locus-tag	class	description
N6G78_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N6G78_00010	COG0592	DNA-directed DNA polymerase activity
N6G78_00015	COG2501	S4 domain
N6G78_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N6G78_00030	COG0187	DNA topoisomerase II activity
N6G78_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N6G78_00070	COG0516	GMP reductase activity
N6G78_00070	COG0517	IMP dehydrogenase activity
N6G78_00075	COG1686	Belongs to the peptidase S11 family
N6G78_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
N6G78_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
N6G78_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N6G78_00100	COG1428	Deoxynucleoside kinase
N6G78_00105	COG1428	Deoxynucleoside kinase
N6G78_00110	COG1388	LysM domain
N6G78_00110	COG3858	chitin binding
N6G78_00115	COG1335	isochorismatase
N6G78_00120	COG0590	tRNA wobble adenosine to inosine editing
N6G78_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N6G78_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N6G78_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N6G78_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
N6G78_00190	COG3853	Toxic anion resistance protein (TelA)
N6G78_00195	COG1982	Orn Lys Arg decarboxylase major
N6G78_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N6G78_00205	COG3870	Protein conserved in bacteria
N6G78_00210	COG1728	Protein conserved in bacteria
N6G78_00215	COG0470	DNA polymerase III
N6G78_00220	COG1774	PSP1 C-terminal conserved region
N6G78_00225	COG4467	Involved in initiation control of chromosome replication
N6G78_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N6G78_00235	COG2827	Endonuclease containing a URI domain
N6G78_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N6G78_00245	COG2002	toxin-antitoxin pair type II binding
N6G78_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N6G78_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N6G78_00255	COG0084	hydrolase, TatD family'
N6G78_00260	COG3583	domain protein
N6G78_00260	COG3584	3D domain protein
N6G78_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N6G78_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N6G78_00280	COG4466	Protein conserved in bacteria
N6G78_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N6G78_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N6G78_00300	COG0251	oxidation-reduction process
N6G78_00305	COG2088	sporulation resulting in formation of a cellular spore
N6G78_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N6G78_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N6G78_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N6G78_00325	COG0193	aminoacyl-tRNA hydrolase activity
N6G78_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N6G78_00340	COG2002	toxin-antitoxin pair type II binding
N6G78_00345	COG2244	polysaccharide biosynthetic process
N6G78_00350	COG3956	TIGRFAM MazG family protein
N6G78_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N6G78_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N6G78_00375	COG1098	S1 RNA binding domain
N6G78_00390	COG2208	phosphoserine phosphatase activity
N6G78_00395	COG2304	oxidoreductase activity
N6G78_00400	COG0515	serine threonine protein kinase
N6G78_00405	COG0037	tRNA processing
N6G78_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
N6G78_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N6G78_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
N6G78_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N6G78_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N6G78_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N6G78_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N6G78_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
N6G78_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N6G78_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N6G78_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N6G78_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N6G78_00470	COG1396	sequence-specific DNA binding
N6G78_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N6G78_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N6G78_00560	COG4463	regulation of RNA biosynthetic process
N6G78_00565	COG3880	PFAM UvrB UvrC protein
N6G78_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
N6G78_00575	COG0542	response to heat
N6G78_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N6G78_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
N6G78_00590	COG4956	integral membrane protein (PIN domain superfamily)
N6G78_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N6G78_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N6G78_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N6G78_00610	COG1045	serine acetyltransferase
N6G78_00615	COG0215	cysteine-tRNA ligase activity
N6G78_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
N6G78_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N6G78_00630	COG3688	RNA-binding protein containing a PIN domain
N6G78_00635	COG1595	DNA-templated transcription, initiation
N6G78_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N6G78_00650	COG0250	Participates in transcription elongation, termination and antitermination
N6G78_00660	COG0081	regulation of translation
N6G78_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N6G78_00675	COG2813	Specifically methylates the guanine in position
N6G78_00680	COG0085	RNA polymerase activity
N6G78_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N6G78_00690	COG1358	cellular component organization or biogenesis
N6G78_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N6G78_00700	COG0049	tRNA binding
N6G78_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N6G78_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N6G78_00715	COG0596	Alpha beta hydrolase
N6G78_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N6G78_00730	COG0088	Forms part of the polypeptide exit tunnel
N6G78_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N6G78_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N6G78_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N6G78_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N6G78_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N6G78_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N6G78_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N6G78_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N6G78_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N6G78_00820	COG0200	Binds to the 23S rRNA
N6G78_00825	COG0201	protein transport
N6G78_00830	COG0563	adenylate kinase activity
N6G78_00835	COG0024	Methionine aminopeptidase
N6G78_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
N6G78_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N6G78_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N6G78_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N6G78_00865	COG0202	RNA polymerase activity
N6G78_00870	COG0203	ribosomal protein L17
N6G78_00875	COG1122	ATPase activity
N6G78_00880	COG1122	ATPase activity
N6G78_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N6G78_00890	COG0101	tRNA pseudouridine synthase activity
N6G78_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N6G78_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N6G78_00905	COG2226	methyltransferase
N6G78_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
N6G78_00920	COG0489	protein tyrosine kinase activity
N6G78_00930	COG2194	sulfuric ester hydrolase activity
N6G78_00935	COG0726	polysaccharide deacetylase
N6G78_01015	COG0659	secondary active sulfate transmembrane transporter activity
N6G78_01020	COG0385	Bile acid
N6G78_01025	COG2819	hydrolase of the alpha beta superfamily
N6G78_01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N6G78_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N6G78_01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N6G78_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N6G78_01045	COG2207	Transcriptional regulator
N6G78_01050	COG3876	Protein conserved in bacteria
N6G78_01055	COG1472	Belongs to the glycosyl hydrolase 3 family
N6G78_01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N6G78_01065	COG1263	PTS System
N6G78_01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N6G78_01070	COG1737	Transcriptional regulator
N6G78_01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N6G78_01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N6G78_01085	COG1683	Conserved Protein
N6G78_01115	COG1595	DNA-templated transcription, initiation
N6G78_01120	COG5662	AntiSigma factor
N6G78_01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N6G78_01130	COG4856	YbbR-like protein
N6G78_01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N6G78_01140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N6G78_01150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N6G78_01155	COG3002	Belongs to the UPF0753 family
N6G78_01160	COG0288	reversible hydration of carbon dioxide
N6G78_01170	COG5609	conserved protein (DUF2294)
N6G78_01175	COG0640	Transcriptional regulator
N6G78_01180	COG2814	Major facilitator Superfamily
N6G78_01195	COG0596	Alpha beta hydrolase
N6G78_01200	COG0745	RESPONSE REGULATOR receiver
N6G78_01205	COG0642	Histidine kinase
N6G78_01215	COG0515	serine threonine protein kinase
N6G78_01230	COG1113	amino acid transport
N6G78_01245	COG2602	Beta-lactamase
N6G78_01250	COG2124	cytochrome p450
N6G78_01260	COG0531	amino acid
N6G78_01265	COG0584	glycerophosphoryl diester phosphodiesterase
N6G78_01270	COG2271	Major facilitator Superfamily
N6G78_01280	COG0456	acetyltransferase
N6G78_01280	COG1846	Transcriptional regulator
N6G78_01285	COG2271	Major facilitator Superfamily
N6G78_01295	COG0697	spore germination
N6G78_01300	COG1917	Cupin 2, conserved barrel domain protein
N6G78_01300	COG2207	Transcriptional regulator
N6G78_01305	COG1397	ADP-ribosylglycohydrolase
N6G78_01310	COG5444	nuclease activity
N6G78_01315	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
N6G78_01320	COG3591	Belongs to the peptidase S1B family
N6G78_01330	COG0596	Alpha beta hydrolase
N6G78_01335	COG1183	phosphatidylcholine synthase activity
N6G78_01340	COG0586	Pfam SNARE associated Golgi protein
N6G78_01345	COG0688	phosphatidylethanolamine metabolic process
N6G78_01355	COG2312	Erythromycin esterase
N6G78_01360	COG1054	Belongs to the UPF0176 family
N6G78_01365	COG1301	dicarboxylic acid transport
N6G78_01370	COG2190	(PTS) system
N6G78_01370	COG1263	PTS System
N6G78_01370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N6G78_01375	COG0363	glucosamine-6-phosphate deaminase activity
N6G78_01380	COG2188	Transcriptional regulator
N6G78_01390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N6G78_01395	COG0833	amino acid
N6G78_01400	COG2040	homocysteine
N6G78_01405	COG1115	amino acid carrier protein
N6G78_01410	COG2066	Belongs to the glutaminase family
N6G78_01415	COG4191	Histidine kinase
N6G78_01420	COG0784	Response regulator, receiver
N6G78_01425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N6G78_01430	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_01435	COG2271	Major facilitator Superfamily
N6G78_01440	COG4948	Mandelate Racemase Muconate Lactonizing
N6G78_01445	COG2186	Transcriptional regulator
N6G78_01450	COG2721	sulfolactate sulfo-lyase activity
N6G78_01455	COG3173	Aminoglycoside phosphotransferase
N6G78_01465	COG0697	spore germination
N6G78_01470	COG0745	RESPONSE REGULATOR receiver
N6G78_01475	COG2205	protein histidine kinase activity
N6G78_01480	COG1131	(ABC) transporter
N6G78_01500	COG3773	Cell wall hydrolase
N6G78_01505	COG2304	oxidoreductase activity
N6G78_01515	COG3540	Alkaline phosphatase
N6G78_01520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N6G78_01525	COG0805	protein transport
N6G78_01530	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
N6G78_01535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N6G78_01540	COG0477	Major facilitator Superfamily
N6G78_01545	COG1309	transcriptional regulator
N6G78_01550	COG0252	asparaginase activity
N6G78_01555	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N6G78_01560	COG1714	RDD family
N6G78_01565	COG3012	SEC-C Motif Domain Protein
N6G78_01565	COG1405	negative regulation of cell septum assembly
N6G78_01570	COG3290	protein histidine kinase activity
N6G78_01575	COG3279	Response regulator of the LytR AlgR family
N6G78_01580	COG4555	ABC transporter
N6G78_01585	COG1668	transmembrane transport
N6G78_01590	COG0667	Aldo Keto reductase
N6G78_01605	COG1595	DNA-templated transcription, initiation
N6G78_01610	COG1595	DNA-templated transcription, initiation
N6G78_01615	COG1876	peptidase activity
N6G78_01620	COG0457	Tetratricopeptide repeat
N6G78_01625	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_01630	COG0366	Alpha amylase catalytic
N6G78_01635	COG0803	Belongs to the bacterial solute-binding protein 9 family
N6G78_01640	COG1121	(ABC) transporter
N6G78_01645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N6G78_01650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N6G78_01655	COG2310	stress, protein
N6G78_01660	COG2310	stress, protein
N6G78_01665	COG2310	stress, protein
N6G78_01670	COG0861	Integral membrane protein TerC family
N6G78_01680	COG3853	Toxic anion resistance protein (TelA)
N6G78_01685	COG0477	Major facilitator Superfamily
N6G78_01690	COG2814	Major facilitator Superfamily
N6G78_01695	COG0640	Transcriptional regulator
N6G78_01700	COG4175	Glycine betaine
N6G78_01700	COG0517	IMP dehydrogenase activity
N6G78_01705	COG4176	ABC-type proline glycine betaine transport system permease component
N6G78_01710	COG2113	Glycine betaine
N6G78_01715	COG1473	amidohydrolase
N6G78_01720	COG1288	antiporter activity
N6G78_01730	COG0366	Alpha amylase catalytic
N6G78_01735	COG0039	L-malate dehydrogenase activity
N6G78_01740	COG1620	l-lactate permease
N6G78_01745	COG2814	Major facilitator Superfamily
N6G78_01750	COG1846	Transcriptional regulator
N6G78_01755	COG1280	lysine exporter protein (LysE YggA)
N6G78_01760	COG3403	YqcI/YcgG family
N6G78_01765	COG1113	amino acid transport
N6G78_01770	COG3665	Urea carboxylase-associated protein
N6G78_01775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N6G78_01780	COG1660	Displays ATPase and GTPase activities
N6G78_01785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N6G78_01790	COG2226	methyltransferase
N6G78_01795	COG0583	DNA-binding transcription factor activity
N6G78_01800	COG3458	cephalosporin-C deacetylase activity
N6G78_01805	COG3541	Predicted nucleotidyltransferase
N6G78_01810	COG0506	proline dehydrogenase activity
N6G78_01815	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_01820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N6G78_01825	COG2508	Transcriptional regulator
N6G78_01830	COG3689	TIGRFAM TIGR03943 family protein
N6G78_01835	COG0701	Predicted permease
N6G78_01840	COG2267	carboxylic ester hydrolase activity
N6G78_01845	COG0492	ferredoxin-NADP+ reductase activity
N6G78_01850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N6G78_01850	COG1587	Uroporphyrinogen-III synthase
N6G78_01855	COG2146	nitrite reductase [NAD(P)H] activity
N6G78_01860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N6G78_01865	COG0243	molybdopterin cofactor binding
N6G78_01870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N6G78_01875	COG2223	nitrite transmembrane transporter activity
N6G78_01880	COG1469	GTP cyclohydrolase I activity
N6G78_01885	COG1376	ErfK ybiS ycfS ynhG family protein
N6G78_01895	COG0523	cobalamin synthesis protein
N6G78_01900	COG0765	amino acid transport
N6G78_01905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N6G78_01915	COG1714	RDD family
N6G78_01925	COG2723	6-phospho-beta-galactosidase activity
N6G78_01935	COG3209	COG3209 Rhs family protein
N6G78_01940	COG0840	transmembrane signaling receptor activity
N6G78_01940	COG3290	protein histidine kinase activity
N6G78_01945	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N6G78_01950	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
N6G78_01955	COG1733	regulation of RNA biosynthetic process
N6G78_01960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_01990	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N6G78_01995	COG2814	Major facilitator Superfamily
N6G78_02005	COG0697	spore germination
N6G78_02010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N6G78_02020	COG2364	Membrane
N6G78_02025	COG1126	abc transporter atp-binding protein
N6G78_02030	COG0765	amino acid transport
N6G78_02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N6G78_02040	COG0583	DNA-binding transcription factor activity
N6G78_02045	COG0163	prenyltransferase activity
N6G78_02050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N6G78_02065	COG0596	Alpha beta hydrolase
N6G78_02070	COG3104	oligopeptide transport
N6G78_02075	COG5434	Belongs to the glycosyl hydrolase 28 family
N6G78_02085	COG0697	spore germination
N6G78_02095	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N6G78_02100	COG1136	(ABC) transporter
N6G78_02105	COG0577	efflux transmembrane transporter activity
N6G78_02110	COG0745	RESPONSE REGULATOR receiver
N6G78_02115	COG5002	protein histidine kinase activity
N6G78_02115	COG3850	Histidine kinase
N6G78_02120	COG0457	Tetratricopeptide repeat
N6G78_02140	COG0527	aspartate kinase activity
N6G78_02145	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N6G78_02150	COG4605	iron ion homeostasis
N6G78_02155	COG4604	ABC transporter, ATP-binding protein
N6G78_02160	COG4607	ABC-type enterochelin transport system periplasmic component
N6G78_02165	COG2814	Major facilitator Superfamily
N6G78_02170	COG1309	transcriptional regulator
N6G78_02175	COG0778	Nitroreductase
N6G78_02180	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N6G78_02185	COG0640	Transcriptional regulator
N6G78_02190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N6G78_02195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N6G78_02200	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_02205	COG4975	Glucose uptake
N6G78_02210	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_02215	COG4549	nuclear export factor GLE1
N6G78_02220	COG1276	copper resistance
N6G78_02220	COG2372	response to copper ion
N6G78_02225	COG1349	DNA-binding transcription factor activity
N6G78_02235	COG2213	PTS system mannitol-specific
N6G78_02240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N6G78_02245	COG0246	Mannitol dehydrogenase
N6G78_02250	COG0473	3-isopropylmalate dehydrogenase activity
N6G78_02255	COG0681	Belongs to the peptidase S26 family
N6G78_02260	COG0412	Dienelactone hydrolase
N6G78_02265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N6G78_02275	COG0561	phosphatase activity
N6G78_02280	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
N6G78_02285	COG1914	H( )-stimulated, divalent metal cation uptake system
N6G78_02290	COG4336	lyase activity
N6G78_02295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
N6G78_02300	COG1984	allophanate hydrolase subunit 2
N6G78_02305	COG1414	Transcriptional regulator
N6G78_02310	COG2755	lipolytic protein G-D-S-L family
N6G78_02320	COG2329	Antibiotic biosynthesis monooxygenase
N6G78_02325	COG0768	penicillin binding
N6G78_02330	COG4989	oxidoreductase activity
N6G78_02335	COG3711	transcriptional antiterminator
N6G78_02340	COG0318	PFAM AMP-dependent synthetase and ligase
N6G78_02345	COG2226	methyltransferase
N6G78_02350	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_02355	COG1917	Cupin 2, conserved barrel domain protein
N6G78_02360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N6G78_02365	COG3871	stress protein (general stress protein 26)
N6G78_02375	COG2814	Major facilitator Superfamily
N6G78_02380	COG1522	sequence-specific DNA binding
N6G78_02385	COG0551	DNA topoisomerase type I activity
N6G78_02385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N6G78_02390	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
N6G78_02395	COG3706	GGDEF domain
N6G78_02400	COG5298	Protein conserved in bacteria
N6G78_02405	COG1215	transferase activity, transferring glycosyl groups
N6G78_02415	COG0531	amino acid
N6G78_02420	COG0494	nUDIX hydrolase
N6G78_02425	COG0028	Belongs to the TPP enzyme family
N6G78_02440	COG1914	H( )-stimulated, divalent metal cation uptake system
N6G78_02445	COG2261	transglycosylase associated protein
N6G78_02450	COG4876	unkown
N6G78_02455	COG2217	Heavy metal translocating P-type atpase
N6G78_02460	COG3729	General stress protein
N6G78_02465	COG0662	Cupin 2, conserved barrel domain protein
N6G78_02470	COG2329	Antibiotic biosynthesis monooxygenase
N6G78_02475	COG3546	catalase activity
N6G78_02480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N6G78_02485	COG3290	protein histidine kinase activity
N6G78_02490	COG4565	transcriptional regulatory protein
N6G78_02495	COG1301	dicarboxylic acid transport
N6G78_02500	COG0628	permease
N6G78_02510	COG1131	(ABC) transporter
N6G78_02515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N6G78_02525	COG1960	acyl-CoA dehydrogenase activity
N6G78_02540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N6G78_02545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N6G78_02550	COG1181	Belongs to the D-alanine--D-alanine ligase family
N6G78_02555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N6G78_02560	COG0513	Belongs to the DEAD box helicase family
