locus-tag class description ABU16_0005 ENOG4105C02 permease ABU16_0009 ENOG410904N short-chain dehydrogenase reductase ABU16_0017 ENOG4108K8K Transcriptional regulator ABU16_0018 ENOG4105DCF alanine dehydrogenase ABU16_0020 ENOG4105WQT MbtH domain protein ABU16_0021 ENOG4105CEY Amp-dependent synthetase and ligase ABU16_0022 ENOG4105WQI isochorismatase ABU16_0023 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase ABU16_0024 ENOG4105E4F Isochorismate synthase ABU16_0025 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase ABU16_0026 ENOG4105NIV Esterase ABU16_0030 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) ABU16_0032 ENOG41069ER domain protein ABU16_0035 ENOG4105CEP NADH dehydrogenase ABU16_0036 ENOG4105CAY ferredoxin--nadp reductase ABU16_0040 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 ABU16_0041 ENOG4108YX9 iron--sulfur cluster insertion protein erpA ABU16_0044 ENOG4105ZKE UPF0349 protein ABU16_0047 ENOG41083MR nifu domain-containing protein ABU16_0048 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein ABU16_0049 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) ABU16_0050 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) ABU16_0051 ENOG4105D6E homoserine dehydrogenase ABU16_0054 ENOG4108W5N phosphatidylglycerophosphatase a ABU16_0055 ENOG4105D4U had-superfamily hydrolase, subfamily iia ABU16_0057 ENOG4105MMD transcriptional regulator ABU16_0058 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ABU16_0059 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) ABU16_0060 ENOG4105FAA peptidase M23 ABU16_0061 ENOG4108YTE sporulation protein YunB ABU16_0062 ENOG4105KZD Domain of unknown function (DUF1805) ABU16_0063 ENOG4107R8B 5'-nucleotidase ABU16_0065 ENOG4105I3N Conserved Protein ABU16_0067 ENOG4105CD3 dihydroorotase ABU16_0068 ENOG4105G9B Transcriptional regulator ABU16_0071 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) ABU16_0072 ENOG4105VT2 5-hydroxyisourate hydrolase ABU16_0074 ENOG4107YV9 domain protein ABU16_0075 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding ABU16_0078 ENOG4105XRQ Xanthine dehydrogenase accessory factor ABU16_0079 ENOG4105C5R Aminotransferase ABU16_0082 ENOG4108K8S endonuclease I ABU16_0083 ENOG4108IJ9 (ABC) transporter ABU16_0084 ENOG4105FDP GntR family transcriptional regulator ABU16_0085 ENOG4108KPW sugar kinase ABU16_0086 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component ABU16_0087 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component ABU16_0088 ENOG4105XN3 extracellular solute-binding protein family 1 ABU16_0089 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine ABU16_0090 ENOG4105PKS Excinuclease abc c subunit domain protein ABU16_0091 ENOG4107VFR oxidoreductase ABU16_0092 ENOG4107VFR oxidoreductase ABU16_0095 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase ABU16_0097 ENOG4105DIW FeS assembly protein SUFB ABU16_0098 ENOG4108UNV SUF system FeS assembly protein, NifU family ABU16_0099 ENOG4105C9B Cysteine desulfurase ABU16_0100 ENOG4105JRK feS assembly protein SufD ABU16_0101 ENOG4105C3K feS assembly ATPase SufC ABU16_0106 ENOG4105D01 (LipO)protein ABU16_0107 ENOG4108UMI ABC transporter, permease ABU16_0108 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) ABU16_0114 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) ABU16_0115 ENOG41080E8 Transcriptional regulator, Spx MgsR family ABU16_0116 ENOG4105C1G acyl-Coa dehydrogenase ABU16_0117 ENOG4105CHU acetyl-coa acetyltransferase ABU16_0123 ENOG41067TZ transcriptional regulator, MarR family ABU16_0124 ENOG4105C0R drug resistance transporter emrb qaca subfamily ABU16_0125 ENOG4105MDS 4-oxalocrotonate tautomerase ABU16_0128 ENOG4105EGI Transcriptional regulator ABU16_0130 ENOG4105E0A ABC, transporter ABU16_0133 ENOG4105E1F short-chain dehydrogenase reductase ABU16_0134 ENOG4105HUF DNA protection during starvation protein ABU16_0135 ENOG4105C0H protease ABU16_0137 ENOG4105F3H Histidine kinase ABU16_0139 ENOG41067SE Tetr family transcriptional regulator ABU16_0140 ENOG4105C9Q fumarate hydratase class II ABU16_0145 ENOG4105WH1 Two component transcriptional regulator luxr family ABU16_0146 ENOG4105ENE Histidine kinase ABU16_0149 ENOG41087YS Phage shock protein A ABU16_0153 ENOG4108WBT adenosyltransferase ABU16_0154 ENOG4105E0A ABC, transporter ABU16_0155 ENOG4105EHG Permease protein ABU16_0156 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) ABU16_0158 ENOG4105EWI Short-chain dehydrogenase reductase Sdr ABU16_0159 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein ABU16_0161 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ABU16_0164 ENOG4106DF4 Sigma-70, region 4 ABU16_0167 ENOG4105F0F Oxalate decarboxylase ABU16_0169 ENOG4107RBB ABC transporter, permease ABU16_0170 ENOG4105C19 ABC transporter ABU16_0171 ENOG4108WMK Efflux transporter RND family MFP subunit ABU16_0172 ENOG4105E0A ABC, transporter ABU16_0173 ENOG4105EHG Permease protein ABU16_0174 ENOG4105DQ5 transport system permease protein ABU16_0177 ENOG4105D5Q Arginine ornithine antiporter ABU16_0179 ENOG4107K5X Membrane-bound metal-dependent hydrolase ABU16_0180 ENOG4107QZ2 Sulfatase ABU16_0181 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family ABU16_0182 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein ABU16_0183 ENOG4105E0C molybdate abc transporter ABU16_0186 ENOG4105EEQ Na H antiporter ABU16_0187 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) ABU16_0188 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) ABU16_0189 ENOG4105EEM helicase ABU16_0190 ENOG4105EN6 Membrane ABU16_0193 ENOG4107ZQN disulfide bond ABU16_0194 ENOG4105C59 p-type ATPase ABU16_0195 ENOG4105C59 p-type ATPase ABU16_0196 ENOG410681U heavy metal transport detoxification protein ABU16_0197 ENOG4105VPX protein, conserved in bacteria ABU16_0198 ENOG4105D9R oxidoreductase ABU16_0199 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) ABU16_0200 ENOG4105ME7 Membrane ABU16_0201 ENOG4105RXJ ABU16_0202 ENOG4105KPY Small multidrug resistance protein ABU16_0203 ENOG4105KBX Transcriptional regulator, TetR family ABU16_0204 ENOG4105EWI Short-chain dehydrogenase reductase Sdr ABU16_0205 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) ABU16_0206 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) ABU16_0208 ENOG4105XZU Preprotein translocase, subunit SecG ABU16_0213 ENOG4105KVH Transcriptional regulator ABU16_0214 ENOG4105C8Q Methyl-accepting chemotaxis ABU16_0215 ENOG4105R40 Glycine betaine carnitine choline ABU16_0216 ENOG4108HQR Glycine betaine ABU16_0217 ENOG4105E90 ABC transporter ABU16_0218 ENOG4108IJ8 ABC transporter ABU16_0219 ENOG4107HG4 Transcriptional regulator ABU16_0220 ENOG4105H5S ABU16_0223 ENOG41082BM Transcriptional regulator, arsr family ABU16_0224 ENOG4105R40 Glycine betaine carnitine choline ABU16_0225 ENOG4108HQR Glycine betaine ABU16_0226 ENOG4105E90 ABC transporter ABU16_0227 ENOG4108IJ8 ABC transporter ABU16_0228 ENOG4107HG4 Transcriptional regulator ABU16_0229 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein ABU16_0230 ENOG4108QCI YvbH-like oligomerisation region ABU16_0232 ENOG4105T65 Membrane-associated protein ABU16_0233 ENOG4108W0I acetyltransferase ABU16_0234 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) ABU16_0235 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) ABU16_0236 ENOG4105CP7 Triose-phosphate isomerase ABU16_0237 ENOG4105BZA Phosphoglycerate kinase ABU16_0238 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ABU16_0241 ENOG4105CMD Transcriptional regulator, GntR family ABU16_0242 ENOG4105DEN Luciferase family ABU16_0243 ENOG4105GZI Transcriptional regulator ABU16_0244 ENOG4107RT3 EamA-like transporter family ABU16_0246 ENOG4105VRS hydrolase family 18 ABU16_0247 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) ABU16_0248 ENOG4107QR9 Iron-sulfur cluster binding protein ABU16_0249 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) ABU16_0251 ENOG4105BZU Histidine kinase ABU16_0252 ENOG4105KCT ABC transporter ABU16_0253 ENOG4108M15 ABC transporter ABU16_0255 ENOG4107R6F Alpha Beta Hydrolase Fold protein ABU16_0256 ENOG4108MJI response regulator ABU16_0259 ENOG4105EG2 ABC transporter, permease ABU16_0261 ENOG4107FKK extracellular solute-binding protein family 1 ABU16_0263 ENOG4105JXH GntR family transcriptional regulator ABU16_0264 ENOG4105DAA L-lactate ABU16_0265 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ABU16_0268 ENOG4108ZPC Polysaccharide pyruvyl transferase ABU16_0269 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase ABU16_0270 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family ABU16_0271 ENOG4105D3Q Sugar transferase ABU16_0273 ENOG4105K64 Glycosyl transferase, family 2 ABU16_0275 ENOG4107QRS glycosyltransferase group 2 family protein ABU16_0276 ENOG41068W6 Capsular polysaccharide biosynthesis protein ABU16_0277 ENOG4108KMV Glycosyl transferase (Group 1 ABU16_0278 ENOG4105K64 Glycosyl transferase, family 2 ABU16_0279 ENOG4108PQP glycosyl transferase group 1 ABU16_0281 ENOG4108QV3 biosynthesis protein ABU16_0282 ENOG4105HTX biosynthesis protein ABU16_0284 ENOG4105EBR Carboxylesterase ABU16_0286 ENOG4105PY6 Phenolic acid decarboxylase ABU16_0287 ENOG4105NI3 Protein of unknown function (DUF3237) ABU16_0290 ENOG4105FQP Beta-lactamase ABU16_0291 ENOG4105EDQ levansucrase EC 2.4.1.10 ABU16_0292 ENOG4108HKT sucrose-6-phosphate hydrolase ABU16_0293 ENOG4107QTZ amino acid ABU16_0298 ENOG4105DNP FAD linked oxidase domain protein ABU16_0299 ENOG4105IRW patatin-like phospholipase family protein ABU16_0300 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) ABU16_0301 ENOG4107URF beta-phospho-glucomutase ABU16_0302 ENOG4105CG3 alpha amylase, catalytic region ABU16_0305 ENOG4105EG2 ABC transporter, permease ABU16_0306 ENOG4105D56 permease protein ABU16_0307 ENOG4107FKK extracellular solute-binding protein family 1 ABU16_0308 ENOG4108IUK alpha amylase, catalytic ABU16_0309 ENOG4105FKQ transcriptional regulator ABU16_0310 ENOG4108URH decarboxylase ABU16_0311 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain ABU16_0312 ENOG4105CHH sulfate transporter ABU16_0313 ENOG4108V2W Carbonate dehydratase ABU16_0314 ENOG4105C5I Dehydrogenase ABU16_0316 ENOG4105C19 ABC transporter ABU16_0317 ENOG4105EWM Histidine kinase ABU16_0319 ENOG4107A6P ABU16_0320 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase ABU16_0321 ENOG4105KRI phosphocarrier protein (HPr ABU16_0322 ENOG4105CIE May be required for sporulation (By similarity) ABU16_0323 ENOG4105CHW UPF0052 protein ABU16_0324 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) ABU16_0325 ENOG4108Z4K mutator MutT protein ABU16_0326 ENOG4105C3M thioredoxin reductase ABU16_0329 ENOG4105BZ1 (ABC) transporter ABU16_0331 ENOG4106FGC ABU16_0333 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase ABU16_0334 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) ABU16_0335 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase ABU16_0336 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) ABU16_0337 ENOG4105ECC imidazole-glycerol-phosphate dehydratase ABU16_0338 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) ABU16_0339 ENOG4107RN8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) ABU16_0340 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) ABU16_0342 ENOG4108E16 pectate lyase ABU16_0343 ENOG4108S4C acetyltransferase ABU16_0344 ENOG4107XGZ Hydrolase ABU16_0345 ENOG4105HKU nucleoside recognition domain-containing protein ABU16_0346 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) ABU16_0347 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) ABU16_0348 ENOG4105CE4 GlcNAc 6-P deacetylase ABU16_0349 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) ABU16_0350 ENOG4105FDP GntR family transcriptional regulator ABU16_0351 ENOG41088CQ domain protein ABU16_0353 ENOG4106A3M Cytochrome p-450 ABU16_0354 ENOG410625E ABU16_0358 ENOG41086DT Membrane protein of unknown function ABU16_0359 ENOG41067S9 phage shock protein C, PspC ABU16_0360 ENOG4108PY7 ABU16_0364 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) ABU16_0365 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) ABU16_0369 ENOG4105MKU Transcriptional regulator ABU16_0373 ENOG4105CN1 protease ABU16_0374 ENOG4105CRP Part of the ABC transporter FtsEX involved in ABU16_0375 ENOG4105CAK Cell division ATP-binding protein ftsE ABU16_0378 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) ABU16_0380 ENOG4105MS2 ribosomal subunit Interface protein ABU16_0383 ENOG4105MQ3 flagellar protein FliS ABU16_0384 ENOG4107RT6 flagellar hook-associated ABU16_0385 ENOG41083S7 flagellar protein FlaG ABU16_0386 ENOG4105I03 Flagellin ABU16_0387 ENOG41085Y9 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) ABU16_0388 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) ABU16_0389 ENOG4105MKD ABU16_0390 ENOG4105DTJ flagellar hook-associated protein ABU16_0391 ENOG4105E1Q flagellar hook-associated protein ABU16_0394 ENOG4105RU3 ABU16_0395 ENOG41081UC Inherit from COG: Competence protein ABU16_0399 ENOG4105WH1 Two component transcriptional regulator luxr family ABU16_0400 ENOG4105BZU Histidine kinase ABU16_0401 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein ABU16_0402 ENOG4108KGH TRANSCRIPTIONal ABU16_0403 ENOG4105ESV Glycosyl transferase, family 4 ABU16_0404 ENOG4107EF8 Glycosyl transferase (Group 1 ABU16_0407 ENOG4105QZI O-Antigen Polymerase ABU16_0408 ENOG4105C6Y Udp-glucose 6-dehydrogenase ABU16_0409 ENOG4107RA4 Glycosyl transferase (Group 1 ABU16_0410 ENOG4105PSV Polysaccharide Biosynthesis Protein ABU16_0411 ENOG4105D3Q Sugar transferase ABU16_0412 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase ABU16_0413 ENOG4105JFG SpoIID LytB domain protein ABU16_0416 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase ABU16_0417 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ABU16_0418 ENOG4107VDP teichoic acid biosynthesis ABU16_0419 ENOG41088M2 Glycosyl transferase family 2 ABU16_0421 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ABU16_0422 ENOG4105EY8 ABC transporter ABU16_0424 ENOG4107SJB teichoic acid biosynthesis ABU16_0425 ENOG4108NMT An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity) ABU16_0426 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase ABU16_0428 ENOG4107RZX Teichoic acid biosynthesis protein ABU16_0429 ENOG410651K Teichoic acid biosynthesis protein C ABU16_0431 ENOG4105DG6 mannose-6-phosphate isomerase ABU16_0435 ENOG4108NHD germination protein ABU16_0436 ENOG4105C54 Major Facilitator superfamily ABU16_0437 ENOG4108KGH TRANSCRIPTIONal ABU16_0438 ENOG4105J7I hydrolase ABU16_0439 ENOG4105K4H Nlp p60 protein ABU16_0441 ENOG4105PNM synthesis protein ABU16_0443 ENOG4105N98 Capsule biosynthesis protein capB ABU16_0445 ENOG4105ETE Transcriptional regulator (LacI family ABU16_0446 ENOG4108RVA ribokinase ABU16_0447 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) ABU16_0448 ENOG4105C2J ABC transporter ABU16_0449 ENOG4105CNN ABC, transporter ABU16_0450 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator ABU16_0453 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein ABU16_0454 ENOG4107FQX Alpha-acetolactate decarboxylase ABU16_0456 ENOG4107RSM transcriptional regulator ABU16_0459 ENOG4106UIA ABU16_0461 ENOG4107XC4 flavin reductase domain protein, FMN-binding ABU16_0463 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) ABU16_0465 ENOG4105CAH Chromate ABU16_0466 ENOG4105FGV Chromate ABU16_0468 ENOG4108WS4 fmn reductase ABU16_0469 ENOG4107V2S Transcriptional regulator ABU16_0470 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) ABU16_0475 ENOG4108XI2 Domain of unknown function (DUF1963) ABU16_0476 ENOG4105C6Y Udp-glucose 6-dehydrogenase ABU16_0477 ENOG4108RB3 Capsular polysaccharide biosynthesis protein ABU16_0478 ENOG4107YJ4 chain length determinant protein ABU16_0479 ENOG4105HTX biosynthesis protein ABU16_0481 ENOG4105KBK Zinc finger, swim domain protein ABU16_0482 ENOG4105C0D helicase ABU16_0483 ENOG410667J hydrolase ABU16_0484 ENOG4105E98 transcriptional regulator DeoR family ABU16_0485 ENOG4105Z8H single-stranded DNA-binding protein ABU16_0492 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) ABU16_0493 