locus-tag	class	description
D3Z87_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D3Z87_00010	COG0592	DNA-directed DNA polymerase activity
D3Z87_00015	COG2501	S4 domain
D3Z87_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D3Z87_00030	COG0187	DNA topoisomerase II activity
D3Z87_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3Z87_00070	COG0517	IMP dehydrogenase activity
D3Z87_00070	COG0516	GMP reductase activity
D3Z87_00075	COG1686	Belongs to the peptidase S11 family
D3Z87_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D3Z87_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D3Z87_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D3Z87_00100	COG1428	Deoxynucleoside kinase
D3Z87_00105	COG1428	Deoxynucleoside kinase
D3Z87_00110	COG3858	chitin binding
D3Z87_00110	COG1388	LysM domain
D3Z87_00115	COG1335	isochorismatase
D3Z87_00120	COG0590	tRNA wobble adenosine to inosine editing
D3Z87_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D3Z87_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D3Z87_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D3Z87_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D3Z87_00190	COG3853	Toxic anion resistance protein (TelA)
D3Z87_00195	COG1982	Orn Lys Arg decarboxylase major
D3Z87_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3Z87_00205	COG3870	Protein conserved in bacteria
D3Z87_00210	COG1728	Protein conserved in bacteria
D3Z87_00215	COG0470	DNA polymerase III
D3Z87_00220	COG1774	PSP1 C-terminal conserved region
D3Z87_00225	COG4467	Involved in initiation control of chromosome replication
D3Z87_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D3Z87_00235	COG2827	Endonuclease containing a URI domain
D3Z87_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D3Z87_00245	COG2002	toxin-antitoxin pair type II binding
D3Z87_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3Z87_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3Z87_00255	COG0084	hydrolase, TatD family'
D3Z87_00260	COG3584	3D domain protein
D3Z87_00260	COG3583	domain protein
D3Z87_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D3Z87_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D3Z87_00280	COG4466	Protein conserved in bacteria
D3Z87_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D3Z87_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3Z87_00300	COG0251	oxidation-reduction process
D3Z87_00305	COG2088	sporulation resulting in formation of a cellular spore
D3Z87_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D3Z87_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D3Z87_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D3Z87_00325	COG0193	aminoacyl-tRNA hydrolase activity
D3Z87_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D3Z87_00340	COG2002	toxin-antitoxin pair type II binding
D3Z87_00345	COG2244	polysaccharide biosynthetic process
D3Z87_00350	COG3956	TIGRFAM MazG family protein
D3Z87_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D3Z87_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D3Z87_00375	COG1098	S1 RNA binding domain
D3Z87_00390	COG2208	phosphoserine phosphatase activity
D3Z87_00395	COG2304	oxidoreductase activity
D3Z87_00400	COG0515	serine threonine protein kinase
D3Z87_00405	COG0037	tRNA processing
D3Z87_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3Z87_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D3Z87_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D3Z87_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3Z87_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3Z87_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3Z87_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
D3Z87_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3Z87_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D3Z87_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D3Z87_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D3Z87_00470	COG1396	sequence-specific DNA binding
D3Z87_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3Z87_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D3Z87_00500	COG4463	regulation of RNA biosynthetic process
D3Z87_00505	COG3880	PFAM UvrB UvrC protein
D3Z87_00510	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D3Z87_00515	COG0542	response to heat
D3Z87_00520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D3Z87_00525	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D3Z87_00530	COG4956	integral membrane protein (PIN domain superfamily)
D3Z87_00535	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D3Z87_00540	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D3Z87_00545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D3Z87_00560	COG0215	cysteine-tRNA ligase activity
D3Z87_00565	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D3Z87_00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3Z87_00575	COG3688	RNA-binding protein containing a PIN domain
D3Z87_00580	COG1595	DNA-templated transcription, initiation
D3Z87_00585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3Z87_00590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D3Z87_00595	COG0250	Participates in transcription elongation, termination and antitermination
D3Z87_00600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D3Z87_00605	COG0081	regulation of translation
D3Z87_00610	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D3Z87_00615	COG0222	ribosome binding
D3Z87_00620	COG2813	Specifically methylates the guanine in position
D3Z87_00625	COG0085	RNA polymerase activity
D3Z87_00630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D3Z87_00635	COG1358	cellular component organization or biogenesis
D3Z87_00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D3Z87_00645	COG0049	tRNA binding
D3Z87_00650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D3Z87_00655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D3Z87_00660	COG0596	Alpha beta hydrolase
D3Z87_00665	COG0051	transcription antitermination factor activity, RNA binding
D3Z87_00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D3Z87_00675	COG0088	Forms part of the polypeptide exit tunnel
D3Z87_00680	COG0089	rRNA binding
D3Z87_00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D3Z87_00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D3Z87_00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D3Z87_00700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D3Z87_00705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D3Z87_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
D3Z87_00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D3Z87_00720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D3Z87_00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D3Z87_00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D3Z87_00745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D3Z87_00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D3Z87_00755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D3Z87_00760	COG1841	ribosomal large subunit assembly
D3Z87_00765	COG0200	Binds to the 23S rRNA
D3Z87_00770	COG0201	protein transport
D3Z87_00775	COG0563	adenylate kinase activity
D3Z87_00780	COG0024	Methionine aminopeptidase
D3Z87_00785	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D3Z87_00790	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D3Z87_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D3Z87_00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D3Z87_00805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D3Z87_00810	COG0202	RNA polymerase activity
D3Z87_00815	COG0203	ribosomal protein L17
D3Z87_00820	COG1122	ATPase activity
D3Z87_00825	COG1122	ATPase activity
D3Z87_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D3Z87_00835	COG0101	tRNA pseudouridine synthase activity
D3Z87_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D3Z87_00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D3Z87_00850	COG2226	methyltransferase
D3Z87_00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z87_00865	COG0489	protein tyrosine kinase activity
D3Z87_00875	COG2194	sulfuric ester hydrolase activity
D3Z87_00880	COG0726	polysaccharide deacetylase
D3Z87_00965	COG0659	secondary active sulfate transmembrane transporter activity
D3Z87_00970	COG0385	Bile acid
D3Z87_00975	COG2819	hydrolase of the alpha beta superfamily
D3Z87_00980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z87_00985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z87_00990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z87_00995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z87_00995	COG2207	Transcriptional regulator
D3Z87_01000	COG3876	Protein conserved in bacteria
D3Z87_01005	COG1472	Belongs to the glycosyl hydrolase 3 family
D3Z87_01010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3Z87_01015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_01015	COG1263	PTS System
D3Z87_01020	COG1737	Transcriptional regulator
D3Z87_01025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D3Z87_01030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z87_01035	COG1683	Conserved Protein
D3Z87_01065	COG1595	DNA-templated transcription, initiation
D3Z87_01070	COG5662	AntiSigma factor
D3Z87_01075	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D3Z87_01080	COG4856	YbbR-like protein
D3Z87_01085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3Z87_01090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D3Z87_01100	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D3Z87_01105	COG2169	Transcriptional regulator
D3Z87_01110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3Z87_01115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3Z87_01120	COG3002	Belongs to the UPF0753 family
D3Z87_01125	COG0288	reversible hydration of carbon dioxide
D3Z87_01135	COG5609	conserved protein (DUF2294)
D3Z87_01140	COG0640	Transcriptional regulator
D3Z87_01145	COG2814	Major facilitator Superfamily
D3Z87_01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D3Z87_01160	COG0535	radical SAM domain protein
D3Z87_01165	COG1266	CAAX protease self-immunity
D3Z87_01170	COG1131	(ABC) transporter
D3Z87_01180	COG1413	lyase activity
D3Z87_01185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_01190	COG0596	Alpha beta hydrolase
D3Z87_01195	COG0745	RESPONSE REGULATOR receiver
D3Z87_01200	COG0642	Histidine kinase
D3Z87_01210	COG0515	serine threonine protein kinase
D3Z87_01225	COG1113	amino acid transport
D3Z87_01240	COG2602	Beta-lactamase
D3Z87_01245	COG2124	cytochrome p450
D3Z87_01260	COG0584	glycerophosphoryl diester phosphodiesterase
D3Z87_01265	COG2271	Major facilitator Superfamily
D3Z87_01280	COG1846	Transcriptional regulator
D3Z87_01280	COG0456	acetyltransferase
D3Z87_01285	COG2271	Major facilitator Superfamily
D3Z87_01300	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_01305	COG0697	spore germination
D3Z87_01310	COG2207	Transcriptional regulator
D3Z87_01310	COG1917	Cupin 2, conserved barrel domain protein
D3Z87_01330	COG0596	Alpha beta hydrolase
D3Z87_01335	COG1183	phosphatidylcholine synthase activity
D3Z87_01340	COG0586	Pfam SNARE associated Golgi protein
D3Z87_01345	COG0688	phosphatidylethanolamine metabolic process
D3Z87_01355	COG2312	Erythromycin esterase
D3Z87_01360	COG2207	Transcriptional regulator
D3Z87_01370	COG1301	dicarboxylic acid transport
D3Z87_01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_01375	COG1263	PTS System
D3Z87_01375	COG2190	(PTS) system
D3Z87_01380	COG0363	glucosamine-6-phosphate deaminase activity
D3Z87_01395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3Z87_01400	COG0833	amino acid
D3Z87_01405	COG2040	homocysteine
D3Z87_01415	COG1115	amino acid carrier protein
D3Z87_01420	COG2066	Belongs to the glutaminase family
D3Z87_01425	COG4191	Histidine kinase
D3Z87_01430	COG0784	Response regulator, receiver
D3Z87_01440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3Z87_01445	COG1012	belongs to the aldehyde dehydrogenase family
D3Z87_01450	COG2271	Major facilitator Superfamily
D3Z87_01455	COG4948	Mandelate Racemase Muconate Lactonizing
D3Z87_01460	COG2186	Transcriptional regulator
D3Z87_01465	COG2721	sulfolactate sulfo-lyase activity
D3Z87_01470	COG3173	Aminoglycoside phosphotransferase
D3Z87_01480	COG0697	spore germination
D3Z87_01485	COG0745	RESPONSE REGULATOR receiver
D3Z87_01490	COG2205	protein histidine kinase activity
D3Z87_01495	COG1131	(ABC) transporter
D3Z87_01510	COG3773	Cell wall hydrolase
D3Z87_01515	COG2304	oxidoreductase activity
D3Z87_01525	COG3540	Alkaline phosphatase
D3Z87_01530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3Z87_01535	COG0805	protein transport
D3Z87_01540	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D3Z87_01545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3Z87_01550	COG0477	Major facilitator Superfamily
D3Z87_01555	COG1309	transcriptional regulator
D3Z87_01560	COG0252	asparaginase activity
D3Z87_01565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D3Z87_01570	COG1714	RDD family
D3Z87_01575	COG1405	negative regulation of cell septum assembly
D3Z87_01575	COG3012	SEC-C Motif Domain Protein
D3Z87_01580	COG3290	protein histidine kinase activity
D3Z87_01585	COG3279	Response regulator of the LytR AlgR family
D3Z87_01590	COG4555	ABC transporter
D3Z87_01595	COG1668	transmembrane transport
D3Z87_01600	COG0667	Aldo Keto reductase
D3Z87_01610	COG1595	DNA-templated transcription, initiation
D3Z87_01615	COG1595	DNA-templated transcription, initiation
D3Z87_01620	COG1876	peptidase activity
D3Z87_01625	COG0457	Tetratricopeptide repeat
D3Z87_01630	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_01635	COG0366	Alpha amylase catalytic
D3Z87_01640	COG0803	Belongs to the bacterial solute-binding protein 9 family
D3Z87_01645	COG1121	(ABC) transporter
D3Z87_01650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3Z87_01655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z87_01660	COG2310	stress, protein
D3Z87_01665	COG2310	stress, protein
D3Z87_01670	COG2310	stress, protein
D3Z87_01675	COG0861	Integral membrane protein TerC family
D3Z87_01685	COG3853	Toxic anion resistance protein (TelA)
D3Z87_01690	COG0477	Major facilitator Superfamily
D3Z87_01700	COG2814	Major facilitator Superfamily
D3Z87_01705	COG0640	Transcriptional regulator
D3Z87_01710	COG0517	IMP dehydrogenase activity
D3Z87_01710	COG4175	Glycine betaine
D3Z87_01715	COG4176	ABC-type proline glycine betaine transport system permease component
D3Z87_01720	COG2113	Glycine betaine
D3Z87_01725	COG1473	amidohydrolase
D3Z87_01730	COG1288	antiporter activity
D3Z87_01740	COG0366	Alpha amylase catalytic
D3Z87_01745	COG0039	L-malate dehydrogenase activity
D3Z87_01750	COG1620	l-lactate permease
D3Z87_01755	COG2814	Major facilitator Superfamily
D3Z87_01760	COG1846	Transcriptional regulator
D3Z87_01765	COG1280	lysine exporter protein (LysE YggA)
D3Z87_01770	COG3403	YqcI/YcgG family
D3Z87_01775	COG1113	amino acid transport
D3Z87_01780	COG3665	Urea carboxylase-associated protein
D3Z87_01785	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D3Z87_01790	COG1660	Displays ATPase and GTPase activities
D3Z87_01800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D3Z87_01805	COG2226	methyltransferase
D3Z87_01810	COG0583	DNA-binding transcription factor activity
D3Z87_01815	COG3458	cephalosporin-C deacetylase activity
D3Z87_01820	COG3541	Predicted nucleotidyltransferase
D3Z87_01825	COG0506	proline dehydrogenase activity
D3Z87_01830	COG1012	belongs to the aldehyde dehydrogenase family
D3Z87_01835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3Z87_01840	COG2508	Transcriptional regulator
D3Z87_01845	COG3689	TIGRFAM TIGR03943 family protein
D3Z87_01850	COG0701	Predicted permease
D3Z87_01855	COG2267	carboxylic ester hydrolase activity
D3Z87_01860	COG0492	ferredoxin-NADP+ reductase activity
D3Z87_01865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3Z87_01865	COG1587	Uroporphyrinogen-III synthase
D3Z87_01870	COG2146	nitrite reductase [NAD(P)H] activity
D3Z87_01875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3Z87_01880	COG0243	molybdopterin cofactor binding
D3Z87_01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3Z87_01890	COG2223	nitrite transmembrane transporter activity
D3Z87_01895	COG1469	GTP cyclohydrolase I activity
D3Z87_01900	COG1376	ErfK ybiS ycfS ynhG family protein
D3Z87_01910	COG0523	cobalamin synthesis protein
D3Z87_01915	COG0765	amino acid transport
D3Z87_01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z87_01925	COG1714	RDD family
D3Z87_01935	COG2723	6-phospho-beta-galactosidase activity
D3Z87_01945	COG3209	COG3209 Rhs family protein
D3Z87_01950	COG3290	protein histidine kinase activity
D3Z87_01950	COG0840	transmembrane signaling receptor activity
D3Z87_01955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D3Z87_01960	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D3Z87_01965	COG1733	regulation of RNA biosynthetic process
D3Z87_01970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_01985	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D3Z87_01990	COG2814	Major facilitator Superfamily
D3Z87_02000	COG0697	spore germination
D3Z87_02005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z87_02015	COG2364	Membrane
D3Z87_02020	COG1126	abc transporter atp-binding protein
D3Z87_02025	COG0765	amino acid transport
D3Z87_02030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z87_02035	COG0583	DNA-binding transcription factor activity
D3Z87_02040	COG0163	prenyltransferase activity
D3Z87_02045	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D3Z87_02060	COG0596	Alpha beta hydrolase
D3Z87_02065	COG3104	oligopeptide transport
D3Z87_02070	COG5434	Belongs to the glycosyl hydrolase 28 family
D3Z87_02080	COG0697	spore germination
D3Z87_02090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D3Z87_02095	COG1136	(ABC) transporter
D3Z87_02100	COG0577	efflux transmembrane transporter activity
D3Z87_02105	COG0745	RESPONSE REGULATOR receiver
D3Z87_02110	COG5002	protein histidine kinase activity
D3Z87_02110	COG3850	Histidine kinase
D3Z87_02115	COG0457	Tetratricopeptide repeat
D3Z87_02135	COG0527	aspartate kinase activity
D3Z87_02140	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z87_02145	COG4605	iron ion homeostasis
D3Z87_02150	COG4604	ABC transporter, ATP-binding protein
D3Z87_02155	COG4607	ABC-type enterochelin transport system periplasmic component
D3Z87_02160	COG2814	Major facilitator Superfamily
D3Z87_02165	COG1309	transcriptional regulator
D3Z87_02170	COG0778	Nitroreductase
D3Z87_02175	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D3Z87_02180	COG0640	Transcriptional regulator
D3Z87_02185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z87_02190	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D3Z87_02195	COG1012	belongs to the aldehyde dehydrogenase family
D3Z87_02200	COG4975	Glucose uptake
D3Z87_02205	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_02210	COG4549	nuclear export factor GLE1
D3Z87_02215	COG1276	copper resistance
D3Z87_02215	COG2372	response to copper ion
D3Z87_02220	COG1349	DNA-binding transcription factor activity
D3Z87_02230	COG2213	PTS system mannitol-specific
D3Z87_02235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z87_02240	COG0246	Mannitol dehydrogenase
D3Z87_02245	COG0473	3-isopropylmalate dehydrogenase activity
D3Z87_02250	COG0681	Belongs to the peptidase S26 family
D3Z87_02255	COG0412	Dienelactone hydrolase
D3Z87_02260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D3Z87_02270	COG0561	phosphatase activity
D3Z87_02275	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D3Z87_02280	COG1914	H( )-stimulated, divalent metal cation uptake system
D3Z87_02285	COG4336	lyase activity
D3Z87_02290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D3Z87_02295	COG1984	allophanate hydrolase subunit 2
D3Z87_02300	COG1414	Transcriptional regulator
D3Z87_02305	COG2755	lipolytic protein G-D-S-L family
D3Z87_02315	COG2329	Antibiotic biosynthesis monooxygenase
D3Z87_02320	COG0768	penicillin binding
D3Z87_02325	COG4989	oxidoreductase activity
D3Z87_02330	COG3711	transcriptional antiterminator
D3Z87_02335	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z87_02340	COG2226	methyltransferase
D3Z87_02345	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_02350	COG1917	Cupin 2, conserved barrel domain protein
D3Z87_02355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z87_02360	COG3871	stress protein (general stress protein 26)
D3Z87_02370	COG2814	Major facilitator Superfamily
D3Z87_02375	COG1522	sequence-specific DNA binding
D3Z87_02380	COG0551	DNA topoisomerase type I activity
D3Z87_02380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3Z87_02385	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D3Z87_02390	COG3706	GGDEF domain
D3Z87_02395	COG5298	Protein conserved in bacteria
D3Z87_02400	COG1215	transferase activity, transferring glycosyl groups
D3Z87_02410	COG0531	amino acid
D3Z87_02415	COG0494	nUDIX hydrolase
D3Z87_02420	COG0028	Belongs to the TPP enzyme family
D3Z87_02435	COG1914	H( )-stimulated, divalent metal cation uptake system
D3Z87_02440	COG2261	transglycosylase associated protein
D3Z87_02445	COG4876	unkown
D3Z87_02450	COG2217	Heavy metal translocating P-type atpase
D3Z87_02455	COG3729	General stress protein
D3Z87_02460	COG0662	Cupin 2, conserved barrel domain protein
D3Z87_02465	COG2329	Antibiotic biosynthesis monooxygenase
D3Z87_02470	COG3546	catalase activity
D3Z87_02475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3Z87_02480	COG3290	protein histidine kinase activity
D3Z87_02485	COG4565	transcriptional regulatory protein
D3Z87_02490	COG1301	dicarboxylic acid transport
D3Z87_02495	COG0628	permease
D3Z87_02500	COG1131	(ABC) transporter
D3Z87_02505	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D3Z87_02515	COG1960	acyl-CoA dehydrogenase activity
D3Z87_02530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3Z87_02535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_02540	COG1181	Belongs to the D-alanine--D-alanine ligase family
D3Z87_02545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D3Z87_02555	COG0513	Belongs to the DEAD box helicase family
D3Z87_02560	COG3402	PFAM membrane-flanked domain
D3Z87_02565	COG3428	Bacterial PH domain
D3Z87_02575	COG0705	Rhomboid family
