locus-tag	class	description
G4G26_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G4G26_00010	COG0592	DNA-directed DNA polymerase activity
G4G26_00015	COG2501	S4 domain
G4G26_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G4G26_00030	COG0187	DNA topoisomerase II activity
G4G26_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G4G26_00070	COG0517	IMP dehydrogenase activity
G4G26_00070	COG0516	GMP reductase activity
G4G26_00075	COG1686	Belongs to the peptidase S11 family
G4G26_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
G4G26_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G4G26_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G4G26_00100	COG1428	Deoxynucleoside kinase
G4G26_00105	COG1428	Deoxynucleoside kinase
G4G26_00110	COG3858	chitin binding
G4G26_00110	COG1388	LysM domain
G4G26_00115	COG1335	isochorismatase
G4G26_00120	COG0590	tRNA wobble adenosine to inosine editing
G4G26_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G4G26_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G4G26_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G4G26_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
G4G26_00190	COG3853	Toxic anion resistance protein (TelA)
G4G26_00195	COG1982	Orn Lys Arg decarboxylase major
G4G26_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G4G26_00205	COG3870	Protein conserved in bacteria
G4G26_00210	COG1728	Protein conserved in bacteria
G4G26_00215	COG0470	DNA polymerase III
G4G26_00220	COG1774	PSP1 C-terminal conserved region
G4G26_00225	COG4467	Involved in initiation control of chromosome replication
G4G26_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G4G26_00235	COG2827	Endonuclease containing a URI domain
G4G26_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G4G26_00245	COG2002	toxin-antitoxin pair type II binding
G4G26_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4G26_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4G26_00255	COG0084	hydrolase, TatD family'
G4G26_00260	COG3584	3D domain protein
G4G26_00260	COG3583	domain protein
G4G26_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G4G26_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G4G26_00280	COG4466	Protein conserved in bacteria
G4G26_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G4G26_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G4G26_00300	COG0251	oxidation-reduction process
G4G26_00305	COG2088	sporulation resulting in formation of a cellular spore
G4G26_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G4G26_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G4G26_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G4G26_00325	COG0193	aminoacyl-tRNA hydrolase activity
G4G26_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G4G26_00340	COG2002	toxin-antitoxin pair type II binding
G4G26_00345	COG2244	polysaccharide biosynthetic process
G4G26_00350	COG3956	TIGRFAM MazG family protein
G4G26_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G4G26_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G4G26_00375	COG1098	S1 RNA binding domain
G4G26_00390	COG2208	phosphoserine phosphatase activity
G4G26_00395	COG2304	oxidoreductase activity
G4G26_00400	COG0515	serine threonine protein kinase
G4G26_00405	COG0037	tRNA processing
G4G26_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G4G26_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G4G26_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G4G26_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4G26_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4G26_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G4G26_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
G4G26_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4G26_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G4G26_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G4G26_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G4G26_00470	COG1396	sequence-specific DNA binding
G4G26_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G4G26_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G4G26_00560	COG4463	regulation of RNA biosynthetic process
G4G26_00565	COG3880	PFAM UvrB UvrC protein
G4G26_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
G4G26_00575	COG0542	response to heat
G4G26_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G4G26_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G4G26_00590	COG4956	integral membrane protein (PIN domain superfamily)
G4G26_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G4G26_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G4G26_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G4G26_00610	COG1045	serine acetyltransferase
G4G26_00615	COG0215	cysteine-tRNA ligase activity
G4G26_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
G4G26_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4G26_00630	COG3688	RNA-binding protein containing a PIN domain
G4G26_00635	COG1595	DNA-templated transcription, initiation
G4G26_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G4G26_00650	COG0250	Participates in transcription elongation, termination and antitermination
G4G26_00660	COG0081	regulation of translation
G4G26_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G4G26_00675	COG2813	Specifically methylates the guanine in position
G4G26_00680	COG0085	RNA polymerase activity
G4G26_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G4G26_00690	COG1358	cellular component organization or biogenesis
G4G26_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G4G26_00700	COG0049	tRNA binding
G4G26_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G4G26_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G4G26_00715	COG0596	Alpha beta hydrolase
G4G26_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G4G26_00730	COG0088	Forms part of the polypeptide exit tunnel
G4G26_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G4G26_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G4G26_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G4G26_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G4G26_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G4G26_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G4G26_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G4G26_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G4G26_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G4G26_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G4G26_00820	COG0200	Binds to the 23S rRNA
G4G26_00825	COG0201	protein transport
G4G26_00830	COG0563	adenylate kinase activity
G4G26_00835	COG0024	Methionine aminopeptidase
G4G26_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
G4G26_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G4G26_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G4G26_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G4G26_00865	COG0202	RNA polymerase activity
G4G26_00870	COG0203	ribosomal protein L17
G4G26_00875	COG1122	ATPase activity
G4G26_00880	COG1122	ATPase activity
G4G26_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G4G26_00890	COG0101	tRNA pseudouridine synthase activity
G4G26_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G4G26_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G4G26_00905	COG2226	methyltransferase
G4G26_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4G26_00920	COG0489	protein tyrosine kinase activity
G4G26_00930	COG2194	sulfuric ester hydrolase activity
G4G26_00935	COG0726	polysaccharide deacetylase
G4G26_01020	COG0659	secondary active sulfate transmembrane transporter activity
G4G26_01025	COG0385	Bile acid
G4G26_01030	COG2819	hydrolase of the alpha beta superfamily
G4G26_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G26_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G26_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4G26_01050	COG2207	Transcriptional regulator
G4G26_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4G26_01055	COG3876	Protein conserved in bacteria
G4G26_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
G4G26_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4G26_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4G26_01070	COG1263	PTS System
G4G26_01075	COG1737	Transcriptional regulator
G4G26_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G4G26_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4G26_01120	COG1595	DNA-templated transcription, initiation
G4G26_01125	COG5662	AntiSigma factor
G4G26_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
G4G26_01135	COG4856	YbbR-like protein
G4G26_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G4G26_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G4G26_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G4G26_01160	COG2169	Transcriptional regulator
G4G26_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G4G26_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G4G26_01175	COG3002	Belongs to the UPF0753 family
G4G26_01180	COG0288	reversible hydration of carbon dioxide
G4G26_01190	COG5609	conserved protein (DUF2294)
G4G26_01195	COG0640	Transcriptional regulator
G4G26_01200	COG2814	Major facilitator Superfamily
G4G26_01215	COG1404	Belongs to the peptidase S8 family
G4G26_01235	COG1132	(ABC) transporter
G4G26_01240	COG0596	Alpha beta hydrolase
G4G26_01250	COG0642	Histidine kinase
G4G26_01260	COG0515	serine threonine protein kinase
G4G26_01275	COG1113	amino acid transport
G4G26_01290	COG2602	Beta-lactamase
G4G26_01295	COG2124	cytochrome p450
G4G26_01305	COG0531	amino acid
G4G26_01310	COG0584	glycerophosphoryl diester phosphodiesterase
G4G26_01315	COG2271	Major facilitator Superfamily
G4G26_01325	COG1846	Transcriptional regulator
G4G26_01325	COG0456	acetyltransferase
G4G26_01330	COG2271	Major facilitator Superfamily
G4G26_01340	COG3409	Peptidoglycan-binding domain 1 protein
G4G26_01345	COG0697	spore germination
G4G26_01350	COG1917	Cupin 2, conserved barrel domain protein
G4G26_01350	COG2207	Transcriptional regulator
G4G26_01355	COG1397	ADP-ribosylglycohydrolase
G4G26_01360	COG5444	nuclease activity
G4G26_01365	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G4G26_01370	COG3591	Belongs to the peptidase S1B family
G4G26_01380	COG0596	Alpha beta hydrolase
G4G26_01385	COG1183	phosphatidylcholine synthase activity
G4G26_01390	COG0586	Pfam SNARE associated Golgi protein
G4G26_01395	COG0688	phosphatidylethanolamine metabolic process
G4G26_01405	COG2312	Erythromycin esterase
G4G26_01415	COG1301	dicarboxylic acid transport
G4G26_01420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4G26_01420	COG1263	PTS System
G4G26_01420	COG2190	(PTS) system
G4G26_01425	COG0363	glucosamine-6-phosphate deaminase activity
G4G26_01430	COG2188	Transcriptional regulator
G4G26_01440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4G26_01445	COG0833	amino acid
G4G26_01450	COG2040	homocysteine
G4G26_01460	COG1115	amino acid carrier protein
G4G26_01465	COG2066	Belongs to the glutaminase family
G4G26_01470	COG4191	Histidine kinase
G4G26_01475	COG0784	Response regulator, receiver
G4G26_01480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G4G26_01485	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_01490	COG2271	Major facilitator Superfamily
G4G26_01495	COG4948	Mandelate Racemase Muconate Lactonizing
G4G26_01500	COG2186	Transcriptional regulator
G4G26_01505	COG2721	sulfolactate sulfo-lyase activity
G4G26_01510	COG3173	Aminoglycoside phosphotransferase
G4G26_01520	COG0697	spore germination
G4G26_01525	COG0745	RESPONSE REGULATOR receiver
G4G26_01530	COG2205	protein histidine kinase activity
G4G26_01535	COG1131	(ABC) transporter
G4G26_01555	COG3773	Cell wall hydrolase
G4G26_01560	COG2304	oxidoreductase activity
G4G26_01570	COG3540	Alkaline phosphatase
G4G26_01575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G4G26_01580	COG0805	protein transport
G4G26_01585	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
G4G26_01590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4G26_01595	COG0477	Major facilitator Superfamily
G4G26_01600	COG1309	transcriptional regulator
G4G26_01605	COG0252	asparaginase activity
G4G26_01610	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G4G26_01615	COG1714	RDD family
G4G26_01620	COG1405	negative regulation of cell septum assembly
G4G26_01620	COG3012	SEC-C Motif Domain Protein
G4G26_01625	COG3290	protein histidine kinase activity
G4G26_01630	COG3279	Response regulator of the LytR AlgR family
G4G26_01635	COG4555	ABC transporter
G4G26_01640	COG1668	transmembrane transport
G4G26_01645	COG0667	Aldo Keto reductase
G4G26_01660	COG1595	DNA-templated transcription, initiation
G4G26_01665	COG1595	DNA-templated transcription, initiation
G4G26_01670	COG1876	peptidase activity
G4G26_01675	COG0457	Tetratricopeptide repeat
G4G26_01680	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_01685	COG0366	Alpha amylase catalytic
G4G26_01690	COG0803	Belongs to the bacterial solute-binding protein 9 family
G4G26_01695	COG1121	(ABC) transporter
G4G26_01700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4G26_01705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G26_01710	COG2310	stress, protein
G4G26_01715	COG2310	stress, protein
G4G26_01720	COG2310	stress, protein
G4G26_01725	COG0861	Integral membrane protein TerC family
G4G26_01735	COG3853	Toxic anion resistance protein (TelA)
G4G26_01740	COG0477	Major facilitator Superfamily
G4G26_01750	COG0640	Transcriptional regulator
G4G26_01755	COG4175	Glycine betaine
G4G26_01755	COG0517	IMP dehydrogenase activity
G4G26_01760	COG4176	ABC-type proline glycine betaine transport system permease component
G4G26_01765	COG2113	Glycine betaine
G4G26_01770	COG1473	amidohydrolase
G4G26_01775	COG1288	antiporter activity
G4G26_01785	COG0366	Alpha amylase catalytic
G4G26_01790	COG0039	L-malate dehydrogenase activity
G4G26_01795	COG1620	l-lactate permease
G4G26_01800	COG2814	Major facilitator Superfamily
G4G26_01805	COG1846	Transcriptional regulator
G4G26_01810	COG1280	lysine exporter protein (LysE YggA)
G4G26_01815	COG3403	YqcI/YcgG family
G4G26_01820	COG1113	amino acid transport
G4G26_01825	COG3665	Urea carboxylase-associated protein
G4G26_01830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G4G26_01835	COG1660	Displays ATPase and GTPase activities
G4G26_01840	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G4G26_01845	COG2226	methyltransferase
G4G26_01850	COG0583	DNA-binding transcription factor activity
G4G26_01855	COG3458	cephalosporin-C deacetylase activity
G4G26_01860	COG3541	Predicted nucleotidyltransferase
G4G26_01865	COG0506	proline dehydrogenase activity
G4G26_01870	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_01875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4G26_01880	COG2508	Transcriptional regulator
G4G26_01885	COG3689	TIGRFAM TIGR03943 family protein
G4G26_01890	COG0701	Predicted permease
G4G26_01895	COG2267	carboxylic ester hydrolase activity
G4G26_01900	COG0492	ferredoxin-NADP+ reductase activity
G4G26_01905	COG1587	Uroporphyrinogen-III synthase
G4G26_01905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G4G26_01910	COG2146	nitrite reductase [NAD(P)H] activity
G4G26_01915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4G26_01920	COG0243	molybdopterin cofactor binding
G4G26_01925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4G26_01930	COG2223	nitrite transmembrane transporter activity
G4G26_01935	COG1469	GTP cyclohydrolase I activity
G4G26_01940	COG1376	ErfK ybiS ycfS ynhG family protein
G4G26_01950	COG0523	cobalamin synthesis protein
G4G26_01955	COG0765	amino acid transport
G4G26_01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G26_01980	COG2723	6-phospho-beta-galactosidase activity
G4G26_01990	COG3209	COG3209 Rhs family protein
G4G26_01995	COG0840	transmembrane signaling receptor activity
G4G26_01995	COG3290	protein histidine kinase activity
G4G26_02000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G4G26_02005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
G4G26_02010	COG1733	regulation of RNA biosynthetic process
G4G26_02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_02030	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G4G26_02035	COG2814	Major facilitator Superfamily
G4G26_02045	COG0697	spore germination
G4G26_02060	COG2364	Membrane
G4G26_02065	COG1126	abc transporter atp-binding protein
G4G26_02070	COG0765	amino acid transport
G4G26_02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G26_02080	COG0583	DNA-binding transcription factor activity
G4G26_02085	COG0163	prenyltransferase activity
G4G26_02090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G4G26_02105	COG0596	Alpha beta hydrolase
G4G26_02110	COG3104	oligopeptide transport
G4G26_02115	COG5434	Belongs to the glycosyl hydrolase 28 family
G4G26_02125	COG0697	spore germination
G4G26_02135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4G26_02140	COG1136	(ABC) transporter
G4G26_02145	COG0577	efflux transmembrane transporter activity
G4G26_02150	COG0745	RESPONSE REGULATOR receiver
G4G26_02155	COG5002	protein histidine kinase activity
G4G26_02155	COG3850	Histidine kinase
G4G26_02160	COG0457	Tetratricopeptide repeat
G4G26_02180	COG0527	aspartate kinase activity
G4G26_02185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G26_02190	COG4605	iron ion homeostasis
G4G26_02195	COG4604	ABC transporter, ATP-binding protein
G4G26_02200	COG4607	ABC-type enterochelin transport system periplasmic component
G4G26_02205	COG2814	Major facilitator Superfamily
G4G26_02210	COG1309	transcriptional regulator
G4G26_02215	COG0778	Nitroreductase
G4G26_02220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G4G26_02225	COG0640	Transcriptional regulator
G4G26_02230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G26_02235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G4G26_02240	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_02245	COG4975	Glucose uptake
G4G26_02250	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_02255	COG4549	nuclear export factor GLE1
G4G26_02260	COG1276	copper resistance
G4G26_02260	COG2372	response to copper ion
G4G26_02265	COG1349	DNA-binding transcription factor activity
G4G26_02275	COG2213	PTS system mannitol-specific
G4G26_02280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4G26_02285	COG0246	Mannitol dehydrogenase
G4G26_02290	COG0473	3-isopropylmalate dehydrogenase activity
G4G26_02295	COG0681	Belongs to the peptidase S26 family
G4G26_02300	COG0412	Dienelactone hydrolase
G4G26_02305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G4G26_02315	COG0561	phosphatase activity
G4G26_02320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G4G26_02325	COG1914	H( )-stimulated, divalent metal cation uptake system
G4G26_02330	COG4336	lyase activity
G4G26_02335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G4G26_02340	COG1984	allophanate hydrolase subunit 2
G4G26_02345	COG1414	Transcriptional regulator
G4G26_02350	COG2755	lipolytic protein G-D-S-L family
G4G26_02360	COG2329	Antibiotic biosynthesis monooxygenase
G4G26_02365	COG0768	penicillin binding
G4G26_02370	COG4989	oxidoreductase activity
G4G26_02375	COG3711	transcriptional antiterminator
G4G26_02380	COG0318	PFAM AMP-dependent synthetase and ligase
G4G26_02385	COG2226	methyltransferase
G4G26_02390	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_02395	COG1917	Cupin 2, conserved barrel domain protein
G4G26_02400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4G26_02405	COG3871	stress protein (general stress protein 26)
G4G26_02415	COG2814	Major facilitator Superfamily
G4G26_02420	COG1522	sequence-specific DNA binding
G4G26_02425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4G26_02425	COG0551	DNA topoisomerase type I activity
G4G26_02430	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
G4G26_02435	COG3706	GGDEF domain
G4G26_02440	COG5298	Protein conserved in bacteria
G4G26_02445	COG1215	transferase activity, transferring glycosyl groups
G4G26_02455	COG0531	amino acid
G4G26_02460	COG0494	nUDIX hydrolase
G4G26_02465	COG0028	Belongs to the TPP enzyme family
G4G26_02480	COG1914	H( )-stimulated, divalent metal cation uptake system
G4G26_02485	COG2261	transglycosylase associated protein
G4G26_02490	COG4876	unkown
G4G26_02495	COG2217	Heavy metal translocating P-type atpase
G4G26_02500	COG3729	General stress protein
G4G26_02505	COG0662	Cupin 2, conserved barrel domain protein
G4G26_02510	COG2329	Antibiotic biosynthesis monooxygenase
G4G26_02515	COG3546	catalase activity
G4G26_02520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G4G26_02525	COG3290	protein histidine kinase activity
G4G26_02530	COG4565	transcriptional regulatory protein
G4G26_02535	COG1301	dicarboxylic acid transport
G4G26_02540	COG0628	permease
G4G26_02545	COG1131	(ABC) transporter
G4G26_02550	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G4G26_02560	COG1960	acyl-CoA dehydrogenase activity
G4G26_02575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G4G26_02580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G26_02585	COG1181	Belongs to the D-alanine--D-alanine ligase family
G4G26_02590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G4G26_02595	COG0513	Belongs to the DEAD box helicase family
G4G26_02600	COG3402	PFAM membrane-flanked domain
G4G26_02605	COG3428	Bacterial PH domain
G4G26_02610	COG0705	Rhomboid family
G4G26_02615	COG0736	holo-[acyl-carrier-protein] synthase activity
G4G26_02620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G4G26_02625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G4G26_02630	COG0864	Transcriptional regulator
