locus-tag	class	description
OSK17_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OSK17_00010	COG0592	DNA-directed DNA polymerase activity
OSK17_00015	COG2501	S4 domain
OSK17_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OSK17_00030	COG0187	DNA topoisomerase II activity
OSK17_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OSK17_00070	COG0516	GMP reductase activity
OSK17_00070	COG0517	IMP dehydrogenase activity
OSK17_00075	COG1686	Belongs to the peptidase S11 family
OSK17_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OSK17_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OSK17_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OSK17_00100	COG1428	Deoxynucleoside kinase
OSK17_00105	COG1428	Deoxynucleoside kinase
OSK17_00110	COG1388	LysM domain
OSK17_00110	COG3858	chitin binding
OSK17_00115	COG1335	isochorismatase
OSK17_00120	COG0590	tRNA wobble adenosine to inosine editing
OSK17_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OSK17_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OSK17_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OSK17_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OSK17_00190	COG3853	Toxic anion resistance protein (TelA)
OSK17_00195	COG1982	Orn Lys Arg decarboxylase major
OSK17_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OSK17_00205	COG3870	Protein conserved in bacteria
OSK17_00210	COG1728	Protein conserved in bacteria
OSK17_00215	COG0470	DNA polymerase III
OSK17_00220	COG1774	PSP1 C-terminal conserved region
OSK17_00225	COG4467	Involved in initiation control of chromosome replication
OSK17_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OSK17_00235	COG2827	Endonuclease containing a URI domain
OSK17_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OSK17_00245	COG2002	toxin-antitoxin pair type II binding
OSK17_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OSK17_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OSK17_00255	COG0084	hydrolase, TatD family'
OSK17_00260	COG3583	domain protein
OSK17_00260	COG3584	3D domain protein
OSK17_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OSK17_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OSK17_00280	COG4466	Protein conserved in bacteria
OSK17_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OSK17_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OSK17_00300	COG0251	oxidation-reduction process
OSK17_00305	COG2088	sporulation resulting in formation of a cellular spore
OSK17_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OSK17_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OSK17_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OSK17_00325	COG0193	aminoacyl-tRNA hydrolase activity
OSK17_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OSK17_00340	COG2002	toxin-antitoxin pair type II binding
OSK17_00345	COG2244	polysaccharide biosynthetic process
OSK17_00350	COG3956	TIGRFAM MazG family protein
OSK17_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OSK17_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OSK17_00375	COG1098	S1 RNA binding domain
OSK17_00390	COG2208	phosphoserine phosphatase activity
OSK17_00395	COG2304	oxidoreductase activity
OSK17_00400	COG0515	serine threonine protein kinase
OSK17_00405	COG0037	tRNA processing
OSK17_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OSK17_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OSK17_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OSK17_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OSK17_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OSK17_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OSK17_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OSK17_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
OSK17_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OSK17_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OSK17_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OSK17_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OSK17_00470	COG1396	sequence-specific DNA binding
OSK17_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OSK17_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OSK17_00560	COG4463	regulation of RNA biosynthetic process
OSK17_00565	COG3880	PFAM UvrB UvrC protein
OSK17_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OSK17_00575	COG0542	response to heat
OSK17_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OSK17_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OSK17_00590	COG4956	integral membrane protein (PIN domain superfamily)
OSK17_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OSK17_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OSK17_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OSK17_00610	COG1045	serine acetyltransferase
OSK17_00615	COG0215	cysteine-tRNA ligase activity
OSK17_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OSK17_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OSK17_00630	COG3688	RNA-binding protein containing a PIN domain
OSK17_00635	COG1595	DNA-templated transcription, initiation
OSK17_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OSK17_00650	COG0250	Participates in transcription elongation, termination and antitermination
OSK17_00660	COG0081	regulation of translation
OSK17_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OSK17_00675	COG2813	Specifically methylates the guanine in position
OSK17_00680	COG0085	RNA polymerase activity
OSK17_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OSK17_00690	COG1358	cellular component organization or biogenesis
OSK17_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OSK17_00700	COG0049	tRNA binding
OSK17_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OSK17_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OSK17_00715	COG0596	Alpha beta hydrolase
OSK17_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OSK17_00730	COG0088	Forms part of the polypeptide exit tunnel
OSK17_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OSK17_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OSK17_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OSK17_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OSK17_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OSK17_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OSK17_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OSK17_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OSK17_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OSK17_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OSK17_00820	COG0200	Binds to the 23S rRNA
OSK17_00825	COG0201	protein transport
OSK17_00830	COG0563	adenylate kinase activity
OSK17_00835	COG0024	Methionine aminopeptidase
OSK17_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
OSK17_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OSK17_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OSK17_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OSK17_00865	COG0202	RNA polymerase activity
OSK17_00870	COG0203	ribosomal protein L17
OSK17_00875	COG1122	ATPase activity
OSK17_00880	COG1122	ATPase activity
OSK17_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OSK17_00890	COG0101	tRNA pseudouridine synthase activity
OSK17_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OSK17_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OSK17_00905	COG2226	methyltransferase
OSK17_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
OSK17_00920	COG0489	protein tyrosine kinase activity
OSK17_00930	COG2194	sulfuric ester hydrolase activity
OSK17_00935	COG0726	polysaccharide deacetylase
OSK17_01020	COG0659	secondary active sulfate transmembrane transporter activity
OSK17_01025	COG0385	Bile acid
OSK17_01030	COG2819	hydrolase of the alpha beta superfamily
OSK17_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSK17_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSK17_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OSK17_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OSK17_01050	COG2207	Transcriptional regulator
OSK17_01055	COG3876	Protein conserved in bacteria
OSK17_01060	COG1472	Belongs to the glycosyl hydrolase 3 family
OSK17_01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OSK17_01070	COG1263	PTS System
OSK17_01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_01075	COG1737	Transcriptional regulator
OSK17_01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OSK17_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OSK17_01090	COG1683	Conserved Protein
OSK17_01120	COG1595	DNA-templated transcription, initiation
OSK17_01125	COG5662	AntiSigma factor
OSK17_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OSK17_01135	COG4856	YbbR-like protein
OSK17_01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OSK17_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OSK17_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OSK17_01160	COG2169	Transcriptional regulator
OSK17_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OSK17_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OSK17_01175	COG3002	Belongs to the UPF0753 family
OSK17_01180	COG0288	reversible hydration of carbon dioxide
OSK17_01190	COG5609	conserved protein (DUF2294)
OSK17_01195	COG0640	Transcriptional regulator
OSK17_01200	COG2814	Major facilitator Superfamily
OSK17_01215	COG0515	serine threonine protein kinase
OSK17_01230	COG1113	amino acid transport
OSK17_01245	COG2602	Beta-lactamase
OSK17_01250	COG2124	cytochrome p450
OSK17_01260	COG0531	amino acid
OSK17_01265	COG0584	glycerophosphoryl diester phosphodiesterase
OSK17_01270	COG2271	Major facilitator Superfamily
OSK17_01280	COG0456	acetyltransferase
OSK17_01280	COG1846	Transcriptional regulator
OSK17_01285	COG2271	Major facilitator Superfamily
OSK17_01295	COG3409	Peptidoglycan-binding domain 1 protein
OSK17_01300	COG0697	spore germination
OSK17_01305	COG1917	Cupin 2, conserved barrel domain protein
OSK17_01305	COG2207	Transcriptional regulator
OSK17_01310	COG1397	ADP-ribosylglycohydrolase
OSK17_01315	COG5444	nuclease activity
OSK17_01320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OSK17_01325	COG3591	Belongs to the peptidase S1B family
OSK17_01335	COG0596	Alpha beta hydrolase
OSK17_01340	COG1183	phosphatidylcholine synthase activity
OSK17_01345	COG0586	Pfam SNARE associated Golgi protein
OSK17_01350	COG0688	phosphatidylethanolamine metabolic process
OSK17_01360	COG2312	Erythromycin esterase
OSK17_01365	COG1054	Belongs to the UPF0176 family
OSK17_01370	COG1301	dicarboxylic acid transport
OSK17_01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_01375	COG1263	PTS System
OSK17_01375	COG2190	(PTS) system
OSK17_01380	COG0363	glucosamine-6-phosphate deaminase activity
OSK17_01385	COG2188	Transcriptional regulator
OSK17_01395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OSK17_01400	COG0833	amino acid
OSK17_01405	COG2040	homocysteine
OSK17_01410	COG1115	amino acid carrier protein
OSK17_01415	COG2066	Belongs to the glutaminase family
OSK17_01420	COG4191	Histidine kinase
OSK17_01425	COG0784	Response regulator, receiver
OSK17_01430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OSK17_01435	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_01440	COG2271	Major facilitator Superfamily
OSK17_01445	COG4948	Mandelate Racemase Muconate Lactonizing
OSK17_01450	COG2186	Transcriptional regulator
OSK17_01455	COG2721	sulfolactate sulfo-lyase activity
OSK17_01460	COG3173	Aminoglycoside phosphotransferase
OSK17_01470	COG0697	spore germination
OSK17_01475	COG0745	RESPONSE REGULATOR receiver
OSK17_01480	COG2205	protein histidine kinase activity
OSK17_01485	COG1131	(ABC) transporter
OSK17_01505	COG3773	Cell wall hydrolase
OSK17_01510	COG2304	oxidoreductase activity
OSK17_01520	COG3540	Alkaline phosphatase
OSK17_01525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OSK17_01530	COG0805	protein transport
OSK17_01535	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OSK17_01540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OSK17_01545	COG0477	Major facilitator Superfamily
OSK17_01550	COG1309	transcriptional regulator
OSK17_01555	COG0252	asparaginase activity
OSK17_01560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OSK17_01565	COG1714	RDD family
OSK17_01570	COG3012	SEC-C Motif Domain Protein
OSK17_01570	COG1405	negative regulation of cell septum assembly
OSK17_01575	COG3290	protein histidine kinase activity
OSK17_01580	COG3279	Response regulator of the LytR AlgR family
OSK17_01585	COG4555	ABC transporter
OSK17_01590	COG1668	transmembrane transport
OSK17_01595	COG0667	Aldo Keto reductase
OSK17_01610	COG1595	DNA-templated transcription, initiation
OSK17_01615	COG1595	DNA-templated transcription, initiation
OSK17_01620	COG1876	peptidase activity
OSK17_01625	COG0457	Tetratricopeptide repeat
OSK17_01630	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_01635	COG0366	Alpha amylase catalytic
OSK17_01640	COG0803	Belongs to the bacterial solute-binding protein 9 family
OSK17_01645	COG1121	(ABC) transporter
OSK17_01650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OSK17_01655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OSK17_01660	COG2310	stress, protein
OSK17_01665	COG2310	stress, protein
OSK17_01670	COG2310	stress, protein
OSK17_01675	COG0861	Integral membrane protein TerC family
OSK17_01685	COG3853	Toxic anion resistance protein (TelA)
OSK17_01690	COG0477	Major facilitator Superfamily
OSK17_01695	COG2814	Major facilitator Superfamily
OSK17_01700	COG0640	Transcriptional regulator
OSK17_01705	COG0517	IMP dehydrogenase activity
OSK17_01705	COG4175	Glycine betaine
OSK17_01710	COG4176	ABC-type proline glycine betaine transport system permease component
OSK17_01715	COG2113	Glycine betaine
OSK17_01720	COG1473	amidohydrolase
OSK17_01725	COG1288	antiporter activity
OSK17_01735	COG0366	Alpha amylase catalytic
OSK17_01740	COG0039	L-malate dehydrogenase activity
OSK17_01745	COG1620	l-lactate permease
OSK17_01750	COG2814	Major facilitator Superfamily
OSK17_01755	COG1846	Transcriptional regulator
OSK17_01760	COG1280	lysine exporter protein (LysE YggA)
OSK17_01765	COG3403	YqcI/YcgG family
OSK17_01770	COG1113	amino acid transport
OSK17_01775	COG3665	Urea carboxylase-associated protein
OSK17_01780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OSK17_01785	COG1660	Displays ATPase and GTPase activities
OSK17_01790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OSK17_01795	COG2226	methyltransferase
OSK17_01800	COG0583	DNA-binding transcription factor activity
OSK17_01805	COG3458	cephalosporin-C deacetylase activity
OSK17_01810	COG3541	Predicted nucleotidyltransferase
OSK17_01815	COG0506	proline dehydrogenase activity
OSK17_01820	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_01825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OSK17_01830	COG2508	Transcriptional regulator
OSK17_01835	COG3689	TIGRFAM TIGR03943 family protein
OSK17_01840	COG0701	Predicted permease
OSK17_01845	COG2267	carboxylic ester hydrolase activity
OSK17_01850	COG0492	ferredoxin-NADP+ reductase activity
OSK17_01855	COG1587	Uroporphyrinogen-III synthase
OSK17_01855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OSK17_01860	COG2146	nitrite reductase [NAD(P)H] activity
OSK17_01865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OSK17_01870	COG0243	molybdopterin cofactor binding
OSK17_01875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OSK17_01880	COG2223	nitrite transmembrane transporter activity
OSK17_01885	COG1469	GTP cyclohydrolase I activity
OSK17_01890	COG1376	ErfK ybiS ycfS ynhG family protein
OSK17_01900	COG0523	cobalamin synthesis protein
OSK17_01905	COG0765	amino acid transport
OSK17_01910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSK17_01920	COG1714	RDD family
OSK17_01930	COG2723	6-phospho-beta-galactosidase activity
OSK17_01940	COG3209	COG3209 Rhs family protein
OSK17_01945	COG3290	protein histidine kinase activity
OSK17_01945	COG0840	transmembrane signaling receptor activity
OSK17_01950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OSK17_01955	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
OSK17_01960	COG1733	regulation of RNA biosynthetic process
OSK17_01965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_01995	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OSK17_02000	COG2814	Major facilitator Superfamily
OSK17_02010	COG0697	spore germination
OSK17_02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSK17_02025	COG2364	Membrane
OSK17_02030	COG1126	abc transporter atp-binding protein
OSK17_02035	COG0765	amino acid transport
OSK17_02040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSK17_02045	COG0583	DNA-binding transcription factor activity
OSK17_02050	COG0163	prenyltransferase activity
OSK17_02055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OSK17_02070	COG0596	Alpha beta hydrolase
OSK17_02075	COG3104	oligopeptide transport
OSK17_02080	COG5434	Belongs to the glycosyl hydrolase 28 family
OSK17_02090	COG0697	spore germination
OSK17_02100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OSK17_02105	COG1136	(ABC) transporter
OSK17_02110	COG0577	efflux transmembrane transporter activity
OSK17_02115	COG0745	RESPONSE REGULATOR receiver
OSK17_02120	COG3850	Histidine kinase
OSK17_02120	COG5002	protein histidine kinase activity
OSK17_02125	COG0457	Tetratricopeptide repeat
OSK17_02145	COG0527	aspartate kinase activity
OSK17_02150	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSK17_02155	COG4605	iron ion homeostasis
OSK17_02160	COG4604	ABC transporter, ATP-binding protein
OSK17_02165	COG4607	ABC-type enterochelin transport system periplasmic component
OSK17_02170	COG2814	Major facilitator Superfamily
OSK17_02175	COG1309	transcriptional regulator
OSK17_02180	COG0778	Nitroreductase
OSK17_02185	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OSK17_02190	COG0640	Transcriptional regulator
OSK17_02195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSK17_02200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OSK17_02205	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_02210	COG4975	Glucose uptake
OSK17_02215	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_02220	COG4549	nuclear export factor GLE1
OSK17_02225	COG1276	copper resistance
OSK17_02225	COG2372	response to copper ion
OSK17_02230	COG1349	DNA-binding transcription factor activity
OSK17_02240	COG2213	PTS system mannitol-specific
OSK17_02245	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OSK17_02250	COG0246	Mannitol dehydrogenase
OSK17_02255	COG0473	3-isopropylmalate dehydrogenase activity
OSK17_02260	COG0681	Belongs to the peptidase S26 family
OSK17_02265	COG0412	Dienelactone hydrolase
OSK17_02270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OSK17_02280	COG0561	phosphatase activity
OSK17_02285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OSK17_02290	COG1914	H( )-stimulated, divalent metal cation uptake system
OSK17_02295	COG4336	lyase activity
OSK17_02300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OSK17_02305	COG1984	allophanate hydrolase subunit 2
OSK17_02310	COG1414	Transcriptional regulator
OSK17_02315	COG2755	lipolytic protein G-D-S-L family
OSK17_02325	COG2329	Antibiotic biosynthesis monooxygenase
OSK17_02330	COG0768	penicillin binding
OSK17_02335	COG4989	oxidoreductase activity
OSK17_02340	COG3711	transcriptional antiterminator
OSK17_02345	COG0318	PFAM AMP-dependent synthetase and ligase
OSK17_02350	COG2226	methyltransferase
OSK17_02355	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_02360	COG1917	Cupin 2, conserved barrel domain protein
OSK17_02365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OSK17_02370	COG3871	stress protein (general stress protein 26)
OSK17_02380	COG2814	Major facilitator Superfamily
OSK17_02385	COG1522	sequence-specific DNA binding
OSK17_02390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OSK17_02390	COG0551	DNA topoisomerase type I activity
OSK17_02395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OSK17_02400	COG3706	GGDEF domain
OSK17_02405	COG5298	Protein conserved in bacteria
OSK17_02410	COG1215	transferase activity, transferring glycosyl groups
OSK17_02420	COG0531	amino acid
OSK17_02425	COG0494	nUDIX hydrolase
OSK17_02430	COG0028	Belongs to the TPP enzyme family
OSK17_02445	COG1914	H( )-stimulated, divalent metal cation uptake system
OSK17_02450	COG2261	transglycosylase associated protein
OSK17_02455	COG4876	unkown
OSK17_02460	COG2217	Heavy metal translocating P-type atpase
OSK17_02465	COG3729	General stress protein
OSK17_02470	COG0662	Cupin 2, conserved barrel domain protein
OSK17_02475	COG2329	Antibiotic biosynthesis monooxygenase
OSK17_02480	COG3546	catalase activity
OSK17_02485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OSK17_02490	COG3290	protein histidine kinase activity
OSK17_02495	COG4565	transcriptional regulatory protein
OSK17_02500	COG1301	dicarboxylic acid transport
OSK17_02505	COG0628	permease
OSK17_02510	COG1131	(ABC) transporter
OSK17_02515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OSK17_02525	COG1960	acyl-CoA dehydrogenase activity
OSK17_02540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OSK17_02545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSK17_02550	COG1181	Belongs to the D-alanine--D-alanine ligase family
OSK17_02555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OSK17_02560	COG0513	Belongs to the DEAD box helicase family
OSK17_02565	COG3402	PFAM membrane-flanked domain
OSK17_02570	COG3428	Bacterial PH domain
OSK17_02575	COG0705	Rhomboid family
OSK17_02580	COG0736	holo-[acyl-carrier-protein] synthase activity
OSK17_02585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OSK17_02590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OSK17_02595	COG0864	Transcriptional regulator
OSK17_02600	COG2337	Toxic component of a toxin-antitoxin (TA) module
OSK17_02605	COG1366	Belongs to the anti-sigma-factor antagonist family
OSK17_02610	COG1366	Belongs to the anti-sigma-factor antagonist family
OSK17_02615	COG2172	sigma factor antagonist activity
