locus-tag	class	description
J9312_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J9312_00010	COG0592	DNA-directed DNA polymerase activity
J9312_00015	COG2501	S4 domain
J9312_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J9312_00030	COG0187	DNA topoisomerase II activity
J9312_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J9312_00070	COG0516	GMP reductase activity
J9312_00070	COG0517	IMP dehydrogenase activity
J9312_00075	COG1686	Belongs to the peptidase S11 family
J9312_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
J9312_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
J9312_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J9312_00100	COG1428	Deoxynucleoside kinase
J9312_00105	COG1428	Deoxynucleoside kinase
J9312_00110	COG1388	LysM domain
J9312_00110	COG3858	chitin binding
J9312_00115	COG1335	isochorismatase
J9312_00120	COG0590	tRNA wobble adenosine to inosine editing
J9312_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J9312_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J9312_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J9312_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
J9312_00190	COG3853	Toxic anion resistance protein (TelA)
J9312_00195	COG1982	Orn Lys Arg decarboxylase major
J9312_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J9312_00205	COG3870	Protein conserved in bacteria
J9312_00210	COG1728	Protein conserved in bacteria
J9312_00215	COG0470	DNA polymerase III
J9312_00220	COG1774	PSP1 C-terminal conserved region
J9312_00225	COG4467	Involved in initiation control of chromosome replication
J9312_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J9312_00235	COG2827	Endonuclease containing a URI domain
J9312_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J9312_00245	COG3328	transposase activity
J9312_00250	COG2002	toxin-antitoxin pair type II binding
J9312_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9312_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9312_00260	COG0084	hydrolase, TatD family'
J9312_00265	COG3584	3D domain protein
J9312_00265	COG3583	domain protein
J9312_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J9312_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J9312_00285	COG4466	Protein conserved in bacteria
J9312_00295	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J9312_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J9312_00305	COG0251	oxidation-reduction process
J9312_00310	COG2088	sporulation resulting in formation of a cellular spore
J9312_00315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J9312_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J9312_00325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J9312_00330	COG0193	aminoacyl-tRNA hydrolase activity
J9312_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J9312_00345	COG2002	toxin-antitoxin pair type II binding
J9312_00350	COG2244	polysaccharide biosynthetic process
J9312_00355	COG3956	TIGRFAM MazG family protein
J9312_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J9312_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J9312_00380	COG1098	S1 RNA binding domain
J9312_00395	COG2208	phosphoserine phosphatase activity
J9312_00400	COG2304	oxidoreductase activity
J9312_00405	COG0515	serine threonine protein kinase
J9312_00410	COG0037	tRNA processing
J9312_00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J9312_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J9312_00425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J9312_00430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J9312_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J9312_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J9312_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J9312_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
J9312_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J9312_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J9312_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J9312_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J9312_00475	COG1396	sequence-specific DNA binding
J9312_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J9312_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J9312_00565	COG4463	regulation of RNA biosynthetic process
J9312_00570	COG3880	PFAM UvrB UvrC protein
J9312_00575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
J9312_00580	COG0542	response to heat
J9312_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J9312_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
J9312_00595	COG4956	integral membrane protein (PIN domain superfamily)
J9312_00600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J9312_00605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J9312_00610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J9312_00615	COG1045	serine acetyltransferase
J9312_00620	COG0215	cysteine-tRNA ligase activity
J9312_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
J9312_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J9312_00635	COG3688	RNA-binding protein containing a PIN domain
J9312_00640	COG1595	DNA-templated transcription, initiation
J9312_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J9312_00655	COG0250	Participates in transcription elongation, termination and antitermination
J9312_00665	COG0081	regulation of translation
J9312_00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J9312_00680	COG2813	Specifically methylates the guanine in position
J9312_00685	COG0085	RNA polymerase activity
J9312_00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J9312_00695	COG1358	cellular component organization or biogenesis
J9312_00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J9312_00705	COG0049	tRNA binding
J9312_00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J9312_00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J9312_00720	COG0596	Alpha beta hydrolase
J9312_00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J9312_00735	COG0088	Forms part of the polypeptide exit tunnel
J9312_00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J9312_00760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J9312_00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J9312_00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J9312_00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J9312_00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J9312_00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J9312_00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J9312_00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J9312_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J9312_00825	COG0200	Binds to the 23S rRNA
J9312_00830	COG0201	protein transport
J9312_00835	COG0563	adenylate kinase activity
J9312_00840	COG0024	Methionine aminopeptidase
J9312_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J9312_00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J9312_00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J9312_00870	COG0202	RNA polymerase activity
J9312_00875	COG0203	ribosomal protein L17
J9312_00880	COG1122	ATPase activity
J9312_00885	COG1122	ATPase activity
J9312_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J9312_00895	COG0101	tRNA pseudouridine synthase activity
J9312_00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J9312_00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J9312_00910	COG2226	methyltransferase
J9312_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_00925	COG0489	protein tyrosine kinase activity
J9312_00935	COG2194	sulfuric ester hydrolase activity
J9312_00940	COG0726	polysaccharide deacetylase
J9312_01025	COG0659	secondary active sulfate transmembrane transporter activity
J9312_01030	COG0385	Bile acid
J9312_01035	COG2819	hydrolase of the alpha beta superfamily
J9312_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_01055	COG2207	Transcriptional regulator
J9312_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_01060	COG3876	Protein conserved in bacteria
J9312_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
J9312_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J9312_01075	COG1263	PTS System
J9312_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_01080	COG1737	Transcriptional regulator
J9312_01085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J9312_01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_01095	COG1683	Conserved Protein
J9312_01125	COG1595	DNA-templated transcription, initiation
J9312_01130	COG5662	AntiSigma factor
J9312_01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J9312_01140	COG4856	YbbR-like protein
J9312_01145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J9312_01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J9312_01160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J9312_01165	COG2169	Transcriptional regulator
J9312_01170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J9312_01175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J9312_01180	COG3002	Belongs to the UPF0753 family
J9312_01185	COG0288	reversible hydration of carbon dioxide
J9312_01195	COG5609	conserved protein (DUF2294)
J9312_01200	COG0640	Transcriptional regulator
J9312_01205	COG2814	Major facilitator Superfamily
J9312_01220	COG0596	Alpha beta hydrolase
J9312_01225	COG0745	RESPONSE REGULATOR receiver
J9312_01230	COG0642	Histidine kinase
J9312_01240	COG0515	serine threonine protein kinase
J9312_01255	COG1113	amino acid transport
J9312_01275	COG2602	Beta-lactamase
J9312_01280	COG2124	cytochrome p450
J9312_01290	COG0531	amino acid
J9312_01295	COG0584	glycerophosphoryl diester phosphodiesterase
J9312_01300	COG2271	Major facilitator Superfamily
J9312_01310	COG0456	acetyltransferase
J9312_01310	COG1846	Transcriptional regulator
J9312_01325	COG3409	Peptidoglycan-binding domain 1 protein
J9312_01330	COG0697	spore germination
J9312_01335	COG1917	Cupin 2, conserved barrel domain protein
J9312_01335	COG2207	Transcriptional regulator
J9312_01360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J9312_01365	COG3591	Belongs to the peptidase S1B family
J9312_01375	COG0596	Alpha beta hydrolase
J9312_01380	COG1183	phosphatidylcholine synthase activity
J9312_01385	COG0586	Pfam SNARE associated Golgi protein
J9312_01390	COG0688	phosphatidylethanolamine metabolic process
J9312_01400	COG2312	Erythromycin esterase
J9312_01405	COG2207	Transcriptional regulator
J9312_01410	COG1054	Belongs to the UPF0176 family
J9312_01415	COG1301	dicarboxylic acid transport
J9312_01420	COG2190	(PTS) system
J9312_01420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_01420	COG1263	PTS System
J9312_01425	COG0363	glucosamine-6-phosphate deaminase activity
J9312_01430	COG2188	Transcriptional regulator
J9312_01440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J9312_01445	COG0833	amino acid
J9312_01450	COG2040	homocysteine
J9312_01460	COG2066	Belongs to the glutaminase family
J9312_01465	COG4191	Histidine kinase
J9312_01470	COG0784	Response regulator, receiver
J9312_01475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J9312_01480	COG1012	belongs to the aldehyde dehydrogenase family
J9312_01485	COG2271	Major facilitator Superfamily
J9312_01490	COG4948	Mandelate Racemase Muconate Lactonizing
J9312_01495	COG2186	Transcriptional regulator
J9312_01500	COG2721	sulfolactate sulfo-lyase activity
J9312_01505	COG3173	Aminoglycoside phosphotransferase
J9312_01515	COG0697	spore germination
J9312_01520	COG0745	RESPONSE REGULATOR receiver
J9312_01525	COG2205	protein histidine kinase activity
J9312_01530	COG1131	(ABC) transporter
J9312_01550	COG3773	Cell wall hydrolase
J9312_01555	COG2304	oxidoreductase activity
J9312_01565	COG3540	Alkaline phosphatase
J9312_01570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J9312_01575	COG0805	protein transport
J9312_01580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
J9312_01585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J9312_01590	COG0477	Major facilitator Superfamily
J9312_01595	COG1309	transcriptional regulator
J9312_01600	COG0252	asparaginase activity
J9312_01605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J9312_01610	COG1714	RDD family
J9312_01615	COG3012	SEC-C Motif Domain Protein
J9312_01615	COG1405	negative regulation of cell septum assembly
J9312_01625	COG3279	Response regulator of the LytR AlgR family
J9312_01635	COG1668	transmembrane transport
J9312_01640	COG0667	Aldo Keto reductase
J9312_01655	COG1595	DNA-templated transcription, initiation
J9312_01660	COG1595	DNA-templated transcription, initiation
J9312_01665	COG1876	peptidase activity
J9312_01675	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_01685	COG0803	Belongs to the bacterial solute-binding protein 9 family
J9312_01690	COG1121	(ABC) transporter
J9312_01695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J9312_01700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J9312_01705	COG2310	stress, protein
J9312_01710	COG2310	stress, protein
J9312_01715	COG2310	stress, protein
J9312_01720	COG0861	Integral membrane protein TerC family
J9312_01730	COG3853	Toxic anion resistance protein (TelA)
J9312_01735	COG0477	Major facilitator Superfamily
J9312_01740	COG2814	Major facilitator Superfamily
J9312_01745	COG0640	Transcriptional regulator
J9312_01750	COG4175	Glycine betaine
J9312_01750	COG0517	IMP dehydrogenase activity
J9312_01755	COG4176	ABC-type proline glycine betaine transport system permease component
J9312_01760	COG2113	Glycine betaine
J9312_01765	COG1473	amidohydrolase
J9312_01770	COG1288	antiporter activity
J9312_01785	COG0039	L-malate dehydrogenase activity
J9312_01800	COG3403	YqcI/YcgG family
J9312_01815	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J9312_01820	COG1660	Displays ATPase and GTPase activities
J9312_01825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J9312_01830	COG2226	methyltransferase
J9312_01835	COG0583	DNA-binding transcription factor activity
J9312_01840	COG3458	cephalosporin-C deacetylase activity
J9312_01845	COG3541	Predicted nucleotidyltransferase
J9312_01850	COG0506	proline dehydrogenase activity
J9312_01855	COG1012	belongs to the aldehyde dehydrogenase family
J9312_01860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J9312_01865	COG2508	Transcriptional regulator
J9312_01870	COG3689	TIGRFAM TIGR03943 family protein
J9312_01875	COG0701	Predicted permease
J9312_01880	COG2267	carboxylic ester hydrolase activity
J9312_01885	COG0492	ferredoxin-NADP+ reductase activity
J9312_01890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J9312_01890	COG1587	Uroporphyrinogen-III synthase
J9312_01895	COG2146	nitrite reductase [NAD(P)H] activity
J9312_01900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J9312_01905	COG0243	molybdopterin cofactor binding
J9312_01910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J9312_01915	COG2223	nitrite transmembrane transporter activity
J9312_01925	COG1376	ErfK ybiS ycfS ynhG family protein
J9312_01940	COG0765	amino acid transport
J9312_01945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J9312_01955	COG1714	RDD family
J9312_01965	COG1846	Transcriptional regulator
J9312_01980	COG2723	6-phospho-beta-galactosidase activity
J9312_01990	COG3209	COG3209 Rhs family protein
J9312_02000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J9312_02005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
J9312_02010	COG1733	regulation of RNA biosynthetic process
J9312_02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_02030	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J9312_02035	COG2814	Major facilitator Superfamily
J9312_02045	COG0697	spore germination
J9312_02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_02060	COG2364	Membrane
J9312_02065	COG1126	abc transporter atp-binding protein
J9312_02070	COG0765	amino acid transport
J9312_02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J9312_02080	COG0583	DNA-binding transcription factor activity
J9312_02085	COG0163	prenyltransferase activity
J9312_02090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J9312_02105	COG0596	Alpha beta hydrolase
J9312_02110	COG3104	oligopeptide transport
J9312_02115	COG5434	Belongs to the glycosyl hydrolase 28 family
J9312_02125	COG0697	spore germination
J9312_02135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J9312_02140	COG1136	(ABC) transporter
J9312_02145	COG0577	efflux transmembrane transporter activity
J9312_02150	COG0745	RESPONSE REGULATOR receiver
J9312_02155	COG5002	protein histidine kinase activity
J9312_02155	COG3850	Histidine kinase
J9312_02160	COG0457	Tetratricopeptide repeat
J9312_02180	COG0527	aspartate kinase activity
J9312_02185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_02190	COG4605	iron ion homeostasis
J9312_02195	COG4604	ABC transporter, ATP-binding protein
J9312_02200	COG4607	ABC-type enterochelin transport system periplasmic component
J9312_02210	COG2814	Major facilitator Superfamily
J9312_02215	COG1309	transcriptional regulator
J9312_02220	COG0778	Nitroreductase
J9312_02225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J9312_02230	COG0640	Transcriptional regulator
J9312_02235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_02240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J9312_02245	COG1012	belongs to the aldehyde dehydrogenase family
J9312_02250	COG4975	Glucose uptake
J9312_02255	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_02260	COG4549	nuclear export factor GLE1
J9312_02265	COG1276	copper resistance
J9312_02265	COG2372	response to copper ion
J9312_02270	COG1349	DNA-binding transcription factor activity
J9312_02280	COG2213	PTS system mannitol-specific
J9312_02285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_02290	COG0246	Mannitol dehydrogenase
J9312_02295	COG0473	3-isopropylmalate dehydrogenase activity
J9312_02300	COG0681	Belongs to the peptidase S26 family
J9312_02310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J9312_02320	COG0561	phosphatase activity
J9312_02325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J9312_02330	COG1914	H( )-stimulated, divalent metal cation uptake system
J9312_02335	COG4336	lyase activity
J9312_02340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J9312_02345	COG1984	allophanate hydrolase subunit 2
J9312_02350	COG1414	Transcriptional regulator
J9312_02355	COG2755	lipolytic protein G-D-S-L family
J9312_02365	COG2329	Antibiotic biosynthesis monooxygenase
J9312_02370	COG0768	penicillin binding
J9312_02375	COG4989	oxidoreductase activity
J9312_02380	COG3711	transcriptional antiterminator
J9312_02385	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_02390	COG2226	methyltransferase
J9312_02395	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_02400	COG1917	Cupin 2, conserved barrel domain protein
J9312_02405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_02410	COG3871	stress protein (general stress protein 26)
J9312_02420	COG2814	Major facilitator Superfamily
J9312_02425	COG1522	sequence-specific DNA binding
J9312_02430	COG0551	DNA topoisomerase type I activity
J9312_02430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J9312_02435	COG0494	nUDIX hydrolase
J9312_02440	COG0028	Belongs to the TPP enzyme family
J9312_02465	COG1914	H( )-stimulated, divalent metal cation uptake system
J9312_02470	COG2261	transglycosylase associated protein
J9312_02475	COG4876	unkown
J9312_02480	COG2217	Heavy metal translocating P-type atpase
J9312_02485	COG3729	General stress protein
J9312_02490	COG0662	Cupin 2, conserved barrel domain protein
J9312_02495	COG2329	Antibiotic biosynthesis monooxygenase
J9312_02500	COG3546	catalase activity
J9312_02505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J9312_02510	COG3290	protein histidine kinase activity
J9312_02515	COG4565	transcriptional regulatory protein
J9312_02520	COG1301	dicarboxylic acid transport
J9312_02525	COG0628	permease
J9312_02530	COG1131	(ABC) transporter
J9312_02535	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J9312_02545	COG1960	acyl-CoA dehydrogenase activity
J9312_02560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J9312_02565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_02570	COG1181	Belongs to the D-alanine--D-alanine ligase family
J9312_02575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J9312_02580	COG0513	Belongs to the DEAD box helicase family
J9312_02585	COG3402	PFAM membrane-flanked domain
J9312_02590	COG3428	Bacterial PH domain
J9312_02595	COG0705	Rhomboid family
J9312_02600	COG0736	holo-[acyl-carrier-protein] synthase activity