D3Z87_02580	COG0736	holo-[acyl-carrier-protein] synthase activity
D3Z87_02585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D3Z87_02590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3Z87_02595	COG0864	Transcriptional regulator
D3Z87_02600	COG2337	Toxic component of a toxin-antitoxin (TA) module
D3Z87_02605	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z87_02610	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z87_02615	COG2172	sigma factor antagonist activity
D3Z87_02620	COG2208	phosphoserine phosphatase activity
D3Z87_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z87_02630	COG2172	sigma factor antagonist activity
D3Z87_02635	COG1191	sigma factor activity
D3Z87_02640	COG2208	phosphoserine phosphatase activity
D3Z87_02655	COG1673	EVE domain
D3Z87_02665	COG2183	response to ionizing radiation
D3Z87_02675	COG3091	SprT-like family
D3Z87_02715	COG0582	viral genome integration into host DNA
D3Z87_02720	COG2856	Zn peptidase
D3Z87_02725	COG1396	sequence-specific DNA binding
D3Z87_02750	COG1674	ftsk spoiiie
D3Z87_02755	COG2946	Replication initiation factor
D3Z87_02790	COG0433	COG0433 Predicted ATPase
D3Z87_02800	COG5644	endopeptidase inhibitor activity
D3Z87_02805	COG0741	lytic transglycosylase activity
D3Z87_02805	COG0791	NLP P60 protein
D3Z87_02825	COG0457	Tetratricopeptide repeat
D3Z87_02840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z87_02845	COG1522	sequence-specific DNA binding
D3Z87_02850	COG1522	sequence-specific DNA binding
D3Z87_02855	COG1335	isochorismatase
D3Z87_02860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D3Z87_02865	COG2814	Major facilitator Superfamily
D3Z87_02885	COG0693	protein deglycase activity
D3Z87_02890	COG1278	Cold shock
D3Z87_02895	COG1329	Transcriptional regulator
D3Z87_02910	COG1917	Cupin 2, conserved barrel domain protein
D3Z87_02910	COG2207	Transcriptional regulator
D3Z87_02915	COG0697	spore germination
D3Z87_02920	COG2207	Transcriptional regulator
D3Z87_02920	COG3708	Transcriptional regulator
D3Z87_02925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z87_02930	COG0477	Major facilitator Superfamily
D3Z87_02940	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D3Z87_02955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z87_02960	COG2030	dehydratase
D3Z87_02965	COG3545	Serine hydrolase
D3Z87_02970	COG1733	regulation of RNA biosynthetic process
D3Z87_02975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z87_02980	COG1733	regulation of RNA biosynthetic process
D3Z87_02985	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3Z87_02990	COG2814	Major facilitator Superfamily
D3Z87_02995	COG1309	transcriptional regulator
D3Z87_03005	COG0640	Transcriptional regulator
D3Z87_03010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3Z87_03020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z87_03025	COG0697	spore germination
D3Z87_03030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z87_03035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3Z87_03040	COG0640	Transcriptional regulator
D3Z87_03045	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3Z87_03060	COG4585	Histidine kinase
D3Z87_03065	COG2197	response regulator
D3Z87_03070	COG2409	Drug exporters of the RND superfamily
D3Z87_03075	COG0596	Alpha beta hydrolase
D3Z87_03080	COG1811	Na channel or pump
D3Z87_03085	COG4978	Transcriptional regulator
D3Z87_03085	COG0789	Transcriptional regulator
D3Z87_03090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3Z87_03095	COG0778	Nitroreductase
D3Z87_03100	COG0346	lactoylglutathione lyase activity
D3Z87_03105	COG2259	Doxx family
D3Z87_03110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_03125	COG2323	membrane
D3Z87_03130	COG2323	membrane
D3Z87_03135	COG0071	Belongs to the small heat shock protein (HSP20) family
D3Z87_03150	COG1309	transcriptional regulator
D3Z87_03160	COG0456	acetyltransferase
D3Z87_03170	COG1113	amino acid transport
D3Z87_03175	COG2318	DinB family
D3Z87_03180	COG1846	Transcriptional regulator
D3Z87_03185	COG2409	Drug exporters of the RND superfamily
D3Z87_03185	COG1033	growth of symbiont in host cell
D3Z87_03190	COG0778	Nitroreductase
D3Z87_03195	COG1846	Transcriptional regulator
D3Z87_03200	COG2814	Major facilitator Superfamily
D3Z87_03205	COG0730	response to heat
D3Z87_03210	COG1802	Transcriptional regulator
D3Z87_03215	COG3858	chitin binding
D3Z87_03215	COG1388	LysM domain
D3Z87_03220	COG1819	glycosyl
D3Z87_03230	COG1785	Belongs to the alkaline phosphatase family
D3Z87_03235	COG5646	InterPro IPR014922
D3Z87_03245	COG0454	-acetyltransferase
D3Z87_03250	COG1078	dGTPase activity
D3Z87_03255	COG1388	LysM domain
D3Z87_03260	COG2814	Major facilitator Superfamily
D3Z87_03265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3Z87_03270	COG1447	Phosphotransferase system cellobiose-specific component IIA
D3Z87_03275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3Z87_03280	COG2723	6-phospho-beta-galactosidase activity
D3Z87_03285	COG2188	Transcriptional regulator
D3Z87_03290	COG1940	carbohydrate kinase activity
D3Z87_03295	COG1482	cell wall glycoprotein biosynthetic process
D3Z87_03300	COG4124	Belongs to the glycosyl hydrolase 26 family
D3Z87_03345	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D3Z87_03350	COG0802	atpase or kinase
D3Z87_03355	COG1214	PFAM Peptidase M22, glycoprotease
D3Z87_03360	COG0456	acetyltransferase
D3Z87_03365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D3Z87_03370	COG0488	(ABC) transporter
D3Z87_03375	COG0315	cyclic pyranopterin monophosphate synthase activity
D3Z87_03380	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D3Z87_03385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3Z87_03390	COG0805	protein transport
D3Z87_03400	COG1266	CAAX protease self-immunity
D3Z87_03405	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D3Z87_03410	COG0459	protein refolding
D3Z87_03425	COG3378	Phage plasmid primase P4 family
D3Z87_03440	COG0270	DNA (cytosine-5-)-methyltransferase activity
D3Z87_03445	COG0270	DNA (cytosine-5-)-methyltransferase activity
D3Z87_03465	COG1401	restriction endodeoxyribonuclease activity
D3Z87_03490	COG1073	alpha beta
D3Z87_03495	COG0457	Tetratricopeptide repeat
D3Z87_03500	COG1063	alcohol dehydrogenase
D3Z87_03505	COG2211	Major facilitator Superfamily
D3Z87_03510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3Z87_03515	COG1842	Phage shock protein A
D3Z87_03520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D3Z87_03525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D3Z87_03530	COG4260	virion core protein, lumpy skin disease virus
D3Z87_03540	COG2814	Major facilitator Superfamily
D3Z87_03545	COG1063	alcohol dehydrogenase
D3Z87_03550	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D3Z87_03555	COG0823	Involved in the tonB-independent uptake of proteins
D3Z87_03570	COG2267	carboxylic ester hydrolase activity
D3Z87_03580	COG2132	Multicopper oxidase
D3Z87_03585	COG1113	amino acid transport
D3Z87_03595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3Z87_03600	COG0714	Associated with various cellular activities
D3Z87_03605	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D3Z87_03610	COG1305	Transglutaminase-like
D3Z87_03615	COG0519	Catalyzes the synthesis of GMP from XMP
D3Z87_03615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D3Z87_03620	COG2252	PERMEase
D3Z87_03625	COG3064	Membrane
D3Z87_03635	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D3Z87_03645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D3Z87_03650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D3Z87_03655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D3Z87_03660	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D3Z87_03665	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3Z87_03670	COG0047	phosphoribosylformylglycinamidine synthase activity
D3Z87_03675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3Z87_03680	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D3Z87_03685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D3Z87_03690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D3Z87_03695	COG0138	bifunctional purine biosynthesis protein purh
D3Z87_03700	COG0151	Belongs to the GarS family
D3Z87_03705	COG1522	sequence-specific DNA binding
D3Z87_03710	COG0531	amino acid
D3Z87_03720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D3Z87_03725	COG1470	cell adhesion involved in biofilm formation
D3Z87_03730	COG4496	protein, YerC YecD
D3Z87_03735	COG0069	glutamate synthase activity
D3Z87_03740	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D3Z87_03745	COG0210	DNA helicase
D3Z87_03750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D3Z87_03755	COG4851	CamS sex pheromone cAM373 precursor
D3Z87_03760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3Z87_03765	COG1285	pathogenesis
D3Z87_03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3Z87_03775	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D3Z87_03780	COG0154	amidase activity
D3Z87_03785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D3Z87_03790	COG1309	transcriptional regulator
D3Z87_03795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3Z87_03800	COG1597	lipid kinase activity
D3Z87_03805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3Z87_03810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3Z87_03815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3Z87_03820	COG1002	Type II restriction enzyme, methylase subunits
D3Z87_03825	COG1061	Type III restriction enzyme res subunit
D3Z87_03830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3Z87_03850	COG5444	nuclease activity
D3Z87_03855	COG3391	amine dehydrogenase activity
D3Z87_03860	COG0457	Tetratricopeptide repeat
D3Z87_03870	COG0217	transcriptional regulatory protein
D3Z87_03880	COG1309	transcriptional regulator
D3Z87_03885	COG3631	Ketosteroid isomerase-related protein
D3Z87_03890	COG0702	epimerase
D3Z87_03905	COG3546	catalase activity
D3Z87_03910	COG0454	-acetyltransferase
D3Z87_03920	COG5578	integral membrane protein
D3Z87_03925	COG2972	Histidine kinase
D3Z87_03930	COG4753	response regulator
D3Z87_03930	COG2207	Transcriptional regulator
D3Z87_03935	COG1653	transport
D3Z87_03940	COG1175	transmembrane transport
D3Z87_03945	COG0395	ABC-type sugar transport system, permease component
D3Z87_03950	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D3Z87_03955	COG2207	Transcriptional regulator
D3Z87_03960	COG2755	lipolytic protein G-D-S-L family
D3Z87_03970	COG5578	integral membrane protein
D3Z87_03975	COG3401	FG-GAP repeat protein
D3Z87_03980	COG3401	FG-GAP repeat protein
D3Z87_03990	COG1874	Beta-galactosidase
D3Z87_04000	COG1653	transport
D3Z87_04005	COG4209	transmembrane transport
D3Z87_04010	COG0395	ABC-type sugar transport system, permease component
D3Z87_04015	COG1486	melibiose metabolic process
D3Z87_04020	COG2323	membrane
D3Z87_04025	COG2329	Antibiotic biosynthesis monooxygenase
D3Z87_04030	COG0346	lactoylglutathione lyase activity
D3Z87_04045	COG5583	Uncharacterized small protein (DUF2292)
D3Z87_04050	COG0670	Belongs to the BI1 family
D3Z87_04055	COG0697	spore germination
D3Z87_04060	COG1846	Transcriptional regulator
D3Z87_04065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3Z87_04075	COG2124	cytochrome p450
D3Z87_04075	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3Z87_04080	COG1368	sulfuric ester hydrolase activity
D3Z87_04085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D3Z87_04090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3Z87_04095	COG1442	glycosyl transferase family 8
D3Z87_04100	COG1216	Glycosyl transferase, family 2
D3Z87_04105	COG1442	glycosyl transferase family 8
D3Z87_04110	COG2223	nitrite transmembrane transporter activity
D3Z87_04115	COG1011	Hydrolase
D3Z87_04120	COG0531	amino acid
D3Z87_04125	COG1012	belongs to the aldehyde dehydrogenase family
D3Z87_04130	COG0840	transmembrane signaling receptor activity
D3Z87_04135	COG0488	(ABC) transporter
D3Z87_04145	COG0789	Transcriptional regulator
D3Z87_04150	COG2814	Major facilitator Superfamily
D3Z87_04165	COG0488	(ABC) transporter
D3Z87_04170	COG0513	Belongs to the DEAD box helicase family
D3Z87_04175	COG0456	acetyltransferase
D3Z87_04180	COG2130	NADP-dependent
D3Z87_04190	COG2211	Major facilitator Superfamily
D3Z87_04195	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D3Z87_04200	COG1120	ATPase activity
D3Z87_04205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z87_04210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z87_04215	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D3Z87_04235	COG3866	Pectate lyase
D3Z87_04240	COG0471	metal ion transport
D3Z87_04245	COG3290	protein histidine kinase activity
D3Z87_04250	COG4565	transcriptional regulatory protein
D3Z87_04255	COG3181	Tripartite tricarboxylate transporter family receptor
D3Z87_04260	COG2851	Citrate transporter
D3Z87_04265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z87_04270	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D3Z87_04275	COG1254	Belongs to the acylphosphatase family
D3Z87_04280	COG2258	MOSC domain
D3Z87_04300	COG0024	Methionine aminopeptidase
D3Z87_04305	COG1263	PTS System
D3Z87_04305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_04310	COG1368	sulfuric ester hydrolase activity
D3Z87_04325	COG1115	amino acid carrier protein
D3Z87_04330	COG0531	amino acid
D3Z87_04345	COG0697	spore germination
D3Z87_04350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_04350	COG1263	PTS System
D3Z87_04355	COG0366	Alpha amylase catalytic
D3Z87_04360	COG2188	Transcriptional regulator
D3Z87_04365	COG0778	Nitroreductase
D3Z87_04370	COG0737	Belongs to the 5'-nucleotidase family
D3Z87_04375	COG0693	protein deglycase activity
D3Z87_04380	COG2814	Major facilitator Superfamily
D3Z87_04385	COG4840	Belongs to the UPF0435 family
D3Z87_04390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3Z87_04395	COG4980	gas vesicle protein
D3Z87_04400	COG1295	ribonuclease BN
D3Z87_04405	COG0477	Major facilitator Superfamily
D3Z87_04410	COG0387	Pfam Sodium calcium exchanger
D3Z87_04420	COG0668	transmembrane transport
D3Z87_04425	COG0535	radical SAM domain protein
D3Z87_04435	COG0726	polysaccharide deacetylase
D3Z87_04440	COG2084	Dehydrogenase
D3Z87_04445	COG0598	Magnesium transport protein CorA
D3Z87_04450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D3Z87_04455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3Z87_04465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3Z87_04470	COG4637	Psort location Cytoplasmic, score
D3Z87_04480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3Z87_04485	COG0022	dehydrogenase e1 component
D3Z87_04490	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3Z87_04495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3Z87_04500	COG3284	Transcriptional regulator
D3Z87_04510	COG1742	UPF0060 membrane protein
D3Z87_04535	COG4842	Belongs to the WXG100 family
D3Z87_04540	COG1486	melibiose metabolic process
D3Z87_04545	COG1737	Transcriptional regulator
D3Z87_04550	COG1263	PTS System
D3Z87_04550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_04555	COG1132	(ABC) transporter
D3Z87_04560	COG1132	(ABC) transporter
D3Z87_04565	COG2259	Doxx family
D3Z87_04570	COG2514	catechol 2,3-dioxygenase activity
D3Z87_04575	COG1917	Cupin 2, conserved barrel domain protein
D3Z87_04575	COG4977	sequence-specific DNA binding
D3Z87_04580	COG2814	Major facilitator Superfamily
D3Z87_04585	COG1082	Xylose isomerase domain protein TIM barrel
D3Z87_04590	COG0673	inositol 2-dehydrogenase activity
D3Z87_04595	COG4585	Histidine kinase
D3Z87_04600	COG2197	response regulator
D3Z87_04605	COG1131	(ABC) transporter
D3Z87_04610	COG0842	Transport permease protein
D3Z87_04610	COG1511	domain protein
D3Z87_04615	COG0842	Transport permease protein
D3Z87_04620	COG1695	Transcriptional regulator
D3Z87_04625	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D3Z87_04630	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D3Z87_04635	COG1309	transcriptional regulator
D3Z87_04640	COG2814	Major facilitator Superfamily
D3Z87_04645	COG2318	DinB family
D3Z87_04650	COG2814	Major facilitator Superfamily
D3Z87_04655	COG1846	Transcriptional regulator
D3Z87_04660	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D3Z87_04660	COG0392	lysyltransferase activity
D3Z87_04665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z87_04670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z87_04675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z87_04680	COG0384	phenazine biosynthesis protein PhzF
D3Z87_04685	COG0778	Nitroreductase
D3Z87_04700	COG1090	epimerase
D3Z87_04705	COG2137	regulation of response to DNA damage stimulus
D3Z87_04715	COG2814	Major facilitator Superfamily
D3Z87_04730	COG3103	Sh3 type 3 domain protein
D3Z87_04735	COG5658	integral membrane protein
D3Z87_04740	COG0596	Alpha beta hydrolase
D3Z87_04745	COG0463	Glycosyl transferase, family 2
D3Z87_04750	COG4485	Bacterial membrane protein, YfhO
D3Z87_04755	COG1988	membrane-bound metal-dependent
D3Z87_04760	COG1194	a g-specific adenine glycosylase
D3Z87_04770	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_04785	COG3557	Belongs to the UPF0374 family
D3Z87_04790	COG1132	(ABC) transporter
D3Z87_04795	COG4129	membrane
D3Z87_04800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D3Z87_04805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3Z87_04810	COG0735	belongs to the Fur family
D3Z87_04920	COG4326	sporulation control protein
D3Z87_04930	COG5577	PFAM Coat F domain
D3Z87_04935	COG3340	Belongs to the peptidase S51 family
D3Z87_04940	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D3Z87_04945	COG0277	FAD linked oxidase domain protein
D3Z87_04955	COG0753	catalase activity
D3Z87_04960	COG1116	anion transmembrane transporter activity
D3Z87_04965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3Z87_04970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3Z87_04975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z87_04985	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D3Z87_04995	COG1476	TRANSCRIPTIONal
D3Z87_05005	COG3382	B3 4 domain protein
D3Z87_05010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D3Z87_05020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D3Z87_05025	COG0789	Transcriptional regulator
D3Z87_05030	COG1664	Polymer-forming cytoskeletal
D3Z87_05035	COG1664	Polymer-forming cytoskeletal
D3Z87_05040	COG2766	serine protein kinase
D3Z87_05045	COG2718	Belongs to the UPF0229 family
D3Z87_05050	COG1846	Transcriptional regulator
D3Z87_05055	COG1566	PFAM secretion protein HlyD family protein
D3Z87_05060	COG2814	Major facilitator Superfamily
D3Z87_05065	COG0655	NAD(P)H dehydrogenase (quinone) activity
D3Z87_05085	COG1725	Transcriptional regulator
D3Z87_05090	COG1131	(ABC) transporter
D3Z87_05095	COG1131	(ABC) transporter
D3Z87_05100	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D3Z87_05105	COG1278	Cold shock
D3Z87_05115	COG1464	Belongs to the NlpA lipoprotein family
D3Z87_05120	COG3706	GGDEF domain
D3Z87_05125	COG1823	symporter activity
D3Z87_05145	COG5577	PFAM Coat F domain
D3Z87_05150	COG4085	toxin activity
D3Z87_05150	COG1525	nuclease
D3Z87_05150	COG0737	Belongs to the 5'-nucleotidase family
D3Z87_05155	COG3764	Sortase (surface protein transpeptidase)
D3Z87_05160	COG0564	pseudouridine synthase activity
D3Z87_05170	COG0517	IMP dehydrogenase activity
D3Z87_05175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3Z87_05180	COG3153	acetyltransferase
D3Z87_05180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3Z87_05185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3Z87_05190	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D3Z87_05195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D3Z87_05200	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D3Z87_05205	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D3Z87_05210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3Z87_05215	COG2203	Gaf domain
D3Z87_05215	COG4585	Histidine kinase
D3Z87_05220	COG2197	response regulator
D3Z87_05225	COG0431	NADPH-dependent FMN reductase
D3Z87_05240	COG1388	LysM domain
D3Z87_05240	COG0791	NLP P60 protein
D3Z87_05245	COG1959	2 iron, 2 sulfur cluster binding
D3Z87_05250	COG0668	transmembrane transport
D3Z87_05255	COG2719	SpoVR family
D3Z87_05260	COG1785	Belongs to the alkaline phosphatase family
D3Z87_05265	COG1388	LysM domain
D3Z87_05265	COG0791	NLP P60 protein
D3Z87_05270	COG0583	DNA-binding transcription factor activity
D3Z87_05275	COG0372	Belongs to the citrate synthase family
D3Z87_05280	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_05285	COG0531	amino acid
D3Z87_05290	COG0733	neurotransmitter:sodium symporter activity
D3Z87_05295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z87_05300	COG0456	acetyltransferase
D3Z87_05315	COG1595	DNA-templated transcription, initiation
D3Z87_05320	COG0667	Aldo Keto reductase
D3Z87_05325	COG0204	Acyl-transferase
D3Z87_05330	COG1253	flavin adenine dinucleotide binding
D3Z87_05335	COG0789	Transcriptional regulator
D3Z87_05340	COG0436	Aminotransferase
D3Z87_05345	COG1253	flavin adenine dinucleotide binding
D3Z87_05350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3Z87_05355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3Z87_05360	COG0584	glycerophosphoryl diester phosphodiesterase
D3Z87_05370	COG0668	transmembrane transport
D3Z87_05375	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D3Z87_05380	COG0726	polysaccharide deacetylase
D3Z87_05385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3Z87_05390	COG1757	Na H antiporter
D3Z87_05395	COG0589	response to stress
D3Z87_05405	COG1132	(ABC) transporter
D3Z87_05410	COG1132	(ABC) transporter
D3Z87_05415	COG0702	epimerase
D3Z87_05435	COG0189	ligase activity
D3Z87_05440	COG0189	ligase activity
D3Z87_05445	COG4399	Belongs to the UPF0754 family
D3Z87_05450	COG3679	Belongs to the UPF0342 family
D3Z87_05455	COG4335	DNA alkylation repair
D3Z87_05460	COG0561	phosphatase activity
D3Z87_05465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3Z87_05470	COG0475	glutathione-regulated potassium exporter activity
D3Z87_05475	COG0490	domain, Protein
D3Z87_05485	COG1024	Enoyl-CoA hydratase
D3Z87_05495	COG4152	abc transporter atp-binding protein
D3Z87_05500	COG1668	transmembrane transport
D3Z87_05505	COG0420	3'-5' exonuclease activity
D3Z87_05510	COG4717	serine-type aminopeptidase activity