N6G78_02565	COG3402	PFAM membrane-flanked domain
N6G78_02570	COG3428	Bacterial PH domain
N6G78_02575	COG0705	Rhomboid family
N6G78_02580	COG0736	holo-[acyl-carrier-protein] synthase activity
N6G78_02585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N6G78_02590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N6G78_02595	COG0864	Transcriptional regulator
N6G78_02600	COG2337	Toxic component of a toxin-antitoxin (TA) module
N6G78_02605	COG1366	Belongs to the anti-sigma-factor antagonist family
N6G78_02610	COG1366	Belongs to the anti-sigma-factor antagonist family
N6G78_02615	COG2172	sigma factor antagonist activity
N6G78_02620	COG2208	phosphoserine phosphatase activity
N6G78_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
N6G78_02630	COG2172	sigma factor antagonist activity
N6G78_02635	COG1191	sigma factor activity
N6G78_02640	COG2208	phosphoserine phosphatase activity
N6G78_02650	COG1673	EVE domain
N6G78_02655	COG1846	Transcriptional regulator
N6G78_02660	COG2183	response to ionizing radiation
N6G78_02670	COG3091	SprT-like family
N6G78_02720	COG0515	serine threonine protein kinase
N6G78_02750	COG0515	serine threonine protein kinase
N6G78_02755	COG1132	(ABC) transporter
N6G78_02775	COG1476	TRANSCRIPTIONal
N6G78_02785	COG3239	Fatty acid desaturase
N6G78_02790	COG1278	Cold shock
N6G78_02795	COG1329	Transcriptional regulator
N6G78_02800	COG2207	Transcriptional regulator
N6G78_02800	COG1917	Cupin 2, conserved barrel domain protein
N6G78_02805	COG0697	spore germination
N6G78_02810	COG3708	Transcriptional regulator
N6G78_02810	COG2207	Transcriptional regulator
N6G78_02815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N6G78_02820	COG0477	Major facilitator Superfamily
N6G78_02830	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
N6G78_02840	COG0697	spore germination
N6G78_02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N6G78_02850	COG2030	dehydratase
N6G78_02855	COG3545	Serine hydrolase
N6G78_02860	COG1733	regulation of RNA biosynthetic process
N6G78_02865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N6G78_02870	COG1733	regulation of RNA biosynthetic process
N6G78_02875	COG2249	NAD(P)H dehydrogenase (quinone) activity
N6G78_02880	COG2814	Major facilitator Superfamily
N6G78_02885	COG1309	transcriptional regulator
N6G78_02895	COG0640	Transcriptional regulator
N6G78_02900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N6G78_02910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N6G78_02915	COG1316	TRANSCRIPTIONal
N6G78_02930	COG5002	protein histidine kinase activity
N6G78_02935	COG0745	RESPONSE REGULATOR receiver
N6G78_02940	COG0697	spore germination
N6G78_02945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N6G78_02950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N6G78_02955	COG0640	Transcriptional regulator
N6G78_02960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N6G78_02975	COG4585	Histidine kinase
N6G78_02980	COG2197	response regulator
N6G78_02985	COG2409	Drug exporters of the RND superfamily
N6G78_02990	COG0596	Alpha beta hydrolase
N6G78_02995	COG1811	Na channel or pump
N6G78_03000	COG4978	Transcriptional regulator
N6G78_03000	COG0789	Transcriptional regulator
N6G78_03005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N6G78_03010	COG0778	Nitroreductase
N6G78_03015	COG0346	lactoylglutathione lyase activity
N6G78_03020	COG2259	Doxx family
N6G78_03025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N6G78_03045	COG2323	membrane
N6G78_03055	COG0071	Belongs to the small heat shock protein (HSP20) family
N6G78_03070	COG1309	transcriptional regulator
N6G78_03080	COG0456	acetyltransferase
N6G78_03090	COG2814	Major facilitator Superfamily
N6G78_03100	COG0488	(ABC) transporter
N6G78_03105	COG1113	amino acid transport
N6G78_03110	COG2318	DinB family
N6G78_03115	COG1846	Transcriptional regulator
N6G78_03120	COG1033	growth of symbiont in host cell
N6G78_03120	COG2409	Drug exporters of the RND superfamily
N6G78_03125	COG0778	Nitroreductase
N6G78_03130	COG1846	Transcriptional regulator
N6G78_03135	COG2814	Major facilitator Superfamily
N6G78_03140	COG0730	response to heat
N6G78_03145	COG1802	Transcriptional regulator
N6G78_03150	COG3858	chitin binding
N6G78_03150	COG1388	LysM domain
N6G78_03155	COG1819	glycosyl
N6G78_03165	COG1785	Belongs to the alkaline phosphatase family
N6G78_03170	COG5646	InterPro IPR014922
N6G78_03180	COG0454	-acetyltransferase
N6G78_03185	COG1078	dGTPase activity
N6G78_03190	COG1388	LysM domain
N6G78_03195	COG2814	Major facilitator Superfamily
N6G78_03200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N6G78_03205	COG1447	Phosphotransferase system cellobiose-specific component IIA
N6G78_03210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N6G78_03215	COG2723	6-phospho-beta-galactosidase activity
N6G78_03220	COG2188	Transcriptional regulator
N6G78_03225	COG1940	carbohydrate kinase activity
N6G78_03230	COG1482	cell wall glycoprotein biosynthetic process
N6G78_03235	COG4124	Belongs to the glycosyl hydrolase 26 family
N6G78_03280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N6G78_03285	COG0802	atpase or kinase
N6G78_03290	COG1214	PFAM Peptidase M22, glycoprotease
N6G78_03295	COG0456	acetyltransferase
N6G78_03300	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N6G78_03305	COG0488	(ABC) transporter
N6G78_03310	COG0315	cyclic pyranopterin monophosphate synthase activity
N6G78_03315	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
N6G78_03320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N6G78_03325	COG0805	protein transport
N6G78_03335	COG1266	CAAX protease self-immunity
N6G78_03345	COG0459	protein refolding
N6G78_03355	COG1073	alpha beta
N6G78_03360	COG0457	Tetratricopeptide repeat
N6G78_03365	COG1063	alcohol dehydrogenase
N6G78_03370	COG2211	Major facilitator Superfamily
N6G78_03375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N6G78_03380	COG1842	Phage shock protein A
N6G78_03385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N6G78_03390	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
N6G78_03395	COG4260	virion core protein, lumpy skin disease virus
N6G78_03405	COG2814	Major facilitator Superfamily
N6G78_03410	COG1063	alcohol dehydrogenase
N6G78_03415	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N6G78_03420	COG0823	Involved in the tonB-independent uptake of proteins
N6G78_03435	COG2267	carboxylic ester hydrolase activity
N6G78_03445	COG2132	Multicopper oxidase
N6G78_03450	COG1113	amino acid transport
N6G78_03460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N6G78_03465	COG0714	Associated with various cellular activities
N6G78_03470	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
N6G78_03475	COG1305	Transglutaminase-like
N6G78_03485	COG0519	Catalyzes the synthesis of GMP from XMP
N6G78_03485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N6G78_03500	COG2252	PERMEase
N6G78_03505	COG3064	Membrane
N6G78_03515	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
N6G78_03525	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N6G78_03530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N6G78_03535	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N6G78_03540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N6G78_03545	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N6G78_03550	COG0047	phosphoribosylformylglycinamidine synthase activity
N6G78_03555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N6G78_03560	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N6G78_03565	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N6G78_03570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N6G78_03575	COG0138	bifunctional purine biosynthesis protein purh
N6G78_03580	COG0151	Belongs to the GarS family
N6G78_03585	COG1522	sequence-specific DNA binding
N6G78_03590	COG0531	amino acid
N6G78_03600	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N6G78_03605	COG1470	cell adhesion involved in biofilm formation
N6G78_03610	COG4496	protein, YerC YecD
N6G78_03615	COG0069	glutamate synthase activity
N6G78_03620	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
N6G78_03625	COG0210	DNA helicase
N6G78_03630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N6G78_03635	COG4851	CamS sex pheromone cAM373 precursor
N6G78_03640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N6G78_03645	COG1285	pathogenesis
N6G78_03650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N6G78_03655	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N6G78_03660	COG0154	amidase activity
N6G78_03665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N6G78_03675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N6G78_03680	COG1597	lipid kinase activity
N6G78_03685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N6G78_03690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N6G78_03700	COG5293	efflux transmembrane transporter activity
N6G78_03740	COG5444	nuclease activity
N6G78_03750	COG3586	endonuclease activity
N6G78_03760	COG0457	Tetratricopeptide repeat
N6G78_03770	COG0217	transcriptional regulatory protein
N6G78_03780	COG1309	transcriptional regulator
N6G78_03785	COG3631	Ketosteroid isomerase-related protein
N6G78_03805	COG3546	catalase activity
N6G78_03810	COG0454	-acetyltransferase
N6G78_03820	COG5578	integral membrane protein
N6G78_03825	COG2972	Histidine kinase
N6G78_03830	COG4753	response regulator
N6G78_03830	COG2207	Transcriptional regulator
N6G78_03835	COG1653	transport
N6G78_03840	COG1175	transmembrane transport
N6G78_03845	COG0395	ABC-type sugar transport system, permease component
N6G78_03850	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N6G78_03855	COG2207	Transcriptional regulator
N6G78_03860	COG2755	lipolytic protein G-D-S-L family
N6G78_03870	COG5578	integral membrane protein
N6G78_03875	COG3401	FG-GAP repeat protein
N6G78_03880	COG3401	FG-GAP repeat protein
N6G78_03885	COG2755	lipolytic protein G-D-S-L family
N6G78_03890	COG1874	Beta-galactosidase
N6G78_03900	COG1653	transport
N6G78_03905	COG4209	transmembrane transport
N6G78_03910	COG0395	ABC-type sugar transport system, permease component
N6G78_03915	COG1486	melibiose metabolic process
N6G78_03920	COG2323	membrane
N6G78_03925	COG2329	Antibiotic biosynthesis monooxygenase
N6G78_03930	COG0346	lactoylglutathione lyase activity
N6G78_03945	COG5583	Uncharacterized small protein (DUF2292)
N6G78_03950	COG0670	Belongs to the BI1 family
N6G78_03970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N6G78_03970	COG2124	cytochrome p450
N6G78_03975	COG1368	sulfuric ester hydrolase activity
N6G78_03980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N6G78_03985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N6G78_03990	COG1442	glycosyl transferase family 8
N6G78_03995	COG1216	Glycosyl transferase, family 2
N6G78_04000	COG1442	glycosyl transferase family 8
N6G78_04005	COG2223	nitrite transmembrane transporter activity
N6G78_04010	COG1011	Hydrolase
N6G78_04015	COG0531	amino acid
N6G78_04020	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_04025	COG0840	transmembrane signaling receptor activity
N6G78_04030	COG0488	(ABC) transporter
N6G78_04040	COG0789	Transcriptional regulator
N6G78_04045	COG2814	Major facilitator Superfamily
N6G78_04060	COG0488	(ABC) transporter
N6G78_04065	COG0513	Belongs to the DEAD box helicase family
N6G78_04070	COG0456	acetyltransferase
N6G78_04075	COG2130	NADP-dependent
N6G78_04080	COG1120	ATPase activity
N6G78_04085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N6G78_04090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N6G78_04095	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
N6G78_04110	COG3866	Pectate lyase
N6G78_04115	COG0471	metal ion transport
N6G78_04120	COG3290	protein histidine kinase activity
N6G78_04125	COG4565	transcriptional regulatory protein
N6G78_04130	COG3181	Tripartite tricarboxylate transporter family receptor
N6G78_04140	COG2851	Citrate transporter
N6G78_04145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N6G78_04150	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
N6G78_04155	COG1254	Belongs to the acylphosphatase family
N6G78_04160	COG2258	MOSC domain
N6G78_04180	COG0024	Methionine aminopeptidase
N6G78_04185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N6G78_04185	COG1263	PTS System
N6G78_04190	COG1368	sulfuric ester hydrolase activity
N6G78_04205	COG1115	amino acid carrier protein
N6G78_04210	COG0531	amino acid
N6G78_04225	COG0697	spore germination
N6G78_04230	COG1263	PTS System
N6G78_04230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N6G78_04235	COG0366	Alpha amylase catalytic
N6G78_04240	COG2188	Transcriptional regulator
N6G78_04245	COG0778	Nitroreductase
N6G78_04250	COG0737	Belongs to the 5'-nucleotidase family
N6G78_04255	COG0693	protein deglycase activity
N6G78_04260	COG2814	Major facilitator Superfamily
N6G78_04265	COG4840	Belongs to the UPF0435 family
N6G78_04270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N6G78_04275	COG4980	gas vesicle protein
N6G78_04280	COG1295	ribonuclease BN
N6G78_04285	COG0477	Major facilitator Superfamily
N6G78_04290	COG0387	Pfam Sodium calcium exchanger
N6G78_04300	COG0668	transmembrane transport
N6G78_04305	COG0535	radical SAM domain protein
N6G78_04315	COG0726	polysaccharide deacetylase
N6G78_04320	COG2084	Dehydrogenase
N6G78_04325	COG0598	Magnesium transport protein CorA
N6G78_04330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N6G78_04335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N6G78_04345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N6G78_04350	COG4637	Psort location Cytoplasmic, score
N6G78_04360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N6G78_04365	COG0022	dehydrogenase e1 component
N6G78_04370	COG0508	dehydrogenase complex catalyzes the overall conversion of
N6G78_04375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N6G78_04380	COG3284	Transcriptional regulator
N6G78_04390	COG1742	UPF0060 membrane protein
N6G78_04410	COG4842	Belongs to the WXG100 family
N6G78_04415	COG1486	melibiose metabolic process
N6G78_04420	COG1737	Transcriptional regulator
N6G78_04425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N6G78_04425	COG1263	PTS System
N6G78_04430	COG1132	(ABC) transporter
N6G78_04435	COG1132	(ABC) transporter
N6G78_04440	COG2259	Doxx family
N6G78_04445	COG2514	catechol 2,3-dioxygenase activity
N6G78_04450	COG4585	Histidine kinase
N6G78_04455	COG2197	response regulator
N6G78_04460	COG1131	(ABC) transporter
N6G78_04465	COG1511	domain protein
N6G78_04465	COG0842	Transport permease protein
N6G78_04470	COG0842	Transport permease protein
N6G78_04480	COG1695	Transcriptional regulator
N6G78_04485	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N6G78_04505	COG1131	(ABC) transporter
N6G78_04510	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
N6G78_04515	COG1309	transcriptional regulator
N6G78_04520	COG2814	Major facilitator Superfamily
N6G78_04525	COG2318	DinB family
N6G78_04530	COG2814	Major facilitator Superfamily
N6G78_04535	COG1846	Transcriptional regulator
N6G78_04540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N6G78_04540	COG0392	lysyltransferase activity
N6G78_04545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N6G78_04550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N6G78_04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N6G78_04560	COG0384	phenazine biosynthesis protein PhzF
N6G78_04565	COG0778	Nitroreductase
N6G78_04580	COG1090	epimerase
N6G78_04585	COG2137	regulation of response to DNA damage stimulus
N6G78_04595	COG2814	Major facilitator Superfamily
N6G78_04610	COG3103	Sh3 type 3 domain protein
N6G78_04615	COG5658	integral membrane protein
N6G78_04620	COG0596	Alpha beta hydrolase
N6G78_04625	COG0463	Glycosyl transferase, family 2
N6G78_04630	COG4485	Bacterial membrane protein, YfhO
N6G78_04635	COG1988	membrane-bound metal-dependent
N6G78_04640	COG1194	a g-specific adenine glycosylase
N6G78_04650	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_04665	COG3557	Belongs to the UPF0374 family
N6G78_04670	COG1132	(ABC) transporter
N6G78_04675	COG4129	membrane
N6G78_04680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N6G78_04685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N6G78_04690	COG0735	belongs to the Fur family
N6G78_04800	COG4326	sporulation control protein
N6G78_04810	COG5577	PFAM Coat F domain
N6G78_04815	COG3340	Belongs to the peptidase S51 family
N6G78_04820	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N6G78_04835	COG0753	catalase activity
N6G78_04840	COG1116	anion transmembrane transporter activity
N6G78_04845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N6G78_04850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N6G78_04855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N6G78_04865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N6G78_04875	COG1476	TRANSCRIPTIONal
N6G78_04885	COG3382	B3 4 domain protein
N6G78_04890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N6G78_04900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N6G78_04905	COG0789	Transcriptional regulator
N6G78_04910	COG1664	Polymer-forming cytoskeletal
N6G78_04915	COG1664	Polymer-forming cytoskeletal
N6G78_04920	COG2766	serine protein kinase
N6G78_04925	COG2718	Belongs to the UPF0229 family
N6G78_04930	COG1846	Transcriptional regulator
N6G78_04935	COG1566	PFAM secretion protein HlyD family protein
N6G78_04940	COG2814	Major facilitator Superfamily
N6G78_04945	COG0655	NAD(P)H dehydrogenase (quinone) activity
N6G78_04965	COG1725	Transcriptional regulator
N6G78_04970	COG1131	(ABC) transporter
N6G78_04975	COG1131	(ABC) transporter
N6G78_04980	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N6G78_04985	COG1278	Cold shock
N6G78_04990	COG1464	Belongs to the NlpA lipoprotein family
N6G78_04995	COG3706	GGDEF domain
N6G78_05000	COG1823	symporter activity
N6G78_05020	COG5577	PFAM Coat F domain
N6G78_05025	COG0737	Belongs to the 5'-nucleotidase family
N6G78_05025	COG1525	nuclease
N6G78_05025	COG4085	toxin activity
N6G78_05030	COG3764	Sortase (surface protein transpeptidase)
N6G78_05035	COG0564	pseudouridine synthase activity
N6G78_05045	COG0517	IMP dehydrogenase activity
N6G78_05050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N6G78_05055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N6G78_05055	COG3153	acetyltransferase
N6G78_05060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N6G78_05065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
N6G78_05070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N6G78_05075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N6G78_05080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N6G78_05085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N6G78_05090	COG4585	Histidine kinase
N6G78_05090	COG2203	Gaf domain
N6G78_05095	COG2197	response regulator
N6G78_05100	COG0431	NADPH-dependent FMN reductase
N6G78_05115	COG0791	NLP P60 protein
N6G78_05115	COG1388	LysM domain
N6G78_05120	COG1959	2 iron, 2 sulfur cluster binding
N6G78_05135	COG2719	SpoVR family
N6G78_05140	COG1785	Belongs to the alkaline phosphatase family
N6G78_05145	COG1388	LysM domain
N6G78_05145	COG0791	NLP P60 protein
N6G78_05150	COG0583	DNA-binding transcription factor activity
N6G78_05155	COG0372	Belongs to the citrate synthase family
N6G78_05160	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_05165	COG0531	amino acid
N6G78_05170	COG0733	neurotransmitter:sodium symporter activity
N6G78_05180	COG0456	acetyltransferase
N6G78_05195	COG1595	DNA-templated transcription, initiation
N6G78_05200	COG0667	Aldo Keto reductase
N6G78_05205	COG0204	Acyl-transferase
N6G78_05210	COG1253	flavin adenine dinucleotide binding
N6G78_05215	COG0789	Transcriptional regulator
N6G78_05220	COG0436	Aminotransferase
N6G78_05225	COG1253	flavin adenine dinucleotide binding
N6G78_05230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N6G78_05235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N6G78_05240	COG0584	glycerophosphoryl diester phosphodiesterase
N6G78_05250	COG0668	transmembrane transport
N6G78_05255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N6G78_05260	COG0726	polysaccharide deacetylase
N6G78_05265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N6G78_05270	COG1757	Na H antiporter
N6G78_05275	COG0589	response to stress
N6G78_05285	COG1132	(ABC) transporter
N6G78_05290	COG1132	(ABC) transporter
N6G78_05295	COG0702	epimerase
N6G78_05315	COG0189	ligase activity
N6G78_05320	COG0189	ligase activity
N6G78_05325	COG4399	Belongs to the UPF0754 family
N6G78_05330	COG3679	Belongs to the UPF0342 family
N6G78_05335	COG4335	DNA alkylation repair
N6G78_05340	COG0561	phosphatase activity
N6G78_05345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N6G78_05350	COG0475	glutathione-regulated potassium exporter activity
N6G78_05355	COG0490	domain, Protein
N6G78_05365	COG1024	Enoyl-CoA hydratase
N6G78_05375	COG4152	abc transporter atp-binding protein
N6G78_05380	COG1668	transmembrane transport
N6G78_05385	COG0420	3'-5' exonuclease activity
N6G78_05390	COG4717	serine-type aminopeptidase activity
N6G78_05395	COG3481	metal-dependent phosphohydrolase, HD sub domain
N6G78_05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N6G78_05435	COG1846	Transcriptional regulator
N6G78_05440	COG4980	gas vesicle protein