J9312_02605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J9312_02610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J9312_02615	COG0864	Transcriptional regulator
J9312_02620	COG2337	Toxic component of a toxin-antitoxin (TA) module
J9312_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_02630	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_02635	COG2172	sigma factor antagonist activity
J9312_02640	COG2208	phosphoserine phosphatase activity
J9312_02645	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_02650	COG2172	sigma factor antagonist activity
J9312_02655	COG1191	sigma factor activity
J9312_02660	COG2208	phosphoserine phosphatase activity
J9312_02675	COG1673	EVE domain
J9312_02680	COG1846	Transcriptional regulator
J9312_02685	COG2183	response to ionizing radiation
J9312_02695	COG3091	SprT-like family
J9312_02735	COG0582	viral genome integration into host DNA
J9312_02740	COG2856	Zn peptidase
J9312_02745	COG1396	sequence-specific DNA binding
J9312_02775	COG1674	ftsk spoiiie
J9312_02780	COG2946	Replication initiation factor
J9312_02815	COG0433	COG0433 Predicted ATPase
J9312_02825	COG5644	endopeptidase inhibitor activity
J9312_02830	COG0741	lytic transglycosylase activity
J9312_02830	COG0791	NLP P60 protein
J9312_02845	COG0457	Tetratricopeptide repeat
J9312_02860	COG1401	restriction endodeoxyribonuclease activity
J9312_02870	COG1802	Transcriptional regulator
J9312_02900	COG1476	TRANSCRIPTIONal
J9312_02920	COG0693	protein deglycase activity
J9312_02925	COG1278	Cold shock
J9312_02930	COG1329	Transcriptional regulator
J9312_02935	COG0697	spore germination
J9312_02940	COG1917	Cupin 2, conserved barrel domain protein
J9312_02940	COG2207	Transcriptional regulator
J9312_02945	COG0697	spore germination
J9312_02950	COG3708	Transcriptional regulator
J9312_02950	COG2207	Transcriptional regulator
J9312_02955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_02970	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
J9312_02985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_02990	COG1309	transcriptional regulator
J9312_02995	COG0697	spore germination
J9312_03000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_03005	COG2030	dehydratase
J9312_03010	COG3545	Serine hydrolase
J9312_03015	COG1733	regulation of RNA biosynthetic process
J9312_03020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_03025	COG0640	Transcriptional regulator
J9312_03030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J9312_03040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_03045	COG0697	spore germination
J9312_03050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_03055	COG0076	glutamate decarboxylase activity
J9312_03060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J9312_03065	COG0640	Transcriptional regulator
J9312_03070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J9312_03085	COG4585	Histidine kinase
J9312_03090	COG2197	response regulator
J9312_03095	COG2409	Drug exporters of the RND superfamily
J9312_03100	COG0596	Alpha beta hydrolase
J9312_03105	COG1811	Na channel or pump
J9312_03110	COG4978	Transcriptional regulator
J9312_03110	COG0789	Transcriptional regulator
J9312_03115	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J9312_03120	COG0778	Nitroreductase
J9312_03125	COG0346	lactoylglutathione lyase activity
J9312_03130	COG2259	Doxx family
J9312_03135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_03155	COG2323	membrane
J9312_03160	COG2323	membrane
J9312_03165	COG0071	Belongs to the small heat shock protein (HSP20) family
J9312_03180	COG1309	transcriptional regulator
J9312_03190	COG0456	acetyltransferase
J9312_03195	COG0488	(ABC) transporter
J9312_03200	COG1113	amino acid transport
J9312_03205	COG2318	DinB family
J9312_03210	COG1846	Transcriptional regulator
J9312_03215	COG2409	Drug exporters of the RND superfamily
J9312_03215	COG1033	growth of symbiont in host cell
J9312_03220	COG0778	Nitroreductase
J9312_03225	COG1846	Transcriptional regulator
J9312_03230	COG2814	Major facilitator Superfamily
J9312_03235	COG0730	response to heat
J9312_03240	COG1802	Transcriptional regulator
J9312_03245	COG3858	chitin binding
J9312_03245	COG1388	LysM domain
J9312_03250	COG1819	glycosyl
J9312_03260	COG1785	Belongs to the alkaline phosphatase family
J9312_03265	COG5646	InterPro IPR014922
J9312_03275	COG0454	-acetyltransferase
J9312_03280	COG1078	dGTPase activity
J9312_03285	COG1388	LysM domain
J9312_03290	COG2814	Major facilitator Superfamily
J9312_03295	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J9312_03310	COG2723	6-phospho-beta-galactosidase activity
J9312_03315	COG2188	Transcriptional regulator
J9312_03320	COG1940	carbohydrate kinase activity
J9312_03325	COG1482	cell wall glycoprotein biosynthetic process
J9312_03330	COG4124	Belongs to the glycosyl hydrolase 26 family
J9312_03375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J9312_03380	COG0802	atpase or kinase
J9312_03385	COG1214	PFAM Peptidase M22, glycoprotease
J9312_03390	COG0456	acetyltransferase
J9312_03395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J9312_03400	COG0488	(ABC) transporter
J9312_03405	COG0315	cyclic pyranopterin monophosphate synthase activity
J9312_03410	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
J9312_03415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J9312_03420	COG0805	protein transport
J9312_03430	COG1266	CAAX protease self-immunity
J9312_03440	COG0459	protein refolding
J9312_03455	COG0457	Tetratricopeptide repeat
J9312_03460	COG1063	alcohol dehydrogenase
J9312_03465	COG2211	Major facilitator Superfamily
J9312_03470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9312_03475	COG1842	Phage shock protein A
J9312_03480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J9312_03485	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J9312_03490	COG4260	virion core protein, lumpy skin disease virus
J9312_03500	COG2814	Major facilitator Superfamily
J9312_03505	COG1063	alcohol dehydrogenase
J9312_03510	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J9312_03515	COG0823	Involved in the tonB-independent uptake of proteins
J9312_03535	COG2267	carboxylic ester hydrolase activity
J9312_03545	COG2132	Multicopper oxidase
J9312_03550	COG1113	amino acid transport
J9312_03560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J9312_03565	COG0714	Associated with various cellular activities
J9312_03570	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
J9312_03575	COG1305	Transglutaminase-like
J9312_03585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J9312_03585	COG0519	Catalyzes the synthesis of GMP from XMP
J9312_03600	COG2252	PERMEase
J9312_03605	COG3064	Membrane
J9312_03615	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
J9312_03625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J9312_03630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J9312_03635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J9312_03640	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J9312_03645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J9312_03650	COG0047	phosphoribosylformylglycinamidine synthase activity
J9312_03655	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J9312_03660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J9312_03665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J9312_03670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J9312_03675	COG0138	bifunctional purine biosynthesis protein purh
J9312_03680	COG0151	Belongs to the GarS family
J9312_03685	COG1522	sequence-specific DNA binding
J9312_03690	COG0531	amino acid
J9312_03700	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J9312_03705	COG1470	cell adhesion involved in biofilm formation
J9312_03710	COG4496	protein, YerC YecD
J9312_03715	COG0069	glutamate synthase activity
J9312_03720	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
J9312_03725	COG0210	DNA helicase
J9312_03730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J9312_03735	COG4851	CamS sex pheromone cAM373 precursor
J9312_03745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9312_03750	COG1285	pathogenesis
J9312_03755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J9312_03760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J9312_03765	COG0154	amidase activity
J9312_03770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J9312_03775	COG1309	transcriptional regulator
J9312_03780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J9312_03785	COG1597	lipid kinase activity
J9312_03790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J9312_03820	COG5444	nuclease activity
J9312_03830	COG0457	Tetratricopeptide repeat
J9312_03840	COG0217	transcriptional regulatory protein
J9312_03850	COG1309	transcriptional regulator
J9312_03855	COG3631	Ketosteroid isomerase-related protein
J9312_03860	COG0702	epimerase
J9312_03875	COG3546	catalase activity
J9312_03880	COG0454	-acetyltransferase
J9312_03890	COG5578	integral membrane protein
J9312_03895	COG2972	Histidine kinase
J9312_03900	COG4753	response regulator
J9312_03900	COG2207	Transcriptional regulator
J9312_03905	COG1653	transport
J9312_03910	COG1175	transmembrane transport
J9312_03915	COG0395	ABC-type sugar transport system, permease component
J9312_03920	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
J9312_03925	COG2207	Transcriptional regulator
J9312_03930	COG2755	lipolytic protein G-D-S-L family
J9312_03940	COG5578	integral membrane protein
J9312_03945	COG3401	FG-GAP repeat protein
J9312_03950	COG3401	FG-GAP repeat protein
J9312_03955	COG2755	lipolytic protein G-D-S-L family
J9312_03960	COG1874	Beta-galactosidase
J9312_03970	COG1653	transport
J9312_03975	COG4209	transmembrane transport
J9312_03980	COG0395	ABC-type sugar transport system, permease component
J9312_03985	COG1486	melibiose metabolic process
J9312_03990	COG2323	membrane
J9312_03995	COG2329	Antibiotic biosynthesis monooxygenase
J9312_04000	COG0346	lactoylglutathione lyase activity
J9312_04015	COG5583	Uncharacterized small protein (DUF2292)
J9312_04020	COG0670	Belongs to the BI1 family
J9312_04025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J9312_04040	COG3328	transposase activity
J9312_04050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J9312_04050	COG2124	cytochrome p450
J9312_04055	COG1368	sulfuric ester hydrolase activity
J9312_04060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J9312_04065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J9312_04070	COG1442	glycosyl transferase family 8
J9312_04075	COG1216	Glycosyl transferase, family 2
J9312_04080	COG1442	glycosyl transferase family 8
J9312_04085	COG2223	nitrite transmembrane transporter activity
J9312_04090	COG1011	Hydrolase
J9312_04095	COG0531	amino acid
J9312_04100	COG1012	belongs to the aldehyde dehydrogenase family
J9312_04105	COG0840	transmembrane signaling receptor activity
J9312_04110	COG0488	(ABC) transporter
J9312_04120	COG0789	Transcriptional regulator
J9312_04125	COG2814	Major facilitator Superfamily
J9312_04135	COG0488	(ABC) transporter
J9312_04140	COG0513	Belongs to the DEAD box helicase family
J9312_04145	COG0456	acetyltransferase
J9312_04150	COG3328	transposase activity
J9312_04155	COG2130	NADP-dependent
J9312_04160	COG1120	ATPase activity
J9312_04165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_04170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_04175	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J9312_04190	COG3866	Pectate lyase
J9312_04195	COG0471	metal ion transport
J9312_04200	COG3290	protein histidine kinase activity
J9312_04205	COG4565	transcriptional regulatory protein
J9312_04210	COG3181	Tripartite tricarboxylate transporter family receptor
J9312_04215	COG2851	Citrate transporter
J9312_04220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_04225	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
J9312_04230	COG1254	Belongs to the acylphosphatase family
J9312_04235	COG2258	MOSC domain
J9312_04255	COG0024	Methionine aminopeptidase
J9312_04260	COG1263	PTS System
J9312_04260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_04265	COG1368	sulfuric ester hydrolase activity
J9312_04290	COG1263	PTS System
J9312_04290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_04295	COG0366	Alpha amylase catalytic
J9312_04300	COG2188	Transcriptional regulator
J9312_04305	COG0778	Nitroreductase
J9312_04310	COG0737	Belongs to the 5'-nucleotidase family
J9312_04315	COG0693	protein deglycase activity
J9312_04320	COG2814	Major facilitator Superfamily
J9312_04325	COG4840	Belongs to the UPF0435 family
J9312_04330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J9312_04335	COG4980	gas vesicle protein
J9312_04340	COG1295	ribonuclease BN
J9312_04345	COG0477	Major facilitator Superfamily
J9312_04350	COG0387	Pfam Sodium calcium exchanger
J9312_04360	COG0668	transmembrane transport
J9312_04365	COG0535	radical SAM domain protein
J9312_04375	COG0726	polysaccharide deacetylase
J9312_04380	COG2084	Dehydrogenase
J9312_04385	COG0598	Magnesium transport protein CorA
J9312_04390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J9312_04395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J9312_04405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J9312_04410	COG4637	Psort location Cytoplasmic, score
J9312_04420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J9312_04425	COG0022	dehydrogenase e1 component
J9312_04430	COG0508	dehydrogenase complex catalyzes the overall conversion of
J9312_04435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J9312_04440	COG3284	Transcriptional regulator
J9312_04450	COG1742	UPF0060 membrane protein
J9312_04475	COG4842	Belongs to the WXG100 family
J9312_04480	COG1486	melibiose metabolic process
J9312_04485	COG1737	Transcriptional regulator
J9312_04490	COG1263	PTS System
J9312_04490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_04495	COG5434	Belongs to the glycosyl hydrolase 28 family
J9312_04500	COG3328	transposase activity
J9312_04505	COG1132	(ABC) transporter
J9312_04510	COG1132	(ABC) transporter
J9312_04515	COG2259	Doxx family
J9312_04520	COG2514	catechol 2,3-dioxygenase activity
J9312_04525	COG1917	Cupin 2, conserved barrel domain protein
J9312_04525	COG4977	sequence-specific DNA binding
J9312_04530	COG2814	Major facilitator Superfamily
J9312_04535	COG1082	Xylose isomerase domain protein TIM barrel
J9312_04545	COG4585	Histidine kinase
J9312_04550	COG2197	response regulator
J9312_04555	COG1131	(ABC) transporter
J9312_04565	COG0842	Transport permease protein
J9312_04570	COG1695	Transcriptional regulator
J9312_04575	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J9312_04580	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
J9312_04585	COG1309	transcriptional regulator
J9312_04590	COG2814	Major facilitator Superfamily
J9312_04595	COG2318	DinB family
J9312_04600	COG2814	Major facilitator Superfamily
J9312_04605	COG1846	Transcriptional regulator
J9312_04610	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J9312_04610	COG0392	lysyltransferase activity
J9312_04615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_04620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_04625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_04630	COG0384	phenazine biosynthesis protein PhzF
J9312_04635	COG0778	Nitroreductase
J9312_04650	COG1090	epimerase
J9312_04655	COG2137	regulation of response to DNA damage stimulus
J9312_04665	COG2814	Major facilitator Superfamily
J9312_04685	COG3103	Sh3 type 3 domain protein
J9312_04690	COG5658	integral membrane protein
J9312_04695	COG0596	Alpha beta hydrolase
J9312_04700	COG0463	Glycosyl transferase, family 2
J9312_04705	COG4485	Bacterial membrane protein, YfhO
J9312_04710	COG1988	membrane-bound metal-dependent
J9312_04715	COG1194	a g-specific adenine glycosylase
J9312_04725	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_04740	COG3557	Belongs to the UPF0374 family
J9312_04745	COG1132	(ABC) transporter
J9312_04750	COG4129	membrane
J9312_04755	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J9312_04760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J9312_04765	COG0735	belongs to the Fur family
J9312_04875	COG4326	sporulation control protein
J9312_04885	COG5577	PFAM Coat F domain
J9312_04890	COG3340	Belongs to the peptidase S51 family
J9312_04895	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J9312_04910	COG0753	catalase activity
J9312_04915	COG1116	anion transmembrane transporter activity
J9312_04920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J9312_04925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J9312_04940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J9312_04950	COG1476	TRANSCRIPTIONal
J9312_04960	COG3382	B3 4 domain protein
J9312_04965	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J9312_04975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J9312_04980	COG0789	Transcriptional regulator
J9312_04985	COG1664	Polymer-forming cytoskeletal
J9312_04990	COG1664	Polymer-forming cytoskeletal
J9312_04995	COG2766	serine protein kinase
J9312_05000	COG2718	Belongs to the UPF0229 family
J9312_05005	COG1846	Transcriptional regulator
J9312_05010	COG1566	PFAM secretion protein HlyD family protein
J9312_05015	COG2814	Major facilitator Superfamily
J9312_05020	COG0655	NAD(P)H dehydrogenase (quinone) activity
J9312_05040	COG1725	Transcriptional regulator
J9312_05045	COG1131	(ABC) transporter
J9312_05050	COG1131	(ABC) transporter
J9312_05055	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J9312_05060	COG1278	Cold shock
J9312_05065	COG1464	Belongs to the NlpA lipoprotein family
J9312_05070	COG3706	GGDEF domain
J9312_05075	COG1823	symporter activity
J9312_05080	COG5444	nuclease activity
J9312_05105	COG0582	viral genome integration into host DNA
J9312_05110	COG2946	Replication initiation factor
J9312_05165	COG5644	endopeptidase inhibitor activity
J9312_05170	COG0741	lytic transglycosylase activity
J9312_05170	COG0791	NLP P60 protein
J9312_05190	COG0457	Tetratricopeptide repeat
J9312_05215	COG4085	toxin activity
J9312_05215	COG1525	nuclease
J9312_05215	COG0737	Belongs to the 5'-nucleotidase family
J9312_05220	COG3764	Sortase (surface protein transpeptidase)
J9312_05225	COG0564	pseudouridine synthase activity
J9312_05235	COG0517	IMP dehydrogenase activity
J9312_05240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J9312_05245	COG3153	acetyltransferase
J9312_05245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J9312_05250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J9312_05255	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
J9312_05260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J9312_05265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J9312_05270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J9312_05275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J9312_05280	COG4585	Histidine kinase
J9312_05280	COG2203	Gaf domain
J9312_05285	COG2197	response regulator
J9312_05290	COG0431	NADPH-dependent FMN reductase
J9312_05305	COG1388	LysM domain
J9312_05305	COG0791	NLP P60 protein
J9312_05310	COG1959	2 iron, 2 sulfur cluster binding
J9312_05315	COG0668	transmembrane transport
J9312_05320	COG2719	SpoVR family
J9312_05325	COG1785	Belongs to the alkaline phosphatase family
J9312_05330	COG1388	LysM domain
J9312_05330	COG0791	NLP P60 protein
J9312_05335	COG0583	DNA-binding transcription factor activity
J9312_05340	COG0372	Belongs to the citrate synthase family
J9312_05345	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_05350	COG0531	amino acid
J9312_05355	COG0733	neurotransmitter:sodium symporter activity
J9312_05360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_05365	COG0456	acetyltransferase
J9312_05380	COG1595	DNA-templated transcription, initiation
J9312_05385	COG0667	Aldo Keto reductase
J9312_05390	COG0204	Acyl-transferase
J9312_05395	COG1253	flavin adenine dinucleotide binding
J9312_05400	COG0789	Transcriptional regulator
J9312_05410	COG1253	flavin adenine dinucleotide binding
J9312_05415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J9312_05420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J9312_05425	COG0584	glycerophosphoryl diester phosphodiesterase
J9312_05435	COG0668	transmembrane transport
J9312_05440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J9312_05445	COG0726	polysaccharide deacetylase
J9312_05450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J9312_05455	COG1757	Na H antiporter
J9312_05460	COG0589	response to stress
J9312_05470	COG1132	(ABC) transporter
J9312_05475	COG1132	(ABC) transporter
J9312_05480	COG0702	epimerase
J9312_05500	COG0189	ligase activity
J9312_05505	COG0189	ligase activity
J9312_05510	COG4399	Belongs to the UPF0754 family