D3Z87_05515	COG3481	metal-dependent phosphohydrolase, HD sub domain
D3Z87_05525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3Z87_05555	COG1846	Transcriptional regulator
D3Z87_05560	COG4980	gas vesicle protein
D3Z87_05575	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D3Z87_05580	COG0537	adenosine 5'-monophosphoramidase activity
D3Z87_05585	COG1131	(ABC) transporter
D3Z87_05590	COG4473	ABC transporter
D3Z87_05600	COG1473	amidohydrolase
D3Z87_05605	COG3069	C4-dicarboxylate transmembrane transporter activity
D3Z87_05615	COG2329	Antibiotic biosynthesis monooxygenase
D3Z87_05620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3Z87_05625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D3Z87_05640	COG1309	transcriptional regulator
D3Z87_05645	COG1511	domain protein
D3Z87_05650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3Z87_05655	COG4377	Putative membrane peptidase family (DUF2324)
D3Z87_05665	COG1363	Peptidase, m42
D3Z87_05670	COG4405	Protein conserved in bacteria
D3Z87_05675	COG1301	dicarboxylic acid transport
D3Z87_05685	COG1234	tRNA 3'-trailer cleavage
D3Z87_05690	COG0095	Lipoate-protein ligase
D3Z87_05695	COG0702	epimerase
D3Z87_05700	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z87_05710	COG0501	Belongs to the peptidase M48B family
D3Z87_05725	COG0604	alcohol dehydrogenase
D3Z87_05730	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D3Z87_05735	COG0406	alpha-ribazole phosphatase activity
D3Z87_05740	COG0183	Belongs to the thiolase family
D3Z87_05745	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z87_05750	COG1268	BioY protein
D3Z87_05760	COG0723	plastoquinol--plastocyanin reductase activity
D3Z87_05760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3Z87_05765	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_05775	COG4903	ComK protein
D3Z87_05780	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_05790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3Z87_05805	COG0398	Pfam SNARE associated Golgi protein
D3Z87_05810	COG0681	Belongs to the peptidase S26 family
D3Z87_05815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3Z87_05820	COG1846	Transcriptional regulator
D3Z87_05825	COG0738	Major facilitator superfamily
D3Z87_05830	COG0673	inositol 2-dehydrogenase activity
D3Z87_05835	COG0561	phosphatase activity
D3Z87_05840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3Z87_05845	COG1609	Transcriptional regulator
D3Z87_05850	COG3180	Ammonia monooxygenase
D3Z87_05855	COG2814	Major facilitator Superfamily
D3Z87_05855	COG0477	Major facilitator Superfamily
D3Z87_05860	COG4533	DNA binding
D3Z87_05870	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D3Z87_05875	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D3Z87_05880	COG1074	ATP-dependent DNA helicase activity
D3Z87_05885	COG0420	3'-5' exonuclease activity
D3Z87_05895	COG1403	HNH endonuclease
D3Z87_05935	COG5337	Spore coat protein CotH
D3Z87_05940	COG0179	Fumarylacetoacetate (FAA) hydrolase
D3Z87_05980	COG0367	asparagine synthase
D3Z87_05985	COG2318	DinB family
D3Z87_05990	COG1562	ergosterol biosynthetic process
D3Z87_05995	COG0534	Mate efflux family protein
D3Z87_06000	COG1917	Cupin 2, conserved barrel domain protein
D3Z87_06000	COG2207	Transcriptional regulator
D3Z87_06005	COG1609	Transcriptional regulator
D3Z87_06010	COG0673	inositol 2-dehydrogenase activity
D3Z87_06015	COG2318	DinB family
D3Z87_06020	COG1279	arginine transmembrane transporter activity
D3Z87_06025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3Z87_06030	COG1357	PFAM Pentapeptide repeats (8 copies)
D3Z87_06035	COG2267	carboxylic ester hydrolase activity
D3Z87_06040	COG0529	Catalyzes the synthesis of activated sulfate
D3Z87_06045	COG2046	Belongs to the sulfate adenylyltransferase family
D3Z87_06050	COG0175	sulfate reduction
D3Z87_06055	COG2045	Belongs to the ComB family
D3Z87_06060	COG1809	phosphosulfolactate synthase activity
D3Z87_06065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z87_06070	COG4948	Mandelate Racemase Muconate Lactonizing
D3Z87_06075	COG2814	Major facilitator Superfamily
D3Z87_06080	COG0454	-acetyltransferase
D3Z87_06085	COG2153	protein acetylation
D3Z87_06090	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D3Z87_06090	COG0646	methionine synthase
D3Z87_06095	COG1666	GTP binding
D3Z87_06100	COG2996	Protein conserved in bacteria
D3Z87_06120	COG1695	Transcriptional regulator
D3Z87_06145	COG1307	EDD domain protein, DegV family
D3Z87_06150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z87_06165	COG0561	phosphatase activity
D3Z87_06170	COG1073	alpha beta
D3Z87_06175	COG2151	metal-sulfur cluster biosynthetic enzyme
D3Z87_06185	COG0277	FAD linked oxidase domain protein
D3Z87_06190	COG2271	Major facilitator Superfamily
D3Z87_06195	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D3Z87_06210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3Z87_06215	COG0505	Belongs to the CarA family
D3Z87_06220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3Z87_06225	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D3Z87_06240	COG2267	carboxylic ester hydrolase activity
D3Z87_06250	COG1744	ABC transporter substrate-binding protein PnrA-like
D3Z87_06265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3Z87_06270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3Z87_06275	COG5504	Zn-dependent protease
D3Z87_06280	COG0444	Belongs to the ABC transporter superfamily
D3Z87_06285	COG4608	Belongs to the ABC transporter superfamily
D3Z87_06295	COG0601	transmembrane transport
D3Z87_06300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3Z87_06310	COG0180	Tryptophanyl-tRNA synthetase
D3Z87_06315	COG4166	transmembrane transport
D3Z87_06320	COG0601	transmembrane transport
D3Z87_06325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3Z87_06330	COG0444	Belongs to the ABC transporter superfamily
D3Z87_06335	COG4608	Belongs to the ABC transporter superfamily
D3Z87_06340	COG2814	Major facilitator Superfamily
D3Z87_06345	COG0456	acetyltransferase
D3Z87_06350	COG1393	Belongs to the ArsC family
D3Z87_06355	COG0861	Integral membrane protein TerC family
D3Z87_06360	COG4862	establishment of competence for transformation
D3Z87_06365	COG4469	Competence protein
D3Z87_06370	COG1164	Oligoendopeptidase f
D3Z87_06390	COG2346	COG2346, Truncated hemoglobins
D3Z87_06395	COG0741	lytic transglycosylase activity
D3Z87_06400	COG4116	CYTH
D3Z87_06410	COG2357	RelA SpoT domain protein
D3Z87_06415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D3Z87_06420	COG0564	pseudouridine synthase activity
D3Z87_06425	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D3Z87_06430	COG0569	domain protein
D3Z87_06430	COG0475	glutathione-regulated potassium exporter activity
D3Z87_06435	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D3Z87_06440	COG0352	thiamine-phosphate diphosphorylase activity
D3Z87_06445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3Z87_06450	COG2104	thiamine diphosphate biosynthetic process
D3Z87_06455	COG2022	thiamine diphosphate biosynthetic process
D3Z87_06460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3Z87_06465	COG0351	phosphomethylpyrimidine kinase
D3Z87_06470	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D3Z87_06525	COG0210	DNA helicase
D3Z87_06535	COG2153	protein acetylation
D3Z87_06540	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D3Z87_06545	COG2382	esterase
D3Z87_06550	COG0626	cystathionine gamma-synthase activity
D3Z87_06555	COG0626	cystathionine gamma-synthase activity
D3Z87_06560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z87_06565	COG5505	Protein of unknown function (DUF819)
D3Z87_06595	COG3677	Transposase
D3Z87_06610	COG5484	DNA packaging
D3Z87_06615	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D3Z87_06620	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_06630	COG3711	transcriptional antiterminator
D3Z87_06630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z87_06635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3Z87_06635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z87_06635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3Z87_06640	COG1482	cell wall glycoprotein biosynthetic process
D3Z87_06650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z87_06660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D3Z87_06680	COG0109	protoheme IX farnesyltransferase activity
D3Z87_06690	COG0726	polysaccharide deacetylase
D3Z87_06705	COG5504	Zn-dependent protease
D3Z87_06710	COG2205	protein histidine kinase activity
D3Z87_06725	COG2427	Protein of unknown function (DUF1641)
D3Z87_06735	COG1051	belongs to the nudix hydrolase family
D3Z87_06745	COG2124	cytochrome p450
D3Z87_06750	COG1819	glycosyl
D3Z87_06760	COG1587	Uroporphyrinogen-III synthase
D3Z87_06765	COG0390	transport system, permease component
D3Z87_06770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3Z87_06775	COG0697	spore germination
D3Z87_06780	COG4297	protein containing double-stranded beta helix domain
D3Z87_06790	COG1252	NADH dehydrogenase
D3Z87_06795	COG1904	glucuronate isomerase
D3Z87_06800	COG2211	Major facilitator Superfamily
D3Z87_06805	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D3Z87_06810	COG1063	alcohol dehydrogenase
D3Z87_06815	COG1312	Catalyzes the dehydration of D-mannonate
D3Z87_06820	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_06825	COG2271	Major facilitator Superfamily
D3Z87_06830	COG1609	Transcriptional regulator
D3Z87_06835	COG0246	Mannitol dehydrogenase
D3Z87_06840	COG2721	sulfolactate sulfo-lyase activity
D3Z87_06845	COG0730	response to heat
D3Z87_06850	COG2318	DinB family
D3Z87_06855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3Z87_06860	COG0457	Tetratricopeptide repeat
D3Z87_06870	COG2350	Protein conserved in bacteria
D3Z87_06875	COG1388	LysM domain
D3Z87_06875	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3Z87_06875	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_06885	COG4195	phage-related replication protein
D3Z87_06890	COG3546	catalase activity
D3Z87_06895	COG2856	Zn peptidase
D3Z87_06900	COG1396	sequence-specific DNA binding
D3Z87_06910	COG1522	sequence-specific DNA binding
D3Z87_06915	COG1484	DNA-dependent DNA replication
D3Z87_06935	COG1595	DNA-templated transcription, initiation
D3Z87_06940	COG5484	DNA packaging
D3Z87_06940	COG3728	DNA packaging
D3Z87_06945	COG1783	phage Terminase large subunit
D3Z87_06950	COG5518	Phage portal protein
D3Z87_06955	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D3Z87_06960	COG4653	Phage capsid family
D3Z87_07010	COG5412	phage tail tape measure protein
D3Z87_07010	COG3953	SLT domain
D3Z87_07015	COG1652	LysM domain
D3Z87_07020	COG4193	domain, Protein
D3Z87_07030	COG3628	GPW Gp25 family protein
D3Z87_07035	COG3299	homolog of phage Mu protein gp47
D3Z87_07040	COG3778	Protein conserved in bacteria
D3Z87_07080	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_07080	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3Z87_07095	COG0306	phosphate transporter
D3Z87_07100	COG1392	Phosphate transport regulator
D3Z87_07105	COG0531	amino acid
D3Z87_07110	COG0346	lactoylglutathione lyase activity
D3Z87_07115	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D3Z87_07120	COG0463	Glycosyl transferase, family 2
D3Z87_07125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3Z87_07130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3Z87_07135	COG2362	D-Aminopeptidase
D3Z87_07140	COG0601	transmembrane transport
D3Z87_07145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3Z87_07150	COG0444	Belongs to the ABC transporter superfamily
D3Z87_07155	COG4166	transmembrane transport
D3Z87_07160	COG1619	proteins homologs of microcin C7 resistance protein MccF
D3Z87_07165	COG4948	Mandelate Racemase Muconate Lactonizing
D3Z87_07170	COG0791	NLP P60 protein
D3Z87_07175	COG4608	Belongs to the ABC transporter superfamily
D3Z87_07180	COG2706	6-phosphogluconolactonase activity
D3Z87_07185	COG1834	amidinotransferase
D3Z87_07190	COG1607	acyl-coa hydrolase
D3Z87_07195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3Z87_07195	COG1017	nitric oxide dioxygenase activity
D3Z87_07205	COG2323	membrane
D3Z87_07210	COG2318	DinB family
D3Z87_07215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z87_07220	COG2076	Multidrug Resistance protein
D3Z87_07225	COG2076	Multidrug Resistance protein
D3Z87_07230	COG0788	formyltetrahydrofolate deformylase activity
D3Z87_07235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D3Z87_07240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D3Z87_07245	COG1764	response to oxidative stress
D3Z87_07250	COG1846	Transcriptional regulator
D3Z87_07255	COG1764	response to oxidative stress
D3Z87_07265	COG0590	tRNA wobble adenosine to inosine editing
D3Z87_07270	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D3Z87_07345	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z87_07350	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D3Z87_07355	COG1122	ATPase activity
D3Z87_07360	COG4721	ABC-type cobalt transport system, permease component
D3Z87_07370	COG0745	RESPONSE REGULATOR receiver
D3Z87_07375	COG5002	protein histidine kinase activity
D3Z87_07375	COG3850	Histidine kinase
D3Z87_07380	COG3212	peptidase
D3Z87_07385	COG3212	peptidase
D3Z87_07400	COG2239	Acts as a magnesium transporter
D3Z87_07405	COG0789	Transcriptional regulator
D3Z87_07420	COG1846	Transcriptional regulator
D3Z87_07425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3Z87_07430	COG0726	polysaccharide deacetylase
D3Z87_07435	COG1408	metallophosphoesterase
D3Z87_07445	COG0463	Glycosyl transferase, family 2
D3Z87_07450	COG3285	dna ligase
D3Z87_07450	COG1793	dna ligase
D3Z87_07455	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D3Z87_07460	COG5001	Diguanylate cyclase
D3Z87_07460	COG3300	MHYT domain
D3Z87_07465	COG0586	Pfam SNARE associated Golgi protein
D3Z87_07470	COG0861	Integral membrane protein TerC family
D3Z87_07475	COG1191	sigma factor activity
D3Z87_07495	COG0501	Belongs to the peptidase M48B family
D3Z87_07500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3Z87_07515	COG3594	Acyltransferase
D3Z87_07520	COG5002	protein histidine kinase activity
D3Z87_07525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3Z87_07530	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D3Z87_07535	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D3Z87_07540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3Z87_07545	COG0436	Aminotransferase
D3Z87_07555	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D3Z87_07560	COG0235	Class ii aldolase
D3Z87_07565	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D3Z87_07570	COG3339	Conserved Protein
D3Z87_07585	COG3852	Histidine kinase
D3Z87_07590	COG1846	Transcriptional regulator
D3Z87_07595	COG1360	Flagellar Motor Protein
D3Z87_07600	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D3Z87_07605	COG0542	response to heat
D3Z87_07610	COG3949	Membrane
D3Z87_07615	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D3Z87_07620	COG0720	synthase
D3Z87_07625	COG0602	queuosine metabolic process
D3Z87_07630	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D3Z87_07635	COG1733	regulation of RNA biosynthetic process
D3Z87_07640	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_07645	COG4641	Protein conserved in bacteria
D3Z87_07645	COG1388	LysM domain
D3Z87_07650	COG1388	LysM domain
D3Z87_07655	COG3858	chitin binding
D3Z87_07660	COG3858	chitin binding
D3Z87_07670	COG4873	Protein conserved in bacteria
D3Z87_07680	COG3773	Cell wall hydrolase
D3Z87_07685	COG2244	polysaccharide biosynthetic process
D3Z87_07690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_07695	COG2217	Heavy metal translocating P-type atpase
D3Z87_07705	COG0006	proline dipeptidase activity
D3Z87_07710	COG1609	Transcriptional regulator
D3Z87_07715	COG3711	transcriptional antiterminator
D3Z87_07720	COG1263	PTS System
D3Z87_07720	COG2190	(PTS) system
D3Z87_07720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_07725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z87_07730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3Z87_07740	COG1533	DNA photolyase activity
D3Z87_07745	COG0456	acetyltransferase
D3Z87_07750	COG0840	transmembrane signaling receptor activity
D3Z87_07755	COG2084	Dehydrogenase
D3Z87_07760	COG2340	Cysteine-rich secretory protein family
D3Z87_07765	COG0768	penicillin binding
D3Z87_07770	COG4191	Histidine kinase
D3Z87_07775	COG0436	Aminotransferase
D3Z87_07785	COG0835	chemotaxis
D3Z87_07785	COG0784	Response regulator, receiver
D3Z87_07795	COG2814	Major facilitator Superfamily
D3Z87_07800	COG1376	ErfK ybiS ycfS ynhG family protein
D3Z87_07805	COG1408	metallophosphoesterase
D3Z87_07810	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_07815	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_07820	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_07830	COG2200	EAL domain
D3Z87_07835	COG4703	Protein of unknown function (DUF1797)
D3Z87_07840	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D3Z87_07850	COG0517	IMP dehydrogenase activity
D3Z87_07855	COG0583	DNA-binding transcription factor activity
D3Z87_07860	COG0716	FMN binding
D3Z87_07870	COG0716	FMN binding
D3Z87_07875	COG2171	N-acyltransferase activity
D3Z87_07880	COG1473	amidohydrolase
D3Z87_07890	COG0668	transmembrane transport
D3Z87_07895	COG0450	alkyl hydroperoxide reductase
D3Z87_07900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_07915	COG0746	molybdenum cofactor guanylyltransferase activity
D3Z87_07920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3Z87_07925	COG0303	'Molybdopterin
D3Z87_07930	COG1763	Mo-molybdopterin cofactor biosynthetic process
D3Z87_07935	COG0314	molybdopterin synthase activity
D3Z87_07940	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D3Z87_07945	COG1132	(ABC) transporter
D3Z87_07950	COG1132	(ABC) transporter
D3Z87_07960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3Z87_07965	COG1136	(ABC) transporter
D3Z87_07970	COG0577	efflux transmembrane transporter activity
D3Z87_07975	COG1349	DNA-binding transcription factor activity
D3Z87_07980	COG1105	Belongs to the carbohydrate kinase PfkB family
D3Z87_07985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3Z87_07985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3Z87_07985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z87_07990	COG0681	Belongs to the peptidase S26 family
D3Z87_08000	COG0488	(ABC) transporter
D3Z87_08005	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3Z87_08010	COG2309	aminopeptidase activity
D3Z87_08020	COG1077	Cell shape determining protein MreB Mrl
D3Z87_08025	COG2002	toxin-antitoxin pair type II binding
D3Z87_08030	COG3852	Histidine kinase
D3Z87_08035	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D3Z87_08035	COG2105	PFAM AIG2 family protein
D3Z87_08040	COG0569	domain protein
D3Z87_08045	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D3Z87_08050	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D3Z87_08060	COG0561	phosphatase activity
D3Z87_08065	COG0242	peptide deformylase activity
D3Z87_08075	COG0497	DNA recombination
D3Z87_08080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3Z87_08085	COG0022	dehydrogenase e1 component
D3Z87_08090	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3Z87_08095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3Z87_08100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_08110	COG1982	Orn Lys Arg decarboxylase major
D3Z87_08115	COG4476	Belongs to the UPF0223 family
D3Z87_08120	COG4493	Belongs to the UPF0637 family
D3Z87_08130	COG0483	inositol monophosphate 1-phosphatase activity
D3Z87_08140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D3Z87_08160	COG1595	DNA-templated transcription, initiation
D3Z87_08190	COG4896	Protein conserved in bacteria
D3Z87_08200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D3Z87_08205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D3Z87_08210	COG2066	Belongs to the glutaminase family
D3Z87_08215	COG4838	Belongs to the UPF0358 family
D3Z87_08220	COG0772	Belongs to the SEDS family
D3Z87_08225	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D3Z87_08230	COG1612	heme a metabolic process
D3Z87_08235	COG0109	protoheme IX farnesyltransferase activity
D3Z87_08240	COG2010	Cytochrome c
D3Z87_08240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3Z87_08245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3Z87_08250	COG1845	cytochrome c oxidase, subunit III
D3Z87_08255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D3Z87_08260	COG3336	cytochrome c oxidase
D3Z87_08270	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D3Z87_08275	COG2340	Cysteine-rich secretory protein family
D3Z87_08290	COG3679	Belongs to the UPF0342 family
D3Z87_08295	COG4471	UPF0298 protein
D3Z87_08300	COG0742	ribosomal rna small subunit methyltransferase
D3Z87_08305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D3Z87_08310	COG3314	Sporulation integral membrane protein YlbJ
D3Z87_08315	COG1752	Esterase of the alpha-beta hydrolase superfamily
D3Z87_08320	COG3480	Lon protease (S16) C-terminal proteolytic domain
D3Z87_08325	COG1323	Belongs to the UPF0348 family
D3Z87_08335	COG1399	metal-binding, possibly nucleic acid-binding protein
D3Z87_08340	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D3Z87_08350	COG0454	-acetyltransferase
D3Z87_08355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3Z87_08360	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D3Z87_08365	COG2001	Belongs to the MraZ family
D3Z87_08370	COG0275	rRNA processing
D3Z87_08375	COG4839	cell division protein FtsL
D3Z87_08385	COG0768	penicillin binding
D3Z87_08390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D3Z87_08395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3Z87_08400	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D3Z87_08405	COG0772	Belongs to the SEDS family
D3Z87_08410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3Z87_08415	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D3Z87_08420	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D3Z87_08425	COG3879	Bacterial protein of unknown function (DUF881)
D3Z87_08430	COG3879	Bacterial protein of unknown function (DUF881)
D3Z87_08435	COG3856	small basic protein
D3Z87_08440	COG0849	cell division