G4G26_02635	COG2337	Toxic component of a toxin-antitoxin (TA) module
G4G26_02640	COG1366	Belongs to the anti-sigma-factor antagonist family
G4G26_02645	COG1366	Belongs to the anti-sigma-factor antagonist family
G4G26_02650	COG2172	sigma factor antagonist activity
G4G26_02655	COG2208	phosphoserine phosphatase activity
G4G26_02660	COG1366	Belongs to the anti-sigma-factor antagonist family
G4G26_02665	COG2172	sigma factor antagonist activity
G4G26_02670	COG1191	sigma factor activity
G4G26_02675	COG2208	phosphoserine phosphatase activity
G4G26_02680	COG2183	response to ionizing radiation
G4G26_02690	COG3091	SprT-like family
G4G26_02740	COG1476	TRANSCRIPTIONal
G4G26_02765	COG0693	protein deglycase activity
G4G26_02770	COG1278	Cold shock
G4G26_02775	COG1329	Transcriptional regulator
G4G26_02780	COG0697	spore germination
G4G26_02785	COG2207	Transcriptional regulator
G4G26_02785	COG1917	Cupin 2, conserved barrel domain protein
G4G26_02790	COG0697	spore germination
G4G26_02795	COG3708	Transcriptional regulator
G4G26_02795	COG2207	Transcriptional regulator
G4G26_02800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G26_02805	COG0477	Major facilitator Superfamily
G4G26_02815	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
G4G26_02825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4G26_02830	COG1309	transcriptional regulator
G4G26_02835	COG0697	spore germination
G4G26_02840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G26_02845	COG2030	dehydratase
G4G26_02850	COG3545	Serine hydrolase
G4G26_02855	COG1733	regulation of RNA biosynthetic process
G4G26_02860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4G26_02865	COG2814	Major facilitator Superfamily
G4G26_02870	COG1309	transcriptional regulator
G4G26_02880	COG0640	Transcriptional regulator
G4G26_02885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G4G26_02895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4G26_02900	COG0697	spore germination
G4G26_02905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G26_02910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G4G26_02915	COG0640	Transcriptional regulator
G4G26_02920	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4G26_02935	COG4585	Histidine kinase
G4G26_02940	COG2197	response regulator
G4G26_02945	COG2409	Drug exporters of the RND superfamily
G4G26_02950	COG0596	Alpha beta hydrolase
G4G26_02955	COG1811	Na channel or pump
G4G26_02960	COG0789	Transcriptional regulator
G4G26_02960	COG4978	Transcriptional regulator
G4G26_02965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G4G26_02970	COG0778	Nitroreductase
G4G26_02975	COG0346	lactoylglutathione lyase activity
G4G26_02980	COG2259	Doxx family
G4G26_02985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G26_03005	COG2323	membrane
G4G26_03010	COG2323	membrane
G4G26_03015	COG0071	Belongs to the small heat shock protein (HSP20) family
G4G26_03030	COG1309	transcriptional regulator
G4G26_03040	COG0456	acetyltransferase
G4G26_03050	COG1113	amino acid transport
G4G26_03055	COG2318	DinB family
G4G26_03060	COG1846	Transcriptional regulator
G4G26_03065	COG2409	Drug exporters of the RND superfamily
G4G26_03065	COG1033	growth of symbiont in host cell
G4G26_03070	COG0778	Nitroreductase
G4G26_03075	COG1846	Transcriptional regulator
G4G26_03080	COG2814	Major facilitator Superfamily
G4G26_03085	COG0730	response to heat
G4G26_03090	COG1802	Transcriptional regulator
G4G26_03095	COG3858	chitin binding
G4G26_03095	COG1388	LysM domain
G4G26_03100	COG1819	glycosyl
G4G26_03110	COG1785	Belongs to the alkaline phosphatase family
G4G26_03115	COG5646	InterPro IPR014922
G4G26_03125	COG0454	-acetyltransferase
G4G26_03130	COG1078	dGTPase activity
G4G26_03135	COG1388	LysM domain
G4G26_03140	COG2814	Major facilitator Superfamily
G4G26_03145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4G26_03150	COG1447	Phosphotransferase system cellobiose-specific component IIA
G4G26_03155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4G26_03160	COG2723	6-phospho-beta-galactosidase activity
G4G26_03165	COG2188	Transcriptional regulator
G4G26_03170	COG1940	carbohydrate kinase activity
G4G26_03175	COG1482	cell wall glycoprotein biosynthetic process
G4G26_03180	COG4124	Belongs to the glycosyl hydrolase 26 family
G4G26_03225	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G4G26_03230	COG0802	atpase or kinase
G4G26_03235	COG1214	PFAM Peptidase M22, glycoprotease
G4G26_03240	COG0456	acetyltransferase
G4G26_03245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G4G26_03250	COG0488	(ABC) transporter
G4G26_03255	COG0315	cyclic pyranopterin monophosphate synthase activity
G4G26_03260	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
G4G26_03265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G4G26_03270	COG0805	protein transport
G4G26_03280	COG1266	CAAX protease self-immunity
G4G26_03290	COG0459	protein refolding
G4G26_03300	COG1073	alpha beta
G4G26_03305	COG0457	Tetratricopeptide repeat
G4G26_03310	COG1063	alcohol dehydrogenase
G4G26_03315	COG2211	Major facilitator Superfamily
G4G26_03320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4G26_03325	COG1842	Phage shock protein A
G4G26_03330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G4G26_03335	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G4G26_03340	COG4260	virion core protein, lumpy skin disease virus
G4G26_03350	COG2814	Major facilitator Superfamily
G4G26_03355	COG1063	alcohol dehydrogenase
G4G26_03360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G4G26_03365	COG0823	Involved in the tonB-independent uptake of proteins
G4G26_03380	COG2267	carboxylic ester hydrolase activity
G4G26_03390	COG2132	Multicopper oxidase
G4G26_03395	COG1113	amino acid transport
G4G26_03405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G4G26_03410	COG0714	Associated with various cellular activities
G4G26_03415	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
G4G26_03420	COG1305	Transglutaminase-like
G4G26_03425	COG0519	Catalyzes the synthesis of GMP from XMP
G4G26_03425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G4G26_03440	COG2252	PERMEase
G4G26_03445	COG3064	Membrane
G4G26_03455	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
G4G26_03465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G4G26_03470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G4G26_03475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G4G26_03480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G4G26_03485	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G4G26_03490	COG0047	phosphoribosylformylglycinamidine synthase activity
G4G26_03495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G4G26_03500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G4G26_03505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G4G26_03510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G4G26_03515	COG0138	bifunctional purine biosynthesis protein purh
G4G26_03520	COG0151	Belongs to the GarS family
G4G26_03525	COG1522	sequence-specific DNA binding
G4G26_03530	COG0531	amino acid
G4G26_03540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G4G26_03545	COG1470	cell adhesion involved in biofilm formation
G4G26_03550	COG4496	protein, YerC YecD
G4G26_03555	COG0069	glutamate synthase activity
G4G26_03560	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
G4G26_03565	COG0210	DNA helicase
G4G26_03570	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G4G26_03575	COG4851	CamS sex pheromone cAM373 precursor
G4G26_03580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4G26_03585	COG1285	pathogenesis
G4G26_03590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4G26_03595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G4G26_03600	COG0154	amidase activity
G4G26_03605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G4G26_03610	COG1309	transcriptional regulator
G4G26_03615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G4G26_03620	COG1597	lipid kinase activity
G4G26_03625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G4G26_03635	COG0457	Tetratricopeptide repeat
G4G26_03650	COG5444	nuclease activity
G4G26_03655	COG3391	amine dehydrogenase activity
G4G26_03665	COG0457	Tetratricopeptide repeat
G4G26_03675	COG0217	transcriptional regulatory protein
G4G26_03685	COG1309	transcriptional regulator
G4G26_03690	COG3631	Ketosteroid isomerase-related protein
G4G26_03695	COG0702	epimerase
G4G26_03710	COG3546	catalase activity
G4G26_03715	COG0454	-acetyltransferase
G4G26_03725	COG5578	integral membrane protein
G4G26_03730	COG2972	Histidine kinase
G4G26_03735	COG4753	response regulator
G4G26_03735	COG2207	Transcriptional regulator
G4G26_03740	COG1653	transport
G4G26_03745	COG1175	transmembrane transport
G4G26_03750	COG0395	ABC-type sugar transport system, permease component
G4G26_03755	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
G4G26_03760	COG2207	Transcriptional regulator
G4G26_03765	COG2755	lipolytic protein G-D-S-L family
G4G26_03775	COG5578	integral membrane protein
G4G26_03780	COG3401	FG-GAP repeat protein
G4G26_03785	COG3401	FG-GAP repeat protein
G4G26_03790	COG2755	lipolytic protein G-D-S-L family
G4G26_03795	COG1874	Beta-galactosidase
G4G26_03805	COG1653	transport
G4G26_03810	COG4209	transmembrane transport
G4G26_03815	COG0395	ABC-type sugar transport system, permease component
G4G26_03820	COG1486	melibiose metabolic process
G4G26_03825	COG2323	membrane
G4G26_03830	COG2329	Antibiotic biosynthesis monooxygenase
G4G26_03835	COG0346	lactoylglutathione lyase activity
G4G26_03850	COG5583	Uncharacterized small protein (DUF2292)
G4G26_03855	COG0670	Belongs to the BI1 family
G4G26_03860	COG0697	spore germination
G4G26_03865	COG1846	Transcriptional regulator
G4G26_03870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G4G26_03885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G4G26_03885	COG2124	cytochrome p450
G4G26_03890	COG1368	sulfuric ester hydrolase activity
G4G26_03895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G4G26_03900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4G26_03905	COG1442	glycosyl transferase family 8
G4G26_03910	COG1216	Glycosyl transferase, family 2
G4G26_03915	COG1442	glycosyl transferase family 8
G4G26_03920	COG2223	nitrite transmembrane transporter activity
G4G26_03925	COG1011	Hydrolase
G4G26_03930	COG0531	amino acid
G4G26_03935	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_03940	COG0840	transmembrane signaling receptor activity
G4G26_03945	COG0488	(ABC) transporter
G4G26_03955	COG0789	Transcriptional regulator
G4G26_03960	COG2814	Major facilitator Superfamily
G4G26_03970	COG0488	(ABC) transporter
G4G26_03975	COG0513	Belongs to the DEAD box helicase family
G4G26_03980	COG0456	acetyltransferase
G4G26_03985	COG2130	NADP-dependent
G4G26_03990	COG2211	Major facilitator Superfamily
G4G26_03995	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G4G26_04000	COG1120	ATPase activity
G4G26_04005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G26_04010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G26_04015	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G4G26_04030	COG3866	Pectate lyase
G4G26_04035	COG0471	metal ion transport
G4G26_04040	COG3290	protein histidine kinase activity
G4G26_04045	COG4565	transcriptional regulatory protein
G4G26_04050	COG3181	Tripartite tricarboxylate transporter family receptor
G4G26_04055	COG2851	Citrate transporter
G4G26_04060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G26_04065	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
G4G26_04070	COG1254	Belongs to the acylphosphatase family
G4G26_04075	COG2258	MOSC domain
G4G26_04095	COG0024	Methionine aminopeptidase
G4G26_04100	COG1263	PTS System
G4G26_04100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4G26_04105	COG1368	sulfuric ester hydrolase activity
G4G26_04120	COG1115	amino acid carrier protein
G4G26_04125	COG0531	amino acid
G4G26_04145	COG1263	PTS System
G4G26_04145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4G26_04150	COG0366	Alpha amylase catalytic
G4G26_04155	COG2188	Transcriptional regulator
G4G26_04160	COG0778	Nitroreductase
G4G26_04165	COG0737	Belongs to the 5'-nucleotidase family
G4G26_04170	COG0693	protein deglycase activity
G4G26_04175	COG2814	Major facilitator Superfamily
G4G26_04180	COG4840	Belongs to the UPF0435 family
G4G26_04185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4G26_04190	COG4980	gas vesicle protein
G4G26_04195	COG1295	ribonuclease BN
G4G26_04200	COG0477	Major facilitator Superfamily
G4G26_04205	COG0387	Pfam Sodium calcium exchanger
G4G26_04215	COG0668	transmembrane transport
G4G26_04220	COG0535	radical SAM domain protein
G4G26_04230	COG0726	polysaccharide deacetylase
G4G26_04235	COG2084	Dehydrogenase
G4G26_04240	COG0598	Magnesium transport protein CorA
G4G26_04245	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G4G26_04250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G4G26_04260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G4G26_04265	COG4637	Psort location Cytoplasmic, score
G4G26_04270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4G26_04275	COG0022	dehydrogenase e1 component
G4G26_04280	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4G26_04285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4G26_04290	COG3284	Transcriptional regulator
G4G26_04300	COG1742	UPF0060 membrane protein
G4G26_04320	COG4842	Belongs to the WXG100 family
G4G26_04325	COG1486	melibiose metabolic process
G4G26_04330	COG1737	Transcriptional regulator
G4G26_04335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4G26_04335	COG1263	PTS System
G4G26_04340	COG1132	(ABC) transporter
G4G26_04345	COG1132	(ABC) transporter
G4G26_04350	COG2259	Doxx family
G4G26_04355	COG2514	catechol 2,3-dioxygenase activity
G4G26_04360	COG4585	Histidine kinase
G4G26_04365	COG2197	response regulator
G4G26_04370	COG1131	(ABC) transporter
G4G26_04375	COG0842	Transport permease protein
G4G26_04375	COG1511	domain protein
G4G26_04380	COG0842	Transport permease protein
G4G26_04385	COG1695	Transcriptional regulator
G4G26_04390	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G4G26_04395	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
G4G26_04400	COG2318	DinB family
G4G26_04405	COG2814	Major facilitator Superfamily
G4G26_04410	COG1846	Transcriptional regulator
G4G26_04415	COG0392	lysyltransferase activity
G4G26_04415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G4G26_04420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4G26_04425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G26_04430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G26_04435	COG0384	phenazine biosynthesis protein PhzF
G4G26_04440	COG0778	Nitroreductase
G4G26_04455	COG1090	epimerase
G4G26_04460	COG2137	regulation of response to DNA damage stimulus
G4G26_04470	COG2814	Major facilitator Superfamily
G4G26_04485	COG3103	Sh3 type 3 domain protein
G4G26_04490	COG5658	integral membrane protein
G4G26_04495	COG0596	Alpha beta hydrolase
G4G26_04500	COG0463	Glycosyl transferase, family 2
G4G26_04505	COG4485	Bacterial membrane protein, YfhO
G4G26_04510	COG1988	membrane-bound metal-dependent
G4G26_04515	COG1194	a g-specific adenine glycosylase
G4G26_04525	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_04540	COG3557	Belongs to the UPF0374 family
G4G26_04545	COG1132	(ABC) transporter
G4G26_04550	COG4129	membrane
G4G26_04555	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G4G26_04560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G4G26_04565	COG0735	belongs to the Fur family
G4G26_04675	COG4326	sporulation control protein
G4G26_04685	COG5577	PFAM Coat F domain
G4G26_04690	COG3340	Belongs to the peptidase S51 family
G4G26_04695	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G4G26_04700	COG0277	FAD linked oxidase domain protein
G4G26_04710	COG0753	catalase activity
G4G26_04715	COG1116	anion transmembrane transporter activity
G4G26_04720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G26_04725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G26_04730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G26_04740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G4G26_04750	COG1476	TRANSCRIPTIONal
G4G26_04760	COG3382	B3 4 domain protein
G4G26_04765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G4G26_04775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G4G26_04780	COG0789	Transcriptional regulator
G4G26_04785	COG1664	Polymer-forming cytoskeletal
G4G26_04790	COG1664	Polymer-forming cytoskeletal
G4G26_04795	COG2766	serine protein kinase
G4G26_04800	COG2718	Belongs to the UPF0229 family
G4G26_04805	COG1846	Transcriptional regulator
G4G26_04810	COG1566	PFAM secretion protein HlyD family protein
G4G26_04815	COG2814	Major facilitator Superfamily
G4G26_04820	COG0655	NAD(P)H dehydrogenase (quinone) activity
G4G26_04840	COG1725	Transcriptional regulator
G4G26_04845	COG1131	(ABC) transporter
G4G26_04850	COG1131	(ABC) transporter
G4G26_04855	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G4G26_04860	COG1278	Cold shock
G4G26_04865	COG1464	Belongs to the NlpA lipoprotein family
G4G26_04870	COG3706	GGDEF domain
G4G26_04875	COG1823	symporter activity
G4G26_04895	COG5577	PFAM Coat F domain
G4G26_04900	COG1525	nuclease
G4G26_04900	COG4085	toxin activity
G4G26_04900	COG0737	Belongs to the 5'-nucleotidase family
G4G26_04905	COG3764	Sortase (surface protein transpeptidase)
G4G26_04910	COG0564	pseudouridine synthase activity
G4G26_04920	COG0517	IMP dehydrogenase activity
G4G26_04925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G4G26_04930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4G26_04930	COG3153	acetyltransferase
G4G26_04935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4G26_04940	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
G4G26_04945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G4G26_04950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G4G26_04955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G4G26_04960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G4G26_04965	COG4585	Histidine kinase
G4G26_04965	COG2203	Gaf domain
G4G26_04970	COG2197	response regulator
G4G26_04975	COG0431	NADPH-dependent FMN reductase
G4G26_04990	COG1388	LysM domain
G4G26_04990	COG0791	NLP P60 protein
G4G26_04995	COG1959	2 iron, 2 sulfur cluster binding
G4G26_05000	COG0668	transmembrane transport
G4G26_05005	COG2719	SpoVR family
G4G26_05010	COG1785	Belongs to the alkaline phosphatase family
G4G26_05015	COG1388	LysM domain
G4G26_05015	COG0791	NLP P60 protein
G4G26_05020	COG0583	DNA-binding transcription factor activity
G4G26_05025	COG0372	Belongs to the citrate synthase family
G4G26_05030	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_05035	COG0531	amino acid
G4G26_05040	COG0733	neurotransmitter:sodium symporter activity
G4G26_05045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G26_05050	COG0456	acetyltransferase
G4G26_05065	COG1595	DNA-templated transcription, initiation
G4G26_05070	COG0667	Aldo Keto reductase
G4G26_05075	COG0204	Acyl-transferase
G4G26_05080	COG1253	flavin adenine dinucleotide binding
G4G26_05085	COG0789	Transcriptional regulator
G4G26_05090	COG0436	Aminotransferase
G4G26_05095	COG1253	flavin adenine dinucleotide binding
G4G26_05100	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G4G26_05105	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G4G26_05110	COG0584	glycerophosphoryl diester phosphodiesterase
G4G26_05120	COG0668	transmembrane transport
G4G26_05125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G4G26_05130	COG0726	polysaccharide deacetylase
G4G26_05135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4G26_05140	COG1757	Na H antiporter
G4G26_05145	COG0589	response to stress
G4G26_05155	COG1132	(ABC) transporter
G4G26_05160	COG1132	(ABC) transporter
G4G26_05165	COG0702	epimerase
G4G26_05185	COG0189	ligase activity
G4G26_05190	COG0189	ligase activity
G4G26_05195	COG4399	Belongs to the UPF0754 family
G4G26_05200	COG3679	Belongs to the UPF0342 family
G4G26_05205	COG4335	DNA alkylation repair
G4G26_05210	COG0561	phosphatase activity
G4G26_05215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G4G26_05220	COG0475	glutathione-regulated potassium exporter activity
G4G26_05225	COG0490	domain, Protein
G4G26_05235	COG1024	Enoyl-CoA hydratase
G4G26_05245	COG4152	abc transporter atp-binding protein
G4G26_05250	COG1668	transmembrane transport
G4G26_05255	COG0420	3'-5' exonuclease activity
G4G26_05260	COG4717	serine-type aminopeptidase activity
G4G26_05265	COG3481	metal-dependent phosphohydrolase, HD sub domain
G4G26_05275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4G26_05305	COG1846	Transcriptional regulator
G4G26_05310	COG4980	gas vesicle protein
G4G26_05325	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G4G26_05330	COG0537	adenosine 5'-monophosphoramidase activity
G4G26_05335	COG1131	(ABC) transporter
G4G26_05340	COG4473	ABC transporter
G4G26_05350	COG1473	amidohydrolase
G4G26_05355	COG3069	C4-dicarboxylate transmembrane transporter activity
G4G26_05365	COG2329	Antibiotic biosynthesis monooxygenase
G4G26_05370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4G26_05375	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G4G26_05390	COG1309	transcriptional regulator
G4G26_05395	COG1511	domain protein
G4G26_05400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4G26_05405	COG4377	Putative membrane peptidase family (DUF2324)
G4G26_05415	COG1363	Peptidase, m42
