisphosphate aldolase activity
A3772_21285	COG1082	Xylose isomerase domain protein TIM barrel
A3772_21290	COG1082	Xylose isomerase domain protein TIM barrel
A3772_21295	COG0673	inositol 2-dehydrogenase activity
A3772_21300	COG2814	Major facilitator Superfamily
A3772_21305	COG1082	Xylose isomerase domain protein TIM barrel
A3772_21310	COG3962	Belongs to the TPP enzyme family
A3772_21315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3772_21320	COG3718	enzyme involved in inositol metabolism
A3772_21325	COG1012	belongs to the aldehyde dehydrogenase family
A3772_21330	COG1349	DNA-binding transcription factor activity
A3772_21335	COG0667	Aldo Keto reductase
A3772_21350	COG2814	Major facilitator Superfamily
A3772_21355	COG0326	Molecular chaperone. Has ATPase activity
A3772_21365	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_21370	COG1309	transcriptional regulator
A3772_21375	COG1012	belongs to the aldehyde dehydrogenase family
A3772_21380	COG0456	acetyltransferase
A3772_21385	COG2850	peptidyl-arginine hydroxylation
A3772_21390	COG2226	methyltransferase
A3772_21405	COG0367	asparagine synthase
A3772_21410	COG2814	Major facilitator Superfamily
A3772_21415	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A3772_21425	COG1714	RDD family
A3772_21430	COG2311	Membrane
A3772_21435	COG1917	Cupin 2, conserved barrel domain protein
A3772_21440	COG1309	transcriptional regulator
A3772_21445	COG1028	Short-chain dehydrogenase reductase Sdr
A3772_21450	COG1846	Transcriptional regulator
A3772_21455	COG1380	Effector of murein hydrolase LrgA
A3772_21460	COG1346	cytolysis
A3772_21465	COG5039	Polysaccharide pyruvyl transferase
A3772_21470	COG1929	Belongs to the glycerate kinase type-1 family
A3772_21475	COG1802	Transcriptional regulator
A3772_21480	COG1070	Carbohydrate kinase
A3772_21485	COG2610	gluconate transmembrane transporter activity
A3772_21490	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A3772_21495	COG0450	alkyl hydroperoxide reductase
A3772_21500	COG3634	alkyl hydroperoxide reductase activity
A3772_21505	COG2723	6-phospho-beta-galactosidase activity
A3772_21510	COG2190	(PTS) system
A3772_21515	COG2188	Transcriptional regulator
A3772_21530	COG1131	(ABC) transporter
A3772_21535	COG1994	Peptidase M50
A3772_21540	COG0535	radical SAM domain protein
A3772_21550	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
A3772_21555	COG5293	efflux transmembrane transporter activity
A3772_21565	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A3772_21570	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A3772_21580	COG1063	alcohol dehydrogenase
A3772_21600	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
A3772_21605	COG0456	acetyltransferase
A3772_21610	COG0457	Tetratricopeptide repeat
A3772_21620	COG0010	Belongs to the arginase family
A3772_21625	COG0833	amino acid
A3772_21630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A3772_21635	COG3829	transcription factor binding
A3772_21640	COG5002	protein histidine kinase activity
A3772_21650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3772_21655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A3772_21660	COG4853	Protein conserved in bacteria
A3772_21665	COG4863	YycH protein
A3772_21670	COG5002	protein histidine kinase activity
A3772_21675	COG0745	RESPONSE REGULATOR receiver
A3772_21705	COG0346	lactoylglutathione lyase activity
A3772_21710	COG0305	Participates in initiation and elongation during chromosome replication
A3772_21730	COG3093	addiction module antidote protein HigA
A3772_21735	COG2807	transmembrane transport
A3772_21740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3772_21745	COG0359	binds to the 23S rRNA
A3772_21750	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A3772_21755	COG4241	membrane
A3772_21765	COG5577	PFAM Coat F domain
A3772_21770	COG1733	regulation of RNA biosynthetic process
A3772_21775	COG1227	inorganic diphosphatase activity
A3772_21790	COG2271	Major facilitator Superfamily
A3772_21800	COG4319	ketosteroid isomerase
A3772_21830	COG1131	(ABC) transporter
A3772_21840	COG4319	ketosteroid isomerase
A3772_21845	COG1357	PFAM Pentapeptide repeats (8 copies)
A3772_21850	COG2814	Major facilitator Superfamily
A3772_21855	COG0583	DNA-binding transcription factor activity
A3772_21860	COG2153	protein acetylation
A3772_21870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3772_21875	COG1846	Transcriptional regulator
A3772_21880	COG2153	protein acetylation
A3772_21885	COG2364	Membrane
A3772_21890	COG0456	acetyltransferase
A3772_21895	COG2315	Protein conserved in bacteria
A3772_21900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A3772_21905	COG2814	Major facilitator Superfamily
A3772_21910	COG1331	Highly conserved protein containing a thioredoxin domain
A3772_21915	COG0789	Transcriptional regulator
A3772_21920	COG0697	spore germination
A3772_21925	COG1331	Highly conserved protein containing a thioredoxin domain
A3772_21930	COG1266	CAAX protease self-immunity
A3772_21935	COG2814	Major facilitator Superfamily
A3772_21935	COG0477	Major facilitator Superfamily
A3772_21940	COG0110	maltose O-acetyltransferase activity
A3772_21945	COG0346	lactoylglutathione lyase activity
A3772_21950	COG1609	Transcriptional regulator
A3772_21955	COG0708	Exodeoxyribonuclease III
A3772_21960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A3772_21965	COG0629	single-stranded DNA binding
A3772_21970	COG0360	Binds together with S18 to 16S ribosomal RNA
A3772_21975	COG0012	GTP binding
A3772_21980	COG0243	molybdopterin cofactor binding
A3772_21985	COG4481	Protein conserved in bacteria
A3772_21990	COG3949	Membrane
A3772_22000	COG1475	DNA binding
A3772_22005	COG1192	Involved in chromosome partitioning
A3772_22015	COG1475	DNA binding
A3772_22020	COG0357	Ribosomal RNA small subunit methyltransferase G
A3772_22025	COG0445	tRNA wobble uridine modification
A3772_22030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A3772_22035	COG1847	R3H domain protein
A3772_22040	COG0706	membrane insertase activity
A3772_22045	COG0594	ribonuclease P activity
A3772_22050	COG0230	Belongs to the bacterial ribosomal protein bL34 family