D3Z87_08445	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D3Z87_08460	COG1191	sigma factor activity
D3Z87_08465	COG1191	sigma factor activity
D3Z87_08470	COG1119	ATPase activity
D3Z87_08475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3Z87_08480	COG1873	PFAM PRC-barrel domain
D3Z87_08490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D3Z87_08495	COG1799	cell septum assembly
D3Z87_08500	COG0762	integral membrane protein
D3Z87_08505	COG2302	S4 RNA-binding domain
D3Z87_08510	COG3599	regulation of cell shape
D3Z87_08515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D3Z87_08520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3Z87_08525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D3Z87_08530	COG0564	pseudouridine synthase activity
D3Z87_08535	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D3Z87_08540	COG2233	PERMEase
D3Z87_08545	COG0540	Belongs to the ATCase OTCase family
D3Z87_08550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3Z87_08555	COG0505	Belongs to the CarA family
D3Z87_08560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3Z87_08565	COG0543	2 iron, 2 sulfur cluster binding
D3Z87_08570	COG0167	dihydroorotate dehydrogenase activity
D3Z87_08575	COG0284	orotidine-5'-phosphate decarboxylase activity
D3Z87_08580	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D3Z87_08585	COG0175	sulfate reduction
D3Z87_08590	COG0306	phosphate transporter
D3Z87_08595	COG2046	Belongs to the sulfate adenylyltransferase family
D3Z87_08600	COG0529	Catalyzes the synthesis of activated sulfate
D3Z87_08605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3Z87_08610	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D3Z87_08615	COG1648	precorrin-2 dehydrogenase activity
D3Z87_08625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D3Z87_08630	COG1561	YicC-like family, N-terminal region
D3Z87_08635	COG2052	Domain of unknown function (DUF370)
D3Z87_08640	COG0194	GDP metabolic process
D3Z87_08645	COG1758	RNA polymerase activity
D3Z87_08650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3Z87_08655	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D3Z87_08660	COG0242	peptide deformylase activity
D3Z87_08665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D3Z87_08670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3Z87_08670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D3Z87_08675	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D3Z87_08680	COG0631	protein serine/threonine phosphatase activity
D3Z87_08685	COG0515	serine threonine protein kinase
D3Z87_08685	COG2815	serine threonine protein kinase
D3Z87_08690	COG1162	GTPase activity
D3Z87_08695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D3Z87_08700	COG1564	THIamine pyrophosphokinase
D3Z87_08710	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D3Z87_08715	COG1302	Protein conserved in bacteria
D3Z87_08720	COG1461	Dihydroxyacetone kinase
D3Z87_08725	COG1760	l-serine dehydratase
D3Z87_08730	COG1760	l-serine dehydratase
D3Z87_08735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D3Z87_08740	COG2050	protein possibly involved in aromatic compounds catabolism
D3Z87_08740	COG1349	DNA-binding transcription factor activity
D3Z87_08745	COG0416	fatty acid biosynthetic process
D3Z87_08750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3Z87_08755	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_08760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z87_08765	COG0571	ribonuclease III activity
D3Z87_08770	COG1196	nuclear chromosome segregation
D3Z87_08775	COG0552	protein localization to endoplasmic reticulum
D3Z87_08785	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D3Z87_08790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D3Z87_08795	COG0228	four-way junction DNA binding
D3Z87_08800	COG1837	Belongs to the UPF0109 family
D3Z87_08810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D3Z87_08815	COG0336	Belongs to the RNA methyltransferase TrmD family
D3Z87_08820	COG0335	large ribosomal subunit rRNA binding
D3Z87_08825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D3Z87_08830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D3Z87_08840	COG2257	FlhB HrpN YscU SpaS Family
D3Z87_08845	COG0045	succinate-CoA ligase (ADP-forming) activity
D3Z87_08850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D3Z87_08855	COG0758	DNA mediated transformation
D3Z87_08860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3Z87_08865	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D3Z87_08870	COG4974	Belongs to the 'phage' integrase family
D3Z87_08875	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D3Z87_08880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D3Z87_08885	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D3Z87_08890	COG1815	bacterial-type flagellum-dependent cell motility
D3Z87_08895	COG1558	bacterial-type flagellum-dependent cell motility
D3Z87_08900	COG1677	Flagellar hook-basal body complex protein FliE
D3Z87_08905	COG1766	The M ring may be actively involved in energy transduction
D3Z87_08910	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3Z87_08915	COG1317	bacterial-type flagellum organization
D3Z87_08920	COG1157	protein secretion by the type III secretion system
D3Z87_08925	COG2882	bacterial-type flagellum organization
D3Z87_08930	COG3334	PFAM MgtE intracellular
D3Z87_08935	COG3144	bacterial-type flagellum assembly
D3Z87_08940	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D3Z87_08945	COG4786	Flagellar basal body rod
D3Z87_08950	COG1582	Flagellar protein (FlbD)
D3Z87_08955	COG1580	Controls the rotational direction of flagella during chemotaxis
D3Z87_08960	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3Z87_08965	COG1776	CheC inhibitor of MCP methylation
D3Z87_08965	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3Z87_08970	COG2201	protein-glutamate methylesterase activity
D3Z87_08975	COG3190	flagellar
D3Z87_08980	COG1338	Plays a role in the flagellum-specific transport system
D3Z87_08985	COG1987	bacterial-type flagellum assembly
D3Z87_08990	COG1684	flagellar biosynthetic protein fliR
D3Z87_08995	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3Z87_09000	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3Z87_09005	COG1419	protein localization to endoplasmic reticulum
D3Z87_09010	COG0455	bacterial-type flagellum organization
D3Z87_09015	COG2201	protein-glutamate methylesterase activity
D3Z87_09020	COG0643	Histidine kinase
D3Z87_09020	COG2198	Histidine kinase
D3Z87_09025	COG0835	chemotaxis
D3Z87_09030	COG1776	CheC inhibitor of MCP methylation
D3Z87_09035	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D3Z87_09040	COG1191	sigma factor activity
D3Z87_09050	COG0052	Belongs to the universal ribosomal protein uS2 family
D3Z87_09055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D3Z87_09060	COG0528	UMP kinase activity
D3Z87_09065	COG0233	cytoplasmic translational termination
D3Z87_09070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D3Z87_09075	COG4589	Belongs to the CDS family
D3Z87_09080	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D3Z87_09085	COG0750	zinc metalloprotease
D3Z87_09090	COG0442	prolyl-tRNA aminoacylation
D3Z87_09095	COG2176	DNA-directed DNA polymerase activity
D3Z87_09100	COG0779	Required for maturation of 30S ribosomal subunits
D3Z87_09105	COG0195	Participates in both transcription termination and antitermination
D3Z87_09110	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D3Z87_09115	COG1358	cellular component organization or biogenesis
D3Z87_09120	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D3Z87_09125	COG1550	Protein conserved in bacteria
D3Z87_09130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D3Z87_09135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D3Z87_09140	COG0196	riboflavin kinase activity
D3Z87_09145	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D3Z87_09150	COG1185	polyribonucleotide nucleotidyltransferase activity
D3Z87_09155	COG0726	polysaccharide deacetylase
D3Z87_09160	COG0612	Peptidase, M16
D3Z87_09165	COG1873	PFAM PRC-barrel domain
D3Z87_09170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3Z87_09175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3Z87_09180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3Z87_09185	COG0527	aspartate kinase activity
D3Z87_09190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3Z87_09195	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D3Z87_09200	COG0740	serine-type endopeptidase activity
D3Z87_09210	COG1674	ftsk spoiiie
D3Z87_09210	COG4980	gas vesicle protein
D3Z87_09215	COG2188	Transcriptional regulator
D3Z87_09220	COG2814	Major facilitator Superfamily
D3Z87_09225	COG0612	Peptidase, M16
D3Z87_09230	COG0612	Peptidase, M16
D3Z87_09235	COG0300	oxidoreductase activity
D3Z87_09250	COG1426	Protein conserved in bacteria
D3Z87_09255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D3Z87_09260	COG1058	Belongs to the CinA family
D3Z87_09260	COG1546	Belongs to the CinA family
D3Z87_09265	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D3Z87_09270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3Z87_09275	COG1418	mRNA catabolic process
D3Z87_09280	COG1692	metallophosphoesterase
D3Z87_09285	COG2359	stage V sporulation protein S
D3Z87_09290	COG1063	alcohol dehydrogenase
D3Z87_09295	COG0156	8-amino-7-oxononanoate synthase activity
D3Z87_09300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3Z87_09305	COG4550	Control of competence regulator ComK, YlbF/YmcA
D3Z87_09315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D3Z87_09320	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D3Z87_09335	COG3226	Transcriptional regulator
D3Z87_09340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z87_09350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3Z87_09355	COG3321	synthase
D3Z87_09360	COG2070	2-Nitropropane dioxygenase
D3Z87_09360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3Z87_09365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z87_09370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3Z87_09375	COG3425	synthase
D3Z87_09380	COG1024	Enoyl-CoA hydratase
D3Z87_09385	COG1024	Enoyl-CoA hydratase
D3Z87_09390	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z87_09390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_09390	COG0300	oxidoreductase activity
D3Z87_09390	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_09390	COG3321	synthase
D3Z87_09395	COG0300	oxidoreductase activity
D3Z87_09395	COG3321	synthase
D3Z87_09395	COG4221	oxidoreductase activity
D3Z87_09395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z87_09400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z87_09400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3Z87_09400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_09400	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_09400	COG3321	synthase
D3Z87_09410	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D3Z87_09410	COG3321	synthase
D3Z87_09410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3Z87_09410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z87_09415	COG2124	cytochrome p450
D3Z87_09425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z87_09430	COG1404	Belongs to the peptidase S8 family
D3Z87_09435	COG4195	phage-related replication protein
D3Z87_09440	COG1764	response to oxidative stress
D3Z87_09445	COG2076	Multidrug Resistance protein
D3Z87_09450	COG2076	Multidrug Resistance protein
D3Z87_09465	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D3Z87_09470	COG1923	regulation of RNA biosynthetic process
D3Z87_09485	COG1780	Probably involved in ribonucleotide reductase function
D3Z87_09490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3Z87_09495	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3Z87_09500	COG4112	unkown
D3Z87_09505	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z87_09515	COG0464	growth
D3Z87_09520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D3Z87_09525	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D3Z87_09530	COG0789	Transcriptional regulator
D3Z87_09535	COG0174	glutamine synthetase
D3Z87_09555	COG4282	regulation of fungal-type cell wall biogenesis
D3Z87_09565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z87_09595	COG0135	phosphoribosylanthranilate isomerase activity
D3Z87_09600	COG2211	Major facilitator Superfamily
D3Z87_09605	COG3507	Belongs to the glycosyl hydrolase 43 family
D3Z87_09610	COG1940	carbohydrate kinase activity
D3Z87_09615	COG2115	Belongs to the xylose isomerase family
D3Z87_09620	COG1070	Carbohydrate kinase
D3Z87_09630	COG1525	nuclease
D3Z87_09635	COG2814	Major facilitator Superfamily
D3Z87_09640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3Z87_09650	COG0756	dUTP diphosphatase activity
D3Z87_09660	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D3Z87_09685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3Z87_09695	COG3832	glyoxalase III activity
D3Z87_09710	COG0697	spore germination
D3Z87_09715	COG0531	amino acid
D3Z87_09745	COG4195	phage-related replication protein
D3Z87_09755	COG0346	lactoylglutathione lyase activity
D3Z87_09765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D3Z87_09770	COG1388	LysM domain
D3Z87_09775	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3Z87_09780	COG4224	UPF0291 protein
D3Z87_09785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D3Z87_09795	COG3763	UPF0154 protein
D3Z87_09805	COG0785	Cytochrome C biogenesis protein
D3Z87_09815	COG4846	Membrane protein involved in cytochrome C biogenesis
D3Z87_09825	COG0071	Belongs to the small heat shock protein (HSP20) family
D3Z87_09840	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D3Z87_09845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_09865	COG0824	Thioesterase
D3Z87_09875	COG4841	protein insertion into membrane
D3Z87_09880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D3Z87_09885	COG1832	CoA-binding protein
D3Z87_09890	COG0187	DNA topoisomerase II activity
D3Z87_09895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3Z87_09905	COG1115	amino acid carrier protein
D3Z87_09910	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D3Z87_09920	COG5520	Belongs to the glycosyl hydrolase 30 family
D3Z87_09925	COG3507	Belongs to the glycosyl hydrolase 43 family
D3Z87_09930	COG2246	polysaccharide biosynthetic process
D3Z87_09935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3Z87_09940	COG0586	Pfam SNARE associated Golgi protein
D3Z87_09945	COG2404	hydrolase activity, acting on ester bonds
D3Z87_09950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D3Z87_09955	COG1024	Enoyl-CoA hydratase
D3Z87_09960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D3Z87_09965	COG0511	ligase activity, forming carbon-carbon bonds
D3Z87_09970	COG0439	Biotin carboxylase
D3Z87_09975	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z87_09980	COG1960	acyl-CoA dehydrogenase activity
D3Z87_09990	COG1649	PFAM Uncharacterised BCR, COG1649
D3Z87_10000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_10000	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D3Z87_10010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_10015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_10020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_10025	COG2027	D-alanyl-D-alanine carboxypeptidase
D3Z87_10030	COG2017	converts alpha-aldose to the beta-anomer
D3Z87_10035	COG0534	Mate efflux family protein
D3Z87_10050	COG0582	viral genome integration into host DNA
D3Z87_10055	COG0166	Belongs to the GPI family
D3Z87_10060	COG0405	Gamma-glutamyltransferase
D3Z87_10065	COG0583	DNA-binding transcription factor activity
D3Z87_10070	COG0604	alcohol dehydrogenase
D3Z87_10075	COG0493	'glutamate synthase
D3Z87_10080	COG0067	glutamate synthase
D3Z87_10080	COG0069	glutamate synthase activity
D3Z87_10080	COG0070	glutamate synthase
D3Z87_10085	COG0583	DNA-binding transcription factor activity
D3Z87_10090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D3Z87_10095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3Z87_10105	COG0300	oxidoreductase activity
D3Z87_10110	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D3Z87_10120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z87_10125	COG2814	Major facilitator Superfamily
D3Z87_10130	COG1070	Carbohydrate kinase
D3Z87_10135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3Z87_10165	COG5278	phosphoserine phosphatase activity
D3Z87_10165	COG0840	transmembrane signaling receptor activity
D3Z87_10170	COG2368	4-hydroxyphenylacetate
D3Z87_10175	COG4305	rare lipoprotein A
D3Z87_10180	COG3619	membrane
D3Z87_10185	COG3866	Pectate lyase
D3Z87_10190	COG2135	peptidase activity
D3Z87_10210	COG0456	acetyltransferase
D3Z87_10230	COG2720	vancomycin resistance protein
D3Z87_10240	COG3655	Transcriptional regulator
D3Z87_10245	COG3739	integral membrane protein
D3Z87_10250	COG0583	DNA-binding transcription factor activity
D3Z87_10255	COG0697	spore germination
D3Z87_10265	COG0693	protein deglycase activity
D3Z87_10270	COG2367	Beta-lactamase
D3Z87_10295	COG3848	Pyruvate phosphate dikinase
D3Z87_10295	COG0574	Belongs to the PEP-utilizing enzyme family
D3Z87_10300	COG0726	polysaccharide deacetylase
D3Z87_10310	COG2314	TM2 domain
D3Z87_10315	COG1396	sequence-specific DNA binding
D3Z87_10330	COG2135	peptidase activity
D3Z87_10365	COG0457	Tetratricopeptide repeat
D3Z87_10390	COG5290	Psort location Cytoplasmic, score
D3Z87_10415	COG5444	nuclease activity
D3Z87_10420	COG4282	regulation of fungal-type cell wall biogenesis
D3Z87_10425	COG1231	oxidoreductase activity
D3Z87_10430	COG5434	Belongs to the glycosyl hydrolase 28 family
D3Z87_10435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3Z87_10440	COG0662	Cupin 2, conserved barrel domain protein
D3Z87_10440	COG2207	Transcriptional regulator
D3Z87_10445	COG0456	acetyltransferase
D3Z87_10450	COG1309	transcriptional regulator
D3Z87_10455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z87_10460	COG3708	Transcriptional regulator
D3Z87_10465	COG2378	regulation of single-species biofilm formation
D3Z87_10475	COG0640	Transcriptional regulator
D3Z87_10480	COG0741	lytic transglycosylase activity
D3Z87_10485	COG2322	membrane
D3Z87_10500	COG1619	proteins homologs of microcin C7 resistance protein MccF
D3Z87_10505	COG3239	Fatty acid desaturase
D3Z87_10510	COG4585	Histidine kinase
D3Z87_10515	COG2197	response regulator
D3Z87_10520	COG3584	3D domain protein
D3Z87_10520	COG1388	LysM domain
D3Z87_10525	COG0514	ATP-dependent DNA helicase (RecQ)
D3Z87_10540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D3Z87_10545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3Z87_10560	COG0071	Belongs to the small heat shock protein (HSP20) family
D3Z87_10585	COG1012	belongs to the aldehyde dehydrogenase family
D3Z87_10590	COG1657	PFAM Prenyltransferase squalene oxidase
D3Z87_10595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D3Z87_10600	COG0733	neurotransmitter:sodium symporter activity
D3Z87_10605	COG0385	Bile acid
D3Z87_10610	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3Z87_10615	COG0567	Dehydrogenase, E1 component
D3Z87_10620	COG4548	von Willebrand factor, type A
D3Z87_10625	COG0714	Associated with various cellular activities
D3Z87_10630	COG2032	superoxide dismutase activity
D3Z87_10635	COG1388	LysM domain
D3Z87_10635	COG0791	NLP P60 protein
D3Z87_10640	COG1819	glycosyl
D3Z87_10645	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D3Z87_10650	COG0534	Mate efflux family protein
D3Z87_10655	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z87_10660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3Z87_10665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3Z87_10675	COG2962	Rard protein
D3Z87_10690	COG2610	gluconate transmembrane transporter activity
D3Z87_10695	COG1942	4-Oxalocrotonate Tautomerase
D3Z87_10700	COG1733	regulation of RNA biosynthetic process
D3Z87_10705	COG0778	Nitroreductase
D3Z87_10710	COG0400	carboxylic ester hydrolase activity
D3Z87_10715	COG0346	lactoylglutathione lyase activity
D3Z87_10725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3Z87_10730	COG0793	Belongs to the peptidase S41A family
D3Z87_10730	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_10735	COG2226	methyltransferase
D3Z87_10745	COG1876	peptidase activity
D3Z87_10750	COG0813	purine-nucleoside phosphorylase activity
D3Z87_10765	COG0671	phosphoesterase, PA-phosphatase related
D3Z87_10790	COG4479	Belongs to the UPF0346 family
D3Z87_10800	COG1509	lysine 2,3-aminomutase activity
D3Z87_10805	COG0456	acetyltransferase
D3Z87_10810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3Z87_10815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D3Z87_10820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D3Z87_10825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3Z87_10835	COG0456	acetyltransferase
D3Z87_10840	COG0463	Glycosyl transferase, family 2
D3Z87_10855	COG4641	Protein conserved in bacteria
D3Z87_10860	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D3Z87_10865	COG1086	Polysaccharide biosynthesis protein
D3Z87_10875	COG3331	DNA recombination
D3Z87_10930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3Z87_10965	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D3Z87_10970	COG0756	dUTP diphosphatase activity
D3Z87_10975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_10995	COG1372	Participates in initiation and elongation during chromosome replication
D3Z87_10995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3Z87_11000	COG1372	Participates in initiation and elongation during chromosome replication
D3Z87_11000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3Z87_11005	COG1780	Probably involved in ribonucleotide reductase function
D3Z87_11095	COG0270	DNA (cytosine-5-)-methyltransferase activity
D3Z87_11105	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
D3Z87_11110	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3Z87_11135	COG3584	3D domain protein
D3Z87_11140	COG0587	DNA-directed DNA polymerase activity
D3Z87_11145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3Z87_11150	COG0358	DNA primase activity
D3Z87_11155	COG0305	Participates in initiation and elongation during chromosome replication
D3Z87_11165	COG2887	Belongs to the helicase family. UvrD subfamily