G4G26_05420	COG4405	Protein conserved in bacteria
G4G26_05425	COG1301	dicarboxylic acid transport
G4G26_05435	COG1234	tRNA 3'-trailer cleavage
G4G26_05440	COG0095	Lipoate-protein ligase
G4G26_05445	COG0702	epimerase
G4G26_05450	COG0318	PFAM AMP-dependent synthetase and ligase
G4G26_05460	COG0501	Belongs to the peptidase M48B family
G4G26_05470	COG0456	acetyltransferase
G4G26_05475	COG0604	alcohol dehydrogenase
G4G26_05480	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G4G26_05485	COG0406	alpha-ribazole phosphatase activity
G4G26_05490	COG0183	Belongs to the thiolase family
G4G26_05495	COG0318	PFAM AMP-dependent synthetase and ligase
G4G26_05500	COG1268	BioY protein
G4G26_05505	COG0840	transmembrane signaling receptor activity
G4G26_05510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G26_05510	COG0723	plastoquinol--plastocyanin reductase activity
G4G26_05515	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_05525	COG4903	ComK protein
G4G26_05530	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_05540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4G26_05555	COG0398	Pfam SNARE associated Golgi protein
G4G26_05560	COG0681	Belongs to the peptidase S26 family
G4G26_05565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G4G26_05570	COG1846	Transcriptional regulator
G4G26_05580	COG0738	Major facilitator superfamily
G4G26_05585	COG0673	inositol 2-dehydrogenase activity
G4G26_05590	COG0561	phosphatase activity
G4G26_05595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4G26_05600	COG1609	Transcriptional regulator
G4G26_05605	COG3180	Ammonia monooxygenase
G4G26_05610	COG0477	Major facilitator Superfamily
G4G26_05610	COG2814	Major facilitator Superfamily
G4G26_05615	COG4533	DNA binding
G4G26_05625	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
G4G26_05630	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
G4G26_05635	COG1074	ATP-dependent DNA helicase activity
G4G26_05640	COG0420	3'-5' exonuclease activity
G4G26_05645	COG0419	ATPase involved in DNA repair
G4G26_05650	COG1403	HNH endonuclease
G4G26_05690	COG5337	Spore coat protein CotH
G4G26_05695	COG0179	Fumarylacetoacetate (FAA) hydrolase
G4G26_05705	COG1404	Belongs to the peptidase S8 family
G4G26_05715	COG0367	asparagine synthase
G4G26_05720	COG2318	DinB family
G4G26_05725	COG1562	ergosterol biosynthetic process
G4G26_05730	COG0534	Mate efflux family protein
G4G26_05735	COG1917	Cupin 2, conserved barrel domain protein
G4G26_05735	COG2207	Transcriptional regulator
G4G26_05740	COG1609	Transcriptional regulator
G4G26_05745	COG0673	inositol 2-dehydrogenase activity
G4G26_05750	COG2318	DinB family
G4G26_05755	COG1279	arginine transmembrane transporter activity
G4G26_05760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G26_05765	COG1357	PFAM Pentapeptide repeats (8 copies)
G4G26_05770	COG2267	carboxylic ester hydrolase activity
G4G26_05775	COG0529	Catalyzes the synthesis of activated sulfate
G4G26_05780	COG2046	Belongs to the sulfate adenylyltransferase family
G4G26_05785	COG0175	sulfate reduction
G4G26_05790	COG2045	Belongs to the ComB family
G4G26_05795	COG1809	phosphosulfolactate synthase activity
G4G26_05800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4G26_05805	COG4948	Mandelate Racemase Muconate Lactonizing
G4G26_05810	COG2814	Major facilitator Superfamily
G4G26_05815	COG0454	-acetyltransferase
G4G26_05820	COG2153	protein acetylation
G4G26_05825	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G4G26_05825	COG0646	methionine synthase
G4G26_05830	COG1666	GTP binding
G4G26_05835	COG2996	Protein conserved in bacteria
G4G26_05855	COG1695	Transcriptional regulator
G4G26_05870	COG3227	Zinc metalloprotease (Elastase)
G4G26_05875	COG1307	EDD domain protein, DegV family
G4G26_05880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4G26_05900	COG0561	phosphatase activity
G4G26_05905	COG1073	alpha beta
G4G26_05910	COG2151	metal-sulfur cluster biosynthetic enzyme
G4G26_05920	COG0277	FAD linked oxidase domain protein
G4G26_05925	COG2271	Major facilitator Superfamily
G4G26_05930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G4G26_05935	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G4G26_05945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G4G26_05950	COG0505	Belongs to the CarA family
G4G26_05955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G4G26_05960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G4G26_05975	COG2267	carboxylic ester hydrolase activity
G4G26_05985	COG1744	ABC transporter substrate-binding protein PnrA-like
G4G26_06000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4G26_06005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4G26_06010	COG5504	Zn-dependent protease
G4G26_06015	COG0444	Belongs to the ABC transporter superfamily
G4G26_06020	COG4608	Belongs to the ABC transporter superfamily
G4G26_06030	COG0601	transmembrane transport
G4G26_06035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4G26_06045	COG0180	Tryptophanyl-tRNA synthetase
G4G26_06050	COG4166	transmembrane transport
G4G26_06055	COG0601	transmembrane transport
G4G26_06060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4G26_06065	COG0444	Belongs to the ABC transporter superfamily
G4G26_06070	COG4608	Belongs to the ABC transporter superfamily
G4G26_06075	COG2814	Major facilitator Superfamily
G4G26_06080	COG0456	acetyltransferase
G4G26_06085	COG1393	Belongs to the ArsC family
G4G26_06090	COG0861	Integral membrane protein TerC family
G4G26_06100	COG4862	establishment of competence for transformation
G4G26_06110	COG4469	Competence protein
G4G26_06115	COG1164	Oligoendopeptidase f
G4G26_06130	COG2346	COG2346, Truncated hemoglobins
G4G26_06135	COG0741	lytic transglycosylase activity
G4G26_06140	COG4116	CYTH
G4G26_06150	COG2357	RelA SpoT domain protein
G4G26_06155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G4G26_06160	COG0564	pseudouridine synthase activity
G4G26_06165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G4G26_06170	COG0569	domain protein
G4G26_06170	COG0475	glutathione-regulated potassium exporter activity
G4G26_06175	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G4G26_06180	COG0352	thiamine-phosphate diphosphorylase activity
G4G26_06185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G26_06190	COG2104	thiamine diphosphate biosynthetic process
G4G26_06195	COG2022	thiamine diphosphate biosynthetic process
G4G26_06200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G4G26_06205	COG0351	phosphomethylpyrimidine kinase
G4G26_06210	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G4G26_06265	COG0210	DNA helicase
G4G26_06275	COG2153	protein acetylation
G4G26_06280	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G4G26_06285	COG2382	esterase
G4G26_06290	COG0626	cystathionine gamma-synthase activity
G4G26_06295	COG0626	cystathionine gamma-synthase activity
G4G26_06300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4G26_06305	COG5505	Protein of unknown function (DUF819)
G4G26_06325	COG5444	nuclease activity
G4G26_06375	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G4G26_06380	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_06390	COG3711	transcriptional antiterminator
G4G26_06390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4G26_06395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4G26_06395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4G26_06395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4G26_06400	COG1482	cell wall glycoprotein biosynthetic process
G4G26_06410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4G26_06420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G4G26_06435	COG0109	protoheme IX farnesyltransferase activity
G4G26_06445	COG0726	polysaccharide deacetylase
G4G26_06460	COG5504	Zn-dependent protease
G4G26_06465	COG2205	protein histidine kinase activity
G4G26_06475	COG3383	formate dehydrogenase (NAD+) activity
G4G26_06480	COG2427	Protein of unknown function (DUF1641)
G4G26_06490	COG1051	belongs to the nudix hydrolase family
G4G26_06500	COG2124	cytochrome p450
G4G26_06505	COG1819	glycosyl
G4G26_06515	COG1587	Uroporphyrinogen-III synthase
G4G26_06520	COG0390	transport system, permease component
G4G26_06525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4G26_06530	COG0697	spore germination
G4G26_06535	COG4297	protein containing double-stranded beta helix domain
G4G26_06545	COG1252	NADH dehydrogenase
G4G26_06550	COG1904	glucuronate isomerase
G4G26_06555	COG2211	Major facilitator Superfamily
G4G26_06560	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G4G26_06565	COG1063	alcohol dehydrogenase
G4G26_06570	COG1312	Catalyzes the dehydration of D-mannonate
G4G26_06575	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_06580	COG2271	Major facilitator Superfamily
G4G26_06585	COG1609	Transcriptional regulator
G4G26_06590	COG0246	Mannitol dehydrogenase
G4G26_06595	COG2721	sulfolactate sulfo-lyase activity
G4G26_06600	COG0730	response to heat
G4G26_06605	COG2318	DinB family
G4G26_06610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G4G26_06615	COG0457	Tetratricopeptide repeat
G4G26_06625	COG2350	Protein conserved in bacteria
G4G26_06630	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4G26_06630	COG1388	LysM domain
G4G26_06630	COG3409	Peptidoglycan-binding domain 1 protein
G4G26_06640	COG4195	phage-related replication protein
G4G26_06645	COG3546	catalase activity
G4G26_06650	COG2856	Zn peptidase
G4G26_06655	COG1396	sequence-specific DNA binding
G4G26_06665	COG1522	sequence-specific DNA binding
G4G26_06670	COG1484	DNA-dependent DNA replication
G4G26_06690	COG1595	DNA-templated transcription, initiation
G4G26_06695	COG3728	DNA packaging
G4G26_06695	COG5484	DNA packaging
G4G26_06700	COG1783	phage Terminase large subunit
G4G26_06705	COG5518	Phage portal protein
G4G26_06710	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G4G26_06715	COG4653	Phage capsid family
G4G26_06765	COG3953	SLT domain
G4G26_06765	COG5412	phage tail tape measure protein
G4G26_06765	COG3953	SLT domain
G4G26_06765	COG5412	phage tail tape measure protein
G4G26_06770	COG1652	LysM domain
G4G26_06775	COG4193	domain, Protein
G4G26_06785	COG3628	GPW Gp25 family protein
G4G26_06790	COG3299	homolog of phage Mu protein gp47
G4G26_06795	COG3778	Protein conserved in bacteria
G4G26_06835	COG3409	Peptidoglycan-binding domain 1 protein
G4G26_06835	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4G26_06855	COG0306	phosphate transporter
G4G26_06860	COG1392	Phosphate transport regulator
G4G26_06865	COG0531	amino acid
G4G26_06870	COG0346	lactoylglutathione lyase activity
G4G26_06880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G4G26_06885	COG0463	Glycosyl transferase, family 2
G4G26_06890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4G26_06895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G4G26_06900	COG2362	D-Aminopeptidase
G4G26_06905	COG0601	transmembrane transport
G4G26_06910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4G26_06915	COG0444	Belongs to the ABC transporter superfamily
G4G26_06920	COG4166	transmembrane transport
G4G26_06925	COG1619	proteins homologs of microcin C7 resistance protein MccF
G4G26_06930	COG4948	Mandelate Racemase Muconate Lactonizing
G4G26_06935	COG0791	NLP P60 protein
G4G26_06940	COG4608	Belongs to the ABC transporter superfamily
G4G26_06945	COG2706	6-phosphogluconolactonase activity
G4G26_06950	COG1834	amidinotransferase
G4G26_06955	COG1607	acyl-coa hydrolase
G4G26_06960	COG1017	nitric oxide dioxygenase activity
G4G26_06960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G4G26_06970	COG2323	membrane
G4G26_06975	COG2318	DinB family
G4G26_06980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4G26_06985	COG2076	Multidrug Resistance protein
G4G26_06990	COG2076	Multidrug Resistance protein
G4G26_06995	COG0788	formyltetrahydrofolate deformylase activity
G4G26_07000	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G4G26_07005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G4G26_07010	COG1764	response to oxidative stress
G4G26_07015	COG1846	Transcriptional regulator
G4G26_07020	COG1764	response to oxidative stress
G4G26_07030	COG0590	tRNA wobble adenosine to inosine editing
G4G26_07035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G4G26_07040	COG1404	Belongs to the peptidase S8 family
G4G26_07045	COG1366	Belongs to the anti-sigma-factor antagonist family
G4G26_07050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G4G26_07055	COG1122	ATPase activity
G4G26_07060	COG4721	ABC-type cobalt transport system, permease component
G4G26_07070	COG0745	RESPONSE REGULATOR receiver
G4G26_07075	COG3850	Histidine kinase
G4G26_07075	COG5002	protein histidine kinase activity
G4G26_07080	COG3212	peptidase
G4G26_07085	COG3212	peptidase
G4G26_07095	COG2239	Acts as a magnesium transporter
G4G26_07100	COG0789	Transcriptional regulator
G4G26_07115	COG1846	Transcriptional regulator
G4G26_07120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G4G26_07125	COG0726	polysaccharide deacetylase
G4G26_07130	COG1408	metallophosphoesterase
G4G26_07140	COG0463	Glycosyl transferase, family 2
G4G26_07145	COG1793	dna ligase
G4G26_07145	COG3285	dna ligase
G4G26_07150	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G4G26_07155	COG5001	Diguanylate cyclase
G4G26_07155	COG3300	MHYT domain
G4G26_07160	COG0586	Pfam SNARE associated Golgi protein
G4G26_07165	COG0861	Integral membrane protein TerC family
G4G26_07170	COG1191	sigma factor activity
G4G26_07190	COG0501	Belongs to the peptidase M48B family
G4G26_07195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G4G26_07210	COG3594	Acyltransferase
G4G26_07215	COG5002	protein histidine kinase activity
G4G26_07220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G4G26_07230	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G4G26_07235	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
G4G26_07240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4G26_07245	COG0436	Aminotransferase
G4G26_07250	COG1850	ribulose-bisphosphate carboxylase activity
G4G26_07255	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
G4G26_07260	COG0235	Class ii aldolase
G4G26_07265	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
G4G26_07270	COG3339	Conserved Protein
G4G26_07285	COG3852	Histidine kinase
G4G26_07290	COG1846	Transcriptional regulator
G4G26_07295	COG1360	Flagellar Motor Protein
G4G26_07300	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G4G26_07305	COG0542	response to heat
G4G26_07310	COG3949	Membrane
G4G26_07315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G4G26_07320	COG0720	synthase
G4G26_07325	COG0602	queuosine metabolic process
G4G26_07330	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G4G26_07335	COG1733	regulation of RNA biosynthetic process
G4G26_07340	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_07345	COG1388	LysM domain
G4G26_07345	COG4641	Protein conserved in bacteria
G4G26_07350	COG1388	LysM domain
G4G26_07355	COG3858	chitin binding
G4G26_07365	COG4873	Protein conserved in bacteria
G4G26_07375	COG3773	Cell wall hydrolase
G4G26_07380	COG2244	polysaccharide biosynthetic process
G4G26_07385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G26_07390	COG2217	Heavy metal translocating P-type atpase
G4G26_07400	COG0006	proline dipeptidase activity
G4G26_07405	COG1609	Transcriptional regulator
G4G26_07410	COG3711	transcriptional antiterminator
G4G26_07415	COG1263	PTS System
G4G26_07415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4G26_07415	COG2190	(PTS) system
G4G26_07420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4G26_07425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G4G26_07435	COG1533	DNA photolyase activity
G4G26_07440	COG0456	acetyltransferase
G4G26_07445	COG0840	transmembrane signaling receptor activity
G4G26_07450	COG2084	Dehydrogenase
G4G26_07455	COG2340	Cysteine-rich secretory protein family
G4G26_07460	COG0768	penicillin binding
G4G26_07465	COG4191	Histidine kinase
G4G26_07470	COG0436	Aminotransferase
G4G26_07480	COG0784	Response regulator, receiver
G4G26_07480	COG0835	chemotaxis
G4G26_07490	COG2814	Major facilitator Superfamily
G4G26_07495	COG1376	ErfK ybiS ycfS ynhG family protein
G4G26_07500	COG1408	metallophosphoesterase
G4G26_07505	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_07510	COG2200	EAL domain
G4G26_07515	COG4703	Protein of unknown function (DUF1797)
G4G26_07520	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
G4G26_07530	COG0517	IMP dehydrogenase activity
G4G26_07535	COG0583	DNA-binding transcription factor activity
G4G26_07540	COG0716	FMN binding
G4G26_07550	COG0716	FMN binding
G4G26_07555	COG2171	N-acyltransferase activity
G4G26_07560	COG1473	amidohydrolase
G4G26_07570	COG0668	transmembrane transport
G4G26_07575	COG0450	alkyl hydroperoxide reductase
G4G26_07580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G26_07595	COG0746	molybdenum cofactor guanylyltransferase activity
G4G26_07600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G4G26_07605	COG0303	'Molybdopterin
G4G26_07610	COG1763	Mo-molybdopterin cofactor biosynthetic process
G4G26_07615	COG0314	molybdopterin synthase activity
G4G26_07620	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G4G26_07625	COG1132	(ABC) transporter
G4G26_07630	COG1132	(ABC) transporter
G4G26_07640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G26_07645	COG1136	(ABC) transporter
G4G26_07650	COG0577	efflux transmembrane transporter activity
G4G26_07655	COG1349	DNA-binding transcription factor activity
G4G26_07660	COG1105	Belongs to the carbohydrate kinase PfkB family
G4G26_07665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4G26_07665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4G26_07665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4G26_07670	COG0681	Belongs to the peptidase S26 family
G4G26_07680	COG0488	(ABC) transporter
G4G26_07685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G4G26_07690	COG2309	aminopeptidase activity
G4G26_07700	COG1077	Cell shape determining protein MreB Mrl
G4G26_07705	COG2002	toxin-antitoxin pair type II binding
G4G26_07710	COG3852	Histidine kinase
G4G26_07715	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
G4G26_07715	COG2105	PFAM AIG2 family protein
G4G26_07720	COG0569	domain protein
G4G26_07725	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G4G26_07730	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G4G26_07740	COG0561	phosphatase activity
G4G26_07745	COG0242	peptide deformylase activity
G4G26_07755	COG0497	DNA recombination
G4G26_07760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4G26_07765	COG0022	dehydrogenase e1 component
G4G26_07770	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4G26_07775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4G26_07780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G26_07790	COG1982	Orn Lys Arg decarboxylase major
G4G26_07795	COG4476	Belongs to the UPF0223 family
G4G26_07800	COG4493	Belongs to the UPF0637 family
G4G26_07810	COG0483	inositol monophosphate 1-phosphatase activity
G4G26_07820	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G4G26_07840	COG1595	DNA-templated transcription, initiation
G4G26_07870	COG4896	Protein conserved in bacteria
G4G26_07880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G4G26_07885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G4G26_07890	COG2066	Belongs to the glutaminase family
G4G26_07895	COG4838	Belongs to the UPF0358 family
G4G26_07900	COG0772	Belongs to the SEDS family
G4G26_07905	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G4G26_07910	COG1612	heme a metabolic process
G4G26_07915	COG0109	protoheme IX farnesyltransferase activity
G4G26_07920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G4G26_07920	COG2010	Cytochrome c
G4G26_07925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G4G26_07930	COG1845	cytochrome c oxidase, subunit III
G4G26_07935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G4G26_07940	COG3336	cytochrome c oxidase
G4G26_07950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
G4G26_07955	COG2340	Cysteine-rich secretory protein family
G4G26_07970	COG3679	Belongs to the UPF0342 family
G4G26_07975	COG4471	UPF0298 protein
G4G26_07980	COG0742	ribosomal rna small subunit methyltransferase
G4G26_07985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G4G26_07990	COG3314	Sporulation integral membrane protein YlbJ
G4G26_07995	COG1752	Esterase of the alpha-beta hydrolase superfamily
G4G26_08000	COG3480	Lon protease (S16) C-terminal proteolytic domain
G4G26_08005	COG1323	Belongs to the UPF0348 family
G4G26_08015	COG1399	metal-binding, possibly nucleic acid-binding protein
G4G26_08030	COG0454	-acetyltransferase
G4G26_08035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G4G26_08040	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
G4G26_08045	COG2001	Belongs to the MraZ family
G4G26_08050	COG0275	rRNA processing
G4G26_08055	COG4839	cell division protein FtsL
G4G26_08065	COG0768	penicillin binding
G4G26_08070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G4G26_08075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G4G26_08080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G4G26_08085	COG0772	Belongs to the SEDS family
G4G26_08090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G4G26_08095	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G4G26_08100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G4G26_08105	COG3879	Bacterial protein of unknown function (DUF881)
G4G26_08110	COG3879	Bacterial protein of unknown function (DUF881)