OSK17_02620	COG2208	phosphoserine phosphatase activity
OSK17_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
OSK17_02630	COG2172	sigma factor antagonist activity
OSK17_02635	COG1191	sigma factor activity
OSK17_02640	COG2208	phosphoserine phosphatase activity
OSK17_02645	COG2183	response to ionizing radiation
OSK17_02655	COG3091	SprT-like family
OSK17_02695	COG0582	viral genome integration into host DNA
OSK17_02710	COG0457	Tetratricopeptide repeat
OSK17_02735	COG5444	nuclease activity
OSK17_02745	COG1476	TRANSCRIPTIONal
OSK17_02755	COG3239	Fatty acid desaturase
OSK17_02760	COG1278	Cold shock
OSK17_02765	COG1329	Transcriptional regulator
OSK17_02770	COG0697	spore germination
OSK17_02775	COG2207	Transcriptional regulator
OSK17_02775	COG1917	Cupin 2, conserved barrel domain protein
OSK17_02780	COG0697	spore germination
OSK17_02785	COG2207	Transcriptional regulator
OSK17_02785	COG3708	Transcriptional regulator
OSK17_02790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSK17_02795	COG0477	Major facilitator Superfamily
OSK17_02805	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
OSK17_02820	COG1309	transcriptional regulator
OSK17_02825	COG0697	spore germination
OSK17_02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSK17_02835	COG2030	dehydratase
OSK17_02840	COG3545	Serine hydrolase
OSK17_02845	COG1733	regulation of RNA biosynthetic process
OSK17_02850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OSK17_02855	COG1733	regulation of RNA biosynthetic process
OSK17_02860	COG2249	NAD(P)H dehydrogenase (quinone) activity
OSK17_02865	COG2814	Major facilitator Superfamily
OSK17_02870	COG1309	transcriptional regulator
OSK17_02875	COG0640	Transcriptional regulator
OSK17_02880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OSK17_02890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OSK17_02895	COG0697	spore germination
OSK17_02900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSK17_02905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OSK17_02910	COG0640	Transcriptional regulator
OSK17_02915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OSK17_02930	COG4585	Histidine kinase
OSK17_02935	COG2197	response regulator
OSK17_02940	COG2409	Drug exporters of the RND superfamily
OSK17_02945	COG0596	Alpha beta hydrolase
OSK17_02950	COG1811	Na channel or pump
OSK17_02955	COG4978	Transcriptional regulator
OSK17_02955	COG0789	Transcriptional regulator
OSK17_02960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OSK17_02965	COG0778	Nitroreductase
OSK17_02970	COG0346	lactoylglutathione lyase activity
OSK17_02975	COG2259	Doxx family
OSK17_02980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSK17_03000	COG2323	membrane
OSK17_03005	COG2323	membrane
OSK17_03010	COG0071	Belongs to the small heat shock protein (HSP20) family
OSK17_03025	COG1309	transcriptional regulator
OSK17_03035	COG0456	acetyltransferase
OSK17_03040	COG0488	(ABC) transporter
OSK17_03045	COG1113	amino acid transport
OSK17_03050	COG2318	DinB family
OSK17_03055	COG1846	Transcriptional regulator
OSK17_03060	COG2409	Drug exporters of the RND superfamily
OSK17_03060	COG1033	growth of symbiont in host cell
OSK17_03065	COG0778	Nitroreductase
OSK17_03070	COG1846	Transcriptional regulator
OSK17_03075	COG2814	Major facilitator Superfamily
OSK17_03080	COG0730	response to heat
OSK17_03085	COG1802	Transcriptional regulator
OSK17_03090	COG3858	chitin binding
OSK17_03090	COG1388	LysM domain
OSK17_03095	COG1819	glycosyl
OSK17_03105	COG1785	Belongs to the alkaline phosphatase family
OSK17_03110	COG5646	InterPro IPR014922
OSK17_03120	COG0454	-acetyltransferase
OSK17_03125	COG1078	dGTPase activity
OSK17_03130	COG1388	LysM domain
OSK17_03135	COG2814	Major facilitator Superfamily
OSK17_03140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OSK17_03145	COG1447	Phosphotransferase system cellobiose-specific component IIA
OSK17_03150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OSK17_03155	COG2723	6-phospho-beta-galactosidase activity
OSK17_03160	COG2188	Transcriptional regulator
OSK17_03165	COG1940	carbohydrate kinase activity
OSK17_03170	COG1482	cell wall glycoprotein biosynthetic process
OSK17_03175	COG4124	Belongs to the glycosyl hydrolase 26 family
OSK17_03220	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OSK17_03225	COG0802	atpase or kinase
OSK17_03230	COG1214	PFAM Peptidase M22, glycoprotease
OSK17_03235	COG0456	acetyltransferase
OSK17_03240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OSK17_03245	COG0488	(ABC) transporter
OSK17_03250	COG0315	cyclic pyranopterin monophosphate synthase activity
OSK17_03255	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OSK17_03260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OSK17_03265	COG0805	protein transport
OSK17_03275	COG1266	CAAX protease self-immunity
OSK17_03285	COG0459	protein refolding
OSK17_03290	COG1073	alpha beta
OSK17_03295	COG0457	Tetratricopeptide repeat
OSK17_03300	COG1063	alcohol dehydrogenase
OSK17_03305	COG2211	Major facilitator Superfamily
OSK17_03310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OSK17_03315	COG1842	Phage shock protein A
OSK17_03320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OSK17_03325	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OSK17_03330	COG4260	virion core protein, lumpy skin disease virus
OSK17_03340	COG2814	Major facilitator Superfamily
OSK17_03345	COG1063	alcohol dehydrogenase
OSK17_03350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OSK17_03355	COG0823	Involved in the tonB-independent uptake of proteins
OSK17_03370	COG2267	carboxylic ester hydrolase activity
OSK17_03380	COG2132	Multicopper oxidase
OSK17_03385	COG1113	amino acid transport
OSK17_03395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OSK17_03400	COG0714	Associated with various cellular activities
OSK17_03405	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OSK17_03410	COG1305	Transglutaminase-like
OSK17_03415	COG0519	Catalyzes the synthesis of GMP from XMP
OSK17_03415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OSK17_03430	COG2252	PERMEase
OSK17_03435	COG3064	Membrane
OSK17_03445	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
OSK17_03455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OSK17_03460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OSK17_03465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OSK17_03470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OSK17_03475	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OSK17_03480	COG0047	phosphoribosylformylglycinamidine synthase activity
OSK17_03485	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OSK17_03490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OSK17_03495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OSK17_03500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OSK17_03505	COG0138	bifunctional purine biosynthesis protein purh
OSK17_03510	COG0151	Belongs to the GarS family
OSK17_03515	COG1522	sequence-specific DNA binding
OSK17_03520	COG0531	amino acid
OSK17_03530	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OSK17_03535	COG1470	cell adhesion involved in biofilm formation
OSK17_03540	COG4496	protein, YerC YecD
OSK17_03545	COG0069	glutamate synthase activity
OSK17_03550	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OSK17_03555	COG0210	DNA helicase
OSK17_03560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OSK17_03565	COG4851	CamS sex pheromone cAM373 precursor
OSK17_03570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OSK17_03575	COG1285	pathogenesis
OSK17_03580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OSK17_03585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OSK17_03590	COG0154	amidase activity
OSK17_03595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OSK17_03605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OSK17_03610	COG1597	lipid kinase activity
OSK17_03615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OSK17_03630	COG5444	nuclease activity
OSK17_03635	COG3391	amine dehydrogenase activity
OSK17_03640	COG0457	Tetratricopeptide repeat
OSK17_03650	COG0217	transcriptional regulatory protein
OSK17_03660	COG1309	transcriptional regulator
OSK17_03665	COG3631	Ketosteroid isomerase-related protein
OSK17_03685	COG3546	catalase activity
OSK17_03690	COG0454	-acetyltransferase
OSK17_03700	COG5578	integral membrane protein
OSK17_03705	COG2972	Histidine kinase
OSK17_03710	COG2207	Transcriptional regulator
OSK17_03710	COG4753	response regulator
OSK17_03715	COG1653	transport
OSK17_03720	COG1175	transmembrane transport
OSK17_03725	COG0395	ABC-type sugar transport system, permease component
OSK17_03730	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OSK17_03735	COG2207	Transcriptional regulator
OSK17_03740	COG2755	lipolytic protein G-D-S-L family
OSK17_03750	COG5578	integral membrane protein
OSK17_03755	COG3401	FG-GAP repeat protein
OSK17_03760	COG3401	FG-GAP repeat protein
OSK17_03765	COG2755	lipolytic protein G-D-S-L family
OSK17_03770	COG1874	Beta-galactosidase
OSK17_03780	COG1653	transport
OSK17_03785	COG4209	transmembrane transport
OSK17_03790	COG0395	ABC-type sugar transport system, permease component
OSK17_03795	COG1486	melibiose metabolic process
OSK17_03800	COG2323	membrane
OSK17_03805	COG2329	Antibiotic biosynthesis monooxygenase
OSK17_03810	COG0346	lactoylglutathione lyase activity
OSK17_03825	COG5583	Uncharacterized small protein (DUF2292)
OSK17_03830	COG0670	Belongs to the BI1 family
OSK17_03835	COG0697	spore germination
OSK17_03840	COG1846	Transcriptional regulator
OSK17_03845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OSK17_03865	COG1368	sulfuric ester hydrolase activity
OSK17_03875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OSK17_03880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OSK17_03885	COG1442	glycosyl transferase family 8
OSK17_03890	COG1216	Glycosyl transferase, family 2
OSK17_03895	COG1442	glycosyl transferase family 8
OSK17_03900	COG2223	nitrite transmembrane transporter activity
OSK17_03905	COG1011	Hydrolase
OSK17_03910	COG0531	amino acid
OSK17_03915	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_03920	COG0840	transmembrane signaling receptor activity
OSK17_03925	COG0488	(ABC) transporter
OSK17_03935	COG0789	Transcriptional regulator
OSK17_03940	COG2814	Major facilitator Superfamily
OSK17_03945	COG1404	Belongs to the peptidase S8 family
OSK17_03965	COG0488	(ABC) transporter
OSK17_03970	COG0513	Belongs to the DEAD box helicase family
OSK17_03975	COG0456	acetyltransferase
OSK17_03980	COG2130	NADP-dependent
OSK17_03985	COG1120	ATPase activity
OSK17_03990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSK17_03995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSK17_04000	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OSK17_04015	COG3866	Pectate lyase
OSK17_04020	COG0471	metal ion transport
OSK17_04025	COG3290	protein histidine kinase activity
OSK17_04030	COG4565	transcriptional regulatory protein
OSK17_04035	COG3181	Tripartite tricarboxylate transporter family receptor
OSK17_04045	COG2851	Citrate transporter
OSK17_04050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSK17_04055	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OSK17_04060	COG1254	Belongs to the acylphosphatase family
OSK17_04065	COG2258	MOSC domain
OSK17_04085	COG0024	Methionine aminopeptidase
OSK17_04090	COG1263	PTS System
OSK17_04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_04095	COG1368	sulfuric ester hydrolase activity
OSK17_04110	COG1115	amino acid carrier protein
OSK17_04115	COG0531	amino acid
OSK17_04130	COG0697	spore germination
OSK17_04135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_04135	COG1263	PTS System
OSK17_04140	COG0366	Alpha amylase catalytic
OSK17_04145	COG2188	Transcriptional regulator
OSK17_04150	COG0778	Nitroreductase
OSK17_04155	COG0737	Belongs to the 5'-nucleotidase family
OSK17_04160	COG0693	protein deglycase activity
OSK17_04165	COG2814	Major facilitator Superfamily
OSK17_04170	COG4840	Belongs to the UPF0435 family
OSK17_04175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OSK17_04180	COG4980	gas vesicle protein
OSK17_04185	COG1295	ribonuclease BN
OSK17_04190	COG0477	Major facilitator Superfamily
OSK17_04195	COG0387	Pfam Sodium calcium exchanger
OSK17_04205	COG0668	transmembrane transport
OSK17_04210	COG0535	radical SAM domain protein
OSK17_04220	COG0726	polysaccharide deacetylase
OSK17_04225	COG2084	Dehydrogenase
OSK17_04230	COG0598	Magnesium transport protein CorA
OSK17_04235	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OSK17_04240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OSK17_04250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OSK17_04255	COG4637	Psort location Cytoplasmic, score
OSK17_04265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OSK17_04270	COG0022	dehydrogenase e1 component
OSK17_04275	COG0508	dehydrogenase complex catalyzes the overall conversion of
OSK17_04280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OSK17_04285	COG3284	Transcriptional regulator
OSK17_04295	COG1742	UPF0060 membrane protein
OSK17_04320	COG4842	Belongs to the WXG100 family
OSK17_04325	COG1486	melibiose metabolic process
OSK17_04330	COG1737	Transcriptional regulator
OSK17_04335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_04335	COG1263	PTS System
OSK17_04340	COG5434	Belongs to the glycosyl hydrolase 28 family
OSK17_04345	COG1132	(ABC) transporter
OSK17_04350	COG1132	(ABC) transporter
OSK17_04355	COG2259	Doxx family
OSK17_04360	COG2514	catechol 2,3-dioxygenase activity
OSK17_04365	COG4585	Histidine kinase
OSK17_04370	COG2197	response regulator
OSK17_04375	COG1131	(ABC) transporter
OSK17_04380	COG0842	Transport permease protein
OSK17_04380	COG1511	domain protein
OSK17_04385	COG0842	Transport permease protein
OSK17_04390	COG1695	Transcriptional regulator
OSK17_04395	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OSK17_04400	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OSK17_04405	COG2318	DinB family
OSK17_04410	COG2814	Major facilitator Superfamily
OSK17_04415	COG1846	Transcriptional regulator
OSK17_04420	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OSK17_04420	COG0392	lysyltransferase activity
OSK17_04425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OSK17_04430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSK17_04435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSK17_04440	COG0384	phenazine biosynthesis protein PhzF
OSK17_04445	COG0778	Nitroreductase
OSK17_04460	COG1090	epimerase
OSK17_04465	COG2137	regulation of response to DNA damage stimulus
OSK17_04475	COG2814	Major facilitator Superfamily
OSK17_04490	COG3103	Sh3 type 3 domain protein
OSK17_04495	COG5658	integral membrane protein
OSK17_04500	COG0596	Alpha beta hydrolase
OSK17_04505	COG0463	Glycosyl transferase, family 2
OSK17_04510	COG4485	Bacterial membrane protein, YfhO
OSK17_04515	COG1988	membrane-bound metal-dependent
OSK17_04520	COG1194	a g-specific adenine glycosylase
OSK17_04530	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_04545	COG3557	Belongs to the UPF0374 family
OSK17_04550	COG1132	(ABC) transporter
OSK17_04555	COG4129	membrane
OSK17_04560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OSK17_04565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OSK17_04570	COG0735	belongs to the Fur family
OSK17_04680	COG4326	sporulation control protein
OSK17_04690	COG5577	PFAM Coat F domain
OSK17_04700	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OSK17_04715	COG0753	catalase activity
OSK17_04720	COG1116	anion transmembrane transporter activity
OSK17_04725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OSK17_04730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OSK17_04735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OSK17_04745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OSK17_04755	COG1476	TRANSCRIPTIONal
OSK17_04765	COG3382	B3 4 domain protein
OSK17_04770	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OSK17_04780	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OSK17_04785	COG0789	Transcriptional regulator
OSK17_04790	COG1664	Polymer-forming cytoskeletal
OSK17_04795	COG1664	Polymer-forming cytoskeletal
OSK17_04800	COG2766	serine protein kinase
OSK17_04805	COG2718	Belongs to the UPF0229 family
OSK17_04810	COG1846	Transcriptional regulator
OSK17_04815	COG1566	PFAM secretion protein HlyD family protein
OSK17_04820	COG2814	Major facilitator Superfamily
OSK17_04825	COG0655	NAD(P)H dehydrogenase (quinone) activity
OSK17_04845	COG1725	Transcriptional regulator
OSK17_04850	COG1131	(ABC) transporter
OSK17_04855	COG1131	(ABC) transporter
OSK17_04860	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OSK17_04865	COG1278	Cold shock
OSK17_04870	COG1464	Belongs to the NlpA lipoprotein family
OSK17_04875	COG3706	GGDEF domain
OSK17_04880	COG1823	symporter activity
OSK17_04910	COG5577	PFAM Coat F domain
OSK17_04915	COG1525	nuclease
OSK17_04915	COG4085	toxin activity
OSK17_04915	COG0737	Belongs to the 5'-nucleotidase family
OSK17_04920	COG3764	Sortase (surface protein transpeptidase)
OSK17_04925	COG0564	pseudouridine synthase activity
OSK17_04935	COG0517	IMP dehydrogenase activity
OSK17_04940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OSK17_04945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OSK17_04945	COG3153	acetyltransferase
OSK17_04950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OSK17_04955	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OSK17_04960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OSK17_04965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OSK17_04970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OSK17_04975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OSK17_04980	COG4585	Histidine kinase
OSK17_04980	COG2203	Gaf domain
OSK17_04985	COG2197	response regulator
OSK17_04990	COG0431	NADPH-dependent FMN reductase
OSK17_05005	COG1388	LysM domain
OSK17_05005	COG0791	NLP P60 protein
OSK17_05010	COG1959	2 iron, 2 sulfur cluster binding
OSK17_05015	COG0668	transmembrane transport
OSK17_05020	COG2719	SpoVR family
OSK17_05025	COG1785	Belongs to the alkaline phosphatase family
OSK17_05030	COG1388	LysM domain
OSK17_05030	COG0791	NLP P60 protein
OSK17_05035	COG0583	DNA-binding transcription factor activity
OSK17_05040	COG0372	Belongs to the citrate synthase family
OSK17_05045	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_05050	COG0531	amino acid
OSK17_05055	COG0733	neurotransmitter:sodium symporter activity
OSK17_05060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSK17_05065	COG0456	acetyltransferase
OSK17_05080	COG1595	DNA-templated transcription, initiation
OSK17_05085	COG0667	Aldo Keto reductase
OSK17_05090	COG0204	Acyl-transferase
OSK17_05095	COG1253	flavin adenine dinucleotide binding
OSK17_05100	COG0789	Transcriptional regulator
OSK17_05105	COG0436	Aminotransferase
OSK17_05110	COG1253	flavin adenine dinucleotide binding
OSK17_05115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OSK17_05120	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OSK17_05125	COG0584	glycerophosphoryl diester phosphodiesterase
OSK17_05135	COG0668	transmembrane transport
OSK17_05140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OSK17_05145	COG0726	polysaccharide deacetylase
OSK17_05150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OSK17_05155	COG1757	Na H antiporter
OSK17_05160	COG0589	response to stress
OSK17_05170	COG1132	(ABC) transporter
OSK17_05175	COG1132	(ABC) transporter
OSK17_05180	COG0702	epimerase
OSK17_05200	COG0189	ligase activity
OSK17_05205	COG0189	ligase activity
OSK17_05210	COG4399	Belongs to the UPF0754 family
OSK17_05215	COG3679	Belongs to the UPF0342 family
OSK17_05220	COG4335	DNA alkylation repair
OSK17_05225	COG0561	phosphatase activity
OSK17_05230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OSK17_05235	COG0475	glutathione-regulated potassium exporter activity
OSK17_05240	COG0490	domain, Protein
OSK17_05250	COG1024	Enoyl-CoA hydratase
OSK17_05260	COG4152	abc transporter atp-binding protein
OSK17_05265	COG1668	transmembrane transport
OSK17_05270	COG0420	3'-5' exonuclease activity
OSK17_05275	COG4717	serine-type aminopeptidase activity
OSK17_05280	COG3481	metal-dependent phosphohydrolase, HD sub domain
OSK17_05290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OSK17_05320	COG1846	Transcriptional regulator
OSK17_05325	COG4980	gas vesicle protein
OSK17_05340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OSK17_05345	COG0537	adenosine 5'-monophosphoramidase activity
OSK17_05350	COG1131	(ABC) transporter
OSK17_05355	COG4473	ABC transporter
OSK17_05365	COG1473	amidohydrolase
OSK17_05370	COG3069	C4-dicarboxylate transmembrane transporter activity
OSK17_05380	COG2329	Antibiotic biosynthesis monooxygenase
OSK17_05385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OSK17_05390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OSK17_05395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OSK17_05400	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OSK17_05405	COG1309	transcriptional regulator
OSK17_05410	COG1511	domain protein
OSK17_05415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OSK17_05420	COG4377	Putative membrane peptidase family (DUF2324)
OSK17_05430	COG1363	Peptidase, m42
OSK17_05435	COG4405	Protein conserved in bacteria
OSK17_05440	COG1301	dicarboxylic acid transport
OSK17_05450	COG1234	tRNA 3'-trailer cleavage
OSK17_05455	COG0095	Lipoate-protein ligase
OSK17_05460	COG0702	epimerase
OSK17_05465	COG0318	PFAM AMP-dependent synthetase and ligase
OSK17_05475	COG0501	Belongs to the peptidase M48B family
OSK17_05485	COG0456	acetyltransferase
OSK17_05490	COG0604	alcohol dehydrogenase
OSK17_05495	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OSK17_05500	COG0406	alpha-ribazole phosphatase activity
OSK17_05505	COG0183	Belongs to the thiolase family
OSK17_05510	COG0318	PFAM AMP-dependent synthetase and ligase
OSK17_05515	COG1268	BioY protein
OSK17_05520	COG0840	transmembrane signaling receptor activity