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) ABU16_0495 ENOG4105CGA flagellar basal-body rod protein FlgG ABU16_0497 ENOG4105DFF Rod shape-determining protein mreb ABU16_0498 ENOG4105MT0 Sporulation transcriptional regulator spoiiid ABU16_0499 ENOG4107MII Sugar-specific transcriptional regulator TrmB ABU16_0500 ENOG4105CZM Major Facilitator ABU16_0501 ENOG4108M26 parallel beta-helix repeat protein ABU16_0502 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease ABU16_0503 ENOG41080V3 Major Facilitator superfamily ABU16_0504 ENOG4105D3W isochorismatase ABU16_0505 ENOG4107P26 ABU16_0506 ENOG4105BZU Histidine kinase ABU16_0508 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase ABU16_0510 ENOG4105FRN stage II sporulation protein ABU16_0511 ENOG4107TCE N-acetyltransferase ABU16_0516 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) ABU16_0517 ENOG4107TXC Transcriptional regulator ABU16_0518 ENOG4106BRK ABU16_0519 ENOG4108RYK Nad-dependent epimerase dehydratase ABU16_0520 ENOG4108Z40 Transcriptional regulator ABU16_0521 ENOG4105CQM Urea amidohydrolase subunit alpha ABU16_0522 ENOG4105KI2 Urea amidohydrolase subunit beta ABU16_0523 ENOG4108YZ9 Urea amidohydrolase subunit gamma ABU16_0530 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) ABU16_0532 ENOG4108TF4 von Willebrand factor, type A ABU16_0536 ENOG4105JFG SpoIID LytB domain protein ABU16_0537 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) ABU16_0539 ENOG4106778 Protein of unknown function (DUF1146) ABU16_0541 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) ABU16_0542 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) ABU16_0543 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) ABU16_0544 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) ABU16_0548 ENOG4107RB6 it plays a direct role in the translocation of protons across the membrane (By similarity) ABU16_0550 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) ABU16_0551 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) ABU16_0552 ENOG4108UIC UPF0340 protein ABU16_0553 ENOG4108YZG isomerase ABU16_0555 ENOG4107WAU Protein tyrosine phosphatase ABU16_0556 ENOG410815N Probably functions as a manganese efflux pump (By similarity) ABU16_0557 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) ABU16_0559 ENOG4108ZXQ stage ii sporulation protein r ABU16_0562 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) ABU16_0563 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) ABU16_0564 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase ABU16_0566 ENOG4107TT2 Auxin Efflux Carrier ABU16_0567 ENOG4105C6K Malic enzyme ABU16_0568 ENOG4107104 thymidine kinase ABU16_0569 ENOG41082DI 50s ribosomal protein l31 ABU16_0570 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) ABU16_0572 ENOG4105CBT Fructose-1,6-bisphosphatase ABU16_0573 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) ABU16_0574 ENOG4107XMI Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway ABU16_0575 ENOG4105D2N Aldolase ABU16_0576 ENOG410812K response regulator receiver protein ABU16_0578 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) ABU16_0581 ENOG4105C1G acyl-Coa dehydrogenase ABU16_0582 ENOG4105DF6 Fe-S oxidoreductase ABU16_0584 ENOG4105E5J UV damage endonuclease ABU16_0586 ENOG4105NAE bifunctional deaminase-reductase domain protein ABU16_0587 ENOG4105BZ1 (ABC) transporter ABU16_0588 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) ABU16_0591 ENOG4105R3A Nitrate reductase ABU16_0592 ENOG4108IUE nitrate reductase beta subunit ABU16_0597 ENOG4107V6Q Cyclic nucleotide-binding domain ABU16_0599 ENOG4105C75 arginyL-tRNA synthetase ABU16_0600 ENOG410684U Domain of unknown function (DUF1934) ABU16_0602 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E ABU16_0612 ENOG4107JM4 Tetratricopeptide repeat ABU16_0613 ENOG4108UIN ybak prolyl-trna synthetase associated region ABU16_0614 ENOG4105CYW agmatinase ABU16_0615 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) ABU16_0616 ENOG4105BZ4 penicillin-binding protein ABU16_0617 ENOG4108XFG YwhD family ABU16_0618 ENOG4108Z4T Peptidase M50 ABU16_0619 ENOG41069HH 4-oxalocrotonate tautomerase ABU16_0620 ENOG41067TZ transcriptional regulator, MarR family ABU16_0621 ENOG4105C22 threonyL-tRNA synthetase ABU16_0623 ENOG4105C57 major facilitator superfamily ABU16_0624 ENOG41062ES Transcriptional regulator ABU16_0626 ENOG4105DCI Phosphohydrolase ABU16_0628 ENOG4108VCI transcription factor, rsfa family ABU16_0629 ENOG4108RNG Permease of the drug metabolite transporter ABU16_0630 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) ABU16_0631 ENOG4105DUM transcriptional regulator, lysR family ABU16_0632 ENOG4108IJ2 phosphate acetyltransferase ABU16_0635 ENOG4105CHM Aminotransferase ABU16_0637 ENOG4108V3M Inherit from COG: acetyl-CoA carboxylase biotin carboxylase ABU16_0638 ENOG4105CHR reductase ABU16_0639 ENOG4106CHD Bacilysin biosynthesis protein bacB ABU16_0640 ENOG41061WN bacilysin biosynthesis protein ABU16_0642 ENOG4105FCW Major Facilitator superfamily ABU16_0645 ENOG4105C26 Dehydrogenase ABU16_0646 ENOG4105D82 Glutamate dehydrogenase ABU16_0648 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase ABU16_0649 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase ABU16_0650 ENOG4105C1B dTDP-glucose 4-6-dehydratase ABU16_0651 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) ABU16_0652 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG ABU16_0653 ENOG4107TY6 Acylneuraminate cytidylyltransferase ABU16_0655 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD ABU16_0656 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase ABU16_0665 ENOG4105C26 Dehydrogenase ABU16_0666 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) ABU16_0667 ENOG4108RJ9 Glycosyl transferase, family 2 ABU16_0671 ENOG4105DWF phosphomethylpyrimidine kinase ABU16_0674 ENOG4105C5Y PTS System ABU16_0675 ENOG4108QTI )-transporter ABU16_0678 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin ABU16_0679 ENOG4105DEN Luciferase family ABU16_0680 ENOG4108DBC nitroreductase ABU16_0683 ENOG41060D1 Quinol oxidase ABU16_0684 ENOG4105CCU oxidase (Subunit III) ABU16_0685 ENOG4105BZ9 Cytochrome C oxidase, subunit I ABU16_0686 ENOG4105E2S oxidase) subunit II ABU16_0687 ENOG4107BMA Transglycosylase associated protein ABU16_0689 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) ABU16_0690 ENOG4105WH5 Teichoic acid glycosylation protein ABU16_0695 ENOG4107ZXU DSBA oxidoreductase ABU16_0696 ENOG4105DBE peroxidase ABU16_0697 ENOG410650H (LipO)protein ABU16_0698 ENOG4107SJW iron permease, FTR1 ABU16_0699 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) ABU16_0701 ENOG4105CMU LysR family (Transcriptional regulator ABU16_0702 ENOG4105VAW lrga family ABU16_0703 ENOG41067MG lrgb family ABU16_0704 ENOG4105D8G Major Facilitator superfamily ABU16_0706 ENOG4105DR4 Methyltransferase ABU16_0710 ENOG4108YV3 Protein of unknown function (DUF2711) ABU16_0711 ENOG4105CK1 PTS System ABU16_0712 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin ABU16_0715 ENOG4105X1N Glycosyl transferase family 8 ABU16_0717 ENOG4105GVJ transcriptional regulator ABU16_0718 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) ABU16_0719 ENOG4105IIU Aminopeptidase ABU16_0721 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase ABU16_0724 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) ABU16_0725 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein ABU16_0727 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD ABU16_0728 ENOG4108VHC Short-chain dehydrogenase reductase Sdr ABU16_0729 ENOG4105CM2 brancheD-chain amino acid aminotransferase ABU16_0730 ENOG4105F8D glycoside hydrolase family 4 ABU16_0731 ENOG4105VCP PTS System ABU16_0732 ENOG4105CK1 PTS System ABU16_0733 ENOG4105VZJ PTS System ABU16_0734 ENOG4105EMD TRANSCRIPTIONal ABU16_0736 ENOG4108VX5 3-methyladenine DNA glycosylase ABU16_0737 ENOG4105CH6 catalase ABU16_0740 ENOG4105DA5 (ABC) transporter ABU16_0741 ENOG41069JR ABU16_0745 ENOG4105ETS cytosine purines uracil thiamine allantoin ABU16_0746 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) ABU16_0748 ENOG4108JJ8 (ABC) transporter ABU16_0749 ENOG4108JJ9 ABC, transporter ABU16_0750 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ABU16_0751 ENOG4105C4M (Ubiquinol oxidase) subunit I ABU16_0752 ENOG4105D2K citrate carrier protein ABU16_0755 ENOG4107BJW polysaccharide deacetylase ABU16_0759 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) ABU16_0761 ENOG4105CMR udp-glucose 4-epimerase ABU16_0764 ENOG4105BZU Histidine kinase ABU16_0765 ENOG4105WH1 Two component transcriptional regulator luxr family ABU16_0766 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) ABU16_0772 ENOG4105DTD Dehydrogenase ABU16_0773 ENOG4108IIH CoA-transferase subunit B ABU16_0774 ENOG4105D6N CoA-transferase, subunit a ABU16_0775 ENOG4105CY2 Citrate transporter ABU16_0777 ENOG4105DHI Methyltransferase ABU16_0782 ENOG4105CH6 catalase ABU16_0783 ENOG4105D4T Citrate transporter ABU16_0784 ENOG4108RZ2 Glycoside hydrolase family 16 ABU16_0786 ENOG4105CID antiterminator ABU16_0789 ENOG4105DEU major facilitator superfamily ABU16_0790 ENOG4105C1J atp-dependent rna helicase ABU16_0791 ENOG4107TDE lipolytic protein G-D-S-L family ABU16_0803 ENOG4105CNA YD repeat protein ABU16_0805 ENOG4107YZX Universal stress protein ABU16_0806 ENOG4105CS2 ec 3.2.1.21 ABU16_0807 ENOG4105C5Y PTS System ABU16_0810 ENOG4107EV6 Inherit from COG: YD repeat protein ABU16_0813 ENOG4106Z5D Glycoside Hydrolase Family 43 ABU16_0816 ENOG4105C84 Histidine ammonia-lyase ABU16_0817 ENOG4105CGP Urocanate hydratase ABU16_0818 ENOG4105CI2 imidazolone-5-propionate hydrolase ABU16_0819 ENOG4107W25 arginase agmatinase formiminoglutamase ABU16_0821 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) ABU16_0822 ENOG4105D9N nucleoside ABU16_0825 ENOG4107RHR regulatoR ABU16_0826 ENOG4108TM9 integral membrane protein ABU16_0827 ENOG4105ENY Ethanolamine utilization protein eutH ABU16_0828 ENOG4108PGP mmge prpd family protein ABU16_0829 ENOG4105CH2 amidohydrolase ABU16_0831 ENOG4108HW4 amino acid AbC transporter ABU16_0832 ENOG4105EAB amino acid AbC transporter ABU16_0833 ENOG4108XSB acetyltransferase, (GNAT) family ABU16_0834 ENOG4105CPU Monooxygenase ABU16_0836 ENOG4107QHE Choloylglycine hydrolase ABU16_0837 ENOG410667J hydrolase ABU16_0843 ENOG4108V5C ABC transporter ABU16_0849 ENOG4105D2N Aldolase ABU16_0850 ENOG4107TRN Xylose isomerase domain protein TIM barrel ABU16_0851 ENOG4105F0H myo-inositol catabolism protein ABU16_0852 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) ABU16_0854 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) ABU16_0855 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) ABU16_0856 ENOG4105D7K pfkb domain protein ABU16_0857 ENOG4105DH8 myo-inositol catabolism ABU16_0858 ENOG4105C26 Dehydrogenase ABU16_0860 ENOG4105CPC Aldo Keto reductase ABU16_0864 ENOG4107QNK )-transporter ABU16_0865 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) ABU16_0867 ENOG41061TZ Short-chain dehydrogenase reductase Sdr ABU16_0868 ENOG4105ST3 Transcriptional regulator ABU16_0869 ENOG4105C26 Dehydrogenase ABU16_0870 ENOG4108YM7 Gcn5-related n-acetyltransferase ABU16_0871 ENOG4105N1N Cupin superfamily protein ABU16_0872 ENOG4107Y1Y Methyltransferase ABU16_0875 ENOG4105CAQ asparagine synthetase ABU16_0876 ENOG4105F22 Major Facilitator Superfamily ABU16_0877 ENOG4108ITS PQQ enzyme repeat ABU16_0879 ENOG41085PJ rdd domain containing protein ABU16_0882 ENOG4105J7D transcriptional regulator ABU16_0883 ENOG4107JEE Short-chain dehydrogenase reductase Sdr ABU16_0884 ENOG41061AU MarR family Transcriptional regulator ABU16_0886 ENOG41067MG lrgb family ABU16_0888 ENOG4105BZW Glycerate kinase ABU16_0889 ENOG4105G3Z GntR family transcriptional regulator ABU16_0890 ENOG4105CMG Carbohydrate kinase ABU16_0891 ENOG4105C6Z Gluconate ABU16_0892 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) ABU16_0893 ENOG4105D3R alkyl hydroperoxide reductase ABU16_0894 ENOG4108JU3 Alkyl hydroperoxide reductase ABU16_0895 ENOG4105CS2 ec 3.2.1.21 ABU16_0897 ENOG4108S3Y transcriptional regulator ABU16_0899 ENOG4106KKU ABU16_0900 ENOG4108Z15 abc transporter atp-binding protein ABU16_0902 ENOG4105Y2Z radical SAM domain protein ABU16_0904 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 ABU16_0907 ENOG41069I7 ABU16_0908 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) ABU16_0910 ENOG4105E2A Dehydrogenase ABU16_0914 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) ABU16_0915 ENOG4105WQG acetyltransferase ABU16_0916 ENOG410780I phosphoprotein phosphatase activity ABU16_0918 ENOG41066UZ arginase EC 3.5.3.1 ABU16_0919 ENOG4108IQI permease ABU16_0920 ENOG4105C8Y Acetylornithine aminotransferase ABU16_0921 ENOG4108JUB Transcriptional regulator ABU16_0922 ENOG4105BZU Histidine kinase ABU16_0927 ENOG4105C0H protease ABU16_0928 ENOG4105Q2H domain protein ABU16_0931 ENOG4105BZU Histidine kinase ABU16_0932 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ABU16_0933 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis ABU16_0934 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase ABU16_0936 ENOG4105CDU Replicative dna helicase ABU16_0940 ENOG4105DJ2 Major Facilitator Superfamily ABU16_0941 ENOG4105EDW glycosyl transferase, family 39 ABU16_0942 ENOG4105K9Q Binds to the 23S rRNA (By similarity) ABU16_0943 ENOG4105BZR domain protein ABU16_0944 ENOG4108XMW Membrane ABU16_0948 ENOG4105KVH Transcriptional regulator ABU16_0949 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase ABU16_0953 ENOG41090E6 transcriptional regulator MERR family ABU16_0955 ENOG4108VSZ Inherit from COG: ketosteroid isomerase-like protein ABU16_0956 ENOG4105DDN Pentapeptide repeat-containing protein ABU16_0957 ENOG4105D94 Major Facilitator Superfamily ABU16_0958 ENOG4107RSM transcriptional regulator ABU16_0959 ENOG41082BV acetyltransferase ABU16_0960 ENOG41081I9 integral membrane protein ABU16_0963 ENOG4108U05 Transcriptional regulator ABU16_0964 ENOG41082BV acetyltransferase ABU16_0966 ENOG4108U7W acetyltransferase ABU16_0967 ENOG4105UNS Pfam:DUF419 ABU16_0968 ENOG4105NAE bifunctional deaminase-reductase domain protein ABU16_0969 ENOG4108J8C transporter major facilitator family protein ABU16_0970 ENOG4105C7Z Conserved Protein ABU16_0971 ENOG4107FCW Abortive infection protein ABU16_0973 ENOG4108UW5 maltose o-acetyltransferase ABU16_0974 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase ABU16_0976 ENOG4105CGK Exodeoxyribonuclease III ABU16_0977 ENOG4108UUM single-stranded DNA-binding protein ABU16_0978 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) ABU16_0979 ENOG4105C3G gtp-binding protein ABU16_0980 ENOG4108J2R molybdopterin oxidoreductase ABU16_0981 ENOG4105VDK protein, conserved in bacteria ABU16_0983 ENOG4108ZDA Sporulation protein YyaC ABU16_0984 ENOG4105FA0 parb-like partition protein ABU16_0985 ENOG4107QJE Chromosome Partitioning Protein ABU16_0988 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) ABU16_0989 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) ABU16_0990 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) ABU16_0993 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) ABU16_0994 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) ABU16_0995 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) ABU16_0996 ENOG410848D S4 domain protein YaaA ABU16_0999 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABU16_1001 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABU16_1003 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) ABU16_1005 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) ABU16_1006 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) ABU16_1007 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) ABU16_1008 ENOG4105ZMH deoxynucleoside kinase ABU16_1010 ENOG4105VRS hydrolase family 18 ABU16_1011 ENOG4105GTG Isochorismatase ABU16_1012 ENOG4108Z6B deaminase ABU16_1013 ENOG4105C6E dna polymerase iii ABU16_1014 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) ABU16_1015 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) ABU16_1017 