J9312_05515	COG3679	Belongs to the UPF0342 family
J9312_05520	COG4335	DNA alkylation repair
J9312_05525	COG0561	phosphatase activity
J9312_05530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J9312_05535	COG0475	glutathione-regulated potassium exporter activity
J9312_05540	COG0490	domain, Protein
J9312_05550	COG1024	Enoyl-CoA hydratase
J9312_05560	COG4152	abc transporter atp-binding protein
J9312_05565	COG1668	transmembrane transport
J9312_05570	COG0420	3'-5' exonuclease activity
J9312_05575	COG4717	serine-type aminopeptidase activity
J9312_05580	COG3481	metal-dependent phosphohydrolase, HD sub domain
J9312_05590	COG3328	transposase activity
J9312_05595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J9312_05625	COG1846	Transcriptional regulator
J9312_05630	COG4980	gas vesicle protein
J9312_05645	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J9312_05650	COG0537	adenosine 5'-monophosphoramidase activity
J9312_05655	COG1131	(ABC) transporter
J9312_05660	COG4473	ABC transporter
J9312_05670	COG1473	amidohydrolase
J9312_05675	COG3069	C4-dicarboxylate transmembrane transporter activity
J9312_05685	COG2329	Antibiotic biosynthesis monooxygenase
J9312_05690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J9312_05695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J9312_05700	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J9312_05705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
J9312_05710	COG1309	transcriptional regulator
J9312_05715	COG1511	domain protein
J9312_05720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J9312_05725	COG4377	Putative membrane peptidase family (DUF2324)
J9312_05735	COG1363	Peptidase, m42
J9312_05740	COG4405	Protein conserved in bacteria
J9312_05745	COG1301	dicarboxylic acid transport
J9312_05755	COG1234	tRNA 3'-trailer cleavage
J9312_05760	COG0095	Lipoate-protein ligase
J9312_05765	COG0702	epimerase
J9312_05770	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_05780	COG0501	Belongs to the peptidase M48B family
J9312_05785	COG1404	Belongs to the peptidase S8 family
J9312_05790	COG0456	acetyltransferase
J9312_05795	COG0604	alcohol dehydrogenase
J9312_05800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J9312_05805	COG0406	alpha-ribazole phosphatase activity
J9312_05810	COG0183	Belongs to the thiolase family
J9312_05815	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_05820	COG1268	BioY protein
J9312_05825	COG0840	transmembrane signaling receptor activity
J9312_05835	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_05845	COG4903	ComK protein
J9312_05850	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_05860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J9312_05875	COG0398	Pfam SNARE associated Golgi protein
J9312_05880	COG0681	Belongs to the peptidase S26 family
J9312_05885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J9312_05890	COG1846	Transcriptional regulator
J9312_05900	COG0738	Major facilitator superfamily
J9312_05935	COG0561	phosphatase activity
J9312_05940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J9312_05945	COG1609	Transcriptional regulator
J9312_05950	COG3180	Ammonia monooxygenase
J9312_05955	COG2814	Major facilitator Superfamily
J9312_05955	COG0477	Major facilitator Superfamily
J9312_05960	COG4533	DNA binding
J9312_05970	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
J9312_05975	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
J9312_05980	COG1074	ATP-dependent DNA helicase activity
J9312_05985	COG0420	3'-5' exonuclease activity
J9312_05990	COG0419	ATPase involved in DNA repair
J9312_05995	COG1403	HNH endonuclease
J9312_06035	COG5337	Spore coat protein CotH
J9312_06040	COG0179	Fumarylacetoacetate (FAA) hydrolase
J9312_06050	COG1404	Belongs to the peptidase S8 family
J9312_06060	COG0367	asparagine synthase
J9312_06065	COG1562	ergosterol biosynthetic process
J9312_06070	COG0534	Mate efflux family protein
J9312_06075	COG1917	Cupin 2, conserved barrel domain protein
J9312_06075	COG2207	Transcriptional regulator
J9312_06080	COG1609	Transcriptional regulator
J9312_06085	COG0673	inositol 2-dehydrogenase activity
J9312_06090	COG2318	DinB family
J9312_06095	COG1279	arginine transmembrane transporter activity
J9312_06100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_06105	COG1357	PFAM Pentapeptide repeats (8 copies)
J9312_06110	COG2267	carboxylic ester hydrolase activity
J9312_06115	COG0529	Catalyzes the synthesis of activated sulfate
J9312_06125	COG0175	sulfate reduction
J9312_06130	COG2045	Belongs to the ComB family
J9312_06135	COG1809	phosphosulfolactate synthase activity
J9312_06140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_06145	COG4948	Mandelate Racemase Muconate Lactonizing
J9312_06150	COG2814	Major facilitator Superfamily
J9312_06155	COG0454	-acetyltransferase
J9312_06160	COG2153	protein acetylation
J9312_06165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J9312_06165	COG0646	methionine synthase
J9312_06170	COG1666	GTP binding
J9312_06175	COG2996	Protein conserved in bacteria
J9312_06195	COG1695	Transcriptional regulator
J9312_06210	COG3227	Zinc metalloprotease (Elastase)
J9312_06215	COG1307	EDD domain protein, DegV family
J9312_06220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_06240	COG0561	phosphatase activity
J9312_06245	COG1073	alpha beta
J9312_06250	COG2151	metal-sulfur cluster biosynthetic enzyme
J9312_06260	COG0277	FAD linked oxidase domain protein
J9312_06270	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J9312_06275	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J9312_06285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J9312_06290	COG0505	Belongs to the CarA family
J9312_06295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J9312_06300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J9312_06320	COG2267	carboxylic ester hydrolase activity
J9312_06330	COG1744	ABC transporter substrate-binding protein PnrA-like
J9312_06345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J9312_06350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J9312_06355	COG5504	Zn-dependent protease
J9312_06360	COG0444	Belongs to the ABC transporter superfamily
J9312_06365	COG4608	Belongs to the ABC transporter superfamily
J9312_06375	COG0601	transmembrane transport
J9312_06380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J9312_06390	COG0180	Tryptophanyl-tRNA synthetase
J9312_06395	COG4166	transmembrane transport
J9312_06400	COG0601	transmembrane transport
J9312_06405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J9312_06410	COG0444	Belongs to the ABC transporter superfamily
J9312_06415	COG4608	Belongs to the ABC transporter superfamily
J9312_06420	COG2814	Major facilitator Superfamily
J9312_06425	COG0456	acetyltransferase
J9312_06430	COG1393	Belongs to the ArsC family
J9312_06435	COG0861	Integral membrane protein TerC family
J9312_06445	COG4862	establishment of competence for transformation
J9312_06455	COG4469	Competence protein
J9312_06460	COG1164	Oligoendopeptidase f
J9312_06470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J9312_06475	COG2346	COG2346, Truncated hemoglobins
J9312_06480	COG0741	lytic transglycosylase activity
J9312_06485	COG4116	CYTH
J9312_06495	COG2357	RelA SpoT domain protein
J9312_06500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J9312_06505	COG0564	pseudouridine synthase activity
J9312_06510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J9312_06515	COG0569	domain protein
J9312_06515	COG0475	glutathione-regulated potassium exporter activity
J9312_06520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J9312_06525	COG0352	thiamine-phosphate diphosphorylase activity
J9312_06530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J9312_06535	COG2104	thiamine diphosphate biosynthetic process
J9312_06540	COG2022	thiamine diphosphate biosynthetic process
J9312_06545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J9312_06550	COG0351	phosphomethylpyrimidine kinase
J9312_06555	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J9312_06610	COG0210	DNA helicase
J9312_06625	COG2153	protein acetylation
J9312_06630	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J9312_06635	COG2382	esterase
J9312_06640	COG0626	cystathionine gamma-synthase activity
J9312_06645	COG0626	cystathionine gamma-synthase activity
J9312_06650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_06655	COG5505	Protein of unknown function (DUF819)
J9312_06685	COG1396	sequence-specific DNA binding
J9312_06765	COG0457	Tetratricopeptide repeat
J9312_06770	COG5444	nuclease activity
J9312_06780	COG3328	transposase activity
J9312_06785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_06795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J9312_06810	COG0109	protoheme IX farnesyltransferase activity
J9312_06820	COG0726	polysaccharide deacetylase
J9312_06835	COG5504	Zn-dependent protease
J9312_06840	COG2205	protein histidine kinase activity
J9312_06850	COG3383	formate dehydrogenase (NAD+) activity
J9312_06855	COG2427	Protein of unknown function (DUF1641)
J9312_06865	COG1051	belongs to the nudix hydrolase family
J9312_06875	COG2124	cytochrome p450
J9312_06880	COG1819	glycosyl
J9312_06890	COG1587	Uroporphyrinogen-III synthase
J9312_06895	COG0390	transport system, permease component
J9312_06900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J9312_06905	COG0697	spore germination
J9312_06910	COG4297	protein containing double-stranded beta helix domain
J9312_06920	COG1252	NADH dehydrogenase
J9312_06925	COG1904	glucuronate isomerase
J9312_06930	COG2211	Major facilitator Superfamily
J9312_06935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J9312_06940	COG1063	alcohol dehydrogenase
J9312_06945	COG1312	Catalyzes the dehydration of D-mannonate
J9312_06950	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_06955	COG2271	Major facilitator Superfamily
J9312_06960	COG1609	Transcriptional regulator
J9312_06965	COG0246	Mannitol dehydrogenase
J9312_06970	COG2721	sulfolactate sulfo-lyase activity
J9312_06975	COG0730	response to heat
J9312_06980	COG2318	DinB family
J9312_06985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J9312_06990	COG0457	Tetratricopeptide repeat
J9312_07005	COG1388	LysM domain
J9312_07005	COG5632	N-Acetylmuramoyl-L-alanine amidase
J9312_07005	COG3409	Peptidoglycan-binding domain 1 protein
J9312_07015	COG4195	phage-related replication protein
J9312_07020	COG3546	catalase activity
J9312_07025	COG2856	Zn peptidase
J9312_07030	COG1396	sequence-specific DNA binding
J9312_07040	COG1522	sequence-specific DNA binding
J9312_07045	COG1484	DNA-dependent DNA replication
J9312_07065	COG1595	DNA-templated transcription, initiation
J9312_07070	COG3728	DNA packaging
J9312_07070	COG5484	DNA packaging
J9312_07075	COG1783	phage Terminase large subunit
J9312_07080	COG5518	Phage portal protein
J9312_07085	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J9312_07090	COG4653	Phage capsid family
J9312_07140	COG5412	phage tail tape measure protein
J9312_07140	COG3953	SLT domain
J9312_07140	COG5412	phage tail tape measure protein
J9312_07140	COG3953	SLT domain
J9312_07140	COG3953	SLT domain
J9312_07140	COG5412	phage tail tape measure protein
J9312_07150	COG4193	domain, Protein
J9312_07160	COG3628	GPW Gp25 family protein
J9312_07165	COG3299	homolog of phage Mu protein gp47
J9312_07170	COG3778	Protein conserved in bacteria
J9312_07210	COG5632	N-Acetylmuramoyl-L-alanine amidase
J9312_07210	COG3409	Peptidoglycan-binding domain 1 protein
J9312_07230	COG0306	phosphate transporter
J9312_07235	COG1392	Phosphate transport regulator
J9312_07245	COG0346	lactoylglutathione lyase activity
J9312_07250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J9312_07255	COG0463	Glycosyl transferase, family 2
J9312_07265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9312_07270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J9312_07275	COG2362	D-Aminopeptidase
J9312_07280	COG0601	transmembrane transport
J9312_07285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J9312_07290	COG0444	Belongs to the ABC transporter superfamily
J9312_07295	COG4166	transmembrane transport
J9312_07300	COG1619	proteins homologs of microcin C7 resistance protein MccF
J9312_07305	COG4948	Mandelate Racemase Muconate Lactonizing
J9312_07310	COG0791	NLP P60 protein
J9312_07315	COG4608	Belongs to the ABC transporter superfamily
J9312_07320	COG2706	6-phosphogluconolactonase activity
J9312_07330	COG1607	acyl-coa hydrolase
J9312_07335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J9312_07335	COG1017	nitric oxide dioxygenase activity
J9312_07345	COG2323	membrane
J9312_07350	COG2318	DinB family
J9312_07355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_07360	COG2076	Multidrug Resistance protein
J9312_07365	COG2076	Multidrug Resistance protein
J9312_07370	COG0788	formyltetrahydrofolate deformylase activity
J9312_07375	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J9312_07380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J9312_07385	COG1764	response to oxidative stress
J9312_07390	COG1846	Transcriptional regulator
J9312_07395	COG1764	response to oxidative stress
J9312_07405	COG0590	tRNA wobble adenosine to inosine editing
J9312_07410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J9312_07415	COG1404	Belongs to the peptidase S8 family
J9312_07420	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_07425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J9312_07430	COG1122	ATPase activity
J9312_07435	COG4721	ABC-type cobalt transport system, permease component
J9312_07445	COG0745	RESPONSE REGULATOR receiver
J9312_07450	COG5002	protein histidine kinase activity
J9312_07450	COG3850	Histidine kinase
J9312_07455	COG3212	peptidase
J9312_07460	COG3212	peptidase
J9312_07470	COG2239	Acts as a magnesium transporter
J9312_07475	COG0789	Transcriptional regulator
J9312_07490	COG1846	Transcriptional regulator
J9312_07495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J9312_07500	COG0726	polysaccharide deacetylase
J9312_07505	COG1408	metallophosphoesterase
J9312_07515	COG0463	Glycosyl transferase, family 2
J9312_07520	COG1793	dna ligase
J9312_07520	COG3285	dna ligase
J9312_07525	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
J9312_07530	COG3300	MHYT domain
J9312_07530	COG5001	Diguanylate cyclase
J9312_07535	COG0586	Pfam SNARE associated Golgi protein
J9312_07540	COG0861	Integral membrane protein TerC family
J9312_07545	COG1191	sigma factor activity
J9312_07565	COG0501	Belongs to the peptidase M48B family
J9312_07570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J9312_07585	COG3594	Acyltransferase
J9312_07590	COG5002	protein histidine kinase activity
J9312_07595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J9312_07605	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
J9312_07610	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
J9312_07615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J9312_07620	COG0436	Aminotransferase
J9312_07625	COG1850	ribulose-bisphosphate carboxylase activity
J9312_07630	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
J9312_07635	COG0235	Class ii aldolase
J9312_07640	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
J9312_07645	COG3339	Conserved Protein
J9312_07660	COG3852	Histidine kinase
J9312_07665	COG1846	Transcriptional regulator
J9312_07670	COG1360	Flagellar Motor Protein
J9312_07675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J9312_07680	COG0542	response to heat
J9312_07685	COG3949	Membrane
J9312_07690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J9312_07695	COG0720	synthase
J9312_07700	COG0602	queuosine metabolic process
J9312_07705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J9312_07710	COG1733	regulation of RNA biosynthetic process
J9312_07715	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_07785	COG4873	Protein conserved in bacteria
J9312_07795	COG3773	Cell wall hydrolase
J9312_07800	COG2244	polysaccharide biosynthetic process
J9312_07805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_07810	COG2217	Heavy metal translocating P-type atpase
J9312_07820	COG0006	proline dipeptidase activity
J9312_07825	COG1609	Transcriptional regulator
J9312_07830	COG3711	transcriptional antiterminator
J9312_07835	COG1263	PTS System
J9312_07835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_07835	COG2190	(PTS) system
J9312_07840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_07845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J9312_07855	COG1533	DNA photolyase activity
J9312_07860	COG0456	acetyltransferase
J9312_07865	COG0840	transmembrane signaling receptor activity
J9312_07870	COG2084	Dehydrogenase
J9312_07875	COG3328	transposase activity
J9312_07880	COG2340	Cysteine-rich secretory protein family
J9312_07885	COG0768	penicillin binding
J9312_07890	COG4191	Histidine kinase
J9312_07895	COG0436	Aminotransferase
J9312_07905	COG0784	Response regulator, receiver
J9312_07905	COG0835	chemotaxis
J9312_07915	COG2814	Major facilitator Superfamily
J9312_07920	COG1376	ErfK ybiS ycfS ynhG family protein
J9312_07925	COG1408	metallophosphoesterase
J9312_07930	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_07935	COG2200	EAL domain
J9312_07940	COG4703	Protein of unknown function (DUF1797)
J9312_07945	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
J9312_07955	COG0517	IMP dehydrogenase activity
J9312_07960	COG0583	DNA-binding transcription factor activity
J9312_07965	COG0716	FMN binding
J9312_07975	COG0716	FMN binding
J9312_07980	COG2171	N-acyltransferase activity
J9312_07985	COG1473	amidohydrolase
J9312_07995	COG0668	transmembrane transport
J9312_08000	COG0450	alkyl hydroperoxide reductase
J9312_08005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_08020	COG0746	molybdenum cofactor guanylyltransferase activity
J9312_08025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J9312_08030	COG0303	'Molybdopterin
J9312_08035	COG1763	Mo-molybdopterin cofactor biosynthetic process
J9312_08040	COG0314	molybdopterin synthase activity
J9312_08045	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J9312_08050	COG1132	(ABC) transporter
J9312_08055	COG1132	(ABC) transporter
J9312_08065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J9312_08070	COG1136	(ABC) transporter
J9312_08075	COG0577	efflux transmembrane transporter activity
J9312_08080	COG1349	DNA-binding transcription factor activity
J9312_08085	COG1105	Belongs to the carbohydrate kinase PfkB family
J9312_08090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J9312_08090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J9312_08090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_08095	COG0681	Belongs to the peptidase S26 family
J9312_08105	COG0488	(ABC) transporter
J9312_08110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J9312_08115	COG2309	aminopeptidase activity
J9312_08125	COG1077	Cell shape determining protein MreB Mrl
J9312_08130	COG2002	toxin-antitoxin pair type II binding
J9312_08135	COG3852	Histidine kinase
J9312_08140	COG2105	PFAM AIG2 family protein
J9312_08140	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
J9312_08145	COG0569	domain protein
J9312_08150	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J9312_08155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J9312_08160	COG5503	Protein of unknown function (DUF1447)
J9312_08165	COG0561	phosphatase activity
J9312_08170	COG0242	peptide deformylase activity
J9312_08185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J9312_08190	COG0022	dehydrogenase e1 component
J9312_08195	COG0508	dehydrogenase complex catalyzes the overall conversion of
J9312_08200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J9312_08205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_08215	COG1982	Orn Lys Arg decarboxylase major
J9312_08220	COG4476	Belongs to the UPF0223 family
J9312_08225	COG4493	Belongs to the UPF0637 family
J9312_08235	COG0483	inositol monophosphate 1-phosphatase activity
J9312_08245	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J9312_08265	COG1595	DNA-templated transcription, initiation
J9312_08285	COG1217	gtp-binding protein TYPA
J9312_08295	COG4896	Protein conserved in bacteria
J9312_08305	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J9312_08310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J9312_08315	COG2066	Belongs to the glutaminase family
J9312_08320	COG4838	Belongs to the UPF0358 family
J9312_08325	COG0772	Belongs to the SEDS family
J9312_08330	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J9312_08335	COG1612	heme a metabolic process