G4G26_08115	COG3856	small basic protein
G4G26_08120	COG0849	cell division
G4G26_08125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G4G26_08130	COG4412	M6 family metalloprotease domain protein
G4G26_08130	COG1404	Belongs to the peptidase S8 family
G4G26_08140	COG1191	sigma factor activity
G4G26_08145	COG1191	sigma factor activity
G4G26_08150	COG1119	ATPase activity
G4G26_08155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4G26_08160	COG1873	PFAM PRC-barrel domain
G4G26_08170	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G4G26_08175	COG1799	cell septum assembly
G4G26_08180	COG0762	integral membrane protein
G4G26_08185	COG2302	S4 RNA-binding domain
G4G26_08190	COG3599	regulation of cell shape
G4G26_08195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G4G26_08200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4G26_08205	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G4G26_08210	COG0564	pseudouridine synthase activity
G4G26_08215	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G4G26_08220	COG2233	PERMEase
G4G26_08225	COG0540	Belongs to the ATCase OTCase family
G4G26_08230	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G4G26_08235	COG0505	Belongs to the CarA family
G4G26_08240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G4G26_08245	COG0543	2 iron, 2 sulfur cluster binding
G4G26_08250	COG0167	dihydroorotate dehydrogenase activity
G4G26_08255	COG0284	orotidine-5'-phosphate decarboxylase activity
G4G26_08260	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G4G26_08265	COG0175	sulfate reduction
G4G26_08270	COG0306	phosphate transporter
G4G26_08275	COG2046	Belongs to the sulfate adenylyltransferase family
G4G26_08280	COG0529	Catalyzes the synthesis of activated sulfate
G4G26_08285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G4G26_08290	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
G4G26_08295	COG1648	precorrin-2 dehydrogenase activity
G4G26_08300	COG1293	RNA-binding protein homologous to eukaryotic snRNP
G4G26_08305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G4G26_08310	COG1561	YicC-like family, N-terminal region
G4G26_08320	COG0194	GDP metabolic process
G4G26_08325	COG1758	RNA polymerase activity
G4G26_08330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G4G26_08335	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G4G26_08340	COG0242	peptide deformylase activity
G4G26_08345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G4G26_08350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G4G26_08350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G4G26_08355	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G4G26_08360	COG0631	protein serine/threonine phosphatase activity
G4G26_08365	COG2815	serine threonine protein kinase
G4G26_08365	COG0515	serine threonine protein kinase
G4G26_08370	COG1162	GTPase activity
G4G26_08375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G4G26_08380	COG1564	THIamine pyrophosphokinase
G4G26_08390	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G4G26_08395	COG1302	Protein conserved in bacteria
G4G26_08400	COG1461	Dihydroxyacetone kinase
G4G26_08405	COG1760	l-serine dehydratase
G4G26_08410	COG1760	l-serine dehydratase
G4G26_08415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G4G26_08420	COG1349	DNA-binding transcription factor activity
G4G26_08420	COG2050	protein possibly involved in aromatic compounds catabolism
G4G26_08425	COG0416	fatty acid biosynthetic process
G4G26_08430	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4G26_08435	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_08445	COG0571	ribonuclease III activity
G4G26_08450	COG1196	nuclear chromosome segregation
G4G26_08455	COG0552	protein localization to endoplasmic reticulum
G4G26_08465	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
G4G26_08470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G4G26_08475	COG0228	four-way junction DNA binding
G4G26_08480	COG1837	Belongs to the UPF0109 family
G4G26_08490	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G4G26_08495	COG0336	Belongs to the RNA methyltransferase TrmD family
G4G26_08500	COG0335	large ribosomal subunit rRNA binding
G4G26_08505	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G4G26_08510	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G4G26_08520	COG2257	FlhB HrpN YscU SpaS Family
G4G26_08525	COG0045	succinate-CoA ligase (ADP-forming) activity
G4G26_08530	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G4G26_08535	COG0758	DNA mediated transformation
G4G26_08540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4G26_08545	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
G4G26_08550	COG4974	Belongs to the 'phage' integrase family
G4G26_08555	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G4G26_08560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G4G26_08565	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G4G26_08570	COG1815	bacterial-type flagellum-dependent cell motility
G4G26_08575	COG1558	bacterial-type flagellum-dependent cell motility
G4G26_08580	COG1677	Flagellar hook-basal body complex protein FliE
G4G26_08585	COG1766	The M ring may be actively involved in energy transduction
G4G26_08590	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G4G26_08595	COG1317	bacterial-type flagellum organization
G4G26_08600	COG1157	protein secretion by the type III secretion system
G4G26_08605	COG2882	bacterial-type flagellum organization
G4G26_08610	COG3334	PFAM MgtE intracellular
G4G26_08615	COG3144	bacterial-type flagellum assembly
G4G26_08620	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G4G26_08625	COG4786	Flagellar basal body rod
G4G26_08630	COG1582	Flagellar protein (FlbD)
G4G26_08635	COG1580	Controls the rotational direction of flagella during chemotaxis
G4G26_08640	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G4G26_08645	COG1776	CheC inhibitor of MCP methylation
G4G26_08645	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G4G26_08650	COG2201	protein-glutamate methylesterase activity
G4G26_08655	COG3190	flagellar
G4G26_08660	COG1338	Plays a role in the flagellum-specific transport system
G4G26_08665	COG1987	bacterial-type flagellum assembly
G4G26_08670	COG1684	flagellar biosynthetic protein fliR
G4G26_08675	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G4G26_08680	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G4G26_08685	COG1419	protein localization to endoplasmic reticulum
G4G26_08690	COG0455	bacterial-type flagellum organization
G4G26_08695	COG2201	protein-glutamate methylesterase activity
G4G26_08700	COG2198	Histidine kinase
G4G26_08700	COG0643	Histidine kinase
G4G26_08705	COG0835	chemotaxis
G4G26_08710	COG1776	CheC inhibitor of MCP methylation
G4G26_08715	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G4G26_08720	COG1191	sigma factor activity
G4G26_08730	COG0052	Belongs to the universal ribosomal protein uS2 family
G4G26_08735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G4G26_08740	COG0528	UMP kinase activity
G4G26_08745	COG0233	cytoplasmic translational termination
G4G26_08750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G4G26_08755	COG4589	Belongs to the CDS family
G4G26_08760	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G4G26_08765	COG0750	zinc metalloprotease
G4G26_08770	COG0442	prolyl-tRNA aminoacylation
G4G26_08775	COG2176	DNA-directed DNA polymerase activity
G4G26_08780	COG0779	Required for maturation of 30S ribosomal subunits
G4G26_08785	COG0195	Participates in both transcription termination and antitermination
G4G26_08790	COG2740	Nucleic-acid-binding protein implicated in transcription termination
G4G26_08795	COG1358	cellular component organization or biogenesis
G4G26_08800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G4G26_08805	COG1550	Protein conserved in bacteria
G4G26_08810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G4G26_08815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G4G26_08820	COG0196	riboflavin kinase activity
G4G26_08825	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G4G26_08830	COG1185	polyribonucleotide nucleotidyltransferase activity
G4G26_08835	COG0726	polysaccharide deacetylase
G4G26_08840	COG0612	Peptidase, M16
G4G26_08845	COG1873	PFAM PRC-barrel domain
G4G26_08850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4G26_08855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G4G26_08860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G4G26_08865	COG0527	aspartate kinase activity
G4G26_08870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G4G26_08875	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G4G26_08880	COG0740	serine-type endopeptidase activity
G4G26_08890	COG1674	ftsk spoiiie
G4G26_08890	COG4980	gas vesicle protein
G4G26_08895	COG2188	Transcriptional regulator
G4G26_08900	COG2814	Major facilitator Superfamily
G4G26_08905	COG0612	Peptidase, M16
G4G26_08910	COG0612	Peptidase, M16
G4G26_08915	COG0300	oxidoreductase activity
G4G26_08930	COG1426	Protein conserved in bacteria
G4G26_08935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G4G26_08940	COG1058	Belongs to the CinA family
G4G26_08940	COG1546	Belongs to the CinA family
G4G26_08945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G4G26_08950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4G26_08955	COG1418	mRNA catabolic process
G4G26_08960	COG1692	metallophosphoesterase
G4G26_08965	COG2359	stage V sporulation protein S
G4G26_08970	COG1063	alcohol dehydrogenase
G4G26_08975	COG0156	8-amino-7-oxononanoate synthase activity
G4G26_08980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G4G26_08985	COG4550	Control of competence regulator ComK, YlbF/YmcA
G4G26_08995	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G4G26_09000	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G4G26_09015	COG3226	Transcriptional regulator
G4G26_09020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G26_09030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4G26_09035	COG3321	synthase
G4G26_09040	COG2070	2-Nitropropane dioxygenase
G4G26_09040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4G26_09045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4G26_09050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4G26_09055	COG3425	synthase
G4G26_09060	COG1024	Enoyl-CoA hydratase
G4G26_09065	COG1024	Enoyl-CoA hydratase
G4G26_09070	COG0300	oxidoreductase activity
G4G26_09070	COG0318	PFAM AMP-dependent synthetase and ligase
G4G26_09070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_09070	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_09070	COG3321	synthase
G4G26_09075	COG4221	oxidoreductase activity
G4G26_09075	COG0300	oxidoreductase activity
G4G26_09075	COG3321	synthase
G4G26_09075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4G26_09080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4G26_09080	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_09080	COG3321	synthase
G4G26_09080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4G26_09080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_09085	COG4221	oxidoreductase activity
G4G26_09085	COG3321	synthase
G4G26_09085	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_09085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_09090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4G26_09090	COG3321	synthase
G4G26_09090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G4G26_09090	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
G4G26_09095	COG2124	cytochrome p450
G4G26_09105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G26_09110	COG1404	Belongs to the peptidase S8 family
G4G26_09120	COG4195	phage-related replication protein
G4G26_09125	COG1764	response to oxidative stress
G4G26_09130	COG2076	Multidrug Resistance protein
G4G26_09135	COG2076	Multidrug Resistance protein
G4G26_09150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G4G26_09155	COG1923	regulation of RNA biosynthetic process
G4G26_09170	COG1780	Probably involved in ribonucleotide reductase function
G4G26_09175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4G26_09180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4G26_09185	COG4112	unkown
G4G26_09190	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4G26_09195	COG0464	growth
G4G26_09200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G4G26_09205	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
G4G26_09210	COG0789	Transcriptional regulator
G4G26_09215	COG0174	glutamine synthetase
G4G26_09230	COG1396	sequence-specific DNA binding
G4G26_09400	COG5280	Phage tail tape measure protein TP901
G4G26_09400	COG3953	SLT domain
G4G26_09410	COG1705	Flagellar rod assembly protein muramidase FlgJ
G4G26_09415	COG5434	Belongs to the glycosyl hydrolase 28 family
G4G26_09445	COG3409	Peptidoglycan-binding domain 1 protein
G4G26_09445	COG1388	LysM domain
G4G26_09445	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4G26_09455	COG5444	nuclease activity
G4G26_09460	COG0457	Tetratricopeptide repeat
G4G26_09500	COG0463	Glycosyl transferase, family 2
G4G26_09520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4G26_09535	COG3655	Transcriptional regulator
G4G26_09550	COG0135	phosphoribosylanthranilate isomerase activity
G4G26_09565	COG2211	Major facilitator Superfamily
G4G26_09570	COG3507	Belongs to the glycosyl hydrolase 43 family
G4G26_09575	COG1940	carbohydrate kinase activity
G4G26_09580	COG2115	Belongs to the xylose isomerase family
G4G26_09585	COG1070	Carbohydrate kinase
G4G26_09595	COG1525	nuclease
G4G26_09600	COG2814	Major facilitator Superfamily
G4G26_09605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G4G26_09615	COG0756	dUTP diphosphatase activity
G4G26_09655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G4G26_09665	COG3832	glyoxalase III activity
G4G26_09680	COG0531	amino acid
G4G26_09710	COG4195	phage-related replication protein
G4G26_09725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G4G26_09730	COG1388	LysM domain
G4G26_09735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G4G26_09740	COG4224	UPF0291 protein
G4G26_09745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G4G26_09755	COG3763	UPF0154 protein
G4G26_09765	COG0785	Cytochrome C biogenesis protein
G4G26_09770	COG2201	protein-glutamate methylesterase activity
G4G26_09775	COG4846	Membrane protein involved in cytochrome C biogenesis
G4G26_09785	COG0071	Belongs to the small heat shock protein (HSP20) family
G4G26_09800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G4G26_09805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G26_09825	COG0824	Thioesterase
G4G26_09835	COG4841	protein insertion into membrane
G4G26_09840	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G4G26_09845	COG1832	CoA-binding protein
G4G26_09850	COG0187	DNA topoisomerase II activity
G4G26_09855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G4G26_09865	COG1115	amino acid carrier protein
G4G26_09870	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G4G26_09880	COG5520	Belongs to the glycosyl hydrolase 30 family
G4G26_09885	COG3507	Belongs to the glycosyl hydrolase 43 family
G4G26_09890	COG2246	polysaccharide biosynthetic process
G4G26_09895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G4G26_09900	COG0586	Pfam SNARE associated Golgi protein
G4G26_09905	COG2404	hydrolase activity, acting on ester bonds
G4G26_09910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G4G26_09915	COG1024	Enoyl-CoA hydratase
G4G26_09920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G4G26_09925	COG0511	ligase activity, forming carbon-carbon bonds
G4G26_09930	COG0439	Biotin carboxylase
G4G26_09935	COG0318	PFAM AMP-dependent synthetase and ligase
G4G26_09940	COG1960	acyl-CoA dehydrogenase activity
G4G26_09955	COG1649	PFAM Uncharacterised BCR, COG1649
G4G26_09965	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
G4G26_09965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_09970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_09975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_09980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_09985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_09990	COG2027	D-alanyl-D-alanine carboxypeptidase
G4G26_09995	COG2017	converts alpha-aldose to the beta-anomer
G4G26_10000	COG0534	Mate efflux family protein
G4G26_10015	COG0582	viral genome integration into host DNA
G4G26_10020	COG0166	Belongs to the GPI family
G4G26_10025	COG0405	Gamma-glutamyltransferase
G4G26_10030	COG0583	DNA-binding transcription factor activity
G4G26_10035	COG0604	alcohol dehydrogenase
G4G26_10040	COG0493	'glutamate synthase
G4G26_10045	COG0067	glutamate synthase
G4G26_10045	COG0070	glutamate synthase
G4G26_10045	COG0069	glutamate synthase activity
G4G26_10050	COG0583	DNA-binding transcription factor activity
G4G26_10055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G4G26_10060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G4G26_10070	COG0300	oxidoreductase activity
G4G26_10075	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
G4G26_10090	COG2814	Major facilitator Superfamily
G4G26_10095	COG1070	Carbohydrate kinase
G4G26_10100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G4G26_10105	COG0243	molybdopterin cofactor binding
G4G26_10135	COG5278	phosphoserine phosphatase activity
G4G26_10135	COG0840	transmembrane signaling receptor activity
G4G26_10140	COG2368	4-hydroxyphenylacetate
G4G26_10145	COG4305	rare lipoprotein A
G4G26_10150	COG3619	membrane
G4G26_10155	COG3866	Pectate lyase
G4G26_10160	COG2135	peptidase activity
G4G26_10170	COG2140	Oxalate decarboxylase
G4G26_10180	COG0456	acetyltransferase
G4G26_10200	COG2720	vancomycin resistance protein
G4G26_10210	COG3655	Transcriptional regulator
G4G26_10215	COG3739	integral membrane protein
G4G26_10220	COG0583	DNA-binding transcription factor activity
G4G26_10225	COG0697	spore germination
G4G26_10235	COG0693	protein deglycase activity
G4G26_10240	COG2367	Beta-lactamase
G4G26_10260	COG3848	Pyruvate phosphate dikinase
G4G26_10260	COG0574	Belongs to the PEP-utilizing enzyme family
G4G26_10265	COG0726	polysaccharide deacetylase
G4G26_10270	COG2314	TM2 domain
G4G26_10300	COG4282	regulation of fungal-type cell wall biogenesis
G4G26_10305	COG1231	oxidoreductase activity
G4G26_10310	COG5434	Belongs to the glycosyl hydrolase 28 family
G4G26_10315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4G26_10320	COG2207	Transcriptional regulator
G4G26_10320	COG0662	Cupin 2, conserved barrel domain protein
G4G26_10325	COG0456	acetyltransferase
G4G26_10330	COG1309	transcriptional regulator
G4G26_10335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G26_10340	COG3708	Transcriptional regulator
G4G26_10345	COG2378	regulation of single-species biofilm formation
G4G26_10355	COG0640	Transcriptional regulator
G4G26_10360	COG0741	lytic transglycosylase activity
G4G26_10365	COG2322	membrane
G4G26_10380	COG1619	proteins homologs of microcin C7 resistance protein MccF
G4G26_10385	COG3239	Fatty acid desaturase
G4G26_10390	COG4585	Histidine kinase
G4G26_10395	COG2197	response regulator
G4G26_10400	COG1388	LysM domain
G4G26_10400	COG3584	3D domain protein
G4G26_10405	COG0514	ATP-dependent DNA helicase (RecQ)
G4G26_10415	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G4G26_10420	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4G26_10435	COG0071	Belongs to the small heat shock protein (HSP20) family
G4G26_10460	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_10465	COG1657	PFAM Prenyltransferase squalene oxidase
G4G26_10470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G4G26_10475	COG0733	neurotransmitter:sodium symporter activity
G4G26_10480	COG0385	Bile acid
G4G26_10485	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4G26_10490	COG0567	Dehydrogenase, E1 component
G4G26_10495	COG4548	von Willebrand factor, type A
G4G26_10500	COG0714	Associated with various cellular activities
G4G26_10505	COG2032	superoxide dismutase activity
G4G26_10510	COG1388	LysM domain
G4G26_10510	COG0791	NLP P60 protein
G4G26_10515	COG1819	glycosyl
G4G26_10520	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
G4G26_10525	COG0534	Mate efflux family protein
G4G26_10530	COG1366	Belongs to the anti-sigma-factor antagonist family
G4G26_10535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4G26_10540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4G26_10550	COG2962	Rard protein
G4G26_10565	COG2610	gluconate transmembrane transporter activity
G4G26_10570	COG1942	4-Oxalocrotonate Tautomerase
G4G26_10575	COG1733	regulation of RNA biosynthetic process
G4G26_10580	COG0778	Nitroreductase
G4G26_10585	COG0400	carboxylic ester hydrolase activity
G4G26_10590	COG0346	lactoylglutathione lyase activity
G4G26_10600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4G26_10605	COG0793	Belongs to the peptidase S41A family
G4G26_10605	COG3409	Peptidoglycan-binding domain 1 protein
G4G26_10610	COG2226	methyltransferase
G4G26_10620	COG1876	peptidase activity
G4G26_10625	COG0813	purine-nucleoside phosphorylase activity
G4G26_10640	COG0671	phosphoesterase, PA-phosphatase related
G4G26_10660	COG4479	Belongs to the UPF0346 family
G4G26_10670	COG1509	lysine 2,3-aminomutase activity
G4G26_10675	COG0456	acetyltransferase
G4G26_10680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4G26_10685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G4G26_10690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G4G26_10695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4G26_10710	COG0456	acetyltransferase