ENOG41067KS pro-sigma K processing ABU16_1020 ENOG4105CDW Resistance protein ABU16_1021 ENOG4105CXN decarboxylase ABU16_1022 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) ABU16_1023 ENOG4105X0R protein from nitrogen regulatory protein P-II ABU16_1024 ENOG4105XVJ Protein of unknown function (DUF327) ABU16_1025 ENOG4105FA2 dna polymerase iii ABU16_1026 ENOG4105MA4 psp1 domain protein ABU16_1027 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) ABU16_1028 ENOG41060K3 Methyltransferase ABU16_1029 ENOG4105VC4 domain protein ABU16_1030 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) ABU16_1031 ENOG4105KRN Transcriptional regulator, abrb family ABU16_1032 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) ABU16_1033 ENOG4105F8V Hydrolase, tatD family ABU16_1034 ENOG41069ER domain protein ABU16_1036 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) ABU16_1037 ENOG4105XFA sporulation peptidase YabG ABU16_1038 ENOG4105W42 Veg protein ABU16_1039 ENOG4105XEW small acid-soluble spore protein ABU16_1040 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) ABU16_1041 ENOG4105DFT pur operon repressor ABU16_1042 ENOG4105KME endoribonuclease L-psp ABU16_1043 ENOG4105K4W Could be involved in septation (By similarity) ABU16_1045 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) ABU16_1046 ENOG4105C5T Phosphoribosyl pyrophosphate synthase ABU16_1047 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) ABU16_1048 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) ABU16_1050 ENOG4108JA2 transcriptioN-repair coupling factor ABU16_1051 ENOG4108M14 stage v sporulation protein t ABU16_1053 ENOG4108IY2 MazG family ABU16_1054 ENOG41082I2 s4 domain protein ABU16_1055 ENOG4105VYY sporulation protein yabp ABU16_1058 ENOG41060GV RNA binding s1 domain protein ABU16_1062 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) ABU16_1063 ENOG4108UGV hypoxanthine phosphoribosyltransferase ABU16_1064 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) ABU16_1066 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) ABU16_1067 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase ABU16_1068 ENOG4105C6T cysteine synthase ABU16_1069 ENOG4105CRQ synthase (Component I) ABU16_1070 ENOG4105DDQ anthranilate synthase ABU16_1071 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 ABU16_1072 ENOG4105EEI dihydropteroate synthase ABU16_1073 ENOG4105KRF dihydroneopterin aldolase ABU16_1074 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ABU16_1076 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) ABU16_1077 ENOG4105CRK lysyL-tRNA synthetase ABU16_1079 ENOG4108Z0C Uvrb UvrC protein ABU16_1080 ENOG41066A3 ATP guanido phosphotransferase ABU16_1082 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) ABU16_1083 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) ABU16_1084 ENOG4105CTP PilT protein domain protein ABU16_1085 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) ABU16_1086 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) ABU16_1087 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) ABU16_1090 ENOG4105D7W serine acetyltransferase ABU16_1091 ENOG4105C8N cysteinyl-tRNA synthetase ABU16_1092 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) ABU16_1093 ENOG4105C2N RNA methyltransferase TrmH family group 3 ABU16_1094 ENOG4105M0M Tetracycline resistance protein ABU16_1098 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) ABU16_1099 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) ABU16_1101 ENOG4108VZM 50s ribosomal protein L10 ABU16_1102 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) ABU16_1103 ENOG4107Y49 methyltransferase ABU16_1104 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) ABU16_1105 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) ABU16_1106 ENOG4105XPM ribosomal protein ABU16_1107 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) ABU16_1108 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) ABU16_1109 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) ABU16_1110 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) ABU16_1111 ENOG4107SKW Inherit from COG: Alpha beta hydrolase ABU16_1112 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) ABU16_1113 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) ABU16_1114 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) ABU16_1115 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) ABU16_1116 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity ABU16_1117 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) ABU16_1118 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) ABU16_1119 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) ABU16_1120 ENOG41082SA 50s ribosomal protein l29 ABU16_1121 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal ABU16_1123 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits ABU16_1125 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) ABU16_1126 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) ABU16_1127 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) ABU16_1128 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) ABU16_1129 ENOG4105VPB 50S ribosomal protein L30 ABU16_1130 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) ABU16_1131 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) ABU16_1133 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) ABU16_1136 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits ABU16_1137 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) ABU16_1138 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) ABU16_1139 ENOG4108ZT0 50S ribosomal protein l17 ABU16_1140 ENOG4108JJB ABC transporter ABU16_1141 ENOG4108JJB ABC transporter ABU16_1142 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) ABU16_1143 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) ABU16_1144 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) ABU16_1145 ENOG4108UJD 30S ribosomal protein S9 ABU16_1146 ENOG4108I0C methyltransferase ABU16_1149 ENOG4105D1F ATP-binding protein ABU16_1152 ENOG4108NMV polysaccharide deacetylase ABU16_1154 ENOG4105CHH sulfate transporter ABU16_1156 ENOG4108SA1 esterase ABU16_1160 ENOG410874W AraC family transcriptional regulator ABU16_1161 ENOG4105EHZ conserved protein UCP016719 ABU16_1162 ENOG4105D17 glycoside hydrolase, family 3 domain protein ABU16_1166 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate ABU16_1168 ENOG4105EWC Purine nucleoside phosphorylase ABU16_1169 ENOG4105EMN RNA polymerase sigma factor ABU16_1171 ENOG4105C8B TIGR00159 family ABU16_1172 ENOG4107U5W ybbr family ABU16_1173 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) ABU16_1175 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) ABU16_1176 ENOG4105D03 DNA-3-methyladenine glycosylase II ABU16_1178 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ABU16_1179 ENOG4108TWJ NADH dehydrogenase subunit 5 ABU16_1183 ENOG4105GPN Uncharacterized conserved protein (DUF2294) ABU16_1185 ENOG4105WAB arsR family transcriptional regulator ABU16_1186 ENOG4108RWP Major Facilitator Superfamily protein ABU16_1188 ENOG4107ZBH radical SAM domain protein ABU16_1189 ENOG41066N6 Abortive infection protein ABU16_1190 ENOG4108WUZ (ABC) transporter ABU16_1198 ENOG4105G0J serine threonine protein kinase ABU16_1200 ENOG4106K80 ABU16_1202 ENOG4106DDH Sporulation-specific SASP protein ABU16_1204 ENOG4108HWY Beta-lactamase ABU16_1205 ENOG4107E6A Cytochrome p-450 ABU16_1207 ENOG4107QTZ amino acid ABU16_1208 ENOG4107VXM glycerophosphoryl diester phosphodiesterase ABU16_1209 ENOG4105CXY transporter ABU16_1211 ENOG410645S MarR family Transcriptional regulator ABU16_1212 ENOG4105DCM major facilitator superfamily ABU16_1217 ENOG410631K Membrane ABU16_1218 ENOG4106AXJ AraC family transcriptional regulator ABU16_1219 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR ABU16_1220 ENOG4108TCS Glutamyl endopeptidase ABU16_1222 ENOG4108WC5 Alpha Beta Hydrolase Fold protein ABU16_1223 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase ABU16_1224 ENOG4107ZTW SNARE associated Golgi ABU16_1229 ENOG4105C72 UPF0176 protein ABU16_1231 ENOG4108IIZ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane ABU16_1232 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) ABU16_1233 ENOG4108X79 transcriptional regulator ABU16_1235 ENOG4105CM2 brancheD-chain amino acid aminotransferase ABU16_1236 ENOG4108IQI permease ABU16_1237 ENOG4108J5H Homocysteine s-methyltransferase ABU16_1240 ENOG4105CSV Glutaminase ABU16_1243 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase ABU16_1244 ENOG4105C26 Dehydrogenase ABU16_1245 ENOG4105DJB Major Facilitator Superfamily ABU16_1246 ENOG4105EQX glucarate dehydratase ABU16_1247 ENOG41073TP transcriptional regulator ABU16_1248 ENOG4105CTX dehydratase ABU16_1252 ENOG4106UX7 integral membrane protein ABU16_1253 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ABU16_1260 ENOG4105MUA Resistance protein ABU16_1262 ENOG4105DGI Alkaline phosphatase ABU16_1263 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) ABU16_1264 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) ABU16_1265 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) ABU16_1266 ENOG4107EPV Aminotransferase class V ABU16_1267 ENOG4105C0R drug resistance transporter emrb qaca subfamily ABU16_1268 ENOG4105J7D transcriptional regulator ABU16_1269 ENOG4107RB3 L-asparaginase ABU16_1270 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold ABU16_1272 ENOG41060AI SEC-C motif ABU16_1274 ENOG4107Y7X LytTR ABU16_1275 ENOG4108IUW ABC transporter ABU16_1276 ENOG4108SDH ABC, transporter ABU16_1277 ENOG4107SET aldo keto reductase ABU16_1283 ENOG4105H9W Short-chain dehydrogenase reductase Sdr ABU16_1285 ENOG4105DSE periplasmic solute binding protein ABU16_1286 ENOG4105DIK (ABC) transporter ABU16_1288 ENOG4105DEN Luciferase family ABU16_1289 ENOG4108N0M stress protein ABU16_1290 ENOG4106FN3 tellurium resistance protein ABU16_1291 ENOG4106FN3 tellurium resistance protein ABU16_1292 ENOG4107TS3 membrane protein, TerC ABU16_1293 ENOG4108TTB tellurium resistance protein ABU16_1295 ENOG41079KZ Major Facilitator Superfamily ABU16_1296 ENOG4107XZQ multidrug resistance protein ABU16_1297 ENOG4108A65 Transcriptional regulator ABU16_1298 ENOG4108IJ7 Glycine betaine ABU16_1299 ENOG4107SQ8 Glycine betaine ABU16_1306 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) ABU16_1313 ENOG4105EIG urea carboxylase-associated protein 1 ABU16_1314 ENOG4107RA1 nh(3)-dependent nad( ) synthetase ABU16_1315 ENOG4105I1F Resistance protein ABU16_1316 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) ABU16_1317 ENOG41089UC methyltransferase, type 11 ABU16_1318 ENOG4105C5Q Transcriptional regulator ABU16_1319 ENOG4105I82 acetyl xylan esterase ABU16_1320 ENOG410756H nucleotidyltransferase ABU16_1322 ENOG4105C26 Dehydrogenase ABU16_1323 ENOG4105CK7 Sodium proline symporter ABU16_1324 ENOG4107YHD transcriptional regulator ABU16_1326 ENOG4108PJD permease ABU16_1327 ENOG4105U6C Alpha beta hydrolase fold protein ABU16_1329 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) ABU16_1330 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit ABU16_1331 ENOG4108IFG nitrite reductase, (NAD(P)H) ABU16_1332 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) ABU16_1336 ENOG4105S7A ErfK ybiS ycfS ynhG family protein ABU16_1338 ENOG4105CKI cobalamin synthesis protein ABU16_1339 ENOG4105E5Q amino acid AbC transporter ABU16_1340 ENOG4107XKZ Amino acid ABC superfamily ATP binding cassette transporter binding protein ABU16_1341 ENOG4105HHM rdd domain containing protein ABU16_1343 ENOG4105CS2 ec 3.2.1.21 ABU16_1346 ENOG4105C8Q Methyl-accepting chemotaxis ABU16_1347 ENOG41080HJ 6-phospho 3-hexuloisomerase ABU16_1348 ENOG4108VA3 3-hexulose-6-phosphate synthase ABU16_1349 ENOG4105KVH Transcriptional regulator ABU16_1352 ENOG4105CEY Amp-dependent synthetase and ligase ABU16_1358 ENOG4105SX7 Transporter ABU16_1360 ENOG4105W8Z 4'-phosphopantetheinyl transferase ABU16_1362 ENOG4105CDA abc transporter atp-binding protein ABU16_1363 ENOG4105DRP amino acid AbC transporter ABU16_1365 ENOG4106P55 Transcriptional regulator ABU16_1366 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ABU16_1367 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) ABU16_1368 ENOG41069ZX ABU16_1369 ENOG41069ZX ABU16_1371 ENOG4105DUX Transporter ABU16_1374 ENOG4105E1K spore germination protein ABU16_1378 ENOG4107WD8 ABC transporter, permease ABU16_1379 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ABU16_1380 ENOG4105BZU Histidine kinase ABU16_1385 ENOG4105CFH Aspartokinase ABU16_1386 ENOG4105DHS permease protein ABU16_1387 ENOG4105CM4 permease protein ABU16_1388 ENOG4108IPW abc transporter atp-binding protein ABU16_1391 ENOG4105R8C Transcriptional regulator ABU16_1392 ENOG4108DBC nitroreductase ABU16_1393 ENOG41067V3 Antibiotic biosynthesis monooxygenase ABU16_1394 ENOG4105YVS arsR family transcriptional regulator ABU16_1396 ENOG4108JPW Aminotransferase ABU16_1397 ENOG4105C26 Dehydrogenase ABU16_1399 ENOG4105H9W Short-chain dehydrogenase reductase Sdr ABU16_1400 ENOG4105KTB nuclear export factor GLE1 ABU16_1401 ENOG4108T5E Copper resistance protein ABU16_1402 ENOG4108ZYE Transcriptional regulator ABU16_1407 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) ABU16_1408 ENOG4108ZX0 Signal peptidase I ABU16_1413 ENOG4105E7W lamb ycsf family protein ABU16_1414 ENOG4105C5A transporter ABU16_1415 ENOG4105CFM UPF0317 protein ABU16_1416 ENOG4105P4J Allophanate hydrolase, subunit 1 ABU16_1418 ENOG4107258 Transcriptional regulator ABU16_1419 ENOG4105XJB lipolytic protein G-D-S-L family ABU16_1421 ENOG41061CK Antibiotic biosynthesis monooxygenase ABU16_1423 ENOG4107RVG penicillin-binding protein ABU16_1424 ENOG4107QM2 Aldo Keto reductase ABU16_1425 ENOG4105ETD TRANSCRIPTIONal ABU16_1428 ENOG4105HMZ Methyltransferase ABU16_1429 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ABU16_1432 ENOG410606W general stress protein ABU16_1434 ENOG4105VCH membrane ABU16_1436 ENOG4105C9U ATP-dependent DNA helicase RecQ ABU16_1439 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) ABU16_1440 ENOG4107R8N Glycosyl transferase, family 2 ABU16_1442 ENOG4105C0X amino acid ABU16_1446 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) ABU16_1449 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) ABU16_1450 ENOG4105EU9 ABU16_1451 ENOG4105QVS general stress protein ABU16_1452 ENOG41082W1 Cupin 2, conserved barrel domain protein ABU16_1455 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit ABU16_1456 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism ABU16_1457 ENOG4108MRH transcriptional regulatory protein ABU16_1458 ENOG4107QJT sodium dicarboxylate symporter ABU16_1459 ENOG4106F5Q Membrane ABU16_1461 ENOG4105CJ1 ABC, transporter ABU16_1464 ENOG4105FDT acyl-CoA dehydrogenase ABU16_1468 ENOG4105SZ6 Thioredoxin ABU16_1469 ENOG4105CPF Cell wall formation (By similarity) ABU16_1470 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) ABU16_1471 ENOG4105C1J atp-dependent rna helicase ABU16_1472 ENOG410905X membrane-flanked domain protein ABU16_1473 ENOG4105CKV Membrane ABU16_1475 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) ABU16_1476 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein ABU16_1477 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ABU16_1479 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) ABU16_1480 ENOG4107MMM Anti-sigma-factor antagonist ABU16_1481 ENOG4105FUA antagonist ABU16_1482 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase ABU16_1483 ENOG4107SGM protein serine threonine phosphatase ABU16_1484 ENOG4105WN5 stage II sporulation protein ABU16_1485 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) ABU16_1487 ENOG41064BQ Phosphatase ABU16_1491 ENOG4105M5P UPF0310 protein ABU16_1492 ENOG4105RV9 Transcriptional regulator ABU16_1496 ENOG4105DEN Luciferase family ABU16_1499 ENOG4108W2Y isochorismatase ABU16_1500 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein ABU16_1501 ENOG4108HH4 Major Facilitator Superfamily ABU16_1505 ENOG4108V4B ThiJ pfpI ABU16_1506 ENOG4105VEQ Cold shock protein ABU16_1507 ENOG4108VJ1 