J9312_08340	COG0109	protoheme IX farnesyltransferase activity
J9312_08345	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J9312_08345	COG2010	Cytochrome c
J9312_08350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J9312_08355	COG1845	cytochrome c oxidase, subunit III
J9312_08360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J9312_08365	COG3336	cytochrome c oxidase
J9312_08375	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
J9312_08380	COG2340	Cysteine-rich secretory protein family
J9312_08395	COG3679	Belongs to the UPF0342 family
J9312_08400	COG4471	UPF0298 protein
J9312_08405	COG0742	ribosomal rna small subunit methyltransferase
J9312_08410	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J9312_08415	COG3314	Sporulation integral membrane protein YlbJ
J9312_08420	COG1752	Esterase of the alpha-beta hydrolase superfamily
J9312_08425	COG3480	Lon protease (S16) C-terminal proteolytic domain
J9312_08430	COG1323	Belongs to the UPF0348 family
J9312_08440	COG1399	metal-binding, possibly nucleic acid-binding protein
J9312_08455	COG0454	-acetyltransferase
J9312_08460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J9312_08465	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
J9312_08470	COG2001	Belongs to the MraZ family
J9312_08475	COG0275	rRNA processing
J9312_08480	COG4839	cell division protein FtsL
J9312_08485	COG0768	penicillin binding
J9312_08490	COG0768	penicillin binding
J9312_08495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J9312_08500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J9312_08505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J9312_08510	COG0772	Belongs to the SEDS family
J9312_08515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J9312_08520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J9312_08525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J9312_08530	COG3879	Bacterial protein of unknown function (DUF881)
J9312_08535	COG3879	Bacterial protein of unknown function (DUF881)
J9312_08540	COG3856	small basic protein
J9312_08545	COG0849	cell division
J9312_08550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J9312_08555	COG4412	M6 family metalloprotease domain protein
J9312_08555	COG1404	Belongs to the peptidase S8 family
J9312_08565	COG1191	sigma factor activity
J9312_08570	COG1191	sigma factor activity
J9312_08575	COG1119	ATPase activity
J9312_08580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J9312_08585	COG1873	PFAM PRC-barrel domain
J9312_08590	COG1496	oxidoreductase activity
J9312_08595	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J9312_08600	COG1799	cell septum assembly
J9312_08605	COG0762	integral membrane protein
J9312_08610	COG2302	S4 RNA-binding domain
J9312_08615	COG3599	regulation of cell shape
J9312_08620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J9312_08625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J9312_08630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J9312_08635	COG0564	pseudouridine synthase activity
J9312_08640	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J9312_08645	COG2233	PERMEase
J9312_08650	COG0540	Belongs to the ATCase OTCase family
J9312_08655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J9312_08660	COG0505	Belongs to the CarA family
J9312_08665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J9312_08670	COG0543	2 iron, 2 sulfur cluster binding
J9312_08675	COG0167	dihydroorotate dehydrogenase activity
J9312_08680	COG0284	orotidine-5'-phosphate decarboxylase activity
J9312_08685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J9312_08690	COG0175	sulfate reduction
J9312_08695	COG0306	phosphate transporter
J9312_08700	COG2046	Belongs to the sulfate adenylyltransferase family
J9312_08705	COG0529	Catalyzes the synthesis of activated sulfate
J9312_08710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J9312_08715	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
J9312_08720	COG1648	precorrin-2 dehydrogenase activity
J9312_08725	COG1293	RNA-binding protein homologous to eukaryotic snRNP
J9312_08730	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J9312_08735	COG1561	YicC-like family, N-terminal region
J9312_08745	COG0194	GDP metabolic process
J9312_08750	COG1758	RNA polymerase activity
J9312_08755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J9312_08760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J9312_08765	COG0242	peptide deformylase activity
J9312_08770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J9312_08775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J9312_08775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J9312_08780	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J9312_08785	COG0631	protein serine/threonine phosphatase activity
J9312_08790	COG0515	serine threonine protein kinase
J9312_08790	COG2815	serine threonine protein kinase
J9312_08795	COG1162	GTPase activity
J9312_08800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J9312_08805	COG1564	THIamine pyrophosphokinase
J9312_08815	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J9312_08820	COG1302	Protein conserved in bacteria
J9312_08825	COG1461	Dihydroxyacetone kinase
J9312_08830	COG1760	l-serine dehydratase
J9312_08835	COG1760	l-serine dehydratase
J9312_08840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J9312_08845	COG1349	DNA-binding transcription factor activity
J9312_08845	COG2050	protein possibly involved in aromatic compounds catabolism
J9312_08850	COG0416	fatty acid biosynthetic process
J9312_08855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J9312_08860	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_08870	COG0571	ribonuclease III activity
J9312_08875	COG1196	nuclear chromosome segregation
J9312_08880	COG0552	protein localization to endoplasmic reticulum
J9312_08890	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
J9312_08895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J9312_08900	COG0228	four-way junction DNA binding
J9312_08905	COG1837	Belongs to the UPF0109 family
J9312_08915	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J9312_08920	COG0336	Belongs to the RNA methyltransferase TrmD family
J9312_08925	COG0335	large ribosomal subunit rRNA binding
J9312_08930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J9312_08935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J9312_08945	COG2257	FlhB HrpN YscU SpaS Family
J9312_08950	COG0045	succinate-CoA ligase (ADP-forming) activity
J9312_08955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J9312_08960	COG0758	DNA mediated transformation
J9312_08965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J9312_08970	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
J9312_08975	COG4974	Belongs to the 'phage' integrase family
J9312_08980	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J9312_08985	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J9312_08990	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
J9312_08995	COG1815	bacterial-type flagellum-dependent cell motility
J9312_09000	COG1558	bacterial-type flagellum-dependent cell motility
J9312_09005	COG1677	Flagellar hook-basal body complex protein FliE
J9312_09010	COG1766	The M ring may be actively involved in energy transduction
J9312_09015	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J9312_09020	COG1317	bacterial-type flagellum organization
J9312_09025	COG1157	protein secretion by the type III secretion system
J9312_09030	COG2882	bacterial-type flagellum organization
J9312_09035	COG3334	PFAM MgtE intracellular
J9312_09040	COG3144	bacterial-type flagellum assembly
J9312_09045	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J9312_09050	COG4786	Flagellar basal body rod
J9312_09055	COG1582	Flagellar protein (FlbD)
J9312_09060	COG1580	Controls the rotational direction of flagella during chemotaxis
J9312_09065	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J9312_09070	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J9312_09070	COG1776	CheC inhibitor of MCP methylation
J9312_09075	COG2201	protein-glutamate methylesterase activity
J9312_09080	COG3190	flagellar
J9312_09085	COG1338	Plays a role in the flagellum-specific transport system
J9312_09090	COG1987	bacterial-type flagellum assembly
J9312_09095	COG1684	flagellar biosynthetic protein fliR
J9312_09100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J9312_09105	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J9312_09110	COG1419	protein localization to endoplasmic reticulum
J9312_09115	COG0455	bacterial-type flagellum organization
J9312_09120	COG2201	protein-glutamate methylesterase activity
J9312_09125	COG2198	Histidine kinase
J9312_09125	COG0643	Histidine kinase
J9312_09130	COG0835	chemotaxis
J9312_09135	COG1776	CheC inhibitor of MCP methylation
J9312_09140	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J9312_09145	COG1191	sigma factor activity
J9312_09155	COG0052	Belongs to the universal ribosomal protein uS2 family
J9312_09160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J9312_09165	COG0528	UMP kinase activity
J9312_09170	COG0233	cytoplasmic translational termination
J9312_09175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J9312_09180	COG4589	Belongs to the CDS family
J9312_09185	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J9312_09190	COG0750	zinc metalloprotease
J9312_09195	COG0442	prolyl-tRNA aminoacylation
J9312_09200	COG2176	DNA-directed DNA polymerase activity
J9312_09205	COG0779	Required for maturation of 30S ribosomal subunits
J9312_09210	COG0195	Participates in both transcription termination and antitermination
J9312_09215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
J9312_09220	COG1358	cellular component organization or biogenesis
J9312_09225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J9312_09230	COG1550	Protein conserved in bacteria
J9312_09235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J9312_09240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J9312_09245	COG0196	riboflavin kinase activity
J9312_09250	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J9312_09255	COG1185	polyribonucleotide nucleotidyltransferase activity
J9312_09260	COG0726	polysaccharide deacetylase
J9312_09265	COG0612	Peptidase, M16
J9312_09270	COG1873	PFAM PRC-barrel domain
J9312_09275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J9312_09280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J9312_09285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J9312_09290	COG0527	aspartate kinase activity
J9312_09295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J9312_09300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J9312_09305	COG0740	serine-type endopeptidase activity
J9312_09315	COG1674	ftsk spoiiie
J9312_09315	COG4980	gas vesicle protein
J9312_09320	COG2188	Transcriptional regulator
J9312_09325	COG2814	Major facilitator Superfamily
J9312_09330	COG0612	Peptidase, M16
J9312_09335	COG0612	Peptidase, M16
J9312_09340	COG0300	oxidoreductase activity
J9312_09355	COG1426	Protein conserved in bacteria
J9312_09360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J9312_09365	COG1546	Belongs to the CinA family
J9312_09365	COG1058	Belongs to the CinA family
J9312_09370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J9312_09375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J9312_09380	COG1418	mRNA catabolic process
J9312_09385	COG1692	metallophosphoesterase
J9312_09390	COG2359	stage V sporulation protein S
J9312_09395	COG1063	alcohol dehydrogenase
J9312_09400	COG0156	8-amino-7-oxononanoate synthase activity
J9312_09405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J9312_09410	COG4550	Control of competence regulator ComK, YlbF/YmcA
J9312_09420	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J9312_09425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J9312_09545	COG3226	Transcriptional regulator
J9312_09555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_09560	COG1404	Belongs to the peptidase S8 family
J9312_09570	COG4195	phage-related replication protein
J9312_09575	COG1764	response to oxidative stress
J9312_09580	COG2076	Multidrug Resistance protein
J9312_09585	COG2076	Multidrug Resistance protein
J9312_09600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J9312_09605	COG1923	regulation of RNA biosynthetic process
J9312_09620	COG1780	Probably involved in ribonucleotide reductase function
J9312_09625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J9312_09630	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J9312_09635	COG4112	unkown
J9312_09640	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_09645	COG0464	growth
J9312_09650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J9312_09655	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
J9312_09660	COG0789	Transcriptional regulator
J9312_09665	COG0174	glutamine synthetase
J9312_09685	COG5444	nuclease activity
J9312_09710	COG4282	regulation of fungal-type cell wall biogenesis
J9312_09720	COG3328	transposase activity
J9312_09730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_09745	COG3655	Transcriptional regulator
J9312_09770	COG0135	phosphoribosylanthranilate isomerase activity
J9312_09775	COG2211	Major facilitator Superfamily
J9312_09780	COG3507	Belongs to the glycosyl hydrolase 43 family
J9312_09785	COG1940	carbohydrate kinase activity
J9312_09790	COG2115	Belongs to the xylose isomerase family
J9312_09795	COG1070	Carbohydrate kinase
J9312_09805	COG1525	nuclease
J9312_09810	COG2814	Major facilitator Superfamily
J9312_09815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J9312_09830	COG0756	dUTP diphosphatase activity
J9312_09870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J9312_09880	COG3832	glyoxalase III activity
J9312_09920	COG4195	phage-related replication protein
J9312_09930	COG0346	lactoylglutathione lyase activity
J9312_09935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J9312_09940	COG1388	LysM domain
J9312_09945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J9312_09950	COG4224	UPF0291 protein
J9312_09955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J9312_09965	COG3763	UPF0154 protein
J9312_09975	COG0785	Cytochrome C biogenesis protein
J9312_09980	COG2201	protein-glutamate methylesterase activity
J9312_09985	COG4846	Membrane protein involved in cytochrome C biogenesis
J9312_09995	COG0071	Belongs to the small heat shock protein (HSP20) family
J9312_10010	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J9312_10015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_10035	COG0824	Thioesterase
J9312_10045	COG4841	protein insertion into membrane
J9312_10050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J9312_10055	COG1832	CoA-binding protein
J9312_10060	COG0187	DNA topoisomerase II activity
J9312_10065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J9312_10075	COG1115	amino acid carrier protein
J9312_10080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J9312_10090	COG5520	Belongs to the glycosyl hydrolase 30 family
J9312_10100	COG2246	polysaccharide biosynthetic process
J9312_10105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J9312_10110	COG0586	Pfam SNARE associated Golgi protein
J9312_10115	COG2404	hydrolase activity, acting on ester bonds
J9312_10120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J9312_10125	COG1024	Enoyl-CoA hydratase
J9312_10130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J9312_10135	COG0511	ligase activity, forming carbon-carbon bonds
J9312_10140	COG0439	Biotin carboxylase
J9312_10145	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_10150	COG1960	acyl-CoA dehydrogenase activity
J9312_10160	COG1649	PFAM Uncharacterised BCR, COG1649
J9312_10175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_10180	COG2027	D-alanyl-D-alanine carboxypeptidase
J9312_10185	COG2017	converts alpha-aldose to the beta-anomer
J9312_10190	COG0534	Mate efflux family protein
J9312_10210	COG0582	viral genome integration into host DNA
J9312_10215	COG0166	Belongs to the GPI family
J9312_10220	COG0405	Gamma-glutamyltransferase
J9312_10225	COG0583	DNA-binding transcription factor activity
J9312_10230	COG0604	alcohol dehydrogenase
J9312_10235	COG0493	'glutamate synthase
J9312_10240	COG0067	glutamate synthase
J9312_10240	COG0070	glutamate synthase
J9312_10240	COG0069	glutamate synthase activity
J9312_10245	COG0583	DNA-binding transcription factor activity
J9312_10250	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J9312_10255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J9312_10265	COG0300	oxidoreductase activity
J9312_10270	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
J9312_10280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_10295	COG1131	(ABC) transporter
J9312_10305	COG2814	Major facilitator Superfamily
J9312_10315	COG2323	membrane
J9312_10320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J9312_10325	COG3328	transposase activity
J9312_10355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_10375	COG5444	nuclease activity
J9312_10380	COG4282	regulation of fungal-type cell wall biogenesis
J9312_10385	COG1231	oxidoreductase activity
J9312_10390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9312_10395	COG0662	Cupin 2, conserved barrel domain protein
J9312_10395	COG2207	Transcriptional regulator
J9312_10400	COG0456	acetyltransferase
J9312_10405	COG1309	transcriptional regulator
J9312_10410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_10415	COG3708	Transcriptional regulator
J9312_10420	COG2378	regulation of single-species biofilm formation
J9312_10430	COG0640	Transcriptional regulator
J9312_10435	COG0741	lytic transglycosylase activity
J9312_10440	COG2322	membrane
J9312_10455	COG1619	proteins homologs of microcin C7 resistance protein MccF
J9312_10460	COG3239	Fatty acid desaturase
J9312_10465	COG4585	Histidine kinase
J9312_10470	COG2197	response regulator
J9312_10475	COG1388	LysM domain
J9312_10475	COG3584	3D domain protein
J9312_10480	COG0514	ATP-dependent DNA helicase (RecQ)
J9312_10490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J9312_10495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J9312_10510	COG0071	Belongs to the small heat shock protein (HSP20) family
J9312_10535	COG1012	belongs to the aldehyde dehydrogenase family
J9312_10540	COG1657	PFAM Prenyltransferase squalene oxidase
J9312_10545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J9312_10550	COG0733	neurotransmitter:sodium symporter activity
J9312_10555	COG0385	Bile acid
J9312_10560	COG0508	dehydrogenase complex catalyzes the overall conversion of
J9312_10565	COG0567	Dehydrogenase, E1 component
J9312_10570	COG4548	von Willebrand factor, type A
J9312_10575	COG0714	Associated with various cellular activities
J9312_10580	COG2032	superoxide dismutase activity
J9312_10585	COG1388	LysM domain
J9312_10585	COG0791	NLP P60 protein
J9312_10590	COG1819	glycosyl
J9312_10595	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J9312_10600	COG0534	Mate efflux family protein
J9312_10605	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_10610	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J9312_10615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J9312_10625	COG2962	Rard protein
J9312_10645	COG1942	4-Oxalocrotonate Tautomerase
J9312_10650	COG1733	regulation of RNA biosynthetic process
J9312_10655	COG0778	Nitroreductase
J9312_10665	COG3409	Peptidoglycan-binding domain 1 protein
J9312_10665	COG0793	Belongs to the peptidase S41A family
J9312_10670	COG2226	methyltransferase
J9312_10680	COG1876	peptidase activity
J9312_10685	COG0813	purine-nucleoside phosphorylase activity
J9312_10700	COG0671	phosphoesterase, PA-phosphatase related
J9312_10720	COG4479	Belongs to the UPF0346 family
J9312_10730	COG1509	lysine 2,3-aminomutase activity
J9312_10735	COG0456	acetyltransferase
J9312_10740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J9312_10745	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J9312_10750	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J9312_10755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J9312_10770	COG0456	acetyltransferase
J9312_10775	COG0463	Glycosyl transferase, family 2
J9312_10790	COG4641	Protein conserved in bacteria
J9312_10795	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
J9312_10800	COG1086	Polysaccharide biosynthesis protein
J9312_10805	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J9312_10810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J9312_10815	COG1846	Transcriptional regulator
J9312_10820	COG0534	Mate efflux family protein
J9312_10830	COG4698	Protein conserved in bacteria