N6G78_05455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N6G78_05460	COG0537	adenosine 5'-monophosphoramidase activity
N6G78_05465	COG1131	(ABC) transporter
N6G78_05470	COG4473	ABC transporter
N6G78_05480	COG1473	amidohydrolase
N6G78_05485	COG3069	C4-dicarboxylate transmembrane transporter activity
N6G78_05495	COG2329	Antibiotic biosynthesis monooxygenase
N6G78_05500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N6G78_05505	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N6G78_05510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N6G78_05515	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
N6G78_05520	COG1309	transcriptional regulator
N6G78_05525	COG1511	domain protein
N6G78_05530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N6G78_05535	COG4377	Putative membrane peptidase family (DUF2324)
N6G78_05545	COG1363	Peptidase, m42
N6G78_05550	COG4405	Protein conserved in bacteria
N6G78_05555	COG1301	dicarboxylic acid transport
N6G78_05565	COG1234	tRNA 3'-trailer cleavage
N6G78_05570	COG0095	Lipoate-protein ligase
N6G78_05575	COG0702	epimerase
N6G78_05580	COG0318	PFAM AMP-dependent synthetase and ligase
N6G78_05590	COG0501	Belongs to the peptidase M48B family
N6G78_05595	COG1404	Belongs to the peptidase S8 family
N6G78_05605	COG0604	alcohol dehydrogenase
N6G78_05610	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
N6G78_05615	COG0406	alpha-ribazole phosphatase activity
N6G78_05620	COG0183	Belongs to the thiolase family
N6G78_05630	COG1268	BioY protein
N6G78_05635	COG0840	transmembrane signaling receptor activity
N6G78_05640	COG0723	plastoquinol--plastocyanin reductase activity
N6G78_05640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N6G78_05645	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_05655	COG4903	ComK protein
N6G78_05660	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_05670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N6G78_05685	COG0398	Pfam SNARE associated Golgi protein
N6G78_05690	COG0681	Belongs to the peptidase S26 family
N6G78_05695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N6G78_05700	COG1846	Transcriptional regulator
N6G78_05705	COG0738	Major facilitator superfamily
N6G78_05710	COG0673	inositol 2-dehydrogenase activity
N6G78_05715	COG0561	phosphatase activity
N6G78_05720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N6G78_05725	COG1609	Transcriptional regulator
N6G78_05730	COG3180	Ammonia monooxygenase
N6G78_05735	COG2814	Major facilitator Superfamily
N6G78_05735	COG0477	Major facilitator Superfamily
N6G78_05740	COG4533	DNA binding
N6G78_05750	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
N6G78_05755	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
N6G78_05760	COG1074	ATP-dependent DNA helicase activity
N6G78_05765	COG0420	3'-5' exonuclease activity
N6G78_05770	COG0419	ATPase involved in DNA repair
N6G78_05775	COG1403	HNH endonuclease
N6G78_05815	COG5337	Spore coat protein CotH
N6G78_05820	COG0179	Fumarylacetoacetate (FAA) hydrolase
N6G78_05830	COG1404	Belongs to the peptidase S8 family
N6G78_05840	COG0367	asparagine synthase
N6G78_05850	COG0534	Mate efflux family protein
N6G78_05855	COG1917	Cupin 2, conserved barrel domain protein
N6G78_05855	COG2207	Transcriptional regulator
N6G78_05860	COG1609	Transcriptional regulator
N6G78_05865	COG0673	inositol 2-dehydrogenase activity
N6G78_05870	COG2318	DinB family
N6G78_05880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N6G78_05885	COG1357	PFAM Pentapeptide repeats (8 copies)
N6G78_05890	COG2267	carboxylic ester hydrolase activity
N6G78_05895	COG0529	Catalyzes the synthesis of activated sulfate
N6G78_05900	COG2046	Belongs to the sulfate adenylyltransferase family
N6G78_05905	COG0175	sulfate reduction
N6G78_05910	COG2045	Belongs to the ComB family
N6G78_05915	COG1809	phosphosulfolactate synthase activity
N6G78_05920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N6G78_05925	COG4948	Mandelate Racemase Muconate Lactonizing
N6G78_05930	COG2814	Major facilitator Superfamily
N6G78_05935	COG0454	-acetyltransferase
N6G78_05940	COG2153	protein acetylation
N6G78_05945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N6G78_05945	COG0646	methionine synthase
N6G78_05975	COG1695	Transcriptional regulator
N6G78_05990	COG3227	Zinc metalloprotease (Elastase)
N6G78_05995	COG1307	EDD domain protein, DegV family
N6G78_06000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N6G78_06020	COG0561	phosphatase activity
N6G78_06025	COG1073	alpha beta
N6G78_06030	COG2151	metal-sulfur cluster biosynthetic enzyme
N6G78_06040	COG0277	FAD linked oxidase domain protein
N6G78_06045	COG2271	Major facilitator Superfamily
N6G78_06050	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N6G78_06055	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N6G78_06065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N6G78_06070	COG0505	Belongs to the CarA family
N6G78_06075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N6G78_06080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N6G78_06095	COG2267	carboxylic ester hydrolase activity
N6G78_06105	COG1744	ABC transporter substrate-binding protein PnrA-like
N6G78_06120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N6G78_06125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N6G78_06130	COG5504	Zn-dependent protease
N6G78_06135	COG0444	Belongs to the ABC transporter superfamily
N6G78_06140	COG4608	Belongs to the ABC transporter superfamily
N6G78_06150	COG0601	transmembrane transport
N6G78_06155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N6G78_06165	COG0180	Tryptophanyl-tRNA synthetase
N6G78_06170	COG4166	transmembrane transport
N6G78_06175	COG0601	transmembrane transport
N6G78_06180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N6G78_06185	COG0444	Belongs to the ABC transporter superfamily
N6G78_06190	COG4608	Belongs to the ABC transporter superfamily
N6G78_06195	COG2814	Major facilitator Superfamily
N6G78_06200	COG0456	acetyltransferase
N6G78_06205	COG1393	Belongs to the ArsC family
N6G78_06210	COG0861	Integral membrane protein TerC family
N6G78_06220	COG4862	establishment of competence for transformation
N6G78_06230	COG4469	Competence protein
N6G78_06235	COG1164	Oligoendopeptidase f
N6G78_06245	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N6G78_06250	COG2346	COG2346, Truncated hemoglobins
N6G78_06255	COG0741	lytic transglycosylase activity
N6G78_06260	COG4116	CYTH
N6G78_06270	COG2357	RelA SpoT domain protein
N6G78_06275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N6G78_06280	COG0564	pseudouridine synthase activity
N6G78_06285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N6G78_06290	COG0475	glutathione-regulated potassium exporter activity
N6G78_06290	COG0569	domain protein
N6G78_06295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N6G78_06300	COG0352	thiamine-phosphate diphosphorylase activity
N6G78_06305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N6G78_06310	COG2104	thiamine diphosphate biosynthetic process
N6G78_06315	COG2022	thiamine diphosphate biosynthetic process
N6G78_06320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N6G78_06325	COG0351	phosphomethylpyrimidine kinase
N6G78_06330	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N6G78_06385	COG0210	DNA helicase
N6G78_06395	COG2153	protein acetylation
N6G78_06400	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N6G78_06405	COG2382	esterase
N6G78_06410	COG0626	cystathionine gamma-synthase activity
N6G78_06415	COG0626	cystathionine gamma-synthase activity
N6G78_06420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N6G78_06425	COG5505	Protein of unknown function (DUF819)
N6G78_06485	COG0457	Tetratricopeptide repeat
N6G78_06490	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N6G78_06500	COG3711	transcriptional antiterminator
N6G78_06500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N6G78_06505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N6G78_06505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N6G78_06505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N6G78_06510	COG1482	cell wall glycoprotein biosynthetic process
N6G78_06520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N6G78_06530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N6G78_06545	COG0109	protoheme IX farnesyltransferase activity
N6G78_06555	COG0726	polysaccharide deacetylase
N6G78_06570	COG5504	Zn-dependent protease
N6G78_06575	COG2205	protein histidine kinase activity
N6G78_06585	COG3383	formate dehydrogenase (NAD+) activity
N6G78_06590	COG2427	Protein of unknown function (DUF1641)
N6G78_06610	COG2124	cytochrome p450
N6G78_06615	COG1819	glycosyl
N6G78_06625	COG1587	Uroporphyrinogen-III synthase
N6G78_06630	COG0390	transport system, permease component
N6G78_06635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N6G78_06640	COG0697	spore germination
N6G78_06645	COG4297	protein containing double-stranded beta helix domain
N6G78_06655	COG1252	NADH dehydrogenase
N6G78_06660	COG1904	glucuronate isomerase
N6G78_06665	COG2211	Major facilitator Superfamily
N6G78_06670	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N6G78_06675	COG1063	alcohol dehydrogenase
N6G78_06680	COG1312	Catalyzes the dehydration of D-mannonate
N6G78_06685	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_06690	COG2271	Major facilitator Superfamily
N6G78_06695	COG1609	Transcriptional regulator
N6G78_06700	COG0246	Mannitol dehydrogenase
N6G78_06705	COG2721	sulfolactate sulfo-lyase activity
N6G78_06710	COG0730	response to heat
N6G78_06715	COG2318	DinB family
N6G78_06720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N6G78_06725	COG0457	Tetratricopeptide repeat
N6G78_06735	COG2350	Protein conserved in bacteria
N6G78_06740	COG3409	Peptidoglycan-binding domain 1 protein
N6G78_06740	COG5632	N-Acetylmuramoyl-L-alanine amidase
N6G78_06740	COG1388	LysM domain
N6G78_06750	COG4195	phage-related replication protein
N6G78_06755	COG3546	catalase activity
N6G78_06760	COG2856	Zn peptidase
N6G78_06765	COG1396	sequence-specific DNA binding
N6G78_06775	COG1522	sequence-specific DNA binding
N6G78_06780	COG1484	DNA-dependent DNA replication
N6G78_06800	COG1595	DNA-templated transcription, initiation
N6G78_06805	COG5484	DNA packaging
N6G78_06805	COG3728	DNA packaging
N6G78_06810	COG1783	phage Terminase large subunit
N6G78_06815	COG5518	Phage portal protein
N6G78_06820	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N6G78_06825	COG4653	Phage capsid family
N6G78_06875	COG5412	phage tail tape measure protein
N6G78_06875	COG3953	SLT domain
N6G78_06880	COG1652	LysM domain
N6G78_06885	COG4193	domain, Protein
N6G78_06895	COG3628	GPW Gp25 family protein
N6G78_06900	COG3299	homolog of phage Mu protein gp47
N6G78_06905	COG3778	Protein conserved in bacteria
N6G78_06945	COG5632	N-Acetylmuramoyl-L-alanine amidase
N6G78_06945	COG3409	Peptidoglycan-binding domain 1 protein
N6G78_06965	COG0306	phosphate transporter
N6G78_06970	COG1392	Phosphate transport regulator
N6G78_06975	COG0531	amino acid
N6G78_06980	COG0346	lactoylglutathione lyase activity
N6G78_06990	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N6G78_06995	COG0463	Glycosyl transferase, family 2
N6G78_07000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N6G78_07005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N6G78_07010	COG2362	D-Aminopeptidase
N6G78_07015	COG0601	transmembrane transport
N6G78_07025	COG0444	Belongs to the ABC transporter superfamily
N6G78_07030	COG4166	transmembrane transport
N6G78_07035	COG1619	proteins homologs of microcin C7 resistance protein MccF
N6G78_07040	COG4948	Mandelate Racemase Muconate Lactonizing
N6G78_07045	COG0791	NLP P60 protein
N6G78_07050	COG4608	Belongs to the ABC transporter superfamily
N6G78_07055	COG2706	6-phosphogluconolactonase activity
N6G78_07060	COG1834	amidinotransferase
N6G78_07065	COG1607	acyl-coa hydrolase
N6G78_07070	COG1017	nitric oxide dioxygenase activity
N6G78_07070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N6G78_07080	COG2323	membrane
N6G78_07085	COG2318	DinB family
N6G78_07090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N6G78_07095	COG2076	Multidrug Resistance protein
N6G78_07100	COG2076	Multidrug Resistance protein
N6G78_07105	COG0788	formyltetrahydrofolate deformylase activity
N6G78_07110	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N6G78_07115	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N6G78_07120	COG1764	response to oxidative stress
N6G78_07125	COG1846	Transcriptional regulator
N6G78_07130	COG1764	response to oxidative stress
N6G78_07135	COG0590	tRNA wobble adenosine to inosine editing
N6G78_07145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N6G78_07150	COG1404	Belongs to the peptidase S8 family
N6G78_07155	COG1366	Belongs to the anti-sigma-factor antagonist family
N6G78_07160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N6G78_07165	COG1122	ATPase activity
N6G78_07170	COG4721	ABC-type cobalt transport system, permease component
N6G78_07180	COG0745	RESPONSE REGULATOR receiver
N6G78_07185	COG3850	Histidine kinase
N6G78_07185	COG5002	protein histidine kinase activity
N6G78_07190	COG3212	peptidase
N6G78_07195	COG3212	peptidase
N6G78_07210	COG2239	Acts as a magnesium transporter
N6G78_07215	COG0789	Transcriptional regulator
N6G78_07230	COG1846	Transcriptional regulator
N6G78_07240	COG0726	polysaccharide deacetylase
N6G78_07245	COG1408	metallophosphoesterase
N6G78_07255	COG0463	Glycosyl transferase, family 2
N6G78_07260	COG3285	dna ligase
N6G78_07260	COG1793	dna ligase
N6G78_07265	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
N6G78_07270	COG5001	Diguanylate cyclase
N6G78_07270	COG3300	MHYT domain
N6G78_07275	COG0586	Pfam SNARE associated Golgi protein
N6G78_07280	COG0861	Integral membrane protein TerC family
N6G78_07285	COG1191	sigma factor activity
N6G78_07305	COG0501	Belongs to the peptidase M48B family
N6G78_07310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N6G78_07325	COG3594	Acyltransferase
N6G78_07330	COG5002	protein histidine kinase activity
N6G78_07335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N6G78_07345	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N6G78_07350	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
N6G78_07355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N6G78_07360	COG0436	Aminotransferase
N6G78_07365	COG1850	ribulose-bisphosphate carboxylase activity
N6G78_07370	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
N6G78_07375	COG0235	Class ii aldolase
N6G78_07380	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
N6G78_07385	COG3339	Conserved Protein
N6G78_07400	COG3852	Histidine kinase
N6G78_07405	COG1846	Transcriptional regulator
N6G78_07410	COG1360	Flagellar Motor Protein
N6G78_07415	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N6G78_07420	COG0542	response to heat
N6G78_07425	COG3949	Membrane
N6G78_07430	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N6G78_07435	COG0720	synthase
N6G78_07440	COG0602	queuosine metabolic process
N6G78_07445	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N6G78_07450	COG1388	LysM domain
N6G78_07450	COG4641	Protein conserved in bacteria
N6G78_07455	COG1388	LysM domain
N6G78_07460	COG3858	chitin binding
N6G78_07470	COG4873	Protein conserved in bacteria
N6G78_07480	COG3773	Cell wall hydrolase
N6G78_07485	COG2244	polysaccharide biosynthetic process
N6G78_07490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N6G78_07495	COG2217	Heavy metal translocating P-type atpase
N6G78_07505	COG0006	proline dipeptidase activity
N6G78_07510	COG1609	Transcriptional regulator
N6G78_07515	COG3711	transcriptional antiterminator
N6G78_07520	COG2190	(PTS) system
N6G78_07520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N6G78_07520	COG1263	PTS System
N6G78_07525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N6G78_07530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N6G78_07540	COG1533	DNA photolyase activity
N6G78_07545	COG0456	acetyltransferase
N6G78_07550	COG0840	transmembrane signaling receptor activity
N6G78_07555	COG2084	Dehydrogenase
N6G78_07560	COG2340	Cysteine-rich secretory protein family
N6G78_07565	COG0768	penicillin binding
N6G78_07570	COG4191	Histidine kinase
N6G78_07575	COG0436	Aminotransferase
N6G78_07585	COG0784	Response regulator, receiver
N6G78_07585	COG0835	chemotaxis
N6G78_07595	COG2814	Major facilitator Superfamily
N6G78_07600	COG1376	ErfK ybiS ycfS ynhG family protein
N6G78_07605	COG1408	metallophosphoesterase
N6G78_07610	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_07615	COG2200	EAL domain
N6G78_07620	COG4703	Protein of unknown function (DUF1797)
N6G78_07625	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
N6G78_07635	COG0517	IMP dehydrogenase activity
N6G78_07640	COG0583	DNA-binding transcription factor activity
N6G78_07645	COG0716	FMN binding
N6G78_07655	COG0716	FMN binding
N6G78_07660	COG2171	N-acyltransferase activity
N6G78_07665	COG1473	amidohydrolase
N6G78_07675	COG0668	transmembrane transport
N6G78_07680	COG0450	alkyl hydroperoxide reductase
N6G78_07685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N6G78_07700	COG0746	molybdenum cofactor guanylyltransferase activity
N6G78_07705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N6G78_07710	COG0303	'Molybdopterin
N6G78_07715	COG1763	Mo-molybdopterin cofactor biosynthetic process
N6G78_07720	COG0314	molybdopterin synthase activity
N6G78_07725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N6G78_07730	COG1132	(ABC) transporter
N6G78_07735	COG1132	(ABC) transporter
N6G78_07745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N6G78_07750	COG1136	(ABC) transporter
N6G78_07755	COG0577	efflux transmembrane transporter activity
N6G78_07760	COG1349	DNA-binding transcription factor activity
N6G78_07765	COG1105	Belongs to the carbohydrate kinase PfkB family
N6G78_07770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N6G78_07770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N6G78_07770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N6G78_07775	COG0681	Belongs to the peptidase S26 family
N6G78_07785	COG0488	(ABC) transporter
N6G78_07795	COG2309	aminopeptidase activity
N6G78_07805	COG1077	Cell shape determining protein MreB Mrl
N6G78_07810	COG2002	toxin-antitoxin pair type II binding
N6G78_07815	COG3852	Histidine kinase
N6G78_07820	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
N6G78_07820	COG2105	PFAM AIG2 family protein
N6G78_07825	COG0569	domain protein
N6G78_07830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N6G78_07835	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N6G78_07840	COG5503	Protein of unknown function (DUF1447)
N6G78_07845	COG0561	phosphatase activity
N6G78_07850	COG0242	peptide deformylase activity
N6G78_07860	COG0497	DNA recombination
N6G78_07865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N6G78_07870	COG0022	dehydrogenase e1 component
N6G78_07875	COG0508	dehydrogenase complex catalyzes the overall conversion of
N6G78_07880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N6G78_07885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N6G78_07895	COG1982	Orn Lys Arg decarboxylase major
N6G78_07900	COG4476	Belongs to the UPF0223 family
N6G78_07905	COG4493	Belongs to the UPF0637 family
N6G78_07915	COG0483	inositol monophosphate 1-phosphatase activity
N6G78_07925	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
N6G78_07945	COG1595	DNA-templated transcription, initiation
N6G78_07965	COG1217	gtp-binding protein TYPA
N6G78_07975	COG4896	Protein conserved in bacteria
N6G78_07985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N6G78_07990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N6G78_07995	COG2066	Belongs to the glutaminase family
N6G78_08000	COG4838	Belongs to the UPF0358 family
N6G78_08005	COG0772	Belongs to the SEDS family
N6G78_08010	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N6G78_08015	COG1612	heme a metabolic process
N6G78_08020	COG0109	protoheme IX farnesyltransferase activity
N6G78_08025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N6G78_08025	COG2010	Cytochrome c
N6G78_08030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N6G78_08035	COG1845	cytochrome c oxidase, subunit III
N6G78_08040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N6G78_08045	COG3336	cytochrome c oxidase
N6G78_08055	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
N6G78_08060	COG2340	Cysteine-rich secretory protein family
N6G78_08075	COG3679	Belongs to the UPF0342 family
N6G78_08080	COG4471	UPF0298 protein
N6G78_08085	COG0742	ribosomal rna small subunit methyltransferase
N6G78_08090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N6G78_08095	COG3314	Sporulation integral membrane protein YlbJ
N6G78_08100	COG1752	Esterase of the alpha-beta hydrolase superfamily
N6G78_08105	COG3480	Lon protease (S16) C-terminal proteolytic domain
N6G78_08125	COG1399	metal-binding, possibly nucleic acid-binding protein
N6G78_08140	COG0454	-acetyltransferase
N6G78_08145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N6G78_08150	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
N6G78_08155	COG2001	Belongs to the MraZ family
N6G78_08160	COG0275	rRNA processing
N6G78_08165	COG4839	cell division protein FtsL
N6G78_08170	COG0768	penicillin binding
N6G78_08175	COG0768	penicillin binding