Transcriptional regulator (CarD family ABU16_1510 ENOG4108MCI Transcriptional regulator, ARAC family ABU16_1511 ENOG4108UZ3 Transporter ABU16_1512 ENOG41086D8 Transcriptional regulator ABU16_1513 ENOG4107U9B transcriptional regulator ABU16_1514 ENOG4105DXI Major Facilitator superfamily ABU16_1516 ENOG4105CZ9 Domain of unknown function (DU1801) ABU16_1517 ENOG4105GIG ABU16_1519 ENOG4105T38 integral membrane protein ABU16_1520 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABU16_1521 ENOG4108ZMQ domain protein ABU16_1522 ENOG4105MJ9 esterase ABU16_1523 ENOG4107Z6X Transcriptional regulator ABU16_1525 ENOG4105KVH Transcriptional regulator ABU16_1526 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein ABU16_1527 ENOG4105EQ0 Major Facilitator superfamily ABU16_1528 ENOG4108JGH Tetr family transcriptional regulator ABU16_1530 ENOG41082YX Transcriptional regulator, arsr family ABU16_1531 ENOG4107R5R arsenical pump membrane protein ABU16_1533 ENOG4105Z7P Acetyltransferase (GNAT) family ABU16_1534 ENOG4107Y9U Membrane ABU16_1536 ENOG4108SQ9 flavin reductase domain protein, FMN-binding ABU16_1537 ENOG4108ZHR arsR family transcriptional regulator ABU16_1538 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) ABU16_1540 ENOG4105ENE Histidine kinase ABU16_1541 ENOG4108VB1 regulatoR ABU16_1542 ENOG4105EYF MMPL domain protein ABU16_1544 ENOG4108WC5 Alpha Beta Hydrolase Fold protein ABU16_1545 ENOG4108UQV Membrane ABU16_1546 ENOG4108Z5V transcriptional regulator, merr family ABU16_1547 ENOG41076HS cation diffusion facilitator family transporter ABU16_1548 ENOG4108TVJ Nitroreductase ABU16_1549 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase ABU16_1550 ENOG4108VGI doxx family ABU16_1551 ENOG4105XXY Thioredoxin ABU16_1558 ENOG410900G Protein of unknown function (DUF421) ABU16_1559 ENOG4108QY0 Membrane ABU16_1563 ENOG4105PF9 Transcriptional regulator ABU16_1565 ENOG4105WQG acetyltransferase ABU16_1567 ENOG4105C85 amino acid ABU16_1570 ENOG41062A4 Transcriptional regulator ABU16_1571 ENOG4105EYF MMPL domain protein ABU16_1572 ENOG4108TVJ Nitroreductase ABU16_1573 ENOG4105FS7 Transcriptional regulator ABU16_1574 ENOG4105C2C drug resistance transporter, Bcr CflA ABU16_1576 ENOG4105DRR Transcriptional regulator, GntR family ABU16_1577 ENOG4105VRS hydrolase family 18 ABU16_1580 ENOG4105G6Z alkaline phosphatase ABU16_1581 ENOG4108ZMX Domain of unknown function (DU1801) ABU16_1583 ENOG4108YM7 Gcn5-related n-acetyltransferase ABU16_1584 ENOG4107TVP HD domain protein ABU16_1586 ENOG41090UD (LipO)protein ABU16_1587 ENOG4105F27 Major Facilitator ABU16_1588 ENOG4105VZJ PTS System ABU16_1589 ENOG4105VCP PTS System ABU16_1590 ENOG4105CK1 PTS System ABU16_1591 ENOG4105CS2 ec 3.2.1.21 ABU16_1592 ENOG4108TZY GntR Family Transcriptional Regulator ABU16_1593 ENOG4105EVU fructokinase ABU16_1594 ENOG4105DG6 mannose-6-phosphate isomerase ABU16_1595 ENOG4105D3P Mannan endo-1,4-beta-mannosidase ABU16_1597 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) ABU16_1598 ENOG4105K8N protein family UPF0079, ATPase ABU16_1599 ENOG41072GX Peptidase M22 Glycoprotease ABU16_1600 ENOG410801F ribosomal-protein-alanine acetyltransferase ABU16_1601 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) ABU16_1602 ENOG4105C5H ABC transporter ABU16_1603 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) ABU16_1604 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) ABU16_1605 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) ABU16_1606 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) ABU16_1608 ENOG4108TYN CAAX amino terminal protease family protein ABU16_1609 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) ABU16_1610 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) ABU16_1613 ENOG4105DVF Cytosine-specific methyltransferase ABU16_1614 ENOG4107RHI Cytosine-specific methyltransferase ABU16_1622 ENOG4105PGZ NB-ARC domain ABU16_1623 ENOG4105CPQ Dehydrogenase ABU16_1624 ENOG4105CT4 transporter ABU16_1626 ENOG41087YS Phage shock protein A ABU16_1627 ENOG4105DQX Zinc finger domain ABU16_1628 ENOG4108WV1 Pfam:DUF477 ABU16_1630 ENOG4108ZMR Ion transport 2 domain-containing protein ABU16_1632 ENOG4107QNK )-transporter ABU16_1638 ENOG4107YUH hydrolase ABU16_1640 ENOG4107STQ Multicopper oxidase ABU16_1641 ENOG4105C85 amino acid ABU16_1643 ENOG4105C7R Atpase associated with various cellular activities aaa_3 ABU16_1648 ENOG4105C7N Xanthine uracil vitamin C permease ABU16_1653 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) ABU16_1654 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit ABU16_1655 ENOG4105C83 adenylosuccinate lyase ABU16_1656 ENOG4105C8V SAICAR synthetase ABU16_1657 ENOG4105VR9 phosphoribosylformylglycinamidine synthase ABU16_1658 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I ABU16_1659 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii ABU16_1661 ENOG4105CXB phosphoribosylaminoimidazole synthetase ABU16_1662 ENOG4108V3E phosphoribosylglycinamide formyltransferase ABU16_1663 ENOG4105DC1 bifunctional purine biosynthesis protein purh ABU16_1664 ENOG4105C12 Phosphoribosylglycinamide synthetase ABU16_1666 ENOG4105DVH amino acid ABU16_1669 ENOG4108R5T secreted protein ABU16_1670 ENOG4105KGF protein, YerC YecD ABU16_1671 ENOG4105CBC glutamate synthase ABU16_1673 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) ABU16_1674 ENOG4105C4R Atp-dependent dna helicase ABU16_1675 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) ABU16_1677 ENOG4105CRN Aminoglycoside phosphotransferase ABU16_1678 ENOG4105KT7 mgtC SapB transporter ABU16_1679 ENOG4105CK7 Sodium proline symporter ABU16_1680 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) ABU16_1681 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) ABU16_1682 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) ABU16_1683 ENOG4108IG5 Transcriptional regulator ABU16_1685 ENOG4105CBD Diacylglycerol kinase ABU16_1686 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) ABU16_1689 ENOG4105D85 methylase ABU16_1690 ENOG4105F6A helicase ABU16_1691 ENOG4105ECI YeeC-like protein ABU16_1701 ENOG4105CDY transcriptional regulatory protein ABU16_1703 ENOG4105M4P Tetr family transcriptional regulator ABU16_1704 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein ABU16_1705 ENOG4107S9F NmrA family ABU16_1708 ENOG4105WEF catalase ABU16_1709 ENOG4105M18 -acetyltransferase ABU16_1714 ENOG4105C2F Histidine kinase ABU16_1715 ENOG4105EQD regulatoR ABU16_1716 ENOG410769Z extracellular solute-binding protein family 1 ABU16_1717 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component ABU16_1718 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component ABU16_1719 ENOG4105F5H Glycosyl Hydrolase Family 88 ABU16_1720 ENOG4105CX8 fg-gap repeat protein ABU16_1721 ENOG41061H0 Monooxygenase ABU16_1722 ENOG4108R1P ABU16_1723 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) ABU16_1725 ENOG4105E0M Sulfatase ABU16_1727 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase ABU16_1729 ENOG41090R9 glycosyltransferase ABU16_1730 ENOG4107R51 Glycosyl transferase, family 2 ABU16_1731 ENOG41090R9 glycosyltransferase ABU16_1732 ENOG4105EU0 Major facilitator Superfamily ABU16_1733 ENOG4105EU0 Major facilitator Superfamily ABU16_1735 ENOG4105CUB amino acid ABU16_1736 ENOG4105C26 Dehydrogenase ABU16_1737 ENOG4105FKZ Methyl-accepting chemotaxis ABU16_1738 ENOG4105C5H ABC transporter ABU16_1740 ENOG4107SWG transcriptional regulator MERR family ABU16_1741 ENOG4105DXB Major Facilitator superfamily ABU16_1744 ENOG4105C5H ABC transporter ABU16_1745 ENOG4105FDU atp-dependent rna helicase ABU16_1747 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein ABU16_1750 ENOG4105E6M Sulphatase-modifying factor protein ABU16_1752 ENOG4105E0A ABC, transporter ABU16_1753 ENOG4108U1V ABC transporter, permease ABU16_1754 ENOG4105DQ5 transport system permease protein ABU16_1755 ENOG4108HUF Transporter ABU16_1758 ENOG4108J20 pectate lyase ABU16_1759 ENOG4107QPK )-transporter ABU16_1761 ENOG4108MRH transcriptional regulatory protein ABU16_1767 ENOG410855V Acylphosphatase ABU16_1768 ENOG4108RPX mosc domain containing protein ABU16_1772 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) ABU16_1777 ENOG4105GEU Spore germination protein ABU16_1779 ENOG4108Q5U germination protein, ger(x)c family ABU16_1780 ENOG4105E1K spore germination protein ABU16_1781 ENOG4105C5Y PTS System ABU16_1782 ENOG4105CG3 alpha amylase, catalytic region ABU16_1783 ENOG4107414 GntR family transcriptional regulator ABU16_1784 ENOG4108RCM Nitroreductase ABU16_1785 ENOG4105CGH 5'-nucleotidase ABU16_1786 ENOG4107RKG DJ-1/PfpI family ABU16_1790 ENOG4105KJF protein tyrosine phosphatase ABU16_1792 ENOG4107U9T Pfam:Ribonuclease_BN ABU16_1793 ENOG4108ISG Major Facilitator ABU16_1795 ENOG4105UPD Calcium Proton ABU16_1797 ENOG4105D8X mechanosensitive ion channel ABU16_1801 ENOG4106KE4 Dehydrogenase ABU16_1802 ENOG4105D7N magnesium and cobalt transport protein CorA ABU16_1804 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) ABU16_1808 ENOG4107RUY (E1 component), alpha subunit ABU16_1810 ENOG4107QKR Dehydrogenase ABU16_1812 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family ABU16_1813 ENOG41069DP small acid-soluble spore protein ABU16_1814 ENOG4105KK4 UPF0060 membrane protein ABU16_1820 ENOG4105F8D glycoside hydrolase family 4 ABU16_1821 ENOG4108Q3X Transcriptional regulator ABU16_1822 ENOG4105CI1 PTS System ABU16_1823 ENOG4105BZ1 (ABC) transporter ABU16_1824 ENOG4105BZ1 (ABC) transporter ABU16_1826 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase ABU16_1827 ENOG4105ID8 Transcriptional regulator, ARAC family ABU16_1828 ENOG4107QNK )-transporter ABU16_1829 ENOG4107QP6 Xylose isomerase domain protein TIM barrel ABU16_1830 ENOG4105CIB oxidoreductase Domain protein ABU16_1832 ENOG4105BZU Histidine kinase ABU16_1833 ENOG4105WH1 Two component transcriptional regulator luxr family ABU16_1835 ENOG4105CJ1 ABC, transporter ABU16_1836 ENOG41090VJ ABC-2 type transporter ABU16_1837 ENOG4108KYE ABC-2 type transporter ABU16_1838 ENOG4105U3E Transcriptional regulator ABU16_1839 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold ABU16_1840 ENOG4105H93 Acyltransferase family ABU16_1841 ENOG4105YA8 Transcriptional regulator ABU16_1842 ENOG4107Y80 Major Facilitator superfamily ABU16_1843 ENOG4108YYS metal-dependent hydrolase (By similarity) ABU16_1844 ENOG4105C0R drug resistance transporter emrb qaca subfamily ABU16_1845 ENOG410834F Transcriptional regulator ABU16_1847 ENOG4108MES Periplasmic binding protein ABU16_1848 ENOG4105DQ5 transport system permease protein ABU16_1849 ENOG4108IHU transport system permease protein ABU16_1850 ENOG4105JAB phenazine biosynthesis protein, phzf family ABU16_1851 ENOG4107Y03 Nitroreductase ABU16_1854 ENOG4105ECP epimerase ABU16_1857 ENOG4105F27 Major Facilitator ABU16_1861 ENOG4106AKJ ABU16_1862 ENOG4105D74 hydrolase ABU16_1864 ENOG4105CKK Glycosyl transferase, family 2 ABU16_1865 ENOG4105EJV Membrane ABU16_1866 ENOG41067AE Membrane-bound metal-dependent hydrolase ABU16_1867 ENOG4105CEN a g-specific adenine glycosylase ABU16_1868 ENOG4106BXE ABU16_1869 ENOG4105CAN Short-chain dehydrogenase reductase Sdr ABU16_1872 ENOG4105EVI UPF0374 protein ABU16_1873 ENOG4105BZ1 (ABC) transporter ABU16_1874 ENOG4107NBY Membrane ABU16_1876 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ABU16_1877 ENOG4105G5W regulator Fur family ABU16_1880 ENOG4108N23 SpoOM-related protein ABU16_1883 ENOG4105EC3 peptidase S51, dipeptidase E ABU16_1885 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) ABU16_1886 ENOG4105DNP FAD linked oxidase domain protein ABU16_1889 ENOG4105E2Y ABC, transporter ABU16_1890 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein ABU16_1891 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component ABU16_1892 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) ABU16_1894 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) ABU16_1895 ENOG4107D63 ABU16_1896 ENOG4105VZ8 Transcriptional regulator ABU16_1898 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) ABU16_1900 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) ABU16_1905 ENOG4105CYN Serine protein kinase ABU16_1906 ENOG4106AKX UPF0229 protein ABU16_1907 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes ABU16_1908 ENOG4105CW7 secretion protein, HlyD family ABU16_1909 ENOG4105C0R drug resistance transporter emrb qaca subfamily ABU16_1910 ENOG4105CS1 NAD(P)H quinone oxidoreductase ABU16_1914 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family ABU16_1915 ENOG4105CZV ABC transporter ABU16_1916 ENOG4105CJ1 ABC, transporter ABU16_1917 ENOG4108TU7 Inherit from COG: (ABC) transporter ABU16_1918 ENOG4105VEQ Cold shock protein ABU16_1920 ENOG4105BZU Histidine kinase ABU16_1927 ENOG4108YBP pseudouridine synthase ABU16_1929 ENOG41080XP Cbs domain ABU16_1930 ENOG4107YBY Hydrolase ABU16_1931 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase ABU16_1933 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ABU16_1934 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator ABU16_1936 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) ABU16_1937 ENOG4105C6V Glycerol-3-phosphate dehydrogenase ABU16_1939 ENOG4105BZU Histidine kinase ABU16_1940 ENOG4105WH1 Two component transcriptional regulator luxr family ABU16_1947 ENOG4105ED1 spovr family ABU16_1948 ENOG4105G6Z alkaline phosphatase ABU16_1951 ENOG4105BZN citrate synthase ABU16_1952 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ABU16_1953 ENOG4105CUB amino acid ABU16_1954 ENOG4105C8J )-transporter ABU16_1955 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABU16_1958 ENOG4105J37 ABU16_1959 ENOG4108AEY RNA polymerase sigma factor ABU16_1960 ENOG4108FN7 Aldo keto reductase ABU16_1961 ENOG4105F6E Acyl-transferase ABU16_1962 ENOG4105C37 (CBS) domain ABU16_1964 ENOG4105CHM Aminotransferase ABU16_1966 ENOG4105C37 (CBS) domain ABU16_1968 ENOG4105WMR Protein CrcB homolog ABU16_1969 ENOG4108QXE glycerophosphoryl diester phosphodiesterase ABU16_1971 ENOG4105D64 Mechanosensitive ion channel ABU16_1972 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) ABU16_1973 ENOG4107VMI polysaccharide deacetylase ABU16_1974 ENOG4105F0I Aminotransferase ABU16_1978 ENOG4105BZ1 (ABC) transporter ABU16_1979 ENOG4105BZ1 (ABC) transporter ABU16_1984 ENOG410839P ABU16_1986 ENOG4106MP8 UPF0754 membrane protein ABU16_1987 ENOG4105WZB UPF0342 protein ABU16_1988 ENOG4105F1N DNA alkylation repair ABU16_1990 ENOG4105D4P Coproporphyrinogen iii oxidase ABU16_1991 ENOG4107S91 Sodium hydrogen exchanger ABU16_1992 ENOG4105NCW Trka-c domain protein ABU16_1994 ENOG4105CGU Enoyl-CoA hydratase ABU16_1996 ENOG4108IUX (ABC) transporter ABU16_1997 ENOG4105RHA ABC transporter, permease ABU16_1998 ENOG4107VRP DNA repair exonuclease ABU16_1999 ENOG4106D4I domain protein ABU16_2000 ENOG4105EQI Metal Dependent Phosphohydrolase ABU16_2002 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) ABU16_2009 ENOG4105NBU tryptophan transport protein ABU16_2010 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) ABU16_2011 ENOG4105K59 histidine triad (HIT) protein ABU16_2018 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation ABU16_2019 ENOG4105BZ4 penicillin-binding protein ABU16_2020 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) ABU16_2021 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) ABU16_2022 ENOG4105C1Q protoporphyrinogen oxidase ABU16_2024 ENOG4105ECB domain protein ABU16_2026 ENOG41090T1 Membrane ABU16_2028 ENOG4105DER m42 family ABU16_2031 ENOG4106AXD ABU16_2032 ENOG4108RQ5 Beta-lactamase domain-containing protein ABU16_2033 ENOG4105DF9 Lipoate-protein, ligase ABU16_2035 ENOG4105CEY Amp-dependent synthetase and ligase ABU16_2037 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 ABU16_2040 ENOG4105KD7 acetyltransferase ABU16_2043 ENOG4108HUF Transporter ABU16_2044 ENOG4107TB6 phosphoglycerate mutase ABU16_2046 ENOG4107F3J Amp-dependent synthetase and ligase ABU16_2047 ENOG4107ZYJ bioY protein ABU16_2048 ENOG4106YBV Methyl-accepting chemotaxis ABU16_2052 ENOG4105XVF Competence transcription factor ABU16_2053 