J9312_10835	COG2755	lipolytic protein G-D-S-L family
J9312_10840	COG1999	signal sequence binding
J9312_10850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J9312_10855	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J9312_10860	COG1272	protein, Hemolysin III
J9312_10865	COG0204	Acyl-transferase
J9312_10870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J9312_10875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J9312_10885	COG2521	methyltransferase
J9312_10885	COG2136	Putative SAM-dependent methyltransferase
J9312_10895	COG0129	dihydroxy-acid dehydratase activity
J9312_10900	COG1413	lyase activity
J9312_10905	COG1418	mRNA catabolic process
J9312_10910	COG0386	Belongs to the glutathione peroxidase family
J9312_10915	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J9312_10920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J9312_10930	COG1278	Cold shock
J9312_10950	COG0328	RNA-DNA hybrid ribonuclease activity
J9312_10955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J9312_10960	COG0328	RNA-DNA hybrid ribonuclease activity
J9312_10970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J9312_10985	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J9312_10995	COG1755	Isoprenylcysteine carboxyl methyltransferase
J9312_11000	COG3424	synthase
J9312_11005	COG2233	PERMEase
J9312_11010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J9312_11015	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J9312_11025	COG0800	Aldolase
J9312_11030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9312_11035	COG1609	Transcriptional regulator
J9312_11040	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
J9312_11045	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_11050	COG1199	ATP-dependent helicase activity
J9312_11065	COG0116	Belongs to the methyltransferase superfamily
J9312_11080	COG4474	Belongs to the UPF0398 family
J9312_11100	COG1111	helicase
J9312_11100	COG1205	dead DEAH box helicase
J9312_11105	COG2190	(PTS) system
J9312_11110	COG0071	Belongs to the small heat shock protein (HSP20) family
J9312_11145	COG3331	DNA recombination
J9312_11150	COG4499	WXG100 protein secretion system (Wss), protein YukC
J9312_11150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J9312_11160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J9312_11165	COG3935	DnaD domain protein
J9312_11170	COG0017	Asparaginyl-tRNA synthetase
J9312_11175	COG0436	Aminotransferase
J9312_11180	COG5353	protein conserved in bacteria
J9312_11190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J9312_11190	COG1199	ATP-dependent helicase activity
J9312_11195	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J9312_11200	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J9312_11205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J9312_11210	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J9312_11210	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J9312_11215	COG0617	tRNA 3'-terminal CCA addition
J9312_11220	COG0438	transferase activity, transferring glycosyl groups
J9312_11225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J9312_11230	COG1803	Methylglyoxal synthase
J9312_11235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J9312_11240	COG1694	Mazg nucleotide pyrophosphohydrolase
J9312_11245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_11255	COG4347	Protein of unknown function (DUF1405)
J9312_11260	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J9312_11260	COG2010	Cytochrome c
J9312_11265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J9312_11270	COG0723	plastoquinol--plastocyanin reductase activity
J9312_11280	COG5582	Belongs to the UPF0302 family
J9312_11285	COG0457	Tetratricopeptide repeat
J9312_11290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J9312_11295	COG0287	Prephenate dehydrogenase
J9312_11305	COG0159	tryptophan synthase activity
J9312_11310	COG0133	tryptophan synthase activity
J9312_11315	COG0135	phosphoribosylanthranilate isomerase activity
J9312_11325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J9312_11330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J9312_11335	COG4401	Chorismate mutase type I
J9312_11340	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J9312_11345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J9312_11350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J9312_11355	COG0105	UTP biosynthetic process
J9312_11360	COG0142	geranyltranstransferase activity
J9312_11365	COG2226	methyltransferase
J9312_11370	COG0142	geranyltranstransferase activity
J9312_11380	COG0302	gtp cyclohydrolase
J9312_11385	COG0776	regulation of translation
J9312_11390	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J9312_11405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J9312_11410	COG1160	GTP binding
J9312_11440	COG1304	FMN binding
J9312_11445	COG0539	negative regulation of cytoplasmic translation
J9312_11450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J9312_11460	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
J9312_11465	COG2959	enzyme of heme biosynthesis
J9312_11470	COG3773	Cell wall hydrolase
J9312_11470	COG3409	Peptidoglycan-binding domain 1 protein
J9312_11475	COG2339	peptidase activity
J9312_11480	COG0492	ferredoxin-NADP+ reductase activity
J9312_11485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J9312_11490	COG4862	establishment of competence for transformation
J9312_11495	COG1408	metallophosphoesterase
J9312_11505	COG1388	LysM domain
J9312_11510	COG1266	CAAX protease self-immunity
J9312_11515	COG0514	ATP-dependent DNA helicase (RecQ)
J9312_11520	COG4955	Helix-turn-helix domain
J9312_11525	COG1141	Ferredoxin
J9312_11530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
J9312_11535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J9312_11540	COG0710	3-dehydroquinate dehydratase activity
J9312_11550	COG1595	DNA-templated transcription, initiation
J9312_11555	COG5002	protein histidine kinase activity
J9312_11560	COG0745	RESPONSE REGULATOR receiver
J9312_11565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J9312_11570	COG1333	cytochrome c biogenesis protein
J9312_11575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_11580	COG1187	pseudouridine synthase activity
J9312_11585	COG0700	Nucleoside recognition
J9312_11590	COG2715	membrane protein required for spore maturation
J9312_11595	COG1686	Belongs to the peptidase S11 family
J9312_11605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J9312_11610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J9312_11615	COG1547	Domain of unknown function (DUF309)
J9312_11620	COG0456	acetyltransferase
J9312_11625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J9312_11630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J9312_11630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J9312_11635	COG0307	riboflavin synthase, alpha
J9312_11640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J9312_11640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J9312_11650	COG0681	Belongs to the peptidase S26 family
J9312_11660	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
J9312_11710	COG3328	transposase activity
J9312_11715	COG3012	SEC-C Motif Domain Protein
J9312_11730	COG0457	Tetratricopeptide repeat
J9312_11740	COG3328	transposase activity
J9312_11790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J9312_11800	COG4086	secreted protein
J9312_11805	COG0019	diaminopimelate decarboxylase activity
J9312_11810	COG0697	spore germination
J9312_11825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J9312_11845	COG1191	sigma factor activity
J9312_11850	COG2172	sigma factor antagonist activity
J9312_11855	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_11860	COG1686	Belongs to the peptidase S11 family
J9312_11865	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J9312_11870	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J9312_11875	COG4974	Belongs to the 'phage' integrase family
J9312_11885	COG0735	belongs to the Fur family
J9312_11890	COG1300	Membrane
J9312_11900	COG0281	malic enzyme
J9312_11905	COG1757	Na H antiporter
J9312_11910	COG1027	Aspartate ammonia-lyase
J9312_11915	COG0252	asparaginase activity
J9312_11920	COG1396	sequence-specific DNA binding
J9312_11925	COG1379	DNA repair
J9312_11930	COG0494	nUDIX hydrolase
J9312_11940	COG0667	Aldo Keto reductase
J9312_11950	COG1073	alpha beta
J9312_11960	COG4918	Iron-sulphur cluster biosynthesis
J9312_11965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J9312_11965	COG0456	acetyltransferase
J9312_11970	COG2329	Antibiotic biosynthesis monooxygenase
J9312_11975	COG0456	acetyltransferase
J9312_11985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J9312_11995	COG2211	Major facilitator Superfamily
J9312_12005	COG0346	lactoylglutathione lyase activity
J9312_12010	COG1072	(Pantothenic acid kinase))
J9312_12015	COG3048	D-serine ammonia-lyase activity
J9312_12020	COG0300	oxidoreductase activity
J9312_12025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_12030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J9312_12035	COG4187	Peptidase family M20/M25/M40
J9312_12040	COG1902	pentaerythritol trinitrate reductase activity
J9312_12045	COG0596	Alpha beta hydrolase
J9312_12055	COG1234	tRNA 3'-trailer cleavage
J9312_12060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J9312_12065	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J9312_12070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J9312_12080	COG0706	membrane insertase activity
J9312_12085	COG3361	conserved protein (COG2071)
J9312_12090	COG2195	Cleaves the N-terminal amino acid of tripeptides
J9312_12095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J9312_12100	COG0346	lactoylglutathione lyase activity
J9312_12110	COG1376	ErfK ybiS ycfS ynhG family protein
J9312_12115	COG4129	membrane
J9312_12120	COG1126	abc transporter atp-binding protein
J9312_12125	COG0765	amino acid transport
J9312_12130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J9312_12145	COG1597	lipid kinase activity
J9312_12150	COG2814	Major facilitator Superfamily
J9312_12155	COG4978	Transcriptional regulator
J9312_12155	COG0789	Transcriptional regulator
J9312_12160	COG0508	dehydrogenase complex catalyzes the overall conversion of
J9312_12165	COG0022	dehydrogenase e1 component
J9312_12170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J9312_12175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J9312_12180	COG3426	butyrate kinase activity
J9312_12185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J9312_12190	COG0280	phosphate acetyltransferase
J9312_12195	COG3829	transcription factor binding
J9312_12195	COG3290	protein histidine kinase activity
J9312_12205	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J9312_12210	COG2079	MmgE PrpD family protein
J9312_12215	COG0372	Belongs to the citrate synthase family
J9312_12220	COG1960	acyl-CoA dehydrogenase activity
J9312_12225	COG1250	3-hydroxyacyl-CoA dehydrogenase
J9312_12230	COG0183	Belongs to the thiolase family
J9312_12235	COG0584	glycerophosphoryl diester phosphodiesterase
J9312_12240	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_12255	COG1902	pentaerythritol trinitrate reductase activity
J9312_12260	COG0745	RESPONSE REGULATOR receiver
J9312_12265	COG0750	zinc metalloprotease
J9312_12270	COG0497	DNA recombination
J9312_12275	COG1438	arginine binding
J9312_12280	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J9312_12285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J9312_12290	COG0142	geranyltranstransferase activity
J9312_12295	COG1722	exodeoxyribonuclease VII activity
J9312_12300	COG1570	exodeoxyribonuclease VII activity
J9312_12305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J9312_12310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J9312_12315	COG1302	Protein conserved in bacteria
J9312_12320	COG0439	Biotin carboxylase
J9312_12325	COG0511	ligase activity, forming carbon-carbon bonds
J9312_12365	COG3854	ATPases associated with a variety of cellular activities
J9312_12375	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J9312_12380	COG0006	proline dipeptidase activity
J9312_12385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J9312_12395	COG3872	metal-dependent enzyme
J9312_12405	COG1752	Esterase of the alpha-beta hydrolase superfamily
J9312_12410	COG1321	iron dependent repressor
J9312_12415	COG0095	Lipoate-protein ligase
J9312_12420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J9312_12425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J9312_12430	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J9312_12435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J9312_12440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J9312_12455	COG1396	sequence-specific DNA binding
J9312_12465	COG0681	Belongs to the peptidase S26 family
J9312_12490	COG4940	Competence protein ComGF
J9312_12500	COG4970	Tfp pilus assembly protein FimT
J9312_12505	COG4537	Required for transformation and DNA binding
J9312_12510	COG1459	type II secretion system
J9312_12515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J9312_12520	COG0517	IMP dehydrogenase activity
J9312_12525	COG0598	Magnesium transport protein CorA
J9312_12530	COG1253	flavin adenine dinucleotide binding
J9312_12535	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_12545	COG1393	Belongs to the ArsC family
J9312_12555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_12565	COG0011	TIGRFAM Protein of
J9312_12575	COG2866	Carboxypeptidase
J9312_12580	COG1368	sulfuric ester hydrolase activity
J9312_12585	COG1940	carbohydrate kinase activity
J9312_12590	COG4483	Protein conserved in bacteria
J9312_12595	COG0705	Rhomboid family
J9312_12595	COG0457	Tetratricopeptide repeat
J9312_12605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J9312_12615	COG0438	transferase activity, transferring glycosyl groups
J9312_12630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J9312_12635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J9312_12640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J9312_12645	COG0581	inorganic phosphate transmembrane transporter activity
J9312_12650	COG0573	inorganic phosphate transmembrane transporter activity
J9312_12655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J9312_12660	COG0768	penicillin binding
J9312_12665	COG0477	Major facilitator Superfamily
J9312_12670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J9312_12675	COG2839	Protein conserved in bacteria
J9312_12680	COG5521	maltodextrose utilization protein MalA
J9312_12685	COG1388	LysM domain
J9312_12690	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J9312_12695	COG4709	membrane
J9312_12700	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
J9312_12705	COG0735	belongs to the Fur family
J9312_12710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_12720	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J9312_12725	COG0513	Belongs to the DEAD box helicase family
J9312_12735	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J9312_12740	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J9312_12745	COG2384	SAM-dependent methyltransferase
J9312_12750	COG2010	Cytochrome c
J9312_12755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J9312_12760	COG0358	DNA primase activity
J9312_12765	COG1671	Belongs to the UPF0178 family
J9312_12770	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J9312_12775	COG0517	IMP dehydrogenase activity
J9312_12780	COG0751	glycine-tRNA ligase activity
J9312_12785	COG0752	glycyl-tRNA synthetase alpha subunit
J9312_12790	COG1381	Involved in DNA repair and RecF pathway recombination
J9312_12800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J9312_12805	COG0295	cytidine deaminase activity
J9312_12810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J9312_12815	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J9312_12820	COG1480	7TM receptor with intracellular HD hydrolase
J9312_12825	COG1702	phosphate starvation-inducible protein PhoH
J9312_12830	COG0561	phosphatase activity
J9312_12845	COG4864	UPF0365 protein
J9312_12850	COG1030	water channel activity
J9312_12855	COG1610	YqeY-like protein
J9312_12865	COG1283	sodium-dependent phosphate transmembrane transporter activity
J9312_12870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J9312_12875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J9312_12880	COG2264	protein methyltransferase activity
J9312_12885	COG0484	heat shock protein binding
J9312_12890	COG0443	Heat shock 70 kDa protein
J9312_12895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J9312_12900	COG1420	regulation of RNA biosynthetic process
J9312_12905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J9312_12910	COG0481	GTPase activity
J9312_12920	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_12925	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J9312_12930	COG0268	Binds directly to 16S ribosomal RNA
J9312_12935	COG1466	dna polymerase III delta subunit
J9312_12950	COG0658	competence protein
J9312_12950	COG2333	competence protein COMEC
J9312_12955	COG2131	deaminase
J9312_12960	COG1596	polysaccharide export
J9312_12960	COG1555	photosystem II stabilization
J9312_12965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J9312_12970	COG2226	methyltransferase
J9312_12975	COG0799	negative regulation of ribosome biogenesis
J9312_12980	COG1713	HD superfamily hydrolase involved in NAD metabolism
J9312_12985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J9312_12990	COG1534	Rna-binding protein
J9312_12995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J9312_13000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J9312_13005	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
J9312_13015	COG2755	lipolytic protein G-D-S-L family
J9312_13020	COG3409	Peptidoglycan-binding domain 1 protein
J9312_13020	COG5632	N-Acetylmuramoyl-L-alanine amidase
J9312_13025	COG0398	Pfam SNARE associated Golgi protein
J9312_13030	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J9312_13040	COG3209	COG3209 Rhs family protein
J9312_13060	COG0114	fumarate hydratase activity
J9312_13065	COG0583	DNA-binding transcription factor activity
J9312_13075	COG0457	Tetratricopeptide repeat
J9312_13200	COG4978	Transcriptional regulator
J9312_13200	COG0789	Transcriptional regulator
J9312_13205	COG2814	Major facilitator Superfamily
J9312_13210	COG0456	acetyltransferase
J9312_13215	COG3328	transposase activity
J9312_13220	COG1253	flavin adenine dinucleotide binding
J9312_13230	COG0697	spore germination
J9312_13235	COG0583	DNA-binding transcription factor activity
J9312_13240	COG2072	flavoprotein involved in K transport
J9312_13245	COG1230	cation diffusion facilitator family transporter
J9312_13255	COG1114	Component of the transport system for branched-chain amino acids
J9312_13260	COG1687	branched-chain amino acid
J9312_13270	COG1522	sequence-specific DNA binding
J9312_13275	COG2732	(Barnase) inhibitor
J9312_13280	COG2124	cytochrome p450
J9312_13295	COG1335	isochorismatase
J9312_13315	COG2318	DinB family
J9312_13325	COG2070	2-Nitropropane dioxygenase
J9312_13330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J9312_13350	COG3443	Belongs to the bacterial solute-binding protein 9 family
J9312_13360	COG0667	Aldo Keto reductase
J9312_13365	COG3409	Peptidoglycan-binding domain 1 protein
J9312_13370	COG5566	PFAM Mor transcription activator
J9312_13375	COG0596	Alpha beta hydrolase
J9312_13380	COG4991	sh3 domain protein
J9312_13385	COG4991	sh3 domain protein
J9312_13395	COG0346	lactoylglutathione lyase activity
J9312_13405	COG5577	PFAM Coat F domain
J9312_13410	COG1063	alcohol dehydrogenase
J9312_13420	COG5577	PFAM Coat F domain
J9312_13425	COG0789	Transcriptional regulator
J9312_13435	COG1064	alcohol dehydrogenase
J9312_13440	COG0693	protein deglycase activity
J9312_13445	COG1621	beta-fructofuranosidase activity
J9312_13450	COG3716	PTS system mannose fructose sorbose family IID component
J9312_13455	COG3715	PTS system
J9312_13460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_13465	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_13470	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J9312_13470	COG3933	PFAM sigma-54 factor interaction domain-containing protein
J9312_13480	COG1113	amino acid transport
J9312_13485	COG1280	lysine exporter protein (LysE YggA)
J9312_13490	COG1378	Sugar-specific transcriptional regulator TrmB
J9312_13495	COG1595	DNA-templated transcription, initiation
J9312_13505	COG2755	lipolytic protein G-D-S-L family
J9312_13505	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J9312_13515	COG2124	cytochrome p450