OSK17_05525	COG0723	plastoquinol--plastocyanin reductase activity
OSK17_05525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OSK17_05530	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_05540	COG4903	ComK protein
OSK17_05545	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_05555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OSK17_05570	COG0398	Pfam SNARE associated Golgi protein
OSK17_05575	COG0681	Belongs to the peptidase S26 family
OSK17_05580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OSK17_05585	COG1846	Transcriptional regulator
OSK17_05595	COG0738	Major facilitator superfamily
OSK17_05600	COG0673	inositol 2-dehydrogenase activity
OSK17_05605	COG0561	phosphatase activity
OSK17_05610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OSK17_05615	COG1609	Transcriptional regulator
OSK17_05620	COG3180	Ammonia monooxygenase
OSK17_05625	COG0477	Major facilitator Superfamily
OSK17_05625	COG2814	Major facilitator Superfamily
OSK17_05630	COG4533	DNA binding
OSK17_05640	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
OSK17_05645	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OSK17_05650	COG1074	ATP-dependent DNA helicase activity
OSK17_05655	COG0420	3'-5' exonuclease activity
OSK17_05660	COG0419	ATPase involved in DNA repair
OSK17_05665	COG1403	HNH endonuclease
OSK17_05705	COG5337	Spore coat protein CotH
OSK17_05710	COG0179	Fumarylacetoacetate (FAA) hydrolase
OSK17_05720	COG1404	Belongs to the peptidase S8 family
OSK17_05730	COG0367	asparagine synthase
OSK17_05735	COG2318	DinB family
OSK17_05745	COG0534	Mate efflux family protein
OSK17_05750	COG1917	Cupin 2, conserved barrel domain protein
OSK17_05750	COG2207	Transcriptional regulator
OSK17_05755	COG1609	Transcriptional regulator
OSK17_05760	COG0673	inositol 2-dehydrogenase activity
OSK17_05765	COG2318	DinB family
OSK17_05770	COG1279	arginine transmembrane transporter activity
OSK17_05775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSK17_05780	COG1357	PFAM Pentapeptide repeats (8 copies)
OSK17_05785	COG2267	carboxylic ester hydrolase activity
OSK17_05790	COG0529	Catalyzes the synthesis of activated sulfate
OSK17_05795	COG2046	Belongs to the sulfate adenylyltransferase family
OSK17_05800	COG0175	sulfate reduction
OSK17_05805	COG2045	Belongs to the ComB family
OSK17_05810	COG1809	phosphosulfolactate synthase activity
OSK17_05815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OSK17_05820	COG4948	Mandelate Racemase Muconate Lactonizing
OSK17_05825	COG2814	Major facilitator Superfamily
OSK17_05830	COG0454	-acetyltransferase
OSK17_05835	COG2153	protein acetylation
OSK17_05840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OSK17_05840	COG0646	methionine synthase
OSK17_05845	COG1666	GTP binding
OSK17_05870	COG1695	Transcriptional regulator
OSK17_05885	COG3227	Zinc metalloprotease (Elastase)
OSK17_05890	COG1307	EDD domain protein, DegV family
OSK17_05895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OSK17_05915	COG0561	phosphatase activity
OSK17_05920	COG1073	alpha beta
OSK17_05925	COG2151	metal-sulfur cluster biosynthetic enzyme
OSK17_05935	COG0277	FAD linked oxidase domain protein
OSK17_05940	COG2271	Major facilitator Superfamily
OSK17_05945	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OSK17_05950	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OSK17_05960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OSK17_05965	COG0505	Belongs to the CarA family
OSK17_05970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OSK17_05975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OSK17_05990	COG2267	carboxylic ester hydrolase activity
OSK17_06000	COG1744	ABC transporter substrate-binding protein PnrA-like
OSK17_06015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OSK17_06020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OSK17_06025	COG5504	Zn-dependent protease
OSK17_06030	COG0444	Belongs to the ABC transporter superfamily
OSK17_06035	COG4608	Belongs to the ABC transporter superfamily
OSK17_06045	COG0601	transmembrane transport
OSK17_06050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OSK17_06060	COG0180	Tryptophanyl-tRNA synthetase
OSK17_06065	COG4166	transmembrane transport
OSK17_06070	COG0601	transmembrane transport
OSK17_06075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OSK17_06080	COG0444	Belongs to the ABC transporter superfamily
OSK17_06085	COG4608	Belongs to the ABC transporter superfamily
OSK17_06090	COG2814	Major facilitator Superfamily
OSK17_06095	COG0456	acetyltransferase
OSK17_06100	COG1393	Belongs to the ArsC family
OSK17_06105	COG0861	Integral membrane protein TerC family
OSK17_06115	COG4862	establishment of competence for transformation
OSK17_06125	COG4469	Competence protein
OSK17_06130	COG1164	Oligoendopeptidase f
OSK17_06140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OSK17_06145	COG2346	COG2346, Truncated hemoglobins
OSK17_06150	COG0741	lytic transglycosylase activity
OSK17_06155	COG4116	CYTH
OSK17_06165	COG2357	RelA SpoT domain protein
OSK17_06170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OSK17_06175	COG0564	pseudouridine synthase activity
OSK17_06180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OSK17_06185	COG0475	glutathione-regulated potassium exporter activity
OSK17_06185	COG0569	domain protein
OSK17_06190	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OSK17_06195	COG0352	thiamine-phosphate diphosphorylase activity
OSK17_06200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OSK17_06205	COG2104	thiamine diphosphate biosynthetic process
OSK17_06210	COG2022	thiamine diphosphate biosynthetic process
OSK17_06215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OSK17_06220	COG0351	phosphomethylpyrimidine kinase
OSK17_06225	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OSK17_06280	COG0210	DNA helicase
OSK17_06290	COG2153	protein acetylation
OSK17_06295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OSK17_06300	COG2382	esterase
OSK17_06305	COG0626	cystathionine gamma-synthase activity
OSK17_06310	COG0626	cystathionine gamma-synthase activity
OSK17_06315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OSK17_06320	COG5505	Protein of unknown function (DUF819)
OSK17_06335	COG2856	Zn peptidase
OSK17_06345	COG1525	nuclease
OSK17_06350	COG1396	sequence-specific DNA binding
OSK17_06365	COG3646	Phage regulatory protein
OSK17_06365	COG3645	SOS response
OSK17_06400	COG3935	DnaD domain protein
OSK17_06405	COG1484	DNA-dependent DNA replication
OSK17_06460	COG1595	DNA-templated transcription, initiation
OSK17_06495	COG5484	DNA packaging
OSK17_06565	COG3953	SLT domain
OSK17_06565	COG5280	Phage tail tape measure protein TP901
OSK17_06570	COG0791	NLP P60 protein
OSK17_06570	COG1388	LysM domain
OSK17_06630	COG5632	N-Acetylmuramoyl-L-alanine amidase
OSK17_06630	COG3409	Peptidoglycan-binding domain 1 protein
OSK17_06650	COG5444	nuclease activity
OSK17_06685	COG5444	nuclease activity
OSK17_06735	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OSK17_06740	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_06750	COG3711	transcriptional antiterminator
OSK17_06750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OSK17_06755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OSK17_06755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OSK17_06755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OSK17_06760	COG1482	cell wall glycoprotein biosynthetic process
OSK17_06770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OSK17_06780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OSK17_06795	COG0109	protoheme IX farnesyltransferase activity
OSK17_06805	COG0726	polysaccharide deacetylase
OSK17_06820	COG5504	Zn-dependent protease
OSK17_06825	COG2205	protein histidine kinase activity
OSK17_06835	COG3383	formate dehydrogenase (NAD+) activity
OSK17_06840	COG2427	Protein of unknown function (DUF1641)
OSK17_06850	COG1051	belongs to the nudix hydrolase family
OSK17_06860	COG2124	cytochrome p450
OSK17_06865	COG1819	glycosyl
OSK17_06885	COG1587	Uroporphyrinogen-III synthase
OSK17_06890	COG0390	transport system, permease component
OSK17_06895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OSK17_06900	COG0697	spore germination
OSK17_06905	COG4297	protein containing double-stranded beta helix domain
OSK17_06915	COG1252	NADH dehydrogenase
OSK17_06920	COG1904	glucuronate isomerase
OSK17_06925	COG2211	Major facilitator Superfamily
OSK17_06930	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
OSK17_06935	COG1063	alcohol dehydrogenase
OSK17_06940	COG1312	Catalyzes the dehydration of D-mannonate
OSK17_06945	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_06950	COG2271	Major facilitator Superfamily
OSK17_06955	COG1609	Transcriptional regulator
OSK17_06960	COG0246	Mannitol dehydrogenase
OSK17_06965	COG2721	sulfolactate sulfo-lyase activity
OSK17_06970	COG0730	response to heat
OSK17_06975	COG2318	DinB family
OSK17_06980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OSK17_06985	COG0457	Tetratricopeptide repeat
OSK17_06995	COG2350	Protein conserved in bacteria
OSK17_07000	COG3409	Peptidoglycan-binding domain 1 protein
OSK17_07000	COG1388	LysM domain
OSK17_07000	COG5632	N-Acetylmuramoyl-L-alanine amidase
OSK17_07010	COG4195	phage-related replication protein
OSK17_07015	COG3546	catalase activity
OSK17_07020	COG2856	Zn peptidase
OSK17_07025	COG1396	sequence-specific DNA binding
OSK17_07035	COG1522	sequence-specific DNA binding
OSK17_07040	COG1484	DNA-dependent DNA replication
OSK17_07060	COG1595	DNA-templated transcription, initiation
OSK17_07065	COG3728	DNA packaging
OSK17_07065	COG5484	DNA packaging
OSK17_07070	COG1783	phage Terminase large subunit
OSK17_07075	COG5518	Phage portal protein
OSK17_07080	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OSK17_07085	COG4653	Phage capsid family
OSK17_07135	COG3953	SLT domain
OSK17_07135	COG5412	phage tail tape measure protein
OSK17_07140	COG1652	LysM domain
OSK17_07145	COG4193	domain, Protein
OSK17_07155	COG3628	GPW Gp25 family protein
OSK17_07160	COG3299	homolog of phage Mu protein gp47
OSK17_07165	COG3778	Protein conserved in bacteria
OSK17_07205	COG3409	Peptidoglycan-binding domain 1 protein
OSK17_07205	COG5632	N-Acetylmuramoyl-L-alanine amidase
OSK17_07225	COG0306	phosphate transporter
OSK17_07230	COG1392	Phosphate transport regulator
OSK17_07235	COG0531	amino acid
OSK17_07240	COG0346	lactoylglutathione lyase activity
OSK17_07250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OSK17_07255	COG0463	Glycosyl transferase, family 2
OSK17_07265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OSK17_07270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OSK17_07275	COG2362	D-Aminopeptidase
OSK17_07280	COG0601	transmembrane transport
OSK17_07285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OSK17_07290	COG0444	Belongs to the ABC transporter superfamily
OSK17_07295	COG4166	transmembrane transport
OSK17_07300	COG1619	proteins homologs of microcin C7 resistance protein MccF
OSK17_07305	COG4948	Mandelate Racemase Muconate Lactonizing
OSK17_07310	COG0791	NLP P60 protein
OSK17_07315	COG4608	Belongs to the ABC transporter superfamily
OSK17_07320	COG2706	6-phosphogluconolactonase activity
OSK17_07325	COG1834	amidinotransferase
OSK17_07330	COG1607	acyl-coa hydrolase
OSK17_07335	COG1017	nitric oxide dioxygenase activity
OSK17_07335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OSK17_07345	COG2323	membrane
OSK17_07350	COG2318	DinB family
OSK17_07355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OSK17_07360	COG2076	Multidrug Resistance protein
OSK17_07365	COG2076	Multidrug Resistance protein
OSK17_07370	COG0788	formyltetrahydrofolate deformylase activity
OSK17_07375	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OSK17_07380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OSK17_07385	COG1764	response to oxidative stress
OSK17_07390	COG1846	Transcriptional regulator
OSK17_07395	COG1764	response to oxidative stress
OSK17_07405	COG0590	tRNA wobble adenosine to inosine editing
OSK17_07410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OSK17_07415	COG1404	Belongs to the peptidase S8 family
OSK17_07420	COG1366	Belongs to the anti-sigma-factor antagonist family
OSK17_07425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OSK17_07430	COG1122	ATPase activity
OSK17_07435	COG4721	ABC-type cobalt transport system, permease component
OSK17_07445	COG0745	RESPONSE REGULATOR receiver
OSK17_07450	COG5002	protein histidine kinase activity
OSK17_07450	COG3850	Histidine kinase
OSK17_07455	COG3212	peptidase
OSK17_07460	COG3212	peptidase
OSK17_07475	COG2239	Acts as a magnesium transporter
OSK17_07480	COG0789	Transcriptional regulator
OSK17_07495	COG1846	Transcriptional regulator
OSK17_07500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OSK17_07505	COG0726	polysaccharide deacetylase
OSK17_07510	COG1408	metallophosphoesterase
OSK17_07520	COG0463	Glycosyl transferase, family 2
OSK17_07525	COG3285	dna ligase
OSK17_07525	COG1793	dna ligase
OSK17_07530	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OSK17_07535	COG5001	Diguanylate cyclase
OSK17_07535	COG3300	MHYT domain
OSK17_07540	COG0586	Pfam SNARE associated Golgi protein
OSK17_07545	COG0861	Integral membrane protein TerC family
OSK17_07550	COG1191	sigma factor activity
OSK17_07570	COG0501	Belongs to the peptidase M48B family
OSK17_07575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OSK17_07590	COG3594	Acyltransferase
OSK17_07595	COG5002	protein histidine kinase activity
OSK17_07600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OSK17_07610	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OSK17_07615	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OSK17_07620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OSK17_07625	COG0436	Aminotransferase
OSK17_07630	COG1850	ribulose-bisphosphate carboxylase activity
OSK17_07635	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OSK17_07640	COG0235	Class ii aldolase
OSK17_07645	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OSK17_07650	COG3339	Conserved Protein
OSK17_07665	COG3852	Histidine kinase
OSK17_07670	COG1846	Transcriptional regulator
OSK17_07675	COG1360	Flagellar Motor Protein
OSK17_07680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OSK17_07685	COG0542	response to heat
OSK17_07690	COG3949	Membrane
OSK17_07695	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OSK17_07700	COG0720	synthase
OSK17_07705	COG0602	queuosine metabolic process
OSK17_07710	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OSK17_07715	COG1733	regulation of RNA biosynthetic process
OSK17_07720	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_07725	COG4641	Protein conserved in bacteria
OSK17_07725	COG1388	LysM domain
OSK17_07730	COG1388	LysM domain
OSK17_07735	COG3858	chitin binding
OSK17_07740	COG3858	chitin binding
OSK17_07750	COG4873	Protein conserved in bacteria
OSK17_07760	COG3773	Cell wall hydrolase
OSK17_07765	COG2244	polysaccharide biosynthetic process
OSK17_07770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSK17_07775	COG2217	Heavy metal translocating P-type atpase
OSK17_07785	COG0006	proline dipeptidase activity
OSK17_07790	COG1609	Transcriptional regulator
OSK17_07795	COG3711	transcriptional antiterminator
OSK17_07800	COG1263	PTS System
OSK17_07800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_07800	COG2190	(PTS) system
OSK17_07805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OSK17_07810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OSK17_07820	COG1533	DNA photolyase activity
OSK17_07825	COG0456	acetyltransferase
OSK17_07830	COG0840	transmembrane signaling receptor activity
OSK17_07835	COG2084	Dehydrogenase
OSK17_07840	COG4257	antibiotic catabolic process
OSK17_07845	COG2340	Cysteine-rich secretory protein family
OSK17_07850	COG0768	penicillin binding
OSK17_07855	COG4191	Histidine kinase
OSK17_07860	COG0436	Aminotransferase
OSK17_07870	COG0835	chemotaxis
OSK17_07870	COG0784	Response regulator, receiver
OSK17_07880	COG2814	Major facilitator Superfamily
OSK17_07885	COG1376	ErfK ybiS ycfS ynhG family protein
OSK17_07890	COG1408	metallophosphoesterase
OSK17_07895	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_07900	COG2200	EAL domain
OSK17_07905	COG4703	Protein of unknown function (DUF1797)
OSK17_07910	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
OSK17_07920	COG0517	IMP dehydrogenase activity
OSK17_07925	COG0583	DNA-binding transcription factor activity
OSK17_07930	COG0716	FMN binding
OSK17_07940	COG0716	FMN binding
OSK17_07945	COG2171	N-acyltransferase activity
OSK17_07950	COG1473	amidohydrolase
OSK17_07960	COG0668	transmembrane transport
OSK17_07965	COG0450	alkyl hydroperoxide reductase
OSK17_07970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSK17_07985	COG0746	molybdenum cofactor guanylyltransferase activity
OSK17_07990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OSK17_07995	COG0303	'Molybdopterin
OSK17_08000	COG1763	Mo-molybdopterin cofactor biosynthetic process
OSK17_08005	COG0314	molybdopterin synthase activity
OSK17_08010	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OSK17_08015	COG1132	(ABC) transporter
OSK17_08020	COG1132	(ABC) transporter
OSK17_08030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OSK17_08035	COG1136	(ABC) transporter
OSK17_08040	COG0577	efflux transmembrane transporter activity
OSK17_08045	COG1349	DNA-binding transcription factor activity
OSK17_08050	COG1105	Belongs to the carbohydrate kinase PfkB family
OSK17_08055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OSK17_08055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OSK17_08055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OSK17_08060	COG0681	Belongs to the peptidase S26 family
OSK17_08070	COG0488	(ABC) transporter
OSK17_08075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OSK17_08080	COG2309	aminopeptidase activity
OSK17_08090	COG1077	Cell shape determining protein MreB Mrl
OSK17_08095	COG2002	toxin-antitoxin pair type II binding
OSK17_08100	COG3852	Histidine kinase
OSK17_08105	COG2105	PFAM AIG2 family protein
OSK17_08105	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
OSK17_08110	COG0569	domain protein
OSK17_08115	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OSK17_08120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OSK17_08125	COG5503	Protein of unknown function (DUF1447)
OSK17_08130	COG0561	phosphatase activity
OSK17_08135	COG0242	peptide deformylase activity
OSK17_08145	COG0497	DNA recombination
OSK17_08150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OSK17_08155	COG0022	dehydrogenase e1 component
OSK17_08160	COG0508	dehydrogenase complex catalyzes the overall conversion of
OSK17_08165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OSK17_08170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSK17_08180	COG1982	Orn Lys Arg decarboxylase major
OSK17_08185	COG4476	Belongs to the UPF0223 family
OSK17_08190	COG4493	Belongs to the UPF0637 family
OSK17_08200	COG0483	inositol monophosphate 1-phosphatase activity
OSK17_08210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OSK17_08250	COG1217	gtp-binding protein TYPA
OSK17_08260	COG4896	Protein conserved in bacteria
OSK17_08270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OSK17_08275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OSK17_08280	COG2066	Belongs to the glutaminase family
OSK17_08285	COG4838	Belongs to the UPF0358 family
OSK17_08290	COG0772	Belongs to the SEDS family
OSK17_08295	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OSK17_08300	COG1612	heme a metabolic process
OSK17_08305	COG0109	protoheme IX farnesyltransferase activity
OSK17_08310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OSK17_08310	COG2010	Cytochrome c
OSK17_08315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OSK17_08320	COG1845	cytochrome c oxidase, subunit III
OSK17_08325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OSK17_08330	COG3336	cytochrome c oxidase
OSK17_08340	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OSK17_08345	COG2340	Cysteine-rich secretory protein family
OSK17_08360	COG3679	Belongs to the UPF0342 family
OSK17_08365	COG4471	UPF0298 protein
OSK17_08370	COG0742	ribosomal rna small subunit methyltransferase
OSK17_08375	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OSK17_08380	COG3314	Sporulation integral membrane protein YlbJ
OSK17_08385	COG1752	Esterase of the alpha-beta hydrolase superfamily
OSK17_08390	COG3480	Lon protease (S16) C-terminal proteolytic domain
OSK17_08395	COG1323	Belongs to the UPF0348 family
OSK17_08405	COG1399	metal-binding, possibly nucleic acid-binding protein
OSK17_08420	COG0454	-acetyltransferase
OSK17_08425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OSK17_08430	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OSK17_08435	COG2001	Belongs to the MraZ family
OSK17_08440	COG0275	rRNA processing
OSK17_08445	COG4839	cell division protein FtsL
OSK17_08450	COG0768	penicillin binding
OSK17_08455	COG0768	penicillin binding
OSK17_08460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OSK17_08465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OSK17_08470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OSK17_08475	COG0772	Belongs to the SEDS family
OSK17_08480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OSK17_08485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OSK17_08490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OSK17_08495	COG3879	Bacterial protein of unknown function (DUF881)
OSK17_08500	COG3879	Bacterial protein of unknown function (DUF881)
OSK17_08505	COG3856	small basic protein
OSK17_08510	COG0849	cell division
OSK17_08515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OSK17_08520	COG1404	Belongs to the peptidase S8 family
OSK17_08520	COG4412	M6 family metalloprotease domain protein
OSK17_08530	COG1191	sigma factor activity
OSK17_08535	COG1191	sigma factor activity
OSK17_08540	COG1119	ATPase activity