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ABU16_2055 ENOG4105X3H Excalibur domain protein ABU16_2056 ENOG4105E1V na solute symporter ABU16_2057 ENOG4106CAD Protein of unknown function (DUF3311) ABU16_2058 ENOG41060YP ABU16_2061 ENOG4107SCK Monooxygenase ABU16_2062 ENOG4108INS Transcriptional regulator ABU16_2065 ENOG4105TRI Hydrolase ABU16_2068 ENOG4108KK1 membrane protein AbrB duplication ABU16_2069 ENOG4106K7D Major facilitator family transporter ABU16_2070 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) ABU16_2074 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation ABU16_2076 ENOG4105EYH Exonuclease ABU16_2087 ENOG4105ERH Fumarylacetoacetate hydrolase ABU16_2089 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin ABU16_2091 ENOG4105CAQ asparagine synthetase ABU16_2094 ENOG4105UQX Mate efflux family protein ABU16_2095 ENOG4106HBX Transcriptional Regulator AraC Family ABU16_2096 ENOG4105ETE Transcriptional regulator (LacI family ABU16_2097 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) ABU16_2098 ENOG4105SF0 DinB family ABU16_2099 ENOG4108ZUB Lysine exporter protein (Lyse ygga) ABU16_2100 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABU16_2101 ENOG4105MYW Pentapeptide repeat protein ABU16_2102 ENOG4107S9D Alpha beta hydrolase ABU16_2103 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) ABU16_2104 ENOG4107RIQ Sulfate adenylate transferase ABU16_2105 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) ABU16_2106 ENOG4108N5B 2-phosphosulfolactate phosphatase ABU16_2107 ENOG41061P3 phosphosulfolactate synthase ABU16_2109 ENOG4105DIA mandelate racemase muconate lactonizing ABU16_2110 ENOG4107RCC Major Facilitator Superfamily ABU16_2111 ENOG4108SZE gCN5-related N-acetyltransferase ABU16_2112 ENOG4105MA6 gCN5-related N-acetyltransferase ABU16_2115 ENOG4108VPT UPF0234 protein ABU16_2116 ENOG4105QNR S1 RNA binding domain protein ABU16_2120 ENOG4105K7K Transcriptional regulator ABU16_2122 ENOG410751J ABU16_2123 ENOG4105D4Y metalloprotease ABU16_2124 ENOG4105EPR degv family ABU16_2125 ENOG4107AYK membrAne ABU16_2127 ENOG41073B9 ABU16_2128 ENOG4108KP7 hydrolase ABU16_2129 ENOG4108MXZ Esterase ABU16_2130 ENOG4105VG1 fes assembly suf system protein ABU16_2132 ENOG4105IQ5 FAD linked oxidase domain protein ABU16_2134 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase ABU16_2137 ENOG4105C8Y Acetylornithine aminotransferase ABU16_2138 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain ABU16_2140 ENOG4105DBV ornithine carbamoyltransferase ABU16_2146 ENOG4107RMD Basic membrane lipoprotein ABU16_2149 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) ABU16_2150 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) ABU16_2152 ENOG4105C3U ABC transporter ABU16_2153 ENOG4108JQ7 (ABC) transporter ABU16_2156 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ABU16_2158 ENOG4105C31 Tryptophanyl-tRNA synthetase ABU16_2159 ENOG4108J59 Extracellular solute-binding protein, family 5 ABU16_2160 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ABU16_2164 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) ABU16_2165 ENOG4108ZCF integral membrane protein ABU16_2166 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis ABU16_2169 ENOG4105DPN Oligoendopeptidase f ABU16_2171 ENOG4105T58 Dithiol-disulfide isomerase ABU16_2172 ENOG4108Z18 K06886 hemoglobin ABU16_2173 ENOG4105E4C Lytic transglycosylase catalytic ABU16_2174 ENOG4105MIX Adenylate cyclase ABU16_2177 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) ABU16_2178 ENOG4105EMS pseudouridine synthase ABU16_2179 ENOG4105EMS pseudouridine synthase ABU16_2182 ENOG4105ETU transcriptional activator (TenA ABU16_2183 ENOG4108VEU Thiamine monophosphate synthase ABU16_2186 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) ABU16_2187 ENOG4105D06 uba thif-type nad fad binding protein ABU16_2188 ENOG4105DWF phosphomethylpyrimidine kinase ABU16_2189 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH ABU16_2190 ENOG4107A88 ABU16_2202 ENOG4105ENA helicase ABU16_2205 ENOG4108ZMI UPF0477 protein ABU16_2208 ENOG4105C28 cystathionine ABU16_2209 ENOG4105C28 cystathionine ABU16_2210 ENOG4105D9U N-acetyltransferase ABU16_2211 ENOG4105JHY Membrane ABU16_2215 ENOG4106BHF ABU16_2225 ENOG4108PSK reductase ABU16_2228 ENOG4105DM4 PTS System ABU16_2229 ENOG4105DG6 mannose-6-phosphate isomerase ABU16_2230 ENOG4105G7B Protein of unknown function (DUF2992) ABU16_2231 ENOG4105VMI -acetyltransferase ABU16_2232 ENOG4108Z66 YbaK ebsC protein ABU16_2236 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) ABU16_2238 ENOG4108ZJ4 polysaccharide deacetylase ABU16_2239 ENOG4107CUJ Protein of unknown function (DUF2690) ABU16_2245 ENOG4108IEG Formate dehydrogenase Alpha subunit ABU16_2250 ENOG4106A3M Cytochrome p-450 ABU16_2251 ENOG41087PP glycosyltransferase MGT family ABU16_2253 ENOG4105EXQ uroporphyrinogen iii synthase hem4 ABU16_2254 ENOG4105C4B ABC transporter, permease ABU16_2255 ENOG4108IXI (ABC) transporter ABU16_2257 ENOG4105Q95 Cupin 2, conserved barrel domain protein ABU16_2261 ENOG4105D2H Uronic isomerase ABU16_2262 ENOG4105CT4 transporter ABU16_2263 ENOG4105DG4 malate L-lactate dehydrogenase ABU16_2264 ENOG4105CPQ Dehydrogenase ABU16_2265 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) ABU16_2266 ENOG4105DMW Dehydrogenase reductase ABU16_2267 ENOG4108I5G Major Facilitator superfamily ABU16_2268 ENOG4107KJX Transcriptional regulator ABU16_2269 ENOG4107QZW Altronate oxidoreductase ABU16_2270 ENOG4105CTX dehydratase ABU16_2271 ENOG4107TSN permease ABU16_2273 ENOG4105JD4 ATPase yjob ABU16_2276 ENOG41068K0 YCII-related domain ABU16_2277 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase ABU16_2278 ENOG4105KWG Pfam:DUF1696 ABU16_2279 ENOG4105K7W phage-related replication protein ABU16_2280 ENOG4105WEF catalase ABU16_2281 ENOG410635T phage-like element pbsx protein ABU16_2291 ENOG4108TFU terminase (Small subunit) ABU16_2292 ENOG4105IG6 Phage terminase, large subunit ABU16_2293 ENOG4108MDF Phage Portal Protein ABU16_2298 ENOG41060SN ABU16_2301 ENOG4105PQS phage protein ABU16_2302 ENOG4105FR7 XkdM protein, phage-like element PBSX ABU16_2303 ENOG4105MTC XkdN-like protein ABU16_2304 ENOG4108FKH Transglycosylase SLT domain ABU16_2305 ENOG4108WZM domain protein ABU16_2306 ENOG4105X7F ABU16_2308 ENOG4105MFU Protein of unknown function (DUF2634) ABU16_2309 ENOG41066EA baseplate J family protein ABU16_2310 ENOG410906S phage-like element pbsx protein xkdt ABU16_2312 ENOG41068G1 ABU16_2318 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase ABU16_2322 ENOG4105CJ3 phosphate transporter ABU16_2323 ENOG4107GRR phosphate transport regulator ABU16_2324 ENOG4107R7I amino acid ABU16_2326 ENOG4105EDW glycosyl transferase, family 39 ABU16_2327 ENOG4105CKK Glycosyl transferase, family 2 ABU16_2329 ENOG4105C0H protease ABU16_2331 ENOG4108ME1 Peptidase M55 D-aminopeptidase ABU16_2332 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ABU16_2333 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ABU16_2334 ENOG4105C3U ABC transporter ABU16_2337 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A ABU16_2338 ENOG4105DTQ mandelate racemase muconate lactonizing ABU16_2339 ENOG4107SN7 NLP P60 protein ABU16_2340 ENOG4108JQ7 (ABC) transporter ABU16_2341 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) ABU16_2342 ENOG4107TUM Amidinotransferase ABU16_2343 ENOG4108S4H thioesterase Superfamily protein ABU16_2344 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ABU16_2348 ENOG4108428 Inherit from COG: -acetyltransferase ABU16_2350 ENOG41080TC multidrug resistance protein ABU16_2351 ENOG4105CIY formyltetrahydrofolate deformylase ABU16_2352 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) ABU16_2355 ENOG4105K56 Transcriptional regulator ABU16_2356 ENOG4108ZHJ Organic hydroperoxide resistance protein ABU16_2358 ENOG4107Y2X deaminase ABU16_2359 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) ABU16_2361 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin ABU16_2364 ENOG4108W7F transporter, permease ABU16_2365 ENOG4108JJB ABC transporter ABU16_2366 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein ABU16_2367 ENOG4108X43 YKOF domain protein ABU16_2368 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ABU16_2369 ENOG41062D9 Histidine kinase ABU16_2371 ENOG4106849 propeptide, pepSY amd peptidase M4 ABU16_2373 ENOG4105CJW magnesium transporter ABU16_2374 ENOG4105V75 Transcriptional regulator ABU16_2383 ENOG4105DQE DNA ligase ABU16_2384 ENOG4105FDF Could be involved in DNA repair (By similarity) ABU16_2385 ENOG4105BZU Histidine kinase ABU16_2386 ENOG4107T5V SNARE associated Golgi ABU16_2388 ENOG4107TS3 membrane protein, TerC ABU16_2389 ENOG4108WZW RNA polymerase sigma ABU16_2391 ENOG410681C small acid-soluble spore protein ABU16_2393 ENOG4105D0M Protease HtpX homolog ABU16_2397 ENOG4108TGC Acyltransferase ABU16_2398 ENOG4105BZU Histidine kinase ABU16_2399 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ABU16_2401 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) ABU16_2402 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) ABU16_2403 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase ABU16_2405 ENOG4107T6J Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit ABU16_2406 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) ABU16_2407 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) ABU16_2408 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) ABU16_2412 ENOG4105BZU Histidine kinase ABU16_2413 ENOG41090MY MarR family Transcriptional regulator ABU16_2414 ENOG4105ER2 Ompa motb domain protein ABU16_2415 ENOG4105E14 MotA TolQ exbB proton channel ABU16_2417 ENOG4108K88 Membrane ABU16_2418 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) ABU16_2419 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase ABU16_2420 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) ABU16_2421 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) ABU16_2424 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr ABU16_2425 ENOG4105FEA Spore maturation protein ABU16_2434 ENOG4105F0V Cell wall hydrolase ABU16_2437 ENOG4105C59 p-type ATPase ABU16_2439 ENOG4105DC7 peptidase M24 ABU16_2442 ENOG4105CID antiterminator ABU16_2444 ENOG4105KRI phosphocarrier protein (HPr ABU16_2445 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) ABU16_2447 ENOG4105F6S Spore photoproduct lyase ABU16_2449 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer ABU16_2450 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ABU16_2451 ENOG4105K4I Scp-like extracellular ABU16_2453 ENOG4105BZU Histidine kinase ABU16_2454 ENOG4105CHM Aminotransferase ABU16_2456 ENOG4107R88 Chemotaxis protein (CheV) ABU16_2457 ENOG4105UIN ABU16_2459 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein ABU16_2461 ENOG4105K6S Short-chain dehydrogenase reductase Sdr ABU16_2462 ENOG4105ESF Peptidoglycan binding domain protein ABU16_2463 ENOG4105ESF Peptidoglycan binding domain protein ABU16_2465 ENOG4105EPM Diguanylate phosphodiesterase ABU16_2467 ENOG4107IN1 Protein of unknown function (DUF1797) ABU16_2468 ENOG4108XRC Protein of unknown function (DUF458) ABU16_2474 ENOG4105NQC Flavodoxin ABU16_2476 ENOG4105CH2 amidohydrolase ABU16_2478 ENOG4105D8X mechanosensitive ion channel ABU16_2479 ENOG4105D3R alkyl hydroperoxide reductase ABU16_2480 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ABU16_2483 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) ABU16_2484 ENOG4105D06 uba thif-type nad fad binding protein ABU16_2485 ENOG4105CVM Molybdenum cofactor synthesis domain protein ABU16_2486 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein ABU16_2487 ENOG4108ZAF Molybdopterin ABU16_2488 ENOG41067WU Molybdopterin converting factor (Subunit 1) ABU16_2489 ENOG4105BZ1 (ABC) transporter ABU16_2490 ENOG4105BZ1 (ABC) transporter ABU16_2492 ENOG4107X8C Efflux transporter RND family MFP subunit ABU16_2493 ENOG4105C19 ABC transporter ABU16_2494 ENOG4107RBB ABC transporter, permease ABU16_2495 ENOG4105E98 transcriptional regulator DeoR family ABU16_2496 ENOG4105DE4 1-phosphofructokinase ABU16_2497 ENOG4105DM4 PTS System ABU16_2498 ENOG4105C3F Signal peptidase i ABU16_2500 ENOG4105C5H ABC transporter ABU16_2501 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) ABU16_2506 ENOG4105BZU Histidine kinase ABU16_2508 ENOG4107ZYR domain protein ABU16_2510 ENOG4105CN5 Metallo-Beta-Lactamase ABU16_2513 ENOG4108X4Q Hydrolase ABU16_2514 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) ABU16_2518 ENOG4105CPP Dehydrogenase, E1 component ABU16_2519 ENOG4105C7S Dehydrogenase ABU16_2520 ENOG4107QN2 dihydrolipoyl dehydrogenase ABU16_2523 ENOG4105CXN decarboxylase ABU16_2524 ENOG4105WBI UPF0223 protein ABU16_2528 ENOG4105ECY inositol monophosphatase ABU16_2530 ENOG4105JQZ Methyltransferase ABU16_2539 ENOG4105CI3 gtp-binding protein typa ABU16_2540 ENOG4105QA2 ABU16_2543 ENOG4108IAB Phoh family ABU16_2545 ENOG4105CSV Glutaminase ABU16_2546 ENOG4105ZPI UPF0358 protein ABU16_2548 ENOG4105CNI cell division protein FtsW ABU16_2549 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) ABU16_2552 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) ABU16_2555 ENOG4105BZ9 Cytochrome C oxidase, subunit I ABU16_2556 ENOG4105CCU oxidase (Subunit III) ABU16_2557 ENOG41064X9 cytochrome C oxidase subunit IV ABU16_2560 ENOG41080XQ Signal transduction protein with cbs domains ABU16_2561 ENOG4106UY4 Inherit from COG: Scp-like extracellular ABU16_2565 ENOG4105WUC UPF0298 protein ABU16_2566 ENOG4106H78 methyltransferase ABU16_2567 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) ABU16_2568 ENOG4105H20 Sporulation integral membrane protein YlbJ ABU16_2569 ENOG4105D78 K07001 NTE family protein ABU16_2570 ENOG41063PX domain protein ABU16_2571 ENOG4105CDE UPF0348 protein ABU16_2573 ENOG4105KNH Nucleic acid-binding protein ABU16_2579 ENOG4108V6E Cell division protein mraZ ABU16_2580 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) ABU16_2582 ENOG4105CJN penicillin-binding protein ABU16_2583 ENOG4105CJN penicillin-binding protein ABU16_2584 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) ABU16_2585 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) ABU16_2586 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) ABU16_2587 ENOG4105CNI cell division protein FtsW ABU16_2588 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) ABU16_2589 ENOG4105D4A Cell wall formation (By similarity) ABU16_2590 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) ABU16_2591 ENOG4108R2U division initiation protein ABU16_2593 ENOG4105K67 small basic protein ABU16_2594 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) ABU16_2595 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) ABU16_2597 ENOG4105FFI sigma-e processing peptidase spoiiga ABU16_2598 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ABU16_2600 ENOG4105DKW ABC transporter ABU16_2602 ENOG4105WR5 sporulation protein, YlmC YmxH family ABU16_2603 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase ABU16_2604 ENOG4105DFA alanine racemase domain protein ABU16_2605 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) ABU16_2606 ENOG41067XK integral membrane protein ABU16_2607 ENOG4105DBK s4 domain protein ABU16_2610 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) ABU16_2612 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) ABU16_2613 ENOG4105C34 Pseudouridine synthase ABU16_2614 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) ABU16_2616 ENOG4105CXT aspartate transcarbamylase ABU16_2618 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain ABU16_2619 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain ABU16_2620 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) ABU16_2621 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) ABU16_2622 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) ABU16_2623 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) ABU16_2624 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) ABU16_2626 ENOG4107S4M Sulfate adenylate transferase ABU16_2627 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) ABU16_2628 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) ABU16_2629 