J9312_13515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J9312_13520	COG1309	transcriptional regulator
J9312_13525	COG2226	methyltransferase
J9312_13540	COG2116	formate transmembrane transporter activity
J9312_13545	COG5609	conserved protein (DUF2294)
J9312_13550	COG3383	formate dehydrogenase (NAD+) activity
J9312_13555	COG2427	Protein of unknown function (DUF1641)
J9312_13565	COG0626	cystathionine gamma-synthase activity
J9312_13570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J9312_13575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J9312_13580	COG2226	methyltransferase
J9312_13595	COG0768	penicillin binding
J9312_13600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J9312_13605	COG0572	uridine kinase
J9312_13610	COG0826	peptidase U32
J9312_13615	COG0826	peptidase U32
J9312_13620	COG4122	O-methyltransferase activity
J9312_13625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J9312_13630	COG3906	Belongs to the UPF0473 family
J9312_13635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J9312_13640	COG4472	Bacterial protein of unknown function (DUF965)
J9312_13645	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J9312_13650	COG0628	permease
J9312_13655	COG1126	abc transporter atp-binding protein
J9312_13660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J9312_13665	COG0765	amino acid transport
J9312_13670	COG0765	amino acid transport
J9312_13685	COG3881	PFAM PRC-barrel domain
J9312_13690	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J9312_13695	COG0457	Tetratricopeptide repeat
J9312_13700	COG0482	sulfurtransferase activity
J9312_13705	COG1104	cysteine desulfurase activity
J9312_13710	COG1959	2 iron, 2 sulfur cluster binding
J9312_13715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J9312_13720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J9312_13730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J9312_13735	COG0124	histidyl-tRNA synthetase
J9312_13745	COG4991	sh3 domain protein
J9312_13745	COG3103	Sh3 type 3 domain protein
J9312_13745	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_13750	COG1490	D-aminoacyl-tRNA deacylase activity
J9312_13755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J9312_13760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J9312_13765	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J9312_13765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J9312_13770	COG5416	Lipopolysaccharide assembly protein A domain
J9312_13775	COG0490	domain, Protein
J9312_13780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J9312_13780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J9312_13790	COG2244	polysaccharide biosynthetic process
J9312_13795	COG2323	membrane
J9312_13805	COG1862	Preprotein translocase
J9312_13810	COG0343	queuine tRNA-ribosyltransferase activity
J9312_13815	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J9312_13825	COG2255	four-way junction helicase activity
J9312_13830	COG0632	four-way junction helicase activity
J9312_13840	COG2814	Major facilitator Superfamily
J9312_13845	COG0673	inositol 2-dehydrogenase activity
J9312_13850	COG2112	serine threonine protein kinase
J9312_13870	COG1115	amino acid carrier protein
J9312_13875	COG0217	transcriptional regulatory protein
J9312_13885	COG1388	LysM domain
J9312_13890	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J9312_13895	COG0157	Belongs to the NadC ModD family
J9312_13900	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J9312_13905	COG1104	cysteine desulfurase activity
J9312_13910	COG1827	regulation of RNA biosynthetic process
J9312_13915	COG0077	Prephenate dehydratase
J9312_13920	COG4492	Belongs to the UPF0735 family
J9312_13925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J9312_13930	COG3290	protein histidine kinase activity
J9312_13940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J9312_13945	COG2868	ribosomal protein
J9312_13950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J9312_13955	COG1994	Peptidase M50
J9312_13960	COG0739	heme binding
J9312_13965	COG2894	cell division
J9312_13970	COG0850	regulation of cytokinetic process
J9312_13975	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J9312_13985	COG1077	Cell shape determining protein MreB Mrl
J9312_13990	COG2003	Belongs to the UPF0758 family
J9312_13995	COG0424	maF-like protein
J9312_14005	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J9312_14010	COG0285	dihydrofolate synthase activity
J9312_14015	COG0525	valine-tRNA ligase activity
J9312_14025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9312_14030	COG1388	LysM domain
J9312_14035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J9312_14040	COG0113	porphobilinogen synthase activity
J9312_14045	COG1587	Uroporphyrinogen-III synthase
J9312_14050	COG0181	hydroxymethylbilane synthase activity
J9312_14055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J9312_14060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J9312_14070	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J9312_14075	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J9312_14080	COG1067	ATP-dependent peptidase activity
J9312_14080	COG0470	DNA polymerase III
J9312_14085	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J9312_14090	COG0544	peptidyl-prolyl cis-trans isomerase activity
J9312_14095	COG0457	Tetratricopeptide repeat
J9312_14095	COG1477	protein flavinylation
J9312_14100	COG0066	3-isopropylmalate dehydratase activity
J9312_14105	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J9312_14110	COG0473	3-isopropylmalate dehydrogenase activity
J9312_14115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J9312_14120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J9312_14125	COG0440	acetolactate synthase activity
J9312_14130	COG0028	Belongs to the TPP enzyme family
J9312_14140	COG0454	-acetyltransferase
J9312_14145	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
J9312_14160	COG0622	Phosphoesterase
J9312_14165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J9312_14170	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J9312_14175	COG5401	PFAM Sporulation and spore germination
J9312_14180	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J9312_14185	COG1846	Transcriptional regulator
J9312_14190	COG2197	response regulator
J9312_14195	COG0824	Thioesterase
J9312_14200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J9312_14205	COG1053	succinate dehydrogenase
J9312_14210	COG2009	succinate dehydrogenase
J9312_14215	COG1719	4-vinyl reductase, 4VR
J9312_14220	COG0527	aspartate kinase activity
J9312_14225	COG0322	excinuclease ABC activity
J9312_14230	COG3118	belongs to the thioredoxin family
J9312_14235	COG3534	alpha-L-arabinofuranosidase
J9312_14240	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
J9312_14245	COG2086	electron transfer activity
J9312_14250	COG1024	Enoyl-CoA hydratase
J9312_14255	COG1309	transcriptional regulator
J9312_14260	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_14265	COG3766	membrane
J9312_14270	COG1193	negative regulation of DNA recombination
J9312_14275	COG1796	DNA polymerase
J9312_14275	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J9312_14280	COG1286	toxin biosynthetic process
J9312_14285	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
J9312_14290	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J9312_14295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9312_14295	COG0072	phenylalanine-tRNA ligase activity
J9312_14300	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J9312_14310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J9312_14320	COG3835	regulator
J9312_14325	COG0277	FAD linked oxidase domain protein
J9312_14330	COG0247	lactate metabolic process
J9312_14335	COG0346	lactoylglutathione lyase activity
J9312_14345	COG1966	Carbon starvation protein
J9312_14350	COG3534	alpha-L-arabinofuranosidase
J9312_14355	COG0395	ABC-type sugar transport system, permease component
J9312_14360	COG1175	transmembrane transport
J9312_14365	COG1653	transport
J9312_14370	COG0371	Dehydrogenase
J9312_14375	COG0647	UMP catabolic process
J9312_14380	COG0235	Class ii aldolase
J9312_14385	COG1069	ribulokinase activity
J9312_14390	COG2160	L-arabinose isomerase activity
J9312_14395	COG3507	Belongs to the glycosyl hydrolase 43 family
J9312_14400	COG1363	Peptidase, m42
J9312_14410	COG3326	Membrane
J9312_14415	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J9312_14420	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J9312_14425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J9312_14435	COG1346	cytolysis
J9312_14440	COG1380	Effector of murein hydrolase LrgA
J9312_14445	COG3279	Response regulator of the LytR AlgR family
J9312_14450	COG3275	phosphorelay sensor kinase activity
J9312_14455	COG1011	Hydrolase
J9312_14460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J9312_14470	COG0398	Pfam SNARE associated Golgi protein
J9312_14475	COG1484	DNA-dependent DNA replication
J9312_14480	COG3611	Membrane attachment protein
J9312_14485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J9312_14490	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
J9312_14495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J9312_14510	COG0656	L-ascorbic acid biosynthetic process
J9312_14515	COG0237	dephospho-CoA kinase activity
J9312_14520	COG1971	Probably functions as a manganese efflux pump
J9312_14525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J9312_14530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J9312_14530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J9312_14535	COG5002	protein histidine kinase activity
J9312_14540	COG0745	RESPONSE REGULATOR receiver
J9312_14545	COG0039	L-malate dehydrogenase activity
J9312_14550	COG0538	isocitrate dehydrogenase activity
J9312_14555	COG0372	Belongs to the citrate synthase family
J9312_14560	COG2707	UPF0756 membrane protein
J9312_14565	COG0628	permease
J9312_14570	COG3030	protein affecting phage T7 exclusion by the F plasmid
J9312_14575	COG0469	pyruvate kinase activity
J9312_14580	COG0205	6-phosphofructokinase activity
J9312_14585	COG0825	malonyl-CoA metabolic process
J9312_14590	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J9312_14595	COG0281	malic enzyme
J9312_14600	COG0587	DNA-directed DNA polymerase activity
J9312_14620	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J9312_14630	COG4109	DRTGG domain
J9312_14635	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
J9312_14640	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_14645	COG0165	Argininosuccinate lyase
J9312_14650	COG0137	argininosuccinate synthase activity
J9312_14655	COG0521	Mo-molybdopterin cofactor biosynthetic process
J9312_14660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J9312_14670	COG0827	DNA restriction-modification system
J9312_14675	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J9312_14680	COG3874	Sporulation protein YtfJ
J9312_14690	COG1714	RDD family
J9312_14695	COG0616	signal peptide processing
J9312_14700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J9312_14705	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J9312_14710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J9312_14720	COG0301	tRNA thio-modification
J9312_14725	COG1104	cysteine desulfurase activity
J9312_14730	COG1114	Component of the transport system for branched-chain amino acids
J9312_14735	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
J9312_14740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J9312_14745	COG1309	transcriptional regulator
J9312_14750	COG1956	GAF domain-containing protein
J9312_14755	COG2203	Gaf domain
J9312_14755	COG2199	diguanylate cyclase activity
J9312_14760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J9312_14765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J9312_14770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J9312_14775	COG0454	-acetyltransferase
J9312_14780	COG0517	IMP dehydrogenase activity
J9312_14785	COG0123	including yeast histone deacetylase and acetoin utilization protein
J9312_14790	COG1360	Flagellar Motor Protein
J9312_14795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J9312_14800	COG1609	Transcriptional regulator
J9312_14805	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
J9312_14805	COG1605	Chorismate mutase
J9312_14810	COG3118	belongs to the thioredoxin family
J9312_14815	COG4980	gas vesicle protein
J9312_14820	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
J9312_14825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J9312_14830	COG1674	ftsk spoiiie
J9312_14835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9312_14840	COG4848	Belongs to the UPF0354 family
J9312_14845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_14860	COG1363	Peptidase, m42
J9312_14865	COG5584	Small secreted protein
J9312_14870	COG0281	malic enzyme
J9312_14875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_14880	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J9312_14890	COG0510	thiamine kinase activity
J9312_14895	COG1523	belongs to the glycosyl hydrolase 13 family
J9312_14900	COG1597	lipid kinase activity
J9312_14910	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J9312_14915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J9312_14920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J9312_14925	COG2252	PERMEase
J9312_14930	COG4473	ABC transporter
J9312_14935	COG1131	(ABC) transporter
J9312_14940	COG1349	DNA-binding transcription factor activity
J9312_14945	COG1187	pseudouridine synthase activity
J9312_14950	COG2244	polysaccharide biosynthetic process
J9312_14955	COG2081	HI0933 family
J9312_14960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J9312_14970	COG5578	integral membrane protein
J9312_14975	COG0673	inositol 2-dehydrogenase activity
J9312_14980	COG1653	transport
J9312_14985	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
J9312_14990	COG4209	transmembrane transport
J9312_14995	COG2207	Transcriptional regulator
J9312_15000	COG1653	transport
J9312_15005	COG0395	ABC-type sugar transport system, permease component
J9312_15010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J9312_15015	COG2124	cytochrome p450
J9312_15020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J9312_15030	COG0156	8-amino-7-oxononanoate synthase activity
J9312_15035	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J9312_15045	COG1073	alpha beta
J9312_15050	COG1609	Transcriptional regulator
J9312_15055	COG1653	transport
J9312_15060	COG1175	transmembrane transport
J9312_15065	COG0395	ABC-type sugar transport system, permease component
J9312_15070	COG1486	melibiose metabolic process
J9312_15075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J9312_15080	COG0495	leucyl-tRNA aminoacylation
J9312_15090	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_15090	COG2202	Pas domain
J9312_15095	COG2814	Major facilitator Superfamily
J9312_15105	COG0577	efflux transmembrane transporter activity
J9312_15110	COG1136	(ABC) transporter
J9312_15115	COG2205	protein histidine kinase activity
J9312_15120	COG0745	RESPONSE REGULATOR receiver
J9312_15125	COG0577	efflux transmembrane transporter activity
J9312_15130	COG1136	(ABC) transporter
J9312_15145	COG1131	(ABC) transporter
J9312_15150	COG1725	Transcriptional regulator
J9312_15165	COG1242	4 iron, 4 sulfur cluster binding
J9312_15170	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J9312_15180	COG2267	carboxylic ester hydrolase activity
J9312_15185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J9312_15190	COG1113	amino acid transport
J9312_15195	COG0367	asparagine synthase
J9312_15200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J9312_15205	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J9312_15215	COG1506	peptidase
J9312_15220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J9312_15225	COG1116	anion transmembrane transporter activity
J9312_15230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J9312_15235	COG0494	nUDIX hydrolase
J9312_15240	COG4824	toxin secretion phage lysis holin
J9312_15245	COG0783	Belongs to the Dps family
J9312_15260	COG1854	S-ribosylhomocysteine lyase activity
J9312_15265	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J9312_15270	COG0288	reversible hydration of carbon dioxide
J9312_15275	COG0254	rRNA binding
J9312_15280	COG1271	oxidase subunit
J9312_15285	COG1294	oxidase, subunit
J9312_15295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J9312_15300	COG1321	iron dependent repressor
J9312_15300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J9312_15305	COG1121	(ABC) transporter
J9312_15310	COG0803	Belongs to the bacterial solute-binding protein 9 family
J9312_15315	COG4948	Mandelate Racemase Muconate Lactonizing
J9312_15320	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_15325	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J9312_15330	COG0596	Alpha beta hydrolase
J9312_15335	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J9312_15340	COG1169	isochorismate synthase
J9312_15345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J9312_15350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J9312_15355	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J9312_15360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J9312_15365	COG0438	transferase activity, transferring glycosyl groups
J9312_15375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9312_15380	COG0438	transferase activity, transferring glycosyl groups
J9312_15385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9312_15390	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
J9312_15395	COG0058	SHG alpha-glucan phosphorylase activity
J9312_15400	COG0297	glycogen (starch) synthase activity
J9312_15405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J9312_15410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J9312_15415	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J9312_15540	COG3859	Proton-coupled thiamine transporter YuaJ
J9312_15545	COG1247	-acetyltransferase
J9312_15550	COG2268	Band 7 protein
J9312_15555	COG1585	Membrane protein implicated in regulation of membrane protease activity
J9312_15560	COG2318	DinB family
J9312_15570	COG1454	alcohol dehydrogenase
J9312_15575	COG1012	belongs to the aldehyde dehydrogenase family
J9312_15580	COG1510	regulation of RNA biosynthetic process
J9312_15595	COG0569	domain protein
J9312_15600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J9312_15605	COG4682	membrane
J9312_15610	COG1705	Flagellar rod assembly protein muramidase FlgJ
J9312_15615	COG0477	Major facilitator Superfamily
J9312_15620	COG5553	Cysteine dioxygenase type I
J9312_15630	COG1968	undecaprenyl-diphosphatase activity
J9312_15635	COG0628	permease
J9312_15640	COG0673	inositol 2-dehydrogenase activity
J9312_15650	COG3254	rhamnose metabolic process
J9312_15655	COG1070	Carbohydrate kinase
J9312_15660	COG1349	DNA-binding transcription factor activity
J9312_15665	COG3347	Dehydrogenase
J9312_15665	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_15675	COG0840	transmembrane signaling receptor activity
J9312_15680	COG0840	transmembrane signaling receptor activity
J9312_15685	COG0840	transmembrane signaling receptor activity
J9312_15700	COG0432	Pfam Uncharacterised protein family UPF0047
J9312_15710	COG0366	Alpha amylase catalytic
J9312_15715	COG1253	flavin adenine dinucleotide binding
J9312_15720	COG2738	Putative neutral zinc metallopeptidase
J9312_15735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J9312_15750	COG0166	Belongs to the GPI family
J9312_15755	COG1979	alcohol dehydrogenase
J9312_15760	COG1979	alcohol dehydrogenase
J9312_15765	COG2155	Conserved Protein
J9312_15770	COG1098	S1 RNA binding domain
J9312_15775	COG0436	Aminotransferase
J9312_15780	COG1522	sequence-specific DNA binding
J9312_15785	COG2267	carboxylic ester hydrolase activity
J9312_15795	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J9312_15800	COG2205	protein histidine kinase activity
J9312_15810	COG5018	Exonuclease
J9312_15815	COG2814	Major facilitator Superfamily
J9312_15820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J9312_15825	COG3011	Protein conserved in bacteria
J9312_15835	COG3290	protein histidine kinase activity
J9312_15840	COG4565	transcriptional regulatory protein
J9312_15845	COG1744	ABC transporter substrate-binding protein PnrA-like
J9312_15850	COG3845	ABC transporter
J9312_15855	COG4603	Belongs to the binding-protein-dependent transport system permease family
J9312_15860	COG1079	Belongs to the binding-protein-dependent transport system permease family