OSK17_08545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OSK17_08550	COG1873	PFAM PRC-barrel domain
OSK17_08555	COG1496	oxidoreductase activity
OSK17_08560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OSK17_08565	COG1799	cell septum assembly
OSK17_08570	COG0762	integral membrane protein
OSK17_08575	COG2302	S4 RNA-binding domain
OSK17_08580	COG3599	regulation of cell shape
OSK17_08585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OSK17_08590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OSK17_08595	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OSK17_08600	COG0564	pseudouridine synthase activity
OSK17_08605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OSK17_08610	COG2233	PERMEase
OSK17_08615	COG0540	Belongs to the ATCase OTCase family
OSK17_08620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OSK17_08625	COG0505	Belongs to the CarA family
OSK17_08630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OSK17_08635	COG0543	2 iron, 2 sulfur cluster binding
OSK17_08640	COG0167	dihydroorotate dehydrogenase activity
OSK17_08645	COG0284	orotidine-5'-phosphate decarboxylase activity
OSK17_08650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OSK17_08655	COG0175	sulfate reduction
OSK17_08660	COG0306	phosphate transporter
OSK17_08665	COG2046	Belongs to the sulfate adenylyltransferase family
OSK17_08670	COG0529	Catalyzes the synthesis of activated sulfate
OSK17_08675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OSK17_08680	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
OSK17_08685	COG1648	precorrin-2 dehydrogenase activity
OSK17_08690	COG1293	RNA-binding protein homologous to eukaryotic snRNP
OSK17_08695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OSK17_08700	COG1561	YicC-like family, N-terminal region
OSK17_08710	COG0194	GDP metabolic process
OSK17_08715	COG1758	RNA polymerase activity
OSK17_08720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OSK17_08725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OSK17_08730	COG0242	peptide deformylase activity
OSK17_08735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OSK17_08740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OSK17_08740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OSK17_08745	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OSK17_08750	COG0631	protein serine/threonine phosphatase activity
OSK17_08755	COG0515	serine threonine protein kinase
OSK17_08755	COG2815	serine threonine protein kinase
OSK17_08760	COG1162	GTPase activity
OSK17_08765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OSK17_08770	COG1564	THIamine pyrophosphokinase
OSK17_08780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OSK17_08785	COG1302	Protein conserved in bacteria
OSK17_08790	COG1461	Dihydroxyacetone kinase
OSK17_08795	COG1760	l-serine dehydratase
OSK17_08800	COG1760	l-serine dehydratase
OSK17_08805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OSK17_08810	COG1349	DNA-binding transcription factor activity
OSK17_08810	COG2050	protein possibly involved in aromatic compounds catabolism
OSK17_08815	COG0416	fatty acid biosynthetic process
OSK17_08820	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OSK17_08825	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_08835	COG0571	ribonuclease III activity
OSK17_08840	COG1196	nuclear chromosome segregation
OSK17_08845	COG0552	protein localization to endoplasmic reticulum
OSK17_08855	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OSK17_08860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OSK17_08865	COG0228	four-way junction DNA binding
OSK17_08870	COG1837	Belongs to the UPF0109 family
OSK17_08880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OSK17_08885	COG0336	Belongs to the RNA methyltransferase TrmD family
OSK17_08890	COG0335	large ribosomal subunit rRNA binding
OSK17_08895	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OSK17_08900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OSK17_08910	COG2257	FlhB HrpN YscU SpaS Family
OSK17_08915	COG0045	succinate-CoA ligase (ADP-forming) activity
OSK17_08920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OSK17_08925	COG0758	DNA mediated transformation
OSK17_08930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OSK17_08935	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OSK17_08940	COG4974	Belongs to the 'phage' integrase family
OSK17_08945	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OSK17_08950	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OSK17_08955	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OSK17_08960	COG1815	bacterial-type flagellum-dependent cell motility
OSK17_08965	COG1558	bacterial-type flagellum-dependent cell motility
OSK17_08970	COG1677	Flagellar hook-basal body complex protein FliE
OSK17_08975	COG1766	The M ring may be actively involved in energy transduction
OSK17_08980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OSK17_08985	COG1317	bacterial-type flagellum organization
OSK17_08990	COG1157	protein secretion by the type III secretion system
OSK17_08995	COG2882	bacterial-type flagellum organization
OSK17_09000	COG3334	PFAM MgtE intracellular
OSK17_09005	COG3144	bacterial-type flagellum assembly
OSK17_09010	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OSK17_09015	COG4786	Flagellar basal body rod
OSK17_09020	COG1582	Flagellar protein (FlbD)
OSK17_09025	COG1580	Controls the rotational direction of flagella during chemotaxis
OSK17_09030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OSK17_09035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OSK17_09035	COG1776	CheC inhibitor of MCP methylation
OSK17_09040	COG2201	protein-glutamate methylesterase activity
OSK17_09045	COG3190	flagellar
OSK17_09050	COG1338	Plays a role in the flagellum-specific transport system
OSK17_09055	COG1987	bacterial-type flagellum assembly
OSK17_09060	COG1684	flagellar biosynthetic protein fliR
OSK17_09065	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OSK17_09070	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OSK17_09075	COG1419	protein localization to endoplasmic reticulum
OSK17_09080	COG0455	bacterial-type flagellum organization
OSK17_09085	COG2201	protein-glutamate methylesterase activity
OSK17_09090	COG0643	Histidine kinase
OSK17_09090	COG2198	Histidine kinase
OSK17_09095	COG0835	chemotaxis
OSK17_09100	COG1776	CheC inhibitor of MCP methylation
OSK17_09105	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OSK17_09110	COG1191	sigma factor activity
OSK17_09120	COG0052	Belongs to the universal ribosomal protein uS2 family
OSK17_09125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OSK17_09130	COG0528	UMP kinase activity
OSK17_09135	COG0233	cytoplasmic translational termination
OSK17_09140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OSK17_09145	COG4589	Belongs to the CDS family
OSK17_09150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OSK17_09155	COG0750	zinc metalloprotease
OSK17_09160	COG0442	prolyl-tRNA aminoacylation
OSK17_09165	COG2176	DNA-directed DNA polymerase activity
OSK17_09190	COG0779	Required for maturation of 30S ribosomal subunits
OSK17_09195	COG0195	Participates in both transcription termination and antitermination
OSK17_09200	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OSK17_09205	COG1358	cellular component organization or biogenesis
OSK17_09210	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OSK17_09215	COG1550	Protein conserved in bacteria
OSK17_09220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OSK17_09225	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OSK17_09230	COG0196	riboflavin kinase activity
OSK17_09235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OSK17_09240	COG1185	polyribonucleotide nucleotidyltransferase activity
OSK17_09245	COG0726	polysaccharide deacetylase
OSK17_09250	COG0612	Peptidase, M16
OSK17_09255	COG1873	PFAM PRC-barrel domain
OSK17_09260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OSK17_09265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OSK17_09270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OSK17_09275	COG0527	aspartate kinase activity
OSK17_09280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OSK17_09285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OSK17_09290	COG0740	serine-type endopeptidase activity
OSK17_09300	COG4980	gas vesicle protein
OSK17_09300	COG1674	ftsk spoiiie
OSK17_09305	COG2188	Transcriptional regulator
OSK17_09310	COG2814	Major facilitator Superfamily
OSK17_09315	COG0612	Peptidase, M16
OSK17_09320	COG0612	Peptidase, M16
OSK17_09325	COG0300	oxidoreductase activity
OSK17_09340	COG1426	Protein conserved in bacteria
OSK17_09345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OSK17_09350	COG1546	Belongs to the CinA family
OSK17_09350	COG1058	Belongs to the CinA family
OSK17_09355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OSK17_09360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OSK17_09365	COG1418	mRNA catabolic process
OSK17_09370	COG1692	metallophosphoesterase
OSK17_09375	COG2359	stage V sporulation protein S
OSK17_09380	COG1063	alcohol dehydrogenase
OSK17_09385	COG0156	8-amino-7-oxononanoate synthase activity
OSK17_09390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OSK17_09395	COG4550	Control of competence regulator ComK, YlbF/YmcA
OSK17_09405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OSK17_09410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OSK17_09425	COG3226	Transcriptional regulator
OSK17_09430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSK17_09440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OSK17_09445	COG3321	synthase
OSK17_09450	COG2070	2-Nitropropane dioxygenase
OSK17_09450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OSK17_09455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSK17_09460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OSK17_09465	COG3425	synthase
OSK17_09470	COG1024	Enoyl-CoA hydratase
OSK17_09475	COG1024	Enoyl-CoA hydratase
OSK17_09480	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_09480	COG0318	PFAM AMP-dependent synthetase and ligase
OSK17_09480	COG0300	oxidoreductase activity
OSK17_09480	COG3321	synthase
OSK17_09480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_09485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSK17_09485	COG4221	oxidoreductase activity
OSK17_09485	COG3321	synthase
OSK17_09485	COG0300	oxidoreductase activity
OSK17_09490	COG3321	synthase
OSK17_09490	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_09490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_09490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OSK17_09490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSK17_09495	COG3321	synthase
OSK17_09495	COG4221	oxidoreductase activity
OSK17_09495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_09495	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_09500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OSK17_09500	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OSK17_09500	COG3321	synthase
OSK17_09500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSK17_09505	COG2124	cytochrome p450
OSK17_09515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSK17_09520	COG1404	Belongs to the peptidase S8 family
OSK17_09530	COG4195	phage-related replication protein
OSK17_09535	COG1764	response to oxidative stress
OSK17_09540	COG2076	Multidrug Resistance protein
OSK17_09545	COG2076	Multidrug Resistance protein
OSK17_09560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OSK17_09565	COG1923	regulation of RNA biosynthetic process
OSK17_09580	COG1780	Probably involved in ribonucleotide reductase function
OSK17_09585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OSK17_09590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OSK17_09595	COG4112	unkown
OSK17_09600	COG0860	N-Acetylmuramoyl-L-alanine amidase
OSK17_09605	COG0464	growth
OSK17_09610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OSK17_09615	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OSK17_09620	COG0789	Transcriptional regulator
OSK17_09625	COG0174	glutamine synthetase
OSK17_09650	COG4282	regulation of fungal-type cell wall biogenesis
OSK17_09660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OSK17_09690	COG0135	phosphoribosylanthranilate isomerase activity
OSK17_09695	COG2211	Major facilitator Superfamily
OSK17_09700	COG3507	Belongs to the glycosyl hydrolase 43 family
OSK17_09705	COG1940	carbohydrate kinase activity
OSK17_09710	COG2115	Belongs to the xylose isomerase family
OSK17_09715	COG1070	Carbohydrate kinase
OSK17_09730	COG2814	Major facilitator Superfamily
OSK17_09735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OSK17_09750	COG0756	dUTP diphosphatase activity
OSK17_09790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OSK17_09805	COG3832	glyoxalase III activity
OSK17_09820	COG0697	spore germination
OSK17_09825	COG0531	amino acid
OSK17_09855	COG4195	phage-related replication protein
OSK17_09865	COG0346	lactoylglutathione lyase activity
OSK17_09875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OSK17_09880	COG1388	LysM domain
OSK17_09885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OSK17_09890	COG4224	UPF0291 protein
OSK17_09895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OSK17_09905	COG3763	UPF0154 protein
OSK17_09915	COG0785	Cytochrome C biogenesis protein
OSK17_09920	COG2201	protein-glutamate methylesterase activity
OSK17_09925	COG4846	Membrane protein involved in cytochrome C biogenesis
OSK17_09935	COG0071	Belongs to the small heat shock protein (HSP20) family
OSK17_09950	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OSK17_09955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSK17_09975	COG0824	Thioesterase
OSK17_09985	COG4841	protein insertion into membrane
OSK17_09990	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OSK17_09995	COG1832	CoA-binding protein
OSK17_10000	COG0187	DNA topoisomerase II activity
OSK17_10005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OSK17_10020	COG1115	amino acid carrier protein
OSK17_10025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OSK17_10035	COG5520	Belongs to the glycosyl hydrolase 30 family
OSK17_10040	COG3507	Belongs to the glycosyl hydrolase 43 family
OSK17_10045	COG2246	polysaccharide biosynthetic process
OSK17_10050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OSK17_10055	COG0586	Pfam SNARE associated Golgi protein
OSK17_10060	COG2404	hydrolase activity, acting on ester bonds
OSK17_10065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OSK17_10070	COG1024	Enoyl-CoA hydratase
OSK17_10075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OSK17_10080	COG0511	ligase activity, forming carbon-carbon bonds
OSK17_10085	COG0439	Biotin carboxylase
OSK17_10090	COG0318	PFAM AMP-dependent synthetase and ligase
OSK17_10095	COG1960	acyl-CoA dehydrogenase activity
OSK17_10105	COG1649	PFAM Uncharacterised BCR, COG1649
OSK17_10115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_10115	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OSK17_10120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_10125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_10130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_10135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_10140	COG2027	D-alanyl-D-alanine carboxypeptidase
OSK17_10145	COG2017	converts alpha-aldose to the beta-anomer
OSK17_10150	COG0534	Mate efflux family protein
OSK17_10165	COG0582	viral genome integration into host DNA
OSK17_10170	COG0166	Belongs to the GPI family
OSK17_10175	COG0405	Gamma-glutamyltransferase
OSK17_10180	COG0583	DNA-binding transcription factor activity
OSK17_10190	COG0493	'glutamate synthase
OSK17_10195	COG0069	glutamate synthase activity
OSK17_10195	COG0070	glutamate synthase
OSK17_10195	COG0067	glutamate synthase
OSK17_10200	COG0583	DNA-binding transcription factor activity
OSK17_10205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OSK17_10210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OSK17_10220	COG0300	oxidoreductase activity
OSK17_10225	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OSK17_10235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OSK17_10250	COG1131	(ABC) transporter
OSK17_10260	COG2814	Major facilitator Superfamily
OSK17_10265	COG1070	Carbohydrate kinase
OSK17_10270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OSK17_10275	COG0243	molybdopterin cofactor binding
OSK17_10285	COG2814	Major facilitator Superfamily
OSK17_10290	COG0673	inositol 2-dehydrogenase activity
OSK17_10295	COG1082	Xylose isomerase domain protein TIM barrel
OSK17_10300	COG1609	Transcriptional regulator
OSK17_10320	COG0840	transmembrane signaling receptor activity
OSK17_10320	COG5278	phosphoserine phosphatase activity
OSK17_10325	COG2368	4-hydroxyphenylacetate
OSK17_10330	COG4305	rare lipoprotein A
OSK17_10335	COG3619	membrane
OSK17_10340	COG3866	Pectate lyase
OSK17_10345	COG2135	peptidase activity
OSK17_10355	COG2140	Oxalate decarboxylase
OSK17_10380	COG2720	vancomycin resistance protein
OSK17_10395	COG3739	integral membrane protein
OSK17_10400	COG0583	DNA-binding transcription factor activity
OSK17_10405	COG0697	spore germination
OSK17_10415	COG0693	protein deglycase activity
OSK17_10420	COG2367	Beta-lactamase
OSK17_10440	COG0574	Belongs to the PEP-utilizing enzyme family
OSK17_10440	COG3848	Pyruvate phosphate dikinase
OSK17_10445	COG0726	polysaccharide deacetylase
OSK17_10450	COG2314	TM2 domain
OSK17_10510	COG0457	Tetratricopeptide repeat
OSK17_10535	COG4282	regulation of fungal-type cell wall biogenesis
OSK17_10540	COG1231	oxidoreductase activity
OSK17_10545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OSK17_10550	COG0662	Cupin 2, conserved barrel domain protein
OSK17_10550	COG2207	Transcriptional regulator
OSK17_10555	COG0456	acetyltransferase
OSK17_10560	COG1309	transcriptional regulator
OSK17_10565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSK17_10570	COG3708	Transcriptional regulator
OSK17_10575	COG2378	regulation of single-species biofilm formation
OSK17_10585	COG0640	Transcriptional regulator
OSK17_10590	COG0741	lytic transglycosylase activity
OSK17_10595	COG2322	membrane
OSK17_10610	COG1619	proteins homologs of microcin C7 resistance protein MccF
OSK17_10615	COG3239	Fatty acid desaturase
OSK17_10620	COG4585	Histidine kinase
OSK17_10625	COG2197	response regulator
OSK17_10630	COG3584	3D domain protein
OSK17_10630	COG1388	LysM domain
OSK17_10635	COG0514	ATP-dependent DNA helicase (RecQ)
OSK17_10645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OSK17_10650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OSK17_10665	COG0071	Belongs to the small heat shock protein (HSP20) family
OSK17_10690	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_10695	COG1657	PFAM Prenyltransferase squalene oxidase
OSK17_10700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OSK17_10705	COG0733	neurotransmitter:sodium symporter activity
OSK17_10710	COG0385	Bile acid
OSK17_10715	COG0508	dehydrogenase complex catalyzes the overall conversion of
OSK17_10720	COG0567	Dehydrogenase, E1 component
OSK17_10725	COG4548	von Willebrand factor, type A
OSK17_10730	COG0714	Associated with various cellular activities
OSK17_10735	COG2032	superoxide dismutase activity
OSK17_10740	COG0791	NLP P60 protein
OSK17_10740	COG1388	LysM domain
OSK17_10745	COG1819	glycosyl
OSK17_10750	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OSK17_10755	COG0534	Mate efflux family protein
OSK17_10760	COG1366	Belongs to the anti-sigma-factor antagonist family
OSK17_10765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OSK17_10770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OSK17_10780	COG2962	Rard protein
OSK17_10795	COG2610	gluconate transmembrane transporter activity
OSK17_10800	COG1942	4-Oxalocrotonate Tautomerase
OSK17_10805	COG1733	regulation of RNA biosynthetic process
OSK17_10810	COG0778	Nitroreductase
OSK17_10815	COG0400	carboxylic ester hydrolase activity
OSK17_10820	COG0346	lactoylglutathione lyase activity
OSK17_10830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OSK17_10835	COG3409	Peptidoglycan-binding domain 1 protein
OSK17_10835	COG0793	Belongs to the peptidase S41A family
OSK17_10840	COG2226	methyltransferase
OSK17_10850	COG1876	peptidase activity
OSK17_10855	COG0813	purine-nucleoside phosphorylase activity
OSK17_10870	COG0671	phosphoesterase, PA-phosphatase related
OSK17_10890	COG4479	Belongs to the UPF0346 family
OSK17_10920	COG3331	DNA recombination
OSK17_10965	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OSK17_11000	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OSK17_11005	COG0756	dUTP diphosphatase activity
OSK17_11010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSK17_11040	COG1780	Probably involved in ribonucleotide reductase function
OSK17_11140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OSK17_11165	COG3584	3D domain protein
OSK17_11170	COG0587	DNA-directed DNA polymerase activity
OSK17_11175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OSK17_11180	COG0358	DNA primase activity
OSK17_11185	COG0305	Participates in initiation and elongation during chromosome replication
OSK17_11195	COG2887	Belongs to the helicase family. UvrD subfamily
OSK17_11230	COG2135	peptidase activity
OSK17_11235	COG1793	dna ligase
OSK17_11285	COG1388	LysM domain
OSK17_11345	COG3655	Transcriptional regulator
OSK17_11360	COG0582	viral genome integration into host DNA
OSK17_11420	COG3655	Transcriptional regulator
OSK17_11500	COG0776	regulation of translation
OSK17_11540	COG4373	Mu-like prophage FluMu protein gp28
OSK17_11640	COG0582	viral genome integration into host DNA
OSK17_11660	COG0739	heme binding
OSK17_11660	COG0741	lytic transglycosylase activity
OSK17_11660	COG1196	nuclear chromosome segregation
OSK17_11670	COG2433	Pfam Transposase IS66
OSK17_11680	COG4632	Exopolysaccharide biosynthesis protein
OSK17_11680	COG5434	Belongs to the glycosyl hydrolase 28 family
OSK17_11685	COG5632	N-Acetylmuramoyl-L-alanine amidase