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein ABU16_2630 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein ABU16_2631 ENOG4105F23 Fibronectin-binding protein ABU16_2633 ENOG4105DSJ YicC domain protein ABU16_2634 ENOG4105KC4 UPF0296 protein ABU16_2635 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) ABU16_2637 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase ABU16_2638 ENOG4105C25 Primosomal protein n' ABU16_2639 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) ABU16_2640 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) ABU16_2641 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B ABU16_2642 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs ABU16_2643 ENOG4108ZF3 Phosphatase ABU16_2644 ENOG4105D9P serine threonine protein kinase ABU16_2645 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) ABU16_2646 ENOG4105DJV ribulose-phosphate 3-epimerase ABU16_2647 ENOG4105FJ0 thiamine ABU16_2648 ENOG4105VB9 50S ribosomal protein l28 ABU16_2649 ENOG4108ZAA Alkaline-shock protein ABU16_2650 ENOG4105DP4 dak2 domain fusion protein ylov ABU16_2652 ENOG4105EJQ L-serine dehydratase ABU16_2653 ENOG4105CB5 ATP-dependent DNA helicase recG ABU16_2654 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) ABU16_2656 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ABU16_2657 ENOG4105CHR reductase ABU16_2658 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) ABU16_2659 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) ABU16_2660 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) ABU16_2661 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ABU16_2663 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) ABU16_2665 ENOG4105K5M 30s ribosomal protein S16 ABU16_2666 ENOG4108BW8 UPF0109 protein ABU16_2668 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) ABU16_2669 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) ABU16_2670 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) ABU16_2671 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) ABU16_2672 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) ABU16_2674 ENOG4105VM1 flagellar ABU16_2675 ENOG4105CMV Succinyl-CoA synthetase subunit beta ABU16_2676 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha ABU16_2677 ENOG4105C79 DNA protecting protein DprA ABU16_2678 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) ABU16_2679 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) ABU16_2680 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ABU16_2681 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) ABU16_2682 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) ABU16_2684 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) ABU16_2685 ENOG4108ZC9 flagellar basal-body rod protein flgc ABU16_2686 ENOG4105VQ0 flagellar hook-basal body complex protein fliE ABU16_2687 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) ABU16_2688 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) ABU16_2691 ENOG4106YF4 Flagellar biosynthesis chaperone ABU16_2693 ENOG410696Y Flagellar hook-length control protein ABU16_2694 ENOG410822I Flagellar hook capping protein ABU16_2695 ENOG4108JQA flagellar ABU16_2696 ENOG41068WV flagellar FlbD family protein ABU16_2698 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) ABU16_2699 ENOG4105DD5 Flagellar motor switch protein ABU16_2700 ENOG4107YTP response regulator receiver protein ABU16_2702 ENOG4105CN7 Flagellar biosynthetic protein FliP ABU16_2703 ENOG4105VS8 Flagellar biosynthetic protein fliq ABU16_2704 ENOG4105D19 Role in flagellar biosynthesis (By similarity) ABU16_2705 ENOG4105D00 flagellar biosynthetic protein flhB ABU16_2706 ENOG4105D7B Flagellar biosynthesis protein flha ABU16_2707 ENOG4105FZW flagellar biosynthesis regulator FlhF ABU16_2709 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) ABU16_2710 ENOG4105CBS Chea signal transduction histidine kinase ABU16_2711 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis ABU16_2714 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ABU16_2716 ENOG4105CE9 30S ribosomal protein S2 ABU16_2717 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) ABU16_2719 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) ABU16_2720 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) ABU16_2721 ENOG4105KNE Phosphatidate cytidylyltransferase ABU16_2723 ENOG4105DZP Membrane-associated zinc metalloprotease ABU16_2724 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) ABU16_2725 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) ABU16_2726 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) ABU16_2727 ENOG4105CHV Transcription elongation factor NusA ABU16_2728 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination ABU16_2729 ENOG4105VHM ribosomal protein ABU16_2730 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) ABU16_2731 ENOG4105W7A Protein of unknown function (DUF503) ABU16_2732 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) ABU16_2733 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) ABU16_2734 ENOG4105DTN riboflavin biosynthesis protein ribF ABU16_2735 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) ABU16_2737 ENOG4105C1V Peptidase, M16 ABU16_2740 ENOG4105E35 Dipicolinate synthase subunit A ABU16_2741 ENOG4108S0H Dipicolinic acid synthetase, b subunit ABU16_2742 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) ABU16_2744 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ABU16_2746 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit ABU16_2748 ENOG4105CNU cell division protein FtsK ABU16_2749 ENOG4105FDP GntR family transcriptional regulator ABU16_2754 ENOG4108RKS Short-chain dehydrogenase reductase Sdr ABU16_2755 ENOG4105XZV Protein of unknown function (DUF3243) ABU16_2758 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase ABU16_2759 ENOG4105CEV competence damage-inducible protein ABU16_2761 ENOG4108A04 Beta-lactamase ABU16_2762 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) ABU16_2763 ENOG4105D48 metallophosphoesterase ABU16_2764 ENOG4105MCT stage V sporulation protein S ABU16_2766 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ABU16_2767 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) ABU16_2770 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) ABU16_2771 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) ABU16_2774 ENOG4105IIP Membrane ABU16_2775 ENOG4105W1N transcriptional regulator ABU16_2776 ENOG4108151 Beta-lactamase domain protein ABU16_2777 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ABU16_2780 ENOG4107QKG PfaD family ABU16_2781 ENOG41062T2 Acyl carrier protein ABU16_2782 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase ABU16_2783 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase ABU16_2784 ENOG4108MGH Enoyl-CoA hydratase ABU16_2785 ENOG4108KQ6 Enoyl-CoA hydratase ABU16_2786 ENOG4105C0W non-ribosomal peptide synthetase ABU16_2787 ENOG4107SQU synthase ABU16_2789 ENOG4105C0W non-ribosomal peptide synthetase ABU16_2791 ENOG4106A3M Cytochrome p-450 ABU16_2794 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin ABU16_2796 ENOG4105K7W phage-related replication protein ABU16_2797 ENOG4108X3M OsmC Ohr family protein ABU16_2798 ENOG410814C multidrug resistance protein ABU16_2802 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) ABU16_2803 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) ABU16_2806 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) ABU16_2807 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ABU16_2808 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ABU16_2809 ENOG4105U6W MutT NUDIX family protein ABU16_2810 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase ABU16_2812 ENOG4106F1P AAA ATPase, central domain protein ABU16_2813 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) ABU16_2814 ENOG4105CXI aluminum resistance protein ABU16_2815 ENOG4105KV4 Transcriptional regulator ABU16_2816 ENOG4105C5F glutamine synthetase ABU16_2820 ENOG4107AUC ABU16_2822 ENOG4108RAV Conserved protein ABU16_2827 ENOG410907G ABU16_2828 ENOG4105CT4 transporter ABU16_2829 ENOG4105DSG hydrolase family 43 ABU16_2830 ENOG4105E2R ROK family ABU16_2831 ENOG4105C93 Xylose Isomerase ABU16_2832 ENOG4105CMG Carbohydrate kinase ABU16_2834 ENOG4107Y9E nuclease ABU16_2835 ENOG4105C54 Major Facilitator superfamily ABU16_2836 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ABU16_2838 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) ABU16_2852 ENOG4108Q8B Spore germination protein ABU16_2853 ENOG4108NHD germination protein ABU16_2856 ENOG4105FVX ABU16_2858 ENOG4105K7W phage-related replication protein ABU16_2860 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) ABU16_2862 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) ABU16_2864 ENOG4108SVB resolvase ABU16_2865 ENOG4105VPS UPF0291 protein ABU16_2866 ENOG4105CV1 Transketolase (EC 2.2.1.1) ABU16_2870 ENOG4107QIV Cytochrome c biogenesis protein ABU16_2875 ENOG4107DZX Small, acid-soluble spore protein P ABU16_2877 ENOG4108I0Z Aconitate hydratase ABU16_2878 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ABU16_2881 ENOG41067CD Small, acid-soluble spore protein Tlp ABU16_2883 ENOG4105MI2 ABU16_2884 ENOG4105W8X HesB YadR YfhF-family protein ABU16_2885 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) ABU16_2886 ENOG4105K4P CoA-binding domain protein ABU16_2887 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABU16_2893 ENOG4107QWR cellulase (EC 3.2.1.4) ABU16_2895 ENOG4108MYR Secreted protein ABU16_2896 ENOG4107SYN Glycosyl hydrolases family 43 ABU16_2898 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ABU16_2899 ENOG4107T5V SNARE associated Golgi ABU16_2901 ENOG4107QX3 carboxylase ABU16_2902 ENOG4105E39 Enoyl-CoA hydratase ABU16_2903 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase ABU16_2904 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit ABU16_2905 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ABU16_2906 ENOG4105CEY Amp-dependent synthetase and ligase ABU16_2907 ENOG4105C1G acyl-Coa dehydrogenase ABU16_2909 ENOG4105F32 YngK protein ABU16_2910 ENOG4106U2H Protein of unknown function (DUF1360) ABU16_2912 ENOG4105CEY Amp-dependent synthetase and ligase ABU16_2913 ENOG4105C0W non-ribosomal peptide synthetase ABU16_2915 ENOG4105C0W non-ribosomal peptide synthetase ABU16_2916 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family ABU16_2917 ENOG4108N2V aldose 1-epimerase ABU16_2918 ENOG4107QJQ Mate efflux family protein ABU16_2922 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) ABU16_2923 ENOG4105SKE transcriptional Regulator LysR family ABU16_2924 ENOG4105CB2 alcohol dehydrogenase ABU16_2925 ENOG4105BZ8 glutamate synthase ABU16_2926 ENOG4105CBC glutamate synthase ABU16_2927 ENOG4105C5Q Transcriptional regulator ABU16_2928 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) ABU16_2929 ENOG4105II7 pyrroline-5-carboxylate reductase ABU16_2933 ENOG4108UB7 ABU16_2934 ENOG41068WN ABU16_2935 ENOG4105IE8 Alpha-ketoglutarate permease ABU16_2936 ENOG4107U6E carbohydrate kinase FGGY ABU16_2937 ENOG4108M3J Dehydrogenase ABU16_2938 ENOG4108J2R molybdopterin oxidoreductase ABU16_2943 ENOG4105EC8 Methyl-accepting chemotaxis ABU16_2946 ENOG4108YQE rare lipoprotein a ABU16_2947 ENOG4105XPP Protein of unknown function (DUF1275) ABU16_2948 ENOG4108NR7 pectate lyase ABU16_2949 ENOG4108RAV Conserved protein ABU16_2951 ENOG4105F0F Oxalate decarboxylase ABU16_2953 ENOG4105EPI acetyltransferase, (GNAT) family ABU16_2956 ENOG41073R8 VanW family ABU16_2958 ENOG4105VMP Transcriptional regulator ABU16_2959 ENOG4105NX3 Membrane ABU16_2961 ENOG4108Q5Y Membrane ABU16_2963 ENOG4108V4B ThiJ pfpI ABU16_2964 ENOG4108J4B Beta-lactamase ABU16_2967 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) ABU16_2968 ENOG4107T94 Endo-14-beta-xylanase ABU16_2969 ENOG4105YB8 TM2 domain containing protein ABU16_2970 ENOG4108IMY Transcriptional regulator ABU16_2973 ENOG4108RAV Conserved protein ABU16_2974 ENOG41079CX ABU16_2979 ENOG410780I phosphoprotein phosphatase activity ABU16_2981 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ABU16_2982 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ABU16_2985 ENOG4105DB4 ABU16_2988 ENOG4106ANW SMI1_KNR4 ABU16_2989 ENOG4106BHF ABU16_2993 ENOG4108Z7R Chaperone CsaA ABU16_2994 ENOG4105FTV AraC Family Transcriptional Regulator ABU16_2995 ENOG4108HJF gCN5-related N-acetyltransferase ABU16_2997 ENOG4108W8B Beta-lactamase domain protein ABU16_2999 ENOG4105D29 Helix-turn-helix type 11 domain protein ABU16_3001 ENOG4105KTU Transcriptional regulator, arsr family ABU16_3003 ENOG4108SJC Membrane ABU16_3008 ENOG4105ECK Fatty Acid Desaturase ABU16_3009 ENOG4108ZGX Histidine kinase ABU16_3010 ENOG4108S01 response regulator ABU16_3011 ENOG41069ER domain protein ABU16_3012 ENOG4105C9U ATP-dependent DNA helicase RecQ ABU16_3015 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) ABU16_3016 ENOG4105SCY DNAK suppressor ABU16_3025 ENOG4105C26 Dehydrogenase ABU16_3026 ENOG4105EWU Squalene--hopene cyclase ABU16_3027 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ABU16_3028 ENOG4105C8J )-transporter ABU16_3029 ENOG4105C09 Bile acid ABU16_3030 ENOG4105C7S Dehydrogenase ABU16_3032 ENOG4107T89 von Willebrand factor, type A ABU16_3033 ENOG4105GMT ATPase associated with various cellular activities aaa_5 ABU16_3035 ENOG4105K4H Nlp p60 protein ABU16_3036 ENOG41087PP glycosyltransferase MGT family ABU16_3038 ENOG4107QMU Mate efflux family protein ABU16_3039 ENOG4106SCS STAS domain ABU16_3043 ENOG4105FR1 rard protein ABU16_3046 ENOG4105C6Z Gluconate ABU16_3047 ENOG41090U3 tautomerase ABU16_3051 ENOG4105FBA Phospholipase Carboxylesterase ABU16_3054 ENOG4105E1V na solute symporter ABU16_3058 ENOG4108VXD carboxy-peptidase ABU16_3059 ENOG4105D3A purine nucleoside phosphorylase DeoD-type ABU16_3062 ENOG4106Z5R ABU16_3063 ENOG410841Q phosphoesterase PA-phosphatase related protein ABU16_3069 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein ABU16_3070 ENOG4108TSC N-acetyltransferase ABU16_3071 ENOG4107S4Y M20 DapE family protein YgeY ABU16_3074 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ABU16_3082 ENOG4107T32 3-phytase (EC 3.1.3.8) ABU16_3083 ENOG4105C5E polysaccharide biosynthesis protein ABU16_3084 ENOG4105E0X reductase ABU16_3085 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) ABU16_3089 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) ABU16_3090 ENOG41090WU lipolytic protein G-D-S-L family ABU16_3091 ENOG4108KF3 Electron transport protein SCO1 SenC ABU16_3093 ENOG4105C7B Threonine dehydratase ABU16_3095 ENOG4108UT2 hemolysin iii ABU16_3097 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) ABU16_3098 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) ABU16_3101 ENOG4107YX5 Pfam:DUF548 ABU16_3102 ENOG4108Y6J UPF0403 protein ABU16_3103 ENOG4105C01 Dihydroxy-acid dehydratase ABU16_3106 ENOG4108V06 Glutathione peroxidase ABU16_3107 ENOG4105CVG Homoserine O-transsuccinylase ABU16_3115 ENOG41081VK Ribonuclease ABU16_3121 ENOG410890F Dynamin family ABU16_3123 ENOG41065KQ synthase ABU16_3124 ENOG4105C2W permease ABU16_3125 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) ABU16_3126 ENOG4105CTD carboxy-peptidase ABU16_3127 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) ABU16_3128 ENOG4108UHU Aldolase ABU16_3129 ENOG4105D7K pfkb domain protein ABU16_3130 ENOG4108M60 Transcriptional regulator ABU16_3132 ENOG4105CHR reductase ABU16_3133 ENOG4105DVT helicase ABU16_3135 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) ABU16_3137 ENOG4108UKS UPF0398 protein ABU16_3139 ENOG4107X2U Inherit from COG: Exonuclease-like protein ABU16_3140 ENOG4108I5C dEAD DEAH box helicase ABU16_3150 ENOG4105BZ4 penicillin-binding protein ABU16_3152 ENOG4105CSM endonuclease III ABU16_3154 ENOG4105C5S asparaginyl-tRNA synthetase ABU16_3155 ENOG4105CHM Aminotransferase ABU16_3157 ENOG4105YAC ABU16_3158 ENOG4105DVT helicase ABU16_3159 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) ABU16_3160 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) ABU16_3161 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) ABU16_3162 