J9312_15865	COG3493	citrate carrier protein
J9312_15875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J9312_15875	COG2111	Na H antiporter
J9312_15880	COG2111	Na H antiporter
J9312_15885	COG1006	Multisubunit Na H antiporter MnhC subunit
J9312_15890	COG0651	ATP synthesis coupled electron transport
J9312_15895	COG1863	multisubunit Na H antiporter MnhE subunit
J9312_15900	COG2212	antiporter activity
J9312_15905	COG1320	monovalent cation:proton antiporter activity
J9312_15910	COG2050	protein possibly involved in aromatic compounds catabolism
J9312_15915	COG2197	response regulator
J9312_15925	COG3328	transposase activity
J9312_15940	COG0142	geranyltranstransferase activity
J9312_15960	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J9312_15965	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J9312_15970	COG1335	isochorismatase
J9312_15975	COG5506	Protein of unknown function (DUF1694)
J9312_15990	COG0628	permease
J9312_16005	COG1418	mRNA catabolic process
J9312_16010	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_16020	COG1511	domain protein
J9312_16025	COG1674	ftsk spoiiie
J9312_16025	COG0433	COG0433 Predicted ATPase
J9312_16030	COG4499	WXG100 protein secretion system (Wss), protein YukC
J9312_16035	COG5417	Belongs to the EsaB family
J9312_16040	COG4842	Belongs to the WXG100 family
J9312_16045	COG2508	Transcriptional regulator
J9312_16045	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
J9312_16050	COG0686	Belongs to the AlaDH PNT family
J9312_16055	COG5634	Uncharacterized conserved protein (DUF2278)
J9312_16060	COG3251	PFAM MbtH domain protein
J9312_16065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_16070	COG3433	isochorismatase activity
J9312_16070	COG1535	isochorismatase
J9312_16075	COG1021	2,3-dihydroxybenzoate-AMP ligase
J9312_16080	COG1169	isochorismate synthase
J9312_16085	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_16090	COG2819	hydrolase of the alpha beta superfamily
J9312_16095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J9312_16100	COG1268	BioY protein
J9312_16105	COG2056	Na+-H+ antiporter family
J9312_16110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J9312_16115	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
J9312_16120	COG3584	3D domain protein
J9312_16135	COG1252	NADH dehydrogenase
J9312_16140	COG0492	ferredoxin-NADP+ reductase activity
J9312_16150	COG0516	GMP reductase activity
J9312_16155	COG2808	Putative FMN-binding domain
J9312_16160	COG0456	acetyltransferase
J9312_16165	COG0316	Belongs to the HesB IscA family
J9312_16170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J9312_16175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J9312_16180	COG4844	belongs to the
J9312_16185	COG1252	NADH dehydrogenase
J9312_16190	COG4837	Protein of unknown function (DUF1462)
J9312_16195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J9312_16200	COG0823	Involved in the tonB-independent uptake of proteins
J9312_16200	COG1506	peptidase
J9312_16200	COG4946	Tricorn protease homolog
J9312_16205	COG0083	homoserine kinase activity
J9312_16210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J9312_16215	COG0460	homoserine dehydrogenase
J9312_16220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9312_16225	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J9312_16230	COG0647	UMP catabolic process
J9312_16235	COG2445	Protein of unknown function DUF86
J9312_16240	COG4470	Protein conserved in bacteria
J9312_16250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J9312_16255	COG0739	heme binding
J9312_16265	COG3377	Domain of unknown function (DUF1805)
J9312_16270	COG0737	Belongs to the 5'-nucleotidase family
J9312_16275	COG0730	response to heat
J9312_16280	COG1801	Protein of unknown function DUF72
J9312_16290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J9312_16295	COG2508	Transcriptional regulator
J9312_16300	COG2233	PERMEase
J9312_16305	COG2233	PERMEase
J9312_16310	COG3648	Uricase
J9312_16310	COG3195	allantoin biosynthetic process
J9312_16315	COG2351	hydroxyisourate hydrolase activity
J9312_16325	COG2080	2 iron, 2 sulfur cluster binding
J9312_16330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J9312_16335	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J9312_16340	COG2068	MobA-Related Protein
J9312_16345	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J9312_16350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J9312_16355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J9312_16365	COG2356	endonuclease I
J9312_16370	COG3842	ATPase activity
J9312_16375	COG2188	Transcriptional regulator
J9312_16380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9312_16385	COG0395	ABC-type sugar transport system, permease component
J9312_16390	COG1175	transmembrane transport
J9312_16395	COG1653	transport
J9312_16400	COG2222	sugar isomerase
J9312_16405	COG0322	excinuclease ABC activity
J9312_16410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J9312_16430	COG0346	lactoylglutathione lyase activity
J9312_16435	COG0640	Transcriptional regulator
J9312_16440	COG0719	Fe-S assembly protein
J9312_16445	COG0822	iron-sulfur transferase activity
J9312_16450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J9312_16455	COG0719	Fe-S assembly protein
J9312_16460	COG0396	ATPase activity
J9312_16470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J9312_16475	COG1464	Belongs to the NlpA lipoprotein family
J9312_16480	COG2011	ABC-type metal ion transport system permease component
J9312_16485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J9312_16495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_16500	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J9312_16510	COG0509	glycine decarboxylation via glycine cleavage system
J9312_16515	COG1393	Belongs to the ArsC family
J9312_16520	COG1960	acyl-CoA dehydrogenase activity
J9312_16525	COG0183	Belongs to the thiolase family
J9312_16530	COG1024	Enoyl-CoA hydratase
J9312_16530	COG1250	3-hydroxyacyl-CoA dehydrogenase
J9312_16550	COG5577	PFAM Coat F domain
J9312_16555	COG1846	Transcriptional regulator
J9312_16560	COG0477	Major facilitator Superfamily
J9312_16565	COG1942	4-Oxalocrotonate Tautomerase
J9312_16570	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_16575	COG0583	DNA-binding transcription factor activity
J9312_16585	COG1120	ATPase activity
J9312_16600	COG3328	transposase activity
J9312_16610	COG1131	(ABC) transporter
J9312_16655	COG0783	Belongs to the Dps family
J9312_16660	COG3328	transposase activity
J9312_16665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9312_16670	COG0745	RESPONSE REGULATOR receiver
J9312_16675	COG2205	protein histidine kinase activity
J9312_16675	COG2770	Histidine kinase
J9312_16685	COG1309	transcriptional regulator
J9312_16690	COG0114	fumarate hydratase activity
J9312_16700	COG0697	spore germination
J9312_16705	COG0814	amino acid
J9312_16715	COG2197	response regulator
J9312_16720	COG4585	Histidine kinase
J9312_16725	COG4758	membrane
J9312_16730	COG3595	metallopeptidase activity
J9312_16735	COG1842	Phage shock protein A
J9312_16740	COG4758	membrane
J9312_16745	COG2814	Major facilitator Superfamily
J9312_16750	COG2096	Adenosyltransferase
J9312_16755	COG1120	ATPase activity
J9312_16760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_16765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_16770	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_16775	COG3386	PFAM SMP-30 Gluconolaconase
J9312_16780	COG2205	protein histidine kinase activity
J9312_16785	COG0745	RESPONSE REGULATOR receiver
J9312_16795	COG1191	sigma factor activity
J9312_16805	COG2140	Oxalate decarboxylase
J9312_16815	COG0577	efflux transmembrane transporter activity
J9312_16820	COG1136	(ABC) transporter
J9312_16825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J9312_16830	COG1120	ATPase activity
J9312_16835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_16840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_16845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_16850	COG0531	amino acid
J9312_16860	COG1988	membrane-bound metal-dependent
J9312_16865	COG1368	sulfuric ester hydrolase activity
J9312_16870	COG1910	domain protein
J9312_16875	COG0725	ABC transporter, periplasmic molybdate-binding protein
J9312_16880	COG4149	molybdate abc transporter
J9312_16885	COG0656	L-ascorbic acid biosynthetic process
J9312_16895	COG0025	NhaP-type Na H and K H
J9312_16900	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J9312_16905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J9312_16910	COG3973	AAA domain
J9312_16920	COG2860	membrane
J9312_16925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J9312_16930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J9312_16935	COG2217	Heavy metal translocating P-type atpase
J9312_16940	COG2217	Heavy metal translocating P-type atpase
J9312_16945	COG2608	mercury ion transmembrane transporter activity
J9312_16950	COG1937	Protein conserved in bacteria
J9312_16960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J9312_16965	COG1289	transmembrane transporter activity
J9312_16975	COG2076	Multidrug Resistance protein
J9312_16980	COG1309	transcriptional regulator
J9312_16985	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_16995	COG5444	nuclease activity
J9312_17010	COG5632	N-Acetylmuramoyl-L-alanine amidase
J9312_17010	COG3409	Peptidoglycan-binding domain 1 protein
J9312_17015	COG4824	toxin secretion phage lysis holin
J9312_17040	COG3942	CHAP domain
J9312_17040	COG1705	Flagellar rod assembly protein muramidase FlgJ
J9312_17295	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J9312_17300	COG0557	exoribonuclease II activity
J9312_17305	COG1647	Serine aminopeptidase, S33
J9312_17310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J9312_17315	COG0596	Alpha beta hydrolase
J9312_17320	COG1476	TRANSCRIPTIONal
J9312_17325	COG1396	sequence-specific DNA binding
J9312_17330	COG1396	sequence-specific DNA binding
J9312_17335	COG1733	regulation of RNA biosynthetic process
J9312_17340	COG0840	transmembrane signaling receptor activity
J9312_17345	COG1174	glycine betaine transport
J9312_17350	COG1732	Glycine betaine
J9312_17355	COG1174	glycine betaine transport
J9312_17360	COG1125	glycine betaine transport
J9312_17360	COG0517	IMP dehydrogenase activity
J9312_17365	COG1510	regulation of RNA biosynthetic process
J9312_17370	COG1174	glycine betaine transport
J9312_17375	COG1732	Glycine betaine
J9312_17380	COG1174	glycine betaine transport
J9312_17385	COG1125	glycine betaine transport
J9312_17385	COG0517	IMP dehydrogenase activity
J9312_17390	COG1510	regulation of RNA biosynthetic process
J9312_17395	COG2095	MarC family integral membrane protein
J9312_17405	COG3064	Membrane
J9312_17410	COG4640	response to antibiotic
J9312_17415	COG0456	acetyltransferase
J9312_17420	COG0148	phosphopyruvate hydratase activity
J9312_17425	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J9312_17430	COG0149	triose-phosphate isomerase activity
J9312_17435	COG0126	phosphoglycerate kinase activity
J9312_17440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J9312_17445	COG2390	Transcriptional regulator
J9312_17450	COG2814	Major facilitator Superfamily
J9312_17455	COG1609	Transcriptional regulator
J9312_17460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J9312_17470	COG0583	DNA-binding transcription factor activity
J9312_17475	COG0697	spore germination
J9312_17480	COG1113	amino acid transport
J9312_17485	COG3858	chitin binding
J9312_17490	COG1556	Lactate utilization protein
J9312_17495	COG1139	Iron-sulfur cluster binding protein
J9312_17500	COG0247	lactate metabolic process
J9312_17505	COG2197	response regulator
J9312_17510	COG4585	Histidine kinase
J9312_17515	COG0842	Transport permease protein
J9312_17520	COG1131	(ABC) transporter
J9312_17525	COG0596	Alpha beta hydrolase
J9312_17530	COG2208	phosphoserine phosphatase activity
J9312_17535	COG3867	Arabinogalactan endo-beta-1,4-galactanase
J9312_17540	COG1874	Beta-galactosidase
J9312_17545	COG3833	ABC-type maltose transport systems, permease component
J9312_17550	COG1175	transmembrane transport
J9312_17555	COG2182	Extracellular solute-binding protein
J9312_17560	COG1609	Transcriptional regulator
J9312_17565	COG2186	Transcriptional regulator
J9312_17570	COG1620	l-lactate permease
J9312_17575	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J9312_17585	COG5039	Polysaccharide pyruvyl transferase
J9312_17590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J9312_17595	COG0110	maltose O-acetyltransferase activity
J9312_17600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J9312_17605	COG2244	polysaccharide biosynthetic process
J9312_17610	COG1216	Glycosyl transferase, family 2
J9312_17615	COG5039	Polysaccharide pyruvyl transferase
J9312_17620	COG1216	Glycosyl transferase, family 2
J9312_17630	COG0438	transferase activity, transferring glycosyl groups
J9312_17635	COG1215	transferase activity, transferring glycosyl groups
J9312_17640	COG0438	transferase activity, transferring glycosyl groups
J9312_17645	COG1086	Polysaccharide biosynthesis protein
J9312_17650	COG0489	protein tyrosine kinase activity
J9312_17655	COG3944	biosynthesis protein
J9312_17660	COG1396	sequence-specific DNA binding
J9312_17665	COG2272	Belongs to the type-B carboxylesterase lipase family
J9312_17675	COG3479	Phenolic acid decarboxylase
J9312_17685	COG1794	racemase activity, acting on amino acids and derivatives
J9312_17695	COG1621	beta-fructofuranosidase activity
J9312_17700	COG1621	beta-fructofuranosidase activity
J9312_17705	COG0531	amino acid
J9312_17710	COG1309	transcriptional regulator
J9312_17715	COG2076	Multidrug Resistance protein
J9312_17720	COG2076	Multidrug Resistance protein
J9312_17740	COG1674	ftsk spoiiie
J9312_17760	COG1388	LysM domain
J9312_17760	COG3409	Peptidoglycan-binding domain 1 protein
J9312_17760	COG5632	N-Acetylmuramoyl-L-alanine amidase
J9312_17795	COG1705	Flagellar rod assembly protein muramidase FlgJ
J9312_17875	COG0582	viral genome integration into host DNA
J9312_17985	COG4974	Belongs to the 'phage' integrase family
J9312_17995	COG0740	serine-type endopeptidase activity
J9312_18000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J9312_18005	COG0366	Alpha amylase catalytic
J9312_18010	COG1554	hydrolase, family 65, central catalytic
J9312_18020	COG3833	ABC-type maltose transport systems, permease component
J9312_18025	COG1175	transmembrane transport
J9312_18030	COG2182	Extracellular solute-binding protein
J9312_18040	COG1609	Transcriptional regulator
J9312_18045	COG1611	Belongs to the LOG family
J9312_18055	COG0659	secondary active sulfate transmembrane transporter activity
J9312_18060	COG0288	reversible hydration of carbon dioxide
J9312_18065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J9312_18070	COG0577	efflux transmembrane transporter activity
J9312_18075	COG1136	(ABC) transporter
J9312_18080	COG5002	protein histidine kinase activity
J9312_18085	COG0745	RESPONSE REGULATOR receiver
J9312_18095	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J9312_18100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_18105	COG1481	regulation of sporulation
J9312_18110	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J9312_18115	COG1660	Displays ATPase and GTPase activities
J9312_18120	COG1051	belongs to the nudix hydrolase family
J9312_18125	COG0492	ferredoxin-NADP+ reductase activity
J9312_18130	COG0791	NLP P60 protein
J9312_18130	COG3883	PFAM NLP P60 protein
J9312_18135	COG0457	Tetratricopeptide repeat
J9312_18140	COG1132	(ABC) transporter
J9312_18160	COG0140	phosphoribosyl-ATP diphosphatase activity
J9312_18160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J9312_18165	COG0107	imidazoleglycerol-phosphate synthase activity
J9312_18170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J9312_18175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J9312_18180	COG0131	Imidazoleglycerol-phosphate dehydratase
J9312_18185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J9312_18190	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J9312_18195	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
J9312_18200	COG4990	cell redox homeostasis
J9312_18205	COG5297	Belongs to the glycosyl hydrolase family 6
J9312_18210	COG0110	maltose O-acetyltransferase activity
J9312_18215	COG0546	phosphoglycolate phosphatase activity
J9312_18220	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J9312_18225	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J9312_18230	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J9312_18235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J9312_18240	COG0363	glucosamine-6-phosphate deaminase activity
J9312_18245	COG2188	Transcriptional regulator
J9312_18250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J9312_18255	COG1950	PFAM Membrane protein of
J9312_18260	COG1983	PspC domain protein
J9312_18265	COG3595	metallopeptidase activity
J9312_18280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J9312_18285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J9312_18290	COG0556	nucleotide-excision repair
J9312_18295	COG4897	Protein conserved in bacteria
J9312_18300	COG0574	Belongs to the PEP-utilizing enzyme family
J9312_18300	COG3848	Pyruvate phosphate dikinase
J9312_18305	COG1309	transcriptional regulator
J9312_18310	COG2814	Major facilitator Superfamily
J9312_18315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9312_18325	COG3409	Peptidoglycan-binding domain 1 protein
J9312_18325	COG0793	Belongs to the peptidase S41A family
J9312_18330	COG2177	Part of the ABC transporter FtsEX involved in
J9312_18335	COG2884	Cell division ATP-binding protein ftsE
J9312_18340	COG2010	Cytochrome c
J9312_18345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_18355	COG0653	protein targeting
J9312_18360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J9312_18375	COG1516	flagellar protein fliS
J9312_18380	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J9312_18385	COG1334	flagellar protein FlaG
J9312_18390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J9312_18395	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
J9312_18400	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
J9312_18410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J9312_18415	COG1256	bacterial-type flagellum assembly
J9312_18415	COG4786	Flagellar basal body rod
J9312_18420	COG3418	PFAM FlgN family protein
J9312_18425	COG2747	anti-sigma28 factor FlgM
J9312_18435	COG1040	competence protein
J9312_18445	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
J9312_18450	COG1307	EDD domain protein, DegV family
J9312_18455	COG2197	response regulator
J9312_18460	COG4585	Histidine kinase
J9312_18465	COG1739	Uncharacterized protein family UPF0029
J9312_18470	COG1316	TRANSCRIPTIONal
J9312_18500	COG1131	(ABC) transporter
J9312_18510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J9312_18515	COG0438	transferase activity, transferring glycosyl groups
J9312_18520	COG1215	transferase activity, transferring glycosyl groups
J9312_18525	COG3206	protein involved in exopolysaccharide biosynthesis
J9312_18530	COG3307	-O-antigen
J9312_18535	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J9312_18540	COG0297	glycogen (starch) synthase activity
J9312_18540	COG0438	transferase activity, transferring glycosyl groups
J9312_18545	COG2244	polysaccharide biosynthetic process
J9312_18555	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_18555	COG2247	cell wall binding repeat
J9312_18560	COG2247	cell wall binding repeat
J9312_18560	COG2385	sporulation resulting in formation of a cellular spore
J9312_18575	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J9312_18580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J9312_18590	COG1134	teichoic acid transport
J9312_18595	COG1682	transport, permease protein
J9312_18610	COG0463	Glycosyl transferase, family 2
J9312_18610	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J9312_18615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J9312_18620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J9312_18625	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J9312_18630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J9312_18635	COG4193	domain, Protein
J9312_18640	COG1482	cell wall glycoprotein biosynthetic process
J9312_18645	COG0697	spore germination
J9312_18650	COG0814	amino acid
J9312_18665	COG1316	TRANSCRIPTIONal
J9312_18670	COG0561	phosphatase activity
J9312_18675	COG0791	NLP P60 protein
J9312_18685	COG2843	Capsule synthesis protein
J9312_18695	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J9312_18700	COG1609	Transcriptional regulator