OSK17_11700	COG0457	Tetratricopeptide repeat
OSK17_11705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OSK17_11715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OSK17_11720	COG2226	methyltransferase
OSK17_11725	COG2211	Major facilitator Superfamily
OSK17_11730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OSK17_11760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OSK17_11780	COG5444	nuclease activity
OSK17_11785	COG4282	regulation of fungal-type cell wall biogenesis
OSK17_11800	COG1525	nuclease
OSK17_11810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OSK17_11820	COG0456	acetyltransferase
OSK17_11825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OSK17_11830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OSK17_11835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OSK17_11840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OSK17_11855	COG0456	acetyltransferase
OSK17_11860	COG0463	Glycosyl transferase, family 2
OSK17_11875	COG4641	Protein conserved in bacteria
OSK17_11880	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
OSK17_11885	COG1086	Polysaccharide biosynthesis protein
OSK17_11890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OSK17_11895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OSK17_11900	COG1846	Transcriptional regulator
OSK17_11905	COG0534	Mate efflux family protein
OSK17_11915	COG4698	Protein conserved in bacteria
OSK17_11920	COG2755	lipolytic protein G-D-S-L family
OSK17_11925	COG1999	signal sequence binding
OSK17_11935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OSK17_11940	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OSK17_11945	COG1272	protein, Hemolysin III
OSK17_11950	COG0204	Acyl-transferase
OSK17_11955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OSK17_11960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OSK17_11970	COG2521	methyltransferase
OSK17_11970	COG2136	Putative SAM-dependent methyltransferase
OSK17_11980	COG0129	dihydroxy-acid dehydratase activity
OSK17_11985	COG1413	lyase activity
OSK17_11990	COG1418	mRNA catabolic process
OSK17_11995	COG0386	Belongs to the glutathione peroxidase family
OSK17_12000	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OSK17_12005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OSK17_12015	COG1278	Cold shock
OSK17_12035	COG0328	RNA-DNA hybrid ribonuclease activity
OSK17_12040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OSK17_12045	COG0328	RNA-DNA hybrid ribonuclease activity
OSK17_12055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OSK17_12070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OSK17_12080	COG1755	Isoprenylcysteine carboxyl methyltransferase
OSK17_12085	COG3424	synthase
OSK17_12090	COG2233	PERMEase
OSK17_12095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OSK17_12100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OSK17_12110	COG0800	Aldolase
OSK17_12115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OSK17_12120	COG1609	Transcriptional regulator
OSK17_12125	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OSK17_12130	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_12135	COG1199	ATP-dependent helicase activity
OSK17_12150	COG0116	Belongs to the methyltransferase superfamily
OSK17_12165	COG4474	Belongs to the UPF0398 family
OSK17_12180	COG3359	exonuclease
OSK17_12185	COG1205	dead DEAH box helicase
OSK17_12185	COG1111	helicase
OSK17_12190	COG2190	(PTS) system
OSK17_12195	COG0071	Belongs to the small heat shock protein (HSP20) family
OSK17_12230	COG3331	DNA recombination
OSK17_12235	COG4499	WXG100 protein secretion system (Wss), protein YukC
OSK17_12235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OSK17_12245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OSK17_12250	COG3935	DnaD domain protein
OSK17_12255	COG0017	Asparaginyl-tRNA synthetase
OSK17_12260	COG0436	Aminotransferase
OSK17_12265	COG5353	protein conserved in bacteria
OSK17_12275	COG1199	ATP-dependent helicase activity
OSK17_12275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OSK17_12280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OSK17_12285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OSK17_12290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OSK17_12295	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OSK17_12295	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OSK17_12300	COG0617	tRNA 3'-terminal CCA addition
OSK17_12305	COG0438	transferase activity, transferring glycosyl groups
OSK17_12310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OSK17_12315	COG1803	Methylglyoxal synthase
OSK17_12320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OSK17_12325	COG1694	Mazg nucleotide pyrophosphohydrolase
OSK17_12330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OSK17_12340	COG4347	Protein of unknown function (DUF1405)
OSK17_12345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OSK17_12345	COG2010	Cytochrome c
OSK17_12350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OSK17_12355	COG0723	plastoquinol--plastocyanin reductase activity
OSK17_12365	COG5582	Belongs to the UPF0302 family
OSK17_12370	COG0457	Tetratricopeptide repeat
OSK17_12375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OSK17_12380	COG0287	Prephenate dehydrogenase
OSK17_12385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OSK17_12395	COG0133	tryptophan synthase activity
OSK17_12400	COG0135	phosphoribosylanthranilate isomerase activity
OSK17_12410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OSK17_12415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OSK17_12420	COG4401	Chorismate mutase type I
OSK17_12425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OSK17_12430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OSK17_12435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OSK17_12440	COG0105	UTP biosynthetic process
OSK17_12445	COG0142	geranyltranstransferase activity
OSK17_12450	COG2226	methyltransferase
OSK17_12455	COG0142	geranyltranstransferase activity
OSK17_12465	COG0302	gtp cyclohydrolase
OSK17_12470	COG0776	regulation of translation
OSK17_12475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OSK17_12490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OSK17_12495	COG1160	GTP binding
OSK17_12520	COG1304	FMN binding
OSK17_12525	COG0539	negative regulation of cytoplasmic translation
OSK17_12530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OSK17_12540	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
OSK17_12545	COG2959	enzyme of heme biosynthesis
OSK17_12550	COG3773	Cell wall hydrolase
OSK17_12550	COG3409	Peptidoglycan-binding domain 1 protein
OSK17_12555	COG2339	peptidase activity
OSK17_12560	COG0492	ferredoxin-NADP+ reductase activity
OSK17_12565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OSK17_12570	COG4862	establishment of competence for transformation
OSK17_12575	COG1408	metallophosphoesterase
OSK17_12585	COG1388	LysM domain
OSK17_12590	COG1266	CAAX protease self-immunity
OSK17_12595	COG0514	ATP-dependent DNA helicase (RecQ)
OSK17_12600	COG4955	Helix-turn-helix domain
OSK17_12605	COG1141	Ferredoxin
OSK17_12610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OSK17_12615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OSK17_12620	COG0710	3-dehydroquinate dehydratase activity
OSK17_12630	COG1595	DNA-templated transcription, initiation
OSK17_12635	COG5002	protein histidine kinase activity
OSK17_12640	COG0745	RESPONSE REGULATOR receiver
OSK17_12645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OSK17_12650	COG1333	cytochrome c biogenesis protein
OSK17_12655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSK17_12660	COG1187	pseudouridine synthase activity
OSK17_12665	COG0700	Nucleoside recognition
OSK17_12670	COG2715	membrane protein required for spore maturation
OSK17_12675	COG1686	Belongs to the peptidase S11 family
OSK17_12685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OSK17_12690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OSK17_12695	COG1547	Domain of unknown function (DUF309)
OSK17_12700	COG0456	acetyltransferase
OSK17_12705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OSK17_12710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OSK17_12710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OSK17_12715	COG0307	riboflavin synthase, alpha
OSK17_12720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OSK17_12720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OSK17_12730	COG0681	Belongs to the peptidase S26 family
OSK17_12750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OSK17_12755	COG4086	secreted protein
OSK17_12760	COG0019	diaminopimelate decarboxylase activity
OSK17_12765	COG0697	spore germination
OSK17_12780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OSK17_12800	COG1191	sigma factor activity
OSK17_12805	COG2172	sigma factor antagonist activity
OSK17_12810	COG1366	Belongs to the anti-sigma-factor antagonist family
OSK17_12815	COG1686	Belongs to the peptidase S11 family
OSK17_12820	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OSK17_12825	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OSK17_12830	COG4974	Belongs to the 'phage' integrase family
OSK17_12840	COG0735	belongs to the Fur family
OSK17_12845	COG1300	Membrane
OSK17_12855	COG0281	malic enzyme
OSK17_12860	COG1757	Na H antiporter
OSK17_12865	COG1027	Aspartate ammonia-lyase
OSK17_12870	COG0252	asparaginase activity
OSK17_12875	COG1396	sequence-specific DNA binding
OSK17_12880	COG1379	DNA repair
OSK17_12885	COG0494	nUDIX hydrolase
OSK17_12895	COG0667	Aldo Keto reductase
OSK17_12905	COG1073	alpha beta
OSK17_12915	COG4918	Iron-sulphur cluster biosynthesis
OSK17_12920	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OSK17_12920	COG0456	acetyltransferase
OSK17_12925	COG2329	Antibiotic biosynthesis monooxygenase
OSK17_12930	COG0456	acetyltransferase
OSK17_12940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OSK17_12955	COG2211	Major facilitator Superfamily
OSK17_12965	COG0346	lactoylglutathione lyase activity
OSK17_12970	COG1072	(Pantothenic acid kinase))
OSK17_12975	COG3048	D-serine ammonia-lyase activity
OSK17_12980	COG0300	oxidoreductase activity
OSK17_12985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSK17_12990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OSK17_12995	COG4187	Peptidase family M20/M25/M40
OSK17_13000	COG1902	pentaerythritol trinitrate reductase activity
OSK17_13005	COG0596	Alpha beta hydrolase
OSK17_13015	COG1234	tRNA 3'-trailer cleavage
OSK17_13020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OSK17_13025	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OSK17_13030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OSK17_13040	COG0706	membrane insertase activity
OSK17_13045	COG3361	conserved protein (COG2071)
OSK17_13050	COG2195	Cleaves the N-terminal amino acid of tripeptides
OSK17_13055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OSK17_13060	COG0346	lactoylglutathione lyase activity
OSK17_13070	COG1376	ErfK ybiS ycfS ynhG family protein
OSK17_13075	COG4129	membrane
OSK17_13080	COG1126	abc transporter atp-binding protein
OSK17_13085	COG0765	amino acid transport
OSK17_13090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSK17_13100	COG1597	lipid kinase activity
OSK17_13105	COG2814	Major facilitator Superfamily
OSK17_13110	COG4978	Transcriptional regulator
OSK17_13110	COG0789	Transcriptional regulator
OSK17_13115	COG0508	dehydrogenase complex catalyzes the overall conversion of
OSK17_13120	COG0022	dehydrogenase e1 component
OSK17_13125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OSK17_13130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OSK17_13135	COG3426	butyrate kinase activity
OSK17_13140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OSK17_13145	COG0280	phosphate acetyltransferase
OSK17_13150	COG3290	protein histidine kinase activity
OSK17_13150	COG3829	transcription factor binding
OSK17_13160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OSK17_13165	COG2079	MmgE PrpD family protein
OSK17_13170	COG0372	Belongs to the citrate synthase family
OSK17_13175	COG1960	acyl-CoA dehydrogenase activity
OSK17_13180	COG1250	3-hydroxyacyl-CoA dehydrogenase
OSK17_13185	COG0183	Belongs to the thiolase family
OSK17_13190	COG0584	glycerophosphoryl diester phosphodiesterase
OSK17_13195	COG0860	N-Acetylmuramoyl-L-alanine amidase
OSK17_13210	COG1902	pentaerythritol trinitrate reductase activity
OSK17_13215	COG0745	RESPONSE REGULATOR receiver
OSK17_13220	COG0750	zinc metalloprotease
OSK17_13225	COG0497	DNA recombination
OSK17_13230	COG1438	arginine binding
OSK17_13235	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OSK17_13240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OSK17_13245	COG0142	geranyltranstransferase activity
OSK17_13250	COG1722	exodeoxyribonuclease VII activity
OSK17_13255	COG1570	exodeoxyribonuclease VII activity
OSK17_13260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OSK17_13265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OSK17_13270	COG1302	Protein conserved in bacteria
OSK17_13275	COG0439	Biotin carboxylase
OSK17_13280	COG0511	ligase activity, forming carbon-carbon bonds
OSK17_13320	COG3854	ATPases associated with a variety of cellular activities
OSK17_13330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OSK17_13335	COG0006	proline dipeptidase activity
OSK17_13340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OSK17_13350	COG3872	metal-dependent enzyme
OSK17_13360	COG1752	Esterase of the alpha-beta hydrolase superfamily
OSK17_13365	COG1321	iron dependent repressor
OSK17_13370	COG0095	Lipoate-protein ligase
OSK17_13375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OSK17_13380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OSK17_13385	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OSK17_13390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OSK17_13395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OSK17_13410	COG1396	sequence-specific DNA binding
OSK17_13420	COG0681	Belongs to the peptidase S26 family
OSK17_13445	COG4940	Competence protein ComGF
OSK17_13455	COG4970	Tfp pilus assembly protein FimT
OSK17_13460	COG4537	Required for transformation and DNA binding
OSK17_13465	COG1459	type II secretion system
OSK17_13470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OSK17_13475	COG0598	Magnesium transport protein CorA
OSK17_13480	COG1253	flavin adenine dinucleotide binding
OSK17_13485	COG1366	Belongs to the anti-sigma-factor antagonist family
OSK17_13495	COG1393	Belongs to the ArsC family
OSK17_13505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSK17_13515	COG0011	TIGRFAM Protein of
OSK17_13525	COG2866	Carboxypeptidase
OSK17_13530	COG1368	sulfuric ester hydrolase activity
OSK17_13535	COG1940	carbohydrate kinase activity
OSK17_13540	COG4483	Protein conserved in bacteria
OSK17_13545	COG0705	Rhomboid family
OSK17_13545	COG0457	Tetratricopeptide repeat
OSK17_13555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OSK17_13565	COG0438	transferase activity, transferring glycosyl groups
OSK17_13580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OSK17_13585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OSK17_13590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OSK17_13595	COG0581	inorganic phosphate transmembrane transporter activity
OSK17_13600	COG0573	inorganic phosphate transmembrane transporter activity
OSK17_13605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OSK17_13610	COG0768	penicillin binding
OSK17_13615	COG0477	Major facilitator Superfamily
OSK17_13620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OSK17_13625	COG2839	Protein conserved in bacteria
OSK17_13630	COG5521	maltodextrose utilization protein MalA
OSK17_13635	COG1388	LysM domain
OSK17_13640	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OSK17_13645	COG4709	membrane
OSK17_13650	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
OSK17_13655	COG0735	belongs to the Fur family
OSK17_13660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OSK17_13670	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OSK17_13675	COG0513	Belongs to the DEAD box helicase family
OSK17_13685	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OSK17_13690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OSK17_13695	COG2384	SAM-dependent methyltransferase
OSK17_13700	COG2010	Cytochrome c
OSK17_13705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OSK17_13710	COG0358	DNA primase activity
OSK17_13715	COG1671	Belongs to the UPF0178 family
OSK17_13720	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OSK17_13725	COG0517	IMP dehydrogenase activity
OSK17_13730	COG0751	glycine-tRNA ligase activity
OSK17_13735	COG0752	glycyl-tRNA synthetase alpha subunit
OSK17_13740	COG1381	Involved in DNA repair and RecF pathway recombination
OSK17_13750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OSK17_13755	COG0295	cytidine deaminase activity
OSK17_13760	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OSK17_13765	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OSK17_13770	COG1480	7TM receptor with intracellular HD hydrolase
OSK17_13775	COG1702	phosphate starvation-inducible protein PhoH
OSK17_13780	COG0561	phosphatase activity
OSK17_13795	COG4864	UPF0365 protein
OSK17_13800	COG1030	water channel activity
OSK17_13805	COG1610	YqeY-like protein
OSK17_13815	COG1283	sodium-dependent phosphate transmembrane transporter activity
OSK17_13820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OSK17_13825	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OSK17_13830	COG2264	protein methyltransferase activity
OSK17_13835	COG0484	heat shock protein binding
OSK17_13840	COG0443	Heat shock 70 kDa protein
OSK17_13850	COG1420	regulation of RNA biosynthetic process
OSK17_13855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OSK17_13860	COG0481	GTPase activity
OSK17_13870	COG0860	N-Acetylmuramoyl-L-alanine amidase
OSK17_13875	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OSK17_13880	COG0268	Binds directly to 16S ribosomal RNA
OSK17_13885	COG1466	dna polymerase III delta subunit
OSK17_13900	COG2333	competence protein COMEC
OSK17_13900	COG0658	competence protein
OSK17_13905	COG2131	deaminase
OSK17_13910	COG1596	polysaccharide export
OSK17_13910	COG1555	photosystem II stabilization
OSK17_13915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OSK17_13920	COG2226	methyltransferase
OSK17_13925	COG0799	negative regulation of ribosome biogenesis
OSK17_13930	COG1713	HD superfamily hydrolase involved in NAD metabolism
OSK17_13935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OSK17_13940	COG1534	Rna-binding protein
OSK17_13945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OSK17_13950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OSK17_13955	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OSK17_13965	COG2755	lipolytic protein G-D-S-L family
OSK17_13970	COG5632	N-Acetylmuramoyl-L-alanine amidase
OSK17_13970	COG3409	Peptidoglycan-binding domain 1 protein
OSK17_13975	COG0398	Pfam SNARE associated Golgi protein
OSK17_13980	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OSK17_13990	COG3209	COG3209 Rhs family protein
OSK17_14000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OSK17_14010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OSK17_14015	COG0798	PFAM Bile acid sodium symporter
OSK17_14020	COG0346	lactoylglutathione lyase activity
OSK17_14025	COG0640	Transcriptional regulator
OSK17_14030	COG3403	YqcI/YcgG family
OSK17_14035	COG0457	Tetratricopeptide repeat
OSK17_14050	COG5444	nuclease activity
OSK17_14075	COG5632	N-Acetylmuramoyl-L-alanine amidase
OSK17_14075	COG3409	Peptidoglycan-binding domain 1 protein
OSK17_14080	COG4824	toxin secretion phage lysis holin
OSK17_14110	COG3778	Protein conserved in bacteria
OSK17_14115	COG3299	homolog of phage Mu protein gp47
OSK17_14120	COG3628	GPW Gp25 family protein
OSK17_14130	COG4193	domain, Protein
OSK17_14135	COG1652	LysM domain
OSK17_14140	COG5280	Phage tail tape measure protein TP901
OSK17_14140	COG3953	SLT domain
OSK17_14205	COG4653	Phage capsid family
OSK17_14210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OSK17_14220	COG2369	cell adhesion
OSK17_14225	COG5518	Phage portal protein
OSK17_14230	COG1783	phage Terminase large subunit
OSK17_14235	COG5484	DNA packaging
OSK17_14245	COG3677	Transposase
OSK17_14260	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
OSK17_14270	COG1484	DNA-dependent DNA replication
OSK17_14275	COG3935	DnaD domain protein
OSK17_14280	COG3723	Recombinational DNA repair protein, rece pathway
OSK17_14285	COG5377	YqaJ viral recombinase family
OSK17_14315	COG1476	TRANSCRIPTIONal
OSK17_14320	COG3620	sequence-specific DNA binding
OSK17_14330	COG0563	adenylate kinase activity
OSK17_14335	COG2856	Zn peptidase
OSK17_14360	COG3223	Belongs to the PsiE family
OSK17_14365	COG0642	Histidine kinase
OSK17_14365	COG5002	protein histidine kinase activity
OSK17_14370	COG0745	RESPONSE REGULATOR receiver
OSK17_14375	COG2311	Membrane
OSK17_14385	COG0454	-acetyltransferase
OSK17_14390	COG2249	NAD(P)H dehydrogenase (quinone) activity
OSK17_14400	COG0730	response to heat
OSK17_14405	COG0425	Belongs to the sulfur carrier protein TusA family
OSK17_14420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OSK17_14420	COG0425	Belongs to the sulfur carrier protein TusA family
OSK17_14430	COG2210	Belongs to the sulfur carrier protein TusA family
OSK17_14435	COG1937	Protein conserved in bacteria
OSK17_14445	COG0662	Cupin 2, conserved barrel domain protein
OSK17_14460	COG0789	Transcriptional regulator
OSK17_14460	COG4978	Transcriptional regulator
OSK17_14465	COG2814	Major facilitator Superfamily
OSK17_14470	COG0456	acetyltransferase
OSK17_14475	COG1253	flavin adenine dinucleotide binding
OSK17_14485	COG0697	spore germination
OSK17_14490	COG0583	DNA-binding transcription factor activity
OSK17_14495	COG2072	flavoprotein involved in K transport
OSK17_14500	COG1230	cation diffusion facilitator family transporter