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase ABU16_3163 ENOG4105DJ0 Poly(A) Polymerase ABU16_3164 ENOG4105CPK Glycosyl transferase (Group 1 ABU16_3165 ENOG4105FJR Lmbe family ABU16_3166 ENOG4108Z5K methylglyoxal synthase ABU16_3167 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) ABU16_3168 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase ABU16_3169 ENOG4108JYZ YitT family ABU16_3173 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) ABU16_3177 ENOG41068YB TPR repeat-containing protein ABU16_3179 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase ABU16_3181 ENOG4105CIH Imidazole acetol-phosphate transaminase ABU16_3183 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) ABU16_3184 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase ABU16_3186 ENOG4108I0Q anthranilate phosphoribosyltransferase ABU16_3187 ENOG4108I0Q anthranilate phosphoribosyltransferase ABU16_3188 ENOG4105CRQ synthase (Component I) ABU16_3189 ENOG4105KHN chorismate mutase ABU16_3190 ENOG4105D49 3-dehydroquinate synthase ABU16_3191 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase ABU16_3192 ENOG4105BZU Histidine kinase ABU16_3194 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) ABU16_3195 ENOG4105EAH synthase ABU16_3196 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) ABU16_3197 ENOG4105XXQ heptaprenyl diphosphate synthase component I ABU16_3199 ENOG4105EUJ GTP cyclohydrolase i ABU16_3200 ENOG4105K70 DNA-binding protein ABU16_3201 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) ABU16_3204 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase ABU16_3205 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) ABU16_3206 ENOG41065D1 ABU16_3207 ENOG4105S2F ABU16_3210 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) ABU16_3211 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) ABU16_3212 ENOG4105CAT Cytidine monophosphate kinase ABU16_3215 ENOG4105MSI germination protein ypeb ABU16_3217 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) ABU16_3218 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase ABU16_3222 ENOG4107RGJ metallophosphoesterase ABU16_3225 ENOG4105I7S Abortive infection protein ABU16_3226 ENOG4105C9U ATP-dependent DNA helicase RecQ ABU16_3227 ENOG4105T7X ABU16_3229 ENOG4108SAX Membrane ABU16_3231 ENOG4108JQ1 Dehydrogenase ABU16_3232 ENOG4105FF2 Type I DHQase ABU16_3235 ENOG4105BZU Histidine kinase ABU16_3236 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ABU16_3237 ENOG4105CRE cytochrome C ABU16_3238 ENOG4107TWT Cytochrome c biogenesis protein ABU16_3241 ENOG4105FE9 pseudouridine synthase ABU16_3243 ENOG4108JIC nucleoside recognition domain protein ABU16_3244 ENOG4105DZ1 carboxypeptidase ABU16_3246 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) ABU16_3247 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) ABU16_3250 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) ABU16_3251 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) ABU16_3252 ENOG4108R6K riboflavin synthase, subunit alpha ABU16_3253 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) ABU16_3256 ENOG4105C3F Signal peptidase i ABU16_3257 ENOG4105VES Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) ABU16_3261 ENOG4107ZE5 PPIases accelerate the folding of proteins ABU16_3263 ENOG4105PTM secreted protein ABU16_3264 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) ABU16_3266 ENOG4105G6R Stage v sporulation protein ae ABU16_3268 ENOG4105CZ3 stage V sporulation protein ad ABU16_3269 ENOG41090VF Stage v sporulation protein ac ABU16_3272 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ABU16_3273 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) ABU16_3274 ENOG41082AN stage II sporulation protein ABU16_3275 ENOG4105DZ1 carboxypeptidase ABU16_3276 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) ABU16_3277 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) ABU16_3278 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ABU16_3281 ENOG4105I3K Ferric uptake regulator, Fur family ABU16_3282 ENOG4105MZ9 stage II sporulation protein m ABU16_3285 ENOG4105DFD Na H antiporter ABU16_3286 ENOG4108IJ0 Aspartate ammonia-lyase ABU16_3287 ENOG4105HDK L-asparaginase ABU16_3288 ENOG4108IMY Transcriptional regulator ABU16_3290 ENOG4108YZ4 nudix hydrolase ABU16_3292 ENOG4105CPC Aldo Keto reductase ABU16_3297 ENOG4106HZJ ABU16_3298 ENOG4105RHY Pfam:UPF0157 ABU16_3299 ENOG4105KAC Antibiotic biosynthesis monooxygenase ABU16_3300 ENOG4108XET gCN5-related N-acetyltransferase ABU16_3302 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ABU16_3305 ENOG4105E5W Transporter ABU16_3307 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase ABU16_3310 ENOG4108IXY short-chain dehydrogenase reductase ABU16_3311 ENOG41069FQ Metallo-beta-lactamase superfamily ABU16_3312 ENOG4105II7 pyrroline-5-carboxylate reductase ABU16_3314 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABU16_3316 ENOG410861F 50S ribosomal protein L33 ABU16_3317 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) ABU16_3318 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase ABU16_3319 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) ABU16_3320 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ABU16_3322 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) ABU16_3324 ENOG4108NA0 Uncharacterized conserved protein (COG2071) ABU16_3325 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) ABU16_3326 ENOG4108HNZ carboxyl transferase ABU16_3327 ENOG4108ZVT methylmalonyl-coA epimerase ABU16_3328 ENOG4108VZI ErfK ybiS ycfS ynhG family protein ABU16_3329 ENOG4108QEG Membrane ABU16_3330 ENOG4105CDA abc transporter atp-binding protein ABU16_3331 ENOG4105E5Q amino acid AbC transporter ABU16_3332 ENOG4108HW3 (ABC) transporter ABU16_3333 ENOG4108Y6J UPF0403 protein ABU16_3334 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) ABU16_3337 ENOG4105C7S Dehydrogenase ABU16_3338 ENOG4105CPP Dehydrogenase, E1 component ABU16_3341 ENOG4105CKM Branched-chain carboxylic acid kinase ABU16_3342 ENOG4107RDP Dehydrogenase ABU16_3344 ENOG4108JUB Transcriptional regulator ABU16_3345 ENOG4106CCJ Protein of unknown function (DUF2627) ABU16_3346 ENOG4105CR4 methylisocitrate lyase ABU16_3347 ENOG4105DXD 2-methylcitrate dehydratase ABU16_3349 ENOG4105C1G acyl-Coa dehydrogenase ABU16_3350 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ABU16_3352 ENOG4108QXE glycerophosphoryl diester phosphodiesterase ABU16_3353 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase ABU16_3355 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABU16_3357 ENOG4107QQR Sporulation ABU16_3359 ENOG4105S1Z Stage IV sporulation protein B ABU16_3360 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) ABU16_3361 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) ABU16_3362 ENOG4105DX0 Hemolysin A ABU16_3364 ENOG4105CTB Polyprenyl synthetase ABU16_3365 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) ABU16_3366 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) ABU16_3367 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) ABU16_3368 ENOG4105M7K Involved in the transcription termination process (By similarity) ABU16_3369 ENOG4108ZSR alkaline shock protein ABU16_3370 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ABU16_3374 ENOG410644B Stage III sporulation protein af ABU16_3376 ENOG4105KQ4 Stage iii sporulation protein ad ABU16_3377 ENOG4108CQH stage III sporulation protein AC ABU16_3378 ENOG4105KR5 Stage iii sporulation protein ABU16_3379 ENOG4105CD2 stage iii sporulation protein aa ABU16_3381 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) ABU16_3382 ENOG4105DC7 peptidase M24 ABU16_3383 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) ABU16_3385 ENOG4105CBJ Metal-dependent enzyme ABU16_3388 ENOG4105KST dependent repressor ABU16_3389 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) ABU16_3390 ENOG4105WZW rhodanese family ABU16_3391 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor ABU16_3392 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor ABU16_3393 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) ABU16_3394 ENOG4105C0D helicase ABU16_3397 ENOG4108IMY Transcriptional regulator ABU16_3399 ENOG4105VFR signal peptidase ABU16_3412 ENOG4105C37 (CBS) domain ABU16_3416 ENOG4105C5X domain protein ABU16_3421 ENOG4105E0M Sulfatase ABU16_3424 ENOG4107ZXI Rhomboid family ABU16_3426 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase ABU16_3433 ENOG41068DG YceG-like family ABU16_3434 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) ABU16_3435 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) ABU16_3436 ENOG4105E2Z phosphate ABC transporter (Permease ABU16_3437 ENOG4105C8U phosphate abc transporter ABU16_3438 ENOG4105CVA phosphate ABU16_3439 ENOG4107RF6 penicillin-binding protein ABU16_3441 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ABU16_3442 ENOG4105SXS Protein of unknown function (DUF456) ABU16_3445 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) ABU16_3446 ENOG41063Y9 ABU16_3447 ENOG4108U5J '-nucleotidase ABU16_3448 ENOG4105N80 Ferric uptake regulator, Fur family ABU16_3449 ENOG4108JYZ YitT family ABU16_3450 ENOG41069ZM Protein of unknown function (DUF2624) ABU16_3451 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) ABU16_3454 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) ABU16_3455 ENOG4105EGD dinuclear metal center protein, YbgI family ABU16_3459 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ABU16_3460 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) ABU16_3461 ENOG41082VT Uncharacterized BCR, YaiI/YqxD family COG1671 ABU16_3462 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) ABU16_3464 ENOG4105C38 Glycyl-tRNA synthetase beta subunit ABU16_3465 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit ABU16_3466 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) ABU16_3468 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) ABU16_3469 ENOG4105KG3 cytidine deaminase ABU16_3470 ENOG4107YR5 Diacylglycerol kinase ABU16_3471 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) ABU16_3472 ENOG4105CTJ Metal Dependent Phosphohydrolase ABU16_3473 ENOG4105C9A Phoh family ABU16_3474 ENOG4105EI1 sporulation protein yqfd ABU16_3475 ENOG41068P3 sporulation protein YqfC ABU16_3477 ENOG4105DI5 UPF0365 protein ABU16_3478 ENOG4105F7J membrane-bound serine protease ABU16_3479 ENOG4105KTH gatB Yqey ABU16_3482 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) ABU16_3483 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) ABU16_3484 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) ABU16_3486 ENOG4105CFG Acts as a chaperone (By similarity) ABU16_3487 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ ABU16_3488 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) ABU16_3489 ENOG4105CSA Coproporphyrinogen iii oxidase ABU16_3490 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) ABU16_3492 ENOG4108ZRV stage ii sporulation protein p ABU16_3493 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) ABU16_3494 ENOG41082YS Binds directly to 16S ribosomal RNA ABU16_3495 ENOG4105TQK DNA polymerase iii, delta' subunit ABU16_3498 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 ABU16_3499 ENOG4108UK2 deaminase ABU16_3500 ENOG4105KQC Competence protein ABU16_3502 ENOG4108D32 Methyltransferase ABU16_3504 ENOG4108WF2 Metal Dependent Phosphohydrolase ABU16_3505 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) ABU16_3506 ENOG410812S Rna-binding protein ABU16_3507 ENOG4105E2X shikimate dehydrogenase ABU16_3508 ENOG4105CQW ribosome biogenesis GTPase YqeH ABU16_3509 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase ABU16_3512 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase ABU16_3513 ENOG41080BT SNARE associated Golgi ABU16_3516 ENOG4105WFK nuclease ABU16_3518 ENOG4107Y5K Resolvase ABU16_3519 ENOG4108UXE Protein tyrosine phosphatase ABU16_3520 ENOG4105D6J arsenicaL-resistance protein ABU16_3521 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase ABU16_3522 ENOG41085FC arsR family transcriptional regulator ABU16_3529 ENOG41064HX Suppressor of fused protein (SUFU) ABU16_3531 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase ABU16_3537 ENOG410906S phage-like element pbsx protein xkdt ABU16_3538 ENOG41066EA baseplate J family protein ABU16_3539 ENOG4105MFU Protein of unknown function (DUF2634) ABU16_3541 ENOG4105X7F ABU16_3542 ENOG4108WZM domain protein ABU16_3543 ENOG4108FKH Transglycosylase SLT domain ABU16_3545 ENOG4105MTC XkdN-like protein ABU16_3547 ENOG4105FR7 XkdM protein, phage-like element PBSX ABU16_3548 ENOG4105PQS phage protein ABU16_3551 ENOG41060SN ABU16_3558 ENOG4106CGH Phage Mu protein F like protein ABU16_3559 ENOG4108MDF Phage Portal Protein ABU16_3560 ENOG4105IG6 Phage terminase, large subunit ABU16_3564 ENOG4106129 ABU16_3566 ENOG4105QBX endodeoxyribonuclease RusA ABU16_3570 ENOG4108PNI recT protein ABU16_3571 ENOG4108NF7 phage-type endonuclease ABU16_3576 ENOG4106A7E Transcriptional regulator ABU16_3577 ENOG41067QW Transcriptional regulator ABU16_3579 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) ABU16_3581 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ABU16_3584 ENOG4108SWU Histidine kinase ABU16_3585 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ABU16_3586 ENOG4105DHF Membrane ABU16_3588 ENOG4108UYN gCN5-related N-acetyltransferase ABU16_3589 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein ABU16_3590 ENOG41068VA ABU16_3591 ENOG41087NI Sulfite exporter TauE/SafE ABU16_3592 ENOG4105VFE sira family ABU16_3593 ENOG4107TPS domain protein ABU16_3594 ENOG4105VFE sira family ABU16_3595 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase ABU16_3596 ENOG4105XTG Pfam:DUF156 ABU16_3598 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein ABU16_3599 ENOG41090E6 transcriptional regulator MERR family ABU16_3602 ENOG4105C37 (CBS) domain ABU16_3605 ENOG410825D TRANSCRIPTIONal REGULATOR, LysR family ABU16_3606 ENOG4105H3G oxidoreductase ABU16_3607 ENOG4105PGM cation diffusion facilitator family transporter ABU16_3608 ENOG41090U3 tautomerase ABU16_3611 ENOG4105KMT branched-chain amino acid ABU16_3612 ENOG4108UMN azlc family ABU16_3613 ENOG4108ZRZ Transcriptional regulator (AsnC family) ABU16_3614 ENOG41067XF inhibitor ABU16_3620 ENOG41075D4 Aminoglycoside 6-adenylyltransferase ABU16_3621 ENOG4105EA8 2-Nitropropane dioxygenase ABU16_3622 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) ABU16_3625 ENOG4108MEK Metal-binding protein YodA ABU16_3626 ENOG410904A RNA polymerase ABU16_3627 ENOG4105CPC Aldo Keto reductase ABU16_3629 ENOG4108KAM Transcriptional regulator ABU16_3631 ENOG4105C7F AcnD-accessory protein PrpF ABU16_3632 ENOG41083Q9 chitosanase ABU16_3633 ENOG4105X5K response regulator receiver protein ABU16_3634 ENOG4108VQT Alpha beta hydrolase fold protein ABU16_3635 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein ABU16_3636 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein ABU16_3637 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase ABU16_3639 ENOG4105PGS Spore coat protein ABU16_3640 ENOG4105E2A Dehydrogenase ABU16_3643 ENOG4105VUF Transcriptional regulator ABU16_3645 ENOG4105DQ4 alcohol dehydrogenase ABU16_3646 ENOG4108Z0Z intracellular protease Pfpi family ABU16_3647 ENOG4108HKT sucrose-6-phosphate hydrolase ABU16_3648 ENOG4105F3R pts system mannose fructose sorbose family iid ABU16_3649 ENOG4105ETZ PTS System ABU16_3650 ENOG4108IQ3 PTS system ABU16_3651 ENOG4105YHU PTS system ABU16_3652 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ABU16_3653 ENOG4105C85 amino acid ABU16_3654 ENOG4105N14 lysine exporter protein LysE YggA ABU16_3655 ENOG4108NGU Transcriptional regulator ABU16_3656 ENOG4105JVQ RNA Polymerase ABU16_3657 ENOG4108P49 AntiSigma factor ABU16_3658 ENOG4105EXC Acyl-transferase ABU16_3659 ENOG4105WDR ABU16_3660 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) ABU16_3661 ENOG41082JN Transcriptional regulator ABU16_3666 ENOG4105TMB Formate nitrite transporter ABU16_3667 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) ABU16_3668 ENOG4108JB9 formate dehydrogenase ABU16_3671 ENOG4105C28 