D3Z87_11195	COG5434	Belongs to the glycosyl hydrolase 28 family
D3Z87_11195	COG3420	alginic acid biosynthetic process
D3Z87_11200	COG4195	phage-related replication protein
D3Z87_11215	COG2135	peptidase activity
D3Z87_11220	COG1793	dna ligase
D3Z87_11275	COG4474	Belongs to the UPF0398 family
D3Z87_11285	COG1388	LysM domain
D3Z87_11305	COG3645	SOS response
D3Z87_11305	COG3646	Phage regulatory protein
D3Z87_11360	COG3655	Transcriptional regulator
D3Z87_11375	COG0582	viral genome integration into host DNA
D3Z87_11455	COG3655	Transcriptional regulator
D3Z87_11495	COG1395	domain, Protein
D3Z87_11510	COG0776	regulation of translation
D3Z87_11540	COG4373	Mu-like prophage FluMu protein gp28
D3Z87_11640	COG0582	viral genome integration into host DNA
D3Z87_11670	COG0739	heme binding
D3Z87_11670	COG1196	nuclear chromosome segregation
D3Z87_11670	COG0741	lytic transglycosylase activity
D3Z87_11680	COG2433	Pfam Transposase IS66
D3Z87_11690	COG4632	Exopolysaccharide biosynthesis protein
D3Z87_11690	COG5434	Belongs to the glycosyl hydrolase 28 family
D3Z87_11705	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3Z87_11720	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D3Z87_11725	COG0463	Glycosyl transferase, family 2
D3Z87_11730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_11735	COG3271	cysteine-type peptidase activity
D3Z87_11735	COG2274	protein secretion by the type I secretion system
D3Z87_11750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3Z87_11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3Z87_11790	COG5444	nuclease activity
D3Z87_11795	COG4282	regulation of fungal-type cell wall biogenesis
D3Z87_11810	COG1525	nuclease
D3Z87_11820	COG2746	aminoglycoside 3-N-acetyltransferase activity
D3Z87_11835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3Z87_11840	COG1086	Polysaccharide biosynthesis protein
D3Z87_11845	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D3Z87_11850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D3Z87_11855	COG1846	Transcriptional regulator
D3Z87_11860	COG0534	Mate efflux family protein
D3Z87_11870	COG4698	Protein conserved in bacteria
D3Z87_11875	COG2755	lipolytic protein G-D-S-L family
D3Z87_11880	COG1999	signal sequence binding
D3Z87_11890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D3Z87_11895	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D3Z87_11900	COG1272	protein, Hemolysin III
D3Z87_11905	COG0204	Acyl-transferase
D3Z87_11910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3Z87_11915	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D3Z87_11920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D3Z87_11930	COG2521	methyltransferase
D3Z87_11930	COG2136	Putative SAM-dependent methyltransferase
D3Z87_11940	COG0129	dihydroxy-acid dehydratase activity
D3Z87_11945	COG1413	lyase activity
D3Z87_11950	COG1418	mRNA catabolic process
D3Z87_11955	COG0386	Belongs to the glutathione peroxidase family
D3Z87_11960	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D3Z87_11965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3Z87_11970	COG1278	Cold shock
D3Z87_11990	COG0328	RNA-DNA hybrid ribonuclease activity
D3Z87_11995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D3Z87_12000	COG0328	RNA-DNA hybrid ribonuclease activity
D3Z87_12010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3Z87_12025	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D3Z87_12035	COG1755	Isoprenylcysteine carboxyl methyltransferase
D3Z87_12040	COG3424	synthase
D3Z87_12045	COG2233	PERMEase
D3Z87_12050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3Z87_12055	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D3Z87_12065	COG0800	Aldolase
D3Z87_12070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3Z87_12075	COG1609	Transcriptional regulator
D3Z87_12080	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D3Z87_12085	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_12090	COG1199	ATP-dependent helicase activity
D3Z87_12105	COG0116	Belongs to the methyltransferase superfamily
D3Z87_12120	COG4474	Belongs to the UPF0398 family
D3Z87_12130	COG3359	exonuclease
D3Z87_12135	COG1205	dead DEAH box helicase
D3Z87_12135	COG1111	helicase
D3Z87_12140	COG2190	(PTS) system
D3Z87_12145	COG0071	Belongs to the small heat shock protein (HSP20) family
D3Z87_12180	COG3331	DNA recombination
D3Z87_12185	COG4499	WXG100 protein secretion system (Wss), protein YukC
D3Z87_12185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3Z87_12195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D3Z87_12200	COG3935	DnaD domain protein
D3Z87_12205	COG0017	Asparaginyl-tRNA synthetase
D3Z87_12210	COG0436	Aminotransferase
D3Z87_12215	COG5353	protein conserved in bacteria
D3Z87_12225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3Z87_12225	COG1199	ATP-dependent helicase activity
D3Z87_12230	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D3Z87_12235	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D3Z87_12240	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D3Z87_12245	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D3Z87_12245	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D3Z87_12250	COG0617	tRNA 3'-terminal CCA addition
D3Z87_12255	COG0438	transferase activity, transferring glycosyl groups
D3Z87_12260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3Z87_12265	COG1803	Methylglyoxal synthase
D3Z87_12270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D3Z87_12275	COG1694	Mazg nucleotide pyrophosphohydrolase
D3Z87_12280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z87_12290	COG4347	Protein of unknown function (DUF1405)
D3Z87_12295	COG2010	Cytochrome c
D3Z87_12295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D3Z87_12300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D3Z87_12305	COG0723	plastoquinol--plastocyanin reductase activity
D3Z87_12315	COG5582	Belongs to the UPF0302 family
D3Z87_12320	COG0457	Tetratricopeptide repeat
D3Z87_12325	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D3Z87_12330	COG0287	Prephenate dehydrogenase
D3Z87_12335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3Z87_12340	COG0159	tryptophan synthase activity
D3Z87_12345	COG0133	tryptophan synthase activity
D3Z87_12350	COG0135	phosphoribosylanthranilate isomerase activity
D3Z87_12360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D3Z87_12365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3Z87_12370	COG4401	Chorismate mutase type I
D3Z87_12375	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D3Z87_12380	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D3Z87_12385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D3Z87_12390	COG0105	UTP biosynthetic process
D3Z87_12395	COG0142	geranyltranstransferase activity
D3Z87_12400	COG2226	methyltransferase
D3Z87_12405	COG0142	geranyltranstransferase activity
D3Z87_12415	COG0302	gtp cyclohydrolase
D3Z87_12420	COG0776	regulation of translation
D3Z87_12425	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D3Z87_12440	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D3Z87_12445	COG1160	GTP binding
D3Z87_12470	COG1304	FMN binding
D3Z87_12475	COG0539	negative regulation of cytoplasmic translation
D3Z87_12480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D3Z87_12490	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D3Z87_12495	COG2959	enzyme of heme biosynthesis
D3Z87_12500	COG3773	Cell wall hydrolase
D3Z87_12500	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_12505	COG2339	peptidase activity
D3Z87_12510	COG0492	ferredoxin-NADP+ reductase activity
D3Z87_12515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3Z87_12520	COG4862	establishment of competence for transformation
D3Z87_12525	COG1408	metallophosphoesterase
D3Z87_12535	COG1388	LysM domain
D3Z87_12540	COG1266	CAAX protease self-immunity
D3Z87_12545	COG0514	ATP-dependent DNA helicase (RecQ)
D3Z87_12550	COG4955	Helix-turn-helix domain
D3Z87_12555	COG1141	Ferredoxin
D3Z87_12560	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D3Z87_12565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3Z87_12570	COG0710	3-dehydroquinate dehydratase activity
D3Z87_12580	COG1595	DNA-templated transcription, initiation
D3Z87_12585	COG5002	protein histidine kinase activity
D3Z87_12590	COG0745	RESPONSE REGULATOR receiver
D3Z87_12595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3Z87_12600	COG1333	cytochrome c biogenesis protein
D3Z87_12605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_12610	COG1187	pseudouridine synthase activity
D3Z87_12615	COG0700	Nucleoside recognition
D3Z87_12620	COG2715	membrane protein required for spore maturation
D3Z87_12625	COG1686	Belongs to the peptidase S11 family
D3Z87_12635	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D3Z87_12640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D3Z87_12645	COG1547	Domain of unknown function (DUF309)
D3Z87_12650	COG0456	acetyltransferase
D3Z87_12655	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D3Z87_12660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3Z87_12660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3Z87_12665	COG0307	riboflavin synthase, alpha
D3Z87_12670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3Z87_12670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3Z87_12680	COG0681	Belongs to the peptidase S26 family
D3Z87_12690	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D3Z87_12715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D3Z87_12725	COG4086	secreted protein
D3Z87_12730	COG0019	diaminopimelate decarboxylase activity
D3Z87_12735	COG0697	spore germination
D3Z87_12750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3Z87_12770	COG1191	sigma factor activity
D3Z87_12775	COG2172	sigma factor antagonist activity
D3Z87_12780	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z87_12785	COG1686	Belongs to the peptidase S11 family
D3Z87_12790	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D3Z87_12795	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D3Z87_12800	COG4974	Belongs to the 'phage' integrase family
D3Z87_12810	COG0735	belongs to the Fur family
D3Z87_12815	COG1300	Membrane
D3Z87_12825	COG0281	malic enzyme
D3Z87_12830	COG1757	Na H antiporter
D3Z87_12835	COG1027	Aspartate ammonia-lyase
D3Z87_12840	COG0252	asparaginase activity
D3Z87_12845	COG1396	sequence-specific DNA binding
D3Z87_12850	COG1379	DNA repair
D3Z87_12855	COG0494	nUDIX hydrolase
D3Z87_12865	COG0667	Aldo Keto reductase
D3Z87_12875	COG1073	alpha beta
D3Z87_12885	COG4918	Iron-sulphur cluster biosynthesis
D3Z87_12890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D3Z87_12890	COG0456	acetyltransferase
D3Z87_12895	COG2329	Antibiotic biosynthesis monooxygenase
D3Z87_12900	COG0456	acetyltransferase
D3Z87_12910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3Z87_12930	COG0346	lactoylglutathione lyase activity
D3Z87_12935	COG1072	(Pantothenic acid kinase))
D3Z87_12940	COG3048	D-serine ammonia-lyase activity
D3Z87_12945	COG0300	oxidoreductase activity
D3Z87_12950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z87_12955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3Z87_12960	COG4187	Peptidase family M20/M25/M40
D3Z87_12965	COG1902	pentaerythritol trinitrate reductase activity
D3Z87_12970	COG0596	Alpha beta hydrolase
D3Z87_12980	COG1234	tRNA 3'-trailer cleavage
D3Z87_12985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D3Z87_12990	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D3Z87_12995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3Z87_13005	COG0706	membrane insertase activity
D3Z87_13010	COG3361	conserved protein (COG2071)
D3Z87_13015	COG2195	Cleaves the N-terminal amino acid of tripeptides
D3Z87_13020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D3Z87_13025	COG0346	lactoylglutathione lyase activity
D3Z87_13030	COG1376	ErfK ybiS ycfS ynhG family protein
D3Z87_13035	COG4129	membrane
D3Z87_13040	COG1126	abc transporter atp-binding protein
D3Z87_13045	COG0765	amino acid transport
D3Z87_13050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z87_13060	COG1597	lipid kinase activity
D3Z87_13065	COG2814	Major facilitator Superfamily
D3Z87_13070	COG4978	Transcriptional regulator
D3Z87_13070	COG0789	Transcriptional regulator
D3Z87_13075	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3Z87_13080	COG0022	dehydrogenase e1 component
D3Z87_13085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3Z87_13090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3Z87_13095	COG3426	butyrate kinase activity
D3Z87_13100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3Z87_13105	COG0280	phosphate acetyltransferase
D3Z87_13110	COG3290	protein histidine kinase activity
D3Z87_13110	COG3829	transcription factor binding
D3Z87_13120	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D3Z87_13125	COG2079	MmgE PrpD family protein
D3Z87_13130	COG0372	Belongs to the citrate synthase family
D3Z87_13135	COG1960	acyl-CoA dehydrogenase activity
D3Z87_13140	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3Z87_13145	COG0183	Belongs to the thiolase family
D3Z87_13150	COG0584	glycerophosphoryl diester phosphodiesterase
D3Z87_13155	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z87_13165	COG1902	pentaerythritol trinitrate reductase activity
D3Z87_13170	COG0745	RESPONSE REGULATOR receiver
D3Z87_13175	COG0750	zinc metalloprotease
D3Z87_13180	COG0497	DNA recombination
D3Z87_13185	COG1438	arginine binding
D3Z87_13190	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D3Z87_13195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D3Z87_13200	COG0142	geranyltranstransferase activity
D3Z87_13205	COG1722	exodeoxyribonuclease VII activity
D3Z87_13210	COG1570	exodeoxyribonuclease VII activity
D3Z87_13215	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D3Z87_13220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3Z87_13225	COG1302	Protein conserved in bacteria
D3Z87_13230	COG0439	Biotin carboxylase
D3Z87_13235	COG0511	ligase activity, forming carbon-carbon bonds
D3Z87_13275	COG3854	ATPases associated with a variety of cellular activities
D3Z87_13285	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D3Z87_13290	COG0006	proline dipeptidase activity
D3Z87_13295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D3Z87_13305	COG3872	metal-dependent enzyme
D3Z87_13315	COG1752	Esterase of the alpha-beta hydrolase superfamily
D3Z87_13320	COG1321	iron dependent repressor
D3Z87_13325	COG0095	Lipoate-protein ligase
D3Z87_13330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3Z87_13335	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D3Z87_13340	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D3Z87_13345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D3Z87_13350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D3Z87_13365	COG1396	sequence-specific DNA binding
D3Z87_13375	COG0681	Belongs to the peptidase S26 family
D3Z87_13400	COG4940	Competence protein ComGF
D3Z87_13410	COG4970	Tfp pilus assembly protein FimT
D3Z87_13415	COG4537	Required for transformation and DNA binding
D3Z87_13420	COG1459	type II secretion system
D3Z87_13425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D3Z87_13435	COG0598	Magnesium transport protein CorA
D3Z87_13440	COG1253	flavin adenine dinucleotide binding
D3Z87_13445	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z87_13455	COG1393	Belongs to the ArsC family
D3Z87_13465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z87_13475	COG0011	TIGRFAM Protein of
D3Z87_13485	COG2866	Carboxypeptidase
D3Z87_13490	COG1368	sulfuric ester hydrolase activity
D3Z87_13495	COG1940	carbohydrate kinase activity
D3Z87_13500	COG4483	Protein conserved in bacteria
D3Z87_13505	COG0705	Rhomboid family
D3Z87_13505	COG0457	Tetratricopeptide repeat
D3Z87_13515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D3Z87_13520	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3Z87_13525	COG0438	transferase activity, transferring glycosyl groups
D3Z87_13540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D3Z87_13545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3Z87_13550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3Z87_13555	COG0581	inorganic phosphate transmembrane transporter activity
D3Z87_13560	COG0573	inorganic phosphate transmembrane transporter activity
D3Z87_13565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3Z87_13575	COG0477	Major facilitator Superfamily
D3Z87_13580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D3Z87_13585	COG2839	Protein conserved in bacteria
D3Z87_13590	COG5521	maltodextrose utilization protein MalA
D3Z87_13600	COG1388	LysM domain
D3Z87_13605	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D3Z87_13610	COG4709	membrane
D3Z87_13615	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D3Z87_13620	COG0735	belongs to the Fur family
D3Z87_13625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z87_13635	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D3Z87_13640	COG0513	Belongs to the DEAD box helicase family
D3Z87_13650	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D3Z87_13655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D3Z87_13660	COG2384	SAM-dependent methyltransferase
D3Z87_13665	COG2010	Cytochrome c
D3Z87_13675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3Z87_13680	COG0358	DNA primase activity
D3Z87_13685	COG1671	Belongs to the UPF0178 family
D3Z87_13690	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D3Z87_13695	COG0517	IMP dehydrogenase activity
D3Z87_13700	COG0751	glycine-tRNA ligase activity
D3Z87_13705	COG0752	glycyl-tRNA synthetase alpha subunit
D3Z87_13710	COG1381	Involved in DNA repair and RecF pathway recombination
D3Z87_13720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D3Z87_13725	COG0295	cytidine deaminase activity
D3Z87_13730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D3Z87_13735	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D3Z87_13740	COG1480	7TM receptor with intracellular HD hydrolase
D3Z87_13745	COG1702	phosphate starvation-inducible protein PhoH
D3Z87_13750	COG0561	phosphatase activity
D3Z87_13765	COG4864	UPF0365 protein
D3Z87_13770	COG1030	water channel activity
D3Z87_13775	COG1610	YqeY-like protein
D3Z87_13780	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D3Z87_13785	COG1283	sodium-dependent phosphate transmembrane transporter activity
D3Z87_13790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3Z87_13795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D3Z87_13800	COG2264	protein methyltransferase activity
D3Z87_13805	COG0484	heat shock protein binding
D3Z87_13810	COG0443	Heat shock 70 kDa protein
D3Z87_13815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D3Z87_13820	COG1420	regulation of RNA biosynthetic process
D3Z87_13825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3Z87_13830	COG0481	GTPase activity
D3Z87_13840	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z87_13845	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D3Z87_13850	COG0268	Binds directly to 16S ribosomal RNA
D3Z87_13855	COG1466	dna polymerase III delta subunit
D3Z87_13865	COG0658	competence protein
D3Z87_13865	COG2333	competence protein COMEC
D3Z87_13870	COG2131	deaminase
D3Z87_13875	COG1596	polysaccharide export
D3Z87_13875	COG1555	photosystem II stabilization
D3Z87_13880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3Z87_13885	COG2226	methyltransferase
D3Z87_13890	COG0799	negative regulation of ribosome biogenesis
D3Z87_13895	COG1713	HD superfamily hydrolase involved in NAD metabolism
D3Z87_13900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D3Z87_13905	COG1534	Rna-binding protein
D3Z87_13910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D3Z87_13915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D3Z87_13920	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D3Z87_13930	COG2755	lipolytic protein G-D-S-L family
D3Z87_13935	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_13935	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3Z87_13940	COG0398	Pfam SNARE associated Golgi protein
D3Z87_13945	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D3Z87_13955	COG3209	COG3209 Rhs family protein
D3Z87_13965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3Z87_13975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3Z87_13980	COG0798	PFAM Bile acid sodium symporter
D3Z87_13985	COG0346	lactoylglutathione lyase activity
D3Z87_13990	COG0640	Transcriptional regulator
D3Z87_13995	COG3403	YqcI/YcgG family
D3Z87_14000	COG0457	Tetratricopeptide repeat
D3Z87_14015	COG5444	nuclease activity
D3Z87_14035	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3Z87_14035	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_14040	COG4824	toxin secretion phage lysis holin
D3Z87_14070	COG3778	Protein conserved in bacteria
D3Z87_14075	COG3299	homolog of phage Mu protein gp47
D3Z87_14080	COG3628	GPW Gp25 family protein
D3Z87_14090	COG4193	domain, Protein
D3Z87_14095	COG1652	LysM domain
D3Z87_14100	COG5280	Phage tail tape measure protein TP901
D3Z87_14100	COG3953	SLT domain
D3Z87_14165	COG4653	Phage capsid family
D3Z87_14170	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D3Z87_14180	COG2369	cell adhesion
D3Z87_14185	COG5518	Phage portal protein
D3Z87_14190	COG1783	phage Terminase large subunit
D3Z87_14195	COG5484	DNA packaging
D3Z87_14205	COG3677	Transposase
D3Z87_14220	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D3Z87_14230	COG1484	DNA-dependent DNA replication
D3Z87_14235	COG3935	DnaD domain protein
D3Z87_14240	COG3723	Recombinational DNA repair protein, rece pathway
D3Z87_14245	COG5377	YqaJ viral recombinase family
D3Z87_14270	COG1476	TRANSCRIPTIONal
D3Z87_14275	COG3620	sequence-specific DNA binding
D3Z87_14285	COG0563	adenylate kinase activity
D3Z87_14290	COG2856	Zn peptidase
D3Z87_14310	COG3223	Belongs to the PsiE family
D3Z87_14315	COG5002	protein histidine kinase activity
D3Z87_14315	COG0642	Histidine kinase
D3Z87_14320	COG0745	RESPONSE REGULATOR receiver
D3Z87_14325	COG2311	Membrane
D3Z87_14330	COG0454	-acetyltransferase
D3Z87_14335	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3Z87_14345	COG0730	response to heat
D3Z87_14350	COG0425	Belongs to the sulfur carrier protein TusA family