N6G78_08180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N6G78_08185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N6G78_08190	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N6G78_08195	COG0772	Belongs to the SEDS family
N6G78_08200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N6G78_08205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N6G78_08210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N6G78_08215	COG3879	Bacterial protein of unknown function (DUF881)
N6G78_08220	COG3879	Bacterial protein of unknown function (DUF881)
N6G78_08225	COG3856	small basic protein
N6G78_08230	COG0849	cell division
N6G78_08235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N6G78_08240	COG4412	M6 family metalloprotease domain protein
N6G78_08240	COG1404	Belongs to the peptidase S8 family
N6G78_08250	COG1191	sigma factor activity
N6G78_08255	COG1191	sigma factor activity
N6G78_08260	COG1119	ATPase activity
N6G78_08265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N6G78_08270	COG1873	PFAM PRC-barrel domain
N6G78_08275	COG1496	oxidoreductase activity
N6G78_08280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N6G78_08285	COG1799	cell septum assembly
N6G78_08290	COG0762	integral membrane protein
N6G78_08295	COG2302	S4 RNA-binding domain
N6G78_08300	COG3599	regulation of cell shape
N6G78_08305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N6G78_08310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N6G78_08315	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N6G78_08320	COG0564	pseudouridine synthase activity
N6G78_08325	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
N6G78_08330	COG2233	PERMEase
N6G78_08335	COG0540	Belongs to the ATCase OTCase family
N6G78_08340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N6G78_08345	COG0505	Belongs to the CarA family
N6G78_08350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N6G78_08355	COG0543	2 iron, 2 sulfur cluster binding
N6G78_08360	COG0167	dihydroorotate dehydrogenase activity
N6G78_08365	COG0284	orotidine-5'-phosphate decarboxylase activity
N6G78_08370	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N6G78_08375	COG0175	sulfate reduction
N6G78_08380	COG0306	phosphate transporter
N6G78_08385	COG2046	Belongs to the sulfate adenylyltransferase family
N6G78_08390	COG0529	Catalyzes the synthesis of activated sulfate
N6G78_08395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N6G78_08400	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
N6G78_08405	COG1648	precorrin-2 dehydrogenase activity
N6G78_08410	COG1293	RNA-binding protein homologous to eukaryotic snRNP
N6G78_08415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N6G78_08420	COG1561	YicC-like family, N-terminal region
N6G78_08430	COG0194	GDP metabolic process
N6G78_08435	COG1758	RNA polymerase activity
N6G78_08440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N6G78_08445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N6G78_08450	COG0242	peptide deformylase activity
N6G78_08455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N6G78_08460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N6G78_08460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N6G78_08465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N6G78_08470	COG0631	protein serine/threonine phosphatase activity
N6G78_08475	COG2815	serine threonine protein kinase
N6G78_08475	COG0515	serine threonine protein kinase
N6G78_08480	COG1162	GTPase activity
N6G78_08485	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N6G78_08490	COG1564	THIamine pyrophosphokinase
N6G78_08500	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N6G78_08505	COG1302	Protein conserved in bacteria
N6G78_08510	COG1461	Dihydroxyacetone kinase
N6G78_08515	COG1760	l-serine dehydratase
N6G78_08520	COG1760	l-serine dehydratase
N6G78_08525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N6G78_08530	COG2050	protein possibly involved in aromatic compounds catabolism
N6G78_08530	COG1349	DNA-binding transcription factor activity
N6G78_08535	COG0416	fatty acid biosynthetic process
N6G78_08540	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N6G78_08545	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_08555	COG0571	ribonuclease III activity
N6G78_08560	COG1196	nuclear chromosome segregation
N6G78_08565	COG0552	protein localization to endoplasmic reticulum
N6G78_08575	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
N6G78_08580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N6G78_08585	COG0228	four-way junction DNA binding
N6G78_08590	COG1837	Belongs to the UPF0109 family
N6G78_08600	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N6G78_08605	COG0336	Belongs to the RNA methyltransferase TrmD family
N6G78_08610	COG0335	large ribosomal subunit rRNA binding
N6G78_08615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N6G78_08620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N6G78_08630	COG2257	FlhB HrpN YscU SpaS Family
N6G78_08635	COG0045	succinate-CoA ligase (ADP-forming) activity
N6G78_08640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N6G78_08650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N6G78_08655	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
N6G78_08660	COG4974	Belongs to the 'phage' integrase family
N6G78_08665	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N6G78_08670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N6G78_08675	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N6G78_08680	COG1815	bacterial-type flagellum-dependent cell motility
N6G78_08685	COG1558	bacterial-type flagellum-dependent cell motility
N6G78_08690	COG1677	Flagellar hook-basal body complex protein FliE
N6G78_08695	COG1766	The M ring may be actively involved in energy transduction
N6G78_08700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N6G78_08705	COG1317	bacterial-type flagellum organization
N6G78_08710	COG1157	protein secretion by the type III secretion system
N6G78_08715	COG2882	bacterial-type flagellum organization
N6G78_08720	COG3334	PFAM MgtE intracellular
N6G78_08725	COG3144	bacterial-type flagellum assembly
N6G78_08730	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N6G78_08735	COG4786	Flagellar basal body rod
N6G78_08740	COG1582	Flagellar protein (FlbD)
N6G78_08745	COG1580	Controls the rotational direction of flagella during chemotaxis
N6G78_08750	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N6G78_08755	COG1776	CheC inhibitor of MCP methylation
N6G78_08755	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N6G78_08760	COG2201	protein-glutamate methylesterase activity
N6G78_08765	COG3190	flagellar
N6G78_08770	COG1338	Plays a role in the flagellum-specific transport system
N6G78_08775	COG1987	bacterial-type flagellum assembly
N6G78_08780	COG1684	flagellar biosynthetic protein fliR
N6G78_08785	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N6G78_08790	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N6G78_08795	COG1419	protein localization to endoplasmic reticulum
N6G78_08800	COG0455	bacterial-type flagellum organization
N6G78_08805	COG2201	protein-glutamate methylesterase activity
N6G78_08810	COG0643	Histidine kinase
N6G78_08810	COG2198	Histidine kinase
N6G78_08815	COG0835	chemotaxis
N6G78_08820	COG1776	CheC inhibitor of MCP methylation
N6G78_08825	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N6G78_08830	COG1191	sigma factor activity
N6G78_08840	COG0052	Belongs to the universal ribosomal protein uS2 family
N6G78_08845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N6G78_08850	COG0528	UMP kinase activity
N6G78_08855	COG0233	cytoplasmic translational termination
N6G78_08860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N6G78_08865	COG4589	Belongs to the CDS family
N6G78_08870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N6G78_08875	COG0750	zinc metalloprotease
N6G78_08880	COG0442	prolyl-tRNA aminoacylation
N6G78_08885	COG2176	DNA-directed DNA polymerase activity
N6G78_08890	COG0779	Required for maturation of 30S ribosomal subunits
N6G78_08895	COG0195	Participates in both transcription termination and antitermination
N6G78_08900	COG2740	Nucleic-acid-binding protein implicated in transcription termination
N6G78_08905	COG1358	cellular component organization or biogenesis
N6G78_08910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N6G78_08915	COG1550	Protein conserved in bacteria
N6G78_08920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N6G78_08925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N6G78_08930	COG0196	riboflavin kinase activity
N6G78_08935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N6G78_08940	COG1185	polyribonucleotide nucleotidyltransferase activity
N6G78_08945	COG0726	polysaccharide deacetylase
N6G78_08950	COG0612	Peptidase, M16
N6G78_08955	COG1873	PFAM PRC-barrel domain
N6G78_08960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N6G78_08965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N6G78_08970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N6G78_08975	COG0527	aspartate kinase activity
N6G78_08980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N6G78_08985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N6G78_08990	COG0740	serine-type endopeptidase activity
N6G78_09000	COG4980	gas vesicle protein
N6G78_09000	COG1674	ftsk spoiiie
N6G78_09005	COG2188	Transcriptional regulator
N6G78_09010	COG2814	Major facilitator Superfamily
N6G78_09015	COG0612	Peptidase, M16
N6G78_09020	COG0612	Peptidase, M16
N6G78_09025	COG0300	oxidoreductase activity
N6G78_09040	COG1426	Protein conserved in bacteria
N6G78_09045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N6G78_09050	COG1546	Belongs to the CinA family
N6G78_09050	COG1058	Belongs to the CinA family
N6G78_09055	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N6G78_09060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N6G78_09065	COG1418	mRNA catabolic process
N6G78_09070	COG1692	metallophosphoesterase
N6G78_09075	COG2359	stage V sporulation protein S
N6G78_09080	COG1063	alcohol dehydrogenase
N6G78_09085	COG0156	8-amino-7-oxononanoate synthase activity
N6G78_09090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N6G78_09095	COG4550	Control of competence regulator ComK, YlbF/YmcA
N6G78_09105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N6G78_09110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N6G78_09125	COG3226	Transcriptional regulator
N6G78_09130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N6G78_09140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N6G78_09145	COG3321	synthase
N6G78_09150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N6G78_09150	COG2070	2-Nitropropane dioxygenase
N6G78_09155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N6G78_09160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N6G78_09165	COG3425	synthase
N6G78_09170	COG1024	Enoyl-CoA hydratase
N6G78_09175	COG1024	Enoyl-CoA hydratase
N6G78_09180	COG3321	synthase
N6G78_09180	COG0318	PFAM AMP-dependent synthetase and ligase
N6G78_09180	COG0300	oxidoreductase activity
N6G78_09180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_09180	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_09185	COG3321	synthase
N6G78_09185	COG4221	oxidoreductase activity
N6G78_09185	COG0300	oxidoreductase activity
N6G78_09185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N6G78_09190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N6G78_09190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_09190	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_09190	COG3321	synthase
N6G78_09190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N6G78_09195	COG4221	oxidoreductase activity
N6G78_09195	COG3321	synthase
N6G78_09195	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_09200	COG3321	synthase
N6G78_09200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N6G78_09200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N6G78_09200	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N6G78_09205	COG2124	cytochrome p450
N6G78_09215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N6G78_09220	COG1404	Belongs to the peptidase S8 family
N6G78_09230	COG4195	phage-related replication protein
N6G78_09235	COG1764	response to oxidative stress
N6G78_09240	COG2076	Multidrug Resistance protein
N6G78_09245	COG2076	Multidrug Resistance protein
N6G78_09260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N6G78_09265	COG1923	regulation of RNA biosynthetic process
N6G78_09280	COG1780	Probably involved in ribonucleotide reductase function
N6G78_09285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N6G78_09290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N6G78_09295	COG4112	unkown
N6G78_09300	COG0860	N-Acetylmuramoyl-L-alanine amidase
N6G78_09310	COG0464	growth
N6G78_09315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N6G78_09320	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
N6G78_09325	COG0789	Transcriptional regulator
N6G78_09330	COG0174	glutamine synthetase
N6G78_09380	COG4282	regulation of fungal-type cell wall biogenesis
N6G78_09390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N6G78_09405	COG3655	Transcriptional regulator
N6G78_09435	COG2211	Major facilitator Superfamily
N6G78_09440	COG3507	Belongs to the glycosyl hydrolase 43 family
N6G78_09445	COG1940	carbohydrate kinase activity
N6G78_09450	COG2115	Belongs to the xylose isomerase family
N6G78_09455	COG1070	Carbohydrate kinase
N6G78_09465	COG1525	nuclease
N6G78_09470	COG2814	Major facilitator Superfamily
N6G78_09475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N6G78_09485	COG0756	dUTP diphosphatase activity
N6G78_09500	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
N6G78_09530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N6G78_09545	COG3832	glyoxalase III activity
N6G78_09560	COG0697	spore germination
N6G78_09565	COG0531	amino acid
N6G78_09595	COG4195	phage-related replication protein
N6G78_09605	COG0346	lactoylglutathione lyase activity
N6G78_09615	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N6G78_09620	COG1388	LysM domain
N6G78_09625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N6G78_09630	COG4224	UPF0291 protein
N6G78_09635	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N6G78_09645	COG3763	UPF0154 protein
N6G78_09655	COG0785	Cytochrome C biogenesis protein
N6G78_09660	COG2201	protein-glutamate methylesterase activity
N6G78_09665	COG4846	Membrane protein involved in cytochrome C biogenesis
N6G78_09675	COG0071	Belongs to the small heat shock protein (HSP20) family
N6G78_09690	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N6G78_09695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N6G78_09715	COG0824	Thioesterase
N6G78_09725	COG4841	protein insertion into membrane
N6G78_09730	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N6G78_09735	COG1832	CoA-binding protein
N6G78_09740	COG0187	DNA topoisomerase II activity
N6G78_09745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N6G78_09760	COG1115	amino acid carrier protein
N6G78_09765	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
N6G78_09785	COG5520	Belongs to the glycosyl hydrolase 30 family
N6G78_09790	COG3507	Belongs to the glycosyl hydrolase 43 family
N6G78_09795	COG2246	polysaccharide biosynthetic process
N6G78_09800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N6G78_09805	COG0586	Pfam SNARE associated Golgi protein
N6G78_09810	COG2404	hydrolase activity, acting on ester bonds
N6G78_09815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N6G78_09820	COG1024	Enoyl-CoA hydratase
N6G78_09825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N6G78_09830	COG0511	ligase activity, forming carbon-carbon bonds
N6G78_09835	COG0439	Biotin carboxylase
N6G78_09840	COG0318	PFAM AMP-dependent synthetase and ligase
N6G78_09845	COG1960	acyl-CoA dehydrogenase activity
N6G78_09860	COG1649	PFAM Uncharacterised BCR, COG1649
N6G78_09870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_09870	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N6G78_09875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_09880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_09885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_09890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_09895	COG2027	D-alanyl-D-alanine carboxypeptidase
N6G78_09900	COG2017	converts alpha-aldose to the beta-anomer
N6G78_09905	COG0534	Mate efflux family protein
N6G78_09920	COG0582	viral genome integration into host DNA
N6G78_09925	COG0166	Belongs to the GPI family
N6G78_09930	COG0405	Gamma-glutamyltransferase
N6G78_09935	COG0583	DNA-binding transcription factor activity
N6G78_09940	COG0604	alcohol dehydrogenase
N6G78_09945	COG0493	'glutamate synthase
N6G78_09950	COG0070	glutamate synthase
N6G78_09950	COG0069	glutamate synthase activity
N6G78_09950	COG0067	glutamate synthase
N6G78_09955	COG0583	DNA-binding transcription factor activity
N6G78_09960	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N6G78_09965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N6G78_09975	COG0300	oxidoreductase activity
N6G78_09980	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N6G78_09990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N6G78_09995	COG2814	Major facilitator Superfamily
N6G78_10000	COG1070	Carbohydrate kinase
N6G78_10005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N6G78_10010	COG0243	molybdopterin cofactor binding
N6G78_10035	COG5278	phosphoserine phosphatase activity
N6G78_10035	COG0840	transmembrane signaling receptor activity
N6G78_10040	COG2368	4-hydroxyphenylacetate
N6G78_10045	COG4305	rare lipoprotein A
N6G78_10050	COG3619	membrane
N6G78_10055	COG3866	Pectate lyase
N6G78_10070	COG2140	Oxalate decarboxylase
N6G78_10100	COG2720	vancomycin resistance protein
N6G78_10115	COG3739	integral membrane protein
N6G78_10120	COG0583	DNA-binding transcription factor activity
N6G78_10125	COG0697	spore germination
N6G78_10135	COG0693	protein deglycase activity
N6G78_10140	COG2367	Beta-lactamase
N6G78_10155	COG3848	Pyruvate phosphate dikinase
N6G78_10155	COG0574	Belongs to the PEP-utilizing enzyme family
N6G78_10160	COG0726	polysaccharide deacetylase
N6G78_10205	COG5444	nuclease activity
N6G78_10210	COG4282	regulation of fungal-type cell wall biogenesis
N6G78_10215	COG1231	oxidoreductase activity
N6G78_10220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N6G78_10225	COG0662	Cupin 2, conserved barrel domain protein
N6G78_10225	COG2207	Transcriptional regulator
N6G78_10240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N6G78_10245	COG3708	Transcriptional regulator
N6G78_10250	COG2378	regulation of single-species biofilm formation
N6G78_10260	COG0640	Transcriptional regulator
N6G78_10265	COG0741	lytic transglycosylase activity
N6G78_10270	COG2322	membrane
N6G78_10285	COG1619	proteins homologs of microcin C7 resistance protein MccF
N6G78_10290	COG3239	Fatty acid desaturase
N6G78_10295	COG4585	Histidine kinase
N6G78_10300	COG2197	response regulator
N6G78_10305	COG1388	LysM domain
N6G78_10305	COG3584	3D domain protein
N6G78_10310	COG0514	ATP-dependent DNA helicase (RecQ)
N6G78_10320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N6G78_10325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N6G78_10340	COG0071	Belongs to the small heat shock protein (HSP20) family
N6G78_10365	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_10370	COG1657	PFAM Prenyltransferase squalene oxidase
N6G78_10375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N6G78_10380	COG0733	neurotransmitter:sodium symporter activity
N6G78_10385	COG0385	Bile acid
N6G78_10390	COG0508	dehydrogenase complex catalyzes the overall conversion of
N6G78_10395	COG0567	Dehydrogenase, E1 component
N6G78_10400	COG4548	von Willebrand factor, type A
N6G78_10405	COG0714	Associated with various cellular activities
N6G78_10410	COG2032	superoxide dismutase activity
N6G78_10415	COG1388	LysM domain
N6G78_10415	COG0791	NLP P60 protein
N6G78_10420	COG1819	glycosyl
N6G78_10425	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N6G78_10430	COG0534	Mate efflux family protein
N6G78_10435	COG1366	Belongs to the anti-sigma-factor antagonist family
N6G78_10440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N6G78_10445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N6G78_10455	COG2962	Rard protein
N6G78_10470	COG2610	gluconate transmembrane transporter activity
N6G78_10475	COG1942	4-Oxalocrotonate Tautomerase
N6G78_10480	COG1733	regulation of RNA biosynthetic process
N6G78_10485	COG0778	Nitroreductase
N6G78_10490	COG0400	carboxylic ester hydrolase activity
N6G78_10495	COG0346	lactoylglutathione lyase activity
N6G78_10505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N6G78_10510	COG0793	Belongs to the peptidase S41A family
N6G78_10510	COG3409	Peptidoglycan-binding domain 1 protein
N6G78_10515	COG2226	methyltransferase
N6G78_10525	COG1876	peptidase activity
N6G78_10530	COG0813	purine-nucleoside phosphorylase activity
N6G78_10545	COG0671	phosphoesterase, PA-phosphatase related
N6G78_10565	COG4479	Belongs to the UPF0346 family
N6G78_10575	COG1509	lysine 2,3-aminomutase activity
N6G78_10580	COG0456	acetyltransferase
N6G78_10585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N6G78_10590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N6G78_10595	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N6G78_10600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N6G78_10615	COG0456	acetyltransferase