cystathionine ABU16_3674 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) ABU16_3677 ENOG4107XRG penicillin-binding protein ABU16_3678 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) ABU16_3683 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase ABU16_3687 ENOG41068G1 ABU16_3689 ENOG4108S4A n-acetylmuramoyl-l-alanine amidase ABU16_3735 ENOG4108IMY Transcriptional regulator ABU16_3737 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ABU16_3738 ENOG4105DBI uridine monophosphokinase ABU16_3739 ENOG4105CFP Peptidase U32 ABU16_3740 ENOG4105XYU peptidase (U32 family) ABU16_3741 ENOG4108VQJ O-methyltransferase ABU16_3742 ENOG4105HHA aminodeoxychorismate lyase ABU16_3743 ENOG4105VPH UPF0473 protein ABU16_3744 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) ABU16_3745 ENOG4105VBH UPF0297 protein ABU16_3746 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) ABU16_3747 ENOG4105C02 permease ABU16_3748 ENOG4105CDA abc transporter atp-binding protein ABU16_3749 ENOG4105CT1 (ABC) transporter ABU16_3750 ENOG4105EAD ABC transporter ABU16_3751 ENOG4105DRP amino acid AbC transporter ABU16_3753 ENOG41060CR ABU16_3755 ENOG4105C7H Helicase, RecD TraA family ABU16_3757 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) ABU16_3758 ENOG4105C3J Cysteine desulfurase ABU16_3760 ENOG4105D1H recombination factor protein RarA ABU16_3761 ENOG4105CUZ uba thif-type nad fad binding protein ABU16_3763 ENOG4105C9M aspartyl-trna synthetase ABU16_3764 ENOG4105CUT histidyl-tRNA synthetase ABU16_3766 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase ABU16_3768 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) ABU16_3769 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) ABU16_3770 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) ABU16_3771 ENOG41067VP Protein of unknown function (DUF1049) ABU16_3772 ENOG4105NCW Trka-c domain protein ABU16_3773 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ABU16_3775 ENOG4105CKP Polysaccharide Biosynthesis Protein ABU16_3776 ENOG4108QG2 Membrane ABU16_3778 ENOG4105NAP ABU16_3779 ENOG4105VIE preprotein translocase, subunit YajC ABU16_3780 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) ABU16_3781 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) ABU16_3782 ENOG41061AI Protein of unknown function (DUF2905) ABU16_3783 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) ABU16_3784 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) ABU16_3786 ENOG4105IE8 Alpha-ketoglutarate permease ABU16_3787 ENOG4105CK5 oxidoreductase ABU16_3792 ENOG4105BZG amino acid carrier protein ABU16_3793 ENOG4105CDY transcriptional regulatory protein ABU16_3795 ENOG4106678 morphogenetic protein associated with SpoVID ABU16_3796 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) ABU16_3797 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase ABU16_3798 ENOG4108IYU L-aspartate oxidase ABU16_3801 ENOG4105CQC Prephenate dehydratase ABU16_3802 ENOG41090I5 UPF0735 ACT domain-containing protein ABU16_3803 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control ABU16_3806 ENOG4105K46 50S ribosomal protein l27 ABU16_3807 ENOG4105X36 (ribosomal) protein ABU16_3808 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) ABU16_3811 ENOG4107QMS site-determining protein ABU16_3812 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) ABU16_3813 ENOG4105YHC Rod shape-determining protein MreD ABU16_3814 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) ABU16_3815 ENOG4105DFF Rod shape-determining protein mreb ABU16_3816 ENOG4105W5Q DNA repair protein (RadC ABU16_3817 ENOG4108Z03 MAF-like protein ABU16_3819 ENOG4106A3R peptidase ABU16_3821 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase ABU16_3822 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) ABU16_3824 ENOG4106AR7 Spore coat protein ABU16_3825 ENOG41068KH stage VI sporulation protein D ABU16_3826 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase ABU16_3827 ENOG4105D52 delta-aminolevulinic acid dehydratase ABU16_3829 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) ABU16_3831 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) ABU16_3833 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) ABU16_3834 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) ABU16_3835 ENOG4108IUQ atp-dependent protease ABU16_3836 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) ABU16_3837 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation ABU16_3840 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) ABU16_3841 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) ABU16_3842 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) ABU16_3843 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) ABU16_3844 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase ABU16_3845 ENOG4108ZP8 Acetolactate synthase small subunit ABU16_3846 ENOG4105C7K acetolactate synthase ABU16_3848 ENOG4105I4A GCN5-related N-acetyltransferase ABU16_3850 ENOG4107KM7 Heat induced stress protein YflT ABU16_3851 ENOG4105M59 Phosphodiesterase, mj0936 family ABU16_3852 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) ABU16_3853 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) ABU16_3854 ENOG4108XJQ germination protein ABU16_3855 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) ABU16_3856 ENOG41067TZ transcriptional regulator, MarR family ABU16_3858 ENOG4105PFC Transcriptional regulator ABU16_3860 ENOG4105E33 succinate dehydrogenase ABU16_3862 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit ABU16_3864 ENOG4105CFH Aspartokinase ABU16_3866 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) ABU16_3867 ENOG4105K63 Thioredoxin ABU16_3870 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) ABU16_3871 ENOG4105C10 Electron transfer flavoprotein ABU16_3872 ENOG4105BZJ Electron transfer flavoprotein ABU16_3873 ENOG41060WC Enoyl-CoA hydratase ABU16_3874 ENOG4107Z3H Transcriptional regulator, TetR family ABU16_3875 ENOG4105CEY Amp-dependent synthetase and ligase ABU16_3877 ENOG4105C98 muts2 protein ABU16_3878 ENOG4105DCG PHP domain protein ABU16_3881 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) ABU16_3882 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) ABU16_3883 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) ABU16_3885 ENOG4108RWN rrna methyltransferase ABU16_3886 ENOG41067MF small acid-soluble spore protein ABU16_3888 ENOG4105CQB FAD linked oxidase domain protein ABU16_3889 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) ABU16_3892 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) ABU16_3893 ENOG4105DRS transport system, permease ABU16_3896 ENOG4108MDK Dehydrogenase ABU16_3898 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase ABU16_3899 ENOG4105EF1 ribulokinase ABU16_3901 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase ABU16_3902 ENOG4105CN9 Peptidase m42 family protein ABU16_3904 ENOG410696E Membrane ABU16_3905 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) ABU16_3906 ENOG4105VJV 50s ribosomal protein L35 ABU16_3907 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) ABU16_3910 ENOG41067MG lrgb family ABU16_3912 ENOG4105DY9 regulatoR ABU16_3913 ENOG4108HRK Histidine kinase ABU16_3914 ENOG4105U0R haloacid dehalogenase-like hydrolase ABU16_3915 ENOG4105C22 threonyL-tRNA synthetase ABU16_3917 ENOG4108TDW sporulation protein YtxC ABU16_3921 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) ABU16_3922 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) ABU16_3923 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ABU16_3924 ENOG4105KVH Transcriptional regulator ABU16_3925 ENOG4105F27 Major Facilitator ABU16_3926 ENOG4105CV8 reductase ABU16_3927 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) ABU16_3929 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) ABU16_3930 ENOG4105C2M dna polymerase I ABU16_3931 ENOG4105BZU Histidine kinase ABU16_3932 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ABU16_3934 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) ABU16_3935 ENOG4108HMX isocitrate dehydrogenase (NADP) ABU16_3936 ENOG4105BZN citrate synthase ABU16_3938 ENOG4108REF Sporulation integral membrane protein ytvi ABU16_3939 ENOG4105FS0 cytoplasmic membrane protein ABU16_3940 ENOG4105CA9 Pyruvate kinase ABU16_3941 ENOG4105CTQ phosphohexokinase ABU16_3943 ENOG4108IEY Carboxyl transferase domain ABU16_3944 ENOG4105C6K Malic enzyme ABU16_3945 ENOG4105C0B DNA polymerase III (alpha subunit) ABU16_3946 ENOG4105VV2 ABU16_3948 ENOG4106EVM ABU16_3949 ENOG4105SFS phosphoesterase RecJ domain protein ABU16_3953 ENOG410635A Membrane ABU16_3954 ENOG4105CH2 amidohydrolase ABU16_3958 ENOG4105DEN Luciferase family ABU16_3959 ENOG4105CDA abc transporter atp-binding protein ABU16_3964 ENOG4108XSB acetyltransferase, (GNAT) family ABU16_3965 ENOG4108KSA LysR family transcriptional regulator ABU16_3966 ENOG4105E8R UPF0173 metal-dependent hydrolase ABU16_3969 ENOG4105CH7 arginosuccinase ABU16_3970 ENOG4105CDH Citrulline--aspartate ligase ABU16_3971 ENOG4105EPU Molybdenum cofactor synthesis domain protein ABU16_3972 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) ABU16_3975 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) ABU16_3976 ENOG4105KBJ sporulation protein ytfj ABU16_3978 ENOG4105VK3 rdd domain containing protein ABU16_3979 ENOG4105D07 Signal peptide peptidase, SppA ABU16_3981 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) ABU16_3982 ENOG4105EFZ amidohydrolase ABU16_3983 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) ABU16_3990 ENOG4105U5Y Transcriptional regulator ABU16_3992 ENOG4105BZU Histidine kinase ABU16_3994 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) ABU16_3996 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) ABU16_3998 ENOG4105F1V Acetoin utilization protein ABU16_3999 ENOG4105W87 Cbs domain ABU16_4000 ENOG4105DGU Histone deacetylase ABU16_4001 ENOG4105ER2 Ompa motb domain protein ABU16_4002 ENOG4107R0U MotA TolQ exbB proton channel ABU16_4003 ENOG4105ETE Transcriptional regulator (LacI family ABU16_4004 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase ABU16_4008 ENOG4105DFU Cell wall formation (By similarity) ABU16_4010 ENOG4108VDD TRNA binding domain protein ABU16_4014 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ ABU16_4017 ENOG4105C6K Malic enzyme ABU16_4018 ENOG4105C8F Beta-lactamase domain protein ABU16_4019 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) ABU16_4021 ENOG4108V15 phosphotransferase enzyme family ABU16_4022 ENOG4108IUM Glycogen debranching enzyme ABU16_4025 ENOG4107F58 2'-5' rna ligase ABU16_4026 ENOG4105C6T cysteine synthase ABU16_4027 ENOG4107QSE Dipeptidase ABU16_4028 ENOG4105C7N Xanthine uracil vitamin C permease ABU16_4031 ENOG4105YW5 deoR family transcriptional regulator ABU16_4034 ENOG4105CBX hi0933 family ABU16_4035 ENOG4105C94 Transporter ABU16_4037 ENOG4105MU9 integral membrane protein ABU16_4038 ENOG4105DDC Oxidoreductase domain protein ABU16_4040 ENOG4105F5H Glycosyl Hydrolase Family 88 ABU16_4042 ENOG41075H3 AraC family transcriptional regulator ABU16_4044 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component ABU16_4046 ENOG4106A3M Cytochrome p-450 ABU16_4047 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) ABU16_4049 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ABU16_4050 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ABU16_4052 ENOG4105NTD Inherit from COG: Hydrolase ABU16_4055 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component ABU16_4056 ENOG4105I1K ABC transporter ABU16_4058 ENOG41085GJ domain protein ABU16_4059 ENOG4105C8T Leucyl-tRNA synthetase ABU16_4062 ENOG4105BZU Histidine kinase ABU16_4063 ENOG410605W Major Facilitator ABU16_4064 ENOG4106UBQ ABU16_4066 ENOG4105C19 ABC transporter ABU16_4067 ENOG4105EWM Histidine kinase ABU16_4069 ENOG4107R34 abc transporter permease protein ABU16_4070 ENOG4105C19 ABC transporter ABU16_4073 ENOG4105DVE abc transporter atp-binding protein ABU16_4074 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family ABU16_4077 ENOG4105N5T Radical SAM Protein ABU16_4080 ENOG4105E8V Alpha Beta Hydrolase Fold protein ABU16_4081 ENOG4108Z0R Transferase ABU16_4082 ENOG4105C85 amino acid ABU16_4083 ENOG4105CAQ asparagine synthetase ABU16_4084 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP ABU16_4085 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase ABU16_4088 ENOG4105D2X ABC transporter substrate-binding protein ABU16_4090 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component ABU16_4093 ENOG4108RMU ferritin dps family protein ABU16_4096 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) ABU16_4097 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) ABU16_4098 ENOG4108V2W Carbonate dehydratase ABU16_4103 ENOG4105CC5 ABC transporter ABU16_4104 ENOG4105CC5 ABC transporter ABU16_4105 ENOG4105DIK (ABC) transporter ABU16_4106 ENOG4105DSE periplasmic solute binding protein ABU16_4107 ENOG4105DTQ mandelate racemase muconate lactonizing ABU16_4108 ENOG4105CEY Amp-dependent synthetase and ligase ABU16_4109 ENOG4108IPT Naphthoate synthase ABU16_4110 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) ABU16_4111 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) ABU16_4112 ENOG4105E4F Isochorismate synthase ABU16_4117 ENOG4108IAJ Nad-dependent epimerase dehydratase ABU16_4118 ENOG4107SBE Glycosyl transferase (Group 1 ABU16_4121 ENOG4107SBE Glycosyl transferase (Group 1 ABU16_4122 ENOG4108KS4 Spore coat protein ABU16_4125 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) ABU16_4127 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) ABU16_4129 ENOG4105N67 Proton-coupled thiamine transporter YuaJ ABU16_4130 ENOG4105VRR gCN5-related N-acetyltransferase ABU16_4131 ENOG4105DZ6 Band 7 protein ABU16_4133 ENOG4106DF1 ABU16_4134 ENOG4108VNY MOSC domain protein ABU16_4135 ENOG4108JB8 alcohol dehydrogenase ABU16_4136 ENOG4105C26 Dehydrogenase ABU16_4137 ENOG4105TRT Transcriptional regulator ABU16_4140 ENOG4105CZN Potassium uptake protein ABU16_4141 ENOG4107I77 yiaA/B two helix domain ABU16_4142 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj ABU16_4146 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) ABU16_4148 ENOG4105EE0 oxidoreductase ABU16_4149 ENOG4105DKG l-rhamnose isomerase ABU16_4150 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) ABU16_4151 ENOG4105DET Rhamnulokinase ABU16_4152 ENOG4105E98 transcriptional regulator DeoR family ABU16_4155 ENOG4105C8Q Methyl-accepting chemotaxis ABU16_4156 ENOG4105C8Q Methyl-accepting chemotaxis ABU16_4157 ENOG4105C8Q Methyl-accepting chemotaxis ABU16_4158 ENOG4105C8Q Methyl-accepting chemotaxis ABU16_4162 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme ABU16_4164 ENOG4105C37 (CBS) domain ABU16_4167 ENOG4107PBV potassium channel ABU16_4168 ENOG4107PBV potassium channel ABU16_4171 ENOG4107QYV phosphohexose isomerase ABU16_4173 ENOG4107QW4 alcohol dehydrogenase ABU16_4174 ENOG4105WG9 Conserved Protein ABU16_4176 ENOG4105CHM Aminotransferase ABU16_4177 ENOG4108ZB6 transcriptional regulator AsnC family ABU16_4178 ENOG4108MUZ hydrolase ABU16_4180 ENOG4105C87 Aminotransferase class I and II ABU16_4181 ENOG4108HGU Histidine kinase ABU16_4182 ENOG4105Y38 Kinase-associated protein B ABU16_4186 ENOG4105BZ4 penicillin-binding protein ABU16_4187 ENOG4105KIR Thiol-disulfide oxidoreductase dcc ABU16_4190 ENOG4108MRH transcriptional regulatory protein ABU16_4191 ENOG4105DIH basic membrane ABU16_4192 ENOG4108JQ9 ABC transporter ABU16_4193 ENOG4105UIB (ABC) transporter ABU16_4197 ENOG4105D65 subunit l ABU16_4198 ENOG4105HC0 Na H antiporter ABU16_4199 ENOG4108ZE9 Monovalent cation H antiporter subunit C ABU16_4200 ENOG4108JPZ Monovalent cation H antiporter subunit D ABU16_4201 ENOG4105SC1 monovalent cation H antiporter subunit E ABU16_4203 ENOG4105KJM monovalent cation h antiporter subunit g ABU16_4204 ENOG4105KA0 thioesterase Superfamily protein ABU16_4206 ENOG4105BZU Histidine kinase ABU16_4213 ENOG4105D58 Diguanylate phosphodiesterase ABU16_4214 ENOG4105DAP Nicotinate phosphoribosyltransferase ABU16_4219 ENOG4105C02 permease ABU16_4223 ENOG410904N short-chain dehydrogenase reductase