D3Z87_14355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3Z87_14355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z87_14365	COG0425	Belongs to the sulfur carrier protein TusA family
D3Z87_14365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3Z87_14375	COG2210	Belongs to the sulfur carrier protein TusA family
D3Z87_14380	COG1937	Protein conserved in bacteria
D3Z87_14395	COG0662	Cupin 2, conserved barrel domain protein
D3Z87_14410	COG4978	Transcriptional regulator
D3Z87_14410	COG0789	Transcriptional regulator
D3Z87_14415	COG2814	Major facilitator Superfamily
D3Z87_14420	COG0456	acetyltransferase
D3Z87_14425	COG1253	flavin adenine dinucleotide binding
D3Z87_14435	COG0697	spore germination
D3Z87_14440	COG0583	DNA-binding transcription factor activity
D3Z87_14445	COG2072	flavoprotein involved in K transport
D3Z87_14450	COG1230	cation diffusion facilitator family transporter
D3Z87_14455	COG1942	4-Oxalocrotonate Tautomerase
D3Z87_14460	COG0583	DNA-binding transcription factor activity
D3Z87_14470	COG1114	Component of the transport system for branched-chain amino acids
D3Z87_14475	COG1687	branched-chain amino acid
D3Z87_14480	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D3Z87_14485	COG1522	sequence-specific DNA binding
D3Z87_14490	COG2732	(Barnase) inhibitor
D3Z87_14495	COG2124	cytochrome p450
D3Z87_14505	COG1335	isochorismatase
D3Z87_14520	COG2318	DinB family
D3Z87_14530	COG2070	2-Nitropropane dioxygenase
D3Z87_14545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D3Z87_14560	COG3443	Belongs to the bacterial solute-binding protein 9 family
D3Z87_14565	COG1595	DNA-templated transcription, initiation
D3Z87_14570	COG0667	Aldo Keto reductase
D3Z87_14575	COG2851	Citrate transporter
D3Z87_14580	COG0583	DNA-binding transcription factor activity
D3Z87_14585	COG2828	Protein conserved in bacteria
D3Z87_14590	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_14595	COG5566	PFAM Mor transcription activator
D3Z87_14600	COG0596	Alpha beta hydrolase
D3Z87_14605	COG4991	sh3 domain protein
D3Z87_14610	COG4991	sh3 domain protein
D3Z87_14615	COG0346	lactoylglutathione lyase activity
D3Z87_14625	COG5577	PFAM Coat F domain
D3Z87_14630	COG1063	alcohol dehydrogenase
D3Z87_14640	COG5577	PFAM Coat F domain
D3Z87_14645	COG0789	Transcriptional regulator
D3Z87_14655	COG1064	alcohol dehydrogenase
D3Z87_14660	COG0693	protein deglycase activity
D3Z87_14665	COG1621	beta-fructofuranosidase activity
D3Z87_14670	COG3716	PTS system mannose fructose sorbose family IID component
D3Z87_14675	COG3715	PTS system
D3Z87_14680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_14685	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z87_14690	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D3Z87_14690	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D3Z87_14695	COG1113	amino acid transport
D3Z87_14700	COG1280	lysine exporter protein (LysE YggA)
D3Z87_14705	COG1378	Sugar-specific transcriptional regulator TrmB
D3Z87_14710	COG1595	DNA-templated transcription, initiation
D3Z87_14720	COG2755	lipolytic protein G-D-S-L family
D3Z87_14720	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D3Z87_14730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3Z87_14730	COG2124	cytochrome p450
D3Z87_14735	COG1309	transcriptional regulator
D3Z87_14740	COG2226	methyltransferase
D3Z87_14750	COG2116	formate transmembrane transporter activity
D3Z87_14755	COG5609	conserved protein (DUF2294)
D3Z87_14760	COG3383	formate dehydrogenase (NAD+) activity
D3Z87_14765	COG2427	Protein of unknown function (DUF1641)
D3Z87_14775	COG0626	cystathionine gamma-synthase activity
D3Z87_14780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3Z87_14785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D3Z87_14790	COG2226	methyltransferase
D3Z87_14805	COG0768	penicillin binding
D3Z87_14810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D3Z87_14815	COG0572	uridine kinase
D3Z87_14835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D3Z87_14840	COG3906	Belongs to the UPF0473 family
D3Z87_14845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D3Z87_14850	COG4472	Bacterial protein of unknown function (DUF965)
D3Z87_14855	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D3Z87_14860	COG0628	permease
D3Z87_14865	COG1126	abc transporter atp-binding protein
D3Z87_14870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z87_14875	COG0765	amino acid transport
D3Z87_14880	COG0765	amino acid transport
D3Z87_14895	COG3881	PFAM PRC-barrel domain
D3Z87_14900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D3Z87_14905	COG0457	Tetratricopeptide repeat
D3Z87_14910	COG0482	sulfurtransferase activity
D3Z87_14915	COG1104	cysteine desulfurase activity
D3Z87_14920	COG1959	2 iron, 2 sulfur cluster binding
D3Z87_14925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D3Z87_14930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D3Z87_14940	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D3Z87_14945	COG0124	histidyl-tRNA synthetase
D3Z87_14955	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z87_14955	COG3103	Sh3 type 3 domain protein
D3Z87_14955	COG4991	sh3 domain protein
D3Z87_14960	COG1490	D-aminoacyl-tRNA deacylase activity
D3Z87_14965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D3Z87_14970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3Z87_14975	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D3Z87_14975	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3Z87_14980	COG5416	Lipopolysaccharide assembly protein A domain
D3Z87_14985	COG0490	domain, Protein
D3Z87_14990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3Z87_14990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3Z87_15000	COG2244	polysaccharide biosynthetic process
D3Z87_15005	COG2323	membrane
D3Z87_15015	COG1862	Preprotein translocase
D3Z87_15020	COG0343	queuine tRNA-ribosyltransferase activity
D3Z87_15025	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D3Z87_15035	COG2255	four-way junction helicase activity
D3Z87_15040	COG0632	four-way junction helicase activity
D3Z87_15050	COG2814	Major facilitator Superfamily
D3Z87_15055	COG0673	inositol 2-dehydrogenase activity
D3Z87_15060	COG2112	serine threonine protein kinase
D3Z87_15075	COG1115	amino acid carrier protein
D3Z87_15080	COG0217	transcriptional regulatory protein
D3Z87_15090	COG1388	LysM domain
D3Z87_15095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D3Z87_15100	COG0157	Belongs to the NadC ModD family
D3Z87_15105	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D3Z87_15110	COG1104	cysteine desulfurase activity
D3Z87_15115	COG1827	regulation of RNA biosynthetic process
D3Z87_15120	COG0077	Prephenate dehydratase
D3Z87_15125	COG4492	Belongs to the UPF0735 family
D3Z87_15130	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D3Z87_15135	COG3290	protein histidine kinase activity
D3Z87_15140	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D3Z87_15145	COG2868	ribosomal protein
D3Z87_15150	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D3Z87_15155	COG1994	Peptidase M50
D3Z87_15160	COG0739	heme binding
D3Z87_15165	COG2894	cell division
D3Z87_15170	COG0850	regulation of cytokinetic process
D3Z87_15175	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D3Z87_15180	COG1792	Involved in formation and maintenance of cell shape
D3Z87_15190	COG2003	Belongs to the UPF0758 family
D3Z87_15195	COG0424	maF-like protein
D3Z87_15205	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D3Z87_15210	COG0285	dihydrofolate synthase activity
D3Z87_15215	COG0525	valine-tRNA ligase activity
D3Z87_15225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3Z87_15230	COG1388	LysM domain
D3Z87_15235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D3Z87_15240	COG0113	porphobilinogen synthase activity
D3Z87_15245	COG1587	Uroporphyrinogen-III synthase
D3Z87_15250	COG0181	hydroxymethylbilane synthase activity
D3Z87_15255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3Z87_15260	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D3Z87_15270	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D3Z87_15275	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D3Z87_15280	COG1067	ATP-dependent peptidase activity
D3Z87_15280	COG0470	DNA polymerase III
D3Z87_15285	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D3Z87_15290	COG0544	peptidyl-prolyl cis-trans isomerase activity
D3Z87_15295	COG0457	Tetratricopeptide repeat
D3Z87_15295	COG1477	protein flavinylation
D3Z87_15300	COG0066	3-isopropylmalate dehydratase activity
D3Z87_15305	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D3Z87_15310	COG0473	3-isopropylmalate dehydrogenase activity
D3Z87_15315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D3Z87_15320	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D3Z87_15325	COG0440	acetolactate synthase activity
D3Z87_15330	COG0028	Belongs to the TPP enzyme family
D3Z87_15340	COG0454	-acetyltransferase
D3Z87_15345	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D3Z87_15355	COG0622	Phosphoesterase
D3Z87_15360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D3Z87_15365	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D3Z87_15370	COG5401	PFAM Sporulation and spore germination
D3Z87_15375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D3Z87_15380	COG1846	Transcriptional regulator
D3Z87_15385	COG2197	response regulator
D3Z87_15390	COG0824	Thioesterase
D3Z87_15395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D3Z87_15400	COG1053	succinate dehydrogenase
D3Z87_15405	COG2009	succinate dehydrogenase
D3Z87_15410	COG1719	4-vinyl reductase, 4VR
D3Z87_15415	COG0527	aspartate kinase activity
D3Z87_15425	COG0322	excinuclease ABC activity
D3Z87_15430	COG3118	belongs to the thioredoxin family
D3Z87_15440	COG3534	alpha-L-arabinofuranosidase
D3Z87_15445	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D3Z87_15450	COG2086	electron transfer activity
D3Z87_15455	COG1024	Enoyl-CoA hydratase
D3Z87_15460	COG1309	transcriptional regulator
D3Z87_15465	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z87_15470	COG3766	membrane
D3Z87_15475	COG1193	negative regulation of DNA recombination
D3Z87_15480	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D3Z87_15480	COG1796	DNA polymerase
D3Z87_15485	COG1286	toxin biosynthetic process
D3Z87_15490	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D3Z87_15495	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D3Z87_15500	COG0072	phenylalanine-tRNA ligase activity
D3Z87_15500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3Z87_15505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D3Z87_15515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3Z87_15525	COG3835	regulator
D3Z87_15530	COG0277	FAD linked oxidase domain protein
D3Z87_15535	COG0247	lactate metabolic process
D3Z87_15540	COG0346	lactoylglutathione lyase activity
D3Z87_15545	COG1966	Carbon starvation protein
D3Z87_15550	COG3534	alpha-L-arabinofuranosidase
D3Z87_15555	COG0395	ABC-type sugar transport system, permease component
D3Z87_15560	COG1175	transmembrane transport
D3Z87_15565	COG1653	transport
D3Z87_15570	COG0371	Dehydrogenase
D3Z87_15575	COG0647	UMP catabolic process
D3Z87_15580	COG0235	Class ii aldolase
D3Z87_15585	COG1069	ribulokinase activity
D3Z87_15590	COG2160	L-arabinose isomerase activity
D3Z87_15595	COG3507	Belongs to the glycosyl hydrolase 43 family
D3Z87_15600	COG1363	Peptidase, m42
D3Z87_15610	COG3326	Membrane
D3Z87_15615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D3Z87_15620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D3Z87_15625	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D3Z87_15635	COG1346	cytolysis
D3Z87_15640	COG1380	Effector of murein hydrolase LrgA
D3Z87_15645	COG3279	Response regulator of the LytR AlgR family
D3Z87_15650	COG3275	phosphorelay sensor kinase activity
D3Z87_15660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D3Z87_15670	COG0398	Pfam SNARE associated Golgi protein
D3Z87_15675	COG1484	DNA-dependent DNA replication
D3Z87_15680	COG3611	Membrane attachment protein
D3Z87_15685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D3Z87_15690	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D3Z87_15695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3Z87_15700	COG1733	regulation of RNA biosynthetic process
D3Z87_15705	COG2814	Major facilitator Superfamily
D3Z87_15710	COG0656	L-ascorbic acid biosynthetic process
D3Z87_15715	COG0237	dephospho-CoA kinase activity
D3Z87_15720	COG1971	Probably functions as a manganese efflux pump
D3Z87_15725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D3Z87_15730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3Z87_15730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3Z87_15735	COG5002	protein histidine kinase activity
D3Z87_15740	COG0745	RESPONSE REGULATOR receiver
D3Z87_15745	COG0039	L-malate dehydrogenase activity
D3Z87_15750	COG0538	isocitrate dehydrogenase activity
D3Z87_15755	COG0372	Belongs to the citrate synthase family
D3Z87_15760	COG2707	UPF0756 membrane protein
D3Z87_15765	COG0628	permease
D3Z87_15770	COG3030	protein affecting phage T7 exclusion by the F plasmid
D3Z87_15775	COG0469	pyruvate kinase activity
D3Z87_15780	COG0205	6-phosphofructokinase activity
D3Z87_15785	COG0825	malonyl-CoA metabolic process
D3Z87_15790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D3Z87_15795	COG0281	malic enzyme
D3Z87_15800	COG0587	DNA-directed DNA polymerase activity
D3Z87_15820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D3Z87_15830	COG4109	DRTGG domain
D3Z87_15835	COG0730	response to heat
D3Z87_15840	COG1473	amidohydrolase
D3Z87_15845	COG0196	riboflavin kinase activity
D3Z87_15850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z87_15855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D3Z87_15860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z87_15865	COG1126	abc transporter atp-binding protein
D3Z87_15870	COG0765	amino acid transport
D3Z87_15875	COG0765	amino acid transport
D3Z87_15880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z87_15885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z87_15890	COG0454	-acetyltransferase
D3Z87_15895	COG0583	DNA-binding transcription factor activity
D3Z87_15900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D3Z87_15905	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_15915	COG0165	Argininosuccinate lyase
D3Z87_15920	COG0137	argininosuccinate synthase activity
D3Z87_15925	COG0521	Mo-molybdopterin cofactor biosynthetic process
D3Z87_15930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D3Z87_15935	COG0827	DNA restriction-modification system
D3Z87_15940	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D3Z87_15945	COG3874	Sporulation protein YtfJ
D3Z87_15955	COG1714	RDD family
D3Z87_15960	COG0616	signal peptide processing
D3Z87_15965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D3Z87_15970	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D3Z87_15975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3Z87_15985	COG0301	tRNA thio-modification
D3Z87_15990	COG1104	cysteine desulfurase activity
D3Z87_15995	COG1114	Component of the transport system for branched-chain amino acids
D3Z87_16000	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D3Z87_16005	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D3Z87_16010	COG1309	transcriptional regulator
D3Z87_16015	COG1956	GAF domain-containing protein
D3Z87_16020	COG2203	Gaf domain
D3Z87_16020	COG2199	diguanylate cyclase activity
D3Z87_16030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D3Z87_16035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D3Z87_16045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3Z87_16050	COG0454	-acetyltransferase
D3Z87_16055	COG0517	IMP dehydrogenase activity
D3Z87_16060	COG0123	including yeast histone deacetylase and acetoin utilization protein
D3Z87_16065	COG1360	Flagellar Motor Protein
D3Z87_16070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D3Z87_16075	COG1609	Transcriptional regulator
D3Z87_16080	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D3Z87_16080	COG1605	Chorismate mutase
D3Z87_16085	COG3118	belongs to the thioredoxin family
D3Z87_16090	COG4980	gas vesicle protein
D3Z87_16095	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D3Z87_16100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D3Z87_16105	COG1674	ftsk spoiiie
D3Z87_16110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3Z87_16115	COG4848	Belongs to the UPF0354 family
D3Z87_16120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_16130	COG1363	Peptidase, m42
D3Z87_16135	COG5584	Small secreted protein
D3Z87_16140	COG0281	malic enzyme
D3Z87_16145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z87_16150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D3Z87_16160	COG0510	thiamine kinase activity
D3Z87_16165	COG1523	belongs to the glycosyl hydrolase 13 family
D3Z87_16170	COG1597	lipid kinase activity
D3Z87_16180	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D3Z87_16185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3Z87_16190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3Z87_16195	COG2252	PERMEase
D3Z87_16200	COG4473	ABC transporter
D3Z87_16205	COG1131	(ABC) transporter
D3Z87_16210	COG1349	DNA-binding transcription factor activity
D3Z87_16215	COG1187	pseudouridine synthase activity
D3Z87_16220	COG2244	polysaccharide biosynthetic process
D3Z87_16225	COG2081	HI0933 family
D3Z87_16230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3Z87_16240	COG5578	integral membrane protein
D3Z87_16245	COG0673	inositol 2-dehydrogenase activity
D3Z87_16250	COG1653	transport
D3Z87_16255	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D3Z87_16260	COG4209	transmembrane transport
D3Z87_16265	COG2207	Transcriptional regulator
D3Z87_16270	COG1653	transport
D3Z87_16275	COG0395	ABC-type sugar transport system, permease component
D3Z87_16280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3Z87_16285	COG2124	cytochrome p450
D3Z87_16290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D3Z87_16295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D3Z87_16300	COG0156	8-amino-7-oxononanoate synthase activity
D3Z87_16305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3Z87_16310	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
D3Z87_16315	COG1073	alpha beta
D3Z87_16340	COG1486	melibiose metabolic process
D3Z87_16345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3Z87_16350	COG0495	leucyl-tRNA aminoacylation
D3Z87_16360	COG1366	Belongs to the anti-sigma-factor antagonist family
D3Z87_16360	COG2202	Pas domain
D3Z87_16365	COG2814	Major facilitator Superfamily
D3Z87_16370	COG2433	Pfam Transposase IS66
D3Z87_16375	COG0577	efflux transmembrane transporter activity
D3Z87_16380	COG1136	(ABC) transporter
D3Z87_16385	COG2205	protein histidine kinase activity
D3Z87_16390	COG0745	RESPONSE REGULATOR receiver
D3Z87_16395	COG0577	efflux transmembrane transporter activity
D3Z87_16400	COG1136	(ABC) transporter
D3Z87_16415	COG1131	(ABC) transporter
D3Z87_16420	COG1725	Transcriptional regulator
D3Z87_16430	COG1242	4 iron, 4 sulfur cluster binding
D3Z87_16435	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D3Z87_16445	COG2267	carboxylic ester hydrolase activity
D3Z87_16450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D3Z87_16455	COG1113	amino acid transport
D3Z87_16460	COG0367	asparagine synthase
D3Z87_16465	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D3Z87_16470	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D3Z87_16480	COG1506	peptidase
D3Z87_16485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3Z87_16490	COG1116	anion transmembrane transporter activity
D3Z87_16495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3Z87_16500	COG0494	nUDIX hydrolase
D3Z87_16505	COG4824	toxin secretion phage lysis holin
D3Z87_16510	COG0783	Belongs to the Dps family
D3Z87_16525	COG1854	S-ribosylhomocysteine lyase activity
D3Z87_16530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D3Z87_16535	COG0288	reversible hydration of carbon dioxide
D3Z87_16540	COG0254	rRNA binding
D3Z87_16545	COG1271	oxidase subunit
D3Z87_16550	COG1294	oxidase, subunit
D3Z87_16560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3Z87_16565	COG1321	iron dependent repressor
D3Z87_16565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3Z87_16570	COG1121	(ABC) transporter
D3Z87_16575	COG0803	Belongs to the bacterial solute-binding protein 9 family
D3Z87_16585	COG4948	Mandelate Racemase Muconate Lactonizing
D3Z87_16590	COG0318	PFAM AMP-dependent synthetase and ligase
D3Z87_16595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D3Z87_16600	COG0596	Alpha beta hydrolase
D3Z87_16605	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D3Z87_16610	COG1169	isochorismate synthase
D3Z87_16620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3Z87_16625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3Z87_16630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3Z87_16635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3Z87_16640	COG0438	transferase activity, transferring glycosyl groups
D3Z87_16650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3Z87_16655	COG0438	transferase activity, transferring glycosyl groups
D3Z87_16660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3Z87_16665	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D3Z87_16670	COG0058	SHG alpha-glucan phosphorylase activity
D3Z87_16675	COG0297	glycogen (starch) synthase activity
D3Z87_16680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D3Z87_16685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D3Z87_16690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D3Z87_16815	COG3859	Proton-coupled thiamine transporter YuaJ
D3Z87_16820	COG1247	-acetyltransferase
D3Z87_16825	COG2268	Band 7 protein
D3Z87_16830	COG1585	Membrane protein implicated in regulation of membrane protease activity
D3Z87_16835	COG2318	DinB family
D3Z87_16845	COG1454	alcohol dehydrogenase
D3Z87_16855	COG1510	regulation of RNA biosynthetic process
D3Z87_16865	COG0569	domain protein
D3Z87_16870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3Z87_16875	COG4682	membrane
D3Z87_16880	COG1705	Flagellar rod assembly protein muramidase FlgJ
D3Z87_16885	COG0477	Major facilitator Superfamily
D3Z87_16890	COG5553	Cysteine dioxygenase type I