G4G26_10715	COG0463	Glycosyl transferase, family 2
G4G26_10730	COG4641	Protein conserved in bacteria
G4G26_10735	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
G4G26_10740	COG1086	Polysaccharide biosynthesis protein
G4G26_10745	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G4G26_10750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G4G26_10755	COG1846	Transcriptional regulator
G4G26_10760	COG0534	Mate efflux family protein
G4G26_10770	COG4698	Protein conserved in bacteria
G4G26_10775	COG2755	lipolytic protein G-D-S-L family
G4G26_10780	COG1999	signal sequence binding
G4G26_10790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G4G26_10795	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G4G26_10800	COG1272	protein, Hemolysin III
G4G26_10805	COG0204	Acyl-transferase
G4G26_10810	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G4G26_10815	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G4G26_10820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G4G26_10830	COG2136	Putative SAM-dependent methyltransferase
G4G26_10830	COG2521	methyltransferase
G4G26_10840	COG0129	dihydroxy-acid dehydratase activity
G4G26_10845	COG1413	lyase activity
G4G26_10850	COG1418	mRNA catabolic process
G4G26_10855	COG0386	Belongs to the glutathione peroxidase family
G4G26_10860	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G4G26_10865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G4G26_10875	COG1278	Cold shock
G4G26_10895	COG0328	RNA-DNA hybrid ribonuclease activity
G4G26_10900	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G4G26_10905	COG0328	RNA-DNA hybrid ribonuclease activity
G4G26_10915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4G26_10930	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G4G26_10940	COG1755	Isoprenylcysteine carboxyl methyltransferase
G4G26_10945	COG3424	synthase
G4G26_10950	COG2233	PERMEase
G4G26_10955	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G4G26_10960	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G4G26_10970	COG0800	Aldolase
G4G26_10975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4G26_10980	COG1609	Transcriptional regulator
G4G26_10985	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
G4G26_10990	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_10995	COG1199	ATP-dependent helicase activity
G4G26_11010	COG0116	Belongs to the methyltransferase superfamily
G4G26_11025	COG4474	Belongs to the UPF0398 family
G4G26_11040	COG3359	exonuclease
G4G26_11045	COG1205	dead DEAH box helicase
G4G26_11045	COG1111	helicase
G4G26_11050	COG2190	(PTS) system
G4G26_11055	COG0071	Belongs to the small heat shock protein (HSP20) family
G4G26_11090	COG3331	DNA recombination
G4G26_11095	COG4499	WXG100 protein secretion system (Wss), protein YukC
G4G26_11095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4G26_11105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G4G26_11110	COG3935	DnaD domain protein
G4G26_11115	COG0017	Asparaginyl-tRNA synthetase
G4G26_11120	COG0436	Aminotransferase
G4G26_11125	COG5353	protein conserved in bacteria
G4G26_11135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G4G26_11135	COG1199	ATP-dependent helicase activity
G4G26_11140	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G4G26_11145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G4G26_11150	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G4G26_11155	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G4G26_11155	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G4G26_11160	COG0617	tRNA 3'-terminal CCA addition
G4G26_11165	COG0438	transferase activity, transferring glycosyl groups
G4G26_11170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4G26_11175	COG1803	Methylglyoxal synthase
G4G26_11180	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G4G26_11185	COG1694	Mazg nucleotide pyrophosphohydrolase
G4G26_11190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4G26_11200	COG4347	Protein of unknown function (DUF1405)
G4G26_11205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G4G26_11205	COG2010	Cytochrome c
G4G26_11210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G4G26_11215	COG0723	plastoquinol--plastocyanin reductase activity
G4G26_11225	COG5582	Belongs to the UPF0302 family
G4G26_11230	COG0457	Tetratricopeptide repeat
G4G26_11235	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G4G26_11240	COG0287	Prephenate dehydrogenase
G4G26_11245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G4G26_11250	COG0159	tryptophan synthase activity
G4G26_11255	COG0133	tryptophan synthase activity
G4G26_11260	COG0135	phosphoribosylanthranilate isomerase activity
G4G26_11270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G4G26_11275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G4G26_11280	COG4401	Chorismate mutase type I
G4G26_11285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G4G26_11290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G4G26_11295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G4G26_11300	COG0105	UTP biosynthetic process
G4G26_11305	COG0142	geranyltranstransferase activity
G4G26_11310	COG2226	methyltransferase
G4G26_11315	COG0142	geranyltranstransferase activity
G4G26_11325	COG0302	gtp cyclohydrolase
G4G26_11330	COG0776	regulation of translation
G4G26_11335	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G4G26_11350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G4G26_11355	COG1160	GTP binding
G4G26_11380	COG1304	FMN binding
G4G26_11385	COG0539	negative regulation of cytoplasmic translation
G4G26_11390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G4G26_11400	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
G4G26_11405	COG2959	enzyme of heme biosynthesis
G4G26_11410	COG3409	Peptidoglycan-binding domain 1 protein
G4G26_11410	COG3773	Cell wall hydrolase
G4G26_11415	COG2339	peptidase activity
G4G26_11420	COG0492	ferredoxin-NADP+ reductase activity
G4G26_11425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G4G26_11430	COG4862	establishment of competence for transformation
G4G26_11435	COG1408	metallophosphoesterase
G4G26_11445	COG1388	LysM domain
G4G26_11450	COG1266	CAAX protease self-immunity
G4G26_11455	COG0514	ATP-dependent DNA helicase (RecQ)
G4G26_11460	COG4955	Helix-turn-helix domain
G4G26_11465	COG1141	Ferredoxin
G4G26_11470	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
G4G26_11475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G4G26_11480	COG0710	3-dehydroquinate dehydratase activity
G4G26_11490	COG1595	DNA-templated transcription, initiation
G4G26_11495	COG5002	protein histidine kinase activity
G4G26_11500	COG0745	RESPONSE REGULATOR receiver
G4G26_11505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G4G26_11510	COG1333	cytochrome c biogenesis protein
G4G26_11515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G26_11520	COG1187	pseudouridine synthase activity
G4G26_11525	COG0700	Nucleoside recognition
G4G26_11530	COG2715	membrane protein required for spore maturation
G4G26_11535	COG1686	Belongs to the peptidase S11 family
G4G26_11545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G4G26_11550	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G4G26_11555	COG1547	Domain of unknown function (DUF309)
G4G26_11560	COG0456	acetyltransferase
G4G26_11565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G4G26_11570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G4G26_11570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G4G26_11575	COG0307	riboflavin synthase, alpha
G4G26_11580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G4G26_11580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G4G26_11590	COG0681	Belongs to the peptidase S26 family
G4G26_11600	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
G4G26_11635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G4G26_11640	COG4086	secreted protein
G4G26_11645	COG0019	diaminopimelate decarboxylase activity
G4G26_11650	COG0697	spore germination
G4G26_11665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4G26_11685	COG1191	sigma factor activity
G4G26_11690	COG2172	sigma factor antagonist activity
G4G26_11695	COG1366	Belongs to the anti-sigma-factor antagonist family
G4G26_11700	COG1686	Belongs to the peptidase S11 family
G4G26_11705	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G4G26_11710	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G4G26_11715	COG4974	Belongs to the 'phage' integrase family
G4G26_11725	COG0735	belongs to the Fur family
G4G26_11730	COG1300	Membrane
G4G26_11740	COG0281	malic enzyme
G4G26_11745	COG1757	Na H antiporter
G4G26_11750	COG1027	Aspartate ammonia-lyase
G4G26_11755	COG0252	asparaginase activity
G4G26_11760	COG1396	sequence-specific DNA binding
G4G26_11765	COG1379	DNA repair
G4G26_11770	COG0494	nUDIX hydrolase
G4G26_11780	COG0667	Aldo Keto reductase
G4G26_11790	COG1073	alpha beta
G4G26_11800	COG4918	Iron-sulphur cluster biosynthesis
G4G26_11805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G4G26_11805	COG0456	acetyltransferase
G4G26_11810	COG2329	Antibiotic biosynthesis monooxygenase
G4G26_11815	COG0456	acetyltransferase
G4G26_11825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G4G26_11835	COG2211	Major facilitator Superfamily
G4G26_11845	COG0346	lactoylglutathione lyase activity
G4G26_11850	COG1072	(Pantothenic acid kinase))
G4G26_11855	COG3048	D-serine ammonia-lyase activity
G4G26_11860	COG0300	oxidoreductase activity
G4G26_11865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G26_11870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G4G26_11875	COG4187	Peptidase family M20/M25/M40
G4G26_11880	COG1902	pentaerythritol trinitrate reductase activity
G4G26_11885	COG0596	Alpha beta hydrolase
G4G26_11895	COG1234	tRNA 3'-trailer cleavage
G4G26_11900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G4G26_11905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G4G26_11910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G4G26_11920	COG0706	membrane insertase activity
G4G26_11925	COG3361	conserved protein (COG2071)
G4G26_11930	COG2195	Cleaves the N-terminal amino acid of tripeptides
G4G26_11935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G4G26_11940	COG0346	lactoylglutathione lyase activity
G4G26_11950	COG1376	ErfK ybiS ycfS ynhG family protein
G4G26_11955	COG4129	membrane
G4G26_11960	COG1126	abc transporter atp-binding protein
G4G26_11965	COG0765	amino acid transport
G4G26_11970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G26_11980	COG1597	lipid kinase activity
G4G26_11985	COG2814	Major facilitator Superfamily
G4G26_11990	COG0789	Transcriptional regulator
G4G26_11990	COG4978	Transcriptional regulator
G4G26_11995	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4G26_12000	COG0022	dehydrogenase e1 component
G4G26_12005	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4G26_12010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4G26_12015	COG3426	butyrate kinase activity
G4G26_12020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G4G26_12025	COG0280	phosphate acetyltransferase
G4G26_12030	COG3829	transcription factor binding
G4G26_12030	COG3290	protein histidine kinase activity
G4G26_12040	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G4G26_12045	COG2079	MmgE PrpD family protein
G4G26_12050	COG0372	Belongs to the citrate synthase family
G4G26_12055	COG1960	acyl-CoA dehydrogenase activity
G4G26_12060	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4G26_12065	COG0183	Belongs to the thiolase family
G4G26_12070	COG0584	glycerophosphoryl diester phosphodiesterase
G4G26_12075	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4G26_12090	COG1902	pentaerythritol trinitrate reductase activity
G4G26_12095	COG0745	RESPONSE REGULATOR receiver
G4G26_12100	COG0750	zinc metalloprotease
G4G26_12105	COG0497	DNA recombination
G4G26_12110	COG1438	arginine binding
G4G26_12115	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
G4G26_12120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G4G26_12125	COG0142	geranyltranstransferase activity
G4G26_12130	COG1722	exodeoxyribonuclease VII activity
G4G26_12135	COG1570	exodeoxyribonuclease VII activity
G4G26_12140	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G4G26_12145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G4G26_12150	COG1302	Protein conserved in bacteria
G4G26_12155	COG0439	Biotin carboxylase
G4G26_12160	COG0511	ligase activity, forming carbon-carbon bonds
G4G26_12200	COG3854	ATPases associated with a variety of cellular activities
G4G26_12210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G4G26_12215	COG0006	proline dipeptidase activity
G4G26_12220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G4G26_12230	COG3872	metal-dependent enzyme
G4G26_12240	COG1752	Esterase of the alpha-beta hydrolase superfamily
G4G26_12245	COG1321	iron dependent repressor
G4G26_12250	COG0095	Lipoate-protein ligase
G4G26_12255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4G26_12260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G4G26_12265	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G4G26_12270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G4G26_12275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G4G26_12290	COG1396	sequence-specific DNA binding
G4G26_12300	COG0681	Belongs to the peptidase S26 family
G4G26_12325	COG4940	Competence protein ComGF
G4G26_12335	COG4970	Tfp pilus assembly protein FimT
G4G26_12340	COG4537	Required for transformation and DNA binding
G4G26_12345	COG1459	type II secretion system
G4G26_12350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G4G26_12355	COG0517	IMP dehydrogenase activity
G4G26_12360	COG0598	Magnesium transport protein CorA
G4G26_12365	COG1253	flavin adenine dinucleotide binding
G4G26_12370	COG1366	Belongs to the anti-sigma-factor antagonist family
G4G26_12380	COG1393	Belongs to the ArsC family
G4G26_12390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G26_12400	COG0011	TIGRFAM Protein of
G4G26_12410	COG2866	Carboxypeptidase
G4G26_12415	COG1368	sulfuric ester hydrolase activity
G4G26_12420	COG1940	carbohydrate kinase activity
G4G26_12425	COG4483	Protein conserved in bacteria
G4G26_12430	COG0705	Rhomboid family
G4G26_12430	COG0457	Tetratricopeptide repeat
G4G26_12440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G4G26_12450	COG0438	transferase activity, transferring glycosyl groups
G4G26_12465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G4G26_12470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4G26_12475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4G26_12480	COG0581	inorganic phosphate transmembrane transporter activity
G4G26_12485	COG0573	inorganic phosphate transmembrane transporter activity
G4G26_12490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G4G26_12500	COG0477	Major facilitator Superfamily
G4G26_12505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G4G26_12510	COG2839	Protein conserved in bacteria
G4G26_12515	COG5521	maltodextrose utilization protein MalA
G4G26_12520	COG1388	LysM domain
G4G26_12525	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G4G26_12530	COG4709	membrane
G4G26_12535	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
G4G26_12540	COG0735	belongs to the Fur family
G4G26_12545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4G26_12555	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G4G26_12560	COG0513	Belongs to the DEAD box helicase family
G4G26_12570	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G4G26_12575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G4G26_12580	COG2384	SAM-dependent methyltransferase
G4G26_12585	COG2010	Cytochrome c
G4G26_12590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G4G26_12595	COG0358	DNA primase activity
G4G26_12600	COG1671	Belongs to the UPF0178 family
G4G26_12605	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G4G26_12610	COG0517	IMP dehydrogenase activity
G4G26_12615	COG0751	glycine-tRNA ligase activity
G4G26_12620	COG0752	glycyl-tRNA synthetase alpha subunit
G4G26_12625	COG1381	Involved in DNA repair and RecF pathway recombination
G4G26_12635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G4G26_12640	COG0295	cytidine deaminase activity
G4G26_12645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G4G26_12650	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G4G26_12655	COG1480	7TM receptor with intracellular HD hydrolase
G4G26_12660	COG1702	phosphate starvation-inducible protein PhoH
G4G26_12665	COG0561	phosphatase activity
G4G26_12680	COG4864	UPF0365 protein
G4G26_12685	COG1030	water channel activity
G4G26_12690	COG1610	YqeY-like protein
G4G26_12700	COG1283	sodium-dependent phosphate transmembrane transporter activity
G4G26_12705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G4G26_12710	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G4G26_12715	COG2264	protein methyltransferase activity
G4G26_12720	COG0484	heat shock protein binding
G4G26_12725	COG0443	Heat shock 70 kDa protein
G4G26_12730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G4G26_12735	COG1420	regulation of RNA biosynthetic process
G4G26_12740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G4G26_12745	COG0481	GTPase activity
G4G26_12755	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4G26_12760	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G4G26_12765	COG0268	Binds directly to 16S ribosomal RNA
G4G26_12770	COG1466	dna polymerase III delta subunit
G4G26_12785	COG0658	competence protein
G4G26_12785	COG2333	competence protein COMEC
G4G26_12790	COG2131	deaminase
G4G26_12795	COG1596	polysaccharide export
G4G26_12795	COG1555	photosystem II stabilization
G4G26_12800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G4G26_12805	COG2226	methyltransferase
G4G26_12810	COG0799	negative regulation of ribosome biogenesis
G4G26_12815	COG1713	HD superfamily hydrolase involved in NAD metabolism
G4G26_12820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G4G26_12825	COG1534	Rna-binding protein
G4G26_12830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G4G26_12835	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G4G26_12840	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
G4G26_12850	COG2755	lipolytic protein G-D-S-L family
G4G26_12855	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4G26_12855	COG3409	Peptidoglycan-binding domain 1 protein
G4G26_12860	COG0398	Pfam SNARE associated Golgi protein
G4G26_12865	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G4G26_12875	COG3209	COG3209 Rhs family protein
G4G26_12885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G4G26_12890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4G26_12895	COG0798	PFAM Bile acid sodium symporter
G4G26_12900	COG0346	lactoylglutathione lyase activity
G4G26_12905	COG0640	Transcriptional regulator
G4G26_12910	COG3403	YqcI/YcgG family
G4G26_12930	COG0604	alcohol dehydrogenase
G4G26_12955	COG0457	Tetratricopeptide repeat
G4G26_12970	COG5444	nuclease activity
G4G26_12995	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4G26_12995	COG3409	Peptidoglycan-binding domain 1 protein
G4G26_13000	COG4824	toxin secretion phage lysis holin
G4G26_13030	COG3778	Protein conserved in bacteria
G4G26_13035	COG3299	homolog of phage Mu protein gp47
G4G26_13040	COG3628	GPW Gp25 family protein
G4G26_13050	COG4193	domain, Protein
G4G26_13060	COG5280	Phage tail tape measure protein TP901
G4G26_13060	COG3953	SLT domain
G4G26_13120	COG4653	Phage capsid family
G4G26_13125	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G4G26_13135	COG2369	cell adhesion
G4G26_13140	COG5518	Phage portal protein
G4G26_13145	COG1783	phage Terminase large subunit
G4G26_13150	COG5484	DNA packaging
G4G26_13160	COG3677	Transposase
G4G26_13175	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
G4G26_13185	COG1484	DNA-dependent DNA replication
G4G26_13190	COG3935	DnaD domain protein
G4G26_13195	COG3723	Recombinational DNA repair protein, rece pathway
G4G26_13200	COG5377	YqaJ viral recombinase family
G4G26_13230	COG1476	TRANSCRIPTIONal
G4G26_13235	COG3620	sequence-specific DNA binding
G4G26_13245	COG0563	adenylate kinase activity
G4G26_13250	COG2856	Zn peptidase
G4G26_13270	COG4124	Belongs to the glycosyl hydrolase 26 family
G4G26_13275	COG0730	response to heat
G4G26_13280	COG0425	Belongs to the sulfur carrier protein TusA family
G4G26_13285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4G26_13285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G26_13295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4G26_13295	COG0425	Belongs to the sulfur carrier protein TusA family
G4G26_13300	COG2210	Belongs to the sulfur carrier protein TusA family
G4G26_13305	COG1937	Protein conserved in bacteria
G4G26_13310	COG0662	Cupin 2, conserved barrel domain protein
G4G26_13320	COG0789	Transcriptional regulator
G4G26_13320	COG4978	Transcriptional regulator
G4G26_13325	COG2814	Major facilitator Superfamily
G4G26_13330	COG0456	acetyltransferase
G4G26_13335	COG1253	flavin adenine dinucleotide binding
G4G26_13345	COG0697	spore germination
G4G26_13350	COG0583	DNA-binding transcription factor activity
G4G26_13355	COG2072	flavoprotein involved in K transport
G4G26_13360	COG1230	cation diffusion facilitator family transporter
G4G26_13370	COG1114	Component of the transport system for branched-chain amino acids
G4G26_13375	COG1687	branched-chain amino acid
G4G26_13380	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G4G26_13385	COG1522	sequence-specific DNA binding