N6G78_10620	COG0463	Glycosyl transferase, family 2
N6G78_10635	COG4641	Protein conserved in bacteria
N6G78_10640	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
N6G78_10645	COG1086	Polysaccharide biosynthesis protein
N6G78_10650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N6G78_10655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N6G78_10660	COG1846	Transcriptional regulator
N6G78_10665	COG0534	Mate efflux family protein
N6G78_10675	COG4698	Protein conserved in bacteria
N6G78_10680	COG2755	lipolytic protein G-D-S-L family
N6G78_10685	COG1999	signal sequence binding
N6G78_10695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N6G78_10700	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N6G78_10705	COG1272	protein, Hemolysin III
N6G78_10710	COG0204	Acyl-transferase
N6G78_10715	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N6G78_10720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
N6G78_10725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N6G78_10735	COG2136	Putative SAM-dependent methyltransferase
N6G78_10735	COG2521	methyltransferase
N6G78_10745	COG0129	dihydroxy-acid dehydratase activity
N6G78_10755	COG1413	lyase activity
N6G78_10760	COG1418	mRNA catabolic process
N6G78_10765	COG0386	Belongs to the glutathione peroxidase family
N6G78_10770	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
N6G78_10775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N6G78_10785	COG1278	Cold shock
N6G78_10805	COG0328	RNA-DNA hybrid ribonuclease activity
N6G78_10810	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N6G78_10815	COG0328	RNA-DNA hybrid ribonuclease activity
N6G78_10825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N6G78_10840	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N6G78_10850	COG1755	Isoprenylcysteine carboxyl methyltransferase
N6G78_10855	COG3424	synthase
N6G78_10860	COG2233	PERMEase
N6G78_10865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N6G78_10870	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N6G78_10880	COG0800	Aldolase
N6G78_10885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N6G78_10890	COG1609	Transcriptional regulator
N6G78_10895	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
N6G78_10900	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_10905	COG1199	ATP-dependent helicase activity
N6G78_10920	COG0116	Belongs to the methyltransferase superfamily
N6G78_10935	COG4474	Belongs to the UPF0398 family
N6G78_10950	COG3359	exonuclease
N6G78_10955	COG1205	dead DEAH box helicase
N6G78_10955	COG1111	helicase
N6G78_10960	COG2190	(PTS) system
N6G78_10965	COG0071	Belongs to the small heat shock protein (HSP20) family
N6G78_11000	COG3331	DNA recombination
N6G78_11005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N6G78_11005	COG4499	WXG100 protein secretion system (Wss), protein YukC
N6G78_11015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N6G78_11020	COG3935	DnaD domain protein
N6G78_11025	COG0017	Asparaginyl-tRNA synthetase
N6G78_11030	COG0436	Aminotransferase
N6G78_11035	COG5353	protein conserved in bacteria
N6G78_11045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N6G78_11045	COG1199	ATP-dependent helicase activity
N6G78_11050	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
N6G78_11055	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N6G78_11060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N6G78_11065	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
N6G78_11065	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
N6G78_11070	COG0617	tRNA 3'-terminal CCA addition
N6G78_11075	COG0438	transferase activity, transferring glycosyl groups
N6G78_11080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N6G78_11085	COG1803	Methylglyoxal synthase
N6G78_11090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N6G78_11095	COG1694	Mazg nucleotide pyrophosphohydrolase
N6G78_11100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N6G78_11110	COG4347	Protein of unknown function (DUF1405)
N6G78_11115	COG2010	Cytochrome c
N6G78_11115	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N6G78_11120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N6G78_11125	COG0723	plastoquinol--plastocyanin reductase activity
N6G78_11135	COG5582	Belongs to the UPF0302 family
N6G78_11140	COG0457	Tetratricopeptide repeat
N6G78_11145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N6G78_11150	COG0287	Prephenate dehydrogenase
N6G78_11155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N6G78_11160	COG0159	tryptophan synthase activity
N6G78_11165	COG0133	tryptophan synthase activity
N6G78_11170	COG0135	phosphoribosylanthranilate isomerase activity
N6G78_11180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N6G78_11185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N6G78_11190	COG4401	Chorismate mutase type I
N6G78_11195	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N6G78_11200	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N6G78_11205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N6G78_11210	COG0105	UTP biosynthetic process
N6G78_11215	COG0142	geranyltranstransferase activity
N6G78_11220	COG2226	methyltransferase
N6G78_11225	COG0142	geranyltranstransferase activity
N6G78_11235	COG0302	gtp cyclohydrolase
N6G78_11240	COG0776	regulation of translation
N6G78_11245	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N6G78_11260	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N6G78_11265	COG1160	GTP binding
N6G78_11290	COG1304	FMN binding
N6G78_11295	COG0539	negative regulation of cytoplasmic translation
N6G78_11300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N6G78_11310	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
N6G78_11315	COG2959	enzyme of heme biosynthesis
N6G78_11320	COG3409	Peptidoglycan-binding domain 1 protein
N6G78_11320	COG3773	Cell wall hydrolase
N6G78_11325	COG2339	peptidase activity
N6G78_11330	COG0492	ferredoxin-NADP+ reductase activity
N6G78_11335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N6G78_11340	COG4862	establishment of competence for transformation
N6G78_11345	COG1408	metallophosphoesterase
N6G78_11355	COG1388	LysM domain
N6G78_11360	COG1266	CAAX protease self-immunity
N6G78_11365	COG0514	ATP-dependent DNA helicase (RecQ)
N6G78_11370	COG4955	Helix-turn-helix domain
N6G78_11375	COG1141	Ferredoxin
N6G78_11380	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
N6G78_11385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N6G78_11390	COG0710	3-dehydroquinate dehydratase activity
N6G78_11400	COG1595	DNA-templated transcription, initiation
N6G78_11405	COG5002	protein histidine kinase activity
N6G78_11410	COG0745	RESPONSE REGULATOR receiver
N6G78_11415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N6G78_11420	COG1333	cytochrome c biogenesis protein
N6G78_11425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N6G78_11430	COG1187	pseudouridine synthase activity
N6G78_11435	COG0700	Nucleoside recognition
N6G78_11440	COG2715	membrane protein required for spore maturation
N6G78_11445	COG1686	Belongs to the peptidase S11 family
N6G78_11455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N6G78_11460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N6G78_11465	COG1547	Domain of unknown function (DUF309)
N6G78_11470	COG0456	acetyltransferase
N6G78_11475	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N6G78_11480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N6G78_11480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N6G78_11485	COG0307	riboflavin synthase, alpha
N6G78_11490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N6G78_11490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N6G78_11500	COG0681	Belongs to the peptidase S26 family
N6G78_11515	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
N6G78_11525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N6G78_11530	COG4086	secreted protein
N6G78_11535	COG0019	diaminopimelate decarboxylase activity
N6G78_11540	COG0697	spore germination
N6G78_11555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N6G78_11575	COG1191	sigma factor activity
N6G78_11580	COG2172	sigma factor antagonist activity
N6G78_11585	COG1366	Belongs to the anti-sigma-factor antagonist family
N6G78_11590	COG1686	Belongs to the peptidase S11 family
N6G78_11595	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
N6G78_11600	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N6G78_11605	COG4974	Belongs to the 'phage' integrase family
N6G78_11615	COG0735	belongs to the Fur family
N6G78_11620	COG1300	Membrane
N6G78_11630	COG0281	malic enzyme
N6G78_11635	COG1757	Na H antiporter
N6G78_11640	COG1027	Aspartate ammonia-lyase
N6G78_11645	COG0252	asparaginase activity
N6G78_11650	COG1396	sequence-specific DNA binding
N6G78_11655	COG1379	DNA repair
N6G78_11660	COG0494	nUDIX hydrolase
N6G78_11670	COG0667	Aldo Keto reductase
N6G78_11680	COG1073	alpha beta
N6G78_11690	COG4918	Iron-sulphur cluster biosynthesis
N6G78_11695	COG0456	acetyltransferase
N6G78_11695	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N6G78_11700	COG2329	Antibiotic biosynthesis monooxygenase
N6G78_11705	COG0456	acetyltransferase
N6G78_11715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N6G78_11725	COG2211	Major facilitator Superfamily
N6G78_11735	COG0346	lactoylglutathione lyase activity
N6G78_11740	COG1072	(Pantothenic acid kinase))
N6G78_11745	COG3048	D-serine ammonia-lyase activity
N6G78_11750	COG0300	oxidoreductase activity
N6G78_11755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N6G78_11760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N6G78_11765	COG4187	Peptidase family M20/M25/M40
N6G78_11770	COG1902	pentaerythritol trinitrate reductase activity
N6G78_11775	COG0596	Alpha beta hydrolase
N6G78_11785	COG1234	tRNA 3'-trailer cleavage
N6G78_11790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N6G78_11795	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N6G78_11800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N6G78_11810	COG0706	membrane insertase activity
N6G78_11815	COG3361	conserved protein (COG2071)
N6G78_11820	COG2195	Cleaves the N-terminal amino acid of tripeptides
N6G78_11825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N6G78_11830	COG0346	lactoylglutathione lyase activity
N6G78_11840	COG1376	ErfK ybiS ycfS ynhG family protein
N6G78_11845	COG4129	membrane
N6G78_11850	COG1126	abc transporter atp-binding protein
N6G78_11855	COG0765	amino acid transport
N6G78_11860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N6G78_11870	COG1597	lipid kinase activity
N6G78_11875	COG2814	Major facilitator Superfamily
N6G78_11880	COG4978	Transcriptional regulator
N6G78_11880	COG0789	Transcriptional regulator
N6G78_11885	COG0508	dehydrogenase complex catalyzes the overall conversion of
N6G78_11890	COG0022	dehydrogenase e1 component
N6G78_11895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N6G78_11900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N6G78_11905	COG3426	butyrate kinase activity
N6G78_11910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N6G78_11915	COG0280	phosphate acetyltransferase
N6G78_11920	COG3829	transcription factor binding
N6G78_11920	COG3290	protein histidine kinase activity
N6G78_11930	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N6G78_11935	COG2079	MmgE PrpD family protein
N6G78_11940	COG0372	Belongs to the citrate synthase family
N6G78_11945	COG1960	acyl-CoA dehydrogenase activity
N6G78_11950	COG1250	3-hydroxyacyl-CoA dehydrogenase
N6G78_11955	COG0183	Belongs to the thiolase family
N6G78_11960	COG0584	glycerophosphoryl diester phosphodiesterase
N6G78_11965	COG0860	N-Acetylmuramoyl-L-alanine amidase
N6G78_11980	COG1902	pentaerythritol trinitrate reductase activity
N6G78_11985	COG0745	RESPONSE REGULATOR receiver
N6G78_11990	COG0750	zinc metalloprotease
N6G78_11995	COG0497	DNA recombination
N6G78_12000	COG1438	arginine binding
N6G78_12005	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
N6G78_12010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N6G78_12015	COG0142	geranyltranstransferase activity
N6G78_12020	COG1722	exodeoxyribonuclease VII activity
N6G78_12025	COG1570	exodeoxyribonuclease VII activity
N6G78_12030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N6G78_12035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N6G78_12040	COG1302	Protein conserved in bacteria
N6G78_12045	COG0439	Biotin carboxylase
N6G78_12050	COG0511	ligase activity, forming carbon-carbon bonds
N6G78_12090	COG3854	ATPases associated with a variety of cellular activities
N6G78_12100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N6G78_12105	COG0006	proline dipeptidase activity
N6G78_12110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N6G78_12120	COG3872	metal-dependent enzyme
N6G78_12130	COG1752	Esterase of the alpha-beta hydrolase superfamily
N6G78_12135	COG1321	iron dependent repressor
N6G78_12140	COG0095	Lipoate-protein ligase
N6G78_12145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N6G78_12150	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N6G78_12155	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N6G78_12160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N6G78_12165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N6G78_12180	COG1396	sequence-specific DNA binding
N6G78_12190	COG0681	Belongs to the peptidase S26 family
N6G78_12215	COG4940	Competence protein ComGF
N6G78_12225	COG4970	Tfp pilus assembly protein FimT
N6G78_12230	COG4537	Required for transformation and DNA binding
N6G78_12235	COG1459	type II secretion system
N6G78_12240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N6G78_12245	COG0598	Magnesium transport protein CorA
N6G78_12250	COG1253	flavin adenine dinucleotide binding
N6G78_12255	COG1366	Belongs to the anti-sigma-factor antagonist family
N6G78_12265	COG1393	Belongs to the ArsC family
N6G78_12275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N6G78_12285	COG0011	TIGRFAM Protein of
N6G78_12295	COG2866	Carboxypeptidase
N6G78_12300	COG1368	sulfuric ester hydrolase activity
N6G78_12305	COG1940	carbohydrate kinase activity
N6G78_12310	COG4483	Protein conserved in bacteria
N6G78_12315	COG0705	Rhomboid family
N6G78_12315	COG0457	Tetratricopeptide repeat
N6G78_12325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N6G78_12335	COG0438	transferase activity, transferring glycosyl groups
N6G78_12350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N6G78_12355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N6G78_12360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N6G78_12365	COG0581	inorganic phosphate transmembrane transporter activity
N6G78_12370	COG0573	inorganic phosphate transmembrane transporter activity
N6G78_12375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N6G78_12380	COG0768	penicillin binding
N6G78_12385	COG0477	Major facilitator Superfamily
N6G78_12390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N6G78_12395	COG2839	Protein conserved in bacteria
N6G78_12400	COG5521	maltodextrose utilization protein MalA
N6G78_12405	COG1388	LysM domain
N6G78_12410	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N6G78_12415	COG4709	membrane
N6G78_12420	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
N6G78_12425	COG0735	belongs to the Fur family
N6G78_12430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N6G78_12440	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N6G78_12445	COG0513	Belongs to the DEAD box helicase family
N6G78_12455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N6G78_12460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N6G78_12465	COG2384	SAM-dependent methyltransferase
N6G78_12470	COG2010	Cytochrome c
N6G78_12475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N6G78_12480	COG0358	DNA primase activity
N6G78_12485	COG1671	Belongs to the UPF0178 family
N6G78_12490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N6G78_12495	COG0517	IMP dehydrogenase activity
N6G78_12500	COG0751	glycine-tRNA ligase activity
N6G78_12505	COG0752	glycyl-tRNA synthetase alpha subunit
N6G78_12510	COG1381	Involved in DNA repair and RecF pathway recombination
N6G78_12520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N6G78_12525	COG0295	cytidine deaminase activity
N6G78_12530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N6G78_12535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N6G78_12540	COG1480	7TM receptor with intracellular HD hydrolase
N6G78_12545	COG1702	phosphate starvation-inducible protein PhoH
N6G78_12550	COG0561	phosphatase activity
N6G78_12565	COG4864	UPF0365 protein
N6G78_12570	COG1030	water channel activity
N6G78_12575	COG1610	YqeY-like protein
N6G78_12585	COG1283	sodium-dependent phosphate transmembrane transporter activity
N6G78_12590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N6G78_12595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N6G78_12600	COG2264	protein methyltransferase activity
N6G78_12605	COG0484	heat shock protein binding
N6G78_12610	COG0443	Heat shock 70 kDa protein
N6G78_12615	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N6G78_12620	COG1420	regulation of RNA biosynthetic process
N6G78_12625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N6G78_12630	COG0481	GTPase activity
N6G78_12640	COG0860	N-Acetylmuramoyl-L-alanine amidase
N6G78_12645	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
N6G78_12650	COG0268	Binds directly to 16S ribosomal RNA
N6G78_12655	COG1466	dna polymerase III delta subunit
N6G78_12670	COG2333	competence protein COMEC
N6G78_12670	COG0658	competence protein
N6G78_12675	COG2131	deaminase
N6G78_12680	COG1596	polysaccharide export
N6G78_12680	COG1555	photosystem II stabilization
N6G78_12685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N6G78_12690	COG2226	methyltransferase
N6G78_12695	COG0799	negative regulation of ribosome biogenesis
N6G78_12700	COG1713	HD superfamily hydrolase involved in NAD metabolism
N6G78_12705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N6G78_12710	COG1534	Rna-binding protein
N6G78_12715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N6G78_12720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N6G78_12725	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
N6G78_12735	COG2755	lipolytic protein G-D-S-L family
N6G78_12740	COG3409	Peptidoglycan-binding domain 1 protein
N6G78_12740	COG5632	N-Acetylmuramoyl-L-alanine amidase
N6G78_12745	COG0398	Pfam SNARE associated Golgi protein
N6G78_12750	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
N6G78_12760	COG3209	COG3209 Rhs family protein
N6G78_12780	COG3223	Belongs to the PsiE family
N6G78_12785	COG5002	protein histidine kinase activity
N6G78_12785	COG0642	Histidine kinase
N6G78_12790	COG0745	RESPONSE REGULATOR receiver
N6G78_12795	COG2311	Membrane
N6G78_12800	COG0454	-acetyltransferase
N6G78_12805	COG1733	regulation of RNA biosynthetic process
N6G78_12810	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_12845	COG4824	toxin secretion phage lysis holin
N6G78_12865	COG0563	adenylate kinase activity
N6G78_12890	COG2249	NAD(P)H dehydrogenase (quinone) activity
N6G78_12900	COG1846	Transcriptional regulator
N6G78_12905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N6G78_12915	COG0457	Tetratricopeptide repeat
N6G78_12920	COG5444	nuclease activity
N6G78_12945	COG0789	Transcriptional regulator
N6G78_12945	COG4978	Transcriptional regulator
N6G78_12950	COG2814	Major facilitator Superfamily
N6G78_12955	COG0456	acetyltransferase
N6G78_12960	COG1253	flavin adenine dinucleotide binding
N6G78_12970	COG0697	spore germination
N6G78_12975	COG0583	DNA-binding transcription factor activity
N6G78_12980	COG2072	flavoprotein involved in K transport
N6G78_12985	COG1230	cation diffusion facilitator family transporter
N6G78_12990	COG1942	4-Oxalocrotonate Tautomerase
N6G78_12995	COG0583	DNA-binding transcription factor activity
N6G78_13005	COG1114	Component of the transport system for branched-chain amino acids
N6G78_13010	COG1687	branched-chain amino acid
N6G78_13015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N6G78_13020	COG1522	sequence-specific DNA binding
N6G78_13030	COG2124	cytochrome p450
N6G78_13040	COG1335	isochorismatase
N6G78_13060	COG2318	DinB family
N6G78_13070	COG2070	2-Nitropropane dioxygenase
N6G78_13075	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N6G78_13095	COG3443	Belongs to the bacterial solute-binding protein 9 family
N6G78_13100	COG1595	DNA-templated transcription, initiation
N6G78_13105	COG0667	Aldo Keto reductase
N6G78_13110	COG3409	Peptidoglycan-binding domain 1 protein
N6G78_13115	COG5566	PFAM Mor transcription activator
N6G78_13120	COG0596	Alpha beta hydrolase
N6G78_13125	COG4991	sh3 domain protein
N6G78_13130	COG4991	sh3 domain protein
N6G78_13140	COG0346	lactoylglutathione lyase activity
N6G78_13150	COG5577	PFAM Coat F domain
N6G78_13155	COG1063	alcohol dehydrogenase
N6G78_13165	COG5577	PFAM Coat F domain
N6G78_13170	COG0789	Transcriptional regulator
N6G78_13180	COG1064	alcohol dehydrogenase
N6G78_13185	COG0693	protein deglycase activity
N6G78_13190	COG1621	beta-fructofuranosidase activity
N6G78_13200	COG3716	PTS system mannose fructose sorbose family IID component