D3Z87_16900	COG1968	undecaprenyl-diphosphatase activity
D3Z87_16905	COG0628	permease
D3Z87_16910	COG0673	inositol 2-dehydrogenase activity
D3Z87_16915	COG4806	L-rhamnose isomerase
D3Z87_16920	COG3254	rhamnose metabolic process
D3Z87_16925	COG1070	Carbohydrate kinase
D3Z87_16930	COG1349	DNA-binding transcription factor activity
D3Z87_16935	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_16935	COG3347	Dehydrogenase
D3Z87_16945	COG0840	transmembrane signaling receptor activity
D3Z87_16950	COG0840	transmembrane signaling receptor activity
D3Z87_16955	COG0840	transmembrane signaling receptor activity
D3Z87_16960	COG0840	transmembrane signaling receptor activity
D3Z87_16975	COG0432	Pfam Uncharacterised protein family UPF0047
D3Z87_16980	COG0366	Alpha amylase catalytic
D3Z87_16985	COG1253	flavin adenine dinucleotide binding
D3Z87_16990	COG2738	Putative neutral zinc metallopeptidase
D3Z87_17005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3Z87_17020	COG0166	Belongs to the GPI family
D3Z87_17025	COG1979	alcohol dehydrogenase
D3Z87_17030	COG1979	alcohol dehydrogenase
D3Z87_17035	COG2155	Conserved Protein
D3Z87_17040	COG1098	S1 RNA binding domain
D3Z87_17045	COG0436	Aminotransferase
D3Z87_17050	COG1522	sequence-specific DNA binding
D3Z87_17055	COG2267	carboxylic ester hydrolase activity
D3Z87_17065	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D3Z87_17070	COG2205	protein histidine kinase activity
D3Z87_17080	COG5018	Exonuclease
D3Z87_17090	COG2814	Major facilitator Superfamily
D3Z87_17095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3Z87_17100	COG3011	Protein conserved in bacteria
D3Z87_17110	COG3290	protein histidine kinase activity
D3Z87_17115	COG4565	transcriptional regulatory protein
D3Z87_17140	COG3493	citrate carrier protein
D3Z87_17150	COG2111	Na H antiporter
D3Z87_17150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3Z87_17155	COG2111	Na H antiporter
D3Z87_17160	COG1006	Multisubunit Na H antiporter MnhC subunit
D3Z87_17165	COG0651	ATP synthesis coupled electron transport
D3Z87_17170	COG1863	multisubunit Na H antiporter MnhE subunit
D3Z87_17175	COG2212	antiporter activity
D3Z87_17180	COG1320	monovalent cation:proton antiporter activity
D3Z87_17185	COG2050	protein possibly involved in aromatic compounds catabolism
D3Z87_17190	COG2197	response regulator
D3Z87_17195	COG4585	Histidine kinase
D3Z87_17205	COG0142	geranyltranstransferase activity
D3Z87_17220	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D3Z87_17225	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D3Z87_17230	COG1335	isochorismatase
D3Z87_17235	COG5506	Protein of unknown function (DUF1694)
D3Z87_17250	COG0628	permease
D3Z87_17265	COG1418	mRNA catabolic process
D3Z87_17270	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_17280	COG1511	domain protein
D3Z87_17285	COG0433	COG0433 Predicted ATPase
D3Z87_17285	COG1674	ftsk spoiiie
D3Z87_17290	COG4499	WXG100 protein secretion system (Wss), protein YukC
D3Z87_17295	COG5417	Belongs to the EsaB family
D3Z87_17300	COG4842	Belongs to the WXG100 family
D3Z87_17305	COG2508	Transcriptional regulator
D3Z87_17305	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D3Z87_17310	COG0686	Belongs to the AlaDH PNT family
D3Z87_17315	COG5634	Uncharacterized conserved protein (DUF2278)
D3Z87_17320	COG3251	PFAM MbtH domain protein
D3Z87_17325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_17330	COG1535	isochorismatase
D3Z87_17330	COG3433	isochorismatase activity
D3Z87_17335	COG1021	2,3-dihydroxybenzoate-AMP ligase
D3Z87_17340	COG1169	isochorismate synthase
D3Z87_17345	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_17350	COG2819	hydrolase of the alpha beta superfamily
D3Z87_17355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D3Z87_17360	COG1268	BioY protein
D3Z87_17365	COG2056	Na+-H+ antiporter family
D3Z87_17370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D3Z87_17375	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D3Z87_17380	COG3584	3D domain protein
D3Z87_17395	COG1252	NADH dehydrogenase
D3Z87_17400	COG0492	ferredoxin-NADP+ reductase activity
D3Z87_17410	COG0516	GMP reductase activity
D3Z87_17415	COG2808	Putative FMN-binding domain
D3Z87_17420	COG0456	acetyltransferase
D3Z87_17425	COG0316	Belongs to the HesB IscA family
D3Z87_17430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D3Z87_17435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3Z87_17440	COG4844	belongs to the
D3Z87_17445	COG1252	NADH dehydrogenase
D3Z87_17450	COG4837	Protein of unknown function (DUF1462)
D3Z87_17455	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D3Z87_17460	COG4946	Tricorn protease homolog
D3Z87_17460	COG0823	Involved in the tonB-independent uptake of proteins
D3Z87_17460	COG1506	peptidase
D3Z87_17465	COG0083	homoserine kinase activity
D3Z87_17470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D3Z87_17475	COG0460	homoserine dehydrogenase
D3Z87_17480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3Z87_17485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D3Z87_17490	COG0647	UMP catabolic process
D3Z87_17495	COG2445	Protein of unknown function DUF86
D3Z87_17500	COG4470	Protein conserved in bacteria
D3Z87_17510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D3Z87_17515	COG0739	heme binding
D3Z87_17525	COG3377	Domain of unknown function (DUF1805)
D3Z87_17530	COG0737	Belongs to the 5'-nucleotidase family
D3Z87_17535	COG0730	response to heat
D3Z87_17540	COG1801	Protein of unknown function DUF72
D3Z87_17550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3Z87_17555	COG2508	Transcriptional regulator
D3Z87_17560	COG2233	PERMEase
D3Z87_17565	COG2233	PERMEase
D3Z87_17570	COG3648	Uricase
D3Z87_17570	COG3195	allantoin biosynthetic process
D3Z87_17575	COG2351	hydroxyisourate hydrolase activity
D3Z87_17585	COG2080	2 iron, 2 sulfur cluster binding
D3Z87_17590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D3Z87_17595	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D3Z87_17600	COG2068	MobA-Related Protein
D3Z87_17605	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D3Z87_17610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D3Z87_17615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3Z87_17620	COG2356	endonuclease I
D3Z87_17625	COG3842	ATPase activity
D3Z87_17630	COG2188	Transcriptional regulator
D3Z87_17635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3Z87_17640	COG0395	ABC-type sugar transport system, permease component
D3Z87_17645	COG1175	transmembrane transport
D3Z87_17650	COG1653	transport
D3Z87_17655	COG2222	sugar isomerase
D3Z87_17660	COG0322	excinuclease ABC activity
D3Z87_17665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3Z87_17680	COG0346	lactoylglutathione lyase activity
D3Z87_17685	COG0640	Transcriptional regulator
D3Z87_17690	COG0719	Fe-S assembly protein
D3Z87_17695	COG0822	iron-sulfur transferase activity
D3Z87_17700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3Z87_17705	COG0719	Fe-S assembly protein
D3Z87_17710	COG0396	ATPase activity
D3Z87_17725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3Z87_17730	COG1464	Belongs to the NlpA lipoprotein family
D3Z87_17735	COG2011	ABC-type metal ion transport system permease component
D3Z87_17740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D3Z87_17750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3Z87_17755	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D3Z87_17765	COG0509	glycine decarboxylation via glycine cleavage system
D3Z87_17770	COG1393	Belongs to the ArsC family
D3Z87_17775	COG1960	acyl-CoA dehydrogenase activity
D3Z87_17780	COG0183	Belongs to the thiolase family
D3Z87_17785	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3Z87_17785	COG1024	Enoyl-CoA hydratase
D3Z87_17795	COG0506	proline dehydrogenase activity
D3Z87_17805	COG5577	PFAM Coat F domain
D3Z87_17810	COG1846	Transcriptional regulator
D3Z87_17815	COG0477	Major facilitator Superfamily
D3Z87_17820	COG1942	4-Oxalocrotonate Tautomerase
D3Z87_17830	COG0583	DNA-binding transcription factor activity
D3Z87_17840	COG1120	ATPase activity
D3Z87_17855	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_17860	COG0783	Belongs to the Dps family
D3Z87_17865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3Z87_17870	COG0745	RESPONSE REGULATOR receiver
D3Z87_17875	COG2770	Histidine kinase
D3Z87_17875	COG2205	protein histidine kinase activity
D3Z87_17885	COG1309	transcriptional regulator
D3Z87_17890	COG0114	fumarate hydratase activity
D3Z87_17900	COG0697	spore germination
D3Z87_17905	COG0814	amino acid
D3Z87_17915	COG2197	response regulator
D3Z87_17920	COG4585	Histidine kinase
D3Z87_17925	COG4758	membrane
D3Z87_17930	COG3595	metallopeptidase activity
D3Z87_17935	COG1842	Phage shock protein A
D3Z87_17940	COG4758	membrane
D3Z87_17945	COG2814	Major facilitator Superfamily
D3Z87_17950	COG2096	Adenosyltransferase
D3Z87_17955	COG1120	ATPase activity
D3Z87_17960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z87_17965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z87_17970	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_17975	COG3386	PFAM SMP-30 Gluconolaconase
D3Z87_17980	COG2205	protein histidine kinase activity
D3Z87_17985	COG0745	RESPONSE REGULATOR receiver
D3Z87_17995	COG1191	sigma factor activity
D3Z87_18005	COG2140	Oxalate decarboxylase
D3Z87_18015	COG0577	efflux transmembrane transporter activity
D3Z87_18020	COG1136	(ABC) transporter
D3Z87_18025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3Z87_18030	COG1120	ATPase activity
D3Z87_18035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z87_18040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3Z87_18045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z87_18055	COG0531	amino acid
D3Z87_18070	COG1988	membrane-bound metal-dependent
D3Z87_18075	COG1368	sulfuric ester hydrolase activity
D3Z87_18080	COG1910	domain protein
D3Z87_18085	COG0725	ABC transporter, periplasmic molybdate-binding protein
D3Z87_18090	COG4149	molybdate abc transporter
D3Z87_18095	COG0656	L-ascorbic acid biosynthetic process
D3Z87_18105	COG0025	NhaP-type Na H and K H
D3Z87_18110	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3Z87_18115	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3Z87_18120	COG3973	AAA domain
D3Z87_18125	COG2860	membrane
D3Z87_18130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D3Z87_18135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D3Z87_18140	COG2217	Heavy metal translocating P-type atpase
D3Z87_18145	COG2217	Heavy metal translocating P-type atpase
D3Z87_18150	COG2608	mercury ion transmembrane transporter activity
D3Z87_18155	COG1937	Protein conserved in bacteria
D3Z87_18160	COG0673	inositol 2-dehydrogenase activity
D3Z87_18165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D3Z87_18170	COG1289	transmembrane transporter activity
D3Z87_18180	COG2076	Multidrug Resistance protein
D3Z87_18185	COG1309	transcriptional regulator
D3Z87_18190	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_18200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D3Z87_18205	COG0557	exoribonuclease II activity
D3Z87_18210	COG1647	Serine aminopeptidase, S33
D3Z87_18215	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D3Z87_18220	COG0596	Alpha beta hydrolase
D3Z87_18225	COG1476	TRANSCRIPTIONal
D3Z87_18230	COG1396	sequence-specific DNA binding
D3Z87_18235	COG1396	sequence-specific DNA binding
D3Z87_18240	COG1733	regulation of RNA biosynthetic process
D3Z87_18245	COG0840	transmembrane signaling receptor activity
D3Z87_18250	COG1174	glycine betaine transport
D3Z87_18255	COG1732	Glycine betaine
D3Z87_18260	COG1174	glycine betaine transport
D3Z87_18265	COG0517	IMP dehydrogenase activity
D3Z87_18265	COG1125	glycine betaine transport
D3Z87_18270	COG1510	regulation of RNA biosynthetic process
D3Z87_18290	COG5658	integral membrane protein
D3Z87_18295	COG0640	Transcriptional regulator
D3Z87_18300	COG1174	glycine betaine transport
D3Z87_18305	COG1732	Glycine betaine
D3Z87_18310	COG1174	glycine betaine transport
D3Z87_18315	COG1125	glycine betaine transport
D3Z87_18315	COG0517	IMP dehydrogenase activity
D3Z87_18320	COG1510	regulation of RNA biosynthetic process
D3Z87_18325	COG2095	MarC family integral membrane protein
D3Z87_18335	COG3064	Membrane
D3Z87_18340	COG4640	response to antibiotic
D3Z87_18345	COG0456	acetyltransferase
D3Z87_18350	COG0148	phosphopyruvate hydratase activity
D3Z87_18355	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D3Z87_18360	COG0149	triose-phosphate isomerase activity
D3Z87_18365	COG0126	phosphoglycerate kinase activity
D3Z87_18370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3Z87_18375	COG2390	Transcriptional regulator
D3Z87_18380	COG2814	Major facilitator Superfamily
D3Z87_18385	COG1609	Transcriptional regulator
D3Z87_18390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z87_18400	COG0583	DNA-binding transcription factor activity
D3Z87_18405	COG0697	spore germination
D3Z87_18410	COG1113	amino acid transport
D3Z87_18415	COG3858	chitin binding
D3Z87_18420	COG1556	Lactate utilization protein
D3Z87_18425	COG1139	Iron-sulfur cluster binding protein
D3Z87_18430	COG0247	lactate metabolic process
D3Z87_18435	COG2197	response regulator
D3Z87_18440	COG4585	Histidine kinase
D3Z87_18445	COG0842	Transport permease protein
D3Z87_18450	COG1131	(ABC) transporter
D3Z87_18455	COG0596	Alpha beta hydrolase
D3Z87_18460	COG2208	phosphoserine phosphatase activity
D3Z87_18465	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D3Z87_18470	COG1874	Beta-galactosidase
D3Z87_18475	COG3833	ABC-type maltose transport systems, permease component
D3Z87_18480	COG1175	transmembrane transport
D3Z87_18485	COG2182	Extracellular solute-binding protein
D3Z87_18490	COG1609	Transcriptional regulator
D3Z87_18495	COG2186	Transcriptional regulator
D3Z87_18500	COG1620	l-lactate permease
D3Z87_18505	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D3Z87_18515	COG5039	Polysaccharide pyruvyl transferase
D3Z87_18520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3Z87_18525	COG0110	maltose O-acetyltransferase activity
D3Z87_18530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D3Z87_18535	COG2244	polysaccharide biosynthetic process
D3Z87_18540	COG1216	Glycosyl transferase, family 2
D3Z87_18545	COG5039	Polysaccharide pyruvyl transferase
D3Z87_18550	COG1216	Glycosyl transferase, family 2
D3Z87_18560	COG0438	transferase activity, transferring glycosyl groups
D3Z87_18565	COG1215	transferase activity, transferring glycosyl groups
D3Z87_18570	COG0438	transferase activity, transferring glycosyl groups
D3Z87_18575	COG1086	Polysaccharide biosynthesis protein
D3Z87_18580	COG0489	protein tyrosine kinase activity
D3Z87_18585	COG3944	biosynthesis protein
D3Z87_18590	COG1396	sequence-specific DNA binding
D3Z87_18595	COG2272	Belongs to the type-B carboxylesterase lipase family
D3Z87_18605	COG3479	Phenolic acid decarboxylase
D3Z87_18620	COG1794	racemase activity, acting on amino acids and derivatives
D3Z87_18625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3Z87_18630	COG1621	beta-fructofuranosidase activity
D3Z87_18635	COG1621	beta-fructofuranosidase activity
D3Z87_18640	COG0531	amino acid
D3Z87_18645	COG1309	transcriptional regulator
D3Z87_18650	COG2076	Multidrug Resistance protein
D3Z87_18655	COG2076	Multidrug Resistance protein
D3Z87_18665	COG0277	FAD linked oxidase domain protein
D3Z87_18670	COG3621	Patatin-like phospholipase
D3Z87_18680	COG0740	serine-type endopeptidase activity
D3Z87_18685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3Z87_18690	COG0366	Alpha amylase catalytic
D3Z87_18695	COG1554	hydrolase, family 65, central catalytic
D3Z87_18700	COG5521	maltodextrose utilization protein MalA
D3Z87_18705	COG3833	ABC-type maltose transport systems, permease component
D3Z87_18710	COG1175	transmembrane transport
D3Z87_18715	COG2182	Extracellular solute-binding protein
D3Z87_18720	COG0366	Alpha amylase catalytic
D3Z87_18725	COG1609	Transcriptional regulator
D3Z87_18730	COG1611	Belongs to the LOG family
D3Z87_18735	COG1694	Mazg nucleotide pyrophosphohydrolase
D3Z87_18740	COG0659	secondary active sulfate transmembrane transporter activity
D3Z87_18745	COG0288	reversible hydration of carbon dioxide
D3Z87_18755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3Z87_18760	COG0577	efflux transmembrane transporter activity
D3Z87_18765	COG1136	(ABC) transporter
D3Z87_18770	COG5002	protein histidine kinase activity
D3Z87_18775	COG0745	RESPONSE REGULATOR receiver
D3Z87_18785	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D3Z87_18790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z87_18795	COG1481	regulation of sporulation
D3Z87_18800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D3Z87_18805	COG1660	Displays ATPase and GTPase activities
D3Z87_18810	COG1051	belongs to the nudix hydrolase family
D3Z87_18815	COG0492	ferredoxin-NADP+ reductase activity
D3Z87_18820	COG0791	NLP P60 protein
D3Z87_18820	COG3883	PFAM NLP P60 protein
D3Z87_18825	COG0457	Tetratricopeptide repeat
D3Z87_18830	COG1132	(ABC) transporter
D3Z87_18850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D3Z87_18850	COG0140	phosphoribosyl-ATP diphosphatase activity
D3Z87_18855	COG0107	imidazoleglycerol-phosphate synthase activity
D3Z87_18860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D3Z87_18865	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D3Z87_18870	COG0131	Imidazoleglycerol-phosphate dehydratase
D3Z87_18875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D3Z87_18880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D3Z87_18885	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D3Z87_18890	COG4990	cell redox homeostasis
D3Z87_18895	COG5297	Belongs to the glycosyl hydrolase family 6
D3Z87_18900	COG0110	maltose O-acetyltransferase activity
D3Z87_18905	COG0546	phosphoglycolate phosphatase activity
D3Z87_18910	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D3Z87_18915	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D3Z87_18920	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D3Z87_18925	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D3Z87_18930	COG0363	glucosamine-6-phosphate deaminase activity
D3Z87_18940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3Z87_18945	COG1846	Transcriptional regulator
D3Z87_18950	COG2124	cytochrome p450
D3Z87_18960	COG1846	Transcriptional regulator
D3Z87_18965	COG2814	Major facilitator Superfamily
D3Z87_18970	COG1950	PFAM Membrane protein of
D3Z87_18975	COG1983	PspC domain protein
D3Z87_18980	COG3595	metallopeptidase activity
D3Z87_19000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D3Z87_19005	COG0556	nucleotide-excision repair
D3Z87_19010	COG4897	Protein conserved in bacteria
D3Z87_19015	COG3848	Pyruvate phosphate dikinase
D3Z87_19015	COG0574	Belongs to the PEP-utilizing enzyme family
D3Z87_19020	COG1309	transcriptional regulator
D3Z87_19025	COG2814	Major facilitator Superfamily
D3Z87_19030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3Z87_19040	COG3409	Peptidoglycan-binding domain 1 protein
D3Z87_19040	COG0793	Belongs to the peptidase S41A family
D3Z87_19045	COG2177	Part of the ABC transporter FtsEX involved in
D3Z87_19050	COG2884	Cell division ATP-binding protein ftsE
D3Z87_19055	COG2010	Cytochrome c
D3Z87_19060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z87_19070	COG0653	protein targeting
D3Z87_19075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D3Z87_19090	COG1516	flagellar protein fliS
D3Z87_19095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D3Z87_19100	COG1334	flagellar protein FlaG
D3Z87_19105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3Z87_19110	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D3Z87_19115	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D3Z87_19125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3Z87_19130	COG4786	Flagellar basal body rod
D3Z87_19130	COG1256	bacterial-type flagellum assembly
D3Z87_19135	COG3418	PFAM FlgN family protein
D3Z87_19140	COG2747	anti-sigma28 factor FlgM
D3Z87_19150	COG1040	competence protein
D3Z87_19160	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D3Z87_19165	COG1307	EDD domain protein, DegV family
D3Z87_19170	COG2197	response regulator
D3Z87_19175	COG4585	Histidine kinase
D3Z87_19180	COG1739	Uncharacterized protein family UPF0029
D3Z87_19185	COG1316	TRANSCRIPTIONal
D3Z87_19190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3Z87_19195	COG0438	transferase activity, transferring glycosyl groups
D3Z87_19200	COG1215	transferase activity, transferring glycosyl groups
D3Z87_19205	COG3206	protein involved in exopolysaccharide biosynthesis
D3Z87_19210	COG3307	-O-antigen
D3Z87_19215	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3Z87_19220	COG0297	glycogen (starch) synthase activity
D3Z87_19220	COG0438	transferase activity, transferring glycosyl groups
D3Z87_19225	COG2244	polysaccharide biosynthetic process
D3Z87_19235	COG2247	cell wall binding repeat
D3Z87_19235	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3Z87_19240	COG2385	sporulation resulting in formation of a cellular spore
D3Z87_19240	COG2247	cell wall binding repeat
D3Z87_19250	COG1316	TRANSCRIPTIONal
D3Z87_19255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D3Z87_19260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3Z87_19270	COG1215	transferase activity, transferring glycosyl groups
D3Z87_19270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3Z87_19275	COG0463	Glycosyl transferase, family 2
D3Z87_19285	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3Z87_19295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3Z87_19300	COG1134	teichoic acid transport
D3Z87_19305	COG1682	transport, permease protein
D3Z87_19310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3Z87_19315	COG0438	transferase activity, transferring glycosyl groups
D3Z87_19320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D3Z87_19325	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D3Z87_19330	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3Z87_19340	COG4193	domain, Protein
D3Z87_19345	COG1482	cell wall glycoprotein biosynthetic process
D3Z87_19350	COG0697	spore germination
D3Z87_19355	COG0814	amino acid
D3Z87_19365	COG2814	Major facilitator Superfamily
D3Z87_19370	COG1316	TRANSCRIPTIONal
D3Z87_19375	COG0561	phosphatase activity