G4G26_13390	COG2124	cytochrome p450
G4G26_13400	COG1335	isochorismatase
G4G26_13415	COG2318	DinB family
G4G26_13425	COG2070	2-Nitropropane dioxygenase
G4G26_13435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G4G26_13445	COG2186	Transcriptional regulator
G4G26_13460	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_13465	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G4G26_13470	COG3959	Transketolase, thiamine diphosphate binding domain
G4G26_13480	COG4978	Transcriptional regulator
G4G26_13480	COG0789	Transcriptional regulator
G4G26_13485	COG2315	Protein conserved in bacteria
G4G26_13495	COG3443	Belongs to the bacterial solute-binding protein 9 family
G4G26_13500	COG1595	DNA-templated transcription, initiation
G4G26_13505	COG0667	Aldo Keto reductase
G4G26_13510	COG2851	Citrate transporter
G4G26_13515	COG0583	DNA-binding transcription factor activity
G4G26_13520	COG2828	Protein conserved in bacteria
G4G26_13525	COG3409	Peptidoglycan-binding domain 1 protein
G4G26_13530	COG5566	PFAM Mor transcription activator
G4G26_13535	COG0596	Alpha beta hydrolase
G4G26_13540	COG4991	sh3 domain protein
G4G26_13545	COG4991	sh3 domain protein
G4G26_13555	COG0346	lactoylglutathione lyase activity
G4G26_13565	COG5577	PFAM Coat F domain
G4G26_13570	COG1063	alcohol dehydrogenase
G4G26_13580	COG5577	PFAM Coat F domain
G4G26_13585	COG0789	Transcriptional regulator
G4G26_13595	COG1064	alcohol dehydrogenase
G4G26_13600	COG0693	protein deglycase activity
G4G26_13605	COG1621	beta-fructofuranosidase activity
G4G26_13610	COG3716	PTS system mannose fructose sorbose family IID component
G4G26_13615	COG3715	PTS system
G4G26_13620	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4G26_13625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4G26_13630	COG3933	PFAM sigma-54 factor interaction domain-containing protein
G4G26_13630	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G4G26_13640	COG1113	amino acid transport
G4G26_13645	COG1280	lysine exporter protein (LysE YggA)
G4G26_13650	COG1378	Sugar-specific transcriptional regulator TrmB
G4G26_13655	COG1595	DNA-templated transcription, initiation
G4G26_13665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G4G26_13665	COG2755	lipolytic protein G-D-S-L family
G4G26_13675	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G4G26_13675	COG2124	cytochrome p450
G4G26_13680	COG1309	transcriptional regulator
G4G26_13685	COG2226	methyltransferase
G4G26_13700	COG2116	formate transmembrane transporter activity
G4G26_13705	COG5609	conserved protein (DUF2294)
G4G26_13710	COG3383	formate dehydrogenase (NAD+) activity
G4G26_13715	COG2427	Protein of unknown function (DUF1641)
G4G26_13725	COG0626	cystathionine gamma-synthase activity
G4G26_13730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4G26_13735	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G4G26_13740	COG2226	methyltransferase
G4G26_13755	COG0768	penicillin binding
G4G26_13760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G4G26_13765	COG0572	uridine kinase
G4G26_13780	COG4122	O-methyltransferase activity
G4G26_13785	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G4G26_13790	COG3906	Belongs to the UPF0473 family
G4G26_13795	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G4G26_13800	COG4472	Bacterial protein of unknown function (DUF965)
G4G26_13805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G4G26_13810	COG0628	permease
G4G26_13815	COG1126	abc transporter atp-binding protein
G4G26_13820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G26_13825	COG0765	amino acid transport
G4G26_13830	COG0765	amino acid transport
G4G26_13845	COG3881	PFAM PRC-barrel domain
G4G26_13850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G4G26_13855	COG0457	Tetratricopeptide repeat
G4G26_13860	COG0482	sulfurtransferase activity
G4G26_13865	COG1104	cysteine desulfurase activity
G4G26_13870	COG1959	2 iron, 2 sulfur cluster binding
G4G26_13875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G4G26_13880	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G4G26_13890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G4G26_13895	COG0124	histidyl-tRNA synthetase
G4G26_13905	COG4991	sh3 domain protein
G4G26_13905	COG3103	Sh3 type 3 domain protein
G4G26_13905	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4G26_13910	COG1490	D-aminoacyl-tRNA deacylase activity
G4G26_13915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G4G26_13920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G4G26_13925	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
G4G26_13925	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G4G26_13930	COG5416	Lipopolysaccharide assembly protein A domain
G4G26_13935	COG0490	domain, Protein
G4G26_13940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G4G26_13940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G4G26_13950	COG2244	polysaccharide biosynthetic process
G4G26_13955	COG2323	membrane
G4G26_13965	COG1862	Preprotein translocase
G4G26_13970	COG0343	queuine tRNA-ribosyltransferase activity
G4G26_13975	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G4G26_13985	COG2255	four-way junction helicase activity
G4G26_13990	COG0632	four-way junction helicase activity
G4G26_14000	COG2814	Major facilitator Superfamily
G4G26_14005	COG0673	inositol 2-dehydrogenase activity
G4G26_14010	COG2112	serine threonine protein kinase
G4G26_14030	COG1115	amino acid carrier protein
G4G26_14035	COG0217	transcriptional regulatory protein
G4G26_14045	COG1388	LysM domain
G4G26_14050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G4G26_14055	COG0157	Belongs to the NadC ModD family
G4G26_14060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G4G26_14065	COG1104	cysteine desulfurase activity
G4G26_14070	COG1827	regulation of RNA biosynthetic process
G4G26_14075	COG0077	Prephenate dehydratase
G4G26_14080	COG4492	Belongs to the UPF0735 family
G4G26_14085	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G4G26_14090	COG3290	protein histidine kinase activity
G4G26_14100	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G4G26_14105	COG2868	ribosomal protein
G4G26_14110	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G4G26_14115	COG1994	Peptidase M50
G4G26_14120	COG0739	heme binding
G4G26_14125	COG2894	cell division
G4G26_14130	COG0850	regulation of cytokinetic process
G4G26_14135	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G4G26_14145	COG1077	Cell shape determining protein MreB Mrl
G4G26_14150	COG2003	Belongs to the UPF0758 family
G4G26_14155	COG0424	maF-like protein
G4G26_14165	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G4G26_14170	COG0285	dihydrofolate synthase activity
G4G26_14175	COG0525	valine-tRNA ligase activity
G4G26_14185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4G26_14190	COG1388	LysM domain
G4G26_14195	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G4G26_14200	COG0113	porphobilinogen synthase activity
G4G26_14205	COG1587	Uroporphyrinogen-III synthase
G4G26_14210	COG0181	hydroxymethylbilane synthase activity
G4G26_14215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G4G26_14220	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G4G26_14230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G4G26_14235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G4G26_14240	COG1067	ATP-dependent peptidase activity
G4G26_14240	COG0470	DNA polymerase III
G4G26_14245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G4G26_14250	COG0544	peptidyl-prolyl cis-trans isomerase activity
G4G26_14255	COG1477	protein flavinylation
G4G26_14255	COG0457	Tetratricopeptide repeat
G4G26_14260	COG0066	3-isopropylmalate dehydratase activity
G4G26_14265	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G4G26_14270	COG0473	3-isopropylmalate dehydrogenase activity
G4G26_14275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G4G26_14280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G4G26_14285	COG0440	acetolactate synthase activity
G4G26_14290	COG0028	Belongs to the TPP enzyme family
G4G26_14300	COG0454	-acetyltransferase
G4G26_14305	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
G4G26_14315	COG0622	Phosphoesterase
G4G26_14320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G4G26_14325	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G4G26_14330	COG5401	PFAM Sporulation and spore germination
G4G26_14335	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G4G26_14340	COG1846	Transcriptional regulator
G4G26_14345	COG2197	response regulator
G4G26_14350	COG0824	Thioesterase
G4G26_14355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G4G26_14360	COG1053	succinate dehydrogenase
G4G26_14365	COG2009	succinate dehydrogenase
G4G26_14370	COG1719	4-vinyl reductase, 4VR
G4G26_14375	COG0527	aspartate kinase activity
G4G26_14380	COG0322	excinuclease ABC activity
G4G26_14385	COG3118	belongs to the thioredoxin family
G4G26_14390	COG3534	alpha-L-arabinofuranosidase
G4G26_14395	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G4G26_14400	COG2086	electron transfer activity
G4G26_14405	COG1024	Enoyl-CoA hydratase
G4G26_14410	COG1309	transcriptional regulator
G4G26_14415	COG0318	PFAM AMP-dependent synthetase and ligase
G4G26_14420	COG3766	membrane
G4G26_14425	COG1193	negative regulation of DNA recombination
G4G26_14430	COG1796	DNA polymerase
G4G26_14430	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G4G26_14435	COG1286	toxin biosynthetic process
G4G26_14440	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
G4G26_14445	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G4G26_14450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4G26_14450	COG0072	phenylalanine-tRNA ligase activity
G4G26_14455	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G4G26_14465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4G26_14475	COG3835	regulator
G4G26_14480	COG0277	FAD linked oxidase domain protein
G4G26_14485	COG0247	lactate metabolic process
G4G26_14500	COG1966	Carbon starvation protein
G4G26_14505	COG3534	alpha-L-arabinofuranosidase
G4G26_14510	COG0395	ABC-type sugar transport system, permease component
G4G26_14515	COG1175	transmembrane transport
G4G26_14520	COG1653	transport
G4G26_14525	COG0371	Dehydrogenase
G4G26_14530	COG0647	UMP catabolic process
G4G26_14535	COG0235	Class ii aldolase
G4G26_14540	COG1069	ribulokinase activity
G4G26_14545	COG2160	L-arabinose isomerase activity
G4G26_14550	COG3507	Belongs to the glycosyl hydrolase 43 family
G4G26_14555	COG1363	Peptidase, m42
G4G26_14565	COG3326	Membrane
G4G26_14570	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G4G26_14575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G4G26_14580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G4G26_14590	COG1346	cytolysis
G4G26_14595	COG1380	Effector of murein hydrolase LrgA
G4G26_14600	COG3279	Response regulator of the LytR AlgR family
G4G26_14605	COG3275	phosphorelay sensor kinase activity
G4G26_14610	COG1011	Hydrolase
G4G26_14615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G4G26_14625	COG0398	Pfam SNARE associated Golgi protein
G4G26_14630	COG1484	DNA-dependent DNA replication
G4G26_14635	COG3611	Membrane attachment protein
G4G26_14640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G4G26_14645	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G4G26_14650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4G26_14655	COG1733	regulation of RNA biosynthetic process
G4G26_14660	COG2814	Major facilitator Superfamily
G4G26_14665	COG0656	L-ascorbic acid biosynthetic process
G4G26_14670	COG0237	dephospho-CoA kinase activity
G4G26_14675	COG1971	Probably functions as a manganese efflux pump
G4G26_14680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G4G26_14685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4G26_14685	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4G26_14690	COG5002	protein histidine kinase activity
G4G26_14695	COG0745	RESPONSE REGULATOR receiver
G4G26_14700	COG0039	L-malate dehydrogenase activity
G4G26_14705	COG0538	isocitrate dehydrogenase activity
G4G26_14710	COG0372	Belongs to the citrate synthase family
G4G26_14715	COG2707	UPF0756 membrane protein
G4G26_14720	COG0628	permease
G4G26_14725	COG3030	protein affecting phage T7 exclusion by the F plasmid
G4G26_14730	COG0469	pyruvate kinase activity
G4G26_14735	COG0205	6-phosphofructokinase activity
G4G26_14740	COG0825	malonyl-CoA metabolic process
G4G26_14745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G4G26_14750	COG0281	malic enzyme
G4G26_14755	COG0587	DNA-directed DNA polymerase activity
G4G26_14775	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G4G26_14785	COG4109	DRTGG domain
G4G26_14790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G4G26_14795	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_14805	COG0165	Argininosuccinate lyase
G4G26_14810	COG0137	argininosuccinate synthase activity
G4G26_14815	COG0521	Mo-molybdopterin cofactor biosynthetic process
G4G26_14820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G4G26_14830	COG0827	DNA restriction-modification system
G4G26_14835	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
G4G26_14840	COG3874	Sporulation protein YtfJ
G4G26_14850	COG1714	RDD family
G4G26_14855	COG0616	signal peptide processing
G4G26_14860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G4G26_14865	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G4G26_14870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G4G26_14880	COG0301	tRNA thio-modification
G4G26_14885	COG1104	cysteine desulfurase activity
G4G26_14890	COG1114	Component of the transport system for branched-chain amino acids
G4G26_14895	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
G4G26_14900	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G4G26_14905	COG1309	transcriptional regulator
G4G26_14910	COG1956	GAF domain-containing protein
G4G26_14915	COG2203	Gaf domain
G4G26_14915	COG2199	diguanylate cyclase activity
G4G26_14925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G4G26_14930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G4G26_14935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G4G26_14940	COG0454	-acetyltransferase
G4G26_14945	COG0517	IMP dehydrogenase activity
G4G26_14950	COG0123	including yeast histone deacetylase and acetoin utilization protein
G4G26_14955	COG1360	Flagellar Motor Protein
G4G26_14960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G4G26_14965	COG1609	Transcriptional regulator
G4G26_14970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G4G26_14970	COG1605	Chorismate mutase
G4G26_14975	COG3118	belongs to the thioredoxin family
G4G26_14980	COG4980	gas vesicle protein
G4G26_14985	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
G4G26_14990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G4G26_14995	COG1674	ftsk spoiiie
G4G26_15000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4G26_15005	COG4848	Belongs to the UPF0354 family
G4G26_15010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G26_15025	COG1363	Peptidase, m42
G4G26_15030	COG5584	Small secreted protein
G4G26_15035	COG0281	malic enzyme
G4G26_15040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G26_15045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G4G26_15055	COG0510	thiamine kinase activity
G4G26_15060	COG1523	belongs to the glycosyl hydrolase 13 family
G4G26_15065	COG1597	lipid kinase activity
G4G26_15075	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G4G26_15080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4G26_15085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4G26_15090	COG2252	PERMEase
G4G26_15095	COG4473	ABC transporter
G4G26_15100	COG1131	(ABC) transporter
G4G26_15105	COG1349	DNA-binding transcription factor activity
G4G26_15110	COG1187	pseudouridine synthase activity
G4G26_15115	COG2244	polysaccharide biosynthetic process
G4G26_15120	COG2081	HI0933 family
G4G26_15125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G4G26_15135	COG5578	integral membrane protein
G4G26_15140	COG0673	inositol 2-dehydrogenase activity
G4G26_15145	COG1653	transport
G4G26_15150	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
G4G26_15155	COG4209	transmembrane transport
G4G26_15160	COG2207	Transcriptional regulator
G4G26_15165	COG1653	transport
G4G26_15170	COG0395	ABC-type sugar transport system, permease component
G4G26_15175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4G26_15180	COG2124	cytochrome p450
G4G26_15185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G4G26_15195	COG0156	8-amino-7-oxononanoate synthase activity
G4G26_15200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4G26_15210	COG1073	alpha beta
G4G26_15215	COG1609	Transcriptional regulator
G4G26_15220	COG1653	transport
G4G26_15225	COG1175	transmembrane transport
G4G26_15230	COG0395	ABC-type sugar transport system, permease component
G4G26_15235	COG1486	melibiose metabolic process
G4G26_15240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4G26_15245	COG0495	leucyl-tRNA aminoacylation
G4G26_15255	COG1366	Belongs to the anti-sigma-factor antagonist family
G4G26_15255	COG2202	Pas domain
G4G26_15260	COG2814	Major facilitator Superfamily
G4G26_15265	COG2433	Pfam Transposase IS66
G4G26_15270	COG0577	efflux transmembrane transporter activity
G4G26_15275	COG1136	(ABC) transporter
G4G26_15280	COG2205	protein histidine kinase activity
G4G26_15285	COG0745	RESPONSE REGULATOR receiver
G4G26_15290	COG0577	efflux transmembrane transporter activity
G4G26_15295	COG1136	(ABC) transporter
G4G26_15310	COG1131	(ABC) transporter
G4G26_15315	COG1725	Transcriptional regulator
G4G26_15330	COG1242	4 iron, 4 sulfur cluster binding
G4G26_15335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
G4G26_15345	COG2267	carboxylic ester hydrolase activity
G4G26_15350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G4G26_15355	COG1113	amino acid transport
G4G26_15360	COG0367	asparagine synthase
G4G26_15365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G4G26_15370	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G4G26_15380	COG1506	peptidase
G4G26_15385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G26_15390	COG1116	anion transmembrane transporter activity
G4G26_15395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G26_15400	COG0494	nUDIX hydrolase
G4G26_15405	COG4824	toxin secretion phage lysis holin
G4G26_15410	COG0783	Belongs to the Dps family
G4G26_15425	COG1854	S-ribosylhomocysteine lyase activity
G4G26_15430	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G4G26_15435	COG0288	reversible hydration of carbon dioxide
G4G26_15440	COG0254	rRNA binding
G4G26_15445	COG1271	oxidase subunit
G4G26_15450	COG1294	oxidase, subunit
G4G26_15460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4G26_15465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4G26_15465	COG1321	iron dependent repressor
G4G26_15470	COG1121	(ABC) transporter
G4G26_15475	COG0803	Belongs to the bacterial solute-binding protein 9 family
G4G26_15480	COG4948	Mandelate Racemase Muconate Lactonizing
G4G26_15485	COG0318	PFAM AMP-dependent synthetase and ligase
G4G26_15490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G4G26_15495	COG0596	Alpha beta hydrolase
G4G26_15500	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G4G26_15505	COG1169	isochorismate synthase
G4G26_15510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4G26_15515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G4G26_15520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G4G26_15525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4G26_15530	COG0438	transferase activity, transferring glycosyl groups
G4G26_15540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4G26_15545	COG0438	transferase activity, transferring glycosyl groups
G4G26_15550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4G26_15555	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
G4G26_15560	COG0058	SHG alpha-glucan phosphorylase activity
G4G26_15565	COG0297	glycogen (starch) synthase activity
G4G26_15570	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G4G26_15575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G4G26_15580	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G4G26_15705	COG3859	Proton-coupled thiamine transporter YuaJ
G4G26_15710	COG1247	-acetyltransferase
G4G26_15715	COG2268	Band 7 protein
G4G26_15720	COG1585	Membrane protein implicated in regulation of membrane protease activity
G4G26_15725	COG2318	DinB family
G4G26_15735	COG1454	alcohol dehydrogenase
G4G26_15740	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_15745	COG1510	regulation of RNA biosynthetic process
G4G26_15755	COG0569	domain protein
G4G26_15760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G4G26_15765	COG4682	membrane
G4G26_15770	COG1705	Flagellar rod assembly protein muramidase FlgJ
G4G26_15775	COG0477	Major facilitator Superfamily
G4G26_15780	COG5553	Cysteine dioxygenase type I
G4G26_15790	COG1968	undecaprenyl-diphosphatase activity
G4G26_15795	COG0628	permease
G4G26_15800	COG0673	inositol 2-dehydrogenase activity
G4G26_15805	COG4806	L-rhamnose isomerase
G4G26_15810	COG3254	rhamnose metabolic process
G4G26_15815	COG1070	Carbohydrate kinase
G4G26_15820	COG1349	DNA-binding transcription factor activity
G4G26_15825	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_15825	COG3347	Dehydrogenase
G4G26_15830	COG0840	transmembrane signaling receptor activity
G4G26_15835	COG0840	transmembrane signaling receptor activity
G4G26_15840	COG0840	transmembrane signaling receptor activity