J9312_18705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9312_18710	COG1869	D-ribose catabolic process
J9312_18715	COG1129	ABC transporter
J9312_18720	COG1172	Belongs to the binding-protein-dependent transport system permease family
J9312_18730	COG3103	Sh3 type 3 domain protein
J9312_18740	COG2249	NAD(P)H dehydrogenase (quinone) activity
J9312_18745	COG3527	Alpha-acetolactate decarboxylase
J9312_18750	COG0028	Belongs to the TPP enzyme family
J9312_18755	COG0583	DNA-binding transcription factor activity
J9312_18760	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J9312_18775	COG5337	Spore coat protein CotH
J9312_18785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J9312_18795	COG0405	Gamma-glutamyltransferase
J9312_18800	COG1522	sequence-specific DNA binding
J9312_18805	COG2059	Chromate
J9312_18810	COG2059	Chromate
J9312_18825	COG0583	DNA-binding transcription factor activity
J9312_18830	COG1515	deoxyribonuclease V activity
J9312_18855	COG5444	nuclease activity
J9312_18875	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J9312_18880	COG4464	protein tyrosine phosphatase activity
J9312_18885	COG0489	protein tyrosine kinase activity
J9312_18890	COG3944	biosynthesis protein
J9312_18900	COG4715	Zinc finger, swim domain protein
J9312_18905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J9312_18910	COG0561	phosphatase activity
J9312_18915	COG1349	DNA-binding transcription factor activity
J9312_18920	COG0629	single-stranded DNA binding
J9312_18935	COG3764	Sortase (surface protein transpeptidase)
J9312_18945	COG0745	RESPONSE REGULATOR receiver
J9312_18945	COG2972	Histidine kinase
J9312_18950	COG1970	mechanosensitive ion channel activity
J9312_18955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J9312_18960	COG0457	Tetratricopeptide repeat
J9312_18965	COG4786	Flagellar basal body rod
J9312_18970	COG4786	Flagellar basal body rod
J9312_18975	COG1077	Cell shape determining protein MreB Mrl
J9312_18980	COG1609	Transcriptional regulator
J9312_18990	COG1846	Transcriptional regulator
J9312_18995	COG2814	Major facilitator Superfamily
J9312_19000	COG3420	alginic acid biosynthetic process
J9312_19005	COG1953	Uracil, thiamine, allantoin
J9312_19010	COG0477	Major facilitator Superfamily
J9312_19015	COG1335	isochorismatase
J9312_19025	COG0004	ammonium transporteR
J9312_19030	COG0347	Belongs to the P(II) protein family
J9312_19035	COG0671	phosphoesterase, PA-phosphatase related
J9312_19045	COG0739	heme binding
J9312_19050	COG1247	-acetyltransferase
J9312_19060	COG2089	acid synthase
J9312_19070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J9312_19075	COG0789	Transcriptional regulator
J9312_19090	COG1959	2 iron, 2 sulfur cluster binding
J9312_19095	COG0804	urea catabolic process
J9312_19100	COG0832	Belongs to the urease beta subunit family
J9312_19105	COG0831	urea catabolic process
J9312_19120	COG3237	CsbD-like
J9312_19125	COG1994	Peptidase M50
J9312_19130	COG0457	Tetratricopeptide repeat
J9312_19135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J9312_19140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J9312_19150	COG2304	oxidoreductase activity
J9312_19160	COG2304	oxidoreductase activity
J9312_19165	COG2385	sporulation resulting in formation of a cellular spore
J9312_19170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J9312_19180	COG4836	Membrane
J9312_19190	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J9312_19195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J9312_19200	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J9312_19205	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J9312_19210	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J9312_19215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J9312_19225	COG0356	it plays a direct role in the translocation of protons across the membrane
J9312_19235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J9312_19240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J9312_19245	COG4475	Protein of unknown function (DUF436)
J9312_19250	COG0698	ribose 5-phosphate isomerase
J9312_19255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J9312_19260	COG1971	Probably functions as a manganese efflux pump
J9312_19265	COG0009	L-threonylcarbamoyladenylate synthase
J9312_19270	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J9312_19290	COG2890	protein-(glutamine-N5) methyltransferase activity
J9312_19295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J9312_19300	COG0346	lactoylglutathione lyase activity
J9312_19305	COG0789	Transcriptional regulator
J9312_19310	COG0679	Auxin Efflux Carrier
J9312_19315	COG0281	malic enzyme
J9312_19320	COG1435	thymidine kinase activity
J9312_19330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J9312_19340	COG1494	fructose-1,6-bisphosphatase
J9312_19345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J9312_19350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J9312_19355	COG0191	fructose-bisphosphate aldolase activity
J9312_19360	COG2204	response regulator
J9312_19365	COG4821	SIS domain
J9312_19375	COG0504	CTP synthase activity
J9312_19380	COG3343	RNA polymerase activity
J9312_19385	COG1960	acyl-CoA dehydrogenase activity
J9312_19390	COG0247	lactate metabolic process
J9312_19390	COG2181	nitrate reductase activity
J9312_19395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J9312_19400	COG4294	response to UV
J9312_19410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J9312_19420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J9312_19430	COG2181	nitrate reductase activity
J9312_19435	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
J9312_19440	COG1140	nitrate reductase beta subunit
J9312_19445	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
J9312_19450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J9312_19460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J9312_19465	COG2223	nitrite transmembrane transporter activity
J9312_19470	COG0018	arginyl-trna synthetase
J9312_19475	COG4506	Protein conserved in bacteria
J9312_19490	COG0535	radical SAM domain protein
J9312_19500	COG1131	(ABC) transporter
J9312_19505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J9312_19510	COG0612	Peptidase, M16
J9312_19515	COG0612	Peptidase, M16
J9312_19525	COG3391	amine dehydrogenase activity
J9312_19530	COG3391	amine dehydrogenase activity
J9312_19535	COG0457	Tetratricopeptide repeat
J9312_19545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J9312_19550	COG0010	Belongs to the arginase family
J9312_19555	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J9312_19560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J9312_19570	COG1994	Peptidase M50
J9312_19575	COG1942	4-Oxalocrotonate Tautomerase
J9312_19580	COG1846	Transcriptional regulator
J9312_19585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J9312_19590	COG0477	Major facilitator Superfamily
J9312_19595	COG1959	2 iron, 2 sulfur cluster binding
J9312_19600	COG3465	dGTPase activity
J9312_19605	COG1078	dGTPase activity
J9312_19610	COG4844	belongs to the
J9312_19620	COG0697	spore germination
J9312_19625	COG0095	Lipoate-protein ligase
J9312_19630	COG0583	DNA-binding transcription factor activity
J9312_19635	COG0280	phosphate acetyltransferase
J9312_19640	COG3253	May function as heme-dependent peroxidase
J9312_19645	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_19650	COG0436	Aminotransferase
J9312_19655	COG2814	Major facilitator Superfamily
J9312_19660	COG0151	Belongs to the GarS family
J9312_19665	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_19670	COG1917	Cupin 2, conserved barrel domain protein
J9312_19675	COG0077	Prephenate dehydratase
J9312_19680	COG2814	Major facilitator Superfamily
J9312_19685	COG0833	amino acid
J9312_19690	COG4187	Peptidase family M20/M25/M40
J9312_19695	COG1012	belongs to the aldehyde dehydrogenase family
J9312_19700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J9312_19710	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
J9312_19715	COG1091	dTDP-4-dehydrorhamnose reductase activity
J9312_19720	COG1088	dTDP-glucose 4,6-dehydratase activity
J9312_19725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J9312_19730	COG3980	spore coat polysaccharide biosynthesis protein
J9312_19735	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
J9312_19740	COG2089	acid synthase
J9312_19745	COG0456	acetyltransferase
J9312_19750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J9312_19755	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J9312_19760	COG0463	Glycosyl transferase, family 2
J9312_19775	COG2363	Small membrane protein
J9312_19780	COG2233	PERMEase
J9312_19790	COG1012	belongs to the aldehyde dehydrogenase family
J9312_19795	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J9312_19800	COG1216	Glycosyl transferase, family 2
J9312_19815	COG1695	Transcriptional regulator
J9312_19820	COG0351	phosphomethylpyrimidine kinase
J9312_19830	COG1621	beta-fructofuranosidase activity
J9312_19835	COG1263	PTS System
J9312_19835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_19840	COG2116	formate transmembrane transporter activity
J9312_19845	COG3711	transcriptional antiterminator
J9312_19855	COG1404	Belongs to the peptidase S8 family
J9312_19860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J9312_19865	COG0778	Nitroreductase
J9312_19870	COG0772	Belongs to the SEDS family
J9312_19885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J9312_19890	COG1845	cytochrome c oxidase, subunit III
J9312_19895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J9312_19900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J9312_19905	COG2261	transglycosylase associated protein
J9312_19910	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
J9312_19915	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J9312_19920	COG2246	polysaccharide biosynthetic process
J9312_19925	COG1309	transcriptional regulator
J9312_19935	COG3162	membrane
J9312_19940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J9312_19945	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J9312_19950	COG2837	iron assimilation
J9312_19955	COG2822	iron ion transport
J9312_19960	COG0672	)-iron permease
J9312_19965	COG0352	thiamine-phosphate diphosphorylase activity
J9312_19970	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J9312_19975	COG0583	DNA-binding transcription factor activity
J9312_19980	COG1380	Effector of murein hydrolase LrgA
J9312_19985	COG1346	cytolysis
J9312_19990	COG2814	Major facilitator Superfamily
J9312_19995	COG4895	conserved protein (DUF2196)
J9312_20000	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J9312_20005	COG0346	lactoylglutathione lyase activity
J9312_20015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J9312_20020	COG1404	Belongs to the peptidase S8 family
J9312_20025	COG1263	PTS System
J9312_20025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_20030	COG3711	transcriptional antiterminator
J9312_20035	COG1442	glycosyl transferase family 8
J9312_20040	COG5522	Integral membrane protein (intg_mem_TP0381)
J9312_20045	COG1846	Transcriptional regulator
J9312_20050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J9312_20055	COG2234	aminopeptidase activity
J9312_20060	COG2357	RelA SpoT domain protein
J9312_20070	COG1575	Belongs to the MenA family. Type 1 subfamily
J9312_20085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_20090	COG1696	Membrane protein involved in D-alanine export
J9312_20095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J9312_20100	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
J9312_20105	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J9312_20110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J9312_20115	COG1486	melibiose metabolic process
J9312_20120	COG1447	Phosphotransferase system cellobiose-specific component IIA
J9312_20125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J9312_20130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J9312_20135	COG3711	transcriptional antiterminator
J9312_20135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_20145	COG2094	Belongs to the DNA glycosylase MPG family
J9312_20150	COG0753	catalase activity
J9312_20155	COG2814	Major facilitator Superfamily
J9312_20160	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J9312_20165	COG1131	(ABC) transporter
J9312_20185	COG1595	DNA-templated transcription, initiation
J9312_20190	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J9312_20195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J9312_20200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J9312_20205	COG4988	ABC transporter
J9312_20210	COG1294	oxidase, subunit
J9312_20215	COG1271	oxidase subunit
J9312_20220	COG3493	citrate carrier protein
J9312_20225	COG0501	Belongs to the peptidase M48B family
J9312_20235	COG0726	polysaccharide deacetylase
J9312_20245	COG3842	ATPase activity
J9312_20250	COG2508	Transcriptional regulator
J9312_20255	COG1012	belongs to the aldehyde dehydrogenase family
J9312_20260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_20265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J9312_20275	COG4585	Histidine kinase
J9312_20280	COG2197	response regulator
J9312_20285	COG2195	Cleaves the N-terminal amino acid of tripeptides
J9312_20295	COG4894	glucomannan catabolic process
J9312_20300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J9312_20305	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J9312_20310	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_20315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J9312_20320	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J9312_20325	COG2610	gluconate transmembrane transporter activity
J9312_20330	COG0500	methyltransferase
J9312_20335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J9312_20350	COG0693	protein deglycase activity
J9312_20350	COG0753	catalase activity
J9312_20355	COG2851	Citrate transporter
J9312_20360	COG2273	Hydrolase Family 16
J9312_20365	COG3711	transcriptional antiterminator
J9312_20375	COG2270	Major facilitator Superfamily
J9312_20380	COG0513	Belongs to the DEAD box helicase family
J9312_20385	COG3401	FG-GAP repeat protein
J9312_20385	COG2755	lipolytic protein G-D-S-L family
J9312_20505	COG0697	spore germination
J9312_20510	COG0589	response to stress
J9312_20530	COG5444	nuclease activity
J9312_20565	COG3507	Belongs to the glycosyl hydrolase 43 family
J9312_20575	COG1228	amidohydrolase
J9312_20580	COG0010	Belongs to the arginase family
J9312_20585	COG0833	amino acid
J9312_20590	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J9312_20595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J9312_20600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J9312_20605	COG2390	Transcriptional regulator
J9312_20615	COG3192	ethanolamine utilization protein
J9312_20620	COG2079	MmgE PrpD family protein
J9312_20625	COG1473	amidohydrolase
J9312_20630	COG1126	abc transporter atp-binding protein
J9312_20635	COG0765	amino acid transport
J9312_20640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J9312_20645	COG0456	acetyltransferase
J9312_20650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J9312_20655	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
J9312_20660	COG0561	phosphatase activity
J9312_20690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_20695	COG5294	Protein conserved in bacteria
J9312_20700	COG0577	efflux transmembrane transporter activity
J9312_20705	COG1136	(ABC) transporter
J9312_20710	COG2205	protein histidine kinase activity
J9312_20720	COG0191	fructose-bisphosphate aldolase activity
J9312_20725	COG1082	Xylose isomerase domain protein TIM barrel
J9312_20730	COG1082	Xylose isomerase domain protein TIM barrel
J9312_20735	COG0673	inositol 2-dehydrogenase activity
J9312_20745	COG1082	Xylose isomerase domain protein TIM barrel
J9312_20750	COG3962	Belongs to the TPP enzyme family
J9312_20755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9312_20770	COG1349	DNA-binding transcription factor activity
J9312_20775	COG0667	Aldo Keto reductase
J9312_20790	COG2814	Major facilitator Superfamily
J9312_20795	COG0326	Molecular chaperone. Has ATPase activity
J9312_20845	COG1309	transcriptional regulator
J9312_20850	COG1012	belongs to the aldehyde dehydrogenase family
J9312_20855	COG1714	RDD family
J9312_20865	COG1714	RDD family
J9312_20870	COG2311	Membrane
J9312_20875	COG1917	Cupin 2, conserved barrel domain protein
J9312_20880	COG1309	transcriptional regulator
J9312_20885	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_20890	COG1846	Transcriptional regulator
J9312_20895	COG1380	Effector of murein hydrolase LrgA
J9312_20900	COG1346	cytolysis
J9312_20905	COG5039	Polysaccharide pyruvyl transferase
J9312_20910	COG1929	Belongs to the glycerate kinase type-1 family
J9312_20915	COG1802	Transcriptional regulator
J9312_20920	COG1070	Carbohydrate kinase
J9312_20925	COG2610	gluconate transmembrane transporter activity
J9312_20930	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J9312_20935	COG0450	alkyl hydroperoxide reductase
J9312_20940	COG3634	alkyl hydroperoxide reductase activity
J9312_20945	COG2723	6-phospho-beta-galactosidase activity
J9312_20955	COG2188	Transcriptional regulator
J9312_20970	COG1131	(ABC) transporter
J9312_20975	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
J9312_20990	COG0071	Belongs to the small heat shock protein (HSP20) family
J9312_21025	COG0210	DNA helicase
J9312_21055	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J9312_21070	COG1063	alcohol dehydrogenase
J9312_21090	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
J9312_21095	COG0456	acetyltransferase
J9312_21100	COG0457	Tetratricopeptide repeat
J9312_21110	COG0010	Belongs to the arginase family
J9312_21115	COG0833	amino acid
J9312_21120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J9312_21140	COG5658	integral membrane protein
J9312_21145	COG0640	Transcriptional regulator
J9312_21150	COG3829	transcription factor binding
J9312_21165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9312_21170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J9312_21175	COG4853	Protein conserved in bacteria
J9312_21180	COG4863	YycH protein
J9312_21185	COG5002	protein histidine kinase activity
J9312_21190	COG0745	RESPONSE REGULATOR receiver
J9312_21220	COG0346	lactoylglutathione lyase activity
J9312_21225	COG0305	Participates in initiation and elongation during chromosome replication
J9312_21240	COG3093	addiction module antidote protein HigA
J9312_21245	COG2807	transmembrane transport
J9312_21250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J9312_21255	COG0359	binds to the 23S rRNA
J9312_21260	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
J9312_21280	COG1733	regulation of RNA biosynthetic process
J9312_21285	COG1227	inorganic diphosphatase activity
J9312_21300	COG2271	Major facilitator Superfamily
J9312_21305	COG0789	Transcriptional regulator
J9312_21305	COG4978	Transcriptional regulator
J9312_21315	COG4319	ketosteroid isomerase
J9312_21320	COG1357	PFAM Pentapeptide repeats (8 copies)
J9312_21335	COG1846	Transcriptional regulator
J9312_21340	COG2153	protein acetylation
J9312_21345	COG2364	Membrane
J9312_21350	COG0456	acetyltransferase
J9312_21355	COG2315	Protein conserved in bacteria
J9312_21360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J9312_21370	COG2814	Major facilitator Superfamily
J9312_21380	COG1331	Highly conserved protein containing a thioredoxin domain
J9312_21385	COG1266	CAAX protease self-immunity
J9312_21390	COG0477	Major facilitator Superfamily
J9312_21390	COG2814	Major facilitator Superfamily
J9312_21395	COG0110	maltose O-acetyltransferase activity
J9312_21400	COG0346	lactoylglutathione lyase activity
J9312_21405	COG1609	Transcriptional regulator
J9312_21410	COG0708	Exodeoxyribonuclease III
J9312_21415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J9312_21420	COG0629	single-stranded DNA binding
J9312_21425	COG0360	Binds together with S18 to 16S ribosomal RNA
J9312_21430	COG0012	GTP binding
J9312_21435	COG0243	molybdopterin cofactor binding
J9312_21440	COG4481	Protein conserved in bacteria
J9312_21445	COG3949	Membrane
J9312_21455	COG1475	DNA binding
J9312_21460	COG1192	Involved in chromosome partitioning
J9312_21470	COG1475	DNA binding
J9312_21475	COG0357	Ribosomal RNA small subunit methyltransferase G
J9312_21480	COG0445	tRNA wobble uridine modification
J9312_21485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J9312_21490	COG1847	R3H domain protein
J9312_21495	COG0706	membrane insertase activity
J9312_21500	COG0594	ribonuclease P activity