OSK17_14505	COG1942	4-Oxalocrotonate Tautomerase
OSK17_14510	COG0583	DNA-binding transcription factor activity
OSK17_14520	COG1114	Component of the transport system for branched-chain amino acids
OSK17_14525	COG1687	branched-chain amino acid
OSK17_14530	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OSK17_14535	COG1522	sequence-specific DNA binding
OSK17_14540	COG2732	(Barnase) inhibitor
OSK17_14545	COG2124	cytochrome p450
OSK17_14560	COG1335	isochorismatase
OSK17_14575	COG2318	DinB family
OSK17_14585	COG2070	2-Nitropropane dioxygenase
OSK17_14590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OSK17_14600	COG2186	Transcriptional regulator
OSK17_14615	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_14620	COG3958	Transketolase
OSK17_14625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OSK17_14630	COG0477	Major facilitator Superfamily
OSK17_14635	COG1846	Transcriptional regulator
OSK17_14640	COG3443	Belongs to the bacterial solute-binding protein 9 family
OSK17_14645	COG1595	DNA-templated transcription, initiation
OSK17_14650	COG0667	Aldo Keto reductase
OSK17_14655	COG2851	Citrate transporter
OSK17_14660	COG0583	DNA-binding transcription factor activity
OSK17_14665	COG2828	Protein conserved in bacteria
OSK17_14670	COG3409	Peptidoglycan-binding domain 1 protein
OSK17_14675	COG5566	PFAM Mor transcription activator
OSK17_14680	COG0596	Alpha beta hydrolase
OSK17_14685	COG4991	sh3 domain protein
OSK17_14690	COG4991	sh3 domain protein
OSK17_14700	COG0346	lactoylglutathione lyase activity
OSK17_14710	COG5577	PFAM Coat F domain
OSK17_14715	COG1063	alcohol dehydrogenase
OSK17_14725	COG5577	PFAM Coat F domain
OSK17_14730	COG0789	Transcriptional regulator
OSK17_14740	COG1064	alcohol dehydrogenase
OSK17_14745	COG0693	protein deglycase activity
OSK17_14750	COG1621	beta-fructofuranosidase activity
OSK17_14760	COG3716	PTS system mannose fructose sorbose family IID component
OSK17_14765	COG3715	PTS system
OSK17_14770	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_14775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
OSK17_14780	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OSK17_14780	COG3933	PFAM sigma-54 factor interaction domain-containing protein
OSK17_14790	COG1113	amino acid transport
OSK17_14795	COG1280	lysine exporter protein (LysE YggA)
OSK17_14800	COG1378	Sugar-specific transcriptional regulator TrmB
OSK17_14805	COG1595	DNA-templated transcription, initiation
OSK17_14815	COG2755	lipolytic protein G-D-S-L family
OSK17_14815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OSK17_14825	COG2124	cytochrome p450
OSK17_14825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OSK17_14830	COG1309	transcriptional regulator
OSK17_14835	COG2226	methyltransferase
OSK17_14850	COG2116	formate transmembrane transporter activity
OSK17_14855	COG5609	conserved protein (DUF2294)
OSK17_14860	COG3383	formate dehydrogenase (NAD+) activity
OSK17_14865	COG2427	Protein of unknown function (DUF1641)
OSK17_14875	COG0626	cystathionine gamma-synthase activity
OSK17_14880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OSK17_14885	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OSK17_14890	COG2226	methyltransferase
OSK17_14905	COG0768	penicillin binding
OSK17_14910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OSK17_14915	COG0572	uridine kinase
OSK17_14920	COG0826	peptidase U32
OSK17_14925	COG0826	peptidase U32
OSK17_14930	COG4122	O-methyltransferase activity
OSK17_14935	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OSK17_14940	COG3906	Belongs to the UPF0473 family
OSK17_14945	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OSK17_14950	COG4472	Bacterial protein of unknown function (DUF965)
OSK17_14955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OSK17_14960	COG0628	permease
OSK17_14965	COG1126	abc transporter atp-binding protein
OSK17_14970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSK17_14975	COG0765	amino acid transport
OSK17_14980	COG0765	amino acid transport
OSK17_14995	COG3881	PFAM PRC-barrel domain
OSK17_15000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OSK17_15005	COG0457	Tetratricopeptide repeat
OSK17_15010	COG0482	sulfurtransferase activity
OSK17_15015	COG1104	cysteine desulfurase activity
OSK17_15020	COG1959	2 iron, 2 sulfur cluster binding
OSK17_15025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OSK17_15030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OSK17_15040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OSK17_15045	COG0124	histidyl-tRNA synthetase
OSK17_15055	COG4991	sh3 domain protein
OSK17_15055	COG3103	Sh3 type 3 domain protein
OSK17_15055	COG0860	N-Acetylmuramoyl-L-alanine amidase
OSK17_15060	COG1490	D-aminoacyl-tRNA deacylase activity
OSK17_15065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OSK17_15070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OSK17_15075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OSK17_15075	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OSK17_15080	COG5416	Lipopolysaccharide assembly protein A domain
OSK17_15085	COG0490	domain, Protein
OSK17_15090	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OSK17_15090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OSK17_15100	COG2244	polysaccharide biosynthetic process
OSK17_15105	COG2323	membrane
OSK17_15115	COG1862	Preprotein translocase
OSK17_15120	COG0343	queuine tRNA-ribosyltransferase activity
OSK17_15125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OSK17_15135	COG2255	four-way junction helicase activity
OSK17_15140	COG0632	four-way junction helicase activity
OSK17_15150	COG2814	Major facilitator Superfamily
OSK17_15155	COG0673	inositol 2-dehydrogenase activity
OSK17_15160	COG2112	serine threonine protein kinase
OSK17_15180	COG1115	amino acid carrier protein
OSK17_15185	COG0217	transcriptional regulatory protein
OSK17_15195	COG1388	LysM domain
OSK17_15200	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OSK17_15205	COG0157	Belongs to the NadC ModD family
OSK17_15210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OSK17_15215	COG1104	cysteine desulfurase activity
OSK17_15220	COG1827	regulation of RNA biosynthetic process
OSK17_15225	COG0077	Prephenate dehydratase
OSK17_15230	COG4492	Belongs to the UPF0735 family
OSK17_15235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OSK17_15240	COG3290	protein histidine kinase activity
OSK17_15250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OSK17_15255	COG2868	ribosomal protein
OSK17_15260	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OSK17_15265	COG1994	Peptidase M50
OSK17_15270	COG0739	heme binding
OSK17_15275	COG2894	cell division
OSK17_15280	COG0850	regulation of cytokinetic process
OSK17_15285	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OSK17_15295	COG1077	Cell shape determining protein MreB Mrl
OSK17_15300	COG2003	Belongs to the UPF0758 family
OSK17_15305	COG0424	maF-like protein
OSK17_15315	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OSK17_15320	COG0285	dihydrofolate synthase activity
OSK17_15325	COG0525	valine-tRNA ligase activity
OSK17_15335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OSK17_15340	COG1388	LysM domain
OSK17_15345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OSK17_15350	COG0113	porphobilinogen synthase activity
OSK17_15355	COG1587	Uroporphyrinogen-III synthase
OSK17_15360	COG0181	hydroxymethylbilane synthase activity
OSK17_15365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OSK17_15370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OSK17_15380	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OSK17_15385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OSK17_15390	COG0470	DNA polymerase III
OSK17_15390	COG1067	ATP-dependent peptidase activity
OSK17_15395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OSK17_15400	COG0544	peptidyl-prolyl cis-trans isomerase activity
OSK17_15405	COG1477	protein flavinylation
OSK17_15405	COG0457	Tetratricopeptide repeat
OSK17_15410	COG0066	3-isopropylmalate dehydratase activity
OSK17_15415	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OSK17_15420	COG0473	3-isopropylmalate dehydrogenase activity
OSK17_15425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OSK17_15430	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OSK17_15435	COG0440	acetolactate synthase activity
OSK17_15440	COG0028	Belongs to the TPP enzyme family
OSK17_15450	COG0454	-acetyltransferase
OSK17_15455	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
OSK17_15465	COG0622	Phosphoesterase
OSK17_15470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OSK17_15475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OSK17_15480	COG5401	PFAM Sporulation and spore germination
OSK17_15485	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OSK17_15490	COG1846	Transcriptional regulator
OSK17_15495	COG2197	response regulator
OSK17_15500	COG0824	Thioesterase
OSK17_15505	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OSK17_15510	COG1053	succinate dehydrogenase
OSK17_15515	COG2009	succinate dehydrogenase
OSK17_15520	COG1719	4-vinyl reductase, 4VR
OSK17_15525	COG0527	aspartate kinase activity
OSK17_15530	COG0322	excinuclease ABC activity
OSK17_15535	COG3118	belongs to the thioredoxin family
OSK17_15545	COG3534	alpha-L-arabinofuranosidase
OSK17_15550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OSK17_15555	COG2086	electron transfer activity
OSK17_15560	COG1024	Enoyl-CoA hydratase
OSK17_15565	COG1309	transcriptional regulator
OSK17_15570	COG0318	PFAM AMP-dependent synthetase and ligase
OSK17_15575	COG3766	membrane
OSK17_15580	COG1193	negative regulation of DNA recombination
OSK17_15585	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OSK17_15585	COG1796	DNA polymerase
OSK17_15590	COG1286	toxin biosynthetic process
OSK17_15595	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OSK17_15600	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OSK17_15605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OSK17_15605	COG0072	phenylalanine-tRNA ligase activity
OSK17_15610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OSK17_15620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OSK17_15630	COG3835	regulator
OSK17_15635	COG0277	FAD linked oxidase domain protein
OSK17_15640	COG0247	lactate metabolic process
OSK17_15645	COG0346	lactoylglutathione lyase activity
OSK17_15655	COG1966	Carbon starvation protein
OSK17_15660	COG3534	alpha-L-arabinofuranosidase
OSK17_15665	COG0395	ABC-type sugar transport system, permease component
OSK17_15670	COG1175	transmembrane transport
OSK17_15675	COG1653	transport
OSK17_15680	COG0371	Dehydrogenase
OSK17_15685	COG0647	UMP catabolic process
OSK17_15690	COG0235	Class ii aldolase
OSK17_15695	COG1069	ribulokinase activity
OSK17_15700	COG2160	L-arabinose isomerase activity
OSK17_15705	COG3507	Belongs to the glycosyl hydrolase 43 family
OSK17_15710	COG1363	Peptidase, m42
OSK17_15720	COG3326	Membrane
OSK17_15725	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OSK17_15730	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OSK17_15735	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OSK17_15745	COG1346	cytolysis
OSK17_15750	COG1380	Effector of murein hydrolase LrgA
OSK17_15755	COG3279	Response regulator of the LytR AlgR family
OSK17_15760	COG3275	phosphorelay sensor kinase activity
OSK17_15765	COG1011	Hydrolase
OSK17_15770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OSK17_15780	COG0398	Pfam SNARE associated Golgi protein
OSK17_15785	COG1484	DNA-dependent DNA replication
OSK17_15790	COG3611	Membrane attachment protein
OSK17_15795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OSK17_15800	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OSK17_15805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OSK17_15810	COG1733	regulation of RNA biosynthetic process
OSK17_15815	COG2814	Major facilitator Superfamily
OSK17_15820	COG0656	L-ascorbic acid biosynthetic process
OSK17_15825	COG0237	dephospho-CoA kinase activity
OSK17_15835	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OSK17_15840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OSK17_15840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OSK17_15845	COG5002	protein histidine kinase activity
OSK17_15850	COG0745	RESPONSE REGULATOR receiver
OSK17_15855	COG0039	L-malate dehydrogenase activity
OSK17_15860	COG0538	isocitrate dehydrogenase activity
OSK17_15865	COG0372	Belongs to the citrate synthase family
OSK17_15870	COG2707	UPF0756 membrane protein
OSK17_15875	COG0628	permease
OSK17_15880	COG3030	protein affecting phage T7 exclusion by the F plasmid
OSK17_15885	COG0469	pyruvate kinase activity
OSK17_15890	COG0205	6-phosphofructokinase activity
OSK17_15895	COG0825	malonyl-CoA metabolic process
OSK17_15900	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OSK17_15905	COG0281	malic enzyme
OSK17_15910	COG0587	DNA-directed DNA polymerase activity
OSK17_15930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OSK17_15940	COG4109	DRTGG domain
OSK17_15945	COG0730	response to heat
OSK17_15950	COG1473	amidohydrolase
OSK17_15955	COG0196	riboflavin kinase activity
OSK17_15960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OSK17_15965	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OSK17_15970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OSK17_15975	COG1126	abc transporter atp-binding protein
OSK17_15980	COG0765	amino acid transport
OSK17_15985	COG0765	amino acid transport
OSK17_15990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSK17_15995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSK17_16000	COG0454	-acetyltransferase
OSK17_16005	COG0583	DNA-binding transcription factor activity
OSK17_16010	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OSK17_16015	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_16025	COG0165	Argininosuccinate lyase
OSK17_16030	COG0137	argininosuccinate synthase activity
OSK17_16035	COG0521	Mo-molybdopterin cofactor biosynthetic process
OSK17_16040	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OSK17_16050	COG0827	DNA restriction-modification system
OSK17_16055	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OSK17_16060	COG3874	Sporulation protein YtfJ
OSK17_16070	COG1714	RDD family
OSK17_16075	COG0616	signal peptide processing
OSK17_16080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OSK17_16085	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OSK17_16090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OSK17_16100	COG0301	tRNA thio-modification
OSK17_16105	COG1104	cysteine desulfurase activity
OSK17_16110	COG1114	Component of the transport system for branched-chain amino acids
OSK17_16115	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OSK17_16120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OSK17_16125	COG1309	transcriptional regulator
OSK17_16130	COG1956	GAF domain-containing protein
OSK17_16135	COG2199	diguanylate cyclase activity
OSK17_16135	COG2203	Gaf domain
OSK17_16140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OSK17_16150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OSK17_16155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OSK17_16160	COG0454	-acetyltransferase
OSK17_16165	COG0517	IMP dehydrogenase activity
OSK17_16170	COG0123	including yeast histone deacetylase and acetoin utilization protein
OSK17_16175	COG1360	Flagellar Motor Protein
OSK17_16180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OSK17_16185	COG1609	Transcriptional regulator
OSK17_16190	COG1605	Chorismate mutase
OSK17_16190	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OSK17_16195	COG3118	belongs to the thioredoxin family
OSK17_16200	COG4980	gas vesicle protein
OSK17_16205	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OSK17_16210	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OSK17_16215	COG1674	ftsk spoiiie
OSK17_16220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OSK17_16225	COG4848	Belongs to the UPF0354 family
OSK17_16230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSK17_16245	COG1363	Peptidase, m42
OSK17_16250	COG5584	Small secreted protein
OSK17_16255	COG0281	malic enzyme
OSK17_16260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSK17_16265	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OSK17_16275	COG0510	thiamine kinase activity
OSK17_16280	COG1523	belongs to the glycosyl hydrolase 13 family
OSK17_16285	COG1597	lipid kinase activity
OSK17_16295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OSK17_16300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OSK17_16305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OSK17_16310	COG2252	PERMEase
OSK17_16315	COG4473	ABC transporter
OSK17_16320	COG1131	(ABC) transporter
OSK17_16325	COG1349	DNA-binding transcription factor activity
OSK17_16330	COG1187	pseudouridine synthase activity
OSK17_16335	COG2244	polysaccharide biosynthetic process
OSK17_16340	COG2081	HI0933 family
OSK17_16345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OSK17_16355	COG5578	integral membrane protein
OSK17_16360	COG0673	inositol 2-dehydrogenase activity
OSK17_16365	COG1653	transport
OSK17_16370	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OSK17_16375	COG4209	transmembrane transport
OSK17_16380	COG2207	Transcriptional regulator
OSK17_16385	COG1653	transport
OSK17_16390	COG0395	ABC-type sugar transport system, permease component
OSK17_16395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OSK17_16400	COG2124	cytochrome p450
OSK17_16405	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OSK17_16415	COG0156	8-amino-7-oxononanoate synthase activity
OSK17_16420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OSK17_16430	COG1073	alpha beta
OSK17_16435	COG1609	Transcriptional regulator
OSK17_16440	COG1653	transport
OSK17_16445	COG1175	transmembrane transport
OSK17_16450	COG0395	ABC-type sugar transport system, permease component
OSK17_16455	COG1486	melibiose metabolic process
OSK17_16460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OSK17_16465	COG0495	leucyl-tRNA aminoacylation
OSK17_16475	COG1366	Belongs to the anti-sigma-factor antagonist family
OSK17_16475	COG2202	Pas domain
OSK17_16480	COG2814	Major facilitator Superfamily
OSK17_16485	COG2433	Pfam Transposase IS66
OSK17_16490	COG0577	efflux transmembrane transporter activity
OSK17_16495	COG1136	(ABC) transporter
OSK17_16500	COG2205	protein histidine kinase activity
OSK17_16505	COG0745	RESPONSE REGULATOR receiver
OSK17_16510	COG0577	efflux transmembrane transporter activity
OSK17_16515	COG1136	(ABC) transporter
OSK17_16530	COG1131	(ABC) transporter
OSK17_16535	COG1725	Transcriptional regulator
OSK17_16550	COG1242	4 iron, 4 sulfur cluster binding
OSK17_16555	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OSK17_16565	COG2267	carboxylic ester hydrolase activity
OSK17_16570	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OSK17_16575	COG1113	amino acid transport
OSK17_16580	COG0367	asparagine synthase
OSK17_16585	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OSK17_16590	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OSK17_16600	COG1506	peptidase
OSK17_16605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OSK17_16610	COG1116	anion transmembrane transporter activity
OSK17_16615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OSK17_16620	COG0494	nUDIX hydrolase
OSK17_16625	COG4824	toxin secretion phage lysis holin
OSK17_16630	COG0783	Belongs to the Dps family
OSK17_16645	COG1854	S-ribosylhomocysteine lyase activity
OSK17_16650	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OSK17_16655	COG0288	reversible hydration of carbon dioxide
OSK17_16660	COG0254	rRNA binding
OSK17_16665	COG1271	oxidase subunit
OSK17_16670	COG1294	oxidase, subunit
OSK17_16680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OSK17_16685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OSK17_16685	COG1321	iron dependent repressor
OSK17_16690	COG1121	(ABC) transporter
OSK17_16695	COG0803	Belongs to the bacterial solute-binding protein 9 family
OSK17_16700	COG4948	Mandelate Racemase Muconate Lactonizing
OSK17_16705	COG0318	PFAM AMP-dependent synthetase and ligase
OSK17_16710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OSK17_16715	COG0596	Alpha beta hydrolase
OSK17_16720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OSK17_16725	COG1169	isochorismate synthase
OSK17_16730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OSK17_16735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OSK17_16740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OSK17_16745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OSK17_16750	COG0438	transferase activity, transferring glycosyl groups
OSK17_16760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OSK17_16765	COG0438	transferase activity, transferring glycosyl groups
OSK17_16770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OSK17_16775	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OSK17_16780	COG0058	SHG alpha-glucan phosphorylase activity
OSK17_16785	COG0297	glycogen (starch) synthase activity
OSK17_16790	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OSK17_16795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OSK17_16800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OSK17_16925	COG3859	Proton-coupled thiamine transporter YuaJ
OSK17_16930	COG1247	-acetyltransferase
OSK17_16935	COG2268	Band 7 protein
OSK17_16940	COG1585	Membrane protein implicated in regulation of membrane protease activity
OSK17_16945	COG2318	DinB family
OSK17_16955	COG1454	alcohol dehydrogenase
OSK17_16960	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_16965	COG1510	regulation of RNA biosynthetic process
OSK17_16975	COG0569	domain protein
OSK17_16980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OSK17_16985	COG4682	membrane
OSK17_16990	COG1705	Flagellar rod assembly protein muramidase FlgJ
OSK17_16995	COG0477	Major facilitator Superfamily
OSK17_17000	COG5553	Cysteine dioxygenase type I