G4G26_15845	COG0840	transmembrane signaling receptor activity
G4G26_15860	COG0432	Pfam Uncharacterised protein family UPF0047
G4G26_15870	COG0366	Alpha amylase catalytic
G4G26_15875	COG1253	flavin adenine dinucleotide binding
G4G26_15880	COG2738	Putative neutral zinc metallopeptidase
G4G26_15895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G4G26_15910	COG0166	Belongs to the GPI family
G4G26_15915	COG1979	alcohol dehydrogenase
G4G26_15920	COG1979	alcohol dehydrogenase
G4G26_15925	COG2155	Conserved Protein
G4G26_15930	COG1098	S1 RNA binding domain
G4G26_15935	COG0436	Aminotransferase
G4G26_15940	COG1522	sequence-specific DNA binding
G4G26_15945	COG2267	carboxylic ester hydrolase activity
G4G26_15955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G4G26_15960	COG2205	protein histidine kinase activity
G4G26_15970	COG5018	Exonuclease
G4G26_15980	COG2814	Major facilitator Superfamily
G4G26_15985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4G26_15990	COG3011	Protein conserved in bacteria
G4G26_16000	COG3290	protein histidine kinase activity
G4G26_16005	COG4565	transcriptional regulatory protein
G4G26_16030	COG3493	citrate carrier protein
G4G26_16040	COG2111	Na H antiporter
G4G26_16040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G4G26_16045	COG2111	Na H antiporter
G4G26_16050	COG1006	Multisubunit Na H antiporter MnhC subunit
G4G26_16055	COG0651	ATP synthesis coupled electron transport
G4G26_16060	COG1863	multisubunit Na H antiporter MnhE subunit
G4G26_16065	COG2212	antiporter activity
G4G26_16070	COG1320	monovalent cation:proton antiporter activity
G4G26_16075	COG2050	protein possibly involved in aromatic compounds catabolism
G4G26_16080	COG2197	response regulator
G4G26_16085	COG4585	Histidine kinase
G4G26_16095	COG0142	geranyltranstransferase activity
G4G26_16115	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G4G26_16120	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G4G26_16125	COG1335	isochorismatase
G4G26_16130	COG5506	Protein of unknown function (DUF1694)
G4G26_16145	COG0628	permease
G4G26_16160	COG1418	mRNA catabolic process
G4G26_16165	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_16175	COG1511	domain protein
G4G26_16180	COG0433	COG0433 Predicted ATPase
G4G26_16180	COG1674	ftsk spoiiie
G4G26_16185	COG4499	WXG100 protein secretion system (Wss), protein YukC
G4G26_16190	COG5417	Belongs to the EsaB family
G4G26_16195	COG4842	Belongs to the WXG100 family
G4G26_16200	COG2508	Transcriptional regulator
G4G26_16200	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G4G26_16205	COG0686	Belongs to the AlaDH PNT family
G4G26_16210	COG5634	Uncharacterized conserved protein (DUF2278)
G4G26_16215	COG3251	PFAM MbtH domain protein
G4G26_16220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_16225	COG1535	isochorismatase
G4G26_16225	COG3433	isochorismatase activity
G4G26_16230	COG1021	2,3-dihydroxybenzoate-AMP ligase
G4G26_16235	COG1169	isochorismate synthase
G4G26_16240	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_16245	COG2819	hydrolase of the alpha beta superfamily
G4G26_16250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G4G26_16255	COG1268	BioY protein
G4G26_16260	COG2056	Na+-H+ antiporter family
G4G26_16265	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G4G26_16270	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
G4G26_16275	COG3584	3D domain protein
G4G26_16290	COG1252	NADH dehydrogenase
G4G26_16295	COG0492	ferredoxin-NADP+ reductase activity
G4G26_16305	COG0516	GMP reductase activity
G4G26_16310	COG2808	Putative FMN-binding domain
G4G26_16315	COG0456	acetyltransferase
G4G26_16320	COG0316	Belongs to the HesB IscA family
G4G26_16325	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G4G26_16330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4G26_16335	COG4844	belongs to the
G4G26_16340	COG1252	NADH dehydrogenase
G4G26_16345	COG4837	Protein of unknown function (DUF1462)
G4G26_16350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G4G26_16355	COG1506	peptidase
G4G26_16355	COG4946	Tricorn protease homolog
G4G26_16355	COG0823	Involved in the tonB-independent uptake of proteins
G4G26_16360	COG0083	homoserine kinase activity
G4G26_16365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G4G26_16370	COG0460	homoserine dehydrogenase
G4G26_16375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4G26_16380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G4G26_16385	COG0647	UMP catabolic process
G4G26_16390	COG2445	Protein of unknown function DUF86
G4G26_16395	COG4470	Protein conserved in bacteria
G4G26_16405	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G4G26_16410	COG0739	heme binding
G4G26_16420	COG3377	Domain of unknown function (DUF1805)
G4G26_16425	COG0737	Belongs to the 5'-nucleotidase family
G4G26_16430	COG0730	response to heat
G4G26_16435	COG1801	Protein of unknown function DUF72
G4G26_16445	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G4G26_16450	COG2508	Transcriptional regulator
G4G26_16455	COG2233	PERMEase
G4G26_16460	COG2233	PERMEase
G4G26_16465	COG3648	Uricase
G4G26_16465	COG3195	allantoin biosynthetic process
G4G26_16470	COG2351	hydroxyisourate hydrolase activity
G4G26_16480	COG2080	2 iron, 2 sulfur cluster binding
G4G26_16485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G4G26_16490	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G4G26_16495	COG2068	MobA-Related Protein
G4G26_16500	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G4G26_16505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G4G26_16510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4G26_16520	COG2356	endonuclease I
G4G26_16525	COG3842	ATPase activity
G4G26_16530	COG2188	Transcriptional regulator
G4G26_16535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4G26_16540	COG0395	ABC-type sugar transport system, permease component
G4G26_16545	COG1175	transmembrane transport
G4G26_16550	COG1653	transport
G4G26_16555	COG2222	sugar isomerase
G4G26_16560	COG0322	excinuclease ABC activity
G4G26_16565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G26_16580	COG0719	Fe-S assembly protein
G4G26_16585	COG0822	iron-sulfur transferase activity
G4G26_16590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4G26_16595	COG0719	Fe-S assembly protein
G4G26_16600	COG0396	ATPase activity
G4G26_16610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4G26_16615	COG1464	Belongs to the NlpA lipoprotein family
G4G26_16620	COG2011	ABC-type metal ion transport system permease component
G4G26_16625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G4G26_16635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G26_16640	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G4G26_16650	COG0509	glycine decarboxylation via glycine cleavage system
G4G26_16655	COG1393	Belongs to the ArsC family
G4G26_16660	COG1960	acyl-CoA dehydrogenase activity
G4G26_16665	COG0183	Belongs to the thiolase family
G4G26_16670	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4G26_16670	COG1024	Enoyl-CoA hydratase
G4G26_16680	COG0506	proline dehydrogenase activity
G4G26_16690	COG5577	PFAM Coat F domain
G4G26_16695	COG1846	Transcriptional regulator
G4G26_16700	COG0477	Major facilitator Superfamily
G4G26_16705	COG1942	4-Oxalocrotonate Tautomerase
G4G26_16710	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_16715	COG0583	DNA-binding transcription factor activity
G4G26_16725	COG1120	ATPase activity
G4G26_16740	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_16745	COG0783	Belongs to the Dps family
G4G26_16750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4G26_16755	COG0745	RESPONSE REGULATOR receiver
G4G26_16760	COG2205	protein histidine kinase activity
G4G26_16760	COG2770	Histidine kinase
G4G26_16770	COG1309	transcriptional regulator
G4G26_16775	COG0114	fumarate hydratase activity
G4G26_16785	COG0697	spore germination
G4G26_16790	COG0814	amino acid
G4G26_16800	COG2197	response regulator
G4G26_16805	COG4585	Histidine kinase
G4G26_16810	COG4758	membrane
G4G26_16815	COG3595	metallopeptidase activity
G4G26_16820	COG1842	Phage shock protein A
G4G26_16825	COG4758	membrane
G4G26_16830	COG2814	Major facilitator Superfamily
G4G26_16835	COG2096	Adenosyltransferase
G4G26_16840	COG1120	ATPase activity
G4G26_16845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G26_16850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4G26_16855	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_16860	COG3386	PFAM SMP-30 Gluconolaconase
G4G26_16865	COG2205	protein histidine kinase activity
G4G26_16870	COG0745	RESPONSE REGULATOR receiver
G4G26_16880	COG1191	sigma factor activity
G4G26_16890	COG2140	Oxalate decarboxylase
G4G26_16900	COG0577	efflux transmembrane transporter activity
G4G26_16905	COG1136	(ABC) transporter
G4G26_16910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G26_16915	COG1120	ATPase activity
G4G26_16920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G26_16925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G26_16930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4G26_16935	COG0531	amino acid
G4G26_16945	COG1988	membrane-bound metal-dependent
G4G26_16950	COG1368	sulfuric ester hydrolase activity
G4G26_16955	COG1910	domain protein
G4G26_16960	COG0725	ABC transporter, periplasmic molybdate-binding protein
G4G26_16965	COG4149	molybdate abc transporter
G4G26_16970	COG0656	L-ascorbic acid biosynthetic process
G4G26_16980	COG0025	NhaP-type Na H and K H
G4G26_16985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4G26_16990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G4G26_16995	COG3973	AAA domain
G4G26_17000	COG2860	membrane
G4G26_17005	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G4G26_17010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G4G26_17015	COG2217	Heavy metal translocating P-type atpase
G4G26_17020	COG2217	Heavy metal translocating P-type atpase
G4G26_17025	COG2608	mercury ion transmembrane transporter activity
G4G26_17030	COG1937	Protein conserved in bacteria
G4G26_17035	COG0673	inositol 2-dehydrogenase activity
G4G26_17040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G4G26_17045	COG1289	transmembrane transporter activity
G4G26_17055	COG2076	Multidrug Resistance protein
G4G26_17060	COG1309	transcriptional regulator
G4G26_17065	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_17075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G4G26_17080	COG0557	exoribonuclease II activity
G4G26_17085	COG1647	Serine aminopeptidase, S33
G4G26_17090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G4G26_17095	COG0596	Alpha beta hydrolase
G4G26_17100	COG1476	TRANSCRIPTIONal
G4G26_17105	COG1396	sequence-specific DNA binding
G4G26_17110	COG1396	sequence-specific DNA binding
G4G26_17115	COG1733	regulation of RNA biosynthetic process
G4G26_17120	COG0840	transmembrane signaling receptor activity
G4G26_17125	COG1174	glycine betaine transport
G4G26_17130	COG1732	Glycine betaine
G4G26_17135	COG1174	glycine betaine transport
G4G26_17140	COG0517	IMP dehydrogenase activity
G4G26_17140	COG1125	glycine betaine transport
G4G26_17145	COG1510	regulation of RNA biosynthetic process
G4G26_17150	COG1174	glycine betaine transport
G4G26_17155	COG1732	Glycine betaine
G4G26_17160	COG1174	glycine betaine transport
G4G26_17165	COG0517	IMP dehydrogenase activity
G4G26_17165	COG1125	glycine betaine transport
G4G26_17170	COG1510	regulation of RNA biosynthetic process
G4G26_17185	COG3064	Membrane
G4G26_17190	COG4640	response to antibiotic
G4G26_17195	COG0456	acetyltransferase
G4G26_17210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4G26_17230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4G26_17235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4G26_17245	COG2234	aminopeptidase activity
G4G26_17250	COG0148	phosphopyruvate hydratase activity
G4G26_17255	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G4G26_17260	COG0149	triose-phosphate isomerase activity
G4G26_17265	COG0126	phosphoglycerate kinase activity
G4G26_17270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4G26_17275	COG2390	Transcriptional regulator
G4G26_17280	COG2814	Major facilitator Superfamily
G4G26_17285	COG1609	Transcriptional regulator
G4G26_17290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G26_17295	COG0583	DNA-binding transcription factor activity
G4G26_17300	COG0697	spore germination
G4G26_17305	COG1113	amino acid transport
G4G26_17310	COG3858	chitin binding
G4G26_17315	COG1556	Lactate utilization protein
G4G26_17320	COG1139	Iron-sulfur cluster binding protein
G4G26_17325	COG0247	lactate metabolic process
G4G26_17330	COG2197	response regulator
G4G26_17335	COG4585	Histidine kinase
G4G26_17340	COG0842	Transport permease protein
G4G26_17345	COG1131	(ABC) transporter
G4G26_17350	COG0596	Alpha beta hydrolase
G4G26_17355	COG2208	phosphoserine phosphatase activity
G4G26_17360	COG3867	Arabinogalactan endo-beta-1,4-galactanase
G4G26_17365	COG1874	Beta-galactosidase
G4G26_17370	COG3833	ABC-type maltose transport systems, permease component
G4G26_17375	COG1175	transmembrane transport
G4G26_17380	COG2182	Extracellular solute-binding protein
G4G26_17385	COG1609	Transcriptional regulator
G4G26_17390	COG2186	Transcriptional regulator
G4G26_17395	COG1620	l-lactate permease
G4G26_17400	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G4G26_17410	COG5039	Polysaccharide pyruvyl transferase
G4G26_17415	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4G26_17420	COG0110	maltose O-acetyltransferase activity
G4G26_17425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G4G26_17430	COG2244	polysaccharide biosynthetic process
G4G26_17435	COG1216	Glycosyl transferase, family 2
G4G26_17440	COG5039	Polysaccharide pyruvyl transferase
G4G26_17445	COG1216	Glycosyl transferase, family 2
G4G26_17455	COG0438	transferase activity, transferring glycosyl groups
G4G26_17460	COG1215	transferase activity, transferring glycosyl groups
G4G26_17465	COG0438	transferase activity, transferring glycosyl groups
G4G26_17470	COG1086	Polysaccharide biosynthesis protein
G4G26_17475	COG0489	protein tyrosine kinase activity
G4G26_17480	COG3944	biosynthesis protein
G4G26_17485	COG1396	sequence-specific DNA binding
G4G26_17490	COG2272	Belongs to the type-B carboxylesterase lipase family
G4G26_17500	COG3479	Phenolic acid decarboxylase
G4G26_17515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4G26_17520	COG1621	beta-fructofuranosidase activity
G4G26_17525	COG1621	beta-fructofuranosidase activity
G4G26_17530	COG0531	amino acid
G4G26_17535	COG1309	transcriptional regulator
G4G26_17540	COG2076	Multidrug Resistance protein
G4G26_17545	COG2076	Multidrug Resistance protein
G4G26_17555	COG0277	FAD linked oxidase domain protein
G4G26_17560	COG3621	Patatin-like phospholipase
G4G26_17570	COG0740	serine-type endopeptidase activity
G4G26_17575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G4G26_17580	COG0366	Alpha amylase catalytic
G4G26_17585	COG1554	hydrolase, family 65, central catalytic
G4G26_17590	COG5521	maltodextrose utilization protein MalA
G4G26_17595	COG3833	ABC-type maltose transport systems, permease component
G4G26_17600	COG1175	transmembrane transport
G4G26_17605	COG2182	Extracellular solute-binding protein
G4G26_17610	COG0366	Alpha amylase catalytic
G4G26_17615	COG1609	Transcriptional regulator
G4G26_17620	COG1611	Belongs to the LOG family
G4G26_17625	COG1694	Mazg nucleotide pyrophosphohydrolase
G4G26_17630	COG0659	secondary active sulfate transmembrane transporter activity
G4G26_17635	COG0288	reversible hydration of carbon dioxide
G4G26_17640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4G26_17645	COG0577	efflux transmembrane transporter activity
G4G26_17650	COG1136	(ABC) transporter
G4G26_17655	COG5002	protein histidine kinase activity
G4G26_17660	COG0745	RESPONSE REGULATOR receiver
G4G26_17670	COG2162	N-hydroxyarylamine O-acetyltransferase activity
G4G26_17675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4G26_17680	COG1481	regulation of sporulation
G4G26_17685	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G4G26_17690	COG1660	Displays ATPase and GTPase activities
G4G26_17695	COG1051	belongs to the nudix hydrolase family
G4G26_17700	COG0492	ferredoxin-NADP+ reductase activity
G4G26_17705	COG0791	NLP P60 protein
G4G26_17705	COG3883	PFAM NLP P60 protein
G4G26_17710	COG0457	Tetratricopeptide repeat
G4G26_17715	COG1132	(ABC) transporter
G4G26_17735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G4G26_17735	COG0140	phosphoribosyl-ATP diphosphatase activity
G4G26_17740	COG0107	imidazoleglycerol-phosphate synthase activity
G4G26_17745	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G4G26_17750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G4G26_17755	COG0131	Imidazoleglycerol-phosphate dehydratase
G4G26_17760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G4G26_17765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G4G26_17770	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
G4G26_17775	COG4990	cell redox homeostasis
G4G26_17780	COG5297	Belongs to the glycosyl hydrolase family 6
G4G26_17785	COG0110	maltose O-acetyltransferase activity
G4G26_17790	COG0546	phosphoglycolate phosphatase activity
G4G26_17795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G4G26_17800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G4G26_17805	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G4G26_17810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G4G26_17815	COG0363	glucosamine-6-phosphate deaminase activity
G4G26_17820	COG2188	Transcriptional regulator
G4G26_17825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G4G26_17830	COG1950	PFAM Membrane protein of
G4G26_17835	COG1983	PspC domain protein
G4G26_17840	COG3595	metallopeptidase activity
G4G26_17860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G4G26_17865	COG0556	nucleotide-excision repair
G4G26_17870	COG4897	Protein conserved in bacteria
G4G26_17875	COG3848	Pyruvate phosphate dikinase
G4G26_17875	COG0574	Belongs to the PEP-utilizing enzyme family
G4G26_17880	COG1309	transcriptional regulator
G4G26_17885	COG2814	Major facilitator Superfamily
G4G26_17890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4G26_17900	COG0793	Belongs to the peptidase S41A family
G4G26_17900	COG3409	Peptidoglycan-binding domain 1 protein
G4G26_17905	COG2177	Part of the ABC transporter FtsEX involved in
G4G26_17910	COG2884	Cell division ATP-binding protein ftsE
G4G26_17915	COG2010	Cytochrome c
G4G26_17920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4G26_17930	COG0653	protein targeting
G4G26_17935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G4G26_17950	COG1516	flagellar protein fliS
G4G26_17955	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G4G26_17960	COG1334	flagellar protein FlaG
G4G26_17965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G4G26_17970	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G4G26_17975	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
G4G26_17985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G4G26_17990	COG4786	Flagellar basal body rod
G4G26_17990	COG1256	bacterial-type flagellum assembly
G4G26_17995	COG3418	PFAM FlgN family protein
G4G26_18000	COG2747	anti-sigma28 factor FlgM
G4G26_18010	COG1040	competence protein
G4G26_18020	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
G4G26_18025	COG1307	EDD domain protein, DegV family
G4G26_18030	COG2197	response regulator
G4G26_18035	COG4585	Histidine kinase
G4G26_18040	COG1739	Uncharacterized protein family UPF0029
G4G26_18045	COG1316	TRANSCRIPTIONal
G4G26_18050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G4G26_18055	COG0438	transferase activity, transferring glycosyl groups
G4G26_18060	COG1215	transferase activity, transferring glycosyl groups
G4G26_18065	COG3206	protein involved in exopolysaccharide biosynthesis
G4G26_18070	COG3307	-O-antigen
G4G26_18075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G4G26_18080	COG0297	glycogen (starch) synthase activity
G4G26_18080	COG0438	transferase activity, transferring glycosyl groups
G4G26_18085	COG2244	polysaccharide biosynthetic process
G4G26_18095	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4G26_18095	COG2247	cell wall binding repeat
G4G26_18100	COG2247	cell wall binding repeat
G4G26_18100	COG2385	sporulation resulting in formation of a cellular spore
G4G26_18110	COG1316	TRANSCRIPTIONal
G4G26_18115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G4G26_18120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G4G26_18130	COG1215	transferase activity, transferring glycosyl groups
G4G26_18130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G4G26_18135	COG0463	Glycosyl transferase, family 2
G4G26_18150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G4G26_18155	COG1134	teichoic acid transport
G4G26_18160	COG1682	transport, permease protein
G4G26_18165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G4G26_18170	COG0438	transferase activity, transferring glycosyl groups
G4G26_18175	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G4G26_18180	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
G4G26_18185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G4G26_18195	COG4193	domain, Protein
G4G26_18200	COG1482	cell wall glycoprotein biosynthetic process
G4G26_18205	COG0697	spore germination
G4G26_18210	COG0814	amino acid
G4G26_18220	COG2814	Major facilitator Superfamily
G4G26_18225	COG1316	TRANSCRIPTIONal
G4G26_18230	COG0561	phosphatase activity
G4G26_18235	COG0791	NLP P60 protein