D3Z87_19380	COG0791	NLP P60 protein
D3Z87_19390	COG2843	Capsule synthesis protein
D3Z87_19400	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D3Z87_19410	COG1609	Transcriptional regulator
D3Z87_19415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3Z87_19420	COG1869	D-ribose catabolic process
D3Z87_19425	COG1129	ABC transporter
D3Z87_19430	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3Z87_19435	COG1879	ABC-type sugar transport system periplasmic component
D3Z87_19440	COG3103	Sh3 type 3 domain protein
D3Z87_19450	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3Z87_19455	COG3527	Alpha-acetolactate decarboxylase
D3Z87_19460	COG0028	Belongs to the TPP enzyme family
D3Z87_19465	COG0583	DNA-binding transcription factor activity
D3Z87_19470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3Z87_19485	COG5337	Spore coat protein CotH
D3Z87_19495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3Z87_19505	COG0405	Gamma-glutamyltransferase
D3Z87_19510	COG1522	sequence-specific DNA binding
D3Z87_19515	COG2059	Chromate
D3Z87_19520	COG2059	Chromate
D3Z87_19530	COG0655	NAD(P)H dehydrogenase (quinone) activity
D3Z87_19535	COG0583	DNA-binding transcription factor activity
D3Z87_19540	COG1515	deoxyribonuclease V activity
D3Z87_19545	COG2849	repeat protein
D3Z87_19550	COG5444	nuclease activity
D3Z87_19570	COG3878	Protein conserved in bacteria
D3Z87_19575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3Z87_19580	COG4464	protein tyrosine phosphatase activity
D3Z87_19585	COG0489	protein tyrosine kinase activity
D3Z87_19590	COG3944	biosynthesis protein
D3Z87_19600	COG4715	Zinc finger, swim domain protein
D3Z87_19605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D3Z87_19615	COG0561	phosphatase activity
D3Z87_19620	COG1349	DNA-binding transcription factor activity
D3Z87_19625	COG0629	single-stranded DNA binding
D3Z87_19640	COG3764	Sortase (surface protein transpeptidase)
D3Z87_19645	COG0745	RESPONSE REGULATOR receiver
D3Z87_19645	COG2972	Histidine kinase
D3Z87_19650	COG1970	mechanosensitive ion channel activity
D3Z87_19655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D3Z87_19660	COG0457	Tetratricopeptide repeat
D3Z87_19665	COG4786	Flagellar basal body rod
D3Z87_19670	COG4786	Flagellar basal body rod
D3Z87_19675	COG1077	Cell shape determining protein MreB Mrl
D3Z87_19680	COG1609	Transcriptional regulator
D3Z87_19690	COG1846	Transcriptional regulator
D3Z87_19695	COG2814	Major facilitator Superfamily
D3Z87_19700	COG3420	alginic acid biosynthetic process
D3Z87_19705	COG1953	Uracil, thiamine, allantoin
D3Z87_19710	COG0477	Major facilitator Superfamily
D3Z87_19715	COG1335	isochorismatase
D3Z87_19725	COG0004	ammonium transporteR
D3Z87_19730	COG0347	Belongs to the P(II) protein family
D3Z87_19735	COG0671	phosphoesterase, PA-phosphatase related
D3Z87_19745	COG0739	heme binding
D3Z87_19750	COG1247	-acetyltransferase
D3Z87_19765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3Z87_19770	COG0789	Transcriptional regulator
D3Z87_19780	COG2910	NAD(P)H-binding
D3Z87_19785	COG1959	2 iron, 2 sulfur cluster binding
D3Z87_19790	COG0804	urea catabolic process
D3Z87_19795	COG0832	Belongs to the urease beta subunit family
D3Z87_19800	COG0831	urea catabolic process
D3Z87_19815	COG3237	CsbD-like
D3Z87_19820	COG1994	Peptidase M50
D3Z87_19825	COG0457	Tetratricopeptide repeat
D3Z87_19835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D3Z87_19840	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D3Z87_19850	COG2304	oxidoreductase activity
D3Z87_19860	COG2304	oxidoreductase activity
D3Z87_19865	COG2385	sporulation resulting in formation of a cellular spore
D3Z87_19870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D3Z87_19880	COG4836	Membrane
D3Z87_19890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D3Z87_19895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D3Z87_19900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D3Z87_19905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D3Z87_19910	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D3Z87_19915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D3Z87_19920	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D3Z87_19925	COG0356	it plays a direct role in the translocation of protons across the membrane
D3Z87_19935	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D3Z87_19940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D3Z87_19945	COG4475	Protein of unknown function (DUF436)
D3Z87_19950	COG0698	ribose 5-phosphate isomerase
D3Z87_19955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3Z87_19960	COG1971	Probably functions as a manganese efflux pump
D3Z87_19965	COG0009	L-threonylcarbamoyladenylate synthase
D3Z87_19970	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D3Z87_19990	COG2890	protein-(glutamine-N5) methyltransferase activity
D3Z87_19995	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D3Z87_20000	COG0346	lactoylglutathione lyase activity
D3Z87_20005	COG0789	Transcriptional regulator
D3Z87_20010	COG0679	Auxin Efflux Carrier
D3Z87_20015	COG0281	malic enzyme
D3Z87_20020	COG1435	thymidine kinase activity
D3Z87_20025	COG0254	rRNA binding
D3Z87_20030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D3Z87_20035	COG1494	fructose-1,6-bisphosphatase
D3Z87_20040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D3Z87_20045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D3Z87_20050	COG0191	fructose-bisphosphate aldolase activity
D3Z87_20055	COG2204	response regulator
D3Z87_20060	COG4821	SIS domain
D3Z87_20065	COG0504	CTP synthase activity
D3Z87_20070	COG3343	RNA polymerase activity
D3Z87_20075	COG1960	acyl-CoA dehydrogenase activity
D3Z87_20080	COG0247	lactate metabolic process
D3Z87_20080	COG2181	nitrate reductase activity
D3Z87_20085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3Z87_20090	COG4294	response to UV
D3Z87_20100	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3Z87_20105	COG1132	(ABC) transporter
D3Z87_20110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3Z87_20120	COG2181	nitrate reductase activity
D3Z87_20125	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D3Z87_20130	COG1140	nitrate reductase beta subunit
D3Z87_20135	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D3Z87_20140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3Z87_20150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3Z87_20155	COG2223	nitrite transmembrane transporter activity
D3Z87_20160	COG0018	arginyl-trna synthetase
D3Z87_20165	COG4506	Protein conserved in bacteria
D3Z87_20190	COG1131	(ABC) transporter
D3Z87_20195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D3Z87_20200	COG0612	Peptidase, M16
D3Z87_20205	COG0612	Peptidase, M16
D3Z87_20215	COG3391	amine dehydrogenase activity
D3Z87_20220	COG3391	amine dehydrogenase activity
D3Z87_20230	COG0457	Tetratricopeptide repeat
D3Z87_20240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D3Z87_20245	COG0010	Belongs to the arginase family
D3Z87_20250	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D3Z87_20255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3Z87_20270	COG1994	Peptidase M50
D3Z87_20275	COG1942	4-Oxalocrotonate Tautomerase
D3Z87_20280	COG1846	Transcriptional regulator
D3Z87_20285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D3Z87_20290	COG0477	Major facilitator Superfamily
D3Z87_20295	COG1959	2 iron, 2 sulfur cluster binding
D3Z87_20300	COG3465	dGTPase activity
D3Z87_20305	COG1078	dGTPase activity
D3Z87_20310	COG4844	belongs to the
D3Z87_20320	COG0697	spore germination
D3Z87_20325	COG0095	Lipoate-protein ligase
D3Z87_20330	COG0583	DNA-binding transcription factor activity
D3Z87_20335	COG0280	phosphate acetyltransferase
D3Z87_20345	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_20350	COG0436	Aminotransferase
D3Z87_20355	COG2814	Major facilitator Superfamily
D3Z87_20360	COG0151	Belongs to the GarS family
D3Z87_20365	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_20370	COG1917	Cupin 2, conserved barrel domain protein
D3Z87_20375	COG0077	Prephenate dehydratase
D3Z87_20380	COG2814	Major facilitator Superfamily
D3Z87_20385	COG0833	amino acid
D3Z87_20390	COG4187	Peptidase family M20/M25/M40
D3Z87_20395	COG1012	belongs to the aldehyde dehydrogenase family
D3Z87_20400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3Z87_20410	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D3Z87_20415	COG1091	dTDP-4-dehydrorhamnose reductase activity
D3Z87_20420	COG1088	dTDP-glucose 4,6-dehydratase activity
D3Z87_20425	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D3Z87_20430	COG3980	spore coat polysaccharide biosynthesis protein
D3Z87_20435	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D3Z87_20440	COG2089	acid synthase
D3Z87_20445	COG0456	acetyltransferase
D3Z87_20450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3Z87_20455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3Z87_20460	COG0463	Glycosyl transferase, family 2
D3Z87_20475	COG2363	Small membrane protein
D3Z87_20480	COG2233	PERMEase
D3Z87_20490	COG1012	belongs to the aldehyde dehydrogenase family
D3Z87_20495	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D3Z87_20500	COG1216	Glycosyl transferase, family 2
D3Z87_20515	COG1695	Transcriptional regulator
D3Z87_20520	COG0351	phosphomethylpyrimidine kinase
D3Z87_20530	COG1621	beta-fructofuranosidase activity
D3Z87_20535	COG1263	PTS System
D3Z87_20535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_20540	COG2116	formate transmembrane transporter activity
D3Z87_20545	COG3711	transcriptional antiterminator
D3Z87_20560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3Z87_20565	COG0778	Nitroreductase
D3Z87_20570	COG0772	Belongs to the SEDS family
D3Z87_20580	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D3Z87_20585	COG1845	cytochrome c oxidase, subunit III
D3Z87_20590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3Z87_20595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3Z87_20600	COG2261	transglycosylase associated protein
D3Z87_20605	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D3Z87_20610	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D3Z87_20615	COG2246	polysaccharide biosynthetic process
D3Z87_20620	COG1309	transcriptional regulator
D3Z87_20630	COG3162	membrane
D3Z87_20635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3Z87_20640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D3Z87_20645	COG2837	iron assimilation
D3Z87_20650	COG2822	iron ion transport
D3Z87_20655	COG0672	)-iron permease
D3Z87_20660	COG0352	thiamine-phosphate diphosphorylase activity
D3Z87_20665	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D3Z87_20670	COG0583	DNA-binding transcription factor activity
D3Z87_20675	COG1380	Effector of murein hydrolase LrgA
D3Z87_20680	COG1346	cytolysis
D3Z87_20685	COG2814	Major facilitator Superfamily
D3Z87_20690	COG4895	conserved protein (DUF2196)
D3Z87_20695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D3Z87_20700	COG0346	lactoylglutathione lyase activity
D3Z87_20720	COG1263	PTS System
D3Z87_20720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_20725	COG3711	transcriptional antiterminator
D3Z87_20730	COG1442	glycosyl transferase family 8
D3Z87_20735	COG5522	Integral membrane protein (intg_mem_TP0381)
D3Z87_20740	COG1846	Transcriptional regulator
D3Z87_20745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D3Z87_20750	COG2234	aminopeptidase activity
D3Z87_20755	COG2357	RelA SpoT domain protein
D3Z87_20760	COG1575	Belongs to the MenA family. Type 1 subfamily
D3Z87_20775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3Z87_20780	COG1696	Membrane protein involved in D-alanine export
D3Z87_20785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3Z87_20790	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D3Z87_20795	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D3Z87_20800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3Z87_20805	COG1486	melibiose metabolic process
D3Z87_20810	COG1447	Phosphotransferase system cellobiose-specific component IIA
D3Z87_20815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3Z87_20820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3Z87_20825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3Z87_20825	COG3711	transcriptional antiterminator
D3Z87_20835	COG2094	Belongs to the DNA glycosylase MPG family
D3Z87_20840	COG0753	catalase activity
D3Z87_20845	COG2814	Major facilitator Superfamily
D3Z87_20850	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D3Z87_20855	COG1131	(ABC) transporter
D3Z87_20875	COG1595	DNA-templated transcription, initiation
D3Z87_20880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D3Z87_20885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D3Z87_20890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D3Z87_20895	COG4988	ABC transporter
D3Z87_20900	COG1294	oxidase, subunit
D3Z87_20905	COG1271	oxidase subunit
D3Z87_20910	COG3493	citrate carrier protein
D3Z87_20915	COG0501	Belongs to the peptidase M48B family
D3Z87_20925	COG0726	polysaccharide deacetylase
D3Z87_20930	COG3842	ATPase activity
D3Z87_20935	COG2508	Transcriptional regulator
D3Z87_20940	COG1012	belongs to the aldehyde dehydrogenase family
D3Z87_20945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3Z87_20960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D3Z87_20965	COG1881	PFAM PEBP family protein
D3Z87_20970	COG0583	DNA-binding transcription factor activity
D3Z87_20980	COG4585	Histidine kinase
D3Z87_20985	COG2197	response regulator
D3Z87_20990	COG2195	Cleaves the N-terminal amino acid of tripeptides
D3Z87_21000	COG4894	glucomannan catabolic process
D3Z87_21005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D3Z87_21010	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D3Z87_21015	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_21020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D3Z87_21025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D3Z87_21030	COG2610	gluconate transmembrane transporter activity
D3Z87_21035	COG0500	methyltransferase
D3Z87_21040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3Z87_21055	COG0693	protein deglycase activity
D3Z87_21055	COG0753	catalase activity
D3Z87_21060	COG2851	Citrate transporter
D3Z87_21065	COG2273	Hydrolase Family 16
D3Z87_21070	COG3711	transcriptional antiterminator
D3Z87_21080	COG2270	Major facilitator Superfamily
D3Z87_21085	COG0513	Belongs to the DEAD box helicase family
D3Z87_21090	COG3401	FG-GAP repeat protein
D3Z87_21090	COG2755	lipolytic protein G-D-S-L family
D3Z87_21145	COG3209	COG3209 Rhs family protein
D3Z87_21150	COG0697	spore germination
D3Z87_21155	COG0589	response to stress
D3Z87_21160	COG2723	6-phospho-beta-galactosidase activity
D3Z87_21165	COG1263	PTS System
D3Z87_21165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_21165	COG2190	(PTS) system
D3Z87_21180	COG5444	nuclease activity
D3Z87_21195	COG3507	Belongs to the glycosyl hydrolase 43 family
D3Z87_21210	COG2986	histidine ammonia-lyase
D3Z87_21215	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D3Z87_21220	COG1228	amidohydrolase
D3Z87_21225	COG0010	Belongs to the arginase family
D3Z87_21230	COG0833	amino acid
D3Z87_21235	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D3Z87_21240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3Z87_21245	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D3Z87_21250	COG2390	Transcriptional regulator
D3Z87_21260	COG3192	ethanolamine utilization protein
D3Z87_21265	COG2079	MmgE PrpD family protein
D3Z87_21275	COG1126	abc transporter atp-binding protein
D3Z87_21280	COG0765	amino acid transport
D3Z87_21285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3Z87_21305	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D3Z87_21310	COG0561	phosphatase activity
D3Z87_21340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3Z87_21345	COG5294	Protein conserved in bacteria
D3Z87_21350	COG0577	efflux transmembrane transporter activity
D3Z87_21355	COG1136	(ABC) transporter
D3Z87_21360	COG2205	protein histidine kinase activity
D3Z87_21365	COG0745	RESPONSE REGULATOR receiver
D3Z87_21370	COG0191	fructose-bisphosphate aldolase activity
D3Z87_21375	COG1082	Xylose isomerase domain protein TIM barrel
D3Z87_21380	COG1082	Xylose isomerase domain protein TIM barrel
D3Z87_21385	COG0673	inositol 2-dehydrogenase activity
D3Z87_21390	COG2814	Major facilitator Superfamily
D3Z87_21395	COG1082	Xylose isomerase domain protein TIM barrel
D3Z87_21400	COG3962	Belongs to the TPP enzyme family
D3Z87_21405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3Z87_21410	COG3718	enzyme involved in inositol metabolism
D3Z87_21415	COG1012	belongs to the aldehyde dehydrogenase family
D3Z87_21420	COG1349	DNA-binding transcription factor activity
D3Z87_21425	COG0667	Aldo Keto reductase
D3Z87_21440	COG2814	Major facilitator Superfamily
D3Z87_21445	COG0326	Molecular chaperone. Has ATPase activity
D3Z87_21455	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_21460	COG1309	transcriptional regulator
D3Z87_21465	COG1012	belongs to the aldehyde dehydrogenase family
D3Z87_21470	COG0456	acetyltransferase
D3Z87_21475	COG2850	peptidyl-arginine hydroxylation
D3Z87_21480	COG2226	methyltransferase
D3Z87_21495	COG0367	asparagine synthase
D3Z87_21500	COG2814	Major facilitator Superfamily
D3Z87_21505	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3Z87_21515	COG1714	RDD family
D3Z87_21520	COG2311	Membrane
D3Z87_21525	COG1917	Cupin 2, conserved barrel domain protein
D3Z87_21530	COG1309	transcriptional regulator
D3Z87_21535	COG1028	Short-chain dehydrogenase reductase Sdr
D3Z87_21540	COG1846	Transcriptional regulator
D3Z87_21545	COG1380	Effector of murein hydrolase LrgA
D3Z87_21550	COG1346	cytolysis
D3Z87_21555	COG5039	Polysaccharide pyruvyl transferase
D3Z87_21560	COG1929	Belongs to the glycerate kinase type-1 family
D3Z87_21565	COG1802	Transcriptional regulator
D3Z87_21570	COG1070	Carbohydrate kinase
D3Z87_21575	COG2610	gluconate transmembrane transporter activity
D3Z87_21580	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D3Z87_21585	COG0450	alkyl hydroperoxide reductase
D3Z87_21590	COG3634	alkyl hydroperoxide reductase activity
D3Z87_21595	COG2723	6-phospho-beta-galactosidase activity
D3Z87_21600	COG2190	(PTS) system
D3Z87_21605	COG1263	PTS System
D3Z87_21605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3Z87_21605	COG2190	(PTS) system
D3Z87_21610	COG2188	Transcriptional regulator
D3Z87_21625	COG1131	(ABC) transporter
D3Z87_21630	COG1994	Peptidase M50
D3Z87_21635	COG0535	radical SAM domain protein
D3Z87_21645	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D3Z87_21650	COG5293	efflux transmembrane transporter activity
D3Z87_21660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3Z87_21665	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D3Z87_21680	COG1063	alcohol dehydrogenase
D3Z87_21700	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D3Z87_21705	COG0456	acetyltransferase
D3Z87_21710	COG0457	Tetratricopeptide repeat
D3Z87_21720	COG0010	Belongs to the arginase family
D3Z87_21725	COG0833	amino acid
D3Z87_21730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3Z87_21735	COG3829	transcription factor binding
D3Z87_21750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3Z87_21755	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D3Z87_21760	COG4853	Protein conserved in bacteria
D3Z87_21765	COG4863	YycH protein
D3Z87_21770	COG5002	protein histidine kinase activity
D3Z87_21775	COG0745	RESPONSE REGULATOR receiver
D3Z87_21805	COG0346	lactoylglutathione lyase activity
D3Z87_21810	COG0305	Participates in initiation and elongation during chromosome replication
D3Z87_21825	COG3093	addiction module antidote protein HigA
D3Z87_21830	COG2807	transmembrane transport
D3Z87_21835	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D3Z87_21840	COG0359	binds to the 23S rRNA
D3Z87_21845	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D3Z87_21850	COG4241	membrane
D3Z87_21860	COG5577	PFAM Coat F domain
D3Z87_21865	COG1733	regulation of RNA biosynthetic process
D3Z87_21870	COG1227	inorganic diphosphatase activity
D3Z87_21885	COG2271	Major facilitator Superfamily
D3Z87_21920	COG1131	(ABC) transporter
D3Z87_21935	COG4319	ketosteroid isomerase
D3Z87_21940	COG1357	PFAM Pentapeptide repeats (8 copies)
D3Z87_21945	COG2814	Major facilitator Superfamily
D3Z87_21950	COG0583	DNA-binding transcription factor activity
D3Z87_21955	COG2153	protein acetylation
D3Z87_21970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3Z87_21975	COG1846	Transcriptional regulator
D3Z87_21980	COG2153	protein acetylation
D3Z87_21985	COG2364	Membrane
D3Z87_21990	COG0456	acetyltransferase
D3Z87_21995	COG2315	Protein conserved in bacteria
D3Z87_22000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3Z87_22010	COG2814	Major facilitator Superfamily
D3Z87_22020	COG1331	Highly conserved protein containing a thioredoxin domain
D3Z87_22025	COG0789	Transcriptional regulator
D3Z87_22030	COG0697	spore germination
D3Z87_22035	COG1331	Highly conserved protein containing a thioredoxin domain
D3Z87_22040	COG1266	CAAX protease self-immunity
D3Z87_22045	COG0477	Major facilitator Superfamily
D3Z87_22045	COG2814	Major facilitator Superfamily
D3Z87_22050	COG0110	maltose O-acetyltransferase activity
D3Z87_22055	COG0346	lactoylglutathione lyase activity
D3Z87_22060	COG1609	Transcriptional regulator
D3Z87_22065	COG0708	Exodeoxyribonuclease III
D3Z87_22070	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D3Z87_22075	COG0629	single-stranded DNA binding
D3Z87_22080	COG0360	Binds together with S18 to 16S ribosomal RNA
D3Z87_22085	COG0012	GTP binding
D3Z87_22090	COG0243	molybdopterin cofactor binding
D3Z87_22095	COG4481	Protein conserved in bacteria
D3Z87_22100	COG3949	Membrane
D3Z87_22110	COG1475	DNA binding
D3Z87_22115	COG1192	Involved in chromosome partitioning
D3Z87_22125	COG1475	DNA binding
D3Z87_22130	COG0357	Ribosomal RNA small subunit methyltransferase G
D3Z87_22135	COG0445	tRNA wobble uridine modification
D3Z87_22140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D3Z87_22145	COG1847	R3H domain protein
D3Z87_22150	COG0706	membrane insertase activity
D3Z87_22155	COG0594	ribonuclease P activity
D3Z87_22160	COG0230	Belongs to the bacterial ribosomal protein bL34 family