OSK17_17010	COG1968	undecaprenyl-diphosphatase activity
OSK17_17015	COG0628	permease
OSK17_17020	COG0673	inositol 2-dehydrogenase activity
OSK17_17025	COG4806	L-rhamnose isomerase
OSK17_17030	COG3254	rhamnose metabolic process
OSK17_17035	COG1070	Carbohydrate kinase
OSK17_17040	COG1349	DNA-binding transcription factor activity
OSK17_17045	COG3347	Dehydrogenase
OSK17_17045	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_17050	COG0840	transmembrane signaling receptor activity
OSK17_17055	COG0840	transmembrane signaling receptor activity
OSK17_17060	COG0840	transmembrane signaling receptor activity
OSK17_17065	COG0840	transmembrane signaling receptor activity
OSK17_17080	COG0432	Pfam Uncharacterised protein family UPF0047
OSK17_17090	COG0366	Alpha amylase catalytic
OSK17_17095	COG1253	flavin adenine dinucleotide binding
OSK17_17100	COG2738	Putative neutral zinc metallopeptidase
OSK17_17115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OSK17_17130	COG0166	Belongs to the GPI family
OSK17_17135	COG1979	alcohol dehydrogenase
OSK17_17140	COG1979	alcohol dehydrogenase
OSK17_17145	COG2155	Conserved Protein
OSK17_17150	COG1098	S1 RNA binding domain
OSK17_17155	COG0436	Aminotransferase
OSK17_17160	COG1522	sequence-specific DNA binding
OSK17_17165	COG2267	carboxylic ester hydrolase activity
OSK17_17175	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OSK17_17180	COG2205	protein histidine kinase activity
OSK17_17190	COG5018	Exonuclease
OSK17_17200	COG2814	Major facilitator Superfamily
OSK17_17205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OSK17_17210	COG3011	Protein conserved in bacteria
OSK17_17220	COG3290	protein histidine kinase activity
OSK17_17225	COG4565	transcriptional regulatory protein
OSK17_17230	COG1744	ABC transporter substrate-binding protein PnrA-like
OSK17_17235	COG3845	ABC transporter
OSK17_17240	COG4603	Belongs to the binding-protein-dependent transport system permease family
OSK17_17245	COG1079	Belongs to the binding-protein-dependent transport system permease family
OSK17_17250	COG3493	citrate carrier protein
OSK17_17260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OSK17_17260	COG2111	Na H antiporter
OSK17_17265	COG2111	Na H antiporter
OSK17_17270	COG1006	Multisubunit Na H antiporter MnhC subunit
OSK17_17275	COG0651	ATP synthesis coupled electron transport
OSK17_17280	COG1863	multisubunit Na H antiporter MnhE subunit
OSK17_17285	COG2212	antiporter activity
OSK17_17290	COG1320	monovalent cation:proton antiporter activity
OSK17_17295	COG2050	protein possibly involved in aromatic compounds catabolism
OSK17_17300	COG2197	response regulator
OSK17_17305	COG4585	Histidine kinase
OSK17_17315	COG0142	geranyltranstransferase activity
OSK17_17335	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OSK17_17340	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OSK17_17345	COG1335	isochorismatase
OSK17_17350	COG5506	Protein of unknown function (DUF1694)
OSK17_17365	COG0628	permease
OSK17_17380	COG1418	mRNA catabolic process
OSK17_17385	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_17395	COG1511	domain protein
OSK17_17400	COG0433	COG0433 Predicted ATPase
OSK17_17400	COG1674	ftsk spoiiie
OSK17_17405	COG4499	WXG100 protein secretion system (Wss), protein YukC
OSK17_17410	COG5417	Belongs to the EsaB family
OSK17_17415	COG4842	Belongs to the WXG100 family
OSK17_17420	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OSK17_17420	COG2508	Transcriptional regulator
OSK17_17425	COG0686	Belongs to the AlaDH PNT family
OSK17_17430	COG5634	Uncharacterized conserved protein (DUF2278)
OSK17_17435	COG3251	PFAM MbtH domain protein
OSK17_17440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_17445	COG3433	isochorismatase activity
OSK17_17445	COG1535	isochorismatase
OSK17_17450	COG1021	2,3-dihydroxybenzoate-AMP ligase
OSK17_17455	COG1169	isochorismate synthase
OSK17_17460	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_17465	COG2819	hydrolase of the alpha beta superfamily
OSK17_17470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OSK17_17475	COG1268	BioY protein
OSK17_17480	COG2056	Na+-H+ antiporter family
OSK17_17485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OSK17_17490	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
OSK17_17495	COG3584	3D domain protein
OSK17_17510	COG1252	NADH dehydrogenase
OSK17_17515	COG0492	ferredoxin-NADP+ reductase activity
OSK17_17525	COG0516	GMP reductase activity
OSK17_17530	COG2808	Putative FMN-binding domain
OSK17_17535	COG0456	acetyltransferase
OSK17_17540	COG0316	Belongs to the HesB IscA family
OSK17_17545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OSK17_17550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OSK17_17555	COG4844	belongs to the
OSK17_17560	COG1252	NADH dehydrogenase
OSK17_17565	COG4837	Protein of unknown function (DUF1462)
OSK17_17570	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OSK17_17575	COG0823	Involved in the tonB-independent uptake of proteins
OSK17_17575	COG4946	Tricorn protease homolog
OSK17_17575	COG1506	peptidase
OSK17_17580	COG0083	homoserine kinase activity
OSK17_17585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OSK17_17590	COG0460	homoserine dehydrogenase
OSK17_17595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OSK17_17600	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OSK17_17605	COG0647	UMP catabolic process
OSK17_17610	COG2445	Protein of unknown function DUF86
OSK17_17615	COG4470	Protein conserved in bacteria
OSK17_17625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OSK17_17630	COG0739	heme binding
OSK17_17640	COG3377	Domain of unknown function (DUF1805)
OSK17_17645	COG0737	Belongs to the 5'-nucleotidase family
OSK17_17650	COG0730	response to heat
OSK17_17655	COG1801	Protein of unknown function DUF72
OSK17_17665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OSK17_17670	COG2508	Transcriptional regulator
OSK17_17675	COG2233	PERMEase
OSK17_17680	COG2233	PERMEase
OSK17_17685	COG3195	allantoin biosynthetic process
OSK17_17685	COG3648	Uricase
OSK17_17690	COG2351	hydroxyisourate hydrolase activity
OSK17_17700	COG2080	2 iron, 2 sulfur cluster binding
OSK17_17705	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OSK17_17710	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OSK17_17715	COG2068	MobA-Related Protein
OSK17_17720	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OSK17_17725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OSK17_17730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OSK17_17740	COG2356	endonuclease I
OSK17_17745	COG3842	ATPase activity
OSK17_17750	COG2188	Transcriptional regulator
OSK17_17755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OSK17_17760	COG0395	ABC-type sugar transport system, permease component
OSK17_17765	COG1175	transmembrane transport
OSK17_17770	COG1653	transport
OSK17_17775	COG2222	sugar isomerase
OSK17_17780	COG0322	excinuclease ABC activity
OSK17_17785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OSK17_17800	COG0346	lactoylglutathione lyase activity
OSK17_17805	COG0640	Transcriptional regulator
OSK17_17810	COG0719	Fe-S assembly protein
OSK17_17815	COG0822	iron-sulfur transferase activity
OSK17_17820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OSK17_17825	COG0719	Fe-S assembly protein
OSK17_17830	COG0396	ATPase activity
OSK17_17840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OSK17_17845	COG1464	Belongs to the NlpA lipoprotein family
OSK17_17850	COG2011	ABC-type metal ion transport system permease component
OSK17_17855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OSK17_17865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSK17_17870	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OSK17_17880	COG0509	glycine decarboxylation via glycine cleavage system
OSK17_17885	COG1393	Belongs to the ArsC family
OSK17_17890	COG1960	acyl-CoA dehydrogenase activity
OSK17_17895	COG0183	Belongs to the thiolase family
OSK17_17900	COG1024	Enoyl-CoA hydratase
OSK17_17900	COG1250	3-hydroxyacyl-CoA dehydrogenase
OSK17_17910	COG0506	proline dehydrogenase activity
OSK17_17920	COG5577	PFAM Coat F domain
OSK17_17925	COG1846	Transcriptional regulator
OSK17_17930	COG0477	Major facilitator Superfamily
OSK17_17935	COG1942	4-Oxalocrotonate Tautomerase
OSK17_17945	COG0583	DNA-binding transcription factor activity
OSK17_17955	COG1120	ATPase activity
OSK17_17970	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_17975	COG0783	Belongs to the Dps family
OSK17_17980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OSK17_17985	COG0745	RESPONSE REGULATOR receiver
OSK17_17990	COG2770	Histidine kinase
OSK17_17990	COG2205	protein histidine kinase activity
OSK17_18000	COG1309	transcriptional regulator
OSK17_18005	COG0114	fumarate hydratase activity
OSK17_18015	COG0697	spore germination
OSK17_18020	COG0814	amino acid
OSK17_18030	COG2197	response regulator
OSK17_18035	COG4585	Histidine kinase
OSK17_18040	COG4758	membrane
OSK17_18045	COG3595	metallopeptidase activity
OSK17_18050	COG1842	Phage shock protein A
OSK17_18055	COG4758	membrane
OSK17_18060	COG2814	Major facilitator Superfamily
OSK17_18065	COG2096	Adenosyltransferase
OSK17_18070	COG1120	ATPase activity
OSK17_18075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSK17_18080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OSK17_18085	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_18090	COG3386	PFAM SMP-30 Gluconolaconase
OSK17_18095	COG2205	protein histidine kinase activity
OSK17_18100	COG0745	RESPONSE REGULATOR receiver
OSK17_18110	COG1191	sigma factor activity
OSK17_18120	COG2140	Oxalate decarboxylase
OSK17_18130	COG0577	efflux transmembrane transporter activity
OSK17_18135	COG1136	(ABC) transporter
OSK17_18140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OSK17_18145	COG1120	ATPase activity
OSK17_18150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSK17_18155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSK17_18160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OSK17_18165	COG0531	amino acid
OSK17_18175	COG1988	membrane-bound metal-dependent
OSK17_18180	COG1368	sulfuric ester hydrolase activity
OSK17_18185	COG1910	domain protein
OSK17_18190	COG0725	ABC transporter, periplasmic molybdate-binding protein
OSK17_18195	COG4149	molybdate abc transporter
OSK17_18200	COG0656	L-ascorbic acid biosynthetic process
OSK17_18210	COG0025	NhaP-type Na H and K H
OSK17_18215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OSK17_18220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OSK17_18225	COG3973	AAA domain
OSK17_18235	COG2860	membrane
OSK17_18240	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OSK17_18245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OSK17_18250	COG2217	Heavy metal translocating P-type atpase
OSK17_18255	COG2217	Heavy metal translocating P-type atpase
OSK17_18260	COG2608	mercury ion transmembrane transporter activity
OSK17_18265	COG1937	Protein conserved in bacteria
OSK17_18270	COG0673	inositol 2-dehydrogenase activity
OSK17_18275	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OSK17_18280	COG1289	transmembrane transporter activity
OSK17_18290	COG2076	Multidrug Resistance protein
OSK17_18295	COG1309	transcriptional regulator
OSK17_18300	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_18325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OSK17_18330	COG0557	exoribonuclease II activity
OSK17_18335	COG1647	Serine aminopeptidase, S33
OSK17_18340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OSK17_18345	COG0596	Alpha beta hydrolase
OSK17_18350	COG1476	TRANSCRIPTIONal
OSK17_18355	COG1396	sequence-specific DNA binding
OSK17_18360	COG1396	sequence-specific DNA binding
OSK17_18365	COG1733	regulation of RNA biosynthetic process
OSK17_18370	COG0840	transmembrane signaling receptor activity
OSK17_18395	COG1131	(ABC) transporter
OSK17_18425	COG1174	glycine betaine transport
OSK17_18430	COG1732	Glycine betaine
OSK17_18435	COG1174	glycine betaine transport
OSK17_18440	COG1125	glycine betaine transport
OSK17_18440	COG0517	IMP dehydrogenase activity
OSK17_18445	COG1510	regulation of RNA biosynthetic process
OSK17_18450	COG1174	glycine betaine transport
OSK17_18455	COG1732	Glycine betaine
OSK17_18460	COG1174	glycine betaine transport
OSK17_18465	COG1125	glycine betaine transport
OSK17_18465	COG0517	IMP dehydrogenase activity
OSK17_18470	COG1510	regulation of RNA biosynthetic process
OSK17_18475	COG2095	MarC family integral membrane protein
OSK17_18485	COG3064	Membrane
OSK17_18490	COG4640	response to antibiotic
OSK17_18495	COG0456	acetyltransferase
OSK17_18500	COG0148	phosphopyruvate hydratase activity
OSK17_18505	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OSK17_18510	COG0149	triose-phosphate isomerase activity
OSK17_18515	COG0126	phosphoglycerate kinase activity
OSK17_18520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OSK17_18525	COG2390	Transcriptional regulator
OSK17_18530	COG2814	Major facilitator Superfamily
OSK17_18535	COG1609	Transcriptional regulator
OSK17_18540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OSK17_18545	COG0583	DNA-binding transcription factor activity
OSK17_18550	COG0697	spore germination
OSK17_18555	COG1113	amino acid transport
OSK17_18560	COG3858	chitin binding
OSK17_18565	COG1556	Lactate utilization protein
OSK17_18570	COG1139	Iron-sulfur cluster binding protein
OSK17_18575	COG0247	lactate metabolic process
OSK17_18580	COG2197	response regulator
OSK17_18585	COG4585	Histidine kinase
OSK17_18590	COG0842	Transport permease protein
OSK17_18595	COG1131	(ABC) transporter
OSK17_18600	COG0596	Alpha beta hydrolase
OSK17_18605	COG2208	phosphoserine phosphatase activity
OSK17_18610	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OSK17_18615	COG1874	Beta-galactosidase
OSK17_18620	COG3833	ABC-type maltose transport systems, permease component
OSK17_18625	COG1175	transmembrane transport
OSK17_18630	COG2182	Extracellular solute-binding protein
OSK17_18635	COG1609	Transcriptional regulator
OSK17_18640	COG2186	Transcriptional regulator
OSK17_18645	COG1620	l-lactate permease
OSK17_18650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OSK17_18655	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OSK17_18665	COG5039	Polysaccharide pyruvyl transferase
OSK17_18670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OSK17_18675	COG0110	maltose O-acetyltransferase activity
OSK17_18680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OSK17_18685	COG2244	polysaccharide biosynthetic process
OSK17_18690	COG1216	Glycosyl transferase, family 2
OSK17_18695	COG5039	Polysaccharide pyruvyl transferase
OSK17_18700	COG1216	Glycosyl transferase, family 2
OSK17_18710	COG0438	transferase activity, transferring glycosyl groups
OSK17_18715	COG1215	transferase activity, transferring glycosyl groups
OSK17_18720	COG0438	transferase activity, transferring glycosyl groups
OSK17_18725	COG1086	Polysaccharide biosynthesis protein
OSK17_18730	COG0489	protein tyrosine kinase activity
OSK17_18740	COG1396	sequence-specific DNA binding
OSK17_18745	COG2272	Belongs to the type-B carboxylesterase lipase family
OSK17_18755	COG3479	Phenolic acid decarboxylase
OSK17_18765	COG1794	racemase activity, acting on amino acids and derivatives
OSK17_18770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OSK17_18775	COG1621	beta-fructofuranosidase activity
OSK17_18780	COG1621	beta-fructofuranosidase activity
OSK17_18785	COG0531	amino acid
OSK17_18790	COG1309	transcriptional regulator
OSK17_18795	COG2076	Multidrug Resistance protein
OSK17_18800	COG2076	Multidrug Resistance protein
OSK17_18815	COG0740	serine-type endopeptidase activity
OSK17_18820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OSK17_18825	COG0366	Alpha amylase catalytic
OSK17_18830	COG1554	hydrolase, family 65, central catalytic
OSK17_18835	COG5521	maltodextrose utilization protein MalA
OSK17_18840	COG3833	ABC-type maltose transport systems, permease component
OSK17_18845	COG1175	transmembrane transport
OSK17_18850	COG2182	Extracellular solute-binding protein
OSK17_18855	COG0366	Alpha amylase catalytic
OSK17_18860	COG1609	Transcriptional regulator
OSK17_18865	COG1611	Belongs to the LOG family
OSK17_18870	COG1694	Mazg nucleotide pyrophosphohydrolase
OSK17_18875	COG0659	secondary active sulfate transmembrane transporter activity
OSK17_18880	COG0288	reversible hydration of carbon dioxide
OSK17_18885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OSK17_18890	COG0577	efflux transmembrane transporter activity
OSK17_18895	COG1136	(ABC) transporter
OSK17_18900	COG5002	protein histidine kinase activity
OSK17_18905	COG0745	RESPONSE REGULATOR receiver
OSK17_18920	COG2162	N-hydroxyarylamine O-acetyltransferase activity
OSK17_18925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OSK17_18930	COG1481	regulation of sporulation
OSK17_18935	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OSK17_18940	COG1660	Displays ATPase and GTPase activities
OSK17_18945	COG1051	belongs to the nudix hydrolase family
OSK17_18950	COG0492	ferredoxin-NADP+ reductase activity
OSK17_18955	COG3883	PFAM NLP P60 protein
OSK17_18955	COG0791	NLP P60 protein
OSK17_18960	COG0457	Tetratricopeptide repeat
OSK17_18965	COG1132	(ABC) transporter
OSK17_18985	COG0140	phosphoribosyl-ATP diphosphatase activity
OSK17_18985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OSK17_18990	COG0107	imidazoleglycerol-phosphate synthase activity
OSK17_18995	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OSK17_19000	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OSK17_19005	COG0131	Imidazoleglycerol-phosphate dehydratase
OSK17_19010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OSK17_19015	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OSK17_19020	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OSK17_19025	COG4990	cell redox homeostasis
OSK17_19030	COG5297	Belongs to the glycosyl hydrolase family 6
OSK17_19035	COG0110	maltose O-acetyltransferase activity
OSK17_19040	COG0546	phosphoglycolate phosphatase activity
OSK17_19045	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OSK17_19050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OSK17_19055	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OSK17_19060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OSK17_19065	COG0363	glucosamine-6-phosphate deaminase activity
OSK17_19070	COG2188	Transcriptional regulator
OSK17_19075	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OSK17_19080	COG1846	Transcriptional regulator
OSK17_19095	COG1846	Transcriptional regulator
OSK17_19100	COG2814	Major facilitator Superfamily
OSK17_19105	COG1950	PFAM Membrane protein of
OSK17_19110	COG1983	PspC domain protein
OSK17_19115	COG3595	metallopeptidase activity
OSK17_19135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OSK17_19140	COG0556	nucleotide-excision repair
OSK17_19145	COG4897	Protein conserved in bacteria
OSK17_19150	COG3848	Pyruvate phosphate dikinase
OSK17_19150	COG0574	Belongs to the PEP-utilizing enzyme family
OSK17_19155	COG1309	transcriptional regulator
OSK17_19160	COG2814	Major facilitator Superfamily
OSK17_19165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OSK17_19175	COG0793	Belongs to the peptidase S41A family
OSK17_19175	COG3409	Peptidoglycan-binding domain 1 protein
OSK17_19180	COG2177	Part of the ABC transporter FtsEX involved in
OSK17_19185	COG2884	Cell division ATP-binding protein ftsE
OSK17_19190	COG2010	Cytochrome c
OSK17_19195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OSK17_19205	COG0653	protein targeting
OSK17_19210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OSK17_19225	COG1516	flagellar protein fliS
OSK17_19230	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OSK17_19235	COG1334	flagellar protein FlaG
OSK17_19240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OSK17_19245	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OSK17_19250	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OSK17_19260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OSK17_19265	COG4786	Flagellar basal body rod
OSK17_19265	COG1256	bacterial-type flagellum assembly
OSK17_19270	COG3418	PFAM FlgN family protein
OSK17_19275	COG2747	anti-sigma28 factor FlgM
OSK17_19285	COG1040	competence protein
OSK17_19295	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OSK17_19300	COG1307	EDD domain protein, DegV family
OSK17_19305	COG2197	response regulator
OSK17_19310	COG4585	Histidine kinase
OSK17_19315	COG1739	Uncharacterized protein family UPF0029
OSK17_19320	COG1316	TRANSCRIPTIONal
OSK17_19325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OSK17_19330	COG0438	transferase activity, transferring glycosyl groups
OSK17_19335	COG1215	transferase activity, transferring glycosyl groups
OSK17_19340	COG3206	protein involved in exopolysaccharide biosynthesis
OSK17_19345	COG3307	-O-antigen
OSK17_19350	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OSK17_19355	COG0297	glycogen (starch) synthase activity
OSK17_19355	COG0438	transferase activity, transferring glycosyl groups
OSK17_19360	COG2244	polysaccharide biosynthetic process
OSK17_19375	COG2247	cell wall binding repeat
OSK17_19375	COG0860	N-Acetylmuramoyl-L-alanine amidase
OSK17_19380	COG2385	sporulation resulting in formation of a cellular spore
OSK17_19380	COG2247	cell wall binding repeat
OSK17_19390	COG1316	TRANSCRIPTIONal
OSK17_19395	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OSK17_19415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OSK17_19420	COG1134	teichoic acid transport
OSK17_19425	COG1682	transport, permease protein
OSK17_19430	COG1215	transferase activity, transferring glycosyl groups
OSK17_19430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OSK17_19435	COG0463	Glycosyl transferase, family 2
OSK17_19480	COG4193	domain, Protein
OSK17_19485	COG1482	cell wall glycoprotein biosynthetic process
OSK17_19490	COG0697	spore germination
OSK17_19495	COG0814	amino acid
OSK17_19505	COG2814	Major facilitator Superfamily
OSK17_19510	COG1316	TRANSCRIPTIONal