N6G78_13205	COG3715	PTS system
N6G78_13210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N6G78_13215	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
N6G78_13220	COG3933	PFAM sigma-54 factor interaction domain-containing protein
N6G78_13220	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N6G78_13230	COG1113	amino acid transport
N6G78_13235	COG1280	lysine exporter protein (LysE YggA)
N6G78_13240	COG1378	Sugar-specific transcriptional regulator TrmB
N6G78_13245	COG1595	DNA-templated transcription, initiation
N6G78_13255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N6G78_13255	COG2755	lipolytic protein G-D-S-L family
N6G78_13265	COG2124	cytochrome p450
N6G78_13265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N6G78_13270	COG1309	transcriptional regulator
N6G78_13275	COG2226	methyltransferase
N6G78_13290	COG2116	formate transmembrane transporter activity
N6G78_13295	COG5609	conserved protein (DUF2294)
N6G78_13300	COG3383	formate dehydrogenase (NAD+) activity
N6G78_13305	COG2427	Protein of unknown function (DUF1641)
N6G78_13315	COG0626	cystathionine gamma-synthase activity
N6G78_13320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N6G78_13325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N6G78_13330	COG2226	methyltransferase
N6G78_13345	COG0768	penicillin binding
N6G78_13350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N6G78_13355	COG0572	uridine kinase
N6G78_13360	COG0826	peptidase U32
N6G78_13365	COG0826	peptidase U32
N6G78_13370	COG4122	O-methyltransferase activity
N6G78_13375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N6G78_13380	COG3906	Belongs to the UPF0473 family
N6G78_13385	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N6G78_13390	COG4472	Bacterial protein of unknown function (DUF965)
N6G78_13395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N6G78_13400	COG0628	permease
N6G78_13405	COG1126	abc transporter atp-binding protein
N6G78_13410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N6G78_13415	COG0765	amino acid transport
N6G78_13420	COG0765	amino acid transport
N6G78_13435	COG3881	PFAM PRC-barrel domain
N6G78_13440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N6G78_13445	COG0457	Tetratricopeptide repeat
N6G78_13450	COG0482	sulfurtransferase activity
N6G78_13455	COG1104	cysteine desulfurase activity
N6G78_13460	COG1959	2 iron, 2 sulfur cluster binding
N6G78_13465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N6G78_13470	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N6G78_13480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N6G78_13485	COG0124	histidyl-tRNA synthetase
N6G78_13495	COG0860	N-Acetylmuramoyl-L-alanine amidase
N6G78_13495	COG3103	Sh3 type 3 domain protein
N6G78_13495	COG4991	sh3 domain protein
N6G78_13500	COG1490	D-aminoacyl-tRNA deacylase activity
N6G78_13505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N6G78_13510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N6G78_13515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N6G78_13515	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
N6G78_13520	COG5416	Lipopolysaccharide assembly protein A domain
N6G78_13525	COG0490	domain, Protein
N6G78_13530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N6G78_13530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N6G78_13540	COG2244	polysaccharide biosynthetic process
N6G78_13545	COG2323	membrane
N6G78_13555	COG1862	Preprotein translocase
N6G78_13560	COG0343	queuine tRNA-ribosyltransferase activity
N6G78_13565	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N6G78_13575	COG2255	four-way junction helicase activity
N6G78_13580	COG0632	four-way junction helicase activity
N6G78_13590	COG2814	Major facilitator Superfamily
N6G78_13595	COG0673	inositol 2-dehydrogenase activity
N6G78_13600	COG2112	serine threonine protein kinase
N6G78_13620	COG1115	amino acid carrier protein
N6G78_13625	COG0217	transcriptional regulatory protein
N6G78_13635	COG1388	LysM domain
N6G78_13640	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N6G78_13645	COG0157	Belongs to the NadC ModD family
N6G78_13650	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N6G78_13655	COG1104	cysteine desulfurase activity
N6G78_13660	COG1827	regulation of RNA biosynthetic process
N6G78_13665	COG0077	Prephenate dehydratase
N6G78_13670	COG4492	Belongs to the UPF0735 family
N6G78_13675	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N6G78_13680	COG3290	protein histidine kinase activity
N6G78_13690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N6G78_13695	COG2868	ribosomal protein
N6G78_13700	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N6G78_13705	COG1994	Peptidase M50
N6G78_13710	COG0739	heme binding
N6G78_13715	COG2894	cell division
N6G78_13720	COG0850	regulation of cytokinetic process
N6G78_13725	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N6G78_13735	COG1077	Cell shape determining protein MreB Mrl
N6G78_13740	COG2003	Belongs to the UPF0758 family
N6G78_13745	COG0424	maF-like protein
N6G78_13755	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
N6G78_13760	COG0285	dihydrofolate synthase activity
N6G78_13765	COG0525	valine-tRNA ligase activity
N6G78_13775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N6G78_13780	COG1388	LysM domain
N6G78_13785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N6G78_13790	COG0113	porphobilinogen synthase activity
N6G78_13795	COG1587	Uroporphyrinogen-III synthase
N6G78_13800	COG0181	hydroxymethylbilane synthase activity
N6G78_13805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N6G78_13810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N6G78_13820	COG0218	Necessary for normal cell division and for the maintenance of normal septation
N6G78_13825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N6G78_13830	COG0470	DNA polymerase III
N6G78_13830	COG1067	ATP-dependent peptidase activity
N6G78_13835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N6G78_13840	COG0544	peptidyl-prolyl cis-trans isomerase activity
N6G78_13845	COG1477	protein flavinylation
N6G78_13845	COG0457	Tetratricopeptide repeat
N6G78_13850	COG0066	3-isopropylmalate dehydratase activity
N6G78_13855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N6G78_13860	COG0473	3-isopropylmalate dehydrogenase activity
N6G78_13865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N6G78_13870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N6G78_13875	COG0440	acetolactate synthase activity
N6G78_13880	COG0028	Belongs to the TPP enzyme family
N6G78_13890	COG0454	-acetyltransferase
N6G78_13895	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
N6G78_13905	COG0622	Phosphoesterase
N6G78_13910	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N6G78_13915	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N6G78_13920	COG5401	PFAM Sporulation and spore germination
N6G78_13925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N6G78_13930	COG1846	Transcriptional regulator
N6G78_13935	COG2197	response regulator
N6G78_13940	COG0824	Thioesterase
N6G78_13945	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N6G78_13950	COG1053	succinate dehydrogenase
N6G78_13955	COG2009	succinate dehydrogenase
N6G78_13960	COG1719	4-vinyl reductase, 4VR
N6G78_13965	COG0527	aspartate kinase activity
N6G78_13970	COG0322	excinuclease ABC activity
N6G78_13975	COG3118	belongs to the thioredoxin family
N6G78_13985	COG3534	alpha-L-arabinofuranosidase
N6G78_13990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N6G78_13995	COG2086	electron transfer activity
N6G78_14000	COG1024	Enoyl-CoA hydratase
N6G78_14005	COG1309	transcriptional regulator
N6G78_14010	COG0318	PFAM AMP-dependent synthetase and ligase
N6G78_14015	COG3766	membrane
N6G78_14020	COG1193	negative regulation of DNA recombination
N6G78_14025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N6G78_14025	COG1796	DNA polymerase
N6G78_14030	COG1286	toxin biosynthetic process
N6G78_14035	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
N6G78_14040	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N6G78_14045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N6G78_14045	COG0072	phenylalanine-tRNA ligase activity
N6G78_14050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N6G78_14060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N6G78_14070	COG3835	regulator
N6G78_14075	COG0277	FAD linked oxidase domain protein
N6G78_14080	COG0247	lactate metabolic process
N6G78_14085	COG0346	lactoylglutathione lyase activity
N6G78_14095	COG1966	Carbon starvation protein
N6G78_14100	COG3534	alpha-L-arabinofuranosidase
N6G78_14105	COG0395	ABC-type sugar transport system, permease component
N6G78_14110	COG1175	transmembrane transport
N6G78_14115	COG1653	transport
N6G78_14120	COG0371	Dehydrogenase
N6G78_14125	COG0647	UMP catabolic process
N6G78_14130	COG0235	Class ii aldolase
N6G78_14135	COG1069	ribulokinase activity
N6G78_14140	COG2160	L-arabinose isomerase activity
N6G78_14145	COG3507	Belongs to the glycosyl hydrolase 43 family
N6G78_14150	COG1363	Peptidase, m42
N6G78_14160	COG3326	Membrane
N6G78_14165	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N6G78_14170	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N6G78_14175	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N6G78_14185	COG1346	cytolysis
N6G78_14190	COG1380	Effector of murein hydrolase LrgA
N6G78_14195	COG3279	Response regulator of the LytR AlgR family
N6G78_14200	COG3275	phosphorelay sensor kinase activity
N6G78_14205	COG1011	Hydrolase
N6G78_14210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N6G78_14220	COG0398	Pfam SNARE associated Golgi protein
N6G78_14225	COG1484	DNA-dependent DNA replication
N6G78_14230	COG3611	Membrane attachment protein
N6G78_14235	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N6G78_14240	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
N6G78_14245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N6G78_14250	COG1733	regulation of RNA biosynthetic process
N6G78_14255	COG2814	Major facilitator Superfamily
N6G78_14260	COG0656	L-ascorbic acid biosynthetic process
N6G78_14265	COG0237	dephospho-CoA kinase activity
N6G78_14275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N6G78_14280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N6G78_14280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N6G78_14285	COG5002	protein histidine kinase activity
N6G78_14290	COG0745	RESPONSE REGULATOR receiver
N6G78_14295	COG0039	L-malate dehydrogenase activity
N6G78_14300	COG0538	isocitrate dehydrogenase activity
N6G78_14305	COG0372	Belongs to the citrate synthase family
N6G78_14310	COG2707	UPF0756 membrane protein
N6G78_14315	COG0628	permease
N6G78_14320	COG3030	protein affecting phage T7 exclusion by the F plasmid
N6G78_14325	COG0469	pyruvate kinase activity
N6G78_14330	COG0205	6-phosphofructokinase activity
N6G78_14335	COG0825	malonyl-CoA metabolic process
N6G78_14340	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N6G78_14345	COG0281	malic enzyme
N6G78_14350	COG0587	DNA-directed DNA polymerase activity
N6G78_14370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N6G78_14380	COG4109	DRTGG domain
N6G78_14385	COG0730	response to heat
N6G78_14390	COG1473	amidohydrolase
N6G78_14395	COG0196	riboflavin kinase activity
N6G78_14400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N6G78_14410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N6G78_14415	COG1126	abc transporter atp-binding protein
N6G78_14420	COG0765	amino acid transport
N6G78_14425	COG0765	amino acid transport
N6G78_14430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N6G78_14435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N6G78_14440	COG0454	-acetyltransferase
N6G78_14445	COG0583	DNA-binding transcription factor activity
N6G78_14450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N6G78_14455	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_14465	COG0165	Argininosuccinate lyase
N6G78_14470	COG0137	argininosuccinate synthase activity
N6G78_14475	COG0521	Mo-molybdopterin cofactor biosynthetic process
N6G78_14480	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N6G78_14490	COG0827	DNA restriction-modification system
N6G78_14495	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
N6G78_14500	COG3874	Sporulation protein YtfJ
N6G78_14510	COG1714	RDD family
N6G78_14515	COG0616	signal peptide processing
N6G78_14520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N6G78_14525	COG1574	metal-dependent hydrolase with the TIM-barrel fold
N6G78_14530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N6G78_14540	COG0301	tRNA thio-modification
N6G78_14545	COG1104	cysteine desulfurase activity
N6G78_14550	COG1114	Component of the transport system for branched-chain amino acids
N6G78_14555	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
N6G78_14560	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N6G78_14565	COG1309	transcriptional regulator
N6G78_14570	COG1956	GAF domain-containing protein
N6G78_14575	COG2203	Gaf domain
N6G78_14575	COG2199	diguanylate cyclase activity
N6G78_14580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N6G78_14590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N6G78_14595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N6G78_14600	COG0454	-acetyltransferase
N6G78_14605	COG0517	IMP dehydrogenase activity
N6G78_14610	COG0123	including yeast histone deacetylase and acetoin utilization protein
N6G78_14615	COG1360	Flagellar Motor Protein
N6G78_14620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N6G78_14625	COG1609	Transcriptional regulator
N6G78_14630	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
N6G78_14630	COG1605	Chorismate mutase
N6G78_14635	COG3118	belongs to the thioredoxin family
N6G78_14640	COG4980	gas vesicle protein
N6G78_14645	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N6G78_14650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N6G78_14655	COG1674	ftsk spoiiie
N6G78_14660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N6G78_14665	COG4848	Belongs to the UPF0354 family
N6G78_14670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N6G78_14685	COG1363	Peptidase, m42
N6G78_14690	COG5584	Small secreted protein
N6G78_14695	COG0281	malic enzyme
N6G78_14700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N6G78_14705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N6G78_14715	COG0510	thiamine kinase activity
N6G78_14720	COG1523	belongs to the glycosyl hydrolase 13 family
N6G78_14725	COG1597	lipid kinase activity
N6G78_14735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N6G78_14740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N6G78_14745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N6G78_14750	COG2252	PERMEase
N6G78_14755	COG4473	ABC transporter
N6G78_14760	COG1131	(ABC) transporter
N6G78_14765	COG1349	DNA-binding transcription factor activity
N6G78_14770	COG1187	pseudouridine synthase activity
N6G78_14775	COG2244	polysaccharide biosynthetic process
N6G78_14780	COG2081	HI0933 family
N6G78_14785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N6G78_14795	COG5578	integral membrane protein
N6G78_14800	COG0673	inositol 2-dehydrogenase activity
N6G78_14805	COG1653	transport
N6G78_14810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N6G78_14815	COG4209	transmembrane transport
N6G78_14820	COG2207	Transcriptional regulator
N6G78_14825	COG1653	transport
N6G78_14830	COG0395	ABC-type sugar transport system, permease component
N6G78_14835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N6G78_14840	COG2124	cytochrome p450
N6G78_14845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N6G78_14855	COG0156	8-amino-7-oxononanoate synthase activity
N6G78_14860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N6G78_14870	COG1073	alpha beta
N6G78_14875	COG1609	Transcriptional regulator
N6G78_14880	COG1653	transport
N6G78_14885	COG1175	transmembrane transport
N6G78_14890	COG0395	ABC-type sugar transport system, permease component
N6G78_14895	COG1486	melibiose metabolic process
N6G78_14900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N6G78_14905	COG0495	leucyl-tRNA aminoacylation
N6G78_14915	COG2202	Pas domain
N6G78_14915	COG1366	Belongs to the anti-sigma-factor antagonist family
N6G78_14920	COG2814	Major facilitator Superfamily
N6G78_14925	COG2433	Pfam Transposase IS66
N6G78_14930	COG0577	efflux transmembrane transporter activity
N6G78_14935	COG1136	(ABC) transporter
N6G78_14940	COG2205	protein histidine kinase activity
N6G78_14945	COG0745	RESPONSE REGULATOR receiver
N6G78_14950	COG0577	efflux transmembrane transporter activity
N6G78_14955	COG1136	(ABC) transporter
N6G78_14970	COG1131	(ABC) transporter
N6G78_14975	COG1725	Transcriptional regulator
N6G78_14990	COG1242	4 iron, 4 sulfur cluster binding
N6G78_14995	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
N6G78_15005	COG2267	carboxylic ester hydrolase activity
N6G78_15010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N6G78_15015	COG1113	amino acid transport
N6G78_15020	COG0367	asparagine synthase
N6G78_15025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N6G78_15030	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N6G78_15040	COG1506	peptidase
N6G78_15045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N6G78_15050	COG1116	anion transmembrane transporter activity
N6G78_15055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N6G78_15060	COG0494	nUDIX hydrolase
N6G78_15065	COG4824	toxin secretion phage lysis holin
N6G78_15070	COG0783	Belongs to the Dps family
N6G78_15085	COG1854	S-ribosylhomocysteine lyase activity
N6G78_15090	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N6G78_15095	COG0288	reversible hydration of carbon dioxide
N6G78_15100	COG0254	rRNA binding
N6G78_15105	COG1271	oxidase subunit
N6G78_15110	COG1294	oxidase, subunit
N6G78_15120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N6G78_15125	COG1321	iron dependent repressor
N6G78_15125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N6G78_15130	COG1121	(ABC) transporter
N6G78_15135	COG0803	Belongs to the bacterial solute-binding protein 9 family
N6G78_15140	COG4948	Mandelate Racemase Muconate Lactonizing
N6G78_15145	COG0318	PFAM AMP-dependent synthetase and ligase
N6G78_15150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
N6G78_15155	COG0596	Alpha beta hydrolase
N6G78_15160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N6G78_15165	COG1169	isochorismate synthase
N6G78_15170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N6G78_15175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N6G78_15180	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N6G78_15185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N6G78_15190	COG0438	transferase activity, transferring glycosyl groups
N6G78_15200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N6G78_15205	COG0438	transferase activity, transferring glycosyl groups
N6G78_15210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N6G78_15215	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
N6G78_15220	COG0058	SHG alpha-glucan phosphorylase activity
N6G78_15225	COG0297	glycogen (starch) synthase activity
N6G78_15230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N6G78_15235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N6G78_15240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N6G78_15365	COG3859	Proton-coupled thiamine transporter YuaJ
N6G78_15375	COG2268	Band 7 protein
N6G78_15380	COG1585	Membrane protein implicated in regulation of membrane protease activity
N6G78_15385	COG2318	DinB family
N6G78_15395	COG1454	alcohol dehydrogenase
N6G78_15400	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_15405	COG1510	regulation of RNA biosynthetic process
N6G78_15415	COG0569	domain protein
N6G78_15420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N6G78_15425	COG4682	membrane
N6G78_15430	COG1705	Flagellar rod assembly protein muramidase FlgJ
N6G78_15435	COG0477	Major facilitator Superfamily
N6G78_15440	COG5553	Cysteine dioxygenase type I
N6G78_15450	COG1968	undecaprenyl-diphosphatase activity
N6G78_15455	COG0628	permease
N6G78_15460	COG0673	inositol 2-dehydrogenase activity
N6G78_15465	COG4806	L-rhamnose isomerase
N6G78_15470	COG3254	rhamnose metabolic process
N6G78_15475	COG1070	Carbohydrate kinase
N6G78_15480	COG1349	DNA-binding transcription factor activity
N6G78_15485	COG3347	Dehydrogenase
N6G78_15485	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_15490	COG0840	transmembrane signaling receptor activity
N6G78_15495	COG0840	transmembrane signaling receptor activity
N6G78_15500	COG0840	transmembrane signaling receptor activity
N6G78_15505	COG0840	transmembrane signaling receptor activity
N6G78_15525	COG0432	Pfam Uncharacterised protein family UPF0047
N6G78_15530	COG0366	Alpha amylase catalytic
N6G78_15535	COG1253	flavin adenine dinucleotide binding
N6G78_15540	COG2738	Putative neutral zinc metallopeptidase
N6G78_15555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N6G78_15570	COG0166	Belongs to the GPI family
N6G78_15575	COG1979	alcohol dehydrogenase
N6G78_15580	COG1979	alcohol dehydrogenase
N6G78_15585	COG2155	Conserved Protein
N6G78_15590	COG1098	S1 RNA binding domain
N6G78_15595	COG0436	Aminotransferase
N6G78_15600	COG1522	sequence-specific DNA binding
N6G78_15605	COG2267	carboxylic ester hydrolase activity