G4G26_18245	COG2843	Capsule synthesis protein
G4G26_18255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G4G26_18260	COG1609	Transcriptional regulator
G4G26_18265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4G26_18270	COG1869	D-ribose catabolic process
G4G26_18275	COG1129	ABC transporter
G4G26_18280	COG1172	Belongs to the binding-protein-dependent transport system permease family
G4G26_18285	COG1879	ABC-type sugar transport system periplasmic component
G4G26_18290	COG3103	Sh3 type 3 domain protein
G4G26_18300	COG2249	NAD(P)H dehydrogenase (quinone) activity
G4G26_18305	COG3527	Alpha-acetolactate decarboxylase
G4G26_18310	COG0028	Belongs to the TPP enzyme family
G4G26_18315	COG0583	DNA-binding transcription factor activity
G4G26_18320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G4G26_18335	COG5337	Spore coat protein CotH
G4G26_18345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G4G26_18355	COG0405	Gamma-glutamyltransferase
G4G26_18360	COG1522	sequence-specific DNA binding
G4G26_18365	COG2059	Chromate
G4G26_18370	COG2059	Chromate
G4G26_18380	COG0655	NAD(P)H dehydrogenase (quinone) activity
G4G26_18385	COG0583	DNA-binding transcription factor activity
G4G26_18400	COG5444	nuclease activity
G4G26_18420	COG3878	Protein conserved in bacteria
G4G26_18425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G4G26_18430	COG4464	protein tyrosine phosphatase activity
G4G26_18435	COG0489	protein tyrosine kinase activity
G4G26_18440	COG3944	biosynthesis protein
G4G26_18450	COG4715	Zinc finger, swim domain protein
G4G26_18455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G4G26_18460	COG0561	phosphatase activity
G4G26_18465	COG1349	DNA-binding transcription factor activity
G4G26_18470	COG0629	single-stranded DNA binding
G4G26_18485	COG3764	Sortase (surface protein transpeptidase)
G4G26_18490	COG0745	RESPONSE REGULATOR receiver
G4G26_18490	COG2972	Histidine kinase
G4G26_18495	COG1970	mechanosensitive ion channel activity
G4G26_18500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G4G26_18505	COG0457	Tetratricopeptide repeat
G4G26_18510	COG4786	Flagellar basal body rod
G4G26_18515	COG4786	Flagellar basal body rod
G4G26_18520	COG1077	Cell shape determining protein MreB Mrl
G4G26_18525	COG1609	Transcriptional regulator
G4G26_18535	COG1846	Transcriptional regulator
G4G26_18540	COG2814	Major facilitator Superfamily
G4G26_18545	COG3420	alginic acid biosynthetic process
G4G26_18550	COG1953	Uracil, thiamine, allantoin
G4G26_18555	COG0477	Major facilitator Superfamily
G4G26_18560	COG1335	isochorismatase
G4G26_18570	COG0004	ammonium transporteR
G4G26_18575	COG0347	Belongs to the P(II) protein family
G4G26_18580	COG0671	phosphoesterase, PA-phosphatase related
G4G26_18590	COG0739	heme binding
G4G26_18595	COG1247	-acetyltransferase
G4G26_18615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4G26_18620	COG0789	Transcriptional regulator
G4G26_18635	COG1959	2 iron, 2 sulfur cluster binding
G4G26_18640	COG0804	urea catabolic process
G4G26_18645	COG0832	Belongs to the urease beta subunit family
G4G26_18650	COG0831	urea catabolic process
G4G26_18665	COG3237	CsbD-like
G4G26_18670	COG1994	Peptidase M50
G4G26_18675	COG0457	Tetratricopeptide repeat
G4G26_18680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G4G26_18685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G4G26_18695	COG2304	oxidoreductase activity
G4G26_18705	COG2304	oxidoreductase activity
G4G26_18710	COG2385	sporulation resulting in formation of a cellular spore
G4G26_18715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G4G26_18725	COG4836	Membrane
G4G26_18735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G4G26_18740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G4G26_18745	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G4G26_18750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G4G26_18755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G4G26_18760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G4G26_18770	COG0356	it plays a direct role in the translocation of protons across the membrane
G4G26_18780	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G4G26_18785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G4G26_18790	COG4475	Protein of unknown function (DUF436)
G4G26_18795	COG0698	ribose 5-phosphate isomerase
G4G26_18800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4G26_18805	COG1971	Probably functions as a manganese efflux pump
G4G26_18810	COG0009	L-threonylcarbamoyladenylate synthase
G4G26_18815	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G4G26_18835	COG2890	protein-(glutamine-N5) methyltransferase activity
G4G26_18840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G4G26_18845	COG0346	lactoylglutathione lyase activity
G4G26_18850	COG0789	Transcriptional regulator
G4G26_18855	COG0679	Auxin Efflux Carrier
G4G26_18860	COG0281	malic enzyme
G4G26_18865	COG1435	thymidine kinase activity
G4G26_18875	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G4G26_18885	COG1494	fructose-1,6-bisphosphatase
G4G26_18890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G4G26_18895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G4G26_18900	COG0191	fructose-bisphosphate aldolase activity
G4G26_18905	COG2204	response regulator
G4G26_18910	COG4821	SIS domain
G4G26_18915	COG0504	CTP synthase activity
G4G26_18920	COG3343	RNA polymerase activity
G4G26_18925	COG1960	acyl-CoA dehydrogenase activity
G4G26_18930	COG2181	nitrate reductase activity
G4G26_18930	COG0247	lactate metabolic process
G4G26_18935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4G26_18940	COG4294	response to UV
G4G26_18950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G4G26_18955	COG1132	(ABC) transporter
G4G26_18960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4G26_18970	COG2181	nitrate reductase activity
G4G26_18975	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G4G26_18980	COG1140	nitrate reductase beta subunit
G4G26_18985	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G4G26_18990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4G26_19000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4G26_19005	COG2223	nitrite transmembrane transporter activity
G4G26_19010	COG0018	arginyl-trna synthetase
G4G26_19015	COG4506	Protein conserved in bacteria
G4G26_19030	COG0535	radical SAM domain protein
G4G26_19040	COG1131	(ABC) transporter
G4G26_19045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G4G26_19050	COG0612	Peptidase, M16
G4G26_19055	COG0612	Peptidase, M16
G4G26_19065	COG3391	amine dehydrogenase activity
G4G26_19070	COG3391	amine dehydrogenase activity
G4G26_19080	COG0457	Tetratricopeptide repeat
G4G26_19110	COG1131	(ABC) transporter
G4G26_19120	COG0010	Belongs to the arginase family
G4G26_19125	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G4G26_19130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4G26_19140	COG1994	Peptidase M50
G4G26_19145	COG1942	4-Oxalocrotonate Tautomerase
G4G26_19150	COG1846	Transcriptional regulator
G4G26_19155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G4G26_19160	COG0477	Major facilitator Superfamily
G4G26_19165	COG1959	2 iron, 2 sulfur cluster binding
G4G26_19170	COG3465	dGTPase activity
G4G26_19175	COG1078	dGTPase activity
G4G26_19180	COG4844	belongs to the
G4G26_19190	COG0697	spore germination
G4G26_19195	COG0095	Lipoate-protein ligase
G4G26_19200	COG0583	DNA-binding transcription factor activity
G4G26_19205	COG0280	phosphate acetyltransferase
G4G26_19215	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_19220	COG0436	Aminotransferase
G4G26_19225	COG2814	Major facilitator Superfamily
G4G26_19230	COG0151	Belongs to the GarS family
G4G26_19235	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_19240	COG1917	Cupin 2, conserved barrel domain protein
G4G26_19245	COG0077	Prephenate dehydratase
G4G26_19250	COG2814	Major facilitator Superfamily
G4G26_19255	COG0833	amino acid
G4G26_19260	COG4187	Peptidase family M20/M25/M40
G4G26_19265	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_19270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G4G26_19280	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G4G26_19285	COG1091	dTDP-4-dehydrorhamnose reductase activity
G4G26_19290	COG1088	dTDP-glucose 4,6-dehydratase activity
G4G26_19295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G4G26_19300	COG3980	spore coat polysaccharide biosynthesis protein
G4G26_19305	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
G4G26_19310	COG2089	acid synthase
G4G26_19315	COG0456	acetyltransferase
G4G26_19320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4G26_19325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G4G26_19330	COG0463	Glycosyl transferase, family 2
G4G26_19340	COG2363	Small membrane protein
G4G26_19345	COG2233	PERMEase
G4G26_19355	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_19360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G4G26_19365	COG1216	Glycosyl transferase, family 2
G4G26_19370	COG0351	phosphomethylpyrimidine kinase
G4G26_19380	COG1621	beta-fructofuranosidase activity
G4G26_19385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4G26_19385	COG1263	PTS System
G4G26_19390	COG2116	formate transmembrane transporter activity
G4G26_19395	COG3711	transcriptional antiterminator
G4G26_19405	COG1404	Belongs to the peptidase S8 family
G4G26_19410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G26_19415	COG0778	Nitroreductase
G4G26_19420	COG0772	Belongs to the SEDS family
G4G26_19430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G4G26_19435	COG1845	cytochrome c oxidase, subunit III
G4G26_19440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G4G26_19445	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G4G26_19450	COG2261	transglycosylase associated protein
G4G26_19455	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
G4G26_19460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G4G26_19465	COG2246	polysaccharide biosynthetic process
G4G26_19470	COG1309	transcriptional regulator
G4G26_19480	COG3162	membrane
G4G26_19485	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4G26_19490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G4G26_19495	COG2837	iron assimilation
G4G26_19500	COG2822	iron ion transport
G4G26_19505	COG0672	)-iron permease
G4G26_19510	COG0352	thiamine-phosphate diphosphorylase activity
G4G26_19515	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
G4G26_19520	COG0583	DNA-binding transcription factor activity
G4G26_19525	COG1380	Effector of murein hydrolase LrgA
G4G26_19530	COG1346	cytolysis
G4G26_19535	COG2814	Major facilitator Superfamily
G4G26_19540	COG4895	conserved protein (DUF2196)
G4G26_19545	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G4G26_19550	COG0346	lactoylglutathione lyase activity
G4G26_19565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4G26_19570	COG1404	Belongs to the peptidase S8 family
G4G26_19575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4G26_19575	COG1263	PTS System
G4G26_19580	COG3711	transcriptional antiterminator
G4G26_19585	COG1442	glycosyl transferase family 8
G4G26_19590	COG5522	Integral membrane protein (intg_mem_TP0381)
G4G26_19595	COG1846	Transcriptional regulator
G4G26_19600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G4G26_19605	COG2234	aminopeptidase activity
G4G26_19620	COG2814	Major facilitator Superfamily
G4G26_19625	COG2357	RelA SpoT domain protein
G4G26_19630	COG1575	Belongs to the MenA family. Type 1 subfamily
G4G26_19645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4G26_19650	COG1696	Membrane protein involved in D-alanine export
G4G26_19655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4G26_19660	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
G4G26_19665	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G4G26_19670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4G26_19675	COG1486	melibiose metabolic process
G4G26_19680	COG1447	Phosphotransferase system cellobiose-specific component IIA
G4G26_19685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4G26_19690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4G26_19695	COG3711	transcriptional antiterminator
G4G26_19695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4G26_19705	COG2094	Belongs to the DNA glycosylase MPG family
G4G26_19710	COG0753	catalase activity
G4G26_19715	COG2814	Major facilitator Superfamily
G4G26_19720	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G4G26_19725	COG1131	(ABC) transporter
G4G26_19745	COG1595	DNA-templated transcription, initiation
G4G26_19750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4G26_19755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G4G26_19760	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G4G26_19765	COG4988	ABC transporter
G4G26_19770	COG1294	oxidase, subunit
G4G26_19775	COG1271	oxidase subunit
G4G26_19780	COG3493	citrate carrier protein
G4G26_19785	COG0501	Belongs to the peptidase M48B family
G4G26_19795	COG0726	polysaccharide deacetylase
G4G26_19800	COG3842	ATPase activity
G4G26_19805	COG2508	Transcriptional regulator
G4G26_19810	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_19815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4G26_19825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G4G26_19835	COG4585	Histidine kinase
G4G26_19840	COG2197	response regulator
G4G26_19845	COG2195	Cleaves the N-terminal amino acid of tripeptides
G4G26_19855	COG4894	glucomannan catabolic process
G4G26_19860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G4G26_19865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G4G26_19870	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_19875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G4G26_19880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G4G26_19885	COG2610	gluconate transmembrane transporter activity
G4G26_19890	COG0500	methyltransferase
G4G26_19895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4G26_19910	COG0753	catalase activity
G4G26_19910	COG0693	protein deglycase activity
G4G26_19915	COG2851	Citrate transporter
G4G26_19920	COG2273	Hydrolase Family 16
G4G26_19925	COG3711	transcriptional antiterminator
G4G26_19935	COG2270	Major facilitator Superfamily
G4G26_19940	COG0513	Belongs to the DEAD box helicase family
G4G26_19945	COG2755	lipolytic protein G-D-S-L family
G4G26_19945	COG3401	FG-GAP repeat protein
G4G26_20000	COG0697	spore germination
G4G26_20005	COG0589	response to stress
G4G26_20010	COG2723	6-phospho-beta-galactosidase activity
G4G26_20015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4G26_20015	COG2190	(PTS) system
G4G26_20015	COG1263	PTS System
G4G26_20030	COG5444	nuclease activity
G4G26_20045	COG3507	Belongs to the glycosyl hydrolase 43 family
G4G26_20060	COG2986	histidine ammonia-lyase
G4G26_20065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G4G26_20070	COG1228	amidohydrolase
G4G26_20075	COG0010	Belongs to the arginase family
G4G26_20080	COG0833	amino acid
G4G26_20085	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G4G26_20090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4G26_20095	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G4G26_20100	COG2390	Transcriptional regulator
G4G26_20110	COG3192	ethanolamine utilization protein
G4G26_20115	COG2079	MmgE PrpD family protein
G4G26_20120	COG1473	amidohydrolase
G4G26_20125	COG1126	abc transporter atp-binding protein
G4G26_20130	COG0765	amino acid transport
G4G26_20135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G26_20140	COG0456	acetyltransferase
G4G26_20145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G26_20150	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
G4G26_20155	COG0561	phosphatase activity
G4G26_20185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4G26_20190	COG5294	Protein conserved in bacteria
G4G26_20195	COG0577	efflux transmembrane transporter activity
G4G26_20200	COG1136	(ABC) transporter
G4G26_20205	COG2205	protein histidine kinase activity
G4G26_20210	COG0745	RESPONSE REGULATOR receiver
G4G26_20215	COG0191	fructose-bisphosphate aldolase activity
G4G26_20220	COG1082	Xylose isomerase domain protein TIM barrel
G4G26_20225	COG1082	Xylose isomerase domain protein TIM barrel
G4G26_20230	COG0673	inositol 2-dehydrogenase activity
G4G26_20235	COG2814	Major facilitator Superfamily
G4G26_20240	COG1082	Xylose isomerase domain protein TIM barrel
G4G26_20245	COG3962	Belongs to the TPP enzyme family
G4G26_20250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4G26_20260	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_20265	COG1349	DNA-binding transcription factor activity
G4G26_20270	COG0667	Aldo Keto reductase
G4G26_20285	COG2814	Major facilitator Superfamily
G4G26_20290	COG0326	Molecular chaperone. Has ATPase activity
G4G26_20300	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_20305	COG1309	transcriptional regulator
G4G26_20310	COG1012	belongs to the aldehyde dehydrogenase family
G4G26_20315	COG1714	RDD family
G4G26_20320	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G4G26_20330	COG1714	RDD family
G4G26_20335	COG2311	Membrane
G4G26_20340	COG1917	Cupin 2, conserved barrel domain protein
G4G26_20345	COG1309	transcriptional regulator
G4G26_20350	COG1028	Short-chain dehydrogenase reductase Sdr
G4G26_20355	COG1846	Transcriptional regulator
G4G26_20360	COG1380	Effector of murein hydrolase LrgA
G4G26_20365	COG1346	cytolysis
G4G26_20370	COG5039	Polysaccharide pyruvyl transferase
G4G26_20375	COG1929	Belongs to the glycerate kinase type-1 family
G4G26_20380	COG1802	Transcriptional regulator
G4G26_20385	COG1070	Carbohydrate kinase
G4G26_20390	COG2610	gluconate transmembrane transporter activity
G4G26_20395	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G4G26_20400	COG0450	alkyl hydroperoxide reductase
G4G26_20405	COG3634	alkyl hydroperoxide reductase activity
G4G26_20420	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
G4G26_20435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G4G26_20450	COG1063	alcohol dehydrogenase
G4G26_20470	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
G4G26_20475	COG0456	acetyltransferase
G4G26_20480	COG0457	Tetratricopeptide repeat
G4G26_20490	COG0010	Belongs to the arginase family
G4G26_20495	COG0833	amino acid
G4G26_20500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G4G26_20520	COG5658	integral membrane protein
G4G26_20525	COG0640	Transcriptional regulator
G4G26_20530	COG3829	transcription factor binding
G4G26_20545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4G26_20550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G4G26_20555	COG4853	Protein conserved in bacteria
G4G26_20560	COG4863	YycH protein
G4G26_20565	COG5002	protein histidine kinase activity
G4G26_20570	COG0745	RESPONSE REGULATOR receiver
G4G26_20600	COG0346	lactoylglutathione lyase activity
G4G26_20605	COG0305	Participates in initiation and elongation during chromosome replication
G4G26_20620	COG3093	addiction module antidote protein HigA
G4G26_20625	COG2807	transmembrane transport
G4G26_20630	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G4G26_20635	COG0359	binds to the 23S rRNA
G4G26_20640	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
G4G26_20645	COG4241	membrane
G4G26_20655	COG5577	PFAM Coat F domain
G4G26_20660	COG1733	regulation of RNA biosynthetic process
G4G26_20665	COG1227	inorganic diphosphatase activity
G4G26_20675	COG2271	Major facilitator Superfamily
G4G26_20680	COG4978	Transcriptional regulator
G4G26_20680	COG0789	Transcriptional regulator
G4G26_20690	COG4319	ketosteroid isomerase
G4G26_20695	COG1357	PFAM Pentapeptide repeats (8 copies)
G4G26_20700	COG2814	Major facilitator Superfamily
G4G26_20705	COG0583	DNA-binding transcription factor activity
G4G26_20710	COG2153	protein acetylation
G4G26_20725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G26_20730	COG1846	Transcriptional regulator
G4G26_20735	COG2153	protein acetylation
G4G26_20740	COG2364	Membrane
G4G26_20745	COG0456	acetyltransferase
G4G26_20750	COG2315	Protein conserved in bacteria
G4G26_20755	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G4G26_20765	COG2814	Major facilitator Superfamily
G4G26_20775	COG1331	Highly conserved protein containing a thioredoxin domain
G4G26_20780	COG0789	Transcriptional regulator
G4G26_20785	COG0697	spore germination
G4G26_20790	COG1331	Highly conserved protein containing a thioredoxin domain
G4G26_20795	COG1266	CAAX protease self-immunity
G4G26_20800	COG0477	Major facilitator Superfamily
G4G26_20800	COG2814	Major facilitator Superfamily
G4G26_20805	COG0110	maltose O-acetyltransferase activity
G4G26_20810	COG0346	lactoylglutathione lyase activity
G4G26_20815	COG1609	Transcriptional regulator
G4G26_20820	COG0708	Exodeoxyribonuclease III
G4G26_20825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G4G26_20830	COG0629	single-stranded DNA binding
G4G26_20835	COG0360	Binds together with S18 to 16S ribosomal RNA
G4G26_20840	COG0012	GTP binding
G4G26_20845	COG0243	molybdopterin cofactor binding
G4G26_20850	COG4481	Protein conserved in bacteria
G4G26_20855	COG3949	Membrane
G4G26_20865	COG1475	DNA binding
G4G26_20870	COG1192	Involved in chromosome partitioning
G4G26_20880	COG1475	DNA binding
G4G26_20885	COG0357	Ribosomal RNA small subunit methyltransferase G
G4G26_20890	COG0445	tRNA wobble uridine modification
G4G26_20895	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G4G26_20900	COG1847	R3H domain protein
G4G26_20905	COG0706	membrane insertase activity
G4G26_20910	COG0594	ribonuclease P activity