OSK17_19515	COG0561	phosphatase activity
OSK17_19520	COG0791	NLP P60 protein
OSK17_19530	COG2843	Capsule synthesis protein
OSK17_19540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OSK17_19545	COG1609	Transcriptional regulator
OSK17_19550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OSK17_19555	COG1869	D-ribose catabolic process
OSK17_19560	COG1129	ABC transporter
OSK17_19565	COG1172	Belongs to the binding-protein-dependent transport system permease family
OSK17_19570	COG1879	ABC-type sugar transport system periplasmic component
OSK17_19575	COG3103	Sh3 type 3 domain protein
OSK17_19585	COG2249	NAD(P)H dehydrogenase (quinone) activity
OSK17_19590	COG3527	Alpha-acetolactate decarboxylase
OSK17_19595	COG0028	Belongs to the TPP enzyme family
OSK17_19600	COG0583	DNA-binding transcription factor activity
OSK17_19605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OSK17_19620	COG5337	Spore coat protein CotH
OSK17_19630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OSK17_19640	COG0405	Gamma-glutamyltransferase
OSK17_19645	COG1522	sequence-specific DNA binding
OSK17_19650	COG2059	Chromate
OSK17_19655	COG2059	Chromate
OSK17_19670	COG5444	nuclease activity
OSK17_19690	COG3878	Protein conserved in bacteria
OSK17_19695	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OSK17_19700	COG4464	protein tyrosine phosphatase activity
OSK17_19705	COG0489	protein tyrosine kinase activity
OSK17_19710	COG3944	biosynthesis protein
OSK17_19720	COG4715	Zinc finger, swim domain protein
OSK17_19725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OSK17_19730	COG0561	phosphatase activity
OSK17_19735	COG1349	DNA-binding transcription factor activity
OSK17_19740	COG0629	single-stranded DNA binding
OSK17_19755	COG3764	Sortase (surface protein transpeptidase)
OSK17_19765	COG3279	Response regulator of the LytR AlgR family
OSK17_19775	COG2972	Histidine kinase
OSK17_19775	COG0745	RESPONSE REGULATOR receiver
OSK17_19780	COG1970	mechanosensitive ion channel activity
OSK17_19785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OSK17_19790	COG0457	Tetratricopeptide repeat
OSK17_19795	COG4786	Flagellar basal body rod
OSK17_19800	COG4786	Flagellar basal body rod
OSK17_19805	COG1077	Cell shape determining protein MreB Mrl
OSK17_19810	COG1609	Transcriptional regulator
OSK17_19820	COG1846	Transcriptional regulator
OSK17_19825	COG2814	Major facilitator Superfamily
OSK17_19830	COG3420	alginic acid biosynthetic process
OSK17_19835	COG1953	Uracil, thiamine, allantoin
OSK17_19840	COG0477	Major facilitator Superfamily
OSK17_19845	COG1335	isochorismatase
OSK17_19855	COG0004	ammonium transporteR
OSK17_19860	COG0347	Belongs to the P(II) protein family
OSK17_19865	COG0671	phosphoesterase, PA-phosphatase related
OSK17_19875	COG0739	heme binding
OSK17_19880	COG1247	-acetyltransferase
OSK17_19900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OSK17_19905	COG0789	Transcriptional regulator
OSK17_19915	COG2910	NAD(P)H-binding
OSK17_19920	COG1959	2 iron, 2 sulfur cluster binding
OSK17_19925	COG0804	urea catabolic process
OSK17_19930	COG0832	Belongs to the urease beta subunit family
OSK17_19935	COG0831	urea catabolic process
OSK17_19950	COG3237	CsbD-like
OSK17_19955	COG1994	Peptidase M50
OSK17_19960	COG0457	Tetratricopeptide repeat
OSK17_19965	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OSK17_19970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OSK17_19980	COG2304	oxidoreductase activity
OSK17_19990	COG2304	oxidoreductase activity
OSK17_19995	COG2385	sporulation resulting in formation of a cellular spore
OSK17_20000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OSK17_20010	COG4836	Membrane
OSK17_20020	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OSK17_20025	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OSK17_20030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OSK17_20035	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OSK17_20040	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OSK17_20045	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OSK17_20055	COG0356	it plays a direct role in the translocation of protons across the membrane
OSK17_20065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OSK17_20070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OSK17_20075	COG4475	Protein of unknown function (DUF436)
OSK17_20080	COG0698	ribose 5-phosphate isomerase
OSK17_20085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OSK17_20090	COG1971	Probably functions as a manganese efflux pump
OSK17_20095	COG0009	L-threonylcarbamoyladenylate synthase
OSK17_20100	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OSK17_20120	COG2890	protein-(glutamine-N5) methyltransferase activity
OSK17_20125	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OSK17_20130	COG0346	lactoylglutathione lyase activity
OSK17_20135	COG0789	Transcriptional regulator
OSK17_20140	COG0679	Auxin Efflux Carrier
OSK17_20145	COG0281	malic enzyme
OSK17_20150	COG1435	thymidine kinase activity
OSK17_20160	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OSK17_20170	COG1494	fructose-1,6-bisphosphatase
OSK17_20175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OSK17_20180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OSK17_20185	COG0191	fructose-bisphosphate aldolase activity
OSK17_20190	COG2204	response regulator
OSK17_20195	COG4821	SIS domain
OSK17_20200	COG0504	CTP synthase activity
OSK17_20205	COG3343	RNA polymerase activity
OSK17_20210	COG1960	acyl-CoA dehydrogenase activity
OSK17_20215	COG2181	nitrate reductase activity
OSK17_20215	COG0247	lactate metabolic process
OSK17_20220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OSK17_20225	COG4294	response to UV
OSK17_20235	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OSK17_20240	COG1132	(ABC) transporter
OSK17_20245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OSK17_20255	COG2181	nitrate reductase activity
OSK17_20260	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OSK17_20265	COG1140	nitrate reductase beta subunit
OSK17_20270	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OSK17_20275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OSK17_20285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OSK17_20290	COG2223	nitrite transmembrane transporter activity
OSK17_20295	COG0018	arginyl-trna synthetase
OSK17_20300	COG4506	Protein conserved in bacteria
OSK17_20315	COG0535	radical SAM domain protein
OSK17_20325	COG1131	(ABC) transporter
OSK17_20330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OSK17_20335	COG0612	Peptidase, M16
OSK17_20340	COG0612	Peptidase, M16
OSK17_20350	COG3391	amine dehydrogenase activity
OSK17_20355	COG3391	amine dehydrogenase activity
OSK17_20360	COG0457	Tetratricopeptide repeat
OSK17_20390	COG1131	(ABC) transporter
OSK17_20400	COG0010	Belongs to the arginase family
OSK17_20405	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OSK17_20410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OSK17_20425	COG1994	Peptidase M50
OSK17_20430	COG1942	4-Oxalocrotonate Tautomerase
OSK17_20435	COG1846	Transcriptional regulator
OSK17_20440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OSK17_20445	COG0477	Major facilitator Superfamily
OSK17_20450	COG1959	2 iron, 2 sulfur cluster binding
OSK17_20455	COG3465	dGTPase activity
OSK17_20460	COG1078	dGTPase activity
OSK17_20465	COG4844	belongs to the
OSK17_20475	COG0697	spore germination
OSK17_20480	COG0095	Lipoate-protein ligase
OSK17_20485	COG0583	DNA-binding transcription factor activity
OSK17_20490	COG0280	phosphate acetyltransferase
OSK17_20495	COG3253	May function as heme-dependent peroxidase
OSK17_20500	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_20505	COG0436	Aminotransferase
OSK17_20510	COG2814	Major facilitator Superfamily
OSK17_20515	COG0151	Belongs to the GarS family
OSK17_20520	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_20525	COG1917	Cupin 2, conserved barrel domain protein
OSK17_20530	COG0077	Prephenate dehydratase
OSK17_20535	COG2814	Major facilitator Superfamily
OSK17_20540	COG0833	amino acid
OSK17_20545	COG4187	Peptidase family M20/M25/M40
OSK17_20550	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_20555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OSK17_20565	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
OSK17_20570	COG1091	dTDP-4-dehydrorhamnose reductase activity
OSK17_20575	COG1088	dTDP-glucose 4,6-dehydratase activity
OSK17_20580	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OSK17_20585	COG3980	spore coat polysaccharide biosynthesis protein
OSK17_20590	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
OSK17_20595	COG2089	acid synthase
OSK17_20600	COG0456	acetyltransferase
OSK17_20605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OSK17_20610	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OSK17_20615	COG0463	Glycosyl transferase, family 2
OSK17_20625	COG2363	Small membrane protein
OSK17_20630	COG2233	PERMEase
OSK17_20640	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_20645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OSK17_20650	COG1216	Glycosyl transferase, family 2
OSK17_20665	COG1695	Transcriptional regulator
OSK17_20670	COG0351	phosphomethylpyrimidine kinase
OSK17_20680	COG1621	beta-fructofuranosidase activity
OSK17_20685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_20685	COG1263	PTS System
OSK17_20690	COG2116	formate transmembrane transporter activity
OSK17_20695	COG3711	transcriptional antiterminator
OSK17_20705	COG1404	Belongs to the peptidase S8 family
OSK17_20710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OSK17_20715	COG0778	Nitroreductase
OSK17_20720	COG0772	Belongs to the SEDS family
OSK17_20730	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OSK17_20735	COG1845	cytochrome c oxidase, subunit III
OSK17_20740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OSK17_20745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OSK17_20750	COG2261	transglycosylase associated protein
OSK17_20755	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OSK17_20760	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OSK17_20765	COG2246	polysaccharide biosynthetic process
OSK17_20770	COG1309	transcriptional regulator
OSK17_20780	COG3162	membrane
OSK17_20785	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OSK17_20790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OSK17_20795	COG2837	iron assimilation
OSK17_20800	COG2822	iron ion transport
OSK17_20805	COG0672	)-iron permease
OSK17_20810	COG0352	thiamine-phosphate diphosphorylase activity
OSK17_20815	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OSK17_20820	COG0583	DNA-binding transcription factor activity
OSK17_20825	COG1380	Effector of murein hydrolase LrgA
OSK17_20830	COG1346	cytolysis
OSK17_20835	COG2814	Major facilitator Superfamily
OSK17_20840	COG4895	conserved protein (DUF2196)
OSK17_20845	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OSK17_20850	COG0346	lactoylglutathione lyase activity
OSK17_20875	COG1404	Belongs to the peptidase S8 family
OSK17_20880	COG1263	PTS System
OSK17_20880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_20885	COG3711	transcriptional antiterminator
OSK17_20890	COG1442	glycosyl transferase family 8
OSK17_20895	COG5522	Integral membrane protein (intg_mem_TP0381)
OSK17_20900	COG1846	Transcriptional regulator
OSK17_20905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OSK17_20910	COG2234	aminopeptidase activity
OSK17_20925	COG2814	Major facilitator Superfamily
OSK17_20930	COG2357	RelA SpoT domain protein
OSK17_20935	COG1575	Belongs to the MenA family. Type 1 subfamily
OSK17_20950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OSK17_20955	COG1696	Membrane protein involved in D-alanine export
OSK17_20960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSK17_20965	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OSK17_20970	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
OSK17_20975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OSK17_20980	COG1486	melibiose metabolic process
OSK17_20985	COG1447	Phosphotransferase system cellobiose-specific component IIA
OSK17_20990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OSK17_20995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OSK17_21000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OSK17_21000	COG3711	transcriptional antiterminator
OSK17_21010	COG2094	Belongs to the DNA glycosylase MPG family
OSK17_21015	COG0753	catalase activity
OSK17_21020	COG2814	Major facilitator Superfamily
OSK17_21025	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OSK17_21030	COG1131	(ABC) transporter
OSK17_21050	COG1595	DNA-templated transcription, initiation
OSK17_21055	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OSK17_21060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OSK17_21065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OSK17_21070	COG4988	ABC transporter
OSK17_21075	COG1294	oxidase, subunit
OSK17_21080	COG1271	oxidase subunit
OSK17_21085	COG3493	citrate carrier protein
OSK17_21090	COG0501	Belongs to the peptidase M48B family
OSK17_21100	COG0726	polysaccharide deacetylase
OSK17_21115	COG3842	ATPase activity
OSK17_21120	COG2508	Transcriptional regulator
OSK17_21125	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_21130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OSK17_21140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OSK17_21145	COG1881	PFAM PEBP family protein
OSK17_21150	COG0583	DNA-binding transcription factor activity
OSK17_21160	COG4585	Histidine kinase
OSK17_21165	COG2197	response regulator
OSK17_21170	COG2195	Cleaves the N-terminal amino acid of tripeptides
OSK17_21185	COG4894	glucomannan catabolic process
OSK17_21190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OSK17_21195	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OSK17_21200	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_21205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OSK17_21210	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OSK17_21215	COG2610	gluconate transmembrane transporter activity
OSK17_21220	COG0500	methyltransferase
OSK17_21225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OSK17_21240	COG0693	protein deglycase activity
OSK17_21240	COG0753	catalase activity
OSK17_21245	COG2851	Citrate transporter
OSK17_21250	COG2273	Hydrolase Family 16
OSK17_21255	COG3711	transcriptional antiterminator
OSK17_21265	COG2270	Major facilitator Superfamily
OSK17_21270	COG0513	Belongs to the DEAD box helicase family
OSK17_21275	COG2755	lipolytic protein G-D-S-L family
OSK17_21275	COG3401	FG-GAP repeat protein
OSK17_21320	COG3209	COG3209 Rhs family protein
OSK17_21325	COG0697	spore germination
OSK17_21330	COG0589	response to stress
OSK17_21335	COG2723	6-phospho-beta-galactosidase activity
OSK17_21340	COG1263	PTS System
OSK17_21340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_21340	COG2190	(PTS) system
OSK17_21385	COG3507	Belongs to the glycosyl hydrolase 43 family
OSK17_21400	COG2986	histidine ammonia-lyase
OSK17_21405	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OSK17_21410	COG1228	amidohydrolase
OSK17_21415	COG0010	Belongs to the arginase family
OSK17_21420	COG0833	amino acid
OSK17_21425	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OSK17_21430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OSK17_21435	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OSK17_21440	COG2390	Transcriptional regulator
OSK17_21450	COG3192	ethanolamine utilization protein
OSK17_21455	COG2079	MmgE PrpD family protein
OSK17_21460	COG1473	amidohydrolase
OSK17_21465	COG1126	abc transporter atp-binding protein
OSK17_21470	COG0765	amino acid transport
OSK17_21475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSK17_21480	COG0456	acetyltransferase
OSK17_21485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OSK17_21490	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
OSK17_21495	COG0561	phosphatase activity
OSK17_21525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OSK17_21530	COG5294	Protein conserved in bacteria
OSK17_21535	COG0577	efflux transmembrane transporter activity
OSK17_21540	COG1136	(ABC) transporter
OSK17_21545	COG2205	protein histidine kinase activity
OSK17_21550	COG0745	RESPONSE REGULATOR receiver
OSK17_21555	COG0191	fructose-bisphosphate aldolase activity
OSK17_21560	COG1082	Xylose isomerase domain protein TIM barrel
OSK17_21565	COG1082	Xylose isomerase domain protein TIM barrel
OSK17_21570	COG0673	inositol 2-dehydrogenase activity
OSK17_21575	COG2814	Major facilitator Superfamily
OSK17_21580	COG1082	Xylose isomerase domain protein TIM barrel
OSK17_21585	COG3962	Belongs to the TPP enzyme family
OSK17_21590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OSK17_21600	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_21605	COG1349	DNA-binding transcription factor activity
OSK17_21610	COG0667	Aldo Keto reductase
OSK17_21625	COG2814	Major facilitator Superfamily
OSK17_21630	COG0326	Molecular chaperone. Has ATPase activity
OSK17_21640	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_21665	COG1309	transcriptional regulator
OSK17_21670	COG1012	belongs to the aldehyde dehydrogenase family
OSK17_21675	COG1714	RDD family
OSK17_21680	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OSK17_21690	COG1714	RDD family
OSK17_21695	COG2311	Membrane
OSK17_21700	COG1917	Cupin 2, conserved barrel domain protein
OSK17_21705	COG1309	transcriptional regulator
OSK17_21710	COG1028	Short-chain dehydrogenase reductase Sdr
OSK17_21715	COG1846	Transcriptional regulator
OSK17_21720	COG1380	Effector of murein hydrolase LrgA
OSK17_21725	COG1346	cytolysis
OSK17_21730	COG5039	Polysaccharide pyruvyl transferase
OSK17_21735	COG1929	Belongs to the glycerate kinase type-1 family
OSK17_21740	COG1802	Transcriptional regulator
OSK17_21745	COG1070	Carbohydrate kinase
OSK17_21750	COG2610	gluconate transmembrane transporter activity
OSK17_21755	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OSK17_21760	COG0450	alkyl hydroperoxide reductase
OSK17_21765	COG3634	alkyl hydroperoxide reductase activity
OSK17_21785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OSK17_21785	COG1263	PTS System
OSK17_21790	COG2188	Transcriptional regulator
OSK17_21805	COG1131	(ABC) transporter
OSK17_21810	COG1994	Peptidase M50
OSK17_21815	COG0535	radical SAM domain protein
OSK17_21825	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
OSK17_21835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OSK17_21850	COG1063	alcohol dehydrogenase
OSK17_21870	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OSK17_21875	COG0456	acetyltransferase
OSK17_21880	COG0457	Tetratricopeptide repeat
OSK17_21890	COG0010	Belongs to the arginase family
OSK17_21895	COG0833	amino acid
OSK17_21900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OSK17_21905	COG3829	transcription factor binding
OSK17_21920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OSK17_21925	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OSK17_21930	COG4853	Protein conserved in bacteria
OSK17_21935	COG4863	YycH protein
OSK17_21940	COG5002	protein histidine kinase activity
OSK17_21945	COG0745	RESPONSE REGULATOR receiver
OSK17_21975	COG0346	lactoylglutathione lyase activity
OSK17_21980	COG0305	Participates in initiation and elongation during chromosome replication
OSK17_21995	COG3093	addiction module antidote protein HigA
OSK17_22000	COG2807	transmembrane transport
OSK17_22005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OSK17_22010	COG0359	binds to the 23S rRNA
OSK17_22015	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OSK17_22020	COG4241	membrane
OSK17_22030	COG5577	PFAM Coat F domain
OSK17_22035	COG1733	regulation of RNA biosynthetic process
OSK17_22040	COG1227	inorganic diphosphatase activity
OSK17_22055	COG2271	Major facilitator Superfamily
OSK17_22060	COG0789	Transcriptional regulator
OSK17_22060	COG4978	Transcriptional regulator
OSK17_22080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSK17_22085	COG1846	Transcriptional regulator
OSK17_22090	COG2153	protein acetylation
OSK17_22095	COG2364	Membrane
OSK17_22100	COG0456	acetyltransferase
OSK17_22105	COG2315	Protein conserved in bacteria
OSK17_22110	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OSK17_22120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OSK17_22125	COG0798	PFAM Bile acid sodium symporter
OSK17_22130	COG0346	lactoylglutathione lyase activity
OSK17_22135	COG0640	Transcriptional regulator
OSK17_22160	COG0741	lytic transglycosylase activity
OSK17_22160	COG0791	NLP P60 protein
OSK17_22165	COG5644	endopeptidase inhibitor activity
OSK17_22175	COG0433	COG0433 Predicted ATPase
OSK17_22210	COG2946	Replication initiation factor
OSK17_22215	COG1674	ftsk spoiiie
OSK17_22245	COG1396	sequence-specific DNA binding
OSK17_22250	COG2856	Zn peptidase
OSK17_22255	COG0457	Tetratricopeptide repeat
OSK17_22275	COG1266	CAAX protease self-immunity
OSK17_22280	COG0477	Major facilitator Superfamily
OSK17_22280	COG2814	Major facilitator Superfamily
OSK17_22285	COG0110	maltose O-acetyltransferase activity
OSK17_22290	COG0346	lactoylglutathione lyase activity
OSK17_22295	COG1609	Transcriptional regulator
OSK17_22300	COG0708	Exodeoxyribonuclease III
OSK17_22305	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OSK17_22310	COG0629	single-stranded DNA binding
OSK17_22315	COG0360	Binds together with S18 to 16S ribosomal RNA
OSK17_22320	COG0012	GTP binding
OSK17_22325	COG0243	molybdopterin cofactor binding
OSK17_22330	COG4481	Protein conserved in bacteria
OSK17_22335	COG3949	Membrane
OSK17_22345	COG1475	DNA binding
OSK17_22350	COG1192	Involved in chromosome partitioning
OSK17_22360	COG1475	DNA binding
OSK17_22365	COG0357	Ribosomal RNA small subunit methyltransferase G
OSK17_22370	COG0445	tRNA wobble uridine modification
OSK17_22375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OSK17_22380	COG1847	R3H domain protein
OSK17_22385	COG0706	membrane insertase activity
OSK17_22390	COG0594	ribonuclease P activity