N6G78_15615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
N6G78_15620	COG2205	protein histidine kinase activity
N6G78_15630	COG5018	Exonuclease
N6G78_15640	COG2814	Major facilitator Superfamily
N6G78_15645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N6G78_15650	COG3011	Protein conserved in bacteria
N6G78_15660	COG3290	protein histidine kinase activity
N6G78_15665	COG4565	transcriptional regulatory protein
N6G78_15670	COG1744	ABC transporter substrate-binding protein PnrA-like
N6G78_15675	COG3845	ABC transporter
N6G78_15680	COG4603	Belongs to the binding-protein-dependent transport system permease family
N6G78_15685	COG1079	Belongs to the binding-protein-dependent transport system permease family
N6G78_15690	COG3493	citrate carrier protein
N6G78_15700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N6G78_15700	COG2111	Na H antiporter
N6G78_15705	COG2111	Na H antiporter
N6G78_15710	COG1006	Multisubunit Na H antiporter MnhC subunit
N6G78_15715	COG0651	ATP synthesis coupled electron transport
N6G78_15720	COG1863	multisubunit Na H antiporter MnhE subunit
N6G78_15725	COG2212	antiporter activity
N6G78_15730	COG1320	monovalent cation:proton antiporter activity
N6G78_15735	COG2050	protein possibly involved in aromatic compounds catabolism
N6G78_15745	COG4585	Histidine kinase
N6G78_15755	COG0142	geranyltranstransferase activity
N6G78_15775	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N6G78_15780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N6G78_15785	COG1335	isochorismatase
N6G78_15790	COG5506	Protein of unknown function (DUF1694)
N6G78_15805	COG0628	permease
N6G78_15820	COG1418	mRNA catabolic process
N6G78_15825	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_15835	COG1511	domain protein
N6G78_15840	COG0433	COG0433 Predicted ATPase
N6G78_15840	COG1674	ftsk spoiiie
N6G78_15845	COG4499	WXG100 protein secretion system (Wss), protein YukC
N6G78_15850	COG5417	Belongs to the EsaB family
N6G78_15855	COG4842	Belongs to the WXG100 family
N6G78_15860	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N6G78_15860	COG2508	Transcriptional regulator
N6G78_15865	COG0686	Belongs to the AlaDH PNT family
N6G78_15870	COG5634	Uncharacterized conserved protein (DUF2278)
N6G78_15875	COG3251	PFAM MbtH domain protein
N6G78_15880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_15885	COG1535	isochorismatase
N6G78_15885	COG3433	isochorismatase activity
N6G78_15890	COG1021	2,3-dihydroxybenzoate-AMP ligase
N6G78_15895	COG1169	isochorismate synthase
N6G78_15900	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_15905	COG2819	hydrolase of the alpha beta superfamily
N6G78_15910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N6G78_15915	COG1268	BioY protein
N6G78_15920	COG2056	Na+-H+ antiporter family
N6G78_15925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N6G78_15930	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
N6G78_15935	COG3584	3D domain protein
N6G78_15950	COG1252	NADH dehydrogenase
N6G78_15955	COG0492	ferredoxin-NADP+ reductase activity
N6G78_15965	COG0516	GMP reductase activity
N6G78_15970	COG2808	Putative FMN-binding domain
N6G78_15975	COG0456	acetyltransferase
N6G78_15980	COG0316	Belongs to the HesB IscA family
N6G78_15985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N6G78_15990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N6G78_15995	COG4844	belongs to the
N6G78_16000	COG1252	NADH dehydrogenase
N6G78_16005	COG4837	Protein of unknown function (DUF1462)
N6G78_16010	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N6G78_16015	COG4946	Tricorn protease homolog
N6G78_16015	COG1506	peptidase
N6G78_16015	COG0823	Involved in the tonB-independent uptake of proteins
N6G78_16020	COG0083	homoserine kinase activity
N6G78_16025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N6G78_16030	COG0460	homoserine dehydrogenase
N6G78_16035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N6G78_16040	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N6G78_16045	COG0647	UMP catabolic process
N6G78_16050	COG2445	Protein of unknown function DUF86
N6G78_16055	COG4470	Protein conserved in bacteria
N6G78_16065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N6G78_16070	COG0739	heme binding
N6G78_16080	COG3377	Domain of unknown function (DUF1805)
N6G78_16085	COG0737	Belongs to the 5'-nucleotidase family
N6G78_16090	COG0730	response to heat
N6G78_16095	COG1801	Protein of unknown function DUF72
N6G78_16105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N6G78_16110	COG2508	Transcriptional regulator
N6G78_16115	COG2233	PERMEase
N6G78_16120	COG2233	PERMEase
N6G78_16125	COG3648	Uricase
N6G78_16125	COG3195	allantoin biosynthetic process
N6G78_16130	COG2351	hydroxyisourate hydrolase activity
N6G78_16140	COG2080	2 iron, 2 sulfur cluster binding
N6G78_16145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N6G78_16150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
N6G78_16155	COG2068	MobA-Related Protein
N6G78_16160	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N6G78_16165	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N6G78_16170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N6G78_16180	COG2356	endonuclease I
N6G78_16185	COG3842	ATPase activity
N6G78_16190	COG2188	Transcriptional regulator
N6G78_16195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N6G78_16200	COG0395	ABC-type sugar transport system, permease component
N6G78_16205	COG1175	transmembrane transport
N6G78_16210	COG1653	transport
N6G78_16215	COG2222	sugar isomerase
N6G78_16220	COG0322	excinuclease ABC activity
N6G78_16225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N6G78_16240	COG0346	lactoylglutathione lyase activity
N6G78_16245	COG0640	Transcriptional regulator
N6G78_16250	COG0719	Fe-S assembly protein
N6G78_16255	COG0822	iron-sulfur transferase activity
N6G78_16260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N6G78_16265	COG0719	Fe-S assembly protein
N6G78_16270	COG0396	ATPase activity
N6G78_16280	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N6G78_16285	COG1464	Belongs to the NlpA lipoprotein family
N6G78_16290	COG2011	ABC-type metal ion transport system permease component
N6G78_16295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N6G78_16310	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N6G78_16320	COG0509	glycine decarboxylation via glycine cleavage system
N6G78_16325	COG1393	Belongs to the ArsC family
N6G78_16330	COG1960	acyl-CoA dehydrogenase activity
N6G78_16335	COG0183	Belongs to the thiolase family
N6G78_16340	COG1024	Enoyl-CoA hydratase
N6G78_16340	COG1250	3-hydroxyacyl-CoA dehydrogenase
N6G78_16350	COG0506	proline dehydrogenase activity
N6G78_16360	COG5577	PFAM Coat F domain
N6G78_16365	COG1846	Transcriptional regulator
N6G78_16370	COG0477	Major facilitator Superfamily
N6G78_16375	COG1942	4-Oxalocrotonate Tautomerase
N6G78_16380	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_16385	COG0583	DNA-binding transcription factor activity
N6G78_16395	COG1120	ATPase activity
N6G78_16410	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_16415	COG0783	Belongs to the Dps family
N6G78_16420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N6G78_16425	COG0745	RESPONSE REGULATOR receiver
N6G78_16430	COG2770	Histidine kinase
N6G78_16430	COG2205	protein histidine kinase activity
N6G78_16440	COG1309	transcriptional regulator
N6G78_16445	COG0114	fumarate hydratase activity
N6G78_16455	COG0697	spore germination
N6G78_16460	COG0814	amino acid
N6G78_16470	COG2197	response regulator
N6G78_16475	COG4585	Histidine kinase
N6G78_16480	COG4758	membrane
N6G78_16485	COG3595	metallopeptidase activity
N6G78_16490	COG1842	Phage shock protein A
N6G78_16495	COG4758	membrane
N6G78_16500	COG2814	Major facilitator Superfamily
N6G78_16505	COG2096	Adenosyltransferase
N6G78_16510	COG1120	ATPase activity
N6G78_16515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N6G78_16520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N6G78_16525	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_16530	COG3386	PFAM SMP-30 Gluconolaconase
N6G78_16535	COG2205	protein histidine kinase activity
N6G78_16540	COG0745	RESPONSE REGULATOR receiver
N6G78_16550	COG1191	sigma factor activity
N6G78_16560	COG2140	Oxalate decarboxylase
N6G78_16570	COG0577	efflux transmembrane transporter activity
N6G78_16575	COG1136	(ABC) transporter
N6G78_16580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N6G78_16585	COG1120	ATPase activity
N6G78_16590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N6G78_16595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N6G78_16600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N6G78_16605	COG0531	amino acid
N6G78_16615	COG1988	membrane-bound metal-dependent
N6G78_16620	COG1368	sulfuric ester hydrolase activity
N6G78_16625	COG1910	domain protein
N6G78_16630	COG0725	ABC transporter, periplasmic molybdate-binding protein
N6G78_16635	COG4149	molybdate abc transporter
N6G78_16640	COG0656	L-ascorbic acid biosynthetic process
N6G78_16650	COG0025	NhaP-type Na H and K H
N6G78_16655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N6G78_16660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N6G78_16665	COG3973	AAA domain
N6G78_16675	COG2860	membrane
N6G78_16680	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
N6G78_16685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N6G78_16690	COG2217	Heavy metal translocating P-type atpase
N6G78_16695	COG2217	Heavy metal translocating P-type atpase
N6G78_16700	COG2608	mercury ion transmembrane transporter activity
N6G78_16705	COG1937	Protein conserved in bacteria
N6G78_16710	COG0673	inositol 2-dehydrogenase activity
N6G78_16715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N6G78_16720	COG1289	transmembrane transporter activity
N6G78_16730	COG2076	Multidrug Resistance protein
N6G78_16735	COG1309	transcriptional regulator
N6G78_16740	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_16750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N6G78_16755	COG0557	exoribonuclease II activity
N6G78_16760	COG1647	Serine aminopeptidase, S33
N6G78_16765	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N6G78_16770	COG0596	Alpha beta hydrolase
N6G78_16775	COG1476	TRANSCRIPTIONal
N6G78_16780	COG1396	sequence-specific DNA binding
N6G78_16785	COG1396	sequence-specific DNA binding
N6G78_16790	COG1733	regulation of RNA biosynthetic process
N6G78_16815	COG1174	glycine betaine transport
N6G78_16820	COG1732	Glycine betaine
N6G78_16825	COG1174	glycine betaine transport
N6G78_16830	COG0517	IMP dehydrogenase activity
N6G78_16830	COG1125	glycine betaine transport
N6G78_16835	COG1510	regulation of RNA biosynthetic process
N6G78_16840	COG1174	glycine betaine transport
N6G78_16845	COG1732	Glycine betaine
N6G78_16850	COG1174	glycine betaine transport
N6G78_16855	COG0517	IMP dehydrogenase activity
N6G78_16855	COG1125	glycine betaine transport
N6G78_16860	COG1510	regulation of RNA biosynthetic process
N6G78_16865	COG2095	MarC family integral membrane protein
N6G78_16875	COG3064	Membrane
N6G78_16880	COG4640	response to antibiotic
N6G78_16885	COG0456	acetyltransferase
N6G78_16900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N6G78_16920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N6G78_16925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N6G78_16935	COG2234	aminopeptidase activity
N6G78_16940	COG0148	phosphopyruvate hydratase activity
N6G78_16945	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N6G78_16950	COG0149	triose-phosphate isomerase activity
N6G78_16955	COG0126	phosphoglycerate kinase activity
N6G78_16960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N6G78_16965	COG2390	Transcriptional regulator
N6G78_16970	COG2814	Major facilitator Superfamily
N6G78_16975	COG1609	Transcriptional regulator
N6G78_16980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N6G78_16985	COG0583	DNA-binding transcription factor activity
N6G78_16990	COG0697	spore germination
N6G78_16995	COG1113	amino acid transport
N6G78_17000	COG3858	chitin binding
N6G78_17005	COG1556	Lactate utilization protein
N6G78_17010	COG1139	Iron-sulfur cluster binding protein
N6G78_17015	COG0247	lactate metabolic process
N6G78_17020	COG2197	response regulator
N6G78_17025	COG4585	Histidine kinase
N6G78_17030	COG0842	Transport permease protein
N6G78_17035	COG1131	(ABC) transporter
N6G78_17040	COG0596	Alpha beta hydrolase
N6G78_17045	COG2208	phosphoserine phosphatase activity
N6G78_17050	COG3867	Arabinogalactan endo-beta-1,4-galactanase
N6G78_17055	COG1874	Beta-galactosidase
N6G78_17060	COG3833	ABC-type maltose transport systems, permease component
N6G78_17065	COG1175	transmembrane transport
N6G78_17070	COG2182	Extracellular solute-binding protein
N6G78_17075	COG1609	Transcriptional regulator
N6G78_17080	COG2186	Transcriptional regulator
N6G78_17085	COG1620	l-lactate permease
N6G78_17090	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N6G78_17100	COG5039	Polysaccharide pyruvyl transferase
N6G78_17105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N6G78_17110	COG0110	maltose O-acetyltransferase activity
N6G78_17115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N6G78_17120	COG2244	polysaccharide biosynthetic process
N6G78_17125	COG1216	Glycosyl transferase, family 2
N6G78_17130	COG5039	Polysaccharide pyruvyl transferase
N6G78_17135	COG1216	Glycosyl transferase, family 2
N6G78_17145	COG0438	transferase activity, transferring glycosyl groups
N6G78_17150	COG1215	transferase activity, transferring glycosyl groups
N6G78_17155	COG0438	transferase activity, transferring glycosyl groups
N6G78_17160	COG1086	Polysaccharide biosynthesis protein
N6G78_17165	COG0489	protein tyrosine kinase activity
N6G78_17170	COG3944	biosynthesis protein
N6G78_17175	COG1396	sequence-specific DNA binding
N6G78_17180	COG2272	Belongs to the type-B carboxylesterase lipase family
N6G78_17190	COG3479	Phenolic acid decarboxylase
N6G78_17200	COG1794	racemase activity, acting on amino acids and derivatives
N6G78_17215	COG1621	beta-fructofuranosidase activity
N6G78_17220	COG1621	beta-fructofuranosidase activity
N6G78_17225	COG0531	amino acid
N6G78_17230	COG1309	transcriptional regulator
N6G78_17235	COG2076	Multidrug Resistance protein
N6G78_17240	COG2076	Multidrug Resistance protein
N6G78_17275	COG0740	serine-type endopeptidase activity
N6G78_17280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N6G78_17285	COG0366	Alpha amylase catalytic
N6G78_17290	COG1554	hydrolase, family 65, central catalytic
N6G78_17295	COG5521	maltodextrose utilization protein MalA
N6G78_17300	COG3833	ABC-type maltose transport systems, permease component
N6G78_17305	COG1175	transmembrane transport
N6G78_17310	COG2182	Extracellular solute-binding protein
N6G78_17315	COG0366	Alpha amylase catalytic
N6G78_17320	COG1609	Transcriptional regulator
N6G78_17325	COG1611	Belongs to the LOG family
N6G78_17330	COG1694	Mazg nucleotide pyrophosphohydrolase
N6G78_17335	COG0659	secondary active sulfate transmembrane transporter activity
N6G78_17340	COG0288	reversible hydration of carbon dioxide
N6G78_17345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N6G78_17350	COG0577	efflux transmembrane transporter activity
N6G78_17355	COG1136	(ABC) transporter
N6G78_17360	COG5002	protein histidine kinase activity
N6G78_17365	COG0745	RESPONSE REGULATOR receiver
N6G78_17375	COG2162	N-hydroxyarylamine O-acetyltransferase activity
N6G78_17380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N6G78_17385	COG1481	regulation of sporulation
N6G78_17390	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N6G78_17395	COG1660	Displays ATPase and GTPase activities
N6G78_17400	COG1051	belongs to the nudix hydrolase family
N6G78_17405	COG0492	ferredoxin-NADP+ reductase activity
N6G78_17410	COG3883	PFAM NLP P60 protein
N6G78_17410	COG0791	NLP P60 protein
N6G78_17415	COG0457	Tetratricopeptide repeat
N6G78_17420	COG1132	(ABC) transporter
N6G78_17440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N6G78_17440	COG0140	phosphoribosyl-ATP diphosphatase activity
N6G78_17445	COG0107	imidazoleglycerol-phosphate synthase activity
N6G78_17450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N6G78_17455	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N6G78_17460	COG0131	Imidazoleglycerol-phosphate dehydratase
N6G78_17465	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N6G78_17470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N6G78_17475	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
N6G78_17480	COG4990	cell redox homeostasis
N6G78_17485	COG5297	Belongs to the glycosyl hydrolase family 6
N6G78_17490	COG0110	maltose O-acetyltransferase activity
N6G78_17495	COG0546	phosphoglycolate phosphatase activity
N6G78_17500	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
N6G78_17505	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N6G78_17510	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
N6G78_17515	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N6G78_17520	COG0363	glucosamine-6-phosphate deaminase activity
N6G78_17525	COG2188	Transcriptional regulator
N6G78_17530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N6G78_17535	COG1950	PFAM Membrane protein of
N6G78_17540	COG1983	PspC domain protein
N6G78_17545	COG3595	metallopeptidase activity
N6G78_17560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N6G78_17565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N6G78_17570	COG0556	nucleotide-excision repair
N6G78_17575	COG4897	Protein conserved in bacteria
N6G78_17580	COG0574	Belongs to the PEP-utilizing enzyme family
N6G78_17580	COG3848	Pyruvate phosphate dikinase
N6G78_17585	COG1309	transcriptional regulator
N6G78_17590	COG2814	Major facilitator Superfamily
N6G78_17595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N6G78_17605	COG3409	Peptidoglycan-binding domain 1 protein
N6G78_17605	COG0793	Belongs to the peptidase S41A family
N6G78_17610	COG2177	Part of the ABC transporter FtsEX involved in
N6G78_17615	COG2884	Cell division ATP-binding protein ftsE
N6G78_17620	COG2010	Cytochrome c
N6G78_17625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N6G78_17635	COG0653	protein targeting
N6G78_17640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N6G78_17655	COG1516	flagellar protein fliS
N6G78_17660	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N6G78_17665	COG1334	flagellar protein FlaG
N6G78_17670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N6G78_17675	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N6G78_17680	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
N6G78_17690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N6G78_17695	COG4786	Flagellar basal body rod
N6G78_17695	COG1256	bacterial-type flagellum assembly
N6G78_17700	COG3418	PFAM FlgN family protein
N6G78_17705	COG2747	anti-sigma28 factor FlgM
N6G78_17715	COG1040	competence protein
N6G78_17725	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
N6G78_17730	COG1307	EDD domain protein, DegV family
N6G78_17735	COG2197	response regulator
N6G78_17740	COG4585	Histidine kinase
N6G78_17745	COG1739	Uncharacterized protein family UPF0029
N6G78_17750	COG1316	TRANSCRIPTIONal
N6G78_17755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N6G78_17760	COG0438	transferase activity, transferring glycosyl groups
N6G78_17765	COG1215	transferase activity, transferring glycosyl groups
N6G78_17770	COG3206	protein involved in exopolysaccharide biosynthesis
N6G78_17775	COG3307	-O-antigen
N6G78_17780	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N6G78_17785	COG0297	glycogen (starch) synthase activity
N6G78_17785	COG0438	transferase activity, transferring glycosyl groups
N6G78_17790	COG2244	polysaccharide biosynthetic process
N6G78_17805	COG0860	N-Acetylmuramoyl-L-alanine amidase
N6G78_17805	COG2247	cell wall binding repeat
N6G78_17810	COG2385	sporulation resulting in formation of a cellular spore
N6G78_17810	COG2247	cell wall binding repeat
N6G78_17820	COG1316	TRANSCRIPTIONal
N6G78_17825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N6G78_17845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N6G78_17850	COG1134	teichoic acid transport
N6G78_17855	COG1682	transport, permease protein
N6G78_17875	COG0463	Glycosyl transferase, family 2
N6G78_17920	COG4193	domain, Protein
N6G78_17925	COG1482	cell wall glycoprotein biosynthetic process
N6G78_17930	COG0697	spore germination
N6G78_17935	COG0814	amino acid
N6G78_17945	COG2814	Major facilitator Superfamily
N6G78_17950	COG1316	TRANSCRIPTIONal
N6G78_17955	COG0561	phosphatase activity
N6G78_17960	COG0791	NLP P60 protein
N6G78_17970	COG2843	Capsule synthesis protein
N6G78_17980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N6G78_17985	COG1609	Transcriptional regulator
N6G78_17990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N6G78_17995	COG1869	D-ribose catabolic process
N6G78_18000	COG1129	ABC transporter
N6G78_18005	COG1172	Belongs to the binding-protein-dependent transport system permease family
N6G78_18010	COG1879	ABC-type sugar transport system periplasmic component
N6G78_18015	COG3103	Sh3 type 3 domain protein
N6G78_18025	COG2249	NAD(P)H dehydrogenase (quinone) activity
N6G78_18030	COG3527	Alpha-acetolactate decarboxylase
N6G78_18035	COG0028	Belongs to the TPP enzyme family
N6G78_18040	COG0583	DNA-binding transcription factor activity
N6G78_18045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N6G78_18060	COG5337	Spore coat protein CotH
N6G78_18070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N6G78_18080	COG0405	Gamma-glutamyltransferase
N6G78_18085	COG1522	sequence-specific DNA binding
N6G78_18090	COG2059	Chromate
N6G78_18095	COG2059	Chromate
N6G78_18140	COG3878	Protein conserved in bacteria
N6G78_18145	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N6G78_18150	COG4464	protein tyrosine phosphatase activity
N6G78_18155	COG0489	protein tyrosine kinase activity
N6G78_18160	COG3944	biosynthesis protein
N6G78_18170	COG4715	Zinc finger, swim domain protein
N6G78_18175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N6G78_18180	COG0561	phosphatase activity
N6G78_18185	COG1349	DNA-binding transcription factor activity
N6G78_18190	COG0629	single-stranded DNA binding
N6G78_18205	COG3764	Sortase (surface protein transpeptidase)
N6G78_18215	COG3279	Response regulator of the LytR AlgR family
N6G78_18225	COG0745	RESPONSE REGULATOR receiver
N6G78_18225	COG2972	Histidine kinase
N6G78_18230	COG1970	mechanosensitive ion channel activity
N6G78_18235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N6G78_18240	COG0457	Tetratricopeptide repeat
N6G78_18245	COG4786	Flagellar basal body rod
N6G78_18250	COG4786	Flagellar basal body rod
N6G78_18255	COG1077	Cell shape determining protein MreB Mrl
N6G78_18260	COG1609	Transcriptional regulator
N6G78_18270	COG1846	Transcriptional regulator
N6G78_18275	COG2814	Major facilitator Superfamily
N6G78_18280	COG3420	alginic acid biosynthetic process
N6G78_18285	COG1953	Uracil, thiamine, allantoin
N6G78_18290	COG0477	Major facilitator Superfamily
N6G78_18295	COG1335	isochorismatase
N6G78_18305	COG0004	ammonium transporteR
N6G78_18310	COG0347	Belongs to the P(II) protein family
N6G78_18315	COG0671	phosphoesterase, PA-phosphatase related
N6G78_18325	COG0739	heme binding
N6G78_18330	COG1247	-acetyltransferase
N6G78_18340	COG2089	acid synthase
N6G78_18350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N6G78_18355	COG0789	Transcriptional regulator
N6G78_18365	COG2910	NAD(P)H-binding
N6G78_18370	COG1959	2 iron, 2 sulfur cluster binding
N6G78_18375	COG0804	urea catabolic process
N6G78_18380	COG0832	Belongs to the urease beta subunit family
N6G78_18385	COG0831	urea catabolic process
N6G78_18400	COG3237	CsbD-like
N6G78_18405	COG1994	Peptidase M50
N6G78_18410	COG0457	Tetratricopeptide repeat
N6G78_18415	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N6G78_18420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N6G78_18430	COG2304	oxidoreductase activity
N6G78_18440	COG2304	oxidoreductase activity
N6G78_18445	COG2385	sporulation resulting in formation of a cellular spore
N6G78_18450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N6G78_18460	COG4836	Membrane
N6G78_18470	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N6G78_18475	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N6G78_18480	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N6G78_18485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N6G78_18490	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N6G78_18495	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N6G78_18505	COG0356	it plays a direct role in the translocation of protons across the membrane
N6G78_18515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N6G78_18520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N6G78_18525	COG4475	Protein of unknown function (DUF436)
N6G78_18530	COG0698	ribose 5-phosphate isomerase
N6G78_18535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N6G78_18540	COG1971	Probably functions as a manganese efflux pump
N6G78_18545	COG0009	L-threonylcarbamoyladenylate synthase
N6G78_18550	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N6G78_18570	COG2890	protein-(glutamine-N5) methyltransferase activity
N6G78_18575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N6G78_18580	COG0346	lactoylglutathione lyase activity
N6G78_18585	COG0789	Transcriptional regulator
N6G78_18590	COG0679	Auxin Efflux Carrier
N6G78_18595	COG0281	malic enzyme
N6G78_18600	COG1435	thymidine kinase activity
N6G78_18610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N6G78_18620	COG1494	fructose-1,6-bisphosphatase
N6G78_18625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N6G78_18635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N6G78_18640	COG0191	fructose-bisphosphate aldolase activity
N6G78_18645	COG2204	response regulator
N6G78_18650	COG4821	SIS domain
N6G78_18655	COG0504	CTP synthase activity
N6G78_18660	COG3343	RNA polymerase activity
N6G78_18665	COG1960	acyl-CoA dehydrogenase activity
N6G78_18670	COG0247	lactate metabolic process
N6G78_18670	COG2181	nitrate reductase activity
N6G78_18675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N6G78_18680	COG4294	response to UV
N6G78_18690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N6G78_18695	COG1132	(ABC) transporter
N6G78_18700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N6G78_18710	COG2181	nitrate reductase activity
N6G78_18715	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
N6G78_18720	COG1140	nitrate reductase beta subunit
N6G78_18725	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
N6G78_18730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N6G78_18740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N6G78_18745	COG2223	nitrite transmembrane transporter activity
N6G78_18750	COG0018	arginyl-trna synthetase
N6G78_18755	COG4506	Protein conserved in bacteria
N6G78_18770	COG0535	radical SAM domain protein
N6G78_18780	COG1131	(ABC) transporter
N6G78_18785	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N6G78_18790	COG0612	Peptidase, M16
N6G78_18795	COG0612	Peptidase, M16
N6G78_18805	COG3391	amine dehydrogenase activity
N6G78_18810	COG3391	amine dehydrogenase activity
N6G78_18815	COG0457	Tetratricopeptide repeat
N6G78_18835	COG1131	(ABC) transporter
N6G78_18845	COG0010	Belongs to the arginase family
N6G78_18850	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N6G78_18855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N6G78_18865	COG1994	Peptidase M50
N6G78_18870	COG1942	4-Oxalocrotonate Tautomerase
N6G78_18875	COG1846	Transcriptional regulator
N6G78_18880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N6G78_18890	COG0477	Major facilitator Superfamily
N6G78_18895	COG1959	2 iron, 2 sulfur cluster binding
N6G78_18900	COG3465	dGTPase activity
N6G78_18905	COG1078	dGTPase activity
N6G78_18910	COG4844	belongs to the
N6G78_18920	COG0697	spore germination
N6G78_18925	COG0095	Lipoate-protein ligase
N6G78_18930	COG0583	DNA-binding transcription factor activity
N6G78_18935	COG0280	phosphate acetyltransferase
N6G78_18940	COG3253	May function as heme-dependent peroxidase
N6G78_18945	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_18950	COG0436	Aminotransferase
N6G78_18955	COG2814	Major facilitator Superfamily
N6G78_18960	COG0151	Belongs to the GarS family
N6G78_18965	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_18970	COG1917	Cupin 2, conserved barrel domain protein
N6G78_18975	COG0077	Prephenate dehydratase
N6G78_18980	COG2814	Major facilitator Superfamily
N6G78_18985	COG0833	amino acid
N6G78_18990	COG4187	Peptidase family M20/M25/M40
N6G78_18995	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_19000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N6G78_19010	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N6G78_19015	COG1091	dTDP-4-dehydrorhamnose reductase activity
N6G78_19020	COG1088	dTDP-glucose 4,6-dehydratase activity
N6G78_19025	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
N6G78_19030	COG3980	spore coat polysaccharide biosynthesis protein
N6G78_19035	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
N6G78_19040	COG2089	acid synthase
N6G78_19045	COG0456	acetyltransferase
N6G78_19050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N6G78_19055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N6G78_19060	COG0463	Glycosyl transferase, family 2
N6G78_19070	COG2363	Small membrane protein
N6G78_19075	COG2233	PERMEase
N6G78_19085	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_19090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N6G78_19095	COG1216	Glycosyl transferase, family 2
N6G78_19100	COG0351	phosphomethylpyrimidine kinase
N6G78_19110	COG1621	beta-fructofuranosidase activity
N6G78_19115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N6G78_19115	COG1263	PTS System
N6G78_19125	COG3711	transcriptional antiterminator
N6G78_19135	COG1404	Belongs to the peptidase S8 family
N6G78_19140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N6G78_19145	COG0778	Nitroreductase
N6G78_19150	COG0772	Belongs to the SEDS family
N6G78_19160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N6G78_19165	COG1845	cytochrome c oxidase, subunit III
N6G78_19170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N6G78_19175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N6G78_19180	COG2261	transglycosylase associated protein
N6G78_19185	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
N6G78_19190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
N6G78_19195	COG2246	polysaccharide biosynthetic process
N6G78_19200	COG1309	transcriptional regulator
N6G78_19210	COG3162	membrane
N6G78_19215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N6G78_19220	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N6G78_19225	COG2837	iron assimilation
N6G78_19230	COG2822	iron ion transport
N6G78_19235	COG0672	)-iron permease
N6G78_19240	COG0352	thiamine-phosphate diphosphorylase activity
N6G78_19245	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
N6G78_19250	COG0583	DNA-binding transcription factor activity
N6G78_19255	COG1380	Effector of murein hydrolase LrgA
N6G78_19260	COG1346	cytolysis
N6G78_19265	COG2814	Major facilitator Superfamily
N6G78_19270	COG4895	conserved protein (DUF2196)
N6G78_19275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N6G78_19280	COG0346	lactoylglutathione lyase activity
N6G78_19290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N6G78_19295	COG1404	Belongs to the peptidase S8 family
N6G78_19300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N6G78_19300	COG1263	PTS System
N6G78_19305	COG3711	transcriptional antiterminator
N6G78_19310	COG1442	glycosyl transferase family 8
N6G78_19315	COG5522	Integral membrane protein (intg_mem_TP0381)
N6G78_19320	COG1846	Transcriptional regulator
N6G78_19325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N6G78_19330	COG2234	aminopeptidase activity
N6G78_19335	COG2357	RelA SpoT domain protein
N6G78_19340	COG1575	Belongs to the MenA family. Type 1 subfamily
N6G78_19355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N6G78_19360	COG1696	Membrane protein involved in D-alanine export
N6G78_19365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N6G78_19370	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
N6G78_19375	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
N6G78_19380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N6G78_19385	COG1486	melibiose metabolic process
N6G78_19390	COG1447	Phosphotransferase system cellobiose-specific component IIA
N6G78_19395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N6G78_19400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N6G78_19405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N6G78_19405	COG3711	transcriptional antiterminator
N6G78_19415	COG2094	Belongs to the DNA glycosylase MPG family
N6G78_19420	COG0753	catalase activity
N6G78_19425	COG2814	Major facilitator Superfamily
N6G78_19430	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N6G78_19435	COG1131	(ABC) transporter
N6G78_19455	COG1595	DNA-templated transcription, initiation
N6G78_19460	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N6G78_19465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N6G78_19470	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N6G78_19475	COG4988	ABC transporter
N6G78_19480	COG1294	oxidase, subunit
N6G78_19485	COG1271	oxidase subunit
N6G78_19490	COG3493	citrate carrier protein
N6G78_19495	COG0501	Belongs to the peptidase M48B family
N6G78_19505	COG0726	polysaccharide deacetylase
N6G78_19510	COG3842	ATPase activity
N6G78_19515	COG2508	Transcriptional regulator
N6G78_19520	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_19525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N6G78_19535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N6G78_19540	COG1881	PFAM PEBP family protein
N6G78_19545	COG0583	DNA-binding transcription factor activity
N6G78_19555	COG4585	Histidine kinase
N6G78_19560	COG2197	response regulator
N6G78_19565	COG2195	Cleaves the N-terminal amino acid of tripeptides
N6G78_19580	COG4894	glucomannan catabolic process
N6G78_19585	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N6G78_19590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N6G78_19595	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_19600	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N6G78_19605	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N6G78_19610	COG2610	gluconate transmembrane transporter activity
N6G78_19615	COG0500	methyltransferase
N6G78_19620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N6G78_19635	COG0693	protein deglycase activity
N6G78_19635	COG0753	catalase activity
N6G78_19640	COG2851	Citrate transporter
N6G78_19645	COG2273	Hydrolase Family 16
N6G78_19650	COG3711	transcriptional antiterminator
N6G78_19660	COG2270	Major facilitator Superfamily
N6G78_19665	COG0513	Belongs to the DEAD box helicase family
N6G78_19670	COG3401	FG-GAP repeat protein
N6G78_19670	COG2755	lipolytic protein G-D-S-L family
N6G78_19690	COG0697	spore germination
N6G78_19695	COG0589	response to stress
N6G78_19700	COG2723	6-phospho-beta-galactosidase activity
N6G78_19705	COG1263	PTS System
N6G78_19705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N6G78_19705	COG2190	(PTS) system
N6G78_19755	COG5444	nuclease activity
N6G78_19780	COG0494	nUDIX hydrolase
N6G78_19785	COG3507	Belongs to the glycosyl hydrolase 43 family
N6G78_19800	COG2986	histidine ammonia-lyase
N6G78_19805	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N6G78_19810	COG1228	amidohydrolase
N6G78_19815	COG0010	Belongs to the arginase family
N6G78_19820	COG0833	amino acid
N6G78_19825	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N6G78_19830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N6G78_19835	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N6G78_19840	COG2390	Transcriptional regulator
N6G78_19850	COG3192	ethanolamine utilization protein
N6G78_19855	COG2079	MmgE PrpD family protein
N6G78_19860	COG1473	amidohydrolase
N6G78_19865	COG1126	abc transporter atp-binding protein
N6G78_19870	COG0765	amino acid transport
N6G78_19875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N6G78_19880	COG0456	acetyltransferase
N6G78_19885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N6G78_19890	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
N6G78_19895	COG0561	phosphatase activity
N6G78_19925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N6G78_19930	COG5294	Protein conserved in bacteria
N6G78_19935	COG0577	efflux transmembrane transporter activity
N6G78_19940	COG1136	(ABC) transporter
N6G78_19945	COG2205	protein histidine kinase activity
N6G78_19950	COG0745	RESPONSE REGULATOR receiver
N6G78_19955	COG0191	fructose-bisphosphate aldolase activity
N6G78_19960	COG1082	Xylose isomerase domain protein TIM barrel
N6G78_19965	COG1082	Xylose isomerase domain protein TIM barrel
N6G78_19970	COG0673	inositol 2-dehydrogenase activity
N6G78_19975	COG2814	Major facilitator Superfamily
N6G78_19980	COG1082	Xylose isomerase domain protein TIM barrel
N6G78_19985	COG3962	Belongs to the TPP enzyme family
N6G78_19990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N6G78_20000	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_20005	COG1349	DNA-binding transcription factor activity
N6G78_20010	COG0667	Aldo Keto reductase
N6G78_20025	COG2814	Major facilitator Superfamily
N6G78_20030	COG0326	Molecular chaperone. Has ATPase activity
N6G78_20040	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_20045	COG1309	transcriptional regulator
N6G78_20050	COG1012	belongs to the aldehyde dehydrogenase family
N6G78_20055	COG1714	RDD family
N6G78_20060	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N6G78_20070	COG1714	RDD family
N6G78_20075	COG2311	Membrane
N6G78_20080	COG1917	Cupin 2, conserved barrel domain protein
N6G78_20085	COG1309	transcriptional regulator
N6G78_20090	COG1028	Short-chain dehydrogenase reductase Sdr
N6G78_20095	COG1846	Transcriptional regulator
N6G78_20100	COG1380	Effector of murein hydrolase LrgA
N6G78_20105	COG1346	cytolysis
N6G78_20110	COG5039	Polysaccharide pyruvyl transferase
N6G78_20115	COG1929	Belongs to the glycerate kinase type-1 family
N6G78_20120	COG1802	Transcriptional regulator
N6G78_20125	COG1070	Carbohydrate kinase
N6G78_20130	COG2610	gluconate transmembrane transporter activity
N6G78_20135	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N6G78_20140	COG0450	alkyl hydroperoxide reductase
N6G78_20145	COG3634	alkyl hydroperoxide reductase activity
N6G78_20155	COG2723	6-phospho-beta-galactosidase activity
N6G78_20160	COG2190	(PTS) system
N6G78_20165	COG2188	Transcriptional regulator
N6G78_20180	COG1131	(ABC) transporter
N6G78_20185	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
N6G78_20195	COG2189	Belongs to the N(4) N(6)-methyltransferase family
N6G78_20210	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N6G78_20225	COG1063	alcohol dehydrogenase
N6G78_20245	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
N6G78_20250	COG0456	acetyltransferase
N6G78_20255	COG0457	Tetratricopeptide repeat
N6G78_20265	COG0010	Belongs to the arginase family
N6G78_20270	COG0833	amino acid
N6G78_20275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N6G78_20280	COG3829	transcription factor binding
N6G78_20295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N6G78_20300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N6G78_20305	COG4853	Protein conserved in bacteria
N6G78_20310	COG4863	YycH protein
N6G78_20315	COG5002	protein histidine kinase activity
N6G78_20320	COG0745	RESPONSE REGULATOR receiver
N6G78_20350	COG0346	lactoylglutathione lyase activity
N6G78_20355	COG0305	Participates in initiation and elongation during chromosome replication
N6G78_20370	COG3093	addiction module antidote protein HigA
N6G78_20375	COG2807	transmembrane transport
N6G78_20380	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N6G78_20385	COG0359	binds to the 23S rRNA
N6G78_20390	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
N6G78_20395	COG4241	membrane
N6G78_20405	COG5577	PFAM Coat F domain
N6G78_20410	COG1733	regulation of RNA biosynthetic process
N6G78_20415	COG1227	inorganic diphosphatase activity
N6G78_20425	COG2271	Major facilitator Superfamily
N6G78_20430	COG4978	Transcriptional regulator
N6G78_20430	COG0789	Transcriptional regulator
N6G78_20440	COG4319	ketosteroid isomerase
N6G78_20445	COG1357	PFAM Pentapeptide repeats (8 copies)
N6G78_20450	COG2814	Major facilitator Superfamily
N6G78_20455	COG0583	DNA-binding transcription factor activity
N6G78_20460	COG2153	protein acetylation
N6G78_20470	COG0583	DNA-binding transcription factor activity
N6G78_20485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N6G78_20490	COG1846	Transcriptional regulator
N6G78_20495	COG2153	protein acetylation
N6G78_20500	COG2364	Membrane
N6G78_20505	COG0456	acetyltransferase
N6G78_20510	COG2315	Protein conserved in bacteria
N6G78_20515	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N6G78_20525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N6G78_20530	COG0798	PFAM Bile acid sodium symporter
N6G78_20535	COG0346	lactoylglutathione lyase activity
N6G78_20540	COG0640	Transcriptional regulator
N6G78_20550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N6G78_20560	COG0863	Belongs to the N(4) N(6)-methyltransferase family
N6G78_20570	COG1331	Highly conserved protein containing a thioredoxin domain
N6G78_20575	COG1266	CAAX protease self-immunity
N6G78_20580	COG0477	Major facilitator Superfamily
N6G78_20580	COG2814	Major facilitator Superfamily
N6G78_20585	COG0110	maltose O-acetyltransferase activity
N6G78_20590	COG0346	lactoylglutathione lyase activity
N6G78_20595	COG1609	Transcriptional regulator
N6G78_20600	COG0708	Exodeoxyribonuclease III
N6G78_20605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N6G78_20610	COG0629	single-stranded DNA binding
N6G78_20615	COG0360	Binds together with S18 to 16S ribosomal RNA
N6G78_20620	COG0012	GTP binding
N6G78_20625	COG0243	molybdopterin cofactor binding
N6G78_20630	COG4481	Protein conserved in bacteria
N6G78_20635	COG3949	Membrane
N6G78_20645	COG1475	DNA binding
N6G78_20650	COG1192	Involved in chromosome partitioning
N6G78_20660	COG1475	DNA binding
N6G78_20665	COG0357	Ribosomal RNA small subunit methyltransferase G
N6G78_20670	COG0445	tRNA wobble uridine modification
N6G78_20675	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N6G78_20680	COG1847	R3H domain protein
N6G78_20685	COG0706	membrane insertase activity
N6G78_20690	COG0594	ribonuclease P activity